Patent ID: 8283157

Claim:
An electrolytic system for increasing nanopore and molecule interactions comprising: an analyte chamber having a length L adapted to contain a sample solution, the analyte chamber including an access port for introduction of fluids into the analyte chamber; at least one nanopore formed in the analyte chamber within an interaction region, the at least one nanopore includes first and second opposing sides; and first and second electrodes, both arranged on the first side of the at least one nanopore within the analyte chamber, adapted to create an electric field along the length L of the analyte chamber to drive molecules of interest toward the interaction region; third and fourth electrodes located on the first and second opposing sides of the nanopore respectively, wherein actuation of the first and second electrodes is adapted to increase an arrival rate of molecules of interest to the first side of the nanopore wherein the third and fourth electrodes are adapted to apply an electric field across the nanopore to drive one of the molecules of interest into the nanopore.