Patent ID: 8026275

Claim:
A method of treating or ischemic injury in a human, wherein the method comprises administering to the human an amount of a 2,6-diisopropyl phenol analog selected from the group consisting of: (4-fluorophenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (4-(trifluoromethyl)phenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (4-3,5diisopropylphenyl(4-nitrophenyl)methanone, (3-fluoro-4-(trifluoromethyl)phenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (3-(trifluoromethyl)phenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (3-fluoro-5-(trifluoromethyl) phenyl)-4-hydroxy-3,5-diisopropylphenyl)methanone, (4-hydroxy-3,5-diisopropylphenyl)naphthalene-2-yl)methanone, (3,5-bis(trifluoromethyl)phenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (4-tert-butylphenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (4-hydroxy-3,5-diisopropylphenyl)-(4-isobutylphenyl)methanone, (4-hydroxy-3,5-diisopropylphenyl)-(4-iodophenyl)methanone, (4-hydroxy-3,5-diisopropylphenyl)-(4-methoxyphenyl)methanone, (4-cyanophenyl)-4-hydroxy-3,5-diisopropylphenyl)methanone, (6-(trifluoromethyl)pyridin-3-yl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (4-bromophenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, (4-hydroxy-3,5-diisopropylphenyl)-(4-propylphenyl)methanone, (4-chlorophenyl)-(4-hydroxy-3,5-diisopropylphenyl)methanone, 4-((4-(trifluoromethyl)phenyl)-(methoxyimino)methyl)-2,6-diisopropylphenyl, 4-(4-(trifluoromethyl)benzyl)-2,6-diisopropylphenyl, 4-((4-(trifluoromethyl)phenyl)-(hydroxy)methyl)-2,6-diisopropylphenyl, 4-hydroxy-3,5-diisopropylphenyl)-(4-(methylsulfonyl)phenyl)methanone, and combinations thereof.