Patent ID: 7279601

Claim:
A manufacturing method for an optically active α-aminooxy ketone derivative expressed by formula (1), wherein a ketone expressed by formula (2) is caused to react with a nitroso compound expressed by formula (3) in the presence of proline or a proline derivative expressed by formula (4): wherein in formulae (1)-(4), R 1 and R 2 respectively denote an alkyl, alkenyl or alkynyl group which may have a substituent, and R 1 and R 2 may be linked to form a ring; R 3 denotes an aryl, heterocyclic, alkyl, alkenyl or alkynyl group which may have a substituent; and A denotes a hydrocien atom, alkoxy group, aryloxy group, acyloxy group or silyloxy group which may have a substituent, and wherein A in formula (4) is a silyloxy group which may have a substituent.