Patent ID: 8536348

Claim:
A method of treating an infection or a disease or disorder caused by an infection in a patient, the method comprising administering to a human patient in need thereof a pharmaceutical composition comprising a compound of Formula Ia wherein R 1 -R 6 taken independently are selected from the group consisting of hydrogen, C 1 -C 8 alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, halogen, hydroxyl, alkoxy, substituted alkoxy, phenoxy, substituted phenoxy, aroxy, substituted aroxy, alkylthio, substituted alkylthio, phenylthio, substituted phenylthio, arylthio, substituted arylthio, cyano, isocyano, amino, substituted amino, sulfonyl, substituted sulfonyl, sulfonic acid, phosphoryl, substituted phosphoryl, phosphonyl, substituted phosphonyl, polyaryl, or substituted polyaryl; Z is a heteroatom selected from the group consisting of oxygen, sulfur, and nitrogen; and X is a heteroatom selected from the group consisting of oxygen, sulfur, and nitrogen; or a pharmaceutically acceptable salt thereof; and a pharmaceutical carrier for enteral, parenteral, or topical administration, wherein the pharmaceutical composition comprises an effective amount of the compound of Formula Ia to treat an infection or a disease or disorder caused by an infection.