Patent ID: 8048878

Claim:
A compound represented by the formula (1): or a pharmacologically acceptable salt thereof, wherein represents a single bond or a double bond; Ar 1 represents a phenyl group that is optionally substituted with 1 to 3 substituents selected from Substituent Group A1 or a pyridinyl group that is optionally substituted with 1 to 3 substituents selected from Substituent Group A1; R 1 and R 2 are the same or different and each represent a group selected from the following Substituent Group A1; Z 1 represents a methylene group or vinylene group, which n optionally substituted with 1 or 2 substituents selected from Substituent Group A1, an oxygen atom, or an imino group that is optionally substituted with a substituent selected from Substituent Group A1; and p, q, and r are each an integer of 1; Substituent Group A1: (1) a halogen atom, (2) a hydroxyl group, (3) a cyano group, (4) a C3-8 cycloalkyl group, (5) a C3-8 cycloalkoxy group, (6) a C1-6 alkyl group, wherein the C1-6 alkyl group may be substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, hydroxyl group, cyano group, C3-8 cycloalkyl group, C1-6 alkoxy group, and C3-8 cycloalkoxy group, (7) a C1-6 alkoxy group, wherein the C1-6-alkoxy group is optionally substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, hydroxyl group, cyano group, C3-8 cycloalkyl group, and C3-8 cycloalkoxy group, (8) an amino group that is optionally substituted with one or two C1-6 alkyl groups, wherein the C1-6 alkyl groups is optionally substituted with 1 to 3 halogen atoms, (9) a carbamoyl group that is optionally substituted with one of two C1-6 alkyl groups, wherein the C1-6 alkyl groups is optionally substituted with 1 to 3 halogen atoms, (10) a carboxyl group, (11) a C1-6 alkoxycarbonyl group, wherein the C1-6 alkoxy group is optionally substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, hydroxyl group, cyano group, C3-8 cycloalkyl group, and C3-8 cycloalkoxy group, (12) a C1-6 alkyl group (13) a C1-6 alkylsulfonyl group, and (14) a hydrogen atom.