Patent ID: 8148572

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: in which: A is selected from hydrogen, halogen, CN, OR 3 , phenyl, 6 member heteroaromatic ring containing N, or C 1-6 alkyl, the latter group being optionally substituted by halogen atoms; D is hydrogen, halogen or C 1-6 alkyl, the latter group being optionally substituted by one or more halogen atoms; E is O; V is C(H); W is a carbon atom substituted by hydrogen, halogen, CN, or C 1-3 alkyl (the latter group being optionally substituted by halogen atoms); X is a carbon atom substituted by hydrogen, halogen, CN, or C 1-3 alkyl (the latter group being optionally substituted by halogen atoms); Y is selected from hydrogen, CN, halogen or C 1-6 alkyl (the latter being optionally substituted by one or more halogen atoms); Z is selected from SO 2 morpholine, CONR 4 R 5 , COR 6 or SO 2 R 9 ; R 1 and R 2 independently represent a hydrogen atom, halogen or a C 1-6 alkyl group; R 3 is hydrogen or C 1-6 alkyl (optionally substituted by halogen or NR 4 R 5 ) or; R 4 and R 5 independently represent hydrogen or C 1-6 alkyl R 6 represents plenyl or pyrrolidine; and R 9 represents phenyl, benzyl, methylpyridine or C 1-6 alkyl, optionally substituted by one or more halogen atoms; provided that: A and D cannot both be hydrogen; A cannot be aryl substituted in the para-position by —S(O) n —, where n is 0, 1 or 2; and when V, W and X are all carbon then all of the substituents on the phenyl ring (V, W, X, Y and Z) cannot be hydrogen.