Patent ID: 8003098

Claim:
A method for treating a pancreatic cancer expressing EphA4 in a subject comprising the step of administering to said subject an amount of an antibody that specifically binds to Eph4A, wherein the antibody comprises a heavy chain variable domain (VH) comprising the complementarity determining region (CDR) amino acid sequences of SEQ ID NO: 10(VH-CDR1), SEQ ID NO:11 (VH-CDR2) and SEQ ID NO:12 (VH-CDR3) separated by antibody framework amino acid sequences and a light chain variable domain (VL) comprising the CDR amino acid sequences of SEQ ID NO:15 (VL-CDR1), SEQ ID NO:16(VL-CDR2) and SEQ ID NO:17 (VL-CDR3) separated by antibody framework amino acid sequences, wherein the antibody causes antibody-dependent cytotoxicity, complement-dependent cytotoxicity or both and wherein the amount administered is effective to treat said pancreatic cancer expressing EphA4.