Patent ID: 8822444

Claim:
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: s is 0 or 1; L is -L 1 -L 2 -, wherein L 1 and L 2 are independently selected from: provided that at least one of L 1 and L 2 is other than Y and Y′ are independently oxygen (O) or NH; R 1 is hydrogen or —C(O)R x ; R 2 is hydrogen or —C(O)R y ; R x and R y are independently selected from cycloalkyl, heteroaryl, heterocyclyl, alkoxy, and alkyl substituted with one or more substituents independently selected from aryl, alkenyl, cycloalkyl, heterocyclyl, heteroaryl, —OR 3 , —C(O)OR 4 , —NR a R b , and —C(O)NR c R d , wherein aryl and heteroaryl may optionally be substituted with one or more substituents independently selected from alkyl, haloalkyl, arylalkyl, heterocyclyl, heterocyclylalkyl, halogen, cyano, nitro, —C(O)OR 4 , OR 5 , —NR a R b , (NR a R b )alkyl, and (MeO)(HO)P(O)O—, and wherein cycloalkyl and heterocyclyl may optionally be fused onto an aromatic ring and may optionally be substituted with one or more substituents independently selected from alkyl, hydroxyl, halogen, aryl, —NR a R b , oxo, and —C(O)OR 4 ; R 3 is hydrogen, alkyl, or arylalkyl; R 4 is alkyl or arylalkyl; R 5 is hydrogen, alkyl, or arylalkyl; R a and R b are independently selected from hydrogen, alkyl, cycloalkyl, arylalkyl, heteroaryl, —C(O)R 6 , —C(O)OR 7 , —C(O)NR c R d , and (NR c R d )alkyl, or alternatively, R a and R b , together with the nitrogen atom to which they are attached, form a five- or six-membered ring or bridged bicyclic ring structure, wherein said five- or six-membered ring or bridged bicyclic ring structure optionally may contain one or two additional heteroatoms independently selected from nitrogen, oxygen, and sulfur and may contain one, two, or three substituents independently selected from C 1 to C 6 alkyl, C 1 to C 4 haloalkyl, aryl, hydroxyl, C 1 to C 6 alkoxy, C 1 to C 4 haloalkoxy, and halogen; R 6 is alkyl; R 7 is alkyl, arylalkyl, cycloalkyl, or haloalkyl; R 100 and R 110 are independently selected from hydrogen, alkyl, cyanoalkyl, and halo; R c and R d are independently selected from hydrogen, alkyl, arylalkyl, and cycloalkyl.