Patent ID: 8546401

Claim:
A compound of the formula I.A in which R 1 and R 2 are independently of one another hydrogen, C 1 -C 3 -alkyl, C 1 -C 3 -fluoroalkyl, C 1 -C 3 -alkoxy, C 1 -C 3 -fluoroalkoxy, halogen or CN; R 3 is hydrogen or C 1 -C 4 -alkyl; R 4 is ethoxy, fluorinated ethoxy or isopropoxy; R 5 is hydrogen or methyl; R 6 is Br, Cl, F or CN; R 7 is Cl, F or CN; X 1 is O, NH or CH 2 ; X 2 and X 3 are N or CH, with the proviso that X 2 and X 3 are not simultaneously N; and X 4 is N or CH; and their pharmaceutically acceptable salts and prodrugs thereof.