Patent ID: 8691865

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein L 1 -R 1 taken together are G 1 ; L 2 is —(CR c R d ) p —, C(O), C(O)N(R 4 ), S(O) 2 , SO 2 N(R 5 ), or C(O)O; R 2 is alkyl, haloalkyl, hydroxyalkyl, G 2 , -G 2 -G 3 , —C(R c )(G 2 )(G 3 ), —CH(OH)CF 3 , —(CR c R d ) p —CH(OH)CF 3 , —(CR c R d ) p -G 2 , —(CR c R d ) p —CH(G 2 )(G 3 ), —(CR g R h ) q —N(R 5 )—C(O)O(alkyl), —(CR g R h ) q —N(R 5 )—C(O)O-G 2 , —(CR g R h ) q —N(R 5 )—C(O)(alkyl), —(CR g R h ) q —N(R 5 )—SO 2 R 6 , —(CR g R h ) q —N(R 4 )(R 5 ), —(CR g R h ) q —N(R 5 )—C(O)N(R 5 )-(alkyl), —(CR g R h ) q —N(R 5 )—C(O)N(R 5 )-G 2 , or —C(O)N(R 4 )(R 5 ); or p, at each occurrence, is 1, 2, 3, 4, 5, or 6; q, at each occurrence, is 1, 2, 3, 4, or 5; R c and R d , at each occurrence, are each independently hydrogen, alkyl, arylalkyl, halogen, haloalkyl or OR 7 ; or R c and R d , together with the carbon atom to which they are attached, optionally form a C 3-6 cycloalkyl ring; R g and R h , at each occurrence, are each independently hydrogen, alkyl, halogen, haloalkyl, hydroxyalkyl, OR 7 , cycloalkylalkyl, heteroaryl, arylalkyl, or heteroarylalkyl; wherein the aryl, cycloalkyl and heteroaryl groups of aryl, cycloalkyl and heteroaryl are each independently unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents independently selected from the group consisting of alkyl and haloalkyl; G 1 is monocyclic aryl or monocyclic heteroaryl; wherein G 1 is unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents selected from the group consisting of alkyl, alkenyl, alkynyl, cyano, haloalkyl, halogen, nitro, oxo, phenyl, N(R 7 ) 2 , N(R 7 )C(O)R 7 , OR 7 , C(O)R 7 , C(O)OR 7 , C(O)N(R 7 ) 2 , SR 7 , SO 2 R 8 , and SO 2 N(R 7 ) 2 ; G 2 and G 3 at each occurrence, are each independently aryl, cycloalkyl, cycloalkenyl, heteroaryl, or heterocycle; wherein G 2 and G 3 at each occurrence are each independently unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents selected from the group consisting of alkyl, alkenyl, alkynyl, cyano, haloalkyl, halogen, nitro, oxo, phenyl, N(R 7 ) 2 , N(R 7 )C(O)R 7 , OR 7 , C(O)R 7 , C(O)OR 7 , C(O)N(R 7 ) 2 , SR 7 , SO 2 R 8 , and SO 2 N(R 7 ) 2 ; R 3 is hydrogen, alkyl, haloalkyl, cycloalkyl, or cycloalkylalkyl; R 4 , R 5 , and R 7 , at each occurrence, are each independently hydrogen, alkyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, or haloalkyl; wherein said aryl, the aryl of arylalkyl and cycloalkyl are independently unsubstituted or substituted with 1, 2 3, 4, or 5 substituents independently selected from the group consisting of alkyl, haloalkyl, and halogen; and R 6 is alkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl, or heterocycle; wherein said aryl, heteroaryl, and heterocycle are independently unsubstituted or substituted with 1, 2 3, 4, or 5 substituents independently selected from the group consisting of alkyl, haloalkyl, and halogen; R 8 is alkyl or haloalkyl.