EpiScope β€” arbovirus & glaucoma diagnostic models

Model artifacts produced by EpiScope, a clinical decision-support system for arboviruses (dengue, zika, chikungunya) and glaucoma. The same models are served by a Flask/GraphQL API and β€” for the Web3 build β€” inside the Cartesi Machine (RISC-V), so a diagnosis can be executed and verified on-chain instead of being trusted.

EpiScope won 1st place in the Cartesi Rollups Challenge (Cartesi Β· UFBA Β· Tomorrow Β· Positivo Tecnologia, 2025).

Tabular models (symptom + lab triage)

file estimator notes
tabular/randomforest.joblib RandomForestClassifier 100 trees, 15 features, 3 classes
tabular/xgboost_standard.joblib XGBClassifier 100 estimators, default search
tabular/xgboost_genetic.joblib XGBClassifier 188 estimators, hyperparameters found by a genetic algorithm (see metadata/best_hyperparameters.json)
tabular/xgboost_model.joblib XGBClassifier deployed model served by the API
tabular/decisiontree.joblib DecisionTreeClassifier interpretable baseline / rule extraction
  • Input features (15): febre, mialgia, cefaleia, exantema, vomito, nausea, dor_costas, conjuntvit, artrite, artralgia, petequia_n, leucopenia, dor_retro, sexo_encoded, idade
  • Target classes: 1=dengue, 0=zika, 2=chikungunya
  • Genetic search result: n_estimators=188, max_depth=3, learning_rate=0.1487, subsample=0.951, colsample_bytree=0.622, gamma=1.5385
import joblib, json
cols = json.load(open("metadata/model_columns.json"))
model = joblib.load("tabular/xgboost_genetic.joblib")
# X = [[...]] ordered exactly as `cols`
# print(model.predict_proba(X))  # [zika, dengue, chikungunya]

Glaucoma CNN

glaucoma/glaucoma_cnn_model.h5 β€” Keras CNN, input 224Γ—224, binary classification (Glaucomatous / Normal), see metadata/glaucoma_info.json.

How the models are used

  1. Symptom/lab payload or a fundus image comes in through the API.
  2. The tabular model and/or the CNN produce a diagnosis with per-class probabilities.
  3. Google Gemini narrates the result and explains the reasoning in natural language.
  4. In the DApp build, the same inference runs inside the Cartesi Machine and the result is committed through rollups β€” a verifiable, tamper-evident medical opinion.

Limitations

  • Decision support only, not a diagnostic device; no clinical validation or regulatory clearance.
  • Trained on public epidemiological data (symptom/lab surveillance), which is skewed to notified cases β€” prevalence in an unselected population differs.
  • The tabular models consume exactly the 15 features listed above; missing values must be handled upstream.

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