Patent ID: 8641689

Claim:
A transdermal permeant delivery system comprising: i) a disposable substrate defining a poration area and having an upper substrate surface, a lower substrate surface, a conduit that extends between the upper substrate surface and the lower substrate surface, and at least one channel disposed on the upper substrate surface and in fluid communication with the conduit so that a vacuum, generated by a vacuum source to be provided to the system, is delivered to the poration area via the conduit and the at least one channel; ii) a first release liner having a top surface and an opposed bottom surface, wherein at least a portion of the bottom surface of the first release liner is connected to the upper substrate surface; and iii) a patch that is selectively removable from the top surface of the first release liner, the patch comprising: a) a backing layer having an upper surface and an opposed lower surface, and b) a reservoir mounted thereon a portion of the lower surface of the backing layer and configured for releaseably containing at least one permeant; wherein, in a connected position, at least a portion of the backing layer of the patch is releaseably mounted thereto the top surface of the first release liner in spaced registration with the poration area of the substrate.