Patent ID: 7501538

Claim:
The compound of Formula (I): wherein c is equal to 0; G is: —CO 2 R 1 ; wherein R 1 is -hydrogen; V is: —CH 2 —; X is —N(R 8 )CO—, wherein R 8 is: -hydrogen; Ar 1 is a mono-substituted phenyl group, wherein the substituent is selected from the group consisting of: -aryl, -arylene-alkyl, -D-aryl, -D-alkylene-arylene-alkyl, -arylene-D-alkyl, -arylene-D-R 10, and -D-alkylene-arylene-aryl, wherein R 10 is -aryl or -alkylene-aryl, and D is —O—, or —N(R 11 )—, wherein R 11 is: -hydrogen, -alkyl, or -aryl; Ar 2 is a substituted phenyl having 2 to 5 substituents wherein the phenyl is substituted at an ortho and a meta position on Ar 2 , relative to X; and wherein the substituents are independently selected from the group consisting of: -fluoro, -chloro, -bromo, iodo, -cyano, -nitro, - perfluoroalkyl, -T 1 -R 14 , -alkyl, -aryl, -arylene-alkyl, -T 1 -alkyl, -T 1 -alkylene-aryl, -T 1 -alkylene-arylene-aryl, -T 1 -alkylene-arylene-alkyl, -arylene-T 1 -alkyl, -T 1 -arylene-aryl, -T 1 -arylene-alkyl, -T 1 -aryl, -T 1 -alkylene-T 2 -R 14 and -T 1 -arylene-T 2 -R 14 ; wherein T 1 and T 2 are independently selected from the group consisting of —CH 2 —, —O—, —N(R 15 )—, —CON(R 15 )—, —N(R 15 )C(O), —N(R 15 )SO 2 , and —C(O)—O—; wherein R 14 and R 15 are independently selected from the group consisting of: -hydrogen, -alkyl, and -aryl, and wherein the alkyl, aryl alkylene, and arylene groups in Ar 1 , Ar 2 , and R 10 , R 11 , R 14 , and R 15 , may be optionally substituted 1 to 4 times with a substituent, wherein the substituents are independently selected from the group consisting of: a) -hydrogen; b) -fluoro; c) -chloro; d) -bromo e) -iodo; f) -cyano; g) -nitro; h) -perfluoroalkyl; i) -Q-R 18 ; j) -Q-alkyl; k) -Q-aryl; I) -Q-alkylene-aryl; m) -Q-alkylene-NR 19 R 20 ; and n) -Q-alkyl-W—R 21 ; wherein Q and W are independently selected from the group consisting of: —CH 2 —, —O—, —N(R 22 )—, —C(O)—, —CON(R 22 )—, —N(R 22 )C(O)—, —N(R 22 )CON(R 23 )—, —N(R 22 )C(O)O—, —OC(O)N(R 22 )—, —N(R 22 )SO 2 —, —SO 2 N(R 22 )—, —C(O)—O—, —O—C(O)—, and —N(R 22 )SO 2 N(R 23 )—, wherein R 18 , R 19 , R 20 , R 21 , R 22 , and R 23 are independently selected from the group consisting of: -hydrogen, -alkyl, -aryl, -arylene-alkyl, -alkylene-aryl, and -alkylene-arylene-alkyl, or a pharmaceutically acceptable salt thereof.