Patent ID: 7906509

Claim:
A compound of Formula III, wherein: R is H, —R 1 , —R 1 —R 2 —R 3 , —R 1 —R 3 , or —R 2 —R 3 ; R 1 is aryl, heteroaryl, cycloalkyl, or heterocycloalkyl, and is optionally substituted with one or more lower alkyl, hydroxy, hydroxy lower alkyl, lower alkoxy, halo, nitro, amino, amido, cyano, oxo, or halo-lower alkyl; R 2 is —C(═O), —O, —C(═O)O, —C(═O)NR 2′ , or —S(═O) 2 ; R 2′ is H or lower alkyl; R 3 is H or R 4 ; R 4 is lower alkyl, amino, aryl, arylalkyl, alkylaryl, heteroaryl, alkyl heteroaryl, heteroaryl alkyl, cycloalkyl, alkyl cycloalkyl, cycloalkyl alkyl, heterocycloalkyl, alkyl heterocycloalkyl, or heterocycloalkyl alkyl, and is optionally substituted with one or more lower alkyl, hydroxy, hydroxy lower alkyl, lower alkoxy, halo, nitro, amino, amido, acyl, cyano, or halo-lower alkyl; X is CH or N; Y 1 is H, lower alkyl, or lower haloalkyl; each Y 2 is independently halogen or lower alkyl, wherein lower alkyl is optionally substituted with one or more substituents selected from the group consisting of hydroxy, lower alkoxy, lower haloalkoxy, lower haloalkyl, carboxy, amino, and halogen; n is 0, 1, 2, or 3; Y 3 is H, halogen, or lower alkyl, wherein lower alkyl is optionally substituted with one or more substituents selected from the group consisting of hydroxy, lower alkoxy, amino, and halogen; m is 0 or 1; Y 4 is Y 4a , Y 4b , Y 4c , or Y 4d ; Y 4a is H or halogen; Y 4b is lower alkyl, optionally substituted with one or more substituents selected from the group consisting of haloalkyl, halogen, hydroxy, amino, cyano, and lower alkoxy; Y 4c is lower cycloalkyl, optionally substituted with one or more substituents selected from the group consisting of lower alkyl, lower haloalkyl, halogen, hydroxy, hydroxyl lower alkyl, amino, cyano, and lower alkoxy; and Y 4d is amino, optionally susbstituted with one or more lower alkyl, alkoxy lower alkyl, or hydroxy lower alkyl; or a pharmaceutically acceptable salt thereof.