Patent ID: 7749693

Claim:
A method of determining effects of a substance on at least one organ, comprising: restoring and/or maintaining organ viability of the at least one organ, wherein the restoring and/or maintaining of the organ viability includes perfusing the organ with at least one medical fluid during at least one perfusion mode to restore and/or maintain pre-ischemia energy and enzyme levels of the organ; sensing tissue and/or fluid characteristics indicative of organ viability by a sensor to obtain diagnostic data; analyzing the diagnostic data to determine whether the at least one organ is suitable to be transplanted; and based on a determination that the at least one organ is not suitable to be transplanted, further comprising: perfusing the at least one organ with a first medical fluid to preserve the at least one organ; contacting the at least one organ with at least one test substance; and gathering data regarding at least one of the at least one organ, the at least one test substance, and interaction between the at least one organ and the at least one test substance.