Patent ID: 7153520

Claim:
A liquid polymeric composition for the sustained delivery of a poorly water-soluble drug comprising: i) an amphiphilic diblock copolymer; ii) a poorly water-soluble drug; iii) a biodegradable polymer; and, iv) liquid poly(ethylene glycol); wherein said amphiphilic diblock copolymer, said poorly water-soluble drug and said biodegradable polymer are dissolved or dispersed in said liquid poly(ethylene glycol); and wherein said composition is an injectable liquid at a room temperature and, upon being injected into a body, forms an implant containing polymeric micelles wherein said poorly water-soluble drugs are physically trapped and wherein said amphiphilic diblock copolymer is composed of a hydrophilic polyalkylene glycol block selected from the group consisting of polyethylene glycol, monoalkoxypolyethylene glycol and monoacyloxypolyethylene glycol and a hydrophobic biodegradable polymer block selected from the group consisting of polylactides, polycaprolactone, poly(lactide-co-glycolide), poly(lactide-co-caprolactone), poly(lactide-co-p-dioxanone), polyorthoesters, polyanhydrides, poly(amino acid) and polycarbonates.