Patent ID: 7384930

Claim:
A compound of Formula I wherein: R 1 is C 1-6 alkyl, C 2-6 alkenyl, C 3-7 cycloalkyl, C 5-7 cycloalkenyl, (C 3-7 cycloalkyl)C 1-6 alkyl, C 1-6 haloalkyl, (C 1-6 alkoxy)alkyl, C 1-6 alkyl, (Ar 1 )C 1-6 alkyl, (NR 7 R 8 )C 1-6 alkyl, N—(R 9 )-pyrrolidinyl or N—(R 9 )-piperidinyl; R 2 and R 3 taken together are CHNNR 5 ; R 4 is hydrogen, halo or C 1-6 alkyl, or C 2-6 alkenyl; R 5 is hydrogen or C 1-6 alkyl; R 6 is hydrogen, C 1-6 alkyl, or NR 5 R 6 taken together is R 7 is hydrogen or C 1-6 alkyl; R 8 is hydrogen or C 1-6 alkyl; or NR 7 R 8 taken together is selected from the group consisting of pyrrolidinyl, piperidinyl, N—(R 9 )-piperazinyl, morpholinyl, and thiomorpholinyl; R 9 is hydrogen, C 1-6 alkyl, C 1-6 alkylcarbonyl, or C 1-6 alkoxycarbonyl; R 10 is phenyl, naphthyl, pyridinyl, pyridinyl N-oxide, quinolinyl, quinolinyl N-oxide, isoquinolinyl, or isoquinolinyl N-oxide, and is substituted with 0-2 substituents selected from the group consisting of halo, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 alkoxy, hydroxy, and phenyl; or R 10 is selected from the group consisting of each R 11 is independently hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, or C 1-6 alkoxy; Ar 1 is phenyl, naphthyl, pyridinyl, or imidazolyl, and is substituted with 0-2 substituents selected from the group consisting of halo, C 1-6 alkyl, and C 1-6 haloalkyl; Ar 2 is phenyl, naphthyl, or pyridinyl, and is substituted with 0-2 substituents selected from the group consisting of halo, C 1-6 alkyl, and C 1-6 haloalkyl; X-Y is aminocarbonyl, oxycarbonyl, methylenecarbonyl, ethylene, or amino(cyano)iminomethyl; Z is N or CH; and n is 1; or a pharmaceutically acceptable salt thereof.