model_input stringlengths 704 790k | clean_target stringlengths 37 3.68k |
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background: background despite significant progress in drug treatment , the prognosis of patients with advanced pulmonary arterial hypertension ( pah ) remains extremely poor . many pre clinical studies have reported the efficacy of stem cell ( sc ) therapy for pah ; however , this approach remains controversial . the ... | conclusions sc therapy is effective for pah in pre clinical studies . these results may help to st and ardise pre clinical animal studies and provide a theoretical basis for clinical trial design in the future . |
background: background pulmonary arterial hypertension is a devastating disease , which leads to right heart failure and premature death . recent evidence suggests that endothelin receptor antagonists may be promising drugs in the treatment of pulmonary arterial hypertension . objectives to evaluate the efficacy of end... | there was a trend for endothelin receptor antagonists to reduce mortality ( or 0.48 ; 95 % ci 0.21 to 1.09 ) , and limited data suggest that endothelin receptor antagonists improve borg dyspnoea score and cardiopulmonary haemodynamics in symptomatic patients . hepatic toxicity was not common , and endothelin receptor a... |
background: background to achieve sufficient myocardial perfusion in st-segment elevation myocardial infa rct ion ( stemi ) patients receiving primary percutaneous coronary intervention ( ppci ) , many adjunctive therapies have been proposed . previous trials have reported variances in myocardial perfusion improvement ... | this present meta- analysis suggests that statin pretreatment might be effective in improving myocardial perfusion in stemi patients |
background: waterpipe tobacco smoking is growing in popularity despite adverse health effects among users . we systematic ally review ed the literature , search ing medline , embase and web of science , for interventions targeting prevention and cessation of waterpipe tobacco smoking .
evidence:
title: effect of cessa... | in conclusion , there is a lack of evidence of effectiveness for most waterpipe interventions . |
background: context impaired sexual function has a significant effect on quality of life . various patient-reported outcome measures ( proms ) are available to evaluate sexual function . the quality of the proms to be used for neurologic patients remains unknown . objective to systematic ally review which vali date d p... | several proms have been identified to evaluate sexual function in neurologic patients . strong evidence was found only for the multiple sclerosis intimacy and sexuality question naire-15 and multiple sclerosis intimacy and sexuality question naire-19 for patients with ms , although evidence was lacking for certain meas... |
background: introduction surgical stress in the presence of fasting worsens the catabolic state , causes insulin resistance and may delay recovery . carbohydrate rich drinks given preoperatively may ameliorate these deleterious effects . a systematic review was undertaken to analyse the effect of preoperative carbohydr... | preoperative carbohydrate drinks significantly improved insulin resistance and indices of patient comfort following surgery , especially hunger , thirst , malaise , anxiety and nausea . no definite conclusions could be made regarding preservation of muscle mass . following ingestion of carbohydrate drinks , no adverse ... |
background: background and purpose — the safety and efficacy of restarting anticoagulation therapy after intracranial hemorrhage ( ich ) remain unclear . we performed a systematic review and meta- analysis to summarize the associations of anticoagulation resumption with the subsequent risk of ich recurrence and thrombo... | conclusions — in observational studies , reinstitution of anticoagulation after ich was associated with a lower risk of thromboembolic complications and a similar risk of ich recurrence . |
"background: objective to determine the risk of neuropsychiatric adverse events associated with use (...TRUNCATED) | "this meta- analysis found no evidence of an increased risk of suicide or attempted suicide , suicid(...TRUNCATED) |
"background: objective the purpose of this systematic review was to compare the survival and complic(...TRUNCATED) | "overall , the 5-year complication rates were low . the most frequent complications were secondary c(...TRUNCATED) |
"background: background and purpose knowledge about robust and unbiased factors that predict outcome(...TRUNCATED) | "because of insufficient method ological quality of most prognostic studies , the predictive value o(...TRUNCATED) |
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