Patent ID: 7553489

Claim:
An antibody that immunospecifically binds to a respiratory syncytial virus (RSV) F antigen, wherein the antibody comprises: (a) a variable light (VL) chain having the amino acid sequence of SEQ ID NO:257; (b) a VL domain having the amino acid sequence of SEQ ID NO:76; (c) a variable heavy (VH) chain having the amino acid sequence of SEQ ID NO:256, and a VL chain having the amino acid sequence of SEQ ID NO:257; (d) a VH domain having the amino acid sequence of SEQ ID NO:48, and a VL domain having the amino acid sequence of SEQ ID NO:76; (e) a VH chain having the amino acid sequence of SEQ ID NO:256, and a VL domain having the amino acid sequence of SEQ ID NO:76; (f) a VH domain having the amino acid sequence of SEQ ID NO:48, and a VL chain having the amino acid sequence of SEQ ID NO:257; (g) a VH chain or VH domain comprising a VH complementary determining region (CDR) 1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid sequence of SEQ ID NO:20, and a VL chain or VL domain comprising a VL CDR1 having the amino acid sequence of SEQ ID NO:39, a VL CDR2 having the amino acid sequence of SEQ ID NO:77, and a VL CDR3 having the amino acid sequence of SEQ ID NO:6; (h) a VH chain having the amino acid sequence of SEQ ID NO:256, and a VL chain or VL domain comprising a VL CDR1 having the amino acid sequence of SEQ ID NO:39, a VL CDR2 having the amino acid sequence of SEQ ID NO:77, and a VL CDR3 having the amino acid sequence of SEQ ID NO:6; (i) a VH domain having the amino acid sequence of SEQ ID NO:48, and a VL chain or VL domain comprising a VL CDR1 having the amino acid sequence of SEQ ID NO:39, a VL CDR2 having the amino acid sequence of SEQ ID NO:77, and a VL CDR3 having the amino acid sequence of SEQ ID NO:6; (j) a VH chain or VH domain comprising a VH CDR1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid sequence of SEQ ID NO:20, and a VL domain having the amino acid sequence of SEQ ID NO:76; or (k) a VH chain or VH domain comprising a VH CDR1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid sequence of SEQ ID NO:20, and a VL chain having the amino acid sequence of SEQ ID NO:257.