Patent ID: 7618975

Claim:
A compound according to Formula VIb: or pharmaceutically acceptable salts thereof, wherein: R 1 is methyl or ethyl; R 5 is H or F; R 2 is halo, N 3 , NH 2 , C 1-6 alkyl, -thio-C 1-6 alkyl, C 2-8 alkynyl, C 1-6 alkoxy, halo-C 1-6 alkyl, hydroxy-C 1-6 alkyl, —C(O)O—C 1-6 alkyl, —N(R a )(R b ), N(R a )(R b )—C 1-6 alkyl-, wherein R a and R b are independently H, OH (R a and R b are not both OH), C 2-6 hydroxyalkyl, or C 1-6 alkyl, or R a and R b together with the nitrogen atom to which they are both linked form a 5 or 6-membered heterocycle selected from the group consisting of: tetrahydrofuranyl, pyranyl, piperidinyl, piperazinyl, pyrrolidinyl, imidazolidinyl, imidazolinyl, morpholinyl, pyrazolidinyl, pyrazolinyl, tetronoyl, and tetramoyl, wherein when R a and/or R b are C 1-6 alkyl, then R a and R b are independently optionally substituted with C 2-8 alkenyl or —N(R aa )(R bb ), wherein R aa and R bb are independently H, C 1-6 alkyl or R aa and R bb together with the nitrogen atom to which they are both linked form a 5 or 6-membered heterocycle selected from the group consisting of: tetrahydrofuranyl, pyranyl, piperidinyl, piperazinyl, pyrrolidinyl, imidazolidinyl, imidazolinyl, morpholinyl, pyrazolidinyl, pyrazolinyl, tetronoyl, and tetramoyl; R 3 , is H, halo, C 1-6 alkyl, or C 1-6 alkoxy; R 4 , is H, halo, C 1-6 alkyl, or C 1-6 alkoxy, N 3 , nitro, or —N(R a )(R b ), wherein R a and R b are independently H or C 1-6 alkyl; R 6 , is H, halo, or C 1-6 alkyl; R 7 , R 8 , R 10 , and R 11 are H, halo, or C 1-6 alkoxy; and R 9 is H, halo, N 3 , OH, nitro, NH 2 , C 1-6 alkyl, C 1-6 alkoxy optionally substituted with 1-3 halo substituents, thio-C 1-6 alkyl, —C(O)O—C 1-6 alkyl, —N(R a )(R b ), wherein R a and R b are independently H or C 1-6 alkyl wherein optionally R 9 and R 10 together form a 5 or 6-membered heterocycle selected from the group consisting of: tetrahydrofuranyl, pyranyl, piperidinyl, piperazinyl, pyrrolidinyl, imidazolidinyl, imidazolinyl, morpholinyl, pyrazolidinyl, pyrazolinyl, tetronoyl, and tetramoyl; provided that when R 9 is H then R 8 and R 10 are not both H or one H and the other halo.