Patent ID: 7659099

Claim:
A process for the production of a product by enzymatic treatment of a particulate feed substrate, comprising: treating a feed slurry comprising a particulate, feed substrate with a particulate immobilized enzyme in a bioreactor to produce an effluent slurry comprising effluent product, an effluent particulate feed substrate, and an effluent particulate immobilized enzyme in an effluent slurry, where the particulate immobilized enzyme and the particulate feed substrate have differing particle size distributions or different density distributions; subjecting the effluent slurry to at least one of hydrocloning, screening or continuous centrifuging process to separate the effluent particulate feed substrate from the effluent particulate immobilized enzyme and the effluent product, thereby forming a refined slurry of the effluent particulate immobilized enzyme and the effluent product; and recycling the effluent particulate immobilized enzyme to the bioreactor.