Patent ID: 8597647

Claim:
An isolated humanized antibody, comprising: a heavy chain variable region (V H ), which comprises an amino acid sequence that is (i) identical to SEQ ID NO:1 or SEQ ID NO:3, or (ii) at least 90% identical to SEQ ID NO:1 or SEQ ID NO:3, and consisting of one or more mutations in one or more framework regions (FRs) in SEQ ID NO:1 or SEQ ID NO:3, and a light chain variable region (V L ), which comprises an amino acid sequence that is (i) identical to SEQ ID NO:5 or SEQ ID NO:7, or (ii) at least 90% identical to SEQ ID NO:5 or SEQ ID NO:7, and consisting of one or more mutations in one or more FRs in SEQ ID NO:5 or SEQ ID NO:7; wherein the antibody binds to human interleukin 20 (IL-20).