Patent ID: 8768629

Claim:
A method of identifying one or more candidate treatment for a subject in need of treatment for a cancer, comprising: (a) performing an immunohistochemistry (IHC) analysis on a sample from the subject on at least: TOP1, TYMS, MGMT, PTEN, ERBB2, and SPARC; (b) performing a microarray analysis on the sample on at least: TOP1, TYMS, MGMT, PTEN, ERBB2, and SPARC; (c) performing a fluorescent in-situ hybridization (FISH) analysis on the sample on ERBB2; (d) performing DNA sequencing analysis on the sample on PIK3CA, KRAS, and BRAF; and (e) using a computer to access a rules database comprising the biomarker-drug association rules presented in Table 2 and perform all rules in the database for each gene or gene product analyzed in steps a)-d); and (f) producing a computer generated report based on the rules s performed in step e), wherein the report identifies the one or more candidate treatment.