Patent ID: 7153970

Claim:
A process for making 3-ethyl 5-methyl (+/−) 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulfonate (amlodipine benzenesulfonate) comprising reacting 3-ethyl 5-methyl (+/−) 2-[2-(N-tritylamino)ethoxymethyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate with benzenesulfonic acid in the presence of ethanol media, at a temperature of from about 20° C. to a reflux temperature, followed by isolation and purification of amlodipine benzenesulfonate as a product thereof.