Patent ID: 7541347

Claim:
A method of administering an oral dosage form for the treatment of acne comprising: (i) administering to a patient the oral dosage form, the oral dosage form comprising: (a) an intragranular blend of: 90 mg of minocycline hydrochloride; 108 mg of the matrix-forming polymer hydroxpropyl methylcellulose, wherein the matrix-forming polymer hydroxypropyl methylcellulose is a slow dissolving carrier; and 152 mg of an intragranular lactose; and (b) 41 mg of extragranular lactose monohydrate, wherein the extragranular lactose monohydrate is a fast dissolving carrier, a portion of which completely or partially encapsulates or coats the intragranular blend; (c) 3.0 mg of silicon oxide; and (d) 6.0 mg of magnesium stearate, wherein the dosage form has a total weight of 400 mg; wherein the dosage form provides a patient with 0.75 mg/kg to 1.5 mg/kg of the minocycline hydrochloride in a slow, continuous fashion, without an initial load dose, that effectively treats acne of the patient by the once daily administration of the dosage form, and (ii) providing information to the patient, which information comprises results of the performed clinical trials including a comparison of the oral dosage form to placebo with respect to an aspect of at least one adverse effect.