Patent ID: 8709788

Claim:
An apparatus comprising: an integrated circuit chip configured and arranged as a one-sided biological sensing architecture that includes a substrate of the integrated circuit chip having a first side; a plurality of test sites that are recessed into the first side of the integrated circuit chip substrate and configured and arranged in a planar array; a plurality of photodiodes that are integrated into the recesses of the plurality of test sites and that are configured and arranged with a diffusion doping region having a dopant concentration and junction depth sufficient to detect firefly luciferase light produced during a pyrosequencing reaction within the plurality of test sites and generated from a sample contained within the test sites; an analog to digital converter circuit fabricated as part of the integrated circuit chip and configured and arranged to convert analog voltages from the plurality of photodiodes into digital values; and a memory circuit configured and arranged to store the digital values and that is fabricated as part of the integrated circuit chip.