Patent ID: 8883785

Claim:
At least one chemical entity chosen from compounds of Formula I and pharmaceutically acceptable salts thereof wherein: R 1 is phenyl substituted with one, two, or three groups chosen from halo, optionally substituted lower alkyl, optionally substituted lower alkoxy, and hydroxyl; R 2 is chosen from [1,2,4]oxadiazol-5-yl, [1,2,4]oxadiazol-3-yl, 4H-[1,2,4]oxadiazol-5-one-3-yl, 4H-[1,2,4]oxadiazole-5-thione-3-yl, [1,2,4]triazol-1-yl, 1H-tetrazol-5-yl, 2H-tetrazol-5-yl, tetrazol-1-yl, 2,4-dihydro-[1,2,4]triazol-3-one-5-yl, 4H-[1,2,4]triazol-3-yl, each of which is optionally substituted; R 3 is chosen from hydrogen and optionally substituted lower alkyl and R 4 is chosen from hydrogen, halo, and optionally substituted lower alkyl.