Patent ID: 6960474

Claim:
A method for inhibiting the growth of hormone-dependent tumor cells in a patient in need thereof, comprising administering to said patient a selective androgen receptor modulator compound in an amount effective therefor, wherein: said selective androgen receptor modulator compound exhibits antagonist activity inhibiting growth of said hormone-dependent tumor; and wherein said selective androgen receptor modulator compound exhibits no activity or agonist activity against other, nontumor tissues containing the androgen receptor, wherein said no activity is maintaining at least one of average normal bone density, average normal muscle mass, average normal reproductive function, and average normal libido seen in ugonadal warm-blooded male mammals, wherein said agonist activity is having an activation effect greater than 5% in vivo as compared to control animals on the weights of at least one of ventral prostate, seminal vesicles, levator ani, and luteinizing hormone serum levels, and wherein said selective androgen receptor modulator compound binds to an androgen receptor ligand binding domain having the structural coordinates of Table A.