Patent ID: 7678772

Claim:
A method for treating ROS mediated diseases and conditions comprising administering to a host in need thereof an effective amount of a composition comprised of a plant extract, wherein said plant extract is comprised of a 7-hydroxychrome or a mixture of 7-hydroxychromones wherein said 7-hydroxychrome(s) are selected from the group of compounds having the following structure: wherein R 1 , R 2 and R 3 are independently selected from the group consisting of —H, —OH, SH, alkyl, alkenyl, oxoalkyl, oxoalkenyl, hydroxylalkyl, hydroxylalkenyl, —OR, SR, NH 2 , —NRH, —NR 2 , —NR 3 + X − , an ester selected from the group consisting of gallate, acetate, cinnamoyl and hydroxyl-cinnamoyl esters, trihydroxybenzoyl esters and caffeoyl esters and a glycoside, a thioglycoside, a nitrogen glycoside, or a carbon glycoside, wherein said glycoside is linked to the 7-hydroxychromone by a carbon or oxygen of a single or a combination of multiple sugars selected from the group consisting of aldopentoses, methyl aldopentose, aldohexoses and ketohexoses and wherein said glycoside is optionally substituted to form an ester selected from the group consisting of gallate, acetate, cinnamoyl and hydroxyl-cinnamoyl esters, trihydroxybenzoyl esters and caffeoyl esters; wherein said alkyl and/or alkenyl group is a straight and/or branched chain having between 1-20 carbon atoms with and/or without double bonds in different positions; X is selected from the group of pharmaceutically acceptable counter anions consisting of hydroxyl, chloride, iodide, sulfate, phosphate, acetate, fluoride, and carbonate; R is an alkyl group having between 1-20 carbon atoms and a pharmaceutically acceptable carrier; and wherein the composition is comprised of 1% to 100 of the 7-hydroxychromone.