Patent ID: 8679765

Claim:
A method comprising determining a level of a paraprotein that selectively binds to phosphorylated paratarg (stomatin-like protein 2) in a body fluid of a subject, optionally wherein the body fluid is blood, serum, lymph, saliva, urine or cerebrospinal fluid, and comparing said level of said paraprotein to a reference or control level, wherein if the level of said paraprotein in said body fluid is higher than the reference or control level, then the subject is indicated as having a gammopathy, and wherein if the level of said paraprotein in said body fluid is not substantially different from the reference or control level, then the subject is not indicated as having a gammopathy; optionally wherein the step of determining the level of the paraprotein comprises mixing or contacting said sample with a reagent that selectively binds to said paraprotein, said paraprotein selectively binding said paratarg, and/or contacting said sample with a device for assaying the level of one or more of said specific paraprotein/s.