Patent ID: 8706180

Claim:
An in vivo glucose sensor, comprising: a substrate having a distal region for partial implantation through a skin surface and a proximal region, the substrate including at least a first surface and a second surface; a working electrode disposed on the distal region of the first surface of the substrate and configured to be positioned in fluid contact with interstitial fluid under the skin surface; a counter electrode disposed on the distal region of the second surface of the substrate; a plurality of conductive contacts disposed on the proximal region of the substrate and on the first surface of the substrate, wherein a first one of the plurality of conductive contacts is in electrical communication with the work electrode, and a second one of plurality of conductive contacts is in electrical communication with the counter electrode; at least one via formed through the substrate that electrically connects the counter electrode to the second one of the plurality of conductive contacts; a sensing layer proximate to the working electrode; and a mass transport limiting layer proximate to the working electrode; wherein a flexibility of sensor is varied along a continuum of the substrate