ctsliver

LiverClock is a liver tissue-specific chronological-age clock trained by lasso on age-associated CpGs identified after adjustment for five estimated liver cell fractions; unlike HepClock, it is not hepatocyte-specific.

Predicts chronological age
Species Homo sapiens
Tissue liver
Data type DNA methylation
Model type LASSO regression
Year 2024

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["ctsliver"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 14204–14237.

https://doi.org/10.18632/aging.206184

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