Patent ID: 8772501

Claim:
A dye-conjugate having the formula: wherein X 1 and X 2 are independently S or O; Y 1 and Y 2 separately represent halogen, or Y 1 is CF 3 and Y 2 is H; Z 1 is H or alkyl; wherein Z 1 and one of the W groups may be absent and, if absent, are replaced with an additional bond between C 4 and C 5 in ring C; L is selected from the group consisting of a carbonyl group (C═O), —C(═O)NH(CH 2 ) n C(O)— wherein n is an integer from 1-5, and —(CH 2 ) n C(═O)— wherein n is an integer from 1-5; and wherein CM is a covalently linked conjugated molecule comprising a protein.