Patent ID: 8221452

Claim:
An assembly for introducing a closure material to seal a vessel puncture site adjacent a vessel, the closure material comprising a mixture of a first and second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue puncture and having a distal end, at least one fluid delivery port adjacent the catheter distal end to occupy a position adjacent the vessel puncture site, and a lumen in the catheter in fluid communication with the fluid delivery port, one or more dispensers in fluid communication with the catheter lumen for dispensing the first and second fluid compositions in the catheter lumen, a static mixer incorporated in the catheter lumen for mixing the first and second fluid compositions, an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers into the catheter lumen and mixed by flowing the first and second fluid compositions through the static mixer incorporated in the catheter and dispensed from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site, wherein the catheter is sized to block flow of the fluid mixture from the fluid delivery port into a substantial part of the tissue puncture, whereby a localized in situ closure forms adjacent the vessel puncture site to seal the vessel puncture site, and at least one position sensing mechanism adjacent the distal end for indicating whether the position sensing mechanism is located within or outside of the vessel adjacent the vessel puncture site.