Patent ID: 6982246

Claim:
A compound capable of inhibiting activation of cytotoxic T lymphocytes and/or natural killer cells, said compound consisting of an oligopeptide of at least 8 amino acids, wherein said oligopeptide is within the amino acid sequence: aa 70 aa 71 Q T aa 74 R aa 76 aa 77 L aa 79 aa 80 aa 81 aa 82 aa 83 Y Y W aa 87 aa 88 aa 89 aa 90 aa 91 (SEQ ID NO: 57), wherein: aa 70 is Q, H, S, N or K; aa 71 is an aliphatic neutral amino acid; aa 74 is D, Y or H; aa 76 is E or V; aa 77 is D, S or N; aa 79 is R or G; aa 80 is T, I, N or an aromatic amino acid; aa 81 is an aliphatic non-polar amino acid; aa 82 is R, L or an aromatic amino acid; aa 83 is G or R; aa 87 is any amino acid; aa 88 is an aromatic amino acid or aliphatic amino acid of from 5 to 6 carbon atoms; aa 89 is any amino acid; aa 90 is any amino acid; and aa 91 is any amino acid; and wherein said oligopeptide includes the triad YYW (SEQ ID NO:1) of said sequence.