Patent ID: 8530406

Claim:
A peptide derived from human HMG-CoA reductase, of general formula (I) R 1 -(AA) n -X 1 -Gly-Glu-Leu-Ser-X 2 -X 3 -(AA) p -R 2 in which, X 1 is alanine, valine or isoleucine, X 2 is leucine, isoleucine or absent, X 3 is methionine, serine, alanine or absent, AA represents any amino acid, and n and p are integers between 0 and 4, with the proviso that when X 2 and X 3 are no amino acid, p is 0, R 1 represents the primary amine function of the N-terminal amino acid, free or substituted by a protecting group selected from an acetyl group, a benzoyl group, a tosyl group or a benzyloxycarbonyl group, R 2 represents the hydroxyl group of the carboxyl function of the C-terminal amino acid, free or substituted by a protecting group selected from an alkyl chain from C 1 to C 20 , or an NH 2 , NHY or NYY group with Y representing an alkyl chain from C 1 to C 4 .