Patent ID: 7241784

Claim:
A compound of the formula (I) Wherein, A 1 is C1–4 alkylene, A 2 is C2–8 alkylene, C3–8 alkenylene or C3–8 alkynylene, E 1 is —O— or —S—, E 2 is —CH 2 —, —O— or —S(O) m —, m is 0, 1 or 2, each R 1 in (R 1 ) n independently, is hydrogen, C1–8 alkyl, halogen, C1–4 alkoxy, C1–4 alkylthio, nitro, NR 7 R 8 (in which R 7 and R 8 each independently, is C1–4 alkyl), cyano, trifluoromethyl, trifluoromethyloxy, carbocyclic ring or heterocyclic ring (in which carbocyclic ring and heterocyclic ring may be substituted with the group selected from C1–4 alkyl, C1–4 alkoxy, halogen or trifluoromethyl), R 2 is hydrogen, C1–8 alkyl, halogen, C1–4 alkoxy, C1–4 alkylthio, nitro, NR 7 R 8 (in which R 7 and R 8 each independently, is C1–4 alkyl), cyano, trifluoromethyl or trifluoromethyloxy, R 3 and R 4 each independently, is hydrogen or C1–4 alkyl or R 3 and R 4 taken together with carbon atom to which is attached represents C3–7 cycloalkylene, R 5 is —COOR 9 (in which R 9 is hydrogen or C1–4 alkyl), and n is 1–3, a non-toxic salt thereof, or hydrate thereof.