Patent ID: 8492111

Claim:
An arylalkylamine compound represented by the formula [I-e]: the symbols in the formula represent the following meanings: Ar: represents naphthyl optionally substituted by one or more groups selected from the group consisting of halogen, hydroxy, cyano, halo-lower alkyl, lower alkyl, lower alkoxy and lower alkylthio; R 1 : represents a monocyclic heterocyclic group selected from pyrrolyl, thienyl, thiazolyl, piperidyl, piperazinyl, morpholinyl, pyridyl, pyrimidinyl, pyradinyl and pyridazinyl, each of which is optionally substituted by substituent(s) selected from the following Substituent group Q1: <Substituent group Q1> halogen cyano nitro oxo group hydroxy carboxy optionally substituted lower alkyl which may be optionally substituted by 1 or plural groups selected from halogen, cyano, nitro, oxo, carboxy, hydroxy, lower alkoxy and halo-lower alkoxy optionally substituted lower alkoxy which may be optionally substituted by 1 or plural groups selected from halogen, cyano, nitro, oxo, carboxy and hydroxy optionally substituted amino which may be mono- or di-substituted by a group selected from lower alkyl, and halo-lower alkyl optionally substituted 5 to 6-membered monocyclic heterocyclic group which may be optionally substituted by 1 or plural groups selected from halogen, cyano, nitro, oxo, carboxy, hydroxy, lower alkyl, halo-lower alkyl, lower alkoxy, halo-lower alkoxy and acyl optionally substituted phenyl which may be optionally substituted by 1 or plural groups selected from halogen, cyano, nitro, oxo, carboxy, hydroxy, lower alkyl, halo-lower alkyl, lower alkoxy, halo-lower alkoxy and acyl acyl; n: is an integer of 1 to 3; X: represents single bonding arm; or a pharmaceutically acceptable salt thereof, provided that compounds wherein Ar represents optionally substituted naphthyl; R 1 represents an optionally substituted phenyl; and n is 2; or pharmaceutically acceptable salts thereof, are excluded.