Patent ID: 8053577

Claim:
A compound of Formula I or a pharmaceutically-acceptable salt thereof, wherein R 1 is H, or C 1-4 alkyl; R 2 is H, halogen, or C 1-4 alkyl; R 3 is H, halogen, or C 1-4 alkyl, and R 4 is C 1-6 alkyl, aryl; or ═CR 3 R 4 is cyclopentylidene, cyclohexylidene, 1-methylpiperidin-4-ylidene, or inden-1-ylidene; R 5 is independently at each occurrence F, Cl, Br, CF 3 , R 9 , OR 9 , NR 9 R 10 , NO 2 , CN, COOR 9 , O 2 CR 9 , CONR 9 R 10 , NR 9 C(O)R 10 , heterocyclic group, aryl, or a group of Formula II R 6 is H, halogen, or C 1-4 alkyl R 7 is H, halogen, or C 1-4 alkyl; R 8 is H, C 1-4 alkyl group; R 9 is H, or C 1-6 alkyl; R 10 is H, or C 1-6 alkyl; R 11 is H, or C 1-4 alkyl; R 12 is H, or C 1-4 alkyl; m is 0, 1, or 2; when R 5 is F, Cl, Br, CF 3 , R 9 , OR 9 , NR 9 R 10 , NO 2 , CN, COOR 9 , O 2 CR 9 , CONR 9 R 10 , NR 9 C(O)R 10 , heterocyclic group, or aryl, n is 1, 2, 3, or 4; when R 5 is the group of Formula II, n is 0, 1, 2, 3, or 4; x is 0, 1, 2, 3, or 4.