Patent ID: 8293769

Claim:
A compound that is of the Formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is O or S; A is a six-member ring where W is C—R 3 or N, each of Q 1 , Q 2 , Q 3 and Q 4 is independently C—R 3 or N, provided that at least one of Q 1 , Q 2 , Q 3 and Q 4 is N and at most three of Q 1 , Q 2 , Q 3 , Q 4 and W are N; R 1 is L-R 1b wherein L is a covalent bond, alkylene, or substituted alkylene, and R 1b is wherein R 10 , R 11 , and R 12 are independently selected from the group consisting of hydrogen, halo, hydroxy, alkyl, substituted alkyl, alkoxy, substituted alkoxy, amino, substituted amino, cycloalkyl, substituted cycloalkyl, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl; or R 11 is taken together with R 12 to form a group selected from the group consisting of aryl, substituted aryl, heterocyclyl, substituted heterocyclyl, heteroaryl, and substituted heteroaryl; R 2 is H or methyl; each R 3 is independently hydrogen or R 3a , where each R 3a is independently selected from the group consisting of halo, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, carbonitrile, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, amino, substituted amino, acyl, acylamino, alkoxy, substituted alkoxy, carboxyl, carboxyl ester, substituted sulfonyl, aminosulfonyl, and aminocarbonyl; or two R 3a groups on two adjoining carbon atoms are taken together with the carbon atoms bound thereto to form a group selected from aryl, substituted aryl, heterocyclic, substituted heterocyclic, heteroaryl, or substituted heteroaryl; each R 4 is independently alkyl, substituted alkyl, alkoxy, substituted alkoxy, amino, substituted amino, or halo; and n is 0, 1, or 2.