Patent ID: 7939547

Claim:
A compound of Formula (1): and pharmaceutically acceptable salts, and stereoisomers thereof, wherein J is Z is O or S; R 1 is —(CR 2 ) l —NR 2 , —(CR 2 ) l —NRC(═NR)—NR 2 , or —(CR 2 ) l —C(═NR)—NR 2 ; W—R 2 is a substituent at any position on ring A; W is or —O(CR 2 ) k —, —S(CR 2 ) k —, —S(O)(CR 2 ) k —, —SO 2 (CR 2 ) k — or —OC(O)(CR 2 ) k —; R 2 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, R 6 , —CR 9 ═CR 9 —R 6 , or wherein ring E is an optionally substituted 5-7 membered monocyclic or fused carbocyclic or heterocyclic ring; or W—R 2 together form C 1-6 alkyl, a 5-7 membered aryl or —OC(O)NR 7 R 8 ; R 3 is NR 7 R 8 or R 6 ; R 4 and R 5 are independently H, C 1-6 alkyl, OH, or C 1-6 alkoxy; R 7 and R 8 are independently H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl or —(CR 2 ) l —R 6 ; or R 7 and R 8 together with N may form an optionally substituted 5-7 membered monocyclic or fused heterocyclic ring; R 9 is H or C 1-6 alkyl; R 10 is halo, C 1-6 alkyl, C 1-6 alkoxy, OR 11 or —(CR 2 ) l —R 11 ; R 6 , R 11 and X are independently an optionally substituted 5-7 membered carbocyclic ring, heterocyclic ring, aryl or heteroaryl; or R 11 is H or C 1-6 alkyl; R is H; i is 0-1; k and l are independently 0-6; m and n are independently 1-6; and p is 0-3.