Patent ID: 7977512

Claim:
A method of producing a benzonitrile derivative represented by the following general formula (1), using 4-dipropylaminobutyronitrile (3) as a raw material, the method comprising; subjecting the 4-dipropylaminobutyronitrile (3) to a reduction reaction to produce 4-dipropylaminobutylamine (4), and subjecting the primary amino group of the 4-dipropylaminobutylamine (4) to an alkylation reaction and a reductive alkylation reaction to produce the benzonitrile derivative represented by the general formula (1), wherein n represents an integer from 0 to 3; and R 1 represents hydrogen; a linear or branched alkyl group having 1 to 6 carbon atoms; a halogen atom; a nitro group; a cyano group; a carboxyl group; an amide group; a sulfonyl group; a hydroxyl group; a linear or branched alkoxy group having 1 to 6 carbon atoms; a linear or branched alkylcarbonyl group having 1 to 6 carbon atoms; a linear or branched alkoxycarbonyl group having 1 to 6 carbon atoms; a phenyl group; a phenyl group of which the aromatic ring is substituted by one or more of a halogen atom, a nitro group, a cyano group, a carboxyl group, an amide group, a sulfonyl group, a phenyl group, a linear or branched alkyl group having 1 to 6 carbon atoms, a linear or branched alkoxy group having 1 to 6 carbon atoms, a linear or branched alkylcarbonyl group having 1 to 6 carbon atoms, a linear or branched alkoxycarbonyl group having 1 to 6 carbon atoms, and a hydroxyl group; a benzoyl group; a benzoyl group of which the aromatic ring is substituted by one or more of a halogen atom, a nitro group, a cyano group, a carboxyl group, an amide group, a sulfonyl group, a phenyl group, a linear or branched alkyl group having 1 to 6 carbon atoms, a linear or branched alkoxy group having 1 to 6 carbon atoms, a linear or branched alkylcarbonyl group having 1 to 6 carbon atoms, a linear or branched alkoxycarbonyl group having 1 to 6 carbon atoms, and a hydroxyl group; a benzyloxycarbonyl group, a pyridyl group, a furyl group, an imidazolyl group, a triazolyl group, a tetrazolyl group, a naphthyl group, or a tetrahydrofuryl group, provided that, when n=0, R 1 represents hydrogen or a linear or branched alkyl group having 1 to 6 carbon atoms.