Patent ID: 7291636

Claim:
A compound of the formula (I): wherein R 1 is: C 1-6 alkyl optionally substituted by one or two substituents selected from hydroxyl, trifluoromethyl, C 1-6 alkoxy, C 1-6 thioalkyl, thiophene or phenyl; or C 3-7 cycloalkyl, thiophene, benzothiophene, pyridinyl, furanyl or phenyl; said phenyl being optionally substituted by one to three substituents selected from halogen, C 1-6 alkyl, C 1-6 alkoxy, hydroxyl, methylenedioxy, phenoxy or benzyloxy; R 2 and R′ 2 are independently of one another selected from: hydrogen, halogen, hydroxyl, C 1-3 alkoxy, C 1-3 alkyl, C 3-7 cycloalkyl, or O—C(O)—C 1-6 alkyl; or R 2 and R′ 2 taken together form an oxo group; R 3 is: hydrogen or C 1-6 alkyl optionally substituted by hydroxyl or C 1-3 alkoxy; R 4 and R 5 are independently of one another selected from: hydrogen, C 1-7 alkyl optionally substituted by C 3-7 cycloalkyl or phenyl; or C 3-7 cycloalkyl, phenyl, naphthyl or —C(X)R 6 ; said C 3-7 cycloalkyl and phenyl being optionally substituted by one or more groups selected from halogen, hydroxyl, C 1-3 alkyl, C 1-3 alkoxy, phenyl, phenoxy or benzyloxy; provided that at least one of R 4 or R 5 is —C(X)R 6 ; wherein X is oxygen or sulfur; R 6 is C 1-6 alkoxy, hydroxyl or —NR 7 R 8 ; ps and wherein R 7 and R 8 are independently of one another selected from: hydrogen, C 1-6 alkyl optionally substituted by C 3-7 cycloalkyl, C 3-7 cycloalkenyl, phenyl or pyridinyl; or C 3-7 cycloalkyl, C 1-6 alkoxy or phenyl; said C 3-7 cycloalkyl and phenyl being optionally substituted by C 1-3 alkyl, hydroxyl, C 1-3 alkoxy or halogen; or R 7 and R 8 taken together with the nitrogen atom to which they are attached form aziridine, azetidine, pyrrolidine, piperidine or morpholine; or an addition salt with an acid of said compound of formula (I), or a hydrate or a solvate of said compound of formula (I).