Patent ID: 7919621

Claim:
A compound having a structure represented by Formula (IIIc): wherein: G 1 is CR 1 ; G 4 is CR 1 ; each R 1 is independently H, halide, —CN, —NO 2 , —OH, —OR 3 ,—SR 3 , —S(═O)R 3 , —S(═O) 2 R 3 , —C(═O)R 3 , —C(═O)OR 3 , —CH(R 3 ) 2 , —N(R 3 ) 2 , —NHCH 2 C(═O)OR 3 , —C(═O)N(R 3 ) 2 , —NHC(═O)R 3 , or —C(OH)(R 3 ) 2 , C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 8 cycloalkyl, or C 1 -C 6 fluoroalkoxy; or R 1 is Q 1 -Q 2 where Q 1 is phenyl or monocyclic heteroaryl; and Q 2 is H, halide, —CN, —NO 2 , C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —OR 3 ,—SR 3 , —S(═O)R 3 , —S(═O) 2 R 3 , —C(═O)R 3 , —C(═O)OR 3 , —CH(R 3 ) 2 , —N(R 3 ) 2 , or —C(═O)N(R 3 ) 2 ; each R 3 is independently H, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, phenyl, or benzyl; L 1 is —(CHR 4 ) n X 1 (CHR 4 ) n — wherein, each n is independently 0, or 1; X 1 is a O, S, S(═O), or S(═O) 2 ; each R 4 is H; R 6 and R 7 are independently H, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl, or C 3 -C 8 cycloalkyl; or R 6 and R 7 can together form an optionally substituted a 5-, or 6-membered non-aromatic monocyclic ring containing 0 or 1 oxygen atom, wherein the ring is optionally substituted with F, —CH 3 or —CF 3 ; R 8 is H, —OH, —CONH 2 , tetrazolyl, —CN, —CO 2 H, —OR 12 , —CON(R 12 ) 2 , —CO 2 —R 12 , C(═O)R 12 , C(OH)(R 12 ) 2 , —CH═N—OR 12 , —N(R 12 ) 2 , NHC(═O)R 12 , or —OC(═O)R 12 ; where each R 12 is independently H, or C 1 -C 6 alkyl; R 9 is H; R 13 is H, C 1 -C 6 alkyl, or halide; R 14 is H, C 1 -C 6 alkyl, or halide; or a pharmaceutically acceptable salt, or pharmaceutically acceptable N-oxide thereof.