Patent ID: 8618155

Claim:
A method for treatment of benign prostatic hyperplasia (BPH), an enlarged prostate, acute urinary retention, or symptoms thereof or reducing prostate size in a mammal comprising administering to a mammal in need of such treatment an effective amount of a compound of Formula I-B: wherein R 1 is selected from H, alkyl, heteroalkyl, aryl, and arylalkyl; R 2a is selected from aryl, alkyl, heteroalkyl, and arylalkyl; R 3 is selected from alkyl, heteroalkyl, and arylalkyl; R 4 is selected from H, alkyl, heteroalkyl, and arylalkyl; and R 3 and R 4 together with the nitrogen group form an aliphatic amine; or a pharmaceutically acceptable salt thereof.