Patent ID: 7420029

Claim:
A function-inhibitor of PEPT1 (oligopeptide transporter 1) consisting of a rotaxane compound in which a number of cyclodextrins are threaded by linear molecules, and both ends of the linear molecules are capped with bulky substituents, to which a dipeptide or tripeptide recognized by PEPT1 is bound, wherein the linear molecules are selected from the group consisting of polyethyleneglycol, polypropylene glycol, or copolymer of polyethyleneglycol and polypropylene glycol, polyamino acid, and polysaccharides, and the bulky substituents are selected from the group consisting of an oligopeptide comprising a unit or units of any one of N-benzyloxycarbonyl-L-phenylalanine, alanine, valine, leucine, isoleucine, methionine, proline, phenylalanine, tryptophan, aspartic acid, glutamic acid, glycine, serine, threonine, tyrosine, cysteine, lysine, arginine, histidine.