Patent ID: 7855227

Claim:
A compound of formula I wherein: J is a group A-[(CH 2 ) n —O] r in para position with respect to the ethylamino chain wherein: n is zero or 1; and r is 1; A is trifluoromethyl; or phenyl optionally substituted with a halo group; W is (C 1 -C 4 )alkoxy; R is hydrogen; R 0 is hydrogen; or (C 1 -C 2 )alkyl; R 1 is hydrogen; (C 1 -C 4 )alkyl optionally substituted with a hydroxy group; cyclopropylmethyl; 2-propyn-1-yl; benzyl optionally substituted with one or two (C 1 -C 2 )alkoxy groups on the benzene ring; thiazolyl; a 5-6 membered saturated heterocyclyl containing a nitrogen atom, optionally substituted with a (C 1 -C 2 )alkyl group; or heterocyclylmethyl wherein the heterocyclyl group is a 5-6 membered heterocyclyl containing 1 to 3 hetero atoms selected from nitrogen, oxygen and sulfur, optionally substituted with one or two groups selected from (C 1 -C 2 )alkyl, hydroxymethyl and (C 1 -C 2 )alkoxy; R 2 is hydrogen; (C 1 -C 4 )alkyl; or phenyl; R 3 is hydrogen; or (C 1 -C 4 )alkyl; and R 4 is hydrogen; (C 1 -C 4 )alkyl optionally substituted with a group selected from amino, (C1-C4)alkylamino, di-(C 1 -C 4 )alkylamino, imidazolyl and pyrrolidinyl wherein the imidazolyl and the pyrrolidinyl group is optionally substituted with a (C 1 -C 2 )alkyl group; or benzyl; or R 3 and R 4 , taken together with the adjacent nitrogen atom, form a pyrrolidinyl, morpholinyl or piperazinyl ring optionally substituted with a (C 1 -C 2 )alkyl group; or a single optical isomer or mixtures thereof, or pharmaceutically acceptable salts of the single optical isomer or mixtures thereof.