Patent ID: 7799791

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt, hydrate, ketal derivative or hemiketal derivative thereof, wherein: one of R 1 and R 2 is H, and the other is selected from OR 6 , SR 6 , NR 6 R 7 , N 3 , Me, Et, CF 3 , SOR 8 and SO 2 R 8 ; or R 1 and R 2 are both H; one of R 3 and R 4 is H, and the other is selected from tert-butylmethyl, iso-propylmethyl, sec-butyl, tert-butyl, cyclopentyl and cyclohexyl; or R 3 and R 4 are joined together with the adjacent backbone carbon atom to form a spiro-C 5 -C 6 cycloalkyl group; R 6 and R 7 are each independently selected from H, C 1-8 -alkyl and C 3-8 -cycloalkyl; or R 6 and R 7 together with the nitrogen atom to which they are attached form an alkylene group: wherein p is 1, 2, 3 or 4; R 8 is C 1-8 -alkyl or C 3-8 -cycloalkyl; R 9 is selected from the following: B, D and G are each independently selected from: CH, CMe, N and N-oxide ( N→O); E is selected from: O, S SO 2 , NH, NMe and N-oxide ( N→O); J, and R are independently selected from: CH, N and N-oxide ( N→O); and R 41 is 4-methylpiperazin-1-yl, or 4-(2-methoxyethyl)piperazin-1-yl.