Patent ID: 8236318

Claim:
A method for targeting an antigen to human DEC-205 in a human subject comprising administering to the human subject an antibody linked to an antigen, wherein the antibody comprises: (a) a heavy chain variable region CDR1 comprising SEQ ID NO: 29; a heavy chain variable region CDR2 comprising SEQ ID NO: 30; a heavy chain variable region CDR3 comprising SEQ ID NO: 31; a light chain variable region CDR1 comprising SEQ ID NO: 35; a light chain variable region CDR2 comprising SEQ ID NO: 36; and a light chain variable region CDR3 comprising SEQ ID NO: 37; (b) a heavy chain variable region CDR1 comprising SEQ ID NO: 17; a heavy chain variable region CDR2 comprising SEQ ID NO: 18; a heavy chain variable region CDR3 comprising SEQ ID NO: 19; a light chain variable region CDR1 comprising SEQ ID NO: 23; a light chain variable region CDR2 comprising SEQ ID NO: 24; and a light chain variable region CDR3 comprising SEQ ID NO: 25; (c) a heavy chain variable region CDR1 comprising SEQ ID NO: 5; a heavy chain variable region CDR2 comprising SEQ ID NO: 6; a heavy chain variable region CDR3 comprising SEQ ID NO: 7; a light chain variable region CDR1 comprising SEQ ID NO: 11; a light chain variable region CDR2 comprising SEQ ID NO: 12; and a light chain variable region CDR3 comprising SEQ ID NO: 13; (d) a heavy chain variable region CDR1 comprising SEQ ID NO: 41; a heavy chain variable region CDR2 comprising SEQ ID NO: 42; a heavy chain variable region CDR3 comprising SEQ ID NO: 43; a light chain variable region CDR1 comprising SEQ ID NO: 47; a light chain variable region CDR2 comprising SEQ ID NO: 48; and a light chain variable region CDR3 comprising SEQ ID NO: 49; (e) a heavy chain variable region CDR1 comprising SEQ ID NO: 53; a heavy chain variable region CDR2 comprising SEQ ID NO: 54; a heavy chain variable region CDR3 comprising SEQ ID NO: 55; a light chain variable region CDR1 comprising SEQ ID NO: 59; a light chain variable region CDR2 comprising SEQ ID NO: 60; and a light chain variable region CDR3 comprising SEQ ID NO: 61; or (f) a heavy chain variable region CDR1 comprising SEQ ID NO: 77; a heavy chain variable region CDR2 comprising SEQ ID NO: 78; a heavy chain variable region CDR3 comprising SEQ ID NO: 79; a light chain variable region CDR1 comprising SEQ ID NO: 83; a light chain variable region CDR2 comprising SEQ ID NO: 84; and a light chain variable region CDR3 comprising SEQ ID NO: 85, and wherein the antibody binds to human DEC-205 comprising SEQ ID NO:1.