Patent ID: 8470820

Claim:
A compound of formula (I) wherein A 1 and A 2 are each independently selected from the group consisting of CH and N, provided that A 1 and A 2 are not simultaneously N; R 1 is lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, lower alkyl-C(O)—, cyano, halogen, amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl, cycloalkyl, or heterocyclyl; R 2 and R 3 are each independently hydrogen or lower alkyl; R 4 is heteroaryl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl; Y is 5-membered heteroaryl selected from the group consisting of: wherein said heteroaryl is optionally substituted by one substituent selected from the group consisting of lower alkyl, which is optionally substituted by 1 to 3 substituents selected from the group consisting of aryl, cycloalkyl, heterocyclyl, lower alkoxy, hydroxyl, halogen, amino optionally substituted by one or two lower alkyl, COOH, COO-lower alkyl, oxo, cyano and heteroaryl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl, cycloalkyl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl, and heterocyclyl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl; and R 5 is selected from the group consisting of aryl and heteroaryl, wherein said aryl and said heteroaryl are optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl, or a pharmaceutically acceptable salt thereof.