Patent ID: 7879360

Claim:
A composition comprising: (a) particles of at least one active agent having an effective average particle size of less than about 2000 nm; and (b) at least one water soluble peptide surface stabilizer adsorbed on the surface of the active agent, wherein the peptide surface stabilizer is poly(Lysine, Tryptophan) 4:1 hydrobromide wherein: (a) the active agent is present in an amount selected from the group consisting of from about 99.5% to about 0.001%, from about 95% to about 0.1%, and from about 90% to about 0.5%, by weight, based on the total combined dry weight of the active agent and at least one peptide surface stabilizer, not including other excipients; or (b) the at least one surface stabilizer is present in an amount selected from the group consisting of from about 0.5% to about 99.999% by weight, from about 5.0% to about 99.9% by weight, and from about 10% to about 99.5% by weight, based on the total combined dry weight of the active agent and at least one peptide surface stabilizer, not including other excipients, and wherein the composition does not produce significantly different absorption levels when administered under fed as compared to fasting conditions.