Patent ID: 7226923

Claim:
A compound of formula I wherein R 1 , R 2 , R 3 and R 4 independently represent R 8 —X—, cycloalkyl-T 1 -, heterocyclyl-T 2 -, hydrogen, halogen, nitro, cyano, —OH, —NH 2 , —NH—C(O)H, —C(O)OH, —C(O)NH 2 , —S(O) 2 NH 2 , —NHC(O)NH 2 , —C(O)NH—O-alkyl, —C(O)N(alkyl)-O-alkyl, —NHC(O)NH—O-alkyl, —NHC(O)N(alkyl)-O-alkyl, —S(O) 2 NH—O-alkyl, —S(O) 2 N(alkyl)-O-alkyl, or alkyl optionally substituted one or several times by halogen, hydroxy or alkoxy; R 8 is cycloalkyl-T 1 -, heterocyclyl-T 2 -, aryl-T 3 -, heteroaryl-T 4 -, or alkyl optionally substituted one or several times by halogen; x is —C(O)NH—, —C(O)N(alkyl)-, —N(alkyl)C(O)—, —NHC(O)—, —NHC(O)NH—, —NHC(O)N(alkyl)-, —OC(O)N(alkyl)-, —NHS(O) 2 —, —S(O) 2 NH—, —S(O) 2 N(alkyl)-, —S(O) 2 —, —S(O)—, —C(O)O—, —OC(O)—, —C(O)—, —NH—, —N(alkyl)-, —O— or —S—; and T 1 , T 2 , T 3 and T 4 independently represent a single bond or alkylene optionally substituted one or two times by hydroxy; R 5 is hydrogen, alkyl being optionally substituted one or several times by halogen or alkoxy, heteroaryl, or phenyl, which is optionally substituted one or two times by halogen, —NO 2 , —OH, —C(O)OH, —C(O)NH-aryl, —C(O)NH 2 , —C(O)NH-alkyl, —C(O)N(alkyl) 2 , —C(O)-heterocyclyl, —NH 2 , —NHC(O)-aryl, —NHC(O)-cycloalkyl, —NHC(O)-alkyl, —N(alkyl)C(O)-alkyl, —NHC(O)O-alkyl, —N(alkyl)C(O)O-alkyl, —NHC(O)-alkoxyalkyl, —NH—S(O) 2 -aryl, —NH—S(O) 2 -alkyl, —C(O)NH—S(O) 2 -aryl, —C(O)NH—S(O) 2 -alkyl, —S(O) 2 -alkyl, —NH-aryl, —O-aryl, —S(O)-aryl, aryl, heterocyclyl, cycloalkyl, alkyl, alkoxy or alkylsulfanyl, said alkyl, alkoxy and alkylsulfanyl groups being optionally substituted one or several times by halogen; naphtyl, 1,3-Dihydro-isobenzofuranyl, benzo[1,3]dioxol-5-yl, cycloalkyl or alkenyl; Y is alkylene, alkylene-C(O)— or alkylene-CH(OH)—; n is 0 or 1; R 6 is hydrogen, alkyl, cyano or halogen; R 7 is hydrogen, alkyl or cycloalkyl; and a pharmaceutically acceptable salt thereof.