Patent ID: 8143425

Claim:
A compound according to Formula I: or a stereoisomer or pharmaceutically acceptable salt form thereof, wherein: R 1 and R 1a are independently selected from the group consisting of hydrogen, alkyl and arylalkyl; X a is selected from the group consisting of R 5 is selected from the group consisting of hydrogen and J 1 , R 5a is selected from the group consisting of hydrogen and aryl, R 5b is hydrogen; J 1 is —(CH 2 ) v OC(O)N(T 1a )T 1 ; T 1 and T 1a are independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, lower alkylthioalkyl, alkoxyalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloheteroalkyl and cycloalkyl, wherein alkyl, alkenyl, alkynyl, lower alkylthioalkyl, alkoxyalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloheteroalkyl and cycloalkyl of which may optionally be substituted with 0-3 substituents selected from the group consisting of halogen, hydroxyl, —NR 8d C(O)NR 8e R 8h , —C(O)NR 8d R 8e , —NR 8d C(O)R 8e , —CN, —N(R 8d )SO 2 R 8e , —OC(O)R 8d , —SO 2 NR 8d R 8e , —SOR 8h , —SO 2 R 8j , alkoxy, —COOH, cycloheteroalkyl and —C(O)OR 8k , or T 1 and T 1a may be taken together to form a 3-8 membered heteroaryl or heterocyclo ring; Y is X c is a direct bond; R 7 and R 7a are independently selected from the group consisting of H and alkyl, or R 7 and R 7a may be taken together to form a 3-7 membered ring; R 6 is hydrogen; R 8d R 8e , R 8h , R 8j and R 8k are independently selected from the group consisting of hydrogen, alkyl, alkenyl, cycloalkyl and aryl; X b is —NR 9 R 10 ; R 9 and R 10 are each hydrogen m and n are independently 0 to 3; and v is 0 to 5.