Patent ID: 8158654

Claim:
A compound of the formula: wherein one of W and V is N and the other is C; X is selected from the group consisting of cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl, and heterocycloalkylalkyl, wherein the ring portion of each is optionally substituted with one, two, three, four or five substituents independently selected from the group consisting of halo, alkyl, alkoxy, hydroxyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, cyano, nitro, alkylamino, dialkylamino, thiol, alkylthiol, haloalkyl, carboxy and alkylcarboxy; Y is selected from the group consisting of S, O, CH(CH 3 ), CH(OH), C(CH 3 )(OH), C(CH 3 ) 2 , C(—U(CH 2 ) n U—), C(O), S(O), and S(O) 2 ; n is an integer from 1 to 3; U is selected from the group consisting of CH 2 , S, and O; Z is selected from the group consisting of H, alkyl optionally substituted with a substituent selected from the group consisting of halo, alkyl, alkoxy, hydroxyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, cyano, nitro, amino, alkylamino, dialkylamino, thiol, alkylthiol, haloalkyl, carboxy, alkylcarboxy and carbamoyl; cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl, and heterocycloalkylalkyl, wherein the ring portion of each is optionally substituted with one, two, three, four or five substituents independently selected from the group consisting of halo, alkyl, alkoxy, hydroxyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, cyano, nitro, amino, alkylamino, dialkylamino, thiol, alkylthiol, haloalkyl, carboxy, alkylcarboxy and carbamoyl; and R 1 and R 2 are independently selected from the group consisting of H and alkyl.