Patent ID: 8575208

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein R 1 is an optionally substituted aryl: R 2 and R 3 together form an oxo group; A is —O—, or —CH 2 —; R 4 is —NH—CHR 4x —C(O)—(CO)—N(R 4z )R 4W ; R 4W is hydrogen, optionally substituted aliphatic, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocycloaliphatic, or optionally substituted cycloaliphatic; R 4X is hydrogen, optionally substituted aliphatic, optionally substituted heteroaryl, optionally substituted phenyl, optionally substituted cycloaliphatic, or optionally substituted heterocycloaliphatic; R 4Z is hydrogen, optionally substituted aliphatic, optionally substituted cycloaliphatic, optionally substituted heterocycloaliphatic, optionally substituted aryl, or optionally substituted heteroaryl; R 5 is R 13 is T is —C(O)—, and R is