Patent ID: 8575168

Claim:
A compound selected from Formula I: or the pharmaceutically acceptable salts thereof; in which: n is selected from 0, 1, and 2; R 1 is selected from —S(O) 2 X 2 R 4a —C(O)OX 2 R 4a and —C(O)X 2 R 4a , X 2 OR 4a ; wherein X 2 is selected from a bond and C 1-4 alkylene; R 4a is selected from hydrogen, C 1-6 alkyl, halo-substituted-C 1-6 alkyl, hydroxy-substituted-C 1-6 alkyl, phenyl, and, C 3-8 heterocycloalkyl; wherein said heterocycloalkyl of R 4a is optionally substituted with C 1-6 alkyl or —C(O)OX 4 R 5c ; wherein X 4 is C 1-4 alkylene; R 5c is C 1-6 alkyl; R 2 is halo R 20 is selected from hydrogen and methyl; W 2 is selected from CR 7 and N; wherein R 7 is selected from hydrogen and halo; Y 1 is selected from CH 2 and C(O); or Y 1 and W 2 taken together can form a double bond where W 2 is C and Y 1 is CH; Y 2 , Y 6 and Y 7 are independently selected from N and CH, where at least one of Y 2 , Y 6 and Y 7 is CH; Y 5 is —CH 2 -; R 3 is selected from C 6-10 aryl and 5-6 membered heteroaryl; wherein said aryl or heteroaryl of R 3 is optionally substituted with 1 to 4 R 14 radicals; wherein each R 14 is independently selected from C 1-6 alkyl, halo, C 1-6 alkoxy, halo-substituted-C 1-6 alkyl, halo-substituted-C 1-6 alkoxy, and C 1-10 heterocycloalkyl; wherein the heterocycloalkyl of R 14 is optionally substituted by halo.