Patent ID: 7915433

Claim:
A 3,6-substituted pyran group-containing compound having the structural formula: wherein A, A′ are each phenyl; B is optionally substituted C 4 -C 14 aryl; Z is a chemical bond; R is H or C 1-8 alkyl; W is selected from the group consisting of hydrogen and —OH, wherein when W is hydrogen, B is described by the following formula: p is 0-6; R 1 is C 1-4 alkyl, C 2-6 alkenyl, C 2-6 optionally halogenated alkynyl, C 2-6 hydroxyalkynyl, —CN, —COOR 4 , —OH, —NO 2 , —NH 2 , —NHR 4 , —SO 2 NH 2 , —NHSO 2 R 8 , —OCF 3 or —OR 8 ; R 4 is H, C 1-18 alkyl, C 5-10 cycloalkyl, or C 2-18 alkylene R 8 is C 1-8 alkyl, C 5-6 cycloalkyl,C 2-8 alkenyl, or a 5 or 6-member aromatic ring including heterocyclic rings; n is 0; and m is 1 or a pharmaceutically acceptable derivative or salt thereof.