Patent ID: 7018654

Claim:
A pharmaceutical composition comprising: (i) an active agent non-covalently linked in an internalized domain or pocket of an amino acid copolymer structure wherein said amino acid copolymer structure comprises at least one hydrophilic component and at least one hydrophobic component designed to promote the formation of said internalized domain or pocket; and (ii) said hydrophilic component and hydrophobic component are selected to manipulate the tertiary structure of said amino acid copolymer structure to control degradation and release of said active agent; wherein said hydrophilic component is lysine, arginine, asparagine, cysteine, glutamic acid or combinations thereof; wherein said hydrophobic component is valine, tyrosine, proline, leucine, tryptophan, methionine, phenylalanine, glycine, isoleucine, benzyl glutamic acid, or combinations thereof; and wherein said composition is in a form suitable for oral administration.