Patent ID: 8541552

Claim:
An isolated anti-lymphotoxin-α (LTα) antibody comprising a light chain variable region wherein the complementarity-determining region (CDR)-L1 sequence is KSSQSLLYSTXQKXFLA (SEQ ID NO:3) or KSSQSLLYSAXQKXFLA (SEQ ID NO:4) or KSSQSLLYSTXQKXALA (SEQ ID NO:6), where X is any amino acid; the CDR-L2 sequence is WASTRDS (SEQ ID NO:8); the CDR-L3 sequence is QQYYSYPRT (SEQ ID NO:13) or QQYASYPRT (SEQ ID NO:14) or QQYYAYPRT (SEQ ID NO:15), and a heavy chain variable region wherein the CDR-H1 sequence is GYTFSSYWIE (SEQ ID NO:17); the CDR-H2 sequence is EISPGSGSTXYXEEFKG (SEQ ID NO:19) or EIXPGSGSTIYXEKFKG (SEQ ID NO:110), wherein X is any amino acid; and the CDR-H3 sequence is GYHGY (SEQ ID NO:21) or GYHGA (SEQ ID NO:22).