Patent ID: 7161002

Claim:
A composition of matter comprising an enantiomerically pure compound represented by Formula I: where: R 1 is hydrogen, alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl or substituted alkylheteroaryl; R 2 is alkyl, oxaalkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl or substituted alkylheteroaryl; R 3 is hydrogen, alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, substituted alkylheteroaryl, oxaalkyl, oxaalkylaryl, substituted oxaalkylaryl, R 9 O— or R 9 —NH—; R 4 is hydrogen, alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl or substituted alkylheteroaryl; R 5 , R 6 , R 7 and R 8 are independently hydrogen, hydroxy, alkyl, alkoxy, halogen, fluoroalkyl, nitro, cyano, substituted alkyl, amino, alkylamino, dialkylamino, alkylsulfonyl, alkylsulfonamido, sulfonamidoalkyl, sulfonamidoaryl, alkylthio, carboxyalkyl, carboxamido, aminocarbonyl, aryl or heretoaryl; and R 9 is alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl or substituted alkylheteroaryl, or a pharmaceutically acceptable salt thereof, having a detectable amount of one or more of the following: A) an enantiomerically pure compound of Formula 101: where X is hydrogen or a protecting group; B) a compound of Formula 103: C) a cyclo-dehydration reagent chosen from HMDS, phosphorous oxychloride, oxalyl chloride, thionyl chloride, Burgess' reagent, Ph 3 P/l 2 , a Vilsmeier reagent, and lithium hydroxide monohydrate.