Patent ID: 8417313

Claim:
A method for generating a database table of surface charge densities (ρ) that embody an ionic nature of cellular membranes across an endocardium of at least one given heart chamber, the cellular membrane surface charge density information comprising a table ρ(P′, t) wherein: i) a position P′=(x′,y′,z′) of a point on the cellular membrane of the endocardial wall in a heart chamber is defined in x, y, z-coordinates, ii) t is a time of measurement for said cellular membrane surface charge density, and iii) ρ is the cellular membrane surface charge density at said time t and said position P′ derived from a measured electric potential from the heart chamber, the method comprising the following steps: a) determining electric potential data V e at locations P in the heart chamber at a given time t using a probe electrode of a mapping system, b) transforming the electric potential data V e into said cellular membrane surface charge density ρ(P′,t) at positions P′ on the endocardial wall using a processor executing a set of conversion instructions stored in a computer memory, and c) storing each cellular membrane surface charge density in the computer memory as a table of cellular membrane surface charge densities.