retroelementagev1

Whole-blood Retroelement-Age V1, trained by 10-fold-cross-validated elastic net on EPIC v1.0 CpGs annotated to HERV and active LINE elements.

Predicts chronological age
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type elastic net regression
Year 2024

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["retroelementagev1"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Ndhlovu, Lishomwa C., et al. "Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements." Aging Cell 23 (2024): e14288.

https://doi.org/10.1111/acel.14288

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