Patent ID: 8404689

Claim:
A compound of Formula I and enantiomers, diastereomers and pharmaceutically-acceptable salts thereof, wherein: R 1 is selected from the group consisting of substituted cycloalkyls, substituted heterocyclos selected from piperidine and piperazine, and substituted heteroaryls selected from pyrrole, furan, imidazole, isothiazole, triazole, dihydropyrrolopyrrolone, indole, pyrrolotriazine, and thiazolopyrimidinone; R 3 is selected from the group consisting of hydrogen, C 1 -C 4 alkyl and halogen; and R 4 is selected from the group consisting of hydrogen, optionally substituted carboxyls, optionally substituted alkyls, optionally substituted alkoxys, optionally substituted cycloalkyls, optionally substituted aryls, optionally substituted heterocyclos and optionally substituted heteroaryls; with the proviso that: R 4 is not optionally substituted pyrazolyl.