Patent ID: 8324385

Claim:
A compound of formula (I): wherein X is nitrogen; R1 is -phenyl, unsubstituted or mono- or di-substituted independently with halogen, lower alkyl, lower alkanoic acid, lower alkanoyl, lower alkyl ester of lower alkanoic acid, haloloweralkyl, unsubstituted phenyl, halophenyl, alkoxyphenyl or phenyl substituted with haloloweralkyl, R2 is H, halogen or loweralkyl; and R3 is a piperazine ring, said ring being mono- or di-substituted, independently, with halogen, hydroxy, lower alkoxy, phenyl, phenyl substituted with haloloweralkyl, halophenyl, benzoic acid, lower alkyl ester of benzoic acid, lower alkyl oxadiazole, phenyl-pyridine, lower alkanoyl, lower alkanoic acid, lower alkyl ester of lower alkanoic acid, carbamic acid tert-butyl ester, N-alkyl carbamic acid tert-butyl ester, —CH 2 -halophenyl, —SO 2 -phenyl, acetylamino, methyltriazole, —C(O)NSO 2 —C(CH 3 ) 3 , benzoic acid benzyl ester, pyridine substituted with C(O)OH, phenyl substituted with lower alkanoic acid, phenyl substituted with lower alkyl ester of lower alkanoic acid, halobenzoic acid, lower alkyl benzoic acid, lower alkyl ester of halobenzoic acid, lower alkyl ester of lower alkyl benzoic acid, lower alkoxy benzoic acid, lower alkyl ester of lower alkoxy benzoic acid, lower alkoxy phenyl, 2,2-dimethyl-4-oxobutyric acid, 2-oxo-ethyl cyclopentanecarboxylic acid, 3,3-dimethyl-5-oxo-pentanoic acid, carbonyl-cyclohexanecarboxylic acid methyl ester, carbonyl-cyclopropane, (2,4-dioxo-thiazolidin-5-yl)-acetyl, carbonyl-ethyl-(3-hydroxy-isoxazol-5-yl), carbonyl-cyclohexanecarboxylic acid, carbonyl-cyclopentanecarboxylic acid, ethanesulfonylaminocarbonyl-cyclohexanecarbonyl, carbonyl-amino-propionic acid ethyl ester, carboxylic acid tert-butylamide, carboxylic acid ethylamide, carbonyl-amino-acetic acid ethyl ester, or —C(O)CH 2 C(CH 3 ) 3 ; or a pharmaceutically acceptable salt thereof.