Patent ID: 7138393

Claim:
A compound of Formula (I) wherein W represents either a double-bonded O or two single bonded H; R 1 is selected from the group consisting of R, R 3 —X—R 2 —, R 3 —S(O)—, R 3 —S(O) 2 —, —SO 3 R 4 , —S(O) 2 N(R) 2 , and D-glucuronide, when W is hydrogen, or R 1 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, arylalkyl, heteroaryl, and heteroarylalkyl, when W is oxygen; R 2 is selected from the group consisting of alkylene, cycloalkylene, alkylene-X-alkylene, alkylene-X-cycloalkylene, cycloalkylene-X-alkylene, and cycloalkylene-X-cycloalkylene; R 3 is selected from the group consisting of alkyl, aryl, heteroaryl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, alkenyl-X-alkylene, cycloalkenyl-X-alkylene, and perfluoroalkyl; R 4 is selected from the group consisting of hydrogen and R3; R is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, monofluoroalkyl, perfluoroalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, hydroxyl-(C 1 –C 6 )alkyl, alkoxyalkyl, alkylthioalkyl, acyl, alkoxycarbonyl, —C(O)NH2, alkylaminocarbonyl, dialkylaminocarbonyl, alkylaminoalkyl, and dialkylaminoalkyl, and when two R groups are bonded to the same atom the two R groups together may form an alkylene group; X is selected from the group consisting of oxygen, —NR—, —S(O)m-,—C(O)—, —OC(O)—, —C(O)O—, —NRC(O)—, and —C(O)NR—; and m is an integer selected from 0, 1, and 2, and the racemates, enantiomers, and pharmaceutically acceptable salts thereof.