Patent ID: 8501234

Claim:
A reverse vesicle composition comprising the following ingredients (A), (B), (C), (D), and (F): (A) a sphingosine represented by formula (1): from 0.001 to 10 mass % based on the total composition, wherein R 1 represents a C4 to C30 linear alkyl group which may be substituted by a hydroxyl group, a carbonyl group, or an amino group; Y represents a methylene group, a methine group, or an oxygen atom; each of X 1 , X 2 , and X 3 represents a hydrogen atom, a hydroxyl group, or an acetoxy group; X 4 represents a hydrogen atom, an acetyl group, or a glyceryl group, or forms an oxo group together with the adjacent oxygen atom; wherein when Y is a methine group, one of X 1 and X 2 is a hydrogen atom, and the other is absent, and when X 4 forms an oxo group, X 3 is absent; each of R 2 and R 3 represents a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; a is a number of 2 or 3; each of (R) a represents a hydrogen atom, an amidino group, or a linear-chain alkyl group optionally having a substituent selected from the group consisting of a hydroxyl group, a hydroxyalkoxy group, an alkoxy group, and an acetoxy group and containing 1 to 8 carbon atoms in total; and the broken line represents an optional unsaturated bond, (B) a C16 to C30 fatty acid, from 0.001 to 10 mass % based on the total composition, (C) a hydrocarbon oil, from 0.1 to 50 mass % based on the total composition, (D) an ester oil which is in liquid form at 25° C., from 0.01 to 50 mass % based on the total composition, and (F) water, wherein the ratio by mass of ingredient (C) to ingredient (D) satisfies the following relationship: 1≦(C)/(D)<1000, and the composition contains a surfactant having a molecular weight of 1,000 or less in an amount of 1 mass % or less, and wherein the reverse vesicle composition has a reverse vesicle structure in which the vesicle interface is a lipid bi-layer membrane and in which there is anisotropy at the vesicle interface.