Patent ID: 8846659

Claim:
A compound of Formula I where: R 1 is hydrogen, alkyl, alkylCO, (tetrahydropyranyl)CO, ((Ar 2 )alkyl)CO, ((Ar 2 )cycloalkyl)CO, (Ar 2 )CO, CO 2 R 4 , CON(R 5 )(R 6 ), COCO 2 R 4 , or COCON(R 5 )(R 6 ); R 2 is hydrogen or alkyl; R 3 is hydrogen; R 4 is hydrogen, alkyl, or benzyl; R 5 is hydrogen, alkyl, cycloalkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, or alkylCO; R 6 is hydrogen, alkyl, cycloalkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, or alkylCO; or N(R 5 )(R 6 ) taken together is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, or morpholinyl, and is substituted with 0-3 substituents selected from halo and alkyl; Ar 1 is tetrazolyl, triazolyl, oxadiazolyl, thiadiazolyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, furanyl, thienyl, or pyrrolyl; Ar 1 is substituted with 1 benzyl moiety which is further substituted with 0-3 substituents selected from halo and alkyl; and Ar 1 is substituted with 0-2 alkyl substituents; and Ar 2 is tetrazolyl, triazolyl, oxadiazolyl, thiadiazolyl, imidazolyl, oxazolyl, thiazolyl, pyrazolyl, isoxazolyl, isothiazolyl, pyrrolyl, furanyl, thienyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, or hydroxypyridinyl, and is substituted with 0-3 substituents selected from the group consisting of oxo, halo, cyano, benzyl, alkyl, alkoxy, N(R 5 )(R 6 ), CO 2 R 4 , and CON(R 5 )(R 6 ); or a pharmaceutically acceptable salt thereof.