Patent ID: 6939874

Claim:
A compound of Formulas IIIa and IIIb wherein R 10 is selected from phenyl and 5-10 membered heterocyclyl; wherein R 10 is optionally substituted with 1-4 substituents selected from R 11 ; wherein R 11 is selected from C 1 -C 4 alkyl, C 2 -C 3 alkenyl, C 2 -C 3 alkynyl, C 3 -C 6 cycloalkyl, C 4 -C 6 cycloalkenyl, phenyl, 5-6 membered heterocyclyl, fluoro, chloro, bromo, CF 3 , —OR 12 , —OC(O)R 12 , —NR 12 R 12 , —COOR 2 , —C(O)R 12 , —C(O)NR 12 R 12 , —SO 2 R 12 , —SO 2 NR 12 R 12 , —NR 12 C(O)NR 12 R 12 , —NR 12 C(O)R 12 , —NR 12 (COOR 12 ), —NR 12 SO 2 NR 12 R 12 , —NR 12 SO 2 R 12 , —OC(O)NR 12 R 12 , C 1 -C 3 alkyl substituted with 1-3 substituents independently selected from optionally substituted phenyl and optionally substituted 5-6 membered heterocyclyl; and C 2 -C 3 alkenyl substituted with 1-3 substituents independently selected from optionally substituted phenyl and optionally substituted 5-6 membered heterocyclyl; wherein R 11 can be attached in either ring of the quinolyl substituent; wherein R 12 is selected from H, C 1-6 -alkyl, and phenyl optionally substituted with 1-3 substituents independently selected from C 1-4 -alkyl, chloro, fluoro, CF 3 , hydroxy, C 1-4 -alkoxy, amino, C 1-4 -alkylamino, carboxy, C 1-4 -alkoxycarbonyl, nitro, cyano, C 1-4 -alkylcarbonyl, C 1-4 -alkylaminocarbonyl, aminocarbonyl, aminosulfonyl and acetyl; or pharmaceutically acceptable derivatives thereof; provided in Formula IIIb R 10 is not 4-amino-2-methylquinol-6-yl when R 11 is 4-amino-2-methyl substitution.