Patent ID: 8163532

Claim:
An isolated microorganism of the genus Corynebacterium: wherein said microorganism is obtained by genetic modification from a starting microorganism such that said microorganism has an increased amount or activity of a cob(I)alamin-dependent methionine synthase I (MetH) reactivation system compared to said starting microorganism, wherein said cob(I)alamin dependent MetH reactivation system comprises at least: (a) one electron transport protein selected from the group comprising fdxC having SEQ ID NO:2 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:2, fdxD having SEQ ID NO:4 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:4, fdxA having SEQ ID NO:6 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:6; and (b) one electron transfer protein-reductase selected from the group comprising fprA1 having SEQ ID NO:12 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:12, fprA2 having SEQ ID NO:14 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:14, fprA3 having SEQ ID NO:16 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:16, fldR1 having SEQ ID NO:18 and functional homologues thereof providing the same enzymatic activity and having at least 95% sequence identity to SEQ ID NO:18; and wherein the amount, activity, or both, of at least said electron transfer protein or of at least said electron transfer protein-reductase is increased compared to said starting microorganism.