Patent ID: 8802853

Claim:
A compound of the formula (II): wherein: Z is —C≡C—; X′ is —CH(R 3 )—; R 1 is selected from the group consisting of: —Ar and —Ar′—Y—R 4 ; Ar is phenyl which can be unsubstituted or can be substituted by one or more substituents independently selected from the group consisting of alkyl, alkoxy, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, hydroxyalkyl, mercapto, cyano, carboxy, formyl, amino, alkylamino, and dialkylamino; Ar′ is phenylene; R 2 is selected from the group consisting of hydrogen and alkyl, wherein the alkyl group can be unsubstituted or substituted by one or more substituents independently selected from the group consisting of alkyl and alkoxy; Y is selected from the group consisting of: —C(R 6 )—, —C(R 6 )—O—, —O—C(R 6 )—, and —O—C(O)—O—; R 3 is hydrogen or C 1-10 alkyl; R 4 is selected from the group consisting of hydrogen, alkyl, and alkenyl; R 6 is ═O; and n is 0; or a pharmaceutically acceptable salt thereof.