Patent ID: 8440628

Claim:
A pharmaceutical composition comprising stable, physiologically-active ghrelin or its derivative in an aqueous solution which dissolves said ghrelin, and further comprising a pH adjuster, wherein: said aqueous solution has an acidic pH ranging from 3 to 6 to prevent the degradation of a hydrophobic group on the side chain of the serine or theronine at the third residue of said ghrelin, the pH adjuster comprises hydrochloric acid, sulfuric acid, nitric acid, boric acid, carbonic acid, bicarbonic acid, gluconic acid, sodium hydroxide, potassium hydroxide, aqueous ammonia, citric acid, monoethanolamine, lactic acid, acetic acid, succinic acid, fumaric acid, maleic acid, phosphoric acid, methanesulfonic acid, malic acid, propionic acid, trifluoroacetic acid, a salt thereof, or mixtures of said pH adjusters, and said composition is suitable for pharmaceutical administration to a human.