Patent ID: 7049443

Claim:
An oxazolidinone derivative of formula (I) wherein J is O or S; R 210 is R 310 , R 410 and R 510 each independently are a) H, b) C 1-4 alkyl, c) halogen, d) C 1-4 alkoxy, e) hydroxy, f) (CH 2 ) c OP(O)(OH) 2 , g) C 1-4 acyloxy, or h) C 1-4 alkyl substituted by halogen, hydroxy, acyloxy, NR 1210 R 1310 , or alkoxy; R 610 , R 710 and R 810 each independently are a) H, b) CH 3 , or c) C 2 H 5 ; R 910 and R 1010 each independently are a) H, b) CH 3 , c) C 2 H 5 , or d) combine to form a C 3-5 cycloalkyl; R 1110 is H or C 1-6 alkyl; R 1210 and R 1310 each independently are a) H, b) C 1-4 alkyl, or c) combine to form a heterocyclic ring; wherein a is 0 or 1, b is 0 or 1, and c is 0 or 1, with the proviso that when Q′ is b is 0; R 1 is a) C 1-4 alkyl, b) C 2-4 alkenyl, c) OC 1-4 alkyl, d) C 3-6 cycloalkyl, e) C 1-4 alkyl substituted with one to three F, one to two Cl, CN, —COOC 1-4 alkyl or a C 3-6 cycloalkyl, or f) H; G is A is R 23 and R 24 are each independently a) H, b) F, c) Cl, d) C 1-2 alkyl, e) CN f) OH, g) C 1-2 alkoxy, h) nitro, or i) amino; Q is wherein “ . . . ” is a bond or absent; E is a) NR 39 , b) —S(═O) i , or a) O; R 38 is a) H, c) —(CH 2 ) q -aryl, or d) F; R 39 is a) H, b) C 1-6 alkyl optionally substituted with one or more OH, halo, or —CN, c) —(CH 2 ) q -aryl, d) —CO 2 R 40 , e) —COR 41 , f) —C(═O)—(CH 2 ) q —C(═O)R 40 , g) —S(═O) 2 —C 1-6 alkyl, or h) —S(═O) 2 —(CH 2 ) q -aryl; R 40 is a) H, b) C 1-6 alkyl optionally substituted with one or more OH, halo, or —CN, c) —(CH 2 ) q -aryl, or d) —(CH 2 ) q —OR 42 ; R 41 is a) C 1-6 alkyl optionally substituted with one or more OH, halo, or —CN, b) —(CH 2 ) q -aryl, or c) —(CH 2 ) q —OR 42 ; R 42 is a) H, b) C 1-6 alkyl, c) —(CH 2 ) q -aryl, or d) —C(═O)—C 1-6 alkyl; aryl is a) phenyl, or b) pyridyl; i is 0, 1, or 2; n is 0, 1, 2, 3, 4, or 5; p is 0, 1, 2, 3, 4, or 5; with the proviso that n and p together are 1, 2, 3, 4, or 5; and q is 1, 2, 3, or 4.