Patent ID: 8273776

Claim:
A compound represented by Formula I, its individual enantiomers, individual diastereoisomers, individual tautomers or a pharmaceutically acceptable salt thereof, R 1 is C 1-10 alkyl, C 3-10 cycloalkyl, —OC 1-10 alkyl, —OH, halogen, aryl, heterocycle; R 2 is H, C 1-10 alkyl, C 3-10 cycloalkyl, —OC 1-10 alkyl, —OH, halogen or nitrile; X is H, halogen, or Z; Q is —(CH 2 ) n N(C 2-10 )alkylene-, —O(C 2-10 )alkylene- or —S(C 2-10 )alkylene-; n is 0, 1, 2, 3, 4 or 5; and Z is COOR, SO 2 NH 2 , OPO 3 H 2 or —P(O)(R)OH; and R is H, C 1-10 alkyl, C 3-10 cycloalkyl.