Patent ID: 8796313

Claim:
A compound of Formula (I) wherein R 1 is H or C 1-6 alkyl, wherein the C 1-6 alkyl is optionally substituted with aryl, wherein said aryl is optionally substituted with C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, halo, nitro, hydroxyl, ethynyl, —CN, aryl, —SO 3 H, —C(O)OH, —C(O)NR′R″, —SR′, —OR′, —C(O)R′, —N(R′)(R″), —S(O) 2 —R′, and —S(O) 2 —N(R′)(R″), wherein R′ and R″ are independently selected from H, C 1-6 -alkyl, and aryl; R 2 is 0-3 members independently selected from halo, —OR 4 , —SR 4 , —S(O) 2 —R 4 , carboxy, nitro, hydroxyl, amido, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and amino optionally substituted with C 1-6 alkyl, aryl, wherein R 4 is selected from H, C 1-6 alkyl, and aryl; wherein said C 1-6 alkyl is optionally substituted with one to three groups selected from oxo, amino, alkoxy, carboxy, nitro, hydroxyl, and halo; wherein said C 2-6 alkenyl is optionally substituted with one to three groups selected from amino, alkoxy, carboxy, nitro, hydroxyl, and halo; wherein said C 2-6 alkynyl is optionally substituted with one to three groups selected from amino, alkoxy, carboxy, nitro, hydroxyl, and halo; wherein said aryl is optionally substituted with C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, halo, nitro, hydroxyl, ethynyl, —CN, aryl, —SO 3 H, —C(O)OH, —C(O)O—C 1-4 alkyl, —C(O)NR′R″, —SR′, —OR′, —C(O)R′, —N(R′)(R″), —S(O) 2 —R′, and —S(O) 2 —N(R′)(R″), wherein R′ and R″ are independently selected from H, C 1-6 -alkyl, and aryl; A is phenyl; B is pyridine, said pyridine being connected to N(1) through a ring carbon atom adjacent to a ring nitrogen, and said pyridine being further optionally substituted with 1 or 2 members selected from C 1-4 alkyl, C 2-4 alkenyl, halo, —CN, aryl, —SO 3 H, —C(O)OH, —C(O)O—C 1-4 alkyl, —OR 4 , —SR 4 , —C(O)R 4 , —N(R 4 )(R 5 ), —C(O)—N(R 4 )(R 5 ), —S(O) 2 —R 4 , and —S(O) 2 —N(R 4 )(R 5 ), wherein R 4 and R 5 are independently selected from H, C 1-6 alkyl, and aryl; wherein said C 1-6 alkyl is optionally substituted with one to three groups selected from oxo, amino, alkoxy, carboxy, nitro, hydroxyl, and halo; wherein said C 2-4 alkenyl is optionally substituted with one to three groups selected from amino, alkoxy, carboxy, nitro, hydroxyl, and halo; wherein said aryl is optionally substituted with C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, halo, nitro, hydroxyl, ethynyl, —CN, aryl, —SO 3 H, —C(O)OH, —C(O)O—C 1-4 alkyl, —C(O)NR′R″, —SR′, —OR′, —C(O)R′, —N(R′)(R″), —S(O) 2 —R′, and —S(O) 2 —N(R′)(R″), wherein R′ and R″ are independently selected from H, C 1-6 -alkyl, and aryl; X is C 1-3 alkylene, wherein said C 1-3 alkylene is optionally substituted with one or two groups selected from halo; and Y is —C(O)—, wherein said C(O) functionality is adjacent to N(1); or an optical isomer, enantiomer, diastereomer, racemate or pharmaceutically acceptable salt thereof.