Patent ID: 8431611

Claim:
A compound having formula I: or an enantiomer, diastereomer, racemate or pharmaceutically acceptable salt or solvate thereof, wherein: is a double bond; n is independently an integer from 1 to 2; R 1 is independently substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroarylalkyl, —(CH 2 ) j R 2 , —(CH 2 ) j O(CH 2 ) k R 2 , —(CH 2 ) j C(O)(CH 2 ) k R 2 , —(CH 2 ) j OC(O)(CH 2 ) k R 2 , —(CH 2 ) j C(O) j O(CH 2 ) k R 2 , —(CH 2 ) k NR 3 R 4 , —(CH 2 ) j C(O)(CH 2 ) k NR 3 R 4 , —(CH 2 ) k NR 5 C(O)(CH 2 ) k R 2 , —(CH 2 ) J OC(O)(CH 2 ) k NR 3 R 4 , —(CH 2 ) J NR 5 C(O)(CH 2 ) k OR 2 , —(CH 2 ) j NR 5 C(O)(CH 2 ) k NR 3 R 4 , wherein each j and each k is independently an integer from 0 to 6; and m is independently an integer from 0 to 2; R 2 is independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, perfluoroalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted (aryl or heteroaryl)-X-(aryl or heteroaryl) wherein X is O, S, NH or N(C 1 -C 6 )alkyl, cholesterol, or a substituted or unsubstituted monosaccharide, and wherein each R 2 is optionally independently substituted with 1 to 5 R 10 groups; R 3 , R 4 , and R 5 are each independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, perfluoroalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, or substituted or unsubstituted heteroarylalkyl, wherein R 3 , R 4 , and R 5 , are each optionally independently substituted with 1 to 5 R 10 groups, or R 3 and R 4 , together with the N atom to which they are attached, form substituted or unsubstituted heterocycloalkyl, or substituted or unsubstituted heteroaryl, wherein substituted or unsubstituted heterocycloalkyl, and substituted or unsubstituted heteroaryl are each optionally independently substituted with 1 to 5 R 10 groups, and R 5 is as described above; and each R 10 is independently hydrogen, halogen, hydroxyl, amino, aminoalkyl, aminodialkyl, cyano, nitro, alkyl, —O-alkyl, —S-alkyl, perfluoroalkyl, —O— perfluoroalkyl, oxo, acetyl, or -benzyl, wherein: R 2 is not hydrogen, unsubstituted phenyl, or n-Bu when R 1 is —(CH 2 ) j C(O)(CH 2 ) k R 2 ; is a double bond; n is 2; and j and k are each independently 0; and R 1 is not unsubstituted thiazole or unsubstituted benthiazole when is a double bond; and n is 2.