Patent ID: 7858110

Claim:
A method of delivering one or more active ingredients to a subject, comprising: implanting an implantable device into the subject, in which the implantable device comprises a polyurethane-based polymer having polyether-based polyol segments represented by the formula O—(CH 2 —CH 2 —CH 2 —CH 2 ) x —O— whereby an increase in “x” represents a decrease in Flex Modulus, said polyurethane-based polymer configured to provide a cylindrically shaped reservoir, wherein the reservoir is sealed after being charged with an effective amount of solid formulation comprising one or more active ingredients exhibiting hydrophobic characteristics, such that the release of the one or more active ingredients at a substantially zero order rate in vitro by diffusion through the polyurethane-based polymer generally increases with the selection of the polyurethane-based polymers of decreasing Flex Modulus.