Patent ID: 8759318

Claim:
A compound of formula (I) below having the structure: wherein Ar is selected from naphthyl, any of which are optionally substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, di(C 1 -C 6 )alkylamino or C 1 -C 6 alkylcarboxy(C 1 -C 6 )alkyl-; X is selected from S, NH and O; R 1 is selected from C 1 -C 6 alkyl, benzyl, substituted benzyl; and aryl(C 0 -C 6 )alkyl- wherein the aryl is optionally substituted by halo, C 1 -C 6 alkoxy, and C 1 -C 6 alkyl; R 2 is selected from hydrogen, phenyl, aryl, and aryl(C 0 -C 6 )alkyl- wherein the aryl is optionally substituted by halo, C 1 -C 6 alkoxy, and C 1 -C 6 alkyl; R 3 is selected from H and OH; R 4 and R 5 are independently selected from hydrogen, C 1 -C 6 alkyl optionally substituted with alkylthio, benzyl optionally substituted with one or more halo, C 1 -C 6 alkyl, or C 1 -C 6 alkoxy, phenyl optionally substituted with one or more halo, C 1 -C 6 alkyl, or C 1 -C 6 alkoxy; R 6 is selected from C 1 -C 10 alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkyl-alkyl-, phenyl(C 1 -C 6 )alkyl- optionally substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, and halo, indanyl and heterocycloalkyl; and pharmaceutically acceptable salts thereof.