Patent ID: 7592456

Claim:
A compound of the formula I: wherein: t is 2; each of X 1 , X 3 , and Y 1 represents CH or N and each of X 2 , Y 2 , and Y 3 represents CH, provided that X 1 and X 3 do not both represent N and provided that X 1 and Y 1 do not both represent N; Ar 1 represents phenyl, said phenyl bearing 0 to 3 substituents selected from halogen, CN, CF 3 , OCF 3 , C 1-6 alkyl, OH, C 1-6 alkoxy or hydroxyC 1-6 alkyl; Ar 2 represents phenyl, pyridyl or thienyl, said phenyl, pyridyl or thienyl bearing 0 to 3 substituents selected from halogen, CN, nitro, R a , OR a , SR a , SOR a , SO 2 R a , SO 2 NR a R b , (CH 2 ) x NR a R b , (CH 2 ) x NR a COR b , (CH 2 ) x NR a CO 2 R b , (CH 2 ) x NR a CONR a R b (CH 2 ) x NR a SOR b , (CH 2 ) x NR a SO 2 R b , (CH 2 ) x NR a SO 2 NR a R b , (CH 2 ) x COR a , (CH 2 ) x CO 2 R a , (CH 2 ) x CONR a R b , N═CHN(CH 3 ) 2 or (CH 2 ) x CR a ═NOR b , where x is 0 or 1, or said phenyl, pyridyl or thienyl may be substituted with (CH 2 ) x Ar 3 , COAr 3 or CH(OH)Ar 3 where Ar 3 represents a five- or six-membered heteroaromatic ring optionally bearing up to 2 substituents selected from halogen, CN, CF 3 , OH, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylthio, amino, C 1-6 alkylamino or di(C 1-6 )alkylamino; R a and R b independently represent H or a hydrocarbon group of up to 7 carbon atoms which is optionally substituted with up to 3 halogen atoms or with up to 2 substituents selected from CN, OH, C 1-4 alkoxy, C 1-4 alkylthio, amino, C 1-4 alkylamino and di(C 1-4 )alkylamino; or R a or R b , when linked through a nitrogen atom, together represent the residue of a heterocyclic ring of 4, 5 or 6 members, optionally bearing up to 3 substituents selected from halogen, CN, CF 3 , oxo, OH, C 1-4 alkyl or C 1-4 alkoxy; or two R a groups, when attached to adjacent carbon atoms of Ar 2 , may form a fused ring of 5 or 6 members, 0-3 of which are selected from N, O or S while the remainder are carbon, said ring optionally bearing up to 3 substituents selected from halogen CN, CF 3 , oxo, OH, C 1-4 alkyl or C 1-4 alkoxy; and wherein any nitrogen atom forming part of a heteroaromatic ring may be in the form of the N-oxide; or a pharmaceutically acceptable salt thereof.