Patent ID: 7636502

Claim:
An optical waveguide bio-sensing device, comprising: a light source, capable of emitting a monochromatic light; a grating chip, comprising at least a grating structure and a waveguide layer on the grating structure for receiving the monochromatic light, wherein a receptor is provided on the waveguide layer and a sample substance is coated on the grating chip; a beam splitter, disposed between the light source and the grating chip for the monochromatic light to transmit therethrough or to be reflected thereby to generate a reflected light; and a sensor, for detecting the reflected lights; wherein the waveguide layer comprises at least one of silicon nitride, gallium nitride, tantalum oxide, indium-tin oxide, indium-gallium arsenide, gallium arsenide, indium phosphide, gallium arsenide-antimonide, magnesium fluoride, zinc sulfide, zinc telluride, beryllium-zinc telluride, magnesium selenide, aluminum-gallium nitride, aurum, argentum, sulfhydryl (HS), amine (NH2), aldehyde (CHO), carboxyl (COOH), biotin and combination thereof; wherein the grating structure has a depth within a range from 50 nm to 2 μm and a line-width both within a range from 50 nm to 2 μm.