Patent ID: 7943607

Claim:
A compound of Formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 is selected from isopropyl, but-2-yl, 1,1,1-trifluoroprop-2-yl, 1,3-difluoroprop-2-yl, but-1-yn-3-yl, 1-hydroxyprop-2-yl, hydroxybut-3-yl, 1-hydroxybut-2-yl, tetrahydrofuranyl, tetrahydropyranyl, 1-methoxyprop-2-yl, 1-methoxybut-2-yl, 2-hydroxyprop-1-yl, 2-methoxyprop-1-yl, 2-hydroxybut-1-yl, 2-methoxybut-1-yl, 1-fluoromethoxyprop-2-yl, 1,1-difluoromethoxyprop-2-yl, and 1-trifluoromethoxyprop-2-yl; HET-1 is a 5- or 6-membered, C-linked heteroaryl ring containing a nitrogen atom in the 2-position and optionally 1 or 2 further ring heteroatoms independently selected from O, N, and S; which ring is optionally substituted on any nitrogen atom by a substituent selected from R 7 and/or on any available carbon atom by 1 or 2 substituents independently selected from R 6 ; HET-2 is a 5- to 7-membered heterocyclic ring fused to the benzene ring, containing 1, 2, or 3 ring heteroatoms independently selected from O, S, and N wherein any ring carbon or sulfur atom may optionally be oxidised and wherein HET-2 is optionally substituted on any nitrogen atom by a substituent selected from R 2 and/or on any available carbon atom by 1 or 2 substituents independently selected from R 3 ; R 2 is selected from (1-4C)alkyl, (3-6C)cycloalkyl, benzyl, (1-4C)alkylcarbonyl, (1-4C)alkylsulphonyl, hydroxy(1-4C)alkyl, and (1-4C)alkoxy(1-4C)alkyl; R 3 is selected from (1-4C)alkyl, (3-6C)cycloalkyl, (1-4C)alkoxy, hydroxy, fluoro, and chloro; R 4 is selected from hydrogen, fluoro, and chloro; R 6 is independently selected from (1-4C)alkyl, halo, hydroxy(1-4C)alkyl, (1-4C)alkoxy(1-4C)alkyl, (1-4C)alkylS(O) p (1-4C)alkyl, amino(1-4C)alkyl, (1-4C)alkylamino(1-4C)alkyl, di(1-4C)alkylamino(1-4C)alkyl, and HET-3; R 7 is independently selected from (1-4C)alkyl, hydroxy(1-4C)alkyl, (1-4C)alkoxy(1-4C)alkyl, (1-4C)alkylS(O) p (1-4C)alkyl, amino(1-4C)alkyl, (1-4C)alkylamino(1-4C)alkyl, di(1-4C)alkylamino(1-4C)alkyl, and HET-3; HET-3 is a 5- or 6-membered, C- or N-linked unsubstituted heteroaryl ring containing 1, 2, or 3 ring heteroatoms independently selected from O, N, and S; p is independently 0, 1, or 2.