Patent ID: 8779197

Claim:
A compound of formula III-A, III-B or III-C: or a pharmaceutically acceptable salt thereof, wherein: Ring A is phenyl or wherein ring A is optionally substituted with up to y occurrences of R 5 ; R 1 is C 1-6 aliphatic, wherein up to two carbon atoms other than the atom attached to the nitrogen or oxygen atom is optionally replaced with O, S, NR N , or C(O); each R 2 is independently hydrogen, or C 1-6 aliphatic, wherein up to two carbon atoms other than the atom attached to the nitrogen or oxygen atom is optionally replaced with O, S, NR N , or C(O); y is 0-4; each occurrence of R N is independently selected from hydrogen or a C 1-6 aliphatic group; R 3 is hydrogen, halogen, CN, CF 3 , NO 2 , or an optionally substituted group selected from C 1-6 aliphatic, C 1-6 cycloaliphatic, C 6-10 aryl, 5-6 membered heteroaryl, 4-7 membered heterocyclyl, aralkyl, —N(R′) 2 , —CH 2 N(R′) 2 , —OR′, —CH 2 OR′, —SR′, —CH 2 SR′, —C(O)R′, —COOR′, —NRCOR′, —CON(R′) 2 , —S(O) 2 R′, or —S(O) 2 N(R′) 2 ; each occurrence of R 5 is independently selected from hydrogen, halogen, CN, NO 2 , or an optionally substituted group selected from C 1-4 aliphatic, aryl, 5-6 membered heteroaryl, 4-7 membered heterocyclyl, aralkyl, —N(R′) 2 , —CH 2 N(R′) 2 , —OR′, —CH 2 OR′, —SR′, —CH 2 SR′, —COOR′, —NRCOR′, —CON(R′) 2 , or —S(O) 2 N(R′) 2 ; each occurrence of R is independently selected from hydrogen or a C 1-6 aliphatic group; each occurrence of R′ is independently selected from hydrogen or a C 1-8 aliphatic, C 6-10 aryl, a heteroaryl ring having 5-10 ring atoms, or a heterocyclyl ring having 3-10 ring atoms; and provided that the following compounds are excluded: 2-(4-methoxy-phenoxy)-5-nitro-N-(3-sulfamoyl-phenyl)-benzamide; Benzamide, N-[3-(methylsulfonyl)phenyl]-2-phenoxy-; Benzamide, N-[3-[(dimethylamino)sulfonyl]-4-methylphenyl]-2-phenoxy-; Benzamide, N-[5-[(diethylamino)sulfonyl]-2-methoxyphenyl]-2-phenoxy- Benzamide, N-[3-[(dimethylamino)sulfonyl]phenyl]-2-phenoxy-; Benzamide, N-[5-[(dimethylamino)sulfonyl]-2-methoxyphenyl]-2-phenoxy-; Benzamide, N-[3-(aminosulfonyl)phenyl]-2-(4-methoxyphenoxy)-5-nitro-; Benzamide, N-[2-chloro-5-(methylsulfonyl)phenyl]-2-phenoxy-; and Benzamide, N-[5-[(1-ethylpropyl)sulfonyl]-2-methoxyphenyl]-2-phenoxy-.