Patent ID: 8778973

Claim:
A method of treatment of a disease or disorder selected from the group consisting of obesity, dyslipidemia, hyperglycemia, type 1 diabetes and type 2 diabetes, said method comprising administering to a patient in need thereof an effective amount of a compound of formula (I), wherein R 1 is selected from the group consisting of: hydrogen, halogen, alkoxy, cyano, haloalkyl, alkylsulfanyl, aminosulfonyl, alkylsulfonyl, haloalkoxy and alkylcarbonyl, R 2 is selected from the group consisting of: hydrogen, halogen, alkoxy, cyano, haloalkyl, alkylsulfanyl, aminosulfonyl, alkylsulfonyl, haloalkoxy and alkylcarbonyl, R 3 is selected from the group consisting of: hydrogen, halogen, alkoxy, cyano, haloalkyl, alkylsulfanyl, aminosulfonyl, alkylsulfonyl, haloalkoxy and alkylcarbonyl, R 4 is selected from the group consisting of: hydrogen, halogen, alkoxy, cyano, haloalkyl, alkylsulfanyl, aminosulfonyl, alkylsulfonyl, haloalkoxy and alkylcarbonyl, R 5 is selected from the group consisting of: alkyl, hydroxyalkyl, cycloalkyl, phenylalkyl, halophenylalkyl, phenyl, substituted phenyl, thiophenyl and pyridinyl, wherein said substituted phenyl is phenyl substituted with one to three substituents independently selected from the group consisting of alkyl, alkoxy, halogen, cyano, haloalkyl, alkylsulfanyl, aminosulfonyl, alkylsulfonyl, haloalkoxy and alkylcarbonyl, R 6 is selected from the group consisting of: alkyl, hydroxyalkyl, cycloalkyl, phenylalkyl, halophenylalkyl, phenyl, substituted phenyl, thiophenyl and pyridinyl, wherein said substituted phenyl is phenyl substituted with one to three substituents independently selected from the group consisting of alkyl, alkoxy, halogen, cyano, haloalkyl, alkylsulfanyl, aminosulfonyl, alkylsulfonyl, haloalkoxy and alkylcarbonyl, R 7 is selected from the group consisting of: substituted phenyl, pyridinyl, substituted pyridinyl, thiazolyl, substituted thiazolyl and carboxy, wherein said substituted phenyl is phenyl substituted with one to three substituents independently selected from the group consisting of alkyl, hydroxy, alkoxy, carboxy, alkoxycarbonylalkyl, alkylaminocarbonyl, carboxyalkoxy, alkoxycarbonyl, alkoxycarbonylalkoxy and alkylsulfonylaminocarbonyl, and said substituted pyridinyl and said substituted thiazolyl are, respectively, pyridinyl and thiazolyl substituted with alkoxycarbonyl or carboxy; and n is 0 or 1; or a pharmaceutically acceptable salt or ester thereof; with the provisos that: R 5 and R 6 are not both methoxyphenyl at the same time; and when one of R 5 and R 6 is phenyl and the other one is phenyl, methylphenyl or alkoxyphenyl, R 7 is alkoxycarbonylphenyl.