Patent ID: 6949559

Claim:
A compound of the following formula: wherein: R 1 are the same or different and independently selected from the group consisting of: H; C 1 -C 6 -straight chain alkyl; C 2 -C 6 -straight alkenyl chain; C 3 -C 6 -branched alkyl chain; C 3 -C 6 -branched alkenyl chain; C 3 -C 7 -cycloalkyl; CH 2 —(C 3 -C 7 -cycloalkyl); CH 2 CF 3 ; CH 2 CH 2 CF 3 ; and CH(CF 3 ) 2 ; Q=N and D=X=CH; V=NH; O; S; or CH 2 ; R 2 =phenyl; substituted phenyl, wherein the substituents (1-2 in number) are in any position and are independently selected from the group consisting of R 1 , OR 1 , SR 1 , S(O)R 1 , S(O 2 )R 1 , NHR 1 , NO 2 , OC(O)CH 3 , NHC(O)CH 3 , F, Cl, Br, CF 3 , C(O)R 1 , C(O)NHR 1 , phenyl, and C(O)NHCHR 1 CH 2 OH; 1-naphthyl; 2-naphthyl; heterocycles selected from the group consisting of: 2-pyridyl; 3-pyridyl; 4-pyridyl; 2-pyrimidyl; 4-pyrimidyl; 5-pyrimidyl; thiophene-2-yl; thiophene-3-yl; 2-furanyl; 3-furanyl; oxazol-2-yl; oxazol-4-yl; oxazol-5-yl; thiazol-2-yl; thiazol-4-yl; thiazol-5-yl; imidazol-2-yl; imidazol-4-yl; pyrazol-3-yl; pyrazol-4-yl; isoxazol-3-yl; isoxazol-4-yl; isoxazol-5-yl; isothiazol-3-yl; isothiazol-4-yl; isothiazol-5-yl; 1,3,4-thiadiazol-2-yl; benzo[b]furan-2-yl; benzo[b]thiophene-2-yl; 2-pyrrolyl; 3-pyrrolyl; 1,3,5-triazin-2-yl; pyrazin-2-yl; pyridazin-3-yl; pyridazin-4-yl; 2-quinolinyl; 3-quinolinyl; 4-quinolinyl; 1-isoquinolinyl; 3-isoquinolinyl; and 4-isoquinolinyl; or substituted heterocycle, wherein the substituents (1-2 in number) are in any position and are independently selected from the group consisting of Br, Cl, F, R 1 , and C(O)CH 3 ; R 3 are the same or different and independently selected from the group consisting of: H; C 1 -C 4 -straight chain alkyl; C 3 -C 4 -branched chain alkyl; C 2 -C 4 -alkenyl chain; (CH 2 ) n Ph; and (CH 2 ) n -substituted phenyl, wherein the phenyl substituents are as defined above in R 2 ; R 4 =H; C 1 -C 4 -straight chain alkyl; or C 3 -C 4 -branched chain alkyl; R 3 and R 4 can be linked together by a carbon chain to form with intervening atoms a 5-8-membered saturated or unsaturated ring; n 1 =0-3; n=0-3; A=CH 2 ; (CH 2 ) 2 ; (CH 2 ) 3 ; OCH 2 CH 2 ; or CHCH 3 ; Y=H; OR 1 ; N(R 1 ) 2 ; N(R 1 )C(O)R 3 ; N(R 1 )C(O)R 5 ; N(R 1 )C(O)CH(R 6 )NH 2 ; N(R 1 )SO 2 R 3 ; N(R 1 )C(O)NHR 3 ; or N(R 1 )C(O)OR 6 ; R 5 =C 3 -C 7 -cycloalkyl; R 6 =C 1 -C 4 -straight chain alkyl; C 3 -C 4 -branched chain alkyl; C 2 -C 4 -alkenyl chain; (CH 2 ) n Ph; or (CH 2 ) n -substituted phenyl, wherein the phenyl substituents are as defined above in R 2 ; or a pharmaceutically acceptable salt thereof.