Patent ID: 7897374

Claim:
An intestine-binding Laclobacillus gasseri , having the ability to bind to a human A blood group antigen represented by [GalNAcαl-3(Fucαl-2)Gal-], wherein said lactobacillus is selected by the following criteria: (i) blood group A antigen-recognizing ability obtained by BIACORE1000 measurement using a blood group A antigen probe is 2,000 RU or higher; (ii) blood group B antigen-recognizing ability' obtained by BIACORE1000 measurement using a blood group B antigen probe is 100 RU or lower; (iii) blood group H antigen-recognizing ability obtained by BIACORE1000 measurement using a blood group H antigen probe is 100 RU or lower; (iv) the ratio of the A antigen-recognizing ability to the B antigen-recognizing ability is 70 or higher; (v) the ratio of the A antigen-recognizing ability to the H antigen-recognizing ability is 100 or higher; (vi) A-human colonic mucin (A-HCM)-recognizing ability obtained by BIACORE1000 measurement using HCM is 100 RU or higher; and (vii) O-HCM-recognizing ability obtained by BIACORE1000 measurement using HCM is 100 RU or lower, wherein the intestine-binding Lactobacillus gasseri is selected from the group consisting of Lactobacillus gasseri Accession No.: NITE BP-26 and Lactobacillus gasseri Accession No.: NITE BP-27.