Patent ID: 6919335

Claim:
A compound of formula (I) or enantiomers, diastereomers, tautomers, pharmaceutically acceptable salts and solvates thereof wherein: X 1 is C═O; X 2 is CR 3 ; X 3 is —NH—; X 4 is CR 4 ; X 5 is CR 5 ; X 6 is CR 6 ; R 1 is alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heterocycloalkyl, or heteroaryl; R 2 is a substituted or unsubstituted monocyclic heteroaryl group; R 3 is hydrogen, hydroxy, halogen, cyano, CO 2 R 7 , NR 8 R 9 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heterocycloalkyl or heteroaryl; R 4 , R 5 , and R 6 are independently selected from the group consisting of hydrogen, halogen, nitro, cyano, O—R 7 , NR 8 R 9 , SR 7 , S(O)R 7 , SO 2 R 7 , SO 3 R 7 , SO 2 NR 8 R 9 , CO 2 R 7 , C(O)NR 8 R 9 , C(O)alkyl, C(O)substituted alkyl, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl and substituted alkynyl; R 7 , R 10 , and R 11 , are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, alkynyl, cycloalkyl, substituted cycloalkyl, C(O)alkyl, C(O)substituted alkyl, C(O)cycloalkyl, C(O) substituted cycloalkyl, C(O)aryl, C(O)substituted aryl, C(O)Oalkyl, C(O)Osubstituted alkyl, C(O)heterocycloalkyl, C(O)heteroaryl, aryl, substituted aryl, heterocycloalkyl and heteroaryl; and R 8 and R 9 are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, alkynyl, C(O)alkyl, C(O)substituted alkyl, C(O)cycloalkyl, C(O)substituted cycloalkyl, C(O)aryl, C(O)substituted aryl, C(O)Oalkyl, C(O)Osubstituted alkyl, C(O)heterocycloalkyl, C(O)heteroaryl, aryl, substituted aryl, heterocycloalkyl, and heteroaryl or R 8 and R 9 taken together with the nitrogen atom to which they are attached complete a heterocycloalkyl or heteroaryl ring with the following proviso: (c) when R 2 is heteroaryl, at least one of the heteroatoms must be O.