Patent ID: 7345058

Claim:
A compound of the formula I: wherein: one of R 1 or R 2 is hydrogen or alkyl and the other is lower alkyl or (CH 2 ) p Y, wherein Y is a substituted or unsubstituted, saturated, partially unsaturated, or unsaturated mono-, bi- or tri-cyclic 5-10 membered cycloalkyl ring and p is 0 or 1, and wherein substituents on Y are lower alkyl, lower alkoxy, hydroxy, hydroxy-alkyl, alkyl-phenyl, phenyl-alkyl, pyridine or halogen, wherein if one of R 1 or R 2 is lower alkyl, said lower alkyl is not substituted with cyano, or R 1 and R 2 , together with the N atom to which they are attached, form a substituted or unsubstituted ring Z, wherein Z is a 5- to 7-membered monocyclic or 7- to 10-membered bicyclic saturated, partially unsaturated or unsaturated substituted or unsubstituted heterocyclic ring which contains the N atom to which R 1 and R 2 are attached, and optionally another hetero atom which is selected from N, O and S, wherein the substituted heterocyclic ring is mono- or di-substituted with lower alkyl, hydroxy, hydroxy-alkyl, alkyl-phenyl, phenyl-alkyl, pyridine or halogen; R 3 is an aromatic ring system selected from the group consisting of [2,2′]bithiophenyl, 1-methyl-indole, 2,3-dihydro-benzo[1,4]dioxin, benzo[1,3]dioxole, benzothiophene, dibenzofuran, furane, naphthalene, phenyl, biphenyl, quinoline, thianthrene and thiophene, wherein said aromatic ring may be unsubstituted or substituted with one or more amino, cyano, formyl, halo, hydroxy, hydroxymethyl, lower-acyl, lower-acyl-amino, lower-alkoxy, lower-alkoxy-carbonyl, 2-(lower-alkoxy-carbonyl)-ethenyl, lower-alkyl, lower-alkyl-thio, nitro, trifluoromethoxy or trifluoromethyl, wherein said phenyl ring may additionally be substituted with phenoxy or benzyloxy, or R 3 is: wherein Ar is a carbocyclic or heterocyclic aryl group which may be unsubstituted or substituted with one or more groups selected from the group consisting of halogen, lower alkyl, lower alkoxy, trifluoromethyl, cyano and nitro; and R 4 is unsubstituted lower alkyl; and pharmaceutically acceptable salts thereof.