Patent ID: 8574578

Claim:
A method of inhibiting growth of a primary tumor or a metastatic tumor in a patient in need thereof by administering to the patient an effective amount of an antibody or an antibody fragment thereof specific for human PDGFR alpha and comprising SSSYY (SEQ ID NO:2) at CDRH1; SFFYTGSTYYNPSLRS (SEQ ID NO:4) at CDRH2; QSTYYYGSGNYYGWFDR (SEQ ID NO:6) at CDRH3; RASQSVSSYLA (SEQ ID NO:10) at CDRL1; DASNRAT (SEQ ID NO:12) at CDRL2; and QQRSNWPPA (SEQ ID NO:14) at CDRL3, wherein the tumor is selected from the group consisting of a leiomyosarcoma and a glioblastoma.