Patent ID: 7309702

Claim:
A method for treating dementia of aging, the method comprising administering to a patient in need of such treatment an effective amount of a compound of the formula: wherein Ar′ is a phenyl or pyridyl substituted with one to three substituents selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkylthio, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkylhalo, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkenyl or halo; R 1 is hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkylthio; R 2 is phenyl, naphthyl or (C 3 -C 12 )cycloalkyl substituted with one or two substituents selected from the group consisting of hydrogen (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkylthio, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkylhalo, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkenyl or halo; R 3 is selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkylthio, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkylhalo, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkenyl or halo; and X is —(C═O)—; or a pharmaceutically acceptable salt, racemate, or optical isomer thereof.