Patent ID: 7982018

Claim:
A conjugate comprising a modified urocortin-2 peptide derivative, wherein the urocortin-2 peptide derivative comprises the amino acid sequence of SEQ ID NO: 76 with one amino acid substitution, wherein the amino acid at position 20, 22,or 25 of SEQ ID NO: 76 is substituted to lysine, wherein the urocortin-2 peptide derivative is modified by the covalent attachment of a reactive group to the urocortin-2 peptide derivative through a linking group, wherein the covalent attachment is at the epsilon amino group of the lysine in the urocortin-2 peptide derivative, wherein the reactive group is maleimido propionic acid (MPA), wherein the linking group is [2-(2-amino)ethoxy)]lethoxy acetic acid (AEEA), and wherein the reactive group is covalently attached to an albumin.