Patent ID: 8551995

Claim:
A compound of formula II: or a salt thereof; wherein: R 1 is arylalkyl or heteroarylalkyl, each optionally substituted with 1-4 independent Z 1 ; R 2 is C 6 -C 14 aryl, 5-12 membered heteroaryl, 3-15 membered heterocyclyl or amide, each optionally substituted with 1-4 independent Z 2 ; R 3 is hydrogen, hydroxyl, alkoxy, or alkylamino; R 5 is NH 2 ; Each Z 1 and Z 2 is independently halogen, CN, NO 2 , OR 15 , SR 15 , S(O) 2 OR 15 , NR 15 R 16 , C 1 -C 2 perfluoroalkyl, C 1 -C 2 perfluoroalkoxy, 1,2-methylenedioxy, C(O)OR 15 , C(O)NR 15 R 16 , OC(O)NR 15 R 16 , NR 15 C(O)NR 15 R 16 , C(NR 16 )NR 15 R 16 , NR 15 C(NR 16 )NR 15 R 16 , S(O) 2 NR 15 R 16 , R 17 , C(O)R 17 , NR 15 C(O)R 17 , S(O)R 17 , S(O) 2 R 17 , R 16 , oxo, C(O)R 16 , C(O)(CH 2 )nOH, (CH 2 )nOR 15 , (CH 2 )nC(O)NR 15 R 16 , NR 15 S(O) 2 R 17 , where n is independently 0-6 inclusive; Each R 15 is independently hydrogen, C 1 -C 4 alkyl or C 3 -C 6 cycloalkyl; Each R 16 is independently hydrogen, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 6 cycloalkyl, C 6 -C 14 aryl, 3-15 membered heterocyclyl, 5-12 membered heteroaryl, C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted with C 3 -C 6 cycloalkyl, C 6 -C 14 aryl, 3-15 membered heterocyclyl or 5-12 membered heteroaryl; and Each R 17 is independently C 3 -C 6 cycloalkyl, C 6 -C 14 aryl, 3-15 membered heterocyclyl, 5-12 membered heteroaryl, C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted with C 3 -C 6 cycloalkyl, C 6 -C 14 aryl, 3-15 membered heterocyclyl or 5-12 membered heteroaryl.