Patent ID: 8058265

Claim:
A compound of the formula: wherein the solid line to C(1â€²) provides that the compound is an E- or Z-geometrical isomer respecting the 2-propylidene segment, wherein the C(20) is the stereochemical center, wherein the provides an R or S configuration, wherein n is 1 or 2, wherein Y 1 is a member selected from the group consisting of hydrogen, deuterium and a first hydroxy-protecting group, wherein Y 2 is a member selected from the group consisting of hydrogen, deuterium and a second hydroxy-protecting group, wherein X is a third hydroxy-protecting group, wherein R 1 is a member selected from the group consisting of hydrogen, deuterium and methyl, wherein R 2 is a member selected from the group Consisting of hydrogen, deuterium and methyl, wherein R 3 is a member selected from the group consisting of hydrogen, deuterium and methyl and wherein is a member selected from the group consisting of and , and esters thereof.