Patent ID: 8129196

Claim:
A microarray hybridization chamber for parallel loading of samples comprising: a sample loading array comprising a plurality of micro-channels having a first open end on a first side of the micro-channel array and a second open end on a second side of the micro-channel array, said first end and second end defining a channel in fluid communication with the first side of the micro-channel array and the second side of the channel area, each channel having a longitudinal axis passing through its center and defining the center of the channel; a microarray comprising a plurality of sub-arrays; the microarray and the loading array being adapted to define a hybridization chamber wherein each of the plurality of sub-arrays comprises multiple features; a membrane in contact with the second side of the micro-channel array to close the second end of the micro-channels and to allow for the selective passing of liquids and molecules through the membrane and through the micro-channels; and a gasket, placed between the first side of the micro-channel array and the microarray so as to provide a hybridization chamber, the center of each channel aligned with the center of each sub-array, the first open ends of the micro-channels facing the sub-arrays of the microarray.