Patent ID: 8753283

Claim:
A device for remote ischemic preconditioning, the device comprising: a cuff sized to retract about a limb of a subject, a controller connected to said cuff, said controller configured to inflate and deflate said cuff according to a remote ischemic preconditioning treatment protocol, said treatment protocol includes at least two sequentially performed treatment cycles, each of said treatment cycles comprising: inflating said cuff to a cuff pressure at or above a limb occlusion pressure of the subject, maintaining said cuff pressure at or above said limb occlusion pressure for a period of at least about one minute, and deflating said cuff for at least about one minute to restore blood flow in said limb, wherein during maintaining said cuff pressure at or above said limb occlusion pressure, said controller is further configured to vary said cuff pressure at least once after a predetermined period of time during at least one of said treatment cycles.