pasta

Human Pasta age-shift classifier applied to within-sample rank-transformed expression. It converts a ridge-logistic older-versus-younger log-odds score to an age score.

Predicts	transcriptomic age
Species	Homo sapiens
Tissue	multi-tissue
Data type	transcriptomics
Model type	ridge logistic regression
Year	2025

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["pasta"])

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Citation

Salignon, J. et al. Pasta, a versatile transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation. bioRxiv 2025.06.04.657785 (2025).

https://doi.org/10.1101/2025.06.04.657785