Patent ID: 8013144

Claim:
A heterogeneous nuclear ribonucleoprotein K expression-inhibiting compound, which is a nucleotide-based molecule having a sense region and an antisense region jointly forming a duplex region, wherein each of said sense region and said antisense region has a length of 18-30 nucleotides, and wherein said antisense region containing a sequence matching with a sequence of an mRNA of heterogeneous nuclear ribonucleoprotein K and inhibiting expression of heterogeneous nuclear ribonucleoprotein K and suppress growth, metastasis and invasion of cancer cells, wherein a sequence of said sense region is expressed by UAAACGCCCUGCAGAAGAUUU (SEQ ID NO: 1) GGUCGUGGCUCAUAUGGUGUU (SEQ ID NO: 2) UGACAGAGUUGUUCUUAUUUU (SEQ ID NO: 3) GCAAGAAUAUUAAGGCUCUUU (SEQ ID NO: 4).