Patent ID: 7943636

Claim:
A compound of the Formula I: wherein: Z is selected from the group consisting of: a bond, C 1-5 alkylene, X is selected from the group consisting of a bond, —C 2-3 alkylene-, and —O—C 2-3 alkylene-; R 1 is selected from the group consisting of: hydrogen, hydroxy, fluorine, alkoxy, —N(R 9 ) 2 , —NH-QR 4 , —S(O) 0-2 -alkyl, —S(O) 2 —NH—R 9 , —C(R 6 )—N(R 8 )—R 4 , —O—C(R 6 )—N(R 8 )—R 4 , —C(R 6 )—O-alkyl, —O—C(R 6 )—R 4 , and with the proviso that when Z is a bond, C 1-5 alkylene, and X is a bond, then R 1 is other than hydrogen; m is an integer from 1 to 5; R A and R B taken together form a fused benzo ring unsubstituted or substituted by one or more R groups; R is selected from the group consisting of: halogen, hydroxy, alkyl, haloalkyl, alkoxy, and —N(R 9 ) 2 ; R 2 is selected from the group consisting of: hydrogen, alkyl, alkoxyalkylenyl, hydroxyalkylenyl, haloalkylenyl, and R 4 —C(R 6 )—O—C 1-4 alkylenyl; R 4 is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, aryl, arylalkylenyl, aryloxyalkylenyl, alkylarylenyl, heteroaryl, heteroarylalkylenyl, heteroaryloxyalkylenyl, alkylheteroarylenyl, and heterocyclyl, wherein the alkyl, alkenyl, alkynyl, aryl, arylalkylenyl, aryloxyalkylenyl, alkylarylenyl, heteroaryl, heteroarylalkylenyl, heteroaryloxyalkylenyl, alkylheteroarylenyl, and heterocyclyl groups can be unsubstituted or substituted by one or more substituents independently selected from the group consisting of alkyl, alkoxy, hydroxyalkyl, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, mercapto, cyano, aryl, aryloxy, arylalkyleneoxy, heteroaryl, heteroaryloxy, heteroarylalkyleneoxy, heterocyclyl, amino, acetylamino, alkylamino, dialkylamino, (dialkylamino)alkyleneoxy, and in the case of alkyl, alkenyl, alkynyl, and heterocyclyl, oxo; R 6 is selected from the group consisting of ═O and ═S; R 8 is selected from the group consisting of hydrogen, alkyl, alkoxyalkylenyl, and arylalkylenyl; R 9 is selected from the group consisting of hydrogen and alkyl; R 11 is selected from the group consisting of hydrogen, alkyl, halogen, and trifluoromethyl; A is selected from the group consisting of —O—, —C(O)—, —S(O) 0-2 —, —CH 2 —, and —N(R 4 )—; Q is selected from the group consisting of a bond, —C(R 6 )—, —C(R 6 )—C(R 6 )—, —S(O) 2 —, —C(R 6 )—N(R 8 )—W—, —S(O) 2 —N(R 8 )—, —C(R 6 )—O—, and —C(R 6 )—N(OR 9 )—; V is selected from the group consisting of —C(R 6 )—, —O—C(R 6 )—, —N(R 8 )—C(R 6 )—, and —S(O) 2 —; W is selected from the group consisting of a bond, —C(O)—, and —S(O) 2 —; and a and b are independently integers from 1 to 6 with the proviso that a +b is ≦7; or a pharmaceutically acceptable salt thereof