Patent ID: 6989257

Claim:
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of: (a) SEQ ID NO: 43; (b) an amino acid sequence of a fragment of a SEQ ID NO: 43 having hydroxymethylglutaryl-CoA reductase (HMG-CoA reductase) activity; (c) an amino acid sequence of a polypeptide having HMG-CoA reductase activity, which is encoded by a polynucleotide that hybridizes to SEQ ID NO: 42 or a complement of SEQ ID NO: 42 under the following conditions: hybridization in 40% formamide, 1M NaCl, 1% sodium dodecyl sulfate (SDS) at 37° C., followed by at least one wash in 0.2×SSC at 60° C. for 20 minutes; and (d) an amino acid sequence of a polypeptide having HMG-CoA reductase activity, which is at least 95% identical to SEQ ID NO: 43.