Patent ID: 7723393

Claim:
A compound of formula (I-A): including pharmaceutically acceptable salts thereof wherein R 1 is H or F; R 3 is —(Y) z —R 8 ; z is 0 or 1; Y is —CH═CH—; each of R 6 and R 7 are selected from H or alkyl; when z is 0, then R 8 is —O(CH 2 ) t CN, —CO 2 H, —(CH 2 ) t CO 2 H, —O(CH 2 ) t CO 2 H, —O(CH 2 ) t OH, —O(CH 2 ) t O(CH 2 ) t OH, or —O(CH 2 ) t C(O)NH 2 ; when z is 1, then R 8 is —CO 2 H or —CONH 2 ; each t independently is 1 to 8; and X is —(CH 2 ) n —, where n is 0, 1, or 2, or O.