Patent ID: 8907103

Claim:
A compound of Formula I: wherein R 44 is H, CH 3 or CH 3 CH 2 ; R 45 is C 1-6 -alkyl, alkenyl, alkoxy, C 3-6 -cycloalkyl, C 4-8 -cycloalkenyl, C 4-8 -bicycloalkenyl, aryl or heteroaryl, any of which can be optionally substituted with one or more substituents selected from C 1-6 alkyl, CF 3 , F, CN or OCF 3 ; L is phenyl, indenyl, benzoxazol-2-yl, C 3-6 -cycloalkyl, C 4-8 -cycloalkenyl or C 4-8 -bicycloalkenyl, any of which can be optionally substituted with one or more substituents selected from F, Cl, CH 3 , CF 3 , OCF 3 or CN; and R 46 represents one or more substituents selected from H, F, Cl, CH 3 , CF 3 , OCF 3 or CN; or a pharmaceutically acceptable salt, solvate, or prodrug thereof having an optical purity of at least 95% of the R enantiomer.