Patent ID: 8513250

Claim:
An imidazolo-heteroaryl derivative of formula (I) wherein, Y=N and W is C or Y=C and W=N, R1 is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, CO 2 R a , COR a , CONR a R b ; CR a ═NOR b , S(O) n R a , phenyl or heterocycle, all being optionally substituted by one or several identical or different R, or R1 is H, halogen or CN; R 2 is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl OR a , S(O) n R a , phenyl or heterocycle, all being optionally substituted by one or several identical or different R, or R2 is H or halogen; R 3 is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, CO 2 R a , COR a , CR a , NR a R b , NR a COR b , CONR a R b , CR a ═NOR b , S(O) n R a , SO 2 NR a R b , phenyl or heterocycle, all being optionally substituted by one or several identical or different R, or R3 is H, halogen or CN; R4 is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, phenyl or heterocycle all being optionally substituted by one or several identical or different R, or R4 is H, halogen or CN; R5 is H, COR a , CO 2 R a , P(O)(OH) 2 or COCHR a NR b R c ; R a , R b and R c identical or different are selected from the group consisting of H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, phenyl and heterocycle; R is selected from the group consisting of C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, phenyl, heterocycle, CO 2 R a , COR a , CONR a R b , OCOR a , OR a , NR a R b , CR a ═NOR b , NR a CORb, NR a COOR b , OCONR a R b , NR a CONR b R c , NR a SO 2 R b , S(O) n R a , and SO 2 NR a R b , all being optionally substituted by one or several identical or different R′, or R is halogen; CN or NO 2 , Ra, Rb and Rc are such as described above; R′ is selected from the group consisting of C 1 -C 10 alkyl, CO 2 R″, COR″, C0NR″R′″, OCOR″, OR″, NR″R″OR″═NOR″NR″COR′″, NR″COOR′″, OCONR″R′″, NR″C0NR″R″NR″SO 2 R″S(O) n R″, SO 2 NR″R″ halogen, CN and NO 2 ; R″ and R′″ being identical or different are H or C 1 -C 10 alkyl or form together a 3 to 6 membered nitrogenous heterocycle; n is 0, 1 or 2; with the proviso that R5 is not H, when R2=F or SO 2 CH 3 ; R1, R3 and R4=H; and W=C, and with the proviso that R1, R2, R3, R4 and R5 are not all H when W is C and Y is N, or a pharmaceutically acceptable salt thereof.