Patent ID: 8372990

Claim:
A substituted bicyclic tetrahydropyrrole compound of general formula (I) wherein R 1 represents a benzyl group in which the methylene moiety of the benzyl group and the aromatic moiety of the benzyl group are independently unsubstituted or substituted by one or more substituents independently selected from the group consisting of a C 1-4 alkyl group, a linear or branched C 1-6 alkoxy group, F, CI, I, Br, CF 3 , CH 2 F, CHF 2 , CN, OH, SH, NH 2 , (C═O)R′, SR′, SOR′, SO 2 R′, NHR′, and NR′R″, wherein R′ and R″ for each substituent independently represents a linear or branched C 1-6 -alkyl group, and wherein the aromatic moiety is condensed with or is not condensed with a substituted or unsubstituted mono- or polycyclic ring system; or a benzhydryl group which is unsubstituted or substituted by one or more substituents independently selected from the group consisting of a C 1-4 alkyl group, a linear or branched C 1-6 alkoxy group, F, CI, I, Br, CF 3 , CH 2 F, CHF 2 , CN, OH and SH; wherein the bond between Y and Z is saturated (Y—Z), with Y representing C—R 11 R 12 ; and Z representing CH—R 6 ; or wherein the bond between Y and Z is unsaturated (Y═Z), with Y representing CH and Z representing a C—R 6 group; R 6 represents an unbranched or branched C 1-6 alkyl group which is unsubstituted or substituted by one or more substituents independently selected from the group consisting of a F, CI, I, Br, CF 3 , CH 2 F, CHF 2 , CN, OH, SH, and NH 2 ; a phenyl group which is unsubstituted or substituted by one or more substituents independently selected from the group consisting of a C 1-4 alkyl group, an unsubstituted or substituted phenyl group, a linear or branched C 1-6 alkoxy group, F, CI, I, Br, CF 3 , CH 2 F, CHF 2 , CN, OH, SH, NH 2 , (C═O)R′, SR′, SOR′, SO 2 R′, N(C═O)—OR′, NHR′, and NR′R″, wherein R′ and R″ for each substituent independently represents a linear or branched C 1-6 -alkyl group; or a trimethylsilyl group; R 11 represents a hydrogen; and R 12 represents a linear or branched, saturated or unsaturated, substituted or unsubstituted C 1-6 aliphatic group; or a substituted or unsubstituted phenyl group; or wherein the bond between Y and Z is saturated (Y—Z), with Y representing CH 2 ; and Z representing CH—R 6 ; R 6 represents a phenyl group which is unsubstituted or substituted by one or more substituents independently selected from the group consisting of a C 1-4 alkyl group, an unsubstituted or substituted phenyl group, a linear or branched C 1-6 alkoxy group, F, Cl, I, Br, CF 3 , CH 2 F, CHF 2 , CN, OH, SH, NH 2 , (C═O)R′, SR′, SOR′, SO 2 R′, N(C═O)—OR′, NHR′, and NR′R″, wherein R′ and R″ for each substituent independently represents a linear or branched C 1-6 -alkyl group; or a trimethylsilyl group; optionally in a form of one of the stereoisomers, enantiomers, or diastereomers, a racemate, or a mixture of at least two of the stereoisomers, or a corresponding salt thereof.