Patent ID: 7482339

Claim:
A compound represented by the formula (I): wherein R 2 and R 3 are the same or different and each is C2-C4 alkyl, C2-C4 alkenyl, C1-C4 alkoxyC1-C4 alkyl, optionally substituted aminoC1-C4 alkyl, or C3-C6 cycloalkylC1-C4 alkyl; or R 2 and R 3 are taken together with the adjacent carbon atom to form an optionally substituted 5 to 8 membered non-aromatic carbocyclic ring or an optionally substituted 5 to 8 membered non-aromatic heterocyclic ring; R 4 is C1-C6 alkyl, hydroxyC1-C6alkyl, optionally substituted aminoC1-C6alkyl, or C1-C6 alkoxyC1-C6 alkyl; X is an oxygen atom or a sulfur atom; A is a group of the formula: wherein R 1 is, same or different, alkyl, alkoxy, alkylthio, optionally substituted amino, optionally substituted aryl, optionally substituted aryloxy, optionally substituted aralkyloxy, cycloalkyl, a halogen atom, hydroxy, nitro, haloalkyl, haloalkoxy, optionally substituted carbamoyl, carboxy, alkoxycarbonyl, alkylsulfinyl, alkylsulfonyl, alkoxylalkyl, alkylthioalkyl, optionally substituted aminoalkyl, alkoxyiminoalkyl, alkoxyalkoxy, alkylthioalkoxy, alkoxycarbonylalkoxy, carboxyalkoxy, alkylsulfonyloxy, optionally substituted heteroaryl, an optionally substituted non-aromatic heterocyclic group, cyano, cyanoalkoxy, or a group of the formula: —C(═O)—R H wherein R H is a hydrogen atom, alkyl, optionally substituted aryl, or an optionally substituted non-aromatic heterocyclic group; W is —CH 2 CH 2 CH 2 —, —CH 2 CH 2 CH 2 CH 2 —, —OCH 2 O—, —OCH 2 CH 2 O—, —N(CH 3 )CH 2 CH 2 CH 2 —, or —CH═CH—CH═CH—; n is an integer of 0 to 7; wherein the optionally substituted amino is non-substituted amino, C1-C4 alkylamino, (C1-C4 alkyl)carbonylamino, aryl carbonylamino, N—(C1-C4 alkyl)carbonyl-C1-C4 alkylamino, aralkylamino, C1-C4 alkylsulfonylamino, C2-C4 alkenyloxycarbonylamino, (C1-C4 alkoxy)carbonylamino, C2-C4 alkenylamino, arylcarbonylamino, or heteroarylcarbonylamino, the substituent of optionally substituted carbamoyl is selected from the group consisting of alkyl and acyl, and, the substituent of non-aromatic carbocyclic ring, non-aromatic heterocyclic ring, aryl, aryloxy, aralkyloxy, heteroaryl, and a non-aromatic heterocyclic group is selected from the group consisting of hydroxy, carboxy, a halogen atom, haloalkyl, haloalkoxy, alkyl, alkenyl, formyl, acyl, alkynyl, cycloalkyl, alkoxy, alkoxycarbonyl, nitro, nitroso, oxo, optionally substituted amino, azido, aryl, aryloxy, cyano, isocyano, isocyanato, thiocyanato, isothiocyanato, mercapto, alkylthio, alkylsulfonyl, arylsulfonyl, optionally substituted carbamoyl, sulfamoyl, formyloxy, haloformyl, oxalo, thioformyl, thiocarboxy, dithiocarboxy, thiocarbamoyl, sulfino, sulfo, sulfoamino, hydrazino, ureido, amidino, guanidino, formyloxy, thioxo, alkoxyalkoxy, and alkylthioalkoxy, a pharmaceutically acceptable salt thereof.