Patent ID: 8679502

Claim:
An isolated anti-hGM-CSF monoclonal antibody or antigen-binding fragment thereof, said antibody or antigen-binding fragment thereof comprising: (a) a heavy chain comprising a V H -CDR1-containing sequence, a V H -CDR2-containing sequence, and a V H -CDR3-containing sequence, wherein: (i) the V H -CDR1-containing sequence is SYGMH (SEQ ID NO: 4), (ii) the V H -CDR2-containing sequence is LTYHHGNRKFYADSVRG (SEQ ID NO: 5), and (iii) the V H -CDR3-containing sequence is ESMGAINDN (SEQ ID NO: 6); and (b) a light chain comprising a V L -CDR1-containing sequence, a V L -CDR2-containing sequence, and a V L -CDR3-containing sequence, wherein: (i) the V L -CDR1-containing sequence is IGNNNNIGSHAVG (SEQ ID NO: 7), (ii) the V L -CDR2-containing sequence is GRSPPS (SEQ ID NO: 8), and (iii) the V L -CDR3-containing sequence is STWDSSLSAVV (SEQ ID NO: 9).