Patent ID: 8013991

Claim:
A method comprising: generating a test Raman data set for an unknown sample; providing a reference Raman database containing a plurality of reference Raman data sets and a plurality of reference Raman difference data sets, said reference Raman difference data set being generated by configuring a processor to subtract a first reference Raman data set from a second reference Raman data set, said first reference Raman data set being associated with first known sample and associated with one or more of: a first known Gleason score and a first known clinical outcome, and a second reference Raman data set being associated with a second known sample and associated with one or more of: second known Gleason score and a second known clinical outcome; and providing a diagnosis of whether said unknown sample has a first Gleason score or a second Gleason scores by configuring a processor to compare said test Raman data set to said plurality of reference Raman difference data sets in said reference Raman database using a chemometric technique.