Patent ID: 8557797

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein R 1 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, phenyl which is optionally substituted, 5- or 6-membered monocyclic heteroaryl which is optionally substituted, or a radical of formula (II) wherein n is 1 or 2, and R 3 and R 4 are independently H or C 1 -C 6 alkyl, or R 3 and R 4 taken together with the nitrogen to which they are attached form a 6-membered heterocyclic ring optionally comprising a further heteroatom selected from N and O; Y is —O— or —S(O) p — wherein p is 0, 1, or 2; A is an optionally substituted divalent arylene radical, a monocyclic heteroaryl radical, a bicyclic heteroarylene radical, a C 3 -C 6 divalent cycloalkylene radical having 5 or 6 ring atoms, or a piperidinylene radical wherein the ring nitrogen is linked to R 2 NHC(═O)W—; W is a bond, —NH—or —C(R A )(R B ), wherein R A and R B are independently H, methyl, ethyl, amino, hydroxyl, or halo; and R 2 is a radical of formula (IIIA), (IIIB), or (IIIC): wherein m is 0 or 1, q is 0, 1, 2, or 3, T is —N═ or —CH═, R 5 is H or F, R 7 is —CH 3 , —C 2 H 5 , —CH 2 OH, —CH 2 SCH 3 , —SCH 3 , or - SC 2 H 5 , R 8 is —CH 3 or —C 2 H 5 , and each occurrence of R 6 is independently H, C 1 -C 6 , hydroxyl, or halo; or a single occurrence or R 6 is a radical of formula (IVA), (IVB), or (IVC) while any other occurrence of R 6 is independently H, C 1 -C 6 alkyl, hydroxyl or halo; and wherein, in R 6 , R 61a and R 61b are H, alkyl, or R 61a and R 61b are optionally joined together with the nitrogen to which they are attached to form a heterocyclic ring optionally comprising a further heteroatom selected from N and O.