Daily Papers

Domain adaptation is to transfer the shared knowledge learned from the source domain to a new environment, i.e., target domain. One common practice is to train the model on both labeled source-domain data and unlabeled target-domain data. Yet the learned models are usually biased due to the strong supervision of the source domain. Most researchers adopt the early-stopping strategy to prevent over-fitting, but when to stop training remains a challenging problem since the lack of the target-domain validation set. In this paper, we propose one efficient bootstrapping method, called Adaboost Student, explicitly learning complementary models during training and liberating users from empirical early stopping. Adaboost Student combines the deep model learning with the conventional training strategy, i.e., adaptive boosting, and enables interactions between learned models and the data sampler. We adopt one adaptive data sampler to progressively facilitate learning on hard samples and aggregate "weak" models to prevent over-fitting. Extensive experiments show that (1) Without the need to worry about the stopping time, AdaBoost Student provides one robust solution by efficient complementary model learning during training. (2) AdaBoost Student is orthogonal to most domain adaptation methods, which can be combined with existing approaches to further improve the state-of-the-art performance. We have achieved competitive results on three widely-used scene segmentation domain adaptation benchmarks.

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but manual analysis of angiograms is prone to errors and subjectivity. This study aims to develop a deep learning-based approach for the automatic segmentation of coronary arteries from angiographic images and the quantitative detection of stenosis, thereby improving the accuracy and efficiency of CAD diagnosis. We propose a novel deep learning-based method for the automatic segmentation of coronary arteries in angiographic images, coupled with a dynamic cohort method for stenosis detection. The segmentation model combines the MedSAM and VM-UNet architectures to achieve high-performance results. After segmentation, the vascular centerline is extracted, vessel diameter is computed, and the degree of stenosis is measured with high precision, enabling accurate identification of arterial stenosis. On the mixed dataset (including the ARCADE, DCA1, and GH datasets), the model achieved an average IoU of 0.6308, with sensitivity and specificity of 0.9772 and 0.9903, respectively. On the ARCADE dataset, the average IoU was 0.6303, with sensitivity of 0.9832 and specificity of 0.9933. Additionally, the stenosis detection algorithm achieved a true positive rate (TPR) of 0.5867 and a positive predictive value (PPV) of 0.5911, demonstrating the effectiveness of our model in analyzing coronary angiography images. SAM-VMNet offers a promising tool for the automated segmentation and detection of coronary artery stenosis. The model's high accuracy and robustness provide significant clinical value for the early diagnosis and treatment planning of CAD. The code and examples are available at https://github.com/qimingfan10/SAM-VMNet.

Mental rotation -- the ability to compare objects seen from different viewpoints -- is a fundamental example of mental simulation and spatial world modelling in humans. Here we propose a mechanistic model of human mental rotation, leveraging advances in deep, equivariant, and neuro-symbolic learning. Our model consists of three stacked components: (1) an equivariant neural encoder, taking images as input and producing 3D spatial representations of objects, (2) a neuro-symbolic object encoder, deriving symbolic descriptions of objects from these spatial representations, and (3) a neural decision agent, comparing these symbolic descriptions to prescribe rotation simulations in 3D latent space via a recurrent pathway. Our model design is guided by the abundant experimental literature on mental rotation, which we complemented with experiments in VR where participants could at times manipulate the objects to compare, providing us with additional insights into the cognitive process of mental rotation. Our model captures well the performance, response times and behavior of participants in our and others' experiments. The necessity of each model component is shown through systematic ablations. Our work adds to a recent collection of deep neural models of human spatial reasoning, further demonstrating the potency of integrating deep, equivariant, and symbolic representations to model the human mind.

With the widespread use of mobile phones and scanners to photograph and upload documents, the need for extracting the information trapped in unstructured document images such as retail receipts, insurance claim forms and financial invoices is becoming more acute. A major hurdle to this objective is that these images often contain information in the form of tables and extracting data from tabular sub-images presents a unique set of challenges. This includes accurate detection of the tabular region within an image, and subsequently detecting and extracting information from the rows and columns of the detected table. While some progress has been made in table detection, extracting the table contents is still a challenge since this involves more fine grained table structure(rows & columns) recognition. Prior approaches have attempted to solve the table detection and structure recognition problems independently using two separate models. In this paper, we propose TableNet: a novel end-to-end deep learning model for both table detection and structure recognition. The model exploits the interdependence between the twin tasks of table detection and table structure recognition to segment out the table and column regions. This is followed by semantic rule-based row extraction from the identified tabular sub-regions. The proposed model and extraction approach was evaluated on the publicly available ICDAR 2013 and Marmot Table datasets obtaining state of the art results. Additionally, we demonstrate that feeding additional semantic features further improves model performance and that the model exhibits transfer learning across datasets. Another contribution of this paper is to provide additional table structure annotations for the Marmot data, which currently only has annotations for table detection.

Deep learning has transformed AI applications but faces critical security challenges, including adversarial attacks, data poisoning, model theft, and privacy leakage. This survey examines these vulnerabilities, detailing their mechanisms and impact on model integrity and confidentiality. Practical implementations, including adversarial examples, label flipping, and backdoor attacks, are explored alongside defenses such as adversarial training, differential privacy, and federated learning, highlighting their strengths and limitations. Advanced methods like contrastive and self-supervised learning are presented for enhancing robustness. The survey concludes with future directions, emphasizing automated defenses, zero-trust architectures, and the security challenges of large AI models. A balanced approach to performance and security is essential for developing reliable deep learning systems.

The ubiquity of large-scale Pre-Trained Models (PTMs) is on the rise, sparking interest in model hubs, and dedicated platforms for hosting PTMs. Despite this trend, a comprehensive exploration of the challenges that users encounter and how the community leverages PTMs remains lacking. To address this gap, we conducted an extensive mixed-methods empirical study by focusing on discussion forums and the model hub of HuggingFace, the largest public model hub. Based on our qualitative analysis, we present a taxonomy of the challenges and benefits associated with PTM reuse within this community. We then conduct a quantitative study to track model-type trends and model documentation evolution over time. Our findings highlight prevalent challenges such as limited guidance for beginner users, struggles with model output comprehensibility in training or inference, and a lack of model understanding. We also identified interesting trends among models where some models maintain high upload rates despite a decline in topics related to them. Additionally, we found that despite the introduction of model documentation tools, its quantity has not increased over time, leading to difficulties in model comprehension and selection among users. Our study sheds light on new challenges in reusing PTMs that were not reported before and we provide recommendations for various stakeholders involved in PTM reuse.

Many engineering organizations are reimplementing and extending deep neural networks from the research community. We describe this process as deep learning model reengineering. Deep learning model reengineering - reusing, reproducing, adapting, and enhancing state-of-the-art deep learning approaches - is challenging for reasons including under-documented reference models, changing requirements, and the cost of implementation and testing. In addition, individual engineers may lack expertise in software engineering, yet teams must apply knowledge of software engineering and deep learning to succeed. Prior work has examined on DL systems from a "product" view, examining defects from projects regardless of the engineers' purpose. Our study is focused on reengineering activities from a "process" view, and focuses on engineers specifically engaged in the reengineering process. Our goal is to understand the characteristics and challenges of deep learning model reengineering. We conducted a case study of this phenomenon, focusing on the context of computer vision. Our results draw from two data sources: defects reported in open-source reeengineering projects, and interviews conducted with open-source project contributors and the leaders of a reengineering team. Our results describe how deep learning-based computer vision techniques are reengineered, analyze the distribution of defects in this process, and discuss challenges and practices. Integrating our quantitative and qualitative data, we proposed a novel reengineering workflow. Our findings inform several future directions, including: measuring additional unknown aspects of model reengineering; standardizing engineering practices to facilitate reengineering; and developing tools to support model reengineering and model reuse.

Deep Learning has been one of the most disruptive technological advancements in recent times. The high performance of deep learning models comes at the expense of high computational, storage and power requirements. Sensing the immediate need for accelerating and compressing these models to improve on-device performance, we introduce Deeplite Neutrino for production-ready optimization of the models and Deeplite Runtime for deployment of ultra-low bit quantized models on Arm-based platforms. We implement low-level quantization kernels for Armv7 and Armv8 architectures enabling deployment on the vast array of 32-bit and 64-bit Arm-based devices. With efficient implementations using vectorization, parallelization, and tiling, we realize speedups of up to 2x and 2.2x compared to TensorFlow Lite with XNNPACK backend on classification and detection models, respectively. We also achieve significant speedups of up to 5x and 3.2x compared to ONNX Runtime for classification and detection models, respectively.

The aim of this work is to define a model based on deep learning that is able to identify different instrument timbres with as few parameters as possible. For this purpose, we have worked with classical orchestral instruments played with different dynamics, which are part of a few instrument families and which play notes in the same pitch range. It has been possible to assess the ability to classify instruments by timbre even if the instruments are playing the same note with the same intensity. The network employed uses a multi-head attention mechanism, with 8 heads and a dense network at the output taking as input the log-mel magnitude spectrograms of the sound samples. This network allows the identification of 20 instrument classes of the classical orchestra, achieving an overall F_1 value of 0.62. An analysis of the weights of the attention layer has been performed and the confusion matrix of the model is presented, allowing us to assess the ability of the proposed architecture to distinguish timbre and to establish the aspects on which future work should focus.

Designing robust systems for precise prediction of future prices of stocks has always been considered a very challenging research problem. Even more challenging is to build a system for constructing an optimum portfolio of stocks based on the forecasted future stock prices. We present a deep learning-based regression model built on a long-and-short-term memory network (LSTM) network that automatically scraps the web and extracts historical stock prices based on a stock's ticker name for a specified pair of start and end dates, and forecasts the future stock prices. We deploy the model on 75 significant stocks chosen from 15 critical sectors of the Indian stock market. For each of the stocks, the model is evaluated for its forecast accuracy. Moreover, the predicted values of the stock prices are used as the basis for investment decisions, and the returns on the investments are computed. Extensive results are presented on the performance of the model. The analysis of the results demonstrates the efficacy and effectiveness of the system and enables us to compare the profitability of the sectors from the point of view of the investors in the stock market.

Gastrointestinal (GI) diseases represent a significant global health concern, with Capsule Endoscopy (CE) offering a non-invasive method for diagnosis by capturing a large number of GI tract images. However, the sheer volume of video frames necessitates automated analysis to reduce the workload on doctors and increase the diagnostic accuracy. In this paper, we present CapsuleNet, a deep learning model developed for the Capsule Vision 2024 Challenge, aimed at classifying 10 distinct GI abnormalities. Using a highly imbalanced dataset, we implemented various data augmentation strategies, reducing the data imbalance to a manageable level. Our model leverages a pretrained EfficientNet-b7 backbone, tuned with additional layers for classification and optimized with PReLU activation functions. The model demonstrated superior performance on validation data, achieving a micro accuracy of 84.5% and outperforming the VGG16 baseline across most classes. Despite these advances, challenges remain in classifying certain abnormalities, such as Erythema. Our findings suggest that CNN-based models like CapsuleNet can provide an efficient solution for GI tract disease classification, particularly when inference time is a critical factor.

A key challenge for computationally intensive state-of-the-art Earth System models is to distinguish global warming signals from interannual variability. Here we introduce DLESyM, a parsimonious deep learning model that accurately simulates the Earth's current climate over 1000-year periods with no smoothing or drift. DLESyM simulations equal or exceed key metrics of seasonal and interannual variability--such as tropical cyclogenesis over the range of observed intensities, the cycle of the Indian Summer monsoon, and the climatology of mid-latitude blocking events--when compared to historical simulations from four leading models from the 6th Climate Model Intercomparison Project. DLESyM, trained on both historical reanalysis data and satellite observations, is an accurate, highly efficient model of the coupled Earth system, empowering long-range sub-seasonal and seasonal forecasts while using a fraction of the energy and computational time required by traditional models.

This research advances individual tree crown (ITC) segmentation in lidar data, using a deep learning model applicable to various laser scanning types: airborne (ULS), terrestrial (TLS), and mobile (MLS). It addresses the challenge of transferability across different data characteristics in 3D forest scene analysis. The study evaluates the model's performance based on platform (ULS, MLS) and data density, testing five scenarios with varying input data, including sparse versions, to gauge adaptability and canopy layer efficacy. The model, based on PointGroup architecture, is a 3D CNN with separate heads for semantic and instance segmentation, validated on diverse point cloud datasets. Results show point cloud sparsification enhances performance, aiding sparse data handling and improving detection in dense forests. The model performs well with >50 points per sq. m densities but less so at 10 points per sq. m due to higher omission rates. It outperforms existing methods (e.g., Point2Tree, TLS2trees) in detection, omission, commission rates, and F1 score, setting new benchmarks on LAUTx, Wytham Woods, and TreeLearn datasets. In conclusion, this study shows the feasibility of a sensor-agnostic model for diverse lidar data, surpassing sensor-specific approaches and setting new standards in tree segmentation, particularly in complex forests. This contributes to future ecological modeling and forest management advancements.

The presence of point defects such as vacancies plays an important role in material design. Here, we demonstrate that a graph neural network (GNN) model trained only on perfect materials can also be used to predict vacancy formation energies (E_{vac}) of defect structures without the need for additional training data. Such GNN-based predictions are considerably faster than density functional theory (DFT) calculations with reasonable accuracy and show the potential that GNNs are able to capture a functional form for energy predictions. To test this strategy, we developed a DFT dataset of 508 E_{vac} consisting of 3D elemental solids, alloys, oxides, nitrides, and 2D monolayer materials. We analyzed and discussed the applicability of such direct and fast predictions. We applied the model to predict 192494 E_{vac} for 55723 materials in the JARVIS-DFT database.

In recent years, Deep Learning (DL) models are becoming important due to their demonstrated success at overcoming complex learning problems. DL models have been applied effectively for different Natural Language Processing (NLP) tasks such as part-of-Speech (PoS) tagging and Machine Translation (MT). Disease Named Entity Recognition (Disease-NER) is a crucial task which aims at extracting disease Named Entities (NEs) from text. In this paper, a DL model for Disease-NER using dictionary information is proposed and evaluated on National Center for Biotechnology Information (NCBI) disease corpus and BC5CDR dataset. Word embeddings trained over general domain texts as well as biomedical texts have been used to represent input to the proposed model. This study also compares two different Segment Representation (SR) schemes, namely IOB2 and IOBES for Disease-NER. The results illustrate that using dictionary information, pre-trained word embeddings, character embeddings and CRF with global score improves the performance of Disease-NER system.

Existing deep learning models may encounter great challenges in handling graph structured data. In this paper, we introduce a new deep learning model for graph data specifically, namely the deep loopy neural network. Significantly different from the previous deep models, inside the deep loopy neural network, there exist a large number of loops created by the extensive connections among nodes in the input graph data, which makes model learning an infeasible task. To resolve such a problem, in this paper, we will introduce a new learning algorithm for the deep loopy neural network specifically. Instead of learning the model variables based on the original model, in the proposed learning algorithm, errors will be back-propagated through the edges in a group of extracted spanning trees. Extensive numerical experiments have been done on several real-world graph datasets, and the experimental results demonstrate the effectiveness of both the proposed model and the learning algorithm in handling graph data.

Multi-omics research has enhanced our understanding of cancer heterogeneity and progression. Investigating molecular data through multi-omics approaches is crucial for unraveling the complex biological mechanisms underlying cancer, thereby enabling effective diagnosis, treatment, and prevention strategies. However, predicting patient outcomes through integration of all available multi-omics data is an under-study research direction. Here, we present SeNMo (Self-normalizing Network for Multi-omics), a deep neural network trained on multi-omics data across 33 cancer types. SeNMo is efficient in handling multi-omics data characterized by high-width (many features) and low-length (fewer samples) attributes. We trained SeNMo for the task of overall survival using pan-cancer data involving 33 cancer sites from Genomics Data Commons (GDC). The training data includes gene expression, DNA methylation, miRNA expression, DNA mutations, protein expression modalities, and clinical data. We evaluated the model's performance in predicting overall survival using concordance index (C-Index). SeNMo performed consistently well in training regime, with the validation C-Index of 0.76 on GDC's public data. In the testing regime, SeNMo performed with a C-Index of 0.758 on a held-out test set. The model showed an average accuracy of 99.8% on the task of classifying the primary cancer type on the pan-cancer test cohort. SeNMo proved to be a mini-foundation model for multi-omics oncology data because it demonstrated robust performance, and adaptability not only across molecular data types but also on the classification task of predicting the primary cancer type of patients. SeNMo can be further scaled to any cancer site and molecular data type. We believe SeNMo and similar models are poised to transform the oncology landscape, offering hope for more effective, efficient, and patient-centric cancer care.

The size and frequency of wildland fires in the western United States have dramatically increased in recent years. On high-fire-risk days, a small fire ignition can rapidly grow and become out of control. Early detection of fire ignitions from initial smoke can assist the response to such fires before they become difficult to manage. Past deep learning approaches for wildfire smoke detection have suffered from small or unreliable datasets that make it difficult to extrapolate performance to real-world scenarios. In this work, we present the Fire Ignition Library (FIgLib), a publicly available dataset of nearly 25,000 labeled wildfire smoke images as seen from fixed-view cameras deployed in Southern California. We also introduce SmokeyNet, a novel deep learning architecture using spatiotemporal information from camera imagery for real-time wildfire smoke detection. When trained on the FIgLib dataset, SmokeyNet outperforms comparable baselines and rivals human performance. We hope that the availability of the FIgLib dataset and the SmokeyNet architecture will inspire further research into deep learning methods for wildfire smoke detection, leading to automated notification systems that reduce the time to wildfire response.

Channel state information (CSI) prediction is a promising strategy for ensuring reliable and efficient operation of massive multiple-input multiple-output (mMIMO) systems by providing timely downlink (DL) CSI. While deep learning-based methods have advanced beyond conventional model-driven and statistical approaches, they remain limited in robustness to practical non-Gaussian noise, generalization across diverse channel conditions, and computational efficiency. This paper introduces CSI-4CAST, a hybrid deep learning architecture that integrates 4 key components, i.e., Convolutional neural network residuals, Adaptive correction layers, ShuffleNet blocks, and Transformers, to efficiently capture both local and long-range dependencies in CSI prediction. To enable rigorous evaluation, this work further presents a comprehensive benchmark, CSI-RRG for Regular, Robustness and Generalization testing, which includes more than 300,000 samples across 3,060 realistic scenarios for both TDD and FDD systems. The dataset spans multiple channel models, a wide range of delay spreads and user velocities, and diverse noise types and intensity degrees. Experimental results show that CSI-4CAST achieves superior prediction accuracy with substantially lower computational cost, outperforming baselines in 88.9% of TDD scenarios and 43.8% of FDD scenario, the best performance among all evaluated models, while reducing FLOPs by 5x and 3x compared to LLM4CP, the strongest baseline. In addition, evaluation over CSI-RRG provides valuable insights into how different channel factors affect the performance and generalization capability of deep learning models. Both the dataset (https://huggingface.co/CSI-4CAST) and evaluation protocols (https://github.com/AI4OPT/CSI-4CAST) are publicly released to establish a standardized benchmark and to encourage further research on robust and efficient CSI prediction.

Deep learning has advanced mass spectrometry data interpretation, yet most models remain feature extractors rather than unified scoring frameworks. We present pUniFind, the first large-scale multimodal pre-trained model in proteomics that integrates end-to-end peptide-spectrum scoring with open, zero-shot de novo sequencing. Trained on over 100 million open search-derived spectra, pUniFind aligns spectral and peptide modalities via cross modality prediction and outperforms traditional engines across diverse datasets, particularly achieving a 42.6 percent increase in the number of identified peptides in immunopeptidomics. Supporting over 1,300 modifications, pUniFind identifies 60 percent more PSMs than existing de novo methods despite a 300-fold larger search space. A deep learning based quality control module further recovers 38.5 percent additional peptides including 1,891 mapped to the genome but absent from reference proteomes while preserving full fragment ion coverage. These results establish a unified, scalable deep learning framework for proteomic analysis, offering improved sensitivity, modification coverage, and interpretability.

Radar-based contactless cardiac monitoring has become a popular research direction recently, but the fine-grained electrocardiogram (ECG) signal is still hard to reconstruct from millimeter-wave radar signal. The key obstacle is to decouple the cardiac activities in the electrical domain (i.e., ECG) from that in the mechanical domain (i.e., heartbeat), and most existing research only uses pure data-driven methods to map such domain transformation as a black box. Therefore, this work first proposes a signal model for domain transformation, and then a novel deep learning framework called radarODE is designed to fuse the temporal and morphological features extracted from radar signals and generate ECG. In addition, ordinary differential equations are embedded in radarODE as a decoder to provide morphological prior, helping the convergence of the model training and improving the robustness under body movements. After being validated on the dataset, the proposed radarODE achieves better performance compared with the benchmark in terms of missed detection rate, root mean square error, Pearson correlation coefficient with the improvement of 9%, 16% and 19%, respectively. The validation results imply that radarODE is capable of recovering ECG signals from radar signals with high fidelity and can be potentially implemented in real-life scenarios.

In this paper, we present a lightweight and effective change detection model, called TinyCD. This model has been designed to be faster and smaller than current state-of-the-art change detection models due to industrial needs. Despite being from 13 to 140 times smaller than the compared change detection models, and exposing at least a third of the computational complexity, our model outperforms the current state-of-the-art models by at least 1% on both F1 score and IoU on the LEVIR-CD dataset, and more than 8% on the WHU-CD dataset. To reach these results, TinyCD uses a Siamese U-Net architecture exploiting low-level features in a globally temporal and locally spatial way. In addition, it adopts a new strategy to mix features in the space-time domain both to merge the embeddings obtained from the Siamese backbones, and, coupled with an MLP block, it forms a novel space-semantic attention mechanism, the Mix and Attention Mask Block (MAMB). Source code, models and results are available here: https://github.com/AndreaCodegoni/Tiny_model_4_CD

Photoplethysmography (PPG) signals, which measure changes in blood volume in the skin using light, have recently gained attention in biometric authentication because of their non-invasive acquisition, inherent liveness detection, and suitability for low-cost wearable devices. However, PPG signal quality is challenged by motion artifacts, illumination changes, and inter-subject physiological variability, making robust feature extraction and classification crucial. This study proposes a lightweight and cost-effective biometric authentication framework based on PPG signals extracted from low-frame-rate fingertip videos. The CFIHSR dataset, comprising PPG recordings from 46 subjects at a sampling rate of 14 Hz, is employed for evaluation. The raw PPG signals undergo a standard preprocessing pipeline involving baseline drift removal, motion artifact suppression using Principal Component Analysis (PCA), bandpass filtering, Fourier-based resampling, and amplitude normalization. To generate robust representations, each one-dimensional PPG segment is converted into a two-dimensional time-frequency scalogram via the Continuous Wavelet Transform (CWT), effectively capturing transient cardiovascular dynamics. We developed a hybrid deep learning model, termed CVT-ConvMixer-LSTM, by combining spatial features from the Convolutional Vision Transformer (CVT) and ConvMixer branches with temporal features from a Long Short-Term Memory network (LSTM). The experimental results on 46 subjects demonstrate an authentication accuracy of 98%, validating the robustness of the model to noise and variability between subjects. Due to its efficiency, scalability, and inherent liveness detection capability, the proposed system is well-suited for real-world mobile and embedded biometric security applications.

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel, cell-type-specialised decoders. Through multi-task learning, each decoder jointly predicts nuclei centroids, segmentation masks, and contours, aided by Spatial and Channel Squeeze-and-Excitation (SCSE) attention modules and a composite loss function. We validate KongNet in three Grand Challenges. The proposed model achieved first place on track 1 and second place on track 2 during the MONKEY Challenge. Its lightweight variant (KongNet-Det) secured first place in the 2025 MIDOG Challenge. KongNet pre-trained on the MONKEY dataset and fine-tuned on the PUMA dataset ranked among the top three in the PUMA Challenge without further optimisation. Furthermore, KongNet established state-of-the-art performance on the publicly available PanNuke and CoNIC datasets. Our results demonstrate that the specialised multi-decoder design is highly effective for nuclei detection and classification across diverse tissue and stain types. The pre-trained model weights along with the inference code have been publicly released to support future research.

Accurate and fast prediction of materials properties is central to the digital transformation of materials design. However, the vast design space and diverse operating conditions pose significant challenges for accurately modeling arbitrary material candidates and forecasting their properties. We present MatterSim, a deep learning model actively learned from large-scale first-principles computations, for efficient atomistic simulations at first-principles level and accurate prediction of broad material properties across the periodic table, spanning temperatures from 0 to 5000 K and pressures up to 1000 GPa. Out-of-the-box, the model serves as a machine learning force field, and shows remarkable capabilities not only in predicting ground-state material structures and energetics, but also in simulating their behavior under realistic temperatures and pressures, signifying an up to ten-fold enhancement in precision compared to the prior best-in-class. This enables MatterSim to compute materials' lattice dynamics, mechanical and thermodynamic properties, and beyond, to an accuracy comparable with first-principles methods. Specifically, MatterSim predicts Gibbs free energies for a wide range of inorganic solids with near-first-principles accuracy and achieves a 15 meV/atom resolution for temperatures up to 1000K compared with experiments. This opens an opportunity to predict experimental phase diagrams of materials at minimal computational cost. Moreover, MatterSim also serves as a platform for continuous learning and customization by integrating domain-specific data. The model can be fine-tuned for atomistic simulations at a desired level of theory or for direct structure-to-property predictions, achieving high data efficiency with a reduction in data requirements by up to 97%.

PURPOSE: Subarachnoid hemorrhage (SAH) entails high morbidity and mortality rates. Convolutional neural networks (CNN), a form of deep learning, are capable of generating highly accurate predictions from imaging data. Our objective was to predict mortality in SAH patients by processing the initial CT scan on a CNN based algorithm. METHODS: Retrospective multicentric study of a consecutive cohort of patients with SAH between 2011-2022. Demographic, clinical and radiological variables were analyzed. Pre-processed baseline CT scan images were used as the input for training a CNN using AUCMEDI Framework. Our model's architecture leverages the DenseNet-121 structure, employing transfer learning principles. The output variable was mortality in the first three months. Performance of the model was evaluated by statistical parameters conventionally used in studies involving artificial intelligence methods. RESULTS: Images from 219 patients were processed, 175 for training and validation of the CNN and 44 for its evaluation. 52%(115/219) of patients were female, and the median age was 58(SD=13.06) years. 18.5%(39/219) were idiopathic SAH. Mortality rate was 28.5%(63/219). The model showed good accuracy at predicting mortality in SAH patients exclusively using the images of the initial CT scan (Accuracy=74%, F1=75% and AUC=82%). CONCLUSION: Modern image processing techniques based on AI and CNN make possible to predict mortality in SAH patients with high accuracy using CT scan images as the only input. These models might be optimized by including more data and patients resulting in better training, development and performance on tasks which are beyond the skills of conventional clinical knowledge.

Analyzing both temporal and spatial patterns for an accurate forecasting model for financial time series forecasting is a challenge due to the complex nature of temporal-spatial dynamics: time series from different locations often have distinct patterns; and for the same time series, patterns may vary as time goes by. Inspired by the successful applications of deep learning, we propose a new model to resolve the issues of forecasting household leverage in China. Our solution consists of multiple RNN-based layers and an attention layer: each RNN-based layer automatically learns the temporal pattern of a specific series with multivariate exogenous series, and then the attention layer learns the spatial correlative weight and obtains the global representations simultaneously. The results show that the new approach can capture the temporal-spatial dynamics of household leverage well and get more accurate and solid predictive results. More, the simulation also studies show that clustering and choosing correlative series are necessary to obtain accurate forecasting results.

In this paper, a 3D-RegNet-based neural network is proposed for diagnosing the physical condition of patients with coronavirus (Covid-19) infection. In the application of clinical medicine, lung CT images are utilized by practitioners to determine whether a patient is infected with coronavirus. However, there are some laybacks can be considered regarding to this diagnostic method, such as time consuming and low accuracy. As a relatively large organ of human body, important spatial features would be lost if the lungs were diagnosed utilizing two dimensional slice image. Therefore, in this paper, a deep learning model with 3D image was designed. The 3D image as input data was comprised of two-dimensional pulmonary image sequence and from which relevant coronavirus infection 3D features were extracted and classified. The results show that the test set of the 3D model, the result: f1 score of 0.8379 and AUC value of 0.8807 have been achieved.

Dynamic imaging is a beneficial tool for interventions to assess physiological changes. Nonetheless during dynamic MRI, while achieving a high temporal resolution, the spatial resolution is compromised. To overcome this spatio-temporal trade-off, this research presents a super-resolution (SR) MRI reconstruction with prior knowledge based fine-tuning to maximise spatial information while reducing the required scan-time for dynamic MRIs. An U-Net based network with perceptual loss is trained on a benchmark dataset and fine-tuned using one subject-specific static high resolution MRI as prior knowledge to obtain high resolution dynamic images during the inference stage. 3D dynamic data for three subjects were acquired with different parameters to test the generalisation capabilities of the network. The method was tested for different levels of in-plane undersampling for dynamic MRI. The reconstructed dynamic SR results after fine-tuning showed higher similarity with the high resolution ground-truth, while quantitatively achieving statistically significant improvement. The average SSIM of the lowest resolution experimented during this research (6.25~\% of the k-space) before and after fine-tuning were 0.939 pm 0.008 and 0.957 pm 0.006 respectively. This could theoretically result in an acceleration factor of 16, which can potentially be acquired in less than half a second. The proposed approach shows that the super-resolution MRI reconstruction with prior-information can alleviate the spatio-temporal trade-off in dynamic MRI, even for high acceleration factors.

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to variability, motivating the use of deep learning to improve consistency and alleviate clinical workload. However, existing methods often fail to fully exploit the information available in multi-parametric MRI (mp-MRI), particularly inter-slice contextual features, and typically require considerable computational resources while lacking robustness across tumor type variations. We present GBT-SAM, a parameter-efficient deep learning framework that adapts the Segment Anything Model (SAM), a large-scale vision model, to volumetric mp-MRI data. GBT-SAM reduces input complexity by selecting fewer than 2.6\% of slices per scan while incorporating all four MRI modalities, preserving essential tumor-related information with minimal cost. Furthermore, our model is trained by a two-step fine-tuning strategy that incorporates a depth-aware module to capture inter-slice correlations and lightweight adaptation layers, resulting in just 6.5M trainable parameters, which is the lowest among SAM-based approaches. GBT-SAM achieves a Dice Score of 93.54 on the BraTS Adult Glioma dataset and demonstrates robust performance on Meningioma, Pediatric Glioma, and Sub-Saharan Glioma datasets. These results highlight GBT-SAM's potential as a computationally efficient and domain-robust framework for brain tumor segmentation using mp-MRI. Our code and models are available at https://github.com/vpulab/med-sam-brain .

A ventilator simulation system can make mechanical ventilation easier and more effective. As a result, predicting a patient's ventilator pressure is essential when designing a simulation ventilator. We suggested a hybrid deep learning-based approach to forecast required ventilator pressure for patients. This system is made up of Bi-LSTM and Bi-GRU networks. The SELU activation function was used in our proposed model. MAE and MSE were used to examine the accuracy of the proposed model so that our proposed methodology can be applied to real-world problems. The model performed well against test data and created far too few losses. Major parts of our research were data collection, data analysis, data cleaning, building hybrid Bi-LSTM and Bi-GRU model, training the model, model evaluation, and result analysis. We compared the results of our research with some contemporary works, and our proposed model performed better than those models.

The COVID-19 pandemic has spread globally for several months. Because its transmissibility and high pathogenicity seriously threaten people's lives, it is crucial to accurately and quickly detect COVID-19 infection. Many recent studies have shown that deep learning (DL) based solutions can help detect COVID-19 based on chest CT scans. However, most existing work focuses on 2D datasets, which may result in low quality models as the real CT scans are 3D images. Besides, the reported results span a broad spectrum on different datasets with a relatively unfair comparison. In this paper, we first use three state-of-the-art 3D models (ResNet3D101, DenseNet3D121, and MC3\_18) to establish the baseline performance on the three publicly available chest CT scan datasets. Then we propose a differentiable neural architecture search (DNAS) framework to automatically search for the 3D DL models for 3D chest CT scans classification with the Gumbel Softmax technique to improve the searching efficiency. We further exploit the Class Activation Mapping (CAM) technique on our models to provide the interpretability of the results. The experimental results show that our automatically searched models (CovidNet3D) outperform the baseline human-designed models on the three datasets with tens of times smaller model size and higher accuracy. Furthermore, the results also verify that CAM can be well applied in CovidNet3D for COVID-19 datasets to provide interpretability for medical diagnosis.

Background: Pancreatic cancer is one of the most aggressive cancers, with poor survival rates. Endoscopic ultrasound (EUS) is a key diagnostic modality, but its effectiveness is constrained by operator subjectivity. This study evaluates a Vision Transformer-based deep learning segmentation model for pancreatic tumors. Methods: A segmentation model using the USFM framework with a Vision Transformer backbone was trained and validated with 17,367 EUS images (from two public datasets) in 5-fold cross-validation. The model was tested on an independent dataset of 350 EUS images from another public dataset, manually segmented by radiologists. Preprocessing included grayscale conversion, cropping, and resizing to 512x512 pixels. Metrics included Dice similarity coefficient (DSC), intersection over union (IoU), sensitivity, specificity, and accuracy. Results: In 5-fold cross-validation, the model achieved a mean DSC of 0.651 +/- 0.738, IoU of 0.579 +/- 0.658, sensitivity of 69.8%, specificity of 98.8%, and accuracy of 97.5%. For the external validation set, the model achieved a DSC of 0.657 (95% CI: 0.634-0.769), IoU of 0.614 (95% CI: 0.590-0.689), sensitivity of 71.8%, and specificity of 97.7%. Results were consistent, but 9.7% of cases exhibited erroneous multiple predictions. Conclusions: The Vision Transformer-based model demonstrated strong performance for pancreatic tumor segmentation in EUS images. However, dataset heterogeneity and limited external validation highlight the need for further refinement, standardization, and prospective studies.

The rapid growth of AI has led to more complex deep learning models, often operating as opaque "black boxes" with limited transparency in their decision-making. This lack of interpretability poses challenges, especially in high-stakes applications where understanding model output is crucial. This work highlights the importance of interpretability in fostering trust, accountability, and responsible deployment. To address these challenges, we introduce DLBacktrace, a novel, model-agnostic technique designed to provide clear insights into deep learning model decisions across a wide range of domains and architectures, including MLPs, CNNs, and Transformer-based LLM models. We present a comprehensive overview of DLBacktrace and benchmark its performance against established interpretability methods such as SHAP, LIME, and GradCAM. Our results demonstrate that DLBacktrace effectively enhances understanding of model behavior across diverse tasks. DLBacktrace is compatible with models developed in both PyTorch and TensorFlow, supporting architectures such as BERT, ResNet, U-Net, and custom DNNs for tabular data. The library is open-sourced and available at https://github.com/AryaXAI/DLBacktrace .

With the growing applications of Deep Learning (DL), especially recent spectacular achievements of Large Language Models (LLMs) such as ChatGPT and LLaMA, the commercial significance of these remarkable models has soared. However, acquiring well-trained models is costly and resource-intensive. It requires a considerable high-quality dataset, substantial investment in dedicated architecture design, expensive computational resources, and efforts to develop technical expertise. Consequently, safeguarding the Intellectual Property (IP) of well-trained models is attracting increasing attention. In contrast to existing surveys overwhelmingly focusing on model IPP mainly, this survey not only encompasses the protection on model level intelligence but also valuable dataset intelligence. Firstly, according to the requirements for effective IPP design, this work systematically summarizes the general and scheme-specific performance evaluation metrics. Secondly, from proactive IP infringement prevention and reactive IP ownership verification perspectives, it comprehensively investigates and analyzes the existing IPP methods for both dataset and model intelligence. Additionally, from the standpoint of training settings, it delves into the unique challenges that distributed settings pose to IPP compared to centralized settings. Furthermore, this work examines various attacks faced by deep IPP techniques. Finally, we outline prospects for promising future directions that may act as a guide for innovative research.

While computer science has seen remarkable advancements in foundation models, which remain underexplored in geoscience. Addressing this gap, we introduce a workflow to develop geophysical foundation models, including data preparation, model pre-training, and adaption to downstream tasks. From 192 globally collected 3-D seismic volumes, we create a carefully curated dataset of 2,286,422 2-D seismic images. Fully using these unlabeled images, we employ the self-supervised learning to pre-train a Transformer-based Seismic Foundation Model (SFM) for producing all-purpose seismic features that work across various tasks and surveys. Through experiments on seismic facies classification, geobody identification, interpolation, denoising, and inversion, our pre-trained model demonstrates versatility, generalization, scalability, and superior performance over baseline models. Conclusively, we provide a foundation model and vast dataset to advance AI in geophysics, addressing challenges (poor generalization, lacking labels, and repetitive training for task-specified models) of applying AI in geophysics and paving the way for future innovations in geoscience.

Deep Neural Networks (DNNs) are being adopted as components in software systems. Creating and specializing DNNs from scratch has grown increasingly difficult as state-of-the-art architectures grow more complex. Following the path of traditional software engineering, machine learning engineers have begun to reuse large-scale pre-trained models (PTMs) and fine-tune these models for downstream tasks. Prior works have studied reuse practices for traditional software packages to guide software engineers towards better package maintenance and dependency management. We lack a similar foundation of knowledge to guide behaviors in pre-trained model ecosystems. In this work, we present the first empirical investigation of PTM reuse. We interviewed 12 practitioners from the most popular PTM ecosystem, Hugging Face, to learn the practices and challenges of PTM reuse. From this data, we model the decision-making process for PTM reuse. Based on the identified practices, we describe useful attributes for model reuse, including provenance, reproducibility, and portability. Three challenges for PTM reuse are missing attributes, discrepancies between claimed and actual performance, and model risks. We substantiate these identified challenges with systematic measurements in the Hugging Face ecosystem. Our work informs future directions on optimizing deep learning ecosystems by automated measuring useful attributes and potential attacks, and envision future research on infrastructure and standardization for model registries.

Heterogeneous unmanned aerial vehicle (UAV) swarms consist of dozens to hundreds of drones with different roles and varying hardware and software requirements collaborating towards a shared mission. While traditional approaches for synchronized software updates assume swarms to be unstructured and homogeneous, the heterogeneous nature of modern swarms and the emerging need of drones to update their deep learning (perception) models with new objectives or data as a mission unfolds, has made efficient software update methods crucial for swarms to adapt to dynamic environments. To address these challenges, we introduce the SwarmUpdate framework for software updates in heterogeneous UAV swarms, composed of two key components: SwarmSync and SwarmModelPatch. SwarmSync is a hierarchical software update synchronization strategy to distribute a software update to the right subset of drones within a swarm, while SwarmModelPatch is a deep learning model patching method that reduces the size of a (deep learning model) update by only allowing some layers of the model to be updated (freezing the other layers). In this paper, we systematically evaluate the performance of SwarmSync through large-scale simulations in the ARGoS swarm simulator, comparing SwarmSync to auction-based (SOUL) and gossip-based rebroadcasting (Gossip) baselines, and SwarmModelPatch to a non-incremental model patching strategy.

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image datasets, where certain tumor subtypes may appear much less frequently. This constitutes a considerable limitation in biased model predictions that can overlook critical but rare classes. In this work, we adopted EfficientNet, a state-of-the-art convolutional neural network (CNN) model that balances high accuracy with computational cost efficiency. To address data imbalance, we introduce an intensive data augmentation pipeline and cost-sensitive learning, improving representation and ensuring that the model does not overly favor majority classes. This approach provides the ability to learn effectively from rare tumor types, improving its robustness. Additionally, we fine-tuned the model using transfer learning, where weights in the beginning trained on a binary classification task were adopted to multi-class classification, improving the capability to detect complex patterns within the BreakHis dataset. Our results underscore significant improvements in the binary classification performance, achieving an exceptional recall increase for benign cases from 0.92 to 0.95, alongside an accuracy enhancement from 97.35 % to 98.23%. Our approach improved the performance of multi-class tasks from 91.27% with regular augmentation to 94.54% with intensive augmentation, reaching 95.04% with transfer learning. This framework demonstrated substantial gains in precision in the minority classes, such as Mucinous carcinoma and Papillary carcinoma, while maintaining high recall consistently across these critical subtypes, as further confirmed by confusion matrix analysis.

Fluorescence Lifetime Imaging (FLI) is a critical molecular imaging modality that provides unique information about the tissue microenvironment, which is invaluable for biomedical applications. FLI operates by acquiring and analyzing photon time-of-arrival histograms to extract quantitative parameters associated with temporal fluorescence decay. These histograms are influenced by the intrinsic properties of the fluorophore, instrument parameters, time-of-flight distributions associated with pixel-wise variations in the topographic and optical characteristics of the sample. Recent advancements in Deep Learning (DL) have enabled improved fluorescence lifetime parameter estimation. However, existing models are primarily designed for planar surface samples, limiting their applicability in translational scenarios involving complex surface profiles, such as in-vivo whole-animal or imaged guided surgical applications. To address this limitation, we present MFliNet (Macroscopic FLI Network), a novel DL architecture that integrates the Instrument Response Function (IRF) as an additional input alongside experimental photon time-of-arrival histograms. Leveraging the capabilities of a Differential Transformer encoder-decoder architecture, MFliNet effectively focuses on critical input features, such as variations in photon time-of-arrival distributions. We evaluate MFliNet using rigorously designed tissue-mimicking phantoms and preclinical in-vivo cancer xenograft models. Our results demonstrate the model's robustness and suitability for complex macroscopic FLI applications, offering new opportunities for advanced biomedical imaging in diverse and challenging settings.

Software engineers develop, fine-tune, and deploy deep learning (DL) models. They use and re-use models in a variety of development frameworks and deploy them on a range of runtime environments. In this diverse ecosystem, engineers use DL model converters to move models from frameworks to runtime environments. However, errors in converters can compromise model quality and disrupt deployment. The failure frequency and failure modes of DL model converters are unknown. In this paper, we conduct the first failure analysis on DL model converters. Specifically, we characterize failures in model converters associated with ONNX (Open Neural Network eXchange). We analyze past failures in the ONNX converters in two major DL frameworks, PyTorch and TensorFlow. The symptoms, causes, and locations of failures (for N=200 issues), and trends over time are also reported. We also evaluate present-day failures by converting 8,797 models, both real-world and synthetically generated instances. The consistent result from both parts of the study is that DL model converters commonly fail by producing models that exhibit incorrect behavior: 33% of past failures and 8% of converted models fell into this category. Our results motivate future research on making DL software simpler to maintain, extend, and validate.

Reading and interpreting chest X-ray images is one of the most radiologist's routines. However, it still can be challenging, even for the most experienced ones. Therefore, we proposed a multi-model deep learning-based automated chest X-ray report generator system designed to assist radiologists in their work. The basic idea of the proposed system is by utilizing multi binary-classification models for detecting multi abnormalities, with each model responsible for detecting one abnormality, in a single image. In this study, we limited the radiology abnormalities detection to only cardiomegaly, lung effusion, and consolidation. The system generates a radiology report by performing the following three steps: image pre-processing, utilizing deep learning models to detect abnormalities, and producing a report. The aim of the image pre-processing step is to standardize the input by scaling it to 128x128 pixels and slicing it into three segments, which covers the upper, lower, and middle parts of the lung. After pre-processing, each corresponding model classifies the image, resulting in a 0 (zero) for no abnormality detected and a 1 (one) for the presence of an abnormality. The prediction outputs of each model are then concatenated to form a 'result code'. The 'result code' is used to construct a report by selecting the appropriate pre-determined sentence for each detected abnormality in the report generation step. The proposed system is expected to reduce the workload of radiologists and increase the accuracy of chest X-ray diagnosis.

There will be a paradigm shift in chemical and biological research, to be enabled by autonomous, closed-loop, real-time self-directed decision-making experimentation. Spectrum-to-structure correlation, which is to elucidate molecular structures with spectral information, is the core step in understanding the experimental results and to close the loop. However, current approaches usually divide the task into either database-dependent retrieval and database-independent generation and neglect the inherent complementarity between them. In this study, we proposed Vib2Mol, a general deep learning model designed to flexibly handle diverse spectrum-to-structure tasks according to the available prior knowledge by bridging the retrieval and generation. It achieves state-of-the-art performance, even for the most demanding Raman spectra, over previous models in predicting reaction products and sequencing peptides as well as analyzing experimental spectra and integrating multi-modal spectral data. Vib2Mol enables vibrational spectroscopy a real-time guide for autonomous scientific discovery workflows.

Currently, deep learning-based instance segmentation for various applications (e.g., Agriculture) is predominantly performed using a labor-intensive process involving extensive field data collection using sophisticated sensors, followed by careful manual annotation of images, presenting significant logistical and financial challenges to researchers and organizations. The process also slows down the model development and training process. In this study, we presented a novel method for deep learning-based instance segmentation of apples in commercial orchards that eliminates the need for labor-intensive field data collection and manual annotation. Utilizing a Large Language Model (LLM), we synthetically generated orchard images and automatically annotated them using the Segment Anything Model (SAM) integrated with a YOLO11 base model. This method significantly reduces reliance on physical sensors and manual data processing, presenting a major advancement in "Agricultural AI". The synthetic, auto-annotated dataset was used to train the YOLO11 model for Apple instance segmentation, which was then validated on real orchard images. The results showed that the automatically generated annotations achieved a Dice Coefficient of 0.9513 and an IoU of 0.9303, validating the accuracy and overlap of the mask annotations. All YOLO11 configurations, trained solely on these synthetic datasets with automated annotations, accurately recognized and delineated apples, highlighting the method's efficacy. Specifically, the YOLO11m-seg configuration achieved a mask precision of 0.902 and a mask mAP@50 of 0.833 on test images collected from a commercial orchard. Additionally, the YOLO11l-seg configuration outperformed other models in validation on 40 LLM-generated images, achieving the highest mask precision and mAP@50 metrics. Keywords: YOLO, SAM, SAMv2, YOLO11, YOLOv11, Segment Anything, YOLO-SAM

Biodiversity assessments are critically affected by the spatial scale at which species richness is measured. How species richness accumulates with sampling area depends on natural and anthropogenic processes whose effects can change depending on the spatial scale considered. These accumulation dynamics, described by the species-area relationship (SAR), are challenging to assess because most biodiversity surveys are restricted to sampling areas much smaller than the scales at which these processes operate. Here, we combine sampling theory and deep learning to predict local species richness within arbitrarily large sampling areas, enabling for the first time to estimate spatial differences in SARs. We demonstrate our approach by predicting vascular plant species richness across Europe and evaluate predictions against an independent dataset of plant community inventories. The resulting model, named deep SAR, delivers multi-scale species richness maps, improving coarse grain richness estimates by 32% compared to conventional methods, while delivering finer grain estimates. Additional to its predictive capabilities, we show how our deep SAR model can provide fundamental insights on the multi-scale effects of key biodiversity processes. The capacity of our approach to deliver comprehensive species richness estimates across the full spectrum of ecologically relevant scales is essential for robust biodiversity assessments and forecasts under global change.

Human mobility plays a crucial role in transportation, urban planning, and public health. Advances in deep learning and the availability of diverse mobility data have transformed mobility modeling. However, existing deep learning models often focus on spatio-temporal patterns and struggle to capture the semantic interdependencies among activities, while also being limited by specific data sources. These challenges reduce their realism and adaptability. Traditional activity-based models (ABMs) face issues as well, relying on rigid assumptions and requiring extensive data, making them costly and difficult to adapt to new regions, especially those with limited conventional travel data. To address these limitations, we develop a novel generative deep learning approach for human mobility modeling and synthesis that incorporates both activity patterns and location trajectories using open-source data. The model can be fine-tuned with local data, allowing it to adapt to and accurately represent mobility patterns across diverse regions. The model is evaluated on a nationwide dataset of the United States, where it demonstrates superior performance in generating activity-location chains that closely follow ground truth distributions. Further tests using state- or city-specific datasets from California, Washington, and Mexico City confirm its transferability. This innovative approach offers substantial potential to advance mobility modeling research, particularly in generating synthetic human mobility data. This can provide urban planners and policymakers with enhanced tools for simulating mobility in diverse regions and better informing decisions related to transportation, urban development, and public health.

Purpose: To evaluate the performance of an automated deep learning method in detecting ascites and subsequently quantifying its volume in patients with liver cirrhosis and ovarian cancer. Materials and Methods: This retrospective study included contrast-enhanced and non-contrast abdominal-pelvic CT scans of patients with cirrhotic ascites and patients with ovarian cancer from two institutions, National Institutes of Health (NIH) and University of Wisconsin (UofW). The model, trained on The Cancer Genome Atlas Ovarian Cancer dataset (mean age, 60 years +/- 11 [s.d.]; 143 female), was tested on two internal (NIH-LC and NIH-OV) and one external dataset (UofW-LC). Its performance was measured by the Dice coefficient, standard deviations, and 95% confidence intervals, focusing on ascites volume in the peritoneal cavity. Results: On NIH-LC (25 patients; mean age, 59 years +/- 14 [s.d.]; 14 male) and NIH-OV (166 patients; mean age, 65 years +/- 9 [s.d.]; all female), the model achieved Dice scores of 0.855 +/- 0.061 (CI: 0.831-0.878) and 0.826 +/- 0.153 (CI: 0.764-0.887), with median volume estimation errors of 19.6% (IQR: 13.2-29.0) and 5.3% (IQR: 2.4-9.7) respectively. On UofW-LC (124 patients; mean age, 46 years +/- 12 [s.d.]; 73 female), the model had a Dice score of 0.830 +/- 0.107 (CI: 0.798-0.863) and median volume estimation error of 9.7% (IQR: 4.5-15.1). The model showed strong agreement with expert assessments, with r^2 values of 0.79, 0.98, and 0.97 across the test sets. Conclusion: The proposed deep learning method performed well in segmenting and quantifying the volume of ascites in concordance with expert radiologist assessments.

We present the first deep learning model for segmenting galactic spiral arms and bars. In a blinded assessment by expert astronomers, our predicted spiral arm masks are preferred over both current automated methods (99% of evaluations) and our original volunteer labels (79% of evaluations). Experts rated our spiral arm masks as `mostly good' to `perfect' in 89% of evaluations. Bar lengths trivially derived from our predicted bar masks are in excellent agreement with a dedicated crowdsourcing project. The pixelwise precision of our masks, previously impossible at scale, will underpin new research into how spiral arms and bars evolve.

Insect-pests significantly impact global agricultural productivity and quality. Effective management involves identifying the full insect community, including beneficial insects and harmful pests, to develop and implement integrated pest management strategies. Automated identification of insects under real-world conditions presents several challenges, including differentiating similar-looking species, intra-species dissimilarity and inter-species similarity, several life cycle stages, camouflage, diverse imaging conditions, and variability in insect orientation. A deep-learning model, InsectNet, is proposed to address these challenges. InsectNet is endowed with five key features: (a) utilization of a large dataset of insect images collected through citizen science; (b) label-free self-supervised learning for large models; (c) improving prediction accuracy for species with a small sample size; (d) enhancing model trustworthiness; and (e) democratizing access through streamlined MLOps. This approach allows accurate identification (>96% accuracy) of over 2500 insect species, including pollinator (e.g., butterflies, bees), parasitoid (e.g., some wasps and flies), predator species (e.g., lady beetles, mantises, dragonflies) and harmful pest species (e.g., armyworms, cutworms, grasshoppers, stink bugs). InsectNet can identify invasive species, provide fine-grained insect species identification, and work effectively in challenging backgrounds. It also can abstain from making predictions when uncertain, facilitating seamless human intervention and making it a practical and trustworthy tool. InsectNet can guide citizen science data collection, especially for invasive species where early detection is crucial. Similar approaches may transform other agricultural challenges like disease detection and underscore the importance of data collection, particularly through citizen science efforts..

With recent developments in deep learning, the ubiquity of micro-phones and the rise in online services via personal devices, acoustic side channel attacks present a greater threat to keyboards than ever. This paper presents a practical implementation of a state-of-the-art deep learning model in order to classify laptop keystrokes, using a smartphone integrated microphone. When trained on keystrokes recorded by a nearby phone, the classifier achieved an accuracy of 95%, the highest accuracy seen without the use of a language model. When trained on keystrokes recorded using the video-conferencing software Zoom, an accuracy of 93% was achieved, a new best for the medium. Our results prove the practicality of these side channel attacks via off-the-shelf equipment and algorithms. We discuss a series of mitigation methods to protect users against these series of attacks.

Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an automated embryo assessment based on a deep learning model. This study includes a total of 1084 images from 1226 embryos. The images were captured by an inverted microscope at day 3 after fertilization. The images were labelled based on Veeck criteria that differentiate embryos to grade 1 to 5 based on the size of the blastomere and the grade of fragmentation. Our deep learning grading results were compared to the grading results from trained embryologists to evaluate the model performance. Our best model from fine-tuning a pre-trained ResNet50 on the dataset results in 91.79% accuracy. The model presented could be developed into an automated embryo assessment method in point-of-care settings.

Financial markets have a vital role in the development of modern society. They allow the deployment of economic resources. Changes in stock prices reflect changes in the market. In this study, we focus on predicting stock prices by deep learning model. This is a challenge task, because there is much noise and uncertainty in information that is related to stock prices. So this work uses sparse autoencoders with one-dimension (1-D) residual convolutional networks which is a deep learning model, to de-noise the data. Long-short term memory (LSTM) is then used to predict the stock price. The prices, indices and macroeconomic variables in past are the features used to predict the next day's price. Experiment results show that 1-D residual convolutional networks can de-noise data and extract deep features better than a model that combines wavelet transforms (WT) and stacked autoencoders (SAEs). In addition, we compare the performances of model with two different forecast targets of stock price: absolute stock price and price rate of change. The results show that predicting stock price through price rate of change is better than predicting absolute prices directly.

The increasing use of two-dimensional (2D) materials in nanoelectronics demands robust metrology techniques for electrical characterization, especially for large-scale production. While atomic force microscopy (AFM) techniques like conductive AFM (C-AFM) offer high accuracy, they suffer from slow data acquisition speeds due to the raster scanning process. To address this, we introduce SparseC-AFM, a deep learning model that rapidly and accurately reconstructs conductivity maps of 2D materials like MoS_2 from sparse C-AFM scans. Our approach is robust across various scanning modes, substrates, and experimental conditions. We report a comparison between (a) classic flow implementation, where a high pixel density C-AFM image (e.g., 15 minutes to collect) is manually parsed to extract relevant material parameters, and (b) our SparseC-AFM method, which achieves the same operation using data that requires substantially less acquisition time (e.g., under 5 minutes). SparseC-AFM enables efficient extraction of critical material parameters in MoS_2, including film coverage, defect density, and identification of crystalline island boundaries, edges, and cracks. We achieve over 11x reduction in acquisition time compared to manual extraction from a full-resolution C-AFM image. Moreover, we demonstrate that our model-predicted samples exhibit remarkably similar electrical properties to full-resolution data gathered using classic-flow scanning. This work represents a significant step toward translating AI-assisted 2D material characterization from laboratory research to industrial fabrication. Code and model weights are available at github.com/UNITES-Lab/sparse-cafm.

We describe a novel approach for developing realistic digital models of dynamic range compressors for digital audio production by analyzing their analog prototypes. While realistic digital dynamic compressors are potentially useful for many applications, the design process is challenging because the compressors operate nonlinearly over long time scales. Our approach is based on the structured state space sequence model (S4), as implementing the state-space model (SSM) has proven to be efficient at learning long-range dependencies and is promising for modeling dynamic range compressors. We present in this paper a deep learning model with S4 layers to model the Teletronix LA-2A analog dynamic range compressor. The model is causal, executes efficiently in real time, and achieves roughly the same quality as previous deep-learning models but with fewer parameters.

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It employs vision transformers, specifically the MaxViT model, for image feature extraction, and self-attention to capture intricate image relationships at the patient level. A dual cross-attention mechanism fuses these features with genetic data, while clinical data is incorporated at the final layer to enhance predictive accuracy. Experiments on the public TCGA-BRCA dataset show that our model, trained using the negative log likelihood loss function, can achieve superior performance with a mean C-index of 0.64, surpassing existing methods. This advancement facilitates tailored treatment strategies, potentially leading to improved patient outcomes.

Cardiac MRI allows for a comprehensive assessment of myocardial structure, function, and tissue characteristics. Here we describe a foundational vision system for cardiac MRI, capable of representing the breadth of human cardiovascular disease and health. Our deep learning model is trained via self-supervised contrastive learning, by which visual concepts in cine-sequence cardiac MRI scans are learned from the raw text of the accompanying radiology reports. We train and evaluate our model on data from four large academic clinical institutions in the United States. We additionally showcase the performance of our models on the UK BioBank, and two additional publicly available external datasets. We explore emergent zero-shot capabilities of our system, and demonstrate remarkable performance across a range of tasks; including the problem of left ventricular ejection fraction regression, and the diagnosis of 35 different conditions such as cardiac amyloidosis and hypertrophic cardiomyopathy. We show that our deep learning system is capable of not only understanding the staggering complexity of human cardiovascular disease, but can be directed towards clinical problems of interest yielding impressive, clinical grade diagnostic accuracy with a fraction of the training data typically required for such tasks.

Deep learning (DL) algorithms have been widely applied to short-term voltage stability (STVS) assessment in power systems. However, transferring the knowledge learned in one power grid to other power grids with topology changes is still a challenging task. This paper proposed a transferable DL-based model for STVS assessment by constructing the topology-aware voltage dynamic features from raw PMU data. Since the reactive power flow and grid topology are essential to voltage stability, the topology-aware and physics-informed voltage dynamic features are utilized to effectively represent the topological and temporal patterns from post-disturbance system dynamic trajectories. The proposed DL-based STVS assessment model is tested under random operating conditions on the New England 39-bus system. It has 99.99\% classification accuracy of the short-term voltage stability status using the topology-aware and physics-informed voltage dynamic features. In addition to high accuracy, the experiments show good adaptability to PMU errors. Moreover, The proposed STVS assessment method has outstanding performance on new grid topologies after fine-tuning. In particular, the highest accuracy reaches 99.68\% in evaluation, which demonstrates a good knowledge transfer ability of the proposed model for power grid topology change.

The TESS mission produces a large amount of time series data, only a small fraction of which contain detectable exoplanetary transit signals. Deep learning techniques such as neural networks have proved effective at differentiating promising astrophysical eclipsing candidates from other phenomena such as stellar variability and systematic instrumental effects in an efficient, unbiased and sustainable manner. This paper presents a high quality dataset containing light curves from the Primary Mission and 1st Extended Mission full frame images and periodic signals detected via Box Least Squares (Kovács et al. 2002; Hartman 2012). The dataset was curated using a thorough manual review process then used to train a neural network called Astronet-Triage-v2. On our test set, for transiting/eclipsing events we achieve a 99.6% recall (true positives over all data with positive labels) at a precision of 75.7% (true positives over all predicted positives). Since 90% of our training data is from the Primary Mission, we also test our ability to generalize on held-out 1st Extended Mission data. Here, we find an area under the precision-recall curve of 0.965, a 4% improvement over Astronet-Triage (Yu et al. 2019). On the TESS Object of Interest (TOI) Catalog through April 2022, a shortlist of planets and planet candidates, Astronet-Triage-v2 is able to recover 3577 out of 4140 TOIs, while Astronet-Triage only recovers 3349 targets at an equal level of precision. In other words, upgrading to Astronet-Triage-v2 helps save at least 200 planet candidates from being lost. The new model is currently used for planet candidate triage in the Quick-Look Pipeline (Huang et al. 2020a,b; Kunimoto et al. 2021).

The disorder of urban streetscapes would negatively affect people's perception of their aesthetic quality. The presence of billboards on building facades has been regarded as an important factor of the disorder, but its quantification methodology has not yet been developed in a scalable manner. To fill the gap, this paper reports the performance of our deep learning model on a unique data set prepared in Tokyo to recognize the areas covered by facades and billboards in streetscapes, respectively. The model achieved 63.17 % of accuracy, measured by Intersection-over-Union (IoU), thus enabling researchers and practitioners to obtain insights on urban streetscape design by combining data of people's preferences.

We present the full-size Russian complexly NER-labeled corpus of Internet user reviews, along with an evaluation of accuracy levels reached on this corpus by a set of advanced deep learning neural networks to extract the pharmacologically meaningful entities from Russian texts. The corpus annotation includes mentions of the following entities: Medication (33005 mentions), Adverse Drug Reaction (1778), Disease (17403), and Note (4490). Two of them - Medication and Disease - comprise a set of attributes. A part of the corpus has the coreference annotation with 1560 coreference chains in 300 documents. Special multi-label model based on a language model and the set of features is developed, appropriate for presented corpus labeling. The influence of the choice of different modifications of the models: word vector representations, types of language models pre-trained for Russian, text normalization styles, and other preliminary processing are analyzed. The sufficient size of our corpus allows to study the effects of particularities of corpus labeling and balancing entities in the corpus. As a result, the state of the art for the pharmacological entity extraction problem for Russian is established on a full-size labeled corpus. In case of the adverse drug reaction (ADR) recognition, it is 61.1 by the F1-exact metric that, as our analysis shows, is on par with the accuracy level for other language corpora with similar characteristics and the ADR representativnes. The evaluated baseline precision of coreference relation extraction on the corpus is 71, that is higher the results reached on other Russian corpora.

Khmer text is written from left to right with optional space. Space is not served as a word boundary but instead, it is used for readability or other functional purposes. Word segmentation is a prior step for downstream tasks such as part-of-speech (POS) tagging and thus, the robustness of POS tagging highly depends on word segmentation. The conventional Khmer POS tagging is a two-stage process that begins with word segmentation and then actual tagging of each word, afterward. In this work, a joint word segmentation and POS tagging approach using a single deep learning model is proposed so that word segmentation and POS tagging can be performed spontaneously. The proposed model was trained and tested using the publicly available Khmer POS dataset. The validation suggested that the performance of the joint model is on par with the conventional two-stage POS tagging.

Purpose: The need to streamline patient management for COVID-19 has become more pressing than ever. Chest X-rays provide a non-invasive (potentially bedside) tool to monitor the progression of the disease. In this study, we present a severity score prediction model for COVID-19 pneumonia for frontal chest X-ray images. Such a tool can gauge severity of COVID-19 lung infections (and pneumonia in general) that can be used for escalation or de-escalation of care as well as monitoring treatment efficacy, especially in the ICU. Methods: Images from a public COVID-19 database were scored retrospectively by three blinded experts in terms of the extent of lung involvement as well as the degree of opacity. A neural network model that was pre-trained on large (non-COVID-19) chest X-ray datasets is used to construct features for COVID-19 images which are predictive for our task. Results: This study finds that training a regression model on a subset of the outputs from an this pre-trained chest X-ray model predicts our geographic extent score (range 0-8) with 1.14 mean absolute error (MAE) and our lung opacity score (range 0-6) with 0.78 MAE. Conclusions: These results indicate that our model's ability to gauge severity of COVID-19 lung infections could be used for escalation or de-escalation of care as well as monitoring treatment efficacy, especially in the intensive care unit (ICU). A proper clinical trial is needed to evaluate efficacy. To enable this we make our code, labels, and data available online at https://github.com/mlmed/torchxrayvision/tree/master/scripts/covid-severity and https://github.com/ieee8023/covid-chestxray-dataset

Advancements in genomic research such as high-throughput sequencing techniques have driven modern genomic studies into "big data" disciplines. This data explosion is constantly challenging conventional methods used in genomics. In parallel with the urgent demand for robust algorithms, deep learning has succeeded in a variety of fields such as vision, speech, and text processing. Yet genomics entails unique challenges to deep learning since we are expecting from deep learning a superhuman intelligence that explores beyond our knowledge to interpret the genome. A powerful deep learning model should rely on insightful utilization of task-specific knowledge. In this paper, we briefly discuss the strengths of different deep learning models from a genomic perspective so as to fit each particular task with a proper deep architecture, and remark on practical considerations of developing modern deep learning architectures for genomics. We also provide a concise review of deep learning applications in various aspects of genomic research, as well as pointing out potential opportunities and obstacles for future genomics applications.

The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate the extraction of interpretable features for biomarker discovery. However, these models are typically trained for a single task and therefore scale poorly as we wish to adapt the model for an increasing number of different tasks. Also, supervised deep learning models are very data hungry and therefore rely on large amounts of training data to perform well. In this paper, we present a multi-task learning approach for segmentation and classification of nuclei, glands, lumina and different tissue regions that leverages data from multiple independent data sources. While ensuring that our tasks are aligned by the same tissue type and resolution, we enable meaningful simultaneous prediction with a single network. As a result of feature sharing, we also show that the learned representation can be used to improve the performance of additional tasks via transfer learning, including nuclear classification and signet ring cell detection. As part of this work, we train our developed Cerberus model on a huge amount of data, consisting of over 600K objects for segmentation and 440K patches for classification. We use our approach to process 599 colorectal whole-slide images from TCGA, where we localise 377 million, 900K and 2.1 million nuclei, glands and lumina, respectively and make the results available to the community for downstream analysis.

We present a parsimonious deep learning weather prediction model to forecast seven atmospheric variables with 3-h time resolution for up to one-year lead times on a 110-km global mesh using the Hierarchical Equal Area isoLatitude Pixelization (HEALPix). In comparison to state-of-the-art (SOTA) machine learning (ML) weather forecast models, such as Pangu-Weather and GraphCast, our DLWP-HPX model uses coarser resolution and far fewer prognostic variables. Yet, at one-week lead times, its skill is only about one day behind both SOTA ML forecast models and the SOTA numerical weather prediction model from the European Centre for Medium-Range Weather Forecasts. We report several improvements in model design, including switching from the cubed sphere to the HEALPix mesh, inverting the channel depth of the U-Net, and introducing gated recurrent units (GRU) on each level of the U-Net hierarchy. The consistent east-west orientation of all cells on the HEALPix mesh facilitates the development of location-invariant convolution kernels that successfully propagate weather patterns across the globe without requiring separate kernels for the polar and equatorial faces of the cube sphere. Without any loss of spectral power after the first two days, the model can be unrolled autoregressively for hundreds of steps into the future to generate realistic states of the atmosphere that respect seasonal trends, as showcased in one-year simulations.

Advances in underwater imaging enable the collection of extensive seafloor image datasets that are necessary for monitoring important benthic ecosystems. The ability to collect seafloor imagery has outpaced our capacity to analyze it, hindering expedient mobilization of this crucial environmental information. Recent machine learning approaches provide opportunities to increase the efficiency with which seafloor image datasets are analyzed, yet large and consistent datasets necessary to support development of such approaches are scarce. Here we present BenthicNet: a global compilation of seafloor imagery designed to support the training and evaluation of large-scale image recognition models. An initial set of over 11.4 million images was collected and curated to represent a diversity of seafloor environments using a representative subset of 1.3 million images. These are accompanied by 2.6 million annotations translated to the CATAMI scheme, which span 190,000 of the images. A large deep learning model was trained on this compilation and preliminary results suggest it has utility for automating large and small-scale image analysis tasks. The compilation and model are made openly available for use by the scientific community at https://doi.org/10.20383/103.0614.

In this work, product tables in invoices are obtained autonomously via a deep learning model, which is named as ExTTNet. Firstly, text is obtained from invoice images using Optical Character Recognition (OCR) techniques. Tesseract OCR engine [37] is used for this process. Afterwards, the number of existing features is increased by using feature extraction methods to increase the accuracy. Labeling process is done according to whether each text obtained as a result of OCR is a table element or not. In this study, a multilayer artificial neural network model is used. The training has been carried out with an Nvidia RTX 3090 graphics card and taken 162 minutes. As a result of the training, the F1 score is 0.92.

My research investigates the use of cutting-edge hybrid deep learning models to accurately differentiate between AI-generated text and human writing. I applied a robust methodology, utilising a carefully selected dataset comprising AI and human texts from various sources, each tagged with instructions. Advanced natural language processing techniques facilitated the analysis of textual features. Combining sophisticated neural networks, the custom model enabled it to detect nuanced differences between AI and human content.

Study Objectives: We investigate a Mamba-based deep learning approach for sleep staging on signals from ANNE One (Sibel Health, Evanston, IL), a non-intrusive dual-module wireless wearable system measuring chest electrocardiography (ECG), triaxial accelerometry, and chest temperature, and finger photoplethysmography and finger temperature. Methods: We obtained wearable sensor recordings from 357 adults undergoing concurrent polysomnography (PSG) at a tertiary care sleep lab. Each PSG recording was manually scored and these annotations served as ground truth labels for training and evaluation of our models. PSG and wearable sensor data were automatically aligned using their ECG channels with manual confirmation by visual inspection. We trained a Mamba-based recurrent neural network architecture on these recordings. Ensembling of model variants with similar architectures was performed. Results: After ensembling, the model attains a 3-class (wake, non rapid eye movement [NREM] sleep, rapid eye movement [REM] sleep) balanced accuracy of 84.02%, F1 score of 84.23%, Cohen's κ of 72.89%, and a Matthews correlation coefficient (MCC) score of 73.00%; a 4-class (wake, light NREM [N1/N2], deep NREM [N3], REM) balanced accuracy of 75.30%, F1 score of 74.10%, Cohen's κ of 61.51%, and MCC score of 61.95%; a 5-class (wake, N1, N2, N3, REM) balanced accuracy of 65.11%, F1 score of 66.15%, Cohen's κ of 53.23%, MCC score of 54.38%. Conclusions: Our Mamba-based deep learning model can successfully infer major sleep stages from the ANNE One, a wearable system without electroencephalography (EEG), and can be applied to data from adults attending a tertiary care sleep clinic.

Writing tests is a time-consuming yet essential task during software development. We propose to leverage recent advances in deep learning for text and code generation to assist developers in writing tests. We formalize the novel task of test completion to automatically complete the next statement in a test method based on the context of prior statements and the code under test. We develop TeCo -- a deep learning model using code semantics for test completion. The key insight underlying TeCo is that predicting the next statement in a test method requires reasoning about code execution, which is hard to do with only syntax-level data that existing code completion models use. TeCo extracts and uses six kinds of code semantics data, including the execution result of prior statements and the execution context of the test method. To provide a testbed for this new task, as well as to evaluate TeCo, we collect a corpus of 130,934 test methods from 1,270 open-source Java projects. Our results show that TeCo achieves an exact-match accuracy of 18, which is 29% higher than the best baseline using syntax-level data only. When measuring functional correctness of generated next statement, TeCo can generate runnable code in 29% of the cases compared to 18% obtained by the best baseline. Moreover, TeCo is significantly better than prior work on test oracle generation.

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet, a supervised deep-learning model to predict the fitness for protein mutants by leveraging both sequence and structure information, and exploiting attention mechanism. Our model integrates local evolutionary context from homologous sequences, the global evolutionary context encoding rich semantic from the universal protein sequence space and the structure information accounting for the microenvironment around each residue in a protein. We show that SESNet outperforms state-of-the-art models for predicting the sequence-function relationship on 26 deep mutational scanning datasets. More importantly, we propose a data augmentation strategy by leveraging the data from unsupervised models to pre-train our model. After that, our model can achieve strikingly high accuracy in prediction of the fitness of protein mutants, especially for the higher order variants (> 4 mutation sites), when finetuned by using only a small number of experimental mutation data (<50). The strategy proposed is of great practical value as the required experimental effort, i.e., producing a few tens of experimental mutation data on a given protein, is generally affordable by an ordinary biochemical group and can be applied on almost any protein.

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development of data-driven and, in particular, deep learning methods for various tasks such as cancer diagnosis, detection, prognosis, and prediction. Despite recent successes, however, designing high-performing deep learning models for nonimage and nontext cancer data is a time-consuming, trial-and-error, manual task that requires both cancer domain and deep learning expertise. To that end, we develop a reinforcement-learning-based neural architecture search to automate deep-learning-based predictive model development for a class of representative cancer data. We develop custom building blocks that allow domain experts to incorporate the cancer-data-specific characteristics. We show that our approach discovers deep neural network architectures that have significantly fewer trainable parameters, shorter training time, and accuracy similar to or higher than those of manually designed architectures. We study and demonstrate the scalability of our approach on up to 1,024 Intel Knights Landing nodes of the Theta supercomputer at the Argonne Leadership Computing Facility.

Using a large-scale Deep Learning approach applied to a high-frequency database containing billions of electronic market quotes and transactions for US equities, we uncover nonparametric evidence for the existence of a universal and stationary price formation mechanism relating the dynamics of supply and demand for a stock, as revealed through the order book, to subsequent variations in its market price. We assess the model by testing its out-of-sample predictions for the direction of price moves given the history of price and order flow, across a wide range of stocks and time periods. The universal price formation model is shown to exhibit a remarkably stable out-of-sample prediction accuracy across time, for a wide range of stocks from different sectors. Interestingly, these results also hold for stocks which are not part of the training sample, showing that the relations captured by the model are universal and not asset-specific. The universal model --- trained on data from all stocks --- outperforms, in terms of out-of-sample prediction accuracy, asset-specific linear and nonlinear models trained on time series of any given stock, showing that the universal nature of price formation weighs in favour of pooling together financial data from various stocks, rather than designing asset- or sector-specific models as commonly done. Standard data normalizations based on volatility, price level or average spread, or partitioning the training data into sectors or categories such as large/small tick stocks, do not improve training results. On the other hand, inclusion of price and order flow history over many past observations is shown to improve forecasting performance, showing evidence of path-dependence in price dynamics.

The automated generation of test code can reduce the time and effort required to build software while increasing its correctness and robustness. In this paper, we present RE-ASSERT, an approach for the automated generation of JUnit test asserts which produces more accurate asserts than previous work with fewer constraints. This is achieved by targeting projects individually, using precise code-to-test traceability for learning and by generating assert statements from the method-under-test directly without the need to write an assert-less test first. We also utilise Reformer, a state-of-the-art deep learning model, along with two models from previous work to evaluate ReAssert and an existing approach, known as ATLAS, using lexical accuracy,uniqueness, and dynamic analysis. Our evaluation of ReAssert shows up to 44% of generated asserts for a single project match exactly with the ground truth, increasing to 51% for generated asserts that compile. We also improve on the ATLAS results through our use of Reformer with 28% of generated asserts matching exactly with the ground truth. Reformer also produces the greatest proportion of unique asserts (71%), giving further evidence that Reformer produces the most useful asserts.

Analyzing the ever-increasing volume of posts on social media sites such as Facebook and Twitter requires improved information processing methods for profiling authorship. Document classification is central to this task, but the performance of traditional supervised classifiers has degraded as the volume of social media has increased. This paper addresses this problem in the context of gender detection through ensemble classification that employs multi-model deep learning architectures to generate specialized understanding from different feature spaces.

Over the past decade, the study of extrasolar planets has evolved rapidly from plain detection and identification to comprehensive categorization and characterization of exoplanet systems and their atmospheres. Atmospheric retrieval, the inverse modeling technique used to determine an exoplanetary atmosphere's temperature structure and composition from an observed spectrum, is both time-consuming and compute-intensive, requiring complex algorithms that compare thousands to millions of atmospheric models to the observational data to find the most probable values and associated uncertainties for each model parameter. For rocky, terrestrial planets, the retrieved atmospheric composition can give insight into the surface fluxes of gaseous species necessary to maintain the stability of that atmosphere, which may in turn provide insight into the geological and/or biological processes active on the planet. These atmospheres contain many molecules, some of them biosignatures, spectral fingerprints indicative of biological activity, which will become observable with the next generation of telescopes. Runtimes of traditional retrieval models scale with the number of model parameters, so as more molecular species are considered, runtimes can become prohibitively long. Recent advances in machine learning (ML) and computer vision offer new ways to reduce the time to perform a retrieval by orders of magnitude, given a sufficient data set to train with. Here we present an ML-based retrieval framework called Intelligent exoplaNet Atmospheric RetrievAl (INARA) that consists of a Bayesian deep learning model for retrieval and a data set of 3,000,000 synthetic rocky exoplanetary spectra generated using the NASA Planetary Spectrum Generator. Our work represents the first ML retrieval model for rocky, terrestrial exoplanets and the first synthetic data set of terrestrial spectra generated at this scale.

Strapdown inertial navigation systems are sensitive to the quality of the data provided by the accelerometer and gyroscope. Low-grade IMUs in handheld smart-devices pose a problem for inertial odometry on these devices. We propose a scheme for constraining the inertial odometry problem by complementing non-linear state estimation by a CNN-based deep-learning model for inferring the momentary speed based on a window of IMU samples. We show the feasibility of the model using a wide range of data from an iPhone, and present proof-of-concept results for how the model can be combined with an inertial navigation system for three-dimensional inertial navigation.

We present the first deep learning model to successfully learn control policies directly from high-dimensional sensory input using reinforcement learning. The model is a convolutional neural network, trained with a variant of Q-learning, whose input is raw pixels and whose output is a value function estimating future rewards. We apply our method to seven Atari 2600 games from the Arcade Learning Environment, with no adjustment of the architecture or learning algorithm. We find that it outperforms all previous approaches on six of the games and surpasses a human expert on three of them.

The increasing complexity of Artificial Intelligence models poses challenges to interpretability, particularly in the healthcare sector. This study investigates the impact of deep learning model complexity and Explainable AI (XAI) efficacy, utilizing four ResNet architectures (ResNet-18, 34, 50, 101). Through methodical experimentation on 4,369 lung X-ray images of COVID-19-infected and healthy patients, the research evaluates models' classification performance and the relevance of corresponding XAI explanations with respect to the ground-truth disease masks. Results indicate that the increase in model complexity is associated with a decrease in classification accuracy and AUC-ROC scores (ResNet-18: 98.4%, 0.997; ResNet-101: 95.9%, 0.988). Notably, in eleven out of twelve statistical tests performed, no statistically significant differences occurred between XAI quantitative metrics - Relevance Rank Accuracy and the proposed Positive Attribution Ratio - across trained models. These results suggest that increased model complexity does not consistently lead to higher performance or relevance of explanations for models' decision-making processes.

The Quran is the holy scripture of Islam, and its recitation is an important aspect of the religion. Recognizing the recitation of the Holy Quran automatically is a challenging task due to its unique rules that are not applied in normal speaking speeches. A lot of research has been done in this domain, but previous works have detected recitation errors as a classification task or used traditional automatic speech recognition (ASR). In this paper, we proposed a novel end-to-end deep learning model for recognizing the recitation of the Holy Quran. The proposed model is a CNN-Bidirectional GRU encoder that uses CTC as an objective function, and a character-based decoder which is a beam search decoder. Moreover, all previous works were done on small private datasets consisting of short verses and a few chapters of the Holy Quran. As a result of using private datasets, no comparisons were done. To overcome this issue, we used a public dataset that has recently been published (Ar-DAD) and contains about 37 chapters that were recited by 30 reciters, with different recitation speeds and different types of pronunciation rules. The proposed model performance was evaluated using the most common evaluation metrics in speech recognition, word error rate (WER), and character error rate (CER). The results were 8.34% WER and 2.42% CER. We hope this research will be a baseline for comparisons with future research on this public new dataset (Ar-DAD).

Introduction: Sleep staging is an essential component in the diagnosis of sleep disorders and management of sleep health. It is traditionally measured in a clinical setting and requires a labor-intensive labeling process. We hypothesize that it is possible to perform robust 4-class sleep staging using the raw photoplethysmography (PPG) time series and modern advances in deep learning (DL). Methods: We used two publicly available sleep databases that included raw PPG recordings, totalling 2,374 patients and 23,055 hours. We developed SleepPPG-Net, a DL model for 4-class sleep staging from the raw PPG time series. SleepPPG-Net was trained end-to-end and consists of a residual convolutional network for automatic feature extraction and a temporal convolutional network to capture long-range contextual information. We benchmarked the performance of SleepPPG-Net against models based on the best-reported state-of-the-art (SOTA) algorithms. Results: When benchmarked on a held-out test set, SleepPPG-Net obtained a median Cohen's Kappa (κ) score of 0.75 against 0.69 for the best SOTA approach. SleepPPG-Net showed good generalization performance to an external database, obtaining a κ score of 0.74 after transfer learning. Perspective: Overall, SleepPPG-Net provides new SOTA performance. In addition, performance is high enough to open the path to the development of wearables that meet the requirements for usage in clinical applications such as the diagnosis and monitoring of obstructive sleep apnea.

Predicting how a drug-like molecule binds to a specific protein target is a core problem in drug discovery. An extremely fast computational binding method would enable key applications such as fast virtual screening or drug engineering. Existing methods are computationally expensive as they rely on heavy candidate sampling coupled with scoring, ranking, and fine-tuning steps. We challenge this paradigm with EquiBind, an SE(3)-equivariant geometric deep learning model performing direct-shot prediction of both i) the receptor binding location (blind docking) and ii) the ligand's bound pose and orientation. EquiBind achieves significant speed-ups and better quality compared to traditional and recent baselines. Further, we show extra improvements when coupling it with existing fine-tuning techniques at the cost of increased running time. Finally, we propose a novel and fast fine-tuning model that adjusts torsion angles of a ligand's rotatable bonds based on closed-form global minima of the von Mises angular distance to a given input atomic point cloud, avoiding previous expensive differential evolution strategies for energy minimization.

The success of Transformer models has pushed the deep learning model scale to billions of parameters. Due to the limited memory resource of a single GPU, However, the best practice for choosing the optimal parallel strategy is still lacking, since it requires domain expertise in both deep learning and parallel computing. The Colossal-AI system addressed the above challenge by introducing a unified interface to scale your sequential code of model training to distributed environments. It supports parallel training methods such as data, pipeline, tensor, and sequence parallelism, as well as heterogeneous training methods integrated with zero redundancy optimizer. Compared to the baseline system, Colossal-AI can achieve up to 2.76 times training speedup on large-scale models.

In this work we present Ludwig, a flexible, extensible and easy to use toolbox which allows users to train deep learning models and use them for obtaining predictions without writing code. Ludwig implements a novel approach to deep learning model building based on two main abstractions: data types and declarative configuration files. The data type abstraction allows for easier code and sub-model reuse, and the standardized interfaces imposed by this abstraction allow for encapsulation and make the code easy to extend. Declarative model definition configuration files enable inexperienced users to obtain effective models and increase the productivity of expert users. Alongside these two innovations, Ludwig introduces a general modularized deep learning architecture called Encoder-Combiner-Decoder that can be instantiated to perform a vast amount of machine learning tasks. These innovations make it possible for engineers, scientists from other fields and, in general, a much broader audience to adopt deep learning models for their tasks, concretely helping in its democratization.

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to reflect a model's true decision process. Prototype-based reasoning offers a more transparent alternative by grounding decisions in similarity to learned representations of real ECG segments, enabling faithful, case-based explanations. We introduce ProtoECGNet, a prototype-based deep learning model for interpretable, multi-label ECG classification. ProtoECGNet employs a structured, multi-branch architecture that reflects clinical interpretation workflows: it integrates a 1D CNN with global prototypes for rhythm classification, a 2D CNN with time-localized prototypes for morphology-based reasoning, and a 2D CNN with global prototypes for diffuse abnormalities. Each branch is trained with a prototype loss designed for multi-label learning, combining clustering, separation, diversity, and a novel contrastive loss that encourages appropriate separation between prototypes of unrelated classes while allowing clustering for frequently co-occurring diagnoses. We evaluate ProtoECGNet on all 71 diagnostic labels from the PTB-XL dataset, demonstrating competitive performance relative to state-of-the-art black-box models while providing structured, case-based explanations. To assess prototype quality, we conduct a structured clinician review of the final model's projected prototypes, finding that they are rated as representative and clear. ProtoECGNet shows that prototype learning can be effectively scaled to complex, multi-label time-series classification, offering a practical path toward transparent and trustworthy deep learning models for clinical decision support.

Accurate extraction of heart rate from photoplethysmography (PPG) signals remains challenging due to motion artifacts and signal degradation. Although deep learning methods trained as a data-driven inference problem offer promising solutions, they often underutilize existing knowledge from the medical and signal processing community. In this paper, we address three shortcomings of deep learning models: motion artifact removal, degradation assessment, and physiologically plausible analysis of the PPG signal. We propose KID-PPG, a knowledge-informed deep learning model that integrates expert knowledge through adaptive linear filtering, deep probabilistic inference, and data augmentation. We evaluate KID-PPG on the PPGDalia dataset, achieving an average mean absolute error of 2.85 beats per minute, surpassing existing reproducible methods. Our results demonstrate a significant performance improvement in heart rate tracking through the incorporation of prior knowledge into deep learning models. This approach shows promise in enhancing various biomedical applications by incorporating existing expert knowledge in deep learning models.

Full-complexity Earth system models (ESMs) are computationally very expensive, limiting their use in exploring the climate outcomes of multiple emission pathways. More efficient emulators that approximate ESMs can directly map emissions onto climate outcomes, and benchmarks are being used to evaluate their accuracy on standardized tasks and datasets. We investigate a popular benchmark in data-driven climate emulation, ClimateBench, on which deep learning-based emulators are currently achieving the best performance. We implement a linear regression-based emulator, akin to pattern scaling, and find that it outperforms the incumbent 100M-parameter deep learning foundation model, ClimaX, on 3 out of 4 regionally-resolved surface-level climate variables. While emulating surface temperature is expected to be predominantly linear, this result is surprising for emulating precipitation. We identify that this outcome is a result of high levels of internal variability in the benchmark targets. To address internal variability, we update the benchmark targets with ensemble averages from the MPI-ESM1.2-LR model that contain 50 instead of 3 climate simulations per emission pathway. Using the new targets, we show that linear pattern scaling continues to be more accurate on temperature, but can be outperformed by a deep learning-based model for emulating precipitation. We publish our code, data, and an interactive tutorial at github.com/blutjens/climate-emulator.

Although deep learning models have demonstrated remarkable potential in weather prediction, most of them overlook either the physics of the underlying weather evolution or the topology of the Earth's surface. In light of these disadvantages, we develop PASSAT, a novel Physics-ASSisted And Topology-informed deep learning model for weather prediction. PASSAT attributes the weather evolution to two key factors: (i) the advection process that can be characterized by the advection equation and the Navier-Stokes equation; (ii) the Earth-atmosphere interaction that is difficult to both model and calculate. PASSAT also takes the topology of the Earth's surface into consideration, other than simply treating it as a plane. With these considerations, PASSAT numerically solves the advection equation and the Navier-Stokes equation on the spherical manifold, utilizes a spherical graph neural network to capture the Earth-atmosphere interaction, and generates the initial velocity fields that are critical to solving the advection equation from the same spherical graph neural network. In the 5.625^circ-resolution ERA5 data set, PASSAT outperforms both the state-of-the-art deep learning-based weather prediction models and the operational numerical weather prediction model IFS T42. Code and checkpoint are available at https://github.com/Yumenomae/PASSAT_5p625.

Characterizing the processes leading to deforestation is critical to the development and implementation of targeted forest conservation and management policies. In this work, we develop a deep learning model called ForestNet to classify the drivers of primary forest loss in Indonesia, a country with one of the highest deforestation rates in the world. Using satellite imagery, ForestNet identifies the direct drivers of deforestation in forest loss patches of any size. We curate a dataset of Landsat 8 satellite images of known forest loss events paired with driver annotations from expert interpreters. We use the dataset to train and validate the models and demonstrate that ForestNet substantially outperforms other standard driver classification approaches. In order to support future research on automated approaches to deforestation driver classification, the dataset curated in this study is publicly available at https://stanfordmlgroup.github.io/projects/forestnet .

Deep learning methods for image quality assessment (IQA) are limited due to the small size of existing datasets. Extensive datasets require substantial resources both for generating publishable content and annotating it accurately. We present a systematic and scalable approach to creating KonIQ-10k, the largest IQA dataset to date, consisting of 10,073 quality scored images. It is the first in-the-wild database aiming for ecological validity, concerning the authenticity of distortions, the diversity of content, and quality-related indicators. Through the use of crowdsourcing, we obtained 1.2 million reliable quality ratings from 1,459 crowd workers, paving the way for more general IQA models. We propose a novel, deep learning model (KonCept512), to show an excellent generalization beyond the test set (0.921 SROCC), to the current state-of-the-art database LIVE-in-the-Wild (0.825 SROCC). The model derives its core performance from the InceptionResNet architecture, being trained at a higher resolution than previous models (512x384). Correlation analysis shows that KonCept512 performs similar to having 9 subjective scores for each test image.

On-device deep learning (DL) has rapidly gained adoption in mobile apps, offering the benefits of offline model inference and user privacy preservation over cloud-based approaches. However, it inevitably stores models on user devices, introducing new vulnerabilities, particularly model-stealing attacks and intellectual property infringement. While system-level protections like Trusted Execution Environments (TEEs) provide a robust solution, practical challenges remain in achieving scalable on-device DL model protection, including complexities in supporting third-party models and limited adoption in current mobile solutions. Advancements in TEE-enabled hardware, such as NVIDIA's GPU-based TEEs, may address these obstacles in the future. Currently, watermarking serves as a common defense against model theft but also faces challenges here as many mobile app developers lack corresponding machine learning expertise and the inherent read-only and inference-only nature of on-device DL models prevents third parties like app stores from implementing existing watermarking techniques in post-deployment models. To protect the intellectual property of on-device DL models, in this paper, we propose THEMIS, an automatic tool that lifts the read-only restriction of on-device DL models by reconstructing their writable counterparts and leverages the untrainable nature of on-device DL models to solve watermark parameters and protect the model owner's intellectual property. Extensive experimental results across various datasets and model structures show the superiority of THEMIS in terms of different metrics. Further, an empirical investigation of 403 real-world DL mobile apps from Google Play is performed with a success rate of 81.14%, showing the practicality of THEMIS.

Deep learning (DL) models for tabular data problems are receiving increasingly more attention, while the algorithms based on gradient-boosted decision trees (GBDT) remain a strong go-to solution. Following the recent trends in other domains, such as natural language processing and computer vision, several retrieval-augmented tabular DL models have been recently proposed. For a given target object, a retrieval-based model retrieves other relevant objects, such as the nearest neighbors, from the available (training) data and uses their features or even labels to make a better prediction. However, we show that the existing retrieval-based tabular DL solutions provide only minor, if any, benefits over the properly tuned simple retrieval-free baselines. Thus, it remains unclear whether the retrieval-based approach is a worthy direction for tabular DL. In this work, we give a strong positive answer to this question. We start by incrementally augmenting a simple feed-forward architecture with an attention-like retrieval component similar to those of many (tabular) retrieval-based models. Then, we highlight several details of the attention mechanism that turn out to have a massive impact on the performance on tabular data problems, but that were not explored in prior work. As a result, we design TabR -- a simple retrieval-based tabular DL model which, on a set of public benchmarks, demonstrates the best average performance among tabular DL models, becomes the new state-of-the-art on several datasets, and even outperforms GBDT models on the recently proposed ``GBDT-friendly'' benchmark (see the first figure).

Within the scope of natural language processing, the domain of multi-label text classification is uniquely challenging due to its expansive and uneven label distribution. The complexity deepens due to the demand for an extensive set of annotated data for training an advanced deep learning model, especially in specialized fields where the labeling task can be labor-intensive and often requires domain-specific knowledge. Addressing these challenges, our study introduces a novel deep active learning strategy, capitalizing on the Beta family of proper scoring rules within the Expected Loss Reduction framework. It computes the expected increase in scores using the Beta Scoring Rules, which are then transformed into sample vector representations. These vector representations guide the diverse selection of informative samples, directly linking this process to the model's expected proper score. Comprehensive evaluations across both synthetic and real datasets reveal our method's capability to often outperform established acquisition techniques in multi-label text classification, presenting encouraging outcomes across various architectural and dataset scenarios.

Polymicrogyria (PMG) is a disorder of cortical organization mainly seen in children, which can be associated with seizures, developmental delay and motor weakness. PMG is typically diagnosed on magnetic resonance imaging (MRI) but some cases can be challenging to detect even for experienced radiologists. In this study, we create an open pediatric MRI dataset (PPMR) with PMG and controls from the Children's Hospital of Eastern Ontario (CHEO), Ottawa, Canada. The differences between PMG MRIs and control MRIs are subtle and the true distribution of the features of the disease is unknown. This makes automatic detection of cases of potential PMG in MRI difficult. We propose an anomaly detection method based on a novel center-based deep contrastive metric learning loss function (cDCM) which enables the automatic detection of cases of potential PMG. Additionally, based on our proposed loss function, we customize a deep learning model structure that integrates dilated convolution, squeeze-and-excitation blocks and feature fusion for our PPMR dataset. Despite working with a small and imbalanced dataset our method achieves 92.01% recall at 55.04% precision. This will facilitate a computer aided tool for radiologists to select potential PMG MRIs. To the best of our knowledge, this research is the first to apply machine learning techniques to identify PMG from MRI only.

We introduce Gravity, another algorithm for gradient-based optimization. In this paper, we explain how our novel idea change parameters to reduce the deep learning model's loss. It has three intuitive hyper-parameters that the best values for them are proposed. Also, we propose an alternative to moving average. To compare the performance of the Gravity optimizer with two common optimizers, Adam and RMSProp, five standard datasets were trained on two VGGNet models with a batch size of 128 for 100 epochs. Gravity hyper-parameters did not need to be tuned for different models. As will be explained more in the paper, to investigate the direct impact of the optimizer itself on loss reduction no overfitting prevention technique was used. The obtained results show that the Gravity optimizer has more stable performance than Adam and RMSProp and gives greater values of validation accuracy for datasets with more output classes like CIFAR-100 (Fine).

This study presents the first investigation of pedestrian crash severity using the TabNet model, a novel tabular deep learning method exceptionally suited for analyzing the tabular data inherent in transportation safety research. Through the application of TabNet to a comprehensive dataset from Utah covering the years 2010 to 2022, we uncover intricate factors contributing to pedestrian crash severity. The TabNet model, capitalizing on its compatibility with structured data, demonstrates remarkable predictive accuracy, eclipsing that of traditional models. It identifies critical variables, such as pedestrian age, involvement in left or right turns, lighting conditions, and alcohol consumption, which significantly influence crash outcomes. The utilization of SHapley Additive exPlanations (SHAP) enhances our ability to interpret the TabNet model's predictions, ensuring transparency and understandability in our deep learning approach. The insights derived from our analysis provide a valuable compass for transportation safety engineers and policymakers, enabling the identification of pivotal factors that affect pedestrian crash severity. Such knowledge is instrumental in formulating precise, data-driven interventions aimed at bolstering pedestrian safety across diverse urban and rural settings.

For a long-time, researchers have been developing a reliable and accurate predictive model for stock price prediction. According to the literature, if predictive models are correctly designed and refined, they can painstakingly and faithfully estimate future stock values. This paper demonstrates a set of time series, econometric, and various learning-based models for stock price prediction. The data of Infosys, ICICI, and SUN PHARMA from the period of January 2004 to December 2019 was used here for training and testing the models to know which model performs best in which sector. One time series model (Holt-Winters Exponential Smoothing), one econometric model (ARIMA), two machine Learning models (Random Forest and MARS), and two deep learning-based models (simple RNN and LSTM) have been included in this paper. MARS has been proved to be the best performing machine learning model, while LSTM has proved to be the best performing deep learning model. But overall, for all three sectors - IT (on Infosys data), Banking (on ICICI data), and Health (on SUN PHARMA data), MARS has proved to be the best performing model in sales forecasting.

Precipitation nowcasting is critical for disaster mitigation and aviation safety. However, radar-only models frequently suffer from a lack of large-scale atmospheric context, leading to performance degradation at longer lead times. While integrating meteorological variables predicted by weather foundation models offers a potential remedy, existing architectures fail to reconcile the profound representational heterogeneities between radar imagery and meteorological data. To bridge this gap, we propose PW-FouCast, a novel frequency-domain fusion framework that leverages Pangu-Weather forecasts as spectral priors within a Fourier-based backbone. Our architecture introduces three key innovations: (i) Pangu-Weather-guided Frequency Modulation to align spectral magnitudes and phases with meteorological priors; (ii) Frequency Memory to correct phase discrepancies and preserve temporal evolution; and (iii) Inverted Frequency Attention to reconstruct high-frequency details typically lost in spectral filtering. Extensive experiments on the SEVIR and MeteoNet benchmarks demonstrate that PW-FouCast achieves state-of-the-art performance, effectively extending the reliable forecast horizon while maintaining structural fidelity. Our code is available at https://github.com/Onemissed/PW-FouCast.

White balance (WB) algorithms in many commercial cameras assume single and uniform illumination, leading to undesirable results when multiple lighting sources with different chromaticities exist in the scene. Prior research on multi-illuminant WB typically predicts illumination at the pixel level without fully grasping the scene's actual lighting conditions, including the number and color of light sources. This often results in unnatural outcomes lacking in overall consistency. To handle this problem, we present a deep white balancing model that leverages the slot attention, where each slot is in charge of representing individual illuminants. This design enables the model to generate chromaticities and weight maps for individual illuminants, which are then fused to compose the final illumination map. Furthermore, we propose the centroid-matching loss, which regulates the activation of each slot based on the color range, thereby enhancing the model to separate illumination more effectively. Our method achieves the state-of-the-art performance on both single- and multi-illuminant WB benchmarks, and also offers additional information such as the number of illuminants in the scene and their chromaticity. This capability allows for illumination editing, an application not feasible with prior methods.

In the realm of robot action recognition, identifying distinct but spatially proximate arm movements using vision systems in noisy environments poses a significant challenge. This paper studies robot arm action recognition in noisy environments using machine learning techniques. Specifically, a vision system is used to track the robot's movements followed by a deep learning model to extract the arm's key points. Through a comparative analysis of machine learning methods, the effectiveness and robustness of this model are assessed in noisy environments. A case study was conducted using the Tic-Tac-Toe game in a 3-by-3 grid environment, where the focus is to accurately identify the actions of the arms in selecting specific locations within this constrained environment. Experimental results show that our approach can achieve precise key point detection and action classification despite the addition of noise and uncertainties to the dataset.

Acoustic echo cancellation (AEC), noise suppression (NS) and dereverberation (DR) are an integral part of modern full-duplex communication systems. As the demand for teleconferencing systems increases, addressing these tasks is required for an effective and efficient online meeting experience. Most prior research proposes solutions for these tasks separately, combining them with digital signal processing (DSP) based components, resulting in complex pipelines that are often impractical to deploy in real-world applications. This paper proposes a real-time cross-attention deep model, named DeepVQE, based on residual convolutional neural networks (CNNs) and recurrent neural networks (RNNs) to simultaneously address AEC, NS, and DR. We conduct several ablation studies to analyze the contributions of different components of our model to the overall performance. DeepVQE achieves state-of-the-art performance on non-personalized tracks from the ICASSP 2023 Acoustic Echo Cancellation Challenge and ICASSP 2023 Deep Noise Suppression Challenge test sets, showing that a single model can handle multiple tasks with excellent performance. Moreover, the model runs in real-time and has been successfully tested for the Microsoft Teams platform.

Deep learning yields great results across many fields, from speech recognition, image classification, to translation. But for each problem, getting a deep model to work well involves research into the architecture and a long period of tuning. We present a single model that yields good results on a number of problems spanning multiple domains. In particular, this single model is trained concurrently on ImageNet, multiple translation tasks, image captioning (COCO dataset), a speech recognition corpus, and an English parsing task. Our model architecture incorporates building blocks from multiple domains. It contains convolutional layers, an attention mechanism, and sparsely-gated layers. Each of these computational blocks is crucial for a subset of the tasks we train on. Interestingly, even if a block is not crucial for a task, we observe that adding it never hurts performance and in most cases improves it on all tasks. We also show that tasks with less data benefit largely from joint training with other tasks, while performance on large tasks degrades only slightly if at all.

A soundscape is composed of three types of sound: biophony (sounds made by animals), geophony (natural abiotic sounds) and anthropophony (sounds made by humans). A key research question in the field of soundscape ecology is how these components interact with each other, specifically how biophony responds to geophony and anthropophony. Nevertheless, as of today, there are not many analytical instruments that enable the distinct quantification of these elements. Recent machine learning (ML) approaches aim to support automated analysis but often rely on task-specific or clean data, limiting generalisation to noisy passive acoustic monitoring (PAM) recordings. This study presents a clear and reproducible structure to build ML models for coarse soundscape classification and introduces CoarseSoundNet, a deep learning model trained to distinguish biophony, geophony, and anthropophony under realistic PAM conditions. We systematically investigate model architectures, the influence of an additional training class, data composition, and evaluation strategies. Our findings suggest that model performance improves with additional PAM data, especially when similar to the target domain, and by introducing an explicit silence class during training. Class-specific decision thresholds and duration-based constraints further enhance performance, particularly for anthropophony and geophony. Error analyses exhibit challenges for anthropophony due to masking effects and confusions for silence and insect sounds for geophony and biophony. Finally, we conduct an ecological case study which shows that pre-filtering recordings with CoarseSoundNet yields acoustic index trends comparable to ground-truth filtering, supporting its use as an effective preprocessing tool for ecoacoustic analyses.

Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides and specialized deep learning methods and models. Multiple self-supervised foundation feature extractors have been developed, enabling downstream predictive applications from cell segmentation to tumor sub-typing and survival analysis. In contrast, generative foundation models designed specifically for histopathology remain scarce. Such models could address tasks that are beyond the capabilities of feature extractors, such as virtual staining. In this paper, we introduce CytoSyn, a state-of-the-art foundation latent diffusion model that enables the guided generation of highly realistic and diverse histopathology H&E-stained images, as shown in an extensive benchmark. We explored methodological improvements, training set scaling, sampling strategies and slide-level overfitting, culminating in the improved CytoSyn-v2, and compared our work to PixCell, a state-of-the-art model, in an in-depth manner. This comparison highlighted the strong sensitivity of both diffusion models and performance metrics to preprocessing-specific details such as JPEG compression. Our model has been trained on a dataset obtained from more than 10,000 TCGA diagnostic whole-slide images of 32 different cancer types. Despite being trained only on oncology slides, it maintains state-of-the-art performance generating inflammatory bowel disease images. To support the research community, we publicly release CytoSyn's weights, its training and validation datasets, and a sample of synthetic images in this repository: https://huggingface.co/Owkin-Bioptimus/CytoSyn.

Accurate computational identification of DNA methylation is essential for understanding epigenetic regulation. Although deep learning excels in this binary classification task, its "black-box" nature impedes biological insight. We address this by introducing a high-performance model MEDNA-DFM, alongside mechanism-inspired signal purification algorithms. Our investigation demonstrates that MEDNA-DFM effectively captures conserved methylation patterns, achieving robust distinction across diverse species. Validation on external independent datasets confirms that the model's generalization is driven by conserved intrinsic motifs (e.g., GC content) rather than phylogenetic proximity. Furthermore, applying our developed algorithms extracted motifs with significantly higher reliability than prior studies. Finally, empirical evidence from a Drosophila 6mA case study prompted us to propose a "sequence-structure synergy" hypothesis, suggesting that the GAGG core motif and an upstream A-tract element function cooperatively. We further validated this hypothesis via in silico mutagenesis, confirming that the ablation of either or both elements significantly degrades the model's recognition capabilities. This work provides a powerful tool for methylation prediction and demonstrates how explainable deep learning can drive both methodological innovation and the generation of biological hypotheses.

During developmental processes such as embryogenesis, how a group of cells fold into specific structures, is a central question in biology that defines how living organisms form. Establishing tissue-level morphology critically relies on how every single cell decides to position itself relative to its neighboring cells. Despite its importance, it remains a major challenge to understand and predict the behavior of every cell within the living tissue over time during such intricate processes. To tackle this question, we propose a geometric deep learning model that can predict multicellular folding and embryogenesis, accurately capturing the highly convoluted spatial interactions among cells. We demonstrate that multicellular data can be represented with both granular and foam-like physical pictures through a unified graph data structure, considering both cellular interactions and cell junction networks. We successfully use our model to achieve two important tasks, interpretable 4-D morphological sequence alignment, and predicting local cell rearrangements before they occur at single-cell resolution. Furthermore, using an activation map and ablation studies, we demonstrate that cell geometries and cell junction networks together regulate local cell rearrangement which is critical for embryo morphogenesis. This approach provides a novel paradigm to study morphogenesis, highlighting a unified data structure and harnessing the power of geometric deep learning to accurately model the mechanisms and behaviors of cells during development. It offers a pathway toward creating a unified dynamic morphological atlas for a variety of developmental processes such as embryogenesis.

Active inference is a first principles approach for understanding the brain in particular, and sentient agents in general, with the single imperative of minimizing free energy. As such, it provides a computational account for modelling artificial intelligent agents, by defining the agent's generative model and inferring the model parameters, actions and hidden state beliefs. However, the exact specification of the generative model and the hidden state space structure is left to the experimenter, whose design choices influence the resulting behaviour of the agent. Recently, deep learning methods have been proposed to learn a hidden state space structure purely from data, alleviating the experimenter from this tedious design task, but resulting in an entangled, non-interpreteable state space. In this paper, we hypothesize that such a learnt, entangled state space does not necessarily yield the best model in terms of free energy, and that enforcing different factors in the state space can yield a lower model complexity. In particular, we consider the problem of 3D object representation, and focus on different instances of the ShapeNet dataset. We propose a model that factorizes object shape, pose and category, while still learning a representation for each factor using a deep neural network. We show that models, with best disentanglement properties, perform best when adopted by an active agent in reaching preferred observations.

Face anti-spoofing (FAS) aims at distinguishing face spoof attacks from the authentic ones, which is typically approached by learning proper models for performing the associated classification task. In practice, one would expect such models to be generalized to FAS in different image domains. Moreover, it is not practical to assume that the type of spoof attacks would be known in advance. In this paper, we propose a deep learning model for addressing the aforementioned domain-generalized face anti-spoofing task. In particular, our proposed network is able to disentangle facial liveness representation from the irrelevant ones (i.e., facial content and image domain features). The resulting liveness representation exhibits sufficient domain invariant properties, and thus it can be applied for performing domain-generalized FAS. In our experiments, we conduct experiments on five benchmark datasets with various settings, and we verify that our model performs favorably against state-of-the-art approaches in identifying novel types of spoof attacks in unseen image domains.

Blood vessels of the brain provide the human brain with the required nutrients and oxygen. As a vulnerable part of the cerebral blood supply, pathology of small vessels can cause serious problems such as Cerebral Small Vessel Diseases (CSVD). It has also been shown that CSVD is related to neurodegeneration, such as Alzheimer's disease. With the advancement of 7 Tesla MRI systems, higher spatial image resolution can be achieved, enabling the depiction of very small vessels in the brain. Non-Deep Learning-based approaches for vessel segmentation, e.g., Frangi's vessel enhancement with subsequent thresholding, are capable of segmenting medium to large vessels but often fail to segment small vessels. The sensitivity of these methods to small vessels can be increased by extensive parameter tuning or by manual corrections, albeit making them time-consuming, laborious, and not feasible for larger datasets. This paper proposes a deep learning architecture to automatically segment small vessels in 7 Tesla 3D Time-of-Flight (ToF) Magnetic Resonance Angiography (MRA) data. The algorithm was trained and evaluated on a small imperfect semi-automatically segmented dataset of only 11 subjects; using six for training, two for validation, and three for testing. The deep learning model based on U-Net Multi-Scale Supervision was trained using the training subset and was made equivariant to elastic deformations in a self-supervised manner using deformation-aware learning to improve the generalisation performance. The proposed technique was evaluated quantitatively and qualitatively against the test set and achieved a Dice score of 80.44 pm 0.83. Furthermore, the result of the proposed method was compared against a selected manually segmented region (62.07 resultant Dice) and has shown a considerable improvement (18.98\%) with deformation-aware learning.

Today, most newsreaders read the online version of news articles rather than traditional paper-based newspapers. Also, news media publishers rely heavily on the income generated from subscriptions and website visits made by newsreaders. Thus, online user engagement is a very important issue for online newspapers. Much effort has been spent on writing interesting headlines to catch the attention of online users. On the other hand, headlines should not be misleading (e.g., clickbaits); otherwise, readers would be disappointed when reading the content. In this paper, we propose four indicators to determine the quality of published news headlines based on their click count and dwell time, which are obtained by website log analysis. Then, we use soft target distribution of the calculated quality indicators to train our proposed deep learning model which can predict the quality of unpublished news headlines. The proposed model not only processes the latent features of both headline and body of the article to predict its headline quality but also considers the semantic relation between headline and body as well. To evaluate our model, we use a real dataset from a major Canadian newspaper. Results show our proposed model outperforms other state-of-the-art NLP models.

In a typical video conferencing setup, it is hard to maintain eye contact during a call since it requires looking into the camera rather than the display. We propose an eye contact correction model that restores the eye contact regardless of the relative position of the camera and display. Unlike previous solutions, our model redirects the gaze from an arbitrary direction to the center without requiring a redirection angle or camera/display/user geometry as inputs. We use a deep convolutional neural network that inputs a monocular image and produces a vector field and a brightness map to correct the gaze. We train this model in a bi-directional way on a large set of synthetically generated photorealistic images with perfect labels. The learned model is a robust eye contact corrector which also predicts the input gaze implicitly at no additional cost. Our system is primarily designed to improve the quality of video conferencing experience. Therefore, we use a set of control mechanisms to prevent creepy results and to ensure a smooth and natural video conferencing experience. The entire eye contact correction system runs end-to-end in real-time on a commodity CPU and does not require any dedicated hardware, making our solution feasible for a variety of devices.

Humans prove theorems by relying on substantial high-level reasoning and problem-specific insights. Proof assistants offer a formalism that resembles human mathematical reasoning, representing theorems in higher-order logic and proofs as high-level tactics. However, human experts have to construct proofs manually by entering tactics into the proof assistant. In this paper, we study the problem of using machine learning to automate the interaction with proof assistants. We construct CoqGym, a large-scale dataset and learning environment containing 71K human-written proofs from 123 projects developed with the Coq proof assistant. We develop ASTactic, a deep learning-based model that generates tactics as programs in the form of abstract syntax trees (ASTs). Experiments show that ASTactic trained on CoqGym can generate effective tactics and can be used to prove new theorems not previously provable by automated methods. Code is available at https://github.com/princeton-vl/CoqGym.

Click-through rate~(CTR) prediction, whose goal is to estimate the probability of the user clicks, has become one of the core tasks in advertising systems. For CTR prediction model, it is necessary to capture the latent user interest behind the user behavior data. Besides, considering the changing of the external environment and the internal cognition, user interest evolves over time dynamically. There are several CTR prediction methods for interest modeling, while most of them regard the representation of behavior as the interest directly, and lack specially modeling for latent interest behind the concrete behavior. Moreover, few work consider the changing trend of interest. In this paper, we propose a novel model, named Deep Interest Evolution Network~(DIEN), for CTR prediction. Specifically, we design interest extractor layer to capture temporal interests from history behavior sequence. At this layer, we introduce an auxiliary loss to supervise interest extracting at each step. As user interests are diverse, especially in the e-commerce system, we propose interest evolving layer to capture interest evolving process that is relative to the target item. At interest evolving layer, attention mechanism is embedded into the sequential structure novelly, and the effects of relative interests are strengthened during interest evolution. In the experiments on both public and industrial datasets, DIEN significantly outperforms the state-of-the-art solutions. Notably, DIEN has been deployed in the display advertisement system of Taobao, and obtained 20.7\% improvement on CTR.

We develop a large-scale deep learning model to predict price movements from limit order book (LOB) data of cash equities. The architecture utilises convolutional filters to capture the spatial structure of the limit order books as well as LSTM modules to capture longer time dependencies. The proposed network outperforms all existing state-of-the-art algorithms on the benchmark LOB dataset [1]. In a more realistic setting, we test our model by using one year market quotes from the London Stock Exchange and the model delivers a remarkably stable out-of-sample prediction accuracy for a variety of instruments. Importantly, our model translates well to instruments which were not part of the training set, indicating the model's ability to extract universal features. In order to better understand these features and to go beyond a "black box" model, we perform a sensitivity analysis to understand the rationale behind the model predictions and reveal the components of LOBs that are most relevant. The ability to extract robust features which translate well to other instruments is an important property of our model which has many other applications.

Large scale deep learning model, such as modern language models and diffusion architectures, have revolutionized applications ranging from natural language processing to computer vision. However, their deployment in distributed or decentralized environments raises significant privacy concerns, as sensitive data may be exposed during inference. Traditional techniques like secure multi-party computation, homomorphic encryption, and differential privacy offer partial remedies but often incur substantial computational overhead, latency penalties, or limited compatibility with non-linear network operations. In this work, we introduce Equivariant Encryption (EE), a novel paradigm designed to enable secure, "blind" inference on encrypted data with near zero performance overhead. Unlike fully homomorphic approaches that encrypt the entire computational graph, EE selectively obfuscates critical internal representations within neural network layers while preserving the exact functionality of both linear and a prescribed set of non-linear operations. This targeted encryption ensures that raw inputs, intermediate activations, and outputs remain confidential, even when processed on untrusted infrastructure. We detail the theoretical foundations of EE, compare its performance and integration complexity against conventional privacy preserving techniques, and demonstrate its applicability across a range of architectures, from convolutional networks to large language models. Furthermore, our work provides a comprehensive threat analysis, outlining potential attack vectors and baseline strategies, and benchmarks EE against standard inference pipelines in decentralized settings. The results confirm that EE maintains high fidelity and throughput, effectively bridging the gap between robust data confidentiality and the stringent efficiency requirements of modern, large scale model inference.

Definition Extraction (DE) is one of the well-known topics in Information Extraction that aims to identify terms and their corresponding definitions in unstructured texts. This task can be formalized either as a sentence classification task (i.e., containing term-definition pairs or not) or a sequential labeling task (i.e., identifying the boundaries of the terms and definitions). The previous works for DE have only focused on one of the two approaches, failing to model the inter-dependencies between the two tasks. In this work, we propose a novel model for DE that simultaneously performs the two tasks in a single framework to benefit from their inter-dependencies. Our model features deep learning architectures to exploit the global structures of the input sentences as well as the semantic consistencies between the terms and the definitions, thereby improving the quality of the representation vectors for DE. Besides the joint inference between sentence classification and sequential labeling, the proposed model is fundamentally different from the prior work for DE in that the prior work has only employed the local structures of the input sentences (i.e., word-to-word relations), and not yet considered the semantic consistencies between terms and definitions. In order to implement these novel ideas, our model presents a multi-task learning framework that employs graph convolutional neural networks and predicts the dependency paths between the terms and the definitions. We also seek to enforce the consistency between the representations of the terms and definitions both globally (i.e., increasing semantic consistency between the representations of the entire sentences and the terms/definitions) and locally (i.e., promoting the similarity between the representations of the terms and the definitions).

With the global refugee crisis at a historic high, there is a growing need to assess the impact of refugee settlements on their hosting countries and surrounding environments. Because fires are an important land management practice in smallholder agriculture in sub-Saharan Africa, burned area (BA) mappings can help provide information about the impacts of land management practices on local environments. However, a lack of BA ground-truth data in much of sub-Saharan Africa limits the use of highly scalable deep learning (DL) techniques for such BA mappings. In this work, we propose a scalable transfer learning approach to study BA dynamics in areas with little to no ground-truth data such as the West Nile region in Northern Uganda. We train a deep learning model on BA ground-truth data in Portugal and propose the application of that model on refugee-hosting districts in West Nile between 2015 and 2020. By comparing the district-level BA dynamic with the wider West Nile region, we aim to add understanding of the land management impacts of refugee settlements on their surrounding environments.

Distributed Acoustic Sensing (DAS) is an emerging technology for earthquake monitoring and subsurface imaging. The recorded seismic signals by DAS have several distinct characteristics, such as unknown coupling effects, strong anthropogenic noise, and ultra-dense spatial sampling. These aspects differ from conventional seismic data recorded by seismic networks, making it challenging to utilize DAS at present for seismic monitoring. New data analysis algorithms are needed to extract useful information from DAS data. Previous studies on conventional seismic data demonstrated that deep learning models could achieve performance close to human analysts in picking seismic phases. However, phase picking on DAS data is still a difficult problem due to the lack of manual labels. Further, the differences in mathematical structure between these two data formats, i.e., ultra-dense DAS arrays and sparse seismic networks, make model fine-tuning or transfer learning difficult to implement on DAS data. In this work, we design a new approach using semi-supervised learning to solve the phase-picking task on DAS arrays. We use a pre-trained PhaseNet model as a teacher network to generate noisy labels of P and S arrivals on DAS data and apply the Gaussian mixture model phase association (GaMMA) method to refine these noisy labels to build training datasets. We develop a new deep learning model, PhaseNet-DAS, to process the 2D spatial-temporal data of DAS arrays and train the model on DAS data. The new deep learning model achieves high picking accuracy and good earthquake detection performance. We then apply the model to process continuous data and build earthquake catalogs directly from DAS recording. Our approach using semi-supervised learning provides a way to build effective deep learning models for DAS, which have the potential to improve earthquake monitoring using large-scale fiber networks.

Stochastic gradient descent method and its variants constitute the core optimization algorithms that achieve good convergence rates for solving machine learning problems. These rates are obtained especially when these algorithms are fine-tuned for the application at hand. Although this tuning process can require large computational costs, recent work has shown that these costs can be reduced by line search methods that iteratively adjust the stepsize. We propose an alternative approach to stochastic line search by using a new algorithm based on forward step model building. This model building step incorporates second-order information that allows adjusting not only the stepsize but also the search direction. Noting that deep learning model parameters come in groups (layers of tensors), our method builds its model and calculates a new step for each parameter group. This novel diagonalization approach makes the selected step lengths adaptive. We provide convergence rate analysis, and experimentally show that the proposed algorithm achieves faster convergence and better generalization in well-known test problems. More precisely, SMB requires less tuning, and shows comparable performance to other adaptive methods.

Word emphasis in textual content aims at conveying the desired intention by changing the size, color, typeface, style (bold, italic, etc.), and other typographical features. The emphasized words are extremely helpful in drawing the readers' attention to specific information that the authors wish to emphasize. However, performing such emphasis using a soft keyboard for social media interactions is time-consuming and has an associated learning curve. In this paper, we propose a novel approach to automate the emphasis word detection on short written texts. To the best of our knowledge, this work presents the first lightweight deep learning approach for smartphone deployment of emphasis selection. Experimental results show that our approach achieves comparable accuracy at a much lower model size than existing models. Our best lightweight model has a memory footprint of 2.82 MB with a matching score of 0.716 on SemEval-2020 public benchmark dataset.