Patent ID: 6905669

Claim:
A method for treating a patient having a cancer with a combination therapy, comprising: administering to said patient a therapeutically effective amount of a DNA methylation inhibitor that is 5-azacytidine or decitabine at a dose ranging from 1 to 50 mg/M 2 per day, in combination with a therapeutically effective amount of a histone deacetylase inhibitor selected from the group consisting of trichostatin A, suberoylanilide hydroxamic acid, oxamflatin, suberic bishydroxamic acid, m-carboxy-cinnamic acid bishydroxamic acid, pyroxamide, trapoxin A, apicidin, depsipeptide, N-(2-aminophenyl)-4-[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]benzamide, butyric acid, phenylbutyrate and arginine butyrate.