Patent ID: 7378079

Claim:
A diagnostic agent comprising a compound represented by the structure set forth in formula (II): and pharmaceutically acceptable salts, hydrates, solvates and metal chelates of the compound of the formula II; wherein G groups may be the same or different and are selected independently from hydrogen, —(CH2) m (COOH) and COOH such that said compound of formula II contains one or two carboxyl groups, wherein m is an integer of 1,2 or 3; V groups are independently absent or —(CH 2 ) k —; k being 1 or 2; M groups are independently absent or selected from the group consisting of hydrogen, alkyl-amide, hydroxyalkyl and fluoroalkyl, wherein said alkyl has 1, 2 or 3 carbon atoms; and T is —O—, —S—, —NH—, —N(B)—, —Q—, and —N(B′—Q)—, —N(B′—OH)—, -and —N(B′—F)— wherein B is an optionally substituted alkyl of 1, 2, 3, 4, 5 or 6 carbon atoms and B′ is an optionally substituted alkylene of 1 2, 3, 4, 5 or 6 carbon atoms; Q is a marker for imaging and a metal chelate; said marker for imaging being selected from the group consisting of a fluorescent label, a radio-label, a marker for X-ray, a marker for MRI, or a marker for PET scan; and R is independently selected from the group consisting of hydrogen, linear or branched alkyl of 1, 2, 3 or 4 carbon atoms, or the group (CH 2 ) m CH(NH 2 )COOH, wherein m is an integer of 0, 1, 2, 3 or 4; and a metal.