Patent ID: 7732196

Claim:
A polynucleotide encoding two engineered zinc finger proteins, wherein the first zinc finger protein comprises six zinc fingers and the amino acid sequence of the recognition region of each of the zinc fingers is as follows: F1: RSDALSR (SEQ ID NO: 14) F2: QSGDLTR (SEQ ID NO: 15) F3: QSGDLTR (SEQ ID NO: 15) F4: TSGHLSR (SEQ ID NO: 16) F5: RSDHLSN (SEQ ID NO: 17) F6: QSATRIT; (SEQ ID NO: 18) and wherein the second zinc finger protein comprises three zinc fingers and the amino acid sequence of the recognition region of each of the zinc fingers is as follows: F1: DRSNLTR (SEQ ID NO: 83) F2: TSGHLSR (SEQ ID NO: 16) F3: RSDHLSR (SEQ ID NO: 84).