Patent ID: 8377683

Claim:
A dynamic and noninvasive cell adhesion and cell proliferation monitoring system, comprising: a CO 2 incubator; a temperature control device disposed inside the incubator; one or more cell-growth wells deployed inside the incubator; a bulk acoustic wave (BAW) sensor device deployed inside at least one cell-growth well wherein the sensor device comprises: a piezoelectric layer; a conductive film serving as a bottom electrode deposited and patterned beneath said piezoelectric layer; a metal electrode serving as a top electrode deposited and patterned on said piezoelectric layer; and ZnO-based nanostructures deposited and patterned on a top surface of said top electrode; wherein wettability (from super hydrophobicity to super hydrophilicity, or vice versa) of said ZnO-based nanostructures can be controlled; and a real-time signal analyzing device connected to said sensor device.