Patent ID: 8445220

Claim:
A method for detecting the presence of the monomeric form of A-protein in a biological sample from a mammal, said sample containing both the polymeric and monomeric forms of A-protein, said method comprising the steps of: contacting the sample with an A-protein capture antibody bound to a support surface, said capture antibody recognizing an epitope of A-protein present on the monomeric form but not on the polymeric form of A-protein, removing excess sample from the support surface, contacting the support surface with an A-protein detectable antibody containing a detectable marker, said detectable antibody recognizing an epitope sequence consisting of SEQ ID NO:1, removing unbound antibody from the support surface, and determining the amount of detectable antibody bound to the support surface as a measure of the amount of the monomeric form of A-protein in the sample.