Patent ID: 7700336

Claim:
A lecithinized human superoxide dismutase composition comprising a lecithinized human superoxide dismutase A and a lecithinized human superoxide dismutase B, wherein each lecithinized human superoxide dismutase has at least one amino group in a copper-and/or zinc-coordinated human superoxide dismutase substituted by a hydroxyethylthio group at the cysteine at position 111, and each lecithinized human superoxide dismutase has at least one lecithin moiety represented by the following formula (I): wherein R is a C 8-30 alkyl group, and n is an integer of from 2 to 10, wherein the lecithinized human superoxide dismutase (A) has m number of amino groups substituted with the lecithin moieties wherein m is an integer of from 1 to 4, and the lecithinized human superoxide dismutase (A) consists of from 25 to 40 mol % of a lecithinized superoxide dismutase (a1) wherein m=1, from 35 to 50 mol % of a lecithinized superoxide dismutase (a2) wherein m=2, from 10 to 20 mol % of a lecithinized superoxide dismutase (a3) wherein m=3 and from 5 to 15 mol % of a lecithinized superoxide dismutase (a4) wherein m=4, and wherein the lecithinized human superoxide dismutase B has 5-12 amino groups substituted with lecithin moieties represented by the formula (I).