Patent ID: 6903094

Claim:
A compound of the formula 1 wherein R 1 and R 2 are the same or different and each is hydrogen atom, lower alkyl optionally substituted by hydroxy, amino, lower alkylamino or di(lower)alkylamino; R 3 and R 4 are the same or different and each is hydrogen atom, halogen atom or lower alkyl; ring A is quinolinyl; ring B is phenyl; and X is a group of the formula wherein E is —O— or —S—; ring G is a heterocyclic group selected from the group consisting of pyridyl, pyrazinyl, pyrimidinyl, piperidinyl, piperazinyl, morpholinyl, and 1,3,5-triazinyl; R 5 is halogen atom, hydroxy, lower alkyl optionally substituted by any of halogen atom, hydroxy, lower alkanoyloxy and lower alkoxy optionally substituted by lower alkoxy, lower alkoxy optionally substituted by lower alkoxy, amino, lower alkylamino, di(lower)alkylamino, nitro, cyano, lower alkanoyl, lower alkanoyloxy, carboxy, lower alkoxycarbonyl, lower alkylsulfonyl or phenyl; t is 0 or an integer of 1 to 5, which indicates the number of substituents on the ring G, wherein when t is an integer of 2 to 5, each R 5 may be the same or different; m is 0 or an integer of 1 to 8; and n is 0 or an integer of 1 to 4, or a pharmaceutically acceptable salt thereof.