Patent ID: 8471014

Claim:
A method for preparing a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R is H or F; and each of R 3 , R 4 , and R 5 is independently an optionally substituted alkyl or an optionally protected hydroxyl group; comprising providing a phenylpyrimidine compound of formula (II) wherein R is H or F, and each of R 3 , R 4 , and R 5 is independently an optionally substituted alkyl or an optionally protected hydroxyl group; and reacting the phenylpyrimidine compound of formula (II) with a urea derivative of formula A or B: wherein R 6 is an optionally substituted alkyl, optionally substituted aryl, optionally substituted saturated or unsaturated carbocycle, or optionally substituted saturated or unsaturated heterocycle; to provide a compound of formula (I); and optionally reacting the compound of formula (I) with a suitable acid to provide a pharmaceutically acceptable salt of the compound of formula (I).