Patent ID: 7648980

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein: Z 1 , Z 3 , and Z 4 are independently N or CR 1a ; Z 2 , Z 5 , and Z 6 are each CR 1a ; A is CR 2 R 3 ; R 1 and R 1a are independently at each occurrence hydrogen; cyano; halo; hydroxy; (C 1-6 )alkoxy; R 2 is hydrogen; halo; hydroxy; or (C 1-6 )alkoxy; R 3 is hydrogen; R 8 is hydrogen; halo; hydroxyl; or (C 1-6 )alkyl; R 11 is hydrogen, (C 1-6 )alkyl, (C 1-6 )alkoxycarbonyl, or (C 1-6 )alkylcarbonyl; R 12 is UR 13 ; U is CH 2 ; C(═O); or SO 2 ; R 13 is a substituted or unsubstituted heterocyclic ring system (A): X is O or S R 15 is at each occurrence independently hydrogen; (C 1-4 )alkyl; (C 1-4 )alkoxy; halo or trifluoromethyl.