senchronoage

Senescence-enriched chronological-age predictor restricted to CpGs whose directions were concordant across in-vitro senescence, age and mortality analyses.

Predicts	chronological age
Species	Homo sapiens
Tissue	whole blood
Data type	DNA methylation
Model type	elastic net regression
Year	2026

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["senchronoage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Kasamoto, K., Gibson, J., Moqri, M., Smith, R. & Higgins-Chen, A.T. DNA methylation signatures of cellular senescence are not reversed by senolytic treatment. Aging Cell 25, e70430 (2026).

https://doi.org/10.1111/acel.70430