Patent ID: 8088905

Claim:
An isolated nucleic acid encoding an antibody comprising: (i) a V H domain that comprises three CDRs having the amino acid sequences as set out in: (a) SEQ ID NOs: 23, 24, and 25, (b) SEQ ID NOs: 29, 30, and 31, (c) SEQ ID NOs: 35, 36, and 37, or (d) SEQ ID NOs: 50, 51, and 52; or (ii) a V L domain that comprises three CDRs having the amino acid sequences as set out in: (e) SEQ ID NOs:26, 27, and 28, (f) SEQ ID NOs: 32, 33, and 34, (g) SEQ ID NOs:38, 39, and 40, or (h) SEQ ID NOs:53, 54, and 55, wherein the antibody specifically binds an epitope within the extracellular domain of human or mouse PD1.