Patent ID: 7504405

Claim:
A compound of the formula: wherein: m is 0, 1, 2, or 3; p is 1,2,3 or 4; R 3 is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, and heterocyclyl; R 5 is selected from the group consisting of hydrogen, alkyl, aryl, heterocyclyl, alkoxycarbonyl, aryloxycarbonyl, heterocyclyloxycarbonyl, aminocarbonyl, alkylcarbonyl, arylcarbonyl, heterocyclylcarbonyl, alkylsulfonyl, arylsulfonyl, and heterocyclylsulfonyl R 8 is selected from the group consisting of unsubstituted alkyl, substituted alkyl, aryl, and heterocyclyl; R 10 and R 11 are independently selected from the group consisting of hydrogen and C 1 to C 4 alkyl; wherein, said compound inhibits kinesin spindle protein with an IC 50 value of less than or equal to 25 μM; or pharmaceutically acceptable salts or stereoisomers thereof.