Patent ID: 7608271

Claim:
A modified anti-fusogenic peptide comprising a peptide that has been modified to have a maleimide containing group coupled thereto which is reactive with a thiol group at cysteine 34 of albumin, said peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1. SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 117, SEQ ID NO: 118, SEQ ID NO: 119, SEQ ID NO: 534, SEQ ID NO: 535, SEQ ID NO: 536, SEQ ID NO: 537, SEQ ID NO: 538, SEQ ID NO: 539, SEQ ID NO: 540, and SEQ ID NO: 541, wherein said maleimide containing group is attached to said peptide without a linker or via a (2-amino)ethoxy acetic acid (AEA) or a [2-(2-amino) ethoxy] acetic acid (AEEA) linker and said modified anti-fusogenic peptide exhibits an anti-viral and anti-fusogenic activity against human immunodeficiency virus (HIV).