Patent ID: 8729110

Claim:
A compound having Formula I, its enantiomers, diastereoisomers, tautomers or a pharmaceutically acceptable salt thereof, wherein: X is S, SO or SO 2 ; R 1 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, NO 2 , CN, C(O)R 13 or OR 14 ; R 2 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, NO 2 , CN, C(O)R 13 or OR 14 ; R 3 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, NO 2 , CN, C(O)R 13 or OR 14 ; R 4 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, NO 2 , CN, C(O)R 13 or OR 14 ; R 5 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, NO 2 , CN, C(O)R 13 or OR 14 ; R 6 is H, halogen, OR 14 , substituted or unsubstituted C 1-8 alkyl; R 7 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, NO 2 , CN, C(O)R 13 or OR 14 ; R 8 is CH, S, O, N, NH or CH 2 ; R 9 is CH or CH 2 ; R 10 is hydrogen, halogen, substituted or unsubstituted C 1-8 alkyl, C(O)R 13 or OR 14 ; R 11 is H or substituted or unsubstituted C 1-8 alkyl; R 12 is OPO 3 H 2 , carboxylic acid, PO 3 H 2 , —P(O)MeOH, —P(O)(H)OH or OR 14 ; a is 0 or 1; b is 1, 2, 3, 4, 5 or 6; R 13 is OH or C 1-8 alkyl; R 14 is H or C 1-8 alkyl; when a is 1 then when a is 0 then and R 8 is S, O, NH or CH 2 .