Patent ID: 8391962

Claim:
A method of stratifying risks of an adverse cardiac event comprising the steps of: ascertaining, from a first duration of electrocardiographic records, RR and QT interval data; determining mean RR and QT interval data, denoted by RR MEAN and QT MEAN , respectively; fitting, with a calculator, at least a portion of at least one of the RR and QT interval data to at least one of first and second formulas that include fitting related measures and define RR FIT and QT FIT , respectively, said first formula being, RR fit =RR mean +Cr cos [(2π/24)( t+φ R )], and said second formula being, QT fit =QT mean +Cq cos [(2π/24)( t+φ Q )], wherein t represents a temporal measure and said fitting at least partially establishes the fitting related measures Cr, Cq, φ R , and φ Q , said Cr and Cq denoting RR and QT circadian amplitude coefficients, respectively, and said φ R and φ Q denoting RR and QT acrophases, respectively; establishing at least a first correlation between at least a first cardiac adversity relative risk related attribute and at least one of the fitting related measures; and stratifying relative risk of at least a first cardiac adversity in response to the at least a first correlation, said stratifying involving at least a first stratifying mathematical expression, said first stratifying mathematical expression involving at least two of the fitting related measures.