Patent ID: 7919483

Claim:
A method of treating acne vulgaris, comprising administering to a patient suffering from acne vulgaris an amount of a continuous slow release oral dosage form based on body weight of the patient, said continuous slow release oral dosage form comprising: an amount of an oral minocycline antibiotic that provides the patient, upon administration once daily without a loading dose, with 0.7 mg/kg/day to 1.3 mg/kg/day of said oral minocycline antibiotic; and a delivery vehicle having a first lactose monohydrate, a second lactose monohydrate, and a slow dissolving carrier, wherein said first lactose monohydrate is encapsulated by said slow dissolving carrier, wherein said second lactose monohydrate and said slow dissolving carrier are present at a weight ratio of about 0.3 to about 0.5, wherein said delivery vehicle releases said oral minocycline antibiotic at a release rate of: A) about 25 to about 52% within about 1 hour about 53 to about 89% within about 2 hours, and at least about 90% within about 4 hours; or B) about 30 to about 52% within about 1 hour about 53 to about 84% within about 2 hours, and at least about 85% within about 4 hours, wherein said release rate is measured in an aqueous physiological medium.