Patent ID: 8143280

Claim:
A compound of formula I: wherein: A is C—R 1b ; R 1a , R 1b , R 1c , R 1d and R 1e independently from each other selected from the group consisting of hydrogen, C 1-7 -alkyl, C 3-7 -cycloalkyl-C 1-7 -alkyl, halogen, halogen-C 1-7 -alkyl, halogen-C 1-7 -alkoxy, halogen-C 1-7 -alkyl-sulfonyloxy, hydroxy, hydroxy-C 1-7 -alkyl, C 1-7 -alkoxy, C 1-7 -alkoxy-C 1-7 -alkoxy, hydroxy-C 1-7 -alkoxy, amino-C 1-7 -alkoxy, cyano, carboxyl, carboxyl-C 1-7 -alkyl, carboxyl-C 1-7 -alkoxy, C 1-7 -alkoxycarbonyl, C 1-7 -alkoxycarbonyl-C 1-7 -alkoxy, C 1-7 -alkoxycarbonylamino-C 1-7 -alkoxy, C 1-7 -alkylcarbonyloxy-C 1-7 -alkoxy, aminocarbonyl-C 1-7 -alkoxy, di-C 1-7 -alkylamino, di-C 2-7 -alkenylamino, C 1-7 -alkylsulfonylamino, phenylcarbonylamino, phenylsulfonyloxy, heteroaryl-C 1-7 -alkoxy, wherein the heteroaryl ring is selected from the group consisting of oxadiazolyl, isoxazolyl, thiadiazolyl and tetrazolyl and is unsubstituted or substituted by C 1-7 -alkyl, phenyloxy and phenyl-C 1-7 -alkoxy, said phenyl ring being unsubstituted or substituted by one, two or three substituents selected from the group consisting of halogen, halogen-C 1-7 -alkyl, C 1-7 -alkyl, hydroxy, cyano, C 1-7 -alkylsulfonyl, C 1-7 -alkoxy and halogen-C 1-7 -alkoxy; or R 1c and R 1d or R 1d and R 1e together are —CH═CH—CH═CH— to form a phenyl ring together with the carbon atoms to which they are attached; R 2 is selected from the group consisting of C 1-7 -alkyl, C 3-7 -cycloalkyl-C 1-7 -alkyl, carboxyl-C 1-7 -alkyl, C 1-7 -alkoxycarbonyl-C 1-7 -alkyl, triazolyl-C 1-7 -alkyl and phenyl, said phenyl being unsubstituted or substituted by one, two or three halogen groups; R 3 is hydrogen or C 1-7 -alkyl; R 4 is pyridyl, unsubstituted or substituted by one, two or three substituents selected from the group consisting of halogen, halogen-C 1-7 -alkyl, cyano, C 1-7 -alkyl, C 3-7 -cycloalkyl-C 1-7 -alkyl, C 1-7 -alkoxy, C 1-7 alkoxy-C 1-7 -alkoxy, cyano-C 1-7 -alkoxy, hydroxy-C 1-7 -alkoxy, halogen-C 1-7 -alkoxy, carboxyl, carboxyl-C 1-7 -alkyl, carboxyl-C 1-7 -alkoxy, C 1-7 -alkoxycarbonyl, C 1-7 -alkoxycarbonyl-C 1-7 -alkyl, C 1-7 alkoxycarbonyl-C 1-7 -alkoxy, R 6 R 7 N-carbonyl-C 1-7 -alkoxy, wherein R 6 and R 7 are independently selected from hydrogen or C 1-7 -alkyl or R 6 and R 7 together with the nitrogen atom they are attached to form a heterocyclic ring selected from pyrrolidine, piperidine, morpholine or thiomorpholine, phenyl, said phenyl being unsubstituted or substituted by one, two or three substituents selected from the group consisting of halogen, halogen-C 1-7 -alkyl, hydroxy, cyano, carboxyl, C 1-7 -alkyl, alkoxycarbonyl and C 1-7 -alkoxy; pyridyl, heterocyclyl selected from the group consisting of pyrrolidine and piperidine, said heterocyclyl ring being unsubstituted or substituted by carboxyl or C 1-7 -alkoxy-carbonyl, phenyl-C 1-7 -alkyl, phenyloxy and phenyl-C 1-7 -alkoxy; R 5 is hydrogen or methyl; n is 0 or 1; or a pharmaceutically acceptable salt thereof.