Patent ID: 8729268

Claim:
A compound of Formula (I): or pharmaceutically acceptable salts thereof, wherein, D is selected from the group consisting of an aromatic, heteroaromatic, cycloalkyl or heterocyclic ring system, each of which is substituted with 1 to 5 independently selected R 38 ; M is wherein * represents the point of attachment to D; and † represents the point of attachment to Z; Z is —O—; Ar is a 5 to 7 membered aromatic ring system, which is optionally substituted with 0 to 4 R 2 groups; and G is selected from the group consisting of wherein each R 38 is —C 1 -C 6 alkyl-heterocycle, wherein said heterocycle is optionally substituted with halo, hydroxy, oxo, nitro, halohydrocarbyl, hydrocarbyl, alkyl, cycloalkyl, heterocyclyl, aryl, heteroaryl, aralkyl, alkoxy, aryloxy, amino, acylamino, alkylcarbamoyl, arylcarbamoyl, aminoalkyl, acyl, carboxy, hydroxyalkyl, alkanesulfonyl, arenesulfonyl, alkanesulfonamido, arenesulfonamido, aralkylsulfonamido, alkylcarbonyl, acyloxy, cyano, and ureido groups, and; R 2 at each occurrence is independently selected from —H and halogen; each R 3 is independently selected from the group consisting of —H and R 4 ; R 4 is (C 1 -C 6 )alkyl; each R 13 is independently selected from the group consisting of —H, —C(O)NR 3 R 3 and C 1 -C 6 alkyl; Q is a three- to ten-membered ring system, optionally substituted with between zero and four of R 20 ; each R 20 is independently selected from the group consisting of —H, halogen, trihalomethyl, —OR 3 , —S(O) 0-2 R 3 , —S(O) 2 NR 3 R 3 , —C(O)OR 3 , —C(O)NR 3 R 3 , —(CH 2 ) 0-5 (heteroaryl), C 1 -C 6 alkyl, —(CH 2 ) n P(═O)(C 1 -C 6 alkyl) 2 , wherein n is an integer ranging from 0 to 6.