Patent ID: 7968711

Claim:
An ophthalmic solution comprising a therapeutically effective amount of a compound of formula I′ wherein R is selected from the group consisting of H, halogen; and C 1-5 alkyl; R 1 is selected from the group consisting of H or halogen; R 2 is independently selected from the group consisting of H, C 1-5 alkyl, halogen, XC 1-5 alkyl, C 1-5 alkylOR 13 , C 1-5 alkylN(R 13 ) 2 , N(R 13 ) 2 , XC 1-5 alkylN(R 13 ) 2 and XC 1-5 alkylOR 13 ; X is O or S(O) n ; n is 0 or an integer of from 1 to 2; Y is selected from the group consisting of keto and hydroxyl; Y 1 is selected from the group consisting of hydroxyl, halogen and C 1 -C 5 alkyl; and Q is a halogen-substituted phenyl, R 13 is selected from the group consisting of H, C 1-5 alkyl and C 3-8 cyclic alkyl.