Patent ID: 8258158

Claim:
A compound of formula (I), wherein R 1 is selected from the group consisting of: dimethylpropyl, dimethylbutyl, cyclopropylalkyl, pyrazolyl, methyl-trifluoromethyl-1H-pyrazolyl, morpholinyl, phenyl, 2-chlorophenyl, 4-methylphenyl and 4-methoxyphenyl; R 2 is selected from the group consisting of: hydrogen, alkyl, hydroxyalkyl and alkoxyalkyl; R 3 is selected from the group consisting of: hydrogen, alkyl, hydroxyalkyl and alkoxyalkyl; R 4 is selected from the group consisting of: hydrogen, halogen, alkyl, hydroxyalkyl and alkoxyalkyl; R 5 is hydrogen or alkyl; R 6 is selected from the group consisting of: 2,3-dihydro-benzofuranyl, alkylpyridin-3-yl, haloalkoxypyridin-3yl, pyridazinyl, alkoxypyridazinyl, alkyl-trifluoromethyl-1H-pyrazolyl, phenyl and substituted phenyl, wherein substituted phenyl is phenyl substituted in the 4-position with a substituent selected from the group consisting of: chlorine, isopropyl, hydroxyalkyl, isopropoxy, cycloalkylalkoxy, haloalkoxy, haloalkoxyalkyl, alkoxycarbonylalkoxy, carboxyalkoxy, hydroxyalkoxy, alkoxyhaloalkoxy and hydroxyhaloalkoxy; and optionally further substituted in another position with one substituent independently selected from the group consisting of: fluorine, trifluoromethoxy, alkoxycarbonylalkoxy and hydroxyalkoxycarbonyl; A 1 is carbonyl or —S(O) 2 —; A 2 is a single bond, —CH 2 CH 2 — or G; n is zero, 1, 2, 3, 4 or 5; and pharmaceutically acceptable salts thereof; with the proviso that, when R 6 is phenyl or phenyl substituted in the 4-position with chlorine, A 2 is G; with the further proviso that said compound is not 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide; 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid [2-(4-difluoromethoxy-phenyl)-ethyl]-amide; 1-benzenesulfonyl-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide; 1-benzenesulfonyl-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-difluoromethoxy-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-chloro-2-fluoro-phenyl)-amide; 1-benzoyl-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(2-chloro-benzoyl)-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-benzenesulfonyl-piperidine-4-carboxylic acid (1-phenyl-cyclopropylmethyl)-amide or 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid (1-phenyl-cyclopentylmethyl)-amide.