Patent ID: 8344007

Claim:
A cantharimide compound, comprising the background of formula (1): wherein, R 1 , R 2 , R 3 , and R 4 are independently selected from the group consisting of H, C(O)OR 5 , C(O)R 6 , C(O)NR 7 R 8 , NR 9 C(O)R 10 , N—R 11 R 12 , O—R 13 , S—R 14 , P(O)(OR 15 )(OR 16 ), As(O)(OR 17 )(OR 18 ), SO 2 R 19 , SO 3 R 20 , and B(OR 21 ), wherein the R 1 to R 4 are not all hydrogen with the proviso that R 3 is not hydrogen; wherein the X 1 to X 4 are carbon; and wherein the Y 1 , Y 2 and R 5 to R 21 are independently selected from the group consisting of hydrogen, C 1-12 -alkyl, aryl, heteroaryl, and a bioactive polymer comprising: (i) a polymer moiety from 2 to 300 monomer units; and (ii) a terminal moiety connected to the polymer moiety at the ω-position, provided that the cantharimide compound is neither and a pharmaceutically acceptable salt, solvate or hydrate thereof.