Patent ID: 7862530

Claim:
A method of performing dialysis on a patient in need thereof, wherein the method comprises: a) performing the dialysis in the absence of direct administration of anticoagulant to the patient; and b) performing the dialysis in a dialyzer with a dialysate composition comprising citrate at a concentration ranging from greater than 2.4 to 20 mEq/L, calcium at a concentration ranging from 2.5 to 5 mEq/L, magnesium at a concentration ranging from 0.75 to 2 mEq/L, sodium bicarbonate at a concentration ranging from about 25 to about 40 mEq/L and a buffering anion selected from the group consisting of acetate, in the form of an acetate salt, and lactate, in the form of a lactate salt, or a mixture thereof, at a concentration ranging from about 0.001 to about 4.0 mEq/L.