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0 | NCT07661732 | title | 1 | NCT07661732_1 | trial_topic_question | What is the focus of the ELITE-HFpEF study? | eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF Randomized Trial Of A Digital Lifestyle Education Strategy In Patients With Heart Failure And Overweight Or Obesity: The ELITE-HFpEF Study | 198 | d08b7d5b9810dc265979e5d3031190f66ac14fc9a8e315e23f3d6a578ac0d2d0 | success |
1 | NCT07661732 | summary | 2 | NCT07661732_2 | study_objective_question | Is there evidence that a digital lifestyle education program improves exercise capacity in adults with heart failure with preserved ejection fraction? | The goal of this clinical trial is to learn if a digital lifestyle education program improves exercise capacity in adults who have heart failure with preserved ejection fraction (HFpEF) and overweight or obesity. HFpEF is a type of heart failure in which the heart muscle is stiff and does not relax well, even though it... | 1,202 | e4e312b512120909e8d2af05c7e4ca6624ee2f2787c82161cb7468e44e9b5a2b | success |
2 | NCT07661732 | summary | 2 | NCT07661732_2 | clinical_population_question | Are overweight or obese adults with heart failure with preserved ejection fraction being recruited for this clinical trial? | The goal of this clinical trial is to learn if a digital lifestyle education program improves exercise capacity in adults who have heart failure with preserved ejection fraction (HFpEF) and overweight or obesity. HFpEF is a type of heart failure in which the heart muscle is stiff and does not relax well, even though it... | 1,202 | e4e312b512120909e8d2af05c7e4ca6624ee2f2787c82161cb7468e44e9b5a2b | success |
3 | NCT07661732 | inclusion_criteria | 3 | NCT07661732_3 | patient_profile_question | What are the symptoms consistent with heart failure in this trial? | * Age over 18 years
* Body mass index (BMI) over 27 kg/m²
* Symptoms consistent with heart failure
* Left ventricular ejection fraction (LVEF) of 50% or higher
* Elevated NT-proBNP according to the European Society of Cardiology age-adjusted rule-in thresholds: 125 pg/mL or higher if under 50 years, 250 pg/mL or higher... | 501 | 3ca3b2b2bd1be031044984f628e17bb566c6f527061a324fe5bbf389d58e4652 | success |
4 | NCT07661732 | inclusion_criteria | 3 | NCT07661732_3 | eligibility_constraint_question | What is the minimum BMI required for inclusion in this clinical trial? | * Age over 18 years
* Body mass index (BMI) over 27 kg/m²
* Symptoms consistent with heart failure
* Left ventricular ejection fraction (LVEF) of 50% or higher
* Elevated NT-proBNP according to the European Society of Cardiology age-adjusted rule-in thresholds: 125 pg/mL or higher if under 50 years, 250 pg/mL or higher... | 501 | 3ca3b2b2bd1be031044984f628e17bb566c6f527061a324fe5bbf389d58e4652 | success |
5 | NCT07704034 | title | 1 | NCT07704034_1 | trial_topic_question | What is the focus of this clinical trial? | Wearable-Triggered Digital Safety Net for Real-Time Monitoring and Intervention in Leptomeningeal Metastasis | 108 | 8f1e1bde5e487d1aadc4af2ba31319921d9ea0932dc8619afc67b66922aab95a | success |
6 | NCT07704034 | inclusion_criteria | 3 | NCT07704034_3 | patient_profile_question | What is the specific type of metastasis that participants must have? | * Participants must have leptomeningeal metastasis (LMM) diagnosed per clinical, imaging, and/or CSF/cytology criteria (cytology, flow cytometry, or circulating tumor DNA), arising from any solid or hematologic tumor primary.
* Participants must be undergoing active anti-cancer therapy (systemic, intrathecal, and/or ra... | 1,159 | 9e18c8a554c89d6cdb998499fb73940fd8097c918b4a703124c00344db7a9635 | success |
7 | NCT07704034 | inclusion_criteria | 3 | NCT07704034_3 | eligibility_constraint_question | What is the minimum age requirement for study enrollment? | * Participants must have leptomeningeal metastasis (LMM) diagnosed per clinical, imaging, and/or CSF/cytology criteria (cytology, flow cytometry, or circulating tumor DNA), arising from any solid or hematologic tumor primary.
* Participants must be undergoing active anti-cancer therapy (systemic, intrathecal, and/or ra... | 1,159 | 9e18c8a554c89d6cdb998499fb73940fd8097c918b4a703124c00344db7a9635 | success |
8 | NCT07704034 | summary | 2 | NCT07704034_2 | study_objective_question | Is this clinical trial investigating the use of consumer Smartwatches for monitoring health in patients with leptomeningeal metastasis? | This research study is for participants diagnosed with leptomeningeal metastasis disease (LMM), a condition where cancer has spread to the fluid and membranes surround the brain and spinal cord. The purpose of this study is to find out whether a consumer Smartwatch can continuously monitor the participant's health and ... | 515 | 7fd34c5543eff871725a7df99e11051bed92afc42ffcc2154bfbf1ed981c011f | success |
9 | NCT07704034 | summary | 2 | NCT07704034_2 | clinical_population_question | Who are the participants being recruited for this clinical trial, specifically those diagnosed with leptomeningeal metastasis disease? | This research study is for participants diagnosed with leptomeningeal metastasis disease (LMM), a condition where cancer has spread to the fluid and membranes surround the brain and spinal cord. The purpose of this study is to find out whether a consumer Smartwatch can continuously monitor the participant's health and ... | 515 | 7fd34c5543eff871725a7df99e11051bed92afc42ffcc2154bfbf1ed981c011f | success |
10 | NCT07698509 | title | 1 | NCT07698509_1 | trial_topic_question | What is the focus of this clinical trial? | Virtual Lifestyle Medicine Group Visits for High Blood Pressure A Scalable, Lifestyle Medicine Intervention for Hypertension Using Virtual Group Shared Medical Appointments | 172 | b078c8474731ff7351485144fdcc3882e1e7674db8d7bdebb8552399a7dcd906 | success |
11 | NCT07698509 | summary | 2 | NCT07698509_2 | clinical_population_question | Who is the target population for this virtual Lifestyle medicine shared medical appointments study? | The purpose of this study is to learn whether virtual Lifestyle medicine shared medical appointments (LMSMAs) can help people better manage their blood pressure and improve their overall health. | 194 | 9afa9188885bd538c7595651e2dd44187bb3be6f67f1ca03012dac4d47eee2f3 | success |
12 | NCT07698509 | inclusion_criteria | 3 | NCT07698509_3 | patient_profile_question | What is the current diagnosis of hypertension for this clinical trial? | * Current diagnosis of hypertension (ICD codes I10.0-I14.0 billed within the last 5 years Essential HTN, Essential HTN, Primary HTN)
* Currently receives care at a UTPhysicians; Last seen by a PCP at Victory location within the last 1 year.
* Able to participate in a virtual format
* Willingness to participate and enga... | 358 | 1988ae491d7ef0fb63644d62eafae16c7f5c7e26e45ea89ff15ad96ff5cbf6fb | success |
13 | NCT07698509 | inclusion_criteria | 3 | NCT07698509_3 | eligibility_constraint_question | Must participants have received care at a UTPhysicians within the last year? | * Current diagnosis of hypertension (ICD codes I10.0-I14.0 billed within the last 5 years Essential HTN, Essential HTN, Primary HTN)
* Currently receives care at a UTPhysicians; Last seen by a PCP at Victory location within the last 1 year.
* Able to participate in a virtual format
* Willingness to participate and enga... | 358 | 1988ae491d7ef0fb63644d62eafae16c7f5c7e26e45ea89ff15ad96ff5cbf6fb | success |
14 | NCT07637097 | title | 1 | NCT07637097_1 | trial_topic_question | What is the focus of this clinical trial? | VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body Dementia Reducing Depression in Family Caregivers of Persons Living With Lewy Body Dementia Through Tailored Asynchronous Online Intervention. | 214 | d18761eeebddef6b9c9509752dbaffc1b22286a9d81371f56905c7901e4d328d | success |
15 | NCT07637097 | summary | 2 | NCT07637097_2 | clinical_population_question | Who are the family caregivers being targeted in this study? | This study tests whether a tailored, fully asynchronous online group intervention (VOCALE LBD) reduces depression in family caregivers of people with Lewy Body Dementia (LBD), compared to standard educational materials. LBD is the second most common form of degenerative dementia and causes distinct challenges, includin... | 1,337 | 408ec8e976f14317b8149094539dbd38168549c7dcfecf442c81baf9081e208d | success |
16 | NCT07637097 | inclusion_criteria | 3 | NCT07637097_3 | patient_profile_question | Who has a confirmed diagnosis of Lewy Body Dementia (LBD) or LBD mixed pathology? | * Current family member or informal (unpaid) caregiver of a person with a confirmed diagnosis of Lewy Body Dementia (LBD) or LBD mixed pathology
* Experiences depressive symptoms as defined by a score of 5 or higher on the Patient Health Questionnaire-9 (PHQ-9)
* Able to read, write, and speak English
* Has access to a... | 488 | 874051ac9a49833db9775129a47f11e8a362ce9354085a982dc10e19c289509f | success |
17 | NCT07637097 | inclusion_criteria | 3 | NCT07637097_3 | eligibility_constraint_question | What is the minimum score on the Patient Health Questionnaire-9 (PHQ-9) for a caregiver to be eligible? | * Current family member or informal (unpaid) caregiver of a person with a confirmed diagnosis of Lewy Body Dementia (LBD) or LBD mixed pathology
* Experiences depressive symptoms as defined by a score of 5 or higher on the Patient Health Questionnaire-9 (PHQ-9)
* Able to read, write, and speak English
* Has access to a... | 488 | 874051ac9a49833db9775129a47f11e8a362ce9354085a982dc10e19c289509f | success |
18 | NCT07717671 | title | 1 | NCT07717671_1 | trial_topic_question | What is the focus of the VIPPSTAR-G1 clinical trial? | VIPPSTAR-G1 Digital Early Intervention for Visual Impairment VIPPSTAR-G1: A Multicenter Randomized Controlled Trial Evaluating a Caregiver-mediated Digital Intervention to Promote Visual Function and Neurodevelopment in Infants at Risk of/With Visual Impairment | 261 | 49899359709950ab8c0253ea496f26f43ee86d26509011951cda54255b2c9e7e | success |
19 | NCT07717671 | summary | 2 | NCT07717671_2 | clinical_population_question | Who are the participants at risk of or with visual impairment being targeted in the VIPPSTAR-G1 study? | Visual impairment in infancy is associated with significant risks for neurodevelopmental impairment. Early intervention based on enriched visual and multisensory experiences may promote neuroplasticity and improve developmental outcomes, but implementation of intensive interventions in routine clinical practice remains... | 1,260 | 59babb5c86e3d671d1d8748cb542ca4cbfbdab5242f204ef5ceed7e611997bd4 | success |
20 | NCT07717671 | inclusion_criteria | 3 | NCT07717671_3 | patient_profile_question | What is the typical gestational age of patients in this trial? | * Gestational age ≤32 weeks OR full-term/newborns\>32 weeks of age with neonatal distress (Apgar ≤5 at 10 minutes)
* NAVEG score ≥3
* At least one neurological or neuroimaging abnormality:
* 3 abnormal signs at ATNAT neurological examination OR Abnormal cranial ultrasound findings OR Abnormal MRI findings
* Age ≤42 ... | 382 | 822de48868e5737606b84d1796af999d8ee20eaf7f0eb486ba8a8e9f44d80ef6 | success |
21 | NCT07717671 | inclusion_criteria | 3 | NCT07717671_3 | eligibility_constraint_question | Are patients with a NAVEG score less than 3 eligible for this trial? | * Gestational age ≤32 weeks OR full-term/newborns\>32 weeks of age with neonatal distress (Apgar ≤5 at 10 minutes)
* NAVEG score ≥3
* At least one neurological or neuroimaging abnormality:
* 3 abnormal signs at ATNAT neurological examination OR Abnormal cranial ultrasound findings OR Abnormal MRI findings
* Age ≤42 ... | 382 | 822de48868e5737606b84d1796af999d8ee20eaf7f0eb486ba8a8e9f44d80ef6 | success |
22 | NCT07738224 | title | 1 | NCT07738224_1 | trial_topic_question | What is the focus of this clinical trial? | Using the Babble Boot Camp© Speech Therapy Approach With Babies Born Prematurely Babble Boot Camp© for Preterm Infants: A Trial of a Proactive Speech/Language Intervention | 171 | c11fe7e765449beec8fffafa57eda8fff86c941d61956771d251d8322405a192 | success |
23 | NCT07738224 | summary | 2 | NCT07738224_2 | study_objective_question | What speech therapy intervention is being evaluated for its effectiveness in supporting early communication in preterm infants? | Babble Boot Camp focuses on early speech and language development, environmental enrichment and supporting parent-infant interaction with the aim of improving communication outcomes and parental well-being in at risk children.
The goal of this clinical trial is to learn if this parent-coaching speech therapy intervent... | 1,182 | 1f57bbebc491ba6120a1a0d3212533569e957298e8c4952ff05446f74d397fff | success |
24 | NCT07738224 | inclusion_criteria | 3 | NCT07738224_3 | patient_profile_question | What is the gestational age criterion for infant participants? | * Infants born \<32 weeks' gestational age (GA)
* Infants medically stable and not ventilator dependent at recruitment
* Primary language spoken at home is English
* Participants able to attend 6 months of telehealth early intervention
* Infants less than 5.5 months corrected age
| 282 | ef6346341a5b480c3a3d53071dfcfd257a5c32a6e04f1d748cdc310c74d1e068 | success |
25 | NCT07738224 | inclusion_criteria | 3 | NCT07738224_3 | eligibility_constraint_question | Is English proficiency a requirement for telehealth early intervention? | * Infants born \<32 weeks' gestational age (GA)
* Infants medically stable and not ventilator dependent at recruitment
* Primary language spoken at home is English
* Participants able to attend 6 months of telehealth early intervention
* Infants less than 5.5 months corrected age
| 282 | ef6346341a5b480c3a3d53071dfcfd257a5c32a6e04f1d748cdc310c74d1e068 | success |
26 | NCT07751458 | title | 1 | NCT07751458_1 | trial_topic_question | What is the focus of the WISE Study? | The WISE Study (WhatsApp Intervention for Sleep in the Elderly) The WISE Study (WhatsApp Intervention for Sleep in the Elderly): Targeting Insomnia and Loneliness With a Digital Booklet | 185 | 60b97f6685327928cd101f898fc3c6cfb4495052fb1103bc90658a25eab01b6a | success |
27 | NCT07751458 | summary | 2 | NCT07751458_2 | study_objective_question | What is being studied in this clinical trial? | Sleep hygiene education is an educational effort to teach healthy sleep habits and behaviors to improve sleep quality, duration, and regularity naturally without the use of medication; however, this approach has not been established in Indonesia. This study aims to establish a sleep hygiene education care model among l... | 1,514 | 50760d5f34206056a70babcb8528f211e05707e524e2c28178609cf8d00c50ed | success |
28 | NCT07751458 | summary | 2 | NCT07751458_2 | clinical_population_question | Who are the participants targeted by this study? | Sleep hygiene education is an educational effort to teach healthy sleep habits and behaviors to improve sleep quality, duration, and regularity naturally without the use of medication; however, this approach has not been established in Indonesia. This study aims to establish a sleep hygiene education care model among l... | 1,514 | 50760d5f34206056a70babcb8528f211e05707e524e2c28178609cf8d00c50ed | success |
29 | NCT07751458 | inclusion_criteria | 3 | NCT07751458_3 | patient_profile_question | What is the primary clinical phenotype of interest in this trial? | * Elderly individuals diagnosed with loneliness
* Reported experiencing sleep disturbances in the past 2 weeks, either continuously or intermittently
* Experiencing insomnia with a total score of ≥ 8 on the Indonesian version of the Insomnia Severity Index (ISI) during screening
* Able to communicate in Indonesian
| 317 | 469f1a88cb084bd0c08d9c050f62214918c05760602fcf0cc3e1408f894587df | success |
30 | NCT07751458 | inclusion_criteria | 3 | NCT07751458_3 | eligibility_constraint_question | What is the minimum score on the Indonesian version of the Insomnia Severity Index required for eligibility? | * Elderly individuals diagnosed with loneliness
* Reported experiencing sleep disturbances in the past 2 weeks, either continuously or intermittently
* Experiencing insomnia with a total score of ≥ 8 on the Indonesian version of the Insomnia Severity Index (ISI) during screening
* Able to communicate in Indonesian
| 317 | 469f1a88cb084bd0c08d9c050f62214918c05760602fcf0cc3e1408f894587df | success |
31 | NCT07711301 | title | 1 | NCT07711301_1 | trial_topic_question | What is the focus of The Science Tooth Fairy clinical trial? | The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting Tooth Book Evaluation | 171 | e8c689a3180f95a9d8f92ddf0c4a7b4a3b56f3a83ff5739a12ae7dd23d9137ca | success |
32 | NCT07711301 | summary | 2 | NCT07711301_2 | study_objective_question | What is being studied in this clinical trial? | Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development. While donating baby teeth to scientific research is painless and simple, researchers often face challenges collecting them. Past studies show that donatio... | 3,101 | 38e46cee7b8a1a8fd9c936dba53baff1286f4733b84e46d191753969138835c5 | success |
33 | NCT07711301 | summary | 2 | NCT07711301_2 | clinical_population_question | Who are the participants in this study, and what is their age range? | Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development. While donating baby teeth to scientific research is painless and simple, researchers often face challenges collecting them. Past studies show that donatio... | 3,101 | 38e46cee7b8a1a8fd9c936dba53baff1286f4733b84e46d191753969138835c5 | success |
34 | NCT07711301 | inclusion_criteria | 3 | NCT07711301_3 | patient_profile_question | What is the age range for the children participating in this clinical trial? | * Biological or non-biological parents (e.g., legal caregivers or guardians) of children aged 4-10 years
| 106 | c3b5edd88ecfd24732e33997abb182d0a4e69f68de8fa42cc56fa1a1e8310feb | success |
35 | NCT07711301 | inclusion_criteria | 3 | NCT07711301_3 | eligibility_constraint_question | Are biological parents eligible to participate in this clinical trial? | * Biological or non-biological parents (e.g., legal caregivers or guardians) of children aged 4-10 years
| 106 | c3b5edd88ecfd24732e33997abb182d0a4e69f68de8fa42cc56fa1a1e8310feb | success |
36 | NCT07690605 | title | 1 | NCT07690605_1 | trial_topic_question | What is the focus of this clinical trial? | The Genomic and Well-Being Impacts of an Extraverted Behavior Intervention | 74 | e66af89c57a4d56659d8425266d78c11919acf056931a9779df21ae74bfaac53 | success |
37 | NCT07690605 | summary | 2 | NCT07690605_2 | clinical_population_question | Who are the participants in this study, and what is their focus? | 8-week randomized intervention (with 3-month follow-up) that examines the impact of increased sociable behavior on emotional well-being and immune health profile | 161 | 141e9b5c6b7b0d2607af85e83bafce5fcbfaf1129c4aa6f5053e8c3085490532 | success |
38 | NCT07690605 | inclusion_criteria | 3 | NCT07690605_3 | patient_profile_question | What is the minimum age requirement for trial participants? | * Age 18 or older
| 19 | 87e817eca50c9e90a2923918b9d0c49897f17b62248a289e1ae164e3c84c9dd4 | success |
39 | NCT07690605 | inclusion_criteria | 3 | NCT07690605_3 | eligibility_constraint_question | Is there an upper age limit for patients to be eligible for this clinical trial? | * Age 18 or older
| 19 | 87e817eca50c9e90a2923918b9d0c49897f17b62248a289e1ae164e3c84c9dd4 | success |
40 | NCT07755631 | title | 1 | NCT07755631_1 | trial_topic_question | What is the focus of the BASIC-S Feasibility Study? | The BASIC-S Feasibility Study for Vascular Risk Reduction Piloting an Integrated Lifestyle Intervention for Vascular Risk Reduction: The BASIC-S Feasibility Study | 162 | f3b1971b88906d275d18b295471c8b794730e22ab6e7f47eb6a2812f07ef747b | success |
41 | NCT07755631 | summary | 2 | NCT07755631_2 | study_objective_question | What lifestyle changes is this study evaluating for reducing vascular risk factors? | Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging. To address this, we developed the BASIC-S framework, targeting Blood pressure, Activity, Sleep, Interaction (socially), Consumption (nutrition), and Support using partner... | 1,051 | 7a5a191f72b8118e1f068238f389fc5cb9196b19cc156a7610af55deed0c7332 | success |
42 | NCT07755631 | summary | 2 | NCT07755631_2 | clinical_population_question | Who are the participants in this cluster-randomized pilot trial? | Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging. To address this, we developed the BASIC-S framework, targeting Blood pressure, Activity, Sleep, Interaction (socially), Consumption (nutrition), and Support using partner... | 1,051 | 7a5a191f72b8118e1f068238f389fc5cb9196b19cc156a7610af55deed0c7332 | success |
43 | NCT07755631 | inclusion_criteria | 3 | NCT07755631_3 | patient_profile_question | Are participants in this clinical trial healthcare workers? | * Adults aged 18 years and older currently employed at or recently retired from the London Health Sciences Centre (LHSC) or Western University (with an operational focus on pre-retirees aged 50 years and older).
* Spouse or cohabitating partner of an enrolled primary participant (partner enrollment is optional but stro... | 566 | e9a1a31395ef6c1d04f4916ffd90733fb3baf6e1d74c5ae30c117af1f460f79e | success |
44 | NCT07755631 | inclusion_criteria | 3 | NCT07755631_3 | eligibility_constraint_question | Is age a requirement for enrolling in this study? | * Adults aged 18 years and older currently employed at or recently retired from the London Health Sciences Centre (LHSC) or Western University (with an operational focus on pre-retirees aged 50 years and older).
* Spouse or cohabitating partner of an enrolled primary participant (partner enrollment is optional but stro... | 566 | e9a1a31395ef6c1d04f4916ffd90733fb3baf6e1d74c5ae30c117af1f460f79e | success |
45 | NCT07666139 | title | 1 | NCT07666139_1 | trial_topic_question | What is the focus of the CARES Study? | The 'Comprehensive Adherence Resource and Empowerment Support' (CARES) Study Adapting the 'Comprehensive Adherence Resource and Empowerment Support' Intervention for Multiple PrEP Methods Among Adolescent Girls and Young Women in South Africa and Zimbabwe | 255 | 2342f29e6ca64a2257a72a433c1fcced26980c1276138c0f714a07bd0f939085 | success |
46 | NCT07666139 | summary | 2 | NCT07666139_2 | study_objective_question | What is being studied in this clinical trial? | The primary aim of this study is to adapt the Comprehensive Adherence Resource and Empowerment Support (CARES) intervention to support adolescent girls and young women (AGYW) aged 16-24 in Zimbabwe and South Africa in effectively using various forms of pre-exposure prophylaxis (PrEP), specifically oral, ring, and injec... | 1,154 | 6af49faab00ad5f1f5cf6fceef5c1672e1a5af0eeb4e4388928789badfc044d0 | success |
47 | NCT07666139 | summary | 2 | NCT07666139_2 | clinical_population_question | Who is the target population for this study? | The primary aim of this study is to adapt the Comprehensive Adherence Resource and Empowerment Support (CARES) intervention to support adolescent girls and young women (AGYW) aged 16-24 in Zimbabwe and South Africa in effectively using various forms of pre-exposure prophylaxis (PrEP), specifically oral, ring, and injec... | 1,154 | 6af49faab00ad5f1f5cf6fceef5c1672e1a5af0eeb4e4388928789badfc044d0 | success |
48 | NCT07666139 | inclusion_criteria | 3 | NCT07666139_3 | patient_profile_question | What age group is targeted in this clinical trial? | Aim 2:
Inclusion (AGYW):
* age 16-24 years (in Zimbabwe, participants aged 16 to 17 years must meet the legal criteria for emancipation to be eligible)
* has initiated PrEP during the study, or no more than 6 months before the study initiation date (for LEN PrEP), or no more than 3 months before the study initiation ... | 658 | 76fd53b8b53fdc586ae18352352b4d7d3dcbad72b1814c42514ae0f79bb11f9a | success |
49 | NCT07666139 | inclusion_criteria | 3 | NCT07666139_3 | eligibility_constraint_question | What are the requirements for participants who have initiated PrEP before the study initiation date? | Aim 2:
Inclusion (AGYW):
* age 16-24 years (in Zimbabwe, participants aged 16 to 17 years must meet the legal criteria for emancipation to be eligible)
* has initiated PrEP during the study, or no more than 6 months before the study initiation date (for LEN PrEP), or no more than 3 months before the study initiation ... | 658 | 76fd53b8b53fdc586ae18352352b4d7d3dcbad72b1814c42514ae0f79bb11f9a | success |
50 | NCT07695818 | title | 1 | NCT07695818_1 | trial_topic_question | What is the focus of this clinical trial? | Testing and Evaluation of the Returning to the Land Intervention to Address and Prevent Substance Misuse | 104 | 36aa3b9d245abc3dd06a177b7be1ac5fb0052e6f63f0430addd9d9ad765d03c4 | success |
51 | NCT07695818 | summary | 2 | NCT07695818_2 | clinical_population_question | Who is the target population for this study? | This study aims to test the Returning to the Land intervention in partnership with a tribal community. The program is designed to address caregiver substance use and child emotional and behavioral development. | 209 | 42bdb8d8391054410fbf5750b31bf5d840690161d2b432bb628cdda550b96433 | success |
52 | NCT07695818 | inclusion_criteria | 3 | NCT07695818_3 | patient_profile_question | What is the age range of eligible participants in this clinical trial? | * Reside on or near the Rocky Boy Reservation (\~50-mile round trip);
* Aged 14-19 years;
* Parent or primary caregiver to at least one child who will be age 1-5 years at the start of the intervention.
| 203 | 40efe526612cd1d8e8804bf7cf77145d777f764833841416e2c39da74ef91252 | success |
53 | NCT07695818 | inclusion_criteria | 3 | NCT07695818_3 | eligibility_constraint_question | Do participants need to reside on or near the Rocky Boy Reservation to be eligible for this study? | * Reside on or near the Rocky Boy Reservation (\~50-mile round trip);
* Aged 14-19 years;
* Parent or primary caregiver to at least one child who will be age 1-5 years at the start of the intervention.
| 203 | 40efe526612cd1d8e8804bf7cf77145d777f764833841416e2c39da74ef91252 | success |
54 | NCT07748780 | title | 1 | NCT07748780_1 | trial_topic_question | What is the focus of this clinical trial? | Testing a Blended Social-Communication and Social-Emotional Intervention for Autistic Toddlers | 94 | aa5150c1908e3e2ff8c75920b41e72ac58ffc764e5ccaf008ae86dea4f781e14 | success |
55 | NCT07748780 | summary | 2 | NCT07748780_2 | clinical_population_question | What population of autistic toddlers is targeted by this study? | Autistic toddlers often need support to develop both social-communication and social-emotional skills. Social communication (such as making requests or sharing attention) is usually addressed in early intervention, but social-emotional needs (such as expressing feelings or learning to cope with frustration) are often o... | 1,448 | dbfdfe652f0857db27b3c8fe0e504b0951dccca0df349e06a018c38252ea14ea | success |
56 | NCT07748780 | inclusion_criteria | 3 | NCT07748780_3 | patient_profile_question | What is the age criterion for participants? | * Under 36 months of age at enrollment.
* Has a clinical diagnosis of autism.
* Is currently receiving services through Part C Early Intervention (EI).
* Able to participate in natural caregiver-child routines and play activities.
* At least one primary caregiver is available and willing to participate in weekly coach... | 697 | 1e7a044e96fb000760100e2f5273a7530fc1dd036cc21b8aaf33f1c119aa75ed | success |
57 | NCT07748780 | inclusion_criteria | 3 | NCT07748780_3 | eligibility_constraint_question | What is the requirement for caregiver involvement in this clinical trial? | * Under 36 months of age at enrollment.
* Has a clinical diagnosis of autism.
* Is currently receiving services through Part C Early Intervention (EI).
* Able to participate in natural caregiver-child routines and play activities.
* At least one primary caregiver is available and willing to participate in weekly coach... | 697 | 1e7a044e96fb000760100e2f5273a7530fc1dd036cc21b8aaf33f1c119aa75ed | success |
58 | NCT07711730 | title | 1 | NCT07711730_1 | trial_topic_question | What is the focus of this clinical trial? | Telecare-Mediated Psychosocial and Cognitive Intervention for Children and Adolescents With Limb-Girdle Muscular Dystrophy | 122 | c3f73f53b129a6d5c89003b63dcec14466ee7d0b673978689307b5d112245b91 | success |
59 | NCT07711730 | summary | 2 | NCT07711730_2 | clinical_population_question | Who are the participants in this study? | This clinical trial aims to evaluate the efficacy of a telecare-mediated psychosocial and cognitive intervention for children and adolescents aged 7 to 17 with limb-girdle muscular dystrophy. This group-based intervention (comprising 5 participants) consists of 12 weekly one-hour sessions. The objective of the interven... | 580 | 85602c7339cdce3a86ebd29bb9b46438857162d2fb3cc0861dec2a8890711ad4 | success |
60 | NCT07711730 | inclusion_criteria | 3 | NCT07711730_3 | patient_profile_question | What is the specific muscle disorder being studied in this clinical trial? | * To be diagnosed with limb-girdle muscular dystrophy
* Being between 7 and 17 years old
* Having signed an informed consent form through their legal guardians prior to participation in the study
* Having Spanish as one of their main languages
* Having access to a computer (with a camera, microphone and speakers integr... | 388 | 83688a3f8f8ddbcad92291be849d65c20ded6f782fd18bd2c4ce64f52cebb225 | success |
61 | NCT07711730 | inclusion_criteria | 3 | NCT07711730_3 | eligibility_constraint_question | What is the age range for participants in this study? | * To be diagnosed with limb-girdle muscular dystrophy
* Being between 7 and 17 years old
* Having signed an informed consent form through their legal guardians prior to participation in the study
* Having Spanish as one of their main languages
* Having access to a computer (with a camera, microphone and speakers integr... | 388 | 83688a3f8f8ddbcad92291be849d65c20ded6f782fd18bd2c4ce64f52cebb225 | success |
62 | NCT07724158 | title | 1 | NCT07724158_1 | trial_topic_question | What is the focus of this clinical trial? | Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity | 115 | 96dbc8d9fcd54f9170f1c1240c76a189bd063209b2a4400d957a4ca78e29bbd0 | success |
63 | NCT07724158 | summary | 2 | NCT07724158_2 | study_objective_question | What interventions are being tested to improve bladder and bowel symptoms in adolescents with obesity? | Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel. These symptoms can negatively affect quality of life, emotional well-being, school participation, and social re... | 2,499 | 6f2a88a3168db0fe2edc809ff4246a9a5379cdded1d8d4333fb09955a171b788 | success |
64 | NCT07724158 | summary | 2 | NCT07724158_2 | clinical_population_question | Which adolescents with obesity will be included in this study? | Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel. These symptoms can negatively affect quality of life, emotional well-being, school participation, and social re... | 2,499 | 6f2a88a3168db0fe2edc809ff4246a9a5379cdded1d8d4333fb09955a171b788 | success |
65 | NCT07724158 | inclusion_criteria | 3 | NCT07724158_3 | patient_profile_question | What is the age range for adolescents in this clinical trial? | * Male or female adolescents aged 13 to 18 years.
* Obesity defined as BMI z-score ≥2, according to the WHO growth reference for school-aged children and adolescents.
* Currently receiving obesity treatment at the Pediatric Outpatient Clinic, Department of Pediatrics, Hospital de Santa Maria, Unidade Local de Saúde de ... | 542 | 57a0c1f0d7126a14bea030fcae1e2d92caf77ef0ac3e21114e80687e6942e265 | success |
66 | NCT07724158 | inclusion_criteria | 3 | NCT07724158_3 | eligibility_constraint_question | What is the BMI z-score threshold for obesity eligibility in this study? | * Male or female adolescents aged 13 to 18 years.
* Obesity defined as BMI z-score ≥2, according to the WHO growth reference for school-aged children and adolescents.
* Currently receiving obesity treatment at the Pediatric Outpatient Clinic, Department of Pediatrics, Hospital de Santa Maria, Unidade Local de Saúde de ... | 542 | 57a0c1f0d7126a14bea030fcae1e2d92caf77ef0ac3e21114e80687e6942e265 | success |
67 | NCT07674212 | title | 1 | NCT07674212_1 | trial_topic_question | What is the focus of the Take5Care+ clinical trial? | Take5Care+: A Self-management Educational Intervention Take5Care+: A Self-management Educational Intervention to Support the Haematology Patients' Journey Following a Neoplastic Diagnosis. | 188 | 58251a2c11481cd1b9290223566f5ba382b8a3cb8decdf9e66194ab456cd35b1 | success |
68 | NCT07674212 | summary | 2 | NCT07674212_2 | study_objective_question | What is being studied in this clinical trial? | Patients who are diagnosed with haematological malignancies may feel that they have little or no control over their health which can be distressing. However, a diagnosis can also be the opportunity for a "teachable moment" during which patients are more likely to open to behaviour change, which can positively impact on... | 1,923 | 2f5782eb419cc91dbca24bd26f1cb16f212421f778e8a7395847391d64062bd4 | success |
69 | NCT07674212 | summary | 2 | NCT07674212_2 | clinical_population_question | Who are the participants in this study? | Patients who are diagnosed with haematological malignancies may feel that they have little or no control over their health which can be distressing. However, a diagnosis can also be the opportunity for a "teachable moment" during which patients are more likely to open to behaviour change, which can positively impact on... | 1,923 | 2f5782eb419cc91dbca24bd26f1cb16f212421f778e8a7395847391d64062bd4 | success |
70 | NCT07674212 | inclusion_criteria | 3 | NCT07674212_3 | patient_profile_question | What conditions are patients diagnosed with within the last 3 months? | * 18 years or older.
* Have been diagnosed within the last 3 months with one of the eligible conditions listed in Table 1.
* Be managed with either:
* Active monitoring, or
* Non-intensive oral therapy, defined as outpatient oral regimens that do not require inpatient initiation and have lower expected toxicity (e.g... | 550 | b18fd8257766de6e511754a7887f5656ad40e1cf920c7055dbb6cc1d5d4deda3 | success |
71 | NCT07674212 | inclusion_criteria | 3 | NCT07674212_3 | eligibility_constraint_question | What is the minimum ECOG Performance Status required for trial eligibility? | * 18 years or older.
* Have been diagnosed within the last 3 months with one of the eligible conditions listed in Table 1.
* Be managed with either:
* Active monitoring, or
* Non-intensive oral therapy, defined as outpatient oral regimens that do not require inpatient initiation and have lower expected toxicity (e.g... | 550 | b18fd8257766de6e511754a7887f5656ad40e1cf920c7055dbb6cc1d5d4deda3 | success |
72 | NCT07751185 | title | 1 | NCT07751185_1 | trial_topic_question | What is the focus of the SHINE clinical trial? | Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE) Support and Healing Intervention for Navigating Parental Cancer Experiences (SHINE): A Mixed-Methods Study to Develop and Pilot-Test a Family-Centered Psychosocial Intervention for Adolescents With a Parent Diagnosed With Cance... | 321 | 8a5a207f622cc5dc97c5c6e8bb10f59224975e322ae4cee7ee4b05772debd832 | success |
73 | NCT07751185 | summary | 2 | NCT07751185_2 | study_objective_question | What family-centered program is being developed to support adolescents whose parent has been diagnosed with cancer? | e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed with cancer.
The study has two phases. In the first phase, parents and adolescents will parti... | 1,189 | 8324aa1901b568196dda774c53c2817d71180d036ce05a3cb508534ec89de733 | success |
74 | NCT07751185 | summary | 2 | NCT07751185_2 | clinical_population_question | Who are the participants in this study, and what is their specific experience or situation? | e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed with cancer.
The study has two phases. In the first phase, parents and adolescents will parti... | 1,189 | 8324aa1901b568196dda774c53c2817d71180d036ce05a3cb508534ec89de733 | success |
75 | NCT07751185 | inclusion_criteria | 3 | NCT07751185_3 | patient_profile_question | What is the cancer stage for the participating adolescents? | Parent or caregiver aged 18 years or older with a documented diagnosis of Stage I-IV (or equivalent) cancer.
Parent or caregiver has at least one adolescent child between the ages of 10 and 17 years living in the household.
Parent/caregiver and adolescent are able to communicate in English or Spanish. Parent or careg... | 552 | d4983022fd5997407ff965851213c9d2edc82a7945b630eef92e0cfad5547c53 | success |
76 | NCT07751185 | inclusion_criteria | 3 | NCT07751185_3 | eligibility_constraint_question | What is the age range of the adolescent children involved in this clinical trial? | Parent or caregiver aged 18 years or older with a documented diagnosis of Stage I-IV (or equivalent) cancer.
Parent or caregiver has at least one adolescent child between the ages of 10 and 17 years living in the household.
Parent/caregiver and adolescent are able to communicate in English or Spanish. Parent or careg... | 552 | d4983022fd5997407ff965851213c9d2edc82a7945b630eef92e0cfad5547c53 | success |
77 | NCT07717320 | title | 1 | NCT07717320_1 | trial_topic_question | What is the focus of this clinical trial in Panama? | Suicidal Risk in Adults in Panama: Validation of a Clinical Intervention Protocol | 81 | 6c73d32b0d01f2601a4d2f91347612e9ca7ff5d7e9ef0e5b8bd69889794754e5 | success |
78 | NCT07717320 | summary | 2 | NCT07717320_2 | study_objective_question | What is being studied or evaluated in this clinical trial? | This study aims to validate MBT as an effective and viable intervention for implementation in public health services, with the potential to directly impact suicide prevention policies in the region. | 198 | 5fb06f8bf59ebc451fbae9eda662a4121adabe3e18b06a769a69a0dd76fdd341 | success |
79 | NCT07717320 | summary | 2 | NCT07717320_2 | clinical_population_question | Who or what population is the focus of this suicide prevention study? | This study aims to validate MBT as an effective and viable intervention for implementation in public health services, with the potential to directly impact suicide prevention policies in the region. | 198 | 5fb06f8bf59ebc451fbae9eda662a4121adabe3e18b06a769a69a0dd76fdd341 | success |
80 | NCT07717320 | inclusion_criteria | 3 | NCT07717320_3 | patient_profile_question | What is the patient's mental health status being evaluated for? | * Age and consent
* Presence of suicidal ideation or active behavior in the last month, assessed using the C-SSRS (e.g., intentional ideation, plan, or preparatory behavior)
* Depressive or anxious symptoms (Score ≥ 10 on the PHQ-9, indicating at least moderate depressive symptoms, or Score ≥ 10 on the GAD-7, suggestin... | 461 | 551aef08e472c0daedb426e2572a566880ee1c9cf95c2d9459765408bf05fbc6 | success |
81 | NCT07717320 | inclusion_criteria | 3 | NCT07717320_3 | eligibility_constraint_question | At what age range are patients eligible to participate in this clinical trial? | * Age and consent
* Presence of suicidal ideation or active behavior in the last month, assessed using the C-SSRS (e.g., intentional ideation, plan, or preparatory behavior)
* Depressive or anxious symptoms (Score ≥ 10 on the PHQ-9, indicating at least moderate depressive symptoms, or Score ≥ 10 on the GAD-7, suggestin... | 461 | 551aef08e472c0daedb426e2572a566880ee1c9cf95c2d9459765408bf05fbc6 | success |
82 | NCT07710001 | title | 1 | NCT07710001_1 | trial_topic_question | What is the focus of this clinical trial? | Study on Influencing Factors and Intervention of Silent Aspiration After Heart Valve Operation in Elderly Patients | 114 | 0fb3a1c47625ba7b1cd9a5fa2265ccf48e4fb4d6b5ea52b3f8c6a27cecf7dc74 | success |
83 | NCT07710001 | summary | 2 | NCT07710001_2 | clinical_population_question | Who are the patients being studied in this trial? | Objective To investigate the safety and effectiveness of interference electrical stimulation in the prevention of silent aspiration after heart valve surgery in elderly patients. Silent aspiration was diagnosed when either pepsin level \>200 ng/ml or α-amylase level \>1685 U/L was detected in airway secretions. | 312 | e1f371404256cffca36a721197f596e5c3b712df2618f0f725afe28e17a3a796 | success |
84 | NCT07710001 | inclusion_criteria | 3 | NCT07710001_3 | patient_profile_question | What is the patient's cardiac function classification? | * Simple valve surgery
* Age ≥60 years old
* NYHA cardiac function Grade II-III
* ASA Grade II-III
* No dysphagia screened by SSA before surgery
| 146 | 2853bc0dd85ccab7617fad7fb2c803b53f14dff43b1ed196ac3f2664f91e1d21 | success |
85 | NCT07710001 | inclusion_criteria | 3 | NCT07710001_3 | eligibility_constraint_question | Is the patient at least 60 years old? | * Simple valve surgery
* Age ≥60 years old
* NYHA cardiac function Grade II-III
* ASA Grade II-III
* No dysphagia screened by SSA before surgery
| 146 | 2853bc0dd85ccab7617fad7fb2c803b53f14dff43b1ed196ac3f2664f91e1d21 | success |
86 | NCT07689799 | title | 1 | NCT07689799_1 | trial_topic_question | What is the focus of this clinical trial in Saudi Arabia? | Structured Leadership Intervention for Nurses in Saudi Arabia. Effects of a Structured Leadership Intervention on Nursing Work Environment, Job Satisfaction, and Turnover Intentions: A Randomized Controlled Trial. | 213 | e3292ca0a0807a44a2e7e37192566326330a175907d9a4210c3ec42480629c2d | success |
87 | NCT07689799 | summary | 2 | NCT07689799_2 | study_objective_question | What is being studied in this clinical trial? | This study is a randomized controlled trial designed to evaluate the effectiveness of a structured transformational leadership educational program on nurses' work environment, job satisfaction, and turnover intentions in acute care hospitals in Saudi Arabia. | 258 | 5ac0e027a1d0cfe8d64f158346a4d398650e81e41fac093f703b34d315a791e2 | success |
88 | NCT07689799 | summary | 2 | NCT07689799_2 | clinical_population_question | Who are the participants in this study, specifically regarding their work environment and location? | This study is a randomized controlled trial designed to evaluate the effectiveness of a structured transformational leadership educational program on nurses' work environment, job satisfaction, and turnover intentions in acute care hospitals in Saudi Arabia. | 258 | 5ac0e027a1d0cfe8d64f158346a4d398650e81e41fac093f703b34d315a791e2 | success |
89 | NCT07689799 | inclusion_criteria | 3 | NCT07689799_3 | patient_profile_question | What is the typical professional background of participants in this trial? | * Registered nurses with 6 or more months of clinical experience.
* Full-time employment in inpatient units.
| 110 | 37f57daa99b263cf5ac9a17a17b9be52411eff9df5ea6f12ab956d1ef25887bb | success |
90 | NCT07689799 | inclusion_criteria | 3 | NCT07689799_3 | eligibility_constraint_question | Is full-time employment in inpatient units a requirement for participation in this clinical trial? | * Registered nurses with 6 or more months of clinical experience.
* Full-time employment in inpatient units.
| 110 | 37f57daa99b263cf5ac9a17a17b9be52411eff9df5ea6f12ab956d1ef25887bb | success |
91 | NCT07737912 | title | 1 | NCT07737912_1 | trial_topic_question | What is the focus of the SpinePal Open Pilot clinical trial? | SpinePal Open Pilot User-Centered Development of an App-Based Cognitive-Behavioral Intervention to Reduce Persistent Opioid Use and Opioid Related Problems Following Spine Surgery | 179 | d98fd74ce37fa08f5290fa00a02a7ca6a8863ee86b567edf9b9bf664921a227c | success |
92 | NCT07737912 | summary | 2 | NCT07737912_2 | study_objective_question | What is being studied in this clinical trial regarding patients undergoing spine surgery? | SpinePal is a self-guided digital intervention developed for patients undergoing spine surgery. The goal of this study is to learn if SpinePal is acceptable to people undergoing spine surgery. The main questions the investigators aim to answer are:
* Is the SpinePal platform considered usable and acceptable by people ... | 709 | 740dea15e7a26c92d4949564e6a7a23753a72512b4f2dcbaf887dfd5e38f4bda | success |
93 | NCT07737912 | inclusion_criteria | 3 | NCT07737912_3 | patient_profile_question | Who is eligible for this clinical trial? | * 18 years or older
* English-speaking
* Able and willing to provide informed consent
* Scheduled for lumbar or cervical fusion surgery at least 2 weeks from the date of enrollment
* Owns a smartphone with reliable internet and/or data access
* Willing to engage with SpinePal and physiological monitoring via wrist-worn... | 329 | 3bc5e5827d9aba100b525bc964cf7f0640ca29a41332c7aae004a27705491bf2 | success |
94 | NCT07737912 | inclusion_criteria | 3 | NCT07737912_3 | eligibility_constraint_question | What are the smartphone requirements for participants in this study? | * 18 years or older
* English-speaking
* Able and willing to provide informed consent
* Scheduled for lumbar or cervical fusion surgery at least 2 weeks from the date of enrollment
* Owns a smartphone with reliable internet and/or data access
* Willing to engage with SpinePal and physiological monitoring via wrist-worn... | 329 | 3bc5e5827d9aba100b525bc964cf7f0640ca29a41332c7aae004a27705491bf2 | success |
95 | NCT07720947 | title | 1 | NCT07720947_1 | trial_topic_question | What is the focus of this clinical trial? | Smartphone-based Nature Noticing Intervention Smartphone-based Nature Noticing Intervention for Cultivating Social Connectedness | 128 | 45f00be33640bec5400d4b6069af9463a60edab13c6f5f15850f0a40ba66f013 | success |
96 | NCT07720947 | summary | 2 | NCT07720947_2 | clinical_population_question | Who is the target population for this nature-noticing intervention? | We used a mixed-methods approach involving a RCT study followed by focus group discussions to obtain a more integrative understanding of the effects of a 10-week nature-noticing intervention. | 191 | 21b9e65d813350bfa620296b80b8e707f724ae9d8af8fa688e26eb25565ad696 | success |
97 | NCT07720947 | inclusion_criteria | 3 | NCT07720947_3 | patient_profile_question | What is the age range of the participants in this clinical trial? | * Hong Kong secondary school students
* 15-17 years
| 53 | ee4be68676cb2ea77fc7c67eb1b4afb39b6aa9789328748dc4cae8671050f006 | success |
98 | NCT07720947 | inclusion_criteria | 3 | NCT07720947_3 | eligibility_constraint_question | Are Hong Kong secondary school students eligible to participate in this study? | * Hong Kong secondary school students
* 15-17 years
| 53 | ee4be68676cb2ea77fc7c67eb1b4afb39b6aa9789328748dc4cae8671050f006 | success |
99 | NCT07654205 | title | 1 | NCT07654205_1 | trial_topic_question | What is the focus of this clinical trial? | Smartphone-based Intervention for Young Adults With ADHD Training Inhibitory Control Using Personalized Strategies (TIPS): A Randomized Controlled Feasibility Trial of a Smartphone-Based Intervention for Alcohol Use in Young Adults With ADHD | 241 | 963a61943b5836f9ef60d4d9eee82c6c164d7ce9307baba7aa8ab7e827942aa1 | success |
Dataset details:-
- This is the iteration 2 of the previous dataset on same repository.
- Overall similar usecase:-(i)embedding model fine-tune/training for CT(clinical trials) domain, thereby aiding downstream tsak like ranked retrieval document generation comparing 2 or more anchors, anchor vs chunks via cosine similarity.
Key changes(from earlier version):-
Greater granulation of chunks so to have:- (i) cleaner directed retreival from fine tuned embedding model; (ii) better up model metrics particularly NDCG, MRR and precision of embedded model.
More refinement in segregation of inclusion-exclusion picking possible corner cases (in terms of written format of CTs) from CT's eligiblity module.
Decrease chunk length(with proper otlier analysis), so model fine-tune/train happens efficiently(greater batch size yeilding more genralized model, less time taken).
Each CT(unique nctId) here has 3 chunks with respective number of anchors(questions) from each:-
- Title--->1 anchor ('trial_topic_question')
- Summary----> 2 anchors ('study_objective_question', 'clinical_population_question')
- Inclusion_criteria----> 2 anchors ('patient_profile_question', 'eligibility_constraint_question')
Extra care in system prompt of LLM(used to generate synthetic anchors) so to avoid generic or stock formulations that could apply equally well to many clinical trials, thereby generating other possible natural anchors to a chunk that are more focused to the given trial(corresponding nctId), its relevant disease, intervention, population, clinical context, or eligibility information.
For chunks appearing across CT records(different nctId), a hash out of chunks(hexadecimal with utf -8 encoding) named "unique_chunk_identifier" is taken as *actual_id of chunks(not
document_id)*. optimum content-level retrieval from any anchors. For CT mapoing afterwards, we are also preserving document_id. Also priortizing (content-level retrieval> clinical trial
record retreival) helps:-
- Wider application :- anchor-to-anchor, anchor-to-chunk, chunk-to-chunk simlarity analysis.
- Better precision, NDCG, MRR metrics etc in inference (opposite to when document_id would have been used as it would have penalized the anchor-positive(indices mapping) if anchor showed correlation with same chunk in different CT(ncTid).
- The fact that unique_chunk_identifiers & document_id coexist shall aid a local anchor ai (specific to a CT nctId) of same chunk ci (present in different nctIds) to align with all instances of the chunk CI = [ ci1 , ci2 ,... ciN ]
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