Patent ID: 8889141

Claim:
An isolated T-cell receptor (TCR) which binds to a peptide from latent membrane protein 2 (LMP-2) from the Epstein Barr Virus (EBV), said peptide having the amino acid sequence CLGGLLTMV (SEQ ID No. 1) when presented by a major histocampatability complex (MHC) molecule, the TCR comprising an α chain and a β chain, wherein the α chain comprises three complementarity determining regions (CDRs) having the following amino acid sequences: (SEQ ID No. 4) CDR1α-TSDQSYG (SEQ ID No. 5) CDR2α-QGSYDEQ (SEQ ID No. 2) CDR3α-FCAMREGSGSARQLTFGSGTQLTVLPD and wherein the β chain comprises three complementarity determining regions (CDRs) having the following amino acid sequences: (SEQ ID No. 6) CDR1β-SSHAT (SEQ ID No. 7) CDR2β-FNYEAQ (SEQ ID No. 3) CDR3β-ASSLGPAGIQETQYFGPGTRLLVL.