Patent ID: 7576119

Claim:
A compound of formula (II): wherein: A is independently selected from hydrogen, a blocking group, L-H, L − , L-SM, a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aliphatic ether, a substituted or unsubstituted aromatic, a substituted or unsubstituted heteroaromatic; or a substituted or unsubstituted heterocyclic; SM is a support medium; L is —(C═O)—U—(C═O)—; U is cycloalkylene, arylene, heteroarylene, arylalkylene, alkarylene, or alkylenearylalkylene; G 1 is independently selected from O, S, (CR 1 R 2 ) h , NR 3 , O—(C═O), or (C═O)—O; h is 1, 2, or 3; each of R 1 and R 2 is independently selected from hydrogen, a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aromatic, a substituted or unsubstituted heteroaromatic, or a substituted or unsubstituted heterocyclic; R 3 is independently selected from hydrogen, a blocking group, a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aromatic, a substituted or unsubstituted heteroaromatic, or a substituted or unsubstituted heterocyclic; each of R U , R V , R W , R X , R Y , and R Z is independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, or substituted or unsubstituted alkynyl; each of Q and W is independently selected from hydrogen, a blocking group, L-H, L − , L-SM, a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aromatic, substituted or unsubstituted heteroaromatic, a substituted or unsubstituted heterocyclic, a protected or unprotected nucleosidyl moiety, a protected or unprotected nucleosidyl moiety attached through a phospholinker, or a protected or unprotected oligonucleotidyl moiety; and each of Y 1 and Y 2 is independently selected from O, S, NR 3 , or CR 1 R 2 ; wherein at least one of A, Q, or W is L-H, L − , or L-SM.