Patent ID: 7122310

Claim:
A method for forming a self-assembly substance comprising the steps of: providing a first group and a second group, wherein each group includes a pair of dimer forming probes containing a pair of oligonucleotides No. 1 and No. 2, each oligonucleotide having three regions of a 3′ side region, a mid-region and a 5′ side region, in which the mid-regions of the oligonucleotides No.1 and No.2 have base sequences complementary to each other, and the 3′ side regions and the 5′ side regions of the oligonucleotides No.1 and No. 2 have base sequences not complementary to each other, wherein the pair of dimer forming probes for the first group and the second group are different, and wherein (a) the 3′ side region of the oligonucleotide No. 1 of the first group and the 3′ side region of the oligonucleotide No. 2 of the second group, (b) the 5′ side region of the oligonucleotide No. 2 of the first group and the 5′ side region of the oligonucleotide No. 1 of the second group, (c) the 3′ side region of the oligonucleotide No. 1 of the second group and the 3′ side region of the oligonucleotide No. 2 of the first group, and (d) the 5′ side region of the oligonucleotide No. 2 of the second group and the 5′ side region of the oligonucleotide No. 1 of the first group, have base sequences complementary to each other, respectively; providing formed dimer-probes prepared by previously hybridizing a plurality of pairs of the dimer forming probes of the first and second groups to form the dimer-probes; hybridizing the formed dimer-probes of each group; and forming a double-stranded self-assembly substance by self-assembly of the oligonucleotides.