mammalian1

Universal pan-mammalian clock 1: elastic-net regression of log-transformed chronological age on conserved mammalian-array CpGs, back-transformed to years.

Predicts	chronological age
Species	multiple species
Tissue	multi-tissue
Data type	DNA methylation
Model type	elastic net regression
Year	2023

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["mammalian1"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lu, A. T., et al. "Universal DNA methylation age across mammalian tissues." Nature Aging 3.9 (2023): 1144-1166.

https://doi.org/10.1038/s43587-023-00462-6