Patent ID: 7427629

Claim:
An immunostimulatory composition comprising: an immune response modifier (IRM) portion of the formula: and having IRM activity; and a portion having antigenic activity that comprises: an antigenic portion, or a solid support to which an antigenic moiety is paired; wherein the immune response modifier portion is covalently coupled to the portion having antigenic activity through R 1 , R 2 , R 3 , or R 4 : wherein the immune response modifier portion comprises an imidazoquinoline amine; a tetrahydroimidazoquinoline amine; an imidazopyridine amine; an aryl ether-substituted imidazopyridine amine; a 1,2-bridged imidazoquinoline amine; a 6,7-fused cycloalkylimidazopyridine amine; an imidazonaphthyridine amine; a tetrahydroimidazonaphihyndine amine; an oxazoloquinoline amine; a thiazoloquinoline amine; an oxazolopyridine amine; a thiazolopyridine amine; an oxazolonaphthyridine amine; or a thiazolonaphthyridine amine; and wherein the antigenic portion or antigenic moiety comprises a polypeptide, a polynucleotide, or a lipopolysaccharide.