Patent ID: 7998992

Claim:
A method for treating a 11β-hydroxysteroid dehydrogenase type 1 related disease, comprising administering to a subject an effective amount of a compound represented by the Formula (I): or its pharmaceutically acceptable salt, wherein R 1 is optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted non-aromatic heterocycle or optionally substituted non-aromatic heterocyclealkyl, X is —O—, —NR 3 —, —NR 3 C(═O)— or —NR 3 S(═O) 2 —, R 2 is optionally substituted aryl, optionally substituted arylalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, optionally substituted heterocycle or optionally substituted heterocyclealkyl, R 3 is hydrogen or optionally substituted alkyl, Y is —(CR 4 R 5 )n-, R 4 and R 5 are each independently hydrogen, optionally substituted alkyl, halogen or hydroxy, and n is an integer of 1 to 6, wherein the 11β-hydroxysteroid dehydrogenase type 1 related disease is at least one selected from the group consisting of hyperlipidemia, diabetes, obesity, arteriosclerosis, atherosclerosis, hyperglycemia and syndrome X.