Patent ID: 7820702

Claim:
A compound having the formula or a pharmaceutically acceptable salt thereof, wherein R 1 is hydrogen (H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, arylalkyl or substituted arylalkyl, CO 2 R 4a , CONR 4a R 4b or CH 2 OR 4a ; R 2 is OR 3 , SR 3 , halo, NHR 3 , NHCOR 4c 1 , NHCO 2 R 4c 1 , NHCONR 4c R 4d or NHSO 2 R 4c ; R 3 in each functional group is independently hydrogen (H), alkyl or substituted alkyl, CHF 2 , CF 3 or COR 4e ; R 4 , R 4a , R 4b , R 4c , R 4c 1 , R 4d , R 4e , R 4f , and R 4g , in each functional group are the same or different and are each independently hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; R 5 and R 5 ′ are the same or different and are each independently selected from the group consisting of hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, and heteroaryl or substituted heteroaryl, wherein at least one of R 5 and R 5 ′ is hydrogen; or, R 5 and R 5 ′ taken together form a double bond with oxygen (O), sulfur (S), NR 7 or CR 7 R 7 ′; R 7 and R 7 ′ in each functional group are the same or different and are each independently hydrogen(H), OR 4 , alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; G is an aryl, heterocyclo or heteroaryl group, wherein said group is mono- or polycyclic, and which is optionally substituted with one or more substituents selected from the group consisting of hydrogen, halo, CN, CF 3 , OR 4f , CO 2 R 4f , NR 4f R 4g , CONR 4f R 4g , CH 2 OR 4f , alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; n is an integer of 1 or 2; and m is an integer of 1 or 2.