Patent ID: 7674797

Claim:
A compound of the formula (I), its tautomeric or stereoisomeric form, or a physiologically acceptable salt thereof: wherein X represents O or S; R 1 represents hydrogen, halogen, hydroxy, nitro, cyano, C 1-6 alkoxy carbonyl, amino, C 1-6 alkylamino, di(C 1-6 alkyl)amino, C 1-6 alkanoyl, phenyl, C 1-6 alkyl optionally substituted by mono-, di- or tri-halogen, or C 1-6 alkoxy optionally substituted by mono-, di- or tri-halogen; R 2 represents hydrogen, halogen, hydroxy, nitro, cyano, C 1-6 alkoxy carbonyl, amino, C 1-6 alkylamino, di(C 1-6 alkyl)amino, C 1-6 alkanoyl, phenyl, C 1-6 alkyl optionally substituted by mono-, di- or tri-halogen, or C 1-6 alkoxy optionally substituted by mono-, di- or tri-halogen; R 3 represents hydrogen, halogen, hydroxy, nitro, cyano, amino, carboxy, tetrazolyl, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, C 1-6 alkanoyl, C 1-6 alkanoylamino, C 1-6 alkyl optionally substituted by mono-, di- or tri-halogen or hydroxy; R 4 represents wherein: R 71 represents hydrogen, or C 1-6 alkyl optionally substituted by amino, hydroxy, carboxy, pyrrolidinyl or piperidinyl, wherein said pyrrolidinyl and piperidinyl are optionally substituted by mono- or di-oxo; R 72 represents hydrogen, carboxy, C 1-6 alkanoyl, amino, (C 1-6 alkyl)amino, di(C 1-6 alkyl)amino, N-(C 1-6 alkyl)amino carbonyl, C 1-6 alkyl optionally substituted by hydroxy, carboxy, or mono-, di- or tri-halogen, C 1-6 alkoxy optionally substituted by mono-, di- or tri-halogen, pyrrolidinyl or piperidinyl, wherein said pyrrolidinyl and piperidinyl are optionally substituted by mono- or di-oxo; and Z 1 represents —[CH 2 ] p —, wherein p is 2.