grimage

Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.

Predicts mortality risk
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type two-stage elastic net + Cox regression
Year 2019

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["grimage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lu, Ake T., et al. "DNA methylation GrimAge strongly predicts lifespan and healthspan." Aging (Albany NY) 11 (2019): 303–327.

https://doi.org/10.18632/aging.101684

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