Patent ID: 7247654

Claim:
A compound of Formula (I): or a stereoisomer or a pharmaceutically acceptable salt or solvate form thereof, wherein: ring A is phenyl; wherein the phenyl is further substituted with 0-2 R 6 ; X is NR 7 ; R 1 is —CH 2 NR 1a R 1b or —C(═NR 1c )NHR 1d ; R 1a is, independently at each occurrence, H or C 1 -C 3 alkyl; R 1b is, independently at each occurrence, H or C 1 -C 3 alkyl; R 1c is, independently at each occurrence, H or C 1 -C 4 alkyl; R 1d is, independently at each occurrence, H or C 1 -C 4 alkyl; R 2 is Y-Z-R 2a ; Y is a bond, C 1 -C 8 alkylene substituted with 0-3 R 2d , C 2 -C 8 alkenylene substituted with 0-3 R 2d , or C 2 -C 8 alkynylene substituted with 0-3 R 2d ; Z is absent, —O—, —NR 2b —, —NR 2b C(O)—, —NR 2b C(O)O—, —NR 2b C(O)NR 2b —, —NR 2b S(O) 2 —, —S(O) 2 —, —C(O)O—, —C(O)NR 2b —, or —C(O)—; provided that X—Y-Z do not combine to form a N—O bond; R 2a is, independently at each occurrence, H, R 2c , C 1 -C 6 alkyl substituted with 1 R 2c , or C 1 -C 8 alkyl substituted with 0-3 R 2d ; R 2b is, independently at each occurrence, H, C 1 -C 3 alkyl or phenyl; R 2c is, independently at each occurrence, C 3 -C 6 monocycloalkyl substituted with 0-3 R 2e , phenyl substituted with 0-3 R 2e , or 5-6 membered unsaturated, partially unsaturated or saturated heterocycle consisting of carbon atoms and 1-4 heteratoms independently chosen from O, N, and S, and substituted with 0-3 R 2e ; R 2d is, independently at each occurrence, halogen, —CF 3 , C 1 -C 6 alkyl, or C 1 -C 6 alkoxy; R 2e is, independently at each occurrence, halogen, —CF 3 , C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —CN, —NO 2 , ═O, —OR 2f , —OC(O)R 2f , —OC(O)OR 2f , —OC(O)NR 2b R 2f , —NR 2b R 2f , —NR 2b C(O)R 2f , —NR 2b C(O)OR 2f , —NR 2b C(O)NR 2b R 2f , —NR 2b S(O) 2 R 2f , —NR 2b S(O) 2 NR 2b R 2f , —C(O)R 2f , —C(O)OR 2f , —C(O)NR 2b R 2f , —C(O)NHS(O) 2 R 2f , —S(O) 2 NHC(O)R 2f , or —C(O)NHC(O)R 2f ; R 2f is, independently at each ocurrence, H, C 1 -C 6 alkyl, phenyl, benzyl, or CF 3 ; R 3 is H, F, or CH 3 ; R 4 is H, F, or CH 3 ; alternatively, R 3 and R 4 are taken together to form —CH 2 CH 2 —, —CH 2 CH 2 CH 2 —, —CH 2 CH 2 CH 2 CH 2 —, or —CH 2 CH 2 CH 2 CH 2 CH 2 —; R 5 is: ring B is C 6 -C 10 aryl; R 6 is, independently at each ocurrence, H, C 1 -C 3 alkyl, halogen, —CF 3 , —OH, C 1 -C 3 alkoxy, or —OCF 3 ; R 7 is H, C 1 -C 6 alkyl, phenyl, benzyl, or phenethyl; R 8 is, independently at each ocurrence, H, halogen, —CF 3 , C 1 -C 6 alkyl, or C 1 -C 6 alkoxy; R 9 is, independently at each ocurrence, H, halogen, —CF 3 , C 1 -C 6 alkyl, or C 1 -C 6 alkoxy; and R 10 is, independently at each ocurrence, H, halogen, —CF 3 , C 1 -C 6 alkyl, or C 1 -C 6 alkoxy; provided that: when B is phenyl, R 2 is other than H or C 1 -C 3 alkyl.