Patent ID: 7097882

Claim:
A substrate for immobilizing a physiological material comprising a substrate material coated with a primer layer and an immobilization layer over the primer layer, the primer layer comprising a first oligomer capable of enhancing the attachment between the substrate material and the immobilization layer; and the immobilization layer comprising a second oligomer having a functional group capable of immobilizing a physiological material, wherein the primer layer comprises an oligomer formed from a mixture of compounds represented by the formula 1 and formula 2: M(OR 1 ) n (1) (M′R 2 m ) p (R 3 ) q (2) wherein M and M′ are each independently selected from the group consisting of 4B, 3A, 4A, and 5A group elements of the Periodic Table; R 1 is selected from hydrogen atoms, C 1-20 alkyl groups and C 6-12 aromatic groups; R 2 is selected from hydroxy, halogen atoms, C 1-20 alkoxy groups and C 6-12 oxyaromatic groups; R 3 is a methylene or a phenyl group, optionally substituted with a C 1-6 substituent; n is a value ranging from 3 to 4 and is determined depending upon the valence of M; m is a value ranging from 2 to 3 and is determined depending upon the valence of M′; p is a numerical value ranging from 2 to 4; and q is a numerical value ranging from 1 to 20, wherein the weight ratio of the compound of formula (1) to the compound of formula (2) ranges from 50:50 to 95:5.