Patent ID: 7375115

Claim:
A compound represented by the general formula (I): wherein X is CH or N; and Y is a group of the general formula (II): or a group of the general formula (II-a): or a group of the general formula (III): wherein a, b and c are each an integer of 0-6; Z is CH 2 or NH; W is O or S; T is O or N—R 15 wherein R 15 is H, a C1-C6 alkyl group, a benzyl group or a phenethyl group; R 1 is H, a C1-C6 alkoxycarbonyl group, a benzyloxy-carbonyl group, a carboxy group, a 2-phenyl-1,3-dioxan-5-yl group, a 2,2-dimethyl-1,3-dioxan-5-yl group, or a group of the general formula (IV): wherein d is an integer of 0-6; and R 3 , R 4 , and R 5 may be the same or different and are each independently H, —(CH 2 ) e R 6 or —(CH 2 ) f CONR 7 R 8 wherein e and f are each an integer of 0-6; R 6 is a hydroxy group, a C1-C6 alkanoyloxy group, a benzoyloxy group, a 2-furoyloxy group, a C1-C6 alkoxy C1-C6 alkoxy group, a C1-C6 alkoxycarbonylphenoxy group, a carboxyphenoxy group, a dicarboxyphenoxy group, a di C1-C6 alkoxy-carbonylphenoxy group, a dihydroxy C1-C6 alkylphenoxy group, an amino group, a C1-C6 alkoxycarbonylamino group, a C1-C6 alkylsulfonamido group, benzenesulfonamido group, a p-toluenesulfonamido group, a p-halobenzene-sulfonamido group, a carboxy group, a C1-C6 alkoxycarbonyl group, a carbohydroxamic acid group, a carbohydroxamic acid C1-C6 alkyl ester group, a cyano group, a 1H-tetrazol-5-yl group, a 1-(C1-C6 alkyl)-1H-tetrazol-5-yl group, a 2-(C1-C6 alkyl)-2H-tetrazol-5-yl group, a N 2 -hydroxycarbamidoyl group, a N 1 -(C1-C6 alkoxy-carbonyl)-N 2 -hydroxycarbamidoyl group, a 2H-5-thioxo-1,2,4-oxadiazol-3-yl group, a 2H-5-oxo-1,2,4-oxadiazol-3-yl group, a guanidino group, a di C1-C6 alkoxycarbonyl-guanidino group or a morpholinocarbonyl group; and R 7 and R 8 may be the same or different and are each independently H, a C1-C6 alkyl group, a C1-C6 alkanoyloxy C1-C6 alkyl group, a hydroxy C1-C6 alkyl group, a bis(C1-C6 alkanoyloxy C1-C6 alkyl)methyl group, a bis(hydroxy C1-C6 alkyl)methyl group, a tris(C1-C6 alkanoyloxy C1-C6 alkyl)methyl group, a tris(hydroxy C1-C6 alkyl)-methyl group, a carboxy C1-C6 alkyl group, a C1-C6 alkoxycarbonyl C1-C6 alkyl group, a N,N-bis(C1-C6 alkanoyloxy C1-C6 alkyl)carbamoyl C1-C6 alkyl group, a N,N-bis(carboxy C1-C6 alkyl)carbamoyl C1-C6 alkyl group, a C1-C6 alkylsulfonyl group, a carboxyphenyl group or a pyrazinyl group; and R 2 is H or a group of the above general formula (IV), or a pharmaceutically acceptable salt thereof.