Patent ID: 8329924

Claim:
A process for preparing a compound of formula A: said process comprising the steps of adding: an enol ether; an hydride donating agent; and an organic carboxylic acid; to a compound of formula B: wherein, Y 1 is chosen from a bond, C 1-6 alkyl, C 2-6 alkenyl or C 2-6 alkynyl; Y is chosen from COOR 16 , COCOOR 5 , P(O)OR a OR b , S(O)OR 5 , S(O) 2 OR 5 , tetrazole, CON(R 9 )CH(R 5 )COOR 5 , CONR 10 R 11 , CON(R 9 )—SO 2 —R 5 , CONR 9 OH or halogen, wherein R 9 , R 5 , R 10 and R 11 are each independently chosen from H, C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 6-14 aryl, C 3-12 heterocycle, C 3-18 heteroaralkyl, C 6-18 aralkyl; or R 10 and R 11 are taken together with the nitrogen to form a 3 to 10 membered heterocycle; R a and R b are each independently chosen from H, C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 6-14 aryl, C 3-12 heterocycle, C 3-18 heteroaralkyl and C 6-18 aralkyl; or R a and R b are taken together with the oxygens to form a 5 to 10 membered heterocycle; R 16 is chosen from H, C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 6-14 aryl, C 3-12 heterocycle, C 3-18 heteroaralkyl and C 6-18 aralkyl; R 1 is chosen from C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 6-14 aryl, C 3-12 heterocycle, C 3-18 heteroaralkyl, C 6-18 aralkyl or halogen; R 2 is chosen from C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 3-12 heterocycle, C 3-18 heteroaralkyl, or C 6-18 aralkyl; R 3 is chosen from H, C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 6-14 aryl, C 3-12 heterocycle, C 3-18 heteroaralkyl or C 6-18 aralkyl; Z is chosen from H, halogen, C 1-6 alkyl.