Patent ID: 8440222

Claim:
A dermal or transdermal therapeutic system prepared for applying to the skin of a patient, said therapeutic system comprising: an active substance reservoir; an active substance-permeable membrane which delimits the active substance reservoir on one side; and a temperature dependent closing layer overlaying said membrane, said closing layer being impermeable to an active substance in said reservoir at a temperature lying below a skin temperature of the patient while being permeable to the active substance at or above the patient's skin temperature, said closing layer functioning as a switch, to be in the impermeable condition at temperatures below skin temperature, and switching to the permeable condition when said closing layer is applied to the skin of the patient, said closing layer consisting of a homogeneous mixture of materials consisting of beeswax and carnauba wax, with the proportion of beeswax being in the range of about 40 to 95% by weight and the proportion of carnauba wax being in the range of about 5 to 60% by weight.