Patent ID: 8354423

Claim:
A compound of formula I: wherein X is NR 11 ; R 11 is hydrogen or C 1-6 alkyl; Y is C═O; R 1 is hydrogen, C 1-6 alkyl, C 1-6 haloalkyl, heteroaryl(C 1-3 )alkyl wherein the heteroaryl group may be optionally substituted by halogen, cyano, C 1-6 alkyl, or C 1-6 haloalkyl and where the heteroaryl group is a thiazole, pyridine, pyrimidine, pyrazine or pyridazine ring, heteroaryl optionally substituted by halogen, cyano, C 1-6 alkyl, or C 1-6 haloalkyl and where the heteroaryl group is a pyridine, pyrimidine, 2,1,3-benzoxadiazole, pyrazine or pyridazine ring, C 1-6 alkoxy, C 1-6 alkylamino, or heteroaryl(C 1-3 )alkylamino wherein the heteroaryl group may be optionally substituted by halogen, cyano, C 1-6 alkyl, or C 1-6 haloalkyl and where the heteroaryl group is a thiazole, pyridine, pyrimidine, pyrazine or pyridazine ring; R 2 and R 3 are both hydrogen; each R 4 is independently fluoro, chloro, bromo, cyano, cyano, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 cyanoalkyl or C 1-3 alkoxy (C 1-3 ) alkyl; n is 0, 1 or 2; each Ra is hydrogen; p and q are both 2; R 8 is phenyl(C 1-4 )alkyl wherein the phenyl group is optionally substituted by halogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 haloalkyl, C 1-4 haloalkoxy, CN, NO 2 , aryl, heteroaryl, amino or dialkylamino, heteroaryl(C 1-6 )alkyl wherein the heteroaryl group is optionally substituted by halogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 haloalkyl, C 1-4 haloalkoxy, CN, NO 2 , aryl, heteroaryl, amino or dialkylamino, phenyl(C 2-6 )alkenyl wherein the phenyl group is optionally substituted by halogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 haloalkyl, C 1-4 haloalkoxy, CN, NO 2 , aryl, heteroaryl, amino or dialkylamino, heteroaryl(C 2-6 )alkenyl wherein the heteroaryl group is optionally substituted by halogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 haloalkyl, C 1-4 haloalkoxy, CN, NO 2 , aryl, heteroaryl, amino or dialkylamino, or —C(R 51 )(R 52 )—[CR 53 ═CR 54 ]z-R 55 ; z is 1 or 2; R 51 and R 52 are each independently H, halogen or C 1-2 alkyl; R 53 and R 54 are each independently H, halogen, C 1-4 alkyl or C 1-4 haloalkyl; and R 55 is optionally substituted aryl or optionally substituted heteroaryl; wherein the heteroaryl group of R 8 is selected from a pyridine, pyrimidine, triazine, thienyl, furyl, oxazoline, isoxazole, 2,1,3-benzoxadiazole or thiazole ring; or salts thereof.