Patent ID: 7507762

Claim:
A method of treating breast or prostate carcinoma in a mammal suffering therefrom, comprising administering to a mammal in need of such treatment an effective amount of a compound of Formula II: or a pharmaceutically acceptable salt thereof, wherein: X is O; Y is CN; or Z is NH 2 ; R 1 , R 3 and R 4 are independently hydrogen, halo, haloalkyl, aryl, fused aryl, carbocyclic, a heterocyclic group, a heteroaryl group, C 1-10 alkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkyl, heteroarylalkenyl, heteroarylalkynyl, carbocycloalkyl, heterocycloalkyl, hydroxyalkyl, aminoalkyl, carboxyalkyl, nitro, amino, cyano, acylamido, hydroxy, thiol, acyloxy, azido, alkoxy, carboxy, carbonylamido or alkylthiol; R 2 is NR 8 R 9 , wherein R 8 and R 9 are independently H or C 1-10 alkyl; R 5 is hydrogen or C 1-10 alkyl; and A is optionally substituted and is phenyl.