Patent ID: 8529927

Claim:
A method of treating a symptom of glaucoma, the method comprising the step of placing into the vitreous of an eye a melt extruded, monolithic, biodegradable intraocular implant comprising brimonidine tartrate associated with a biodegradable polymer, wherein the biodegradable polymer comprises a mixture of: a) an ester end-capped biodegradable poly(D,L-lactide) homopolymer having an inherent viscosity at 25° C. in 0.1% CHCl 3 of 0.25 to 0.35 dl/g; b) an ester end-capped biodegradable poly(D,L-lactide) homopolymer having an inherent viscosity at 25° C. in 0.1% CHCl 3 of 1.8 to 2.2 dl/g; and c) an acid end-capped biodegradable poly(D,L-lactide-co-glycolide) copolymer comprising 48-52 mol % D,L-lactide and 48-52 mol % glycolide and having an inherent viscosity at 25° C. in 0.1% CHCl 3 of 0.16 to 0.24 dl/g.