Patent ID: 7858598

Claim:
A compound of Formula (I): wherein X is halo; each of R 1 , R 2 , R 4 , and R 5 is independently hydrogen, halo, alkyl, halogenated alkyl, heteroalkyl, alkenyl, alkynyl, aryl, aralkyl, alkaryl, heterocyclyl, cycloalkyl, cycloalkenyl, cycloalkynyl, amino, alkylamino, arylamino, dialkylamino, alkylarylamino, diarylamino, hydroxy, thio, alkoxy, alkylthio, alkoxyalkyl, cyano, nitro, sulfonyl, phosphonyl, sulfonate ester, phosphate ester, —C(═O)—Y or —C(═O)-Q-Y; and each of R 3 and R 6 is independently hydrogen, halo, halogenated alkyl, heteroalkyl, alkenyl, alkynyl, aralkyl, alkaryl, heterocyclyl, cycloalkyl, cycloalkenyl, cycloalkynyl, amino, alkylamino, arylamino, dialkylamino, alkylarylamino, diarylamino, hydroxy, thio, alkoxy, alkylthio, alkoxyalkyl, cyano, nitro, sulfonyl, phosphonyl, sulfonate ester, phosphate ester, —C(═O)—Y or —C(═O)-Q-Y; wherein Y is hydrogen, halo, alkoxy, hydroxy, thio, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl, alkaryl, arylalkyl, carbamate, amino, alkylamino, arylamino, dialkylamino, alkylarylamino, diarylamino, alkylthio, heteroalkyl, or heterocyclyl having from 3 to 7 ring atoms; and Q is alkylene, alkenylene, alkynylene, arylene, aralkylene or alkarylene, or R 1 and R 2 or R 2 and R 3 or R 4 and R 5 or R 5 and R 6 together form a 5-, 6-, or 7-membered cycloalkyl, cycloalkenyl, aryl, heteroalkyl or heteroaryl ring; Z is a bond or a divalent linking group; R has one of Formulae (IIIA), (IVA) and (VA): wherein each of R 7 , R 8 and R 9 is independently hydrogen, halo, alkyl, halogenated alkyl, alkenyl, alkynyl, aryl, aralkyl, alkaryl, heterocyclyl, cycloalkyl, cycloalkenyl, cycloalkynyl, hydroxy, thio, alkoxy, alkylthio, alkoxyalkyl, cyano, nitro, carboxyl, acyl, carbamate, amido, amino, alkylamino, arylamino, dialkylamino, alkylarylamino, diarylamino, or heteroalkyl, or R 7 and R 8 of Formula (IIIA), (IVA) or (VA) or R 8 and R 9 of Formula (IVA) together form a 5-, 6-, or 7-membered cycloalkyl, cycloalkenyl, aryl, heteroalkyl or heteroaryl ring; and each of Q 1 and Q 2 is independently amino or —O-Q 3 , where Q 3 is hydrogen, alkyl, alkenyl, alkoxyalkyl, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl, alkaryl, arylalkyl, alkylamido, alkoxyamido, alkoxycarbonyl, halogenated alkyl or heteroalkyl, with the proviso that Q 1 and Q 2 are not both amino.