Patent ID: 7521528

Claim:
A method for treating mammalian conditions characterized by decreases in bone mass, said method comprising administering to a subject in need thereof an effective bone mass-increasing amount of a biologically active peptide consisting essentially of the formula selected from: (a) X 01 ValX 02 GluIleX 03 LeuMetHisX 04 X 05 X 06 LysX 07 LeuAsnSerMetGlu ArgValGluTrpLeuArgLysLysLeuGlnAspValHisAsnTyr-NH 2 (SEQ ID NO:31); (b) a fragment of SEQ ID NO:31 containing the subsequence: X 01 ValX 02 GluIleX 03 LeuMetHisX 04 X 05 X 06 LysX 07 Leu; (c) pharmaceutically acceptable salts thereof; or (d) N- or C-derivatives thereof; wherein X 01 is Gly, Ser, Ala or Aib; X 02 is Ala, Ser or Aib; X 03 is Asp, Glu or Lys; X 04 is Asp, Glu or Lys; X 05 is Arg, Har or Leu; X 06 is Ala or Gly; X 07 is Trp or His.