Patent ID: 8105491

Claim:
An extracorporeal filtration method, the method comprising the steps of: (a) drawing blood from a patient; (b) separating ultrafiltrate fluid from cellular components of said blood; (c) optionally, infusing said separated ultrafiltrate fluid with glucose; (d) infusing oxygen into the separated ultrafiltrate fluid; (e) treating said separated ultrafiltrate fluid independently of said cellular components in a recirculation circuit, wherein said treating comprises circulating said separated ultrafiltrate fluid through an active cartridge comprising active cells operative to effectuate a selected treatment of said separated ultrafiltrate fluid, wherein said active cells are the C3A cell line; (f) recombining said treated ultrafiltrate fluid and said cellular components; and (g) returning whole blood comprising said recombined, treated ultrafiltrate fluid and said cellular components to the patient, with the proviso that said separated ultrafiltrate fluid is analyzed either prior or subsequent to said treating step (e) but before said recombining step (f), wherein the analysis comprises monitoring of oxygen and pH differentials across the active cartridge.