Patent ID: 8106064

Claim:
A compound of Formula (I) or (II): or a pharmaceutically acceptable salt thereof, wherein: X and Y are independently O; A is —O—, —S—, NR 5 or —C(R 6 ) 2 —; D is alkylene or substituted alkylene; L is a covalent bond, alkylene, substituted alkylene, alkenylene, or substituted alkenylene; R 1 is pyridyl or substituted pyridyl; R 2 is H, halogen, nitro, alkyl, substituted alkyl, alkoxyalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, amino, alkylamino, dialkylamino, cycloalkyl, or substituted cycloalkyl; R 3 is phenyl; R 4 is H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, arylalkyl, or substituted arylalkyl; R 8 is H, —C(O)—O-alkyl, —C(O)—O-(substituted alkyl), —C(O)-alkyl-, or C(O)-(substituted alkyl); R 5 is H, alkyl, substituted alkyl, arylalkyl, substituted arylalkyl, acyl, or substituted acyl; each R 6 is independently H, alkyl, hydroxy, alkoxy, cyano, or halo; or each R 6 , together with the carbon atom to which they are shown attached, form a —C(O)—, —C(S)—, —C(NR 7 )—, or cycloalkyl; R 7 is H, alkyl, substituted alkyl, hydroxy, or alkoxy; each W and Z is independently selected from the group consisting of halo, nitro, hydroxy, amino, substituted amino, -amino-C(O)-alkylene-amino, sulfonamido, acetamido, trifluoroacetamido, azido, cyano, formyl, carbamoyl, alkyl, substituted alkyl, alkylcarbamoyl, dialkylcarbamoyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, alkoxycarbonyl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, or oxide; and n and m are independently integers of from 0 to 4; wherein a substituent of each substituted alkylene, substituted alkenylene, substituted alkyl, substituted alkenyl, substituted alkynyl, substituted cycloalkyl, substituted arylalkyl, substituted acyl, substituted heterocyclyl, substituted amino, substituted alkoxy, substituted cycloalkenyl, or substituted aryl is independently selected from the group consisting of —X, —R, —O—, ═O, —OR, —SR, —S—, —NR 2 , —N + R 3 , —CX 3 , —CN, —OCN, —SCN, —NCS, —NO, —NO 2 , ═N 2 , —N 3 , —NHC(═O)R, —C(═O)R, —C(═O)NRR, —S(═O) 2 O—, —S(═O) 2 OH, —S(═O) 2 R, —OS(═O) 2 OR, —S(═O) 2 NR, —S(═O)R, —OP(═O)(OR) 2 , —N(═O)(OR) 2 , —N(═O)(O—) 2 , —N(═O)(OH) 2 , —N(O)(OR)(O—), —C(═O)R, —C(═O)X, —C(S)R, —C(O)OR, —C(O)O—, —C(S)OR, —C(O)SR, —C(S)SR, —C(O)NRR, —C(S)NRR, and —C(═NR)NRR; X is —F, —Cl, —Br, or —I; and each R is independently H, alkyl, aryl, arylalkyl, or heterocyclyl.