Patent ID: 8598192

Claim:
A compound of the Formula II: wherein: X is C 1-10 alkylene; R A1 and R B1 are taken together to form a fused aryl ring, wherein the aryl ring is unsubstituted or substituted by one R 3 group; R 3 is selected from the group consisting of: —Z—R 4 , —Z—X′—R 4 , and —Z—X′—Y—R 4 ; Y′ is selected from the group consisting of: a bond, —C(O)—, —S(O) 2 —, —S(O) 2 —N(R 8 )—, —C(O)—O—, —C(O)—N(R 8 )—, —C(S)—N(R 8 )—, —C(O)—N(R 8 )—C(O)—, and R 1 is selected from the group consisting of: —R 4 , —X′—R 4 , and —X′—Y—R 4 ; R 2 and R 2a are independently selected from the group consisting of: hydrogen, alkyl, aryl, arylalkylenyl, heteroaryl, heteroarylalkylenyl, heterocyclyl, heterocyclylalkylenyl, and alkyl, aryl, arylalkylenyl, heteroaryl, heteroarylalkylenyl, heterocyclyl, or heterocyclylalkylenyl, substituted by one or more substituents selected from the group consisting of: alkyl, haloalkyl, alkoxy, halogen, and aryl; X′ is selected from the group consisting of alkylene and arylene; Y is selected from the group consisting of: —C(R 6 )—, —N(R 8 )-Q-, and —C(R 6 )—N(R 8 )—; Z is a bond; R 4 is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, and aryl, wherein the alkyl, alkenyl, alkynyl, and aryl groups can be unsubstituted or substituted by one or more substituents independently selected from the group consisting of alkyl, alkoxy, hydroxyalkyl, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, mercapto, cyano, aryl, amino, alkylamino, and dialkylamino; R 6 is ═O; R 7 is C 2-7 alkylene; R 8 is selected from the group consisting of hydrogen and C 1-10 alkyl; R 10 is C 3-8 alkylene; Q is selected from the group consisting of a bond, —C(R 6 )—, —S(O) 2 —, and —C(R 6 )—N(R 8 )—W—; and W is selected from the group consisting of a bond, —C(O)—, and —S(O) 2 —; or a pharmaceutically acceptable salt thereof.