Patent ID: 6906074

Claim:
A 2-phenylpiperazine derivative represented by the following formula (I) or a pharmaceutically acceptable salt, thereof, said 2-phenylpiperazine derivative being represented by the formula (I): wherein each of X 1 and X 3 is oxygen or two hydrogen atoms, X 2 is O, NH, NCH 3 , or CH 2 , n is an integer of 0 or 1, R 1 is hydrogen or lower alkyl and R 2 is hydrogen, cyano, tetrazolyl, aminotriazolyl, mesyl, t-butoxycarbonyl, or lower alkyl, wherein when R 2 is lower alkyl, the lower alkyl may be optionally substituted with a substituent selected from the following substituents (a) to (j) and/or oxo, (a) triazolonyl, (b) tetrazolyl, (c) dimethylaminomethyltriazolyl; (d) phosphotriazolonyl, (e) pyridyl, (f) dimethylamino, (g) cyano, (h) pyrrolidino, (i) amino, (j) phenyl, R 3 is hydrogen, halogen, lower alkyl or lower alkoxy, each of R 4 and R 5 is hydrogen, lower alkoxy or trifluoromethyl, and a broken line indicates a single or double bond.