Patent ID: 8902306

Claim:
A method for detecting a cell state, comprising: sequentially obtaining first image data and second image data for a cell under observation by using an imaging device at a predetermined time interval; aligning rotation angle orientations corresponding to the first and second image data for the cell under observation, the rotation angle orientations being obtained by calculating the rotation angles of axes passing through the centroid of the cell under observation in order to align the orientations on the image plane of the cell under observation when the first image data is obtained and the cell under observation when the second image data is obtained; extracting a variation amount between an intracellular texture feature value of the cell under observation in the first image data and an intracellular texture feature value of the cell under observation in the second image data, the rotation angle orientations being aligned; and detecting a degree of activity of the cell under observation on the basis of a time series variation of the extracted variation amount.