Patent ID: RE39088

Claim:
An amide compound of the formula (I): wherein: R is a piperazinyl optionally substituted by lower alkyl, a piperidyl optionally substituted by lower alkyl or an amino wherein amino is optionally substituted by lower alkyl; A is a linear alkylene; X is an oxygen atom, a sulfur atom, —NH—or—CH 2 —; M is an arylene; R 1 , R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, provided at least one of R′, R 1 , R 2 , R 3 and R 4 is not a hydrogen atom, a hydroxy, a halogen atom, or —O—CO—R 11 ″′ wherein R 11 ″′ is lower alkyl optionally substituted by a substituent selected from the group consisting of amino, acyloxy and benzyloxycarbonyl, or phenyl optionally substituted by lower alkyl; R 5 is hydrogen atom; m is 1; R 6 is a phenyl and R 7 is —COO—R 12″ wherein R 12 ″′ is hydrogen atom, aralkyl, adamantyl, cyclohexylideneamino, cyclohexyl optionally substituted by lower alkyl, piperidyl optionally substituted by lower alkyl, or alkyl optionally substituted by a substituent selected from the group consisting of hydroxy, lower alkoxy, lower alkoxy lower alkoxy, lower alkoxycarbonyl, acyloxy, piperazinyl and amino optionally substituted by lower alkyl; or a pharmaceutically acceptable acid addition salt thereof.