bohlin

Official minimum-lambda variant of the Bohlin gestational-age LASSO: pyaging implements the 251-CpG lambda.min model and converts its day-scale output to weeks. The paper/package default one-standard-error variant uses 96 CpGs and has nearly identical predictive performance.

Predicts	gestational age
Species	Homo sapiens
Tissue	cord blood
Data type	DNA methylation
Model type	LASSO regression
Year	2016

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["bohlin"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Bohlin, J., Håberg, S. E., Magnus, P. et al. Prediction of gestational age based on genome-wide differentially methylated regions. Genome Biology 17, 207 (2016).

https://doi.org/10.1186/s13059-016-1063-4