Patent ID: 8030497

Claim:
A compound of formula (I′) or a pharmaceutically acceptable salt thereof: wherein R′ 1 is selected from the group consisting of C 1 -C 6 alkyl, lower alkoxy-lower alkyl, lower thioalkyl-lower alkyl, cyclopropyl lower alkyl; R′ 2 is lower alkyl; R′ 3 is selected from the group consisting of halo, cyano, lower alkyl, lower alkoxy, lower thioalkyl, lower thioalkenyl, lower alkynyl, aryl and aryl-lower alkyl; R′ 4 is selected from the group consisting of H, halo, cyano, lower alkyl, aryl, aryl-lower alkyl, heteroaryl, heteroaryl-lower alkyl and the group having the formula R′ 8 —Z(CH 2 ) n —; wherein Z represents a direct bond or is selected from the group consisting of NH, CH 2 , CO, SO, SO 2 or S; wherein R′ 8 is selected from the group consisting of aryl, pyrazolyl, thiazolyl, cyclobutyl, tetrazolyl, pyridyl, indazolyl, pyrazinyl, furanyl, isoxazolyl, pyrrolidinyl, benzimidazolyl, imidazolyl, oxazolyl; and wherein n is 0, 1, 2 or 3; R′ 5 is H, halo, or lower alkyl; R′ 6 is lower alkoxy; and R′ 7 represents one or more substituents independently selected from the group consisting of H, halo, hydroxyl, lower alkyl, lower alkoxy, amino, cyano, and carbonyl.