Patent ID: 7989447

Claim:
A compound of the formula: or a pharmaceutically acceptable salt or prodrug thereof, wherein, R 1 is H, optionally substituted C 1-6 alkyl, optionally substituted C 1-4 alkaryl, optionally substituted C 1-4 alkheterocyclyl, or optionally substituted C 2-9 heterocyclyl; each of R 2 and R 3 is, independently, H, Hal, optionally substituted C 1-6 alkyl, optionally substituted C 6-10 aryl, optionally substituted C 1-6 alkaryl, optionally substituted C 2-9 heterocyclyl, or optionally substituted C 1-4 alkheterocyclyl; R 4 is H, R 4A C(NH)NH(CH 2 ) r4 , or R 4B NHC(S)NH(CH 2 ) r4 , wherein r4 is an integer from 0 to 2, R 4A is optionally substituted C 6-10 aryl, optionally substituted C 1-4 alkaryl, optionally substituted C 2-9 heterocyclyl, optionally substituted C 1-4 alkheterocyclyl, optionally substituted C 1-6 thioalkoxy, optionally substituted C 1-4 thioalkaryl, optionally substituted aryloyl, optionally substituted C 1-4 thioalkheterocyclyl, or substituted amino; R 4B is unsubstituted C 1-6 alkyl, optionally substituted C 6-10 aryl, optionally substituted C 2-9 heterocyclyl, optionally substituted C 1-6 thioalkoxy, optionally substituted C 1-4 thioalkaryl, optionally substituted aryloyl, optionally substituted C 1-4 thioalkheterocyclyl, or optionally substituted amino; and R 5 is H, R 5A C(NH)NH(CH 2 ) r5 , or R 5A NHC(S)NH(CH 2 ) r5 , wherein r5 is an integer from 0 to 2, R 5A is optionally substituted C 6-10 aryl, optionally substituted C 1-4 alkaryl, optionally substituted C 2-9 heterocyclyl, optionally substituted C 1-4 alkheterocyclyl, optionally substituted C 1-6 thioalkoxy, optionally substituted C 1-4 thioalkaryl, optionally substituted aryloyl, optionally substituted C 1-4 thioalkheterocyclyl, or optionally substituted amino; wherein one, but not both, of R 4 and R 5 is H, and when R 4 is H, R 1 is H, and when R 5 is H, R 3 is H.