Patent ID: 7635678

Claim:
A composition comprising an isolated annexin protein selected from the group consisting of: (a) an annexin homodimer at least 95% identical to a protein selected from the group consisting of SEQ ID NO: 6, SEQ ID NO: 27, SEQ ID NO: 19, SEQ ID NO: 23, SEQ ID NO: 3-linker-SEQ ID NO: 3, SEQ ID NO: 12-linker-SEQ ID NO: 12, and SEQ ID NO: 15-linker-SEQ ID NO: 15, wherein the linker is at least one glycine-serine sequence; (b) an annexin heterodimer at least 95% identical to a protein selected from the group consisting of SEQ ID NO: 3-linker-SEQ ID NO: 12, SEQ ID NO: 3-linker-SEQ ID NO: 15, SEQ ID NO: 12-linker-SEQ ID NO: 15, SEQ ID NO: 12-linker-SEQ ID NO: 3, SEQ ID NO: 15-linker-SEQ ID NO: 3, and SEQ ID NO: 15-linker-SEQ ID NO:12, wherein the linker is at least one glycine-serine sequence; and (c) an annexin protein coupled to one or more polyethylene glycol (PEG) chains wherein the annexin protein is at least 95% identical to a protein selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 12, and SEQ ID NO: 15, wherein said isolated annexin protein has phosphatidylserine binding activity.