Patent ID: 7226791

Claim:
An isolated nucleic acid molecule comprising a polynucleotide sequence selected from the group consisting of: (a) an isolated polynucleotide encoding a polypeptide comprising amino acids 1–668 of SEQ ID NO: 5; (b) an isolated polynucleotide encoding a polypeptide comprising amino acids 2–668 of SEQ ID NO: 5; (c) an isolated polynucleotide comprising nucleotides 88 to 2109 of SEQ ID NO: 4, wherein said nucleotides encode a polypeptide corresponding to amino acids 1 to 668 of SEQ ID NO: 5; (d) an isolated polynucleotide comprising nucleotides 91 to 2091 of SEQ ID NO: 4, wherein said nucleotides encode a polypeptide corresponding to amino acids 2 to 668 of SEQ ID NO: 5; (e) ATCC Deposit No: PTA-6007; and (f) an isolated polynucleotide that hybridizes under stringent hybridization conditions to a polynucleotide sequence provided in (a)–(e), wherein said polynucleotide encodes a polypeptide that has guanylate binding activity wherein such stringent hybridization conditions are selected from the group consisting of (A) 7% SDS, 0.5 M NaPO 4 , 1 mM EDTA at 50° C. followed by washing in 0.1×SSC, 0.1% SDS at 65° C. and (B) 4×SSC at 65° C., followed by washing in 0.1×SSC at 65° C. for one hour.