Patent ID: 8785445

Claim:
A compound of general formula (I) or a pharmaceutically acceptable salt thereof, wherein: A is H, CN, Cl, F, cyclopropyl, (1-4 C)alkyl or OMe; A 1 is H, Cl, Br, F, cyclopropyl, (1-4 C)alkyl or OMe; R 1 is —W-L 1 -hetAr 1 ; W is —CONR 3a — or —NR 3b CO—; R 3a and R 3b are each H or methyl; L 1 is a —(CR a R b ) n — or n is 0 or 2; R a and R b are independently H, F, methyl, or cyclopropyl, or R a and R b together with the carbon to which they are attached form a cyclopropyl ring; hetAr 1 is heteroaryl ring having the structure: wherein m is 0 or 1 and said heteroaryl ring is optionally substituted with one or more R c substituents, zero or one of D 4 , D 5 and D 6 is N, the remainder being CH; each R c is independently selected from halogen, CF 3 , (1-6C)alkyl, —O(1-6C alkyl), cyclopropyl, —O—(CH 2 CH 2 )OMe, —S(1-6C alkyl), di(1-6C alkyl)amino, and a 5-6 membered azacycle; Ar is phenyl optionally substituted with one or more R d substituents; each R d is independently selected from (1-6C)alkyl, —O(1-6C)alkyl, halogen, —S(1-6C alkyl), and CF 3 , or two adjacent R d substituents together with the atoms to which they are attached form a 5-6 membered oxacyclic ring; R 7a , R 7b and R 8 are independently H or methyl; and R 10 is H, Me or NH 2 .