Patent ID: 8710194

Claim:
A single-chain variable fragment (scFv), comprising: a heavy variable chain (VH); a light variable chain (VL); and a peptide linker joining said heavy variable chain to said light variable chain, wherein said fragment is directed against an epitope of the extracellular domain of the CD99 human protein consisting essentially of the amino acid sequence SEQ ID NO: 25 and wherein the VH chain comprises CDR1, CDR2 and CDR3 regions consisting essentially of amino acid sequences SEQ ID NO: 1, SEQ ID NO: 3 and SEQ ID NO: 4, respectively and the VL chain comprises CDR1, CDR2 and CDR3 regions consisting essentially of amino acid sequences SEQ ID NO: 2, SEQ ID NO: 5 and SEQ ID NO: 6, respectively.