Patent ID: 7259166

Claim:
A compound according to formula I: wherein R 1 and R 2 are independently hydrogen, halo, amino, hydroxyamino, cyano, nitro, lower alkyl, —OR 5 , perfluoro-lower alkyl, lower alkyl thio, perfluoro-lower alkyl thio, lower alkyl sulfonyl, perfluoro-lower alkyl sulfonyl, lower alkyl sulfinyl, or sulfonamido; R 3 is an unbranched heteroalkyl chain of 3-4 carbon atoms plus one oxygen or sulfur atom, wherein the chain, in combination with the carbon atom it is bonded to, forms a five- or six-membered ring, and when the chain contains an O heteroatom, the chain is unsubstituted, and when the chain contains an S heteroatom, the chain is unsubstituted or the S heteroatom member of the chain is substituted by an oxo group; R 4 is an unsubstituted or mono-substituted five- or six-membered heteroaromatic ring connected by a ring carbon atom to the amine group shown, which five- or six-membered heteroaromatic ring contains from 1 to 3 heteroatoms selected from sulfur, oxygen or nitrogen, with one heteroatom being nitrogen which is adjacent to the connecting ring carbon atom; said mono-substituted heteroaromatic ring being mono-substituted at a position on a ring carbon atom other than adjacent to said connecting carbon atom with a substituent selected from the group consisting of lower alkyl, halo, nitro, cyano, perfluoro-lower alkyl, amidooxime, n is 0, 1, 2, 3 or 4; R 5 is hydrogen, lower alkyl, or perfluoro-lower alkyl; R 6 is lower alkyl; and R 7 is hydrogen or lower alkyl; * denotes a carbon atom that is asymmetric in all or most of the compounds of formula I; or a pharmaceutically acceptable salt thereof.