Patent ID: 8268315

Claim:
A method of inhibiting or reducing proliferation of a tumor cell comprising exposing the cell to an effective amount of an isolated antibody that binds human hepatocyte growth factor (HGF) comprising (i) an immunoglobulin light chain variable region comprising a CDR L1 comprising the amino acid sequence of SEQ ID NO. 18, a CDR L2 comprising the amino acid sequence of SEQ ID NO. 19, and a CDR L3 comprising the amino acid sequence of SEQ ID NO. 20; and (ii) an immunoglobulin heavy chain variable region comprising a CDR H1 comprising the amino acid sequence of SEQ ID NO. 15, a CDR H2 comprising the amino acid sequence of SEQ ID NO. 203, and a CDR H3 comprising the amino acid sequence of SEQ ID NO. 17; or an antigen binding fragment of the antibody, to inhibit or reduce proliferation of the tumor cell.