Patent ID: 8415505

Claim:
2-methylene-5-substituted-methylenecyclopentanone derivatives, wherein the 2-methylene-5-substituted-methylenecyclopentanone derivatives having the formula: wherein Q 1 is hydrogen, Q 2 is a straight or branched C1-C10 alkyl, C3-C7 cycloalkyl, or 5 to 10 membered heterocyclic group; wherein the heterocyclic group may contain 1 to 4 heteroatom selected from nitrogen, oxygen and sulfur, and optionally contains 1 or 2 carbon-carbon double bond or triple bond; wherein the heterocyclic group may be optionally substituted with 1 to 5 same or different R 1 , wherein R 1 is independently selected from hydroxyl, halogen, nitro, cyano, carbonyl, trifluoromethyl, trifluoromethoxy, C1-C4 alkyl, C1-C4 alkoxylmethyl, C1-C4 alkoxyl, N,N-di-C1-C4 alkylamino or C3-C7 cycloalkyl; and wherein cycloalkyl may contain 1 or 2 carbon-carbon double bond or triple bond; wherein Q 1 is hydrogen, Q 2 is substituted C6-C10 aryl, wherein aryl may be optionally substituted with 1 to 5 same or different R 2 ; wherein R 2 is independently selected from hydroxyl, halogen, carboxyl, amino, nitro, cyano, trifluoromethyl, trifluoromethoxy, C1-C4 alkyl, C3-C7 cycloalkyl, C1-C4 alkoxyl, C1-C3 alkylene dioxy, C1-C4 alkoxylmethyl, amino substituted with mono- or di-C1-C4 alkyl, C1-C4 alkylsulphonyl, or benzoyloxy substituted with R 1 ; wherein Q 1 is hydrogen, Q 2 is wherein R 3 is independently selected from hydroxyl, halogen, and C1-C4 alkyl; Ar 1 is C6-C10 aryl or 5 to 10 membered heteroaryl; wherein heteroaryl may contain 1 to 4 heteratoms selected from nitrogen, oxygen, or sulfur atoms; wherein aryl may be optionally substituted with 1 to 5 same or different R 1 ; or Q 1 and Q 2 are the same or different substituted C6-C10 aryl, wherein aryl may be optionally substituted with 1 to 5 same or different R 4 ; R 4 is independently selected from halogen, nitro, cyano, haloalkyl, C1-C4 alkyl or C1-C4 alkoxyl, wherein the 2-methylene-5-substituted-methylenecyclopentanone derivative is not 2-methylene-5-(4-methoxybenzylidene)cyclopentanone.