Patent ID: 7919477

Claim:
An oligodeoxynucleotide composition comprising a first oligodeoxynucleotide of 20 to 50 nucleotides in length, wherein the first oligodeoxynucleotide comprises the nucleic acid sequence set forth as SEQ ID NO: 106; and a second oligodeoxynucleotide of 16 to 50 nucleotides in length, wherein the second oligodeoxynucleotide comprises an unmethylated CpG motif, and wherein the second oligodeoxynucleotide comprises a sequence represented by the formula 5′ X 1 X 2 X 3 Pu 1 Py 2 CpG Pu 3 Py 4 X 4 X 5 X 6 (W) M (G) N -3′, wherein the central CpG motif is unmethylated, Pu is a purine nucleotide, Py is a pyrimidine nucleotide, X and W are any nucleotide, M is any integer from 0 to 10, and N is any integer from 4 to 10; wherein the first and the second oligodeoxynucleotides differ in their nucleic acid sequence and wherein the composition induces an immune response.