Patent ID: 8679176

Claim:
A valve assembly for controlling fluid flow in a lumen having an annulus, the valve assembly comprising: a valve having a circumferential edge and defining a plurality of leaflets, wherein the valve and the defined plurality of leaflets are substantially planar in an unstressed position, wherein, in the unstressed position, the valve has a multi-lobal shape having a plurality of lobes defined on portions of the circumferential edge of the valve that extends outwardly from a central portion, wherein a portion of the valve adjacent the circumferential edge of the valve is configured for attachment to the annulus in a biased position, wherein each leaflet has a distal end portion that extends inwardly relative to the circumferential edge of the valve generally toward a radial center of the valve, wherein the valve has a modification ratio of between 1.01 to 1.5, wherein, upon attachment of the valve to the annulus in the biased position, the valve is substantially non-planar, the at least one leaflet is substantially non-planar, and the circumferential edge of the valve is positioned along the circumference of the annuli's in a substantially sinusoidal pattern, and wherein at least a portion of the valve comprises extracellular matrix material.