Patent ID: 8753309

Claim:
A device comprising: a quasi-planar substrate; and two or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein at least two of the two or more laterally-mobile effector molecule types are sequentially placed to interact with one or more cell types; one or more sensors configured to detect at least one aspect of an interaction between the at least one of the two or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the two or more laterally-mobile effector molecule types and the quasi-planar substrate, and wherein the controller is configured to responsively control the interaction between the at least one of the two or more laterally-mobile effector molecule types and the one or more cell types to initiate activation, maturation, differentiation, anergy induction, antigen loading, electroporation, or transduction in the one or more cell types.