Patent ID: 8454975

Claim:
A method for treating skin by administration of a neurotoxin solution to a human subject, comprising the steps of: a. defining a treatment volume having an outer surface and encompassing epidermis, dermis, and hypodermis; b. making a first plurality of punctures inside the treatment volume that penetrate through the epidermis and terminate within the dermis, and without penetrating into the hypodermis; c. applying the neurotoxin solution to the outer surface of the treatment volume to create a film of said neurotoxin solution on the outer surface, in which the neurotoxin solution comprises BoNTA and which is applied at 0.01 cubic centimeters per square centimeter of outer surface; d. making a second plurality of punctures into the treatment area that penetrate through the epidermis and terminate within the dermis, and without penetrating into the hypodermis; e. adding an additional amount of said neurotoxin solution to the outer surface; and f. allowing the neurotoxin solution to absorb into said treatment volume and penetrate into the hypodermis; and g. ensuring that the outer surface of the treatment volume is exposed to air but not wiped for at least two hours following the absorption of said neurotoxin solution.