Patent ID: 8623397

Claim:
A delivery device, comprising: a hollow container; a plurality of solid polymeric layers established in the container, wherein the solid polymeric layers chosen from poly(lactide-co-glycolide) (PLGA); polyglycolic acid (PGA); poly(L-lactic acid) (PLLA); polyanhydrides; poly(ortho ethers); polycaprolactone; poly(hydroxy butyrate); poly(phosphoesters); poly(propylene fumarate); polyphosphazenes; polycarbonates; polyurethane; copolymers thereof; a copolymer of a sebacic acid anhydride precursor, a 1,3-bis(carboxyphenoxy) propane anhydride precursor, and a poly(ethylene glycol) anhydride precursor; and combinations thereof; and a solid layer including a film forming material and a predetermined substance incorporated into the film forming material, the solid layer being established between each of the plurality of solid polymeric layers, the film forming material being chosen from alginate; polyethylene glycol; collagen; gelatin; hyaluronic acid; starch; glycogen; cellulose; caragena; dextran; chitin; chitosan; pectin; heparan; heparan sulfate; and combinations thereof; whereby degradation of the solid polymeric layers and release of the predetermined substance occur intermittently wherein the surface area of the solid layer in contact with the solid polymeric layer is smaller than the surface area of the solid polymeric layer such that a gap exists between the plurality of solid polymeric layers at an outer edge of the solid layer; and the delivery device further includes a sealant material introduced into the gap.