Patent ID: 8301257

Claim:
A method for identifying and reducing a subject's risk of epilepsy, the method comprising: a) acquiring neural activity data from the subject; b) analyzing the acquired neural activity data by: b) i) calculating, from the acquired neural activity data, a parameter indicative of neuronal hyperexcitability due to imbalances between excitatory and inhibitory influences; b) ii) calculating, from the acquired neural activity data, a parameter indicative of spatial overconnectivity that leads to abnormally wide spreads of neuronal activity; and b) iii) calculating, from the acquired neural activity data, a parameter indicative of temporal overconnectivity that leads to abnormally persistent neuronal activity, wherein the parameter indicative of temporal overconnectivity accounts for non-Markovian effects; c) determining epileptic patterns in the subject based on the parameters calculated in step b); and d) administering a treatment to the subject configured to reverse the epileptic patterns determined in step c).