Patent ID: 7378438

Claim:
A multifunctional β-agonist compound having reactive oxygen species (ROS) scavenger groups and nitric oxide (NO) donor groups being ROS scavenger and NO donor of Formula 1: or its salt or a solvate thereof or an optical isomer thereof, wherein R 1 is —SNO; R 2 is ROS scavenger group or a NO donor group connected to the —NH group via a linker made of C 5 -C 8 cyclic alkyl, or straight or branched C 1 -C 15 alkyl in which one carbon atom is optionally replaced by oxygen or nitrogen, wherein said ROS scavenger group is selected from a nitroxide free radical, alkenyl, sulfhydryl or dithiol moiety in oxidized or reduced form, and aryl, and wherein said NO donor group is selected from —ONO, —ONO 2 , —SNO, and —NONOate or R 2 is C 5 -C 8 cyclic alkyl, or straight or branched C 1 -C 15 alkyl; R 3 and R 4 together form a substituted 5 to 7-membered saturated heterocycle having 1 or 2 heteroatoms independently selected from nitrogen, oxygen, and sulfur, wherein one of said nitrogen atoms being optionally substituted by oxygen to form a nitroxide radical; R 5 is selected from the group consisting of —H and straight or branched chain C 1 -C 15 alkyl; and whereas any of said alkyl groups is optionally substituted with one or more functional groups selected from hydroxyl, bromo, fluoro, chloro, iodo, mercapto thio, cyano, alkylthio, aryl, carboxyl, carbalkoyl, alkenyl, nitro, amino, alkoxyl, or amido; wherein R 2 is said ROS scavenger if said saturated heterocycle does not have the nitrogen atom substituted by oxygen.