Patent ID: 8865706

Claim:
A compound of Formula I wherein R 1 is hydrogen or methyl, wherein said methyl is optionally substituted with one to three fluoro; R 2 is a 5- to 10-membered heteroaryl, having one to four heteroatoms independently selected from N, O or S, wherein at least one of the heteroatoms is N and wherein said N is optionally substituted with R 4 ; and wherein said 5- to 10-membered heteroaryl is optionally substituted on carbon with one to three R 3 ; R 3 at each occurrence is independently selected from the group consisting of halogen, hydroxy, cyano, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkoxy-C 1-6 alkyl, C 3-6 cycloalkoxy, C 3-6 cycloalkoxy-(CR 5a R 5b ) m —, C 3-6 cycloalkyl-(CR 5a R 5b ) n —O—, —(CR 5a R 5b ) m —C 3-6 cycloalkyl or —(CR 5a R 5b ) m -(4- to 6-membered heterocycloalkyl); wherein said C 1-6 alkyl, C 1-6 alkoxy or C 1-6 alkoxy-C 1-6 alkyl are each optionally substituted with one to three fluoro and wherein said C 3-6 cycloalkyl, C 3-6 cycloalkoxy and (4- to 6-membered heterocycloalkyl) moieties are optionally substituted with one to three substituents independently selected from the group consisting of fluoro, methyl, fluoromethyl, difluoromethyl or trifluoromethyl; R 4 is hydrogen, C 1-6 alkyl, —(CR 5a R 5b ) m —C 3-6 cycloalkyl or —(CR 5a R 5b ) m -(4- to 6-membered heterocycloalkyl); wherein said C 1-6 alkyl, C 3-6 cycloalkyl and -(4- to 6-membered heterocycloalkyl) moieties are each optionally substituted with one to three substituents independently selected from fluoro, methyl, trifluoromethyl, methoxy or trifluoromethoxy; R 5a and R 5b are independently hydrogen, methyl, fluoromethyl, difluoromethyl, trifluoromethyl or methoxy; m at each occurrence is independently 0, 1 or 2; and n is 1, 2 or 3; or a tautomer thereof or a pharmaceutically acceptable salt of said compound or tautomer.