Patent ID: 7377907

Claim:
A fluid drug delivery device comprising: (a) a cartridge including a fluid supply assembly, a fluid outlet, and a flow control arrangement including a flow control valve, said flow control arrangement controlling flow from said fluid supply assembly to said fluid outlet, said flow control valve being operated by displacement of at least one actuation surface provided by said cartridge, said actuation surface being isolated from contact with the fluid; (b) a portable base unit configured for receiving said cartridge in removable engagement with said base unit, said base unit including: (i) a processing unit, and (ii) a piezoelectric actuator controlled by said processing unit; and (c) an adjustment mechanism associated with one of said cartridge and said base unit, said adjustment mechanism being operative, after engagement of said cartridge with said base, to bring said piezoelectric actuator into mechanical engagement with said actuation surface with substantially a predefined initial contact pressure.