Patent ID: 7214381

Claim:
A pharmaceutical composition in the form of a solution, cream, lotion, spray, ointment, gel, aerosol, tablet, suppository or patch device for transdermal or transmucosal administration of one or more active agents to a subject, comprising as a permeation enhancing mixture: a fatty component in an amount of 0.1% to 20% by weight and comprising one of a saturated fatty alcohol of formula CH 3 —(CH 2 ) n —CH 2 OH, a saturated fatty acid of formula CH 3 —(CH 2 ) n —CH 2 COOH, an unsaturated fatty alcohol of formula CH 3 (C n H 2(n-1) )—OH, or a fatty acid of formula CH 3 (C n H 2(n-1) )—COOH, wherein n is an integer of between 8 and 22; and a vehicle comprising 5% to 75% by weight of a C 1 –C 4 alkanol, 0.5% to 50% of a polyalcohol, water, and up to 40% by weight of a monoalkylether of diethyleneglycol, with all weights calculated based on the total weight of the composition and provided that the total weights of the components does not exceed 100%, wherein the one or more active agents are selected from the group consisting of an androgen hormone, an antihypothyroid hormone, an antihypertensive agent, and a calcium regulator.