Patent ID: 6949517

Claim:
A method of treating inflammatory conditions comprising administering to a mammal in need thereof an effective amount of a monosaccharide, in which said monosaccharide is substituted by at least three vicinal phosphorus containing radicals of the formula: wherein V 1 to V 4 are independently Y 8 m6 T o3 U; T 01 to T 03 are independently (CH 2 ) n , CH═CH, or CH 2 CH═CHCH 2 ; o1 to o3 are independently 0 or 1; n is 0 to 4; U is R 1 Y 9 m 7 , CY 10 Y 11 R 2 ,SY 12 Y 13 Y 14 R 3 ,PY 15 Y 16 Y 17 R 4 R 5 , Y 18 PY 19 Y 20 Y 21 R 6 R 7 , CH 2 NO 2 ,NHSO 2 R 8 , or NHCY 22 Y 23 R 9 ; m1 to m7 are independently 0 to 1; Y 1 to Y 23 are independently NR 10 ,NOR 11 ,O, or S; and where R 1 to R 11 are independently i) hydrogen; ii) a straight or branched saturated or unsaturated alkyl group containing 1-22 carbon atoms; iii) a saturated, unsaturated aromatic or non-aromatic homo- or heterocyclic group containing 3-22 carbon atoms and 0-5 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur; iv) a straight or branched saturated or unsaturated alkyl group containing 1-22 carbon atoms substituted with a saturated or unsaturated aromatic or non-aromatic homo- or heterocyclic group containing 3-22 carbon and 0-5 heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur; v) an aromatic or non-aromatic homo-or heterocyclic group containing 3-22 carbon and 0-5 heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur which aromatic or non-aromatic homo-or heterocyclic group is substituted with a straight or branched saturated or unsaturated group containing 1-22 carbon atoms; whereby said groups in ii-v are unsubstituted or are substituted by 1-6 of the following groups: hydroxy, alkoxy, aryloxy, acyloxy, carboxy, alkoxycarbonyl, alkoxycarbonyloxy, aryloxycarbonyl, aryloxycarbonyloxy, carbamoyl, fluoro, chloro, bromo, azido, cyano, oxo, oxa, amino, imino, alkylamino, arylamino, acylamino, arylazo, nitro, alkylthio or alkysulfonyl.