Patent ID: 8097278

Claim:
An oral dosage form comprising: (a) a first compartment comprising a medicament; (b) a second compartment comprising an inactivating agent; (c) a semi-permeable or permeable partition comprising a hexene film resin separating said first and second compartments; (d) an outer layer surrounding said first and second compartments; and (e) a third compartment comprising a detection material which is released when the dosage form is crushed or dissolved; wherein said partition is capable of being rendered impermeable upon exposure to a stimulus selected from the group consisting of heat, microwave radiation, infra-red radiation, visual radiation, ultraviolet radiation, and ionizing electromagnetic radiation, such that said partition that is rendered impermeable sequesters said medicament from said inactivating agent in the oral dosage form; wherein the detection material becomes visible upon being released when the dosage form is crushed or dissolved; and wherein said inactivating agent is selected from the group consisting of an indelible dye, a biological inactivating agent, a chemical inactivating agent, a denaturing inactivating agent, an electrical inactivating agent, a magnetic inactivating agent, a mechanical inactivating agent, a cross-linking agent, rat or human mu-opioid receptor, opioid neutralizing antibodies, a narcotic antagonist, irritating or dipphoric agents, an emetic, and a combination thereof.