Patent ID: 8007794

Claim:
An isolated antibody comprising a. CDR H1 as set forth in SEQ ID NO: 3: b. CDR H2 as set forth in SEQ ID NO: 4, or variants as shown in Table 6; c. CDR H3 as set forth in SEQ ID NO: 5: d. CDR L1 as set forth in SEQ ID NO: 6, or variants as shown in Table 6; e. CDR L2 as set forth in SEQ ID NO: 7, or variants as shown in Table 6; and f. CDR L3 as set forth in SEQ ID NO: 8; wherein the antibody has a binding affinity (K D ) to human α-CGRP of 50 nM or less as measured by surface plasmon resonance at 37° C.