Patent ID: 7331251

Claim:
A device for in vitro testing of dissolution of a solid compound, wherein said device models an oral cavity, said device comprising: (a) an influx source having an inflow flow-rate; (b) a flow-through cell connected to the influx source, said flow-through cell having a capacity for receiving a volume of dissolution medium and the solid compound; (c) a sample holder for receiving a solid compound, said sample holder connected to the flow-through cell; (d) an efflux sink having an efflux flow-rate, said efflux sink being connected to the flow-through cell, wherein the dissolution medium is introduced to the flow-through cell at the inflow flow-rate and the dissolution medium is removed from the flow-through cell at the efflux flow-rate; (e) a filter disposed between the flow-through cell and the efflux sink to prevent undissolved compound from entering the efflux sink; and (f) a temperature-controlled adjustable rocker-assembly operably connected to the flow-through cell to rock the flow-through cell at a user-controlled temperature wherein dissolution medium flows over all surfaces of the solid compound on the sample holder.