Patent ID: 8748621

Claim:
A method for treating, ameliorating, or controlling a central nervous system disorder in a human, selected from the group consisting of anxiety disorders, psychotic disorders selected from the group consisting of schizophrenia, schizoaffective disorder and schizophreniform disorder, mood disorders, epilepsy or convulsive disorders, and dementia of the Alzheimer's type, wherein the method comprises administering to the human an effective amount of a compound having the formula (I) or a stereochemically isomeric form thereof, wherein R 1 is C 1-6 alkyl; or C 1-3 alkyl substituted with C 3-7 cycloalkyl, phenyl, or phenyl substituted with halo, trifluoromethyl or trifluoromethoxy; R 2 is halo, trifluoromethyl, C 1-3 alkyl or cyclopropyl; R 3 is hydrogen or halo; X is O, S, SO, SO 2 , or CF 2 ; and Ar is unsubstituted phenyl; unsubstituted pyridinyl; or phenyl or pyridinyl substituted with one or two substituents selected from the group consisting of halo, C 1-3 alkyl, C 1-3 alkoxy, trifluoromethyl, hydroxyC 1-3 alkyl and (CH 2 ) n —CO 2 H, wherein n=0, 1, or 2; or a pharmaceutically acceptable salt thereof, provided that when R 3 is 2′-fluoro then Ar is not 3-pyridinyl substituted with one or two C 1-3 alkyl substituents.