Patent ID: 8507199

Claim:
A compound having a structure according to Formula I: wherein each Z is a member independently selected from O and S; L 1 , L 2 , L 3 , L 4 , L 5 , L 6 , L 7 , L 8 , L 9 and L 10 are linker groups independently selected from substituted or unsubstituted C 1 to C 6 alkyl; A 1 , A 2 , A 3 and A 4 are members independently selected from the general structure: wherein each R 1 is a member independently selected from H, an enzymatically labile group, a hydrolytically labile group, a metabolically labile group and a single negative charge; and each R 5 , R 6 and R 7 is a member independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, halogen, CN, CF 3 , acyl, —SO 2 NR 17 R 18 , —NR 17 R 18 , —OR 17 , —S(O) 2 R 17 , —COOR 17 , —S(O) 2 OR 17 , —OC(O)R 17 , —C(O)NR 17 R 18 , —NR 17 C(O)R 18 , —NR 17 SO 2 R 18 , and NO 2 , wherein R 6 and a member selected from R 5 , R 7 and combinations thereof are optionally joined to form a ring system which is a member selected from substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; and R 17 and R 18 are members independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl and substituted or unsubstituted heterocycloalkyl, and R 17 and R 18 , together with the atoms to which they are attached, are optionally joined to form a 5- to 7-membered ring; and wherein at least one moiety selected from L 1 , L 2 , L 3 , L 4 , L 5 , L 6 , L 7 , L 8 , L 9 , and L 10 is substituted with: wherein L F is an acceptor-linker; F is a fluorophore bound to L F through a linkage fragment; and FM is a functional moiety, wherein said functional moiety comprises a reactive functional group, or said functional moiety is bound to a carrier moiety or solid support through a linkage fragment.