Patent ID: 8129375

Claim:
A compound of Formula I: or a pharmaceutically acceptable salt, prodrug, or stereoisomer thereof, wherein: X is C(═O) or CH 2 ; Y is O, cyanamido (N—≡N), or amido (NH); m is an integer of 0, 1, 2, or 3; R 1 is hydrogen or C 1-6 alkyl; R 2 is hydrogen, —NO 2 , C 1-10 alkyl, C 0-6 alkyl-(5 to 10 membered heteroaryl), C 0-6 alkyl-(5 to 6 membered heterocyclyl), C 0-6 alkyl-OH, C 0-4 alkyl-NH 2 , —NHCO—C 1-6 alkyl, —OR 21 , or —(CH 2 -Z) 0-2 -(5 to 10 membered heteroaryl), where each heteroaryl and heterocyclyl is optionally substituted with one or more C 1-6 alkyl; R 3 is hydrogen, halogen, —NO 2 , C 0-6 alkyl-(5 to 10 membered heteroaryl), C 0-6 alkyl-(5 to 6 membered heterocyclyl), C 0-6 alkyl-OH, C 0-4 alkyl-NH 2 , —NHCO—C 1-6 alkyl, —OR 21 , or —(CH 2 -Z) 0-2 -(5 to 10 membered heteroaryl), where each heteroaryl and heterocyclyl is optionally substituted with one or more C 1-6 alkyl; R 21 is C 6-10 aryl, 5 to 10 membered heteroaryl, 5 to 6 membered heterocyclyl, or —CO(CH 2 ) 0-2 R 22 , wherein the aryl, heteroaryl, and heterocyclyl are each optionally substituted with one or more C 1-6 alkyl; R 22 is —NH 2 or 5 to 6 membered heterocyclyl; and Z is CH 2 , NH, or O; with the proviso that when R 1 is hydrogen, then R 2 is not hydrogen or C 1-10 alkyl; with the proviso that when Y is O, then R 3 is not halogen; and with the proviso that when Y is O and R 3 is halogen, then R 2 is C 0-6 alkyl-(5-6 membered heterocyclyl).