Patent ID: 7670625

Claim:
A pharmaceutical composition comprising, in admixture, (a) an active ingredient which is micronized formoterol fumarate dihydrate salt, and (b) a micronised pharmaceutically acceptable carrier/diluent, the content of formoterol being less than about 0.6% (w/w) the composition having a high storage stability such that the decomposition of formoterol in the composition will be less than 2.0% (w/w) when stored in a powder device at 40° C. and 75% relative humidity for 6 months when the content of formoterol is less than 0.6% (w/w) in the composition; wherein the composition is obtained by a process comprising (a) preparing a mixture of the micronised active ingredient and a portion of the micronised carrier/diluent, followed by (b) addition of further pre-micronised carrier/diluent which is mixed in at a pressure of less than 2 bar, followed by (c) either subjecting the mixture to agglomeration and spheronisation, or adding coarse carrier/diluent.