Patent ID: 7538135

Claim:
A compound of the formula wherein R 1 and R 2 are independently hydrogen, halogen, hydroxy, optionally substituted alkyl, alkoxy, alkylthio, aralkyl or heteroaralkyl; or R 1 and R 2 combined together with the carbon atoms to which they are attached form an optionally substituted fused 5- to 6-membered aromatic or heteroaromatic ring provided that R 1 and R 2 are attached to carbon atoms adjacent to each other; or R 1 and R 2 combined are alkylene which together with the carbon atoms to which they are attached form a fused 5- to 7-membered ring provided that R 1 and R 2 are attached to carbon atoms adjacent to each other; or R 3 is hydrogen or optionally substituted lower alkyl; X is -Z-(CH 2 ) p -Q-W wherein Z is O, S, S(O), or S(O) 2 ; or p is an integer from 1 to 8; Q is a bond; R 8 is optionally substituted alkyl, aralkyl, alkoxy, alkylthio, —C(O)R 10 , —C(O)OR 11 or —C(O)NR 12 R 13 in which R 10 is optionally substituted lower alkyl; R 11 , R 12 and R 13 are independently hydrogen or optionally substituted lower alkyl; R 9 is hydrogen, optionally substituted alkyl, aryl or aralkyl; or a pharmaceutically acceptable salt thereof.