Patent ID: 8722746

Claim:
A hydroxyphenyl derivative of formula (I) R1 is phenyl optionally substituted by 1 to 3 R identical or different, R being selected from the group comprising H, fluoro, C 1 -C 8 alkyl, C 1 -C 4 fluoroalkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, COOR a , COR a , CONR a R b , OCOR a , CN, OR a , NR a R b , CR a ═NOR b , NR a COOR b , OCONR a R b , NR a CONR b R c , SR a , SO 2 R a , SO 2 NR a R b and NR a C (S)NR b R c , all being possibly substituted by R′, R2 is C 1 -C 8 alkyl, C 2 -C 8 alkenyl , C 2 -C 8 alkynyl, C 1 - C 4 fluoro-alkyl, C 2 -C 4 fluoro-alkenyl, OR a , SR a , all being possibly substituted by 1 to 3 identical or different R′, R a , R b and R c , identical or different, are selected from the group consisting of H, C 1 -C 8 alkyl , C 2 -C 8 alkenyl , and C 2 -C 8 alkynyl, as defined above for R2, R′ is selected from the group comprising C 1 -C 8 alkyl, CH 2 CO 2 R″, CO 2 R″, COR″, CONR″R″′, OCOR″, OR″, NR″R″′, NR″COR″′, NR″COOR′″, OCONR″R′″, NR″CONR″R″′, NR″SO 2 R″′, SO 2 R″, NR″SO 2 R″′, halogen and CN, R″ and R″′, identical or different, are H or C 1 -C 8 alkyl Y represents H Z1 and Z3, identical or different, are halogen or H, and Z2 is fluoro; or a pharmaceutically acceptable organic or mineral salt thereof, in case the derivative of formula (I) has one or more chiral centres, both a chiral and non-chiral derivative, in cases the derivative of formula (I) has unsaturated carbon=carbon double bonds, both the cis (Z) and trans (E) isomers, and any N-oxide form of the derivatives, wherein the hydroxyphenyl derivative of formula (I) is not