Patent ID: 8137391

Claim:
A high viscosity composition for application onto extremities of a mammal, which is heatable above a body temperature of the mammal and coolable below 0° C. within a predetermined termperature interval and which comprises: a polyoxyethylene-polyoxypropylene-block copolymer having the structural formula HO(C 2 H 4 O) a (C 3 H 6 O) b (C 2 H 4 O) a H; an additional polymer; and a dispersion medium, comprising at least one freezing point depressing dispersant and at least one freezing point non-depressing dispersant; wherein said polyoxyethylene-polvoxypropylene-block copolymer is poloxamer 407 having an average molecular weight of about 12600 and wherein a is 101 and b is 56, said poloxamer 407 being included in an amount of 10-25% by weight of the composition, said additional polymer is polyvinylpyrrolidone having an average molecular weight of about 1 million and being included in an amount of 5-20% by weight of the composition, said freezing point depressing dispersant is selected from the group consisting of propylene glycol, ethylene glycol, butylene glycol and glycerol, said freezing point non-depressing dispersant is selected from the group consisting of water and a higher alcohol having a boiling point above 100° C. and mixtures thereof, and said freezing point depressing dispersant constitutes 20-90% of the dispersion medium and the freezing point non-depressing dispersant constitutes 80-10% of the dispersion medium, and wherein the composition also comprises a strong electrolyte selected from the group consisting of sodium, potassium, calcium and magnesium chloride, said electrolyte being included in an amount of 2-7% by weight of the composition.