Patent ID: 6995139

Claim:
A pro-drug consisting of a cyclic undecapeptide in which the peptide chain comprises at least one amino acid residue of general formula (I) below: in which: the carbon atom C a constitutes one of the links of the undecapeptide ring; the substituents Y each represent a hydrogen atom or together constitute a bond; the substituents R 1 and R 3 represent, independently of one another, a hydrogen atom, an aralkyl group, an alkaryl group, a heteroalkyl group, a heterocyclic group, an alkylheterocyclic group, a heterocyclic alkyl group or a linear or branched alkyl group having from 1 to 6 carbon atoms, optionally substituted with at least one of the groups chosen from —COOH, —CONHR 8 , —NHC═NH(NH 2 ), —NHC═NR 8 (NH 2 ), —NH 2 , —NHR 8 , —NR 8 2 , —N + R 8 3 , —OH, —OPO(OR 8 ) 2 , —OPO(OH)(OR 8 ), —OPO(OH) 2 , —OSO(OR 8 ) 2 , —OSO(OH)(OR 8 ), —OSO(OH) 2 , and the various salified forms of these groups, each of the substituents R 8 representing, independently of one another, a linear or branched alkyl group having from 1 to 6 carbon atoms; the substituents R 2 and R 4 represent, independently of one another a hydrogen atom, an alkaryl group, or a linear or branched alkyl group having from 1 to 6 carbon atoms; the substituents R 5 and R 6 represent, independently of one another, a hydrogen atom, an aralkyl group, or a linear or branched alkyl group having from 1 to 6 carbon atoms; and the substituent R 7 represents an aralkyl group, an alkaryl group, a heteroalkyl group, a heterocyclic group, an alkylheterocyclic group, a heterocyclicalkyl group or a linear or branched alkyl group having from 1 to 6 carbon atoms, said groups being optionally substituted with at least one of the groups chosen from —COOH, —CONHR 8 , —NHC═NH(NH 2 ), —NHC═NR 8 (NH 2 ), —NH 2 , —NHR 8 , —NR 8 2 , —N + R 8 3 , —OH, —OPO(OR 8 ) 2 , —OPO(OH)(OR 8 ), —OPO(OH) 2 , —OSO(OR 8 ) 2 , —OSO(OH)(OR 8 ), —OSO(OH) 2 , and the various salified forms of these groups.