Patent ID: 7399758

Claim:
A compound of formula I wherein: R 1 is CO 2 R 5 or CONR 6 R 7 ; R 2 is hydroxy, alkoxy, benzyloxy, NR 8 R 9 , or R 3 is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, or alkoxy; R 4 is C 5-7 cycloalkyl; R 5 is hydrogen or alkyl; R 6 is hydrogen, alkyl, cycloalkyl, alkoxy, or SO 2 R 10 ; R 7 is hydrogen, alkyl, or cycloalkyl; or NR 6 R 7 taken together is pyrrolidinyl, piperidinyl, piperazinyl, N-(alkyl)piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl; R 8 is hydrogen, alkyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, (CO 2 R 5 )alkyl, or (CON(R 5 )(R 5 ))alkyl; R 9 is hydrogen, alkyl, cycloalkyl, hydroxyalkyl, dihydroxyalkyl, alkoxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, (CO 2 R 5 )alkyl, or (CON(R 5 )(R 5 ))alkyl; or NR 8 R 9 taken together is pyrrolidinyl, piperidinyl, piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl, and is substituted with 0-2 substituents selected from halo, hydroxy, alkyl, hydroxyalkyl, alkoxyalkyl, amino, alkylamino, dialkylamino, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, pyrrolidinyl, piperidinyl, piperazinyl, N-(alkyl)piperazinyl, morpholinyl, thiomorpholinyl, and pyridinyl; and R 10 is alkyl, haloalkyl, cycloalkyl, phenyl, amino, alkylamino, dialkylamino, benzylamino, or (benzyl)(alkyl)amino; or R 10 is pyrrolidinyl, piperidinyl, piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl, and is substituted with 0-2 substituents selected from halo and alkyl; or a pharmaceutically acceptable salt thereof.