Patent ID: 8637260

Claim:
A method for detecting the presence of a polypeptide comprising SEQ ID NO: 9 in a subject, wherein the polypeptide is phosphorylated at one or both of Ser183 and Ser194, the method comprising: (a) providing a biological sample; (b) contacting the biological sample with an antibody or antigen binding portion thereof, wherein the antibody: i) binds to a polypeptide consisting of SEQ ID NO: 9 (RalA) that is phosphorylated at one or both of Ser183 and Ser194; and ii) does not bind to a polypeptide consisting of SEQ ID NO:9 that is not phosphorylated at Ser183 and is not phosphorylated at Ser194; and (c) detecting the presence or absence of a polypeptide comprising SEQ ID NO: 9, that is phosphorylated at one or both of Ser183 and Ser194 bound to the antibody or antigen binding portion thereof.