Patent ID: 7754751

Claim:
A method for preferentially inhibiting release of four or more pro-inflammatory cytokines over release of one or more anti-inflammatory cytokines in a subject, the method comprising administrating to the subject an effective amount of a compound of the following formula: wherein A is R or in which R is H, alkyl, aryl, cyclyl, heteroaryl, or heterocyclyl; Ar 1 is thienyl; Ar 2 and Ar 3 are independently phenyl, thienyl, furyl, or pyrrolyl; each of R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 , independently, is R′, nitro, halogen, —C(O)—OR′, —C(O)—SR′, —C(O)—NR′R″, —(CH 2 ) m OR′, —(CH 2 ) m SR′, —(CH 2 ) m NR′R″, —(CH 2 ) m CN, —(CH 2 ) m C(O)—OR′, or —(CH 2 ) m C(O)H, or R 1 and R 2 together, R 3 and R 4 together, or R 5 and R 6 together are —O(CH 2 ) m O—, in which each of R′ and R″, independently, is H, alkyl, cyclyl, aryl, heteroaryl, or heterocyclyl; and m is 0, 1, 2, 3, 4, 5, or 6; and n is 1, 2, or 3.