Patent ID: 7470538

Claim:
A method for improving blood flow to an ischemic myocardium having an area of viable myocardium in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of enriched CD133 + /CD34 + /CXCR4 − cells isolated from umbilical cord blood, wherein the enriched CD133 + /CD34 + /CXCR4 − cells are administered by infusion into a coronary artery, wherein administering of the CD133 + /CD34 + /CXCR4 − cells results in improved blood flow to said ischemic myocardium, wherein the CD133 + /CD34 + /CXCR4 − cells are enriched from umbilical cord blood mononuclear cells at least two-fold prior to administration to the subject.