Patent ID: 7390903

Claim:
A compound of formula I wherein R 1 is hydrogen, C 1 -C 7 -alkyl, or C 3 -C 8 -cycloalkyl; R 2 is C 1 -C 7 -alkyl, CF 3 , C 3 -C 8 -cycloalkyl, optionally substituted aryl or optionally substituted heteroaryl having 5 to 9 ring atoms, wherein the substituents are selected from the group consisting of halo, C 1 -C 7 -alkoxy, C 1 -C 7 -alkylsulfonyl, and —C(O)O—C 1 -C 7 -alkyl; R 3 is —NR a R b ; optionally substituted heterocycloalkyl having 3 to 8 ring atoms, optionally substituted aryl, or optionally substituted heteroaryl having 5 to 9 ring atoms, wherein the substituents are selected from the group consisting of halo, C 1 -C 7 -alkoxy, C 1 -C 7 -alkylsulfonyl, and —C(O)O—C 1 -C 7 -alkyl; R 4 is hydrogen, or C 1 -C 7 -alkyl; and R 5 is hydrogen, halo, C 1 -C 7 -alkyl, optionally substituted aryl or optionally substituted heteroaryl having 5 to 9 ring atoms, wherein the substituents are selected from the group consisting of halo, C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy, and —C(O)O—C 1 -C 7 -alkyl; or R 5 together with R 4 forms a ring selected from the group consisting of C 5 -C 7 -cycloalkyl, phenyl, pyridinyl, and pyrimidinyl which are optionally substituted or by one or more halo, cyano, C 1 -C 7 -alkylsulfonyl, C 1 -C 7 -alkyl, C 1 -C 7 -haloalkyl, C 1 -C 7 -alkoxy, C 1 -C 7 -haloalkoxy, or —C(O)O—C 1 -C 7 -alkyl; or heterocycloalkyl having 5 to 7 rings atoms, optionally substituted by one or more cyano, C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy, or C(O)O—C 1 -C 7 alkyl; R a and R b are each independently C 1 -C 7 -alkyl, or R a and R b , together with the nitrogen atom to which they are attached, form a unsubstituted piperidine; or a pharmaceutically acceptable salt thereof.