Patent ID: 6897226

Claim:
A compound of the formula: wherein R is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; R 1 is hydrogen or halogen; or R and R 1 when adjacent, together with the ring carbon atoms to which they are attached are —CH═CH—CH═CH—; R 2 and R 2′ are hydrogen, halogen, trifluoromethyl, lower alkoxy or cyano; or R 2 and R 2′ when adjacent, together with the ring carbons to which they are attached are —CH═CH—CH═CH—, unsubstituted or substituted by one or two substituents selected from lower alkyl or lower alkoxy; R 3 and R 3′ are hydrogen, lower alkyl or cycloalkyl; R 4 and R 4′ together with the N-atom to which they are attached form a 5 member nitrogen containing heterocyclic ring of the structure: said heterocyclic ring having 0 or 1 additional hetero-atoms selected from sulfur, nitrogen and oxygen, said additional hetero-sulfur atom being a sulfonyl moiety; R 5 is hydrogen, hydroxy, lower alkyl, -lower alkoxy, —(CH 2 ) m OH, —COOR 3 , —CON(R 3 ) 2 , —N(R 3 )CO-lower alkyl or —C(O)R 3 ; R 6 is lower alkyl; X is —C(O)N(R 6 )——N(R 6 )C(O)—, (CH 2 ) m O—, —O(CH 2 ) m —; n is 0, 1, 2, 3 or 4; and m is 1, 2 or 3, or a pharmaceutically acceptable acid addition salt thereof.