Patent ID: 8187810

Claim:
A method of diagnosing overactive bladder (OAB) in a human patient, the method comprising: isolating ribonucleic acid (RNA) from peripheral blood mononuclear cells (PBMC) of the patient and from the PBMC of at least one appropriately matched control subject; converting the RNA to complementary RNA (cRNA); and subjecting the cRNA to microarray analysis to determine cRNA levels of at least one gene selected from the group consisting of platelet-derived growth factor (PDGF), microfibrillar-associated protein 3-like (MFAP3L), and tropomyosin 1 (TPM1), wherein a difference in the cRNA levels of said at least one gene between the patient's cRNA and the cRNA of the at least one appropriately matched control subject indicates that the patient be diagnosed with OAB.