Patent ID: 8299086

Claim:
A compound of the formula (I) wherein A represents wherein the asterisks indicate the bond that is linked to the pyrimidine group of formula (I); R 1 represents C 1-4 -alkoxy, C 1-4 -alkylamino, N—C 1-4 -alkyl-N—C 1-3 -alkylamino, C 3-5 -cycloalkylamino, C 3-5 -cycloalkylmethylamino, pyrrolidine, or piperidine; R 2 represents C 1-2 -alkyl or C 3-4 -alkyl; R 3 represents hydrogen, C 1-4 -alkyl, or C 1-3 -alkoxy; R 4 represents hydrogen, C 1-4 -alkyl, or C 1-3 -alkoxy; R 5 represents 2,3-dihydroxypropyl, di-(hydroxy-C 1-4 -alkyl)-C 1-4 -alkyl, —CH 2 —(CH 2 ) k —NHSO 2 R 53 , —(CH 2 ) n CH(OH)—CH 2 —NHSO 2 R 53 , —CH 2 —(CH 2 ) k —NHCOR 54 , —(CH 2 ) n CH(OH)—CH 2 —NHCOR 54 , —CH 2 —(CH 2 ) n —CONR 51 R 52 , 1-(3-carboxy-azetidinyl)-2-acetyl, 1-(2-carboxy-pyrrolidinyl)-2-acetyl, 1-(3-carboxy-pyrrolidinyl)-2-acetyl, 1-(3-carboxy-azetidinyl)-3-propionyl, 1-(2-carboxy-pyrrolidinyl)-3-propionyl, 1-(3-carboxy-pyrrolidinyl)-3-propionyl, —(CH 2 ) n CH(OH)—CH 2 —NR 51 R 52 , hydroxy-C 2-5 -alkoxy, di-(hydroxy-C 1-4 -alkyl)-C 1-4 -alkoxy, 2,3-dihydroxy-propoxy, 2-hydroxy-3-methoxy-propoxy, —OCH 2 —(CH 2 ) m —NR 51 R 52 , 2-[(azetidine-3-carboxylic acid)-1-yl]-ethoxy, 2-[(azetidine-3-carboxylic acid C 1-5 -alkylester)-1-yl]-ethoxy, 2-[(pyrrolidine-3-carboxylic acid)-1-yl]-ethoxy, 2-[(pyrrolidine-3-carboxylic acid C 1-5 -alkylester)-1-yl]ethoxy, —OCH 2 —CH(OH)—CH 2 —NR 51 R 52 , 3-[(azetidine-3-carboxylic acid)-1-yl]-2-hydroxypropoxy, 3-[(azetidine-3-carboxylic acid C 1-5 -alkylester)-1-yl]-2-hydroxypropoxy, 2-hydroxy-3-[(pyrrolidine-3-carboxylic acid)-1-yl]-propoxy, 2-hydroxy-3-[(pyrrolidine-3-carboxylic acid C 1-5 -alkylester)-1-yl]-propoxy, 2-hydroxy-3-[(pyrrolidine-2-carboxylic acid)-1-yl]-propoxy, 2-hydroxy-3-[(pyrrolidine-2-carboxylic acid C 1-5 -alkylester)-1-yl]-propoxy, —OCH 2 —(CH 2 ) m —NHSO 2 R 53 , —OCH 2 —CH(OH)—CH 2 —NHSO 2 R 53 , —OCH 2 —(CH 2 ) m —NHCOR 54 , or —OCH 2 —CH(OH)—CH 2 —NHCOR 54 ; R 51 represents hydrogen, C 1-3 -alkyl, 2-hydroxyethyl, 2-hydroxy-1-hydroxymethyl-ethyl, 2,3-dihydroxypropyl, carboxymethyl, (C 1-5 -alkylcarboxy)methyl, 2-carboxyethyl, 2-(C 1-5 -alkylcarboxy)ethyl, or 2-aminoethyl; R 52 represents hydrogen, methyl, or ethyl; R 53 represents C 1-3 -alkyl, methylamino, ethylamino, or dimethylamino; R 54 represents hydroxy-C 1-2 -alkyl or R 55 R 56 N—C 1-2 -alkyl; R 55 and R 56 independently represent hydrogen or methyl; k represents the integer 1, 2, or 3; m represents the integer 1 or 2; n represents 0, 1, or 2; and R 6 represents hydrogen, C 1-4 -alkyl, or halogen; or a salt of such a compound.