Patent ID: 8703977

Claim:
A compound of formula (I): wherein R 1 and R 1″ are each independently selected from the group consisting of: H, OH, alkoxy, C 1-10 alkylcarbonyl, phosphoryl, phosphonate, phosphinate, phosphonoamidate, halo, CN, NO 2 , N 3 , NH 2 , acylamino, amido, amidino, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, carbonyl, thiocarbonyl, acyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, sulfonyl, sulfoxido, sulfate, sulfonate, sulfamoyl, sulfonamide, C 1-6 alkyl-O—C 1-6 alkyl, C 1-6 alkyl-O-alkenyl, C 1-6 alkyl-O-alkynyl, C 1-6 alkyl-S—C 1-6 alkyl, C 1-6 alkyl-S-alkenyl, C 1-6 alkyl-S-alkynyl, CONH 2 , COOR, CH 2 CN, CH 2 N 3 , and with the proviso that one of R 1 and R 1″ , but not both, is wherein R is selected from the group consisting of: H; C 1-6 alkyl, C 2-6 alkenyl, or C 2-6 alkynyl, each of which is optionally substituted; CN, N 3 , halo, OH, CONH 2 , NH 2 , and amidino; wherein R 7 and R 7″ are each independently selected from the group consisting of: H, OH, alkoxy, C 1-10 alkylcarbonyl, phosphoryl, phosphonate, phosphinate, phosphonoamidate, halo, CN, NO 2 , N 3 , NH 2 , acylamino, amido, amidino, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, carbonyl, thiocarbonyl, acyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, sulfonyl, sulfoxido, sulfate, sulfonate, sulfamoyl, sulfonamide, C 1-6 alkyl-O—C 1-6 alkyl, C 1-6 alkyl-O-alkenyl, C 1-6 alkyl-O-alkynyl, C 1-6 alkyl-S—C 1-6 alkyl, C 1-6 alkyl-S-alkenyl, C 1-6 alkyl-S-alkynyl, CONH 2 , COOR, CH 2 CN, CH 2 N 3 , and with the proviso that one of R 7 and R 7″ , but not both, is alkoxy or wherein R 8 and R 8″ are each independently selected from the group consisting of: H, OH, alkoxy, C 1-10 alkylcarbonyl, phosphoryl, phosphonate, phosphinate, phosphonoamidate, halo, CN, NO 2 , N 3 , NH 2 , acylamino, amido, amidino, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, carbonyl, thiocarbonyl, acyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, sulfonyl, sulfoxido, sulfate, sulfonate, sulfamoyl, sulfonamide, C 1-6 alkyl-O—C 1-6 alkyl, C 1-6 alkyl-O-alkenyl, C 1-6 alkyl-O-alkynyl, C 1-6 alkyl-S—C 1-6 alkyl, C 1-6 alkyl-S-alkenyl, C 1-6 alkyl-S-alkynyl, CONH 2 , COOR, CH 2 CN, and CH 2 N 3 ; R 2 -R 5 and R 2″ -R 5″ are each independently selected from the group consisting of: H, OH, alkoxy, C 1-10 alkylcarbonyl, phosphoryl, phosphonate, phosphinate, phosphonoamidate, halo, CN, NO 2 , N 3 , NH 2 , acylamino, amido, amidino, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, carbonyl, thiocarbonyl, acyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, sulfonyl, sulfoxido, sulfate, sulfonate, sulfamoyl, sulfonamide, C 1-6 alkyl-O—C 1-6 alkyl, C 1-6 alkyl-O-alkenyl, C 1-6 alkyl-O-alkynyl, C 1-6 alkyl-S—C 1-6 alkyl, C 1-6 alkyl-S-alkenyl, C 1-6 alkyl-S-alkynyl, CONH 2 , COOR, CH 2 CN, and CH 2 N 3 ; and R 6 and R 6″ are independently selected from the group consisting of H and alkyl.