Patent ID: 8329689

Claim:
A substituted indole compound which is an ethyl 4-(aminomethyl)-6-aryl(or heterocyclyl)-5-hydroxy-1H-indole-3-carboxylate of the general formula 1.1.1 or an ethyl 9-aryl(or heterocyclyl)-1,2,3,7-tetrahydropyrrolo[3,2-f][1,3]bezoxazine-5-carboxylate of the general formula 1.2.1, or a racemate, optical isomer, or pharmaceutically acceptable salt thereof: wherein R 1 , R 1 4 and R 2 4 are each independently hydrogen, an optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl, or R 1 4 and R 2 4 , together with the N-atom to which they are attached, via R 1 4 and R 2 4 , form optionally substituted azaheterocyclyl or guanidyl; R 2 is hydrogen, an optionally substituted mercapto group, optionally substituted hydroxy group, or optionally substituted amino group, NR 3 4 R 4 4 , wherein R 3 4 and R 4 4 are each independently hydrogen, an optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl, or R 3 4 or R 4 4 together with the N-atom to which they are attached, via R 3 4 and R 4 4 , form optionally substituted azaheterocyclyl or guanidyl; R 7 is hydrogen, an optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl; and Ar is an optionally substituted aryl or an optionally substituted 5- or 6-membered heterocyclyl, wherein the heteroatom is N, O or S.