Patent ID: 7087589

Claim:
A compound of the formula wherein R 1 is hydrogen, alkyl, cycloalkyl, alkoxy, cycloalkoxy, aryl, arylalkyl, acyl, arylsulfonyl, thiazolyl or bicycloalkyl, each of which, other than hydrogen, may be further substituted with a member selected from the group consisting of hydroxyl, dihydrogen phosphato, halo, amino, cyano, alkaxy, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, arylalkyl, acyl, sulfonamido, carboxyl, and carboxamido; R 2 is hydrogen, halo, alkyl, aryl, arylamino, aryloxy, alkynyl, alkenyl, mercapto, cyano, alkylthio, or arylalkylthio; R 4 and R 5 are each independently hydrogen, hydroxyl, alkoxy, alkyl, alkenyl, alkynyl, aryl, acyl, alkylamino, arylamino, dihydrogen phosphato, trihydrogen diphosphato, tetrahydrogen triphosphato, dihydrogen imidodiphosphato, trihydrogen imidotriphosphato, dihydrogen methylenediphosphato, or dihydrogen halomethylene diphosphato, and can be the same or different; R 3 is hydroxyl, alkoxy, alkyl, alkenyl, alkynyl, aryl, acyl, alkylamino, arylamino, dihydrogen phosphato, dihydrogen imidodiphosphato, dihydrogen methylenediphosphato, or dihydrogen halomethylene diphosphato; R 6 is hydrogen, alkyl, alkenyl, alkynyl, heteroaryl or aminoalkyl; R 7 is methylene, dihalomethylene, carbonyl, or sulfoxide; and at least one of R 1 , R 2 , and R 6 is other than hydrogen; and R 8 is nitrogen; wherein said alkyl is a C 1 –C 20 alkyl; said alkenyl is a C 2 –C 20 alkenyl; said alkynyl is a C 2 –C 20 alkynyl; and said aryl has no more than 8 carbon atoms in an aromatic ring; wherein any of R 2 –R 7 other than hydrogen may be further substituted with one or more substituents selected from the group consisting of amino, cyano, alkoxyl, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, arylalkyl, acyl, halo, hydroxyl, dihydrogen phosphato, sulfonamido, carboxyl, mercapto, and carboxamido, or a salt of said compound.