Patent ID: 7384913

Claim:
A method for inducing oocyte activation, the method comprising contacting an oocyte with an effective amount of (a) an isolated polypeptide comprising: 1) at least one of (i) the sequence PPPGY (SEQ ID NO: 1), and (ii) the sequence LPPAY (SEQ ID NO:2), and 2) at least three domains, each domain comprising the sequence YGXPPXG (SEQ ID NO:3), wherein Y represents a Tyrosine residue, G represents a Glycine residue, L represents a Leucine residue, A represents an Alanine residue, X represents any amino acid residue, and P represents a Proline residue, said isolated polypeptide comprising an amino acid sequence having at least 75% sequence identity to the sequence of SEQ ID NO:5 or SEQ ID NO:12, and (b) globozoospermic sperm, round spermatids, or sperm, wherein said oocyte is activated.