Patent ID: 8835457

Claim:
A compound of Formula I: wherein: R 1 is substituted aryl; Q is (CR 4 R 5 ) v C(═O), (CR 4 R 5 ) v SO 2 , or (CR 4 R 5 ) v , in which C(═O) and SO 2 are connected to ring; v is 0, 1, 2, or 3; R 2 is selected from the following heteroaryl systems, optionally substituted: ring is selected from the following bridged bicyclic systems: in which N of ring is connected to Q, and the other line is connected to NR 2 R 3 ; i and n are independently 1, 2, or 3; j, k, l, and m are independently 0, 1, or 2; the ring is optionally substituted by alkyl, cycloalkyl, aryl, heteroaryl, heterocycle, halo, oxo, OR 6 , NR 6 R 7 , or SR 6 ; R 3 -R 7 are independently H, alkyl, alkenyl, alkynyl, aryl, arylalkyl, arylalkenyl, arylalkynyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkylalkenyl, cycloalkylalkynyl, heteroaryl, heteroarylalkyl, heteroarylalkenyl, heteroarylalkynyl, heterocycle, (heterocycle)alkyl, (heterocycle)alkenyl, (heterocycle)alkynyl, optionally substituted; when ring is ring-1, then 1≦j+k+l+m≦6; when ring is ring-2, then 1≦j+k+l+n≦6, and when ring is ring-3, then 2≦j+k+n≦6.