Patent ID: 8883429

Claim:
A method of assessing lymphocytic choriomeningitis virus (LCMV) infection status or activity in a subject, the method comprising: selecting a subject for assessment, wherein the subject has been exposed to LCMV and/or is at risk of increased LCMV activity; obtaining a sample from the subject: contacting the sample with a composition for detecting LCMV, wherein the composition comprises at least one isolated monoclonal antibody or antibody fragment thereof, comprising a heavy chain variable region (V H ) of monoclonal antibody M87 comprising the amino acid sequence of SEQ ID NO: 74, wherein the V H region comprises a V H CDR1 comprising SEQ ID NO: 76; a V H CDR2 comprising SEQ ID NO: 77; and a V H CDR3 comprising SEQ ID NO: 78, and wherein the antibody or fragment binds specifically to LCMV NP; and determining whether the composition for detecting LCMV is associated with a marker of LCMV from the sample, wherein detection of an association indicates that the subject is infected with and/or has active LCMV.