Patent ID: 7109220

Claim:
A compound of Formula (I): wherein: R 1 is selected from: (1) hydrogen; (2) aryl optionally substituted with (a) one or more substituents independently selected from C 1-8 alkyl, C 1-8 alkoxy, amino optionally mono or disubstituted with C 1-8 alkyl, cyano, halogen, halogen-substituted C 1-8 alkyl, halogen-substituted C 1-8 alkoxy, hydroxy or nitro; (b) one —SO 2 -amino substituent optionally mono or disubstituted on amino with C 1-8 alkyl, C 1-8 alkylamino optionally mono or disubstituted on amino with C 1-8 alkyl, C 1-8 alkyl-aryl, C(O)O-t-butyl or heteroaryl; (c) one —SO 2 -heterocyclyl substituent; (d) one —NHSO 2 -aryl substituent; (e) one —C(O)amino substituent optionally mono or disubstituted on amino with C 1-8 alkyl; (f) one —NHC(O)— substituent terminating with C 1-8 alkyl or aryl; (g) one —CO 2 — substituent terminating with hydrogen or C 1-8 alkyl; (h) one —NHC(O)NH-aryl substituent; or, (i) one —NHC(S)NH-aryl substituent; (j) one substituent selected from heterocyclyl selected from piperidinyl, piperazinyl, morpholinyl, thiomorpholinyl, or tetra-hydro-pyridazinyl, aryl or heteroaryl selected from pyrrolyl, oxazolyl, thiazolyl, imidazolyl, pyrazolyl, isoxazolyl or isothiazolyl; (3) heteroaryl optionally substituted with one or more substituents independently selected from C 1-8 alkyl, C 1-8 alkoxy, amino optionally mono or disubstituted with C 1-8 alkyl, cyano, halogen, halogen-substituted C 1-8 alkyl, halogen-substituted C 1-8 alkoxy, hydroxy or nitro; (4) —C(O)— terminating with aryl, heteroaryl or alkyl; (5) —C(O)NH— substituent terminating with aryl, heteroaryl or alkyl; or, (6) —C(S)NH— substituent terminating with aryl, heteroaryl or alkyl; R 2 is selected from hydrogen, C 1-8 alkoxy, amino optionally mono or disubstituted with C 1-8 alkyl, cyano, halogen, hydroxy, mercapto, S(C 1-8 )alkyl or nitro; wherein C 1-8 alkyl and C 1-8 alkoxy, whether alone or as part of a substituent group are optionally substituted with one or more substituents independently selected from halogen or amino optionally mono or disubstituted on amino with C 1-8 alkyl; R 3 is selected from aryl or heteroaryl, (1) wherein aryl is optionally substituted with one or more substituents independently selected from C 1-8 alkyl, C 1-8 alkoxy, amino optionally mono or disubstituted with C 1-8 alkyl, cyano, halogen, halogen-substituted C 1-8 alkyl, halogen-substituted C 1-8 alkoxy, hydroxy or nitro; and (2) wherein heteroaryl is optionally substituted on (a) a ring carbon atom with one or more substituents selected from C 1-8 alkyl, C 1-8 alkoxy, amino optionally mono or disubstituted with C 1-8 alkyl, cyano, halogen, halogen-substituted C 1-8 alkyl, halogen-substituted C 1-8 alkoxy, hydroxy or nitro; or on (b) a ring nitrogen atom with one C 1-8 alkyl substituent, or a pharmaceutically acceptable form thereof.