Patent ID: 8487139

Claim:
A curcumin dimer having the formula II: Z a -L a -Y a -(L b ) n3 -Y b -L c -Z b (II) wherein: Z a and Z b are represented by A is independently —CH 2 —CH 2 —or —CH═CH—; L a , L b , and L c are independently —[C(O)] n1 —R 1a —; n1 is independently 0 or 1; R 1a is independently R 2 , R 4 or R 5 ; R 2 is independently a saturated or unsaturated, branched or unbranched hydrocarbyl with 1 to 18 carbon atoms; R 3a is —(CH 2 —CH 2 —O) n2 —; R 3b is —(O—CH 2 —CH 2 ) n2 —; n2 is independently an integer between 1 and 2,000; R is —R 2 —R 3b —or —R 3a —R 2 —; R 5 is —R 9 —R 6 —R 9 —; R 6 is —C(O)—NH—R 3a —; Y a and Y b are independently —COOR 9 —, -triazolyl-, —NH—, —O—, or —S—S—; R 9 is C 1-4 alkyl; n3 is independently 0 or 1; when n3 is 1, L b has at least one covalent bond between L b and both Y a and Y b .