Patent ID: 8486928

Claim:
A compound of formula (1): wherein: each R 1 is independently C1-C10 alkyl, C6-C10 aryl, C5-C10 heteroaryl, or (C6-C10 aryl)-(C1-C4 alkyl), or (C5-C10 heteroaryl)-(C1-C4 alkyl), each of which can be substituted with one or more groups selected from halo, ═O, OR, S(O) t R, NR 2 , COOR, CONR 2 , wherein t can be 0-2 and each R independently represents H, C1-4 alkyl, and wherein two R groups on one N can cyclize to form a saturated azacyclic group; each R 2 is independently C1-C10 alkyl, C6-C10 aryl, C5-C10 heteroaryl, or (C6-C10 aryl)-(C1-C4 alkyl), or (C5-C10 heteroaryl)-(C1-C4 alkyl), each of which can be substituted with one or more groups selected from halo, OR, S(O) t R, NR 2 , COOR, CONR 2 , wherein t can be 0-2 and each R independently represents H, C1-C4 alkyl, and wherein two R groups on one N can cyclize to form a saturated azacyclic group; each R 3 is H or a protecting group; wherein any two R 1 on a single carbon can cyclize to form a ring having 3-8 ring atoms, which ring can be substituted, and which can contain a heteroatom selected from N, O and S as a ring member; and any two R 1 on adjacent carbon atoms, and any two R 2 groups on adjacent carbon atoms, can cyclize to form a ring having 3-8 ring atoms, which ring can be substituted and can be aromatic or non-aromatic, and can contain a heteroatom selected from N, O and S as a ring member; and any two of R 1 and R 2 on carbon atoms separated by a single Nitrogen atom can cyclize to form a ring having 3-8 atoms, which ring can be substituted and can be aromatic or non-aromatic, and can contain, in addition to the N between the carbon atoms to which linked groups are attached, an additional heteroatom selected from N, O and S as a ring member; each m is independently 0 or 1; each n and p is independently 0-2; L represents a three-atom linker that may be —C(R 1 ) p —NR 3 —C(R 1 ) p — or an optionally substituted pyridine-2,6-diyl group; and M represents H or a metal cation; or a pharmaceutically acceptable salt thereof.