Patent ID: 6949543

Claim:
An amide derivative represented by the following general formula (I) or a salt thereof (symbols in the formula have the following meanings; R 1 and R 2 : the same or different from each other, and each represents —H, -lower alkyl, -lower alkenyl, -lower alkynyl, -cycloalkyl, -cycloalkenyl, —NRaRb, —NRc-NRaRb, —NRc-(nitrogen-containing saturated heterocyclic ring which may be substituted with lower alkyl), —NRc-C(═NH)—NRaRb, -(nitrogen-containing saturated heterocyclic ring which may be substituted with lower alkyl , -lower alkylene-NRaRb, -lower alkylene-(nitrogen-containing saturated heterocyclic ring which may be substituted with lower alkyl), —NRaCORb, —NRaCO—ORb, —NRaCO—NRbRc, —NRaCO-lower alkylene-NRbRc, —NRaCO-lower alkylene-(nitrogen-containing saturated heterocyclic ring which may be substituted with lower alkyl), —NRaSO 2 Rb, —NRaSO 2 —NRbRc, —NRaSO 2 -lower alkylene-NRbRc, —NRaSO 2 -lower alkylene-(nitrogen-containing saturated heterocyclic ring which may be substituted with lower alkyl), —CONRaRb, —SO 2 NRaRb, —COORa, —SO 2 Ra, —CONRa—ORb, —OCORa, —ORa, -halogen, —CORa, —NO 2 , —CN or -halogeno lower alkyl, Ra, Rb and Rc: the same or different from one another, and each represents —H, -lower alkyl, -lower alkenyl, -lower alkynyl, -cycloalkyl, -cycloalkenyl, -aryl, -5- or 6- membered monocyclic heteroaryl or -lower alkylene-aryl, A: -aryl which may have one or more substituents, -heteroaryl which may have one or more substituents, -saturated carbon ring-condensed aryl which may have one or ore substituents or -saturated heterocyclic ring-condensed aryl which may have one or more substituents, wherein the saturated carbon ring-condensed aryl and saturated heterocyclic ring-condensed aryl bind to the adjacent N atom via C atom of the aromatic ring, X: CO or SO 2 , R 3 : -alkyl which may have one or more substituents, -alkenyl which may have one or more substituents, -alkynyl which may have one or more substituents, -cycloalkyl which may have one or more substituents, -cycloalkenyl which may have one or more substituents, -aryl which may have one or more substituents, -hetero ring which may have one or more substituents or —NRaRb, or it may form a group represented by the following formula together with the adjacent group —N(-A)—X—, Y: O,S, a bond or CH 2 , R 3a : —H, -cycloalkyl which may have one or more substituents, -cycloalkenyl which may have one or more substituents, -aryl which may have one or more substituents or -hetero ring which may have one or more substituents, and A′ and B: the same or different from each other, and each represents benzene ring which may have one or more substituents).