Patent ID: 8637692

Claim:
A process for preparing oxaliplatin (cis-oxalato-(trans-l-1,2-cyclohexanediamine)-platinum-II) of the structural formula I: comprising the following steps: a) reacting potassium tetrachloroplatinate (II) [K 2 PtCl 4 ] with trans-l-1,2-cyclohexanediamine to obtain the dichloro-[(trans-l-1,2-cyclohexandiamine-N,N′]-platinum(II) complex, b) reacting the dichloro-[(trans-l-1,2-cyclohexandiamine-N,N′]-platinum (II) complex with silver sulfate (Ag 2 SO 4 ) to obtain [(trans-l-1,2-cyclohexandiamine-N,N ′]-platinum(II)-diaquo sulphate and silver chloride (AgCl), c) reacting the [(trans-l-1,2-cyclohexandiamine-N,N′]-platinum(II)-diaquo-sulfate with barium oxalate (BaC 2 O 4 ) to yield oxaliplatin (cis-oxalato-(trans-l-1,2-cyclohexane-diamine)-platinum-II) and barium sulfate.