Patent ID: 7371744

Claim:
A method of treatment of a fungal infection due to Candida albicans , Gram negative bacterial infection due to E. coli or P. aeruginosa , or Gram positive bacterial infection due to S. aureus or methicillin resistant S. aureus , the method comprising administering to a subject having an area infected with Candida albicans, E. coli, P. aeruginosa, S. aureus or methicillin resistant S. aureus , by systemic administration or by local application to said infected area, a therapeutically effective amount of a compound selected from the group consisting of: [3,7-(tetra-n-propylamino)-phenothiazin-5-ium] P X P− , [3,7-(tetra-n-butylamino)-phenothiazin-5-ium] P X P− , [3,7-(tetra-n-pentylamino)-phenothiazin-5-ium] P X P− , [3,7-(tetra-iso-pentylamino)-phenothiazin-5-ium] P X P− , [3-(N,N-di-n-butylamino)-7-(N,N-di-n-propylamino)-phenothiazin-5-ium] P X P− , [3-(N,N-di-n-hexylamino)-7-(N,N-di-n-propylamino)-phenothiazin-5-ium] P X P− , [3-(2-ethylpiperidino)-7-(N,N-di-n-pentylamino)-phenothiazin-5-ium] P X P− , [3-(2-methylpyrrolidino)-7-(N,N-di-n-pentylamino)-phenothiazin-5-ium] P X P− , [3,7-(N,N-tetra-iso-butylamino)-phenothiazin-5-ium] P X P− , [3-(N,N-di-n-butylamino)-7-(N,N-di-iso-pentylamino)-phenothiazin-5-ium] P X P− , [3-(N,N-diethylamino)-7-(N,N-di-n-propylamino)-phenothiazin-5-ium] P X P− , [3-(N,N-di-n-pentylamino)-7-(N,N-di-n-propylamino)-phenothiazin-5-ium] P X P− , [3-(N,N-di-n-butylamino)-7-(N,N-di-n-pentylamino)-phenothiazin-5-ium] P X P− , and [3-((N-ethyl-N-cyclohexyl) amino)-7((-N-ethyl)-N-cyclohexyl) amino-phenothiazin-5-ium] P X P− , wherein X P− is a counteranion and P is 1, 2 or 3, and exposing said infected area to light to render active said compound and thereby effecting said treatment of said fungal infection, said Gram negative bacterial infection or said Gram positive bacterial infection.