Patent ID: 8329684

Claim:
A cephalosporin derivative represented by Chemical Formula 1, an in vivo hydrolysable ester thereof, wherein X is CR, N, or C substituted by Cl (C—Cl); Y is C 1 -C 2 alkyl, CH(CH 3 )CO 2 H, or C(CH 3 ) 2 CO 2 H; L is CH 2 or CH═CHCH 2 ; R 1 is NH 2 , NHR 11 or NH(CH 2 ) m NR 11 R 12 ; R 2 is NHR 21 , NH(CH 2 ) n COOH, NH(CH 2 ) n NR 21 R 22 , or NHC(═O)(CH 2 ) n NR 21 R 22 ; and R 3 is hydrogen or NH 2 , in which R is hydrogen or C 1 -C 3 alkyl; R 11 and R 21 are independently hydrogen, C 1 -C 3 alkyl, or a group selected from the group consisting of: R 12 and R 22 are independently hydrogen or C 1 -C 2 alkyl; and m and n are independently an integer of 1 to 6 or an in vivo hydrolysable ester thereof, an in vivo hydrolysable phosphate ester thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof.