Patent ID: 7384943

Claim:
A compound of formula (I) wherein X is N; Y is NR 2 CH 2 , CH 2 NR 2 , NR 2 CO, CONR 2 , NR 2 SO 2 or NR 2 CONR 2 wherein R 2 is H or C 1 -C 6 alkyl; R 3 is H, C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl; R 3 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl or (CH 2 ) n -aryl, wherein aryl is a heteroaromatic ring containing one or two heteroatoms selected from N, O and S and which may be mono- or di-substituted with R 4 and/or R 5 ; wherein R 4 is selected from the group consisting of a) H, b) C 1 -C 6 alkyl, c) C 3 -C 6 cycloalkyl, d) halogen, e) CN, f) CF 3 , g) OH, h) C 1 -C 6 alkoxy, i) NR 6 R 7 , j) OCF 3 , k) SO 3 CH 3 , l) SO 3 CF 3 , m) SO 2 NR 6 R 7 , n) phenyl, o) phenyl-C 1 -C 6 alkyl, p) phenoxy, q) C 1 -C 6 alkylphenyl, r) an optionally substituted heterocyclic ring containing one or two heteroatoms selected from N, O, S, SO and SO 2 wherein the substituent(s) is(are) selected from C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, phenyl-C 1 -C 6 alkyl, (CH 2 ) m OR 9 wherein m is 2-6 and R 9 is H, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl or phenyl-C 1 -C 6 alkyl, and COR 8 , a) an optionally substituted heteroaromatic ring containing one or two heteroatoms selected from N, O and S wherein the ring substituent(s) is(are) selected from the group consisting of C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl and phenyl-C 1 -C 6 alkyl, and t) COR 8 ; wherein R 6 is H, C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl; R 7 is H, C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl; and R 8 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, CF 3 , NR 6 R 7 or phenyl; R 5 is H, OH, TF 3 , OCF 3 , halogen, C 1 -C 6 alkyl or C 1 -C 6 alkoxy; and n is 0-4; wherein the compound is an (R)-enantiomer, an (S)-enantiomer, or a racemate in the form of a tree base or a pharmaceutically acceptable salt thereof.