Patent ID: 7276531

Claim:
A gamma-lactam diene of Formula I: wherein A is selected from the group consisting of C 1 -C 4 alkyl, aryl, heteroaryl, C 3 -C 6 cycloalkyl and C 3 -C 6 heterocycloalkyl; B is C(O)Z wherein Z is selected from the group consisting of hydroxy, alkoxy, C 1 -C 6 alkyl, C 1 -C 6 heteroalkyl and NR 1 R 2 , wherein R 1 and R 2 are independently selected from the group consisting of H, C 3 -C 6 cycloalkyl, C 3 -C 6 heterocycloalkyl, aryl C 1 -C 6 alkyl and heteroaryl C 1 -C 6 alkyl; D is selected from the group consisting of H, halogen and C 1 -C 6 alkyl; E is selected from the group consisting of H and C 1 -C 6 alkyl; G is selected from the group consisting of H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 heterocycloalkyl, aryl C 1 -C 6 alkyl, heteroaryl C 1 -C 6 alkyl, aryl and heteroaryl; or E and G form, together with the carbon atom they are attached to, a C 3 -C 6 cycloalkyl ring; J, K and L are independently selected from the group consisting of H, halogen, C 1 -C 6 alkyl, aryl and heteroaryl; M is selected from the group consisting of OR and H, n is 0 or 1; wherein the (a) and (b) double bonds can be independently in Z or E conformation.