Patent ID: 7026321

Claim:
A compound of Formula I: wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are hydrogen, lower alkyl, or —C(O)R; in which R is —OR 9 or —NR 9 R 10 , where R 9 and R 10 are hydrogen or lower alkyl; or R 1 and R 2 , R 3 and R 4 , R 5 and R 6 , R 7 and R 8 , when taken together with the carbon to which they are attached, represent carbonyl; or R 1 and R 5 , or R 1 and R 7 , or R 3 and R 5 , or R 3 and R 7 , when taken together form a bridging group —(CR 12 R 13 ) n —, in which n is 1, 2 or 3, and R 12 and R 13 are independently hydrogen or lower alkyl; with the proviso that (a) the maximum number of carbonyl groups is 1; (b) the maximum number of —C(O)NR 9 R 10 groups is 1; and (c) the maximum number of bridging groups is 1; T is oxygen, sulfur, or NR 11 , in which R 11 is hydrogen or lower alkyl; V is —N<; X 1 is hydrogen, optionally substituted lower alkyl, optionally substituted cycloalkyl, optionally substituted aryl, or optionally substituted heteroaryl; X 2 is optionally substituted aryl or optionally substituted heteroaryl; Y is optionally substituted dihydroheteroaryl; and Z 1 and Z 2 are independently optionally substituted alkylene of 1–4 carbon atoms.