Patent ID: 8158063

Claim:
A biosensor package structure with a micro-fluidic channel, the biosensor package structure comprising: an inflexible substrate having a first surface, a second surface, and an opening, wherein a circuit is formed on the first surface; a biochip attached on the first surface and defined with a bio-sensing area totally exposed to the opening; an adhesive that affixes the biochip to the first surface; and a cover having a cavity, a sample inlet, and a sample outlet, and the cover is attached on the second surface to cover the opening so that the cavity is in communication with the opening to form a micro-fluidic channel and the sample inlet and the sample outlet are both in communication with the cavity and the opening so that a biomedical sample is introduced into the micro-fluidic channel through the sample inlet and then pass through the bio-sensing area; wherein the biochip has a ball grid array electrically connected with the circuit on the inflexible substrate, with the ball grid array placed on the same side as the bio-sensing area; and wherein the adhesive is filled between the biochip and the first surface by the underfill packaging process to surround the ball grid array.