Patent ID: 7074617

Claim:
A method of producing an insect synthetic antigen presenting cell comprising: a) transforming the cell with an expressible MHC class II Î±-chain gene operably linked to a first promoter in a vector capable of expressing an MHC class II Î±-chain; b) transforming the cell with an expressible MHC class II Î²-chain gene operably linked to a second promoter in a vector capable of expressing an MHC class II Î²-chain; and c) transforming the cell with a first expressible accessory molecule gene operably linked to a third promoter in a vector capable of expressing an accessory molecule, wherein the accessory molecule is selected from the group consisting of: a B7.1, a B7.2, an ICAM-1, an ICAM-2, an ICAM-3, an LFA-3, a Fas ligand, and a CD70.