Patent ID: 7119122

Claim:
A compound of formula (I) wherein: A represents a phenyl ring or A represents a C8 to 10 aromatic or partially aromatic bicyclic ring system; R 1 represents C1 to 6 alkyl, C1 to 6 alkoxy, halogen, hydroxy, cyano, trifluoromethyl or NR 6 R 7 ; R 3 represents hydrogen, C1 to 6 alkyl, C2 to 6 alkenyl, C3 to 6 cycloalkyl, C1 to 6 alkylthio, C1 to 6 alkoxy, halogen, hydroxy, cyano, trifluoromethyl or NR 8 R 9 ; said alkoxy group being optionally further substituted by hydroxy or by one or more fluorine atoms; or R 3 represents phenyl or a five- or six-membered aromatic heterocyclic ring containing 1 to 3 heteroatoms independently selected from O, S and N; said phenyl or aromatic heterocyclic ring being optionally substituted by one or more substituents selected independently from halogen, C1 to 4 alkyl, C1 to 4 alkoxy, hydroxy, cyano or NR 8 R 9 ; said alkyl or alkoxy group being optionally further substituted by one or more fluorine atoms; R 4 and R 5 independently represent hydrogen or C1 to 6 alkyl; said alkyl group being optionally substituted by OH, C1 to 6 alkoxy, NR 10 R 11 or phenyl; said phenyl group being optionally further substituted by C1 to 6 alkyl, C1 to 6 alkoxy, halogen, hydroxy, cyano or NR 12 R 13 ; R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 and R 13 independently represent hydrogen or C1 to 6 alkyl; said alkyl group being optionally substituted by OH or C1 to 6 alkoxy; or the groups NR 4 R 5 , NR 6 R 7 and NR 8 R 9 independently represent a 4- to 7-membered saturated azacyclic ring optionally incorporating one further heteroatom selected from O or N; said ring being optionally substituted by OH, C1 to 3 hydroxyalkyl or C1 to 3 alkoxy; V represents cyano or nitro; X represents O or S(O) n ; n represents an integer 0, 1 or 2; Y represents C1 to 6 alkyl; each of T, U and W represents CR 2 ; and each R 2 group independently represents hydrogen, C1 to 3 alkyl, C1 to 3 alkoxy or halogen; or a pharmaceutically acceptable salt thereof; with the provisos 1) that when A represents phenyl, V represents nitro, Y represents CH 2 , X represents S, and the group Y—NR 4 R 5 is bonded to the phenyl ring ortho to X, then R 4 and R 5 do not both represent CH 3 , 2) that when V represents CN, X represents S, Y represents C1 alkyl, R 3 represents H, and R 4 and R 5 both represent C1 alkyl, then R 1 cannot represent a C1 alkyl, and 3) that when R 1 represents Cl, V represents NO 2 , X represents O, and R 3 , R 4 and R 5 represent H, then Y cannot represent a C2 alkyl.