Patent ID: 7939552

Claim:
A benzyloxypropylamine derivative represented by the following formula (I) or a pharmaceutically acceptable salt thereof, wherein in the formula, R 1a and R 1b , which may be the same or different, is hydrogen, halogen, C 1-4 alkyl or trifluoromethyl; R 2 is phenyl which may be optionally substituted with halogen or diphenylmethyl; R 3 is hydrogen, C 1-4 alkyl or acetoxymethyl; and R 4 is a substituent selected from the following (a) to (j): (a) piperidinyl which may be optionally substituted with C 1-4 alkyl, piperidinyl, carboxymethyl, tert-butoxycarbonyl, tert-butoxycarbonylmethyl or amino, (b) piperidinylamino which may be optionally substituted with tert-butoxycarbonyl, (c) piperidinylmethyl which may be optionally substituted with carboxy or tert-butoxycarbonyl, (d) pyridyl which may be optionally substituted with one or two group(s) selected from C 1-4 alkyl, C 1-4 alkoxy, halogen, hydroxy, oxy, amino, carboxy and benzyl, (e) C 1-4 alkyl which is substituted with pyridyl, oxypyridyl, carboxy, amino or tert-butoxycarbonylamino, (f) C 2-4 alkenyl which is substituted with pyridyl or oxypyridyl, (g) phenyl which may be optionally substituted with a group selected from hydroxy, carboxy, ethoxycarbonyl, halogen, a C 1-4 alkyl which may be optionally substituted piperidinyl, pyrrolidinyl, amino, halogen or tert-butoxycarbonylamino and amino which may be optionally substituted with one or two C 1-4 alkyl or tert-butoycarbonyl, (h) cyclohexyl which is substituted with amino or tert-butoxycarbonylamino, (i) pyrazinyl and (j) quinolyl.