Patent ID: 8293720

Claim:
A compound of formula II or a stereoisomer or pharmaceutically acceptable salt thereof: wherein: R 1 and R 2 independently are selected from H and C 1-3 alkyl; Z is selected from cyclopropyl, cyclobutyl, cyclopentyl, tetrahydrofuranyl, azetidin-2-onyl, pyrrolidinyl, and pyrrolidin-2-onyl; Z is substituted with 0-2 Z 2 ; Z 2 is independently selected from F, C 1-4 alkyl, CF 3 , OCF 3 , (CH 2 ) a OR 3 , (CH 2 ) a NR 3 R 3 , NO 2 , (CH 2 ) a CN, (CH 2 ) a CO 2 R 3 , and (CH 2 ) a CONR 3 R 3 ; R 3 is independently selected from H and C 1-6 alkyl; R 4 is selected from CH 2 OR and C(O)NRR; each R independently is selected from H, C 1-4 alkyl, cyclobutyl, and (CH 2 ) a cyclopropyl; and a is selected from 0, 1, and 2.