Patent ID: 8211937

Claim:
A compound of formula (I): wherein: A represents an aromatic 5 membered heterocycle, optionally containing, in addition to the nitrogen atom indicated in formula (I), one to three additional nitrogen atoms and optionally substituted by one or more groups; R is selected from halogen, —NRaRb, C 1-6 alkyl, C 2-6 alkenyl, C 3-6 alkynyl, aryl, heteroaryl, hydroxy, —OC 1-6 alkyl, formyl, cyano, trifluoromethyl, —CHNORa, —CO 2 Ra, —CONRaRb, —NRaC(O)Ra, —NRaC(O)ORa, —OC(O)NRaRb, —OC(O)Ra, —OC(O)ORa, and a C 1-6 alkyl group substituted by one or more groups selected from hydroxy, —NRaRb, —OC 1-6 alkyl, —SRa, —CHNORa, —CO 2 Ra, —CONRaRb, —NRaC(O)Ra, —NRaC(O)ORa, —OC(O)NRaRb, —OC(O)Ra, and —OC(O)ORa; X represents —NRxRy or —OC 1-6 alkyl optionally substituted by one or more groups selected from hydroxy, methoxy, halogen, amino and trifluoromethyl; Ra and Rb independently represent hydrogen or C 1-6 alkyl; R 1 represents hydrogen, or C 1-6 alkyl; R 2 represents hydroxy; R 3 represents methyl; R 4 represents hydrogen, or C 1-6 alkyl, optionally substituted by one or more groups selected from hydroxy, methoxy, halogen, amino and trifluoromethyl; Rx and Ry independently represent hydrogen, benzyl, C 3-6 cycloalkyl, C 3-6 alkenyl, C 3-6 alkynyl, C 1-6 alkyl optionally substituted by one or more groups selected from hydroxy, methoxy, halogen, NRaRb and trifluoromethyl, —C 1-6 alkylcycloalkyl, —C 1-6 alkylheterocycle, C 1-6 alkylamino and C 1-6 alkylthio or together Rx and Ry form a heterocycle; or a pharmaceutically acceptable salt thereof.