Patent ID: 7589112

Claim:
A compound of formula II, wherein Ar 1 is phenyl, Ar 2 is pyridinyl, R 6 , R 7 are independently H or A, R 8 , R 9 and R 10 are independently selected from the group consisting of H, A, cycloalkyl comprising 3 to 7 carbon atoms, Hal, CH 2 Hal, CH(Hal) 2 , C(Hal) 3 , NO 2 , (CH 2 ) n CN, (CH 2 ) n NR 11 R 12 , (CH 2 ) n O(CH 2 ) k NR 11 R 12 , (CH 2 ) n NR 11 (CH 2 ) k NR 11 R 12 , (CH 2 ) n O(CH 2 ) k OR 11 , (CH 2 ) n NR 11 (CH 2 ) k OR 12 , (CH 2 ) n COOR 13 , (CH 2 ) n COR 13 , (CH 2 ) n CONR 11 R 12 , (CH 2 ) n NR 11 COR 13 , (CH 2 ) n NR 11 CONR 11 R 12 , (CH 2 ) n NR 11 SO 2 A, (CH 2 ) n SO 2 NR 11 R 12 , (CH 2 ) n S(O) u R 13 , (CH 2 ) n OC(O)R 13 , (CH 2 ) n COR 13 , (CH 2 ) n SR 11 , CH═N—OA, CH 2 CH═N—OA, (CH 2 ) n NHOA, (CH 2 ) n CH═N—R 11 , (CH 2 ) n OC(O)NR 11 R 12 , (CH 2 ) n NR 11 COOR 13 , (CH 2 ) n N(R 11 )CH 2 CH 2 OR 13 , (CH 2 ) n N(R 11 )CH 2 CH 2 OCF 3 , (CH 2 ) n N(R 11 )C(R 13 )HCOOR 12 , (CH 2 ) n N(R 11 )C(R 13 )HCOR 11 , (CH 2 ) n N(R 11 )CH 2 CH 2 N(R 12 )CH 2 COOR 11 , (CH 2 ) n N(R 11 )CH 2 CH 2 NR 11 R 12 , CH═CHCOOR 13 , CH═CHCH 2 NR 11 R 12 , CH═CHCH 2 NR 11 R 12 , CH═CHCH 2 OR 13 , (CH 2 ) n N(COOR 13 )COOR 14 , (CH 2 ) n N(CONH 2 )COOR 13 , (CH 2 ) n N(CONH 2 )CONH 2 , (CH 2 ) n N(CH 2 COOR 13 )COOR 14 , (CH 2 ) n N(CH 2 CONH 2 )COOR 13 , (CH 2 ) n N(CH 2 CONH 2 )CONH 2 , (CH 2 ) n CHR 13 COR 14 , (CH 2 ) n CHR 13 COOR 14 , (CH 2 ) n CHR 13 CH 2 OR 14 , (CH 2 ) n OCN and (CH 2 ) n NCO, wherein R 11 R 12 are independently selected from the group consisting of H, A and (CH 2 ), R 13 , R 14 are independently selected from the group consisting of H, Hal, A and (CH 2 ) m Ar 4 , A is selected from the group consisting of alkyl, alkenyl, cycloalkyl, alkylenecycloalkyl, alkoxy and alkoxyalkyl, Ar 3 , Ar 4 are independently aromatic hydrocarbon residues comprising 5 to 12 carbon atoms which are optionally substituted by one or more substituents, selected from the group consisting of A, Hal, NO 2 , CN, OR 15 , NR 15 R 16 , COOR 15 , CONR 15 R 16 , NR 15 COR 16 , NR 15 CONR 15 R 16 , NR 16 SO 2 A, COR 15 , SO 2 R 15 R 16 , S(O) u A and OOCR 15 , R 15 , R 16 are independently selected from the group consisting of H, A, and (CH 2 ) m Ar 6 , wherein Ar 6 is a 5- or 6-membered aromatic hydrocarbon which is optionally substituted by one or more substituents selected from the group consisting of methyl, ethyl, propyl, 2-propyl, tert.-butyl, Hal, CN, OH, NH 2 and CF 3 , k, n and m are independently of one another 0, 1, 2, 3, 4, or 5; X is O, Y is O or S, p, r are independently 0, 1, 2, 3, 4 or 5, q is 0, 1, 2, 3 or 4, u is 0, 1, 2 or 3, and Hal is selected from the group consisting of F, Cl, Br and I; and a pharmaceutically acceptable salt thereof.