Patent ID: 7422607

Claim:
A process comprising the steps of: i. providing a biological tissue, ii. fixing the tissue with a fixative; iii. treating the tissue with an agent that creates a hydrophobic environment on said tissue wherein said hydrophobic environment prevents calcification of said tissue while retaining biocompatibility wherein the agent is selected from the group consisting of a siloxane dialdehyde of the structure a dialdehyde of the structure a siloxane diamine of the structure and a siloxane monoamine of the structure wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are chosen from the group consisting of alkyl, phenyl, benzyl, and cyanoethyl; wherein n=1 to 100; wherein x and x′=2 to 30; and wherein R 8 , R 9 and R 10 are chosen from the group consisting of alkyl chains, partially fluorinated alkyl chains, perfluoroalkyl chains, polyether chains and siloxane chains.