Patent ID: 7858794

Claim:
A tetrahydroquinoline derivative according to Formula 1, or a pharmaceutically acceptable salt thereof, wherein R 1 and R 2 are H or Me R 3 is H, hydroxy, (1-4C)alkoxy, R 4 is H, OH, or (1-4C)alkoxy, R 5 is OH, (1-4C)alkoxy or R 7 , with the proviso that if R 4 is H, R 5 is not OH or (1-4C)alkoxy R 6 is (2-5C)heteroaryl, (6C)aryl, (3-8C)cycloalkyl, or (1-6C)alkyl, wherein the (2-5C)heteroaryl and the (6C)aryl are optionally substituted with one or more substituents selected from hydroxyl, amino, halogen, phenyl, (1-4C)alkyl, (1-4C)alkoxy, or (1-4C)(di)alkylamino, R 7 is amino, (di)(1-4C)alkylamino, (2-5C)heteroarylcarbonylamino, (2-5C)heteroarylcarbonyloxy, R 8 -(2-4C)alkoxy, R 9 -methylamino or R 9 -methoxy R 8 is amino, (di)(1-4C)alkylamino, (2-6C)heterocycloalkyl, (2-6C)heterocycloalkylcarbonylamino, or (1-4C)alkoxycarbonylamino and R 9 is aminocarbonyl, (di)(1-4C)alkylaminocarbonyl, (2-5C)heteroaryl, optionally substituted with one or more (1-4C)alkyl substituents, or (6C)aryl.