Patent ID: 8415356

Claim:
A compound according to formula I wherein A is N, CH or CR 1 ; each R 1 is independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, —C(O)—C 1-6 alkyl, —C(O)—C 2-6 alkenyl, —C(O)—C 2-6 alkynyl, —C(O)—O—C 1-6 alkyl, —C(O)—O—C 2-6 alkenyl, —C(O)—O—C 2-6 alkynyl, or phenyl, wherein said phenyl, C 1-6 alkyl, C 2-6 alkenyl or C 2-6 alkynyl is optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxyl, haloC 1-6 alkyl, nitro, C 1-6 alkoxy, and NR 2 R 3 ; X is hydrogen, C 1-6 alkyl or —CR a R b —X′, wherein X′ is a monocyclic saturated moiety having 5-6 ring atoms, one of which is N and wherein one or two additional ring atoms may be a hetero atom selected from the group consisting of N, O and S, which monocyclic ring may be substituted with one or more substituents W, wherein W is selected from the group consisting of C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and (═O); R a and R b are each independently hydrogen, —CH 3 or halogen; Y is a hetero aromatic moiety having 5-6 ring atoms, wherein 1-4 of said ring atoms are selected from the group consisting of N, O and S, which hetero aromatic moiety may optionally be benzofused, and which hetero aromatic moiety may be substituted with one or more substituents Z, wherein Z is selected from the group consisting of C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, cyano, halogen, hydroxy, C 1-6 alkoxy, C 1-6 haloalkyl, and NR 2 R 3 ; wherein each of R 2 and R 3 are independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, hydroxyC 1-6 alkyl, or haloC 1-6 alkyl; each of R 4 -R 8 and R 9 -R 12 are independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, halogen, NR 2 R 3 , hydroxy, cyano, nitro, C 1-6 alkoxy, haloC 1-6 alkyl or hydroxyC 1-6 alkyl; or a pharmaceutically acceptable salt thereof.