Patent ID: 7951950

Claim:
A compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof, wherein: Ring A is an optionally substituted, fused 5-6 membered aryl or heteroaryl ring; Y is >C(R x )—; X 1 is —C(═O)—, —SO 2 —, —CONR—, —C(R) 2 —, or —CO 2 —, R 1 is an optionally substituted group selected from a monocyclic or bicyclic aryl, a monocyclic or bicyclic heteroaryl, a monocyclic or bicyclic non-aromatic heterocyclic, or a monocyclic or bicyclic non-aromatic carbocylic group; R 2 is a C 1 -C 3 alkyl group, a C 1 -C 3 haloalkyl group or C 3 -C 6 cycloalkyl group wherein the C 1 -C 3 alkyl group represented by R 2 is optionally substituted with R 5 ; R 3 is hydrogen, C 1 -C 6 alkyl optionally substituted by R 6 , C 1 -C 6 fluoroalkyl, or an optionally substituted group selected from a C 3 -C 8 cycloalkyl, a monocyclic non-aromatic heterocyclic, a monocyclic aryl, or a monocyclic heteroaryl group; R 4 is —[C(R 7 ) 2 ] m —B; or R 3 and R 4 may be taken together with the intervening nitrogen atom to form an optionally substituted monocyclic or bicyclic heteroaryl or non-aromatic heterocyclic group; or R x and R 4 may be taken together with the intervening carbon and nitrogen atoms to form an optionally substituted monocyclic non-aromatic nitrogen-containing heterocyclic group; R 5 is —OH, —O(C 1-4 aliphatic), —COOR′ or —N(R′) 2 ; R 6 is —OH, —O(C 1-4 aliphatic), —N(R′) 2 , —C(O)R′, —COOR′, C(O)N(R′) 2 , or an optionally substituted group selected from a monocyclic cycloalkyl, a monocyclic aryl, a monocyclic heteroaryl, or a monocyclic non-aromatic heterocyclic group; each R 7 is independently hydrogen, fluoro, or C 1 -C 3 alkyl; each R, R x or R′ is independently hydrogen or a C 1 -C 4 aliphatic group or N(R′) 2 is a monocyclic non-aromatic nitrogen-containing heterocyclic group; m is zero or one; and B is —H, —C(R 7 ) 3 , —C(R 7 ) 2 —C(R 7 ) 3 , or an optionally substituted group selected from a monocyclic or bicyclic cycloalkyl, a monocyclic or bicyclic aryl, a monocyclic or bicyclic heteroaryl, or a monocyclic or bicyclic non-aromatic heterocyclic group.