Patent ID: 7956996

Claim:
A method comprising: providing a group of known breast samples, each known breast sample having an associated known breast disease state, said known breast disease state including an invasive ductal carcinoma disease state or an invasive lobal carcinoma disease state; obtaining a Raman data set from each known breast sample; analyzing each Raman data set to identify an invasive ductal carcinoma reference Raman data set or invasive lobular carcinoma reference Raman data set depending on whether respective known breast sample is said invasive ductal carcinoma sample or said invasive lobular carcinoma sample; generating a first database containing all invasive ductal carcinoma reference Raman data sets generating a second database containing all invasive lobular carcinoma reference Raman data sets; obtaining a test Raman data set of a test breast sample having an unknown breast disease state; and providing a diagnostic of whether said test breast sample has an invasive ductal carcinoma disease state or a invasive lobular carcinoma disease state by comparing said test Raman data set against reference Raman data sets in said first reference Raman and said second reference Raman databases using a chemometric technique.