Patent ID: 7205321

Claim:
A compound is represented by the following structural formula: and pharmaceutically acceptable salts, solvates and hydrates thereof, wherein: (a) X is selected from the group consisting of an optionally substituted C 1 –C 3 alkylene linker wherein one carbon atom of the linker may be replaced with O, NH or S; (b) R3 is selected from the group consisting of H, C 1 –C 5 alkyl, and C 1 –C 5 alkoxy; (c) R4 is selected from the group consisting of H, a substituted or unsubstituted group selected from the group consisting of C 1 –C 5 alkyl, C 1 –C 5 alkoxy, C 3 –C 6 cycloalkyl and phenyl; and R3 and R4 are optionally combined to form a C 3 –C 4 cycloalkyl; (d) V is selected from the group consisting of a bond and a unsubstituted or substituted C1–C3 alkylene group; and (e) R6, R21, R22, R23 and R23 are each independently selected from the group consisting of H, OH, C1–C5 alkyl, alkoxy, halo, haloalkyl, haloalkoxy, nitro, phenyl, aryloxy, SO2R7, SR7, cyano, benzyloxy, phenoxy, alkylcarboxamido; or COOH wherein R7 is an alkyl or a haloalkyl.