Patent ID: 7091213

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: A is —O—, —S— or —NR 2 — or is absent; Q is absent or (if A is —O—, —S— or —NR 2 —) Q may be —V—, —OV—, —SV—, or —NR 2 V—, where V is an unsubstituted aliphatic or heteroaliphatic, an aryl, or a 5–14 membered heteroaryl moiety having 1–4 heteroatoms selected from nitrogen, oxygen, or sulfur, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR 2 VA; K is O or S; each occurrence of Y is independently —O—, —S—, —NR 2 —, or a bond; each occurrence of R 2 and R 5 is independently H or an aliphatic, a heteroaliphatic, an aryl, or a 5–14 membered heteroaryl moiety having 1–4 heteroatoms selected from nitrogen, oxygen, or sulfur; and each occurrence of R 6 is independently —PK(YR 5 )(YR 5 ), —SO 2 (YR 5 ) or —C(O)(YR 5 ); so long as any R 2 or R 5 moiety linked directly to P is not H; wherein two R 2 , R 5 and/or R 6 moieties may be chemically linked to one another to form a ring; each occurrence of G is independently —O—, —S—, —NR 2 — or (M) x ; each occurrence of M is independently a substituted or unsubstituted methylene moiety, and any M—M moiety may be saturated or unsaturated; each occurrence of x is independently an integer from 1–6; wherein each aliphatic moiety contains 1–8 contiguous aliphatic carbon atoms, each heteroaliphatic moiety is an aliphatic moiety which contains an O, S, N, P or Si atom in place of one or more carbon atoms; each of the foregoing aliphatic and heteroaliphatic moieties is independently linear or branched, or cyclic or acyclic, and unsubstituted or substituted with one or more groups selected from halogen, —YR 2 , —Y—C(═O)R 2 , —NR 2 C(═O)R 5 , —NR 2 C(═O)NR 5 , —NR 2 C(═O)OR 5 , —NR 2 C(═NH)NR 5 , —Y—C(═O)OR 2 , —Y—C(═O)NR 2 R 5 , —Y—C(═NR 2 )NR 2 R 5 , —COCOR 2 , —COMCOR 2 ), J, —CN, —S(═O)R 2 , —SO 2 R 2 , —SO 2 NR 2 R 5 , —NO 2 , —NR 5 SO 2 R 2 —NR 5 SO 2 NR 2 R, ═O, ═S, ═NR 2 , ═NNR 2 R 5 , ═NNHC(O)R 2 , ═NNHCO 2 R 2 , and ═NNHSO 2 R 2 ; and each of the aryl, heteoraryl, acyl, aroyl or heteroaroyl moieties is independently unsubstituted or substituted with one or more groups selected from halogen, —YR 2 , —Y—C(═O)R 2 , —NR 2 C(═O)R 5 , —NR 2 C(═O)NR 5 , —NR 2 C(═O)OR 5 , —NR 2 C(═NH)NR 5 , —Y—C(═O)OR 2 , —Y—C(═O)NR 2 R 5 , —Y—C(═NR 2 )NR 2 R 5 , —COCOR 2 , —COMCOR 2 , J, —CN, —S(═O)R 2 , —SO 2 R 2 , —SO 2 NR 2 R 5 , —NO 2 , —NR 5 SO 2 R 2 and —NR 5 SO 2 NR 2 R; with the proviso that: J-Q-A- is not (HO) 2 (P═O)O— or (MeO) 2 (P═O)O—.