Patent ID: 7235237

Claim:
A method to treat a vascular disease resulting from nitric oxide insufficiency in a patient comprising administering to the patient a therapeutically effective amount of at least one antioxidant enzyme, and at least one compound that donates, transfers, or releases nitric oxide, or induces the production of endogenous nitric oxide, or endothelium-derived relaxing factor, or is a substrate for nitric oxide synthase, or a pharmaceutically acceptable salt thereof, wherein the antioxidant enzyme is superoxide dismutase, catalase, glutathione peroxidase, or a mixture thereof and the vascular disease resulting from nitric oxide insufficiency is a disease resulting from oxidative stress and wherein the at least one antioxidant enzyme, and the at least one compound that donates, transfers, or releases nitric oxide, or induces the production of endogenous nitric oxide, or endothelium-derived relaxing factor, or is a substrate for nitric oxide synthase are administered as components of the same composition, or are administered as separate components at about the same time.