Patent ID: 6869957

Claim:
A compound of the formula wherein: R 1 is piperazinyl or piperidinyl; which may be substituted with halo, C 1 -C 4 alkoxy, trifluoromethyl, amino, C 1 -C 4 alkylamino, di(C 1 -C 4 alkyl)amino, phenyl, piperazinyl, C 3 -C 8 cycloalkyl, benzyl, C 1 -C 4 alkyl, piperidinyl, pyrimidinyl, C 2 -C 6 alkanoylamino, pyrrolidinyl, C 2 -C 6 alkanoyl, or C 1 -C 4 alkoxycarbonyl; any one of which phenyl, piperazinyl, C 3 -C 8 cycloalkyl, benzyl, C 1 -C 4 alkyl, piperidinyl, pyrrolidinyl, C 2 -C 6 alkanoyl, or C 1 -C 4 alkoxycarbonyl groups may be substituted with halo, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, trifluoromethyl, amino, C 1 -C 4 alkylamino, di(C 1 -C 4 alkyl)amino, or C 2 -C 4 alkanoylamino; R 2 is —CO—R 6 ; R 6 is hydrogen, C 1 -C 4 alkyl, C 1 -C 3 haloalkyl, phenyl, C 1 -C 3 alkoxy, C 1 -C 3 hydroxyalkyl, amino, C 1 -C 4 alkylamino, di(C 1 -C 4 alkyl)amino, or —(CH 2 ) q —R 7 ; q is 0 to 3; R 7 is phenoxy, phenylthio, piperazinyl, piperidinyl, pyrrolidinyl, morpholinyl, indolinyl, indolyl, benzothienyl, benxofuranyl, quinolinyl, isoquinolinyl, phenyl-(C 1 -C 4 alkyl)-, quinolinyl-(C 1 -C 4 alkyl)-, isoquinolinyl-(C 1 -C 4 alkyl)-, benzoyl-C 1 -C 3 alkyl; any one of which R 7 groups may be substituted with halo, trifluoromethyl, C 1 -C 4 alkoxy, amino, C 1 -C 4 alkylamino, di(C 1 -C 4 alkyl)amino, C 2 -C 4 alkanoylamino, phenyl, piperazinyl, C 3 -C 8 cycloalkyl, benzyl, piperidinyl, pyridinyl, pyrimidinyl, pyrrolidinyl, C 2 -C 6 alkanoyl, C 1 -C 4 alkyl, or C 1 -C 4 alkoxycarbonyl; any of which phenyl, piperazinyl, C 3 -C 8 cycloalkyl, benzyl, piperidinyl, pyridinyl, pyrimidinyl, pyrrolidinyl, C 2 -C 6 alkanoyl, C 1 -C 4 alkyl, or C 1 -C 4 alkoxycarbonyl groups may be substituted with halo, trifluoromethyl, C 1 -C 4 alkoxy, C 1 -C 4 alkyl, C 1 -C 4 alkylamino, di(C 1 -C 4 alkyl)amino, or C 2 -C 4 alkanoylamino; R a is halo, C 1 -C 3 alkoxy, C 1 -C 3 alkylthio, nitro, trifluoromethyl, or C 1 -C 3 alkyl; and Rb is hydrogen, halo, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, trifluoromethyl, amino, C 1 -C 4 alkylamino, or di(C 1 -C 4 alkyl)amino; or pharmaceutically acceptable salt or solvate thereof.