Patent ID: 8283432

Claim:
A polymer formed by (a) reaction of a polyhydrosiloxane of general formula R 1 R 2 R 3 SiO—(SiR 4 R 5 —O) y (SiR 6 H—O) x (SiR 7 R 8 —O) z SiR 9 R 10 R 11 with a reactive compound to provide a functionalized polysiloxane, wherein the reactive compound comprises (1) a first reactive group, which is capable of reacting with an Si—H group, at one end, and (2) a second reactive group, which is capable of reacting with a fluoroquinolone antibiotic, at its other end; and the first reactive group comprises a vinylic group; and the second reactive group comprises an epoxy group or an anhydride group; (b) reaction of the functionalized polysiloxane with a fluoroquinolone antibiotic or a pharmaceutically acceptable salt thereof to provide a fluoroquinolone-functionalized polysiloxane; wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 8 , R 9 , R 10 , and R 11 are independently C 1 -C 20 alkyl, benzyl, tolyl, xylyl, or phenyl; R 7 is a C 1 -C 20 alkyl, benzyl, tolyl, xylyl, phenyl, texturizing moiety, a cross-linkable group, or a combination thereof; x is 1 to 100; y is 0 to 100; z is 0 to 100; at least one of y and z is greater than 0; and the polymer contains at least one fluoroquinolone group.