Patent ID: 6916797

Claim:
An α-arylethylpiperazine of formula I′ wherein Z represents an oxygen atom; n′ represents 1; R 2 represents a hydrogen atom or a methyl group; W represents (i) a cyclohexyl group substituted by a COOH, or (ii) a group of formula R 1 —(CH 2 ) n —X—(CH 2 ) m — in which R 1 represents a CN, CONHSO 2 alkyl, COOH, COOalkyl, SO 3 H, PO(OH) 2 , a phenyl group mono-substituted by COOH, a tetrazole of the formula or a triazolone of formula X represents a single bond, an oxygen atom or a methylene group; m represents 1 or 2, provided that m is not 1 when X is an oxygen atom; n represents 0, 1 or 2, Ar 1 represents phenyl, a mono-, di- or tri-substituted phenyl group in which the substituents are a halogen atom, an alkyl group, CN or NO 2; Ar 2 represents a substituted aryl group of formula in which R 3 represents a halogen atom or a trifluoromethyl group; p represents 1, 2 or 3; the alkyl groups being linear or branched and having 1 to 4 atoms of carbon, or non-toxic pharmaceutically acceptable salt, individual optical isomer, or individual diastereoisomer thereof.