Patent ID: 7803371

Claim:
A monoclonal antibody comprising: a) an antibody variable domain comprising: i. a heavy chain variable domain comprising: a CDR1 region identical to amino acid residues 30-35 of SEQ ID NO: 4, a CDR2 region identical to amino acid residues 50-66 of SEQ ID NO: 4 and a CDR3 region identical to amino acid residues 98-109 of SEQ ID NO: 4; and ii. a light chain variable domain comprising: a CDR1 region identical to amino acid residues 23-35 of SEQ ID NO: 43, a CDR2 region identical to amino acid residues 51-57 of SEQ ID NO: 43 and a CDR3 region identical to amino acid residues 90-101 of SEQ ID NO: 43; or b) a variant of said antibody variable domain that is otherwise identical to said antibody variable domain except for up to 8 amino acid substitutions in said CDR regions; wherein the antibody binds human VEGF.