Patent ID: 7553819

Claim:
A compound of Formula I wherein R 1 is selected from the group consisting of CO 2 H and tetrazole; R 2 is C 1-6 alkyl; is a single or a double bond such that when is a single bond, X is selected from the group consisting of O, S, NH, CH 2 , OC(O) and O(CO)NH, and when is a double bond, X is selected from the group consisting of O, S, N and CH; R 3 is selected from the group consisting of a small oligosaccharide or saccharide, a small peptide, a small oligocarbamate, a small molecule which binds to a serum amyloid P component (SAP) surface adjacent to a Ca 2+ -dependent binding site, (LA) m , (LA) m MFC and when is a double bond and X is O or S, R 3 is non-existent; n is an integer between, and including, 1 and 20; m is an integer between and including, 1 and 20; LA is a linker arm selected from the group consisting of arylene, a peptide chain, oligocarbamate, C 2-60 straight, branched or cyclic alkylene and C 2-60 straight, branched or cyclic alkenylene, wherein in both alkylene and alkenylene, one or more of the carbons may optionally be replaced with an O, S, N and/or NR 6 and optionally interrupted by arylene, and the linker arms can optionally be functionalized at one or more positions with a group selected from aryl, heteroaryl, heterocyclo, C 3-8 cycloalkyl, OH, O-aryl, O-heteroaryl O-heterocyclo, O—C 3-8 cycloalkyl and O—C 1-6 alkyleneheterocyclo, wherein the aryl, heteroaryl, cycloalkyl and heterocyclo may each be independently optionally substituted; R 6 is selected from the group consisting of H and C 1-6 alkyl; MFC is a multifunctional core group; and pharmaceutically acceptable salts, hydrates, solvates and prodrugs thereof.