Patent ID: 7166603

Claim:
A compound having the formula, or an enantiomer, diastereomer, or salt, thereof, wherein A is a group of formula X is oxygen or sulfur; J is n-propylene; R 1 is alkyl optionally substituted with Z 1b , Z 2b and/or one or more Z 3b ; R 2 is CO 2 R 5 ; R 3 is —N(R 6 )C(O)R 7 ; R 4 is hydrogen or alkyl, R 5 is alkyl; R 6 is hydrogen or alkyl; R 7 is selected from Z 1 and 1b, and 1g , Z 2b , and Z 3b are optional substituents independently selected from (1) R 10 , where R 10 is (i) alkyl, (hydroxy)alkyl, (alkoxy)alkyl, alkenyl, alkynyl, cycloalkyl, (cycloalkyl)alkyl, cycloalkenyl, (cycloalkenyl)alkyl, aryl, (aryl)alkyl, heterocyclo, (heterocylco)alkyl, heteroaryl, or (heteroaryl)alkyl; (ii) a group (i) which is itself substituted by one or more of the same or different groups (i); or (iii) a group (i) or (ii) which is independently substituted by one or more of the following groups (2) to (13) of the definition of Z 1 , (2) —OH or —OR 10 , (3) —SH or —SR 10 , (4) —C(O) t H, —C(O) t R 10 , or —O—C(O)R 10 , where t is 1 or 2, (5) —SO 3 H, —S(O) t R 10 , or S(O) t N(R 11 )R 10 , (6) halo, (7) cyano, (8) nitro, (9) —U 1 —N R 12 R 13 , (10) —U 1 —N(R 11 )—U 2 —N R 12 R 13 , (11) —U 1 —N(R 14 )—U 2 —R 10 , (12) —U 1 —N(R 14 )—U 2 —H, (13) oxo; U 1 and U 2 are each independently (1) a single bond, (2) —U 3 —S(O) t —U 4 —, (3) —U 3 —C(O)—U 4 —, (4) —U 3 —C(S)—U 4 —, (5) —U 3 —O—U 4 —, (6) —U 3 —S—U 4 —, (7) —U 3 —O—C(O)—U 4 —, (8) —U 3 —C(O)—O—U 4 —, (9) —U 3 —C(═NR 15 )—U 4 —, or (10) —U 3 —C(O)—C(O)—U 4 ; R 11 , R 12 , R 13 , R 14 and R 15 (1) are each independently hydrogen or a group provided in the definition of Z 1 ; or (2) R 12 and R 13 may together be alkylene or alkenylene, completing a 3- to 8-membered saturated or unsaturated ring together with the atoms to which they are attached, which ring is unsubstituted or substituted with one or more groups listed in the definition of Z 1 , or (3) R 12 or R 13 , together with R 11 , may be alkylene or alkenylene completing a 3- to 8-membered saturated or unsaturated ring together with the nitrogen atoms to which they are attached, which ring is unsubstituted or substituted with one or more groups listed in the definition of Z 1 , or (4) R 12 and R 13 together with the nitrogen atom to which they are attached may combine to form a group —N═C R 16 R 17 where R 16 and R 17 are each independently H or a group provided in the definition of R 10 ; and U 3 and U 4 are each independently (1) a single bond, (2) alkylene, (3) alkenylene, (4) alkynylene.