Patent ID: 7666981

Claim:
A method of inhibiting prostasin, the method comprising administering to a subject in need thereof a serine protease inhibitor having a reactive center loop consisting of a peptide of the formula P 15 P 14 P 13 P 12 P 11 P 10 P 9 P 8 P 7 P 6 P 5 P 4 P 3 P 2 P 1 wherein P 1 to P 15 are amino acid residues, wherein the tetrapeptide subsequence P 4 -P 1 consists of SEQ ID NO:1, and wherein the subsequence P 15 P 14 P 13 P 12 P 11 P 10 P 9 P 8 P 7 P 6 P 5 consists of SEQ ID NO:2.