Patent ID: 8440234

Claim:
A standardized bee venom preparation suitable for administration by injection prepared by a process comprising (a) dissolving pure dried bee venom crystals in a liquid carrier to obtain a bee venom preparation in a concentration of between about 0.1 milligram (mg) to about 10.0 mg by weight of bee venom per milliliter (mL) of said bee venom preparation, (b) purifying said bee venom preparation through a filter to obtain a standardized bee venom preparation, wherein said standardized bee venom preparation comprises between about 0.1 mg to about 1.0 mg of pure melittin and about 400 microgram (mcg) to about 4,500 mcg of total protein per mL of said standardized bee venom preparation, wherein said standardized bee venom preparation exhibits 40 to 100 honey bee hyaluronidase units per mL (HHU/mL) of hyaluronidase activity when diluted to 100 mcg/mL and is capable of inhibiting gelatin induced aggregation of erythrocytes of 3-5 millimeter per hour (mm/H).