Patent ID: 8754066

Claim:
A compound having Formula I, its enantiomers, diastereoisomers, hydrates, solvates and tautomers or a pharmaceutically acceptable salt thereof, wherein: A is C 6-10 aryl, heterocycle, C 3-8 cycloalkyl or C 3-8 cycloalkenyl; B is C 6-10 aryl, heterocycle, C 3-8 cycloalkyl or C 3-8 cycloalkenyl; R 1 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , NR 14 R 15 or hydroxyl; R 2 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , NR 14 R 15 or hydroxyl; R 3 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , NR 14 R 15 or hydroxyl; R 4 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , NR 14 R 15 or hydroxyl; R 5 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , NR 14 R 15 or hydroxyl; R 6 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , NR 14 R 15 or hydroxyl; R 7 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , C 6-10 aryl, heterocycle, C 3-8 cycloakyl, C 3-8 cycloalkenyl, NR 14 R 15 or hydroxyl; R 8 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , C 6-10 aryl, heterocycle, C 3-8 cycloakyl, C 3-8 cycloalkenyl, NR 14 R 15 or hydroxyl; R 9 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , C 6-10 aryl, heterocycle, C 3-8 cycloakyl, C 3-8 cycloalkenyl, NR 14 R 15 or hydroxyl; R 10 is H, halogen, —OC 1-8 alkyl, C 1-8 alkyl, CN, C(O)R 13 , C 6-10 aryl, heterocycle, C 3-8 cycloakyl, C 3-8 cycloalkenyl, NR 14 R 15 or hydroxyl; R 11 is H or C 1-8 alkyl; R 12 is OPO 3 H 2 , carboxylic acid, PO 3 H 2 , C 1-6 alkyl, —S(O) 2 H, —P(O)MeOH, —P(O)(H)OH or OR 16 ; R 13 is H, OH or C 1-8 alkyl; R 14 is H or C 1-8 alkyl; R 15 is H or C 1-8 alkyl; R 16 is H or C 1-8 alkyl; L 1 is O, S, NH or CH R 16 ; L 2 is O, S or CH R 16 ; L 3 is O, S or CH R 16 ; a is 1, 2, 3, 4, 5 or 6; b is 0 or 1; c is 1, 2, 3, 4 or 5.