Patent ID: 7348349

Claim:
A method for the treatment of a disease selected from the group consisting of diabetes, non-insulin dependent diabetes mellitus, elevated blood pressure, increased lipid and cholesterol levels, atherosclerotic diseases and metabolic syndrome comprising administering, to a patient in need thereof, a therapeutically effective amount of an optically active compound according to formula (I): wherein: (a) R 1 is aryl; (b) R 2 is selected from the group consisting of lower-alkyl and fluoro-lower-alkyl; (c) R 3 and R 4 independently from each other are selected from the group consisting of hydrogen, hydroxy, halogen, lower-alkyl, fluoro-lower-alkyl, hydroxy-lower-alkyl, lower-alkoxy-lower-alkyl, lower-alkoxy, fluoro-lower-alkoxy, hydroxy-lower-alkoxy, lower-alkoxy-lower-alkoxy, and lower-alkenyl; wherein at least one of R 3 and R 4 is not hydrogen; (d) R 5 is selected from the group consisting of lower-alkoxy, fluoro-lower-alkoxy, lower-alkenyloxy, fluoro-lower-alkenyloxy, aryloxy, aryl-lower-alkoxy, and aryl-fluoro-lower-alkoxy; (e) R 6 is selected from the group consisting of hydrogen and lower-alkyl; and (f) n is 1; or pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof.