Patent ID: 7273861

Claim:
A compound represented by formula 1: wherein R 1 is selected from the group consisting of H, halogen, (C 1-4 )alkyl, O(C 1-4 )alkyl, and haloalkyl; R 2 is H or Me; R 3 is H or (C 1-4 )alkyl; R 4 is H or (C 1-4 )alkyl; R 5 is (C 1-4 )alkyl, (C 1-4 )alkyl(C 3-7 )cycloalkyl, or (C 3-7 )cycloalkyl; and W is selected from: wherein, a) one of Y is SO 2 and the other Y is NR 6 , provided that both are not the same, wherein R 6 is selected from the group consisting of: H, C(O)O(C 1-4 alkyl, (C 1-4 )alkyl or (C 1-4 ) alkyl substituted with either a pyridinyl-N-oxide or C(O)OR 8 wherein R 8 is H or (C 1-4 ) alkyl; and each R 9 is independently H or (C 1-4 ) alkyl; and b) E is CR 10 R 10 wherein each R 10 is independently H or (C 1-4 ) alkyl, J is CH 2 and the dotted line represents a single bond; or c) E and J are both CR 11 wherein R 11 is H or (C 1-4 ) alkyl and the dotted line represents a double bond; or W is selected from: wherein, m is 1 or 2, R 12 is H or C (1-4) alkyl, R 13 is H or (C 1-4 ) alkyl, and Z is O or Z is NR 14 wherein R 14 is H or (C 1-4 ) alkyl; or W is selected from a group of aromatic radicals consisting of: wherein R 15 is (C 1-4 ) alkyl or CF 3 , and n is the integer 0, 1 or 2, or a pharmaceutically acceptable salt or ester thereof.