Patent ID: 8445538

Claim:
A compound represented by formula I: or a pharmaceutically acceptable salt thereof wherein: each R 1 represents H or is selected from the group consisting of halo, CN, OH, NO 2 , CO 2 R a , NR a R b , S(O) p R a , C 1-10 alkyl, C 2-10 alkenyl or C 1-10 alkoxy, the alkyl and alkenyl portions of, C 1-10 alkyl, C 2-10 alkenyl and C 1-10 alkoxy being optionally substituted with 1-5 halo atoms up to perhalo; and further optionally substituted with 1 group selected from OH, oxo and C 1-6 alkoxy; p represents 0, 1 or 2; each R a and R b independently represents H or C 1-4 alkyl optionally substituted with 1-5 halo atoms up to perhalo; and further optionally substituted with 1 group selected from OH, oxo and C 1-6 alkoxy; R 2 represents C 1-6 alkyl or C 2-6 alkenyl, each optionally substituted with 1-5 halo atoms up to perhalo, and further optionally substituted with 1 group selected from OH, oxo and C 1-6 alkoxy; R 3 represents H or is selected from the group consisting of halo, CN, OH, NO 2 , CO 2 R a , NR a R b , S(O) p R a , C 1-10 alkyl, C 2-10 alkenyl and C 1-10 alkoxy, the alkyl and alkenyl portions of, C 1-10 alkyl, C 2-10 alkenyl and C 1-10 alkoxy being optionally substituted with 1-5 halo atoms up to perhalo; and further optionally substituted with 1 group selected from OH, oxo, NR a R b , and C 1-6 alkoxy; each R 4 independently represents H or is selected from the group consisting of halo, OH, C 1-4 alkyl, OC 1-4 alkyl, haloC 1-4 alkyl and haloOC 1-4 alkyl; m represents 0, 1 or 2; when m represents 0, Z represents tetrazolyl; when m represents 1, Z represents a member selected from the group consisting of CO 2 H, SO 3 H, C(O)NH 2 and tetrazolyl; and when m represents 2, Z represents a member selected from the group consisting of CO 2 H, SO 3 H and C(O)NH 2 .