Patent ID: 8383635

Claim:
A compound according to Formula I: wherein: R 1 is aryl, —CH 2 -aryl, or heteroaryl each of which is optionally substituted with one to three R5; R 2 is H, C 1 -C 6 alkyl optionally substituted with one or two R 6 , C 3 -C 6 cycloalkyl optionally substituted with one to three R 7 , or heterocycloalkyl optionally substituted with one to three R 7 ; and R3 is H, C 1 -C 6 alkyl, or phenyl; or R 2 and R 3 are joined together with the nitrogen atom to which they are attached forming a saturated 4-7 membered heterocycloalkyl which may contain one additional N, S, or O atom and being optionally substituted with one to three C 1 -C 3 alkyl groups optionally substituted with one OH, oxo, aryl, or —NR a R b ; R 4 is H, halo, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, cyano, C 1 -C 3 alkoxy, NR a R b , aryl optionally substituted with one to three R 5 , or heteroaryl optionally substituted with one to three R 6 ; each R 5 is independently selected from the group consisting of halo, CN, C 1 -C 3 alkoxy, heteroaryl, —S(O) 2 R a , —S(O) 2 NR a R b , —NR a S(O) 2 R a , —NR b C(O)R a , —C(O)NR a R b , —NR b C(O)NR a R b , and C 1 -C 3 alkyl optionally substituted by —NR a R b ; each R 6 is independently selected from the group consisting of OH, —NR a R b , —NR b C(O)R a , 1,1-cyclopropanedicarboxamide, heteroaryl, heterocycloalkyl, and aryl optionally substituted by S(O) 2 NH 2 ; each R 7 is independently selected from the group consisting of OH, C 1 -C 3 alkoxy, —NR a R b , and C 1 -C 3 alkyl optionally substituted by —NR a R b ; each R a is independently selected from the group consisting of H, heterocycloalkyl, and C 1 -C 3 alkyl optionally substituted with one —NH 2 or NHCH 3 ; and each R b is independently H or C 1 -C 6 alkyl; or a pharmaceutically acceptable salt thereof.