Patent ID: 8071636

Claim:
A method of treating a condition or disease alleviated by activation of Î±-adrenergic receptors in a mammal comprising: administering a compound having a structure wherein R 1 and R 2 are each independently selected from hydrogen, C 1-4 alkyl, C 1-4 alkoxy, OH, halogen, NRâ€² 2 , CN, CO 2 Râ€², C(O)NRâ€²Râ€³, alcohol, C 1-4 halogenated alkyl, C 1-4 halogenated alkoxy, and substituted or unsubstituted aryl or heteroaryl; Râ€² is selected from hydrogen, C 1-4 alkyl and C 1-4 halogenated alkyl, substituted or unsubstituted aryl or heteroaryl; Râ€³ is selected from hydrogen and C 1-4 alkyl, substituted or unsubstituted aryl or heteroaryl; and wherein said compound activates at least one of said Î±-adrenergic receptors; wherein said condition or disease is selected from the group consisting of pain, visceral pain, corneal pain, headache pain, cancer pain, back pain, irritable bowel syndrome pain, muscle pain, or pain associated with diabetic neuropathy.