Patent ID: 7754679

Claim:
A pharmaceutical composition comprising: (i) an amino acid ester of formula: wherein R is the amino acid side chain; and R 1 is a C 1 to C 22 hydrocarbon group; or an amino acid amide of general formula: wherein R is the amino acid side chain; R 3 is a C 1 to C 22 hydrocarbon group; and R 4 is hydrogen or a C 1 to C 22 hydrocarbon group; and (ii) a protonated aptamer, which is conjugated to polyethylene glycol; and (iii) a pharmaceutically acceptable organic solvent, wherein the protonated aptamer is dissolved in the pharmaceutically acceptable organic solvent to provide a concentration of the aptamer in the pharmaceutically acceptable organic solvent of at least 2 percent by weight of the pharmaceutical composition or about 2 percent by weight of the pharmaceutical composition, and wherein the composition is suitable for administration to an animal by injection.