Patent ID: 8536158

Claim:
A pharmaceutical composition comprising: (a) a pharmaceutical excipient or carrier; (b) a compound of formula (II) wherein W is chloro or fluoro; R 1 is phenyl, optionally substituted with one or more substituents, selected from halo; and R 4 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkyl substituted with aryl, aryl, (CH 2 ) m OC(═O)C 1 -C 6 alkyl, ((CH 2 ) m O) n CH 2 CH 2 X, (CH 2 ) m N(R 5 ) 2 , or CH((CH 2 )O(C═O)R 6 ) 2 ; m is 1 or 2; n is 1-4; X is OR 5 or N(R 5 ) 2 ; R 5 is hydrogen or methyl; and R 6 is C 1 -C 18 alkyl; or a pharmaceutically acceptable salt thereof; and (c) one or more additional active agents useful in the treatment of diseases and conditions mediated by PGD 2 or other agonists at the CRTH2 receptor.