Patent ID: 7728016

Claim:
A compound of formula (IE) or a salt or N-oxide thereof: wherein R 1 has the formula (IIA): wherein R represents bromo, chloro, phenyl, C 1 -C 6 alkyl or phenyl(C 1 -C 6 alkyl) R 2 is hydrogen or a carboxamide radical of formula CONR B (Alk) n R A , wherein Alk is an optionally substituted divalent alkylene, alkenylene or alkynylene radical; n is 0 or 1; R B is hydrogen or a C 1 -C 6 alkyl or C 2 -C 6 alkenyl group; R A is hydroxy or an optionally substituted carbocyclic or heterocyclic ring; or R A and R B taken together with the nitrogen to which they are attached form an N-heterocyclic ring which may optionally contain one or more additional hetero atoms selected from O, S and N, and which may optionally be substituted on one or more ring C or N atoms; or a non aromatic carbocyclic or non aromatic heterocyclic ring wherein a ring carbon is optionally substituted, and/or a ring nitrogen is optionally substituted by a group of formula -(Alk 1 ) p -(Z) r (Alk 2 ) s -Q wherein in any compatible combination Alk 1 and Alk 2 are divalent C 1 -C 6 alkylene or C 2 -C 6 alkenylene radicals, p, r and s are independently 0 or 1, Z is —O—, —S—, —(C═O)—, —(C═S)—, —SO 2 —, —C(═O)O—, —C(═O)NR A —, —C(═S)NR A —; —SO 2 NR A , —NR A C(═O)—, —NR A SO 2 — or —NR A — wherein R A is hydrogen or C 1 -C 6 alkyl, and Q is hydrogen or a carbocyclic or heterocyclic radical; wherein each of Alk 1 , Alk 2 , and Q are optionally substituted with one or more substituents selected from (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, hydroxy, hydroxy(C 1 -C 6 )alkyl, mercapto, mercapto(C 1 -C 6 )alkyl, (C 1 -C 6 )alkylthio, halo (including fluoro and chloro), trifluoromethyl, trifluoromethoxy, nitro, nitrile (—CN), oxo, phenyl, —COOH, COOR A , —COR A , —SO 2 R A , —CONH 2 , —SO 2 NH 2 , —CONHR A , —SO 2 NHR A , —CONR A R B , —SO 2 NR A R B , —NH 2 , —NHR A , —NR A R B , —OCONH 2 , —OCONHR A , —OCONR A R B , —NHCOR A , —NHCOOR A , —NR B COOR A , —NHSO 2 OR A , —NR B SO 2 OR A , —NHCONH 2 , —NR A CONH 2 , —NHCONHR B , —NR A CONHR B , —NHCONR A R B , or —NR A CONR A R B , wherein R A and R B are independently a (C 1 -C 6 )alkyl group; and R 3 is hydrogen, optionally substituted cycloalkyl, cycloalkenyl, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl; or a carboxyl, carboxamide or carboxyl ester group, PROVIDED THAT at least one of R 2 and R 3 is present and is other than hydrogen.