Patent ID: 7235556

Claim:
A method for the treatment of dry eye which comprises topically administering to the eye of a mammal suffering from dry eye composition comprising a pharmaceutically acceptable carrier and a pharmaceutically effective amount of a compound formula (I) wherein: Z 1 , Z 2 independently=H, F, Br, Cl, F, or C 1-3 alkyl; Y=CH—(CH2) n or CH—O; n=0-3; A=CH or N, provided that when Y=CH—O then A=CH; A 2 =CH or N; X=(CH2) n′ Y 2 or (CH2) n -Y 3 (CH2) n′ Y 2 ; X 2 =H, OR 5 , C 1-6 alkyl, C(O)OR 6 , or C(O)N(R 7 )H; n′=2-6; n″=2-4; Y 2 =O, S, or NH Y 3 =O or S; R 1 =H, or (C(R 3 )(R 4 ))X 2 ; and R 2 , R 3 , R 4 , R 5 , R 6 , R 7 independently=H or C 1-6 alkyl.