Patent ID: 7875650

Claim:
A method of facilitating or enhancing the bioavailability of a bioactive agent or drug, the activity of which is diminished by P-gp170 or CYP450 in a patient or subject, said method comprising co-administering with said bioactive agent or drug to said patient or subject an effective amount of at least one bioavailability enhancing agent according to the formula: where R 5 is an optionally substituted phenyl or benzyl group, an acyl group, a C 1 -C 20 alkyl or ether group, a phosphate, diphosphate, triphosphate or phosphodiester group; R 6 and R 7 are each independently H, (C 1 -C 12 )alkyl, (C 2 -C 13 )acyl, or an optionally substituted phenyl or benzyl or together with the oxygen atoms to which they are attached form a —OCR 1 R 2 O— group wherein each of R 1 and R 2 is independently H, a C 1 -C 3 alkyl group or an optionally substituted phenyl or benzyl group; and R 8 is H, OH, an O-acyl group, a C 1 -C 4 alkyl or alkoxy group, F, Cl, Br or I; or a pharmaceutically acceptable salt thereof.