Patent ID: 8211911

Claim:
A compound of formula I Wherein Ring Q is a bicyclic aryl or a bicyclic heterocyclyl moiety, selected from: R is each independently selected from H, halogen, halogeno-lower alkyl, lower alkyl, hydroxy, lower alkoxy, lower alkoxyalkoxy, lower alkenyl, lower alkynyl, amino, alkylamino, alkoxyamino, cycloalkyl, cycloalkenyl, aryl or heterocyclyl; R 1 is selected from H, halogen, halogeno-lower alkyl, lower alkyl, hydroxy, lower alkoxy, lower alkoxyalkoxy, lower alkenyl, or lower alkynyl; A is selected from direct bond of —N(R′)—; B is selected from direct bond, O, —N(R′)—, —C(═Z)—, —C(═Z)N(R′)—, lower alkylenyl-C(═Z)— or lower alkylenyl-C(═Z)N(R′)—; Z is selected from O or S; a is selected from 1, 2, 3, 4 or 5; b, c and d are each independently selected from 1, 2, or 3; G is selected from C—R, C—(CN) or N; R′ and R″ are not presented, when X and Y are selected from (i) X combines Y to be an oxygen or methylene, (ii) X is hydrogen, Y is hydrogen, (iii) X is hydrogen, Y is hydroxy or its optical isomer; R′ and R″ are each independently selected from halogeno-lower alkyl, lower alkyl, lower alkoxy, hydroxy, lower alkylhydroxy, when X and Y are selected from (i) X is hydrogen, Y is O, S or its optical isomer, (ii) X and Y are both O or S, or (iii) X is O and Y is S; optionally R′ and R″ combine to form a 5 to 7 membered ring with X, Y and the said ring can be unsubstituted or substituted independently by up to three substituents, or a pharmaceutically acceptable salt thereof.