Patent ID: 7858397

Claim:
A test device for detecting or quantifying an analyte in a test sample, the test device comprising a membrane, the membrane comprising: a contact portion at or proximate to a first end of the membrane; an immobilized liposome zone positioned adjacent the contact portion, wherein the membrane at the immobilized liposome zone has a sugar glaze on its outer surface and the immobilized liposome zone has bound thereto dehydrated, derivatized, marker-loaded liposomes dehydrated under vacuum pressure at a temperature of from about 4° C. to about 80° C.; an electrochemical measurement portion at a location on the membrane which is positioned away from the first end, wherein the electrochemical measurement portion comprises an electrochemical detector cell comprising a first conductor having a plurality of fingers, and a second conductor having a plurality of fingers, wherein the fingers of the first conductor are interdigitated with the fingers of the second conductor and are positioned on a glass substrate removably positioned adjacent and in contact with a surface of the membrane at the electrochemical measurement portion, and wherein the conductors induce redox cycling; and a liposome lysing portion segregated from the contact portion and immobilized liposome zone and having a liposome lysing agent bound thereto, wherein the liposome lysing portion either is positioned between the contact portion and the electrochemical measurement portion, or partially or completely coincides with the electrochemical measurement portion.