Patent ID: 8686028

Claim:
Substituted benzfurochromenes having the general formula I, and salts and chiral or achiral compounds thereof; wherein R 1 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently selected from the groups consisting of hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkoxyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkylthio, optionally substituted amino, optionally substituted acylamino, optionally substituted arylamino, optionally substituted acylthio, optionally substituted acyl, optionally substituted aroyl, optionally substituted acyloxy, optionally substituted thioamido, halogens, nitriles, esters, hydroxy, mercapto, carbontrifluoride and nitro; R 2 is independently selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkoxyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkylthio, optionally substituted amino, optionally substituted acylamino, optionally substituted arylamino, optionally substituted acylthio, optionally substituted acyl, optionally substituted aroyl, optionally substituted acyloxy, optionally substituted thioamido, halogens, nitriles esters, mercapto, carbontrifluoride, and nitro; wherein R 1 R 2 or R 2 R 3 or R 6 R 7 may be connected and form either a five membered ring or a six membered ring selected from the group consisting of substituted furan, unsubstituted furan, substituted dihydrofuran, unsubstituted dihydrofuran, substituted pyran and unsubstituted pyran, or may be connected through a methylenedioxy moiety; wherein X is selected from the units consisting of a ketone group, optionally substituted methylene group, and optionally substituted alkene; and wherein Y and Z is selected from the units consisting of CH, Câ€”OH, C-Me, and Câ€”OMe with the proviso that bond between Y and Z is a single bond.