Patent ID: 7026487

Claim:
A compound of the formula where X is O, S, or C(R) 2 ; R is H or alkyl of 1 to 6 carbons; R 1 is H, alkyl of 1 to 10 carbons, alkenyl of 2 to 6 carbons; phenyl-C 1 -C 6 alkyl, or C 1 -C 6 -alkylphenyl; R 2 is H, alkyl of 1 to 6 carbons, F, Cl, Br, I, CF 3 , fluoro substituted alkyl of 1 to 6 carbons, alkoxy of 1 to 6 carbons, or alkylthio of 1 to 6 carbons; R 3 is independently alkyl of 1 to 6 carbons, F, Cl, Br, I, CF 3 , fluoro substituted alkyl of 1 to 6 carbons, OH, SH, alkoxy of 1 to 10 carbons, fluoroalkoxy of 1 to 6 carbons, alkylthio of 1 to 6 carbons; benzyloxy C 1 -C 6 alkyl substituted benzyloxy, halogen substituted benzyloxy, phenyloxy, C 1 -C 6 alkyl substituted phenyloxy, or halogen substituted phenyloxy; R 4 is independently H, alkyl of 1 to 6 carbons, or F; Y is a group, said pyridyl group being optionally substituted with one or two R 2 groups; m is an integer having the values 0 to 3; o is an integer having the values 0 to 4; A is (CH 2 ) q where q is 0-5, lower branched chain alkyl having 3-6 carbons, cycloalkyl having 3-6 carbons, alkenyl having 2-6 carbons and 1 or 2 double bonds, alkynyl having 2-6 carbons and 1 or 2 triple bonds, and B is COOH, COOR 8 , CONR 9 R 10 , —CH 2 OH, CH 2 OR 11 , CH 2 OCOR 11 , CHO, CH(OR 12 ) 2 , CHOR 13 O, —COR 7 , CR 7 (OR 12 ) 2 , CR 7 OR 13 O, or tri-lower alkylsilyl, where R 7 is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons, R 8 is an alkyl group of 1 to 10 carbons or trimethylsilylalkyl where the alkyl group has 1 to 10 carbons, or a cycloalkyl group of 5 to 10 carbons, or R 8 is phenyl or lower alkylphenyl, R 9 and R 10 independently are hydrogen, an alkyl group of 1 to 10 carbons, or a cycloalkyl group of 5-10 carbons, or phenyl or lower alkylphenyl, R 11 is lower alkyl, phenyl or lower alkylphenyl, R 12 is lower alkyl, and R 13 is divalent alkyl radical of 2-5 carbons, or a pharmaceutically acceptable salt of said compound.