Patent ID: 8187468

Claim:
A method of making a packing material for liquid chromatography comprising: (a) forming a first mixture by combining sodium silicate and a compound of formula (I) wherein: A, B, D, E and G are each independently carbon or nitrogen; R 1 -R 5 are each independently absent, hydrogen, or alkyl (C≦4) , wherein if any of A, B, D, E, or G is nitrogen, then R 1 -R 5 is absent; R 6 is alkyl (C≦4) ; R 7 -R 10 are each independently hydrogen, or alkyl (C≦4) ; the bonds marked “a” and “b” are cis or trans to one another; and n=0 or 1, such that when n=0, then the ring marked as “B” is a five-membered ring, and when n=1, the ring marked as “B” is a six-membered ring; (b) adding Al 3+ to the first mixture to form a second mixture; (c) refluxing the second mixture; and (d) calcinating the second mixture to form the packing material.