Patent ID: 6998236

Claim:
A method for detecting interaction between a test moiety and a plurality of target moieties, which method comprises: a) providing an integrated microarray device, which device comprises a substrate comprising a plurality of distinct microlocations and a plurality of microarray chips, wherein the number of said microlocations equals to or is more than the number of said microarray chips, and a plurality of target moieties attached to said microarray chips, and wherein the microlocations are in a well format comprising a plurality of wells wherein all of the wells are defined by inside and outside walls connected by thin girders wherein the thin girders and inside and outside walls of the wells form a space to contain an inert gas and thermally insulate adjacent wells from each other; b) contacting a test moiety with said plurality of target moieties provided in step a); and c) detecting interaction between said test moiety and said plurality of target moieties.