Patent ID: 8268843

Claim:
A compound of formula (I) wherein: R represents H, CH 3 , or a heterocycle selected from the group consisting of pyridinyl, pyrazinyl, pyrimidinyl, and pyridazinyl wherein the heterocycle may be optionally substituted with one or more groups selected from halo, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, haloalkyl, haloalkoxy, NO 2 , CN, lower alkoxycarbonyl, and lower alkyl-SO q , when q is an integer from 0 to 2; Z represents a C—C single bond, CH 2 , NH, O, S, —CH 2 O—, or —OCH 2 —; m is 4; R 1 are independently H, halo, lower alkyl, lower alkenyl, lower alkynyl, hydroxy, lower alkoxy, haloalkyl, haloalkoxy, NO 2 , CN, lower alkoxycarbonyl, mercapto, or lower alkylthio; Y is a C—C single bond, C(R 7 n )O or C(R 7 n ); n is 2; R 2 are independently H or lower alkyl; R 7 are independently H or lower alkyl; X is NR 3 or O, where R 3 is selected from H, lower alkyl, lower alkyl-carbonyl, lower alkoxycarbonyl, hydroxy, lower alkoxy, lower alkyl-SO q , phenyl-SO q or substituted phenyl-SO q when q is an integer from 0 to 2; and R 4 is H or F; with the proviso that when Y is C(R 7 n ), R 2 n and one of R 1 may be taken together to form a compound of formula (II)