Patent ID: 8877751

Claim:
A compound of formula I in which E, E′, E″, E′″ each, independently of one another, denote C or N, R 1 , R 2 each, independently of one another, denote H or A, or R 1 and R 2 together denote (CH 2 ) p , in which 1 or 2 CH 2 groups are optionally replaced by O and/or NH, R 3 denotes A, COA, (CH 2 ) n Het, Hal, O(CH 2 ) m NAA′ or O(CH 2 ) m Het, R 3′ denotes H or Hal, R 4 denotes Het 1 , NHCOOR 5 , NHCONHR 5 , NHCOCONHR 5 , NO 2 or NHCOA, R 4′ denotes H or Hal, or R 4 and R 4′ together denote NHCONH, R 5 denotes A, (CH 2 ) m NH 2 , (CH 2 ) m NHA, (CH 2 ) m NAA′ or (CH 2 ) m Het, Het denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, which is unsub-stituted or mono-, di- or trisubstituted by Hal, A, OR 6 , N(R 6 ) 2 , NO 2 , CN, COOR 6 , CON(R 6 ) 2 , NR 3 COA, NR 6 SO 2 A, SO 2 N(R 6 ) 2 , S(O) m A, NHCOOA, NHCON(R 6 ) 2 , CHO, COA, ═S, ═NH, ═NA and/or ═O, Het 1 denotes a monocyclic aromatic heterocycle having 1 to 4 N, O and/or S atoms, which is unsubstituted or mono-, di- or trisubstituted, in each case independently of one another, by R 3 , R 6 denotes H or A, A, A′ each, independently of one another, denote unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms are optionally replaced by F, Cl and/or Br, and/or in which one or two CH 2 groups are optionally replaced by O, S, SO, SO 2 and/or CH═CH groups, or cyclic alkyl having 3-7 C atoms, Hal denotes F, Cl, Br or I, m denotes 1, 2, 3 or 4, n denotes 0, 1, 2, 3 or 4, and p denotes 1, 2, 3, 4 or 5, or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof.