Patent ID: 8029560

Claim:
A medical product for occluding a venous vessel, comprising: an occlusive construct comprising a remodelable material configured for deployment within a venous vessel to fill at least a luminal segment of the venous vessel so as to occlude the venous vessel, wherein the remodelable material is a dried collagenous extracellular matrix material harvested to retain and retaining bioactive components native to a source tissue for the dried collagenous extracellular matrix material and which is effective to induce angiogenesis when deployed within the vessel, wherein the dried collagenous extracellular matrix material is effective to promote the ingrowth of patient tissue into the lumen of the venous vessel and lead to angiogenesis and wherein the occlusive construct includes one or more dried sclerosants that are effective to injure the lining of the venous vessel so as to enhance the ingrowth of patient tissue into the occlusive construct and promote occlusion of the venous vessel, the dried collagenous extracellular matrix material comprising at least 80% by weight collagen on a dry weight basis, including uniaxial or multiaxial oriented fibers, and including at least about 3% retained non-collagenous solids from the source tissue, the non-collagenous solids including said bioactive components.