Patent ID: 6887898

Claim:
A method for the treatment of beta-Amyloid protein induced cytotoxicity in a human brain comprising administering to a subject suffering from the beta-Amyloid protein-induced cytotoxicity a therapeutically effective amount of a compound having the formula (I): or a compound having the formula (II): or a compound having the formula (III): or pharmaceutically acceptable salts or esters thereof, wherein: the dotted configuration- - - - is optionally a single bond or a double bond. R 1 is selected from the group consisting of H, OH, OMe, and OR 50 wherein R 50 is alkyl, alkenyl, or alkynyl; R 2 is selected from the group consisting of H, OMe, and OR 50 wherein R 50 is alkyl, alkenyl, or alkynyl; R 3 is selected from the group consisting of H, OMe, and OR 50 wherein R 50 is alkyl, alkenyl, or alkynyl; R 4 is selected from the group consisting of H, OH, OMe, and OR 50 wherein R 50 is alkyl, alkenyl, or alkynyl; R 5 is selected from the group consisting of H, OH, OMe, OR 50 , and X wherein R 50 is alkyl, alkenyl, or alkynyl, and X is F, Cl, Br, or I; R 6 is selected from the group consisting of OH, OMe, OR 50 , and X wherein R 50 is alkyl, alkenyl, or alkynyl, and X is F, Cl, Br, or I; R 7 is selected from the group consisting of H, OMe, and OR 50 wherein R 50 is alkyl, alkenyl, or alkynyl; R 8 is selected from the group consisting of OH, OMe, OR 50 and X wherein R 50 is alkyl, alkenyl, or alkynyl, and X is F, Cl, Br, or I; and R 9 is selected from the group consisting of H, OMe and OR 50 wherein R 50 is alkyl, alkenyl, or alkynyl.