Patent ID: 8110686

Claim:
A compound having the following formula: wherein: R 1 is selected from the group consisting of: ethylamino, isopropylamino, Y is S; R 5′ is hydrogen; R 5 is selected from ethyl, C 3 -C 12 branched alkyl, C 2 -C 8 (alkylene)R 14 , cycloalkyl, —CH 2 (heterocyclyl), —CH 2 (aryl), heterocyclyl, and R 4 is selected from 5-6 membered heterocyclyl, R 9 -substituted heteroaryl, or p-R 9 -substituted phenyl; each R 9 is selected from F; Cl; Br; I; OH; —CN; —N(CN) 2 ; —C(CN) 3 ; —CF 3 ; —(CF 2 ) m CF 3 , wherein m is zero, one, two, or three; —CH(CF 3 ) 2 , —CF(CF 3 ) 2 , —SO 3 H, C 2 -C 12 alkylsulfanyl, C 2 -C 12 alkoxy, substituted C 2 -C 12 alkoxy, —C(X) R 10 , tetrazolyl, 3-hydroxy-isoxazole-4-yl, and 3-hydroxy-isoxazole-5-yl; R 14 is —C(X) R 10 , X is O, NH 2 , NCN, NNO 2 ; and R 10 is selected from —OH, amino, alkylamino, CF 3 , NHCN, and 5-6-membered heterocyclyl; or a pharmaceutically acceptable salt thereof.