Patent ID: 8551130

Claim:
A high-speed rotational atherectomy system for delivering at least one therapeutic agent to a biological lumen wall during a high-speed rotation atherectomy procedure within the biological lumen, comprising: a guide wire having a maximum diameter less than the diameter of the biological lumen; a flexible elongated, rotatable drive shaft advanceable over the guide wire, the drive shaft having a rotational axis; an eccentric abrading head comprising an external surface and attached to the drive shaft, the eccentric abrading head comprising a center of mass that is offset from the rotational axis of the drive shaft; a therapeutic agent reservoir; a fluid supply line in fluid communication with the therapeutic agent reservoir; a pump in operative connection with the therapeutic agent reservoir; a controller in operative communication with the pump and the therapeutic agent reservoir; a non-rotating therapeutic agent delivery sheath, the sheath comprising a lumen therethrough, the drive shaft slidably and rotatably disposed in the sheath lumen, the non-rotating therapeutic agent delivery sheath further comprising an inflatable balloon arranged on a distal end thereof, the lumen of the therapeutic agent delivery sheath in fluid communication with the therapeutic agent reservoir and the inflatable balloon, and the inflatable balloon comprising a plurality of pores in direct fluid communication with the lumen of the therapeutic agent delivery sheath; a catheter disposed over the sheath; and means for drivingly urging the at least one therapeutic agent radially outwardly away from the eccentric abrading head and into the lumen wall.