Patent ID: 7470713

Claim:
A compound having the formula: its enantiomers, diastereomers, or pharmaceutically acceptable salts thereof wherein: n is 1; Y is O or S; A and B are independently —CH or CO, provided that A and B are not both CO; W is N; R 1 , R 3 , and R 6 are each H or C 1 to C 6 alkyl; R 2 is H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, halo, amino, aminoalkyl, alkoxy, thioalkoxy, nitro, aryl, alkoxyalkyl, thioalkoxyalkyl, aralkyl, —CN, —C(O)R 8 , —CO 2 R 8 , —CONR 9 R 10 , —CO 2 NR 11 R 12 , —NR 13 CONR 14 R 15 , —NR 16 SO 2 R 17 , —SO 2 NR 18 R 19 , —C(NR 20 )NR 21 R 22 ; R 4 and R 5 are each H, —NH-Z, —NH-Z-aryl, wherein Z is selected from the group consisting of C 1 -C 4 alkyl, alkenyl, and alkynyl; Z optionally having one or more hydroxy, thiol, alkoxy, thioalkoxy, amino, halo, NR 23 SO 2 R 24 , —CO, —CNOH, —CNOR 26 , —CNNR 27 , —CNNCOR 28 and —CNNSO 2 R 29 ; and R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 24 , and R 26 are independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, hydroxy, alkoxy, aryl, and alkyl-R 25 wherein R 25 is alkenyl, hydroxy, thiol, alkoxy, thioalkoxy, amino, alkylamino, dialkylamino, aryl, cyano, halo, sulfoxy, sulfonyl, —NR 27 COOR 28 , —NR 29 C(O)R 30 , —NR 31 SO 2 R 32 , SO 2 NR 31 R 32 —C(O)NR 33 R 34 , and R 27 , R 28 , R 29 , R 30 , R 31 , R 32 , R 33 and R 34 are, independently, hydrogen, alkyl, or cycloalkyl.