Patent ID: 7989639

Claim:
A method of preparing the lactate monohydrate salt of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide comprising the steps of: (a) suspending N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide free base monohydrate in acetone; (b) adding lactic acid dropwise with stirring at ambient temperature, wherein the lactic acid is present in an equimolar amount; (c) stirring the reaction mixture for a time sufficient to cause precipitation of the lactate monohydrate salt; and (d) cooling the reaction mixture.