Patent ID: 8546345

Claim:
A method for inhibiting expression of human vascular endothelial growth factor (VEGF) comprising: administering to a subject an effective amount of a pharmaceutical composition comprising a double-stranded short interfering ribonucleic acid (siRNA) having a sense RNA strand and an antisense RNA strand, wherein the sense and the antisense RNA strands form an RNA duplex, and wherein the sense RNA strand comprises a nucleotide sequence identical to a target sequence in human vascular endothelial growth factor (VEGF) mRNA, wherein the nucleotide sequence identical to a target sequence consists of a sequence selected from the group consisting of: SEQ ID NO. 13, 19, 20, 47, 48, 50, 51, 52, 56, 16, 23, 28, 29, 34, 57, 66, 71, 75, 84, and 88.