Patent ID: 7317014

Claim:
A pyrimidine compound of the formula (I) and their pharmaceutically acceptable salts, wherein R 1 , R 2 , R 3 and R 4 may be same or different and independently represent hydrogen, hydroxy, nitro, nitroso, formyl, azido, halo or substituted or unsubstituted groups selected from alkyl, haloalkyl, alkoxy, aryl, aryloxy, aralkyl, aralkoxy, heteroaryl, heterocyclyl, acyl, acyloxy, cycloalkyl, amino, hydrazine, monoalkylamino, dialkylamino, acylamino, alkylsufonyl, arylsulfonyl, alkylsulfinyl, arylsulfinyl, alkylthio, arylthio, alkoxycarbonyl, aryloxycarbonyl, alkoxyalkyl, sulfamoyl, carboxylic acid and its derivatives; A represents pyrimidine of the structure wherein R 5 , R 6 , R 7 , may be same or different and represent, hydrogen, nitro, nitroso, formyl, azido, halo, or substituted or unsubstituted groups selected from alkyl, alkoxy, acyl, cycloalkyl, haloalkyl, amino, hydrazine, monoalkylamino, dialkylamino, acylamino, alkylsufonyl, alkylsulfinyl, arylsulfonyl, arylsulfinyl, alkylthio, arylthio, alkoxycarbonyl, aryloxycarbonyl, alkoxyalkyl, sulfamoyl, carboxylic acid and its derivatives; the pyrimidine group may be attached to the phenyl through carbon or nitrogen atom, wherein in structure (i) when at least one N is substituted, the substitution is not an alkyl, wherein in structure (iv) R 6 and R 7 are not hydrogen or an alkyl group, and wherein when one of R 6 and R 7 is a haloakyl group, the other is not a haloalkyl group and when one of R 6 and R 7 is an amino group the other is not an alkoxy, amino or amino substituted alkyl group.