Patent ID: 7312226

Claim:
A compound having the following structure: or a stereoisomet, or pharmaceutically acceptable salt thereof, wherein: X is S, O or NH; Z is CH or N; with the proviso when X=NH then Z=CH; R 1 and R 2 are the same or different and are independently hydrogen, hydroxyl, halo, —CN, —NO 2 , —NH 2 , —R, —OR, —SCH 3 , —CF 3 , —C(═O)OR or —OC(═O)R, where R is alkyl or substituted alkyl; R 3 is hydrogen, —NH 2 , alkyl, —CN, or —NO 2 ; L 2 is selected from —NHCH 2 —, —NH—, —C(═S)NH—, —NHC(S)—, —C(═S)NHCH 2 , —NHC(═S)NH—, —NHC(═O)—, —NHC(═O)NH—; —S(═O) 2 —; and Cycl 2 is: