Patent ID: 7786297

Claim:
An isolated, micronized form of 5-(4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile Form I having a median particle size less than about 20 μm prepared by micronizing purified Form I of 5-(4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile having: (i) a differential scanning calorimetry thermogram having an endotherm with a T onset at about 230° C.; (ii) an X-ray diffraction peak pattern comprising peaks at 2θ of about 6.6°, 10.3°, 14.4°, 19.8°, 23.8°, 26.3°, and 29.1°; and (iii) a melting point of 229 to 231° C.