Patent ID: 8436150

Claim:
An isolated aglycosylated IgG1 antibody or fragment thereof, wherein said antibody or fragment (i) specifically binds c-Kit, (ii) comprises six CDRs, and (iii) one of said CDRs comprises amino acids 43 to 58 of SEQ ID NO: 2, another of said CDRs comprises amino acids 74 to 80 of SEQ ID NO: 2, another of said CDRs comprises amino acids 113 to 121 of SEQ ID NO: 2, another of said CDRs comprises amino acids 50 to 54 of SEQ ID NO: 4, another of said CDRs comprises amino acids 69 to 85 of SEQ ID NO: 4, and another of said CDRs comprises amino acids 118 to 125 of SEQ ID NO: 4.