Patent ID: 8865130

Claim:
A therapeutic and/or diagnostic agent, wherein the therapeutic and/or diagnostic agent has the following structural formula: wherein: R 1 =C 1 to C 6 alkyl, C 1 to C 6 branched alkyl, C 4 to C 8 cycloakyl, C 4 to C 8 aryl, C 4 to C 8 aryl-substituted C 1 to C 6 alkyl, C 1 to C 6 alkoxy, C 1 to C 6 branched alkoxy, C 4 to C 8 aryloxy, or halo-substituted versions thereof, or R 1 is halo where halo is chloro, fluoro, bromo, or iodo; R 2 =C 1 to C 6 alkyl, C 4 to C 8 aroyl, C 4 to C 8 aryl, C 4 to C 8 heterocyclic alkyl or aryl with O, N or S in the ring, C 4 to C 8 aryl-substituted C 1 to C 6 alkyl, alkyl-substituted or aryl-substituted C 4 to C 8 heterocyclic alkyl or aryl with O, N or S in the ring, alkyl-substituted C 4 to C 8 aroyl, or alkyl-substituted C 4 to C 8 aryl, or halo-substituted versions thereof or R 1 is halo where halo is chloro, bromo, or iodo; X is an active agent selected from the group consisting of a chemotherapeutic agent and a detectable agent, wherein the detectable agent is selected from the group consisting of a fluorophore, a cyanine dye, and a near infrared (NIR) dye; and further wherein the fluorophore is selected from the group consisting of dansyl chloride, dabsyl chloride, nitrobenzodiazolamine (NBD), fluorescein and derivatives thereof, rhodamine and derivatives thereof, Nile Blue, an Alexa Fluor and derivatives thereof, and combinations thereof; A is a tether; B is O or —NH; and n is 0-4.