Patent ID: 8232409

Claim:
A compound of the formula (I) wherein W 1 is C(R 2a ) or N; W 2 is CH or N; W 3 is C(R 2 ) or N; such that no more than one of W 1 , W 2 , and W 3 is N; and when one of W 1 , W 2 , and W 3 is N, then R 2 and R 2a are hydrogen; R 1 is fluoro, chloro, trifluoromethyl, (1-hydroxy-1-methyl)ethyl, 2,2,2trifluoroethyl, trifluoromethoxy, or difluoromethoxy; or R 1 and R 3 are taken together to form a single fused —OCF 2 O— moiety; R 1a is hydrogen, fluoro, chloro, or bromo; R 2 is hydrogen, C 1-4 alkyl, fluoro, chloro, bromo, cyano, trifluoromethyl, hydroxy(C 1-6 )alkyl, C 1-3 alkoxy(C 1-6 )alkyl, cyclopropyl, —CH═CHCH 2 OH, or C 2-4 alkenyl bound via an unsaturated carbon atom; R 2a is hydrogen or methyl; R 3 is hydrogen, fluoro, or taken with R 1 to form —OCF 2 O—; V and Q are selected from the group consisting of V is CH(R 4 ) and Q is O; V is NH and Q is CH 2 ; and V is O and Q is CH 2 ; R 4 is hydrogen or C 1-4 alkyl; X is CH 2 , C(CH 3 ) 2 , CF 2 , or O; with the proviso that when V is NH, X is other than O; or enantiomers, diastereomers, or pharmaceutically acceptable salts thereof.