Patent ID: 8906923

Claim:
A compound of formula (I) wherein A represents —C≡C— or the bond represents a single bond or a double bond, X represents carbon or nitrogen, and when X represents nitrogen then the bond represents a single bond; Z 1 represents CH or N; R 1 is hydrogen, C 1-4 alkyl or halo; R 2 is hydrogen, C 1-4 alkyl or halo; R 3 is hydrogen, C 1-6 alkyl, hydroxy or halo; R 4 is hydrogen; halo; C 1-6 alkyl; C 2-6 alkenyl; C 2-6 alkynyl; C 1-6 alkyloxy; C 1-4 alkyloxycarbonyl; aminocarbonyl; mono- or di(C 1-4 alkyl)-aminocarbonyl; aryl; aryloxy; arylcarbonyl; arylsulfonyl; heteroaryl; C 1-6 alkyl substituted with cyano; C 1-6 alkyl substituted with aryl or aryloxy; or C 1-6 alkyl substituted with heteroaryl; aryl is phenyl; phenyl substituted with one, two or three substituents each individually selected from halo, hydroxy, C 1-4 alkyl, C 1-4 alkyloxy, polyhaloC 1-4 alkyl, polyhaloC 1-4 alkyloxy, cyano, nitro, and amino; heteroaryl is furanyl, thiophenyl, pyrrolyl, pyrazolyl, imidazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, benzo[1,3]dioxolyl, benzofuranyl, benzothiazolyl, indolyl, 2,3-dihydro-1H-indolyl, tetrahydrothiophenyl, or quinolinyl, wherein each heteroaryl may be substituted with one or two substituents each independently selected from halo, cyano, C 1-4 alkyl, C 1-4 alkyloxy, C 1-4 alkylcarbonyl, or phenyl; or a pharmaceutically acceptable acid addition salt thereof.