Patent ID: 8486402

Claim:
An isolated monoclonal antibody or fragment thereof which specifically binds to a CD98 epitope bound by an antibody or fragment thereof that: i. has any pair of sequences of (a) SEQ ID NOs: 41 and 47, (b) SEQ ID NOs: 43 and 47, (c) SEQ ID NOs: 43 and 77, (d) SEQ ID NOs: 43 and 79, (e) SEQ ID NOs: 43 and 81, (f) SEQ ID NOs: 43 and 83; and (g) SEQ ID NOs: 29 and 31, or ii. is produced by the cell line having a plasmid deposited under Accession Number FERM BP-10551 or a plasmid deposited under Accession Number FERM BP-10552, or iii. has the amino acid sequences of a variable region encoded by a BglII-BsiWI fragment and a SalI-NheI fragment obtained from a plasmid vector K3/pCR4 deposited under Accession Number FERM BP-10552.