Patent ID: 8106039

Claim:
A compound of formula I or a pharmaceutically acceptable salt thereof, wherein: X 1 , X 2 , X 3 , X 4 , X 5 , and X 6 are each independently N, C, S, O, B, or Si; R 1 and R 2 are taken together to form a mono-, bi- or tricyclic, carbo- or heterocyclic ring, wherein the ring is either unsubstituted or substituted in one or more position(s) with halo, hydroxyl, carbonyl, nitro, amino, trihaloalkyl, substituted or unsubstituted C 1 -C 4 alkoxy, substituted or unsubstituted straight or branched C 1 -C 6 alkyl-OH, substituted or unsubstituted straight or branched C 1 -C 6 alkyl-NH 2 , C 1 -C 4 alkenyloxy, aryl, aralkyl, phenoxy, benzyloxy, or any other hydrogen bond donor or acceptor, wherein the individual ring size for a monocyclic ring is 5-7 members and for a bicyclic or tricyclic ring is 3-8 members, and wherein a heterocyclic ring contains 1-5 heteroatom(s) selected from the group consisting of O, N, and S; R 3 and R 4 are taken together to form a mono-, bi- or tricyclic, carbo-, or heterocyclic ring, wherein the ring is either unsubstituted or substituted in one or more position(s) with halo, hydroxyl, carbonyl, nitro, amino, trihaloalkyl, substituted or unsubstituted C 1 -C 4 alkoxy, substituted or unsubstituted straight or branched C 1 -C 6 alkyl-OH, substituted or unsubstituted straight or branched C 1 -C 6 alkyl-NH 2 , C 1 -C 4 alkenyloxy, aryl, aralkyl, phenoxy, benzyloxy, or any other hydrogen bond donor or acceptor, wherein the individual ring size for a monocyclic ring is 5-7 members and for a bicyclic or tricyclic ring is 3-8 members, and wherein a heterocyclic ring contains 1-5 heteroatom(s) selected from the group consisting of O, N, and S; M is Ru, Pt, Tc, Re, Os, Rh, Ir, Pd, Au, Cu, Fe, Co, or Cr; Q is straight or branched chain C 1 -C 6 alkyl or alkenyl, optionally substituted with halo, hydroxyl, nitro, trifluoromethyl, C 1 -C 4 straight or branched chain alkyl or alkenyl, C 1 -C 4 alkoxy, C 1 -C 4 alkenyloxy, phenoxy, benzyloxy, or amino; A and A′ are each independently hydrogen, hydroxy, hydroxymethyl, C 1 -C 6 straight or branched chain alkyl, C 2 -C 6 straight or branched chain alkenyl, O—(C 1 -C 6 straight or branched chain alkyl), or O—(C 2 -C 6 straight or branched chain alkenyl), or A and A′ are taken together as ═O; L 1 is a monodentate ligand capable of acting as a ligand for said metal M, a bidentate ligand capable of acting as a ligand for said metal M, or a tridentate ligand capable of acting as a ligand for said metal M; and, L 2 is cyclopentadienylamido.