Patent ID: 7737174

Claim:
A compound having Formula I: or a pharmaceutically acceptable salt thereof, wherein: X is N; Y is O, or S; R 1 , R 2 , R 4 , R 5 , R 6 , and R 7 are independently H or optionally substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, heterocyclic, CO 2 R′, OCOR′, CONR′R″, NR″COR′, NR′SO 2 R″, SO 2 NR′R″, (C═NR′)NR″R′″, or NR′R″; or R 7 forms an aryl, cycloalkyl, or heterocyclic group with one of R 5 or R 6 ; R 8 is H or optionally substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, heterocyclic, CO 2 R′, OCOR′, CONR′R″, SO 2 NR′R″, or (C═NR′)NR″R′″; each R′, R″ and R′″ is independently H or optionally substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, or heterocyclic; or R′ and R″, or R″ and R′″, form a ring; and R 3 is CONHR 11 wherein R 11 is an optionally substituted cycloalkyl-alkyl or monoheterocycloalkyl-alkyl group or a dihydroxyalkyl group not containing a hydroxyl group at the 3-position of the alkyl group.