Patent ID: 8227501

Claim:
A compound of formula I, in free or pharmaceutically acceptable salt, or enantiomeric form, wherein: R 1 is selected from the group consisting of hydrogen, linear or branched (1-6C)alkyl, and (3-6C)cycloalkyl; R 2 is selected from the group consisting of hydrogen, chlorine, bromine, phenyl, phenyl(1-2C)alkyl, COOH, and COOR 5 ; R 3 is selected from the group consisting of hydrogen, linear or branched (1-6C)alkyl, and (3-6C)cycloalkyl; R 4 is selected from the group consisting of linear or branched (1-6C)alkyl, (3-6C)cycloalkyl, CHFCH 3 , CF 3 , OH, OR 6 , NH 2 , and NHR 7 ; R 5 is selected from the group consisting of linear or branched (1-6C)alkyl, phenyl, phenyl(1-2C)alkyl, and (3-6C)cycloalkyl; R 6 is selected from the group consisting of linear or branched (1-6C)alkyl, and (3-6C)cycloalkyl; R 7 is selected from the group consisting of linear or branched (1-6C)alkyl, and (3-6C)cycloalkyl; and X is a halogen atom selected from the group consisting of fluorine, and chlorine.