Patent ID: 8420634

Claim:
A compound of Formula (I), a pharmaceutically acceptable salt, a tautomer and/or solvate thereof: wherein: X is a methylene group (—CH 2 —) Y is a sulphur atom (—S—) Z is an amidine or guanidine group as reported below and where the R1, R2, R′, R″ substituents respectively are: R1 is an atom of hydrogen (—H), fluorine (—F), chlorine (—Cl), a methoxy (—OCH 3 ), trifluoromethoxy (—OCF 3 ), trifluoromethyl (—CF 3 ) or methanesulphonyl (—SO 2 CH 3 ) group; the R1 substituent being able to independently occupy the various positions available on the condensed phenyl; in a compound of formula (I) only one R1 substituent is present; R2 is a C 1 -C 4 alkyl group, an optionally substituted cyclopropyl (—C 3 H 5 ), methylcyclopropyl (—CH 2 C 3 H 5 ), phenyl (-Ph) group or an optionally substituted benzyl (—CH 2 Ph) group, where substituted phenyl or benzyl indicates the presence of no more than two substituents independently occupying the ortho, meta and para positions of the aromatic ring, independently selected from: fluorine (—F), chlorine (—Cl), methyl (—CH 3 ), methoxy (—OCH 3 ), hydroxyl (—OH), trifluoromethyl (—CF 3 ); R′ and R″ are independently selected from: hydrogen (—H) and the groups defined above for R2; provided that when X is a methylene group (—CH 2 —) and Y is a sulphur atom (—S), in the compounds of formula (I) when R1 and R′ are simultaneously a hydrogen atom (—H), R″ is not one of the following groups: 4-methylphenyl, 3-chlorophenyl, or 4-chlorophenyl.