Patent ID: 6908931

Claim:
A compound of Formula I wherein Ar is phenyl optionally substituted with 1-3 substituents selected from the group consisting of halogen, C 1-6 alkyl, and C 1-6 alkoxy, or Ar is 2,3-dihydrobenzfuran-4-yl; R 1 is C 1-6 alkyl or phenyl wherein phenyl is optionally substituted with 1-3 substituents selected from the group consisting of halogen, C 1-6 alkyl, and C 1-6 alkoxy; or Ar and R taken together with the carbon to which they are attached are 1-indanyl or 9-fluorenyl; R 2 , R 3 , R 4 , and R 5 are independently hydrogen, halo, C 1-3 alkoxy, or C 1-6 alkyl; or R 2 and R 3 taken together, R 3 and R 4 taken together, or R 4 and R 5 taken together are —O(CH 2 ) 2-3 — or —O(CH 2 ) 1-2 O—; R 6 is selected from the group consisting of hydrogen, C 1-9 alkyl, C 3-7 cycloalkyl, C 1-6 alkoxy, C 1-2 perfluoroalkyl, —CH 2 OC 1-3 alkyl, —(CH 2 ) 1-2 CO 2 R 7 , —(CH 2 ) 1-2 CO 2 NR 7 2 , —NR 7 2 , —CH 2 Cl, —CH 2 OCOMe, —CH 2 OPh, benzyl, 2-thienyl, 2-furanyl, 5-isoxazolyl, 4-biphenyl, naphthyl, 4-(1,2-methylenedioxy)phenyl, and phenyl where phenyl is optionally substituted with 1-3 substituents selected from halogen, C 1-3 alkoxy, C 1-2 perfluoroalkyl, C 1-2 perfluoroalkoxy, and nitro; and R 7 is hydrogen or C 1-6 alkyl; or a stereoisomer, pharmaceutically acceptable salt, or solvate thereof.