Patent ID: 7521442

Claim:
A compound of formula I where: R 1 is CO 2 R 5 or CONR 6 R 7 ; R 2 is azetidinyl substituted with 0-2 substituents selected from the group consisting of halo, hydroxy, alkyl, cycloalkyl, haloalkyl, alkoxy, haloalkoxy, OP(O)(R 11 ) 2 , and phenyl where the phenyl is substituted with 0-2 substituents selected from halo, alkyl, and alkoxy; R 3 is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, or alkoxy; R 4 is cycloalkyl; R 5 is hydrogen or alkyl; R 6 is hydrogen, alkyl, alkylSO 2 , cycloalkylSO 2 , haloalkylSO 2 , (R 8 ) 2 NSO 2 , or (R 9 )SO 2 ; R 7 is hydrogen or alkyl; R 8 is hydrogen or alkyl; R 9 is azetidinyl, pyrrolidinyl, piperidinyl, N—(R 10 )piperazinyl, morpholinyl, thiomorpholinyl, homopiperidinyl, or homomorpholinyl; R 10 is hydrogen or alkyl; R 11 is hydroxy, alkoxy, or benzyloxy; and the carbon bearing the asterisk is of the (R) configuration or the (S) configuration; or a pharmaceutically acceptable salt thereof.