Patent ID: 7939657

Claim:
A compound of the formula or a pharmaceutically acceptable salt thereof wherein n is 1, 2, or 3; R 1 is heteroaryl(C 1 -C 6 )alkyl wherein the cyclic portion is substituted with 1, 2, 3, 4, or 5 groups that are independently halogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 4 haloalkyl, C 1 -C 4 haloalkoxy, aryl, arylalkyl, aryloxy, heteroaryl, —SO 2 -aryl, —S(O) x —R 25 , —(C 1 -C 4 alkyl)-S(O) x —R 25 , CN, C 1 -C 6 thioalkoxy, C 1 -C 6 alkoxycarbonyl, —NR′R″, —C(O)—NR′R″, or heterocycloalkyl, wherein the above aryl groups are optionally substituted with 1, 2, 3, or 4 groups that are independently halogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 4 haloalkyl, or C 1 -C 4 haloalkoxy; wherein the above heteroaryl and heterocycloalkyl groups are optionally substituted with 1, 2, or 3 groups that are independently halogen, CF 3 , (C 1 -C 4 )alkyl, C 1 -C 6 thioalkoxy, OH, C 1 -C 4 hydroxyalkyl, or C 1 -C 4 alkoxy; or R 1 is heterocycloalkyl (C 1 -C 6 alkyl) wherein the heterocycloalkyl portion contains from 4-7 members and is optionally substituted with 1, 2, 3, 4, or 5 groups that are independently halogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 4 haloalkyl, C 1 -C 4 haloalkoxy, aryl, arylalkyl, aryloxy, heteroaryl, —SO 2 -aryl, —S(O) x —R 25 , —(C 1 -C 4 alkyl)-S(O) x —R 25 , CN, C 1 -C 6 thioalkoxy, C 1 -C 6 alkoxycarbonyl, —NR′R″, —C(O)—NR′R″, heterocycloalkyl; each x is independently 0, 1, or 2; R 25 is C 1 -C 6 alkyl, OH, NR 26 R 27 ; R 26 and R 27 are independently H, C 1 -C 6 alkyl, phenyl(C 1 -C 4 alkyl), aryl, or heteroaryl; or R 26 , R 27 and the nitrogen to which they are attached form a heterocycloalkyl ring; wherein R′ at each occurrence is independently H, C 1 -C 6 alkyl, aryl, aryl(C 1 -C 4 )alkyl, C 1 -C 6 alkanoyl, C 3 -C 6 cycloalkyl, aryl(C 1 -C 6 )alkanoyl, heterocycloalkyl, heteroaryl(C 1 -C 4 )alkyl, —SO 2 -alkyl, —SO 2 -aryl, —SO 2 -heteroaryl, heterocycloalkyl(C 1 -C 6 )alkanoyl, or heteroaryl(C 1 -C 6 )alkanoyl, wherein the alkyl portion of the alkyl and alkanoyl groups are optionally substituted with halogen or C 1 -C 6 alkoxy, wherein the aryl, and heteroaryl groups are optionally substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, halogen, C 1 -C 4 haloalkyl, C 1 -C 4 haloalkoxy; wherein R″ at each occurrence is independently H, or C 1 -C 6 alkyl, wherein the alkyl group is optionally substituted with halogen; and R 2 is H, C 1 -C 6 alkyl, or phenyl(C 1 -C 4 )alkyl.