Patent ID: 7737252

Claim:
A compound of general formula (I) wherein r=0 or 1 p=0 or 1 and r+p=1 when r=0 the R 1 is —(CH 2 ) n —CO— or —(CH 2 ) n —C 6 H 4 —CO— where n=1, 2, 3, 4 or 5, when r=1 then R 1 is one or more bridge-forming amino acids, X i =an amino acid functionalized with a chelate capable of binding a reporter suitable for in vivo imaging, X 2 and X 4 are independently cysteine, X 3 is N-methylarginine, X 5 is a hydrophobic amino acid, X 6 is cysteine, X 7 is a bond or linker optionally allowing for labeling with chelates as defined by X 8 , and optionally comprising one or more ethylene glycol units or any other spacer component, and X 8 is a chelate capable of binding a metal radionuclide or any other reporter suitable for in vivo imaging, or is NH 2 or is absent, q is 0, 1, 2, 3, 4, 5, 6, 7, 8, and one of the bridges, between R 1 and X 2 or between X 4 and X 6 , comprises a disulphide bond.