Patent ID: 7329765

Claim:
A composition comprising a pharmaceutically acceptable excipient and a compound having the formula or the pharmaceutically acceptable salts thereof, wherein the subscript i is an integer of from 2 to 3, and in each ring having an X 1 , X 2 , and X 3 , one of X 1 , X 2 , and X 3 is a ring vertex independently selected from the group consisting of —O—, —S—, and —NR 2 —, and the other two of X 1 , X 2 , and X 3 are ring vertices independently selected from the group consisting of ═N— and ═CR 1 —; Z is O or N; n is 1 if Z is O and 2 if Z is N; each R 1 is independently H, F, Cl, Br, I, CN, OH, NO 2 , NH 2 , a substituted or unsubstituted (C 1 –C 12 )alkyl group, a substituted or unsubstituted (C 1 –C 12 )alkoxy group, or a substituted or unsubstituted (C 1 –C 12 )heteroalkyl group; each R 2 is independently H, a substituted or unsubstituted (C 1 –C 12 )alkyl group, or a substituted or unsubstituted (C 1 –C 12 )heteroalkyl group; or optionally, the group -Z(R 2 ) n is selected from the group consisting of wherein each subscript r is independently an integer of from 2 to 8 and each R 25 is independently selected from the group consisting of H, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 and CH(CH 3 ) 2 ; and each R 5 is independently H, F, Cl, Br, I, CN, OH, NH 2 , N(CH 3 ) 2 , a substituted or unsubstituted (C 1 –C 12 )alkyl group, a substituted or unsubstituted (C 1 –C 12 )alkoxy group, or a substituted or unsubstituted (C 1 –C 12 )heteroalkyl group; or optionally two adjacent R 5 groups are combined to form O—(CH(R 7 )) t —O, where t is 1 or 2 and each R 7 is independently H or a C 1 –C 6 alkyl, alkenyl, alkynyl, or acyl group; said compound having a basic group having a pK b of 12 or less or a quaternized nitrogen group.