Patent ID: 8772510

Claim:
A compound of formula (I) wherein: X and X 1 are each independently CR 4 or N; Y and Y 1 are each independently C or N; Z and Z 1 are each independently CR 6 , NR 7 , N, O or S; R 1 and R 2 are each independently selected from hydrogen, C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -haloalkyl, C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl, heterocycloalkyl and C 1 -C 7 -alkyl optionally substituted by aryl or heteroaryl or R 1 and R 2 , together with the nitrogen atom to which they are attached, form a bicyclic ring system or a heterocycloalkyl optionally substituted by 1 to 3 substituents independently selected from the group consisting of hydroxyl, halogen, C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy, C 1 -C 7 -haloalkyl and oxo; R 3 is hydrogen or C 1 -C 7 -alkyl; R 4 is hydrogen, C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -haloalkyl or halogen; R 5 is aryl or heteroaryl each of which is optionally substituted by C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, halogen, C 1 -C 7 -haloalkyl, C 1 -C 7 -alkoxy, hydroxyl, C 1 -C 7 -hydroxyalkyl, C 1 -C 7 -alkoxyalkyl, acetyl, cyano, or amino optionally substituted by one or two C 1 -C 7 -alkyl groups; R 6 is hydrogen, halogen, C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -alkoxy, C 1 -C 7 -haloalkyl, C 1 -C 7 -alkoxyalkyl, heterocycloalkyl, aryl, heteroaryl, or C 1 -C 7 -alkyl optionally substituted by aryl, heteroaryl, heterocycloalkyl, or cycloalkyl; or R 5 and R 6 , together with the Y 1 and Z atom to which they are attached, form aryl or heteroaryl each of which is optionally substituted by C 1 -C 7 alkyl, halogen, C 1 -C 7 -alkoxy, or C 1 -C 7 -haloalkyl; R 7 is hydrogen, halogen, C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -alkoxy, C 1 -C 7 -haloalkyl, C 1 -C 7 alkoxyalkyl, heterocycloalkyl, aryl, heteroaryl, or C 1 -C 7 -alkyl optionally substituted by aryl, heteroaryl, heterocycloalkyl, or cycloalkyl; or R 5 and R 7 , together with the Y 1 and Z atom to which they are attached, form aryl or heteroaryl each of which is optionally substituted by C 1 -C 7 alkyl, halogen, C 1 -C 7 -alkoxy, or C 1 -C 7 haloalkyl; and W is ethylene which is optionally substituted by C 1 -C 7 alkyl.