Patent ID: 8580853

Claim:
A soluble aspirin composition, comprising: (i) granules including aspirin, heat-treated bicarbonate salt, pharmaceutically-acceptable resin and surfactant, in mixture with: (ii) crystalline particles of pharmaceutically-acceptable acid; and (iii) crystalline particles of heat-treated bicarbonate salt; wherein the soluble aspirin composition when introduced to water undergoes reaction of the crystalline particles of pharmaceutically-acceptable acid with the heat-treated bicarbonate salt and the aspirin to effect effervescing action and disintegration of the granules, with conversion of the aspirin to an acetylsalicylate compound of the bicarbonate salt cation, so that the composition rapidly dissolves in the water, without occurrence of undissolved residue, and wherein the pharmaceutically-acceptable acid comprises citric acid, and the surfactant comprises sodium laurel sulfate.