Patent ID: 7271258

Claim:
A nucleoside monomer having the structure of formula (II) or formula (X) wherein: B is a purine or pyrimidine base; R is hydrido or hydroxyl; R 1 is COOR 3 , wherein R 3 is substituted or unsubstituted hydrocarbyl, wherein the hydrocarbyl is selected from the group consisting of alkyl, aryl, aralkyl, alkaryl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl or cycloalkynyl, wherein the substitution is on one or more carbon atoms and the substitution is by a group selected from a cyano group, a nitro group, and a halo group; and R 2 has the structure (III) wherein X is NQ 1 Q 2 in which Q 1 and Q 2 are independently selected from the group consisting of alkyl, aryl, aralkyl, alkaryl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl or cycloalkynyl, or wherein Q 1 and Q 2 are linked to form a mono- or polyheterocyclic ring, wherein Q 1 and Q 2 have 1 to 3 heteroatoms and 2 to 12 carbon atoms, wherein the polyheterocyclic ring includes 2 to 3 rings, and Y is hydrido or hydrocarbyl.