Patent ID: 6867310

Claim:
A method represented by Scheme 1: wherein G represents, independently for each occurrence, an electron withdrawing group selected from the group consisting of formyl, acyl, —C(O)OR, —C(O)NR 2 , nitro, nitroso, —S(O) 2 R, —SO 3 R, —S(O) 2 NR 2 , —C(NR)—R, —C(NOR)R, and —C(NNR 2 )—R; R represents, independently for each occurrence, hydrogen, alkyl, aryl, heteroalkyl, heteroaryl, halogen, alkylamino, arylamino, alkylthio, arylthio, alkoxy, aryloxy, or —(CH 2 ) m —R 8 ; Ar represents an aromatic or heteroaromatic moiety, X represents halogen, —OTf, —ONf, —OTs, —OMs, (alkyl)S(O) 2 O—, or (aryl)S(O) 2 O—; the transition metal catalyst consists essentially of palladium and one to four inclusive monodentate ligands selected from the group consisting of OAc, Cl, CH 3 CN, triphenylphosphine, tri(o-tolyl)phosphine, trimethylphosphine, triethylphosphine, tripropylphosphine, triisopropylphosphine, tributylphosphine, tricyclohexylphosphine, trimethyl phosphite, triethyl phosphite, tripropyl phosphite, triisopropyl phosphite, tributyl phosphite and tricyclohexyl phosphite; base represents a Bronsted base; R 8 represents independently for each occurrence a substituted or unsubstituted aryl, cycloalkyl, cycloalkenyl, heterocycle or polycycle; m, independently for each occurrence, is an integer selected from the range 0 to 8 inclusive; q is an integer selected from the range 1 to 3 inclusive; and p is an integer equal to (3-q).