Patent ID: 6943179

Claim:
A compound of the formula I wherein R is H, Hal or CN, R 1 is H, A or (CH 2 ) n -Ar, R 2 is H or Hal, R 3 is phenyl which is unsubstituted or monosubstituted by SO 2 A, SO 2 NHA or SO 2 NH 2 , or Het, X is (CH 2 ) n , Y is absent, Z is CH or N, Ar is phenyl which is unsubstituted or monosubstituted or disubstituted by Hal, phenyl, A, OH, OA, NH 2 , NHA, NA 2 , NO 2 , CN, COOH, COOA, CONH 2 , CONHA, CONA 2 , NHCHO, NACHO, NHCOA, NACOA, NHSO 2 A, NASO 2 A, CHO, COA, SO 2 NH 2 , SO 2 NHA or SO 2 NA 2 , Het is a monocyclic saturated, unsaturated or aromatic heterocyclic radical having from 1 to 4 N, O and/or S atoms, which may be unsubstituted, monosubstituted or disubstituted by carbonyl oxygen, Hal, A, OH, OA, NH 2 , NHA, NA 2 , NO 2 , CN, COOH, COOA, CONH 2 , CONHA, CONA 2 , NHCHO, NACHO, NHCOA, NACOA, NHSO 2 A, NASO 2 A, CHO, COA, SO 2 NH 2 , SO 2 NHA or SO 2 NA 2 , A is unbranched or branched alkyl having 1-6 carbon atoms, in which one or two CH 2 groups may be replaced by O or S atoms and/or by —CH═CH— groups and/or in addition 1-7 H atoms may be replaced by F, Hal is F, Cl, Br or I, n is 0, 1 or 2, or a pharmaceutically acceptable salt solvate, stereoisomer or a mixture thereof.