Patent ID: 7723360

Claim:
A compound of general formula 1a, wherein R 1 is phenyl, optionally substituted with one, two or three R 2 ; R 2 are each independently —C 1-6 -alkyl, —C 3-6 -cycloalkyl, —C 1-6 -haloalkyl, —C 1-6 -aralkyl, halogen, —CN, —COOR 3 , —COR 3 , —CONR 3 R 4 , —NR 3 R 4 , —NR 3 COR 4 , —NR 3 SO 2 R 4 , —OR 3 , —NO 2 , —SR 3 , —SOR 3 , —SO 2 R 3 or —SO 2 NR 3 R 4 ; R 3 is H or —C 1-6 -alkyl; R 4 is H or —C 1-6 -alkyl; R 5 is —C 1-6 -alkyl R 6 are each independently —C 1-6 -alkyl, —C 1-6 -alkoxy, —C 1-6 -acyloxy, —C 1-6 -aralkyl, —C 3-6 -cycloalkyl, —C 1-6 -haloalkyl, —C 1-6 -thioalkyl, halogen, —OR 3 , —SR 3 , —CN, —NO 2 , —COOR 3 , —COR 3 , —CONR 3 R 4 , —NR 3 R 4 , —NR 3 COR 4 , —NR 3 SO 2 R 4 , —SOR 3 , —SO 2 R 3 , —SO 2 NR 3 R 4 , aryl or het; A is —C 2-8 -alkylene, optionally substituted with —C 1-3 -alkyl, halogen or —OH; B is aryl or het; Y is —CF 2 —, —NR 4 —, —O—, —S(O)—; n is 0, 1 or 2; m is 0, 1, 2, 3 or 4; and pharmaceutically acceptable salts thereof.