Patent ID: 8440652

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: A is aryl or 4-7-membered heterocycle; D is a 4-7-membered heterocycle; X is N or CH; Y 1 and Y 2 are each independently S, N or CH, provided that at least one of Y 1 and Y 2 is N or CH; each R 1 is independently R 1A , —(R 1B ) n SO p R 1C , —(R 1B ) n SO p N(R 1C ) 2 , —(R 1B ) n NR 1C SO p R 1C , —(R 1B ) n C(O)N(R 1C ) 2 , or —(R 1B ) n NR 1C C(O)R 1C , or optionally substituted C 1-12 hydrocarbyl or 2-12-membered heterocarbyl, which optional substitution is with one or more of R 1A ; each R 1A is independently amino, alkoxyl, carboxyl, cyano, halo, or hydroxyl; each R 1B is independently C 1-12 hydrocarbyl optionally substituted with one or more of amino, alkoxyl, carboxyl, cyano, halo, or hydroxyl; each R 1C is independently hydrogen or optionally substituted C 1-12 hydrocarbyl or 2-12-membered heterocarbyl, which optional substitution is with one or more of amino, alkoxyl, carboxyl, cyano, halo, or hydroxyl; each R 3A is independently amino, alkoxyl, carboxyl, cyano, halo, or hydroxyl; m is 0-3; n is 0 or 1; p is 0-2; and q is 0-2.