Patent ID: 7482154

Claim:
An apparatus comprising a transverse electromagnet 400 , at least one region of region of space, a bioreactor positioning system and at least one bioreactor chamber adapted to house at least one biospecimen in said at least one region of space; said biospecimen comprising at least one cell, or at least one fluid and at least one cellular monolayer having a basal surface and a luminal surface, which basal surface may be grown on a substrate; said transverse electromagnet inducing a diamagnetic body force in said at least one biospecimen; said at least one bioreactor chamber being further adapted to sustain said at least one biospecimen in vitro in said at least one region of space by means of biological in vitro support system 200 ; said bioreactor chamber being disposed in said at least one region of space by said bioreactor positioning system and being operationally connected to said biological in vitro support system 200 ; wherein, said at least one region of space contains all points at which a magnetic field-field gradient product of said transverse electromagnet equals or exceeds a threshold value; and, wherein said at least one region of space comprises a region of space between and including a first outer right circular cylinder 441 concentric with a second inner right circular cylinder 442 , said first 441 and second 442 concentric right circular cylinders having a first coplanar base coincident with a first plane of a first circular pole face 435 of a first magnetic pole piece 426 of said transverse electromagnet 400 , said first circular pole face 435 having a pole radius R [ 460 ] at which said magnetic field-field gradient product of said transverse electromagnet 400 has a maximum radial value; and, a second coplanar base coincident with a with a second plane of a second circular pole face 436 of an opposing second magnetic pole piece 427 of said transverse electromagnet 400 , said second circular pole face 436 also having said pole radius R [ 460 ] at which said magnetic field-field gradient product of said transverse electromagnet 400 also has said maximum radial value, said first outer 441 and second inner 442 concentric right cylinders extending between said first circular pole face 435 and said second circular pole face 436 of said transverse electromagnet 400 and centering about a central longitudinal (y-)axis 437 of said transverse electromagnet 400 , said first outer right circular cylinder 441 having a first outer radius R 1 [ 461 ], being greater than said pole radius R [ 460 ], at which first outer radius R 1 [ 461 ] said magnetic field-field gradient product of said transverse electromagnet 400 has a first threshold radial value, and said second inner right circular cylinder 442 having a second inner radius R 2 [ 462 ], being less than said pole radius R [ 460 ], at which second inner radius R 2 [ 462 ] said, of said transverse electromagnet 400 has a second threshold radial value.