Patent ID: 7312235

Claim:
A compound of formula Ia: wherein: Ar1 is independently selected from the group consisting of: each R is independently selected from the group consisting of Cl, OMe, NHMe, —NMe 2 , —OCH 2 CH 2 OMe, —OCH 2 CH 2 NMe 2 , —SMe, —SO 2 Me, L1 is a direct link, —CONH, —CH 2 NH, or —NHCO—; L2 is —CONH, or —NHCO; Ar3 is Ar2 is independently selected from the group consisting of: Ar2 may be optionally substituted with 0-3 R 1d group; each R 1d is independently selected from the group consisting of: H, —Me, —F, —Cl, —Br, I, —CH 3 , —CF 3 , —CN, —CO 2 H, —CO 2 Me, —CO 2 Et, —CONH 2 , —CONHMe, —CONMe 2 , —CH 2 NMe 2 , —COMe, —CH 2 COOH, —OCH 3 , —OCF 3 , —OCH 2 F, —OCHF 2 , —OCH 2 CF 3 , —OCF 2 CF 3 , —OCH 2 CO 2 H, —OCH 2 CO 2 Me, —OCH 2 CO 2 Et, —OCH 2 CONH 2 , —OCH 2 CONMe 2 , —OCH 2 CONHMe, —OCH 2 CH 2 OMe, —OCH 2 CH 2 NHMe, —OCH 2 CH 2 NMe 2 , —SCH 3 , —SO 2 NH 2 , —SO 2 CH 3 , —SO 2 NMe 2 , —NMe 2 , —NHCH 2 NMe 2 , —N(CH 2 CH 2 OH) 2 , —N(CH 2 CH 2 OMe) 2 , —NHCH 2 CO 2 H, —NHCH 2 CO 2 Et, —NHCH 2 CO 2 Et, —NHCH 2 CONH 2 , —NHCH 2 CONMe 2 , —N(Me)CH 2 CH 2 NMe 2 , —N(Me)CH 2 CH 2 OMe, —NHCH 2 CH 2 OMe, —NHCH 2 CH 2 OMe; A is independently selected from the group consisting of: and all pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrugs derivatives thereof.