Patent ID: 7655683

Claim:
A compound of formula (I) wherein R 1 is selected from the group consisting of hydrogen, carboxy, alkyl, halogenated C 1-4 alkyl, aryl, aralkyl, heteroaryl, —C(O)-alkyl, —C(O)-(halogenated C 1-4 alkyl) and —C(O)O—C 1-4 alkyl; R 2 is selected from the group consisting of C 1-4 alkyl and halogenated C 1-4 alkyl; X is O or NH; R 3 is selected from the group consisting of C 1-4 alkyl, halogenated C 1-4 alkyl, —C(O)—C 1-4 alkyl, —C(O)—NR A —C 1-4 alkyl, benzyl, —C(O)-phenyl and —C(O)—NR A -phenyl; wherein R A is hydrogen or C 1-4 alkyl; R 4 absent or is selected from the group consisting of hydrogen, halogen, C 1-4 alkyl, halogenated C 1-4 alkyl, cyano, nitro, amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino, —O—C 1-4 alkyl, —S(O) 0-2 —C 1-4 alkyl, —NR B —C(O)—C 1-4 alkyl, benzyl, —O-phenyl, —C(O)-phenyl and —S(O) 0-2 -phenyl; wherein R B is hydrogen or C 1-4 alkyl; R 5 absent or is selected from the group consisting of hydrogen, halogen, C 1-4 alkyl, halogenated C 1-4 alkyl, cyano, nitro, amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino, —O—C 1-4 alkyl, —S(O) 0-2 —C 1-4 alkyl, —NR B —C(O)—C 1-4 alkyl, benzyl, —O-phenyl, —C(O)-phenyl and —S(O) 0-2 -phenyl; wherein R B is hydrogen or C 1-4 alkyl; R 6 is absent or selected from the group consisting of hydrogen, halogen, C 1-4 alkyl, halogenated C 1-4 alkyl, cyano, nitro, amino, —O—C 1-4 alkyl and —S(O) 0-2 —C 1-4 alkyl; or pharmaceutically acceptable salts and hydrates thereof.