Patent ID: 7432368

Claim:
A nucleoside derivatives having a photolabile protecting groups of the formula (I) wherein R 1 =H, halogen, NO 2 , CN, OCH 3 , an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms, or an optionally substituted aryl residue or aliphatic acyl residue having 2 to 5 atoms, R 2 to R 7 =H, NO 2 , CN, OCH 3 , a branched or unbranched alkyl, alkoxy or alkoxyalkyl residue having 1 to 5 C atoms or an optionally substituted aryl residue or an aliphatic acyl residue having 2 to 5 atoms, X is C═O or C═S, Y=S, O, NR′, C(R′) 2 , wherein R′ is H, or a branched or unbranched alkyl residue having 1 to 5 C atoms or an optionally substituted aryl residue, Z=SO 2 , OCO, OCS, SCS, CO or CS, n=0, 1, 2 or 3 with the proviso that when n=0, Z is CO, CS, or SO 2 , N is wherein P=H or a protecting group common in nucleotide chemistry or a common reactive group for the production of oligonucleotides, B=adenine, cytosine, guanine, thymine, uracil, 2,6-diaminopurine-9-yl, 5-methylcytosinyl-1-yl, 5-amino-4-imidazolecarboxylic acid-1-yl or 5-amino-4-imidazolecarboxylic acid amide-3-yl, wherein when B=adenine, cytosine or guanine having a primary amino function it optionally has a temporary or permanent protecting group thereon, and when B=thymine or uracil, the O 4 position optionally has a permanent protecting group, R 8 =H, OH, halogen, OR′ or SR′, wherein R′ is as defined above, or an aliphatic acyl residue having 2 to 5 c atoms or a protecting group common in nucleotide chemistry.