Patent ID: RE39760

Claim:
A monoclonal antibody specific for a purified human colon carcinoma-associated protein antigen, wherein said antigen has the following characteristics: (a) said antigen is purified to the extent that the membrane fractions are free of HL-A antigen and are substantially free from non-immunogenic glycoprotein fractions; (b) said antigen is not detectable on normal colon cancer free human tissues; (c) said antigen is not detectable on human carcinoma cells other than colon carcinoma cells; (d) said antigen is specifically immunogenic in humans; and (e) said antigen induces an immune response in humans having colon carcinoma which is expressed as cell mediated immunity which is murine monoclonal antibody 33 . 28 as produced by hybridoma PCA 33 . 28 , deposited with the American Type Culture Collection and assigned accession number PTA- 5413 .