Patent ID: 8404233

Claim:
An antibody capable of binding to human delta-like ligand 4 (DLL4), which antibody comprises (a) a light chain complementarity determining region (CDR) 1 comprising the amino acid sequence RASSSVSFMH (SEQ ID NO: 6); (b) a light chain CDR 2 comprising the amino acid sequence ATSNLTS (SEQ ID NO: 7); (c) a light chain CDR3 comprising the amino acid sequence QQWSSNPFT (SEQ ID NO: 8); (d) a heavy chain CDR1 comprising the amino acid sequence SYVMH (SEQ ID NO: 3); (e) a heavy chain CDR2 comprising the amino acid sequence YIIPYNDGTKYNEKFKG (SEQ ID NO: 4); and (f) a heavy chain CDR3 comprising the amino acid sequence SEDYDHFDY (SEQ ID NO: 5).