Patent ID: 7628920

Claim:
A method of separating analytes contained within a sample, wherein said sample has one or more enantiomeric analytes, comprising: providing a reagent having a chiral mobile phase with the formula: wherein R 1 -R 4 are all different, and wherein the individual R group is selected from the group consisting of hydrogen, alkanes, alkenes, alkyl groups for example C 1 -C 24 and greater, aryl, arylalkyl, hydroxyl, halogens, esters, ethers, alcohols, saturated and/or unsaturated hydrocarbons, branched and/or unbranched hydrocarbons, amines, amidines, amides, ketone, acetone, dienes, carboxyl, sulfhydrals, sulfates, sulfonates, sulfur, enols, and combinations thereof wherein said chiral mobile phase is selected from the group consisting of 2-butanol, 2-butylamine, 3-amino-1,2-propanediol, 1-amino-2-propanol, 2-amino-1-propanol, 1-dimethylamino-2-propanol, 1,2-propanediol, propylene carbonate, 1,2-diaminopropane dihydrochloride, 1-methyl-2-pyrrolidone, methyl-2-pyrrolidone-5-carboxylate, 1,2-dichloropropane, 2-bromopropionic acid, 2-bromopropionitrile, 2-chloropropionic acid, 2-chloropropionitrile, epichlorohydrin, 3-chloro-2-methylpropionitrle, 1-bromo-3-chloro-2-methylpropane, propylene oxide, 1,2propanediol diacetate, 1-methoxy-2-propanol, 1-methoxy-2-propanol acetate, 1,2-diamino propane, 3-aminopyrrolidine, 4-chloro-3-hydroxy butyronitrile, 1-chloro-2-propanol, 2-chloro-l-propanol, methyl-2,3-dichloropropionate, 2-butanol, 1,2,4-butanetriol, 1,3-butanediol, 2,3-butanediol, β-hydroxy-γ-butyrolactone, 3-chloro-2-butanone, 4-chloromethyl-2,2-dimethyl-1,3-dioxolane, 1-chloro-2-methylbutane, methyl-2-chloropropionate, and 3-hydoxy pyrrolidine; introducing said sample into a means for separation; and contacting said sample with said chiral mobile phase resulting in an admixture.