Patent ID: 7504521

Claim:
A method for preparing a compound having the formula III: wherein R 1 is, CN and CO 2 R 4 ; R 2 is C 1-4 alkyl; R 3 is C 1-4 alkyl, and R 4 is C 1-4 alkyl, or aryl; R 5 is C 1-4 alkyl; and R 14 is selected from the consisting of hydrogen, cyano, alkyl or substituted alkyl, cycloalkyl or substituted cycloalkyl, heterocycle or substituted heterocycle, aryl or substituted aryl and C(═O)OR e ; and R e is alkyl or substituted alkyl, cycloalkyl or substituted cycloalkyl, heterocycle or substituted heterocycle, or aryl or substituted aryl; comprising the steps of: (a) cyclizing a compound of formula IIa or IIb: wherein R 6 is R 8 is H or a halogen; to form a compound of formula Ia or Ib: (b) deprotecting the N* atom in the compound of formula Ia or Ib by reacting the compound of formula Ia or Ib with hydrazine or hydrogen to form a compound of formula III.