Patent ID: 7517645

Claim:
A method for screening for cervical high grade intraepithelial lesion (HSIL) in a human subject, the method comprising: a. obtaining a cervical sample containing a plurality of cervical cells from the subject; b. contacting the sample with a set of two or more chromosomal probes comprising chromosomal probes specific for loci 3q26 and 8q24 able to detect HSIL under conditions sufficient to enable hybridization of the probes to any chromosomes in the sample; and, c. detecting the hybridization pattern of the chromosomal probes to the plurality of cells in the sample, wherein said hybridization pattern is indicative of amplification of loci 3q26 and 8q24 and correlating said amplification of loci 3q26 and 8q24 with the presence of cervical HSIL in said subject.