Patent ID: 7442515

Claim:
A device for binding cells or molecules, wherein the device comprises: (a) a body defining a first surface and a second surface that is located opposite to the first surface; (b) multiple heaters disposed upon the first surface, wherein some or all of the heaters are independently controllable; and (c) a temperature-responsive layer disposed upon the second surface, wherein the temperature-responsive layer is deposited by plasma deposition at a first high deposition power and at least one second low deposition power, and comprises a temperature-responsive material having a first layer that crosslinks and adheres to the second surface at the first high deposition power and at least one second layer that forms at the at least one second low deposition power that can exist in a first state that binds molecules or living cells, and can exist in a second state that binds substantially less molecules or living cells than the first state, and wherein the temperature-responsive material is reversibly convertible to the first state from the second state in response to an effective amount of thermal energy.