Patent ID: 7029700

Claim:
A method for making micronized particles of an agent, comprising: (a) dissolving a macromolecular material in an effective amount eta solvent, to form a first solution; (b) dissolving the agent in an effective amount of a solvent, to form a second solution; (c) adding the second solution to the first solution to form an emulsion and thereby micronize the particles of the agent; (d) freezing the emulsion; (e) drying by vacuum the frozen emulsion to form solid micronized particles of the agent dispersed in solid macromolecular material; and (f) then, dissolving the macromolecular material having dispersed therein solid micronized particles of the agent in an effective amount of a solvent for the macromolecular material to form a dispersion of solid microparticles of agent in the solvent, wherein the solvent is a non-solvent for the agent.