Patent ID: 7968718

Claim:
A process for preparing compound H having the structure which comprises a) treating compound G of the structure with a compound of the structure G a and potassium phosphate dibasic K 2 HPO 4 to form compound H; the reaction is carried out at a temperature within the range from about 60 to about 120° C. and in the presence of acetonitrile/dimethylacetamide; or b) treating compound G with methylsulfonyl hydrazide and 2,2-dimethoxyacetaldehyde f and K 3 PO 4 , to form compound H; the reaction is carried out at a temperature within the range from about 60 to about 100° C. and in the presence of acetonitrile/dimethylacetamide; and in compounds H and G, R 2 is F, R 18 is H and R 3 is H.