Patent ID: 6956036

Claim:
A compound of the formula: wherein R 1 to R 4 are independently chosen from hydrogen, halogen, C 1-6 alkyl, trifluoromethyl, O—W, C 1-6 alkylthio, C 1-6 alkylsulfoxyl, C 1-6 alkylsulfonyl, or cyano; R 5 is halogen, trifluoromethyl, cyano, or NR 10 R 11 ; R 6 and R 7 are independently chosen from hydrogen, C 1-4 alkyl or R 6 , R 7 and the carbon atom to which they are attached form a cyclopropyl ring, or furthermore, R 7 and R 8 together are (CH 2 ) m to form a saturated heterocycle; R 8 and R 9 are independently chosen from hydrogen or C 1-4 alkyl; R 10 and R 11 are independently chosen from hydrogen or C 1-4 alkyl, or R 10 , R 11 and the nitrogen atom to which they are attached form a saturated heterocyclic ring selected from pyrrolidine, piperidine, piperazine, or morpholine; R 1 to R 4 are not simultaneously hydrogen; R 6 and R 7 are not both hydrogen; W is hydrogen, C 1-4 alkyl, C(═O)X, or P(═O)(OY)(OZ); X is C 1-6 alkyl, NR 8 R 9 , N(R 8 )CH 2 (CH 2 ) n C(═O)N(R 8 )(R 9 ), OC 1-6 alkyl, C 1-6 alkyl, C 2-4 alkenyl, wherein said C 1-6 alkyl is optionally substituted with halogen, hydroxyl, CO 2 C 1-4 alkyl, CON(C 1-4 alkyl) 2 , C(═NH)NH 2 , NHC(═NH)NH 2 , or NH 2 , and wherein said C 2-4 alkenyl is optionally substituted by phenyl, unsubstituted or substituted with one or more of C 1-4 alkyl, C 1-4 alkoxy or halogen; Y and Z are independently chosen from hydrogen, C 1-10 alkyl or Y and Z together form a lower alkyl chain of (CH 2 ) m ; m is 3 or 4; n is 1 or 2; and pharmaceutically acceptable salts and solvates of the compound.