Patent ID: 7405043

Claim:
A method of evaluating responsiveness of a subject to a drug, comprising providing a nucleic acid sample from a subject; determining a single nucleotide polymorphism genotype of a gene group that includes the human ADAR, CASP5, FGF1, ICSBP1, IFI44, PIK3CG, TAP2, and TGFBRAP1 genes; and comparing the single nucleotide polymorphism genotype of the human ADAR, CASP5, FGF1, ICSBP1, IFI44, PIK3CG, TAP2, and TGFBRAP1 genes with a predetermined single nucleotide polymorphism genotype for each of human ADAR, CASP5, FGF1, ICSBP1, IFI44, PIK1CG, TAP2, and TGFBRAP1 genes, whereby the subject is predicted to be responsive or non-responsive to the drug if the single nucleotide polymorphism genotype is identical to a predetermined single nucleotide polymorphism genotype of the human ADAR, CASP5, FGF1, ICSBP1, IFI44, PIK3CG, TAP2, and TGFBRAP1 genes.