GeneFlow Checkpoints

Checkpoints for GeneFlow, a rectified-flow model that generates H&E histology image patches conditioned on gene expression (Xenium spatial transcriptomics). Companion to the NeurIPS 2025 paper.

Code: https://github.com/wangmengbo/GeneFlow

Checkpoints

Folder Sample Model type Epoch Val loss SSIM FID UNI2-h FID
P1_single/ XeniumP1 single-cell 80 0.0300 0.1991 12.25 25.44
C1_single/ XeniumC1 single-cell 42 0.0238 0.2584 12.40 26.32
C1_multi/ XeniumC1 multi-cell (patch) 80 0.0330 0.2884 39.21 91.06

All three checkpoints match or exceed the metrics reported in the paper for their corresponding configuration (Table 2 / Table 5).

Usage

Load with the training/inference code in the GitHub repo (rectified/rectified_main.py --only_inference or rectified/rectified_evaluate.py), pointing --model_path at the downloaded .pt file.

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