Patent ID: 7265134

Claim:
A compound of Formula I or a pharmaceutically acceptable salt or stereoisomer thereof, wherein X is: C—H; one n is 1 and one n is 2; t is: 1 through 6; R 1 is: 1) H, 2) halo, 3) C 1-6 alkyl, or 4) OC 1-6 alkyl; R 2 is: 1) aryl, optionally substituted with one to three substituents selected from: a) halo, b) OC 1-3 perfluoroalkyl, c) OC 1-6 alkyl, d) CN, e) OH, f) SO 2 R d , g) C 1-6 alkyl, h) i) (C═O)R d , and i) CO 2 R d , 2) CN, 3) (C═O)NR a R b , 5) C 3-6 cycloalkyl, or 6) —C≡C—R c ; R 3 is: 1) H, 2) C 1-8 alkyl, 3) SO 2 R d , 4) (C═O)R d , or 5) CO 2 R d ; R 3a is: 1) H, 2) SO 2 R d , 3) heterocyclyl, 4) (C═O)R d , 5) CO 2 R d , or 6) C 1-8 alkyl, said alkyl is optionally substituted with one to three substituents selected from oxo, heterocyclyl, halo, NR 5 R 6 , CO 2 H, CO 2 R d , CONR 5 R 6 , OH and OC 1-6 alkyl; R 4 is: 1) H, 2) C 0-6 alkylene-NR 5 R 6 , 3) CO 2 H, 4) CO 2 R d , 5) halo, 6) OH, 7) C 1-8 alkoxy, or 8) C 1-8 alkyl, said alkyl is optionally substituted with one to three substituents selected from oxo, heterocyclyl, halo, NR 5 R 6 , CO 2 H, CO 2 R d , CONR 5 R 6 , OH and OC 1-6 alkyl; R 5 and R 6 are independently: 1) H, 2) C 1-8 alkyl, 3) SO 2 R d , 4) CO 2 R d , 5) (C═O)R d , 6) C 1-8 alkylene-NR a R b , 7) C 1-8 alkylene-(CO)NR a R b , 8) C 1-8 alkylene-heterocyclyl, or 9) aryl, said aryl and heterocyclyl optionally substituted with one or more substituents selected from C 1-6 alkyl, C 1-3 perfluoroalkyl, C 1-6 alkoxy, OCF 3 , SO 2 R d , NR a R b and halo; or R 5 and R 6 are taken with the nitrogen to which they are attached to form a monocyclic or bicyclic heterocycle with 5-7 members in each ring, said heterocycle optionally substituted with one or more substituents selected from halo, C 1-6 alkyl, OC 1-6 alkyl, OCF 3 , CO 2 R d , (C═O)R d , aryl, heterocyclyl, SO 2 R d and OH; R a and R b are independently: 1) H, 2) C 1-6 alkyl, 3) C 3-6 cycloalkyl, 4) phenyl, 5) CO 2 R d , 6) (C═O)R d , or 7) SO 2 R d ; R c is H, phenyl, or C 1-6 alkyl; and R d is phenyl or C 1-6 alkyl.