Patent ID: 8183292

Claim:
A compound comprising a chiral cyclic 2-amino-6,6-dimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid derivative of general formula (I) wherein R is C 1-4 Alk; X is —COOH, —CONH 2 , —CONH(C 1-4 Alk), —CON(C 1-4 Alk) 2 , —COO(C 1-4 Alk), —COPhe-O—(C 1-4 Alk) or —CH 2 OH; Y is —NH 2 , —NHBoc, —NHFmoc, —NH(C 1-4 Alk), —N(C 1-4 Alk) 2 , —NHCH 2 Ph, or Ar—NH—C(═X 0 )—N(R 0 )—, wherein Ar is a phenyl group substituted by one or two C 1-4 alkoxy group(s) or by one halogen, X 0 is O or S, and R 0 is hydrogen or benzyl; and X+Y is —CONH— or —CON(Boc)-; with the proviso that if X is —COOH, then Y is not —NH 2 and their salts formed with pharmaceutically acceptable acids or bases.