Patent ID: 7414029

Claim:
A method for treating a human renal insufficiency disorder comprising administering a therapeutically effective amount of a peptide antagonist selected from the group consisting of: 213.19 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-D-Leu-Lys (SEQ ID NO: 2), 213.20 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Gly-D-Leu-Lys (SEQ ID NO: 3), 213.21 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-D-Leu-Lys-Lys (SEQ ID NO:4), 213.22 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Gly-D-Leu-Lys-Lys (SEQ ID NO:5), 213.23 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ser-D-Leu-Lys (SEQ ID NO:6), 213.24 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ser-D-Leu-Lys-Lys (SEQ ID NO: 7), 213.25 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-Lys (SEQ ID NO: 8), 213.26 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ser-Lys (SEQ ID NO: 9), 213.27 bip-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-D-Leu-Lys-Lys (SEQ ID NO: 10), 213.28 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-Leu-Lys-Lys (SEQ ID NO: 11), 213.29 bip-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-Leu-Lys-Lys (SEQ ID NO: 12) and 213.30 D-(bip)-D-Thr-D-Ser-D-Tyr-D-Glu-D-Ala-D-Leu-Gly-Lys-Lys (SEQ ID NO: 13), wherein bip is (4,4′) biphenylalanine, to a patient in need thereof.