Patent ID: 7368567

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: m is from 0 to 3; n is from 1 to 3; p is from 0 to 3; Ar is optionally substituted aryl; X is —O—; R 1 and R 2 each independently is hydrogen, C 1-6 alkyl, or C 1-6 alkoxy-C 1-6 alkyl, or hydroxy-C 1-6 alkyl; or one of R 1 and R 2 is hydrogen or C 1-6 alkyl and the other is C 1-6 alkylcarbonyl, C 3-8 cycloalkyl, aryl-C 1-6 alkyl, hydroxy, or a five- or six-membered heteroaryl or heterocyclyl that contains one or two nitrogens; or R 1 and R 2 together with the nitrogen to which they are attached may form a three- to seven-membered ring that optionally contains an additional heteroatom selected from N, O and S; or R 1 and R 2 together with the nitrogen to which they are attached may form a guanidinyl group of the formula a carbamyl group of the formula or a urea group of the formula wherein each R 7 is independently hydrogen or C 1-6 alkyl; each R 3 is independently C 1-6 alkyl, hydroxy-C 1-6 alkyl or C 1-6 alkoxy-C 1-6 alkyl; or two of R 3 together with the atoms to which they are attached may form a C 4-6 carbocyclic ring; R 4 and R 5 each independently is hydrogen or C 1-6 alkyl; and each R 6 is independently halo, C 1-6 alkyl, halo-C 1-6 alkyl, or —SR c , where R c is hydrogen or C 1-6 alkyl.