Patent ID: 7066900

Claim:
An electrophoresis system for removing or reducing concentration of a metabolic component from blood or plasma of a subject, comprising: (a) a first ion-permeable barrier having a defined pore size and pore size distribution disposed in an electric field area; (b) a second ion-permeable barrier having defined pore size and pore size distribution disposed between a cathode zone and the first barrier so as to define a treatment chamber therebetween; (c) means adapted for cooling blood or plasma from the subject; (d) means adapted to provide dialysate to the cathode zone and an anode zone; (e) means adapted to provide blood or plasma from the subject to the treatment chamber; wherein, upon application of the electric potential, a metabolic component from the blood or plasma moves through at least one barrier into at least one of the cathode or anode zones, and wherein the barriers forming the treatment chamber are provided as a cartridge or cassette positioned between the electrode zones of the system.