Patent ID: 7947830

Claim:
A compound of formula (I), or a pharmaceutically acceptable addition salt or a stereo-chemically isomeric form thereof, wherein R 1 is phenyl; wherein said phenyl is optionally substituted with one or two substituents each independently selected from halo, C 1-6 alkyl, C 1-6 alkyloxy, polyhaloC 1-6 alkyl, and phenyl; R 2 is hydrogen, —CH 2 —R 5 , trifluoromethyl, —C(═O)—R 6 , or —CH 2 —NR 7 R 8 ; wherein each R 5 is independently selected from hydrogen, hydroxy, C 1-6 alkyloxy, C 1-6 alkyloxyC 1-6 alkyloxy, C 1-6 alkylcarbonyloxy, piperazinyl, N-methylpiperazinyl, morpholinyl, thiomorpholinyl, imidazolyl or triazolyl; each R 6 is independently selected from hydroxy, C 1-6 alkyloxy, amino or mono- or di(C 1-6 alkyl)amino, C 1-6 cycloalkylamino, hydroxyC 1-6 alkylamino, piperazinyl, mono- or di(C 1-6 alkyl)aminoC 1-6 alkylamino N-methylpiperazinyl, morpholinyl or thiomorpholinyl; each R 7 and R 8 are independently selected from hydrogen, C 1-6 alkyl, C 1-6 alkylcarbonyl, C 1-6 alkylsulfonyl, or mono-or di(C 1-4 alkyl)aminosulfonyl; R 3 is hydrogen, hydroxymethyl, aminomethyl or mono- or di(C 1-6 alkyl)aminomethyl; and R 4 is hydrogen or C 1-6 alkyl.