Patent ID: 7553836

Claim:
A compound of Formula I wherein A is mono-cyclic aryl; D is selected from the group consisting of a direct bond, alkyl, cycloalkyl and heterocyclyl; Q is selected from the group consisting of —(CR 8 R 9 ) n — and —CR 8 ═CR 9 —; W is selected from the group consisting of a direct bond, —C(O)—, —O—, —N(R 9a )—, —S(O)—, —S(O 2 )—, —S(O 2 )N(R 9a )— and —C(R 10 )(R 11 )—; R 1a , and R 1c are independently selected from the group consisting of hydrogen, halo, aryl, aryloxy, arylthio, arylalkylthio, and heteroaryl, wherein aryl and heteroaryl, alone or as part of another group, may optionally and independently, be substituted with 1-3 R 4 ; R 1b is aryl which may be optionally substituted with 1-3 R 4 ; R 2 is selected from the group consisting of hydroxyl, lower alkoxy, hydroxyalkyl, cycloalkoxy, OCONR 7 R 7a , CN, CONR 7 R 7a , SOR 6 , SO 2 R 6 , NR 7 COR 7b , NR 7 CO 2 R 7b , CO 2 R 6 , heterocyclyl, heteroaryl, NR 7 R 7a , NR 7 SO 2 R 6 and COR 6 ; R 3 is selected from the group consisting of hydrogen, hydroxyl, alkoxy, halo, CN, alkyl, perfluoroalkyl, cycloalkyl and cycloalkoxy, wherein R 3 and D may optionally be taken together with the atoms to which they are attached to form a 5 to 7-membered ring; R 4 is selected from the group consisting of alkyl, halo, polyfluoroalkyl, alkoxy, polyfluoroalkyloxy, CN and alkylthio; R 6 is independently selected from the group consisting of lower alkyl and lower cycloalkyl; and R 7 , R 7a and R 7b are independently selected from the group consisting of hydrogen, lower alkyl and lower cycloalkyl, wherein two R 7 groups and the atom to which they are attached may optionally form a heterocyclyl of 4 to 7 atoms; R 8 , R 9 , and R 9a , R 10 and R 11 are independently selected from the group consisting of hydrogen and alkyl; n is 2; or a pharmaceutically acceptable salt thereof; a stereoisomer thereof; or a prodrug ester thereof.