Patent ID: 8906351

Claim:
A method for lightening the skin; for inhibiting tyrosinase; or for the therapy of a tyrosinase-promoted disorder of the skin, comprising administering to a subject in need thereof an effective amount of a compound of formula (I) in which R1 denotes A, Cyc, F, —(CY 2 ) p —OY, —(CY 2 ) p —NYY, —(CY 2 ) p —COOY, —(CY 2 ) p —CO—NYY, —(CY 2 ) p —NY—COY or Ar, R2 denotes H, A, Cyc, F, —(CY 2 ) p —OY, —(CY 2 ) p —NYY, —(CY 2 ) p —COOY, —(CY 2 ) p —CO—NYY, —(CY 2 ) p —NY—COY or Ar, Y denotes H or Alk, A denotes unbranched or branched alkyl having 1-18 C atoms, where, independently of one another, 1-3 H atoms are optionally replaced by F and/or, independently of one another, one or two adjacent CH 2 groups are optionally replaced by —O—, —N(Alk)-, a —CH═CH— and/or —C≡C— group, Alk denotes unbranched or branched alkyl having 1-12 C atoms, Cyc denotes cyclic alkyl having 3-10 C atoms, where, independently of one another, 1-3 H atoms are optionally replaced by F and/or, independently of one another, one or two adjacent CH 2 groups are optionally replaced by —O—, —N(Alk)-, a —CH═CH— and/or —C≡C— group, Ar denotes a mono-, bi- or tricyclic aromatic carbocycle having 3 to 20 C atoms, which is unsubstituted or mono-, di- or trisubstituted by F, A, —(CY 2 ) p —OY, —(CY 2 ) p —NYY, —(CY 2 ) p —COOY, —(CY 2 ) p —CO—NYY or —(CY 2 ) p —NY—COY, and m, n, p, independently of one another, denote 0, 1, 2 or 3, or a pharmaceutically acceptable salt, tautomer, stereoisomer or solvate thereof.