Patent ID: 6919377

Claim:
A compound of Formula I or a pharmaceutically acceptable salt thereof wherein: Ar is substituted 1 to 3 times or Unsubstituted aryl or substituted 1-3 times or unsubstituted heteroaryl, which heteroaryl is from 5 to 14 atoms having from 1 to 2 heteroatoms selected from N, O, and S wherein the substituents are selected from the groups F, Cl, Br, I, OH, NH 2 , SH, CN, NO 2 , OCH 3 , OC(O)CH 3 , CF 3 , OCH 2 CH 2 OH, NHC(O)CH 3 , NHCH 3 , or N(CH 3 ) 2 ; d is an integer of from 1 to 2; q is an integer from 0 to 6; R 1 and R 2 are independently selected from the coup consisting of hydrogen, alkyl, OH, hydroxyalkyl, aminoalkyl, aralkyl, or N(R 4 )(R 5 ) Wherein R 4 and R 5 are independently selected from hydrogen, alkyl, aralkyl, heteroaryl, heteroarylalkyl, aminoalkyl, hydroxyalkyl and thioalkyl; R is hydrogen, alkyl, C(O)R 6 , C(O)OR 6 , C(O)NHR 6 , aralkyl, hydroxyalkyl, aminoalkyl, amino(hydroxy)alkyl, or carboxyalkyl, wherein R 6 is alkyl or aralkyl; Y is OH; X is independently selected from hydrogen or an electron withdrawing group; and * denotes cis or trans or a mixture thereof.