Patent ID: 7371751

Claim:
A compound of the formula wherein R 1 is lower alkoxy, lower alkylamino-lower alkoxy, or —N(R a )R b ; R a is hydrogen, lower alkyl, carbamoyl-lower alkyl, hydroxy-lower alkyl, di-hydroxy lower alkyl, lower alkinyl, lower alkoxy, lower alkoxy-lower alkyl, di-lower alkyl amino-lower alkyl, cycloalkyl; or R a is phenyl-lower alkyl residue, wherein the phenyl moiety may optionally be mono-, di- or tri-substituted, independently, by lower alkyl, lower alkoxy or halogen; or R a is a 5- or 6-membered heteroaromatic ring containing one or two nitrogen atoms in the ring, with the said heteroaromatic ring being attached to the remainder of the molecule by lower alkylene; or R a is a 5-, 6- or 7-membered saturated heterocyclic ring optionally containing one or two heteroatoms selected from nitrogen, oxygen and sulfur, said heterocyclic ring being optionally mono-, di-, or tri-substituted, independently, by lower alkyl; R b is hydrogen, lower alkyl or lower alkoxy-lower alkyl; or R a and R b together with the nitrogen atom to which they are attached form a 4-, 5- or 6-membered saturated or unsaturated heterocyclic ring optionally containing a further heteroatom selected from nitrogen, oxygen and sulfur, said heterocyclic ring being optionally mono-, di-, or tri-substituted, independently, by lower alkyl, hydroxy, hydroxy-lower alkyl, lower alkoxy, lower alkoxy-lower alkyl, cyano, halogen, phenyl and/or benzyl; R 2 is hydrogen or lower alkyl; R 3 is phenyl mono-, di- or tri-substituted, independently, by lower alkoxy, halogen or perfluoro-lower alkoxy; and R 4 is a monocyclic aromatic ring optionally containing one or two nitrogen atoms in the ring, said ring being mono-, di- or tri-substituted, independently, by lower alkoxy, halogen or perfluoro-lower alkoxy; or a pharmaceutically acceptable salt thereof.