Patent ID: 7138405

Claim:
A method for treating the lower urinary tract symptoms associated with benign prostate hyperplasia in mammals comprising administering to a mammal suffering from benign prostate hyperplasia an effective amount of an alpha-adrenoceptor antagonist selected of the group of 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline, alfuzosin, indoramin, maftopidil, tamsulosin, doxazosin, tetrazosin, abanoquil, prazosin, phentolamine, trazodone, dapiprazole and phenoxybenzamine or pharmaceutically acceptable salts thereof in combination with a muscarinic antagonist selected from the group of darifenacin, atropine, fluvoxate, hyoscine, oxybutynin, tolterodine, propantheline, propiverine, and trospium, or pharmaceutically acceptable salts thereof.