ensembleagehumanmouse

Cross-species static EnsembleAge model trained on merged human and mouse methylation data; age is normalized by species maximum lifespan.

Predicts	relative age
Species	Homo sapiens and Mus musculus
Tissue	multi-tissue, whole blood
Data type	DNA methylation
Model type	elastic net regression
Year	2025

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["ensembleagehumanmouse"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Haghani, A. et al. EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework. GeroScience 48, 2873-2886 (2025).

https://doi.org/10.1007/s11357-025-01808-1