Patent ID: 8304229

Claim:
A process for preparing a substrate (A) having thereon sites reactive with a molecular probe (D) having reactive groups thereon, the process comprising the steps of: (I) optionally forming a functional coating (B) on the substrate (A); (II) applying to the optionally coated substrate (A), a binder material (C) comprising at least one reactive site of Formula 1: where: R 1 , R 2 and R 3 are each hydrogen; R 4 is an organic group and is capable of linking to optionally coated substrate (A), or where substrate (A) has hydroxyl groups thereon, then R 4 is hydrocarbylhalogenosilanyl and is capable of linking directly to substrate (A); X 2 is O; and (III) covalently binding the reactive group of the molecular probe (D) to an activated ethylenically unsaturated double bond of at least one reactive site of Formula 1, where the covalent bond is formed by thermal, non photo-chemical addition.