Patent ID: 8232282

Claim:
A compound having a bicyclic pyrimidine structure of the following formula (I) or a pharmaceutically acceptable salt thereof: wherein R 1 is an optionally substituted cyclic lower alkyl group, an optionally substituted cyclic lower alkenyl group, an optionally substituted phenyl group, an optionally substituted naphthyl group, or a saturated or unsaturated optionally substituted heterocyclic group, R 2 is a hydrogen atom, an optionally substituted lower alkyl group, an optionally substituted lower alkenyl group, an optionally substituted lower alkynyl group, an optionally substituted cyclic lower alkyl group, an optionally substituted cyclic lower alkenyl group, an optionally substituted lower alkanoyl group, an optionally substituted phenylcarbonyl group, an optionally substituted phenyl group, or an optionally substituted naphthyl group, R 3 is a hydrogen atom, an optionally substituted lower alkyl group, an optionally substituted lower alkenyl group, an optionally substituted lower alkynyl group, an optionally substituted cyclic lower alkyl group, an optionally substituted cyclic lower alkenyl group, an optionally substituted phenyl group, or an optionally substituted naphthyl group, X is an oxygen atom, a sulfur atom, or —N(R 4 )—, R 4 is a hydrogen atom or a lower alkyl group, or R 2 and R 4 may combine each other to form a cyclic amino group, Y is the following (II), (III) or (IV): R 5 is a hydrogen atom or a lower alkyl group, Z is an oxygen atom or a sulfur atom, and m and n are each an integer of 1 or 2.