Patent ID: 7732412

Claim:
A method of treating a hormone-influenced non-malignant disorder that is treatable by luteinizing hormone-releasing hormone (LH-RH) suppression, the method comprising administering to a patient in need of the treatment a therapeutically effective amount of a compound of the general formula I A-Xxx 1 -Xxx 2 -Xxx 3 -Xxx 4 -Xxx 5 -Xxx 6 -Xxx 7 -Xxx 8 -Xxx 9 -Xxx 10 -NH 2 (I) in which: A is an acetyl or a 3-(4-fluorophenyl)propionyl group, Xxx 1 is D-Nal(1) or D-Nal(2), Xxx 2 -Xxx 3 is D-Cpa-D-Pal,(3) or a single bond, Xxx 4 is Ser, Xxx 5 is N-Me-Tyr, Xxx 6 is D-Cit, D-Hci or a D-amino acid group of the general formula II in which n is the number 3 or 4, where R 1 is a group having the general formula III —(CH 2 ) p —CO—NR 2 R 3 (III) where p is an integer from 1 to 4, R 2 is hydrogen or an alkyl group and R 3 is an unsubstituted or substituted aryl group or heteroaryl group, or R 1 is a 3-amino-1,2,4-triazole-5-carbonyl group or R 1 is a ring of the general formula IV in which q is the number 1 or 2, R 4 is a hydrogen atom or an alkyl group, R 5 is a hydrogen atom or an alkyl group and X is an oxygen or sulphur atom, Xxx 7 is Leu or Nle, Xxx 8 is Arg or Lys(iPr), Xxx 9 is Pro, and Xxx 10 is Ala, D-Ala, or Sar, and their salts with pharmaceutically acceptable acids.