Patent ID: 8258345

Claim:
A chiral compound of Formula III of at least about 50% enantiomeric purity wherein J is a linking chain of 2 members consisting of carbon atom members; the linking chain fused through adjacent linking chain members to a cyclohexyl ring optionally substituted with substituents independently selected from C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, halogen and nitro; such that the attached nitrogen atoms are held in a stereospecific orientation with respect to J and each other as depicted; each R 6 is independently selected from the group consisting of halogen; NO 2 ; cyano; C 2 -C 5 alkoxycarbonyl; N(C 1 -C 4 alkyl) 2 ; CON(C 1 -C 4 alkyl) 2 ; C 1 -C 4 alkoxy; C 2 -C 5 alkylcarbonyloxy; C 2 -C 5 alkoxycarbonyloxy; phenylcarbonyloxy optionally substituted with substituents independently selected from C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, halogen and nitro; tri(C 1 -C 4 alkyl)silyl; tri(C 1 -C 4 alkyl)siloxy; C 1 -C 4 alkyl optionally substituted with 1-3 phenyl rings; C 3 -C 6 cycloalkyl optionally substituted with C 1 -C 2 alkyl; adamantyl; a phenyl ring, or a 5- or 6-membered heteroaromatic ring, each ring optionally substituted with substituents independently selected from C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, halogen and nitro; and when two R 6 are attached to adjacent phenyl ring carbon atoms, said two R 6 may be taken together with the phenyl ring to form a naphthalene ring system optionally substituted on either ring of said naphthalene ring system with substituents independently selected from C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, halogen and nitro; and each n is independently an integer from 0 to 4; provided that (a) when J is a C 6 cycloalkyl ring connected via adjacent carbon atoms to the remainder of Formula III, then at least one n is an integer from 1 to 4; and (b) when J is a C 6 cycloalkyl ring connected via adjacent carbon atoms to the remainder of Formula III, on one phenyl ring n is 2 and (R 6 ) n is 3-t-butyl-5-methyl, then (R 6 ) n on the other phenyl ring is other than 3-t-butyl-5-methyl.