Patent ID: 8293253

Claim:
An injection composition comprising (i) a salt formed between (a) an amino acid ester of formula I: wherein R is the amino acid side chain; and R 1 is a C 1 to C 22 hydrocarbon group or amino acid amide of formula (II): wherein R is the amino acid side chain; R 3 is a C 1 to C 22 hydrocarbon group; and R 4 is hydrogen or a C 1 to C 22 hydrocarbon group, and (b) an acidic pharmaceutically active compound; and (ii) a pharmaceutically acceptable organic solvent; formulated to be administered to an animal by injection, wherein the composition is substantially free of water, the composition is injectable and forms a precipitate when injected into water, and the composition, when administered to an animal by injection, forms a depot that releases the pharmaceutically active compound over time.