Patent ID: 8802128

Claim:
A biodegradable intraocular implant comprising: a combination of biodegradable poly(D,L,-lactide-co-glycolide) and poly(D,L,-lactide) polymers in a 1:2 ratio, respectively, and an alpha-2 adrenergic receptor agonist and a steroid in a 60:40 weight ratio of drug to polymer, wherein the alpha-2 adrenergic agonist and steroid are arranged in interleaved alternate layers; wherein the alpha-2 adrenergic receptor agonist is selected from the group consisting of apraclonidine, clonidine, oxymetazoline, epinephrine, norepinephrine, dexmedetomidine, mivazerol, xylazine, medetomidine, and brimonidine; and wherein the steroid is selected from the group consisting of cortisone, prednisolone, fluorometholone, dexamethasone, medrysone, loteprednol, fluazacort, hydrocortisone, betamethasone, prednisone, methylprednisolone, triamcinolone hexacatonide, paramethasone acetate, triamcinolone acetonide, diflorasone, fluocinonide, and mixtures thereof.