Patent ID: 7598284

Claim:
A compound of the formula (I-Indazole): or a salt thereof, wherein R 1 represents a hydrogen atom, a hydroxyl group or a halogen atom; R 2 represents NHSO 2 R 3 or SO 2 NR 4 R 4′ ; R 3 represents a (C 1 -C 6 )alkyl group, a benzyl group, a phenyl group or NR 4 R 4′ ; R 4 and R 4′ may be the same or different and each independently represents a hydrogen atom or a (C 1 -C 6 )alkyl group; R 5 represents a hydrogen atom or a (C 1 -C 6 )alkyl group; R 7 represents a hydrogen atom, a (C 1 -C 6 )alkyl group, a (C 1 -C 6 )alkyl group optionally substituted with one or more halogen atoms, an optionally substituted —(CH 2 ) n -phenyl group, —CH═CH—CO 2 R 5 or —(CH 2 ) n —R 8 ; R 8 represents OR 5 , CN, NR 41 R 41′ , CO 2 R 5 , SO 3 R 5 , SO 2 (C 1 -C 6 )alkyl, SO 2 NR 41 R 41′ , C(═O)R 5 , C(═O)NR 41 R 41′ or NR 51 COR 5 , wherein R 5 is as defined above; R 51 represents a hydrogen atom or a (C 1 -C 6 )alkyl group; R 41 and R 41′ may be the same or different and each independently represents a hydrogen atom, a (C 1 -C 6 )alkyl group or a (C 3 -C 6 )cycloalkyl group, or R 41 and R 41′ taken together represent a (C 2 -C 6 )alkylene group; or R 8 is a heterocycle selected from pyridyl, pyrimidinyl, pyrazinyl, thiazolyl, oxazolyl, imidazolyl, triazolyl, 1,2,4-oxadiazolyl, isoxazolyl, tetrazolyl, pyrazolyl, hexamethyleneiminyl, piperidinyl and pyrrolidinyl, wherein one of the ring nitrogen atoms of imidazolyl, triazolyl and tetrazolyl may be optionally substituted with a (C 1 -C 6 )alkyl group which is optionally substituted with one or more halogen atoms; wherein with respect to one or more of the ring carbon atoms of the each heterocycle, each of them may be optionally substituted with one or more substituents which are independently selected from hydrogen, a (C 1 -C 6 )alkyl group optionally substituted with one or more halogen atoms, a halogen atom, nitro, cyano and —(CH 2 ) n —R 9 ; and wherein the ring nitrogen atom of hexamethyleneiminyl, piperidinyl and pyrrolidinyl may be substituted with a (C 1 -C 6 )alkyl group, a (C 3 -C 6 )cycloalkyl group, COR 5 , COOR 5 , CONR 4 R 4′ or SO 2 R 5 ; R 9 represents NR 4 R 4′ , CO 2 R 5 , C (═O)—NR 4 R 4′ , OR 5 , SO 3 R 5 , SO 2 (C 1 -C 6 )alkyl or SO 2 NR 4 R 4′ , wherein R 5 , R 4 and R 4′ are as defined above; Y represents an oxygen atom, NH, a sulfur atom or a methylene group; R 10 represents a hydrogen atom, an optionally substituted —(CH 2 ) n -phenyl group, a —(C 1 -C 10 )alkyl group or —(CH 2 ) n —R 8 , wherein R 8 is as defined above; n is an integer of 0 to 6; *1 represents an asymmetric carbon atom; and *2 represents an asymmetric carbon atom when R 5 is other than a hydrogen atom.