Patent ID: 8445518

Claim:
A compound of the formula (I), or a salt thereof: wherein Ar is selected from the group consisting of substituted or unsubstituted C 6-10 aryl; Y 1 is —CR 3a —; Y 2 is —CR 3b —; Y 3 is —CR 3c —; Y 4 is —N—; R 3a , R 3b , and R 3c are each independently selected from the group consisting of hydrogen, halogen, —CN, —C(O)R 4 , —CO 2 R 4 , —C(O)NR 4 R 5 , —OR 4 , —OC(O)R 4 , —OC(O)NR 4 R 5 , —SR 4 , —S(O)R 4 , —S(O) 2 R 4 , —S(O) 2 NR 4 R 5 , —NO 2 , —NR 4 R 5 , —NR 4 C(O)R 5 , —NR 4 C(O)OR 5 , —NR 4 S(O) 2 R 5 , —NR 4 C(O)NR 5 R 6 , substituted or unsubstituted C 1-8 alkyl, substituted or unsubstituted C 2-8 alkenyl, substituted or unsubstituted C 2-8 alkynyl, substituted or unsubstituted 3- to 10-membered heterocyclyl, substituted or unsubstituted C 6-10 aryl, and substituted or unsubstituted 5- to 10-membered heteroaryl; R 4 , R 5 , and R 6 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C 1-8 alkyl, substituted or unsubstituted C 2-8 alkenyl, substituted or unsubstituted C 2-8 alkynyl, substituted or unsubstituted C 6-10 aryl, substituted or unsubstituted 5- to 10-membered heteroaryl, and substituted or unsubstituted 3- to 10-membered heterocyclyl; R 4 and R 5 , R 5 and R 6 or R 4 and R 6 may, together with the atoms to which they are attached, form a substituted or unsubstituted 5-, 6-, or 7-membered ring; R 1 is selected from the group consisting of hydrogen, —C(O)R 7 , —CO 2 R 7 , —C(O)NR 7 R 8 , —S(O)R 7 , —S(O) 2 R 7 , —S(O) 2 NR 7 R 8 , substituted or unsubstituted C 1-8 alkyl, C 1-8 substituted or unsubstituted cycloalkyl, substituted or unsubstituted C 2-8 alkenyl, substituted or unsubstituted C 2-8 alkynyl, and substituted or unsubstituted C 6-10 aryl; R 2 is selected from the group consisting of hydrogen, halogen, —CN, —C(O)R 7 , —CO 2 R 7 , —C(O)NR 7 R 8 , —OR 7 , —OC(O)R 7 , —OC(O)NR 7 R 8 , —SR 7 , —S(O)R 7 , —S(O) 2 R 7 , —S(O) 2 NR 7 R 8 , —NO 2 , —NR 7 R 8 , —NR 7 C(O)R 8 , —NR 7 C(O)OR 8 , —NR 7 S(O) 2 R 8 , —NR 7 C(O)NR 8 R 9 , substituted or unsubstituted C 1-8 alkyl, substituted or unsubstituted C 2-8 alkenyl, substituted or unsubstituted C 2-8 alkynyl, and substituted or unsubstituted C 6-10 aryl; and R 7 , R 8 , and R 9 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C 1-8 alkyl, substituted or unsubstituted C 2-8 alkenyl, substituted or unsubstituted C 2-8 alkynyl, and substituted or unsubstituted C 6-10 aryl.