Patent ID: 6995159

Claim:
A compound of Formula (IC) wherein X and Y are CR and Z is N, or X is N and Y and Z are CR, where R for each occurrence is hydrogen, halogen, (C 1 –C 4 )alkyl, amino, or (C 1 –C 4 )alkylamino; W is oxy, thio, amino, (C 1 –C 4 )alkylamino, or acetylamino; Q is a heteroaryl group selected from the group consisting of pyridin-2-yl, pyridin-3-yl, furan-3-yl, furan-2-yl, thiophen-2-yl, thiophen-3-yl, thiazol-2-yl, pyrrol-2-yl, pyrrol-3-yl, pyrazol-3-yl, quinolin-2-yl, quinolin-3-yl, isoquinolin-3-yl, benzofuran-2-yl, benzofuran-3-yl, isobenzofuran-3-yl, benzothiophen-2-yl, benzothiophen-3-yl, indol-2-yl, indol-3-yl, 2H-imidazol-2-yl, oxazol-2-yl, isoxazol-3-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-triazol-3-yl, and 1,2,4-oxathiazol-3-yl, where said heteroaryl group is optionally substituted with one to three substituents independently selected from halo, (C 1 –C 4 )alkyl or (C 1 –C 4 )alkyoxy; R 2a and R 2b are each independently hydrogen, (C 1 –C 4 )alkyl, or partially or fully saturated (C 3 –C 6 )cycloalkyl; R 3a and R 3b are each independently hydrogen, (C 1 –C 4 )alkyl, or (C 1 –C 4 )alkyl substituted with hydroxy, fluoro, or (C 1 –C 4 )alkoxy; R 4 is hydrogen, hydroxy, (C 1 –C 4 )alkyl, (C 1 –C 4 )alkyl substituted with hydroxy or cyano, (C 1 –C 4 )alkylcarbonyl, (C 1 –C 4 )alkoxy, (C 1 –C 4 )alkoxy-carbonyl, or (C 3 –C 4 )alkenyl; a nitrogen oxide thereof, an ester or amide prodrug of said compound or said nitrogen oxide; a pharmaceutically acceptable salt of said compound, said nitrogen oxide, or said prodrug, or a pharmaceutically acceptable solvate or hydrate of said compound, said nitrogen oxide, said prodrug, or said salt.