Patent ID: 8470970

Claim:
An isolated or recombinant polypeptide, wherein the polypeptide comprises an extracellular region and a transmembrane region, wherein (a) the extracellular region is selected from the group consisting of: an amino acid sequence that has at least 93% amino acid sequence identity to the extracellular region of SEQ ID NO:20 or an amino acid sequence that has at least 94% amino acid sequence identity to the extracellular region of SEQ ID NO:23, or an amino acid sequence of an extracellular region of another GPCR, and (b) the transmembrane region is selected from the group consisting of: an amino acid sequence that has at least 93% amino acid sequence identity to the transmembrane region of SEQ ID NO:20 or has at least 94% amino acid sequence identity to the transmembrane region of SEQ ID NO:23, or an amino acid sequence of a transmembrane region of another GPCR, wherein at least one of the extracellular region and the transmembrane region comprises at least 93% amino acid sequence identity to the extracellular region or the transmembrane region of SEQ ID NO:20 or at least 94% amino acid sequence identity to the extracellular region or the transmembrane region of SEQ ID NO:23.