Patent ID: 8742115

Claim:
A co-crystal of a compound of formula 1 wherein R 1 is C 1-6 -alkyl, C 1-6 -haloalkyl, O—C 1-6 -haloalkyl, halogene; m is 1, 2 or 3; R 2a and R 2b are each independently selected from H, C 1-6 -alkyl, C 1-6 -alkenyl, C 1-6 -alkynyl, C 3-6 -cycloalkyl, COO—C 1-6 -alkyl, O—C 1-6 -alkyl, CONR 2b.1 R 2b.2 , halogene; R 2b.1 is H, C 1-6 -alkyl, C 0-4 -alkyl-C 3-6 -cycloalkyl, C 1-6 -haloalkyl; R 2b.2 is H, C 1-6 -alkyl; or R 2b.1 and R 2b.2 are together a C 3-6 -alkylene group forming with the nitrogen atom a heterocyclic ring, wherein optionally one carbon atom or the ring is replaced by an oxygen atom R 3 is H, C 1-6 -alkyl; X is an anion selected from the group consisting of chloride, bromide, iodide, sulphate, phosphate, methanesulphonate, nitrate, maleate, acetate, benzoate, citrate, salicylate, fumarate, tartrate, dibenzoyltartrate, oxalate, succinate, benzoate and p-toluenesulphonate; j is 0, 0.5, 1, 1.5 or 2; with a co-crystal former selected from the group consisting of orotic acid, hippuric acid, L-pyroglutamic acid, D-pyroglutamic acid, nicotinic acid, L-(+)-ascorbic acid, saccharin, piperazine, 3-hydroxy-2-naphtoic acid, mucic (galactaric) acid, pamoic (embonic) acid, stearic acid, cholic acid, deoxycholic acid, nicotinamide, isonicotinamide, succinamide, uracil, L-lysine, L-proline, D-valine, L-arginine, glycine.