Patent ID: 7825258

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt or ester thereof, wherein R 1 is cycloalkyl or aryl, wherein said cycloalkyl or aryl is optionally substituted with 1 to 4 substituents independently selected from the group consisting of hydroxy, halogen, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl and fluoro-lower-alkoxy; R 2 is hydrogen or lower-alkyl; R 3 is cycloalkyl, wherein said cycloalkyl is optionally substituted with 1 to 4 substituents independently selected from the group consisting of hydroxy, halogen, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl, fluoro-lower-alkoxy and lower-alkoxy-carbonyl; R 4 is phenyl optionally substituted with 1 to 4 substituents independently selected from the group consisting of halogen, lower-alkyl, lower-alkoxy, hydroxy, dioxo-lower-alkylene, fluoro-lower-alkyl and fluoro-lower-alkoxy; R 5 and R 6 independently from each other are hydrogen, hydroxy, hydroxy-lower-alkyl, lower-alkoxy, lower-alkyl, fluoro-lower-alkyl or fluoro-lower-alkoxy; R 7 , R 8 , R 9 and R 10 independently from each other are hydrogen, halogen, hydroxy, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl or fluoro-lower-alkoxy.