Patent ID: 7897732

Claim:
An monoclonal antibody or antibody fragment thereof, that specifically binds to a heparin-binding growth factor (HBGF) polypeptide, wherein the amino acid sequence of the HBGF polypeptide is an amino acid sequence of the carboxy terminal of a human connective tissue growth factor (CTGF) protein from amino acid residue 247 to residue 349, wherein the amino terminal sequence of the HBGF polypeptide begins with SEQ ID NO: 1; or wherein the amino acid sequence of the HBGF polypeptide is an amino acid sequence of the carboxy terminal of a human CTGF protein from amino acid residue 248 to residue 349, wherein the amino terminal sequence of the HBGF polypeptide begins with SEQ ID NO: 2.