Patent ID: 7678391

Claim:
A method for controlling, treating and/or decreasing progression of cancer, malignancies, and/or tumor angiogenesis in a human subject, said method comprising: administering a low dose of a nitric oxide mimetic to said human subject, to control, treat and/or decrease progression of said cancer, malignancies, and/or tumor angiogenesis; wherein said nitric oxide mimetic is an organic nitrate; wherein said low dose is 3 to 10,000 fold lower than a dose of said nitric oxide mimetic that produces vasodilation in said human subject, and wherein said low dose of said nitric oxide mimetic does not induce substantial tolerance in said human subject wherein said low dose of a nitric oxide mimetic enhances the efficacy of, and/or decreases the resistance to an antimalignant therapeutic modality; and wherein said antimalignant therapeutic modality includes radiation therapy, thermal therapy, immunotherapy, or chemotherapy, or a combination thereof.