Patent ID: 7834062

Claim:
A pharmaceutical composition for the treatment of malaria, which comprises a compound of formula I: or a pharmaceutically acceptable salt or enantiomer or diastereomer thereof, a second anti-malarial agent, and a pharmaceutically acceptable carrier; wherein: R 5 is hydrogen; R 1a and R 1 independently are tert-butyl, halo, C 1-6 alkoxy, C 3-10 cycloalkyl, C 6-10 aryl, or trihalovinyl, wherein said aryl is optionally substituted with 1-3 groups of R a ; each R 2 is hydrogen; R 3 and R 3a are independently hydrogen, halo, C 1-6 alkyl, C 3-10 cycloalkyl, or C 6-10 aryl, wherein said aryl and alkyl are each optionally substituted with 1-3 groups of R a ; R 4 is hydrogen; R a represents C 1-6 alkoxy, C 1-6 alkyl, CF 3 , nitro, amino, cyano, C 1-6 alkylamino, or halogen; and n represents 1-3.