Patent ID: 8197795

Claim:
A method for monitoring protein translation in an animal having a cancerous tissue comprising: administering a cell surface receptor inhibitor of a cell surface receptor selected from the group consisting of vascular endothelial growth factor receptor (VEGFR), epidermal growth factor receptor (EGFR), fibroblast growth factor receptor (FGFR), platelet derived growth factor receptor (PDGFR), stem cell receptor (SCFR), nerve growth factor receptor (NGFR), hepatocyte growth factor (HGFR), insulin growth factor receptor (IGFR), a receptor having a tyrosine kinase domain, a receptor having a serine threonine kinase domain, a receptor utilizing a cytoplasmic tyrosine kinase, an angiogenesis factor receptor, and integrin receptor to the animal; measuring, by Magnetic Resonance Spectroscopy, the amount of Choline present in the intracellular membranes of the organelles of the cancerous tissue before and after administering the cell surface receptor inhibitor, obtaining a difference between the amounts of Choline, and correlating the difference to protein translation.