Patent ID: 7939521

Claim:
An (R)-2 aryl-propionamide compound of formula (I): wherein Ar is a phenyl group substituted at the 3 (meta) position by a group R 1 selected from: a linear or branched C 1 -C 8 -alkanoyl, C 1 -C 6 -cycloalkanoyl, 2-furyl, 2-oxazolyl, 3-isoxazolyl, 2-benzoxazolyl, 3-benzoisoxazolyl, 2-thiazolyl, 2-pyridyl, furancarbonyl, benzofurancarbonyl, thiophencarbonyl, pyridinecarbonyl, benzolamino carbonyl, C 1 -C 6 -aclamino, benzoylamino, aryloxy or arylamino group, or R 1 forms a fused bicyclic system selected from 3-4-dihydro-1H-quinolyl-2-one, 1,3-dihydro-indol-2-one and 1,3,4,5-tetrahydrobenzo[b]azepin-2-one; R is selected from: H, OH, C 1 -C 5 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 5 -alkenyl, C 1 -C 5 -alkoxy; an heteroaryl group selected from pyridine, pyrimidine, pyrrole, thiofene, furane, indole, thiazole, oxazole; an α or β carboxyalkyl group consisting of straight or branched C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 6 -alkenyl, C 1 -C 6 -phenylalkyl, optionally substituted with a further carboxy (COOH) group; or a group of formula SO 2 Rd wherein Rd is C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 6 -alkenyl, aryl, heteroaryl, with the proviso that compounds of general formula (I) are not: (R)-2-(3-phenoxyphenyl)-propanoyl-phenylglycine; (R)-2-(3-phenoxyphenyl)-propanoyl-glycine; or (R)(-)-2-[(3′-acetyl)phenyl]-N-(4″-pyrimidyl)propionamide.