Patent ID: 8420685

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R 1 is phenyl fused with a non-aromatic cyclic ring of 5 or 6 members wherein said cyclic ring optionally contains up to two oxygen atoms, or R 1 is phenyl substituted by one or more substituents selected from the group consisting of halo, OH and —O—C 1-6 alkyl; R 2 is H, OH, —O—C 1-6 alkyl, —S—C 1-6 alkyl, C 1-6 alkyl, C 1-6 haloalkyl, NH 2 , or halo; R 3 is H, C 1-6 alkyl, C 3-7 cycloalkyl, —(CH 2 ) p —NO 2 , —(CH 2 ) p —NR 4 R 5 , —(CH 2 ) p —CHO, —(CH 2 ) p —CONHOH, —(CH 2 ) p —CN, —(CH 2 ) p —CO 2 H, —(CH 2 ) p —CO 2 R 4 , —(CH 2 ) p —CONR 4 R 5 , —(CH 2 ) p —tetrazole, —(CH 2 ) p —COR 4 , —(CH 2 ) q —(OR 6 ) 2 , —(CH 2 ) p —OR 4 , —(CH 2 ) p —CH═CH—CN, —(CH 2 ) p —CH═CH—CO 2 H, —(CH 2 ) p —CH═CH—CO 2 R 4 , —(CH 2 ) p —CH═CH—CONR 4 R 5 , —(CH 2 ) p —NHCOR 4 , —(CH 2 ) p —NHCO 2 R 4 , —(CH 2 ) p —CONHSO 2 R 4 , —(CH 2 ) p —NHSO 2 R 4 or —(CH 2 ) p —CH═CH-tetrazole; R 4 and R 5 are independently H or C 1-6 alkyl; R 6 is C 1-6 alkyl; p is 0, 1, 2, 3, or 4; q is 1, 2, 3, or 4; X is C 1-10 alkylene; one of A 1 and A 2 is N and the other is NR 7 ; and R 7 is H, or C 1-6 alkyl.