Patent ID: 7312086

Claim:
A method of diagnosing colon adenocarcinoma in a patient comprising: a) determining the expression levels of a polypeptide of SEQ ID NO:2, or a fragment thereof, in a normal colon sample and a colon test sample, wherein the expression levels are determined by measuring the protein level of an isolated polypeptide selected from the group consisting of an isolated polypeptide comprising SEQ ID NO:2, an isolated polypeptide comprising at least 7 contiguous amino acids of SEQ ID NO:2, an isolated polypeptide comprising amino acids 1 to 337 of SEQ ID NO:2, an isolated polypeptide comprising amino acids 2 to 337 of SEQ ID NO:2, and an isolated polypeptide consisting of the polypeptide encoded by the HGPRBMY23 cDNA clone contained in ATCC Deposit No. PTA-2966; and b) comparing the expression level of said polypeptide from the colon test sample with the expression level of said polypeptide from the normal colon sample, wherein an elevated expression level of said polypeptide in the test sample relative to the expression level of said polypeptide in the normal sample is indicative of colon adenocarcinoma.