Patent ID: 7517530

Claim:
A method for treating a human pediatric subject having insulin-like growth factor-1 deficiency (IGFD) comprising; administering to a human pediatric subject an effective amount of insulin like growth factor-1 (IGF-1) and growth hormone (GH), wherein the subject is characterized as follows: a) at the time of treatment or prior to initial treatment with IGF-1, has or had a height at least about 2 standard deviations (SD) below the normal mean height for a human pediatric subject of the same age and gender, b) at the time of treatment or prior to initial treatment with IGF-1, has or had a blood level of IGF-1 at least about 1 SD below normal mean levels for a human pediatric subject of the same age and gender, and c) the human pediatric subject does not have Laron syndrome or partial growth hormone insensitivity syndrome, wherein said administering is effective to treat IGFD in the human pediatric subject.