Patent ID: 7632847

Claim:
A compound of formula Ib: wherein: a is 0 or 1; R 1 is halo; b is 0 or 1; R 2 is halo; m is 0 or 1; Z 1′ is —C(O)N(R 4 )— and Z 2′ is selected from —C(O)N(R 6 )— and —N(R 6 )C(O)—; or Z 1′ is —N(R 4 )C(O)— and Z 2′ is —N(R 6 )C(O)—; R 4 is selected from hydrogen and (1-4C)alkyl; R 6 is selected from hydrogen and (1-4C)alkyl; n is 0 or 1; Ar 1 represents a phenylene group substituted with (R 5 ) p where p is 0 or an integer from 1 to 4 and each R 5 is independently selected from halo, hydroxy, (1-4C)alkyl, and (1-4C)alkoxy; q is 0 or 1; r is 0, 1 or 2; R 7 is selected from hydrogen and (1-4C)alkyl; X 1 is (1-3C)alkylene optionally substituted with 1 or 2 substituents independently selected from (1-4C)alkyl and —NR Xa R Xb ; wherein R Xa and R Xb are independently selected from hydrogen and (1-4C)alkyl; s is 0 or 1; R 8 is —OR 8a ; and R 8a is hydrogen, (1-4C)alkyl, (3-6C)cycloalkyl, phenyl, or phenyl(1-4C)alkyl, wherein each phenyl group is unsubstituted or substituted by 1 or 2 substituents independently selected from halo, (1-4C)alkyl, and (1-4C)alkoxy; R 9 is selected from hydrogen, (1-4C)alkyl, (1-4C)alkyleneNR 9a R 9b , and phenyl, each of R 9a and R 9b is independently hydrogen or (1-4C)alkyl; and wherein each alkyl and alkoxy group in R 5 , R 8a , R 9 , and R 9a-9b is optionally substituted with 1 to 5 fluoro substituents; or a pharmaceutically acceptable salt or stereoisomer thereof.