Patent ID: 8203004

Claim:
A compound of formula I: wherein V represents a bond, CH 2 or CH 2 CH 2 ; X represents CR 1a ; Y represents CO 2 H or tetrazole; Ar represents phenyl which optionally bears up to 3 substituents independently selected from hydrocarbon groups of up to 6 carbon atoms and (CH 2 ) m —Z where m is 0, 1 or 2 and Z represents halogen, N 3 , CN, CF 3 , OCF 3 or OR 4 ; R 1 represents Cl, Br, I, CN, or R 4 CO; R 1a represents H or C 1-4 alkyl; each R 2 is independently H or C 1-4 alkyl; R 3 is H, hydrocarbon containing up to 10 carbon atoms, benzyloxyC 1-4 alkyl or heterocyclylC 1-4 alkyl, any of which optionally bears up to 3 substitutents selected from halogen and CF 3 , or 1 substituent selected from C 1-4 alkoxy and C 1-4 alkylthio, wherein heterocyclyl refers to aromatic or nonaromatic rings of 5 or 6 atoms of which 1, 2 or 3 atoms are selected from N, O and S; R 4 represents H or a hydrocarbon group of up to 7 carbon atoms, optionally substituted with halogen, CN, CF 3 , OH, C 1-4 alkoxy or C 1-4 alkoxycarbonyl; R 5 represents R 4 that is other than H; p is 0, 1 or 2; and R 6 represents C 1-6 alkyl, C 2-6 alkenyl or phenyl, benzyl or heteroaryl, said phenyl, benzyl or heteroaryl optionally bearing up to 3 substituents selected from halogen, CN, CF 3 , OCF 3 , OR 4 , CO 2 R 4 , COR 4 , OCOR 5 and C 1-4 alkyl; or a pharmaceutically acceptable salt thereof.