Patent ID: 7629337

Claim:
A method to treat HIV or rheumatoid arthritis in a human or animal subject, comprising administering to a subject in need of such treatment an effective amount of a compound of formula I or pharmaceutically acceptable acid addition salts, and any stereoisomeric forms and mixtures of stereoisomeric forms thereof; wherein, W is a nitrogen atom and Y is void or, W is a carbon atom and Y═H; R 1 to R 7 may be the same or different and are independently selected from hydrogen or straight, branched or cyclic C 1-6 alkyl, where R 1 and R 2 together may form ═O; R 8 is an optionally substituted heterocyclic group or an optionally substituted aromatic group; Ar is an aromatic or heteroaromatic ring each optionally substituted at single or multiple, non-linking positions with electron-donating or withdrawing groups; n and n′ are independently 0-2; X is a group of the formula: wherein Ring A is an optionally substituted pyridine ring, and P is the nitrogen atom of said pyridine ring; Ring A is bound to group W from any position through group V; wherein V is a chemical bond or V is a (CH 2 ) n″ group, (where n″=0-2) or V is a C═O group; and wherein Z is selected from the group consisting of: a hydrogen atom; an optionally substituted C 1-6 alkyl group; a C 0-6 alkyl group substituted with an optionally substituted aromatic or heterocyclic group; and an optionally substituted C 0-6 alkylamino or C 3-7 cycloalkylamino group; thereby treating HIV or rheumatoid arthritis in said subject.