Patent ID: 8716285

Claim:
A compound of formula (I) wherein X is —CH 2 —, oxygen or —NR 4 ; R 1 is hydrogen or halogen; R 2 is hydrogen; or alkyl, provided that X is —CH 2 — or oxygen; R 3 is phenyl, unsubstituted or once or twice substituted by halogen, nitro, alkyl, trifluoromethyl, dialkylamino, aminoalkyl, cyano or phenoxy; pyridin-2-yl, unsubstituted or once or twice substituted by nitro or trifluoromethyl; pyrimidin-2-yl, unsubstituted or once or twice substituted by alkyl, trifluoromethyl, alkoxy, phenoxy, pyridinyl, alkylpyridinyl, alkoxypyridinyl, halopyridinyl, morpholinylpyridinyl, naphthyl, quinolinyl, phenyl or substituted phenyl, wherein substituted phenyl is phenyl once or twice substituted by alkyl, halogen, dialkylamino, nitro, alkoxy, trifluoromethyl or phenoxy; quinazolin-2-yl, unsubstituted or once or twice substituted by halogen; phenylalkenylcarbonyl; phenylalkylcarbonyl; phenylalkoxycarbonyl; phenylcarbonyl, unsubstituted or once or twice substituted by halogen, alkyl, trifluoromethyl, alkoxy, trifluoromethoxy, cyano, dialkylamino or phenyl; pyridinylalkenylcarbonyl; pyridinylalkylcarbonyl; pyridinylalkoxycarbonyl; alkylsulfonyl; phenylsulfonyl, wherein phenyl is unsubstituted or once or twice substituted by halogen, trifluoromethyl, trifluoromethoxy, alkoxy, cyano, dialkylamino or dialkylaminoalkyl; or pyridinylsulfonyl; R 4 is hydrogen or alkyl; or a pharmaceutically acceptable salt, ester or stereoisomers thereof.