Patent ID: 6942852

Claim:
A compound of the formula: R 1 -RANTES (2-68) where R 1 is CH 3 —(CH 2 ) n —X—; in which X is —C(O)—NH—CH 2 —C(O)—, —NHCH 2 —C(O)—, —ONH—CH 2 —C(O)—, —OCH 2 —CH 2 —C(O)—, —CH═CH—C(O)—, —C(O)—, or a covalent bond; and n is an integer of 4-8; and in which RANTES (2-68) is a polypeptide having the sequence: PYSSDT TPCCFAYIAR PLPRAHIKEY FYTSGKCSNP AVVFVTRKNR QVCANPEKKW VREYINSLEM S (SEQ ID No. 2) or is a polypeptide having a variant of said sequence, the variant sequence having at least 80% sequence homology with said sequence; wherein said compound inhibits HIV-1 R5 virus infection of PBMCs in vitro; or a pharmaceutically acceptable salt thereof.