Patent ID: 8124624

Claim:
A substituted sulfonamide compound corresponding to formula (I): wherein m represents 0, 1 or 2; n represents 1 or 2; o represents 0, 1 or 2; p represents 0, 1 or 2; q represents 0, 1, 2, 3 or 4; Q represents a single bond, —O— or —CH 2 —; R 1 represents aryl or heteroaryl, or aryl or heteroaryl bonded via a C 1-3 -alkylene group; R 2 represents H, C 1-16 -alkyl, C 3-8 -cycloalkyl, bicyclic 8- to 12-membered carbocyclyl, CH(aryl) 2 , aryl or heteroaryl; or C 3-8 -cycloalkyl, bicyclic 8- to 12-membered carbocyclyl, CH(aryl) 2 , aryl or heteroaryl bonded via a C 1-6 -alkylene group, C 2-6 -alkenylene group or C 2-6 -alkynylene group; and R 3 represents H, C 1-6 -alkyl, aryl or heteroaryl; or aryl or heteroaryl bonded via a C 1-6 -alkylene group, C 2-6 -alkenylene group or C 2-6 -alkynylene group; or R 2 and R 3 together with the group —N—(CH—)— joining them, form a 4-, 5-, 6- or 7-membered heterocycle, which optionally may be fused to an aryl or heteroaryl group, wherein said heterocycle may be saturated or mono- or polyunsaturated but not aromatic, and optionally may contain, in addition to the N heteroatom to which R 2 is bonded, one or more further heteroatoms or heteroatom groups selected from the group consisting of N, NR 7 , O, S, S═O and S(═O) 2 ; wherein R 7 denotes H, C 1-6 -alkyl, —C(═O)—R 8 , C 3-8 -cycloalkyl, aryl, heteroaryl, or C 3-8 -cycloalkyl, aryl or heteroaryl bonded via a C 1-3 -alkylene group, and R 8 denotes C 1-6 -alkyl, C 3-8 -cycloalkyl, aryl, heteroaryl, or C 3-8 -cycloalkyl, aryl or heteroaryl bonded via a C 1-3 -alkylene group; R 4 denotes aryl, heteroaryl, or aryl or heteroaryl bonded via a C 1-6 -alkylene group; R 5 and R 6 each independently denote H, C 1-6 -alkyl, C 3-8 -cycloalkyl, or C 3-8 -cycloalkyl bonded via a C 1-3 -alkylene group, wherein R 5 and R 6 do not simultaneously represent H; or R 5 and R 6 together represent a substituted or unsubstituted 5- or 6-membered heteroaryl which optionally may contain, in addition to the N atom to which R 5 and R 6 are bonded, at least one further heteroatom selected from the group consisting of N, O and S, or R 5 and R 6 together represent a group selected from —(CH 2 ) d — and —(CH 2 ) e —X—(CH 2 ) f —, wherein d denotes 2, 3, 4, 5 or 6, e and f each independently denote 1, 2 or 3, with the proviso that e+f is not greater than 5; X denotes NR 12 , CF 2 , O, S, S(═O) or S(═O) 2 ; wherein R 12 denotes H, C 1-6 -alkyl, C 3-8 -cycloalkyl, aryl, heteroaryl, or C 3-8 -cycloalkyl, aryl or heteroaryl bonded via a C 1-3 -alkylene group; and wherein said C 1-6 -alkyl, C 1-6 -alkylene, C 2-6 -alkenylene, C 2-6 -alkynylene, C 3-8 -cycloalkyl, C 3-8 -heterocycloalkyl, bicyclic 8- to 12-membered carbocyclyl, aryl and heteroaryl may each be unsubstituted or mono- or poly-substituted by identical or different substituents, and said C 1-6 -alkyl, C 1-6 -alkylene, C 2-6 -alkenylene and C 2-6 -alkynylene may each be branched or unbranched; or a physiologically acceptable salt thereof.