Patent ID: 7271185

Claim:
A method for producing an optically active azole-methyl alcohol derivative represented by general formula (5): (wherein R1 represents a substituted or unsubstituted alkyl group; R2 represents an ether protective group, an acetal protective group, or a silyl protective group, which is a protective group for a hydroxyl group; each of R5 and R6 independently represents a halogen atom; symbol * represents an asymmetric carbon having an R configuration or an S configuration; and Y represents a carbon atom or a nitrogen atom) the method comprising: allowing an optically active azole-methyl ketone derivative represented by general formula (3): (wherein R1, R2, Y, and symbol * are as defined above) to diastereoselectively react with a phenyl metallic reagent represented by general formula (4): (wherein R5 and R6 are as defined above; A represents Li, MgX, ZnX, TiX 3 , Ti(OR7) 3 , CuX, or CuLi, {wherein X represents a halogen atom, and R7 represents a substituted or unsubstituted alkyl group}).