Patent ID: 8476289

Claim:
A compound of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereo-chemically isomeric forms thereof, wherein each n is an integer with value 0, 1 or 2 and when n is 0 then a direct bond is intended; each m is an integer with value 1 or 2; X is independently N or CH; A is hydroxy or a radical of formula: R 1 is hydrogen, C 1-6 alkyl, hydroxyC 1-6 alkyl, C 1-6 alkylsulfonyl, C 1-6 alkylcarbonyl or mono- or di(C 1-6 alkyl)aminosulfonyl; R 2 is hydrogen, hydroxy, amino, halo, C 1-6 alkyl, cyano, C 2-6 alkenyl, polyhaloC 1-6 alkyl, nitro, phenyl, C 1-6 alkylcarbonyl, hydroxycarbonyl, C 1-6 alkylcarbonylamino, C 1-6 alkyloxy, or mono- or di(C 1-6 alkyl)amino; R 3 is hydrogen, halo, C 1-6 alkyl, or C 1-6 alkyloxy; or when R 2 and R 3 are on adjacent carbon atoms, they can form the bivalent radical: —O—CH 2 —O— (a-2); R 4 is hydrogen, C 1-6 alkyl, C 1-6 alkyloxyC 1-6 alkyl, C 3-6 cycloalkyl, C 3-6 cycloalkylmethyl, phenylC 1-6 alkyl; or when R 2 is on the 7-position of the indolyl then R 2 and R 4 together can form the bivalent radical; —(CH 2 ) 2 — (a-3), or —(CH 2 ) 3 — (a-4); R 5 is hydrogen or thiophenyl.