Patent ID: 8809379

Claim:
A method for treating pain, comprising administering to a subject in need thereof a therapeutically effective amount of at least one selective subtype modulator of alpha 2B and alpha 2C adrenergic receptors compound having the structure: wherein: X is S; and Z 1 -Z 6 are each independently C, N, O, or S, with the proviso that at least one of Z 1 -Z 6 is N; and n and m are each independently 1 to 5; and p is 1; and each R 1 and R 2 is independently H, lower alkyl, lower alkenyl, lower alkynyl, halide, hydroxy, alkoxy, trifluoromethyl, —N(R 6 ) 2 , —CN, —CO 2 R 6 , or —CH 2 OH; and R 3 , R 4 , R 5 , and R 6 are each independently H or lower alkyl.