Patent ID: 6958336

Claim:
A compound of formula I diastereomers, enantiomers or salts thereof where Q 2 is phenyl; Z is (1) —O—, (2) —S—, (3) —CR 4 R 5 —, (4) —CR 4 R 5 —O—CR 4a R 5a —, (5) —CR 4 R 5 —NR 4b —CR 4a R 5a —, or (6) —S—CR 4 R 5 —, R 1 , R 1ab , R 1ac and R 1ad are independently (1) hydrogen or R 6 , (2) —OH or —OR 6 , (3) —C(O) q H or —C(O) q R 6 , where q is 1 or 2, (4) halo, (5) -Z 4 -NR 7 R 8 , R 2 and R 3 are each independently H or -Z 4 -R 6a ; R 6 , R 6a , and R 6b are independently alkyl, cycloalkyl, aryl, or aralkyl, each of which is unsubstituted or substituted with Z 1 , Z 2 and one or more groups Z 3 ; R 4 , R 4a , R 4b , R 5 and R 5a are each independently hydrogen, alkyl, aryl, aralkyl, or cycloalkyl; R 7 and R 8 are each independently hydrogen or -Z 4 R 6b ; Z 3a is H, hydroxy, optionally substituted alkyl, —OZ 6 , —C(O)H, —C(O) q Z 6a , -Z 4 -NZ 7 Z 8 , or -Z 4 -N(Z 10 )-Z 5 -Z 6 ; Z 1 , Z 2 and Z 3 are each independently (1) hydrogen or Z, (2) —OH or —OZ 6 , (3) —C(O) q H or —C(O) q Z 6 , (4) halo, (5) -Z 4 -NZ 7 Z 8 , (6) -Z 4 -N(Z 10 )-Z 5 -Z 6 , (7) -Z 4 -N(Z 10 )-Z 5 -H, (8) oxo; Z 4 and Z 5 are independently (1) a single bond; (2) —C(O)—; (3) —S(O) q —; or (4) alkyl; Z 6 and Z 6a are independently (i) alkyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl, aryl, or aralkyl; (ii) a group (i) which is itself substituted by one or more of the same or different groups (i); or (iii) a group (i) or (ii) which is independently substituted by one or more of the groups (2) to (8) of the definition of Z 1 ; Z 7 , Z 8 and Z 10 are each independently hydrogen or -Z 4 -Z 6a ; provided that said compound is other than a compound of formula I where Q 2 is phenyl; Z is —S—; R 1 is hydrogen or R 6 ; R 1ab and R 1ac are independently hydrogen, R 6 or —OR 6 ; R 1ad is hydrogen; one of R 2 or R 3 is hydrogen or alkyl and the other R 2 or R 3 is -Z 4 -R 6a , where: Z 4 is —C(O)— and R 6a is phenyl substituted with Z 3 ; R 6 is alkyl; Z 3a is —C(O) q Z 6a , where q is 1; Z 1 and Z 2 are hydrogen; Z 3 is -Z 4 -NZ 7 Z 8 , where Z 4 is alkyl; Z 6a is alkyl; Z 7 and Z 8 are each independently hydrogen or -Z 4 -Z 6a , where Z 4 is a single bond.