Patent ID: 8101754

Claim:
A triazole compound of formula wherein n is 1 or 2; Ar is a C-bound 1,2,4-triazol radical which carries a radical R 1 on the remaining carbon atom and a radical R 1a on one of the nitrogen atoms; R 1 is hydrogen, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 4 alkoxymethyl, fluorinated C 1 -C 6 alkyl, fluorinated C 3 -C 6 cycloalkyl, fluorinated C 1 -C 4 alkoxymethyl, phenyl or 5- or 6-membered heteroaryl, wherein phenyl and heteroaryl may be unsubstituted or substituted by 1, 2, 3 or 4 radicals R a selected independently of each other from halogen, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 4 alkoxy-C 1 -C 4 -alkyl, fluorinated C 1 -C 4 alkyl, CN, NO 2 , OR 3 , NR 3 R 4 , C(O)NR 3 R 4 , O—C(O)NR 3 R 4 , SO 2 NR 3 R 4 , COOR 5 , SR 6 , SOR 6 , SO 2 R 6 , O—C(O)R 7 , COR 7 or C 3 -C 5 cycloalkylmethyl, wherein phenyl and heteroaryl may also carry a phenyl group or an aromatic 5- or 6-membered C-bound heteroaromatic radical, comprising 1 nitrogen atom as ring member and 0, 1, 2 or 3 further heteroatoms, independently of each other, selected from O, S and N, wherein the last two mentioned radicals may carry 1, 2, 3 or 4 of the aforementioned radicals R a —; R 1a is hydrogen or C 1 -C 4 alkyl; R 2 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, fluorinated C 1 -C 6 alkyl or fluorinated C 3 -C 6 cycloalkyl; R 3 , R 4 , R 5 , R 6 , and R 7 independent of each other are H, C 1 -C 6 alkyl, optionally substituted with OH, C 1 -C 4 alkoxy or phenyl, C 1 -C 4 haloalkyl or phenyl, which may carry 1, 2 or 3 radicals selected from the group consisting of C 1 -C 6 alkyl, C 1 -C 6 alkoxy, NR 3a R 4a , CN, C 1 -C 2 fluoroalkyl and halogen, wherein R 3a and R 4a are independent of each other H, C 1 -C 6 alkyl, optionally substituted with OH, C 1 -C 4 alkoxy or phenyl, C 1 -C 4 haloalkyl or phenyl, which may carry 1, 2 or 3 radicals selected from the group consisting of C 1 -C 6 alkyl, C 1 -C 6 alkoxy, amino, NH(C 1 -C 4 alkyl) and N(C 1 -C 4 alkyl) 2 ; R 4 may also be a radical COR 8 , wherein R 8 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy or phenyl, which may carry 1, 2 or 3 radicals selected from the group consisting of C 1 -C 6 alkyl, C 1 -C 6 alkoxy, NR 3 R 4 , CN, C 1 -C 2 fluoroalkyl and halogen, R 3 and R 4 may together with the nitrogen atom to which they are bound form a N-bound 5 or 6 membered saturated heterocycle, which may comprise an oxygen atom or an additional nitrogen atom as a ring member and which may carry 1, 2, 3 or 4 C 1 -C 6 alkyl groups, or physiologically tolerated acid addition salts thereof.