Patent ID: 7585877

Claim:
A compound represented by formula (I): or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: ring A, which comprises atoms Y 1 and Y 2 , is optionally substituted 8-azabicyclo[3.2.1]oct-8-yl R 1 is selected from the group consisting of cyano and nitro; Z 1 and Z 2 are each independently selected from the group consisting of optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted heterocyclyl, halogen, cyano, hydroxy, optionally substituted aminoalkyl, optionally substituted alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclylalkyl, optionally substituted heteroarylalkyl, —C(O)OR 4 , —C(O)NR 4 R 5 , —NHC(O)R 4 , —NHSO 2 R 4 , —CH═NOR 4 , CF 3 , —OC(O)R 4 , —OCR 4 , SR 4 , —S(O) n R 8 , and —SO 2 NR 8 R 9 ; R 4 and R 5 are each independently selected from the group consisting of hydrogen, alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, heterocyclylalkyl or substituted heterocyclylalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, heteroarylalkyl or substituted heteroarylalkyl, and heteroaryl or substituted heteroaryl; R 6 and R 7 are each independently selected from the group consisting of hydrogen, halo, cyano, hydroxy, alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, heterocyclylalkyl or substituted heterocyclylalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, heteroarylalkyl or substituted heteroarylalkyl, heteroaryl or substituted heteroaryl, OR 4 , NR 4 R 5 , SR 4 , C(O)R 4 , C(O)OR 4 , C(O)NR 4 R 5 , NHC(O)R 4 , NR 4 C(O)R 5 , OC(O)R 4 , C(S)R 4 , C(S)OR4, C(S)NR 4 R 5 , NHC(S)R 4 , OC(S)R 4 , S(O)R 4 , SO 2 NR 4 R 5 , OSO 2 R 4 , NHSO 2 R 4 , and alkyl substituted with OR 4 , NR 4 R 5 , SR 4 , C(O)R 4 , C(O)OR 4 , C(O)NR 4 R 5 , NHC(O)R 4 , NR 4 C(O)R 5 , OC(O)R 4 , C(S)R 4 , C(S)OR 4 , C(S)NR 4 R 5 , NHC(S)R 4 , OC(S)R 4 , S(O) n R 4 , SO 2 NR 4 R 5 , OSO 2 R 4 , or NHSO 2 R 4 ; R 8 and R 9 are each independently selected from the group consisting of hydrogen, alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, heterocyclylalkyl or substituted heterocyclylalkyl, arylalkyl or substituted arylalkyl, and heteroarylalkyl or substituted heteroarylalkyl; and n is an integer from 1 to 3.