Patent ID: 7355047

Claim:
A compound having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein: R 1 is selected from the group consisting of hydrogen; an optionally substituted alkyl, and aralkyl; each R 2 is selected from the group consisting of hydrogen and optionally substituted alkyl; each R 3 is selected from the group consisting of hydrogen, optionally substituted alkyl; a group OR 11 and NR 12 R 13 ; R 5 , R 7 and R 8 are independently selected from the group consisting of hydrogen, an optionally substituted alkyl, and halogen; R 9 and R 10 are independently selected from the group consisting of hydrogen, optionally substituted alkyl, aralkyl, cycloalkyl and cycloaralkyl; or R 9 and R 10 are taken together with the nitrogen atom to which they are attached to form a heterocyclic ring; R 11 is selected from the group consisting of hydrogen, an alkali metal, a negative charge and optionally substituted alkyl; R 12 and R 13 are independently selected from the group consisting of hydrogen, optionally substituted alkyl, aralkyl, aryl, cycloalkyl and cycloaralkyl; or R 12 and R 13 are taken together with the nitrogen atom to which they are attached to form a heterocyclic ring; with the proviso that when R 9 and R 10 are taken together to form a piperazinyl ring, R 7 is Cl, R 3 is OR 11, R 11 is H, R 5 and R 8 are H, then R 1 is not Et; with the further proviso that when R 9 and R 10 taken together to form 4-methylpiperazine, R 7 is Cl, R 3 is OR 11, R 11 is H, and R 5 and R 8 are H, then R 1 is not Et; and with the further proviso that when R 9 and R 10 are taken together to form a morpholinyl ring, R 1, R 2, R 5, R 7, R 8 are H, R 3 is NR 12 R 13 and either R 12 or R 13 is H, the other is not n-butyl.