Patent ID: 7883694

Claim:
A method for augmenting soft or hard tissue within a mammalian body, comprising: (a) providing a first crosslinkable component, wherein the first crosslinkable component is a synthetic polylysine; (b) providing a second crosslinkable component, wherein the second crosslinkable component is poly(alkylene oxide) having n electrophilic groups capable of reaction with the synthetic polylysine to form covalent bonds, wherein n is 2, 3 or 4, and each electrophilic group is independently succinimidyl ester, succinimidyl carbonate, sulfosuccinimidyl ester, maleimido, epoxy, isocyanato, thioisocyanato, or ethenesulfonyl; (c) applying the first and second crosslinkable components to the tissue; and (d) allowing the first and second crosslinkable components to crosslink in situ, wherein the first and second crosslinkable components are biocompatible, synthetic, and nonimmunogenic.