Patent ID: 7208481

Claim:
A method of modulating the production of apoE by an apoE producing cell, comprising contacting said apoE producing cell with an effective amount of a compound of formula (I): wherein A is an aryl group optionally substituted by one or more substituents independently selected from the group consisting of hydrogen, C 1 –C 8 alkyl, C 1 –C 8 alkoxy, halogen, nitro, amino, and NR 5 R 6 , where R 5 and R 6 are independently hydrogen or C 1 –C 4 alkyl; B is hydrogen, C 1 –C 8 alkyl group, or phenyl optionally substituted with one or more substituents independently selected from the group consisting of hydrogen, C 1 –C 8 alkyl, C 1 –C 8 alkoxy, hydroxy, halogen and cyano; m and n are independently selected are an integer from zero to 10, R 1 , R 2 , R 3 and R 4 are independently hydrogen or C 1 –C 6 alkyl, or a pharmaceutically acceptable salt thereof.