Patent ID: 8808703

Claim:
A compound of Formula (I), or pharmaceutically acceptable salt thereof: wherein: R 1 is H, —C(O)—C 7 -C 18 alkyl or —C(O)—C 1 -C 6 alkyl; R 2 is C 7 -C 18 alkyl; R 3 is C 7 -C 18 alkyl; L 1 is —CH 2 O—, —CH 2 NR 7 C(O)— or —CH 2 OC(O)NR 7 —; L 2 is —O—, —NR 7 C(O)— or —OC(O)NR 7 —; R 4 is -L 3 R 5 or -L 4 R 5 ; R 5 is —N(R 7 ) 2 , -OR 7 , —P(O)(OR 7 ) 2 , —C(O)OR 7 , —NR 7 C(O)L 3 R 8 , —NR 7 C(O)L 4 R 8 , —OL 3 R 6 , —C(O)NR 7 L 3 R 8 , —C(O)NR 7 L 4 R 8 , —S(O) 2 0R 7 , —OS(O) 2 OR 7 , C 1 -C 6 alkyl, a C 6 aryl, a C 10 aryl, a C 14 aryl, 5 to 14 ring membered heteroaryl containing 1 to 3 heteroatoms selected from O, S and N, C 3 -C 8 cycloalkyl or a 5 to 6 ring membered heterocycloalkyl containing 1 to 3 heteroatoms selected from O, S and N, wherein the aryl, heteroaryl, cycloalkyl and heterocycloalkyl of R 5 are each unsubstituted or the aryl, heteroaryl, cycloalkyl and heterocycloalkyl of R 5 are each substituted with 1 to 3 substituents independently selected from —OR 9 , —OL 3 R 6 , —OL 4 R 6 , —OR 7 , and —C(O)OR 7 ; L 3 is a C 1 -C 10 alkylene, substituted with 1 to 4 R 6 groups, or the C 1 -C 10 alkylene of L 3 is substituted with 2 C 1 -C 6 alkyl groups on the same carbon atom which together, along with the carbon atom they are attached to, form a C 3 -C 8 cycloakyl; L 4 is —((CR 7 R 7 ) p O) q (CR 10 R 10 ) p — or —(CR 11 R 11 )((CR 7 R 7 ) p O) q ((CR 10 R 10 ) p —, wherein each R 11 is a C 1 -C 6 alkyl groups which together, along with the carbon atom they are attached to, form a C 3 -C 8 cycloakyl; each R 6 is independently selected from halo, C 1 -C 6 alkyl, C 1 -C 6 alkyl substituted with 1-2 hydroxyl groups, —OR 7 , —N(R 7 ) 2 , —C(O)N(R 7 ) 2 , —P(O)(OR 7 ) 2 , a C 6 aryl, a C 10 aryl and a C 14 aryl; each R 7 is independently selected from H and C 1 -C 6 alkyl; R 8 is selected from —SR 7 , —C(O)OH, —P(O)(OR 7 ) 2 , and a 5 to 6 ring membered heterocycloalkyl containing 1 to 3 heteroatoms selected from O and N; R 9 is phenyl; each R 10 is independently selected from H and halo; each p is independently selected from 1, 2, 3, 4, 5 and 6, and q is 1, 2, 3 or 4.