Patent ID: 8906900

Claim:
A compound of formula (V): or a pharmaceutically acceptable salt thereof, wherein: X 1 , X 2 , X 3 and X 4 are independently selected from the group consisting of N and CH, provided that at least one of X 2 , X 3 , and X 4 is not N; R 1 is hydrogen; L is —O— or —N(R)—; each R is independently hydrogen or optionally substituted C 1-6 aliphatic; L is a bond; Cy is an optionally substituted 5,6-bicyclic heteroaryl or an optionally substituted 6,6-bicyclic heteroaryl, wherein the bicyclic heteroaryl has 1-4 ring heteroatoms independently selected from nitrogen, oxygen and sulfur, and wherein the point of attachment is on the 6-membered ring; each of R 5 , R 6 , R 7 , and R 8 is hydrogen; each R x is independently selected from the group consisting of halo, —CN, optionally substituted aliphatic, —OR′, and —N(R″) 2 ; R′ is hydrogen or optionally substituted aliphatic; each R″ is independently hydrogen or optionally substituted aliphatic, or two R″ are taken together with their intervening atoms to form a heterocyclic ring; and n is 0, 1, or 2; wherein each instance of aliphatic is independently an alkyl, alkenyl, alkynyl, cycloalkyl, or cycloalkenyl group.