hrsinchphenoage

CpG-weighted HRS/InCHIANTI retraining of DNAm PhenoAge produced during the PC-clocks work; this implementation is not a principal-component clock.

Predicts phenotypic age
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type weighted linear score
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["hrsinchphenoage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Higgins-Chen, Albert T., et al. "A computational solution for bolstering reliability of epigenetic clocks: implications for clinical trials and longitudinal tracking." Nature Aging 2 (2022): 644–661.

https://doi.org/10.1038/s43587-022-00248-2

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