Patent ID: 7722857

Claim:
An immunoadjuvant comprising one kind or two or more kinds of immunostimulating substances carried by each of two or more kinds of different microparticle immunostimulating substance carriers, which at least comprises a combination of (a) microparticle calcium phosphate having a size phagocytizable by cells, and (b) a precipitate of a soluble protein and a mucopolysaccharide formed by coacervation as said microparticle immunostimulating substance carriers, wherein the microparticle calcium phosphate of (a) is microparticle calcium phosphate having a Ca/P molar ratio of 1.3 or higher, containing 1 to 15% by weight of carbonate groups CO 3 2− , and having a degree of crystallinity, in an XRD spectrum obtained with a CuKα ray, not lower than a degree of crystallinity defined by appearance of broad peaks having centers at 2θ values of 26°, 32° and 34° and appearance of a shoulder with a Miller index of 300 at 33°, and not higher than a degree of crystallinity defined by appearance of peaks or shoulders having centers at 26°, 28.1°, 29°, 32°, 33° and 34° and by separation of peaks with Miller indexes of 211 and 112.