Patent ID: 8158390

Claim:
A method for increasing fermentative production of L-valine in a culture medium containing an L-valine-producing Coryneform bacterium , which comprises the step of transforming the L-valine-producing Coryneform bacterium by introducing therein a vector comprising at least one polynucleotide coding for transaminase C having SEQ ID NO: 2 from Corynebacterium glutamicum to obtain a recombinant L-valine-producing Coryneform bacterium having increased transaminase C activity over that of the corresponding wild-type L-valine-producing Coryneform bacterium through an increase in transaminase C gene expression, wherein the increased transaminase C gene expression of the transformed L-valine-producing Coryneform bacterium over the corresponding wild-type L-valine-producing Coryneform bacterium results from an exogenous increase in the gene copy count of polynucleotides coding for transaminase C from Corynebacterium glutamicum , and also from deactivation of pantothenate synthesis B (panB) and pantothenate synthesis C (panC) genes.