Patent ID: 7820172

Claim:
A multi-domain peptide of formula I: wherein: each X is selected from SEQ ID NO 3-18 and RGD; R 1 is the single trifunctional amino acid residue; Each R 2 is the same or different and comprises from 0 to 5 amino acid residues covalently bonded to R 1 and X; Each R 3 is hydrogen (H) such that the terminal group is NH 2 , or is an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2 , NH 3 + , or NH group or a corresponding acylated derivative, or is from one to three amino acid residues with a terminal H, such that the terminal group is NH 2 , or an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2 , NH 3 + , or NH group or a corresponding acylated derivative; R 4 is OH such that the terminal group is a carboxyl, NH 2 , an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2 , NH 3 + , or NH group or a corresponding acylated derivative, or NH—R 3 ; Y is Ahx-Ahx-Ahx covalently bonded to R 1 and Z; and Z is selected from SEQ ID NO 19-24.