Patent ID: 7109164

Claim:
A method for treating obesity, hypercolesterolemia atherosclerosis, depression, osteoporosis, hypothyroidism, goiter, glaucoma, cardiac arrhythmia, congestive heart failure, or a skin disorder or disease, which comprises administering to a patient in need of treatment a therapeutically effective amount of a compound of the formula wherein X is oxygen (—O—), sulfur (—S—), carbonyl (—CO—), methylene (—CH 2 —), or —NH—; Y is —(CH 2 ) n — where n is an integer from 1 to 5, or —C═C—, which is cis or trans; R 1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7 carbons; R 2 and R 3 are the same or different and are hydrogen, halogen, alkyl of 1 to 4 carbons or cycloalkyl of 3 to 6 carbons, at least one of R 2 and R 3 being other than hydrogen; R 4 is hydrogen or lower alkyl; R 5 is hydrogen or lower alkyl; R 6 is carboxylic acid, or ester thereof, or a prodrug thereof; R 7 is hydrogen, or an alkanoyl or aroyl group, or other group capable of bioconversion to generate the free phenol structure (wherein R 7 =H); including all stereoisomers thereof, a prodrug thereof, or a pharmaceutically acceptable salt thereof.