Patent ID: 8124613

Claim:
A compound represented by formula (I): or a pharmaceutically acceptable salt, hydrate or solvate thereof, wherein: X is an optionally substituted 4 to 7 membered ring comprising 1 or 2 oxygen provided that when X is a 4 membered ring it comprises only one oxygen; n is 0, 1 or 2; R 1 is optionally substituted C 1-10 alkyl, optionally substituted C 2-10 alkenyl, optionally substituted C 2-10 alkynyl, optionally substituted C 3-10 cycloalkyl, optionally substituted C 3-10 cycloalkenyl, or optionally substituted 4 to 7 member heterocycle; R 2 is optionally substituted C 6-12 aryl; R 3 is optionally substituted C 1-10 alkyl, optionally substituted C 2-10 alkenyl, optionally substituted C 2-10 alkynyl; and provided that when —(CH 2 ) n —X is tetrahydrofuran, tetrahydropyran, oxetanyl(CH 2 )—, tetrahydrofuran(CH 2 )— or tetrahydropyran(CH 2 )—, R 3 is isopropyl, then R 1 is not 4,4 difluorocyclohexyl.