Patent ID: 8461169

Claim:
A method for treating a subject suffering from disease or condition mediated by an increase in c-kit and/or c-fms kinase activity, said method comprising administering to the subject an effective amount of a compound of Formula III, or a salt, prodrug, tautomer, or stereoisomer thereof, wherein: L 4 is —CH 2 —, or —C(O)—; R 81 is selected from the group consisting of hydrogen, —CN, fluoro, chloro, lower alkyl, fluoro substituted lower alkyl, lower alkoxy, and fluoro substituted lower alkoxy; R 82 is hydrogen; R 83 is nitrogen containing heteroaryl, wherein nitrogen containing heteroaryl is optionally substituted with one or two substituents selected from the group consisting of halogen, lower alkyl, fluoro substituted lower alkyl, cycloalkylamino, —NHR 41 , —NR 41 R 41 , —OR 41 and —S(O) 2 R 41 ; and R 41 at each occurrence is lower alkyl or cycloalkyl, wherein lower alkyl is optionally substituted with one or more fluoro.