Patent ID: 8703749

Claim:
A method of treating Friedreich's Ataxia in a subject in need thereof, comprising administering to a subject a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof: wherein: L is a linking group selected from the group consisting of —S(O) 2 —NH—(CR 2 ) x —, —S(O) 2 —NH—N═, —S(O) 2 —NH—N═(CR)— and —S(O) 2 —NH—C(O)—NH—(CR 2 ) y — wherein: R is H or C 1 -C 4 alkyl, and x and y are each independently 0, 1 or 2; B is a 5- or 6-membered aromatic ring having 1 or 2 optional nitrogen heteroatoms; each R a and each R b are independently C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, oxo, halo, —NO 2 , —CF 3 , —CN, —OR 9 , —SR 9 , —C(O)R 9 , —NHC(O)R 9 , —C(O)OR 9 , —OC(O)R 9 , —NR 10 R 11 , —C(O)NR 10 R 11 , —NHR 9 C(O)NR 10 R 11 , or —SO 2 NR 10 R 11 , aryl, arylalkyl, cycloalkyl, or heterocycle, wherein: R 9 , R 10 , and R 11 are independently H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, halo, aryl, arylalkyl, cycloalkyl, or heterocycle, each being optionally substituted with one to four substituents, and two R a or two R b together with the atoms to which they attach on the ring optionally form a ring; s is 0, 1, 2 or 3; and t is 1, 2, 3 or 4.