Patent ID: 7012099

Claim:
A method for regulating the ORL1 receptor of the nociception/orphanin FQ ligand-ORL1 receptor system, comprising: administering a pharmaceutical composition comprising at least one substituted 4-amino-1-phenylbutan-2-ol compound of formula I wherein the radical A represents substituted or unsubstituted phenyl, the radicals R 1 and R 2 , form a (CH 2 ) 2-6 ring, which may also be substituted by phenyl, the radicals R 3 and R 4 , which may be identical or different, represent a C 1-6 -alkyl radical, the radicals R 5 , R 6 and R 7 , which may be identical or different, represent H, F, Cl, Br, I, CF 3 , OR 8 , SO 2 CF 3 , phenyl, CN, NO 2 or a C 1-6 -alkyl radical, the radical R 8 represents H, or a C 1-6 -alkyl radical, in the form of a racemate, an enantiomer, a diastereomer, base, or salt of a physiologically tolerable acid, and pharmaceuticallyu acceptable acceptable diluent or carrier to a human in need of regulation of the ORL1receptor of the nociceptin/orphanin FQ ligand-ORL1 receptor system for the treatment of anxiolysis.