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NCT07661732
title
1
NCT07661732_1
trial_topic_question
What is the focus of the ELITE-HFpEF study?
eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF Randomized Trial Of A Digital Lifestyle Education Strategy In Patients With Heart Failure And Overweight Or Obesity: The ELITE-HFpEF Study
198
d08b7d5b9810dc265979e5d3031190f66ac14fc9a8e315e23f3d6a578ac0d2d0
success
1
NCT07661732
summary
2
NCT07661732_2
study_objective_question
Is there evidence that a digital lifestyle education program improves exercise capacity in adults with heart failure with preserved ejection fraction?
The goal of this clinical trial is to learn if a digital lifestyle education program improves exercise capacity in adults who have heart failure with preserved ejection fraction (HFpEF) and overweight or obesity. HFpEF is a type of heart failure in which the heart muscle is stiff and does not relax well, even though it...
1,202
e4e312b512120909e8d2af05c7e4ca6624ee2f2787c82161cb7468e44e9b5a2b
success
2
NCT07661732
summary
2
NCT07661732_2
clinical_population_question
Are overweight or obese adults with heart failure with preserved ejection fraction being recruited for this clinical trial?
The goal of this clinical trial is to learn if a digital lifestyle education program improves exercise capacity in adults who have heart failure with preserved ejection fraction (HFpEF) and overweight or obesity. HFpEF is a type of heart failure in which the heart muscle is stiff and does not relax well, even though it...
1,202
e4e312b512120909e8d2af05c7e4ca6624ee2f2787c82161cb7468e44e9b5a2b
success
3
NCT07661732
inclusion_criteria
3
NCT07661732_3
patient_profile_question
What are the symptoms consistent with heart failure in this trial?
* Age over 18 years * Body mass index (BMI) over 27 kg/m² * Symptoms consistent with heart failure * Left ventricular ejection fraction (LVEF) of 50% or higher * Elevated NT-proBNP according to the European Society of Cardiology age-adjusted rule-in thresholds: 125 pg/mL or higher if under 50 years, 250 pg/mL or higher...
501
3ca3b2b2bd1be031044984f628e17bb566c6f527061a324fe5bbf389d58e4652
success
4
NCT07661732
inclusion_criteria
3
NCT07661732_3
eligibility_constraint_question
What is the minimum BMI required for inclusion in this clinical trial?
* Age over 18 years * Body mass index (BMI) over 27 kg/m² * Symptoms consistent with heart failure * Left ventricular ejection fraction (LVEF) of 50% or higher * Elevated NT-proBNP according to the European Society of Cardiology age-adjusted rule-in thresholds: 125 pg/mL or higher if under 50 years, 250 pg/mL or higher...
501
3ca3b2b2bd1be031044984f628e17bb566c6f527061a324fe5bbf389d58e4652
success
5
NCT07704034
title
1
NCT07704034_1
trial_topic_question
What is the focus of this clinical trial?
Wearable-Triggered Digital Safety Net for Real-Time Monitoring and Intervention in Leptomeningeal Metastasis
108
8f1e1bde5e487d1aadc4af2ba31319921d9ea0932dc8619afc67b66922aab95a
success
6
NCT07704034
inclusion_criteria
3
NCT07704034_3
patient_profile_question
What is the specific type of metastasis that participants must have?
* Participants must have leptomeningeal metastasis (LMM) diagnosed per clinical, imaging, and/or CSF/cytology criteria (cytology, flow cytometry, or circulating tumor DNA), arising from any solid or hematologic tumor primary. * Participants must be undergoing active anti-cancer therapy (systemic, intrathecal, and/or ra...
1,159
9e18c8a554c89d6cdb998499fb73940fd8097c918b4a703124c00344db7a9635
success
7
NCT07704034
inclusion_criteria
3
NCT07704034_3
eligibility_constraint_question
What is the minimum age requirement for study enrollment?
* Participants must have leptomeningeal metastasis (LMM) diagnosed per clinical, imaging, and/or CSF/cytology criteria (cytology, flow cytometry, or circulating tumor DNA), arising from any solid or hematologic tumor primary. * Participants must be undergoing active anti-cancer therapy (systemic, intrathecal, and/or ra...
1,159
9e18c8a554c89d6cdb998499fb73940fd8097c918b4a703124c00344db7a9635
success
8
NCT07704034
summary
2
NCT07704034_2
study_objective_question
Is this clinical trial investigating the use of consumer Smartwatches for monitoring health in patients with leptomeningeal metastasis?
This research study is for participants diagnosed with leptomeningeal metastasis disease (LMM), a condition where cancer has spread to the fluid and membranes surround the brain and spinal cord. The purpose of this study is to find out whether a consumer Smartwatch can continuously monitor the participant's health and ...
515
7fd34c5543eff871725a7df99e11051bed92afc42ffcc2154bfbf1ed981c011f
success
9
NCT07704034
summary
2
NCT07704034_2
clinical_population_question
Who are the participants being recruited for this clinical trial, specifically those diagnosed with leptomeningeal metastasis disease?
This research study is for participants diagnosed with leptomeningeal metastasis disease (LMM), a condition where cancer has spread to the fluid and membranes surround the brain and spinal cord. The purpose of this study is to find out whether a consumer Smartwatch can continuously monitor the participant's health and ...
515
7fd34c5543eff871725a7df99e11051bed92afc42ffcc2154bfbf1ed981c011f
success
10
NCT07698509
title
1
NCT07698509_1
trial_topic_question
What is the focus of this clinical trial?
Virtual Lifestyle Medicine Group Visits for High Blood Pressure A Scalable, Lifestyle Medicine Intervention for Hypertension Using Virtual Group Shared Medical Appointments
172
b078c8474731ff7351485144fdcc3882e1e7674db8d7bdebb8552399a7dcd906
success
11
NCT07698509
summary
2
NCT07698509_2
clinical_population_question
Who is the target population for this virtual Lifestyle medicine shared medical appointments study?
The purpose of this study is to learn whether virtual Lifestyle medicine shared medical appointments (LMSMAs) can help people better manage their blood pressure and improve their overall health.
194
9afa9188885bd538c7595651e2dd44187bb3be6f67f1ca03012dac4d47eee2f3
success
12
NCT07698509
inclusion_criteria
3
NCT07698509_3
patient_profile_question
What is the current diagnosis of hypertension for this clinical trial?
* Current diagnosis of hypertension (ICD codes I10.0-I14.0 billed within the last 5 years Essential HTN, Essential HTN, Primary HTN) * Currently receives care at a UTPhysicians; Last seen by a PCP at Victory location within the last 1 year. * Able to participate in a virtual format * Willingness to participate and enga...
358
1988ae491d7ef0fb63644d62eafae16c7f5c7e26e45ea89ff15ad96ff5cbf6fb
success
13
NCT07698509
inclusion_criteria
3
NCT07698509_3
eligibility_constraint_question
Must participants have received care at a UTPhysicians within the last year?
* Current diagnosis of hypertension (ICD codes I10.0-I14.0 billed within the last 5 years Essential HTN, Essential HTN, Primary HTN) * Currently receives care at a UTPhysicians; Last seen by a PCP at Victory location within the last 1 year. * Able to participate in a virtual format * Willingness to participate and enga...
358
1988ae491d7ef0fb63644d62eafae16c7f5c7e26e45ea89ff15ad96ff5cbf6fb
success
14
NCT07637097
title
1
NCT07637097_1
trial_topic_question
What is the focus of this clinical trial?
VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body Dementia Reducing Depression in Family Caregivers of Persons Living With Lewy Body Dementia Through Tailored Asynchronous Online Intervention.
214
d18761eeebddef6b9c9509752dbaffc1b22286a9d81371f56905c7901e4d328d
success
15
NCT07637097
summary
2
NCT07637097_2
clinical_population_question
Who are the family caregivers being targeted in this study?
This study tests whether a tailored, fully asynchronous online group intervention (VOCALE LBD) reduces depression in family caregivers of people with Lewy Body Dementia (LBD), compared to standard educational materials. LBD is the second most common form of degenerative dementia and causes distinct challenges, includin...
1,337
408ec8e976f14317b8149094539dbd38168549c7dcfecf442c81baf9081e208d
success
16
NCT07637097
inclusion_criteria
3
NCT07637097_3
patient_profile_question
Who has a confirmed diagnosis of Lewy Body Dementia (LBD) or LBD mixed pathology?
* Current family member or informal (unpaid) caregiver of a person with a confirmed diagnosis of Lewy Body Dementia (LBD) or LBD mixed pathology * Experiences depressive symptoms as defined by a score of 5 or higher on the Patient Health Questionnaire-9 (PHQ-9) * Able to read, write, and speak English * Has access to a...
488
874051ac9a49833db9775129a47f11e8a362ce9354085a982dc10e19c289509f
success
17
NCT07637097
inclusion_criteria
3
NCT07637097_3
eligibility_constraint_question
What is the minimum score on the Patient Health Questionnaire-9 (PHQ-9) for a caregiver to be eligible?
* Current family member or informal (unpaid) caregiver of a person with a confirmed diagnosis of Lewy Body Dementia (LBD) or LBD mixed pathology * Experiences depressive symptoms as defined by a score of 5 or higher on the Patient Health Questionnaire-9 (PHQ-9) * Able to read, write, and speak English * Has access to a...
488
874051ac9a49833db9775129a47f11e8a362ce9354085a982dc10e19c289509f
success
18
NCT07717671
title
1
NCT07717671_1
trial_topic_question
What is the focus of the VIPPSTAR-G1 clinical trial?
VIPPSTAR-G1 Digital Early Intervention for Visual Impairment VIPPSTAR-G1: A Multicenter Randomized Controlled Trial Evaluating a Caregiver-mediated Digital Intervention to Promote Visual Function and Neurodevelopment in Infants at Risk of/With Visual Impairment
261
49899359709950ab8c0253ea496f26f43ee86d26509011951cda54255b2c9e7e
success
19
NCT07717671
summary
2
NCT07717671_2
clinical_population_question
Who are the participants at risk of or with visual impairment being targeted in the VIPPSTAR-G1 study?
Visual impairment in infancy is associated with significant risks for neurodevelopmental impairment. Early intervention based on enriched visual and multisensory experiences may promote neuroplasticity and improve developmental outcomes, but implementation of intensive interventions in routine clinical practice remains...
1,260
59babb5c86e3d671d1d8748cb542ca4cbfbdab5242f204ef5ceed7e611997bd4
success
20
NCT07717671
inclusion_criteria
3
NCT07717671_3
patient_profile_question
What is the typical gestational age of patients in this trial?
* Gestational age ≤32 weeks OR full-term/newborns\>32 weeks of age with neonatal distress (Apgar ≤5 at 10 minutes) * NAVEG score ≥3 * At least one neurological or neuroimaging abnormality: * 3 abnormal signs at ATNAT neurological examination OR Abnormal cranial ultrasound findings OR Abnormal MRI findings * Age ≤42 ...
382
822de48868e5737606b84d1796af999d8ee20eaf7f0eb486ba8a8e9f44d80ef6
success
21
NCT07717671
inclusion_criteria
3
NCT07717671_3
eligibility_constraint_question
Are patients with a NAVEG score less than 3 eligible for this trial?
* Gestational age ≤32 weeks OR full-term/newborns\>32 weeks of age with neonatal distress (Apgar ≤5 at 10 minutes) * NAVEG score ≥3 * At least one neurological or neuroimaging abnormality: * 3 abnormal signs at ATNAT neurological examination OR Abnormal cranial ultrasound findings OR Abnormal MRI findings * Age ≤42 ...
382
822de48868e5737606b84d1796af999d8ee20eaf7f0eb486ba8a8e9f44d80ef6
success
22
NCT07738224
title
1
NCT07738224_1
trial_topic_question
What is the focus of this clinical trial?
Using the Babble Boot Camp© Speech Therapy Approach With Babies Born Prematurely Babble Boot Camp© for Preterm Infants: A Trial of a Proactive Speech/Language Intervention
171
c11fe7e765449beec8fffafa57eda8fff86c941d61956771d251d8322405a192
success
23
NCT07738224
summary
2
NCT07738224_2
study_objective_question
What speech therapy intervention is being evaluated for its effectiveness in supporting early communication in preterm infants?
Babble Boot Camp focuses on early speech and language development, environmental enrichment and supporting parent-infant interaction with the aim of improving communication outcomes and parental well-being in at risk children. The goal of this clinical trial is to learn if this parent-coaching speech therapy intervent...
1,182
1f57bbebc491ba6120a1a0d3212533569e957298e8c4952ff05446f74d397fff
success
24
NCT07738224
inclusion_criteria
3
NCT07738224_3
patient_profile_question
What is the gestational age criterion for infant participants?
* Infants born \<32 weeks' gestational age (GA) * Infants medically stable and not ventilator dependent at recruitment * Primary language spoken at home is English * Participants able to attend 6 months of telehealth early intervention * Infants less than 5.5 months corrected age
282
ef6346341a5b480c3a3d53071dfcfd257a5c32a6e04f1d748cdc310c74d1e068
success
25
NCT07738224
inclusion_criteria
3
NCT07738224_3
eligibility_constraint_question
Is English proficiency a requirement for telehealth early intervention?
* Infants born \<32 weeks' gestational age (GA) * Infants medically stable and not ventilator dependent at recruitment * Primary language spoken at home is English * Participants able to attend 6 months of telehealth early intervention * Infants less than 5.5 months corrected age
282
ef6346341a5b480c3a3d53071dfcfd257a5c32a6e04f1d748cdc310c74d1e068
success
26
NCT07751458
title
1
NCT07751458_1
trial_topic_question
What is the focus of the WISE Study?
The WISE Study (WhatsApp Intervention for Sleep in the Elderly) The WISE Study (WhatsApp Intervention for Sleep in the Elderly): Targeting Insomnia and Loneliness With a Digital Booklet
185
60b97f6685327928cd101f898fc3c6cfb4495052fb1103bc90658a25eab01b6a
success
27
NCT07751458
summary
2
NCT07751458_2
study_objective_question
What is being studied in this clinical trial?
Sleep hygiene education is an educational effort to teach healthy sleep habits and behaviors to improve sleep quality, duration, and regularity naturally without the use of medication; however, this approach has not been established in Indonesia. This study aims to establish a sleep hygiene education care model among l...
1,514
50760d5f34206056a70babcb8528f211e05707e524e2c28178609cf8d00c50ed
success
28
NCT07751458
summary
2
NCT07751458_2
clinical_population_question
Who are the participants targeted by this study?
Sleep hygiene education is an educational effort to teach healthy sleep habits and behaviors to improve sleep quality, duration, and regularity naturally without the use of medication; however, this approach has not been established in Indonesia. This study aims to establish a sleep hygiene education care model among l...
1,514
50760d5f34206056a70babcb8528f211e05707e524e2c28178609cf8d00c50ed
success
29
NCT07751458
inclusion_criteria
3
NCT07751458_3
patient_profile_question
What is the primary clinical phenotype of interest in this trial?
* Elderly individuals diagnosed with loneliness * Reported experiencing sleep disturbances in the past 2 weeks, either continuously or intermittently * Experiencing insomnia with a total score of ≥ 8 on the Indonesian version of the Insomnia Severity Index (ISI) during screening * Able to communicate in Indonesian
317
469f1a88cb084bd0c08d9c050f62214918c05760602fcf0cc3e1408f894587df
success
30
NCT07751458
inclusion_criteria
3
NCT07751458_3
eligibility_constraint_question
What is the minimum score on the Indonesian version of the Insomnia Severity Index required for eligibility?
* Elderly individuals diagnosed with loneliness * Reported experiencing sleep disturbances in the past 2 weeks, either continuously or intermittently * Experiencing insomnia with a total score of ≥ 8 on the Indonesian version of the Insomnia Severity Index (ISI) during screening * Able to communicate in Indonesian
317
469f1a88cb084bd0c08d9c050f62214918c05760602fcf0cc3e1408f894587df
success
31
NCT07711301
title
1
NCT07711301_1
trial_topic_question
What is the focus of The Science Tooth Fairy clinical trial?
The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting Tooth Book Evaluation
171
e8c689a3180f95a9d8f92ddf0c4a7b4a3b56f3a83ff5739a12ae7dd23d9137ca
success
32
NCT07711301
summary
2
NCT07711301_2
study_objective_question
What is being studied in this clinical trial?
Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development. While donating baby teeth to scientific research is painless and simple, researchers often face challenges collecting them. Past studies show that donatio...
3,101
38e46cee7b8a1a8fd9c936dba53baff1286f4733b84e46d191753969138835c5
success
33
NCT07711301
summary
2
NCT07711301_2
clinical_population_question
Who are the participants in this study, and what is their age range?
Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development. While donating baby teeth to scientific research is painless and simple, researchers often face challenges collecting them. Past studies show that donatio...
3,101
38e46cee7b8a1a8fd9c936dba53baff1286f4733b84e46d191753969138835c5
success
34
NCT07711301
inclusion_criteria
3
NCT07711301_3
patient_profile_question
What is the age range for the children participating in this clinical trial?
* Biological or non-biological parents (e.g., legal caregivers or guardians) of children aged 4-10 years
106
c3b5edd88ecfd24732e33997abb182d0a4e69f68de8fa42cc56fa1a1e8310feb
success
35
NCT07711301
inclusion_criteria
3
NCT07711301_3
eligibility_constraint_question
Are biological parents eligible to participate in this clinical trial?
* Biological or non-biological parents (e.g., legal caregivers or guardians) of children aged 4-10 years
106
c3b5edd88ecfd24732e33997abb182d0a4e69f68de8fa42cc56fa1a1e8310feb
success
36
NCT07690605
title
1
NCT07690605_1
trial_topic_question
What is the focus of this clinical trial?
The Genomic and Well-Being Impacts of an Extraverted Behavior Intervention
74
e66af89c57a4d56659d8425266d78c11919acf056931a9779df21ae74bfaac53
success
37
NCT07690605
summary
2
NCT07690605_2
clinical_population_question
Who are the participants in this study, and what is their focus?
8-week randomized intervention (with 3-month follow-up) that examines the impact of increased sociable behavior on emotional well-being and immune health profile
161
141e9b5c6b7b0d2607af85e83bafce5fcbfaf1129c4aa6f5053e8c3085490532
success
38
NCT07690605
inclusion_criteria
3
NCT07690605_3
patient_profile_question
What is the minimum age requirement for trial participants?
* Age 18 or older
19
87e817eca50c9e90a2923918b9d0c49897f17b62248a289e1ae164e3c84c9dd4
success
39
NCT07690605
inclusion_criteria
3
NCT07690605_3
eligibility_constraint_question
Is there an upper age limit for patients to be eligible for this clinical trial?
* Age 18 or older
19
87e817eca50c9e90a2923918b9d0c49897f17b62248a289e1ae164e3c84c9dd4
success
40
NCT07755631
title
1
NCT07755631_1
trial_topic_question
What is the focus of the BASIC-S Feasibility Study?
The BASIC-S Feasibility Study for Vascular Risk Reduction Piloting an Integrated Lifestyle Intervention for Vascular Risk Reduction: The BASIC-S Feasibility Study
162
f3b1971b88906d275d18b295471c8b794730e22ab6e7f47eb6a2812f07ef747b
success
41
NCT07755631
summary
2
NCT07755631_2
study_objective_question
What lifestyle changes is this study evaluating for reducing vascular risk factors?
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging. To address this, we developed the BASIC-S framework, targeting Blood pressure, Activity, Sleep, Interaction (socially), Consumption (nutrition), and Support using partner...
1,051
7a5a191f72b8118e1f068238f389fc5cb9196b19cc156a7610af55deed0c7332
success
42
NCT07755631
summary
2
NCT07755631_2
clinical_population_question
Who are the participants in this cluster-randomized pilot trial?
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging. To address this, we developed the BASIC-S framework, targeting Blood pressure, Activity, Sleep, Interaction (socially), Consumption (nutrition), and Support using partner...
1,051
7a5a191f72b8118e1f068238f389fc5cb9196b19cc156a7610af55deed0c7332
success
43
NCT07755631
inclusion_criteria
3
NCT07755631_3
patient_profile_question
Are participants in this clinical trial healthcare workers?
* Adults aged 18 years and older currently employed at or recently retired from the London Health Sciences Centre (LHSC) or Western University (with an operational focus on pre-retirees aged 50 years and older). * Spouse or cohabitating partner of an enrolled primary participant (partner enrollment is optional but stro...
566
e9a1a31395ef6c1d04f4916ffd90733fb3baf6e1d74c5ae30c117af1f460f79e
success
44
NCT07755631
inclusion_criteria
3
NCT07755631_3
eligibility_constraint_question
Is age a requirement for enrolling in this study?
* Adults aged 18 years and older currently employed at or recently retired from the London Health Sciences Centre (LHSC) or Western University (with an operational focus on pre-retirees aged 50 years and older). * Spouse or cohabitating partner of an enrolled primary participant (partner enrollment is optional but stro...
566
e9a1a31395ef6c1d04f4916ffd90733fb3baf6e1d74c5ae30c117af1f460f79e
success
45
NCT07666139
title
1
NCT07666139_1
trial_topic_question
What is the focus of the CARES Study?
The 'Comprehensive Adherence Resource and Empowerment Support' (CARES) Study Adapting the 'Comprehensive Adherence Resource and Empowerment Support' Intervention for Multiple PrEP Methods Among Adolescent Girls and Young Women in South Africa and Zimbabwe
255
2342f29e6ca64a2257a72a433c1fcced26980c1276138c0f714a07bd0f939085
success
46
NCT07666139
summary
2
NCT07666139_2
study_objective_question
What is being studied in this clinical trial?
The primary aim of this study is to adapt the Comprehensive Adherence Resource and Empowerment Support (CARES) intervention to support adolescent girls and young women (AGYW) aged 16-24 in Zimbabwe and South Africa in effectively using various forms of pre-exposure prophylaxis (PrEP), specifically oral, ring, and injec...
1,154
6af49faab00ad5f1f5cf6fceef5c1672e1a5af0eeb4e4388928789badfc044d0
success
47
NCT07666139
summary
2
NCT07666139_2
clinical_population_question
Who is the target population for this study?
The primary aim of this study is to adapt the Comprehensive Adherence Resource and Empowerment Support (CARES) intervention to support adolescent girls and young women (AGYW) aged 16-24 in Zimbabwe and South Africa in effectively using various forms of pre-exposure prophylaxis (PrEP), specifically oral, ring, and injec...
1,154
6af49faab00ad5f1f5cf6fceef5c1672e1a5af0eeb4e4388928789badfc044d0
success
48
NCT07666139
inclusion_criteria
3
NCT07666139_3
patient_profile_question
What age group is targeted in this clinical trial?
Aim 2: Inclusion (AGYW): * age 16-24 years (in Zimbabwe, participants aged 16 to 17 years must meet the legal criteria for emancipation to be eligible) * has initiated PrEP during the study, or no more than 6 months before the study initiation date (for LEN PrEP), or no more than 3 months before the study initiation ...
658
76fd53b8b53fdc586ae18352352b4d7d3dcbad72b1814c42514ae0f79bb11f9a
success
49
NCT07666139
inclusion_criteria
3
NCT07666139_3
eligibility_constraint_question
What are the requirements for participants who have initiated PrEP before the study initiation date?
Aim 2: Inclusion (AGYW): * age 16-24 years (in Zimbabwe, participants aged 16 to 17 years must meet the legal criteria for emancipation to be eligible) * has initiated PrEP during the study, or no more than 6 months before the study initiation date (for LEN PrEP), or no more than 3 months before the study initiation ...
658
76fd53b8b53fdc586ae18352352b4d7d3dcbad72b1814c42514ae0f79bb11f9a
success
50
NCT07695818
title
1
NCT07695818_1
trial_topic_question
What is the focus of this clinical trial?
Testing and Evaluation of the Returning to the Land Intervention to Address and Prevent Substance Misuse
104
36aa3b9d245abc3dd06a177b7be1ac5fb0052e6f63f0430addd9d9ad765d03c4
success
51
NCT07695818
summary
2
NCT07695818_2
clinical_population_question
Who is the target population for this study?
This study aims to test the Returning to the Land intervention in partnership with a tribal community. The program is designed to address caregiver substance use and child emotional and behavioral development.
209
42bdb8d8391054410fbf5750b31bf5d840690161d2b432bb628cdda550b96433
success
52
NCT07695818
inclusion_criteria
3
NCT07695818_3
patient_profile_question
What is the age range of eligible participants in this clinical trial?
* Reside on or near the Rocky Boy Reservation (\~50-mile round trip); * Aged 14-19 years; * Parent or primary caregiver to at least one child who will be age 1-5 years at the start of the intervention.
203
40efe526612cd1d8e8804bf7cf77145d777f764833841416e2c39da74ef91252
success
53
NCT07695818
inclusion_criteria
3
NCT07695818_3
eligibility_constraint_question
Do participants need to reside on or near the Rocky Boy Reservation to be eligible for this study?
* Reside on or near the Rocky Boy Reservation (\~50-mile round trip); * Aged 14-19 years; * Parent or primary caregiver to at least one child who will be age 1-5 years at the start of the intervention.
203
40efe526612cd1d8e8804bf7cf77145d777f764833841416e2c39da74ef91252
success
54
NCT07748780
title
1
NCT07748780_1
trial_topic_question
What is the focus of this clinical trial?
Testing a Blended Social-Communication and Social-Emotional Intervention for Autistic Toddlers
94
aa5150c1908e3e2ff8c75920b41e72ac58ffc764e5ccaf008ae86dea4f781e14
success
55
NCT07748780
summary
2
NCT07748780_2
clinical_population_question
What population of autistic toddlers is targeted by this study?
Autistic toddlers often need support to develop both social-communication and social-emotional skills. Social communication (such as making requests or sharing attention) is usually addressed in early intervention, but social-emotional needs (such as expressing feelings or learning to cope with frustration) are often o...
1,448
dbfdfe652f0857db27b3c8fe0e504b0951dccca0df349e06a018c38252ea14ea
success
56
NCT07748780
inclusion_criteria
3
NCT07748780_3
patient_profile_question
What is the age criterion for participants?
* Under 36 months of age at enrollment. * Has a clinical diagnosis of autism. * Is currently receiving services through Part C Early Intervention (EI). * Able to participate in natural caregiver-child routines and play activities. * At least one primary caregiver is available and willing to participate in weekly coach...
697
1e7a044e96fb000760100e2f5273a7530fc1dd036cc21b8aaf33f1c119aa75ed
success
57
NCT07748780
inclusion_criteria
3
NCT07748780_3
eligibility_constraint_question
What is the requirement for caregiver involvement in this clinical trial?
* Under 36 months of age at enrollment. * Has a clinical diagnosis of autism. * Is currently receiving services through Part C Early Intervention (EI). * Able to participate in natural caregiver-child routines and play activities. * At least one primary caregiver is available and willing to participate in weekly coach...
697
1e7a044e96fb000760100e2f5273a7530fc1dd036cc21b8aaf33f1c119aa75ed
success
58
NCT07711730
title
1
NCT07711730_1
trial_topic_question
What is the focus of this clinical trial?
Telecare-Mediated Psychosocial and Cognitive Intervention for Children and Adolescents With Limb-Girdle Muscular Dystrophy
122
c3f73f53b129a6d5c89003b63dcec14466ee7d0b673978689307b5d112245b91
success
59
NCT07711730
summary
2
NCT07711730_2
clinical_population_question
Who are the participants in this study?
This clinical trial aims to evaluate the efficacy of a telecare-mediated psychosocial and cognitive intervention for children and adolescents aged 7 to 17 with limb-girdle muscular dystrophy. This group-based intervention (comprising 5 participants) consists of 12 weekly one-hour sessions. The objective of the interven...
580
85602c7339cdce3a86ebd29bb9b46438857162d2fb3cc0861dec2a8890711ad4
success
60
NCT07711730
inclusion_criteria
3
NCT07711730_3
patient_profile_question
What is the specific muscle disorder being studied in this clinical trial?
* To be diagnosed with limb-girdle muscular dystrophy * Being between 7 and 17 years old * Having signed an informed consent form through their legal guardians prior to participation in the study * Having Spanish as one of their main languages * Having access to a computer (with a camera, microphone and speakers integr...
388
83688a3f8f8ddbcad92291be849d65c20ded6f782fd18bd2c4ce64f52cebb225
success
61
NCT07711730
inclusion_criteria
3
NCT07711730_3
eligibility_constraint_question
What is the age range for participants in this study?
* To be diagnosed with limb-girdle muscular dystrophy * Being between 7 and 17 years old * Having signed an informed consent form through their legal guardians prior to participation in the study * Having Spanish as one of their main languages * Having access to a computer (with a camera, microphone and speakers integr...
388
83688a3f8f8ddbcad92291be849d65c20ded6f782fd18bd2c4ce64f52cebb225
success
62
NCT07724158
title
1
NCT07724158_1
trial_topic_question
What is the focus of this clinical trial?
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
115
96dbc8d9fcd54f9170f1c1240c76a189bd063209b2a4400d957a4ca78e29bbd0
success
63
NCT07724158
summary
2
NCT07724158_2
study_objective_question
What interventions are being tested to improve bladder and bowel symptoms in adolescents with obesity?
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel. These symptoms can negatively affect quality of life, emotional well-being, school participation, and social re...
2,499
6f2a88a3168db0fe2edc809ff4246a9a5379cdded1d8d4333fb09955a171b788
success
64
NCT07724158
summary
2
NCT07724158_2
clinical_population_question
Which adolescents with obesity will be included in this study?
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel. These symptoms can negatively affect quality of life, emotional well-being, school participation, and social re...
2,499
6f2a88a3168db0fe2edc809ff4246a9a5379cdded1d8d4333fb09955a171b788
success
65
NCT07724158
inclusion_criteria
3
NCT07724158_3
patient_profile_question
What is the age range for adolescents in this clinical trial?
* Male or female adolescents aged 13 to 18 years. * Obesity defined as BMI z-score ≥2, according to the WHO growth reference for school-aged children and adolescents. * Currently receiving obesity treatment at the Pediatric Outpatient Clinic, Department of Pediatrics, Hospital de Santa Maria, Unidade Local de Saúde de ...
542
57a0c1f0d7126a14bea030fcae1e2d92caf77ef0ac3e21114e80687e6942e265
success
66
NCT07724158
inclusion_criteria
3
NCT07724158_3
eligibility_constraint_question
What is the BMI z-score threshold for obesity eligibility in this study?
* Male or female adolescents aged 13 to 18 years. * Obesity defined as BMI z-score ≥2, according to the WHO growth reference for school-aged children and adolescents. * Currently receiving obesity treatment at the Pediatric Outpatient Clinic, Department of Pediatrics, Hospital de Santa Maria, Unidade Local de Saúde de ...
542
57a0c1f0d7126a14bea030fcae1e2d92caf77ef0ac3e21114e80687e6942e265
success
67
NCT07674212
title
1
NCT07674212_1
trial_topic_question
What is the focus of the Take5Care+ clinical trial?
Take5Care+: A Self-management Educational Intervention Take5Care+: A Self-management Educational Intervention to Support the Haematology Patients' Journey Following a Neoplastic Diagnosis.
188
58251a2c11481cd1b9290223566f5ba382b8a3cb8decdf9e66194ab456cd35b1
success
68
NCT07674212
summary
2
NCT07674212_2
study_objective_question
What is being studied in this clinical trial?
Patients who are diagnosed with haematological malignancies may feel that they have little or no control over their health which can be distressing. However, a diagnosis can also be the opportunity for a "teachable moment" during which patients are more likely to open to behaviour change, which can positively impact on...
1,923
2f5782eb419cc91dbca24bd26f1cb16f212421f778e8a7395847391d64062bd4
success
69
NCT07674212
summary
2
NCT07674212_2
clinical_population_question
Who are the participants in this study?
Patients who are diagnosed with haematological malignancies may feel that they have little or no control over their health which can be distressing. However, a diagnosis can also be the opportunity for a "teachable moment" during which patients are more likely to open to behaviour change, which can positively impact on...
1,923
2f5782eb419cc91dbca24bd26f1cb16f212421f778e8a7395847391d64062bd4
success
70
NCT07674212
inclusion_criteria
3
NCT07674212_3
patient_profile_question
What conditions are patients diagnosed with within the last 3 months?
* 18 years or older. * Have been diagnosed within the last 3 months with one of the eligible conditions listed in Table 1. * Be managed with either: * Active monitoring, or * Non-intensive oral therapy, defined as outpatient oral regimens that do not require inpatient initiation and have lower expected toxicity (e.g...
550
b18fd8257766de6e511754a7887f5656ad40e1cf920c7055dbb6cc1d5d4deda3
success
71
NCT07674212
inclusion_criteria
3
NCT07674212_3
eligibility_constraint_question
What is the minimum ECOG Performance Status required for trial eligibility?
* 18 years or older. * Have been diagnosed within the last 3 months with one of the eligible conditions listed in Table 1. * Be managed with either: * Active monitoring, or * Non-intensive oral therapy, defined as outpatient oral regimens that do not require inpatient initiation and have lower expected toxicity (e.g...
550
b18fd8257766de6e511754a7887f5656ad40e1cf920c7055dbb6cc1d5d4deda3
success
72
NCT07751185
title
1
NCT07751185_1
trial_topic_question
What is the focus of the SHINE clinical trial?
Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE) Support and Healing Intervention for Navigating Parental Cancer Experiences (SHINE): A Mixed-Methods Study to Develop and Pilot-Test a Family-Centered Psychosocial Intervention for Adolescents With a Parent Diagnosed With Cance...
321
8a5a207f622cc5dc97c5c6e8bb10f59224975e322ae4cee7ee4b05772debd832
success
73
NCT07751185
summary
2
NCT07751185_2
study_objective_question
What family-centered program is being developed to support adolescents whose parent has been diagnosed with cancer?
e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed with cancer. The study has two phases. In the first phase, parents and adolescents will parti...
1,189
8324aa1901b568196dda774c53c2817d71180d036ce05a3cb508534ec89de733
success
74
NCT07751185
summary
2
NCT07751185_2
clinical_population_question
Who are the participants in this study, and what is their specific experience or situation?
e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed with cancer. The study has two phases. In the first phase, parents and adolescents will parti...
1,189
8324aa1901b568196dda774c53c2817d71180d036ce05a3cb508534ec89de733
success
75
NCT07751185
inclusion_criteria
3
NCT07751185_3
patient_profile_question
What is the cancer stage for the participating adolescents?
Parent or caregiver aged 18 years or older with a documented diagnosis of Stage I-IV (or equivalent) cancer. Parent or caregiver has at least one adolescent child between the ages of 10 and 17 years living in the household. Parent/caregiver and adolescent are able to communicate in English or Spanish. Parent or careg...
552
d4983022fd5997407ff965851213c9d2edc82a7945b630eef92e0cfad5547c53
success
76
NCT07751185
inclusion_criteria
3
NCT07751185_3
eligibility_constraint_question
What is the age range of the adolescent children involved in this clinical trial?
Parent or caregiver aged 18 years or older with a documented diagnosis of Stage I-IV (or equivalent) cancer. Parent or caregiver has at least one adolescent child between the ages of 10 and 17 years living in the household. Parent/caregiver and adolescent are able to communicate in English or Spanish. Parent or careg...
552
d4983022fd5997407ff965851213c9d2edc82a7945b630eef92e0cfad5547c53
success
77
NCT07717320
title
1
NCT07717320_1
trial_topic_question
What is the focus of this clinical trial in Panama?
Suicidal Risk in Adults in Panama: Validation of a Clinical Intervention Protocol
81
6c73d32b0d01f2601a4d2f91347612e9ca7ff5d7e9ef0e5b8bd69889794754e5
success
78
NCT07717320
summary
2
NCT07717320_2
study_objective_question
What is being studied or evaluated in this clinical trial?
This study aims to validate MBT as an effective and viable intervention for implementation in public health services, with the potential to directly impact suicide prevention policies in the region.
198
5fb06f8bf59ebc451fbae9eda662a4121adabe3e18b06a769a69a0dd76fdd341
success
79
NCT07717320
summary
2
NCT07717320_2
clinical_population_question
Who or what population is the focus of this suicide prevention study?
This study aims to validate MBT as an effective and viable intervention for implementation in public health services, with the potential to directly impact suicide prevention policies in the region.
198
5fb06f8bf59ebc451fbae9eda662a4121adabe3e18b06a769a69a0dd76fdd341
success
80
NCT07717320
inclusion_criteria
3
NCT07717320_3
patient_profile_question
What is the patient's mental health status being evaluated for?
* Age and consent * Presence of suicidal ideation or active behavior in the last month, assessed using the C-SSRS (e.g., intentional ideation, plan, or preparatory behavior) * Depressive or anxious symptoms (Score ≥ 10 on the PHQ-9, indicating at least moderate depressive symptoms, or Score ≥ 10 on the GAD-7, suggestin...
461
551aef08e472c0daedb426e2572a566880ee1c9cf95c2d9459765408bf05fbc6
success
81
NCT07717320
inclusion_criteria
3
NCT07717320_3
eligibility_constraint_question
At what age range are patients eligible to participate in this clinical trial?
* Age and consent * Presence of suicidal ideation or active behavior in the last month, assessed using the C-SSRS (e.g., intentional ideation, plan, or preparatory behavior) * Depressive or anxious symptoms (Score ≥ 10 on the PHQ-9, indicating at least moderate depressive symptoms, or Score ≥ 10 on the GAD-7, suggestin...
461
551aef08e472c0daedb426e2572a566880ee1c9cf95c2d9459765408bf05fbc6
success
82
NCT07710001
title
1
NCT07710001_1
trial_topic_question
What is the focus of this clinical trial?
Study on Influencing Factors and Intervention of Silent Aspiration After Heart Valve Operation in Elderly Patients
114
0fb3a1c47625ba7b1cd9a5fa2265ccf48e4fb4d6b5ea52b3f8c6a27cecf7dc74
success
83
NCT07710001
summary
2
NCT07710001_2
clinical_population_question
Who are the patients being studied in this trial?
Objective To investigate the safety and effectiveness of interference electrical stimulation in the prevention of silent aspiration after heart valve surgery in elderly patients. Silent aspiration was diagnosed when either pepsin level \>200 ng/ml or α-amylase level \>1685 U/L was detected in airway secretions.
312
e1f371404256cffca36a721197f596e5c3b712df2618f0f725afe28e17a3a796
success
84
NCT07710001
inclusion_criteria
3
NCT07710001_3
patient_profile_question
What is the patient's cardiac function classification?
* Simple valve surgery * Age ≥60 years old * NYHA cardiac function Grade II-III * ASA Grade II-III * No dysphagia screened by SSA before surgery
146
2853bc0dd85ccab7617fad7fb2c803b53f14dff43b1ed196ac3f2664f91e1d21
success
85
NCT07710001
inclusion_criteria
3
NCT07710001_3
eligibility_constraint_question
Is the patient at least 60 years old?
* Simple valve surgery * Age ≥60 years old * NYHA cardiac function Grade II-III * ASA Grade II-III * No dysphagia screened by SSA before surgery
146
2853bc0dd85ccab7617fad7fb2c803b53f14dff43b1ed196ac3f2664f91e1d21
success
86
NCT07689799
title
1
NCT07689799_1
trial_topic_question
What is the focus of this clinical trial in Saudi Arabia?
Structured Leadership Intervention for Nurses in Saudi Arabia. Effects of a Structured Leadership Intervention on Nursing Work Environment, Job Satisfaction, and Turnover Intentions: A Randomized Controlled Trial.
213
e3292ca0a0807a44a2e7e37192566326330a175907d9a4210c3ec42480629c2d
success
87
NCT07689799
summary
2
NCT07689799_2
study_objective_question
What is being studied in this clinical trial?
This study is a randomized controlled trial designed to evaluate the effectiveness of a structured transformational leadership educational program on nurses' work environment, job satisfaction, and turnover intentions in acute care hospitals in Saudi Arabia.
258
5ac0e027a1d0cfe8d64f158346a4d398650e81e41fac093f703b34d315a791e2
success
88
NCT07689799
summary
2
NCT07689799_2
clinical_population_question
Who are the participants in this study, specifically regarding their work environment and location?
This study is a randomized controlled trial designed to evaluate the effectiveness of a structured transformational leadership educational program on nurses' work environment, job satisfaction, and turnover intentions in acute care hospitals in Saudi Arabia.
258
5ac0e027a1d0cfe8d64f158346a4d398650e81e41fac093f703b34d315a791e2
success
89
NCT07689799
inclusion_criteria
3
NCT07689799_3
patient_profile_question
What is the typical professional background of participants in this trial?
* Registered nurses with 6 or more months of clinical experience. * Full-time employment in inpatient units.
110
37f57daa99b263cf5ac9a17a17b9be52411eff9df5ea6f12ab956d1ef25887bb
success
90
NCT07689799
inclusion_criteria
3
NCT07689799_3
eligibility_constraint_question
Is full-time employment in inpatient units a requirement for participation in this clinical trial?
* Registered nurses with 6 or more months of clinical experience. * Full-time employment in inpatient units.
110
37f57daa99b263cf5ac9a17a17b9be52411eff9df5ea6f12ab956d1ef25887bb
success
91
NCT07737912
title
1
NCT07737912_1
trial_topic_question
What is the focus of the SpinePal Open Pilot clinical trial?
SpinePal Open Pilot User-Centered Development of an App-Based Cognitive-Behavioral Intervention to Reduce Persistent Opioid Use and Opioid Related Problems Following Spine Surgery
179
d98fd74ce37fa08f5290fa00a02a7ca6a8863ee86b567edf9b9bf664921a227c
success
92
NCT07737912
summary
2
NCT07737912_2
study_objective_question
What is being studied in this clinical trial regarding patients undergoing spine surgery?
SpinePal is a self-guided digital intervention developed for patients undergoing spine surgery. The goal of this study is to learn if SpinePal is acceptable to people undergoing spine surgery. The main questions the investigators aim to answer are: * Is the SpinePal platform considered usable and acceptable by people ...
709
740dea15e7a26c92d4949564e6a7a23753a72512b4f2dcbaf887dfd5e38f4bda
success
93
NCT07737912
inclusion_criteria
3
NCT07737912_3
patient_profile_question
Who is eligible for this clinical trial?
* 18 years or older * English-speaking * Able and willing to provide informed consent * Scheduled for lumbar or cervical fusion surgery at least 2 weeks from the date of enrollment * Owns a smartphone with reliable internet and/or data access * Willing to engage with SpinePal and physiological monitoring via wrist-worn...
329
3bc5e5827d9aba100b525bc964cf7f0640ca29a41332c7aae004a27705491bf2
success
94
NCT07737912
inclusion_criteria
3
NCT07737912_3
eligibility_constraint_question
What are the smartphone requirements for participants in this study?
* 18 years or older * English-speaking * Able and willing to provide informed consent * Scheduled for lumbar or cervical fusion surgery at least 2 weeks from the date of enrollment * Owns a smartphone with reliable internet and/or data access * Willing to engage with SpinePal and physiological monitoring via wrist-worn...
329
3bc5e5827d9aba100b525bc964cf7f0640ca29a41332c7aae004a27705491bf2
success
95
NCT07720947
title
1
NCT07720947_1
trial_topic_question
What is the focus of this clinical trial?
Smartphone-based Nature Noticing Intervention Smartphone-based Nature Noticing Intervention for Cultivating Social Connectedness
128
45f00be33640bec5400d4b6069af9463a60edab13c6f5f15850f0a40ba66f013
success
96
NCT07720947
summary
2
NCT07720947_2
clinical_population_question
Who is the target population for this nature-noticing intervention?
We used a mixed-methods approach involving a RCT study followed by focus group discussions to obtain a more integrative understanding of the effects of a 10-week nature-noticing intervention.
191
21b9e65d813350bfa620296b80b8e707f724ae9d8af8fa688e26eb25565ad696
success
97
NCT07720947
inclusion_criteria
3
NCT07720947_3
patient_profile_question
What is the age range of the participants in this clinical trial?
* Hong Kong secondary school students * 15-17 years
53
ee4be68676cb2ea77fc7c67eb1b4afb39b6aa9789328748dc4cae8671050f006
success
98
NCT07720947
inclusion_criteria
3
NCT07720947_3
eligibility_constraint_question
Are Hong Kong secondary school students eligible to participate in this study?
* Hong Kong secondary school students * 15-17 years
53
ee4be68676cb2ea77fc7c67eb1b4afb39b6aa9789328748dc4cae8671050f006
success
99
NCT07654205
title
1
NCT07654205_1
trial_topic_question
What is the focus of this clinical trial?
Smartphone-based Intervention for Young Adults With ADHD Training Inhibitory Control Using Personalized Strategies (TIPS): A Randomized Controlled Feasibility Trial of a Smartphone-Based Intervention for Alcohol Use in Young Adults With ADHD
241
963a61943b5836f9ef60d4d9eee82c6c164d7ce9307baba7aa8ab7e827942aa1
success
End of preview. Expand in Data Studio

Dataset details:-

  • This is the iteration 2 of the previous dataset on same repository.
  • Overall similar usecase:-(i)embedding model fine-tune/training for CT(clinical trials) domain, thereby aiding downstream tsak like ranked retrieval document generation comparing 2 or more anchors, anchor vs chunks via cosine similarity.

Key changes(from earlier version):-

  • Greater granulation of chunks so to have:- (i) cleaner directed retreival from fine tuned embedding model; (ii) better up model metrics particularly NDCG, MRR and precision of embedded model.

  • More refinement in segregation of inclusion-exclusion picking possible corner cases (in terms of written format of CTs) from CT's eligiblity module.

  • Decrease chunk length(with proper otlier analysis), so model fine-tune/train happens efficiently(greater batch size yeilding more genralized model, less time taken).

  • Each CT(unique nctId) here has 3 chunks with respective number of anchors(questions) from each:-

    • Title--->1 anchor ('trial_topic_question')
    • Summary----> 2 anchors ('study_objective_question', 'clinical_population_question')
    • Inclusion_criteria----> 2 anchors ('patient_profile_question', 'eligibility_constraint_question')
  • Extra care in system prompt of LLM(used to generate synthetic anchors) so to avoid generic or stock formulations that could apply equally well to many clinical trials, thereby generating other possible natural anchors to a chunk that are more focused to the given trial(corresponding nctId), its relevant disease, intervention, population, clinical context, or eligibility information.

  • For chunks appearing across CT records(different nctId), a hash out of chunks(hexadecimal with utf -8 encoding) named "unique_chunk_identifier" is taken as *actual_id of chunks(not

  • document_id)*. optimum content-level retrieval from any anchors. For CT mapoing afterwards, we are also preserving document_id. Also priortizing (content-level retrieval> clinical trial

  • record retreival) helps:-

    • Wider application :- anchor-to-anchor, anchor-to-chunk, chunk-to-chunk simlarity analysis.
    • Better precision, NDCG, MRR metrics etc in inference (opposite to when document_id would have been used as it would have penalized the anchor-positive(indices mapping) if anchor showed correlation with same chunk in different CT(ncTid).
    • The fact that unique_chunk_identifiers & document_id coexist shall aid a local anchor ai (specific to a CT nctId) of same chunk ci (present in different nctIds) to align with all instances of the chunk CI = [ ci1 , ci2 ,... ciN ]
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