Patent ID: 8470821

Claim:
A compound having the chemical structure wherein: X is S; R 12 is optionally substituted amine, wherein the optional substituent for the amine, when present, is selected from the group consisting of lower alkyl, optionally substituted cycloalkyl, optionally substituted aryl, provided, however, that aryl is not substituted with sulfonamide, optionally substituted heteroaryl, acyl, and sulfonyl; R 13 is optionally substituted amine; R 14 is —C(Z)R 19 ; Z is S; and R 19 is selected from the group consisting of optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; or a pharmaceutically acceptable salt or stereoisomer thereof.