Patent ID: 8568993

Claim:
A method for detecting the presence, absence, progression, regression, or extent of a disease or disorder in a subject, comprising: a) obtaining two or more sample glycopeptides or glycoproteins from the subject; b) obtaining two or more reference glycopeptides or glycoproteins; c) comparing the sample glycopeptides or glycoproteins with the reference glycopeptides or glycoproteins using mass spectrometry; and d) detecting a difference in a glycosylation state between the sample glycopeptides or glycoproteins and the reference glycopeptides or glycoproteins; wherein a difference in the glycosylation state between the sample glycopeptides or glycoproteins and the reference glycopeptides or glycoproteins is indicative of the presence, absence, progression, regression, or extent of the disease or disorder.