Patent ID: 7659062

Claim:
A method of detecting uterine serous papillary carcinoma in a human individual, comprising the steps of: examining gene expression levels of a group of genes comprising ERBB2, PROML1, SFRP1, STC1, F2R, MEN1, TAC1, SLC1A1, KIAA0918, AF038169, HRASLS3, UGT2B7, PTGER2, GRB7, INHBB, SLC6A12, MUC4, CSPG5, PDZK1, RLN2, PKIA, QPRT, PTPRM, PSPHL, PTPRM, AKAP2, RAGD, KIAA1157, PADI2, CCNE1, GGT2, PAX8, GPC4, MYO7A, TJP3, UCHL1, INPP4B, PLAGL1, TMEFF1, IDI1, NEU1, DMD, TUBB, SDC2, ZNF91, INA, TP53BP2, ELKS, FLJ13612, DKFZP566A1524, SLC25A1, ACO1, LOC51760, BNIP3L, CDH1, HIVEP2, API5, NEK2, ARSDR1, CPO, PRRG1, PAX8, PIK3C2B, KIAA0790, CDKN2A, KRTHB1, SAA1, KRT7, TFAP2A, MAP17, LCN2, EEF1A2, L1CAM, VGLL1, GAL, KLK10, IL6, MAL, PI3, PTTG1, WNT7A, CST6, CDC20, KRTHA4, KLK6, CCNE1, KIF2C, KIBRA, UBE2C, CLDN4, DKK1, TNNT1, BIK, CRABP1, STK6, NMU, TPX2, HIST1H1C, IL18, TNNI3, TTK, MICB, SPOCK2, SLC7A5, KRT18, BF, PDXK, RAI3, LAMP3, HMGA1, WNT7A, LAMB3, CENPA, BUB1, ITGA3, CCNE1, CLDN3, RAI3, CCNB1, ANXA2, TK1, FOXM1, TNIP1, CCNB2, F2RL1, TGFA, CCNB1, ANXA3, ITPR3, CDA, EPHB2, PRSS8, PLAUR, FOXD1, CA2, AD024, SPINT2, WFDC2, LAMC2, KIFC1, TRIM16, CDC6, CLDN7, CCNA2, TM4SF11, ESPL1, GALNT3, IL8, KIAA0746, B3GNT3, G1P2, SCNN1A, HMMR, TNFAIP2, TRIP13, PMAIP1, ETV4, MAPK13, CKS1B, NFE2L3, TOP2A, EXO1, SLC16A3, PLK, MYBL2, KPNA2, LAD1, TOP2A, IRAK1, GALE, ITGB8, IMP-3, VAMP8, SERPINB8, INA, BUB1B, ERBB3, SLPI, E2-EPF, FEN1, PPFIA1, KIF11, TK1, C1orf38, EFNA1, CIT, EPHA1, and STAT1 in a uterine sample from the human; and performing statistical analysis on the expression levels of said genes in the uterine sample as compared to expression levels thereof in ovarian tumor samples from individuals with ovarian serous papillary carcinoma, wherein overexpression of said genes compared to expression levels thereof in the individuals with ovarian serous papillary carcinoma, indicates that said individual has uterine serous papillary carcinoma.