Patent ID: 7888508

Claim:
A compound of formula (I) wherein R is selected from the group consisting of —R a , —COR a , —CONR a R b , —SO 2 R a and —COOR a ; R 1 is —NR c R d or —OR c ; wherein R a , R b , R c and R d are the same or different and are each independently hydrogen or a group, optionally further substituted, which is straight or branched C 1 -C 6 alkyl, straight or branched C 2 -C 6 alkenyl, straight or branched C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyl C 1 -C 6 alkyl, an aryl, aryl C 1 -C 6 alkyl, a heterocycle and heterocycle C 1 -C 6 alkyl or, taken together with the nitrogen atom to which they are bonded, R a and R b as well as R c and R d form a 1,3-dioxolane, pyran, pyrrolidine, pyrroline, imidazoline, imidazolidine, pyrazolidine, pyrazoline, piperidine, piperazine, morpholine, tetrahydrofuran, hexamethyleneimine, 1,4-hexahydrodiazepine or azetidine group; R 2 is a group, optionally further substituted, selected from the group consisting of straight or branched C 1 -C 6 alkyl, straight or branched C 2 -C 6 alkenyl, straight or branched C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyl C 1 -C 6 alkyl, aryl, aryl C 1 -C 6 alkyl, heterocycle and heterocycle C 1 -C 6 alkyl; wherein any of R a , R b , R c , R d or R 2 is independently optionally substituted by halogen, nitro, oxo groups, carboxy, cyano, alkyl, perfluoroalkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl, heterocyclyl, amino groups, carbonylamino groups, hydroxy groups, carbonyl groups or sulfurated groups; wherein said aryl is selected from the group consisting of phenyl, indanyl, biphenyl, α- or β-naphthyl, pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl, indolyl, imidazolyl, imidazopyridyl, 1,2-methylenedioxyphenyl, thiazolyl, isothiazolyl, pyrrolyl, pyrrolyl-phenyl, furyl, phenyl-furyl, benzotetrahydrofuranyl, oxazolyl, isoxazolyl, pyrazolyl, chromenyl, thienyl, benzothienyl, isoindolinyl, benzoimidazolyl, quinolinyl, isoquinolinyl, quinoxalinyl, benzofurazanyl, 1,2,3-triazolyl and 1-phenyl-1,2,3-triazolyl; wherein said heterocycle is selected from the group consisting of 1,3-dioxolane, pyran, pyrrolidine, pyrroline, imadazoline, imidazolidine, pyrazolidine, pyrazoline, piperidine, piperazine, morpholine, tetrahydrofuran, hexamethyleneimine, 1,4-hexahydrodiazepine and azetidine; or isomers, tautomers, carriers, and pharmaceutically acceptable salts thereof.