Patent ID: 7939263

Claim:
A method of classifying a solid tumor breast cancer comprising: (a) determining mRNA expression levels for genes: CTNNA1, ARMCX3, GLUL, RB1, CAV1, CAV2, IGFBP3, S100A2, MET, CDKN2A, and MFHAS1 from a solid tumor breast cancer sample; (b) comparing the determined mRNA expression levels of the genes in (a) to a pre-determined high risk expression profile, wherein the expression levels of CTNNA1, ARMCX3, GLUL, and RB1 are low or undetectable in the pre-determined high risk expression profile compared to expression in normal breast tissue and the expression levels of CAV1, CAV2, IGFBP3, S100A2, MET, CDKN2A, and MFHAS1 are elevated in the pre-determined high risk expression profile compared to expression in normal breast tissue; and, (c) classifying the cancer sample as high risk for a poor prognosis if the comparison in (b) is positively correlated or low risk for a poor prognosis if the comparison in (b) is negatively correlated.