Patent ID: 7667054

Claim:
A taxane compound having the following formula (I): wherein Z=H or a radical of formula II; R 1 is a linker; R 3 is a linker or an optionally substituted aryl or heterocyclic radical, alkyl having from 1 to 10 carbon atoms, alkenyl or alkynyl having from 2 to 10 carbon atoms, cycloalkyl or cycloalkenyl having from 3 to 10 carbon atoms; R 4 is a linker, H, a hydroxy radical, an alkoxy, an alkenyloxy, an optionally substituted alkanoyloxy, aroyloxy, alkenoyloxy, alkynoyloxy, cycloalkanoyloxy, alkoxyacetyl, alkylthioacetyl, alkyloxycarbonyloxy, cycloalkyloxy, cycloalkenyloxy, carbamoyloxy, alkylcarbamoyloxy, or dialkylcarbamoyloxy, a heterocyclic or aryl ether, ester or carbamate, or, a linear, branched, or cyclic alkyl or alkenyl ester or ether having from 1 to 10 carbon atoms or a carbamate of the formula —OCOX, wherein X is a nitrogen-containing heterocycle, or a carbamate of the formula —OCONR 9 R 10 , wherein R 9 and R 10 are the same or different and are H, linear, branched, or cyclic alkyl having from 1 to 10 atoms or simple or substituted aryl having from 1 to 10 carbon atoms; R 5 and R together form a bond to form a cyclic ether, or R 7 and R together form a bond to form a cyclic ether; provided that when R 5 and R form a bond, then R 7 is H, and provided that when R 7 and R form a bond then R 5 is H; R 6 is H; and R 8 is optionally substituted aryl or a heterocyclic radical.