Patent ID: 7279473

Claim:
A compound of Formula (I): or a salt thereof: wherein: D is N or CH R 1 is hydrogen, C 1 -C 6 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 1 -C 3 alkoxy, halogen, —CF 3 , hydroxy, cyano, —S(O) y C 1 -C 3 alkyl, or —NR 4 R 5 ; y is 0, 1, or 2; a is 1 or 2; R 2 is hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 3 -C 7 cycloalkyl, halogen, heterocyclyl, aryl, heteroaryl, cyano, azido, nitro, —OR 8 , —OR 6 R 8 , —R 6 R 7 , —R 6 R″, —OS(O) 2 R 9 , —S(O) y R 10 , —C(O)R 7 , —C(O)OR 7 , —C(O)NR 4 R 5 , —N(H)R′C(═NR 4 )NR 4 R 5 , —OC(O)NR 4 R 5 , —OC(O)OR 7 , —C(═NR 4 )NR 4 R 5 , —NR 4 R 5 , OC(O)R 7 , or —N(R 8 )C(O)R 8 ; R 3 is -(Q) p -(Q 1 ) where Q is O, N(R 8 ) or S(O) y , p is 0 or 1, y is 0, 1, or 2 and Q 1 is C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 1 -C 6 haloalkyl, aryl, aryl substituted with —C(O)N(H)R 6 NR 4 R 5 or —OC(H)(OH)R 6 NR 4 R 5 , heteroaryl, aralkyl, or —R 6 NR 4 R 5 ; R 4 and R 5 are independently hydrogen, C 1 -C 3 alkyl, C 3 -C 7 cycloalkyl, —C(O)R 9 , or R 4 and R 5 , together with the nitrogen atom to which they are bound, form a heterocyclyl; R 6 is alkylene, arylene, heteroarylene, C 3 -C 7 cycloalkylene, alkenylene, C 3 -C 7 cycloalkenylene, or alkynylene; R 7 is hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, —NR 4 R 5 , aryl, aralkyl, heteroaryl, cycloalkyl, heterocyclyl, —S(O) y R 10 , —C(O)R 8 , —C(O)OR 8 , —C(O)NR 4 R 5 , —S(O) 2 NR 4 R 5 , —N(H)R′C(═NR 4 )NR 4 R 5 , —OC(O)NR 4 R 5 , —OC(O)OR 8 , —C(═NR 4 )NR 4 R 5 , —NR 4 R 5 , or —N(R 8 )C(O)R 8 ; R 8 is hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, —NR 4 R 5 , aryl, aralkyl, heteroaryl, cycloalkyl, heterocyclyl, or —S(O) 2 R 9 ; R 9 is C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; R 10 is hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, —NR 4 R 5 , aryl, aralkyl, heteroaryl, cycloalkyl, heterocyclyl, —C(O)R 8 , —C(O)OR 8 , —C(O)NR 4 R 5 , —N(H)R′C(═NR 4 )NR 4 R 5 , —OC(O)NR 4 R 5 , —OC(O)OR 8 , —C(═NR 4 )NR 4 R 5 , —NR 4 R 5 , or —N(R 8 )C(O)R 8 ; R′ is C 1 -C 3 alkylene; and R″ is —OR 7 , —OC(O)NR 4 R 5 , —OC(O)OR 7 , or —OC(O)R 7 .