Patent ID: 8569256

Claim:
A cationic lipid of Formula I having the following structure: or salts thereof, wherein: R 1 and R 2 are either the same or different and are independently an optionally substituted C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl, or R 1 and R 2 may join to form an optionally substituted heterocyclic ring of 4 to 6 carbon atoms and 1 or 2 heteroatoms selected from the group consisting of nitrogen (N), oxygen (O), and mixtures thereof; R 3 is either absent or is hydrogen (H) or a C 1 -C 6 alkyl to provide a quaternary amine; R 4 and R 5 are either absent or present and when present are either the same or different and are independently an optionally substituted C 1 -C 10 alkyl or C 2 -C 10 alkenyl; and n is 0, 1, 2, 3, or 4.