Patent ID: 8563805

Claim:
A genetically modified apple plant, the fruit of said apple plant having reduced browning potential relative to said wild type, wherein the reduced browning potential results from the reduction in expression of genes encoding at least four polyphenol oxidase (PPO) isoenzymes in said apple plant relative to said wild type; or a genetically modified cell, seed, seedling, part, tissue, fruit or progeny of said plant, wherein said apple plant comprises: a first heterologous nucleic acid molecule comprising at least 100 contiguous nucleotides of a sequence possessing 100% sequence identity to SEQ ID NO: 18, that encodes a first PPO isoenzyme comprising the amino acid sequence set forth in SEQ ID NO: 19, which first heterologous nucleic acid molecule reduces expression of said first PPO isoenzyme; a second heterologous nucleic acid molecule comprising at least 100 contiguous nucleotides of a sequence possessing 100% sequence identity to SEQ ID NO: 20, that encodes a second PPO isoenzyme comprising the amino acid sequence set forth in SEQ ID NO: 21, which second heterologous nucleic acid molecule reduces expression of said second PPO isoenzyme; a third heterologous nucleic acid molecule comprising at least 100 contiguous nucleotides of a sequence possessing 100% sequence identity to SEQ ID NO: 22, that encodes a third PPO isoenzyme comprising the amino acid sequence set forth in SEQ ID NO: 23, which third heterologous nucleic acid molecule reduces expression of said third PPO isoenzyme; and a fourth heterologous nucleic acid molecule comprising at least 100 contiguous nucleotides of a sequence possessing 100% sequence identity to SEQ ID NO: 24, that encodes a fourth PPO isoenzyme comprising the amino acid sequence set forth in SEQ ID NO: 25, which fourth heterologous nucleic acid molecule reduces expression of said fourth PPO isoenzyme; and wherein said genetically modified cell, seed, seedling, part, tissue, fruit or progeny of said plant comprises said first, second, third, and fourth heterologous nucleic acid molecule.