Patent ID: 8737709

Claim:
A computer-implemented method for correlating one or more features of biological tissue with a clinical outcome, the method comprising: rendering a graphical user interface on a visual display device; rendering, on the graphical user interface, a field of view selection component allowing a user to select a field of view from a data set of a cohort comprising tissue profile data including multiplexed biomarker images capturing expression of a plurality of biomarkers in a plurality of fields of view of biological tissue; in response to user input selecting a first biomarker and a first field of view corresponding to a biological tissue at the field of view selection component, rendering, on the graphical user interface, a first image of the selected first field of view corresponding to the biological tissue, the first image representing expression levels of the selected first biomarker and including representations of one or more biological units in the biological tissue; receiving, at the graphical user interface, a selection of a clinical outcome and a selection of a first set of one or more of the biological units in the biological tissue, wherein the selection of the first set of the biological units is made by a clustering algorithm implemented on a computing device that clusters the biological units based on expression levels of one or more biomarkers in the biological units; selectively displaying or highlighting the selected first set of biological units represented on the first image; and automatically determining and displaying a result of a correlation analysis performed between one or more features of the selected first set of biological units in the cohort and the selected clinical outcome.