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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_0.mp3
To put a bow tie in Constantinople, it went from a very low population of maybe 25,000 people to 500,000 people in just two centuries. So can you explain how that happened?
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_1.mp3
Well, it didn't happen through, um, just, um, demographic growth and reproduction in the city itself. That rate of growth is impossible for an ancient city. So when I say 20, 25,000, that's,
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_2.mp3
Possibly what the ancient city of Byzantium had when Constantine decided to found Constantinople. And it grew to a city of a half a million in two centuries.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_3.mp3
That can only have been done in one way, and that is emigration from the provinces. So people must have been moving there, um, in, in large numbers.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_4.mp3
Which is a movement that we can't see very clearly in the sources, but we have to infer it and then try to explain it.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_5.mp3
So, um, also there's another factor, which is that ancient cities we now know or suspect
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_6.mp3
are what some historians call death traps. In other words, the density of disease is such that ancient cities probably are losing something like one to possibly 3% of their population per year.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_7.mp3
So, just in order to stay with a stable population, they have to import people, right?
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_8.mp3
They're not like 17th century London. They're not that bad.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_9.mp3
Those diseases and plagues seem to be prevalent. Oh, yeah.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_10.mp3
You know, Roman cities have some corrections for these sorts of things.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_11.mp3
But, there's that. So, not only to keep the population steady, but to expand it so dramatically means that a lot of people are coming in from the provinces, mostly the Greek speaking provinces. So, you know, Greece, Asia Minor, and some of the major cities in the East that are Greek speaking.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_12.mp3
And I started wondering, like, well, how did this happen? Like, who are these people for one thing? And then I did some.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_13.mp3
Simple calculations. So I mentioned earlier that we have something like two and a half thousand senators, um, who are required initially to reside in Constantinople.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_14.mp3
Well, senators don't live in bachelor pants. Senators have manners. They have household staff, right? In Rome at the time, there's a calculation that a senatorial household was something like a hundred people.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_15.mp3
Right. Just servants, slaves, dancing girls, cooks, barbers, whatever. Right. So let's assume sort of conservatively that in Constantinople, it's only 30 people, which it might be low. Right. So if you do the math, you're starting to get something like, I mean, closer to a hundred thousand people.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_16.mp3
Right? And that's just by bringing in senators. Right? They come with people. Uh, so, I think this was the nucleus.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_17.mp3
Of the population. Now then Constantine also makes provision for possibly up to like 200,000 people to receive the, the grain doll, the bread.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_18.mp3
Um, so that would have incentivized even more people to travel there, because there are.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_19.mp3
Yes. And you can't live on that alone, but it is, it's something.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_20.mp3
Yeah. Is it true that he diverted resources from Rome to Constantinople? Absolutely.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_21.mp3
Absolutely. Oh yeah. That grain, that's coming from Egypt.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_22.mp3
So, New Rome is literally stealing food from the mouth of Old Rome. Yeah.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_23.mp3
Now, Old Rome doesn't starve because they, they divert other, like, from North Africa and Sicily, you can feed Rome, right?
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_24.mp3
But it sends a strong signal to the people living in an older home that long-term should probably move.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_25.mp3
Some people do move, so we know of some senators who moved from Rome.
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The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]/The rise of the Roman Empire in the East | Anthony Kaldellis and Lex Fridman [yHFSoMVD3HM]_26.mp3
Um, it sends a signal about the priorities of the state, like they're investing much more in the East and that the East would be regarded as a equal parallel Roman, you know, world.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_0.mp3
Just recently we've been talking about this, uh, over-optimizers. I saw Chris Williams on Modern Wisdom had a bit where he was like, yeah, okay, maybe we did go a little overboard. And the triggering thing was the diary of a CEO where the host was saying something to the effect of I had a glass of wine and the next th...
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_1.mp3
And that to me, I mean, in his circumstance, I'm sure that's true. Like, if you have not.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_2.mp3
Drank any alcohol for a very long time. And you have just a little, I could see how it can have effect. But also there's something in that to just.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_3.mp3
We've all stopped drinking apparently, like alcohol sales are way down. Certainly amongst young people.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_4.mp3
And then, on the one hand, on the pure health metrics, whatever, we can go like, oh wow, isn't that great? And then I go like, yeah, I'm not so sure it is. Like, the social lubricant that alcohol can provide.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_5.mp3
Maybe missed is missed. I mean, we are in an absolute epidemic of loneliness and misery and depression and whatever. And a fair amount of it just probably comes because you're not interacting enough with other people. Now that's before we even talk about coupling, right? Like, uh, way down.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_6.mp3
People having a very hard time meeting as spouses. A lot of that has moved over to apps that have all sorts of.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_7.mp3
negative outcomes and consequences, right? Like, maybe we will look back or maybe where we are looking back and thinking like, ah, do you know what? Maybe getting wasted every once in a while was not the worst thing in the world. And whether wasted or not, maybe just having a couple of drinks every
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_8.mp3
Friday or Saturday when you're out and about was.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_9.mp3
The fact that humans have literally been drinking for whatever it is, like a 13,000 years from mending things had a social purpose. And we pull out Chestersons fence of our own chagrin, right?
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_10.mp3
As you mentioned in the spirit of that. So when I traveled across rural China, I did smoke a little bit in my early twenties, but I picked up just for that trip. A social.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_11.mp3
Connector, right? And I drink humongous amounts, even though I don't really drink these days.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_12.mp3
Because of the social thing, it's the way they show love. Yes. And I also eat shit load of carbs, which I'm usually low carb, but I just like me. So just because it's the way they show love and actually even in that society, uh, cigarettes.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_13.mp3
But in most societies, liquor is a thing to do together.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_14.mp3
Can, in many situations, outweigh the negative consequences, like long term, for whatever, however you measure them.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_15.mp3
And this is the myopia of modernity that we reduce things down to like, well, one class on this long run study meant that you had a 0.1% greater risk of some heart defect. Yes. But if you didn't live at all, what's the point? And again.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_16.mp3
It's also easy to flip over the other side. Like the only way to live is to get drunk every weekend and eat a bunch of crap and smoke 40 cigarettes a day. No, it's not. Like it doesn't have to be the either or. This is one of the reasons I stopped wearing my aura ring. So I wore the aura sleep ring for many years, fou...
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_17.mp3
I don't want to call it anxiety. I don't have a lot of anxiety, but this adage is like reminder that I had a bad night of sleep. What purpose is it actually playing here? Why do I need to have all these stats? Why do I need to optimize everything to the point where again, after that,
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_18.mp3
Single antidote, you know, from Dyer River to CEO. I was like, fuck, I kind of want the opposite. Like.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_19.mp3
Yeah. I don't barely drink at all. I, a glass of wine once a month, maybe. Like, do you know when I should start, uh, just.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_20.mp3
On the weekends, get a glass, maybe two. Yeah. And also, I mean, I've never been the person to fret about my diet. Um, this is one of the great privileges of being married to, and I'll do a quick aside here.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_21.mp3
Don't ever call a woman in her, in her forties a wonderful woman. My wife was so pissed that not only last year that I come on her birthday, that was bad enough, but that I called her a wonderful woman on the show because that sounded like her name was Nancy and she was 65 in the suburb of Rochester. So I'm like.
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_22.mp3
quite stable through several tens of thousands of years in human societies, that perhaps also wasn't the worst idea in the world. And I also know there are plenty of men who like to cook and there are women who don't, but as stereotypes go, eh,
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_23.mp3
Relatively healthy on a regular basis. But the overall point being just getting out of that optimization game without turning in
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DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]/DHH on danger of over-optimizing life | Lex Fridman Podcast Clips [zFsqzgyg14M]_24.mp3
To the opposite. You don't have to be a fat slob on the couch either. You can move around.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_0.mp3
How many people in the black regiments, but also, you know, folks like Frederick Douglass saw that black Americans and white Americans should have equal rights.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_1.mp3
Well, Douglas saw that, of course, but even within their context, their notion of equal rights is that that doesn't mean that black women are going to vote. Just like for white people, it didn't mean white women would vote. But in terms of the context of the time, yes.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_2.mp3
Equal rights should come out of this. Abolishing slavery is the first step of this. It's not the end game. The end game is.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_3.mp3
equal rights for everybody. Did many people see that? No, tiny percentage of people saw that.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_4.mp3
There's a notion that's very common that somehow the white North turned its back on black people after the war. And it should have tried harder during reconstruction to force the white South to convey full equal rights to black people. The assumption there is simply flawed. Most white people in the North didn't believ...
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_5.mp3
that they believe first saved the union and yes, we'll need to kill slavery as well. Those are the two things on the list. Check, check. We've done those full equal rights for black people is not on their list that it, and they were not willing to do the things that would have taken to do that.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_6.mp3
including the white soldiers in uniforms who wanted out of the army after the Confederacy surrendered and said, well, now we need the army to make the white South do the right thing vis-a-vis black people. They would have said, what are you talking about?
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_7.mp3
I signed on to do this. We did it. Send us home. Right now.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_8.mp3
I think that's one of the lessons you learn from human history across the different places where slavery was abolished is, uh,
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_9.mp3
Abolishing slavery is not the end of a journey. It's the beginning of a journey. And then sometimes takes quite often takes at least a hundred years to go from that to something you would identify as equal rights. And then maybe even beyond that, there's a complicated story about.
96.682094
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_10.mp3
There's a difference between passing. I mean, the great society passed most of it. You've got the Civil Rights Act, the Voting Rights Act, Fair Housing Act. You got all of this legislation that does a lot of the legal stuff, but it's what's in people's heads that takes longer and is a, is a more frustrating process.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_11.mp3
Potential fuel for the division to rise up again.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_12.mp3
Of course. And then people can exploit that. It's, it's waiting to be exploited and people exploit it.
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Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]/Racism in America after slavery was abolished | Gary Gallagher and Lex Fridman [g_RuCq-vq9I]_13.mp3
This is something we do as humans. We like to otherize certain groups. Good to have an enemy. And the civil war for our country is the story of this. It's, uh, so understanding the civil war is in part extremely important for understanding the, the division, maybe the dormant division that's there.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_0.mp3
The drug companies came, came across a new class of antidepressants that didn't have those side effects. As we'll see, they had other side effects, but not those. And the most famous of those was Prozac.
6.325344
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_1.mp3
Serotonin is something manufactured in our bodies, actually in our digestive system, and it performs a variety of functions in the body, but it's also one of the neurotransmitters in our brains.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_2.mp3
slowing the reuptake of serotonin in the brain.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_3.mp3
Which was m, marketed by the drug companies as the solution to depression. That when you got depressed.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_4.mp3
Uh, which still are the most prescribed antidepressants. Do they work and what are the side effects? Yeah. So here's where we get into slippery territory. Every time you do a controlled study of these antidepressants, they beat placebo.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_5.mp3
Does that mean clinically or does it mean statistically? Because the fact, if you.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_6.mp3
When we measure improvement with depression, we tend to use rating scales of various sorts. Um, and if you improve on one of the major scales that's used, by one or two points.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_7.mp3
on a 60 point scale. It may be enough to show statistical significance. There's drugs that look a little better than placebo.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_8.mp3
I'm marginally better than placebo, but a lot of the effect is the placebo effect. And they come with.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_9.mp3
Very difficult side effects. A lot of people describe them as numbing drugs. They flatten everything out.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_10.mp3
The numbing extends elsewhere in your body. In particular, lots of patients find, um, a complete loss of libido. They, they have, they're, they can't.
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3.10792
Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_11.mp3
Get an erection. They can't climax if they're a woman. Their sex life just goes away.
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3.173949
Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_12.mp3
And so many patients find themselves trapped on those trucks for a long time and we don't know what the effects of that are going to be. So it's a very mixed picture. You know, uh, that's why I think groups like Nice in England are saying,
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_13.mp3
It's like this with both antipsychotics and antidepressants. You have a group of people who respond pretty well.
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3.064998
Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_14.mp3
So drugs aren't doing anything for them and they're running a risk. And then in the middle, you have a group of people who get some positive improvement, but they also get side effects.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_15.mp3
You don't know which group you're going to fall in and your, and your doctor doesn't know which group you're going to fall in. And more importantly, one of the things that drugs revolution did was it moved.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_16.mp3
The diagnosis and the prescribing of things.
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Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]/Side-effects of SSRI antidepressant drugs: Sex-life plummets | Andrew Scull and Lex Fridman [AAeUY9XeyzM]_17.mp3
Away from psychiatry alone, so many of these things, particularly antidepressants, are dispensed by primary care docs, not, not psychiatrists.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_0.mp3
So he didn't launch wars of conquest. What was his view of war?
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_1.mp3
And conquest and what, um, maybe what are the things we should mention in terms of expansionary wars?
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_2.mp3
He thought he was authorized by God to reconquer the lost provinces of the Western Roman Empire. And when he did so, that was proof that God favored him.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_3.mp3
And he was generally opportunistic about it. Uh, and for the most part, kind of successful in that he, he intervened in the most critical moments of the histories of these barbarian, you know, kingdoms in the West.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_4.mp3
and exploited their weaknesses and took them over. Now, in the process, many of these provinces were ravaged by war, Italy for decades.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_5.mp3
Um, he overstretched his resources, leaving his successors with a much more dangerous, um, uh, situation to defend. Um, and he, he disbanded certain armies that were meant to protect Constantinople, sent them to Italy, for example. This weakened the home front.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_6.mp3
Um, so he left a very difficult legacy for his successors in that way. Plus some of the provinces that he conquered were so, like Italy, I don't think it could even pay for itself after a certain point. Um, so I'm not sure that some of those decisions were the best ones. North Africa? Yeah, probably that paid off. Ita...
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_7.mp3
So that's one of the big criticisms is even though there was conquest, it was overextended and those lands were not economically stable.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_8.mp3
Yeah. And broke. Yeah. AKA. Conquest is not just good, you know, in itself. I mean, this is, I know that some rulers in history are called the great simply because they conquered something, but that's, that's not enough. I mean, I know that rulers do this.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_9.mp3
But if we're to compare them to each other, we should at least expect that they have a plan or that it works out well in the end, let's say. And I don't think that many of these did.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_10.mp3
I should say that, uh, as far as historians go, I think you don't give too many points on the conquest front.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_11.mp3
Was he good for his subjects? Yeah. Were they living better because of him than otherwise?
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_12.mp3
And also like longer, like the long-term nature of it, not just, not just like a temporary thing.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_13.mp3
Right. Are you strengthening institutions that benefit your subjects?
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_14.mp3
And some he did, some not. So look, in order to send those armies west to make those conquests, he stripped the east of, of armies. So the Persians could just march in and like destroyed Antioch. Like that's a major strategic failure.
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Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]/Wars of conquest that weakened the Roman Empire | Anthony Kaldellis and Lex Fridman [MUoAmcBEloY]_15.mp3
And I don't think you get a pass for conquering North Africa by surrendering Syria.
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End of preview. Expand in Data Studio

YouTube Audio Processed Dataset

This dataset contains high-quality segmented speech datasets preprocessed from YouTube videos using the Emilia preprocessor framework.

Dataset Structure

Each row in the dataset contains a segmented audio clip, its aligned high-fidelity transcript, speaker labeling, and objective speech quality assessment scores.

Features

  • file_name: Audio column containing the relative path to the segmented .mp3 clip.
  • text: The corresponding transcribed text (using WhisperX / Emilia pipeline).
  • start: The start time of the segment in the source audio (seconds).
  • end: The end time of the segment in the source audio (seconds).
  • speaker: Assigned speaker tag (e.g., SPEAKER_00, SPEAKER_01) from diarization.
  • language: Detected language code (e.g., en).
  • dnsmos: Objective Deep Noise Suppression Mean Opinion Score (indicating vocal quality; higher is better).

Processing Pipeline

  1. Download: Acquired via yt-dlp using numerical formats.
  2. Diarization & Alignment: Segmented with PyAnnote Audio diarization and aligned via WhisperX.
  3. Filtering: Post-processed using DNSMOS filtering to eliminate low-quality audio fragments.

(Metadata version: 1.0.1)

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