Patent ID: 7652054

Claim:
A compound of formula I, wherein X 1 represents —C(R 1 )— and X 2 represents —N—; X 3 represents —C(R 2 )—; X 4 represents —C(R 3 )—; R 1 represents H, and R 2 and R 3 independently represent H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkoxy-C 1-6 -alkyl or halo; Y 1 , Y 2 , Y 3 , and Y 4 independently represent —CH— or —CF—; Z 1 , represents S; Z 2 represents —CH— or —N—; R 4 represents —S(O) 2 N(H)C(O)R 6 , —S(O) 2 N(H)S(O) 2 R 6 , or —C(O)N(H)S(O) 2 R 6 , R 5 represents C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkoxy-C 1-6 -alkyl or di-C 1-3 -alkylamino-C 1-4 -alkyl; R 6 represents C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkoxy-C 1-6 -alkyl, and C 1-3 alkoxy-C 1-6 -alkoxy, C 1-6 alkylamino or di-C 1-6 alkylamino or a pharmaceutically-acceptable salt thereof.