Patent ID: 7229993

Claim:
A compound of Formula I: or pharmaceutically acceptable salt, or solvate thereof, wherein: A is selected from C═O or C—R 4 ; where: when A is C═O, the bond between N and A is a single bond, and R 3 is present; when A is C—R 4 , the bond between N and A is a double bond, and R 3 is not present; and R 4 is hydrogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; R 1 is selected from the group consisting of: (i) phenoxyphenyl; (ii) benzyloxyphenyl; (iii) phenylthiophenyl; (iv) benzylthiophenyl; (vi) naphthalenyl; wherein the terminal aryl ring of each of (i) to (iv), and any part of the ring (vi) are optionally substituted by one or more of: halogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; with the proviso that when: R 1 is naphthalenyl, optionally substituted by one or more of: halogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl, and A is C—R 4 , where R 4 is hydrogen or C 1-6 alkyl; R 2 is not: (i) hydrogen; or (ii) C 1-6 alkyl; wherein R 5 and R 6 are independently, halogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; and p and q are independently integers from 0 to 4; with the proviso that when: (a) A is C—R 4 , where R 4 is hydrogen or C 1-6 alkyl; R 2 is not: (i) hydrogen or (ii) C 1-6 alkyl; wherein R 7 is halogen C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; and wherein R 8 is C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; R 2 is selected from the group consisting of: (i) hydrogen; (ii) C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; and (iii) benzyl, optionally substituted with: halogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl or C 1-6 alkyloxyalkyl; R 3 is selected from the group consisting of hydrogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl and C 1-6 alkyloxyalkyl; and is present only when A is C═O.