Patent ID: 7671045

Claim:
A compound of formula (II) wherein m is an integer from 0 to 3; R 10 is selected from the group consisting of hydroxy, halogen, C 1-3 alkyl, C 1-3 alkoxy, cyano, nitro, amino, (C 1-4 alkylamino) and di(C 1-4 alkyl)amino; Y is selected from the group consisting of O and S; R 11 and R 12 are each independently selected from the group consisting of hydroxy, C 1-4 alkyl, —CH(—O—C 1-4 alkyl) 2 , C 1-4 alkoxy, halogenated C 1-4 alkyl, halogenated C 1-4 alkoxy, phenyl, —O-phenyl, —O-aralkyl, 2-isoxazolidin-3-one and NR 15 R 16 ; wherein the phenyl, whether alone or as part of a substituent group, is optionally substituted with one or more substituents independently selected from hydroxy, carboxy, halogen, C 1-3 alkyl, C 1-3 alkoxy, cyano, nitro, amino, (C 1-4 alkylamino) and di(C 1-4 alkyl)amino; wherein R 15 and R 16 are each independently selected from the group consisting of hydrogen and C 1-4 alkyl; alternatively, R 15 and R 16 are taken together with the nitrogen atom to which they are bound to form a 5- to 7-membered saturated or partially unsaturated nitrogen containing heterocyclyl ring; wherein the nitrogen containing heterocyclyl ring is optionally substituted with one or more substituents independently selected from hydroxy, carboxy, C 1-4 alkyl, C 1-4 alkoxy, nitro, cyano, amino, (C 1-4 alkylamino) and di(C 1-4 alkyl)amino; alternatively, R 11 and R 12 are taken together with the phosphorous atom to which they are bound to form a 5- to 7-membered saturated phosphorous containing heterocyclyl ring; wherein the phosphorous containing heterocyclyl ring is optionally substituted with one or more substituents independently selected from hydroxy, carboxy, C 1-4 alkyl, C 1-4 alkoxy, nitro, cyano, amino, (C 1-4 alkylamino) and di(C 1-4 alkyl)amino; R 13 is selected from the group consisting of —NR 17 R 18 ; —O—R 19 and —S(O) 0-2 —R 20 ; wherein R 17 and R 18 are each independently selected from the group consisting of hydrogen and C 1-4 alkyl; alternatively, R 17 and R 18 are taken together with the nitrogen atom to which they are bound to form a 5- to 7-membered saturated nitrogen containing heterocyclyl ring; wherein the nitrogen containing heterocyclyl ring is optionally substituted with one or more substituents independently selected from the group consisting of hydroxy, carboxy, C 1-4 alkyl, C 1-4 alkoxy, nitro, cyano, amino, (C 1-4 alkylamino) and di(C 1-4 alkyl)amino; R 19 is selected from the group consisting of C 1-4 alkyl, —C(O)—C 1-4 alkyl and —C(O)-phenyl; R 20 is selected from the group consisting of hydrogen and C 1-4 alkyl; or a pharmaceutically acceptable salt, ester or prodrug thereof.