Patent ID: 7532935

Claim:
A method of treating an individual suffering from a mood disorder, the method comprising: coupling a first stimulator to a stimulation site comprising a volume of neural tissue in an area of the individual's brain selected from the group consisting of insula, subcallosal area, cingulate, thalamus, prefrontal cerebral cortex, brain stem, cerebellum, and white matter tracts leading to or from an aforementioned area; coupling a second stimulator to a cranial nerve of the individual; applying a first stimulation signal to said first stimulator such that said first stimulation signal causes modulation of the neuronal activity of neural tissue in said selected area of the brain; applying a second stimulation signal to said second stimulator such that said second stimulation signal causes modulation of the neuronal activity in said cranial nerve, wherein said modulations cause amelioration of the mood disorder.