Patent ID: 7625995

Claim:
An activated compound having a formula: where an activated moiety is attached to the hydroxyl group and wherein the activated moiety is selected from the group consisting of chloroformate, NHS carbonate, DSC para-nitrochloroformate, p-nitrochloroformate, phosgene and paranitrophenyl carbonate, and R 1 is selected from the group consisting of H, alkyl; m is 1-5; q is 0-4; Olig is an oligomer having a formula: -L-O-X-PAG.[R 2 ] n where: L is an optional linker moiety selected from the group consisting of —CH 2 —, —C(O)X′, —C(O)NH—, —C(O)NHX′—, and wherein X′ is alkyl 1-6 ; X is an alkyl or is not present; PAG is a linear or branched polyalkylene glycol moiety; R 2 is an H or an alkyl; and n is 1 if PAG is a linear polyalkylene glycol moiety or equal to the maximum number of polyalkylene glycol moieties if the PAG is branched.