Patent ID: 8466164

Claim:
A compound having the formula: wherein R represents H, alkylthio, alkylamino, cycloalkylthio, cycloalkylamino, S(CH 2 ) n OH, S(CH 2 ) n NH 2 , NH(CH 2 ) n OH, or NH(CH 2 ) n NH 2 ; R 1 represents NH—R 6 or N(R 6 ) 2 ; R 6 represents an aryl with the formula: in which X and Y are independently C or N; R 6 ′, R 7 ′, R 8 ′, R 9 ′, R 10 ′ are independently H, —C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, aryl substituted groups, halo, haloalkyl, OCH 3 , NO 2 , CN, CONH 2 , CONH—C 1-6 alkyl, CON(C 1-6 alkyl) 2 , NH 2 , NH—C 1-6 alkyl, N(C 1-6 alkyl) 2 , NHC(O)alkyl, NHSO 2 —C 1-6 alkyl, SO 2 NH 2 , SO 2 NHC 1-6 alkyl, SO 2 N(C 1-6 alkyl) 2 , OZ′ or SZ′ where Z′ is H, or alkyl, aryl or aralkyl substituted group, m is comprised between 0 and 4, provided that when X and Y are C, at least one of R 6 ′, R 7 ′, R 8 ′, R 9 ′, and R 10 ′ is C 1-6 alkyl, OCH 3 , or halogen; R 2 represents H; R 4 represents wherein wherein R 21 ′, R 22 ′, R 23 ′, R 24 ′, R 25 ′ are independently H, or halo; and R 5 represents Cl, Br, OH, H, CH 3 .