Patent ID: 8088103

Claim:
A catheter comprising: a) a catheter shaft having a longitudinal axis, a distal end having a shaft distal tip, and a proximal end; b) a first balloon positioned on the shaft proximal to the shaft distal tip; c) a second balloon positioned on the shaft proximal to the first balloon; d) a third balloon positioned on the shaft proximal to the second balloon; e) an agent delivery segment positioned on the shaft between the first and third balloons and having one agent delivery segment orifice formed therein; f) an aspiration segment positioned on the shaft between the first and third balloons and having one aspiration segment orifice formed therein; and g) a guidewire lumen formed within the shaft and in communication with: an opening formed in a proximal end of the catheter; and an opening formed in a distal end of the catheter h) an agent delivery lumen in fluid communication with said agent delivery segment orifice, and a first pressure-sensing means having proximal and distal ends and a length therebetween extending through said agent delivery lumen, wherein said first pressure sensing means distal end is at the agent delivery segment orifice or within the agent delivery lumen, wherein said agent delivery segment orifice and said aspiration segment orifice lie on opposite sides of said longitudinal axis.