Patent ID: 6916487

Claim:
A transdermal drug delivery system comprising: (a) a therapeutically effective amount of an antiemetic agent; (b) at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen of formula (I): wherein R 1 is hydrogen, lower alkyl, lower alkoxy, halide, hydroxy or NR 3 R 4 ; R 2 is a C 8 to C 18 alkyl; R 3 and R 4 are each independently hydrogen, lower alkyl or R 3 and R 4 together with the nitrogen atom to which they are attached form a 5- or 6-membered heterocyclic ring; n is 0 or 1, and q is 1 or 2, wherein, when n is 0 and R 1 is NR 3 R 4 , then NR 3 R 4 is para-substituted, and wherein said dermal penetration enhancer is present in an amount of from about 10 to about 10,000 wt % based on the weight of the an antiemetic agent; and (c) at least one volatile liquid.