Patent ID: 8044067

Claim:
A compound of the following formula (I): wherein, R 1 designates hydrogen; OH; CN; trifluoromethyl; NH 2 ; NHCN; NHCOCH 3 ; NHCOCH 2 CH 3 ; NHCHO; NHCOOCH 3 ; amino(C 1 -C 6 )alkyl; amino(C 1 -C 3 )dialkyl; (C 1 -C 6 )alkoxy; (C 1 -C 6 )alkyl; carbonyl-R 9 wherein R 9 designates hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy; (C 1 -C 6 ) alkyl-R 10 ; (C 1 -C 6 )alkoxy-R 10 ; amino(C 1 -C 6 )alkyl-R 10 and amino(C 1 -C 3 )dialkyl-R 10 whereby R 10 designates at least one OMe, OEt, OPr, OIsopropyl, OH, CN, NH 2 , ester groups with (C 1 -C 3 )alkyl, carbonate groups with (C 1 -C 3 )alkyl; R 2 designates (when R 3 , R 4 forms a carbonyl group) hydrogen; (C 1 -C 6 )alkyl; CH 2 CH 2 N(CH 3 ) 2 ; NH 2 ; NHCH 3 ; N(CH 3 ) 2 ; NHCN; NHCOCH 3 ; NHCOCH 2 CH 3 ; NHCHO; NHCOOCH 3 ; R 2 designates (when R 3 ═R 4 ═H) hydrogen; (C 1 -C 6 )alkyl; CN; CHO; COOCH 3 ; COOCH 2 CH 3 ; COCH 3 ; R 3 and R 4 designate hydrogen, or R 3 and R 4 taken together form a carbonyl group; R 6 designates hydrogen, or R 6 and R 7 taken together form a methylenedioxy group or an ethylenedioxy group; R 7 designates Me; (C 1 -C 4 )alkoxy; (C 1 -C 2 )alkoxy partly or fully fluorinated, OCF 3 ; trifluoromethyl; SMe; SEt or R 7 and R 8 taken together form a methylenedioxy group or an ethylenedioxy group; R 8 designates hydrogen; (C 1 -C 4 )alkyl; OH; (C 1 -C 4 )alkoxy; (C 1 -C 2 )alkoxy partly or fully fluorinated; OCF 3 ; trifluoromethyl; halogen or OX; R 3 ′ and R 5 ′ each independently designate OH; Me; Et; OMe; OMe partly or fully fluorinated; OCF 3 ; trifluoromethyl or halogen; U designates N or CR 2 ′, whereby R 2 ′ denotes hydrogen, (C 1 -C 4 )alkyl; (C 1 -C 4 )alkoxy; trifluoromethyl or halogen; V designates N or CR 4 ′, whereby R 4 ′ denotes hydrogen; (C 1 -C 6 )alkoxy; (C 1 -C 4 )alkoxy partly or fully fluorinated; (C 1 -C 6 )alkyl; OH; trifluoromethyl; halogen or OX; W designates N or CR 6 ′, whereby R 6 ′ denotes hydrogen; (C 1 -C 4 )alkyl; (C 1 -C 4 )alkoxy; trifluoromethyl or halogen; wherein OX designates a group capable of conferring a prodrug property, said group being selected among phosphate derivatives, ester derivatives, carbonate derivatives and/or linked poly(ethylene glycols) derivatives; or pharmaceutically acceptable salt thereof, provided that when: R 1 is H, R 2 and R 7 are Me, R 8 and R 4 ′ are H, R 5 ′ must be different from F or Cl; or R 1 , R 2 and R 7 are Me, R 8 and R 4 ′ are H, R 5 ′ must be different from F; or R 1 is H, R 2 and R 7 are Me, R 8 is H and R 4 ′ is F, R 5 ′ must be different from F.