Patent ID: 7012153

Claim:
A process for preparing a compound of formula I wherein; R is C 1 –C 6 alkyl; R 1 and R 2 each are independently C 1 –C 4 alkyl, or combine together with the nitrogen atom to which R 1 and R 2 are attached, to form piperidinyl, pyrrolidinyl, methylpyrrolidinyl, dimethylpyrrolidinyl, morpholino, or 1-hexamethyleneimino; and n is 2 or 3; or a pharmaceutically acceptable salt thereof, which comprises the step of: reacting a haloalkyl amine of formula III wherein; X is a halogen; and R 1 , R 2 , and n are as defined above, with a compound of formula IV wherein; R is C 1 –C 6 alkyl, in the presence of a base hydrated with 1–20% water and an appropriate solvent wherein said base is selected from the group consisting of potassium carbonate, sodium hydroxide, potassium hydroxide, lithium hydroxide, sodium carbonate and calcium carbonate.