neusin

Neu-Sin is a neuron semi-intrinsic chronological-age clock: elastic-net regression was restricted to neuron age-DMCTs but fitted to methylation values not adjusted for brain cell fractions.

Predicts chronological age
Species Homo sapiens
Tissue brain cortex
Data type DNA methylation
Model type elastic net regression
Year 2024

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["neusin"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 13452–13504.

https://doi.org/10.18632/aging.206184

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