Patent ID: 7463921

Claim:
A method for analyzing an effect of a pharmacological agent on an electrocardiogram (ECG) signal, comprising: obtaining a first ECG signal having at least one beat, the beat having a first repolarization interval represented by a portion of the first ECG signal from a first T-wave starting point to a first T-wave ending point; quantifying an area under the first ECG signal during the first repolarization interval; quantifying a first time to reach at least one percentage of the area under the first ECG signal during the first repolarization interval; administering the pharmacological agent; after administering the pharmacological agent, obtaining a second ECG signal having at least one beat, the beat having a second repolarization interval represented by a portion of the second ECG signal from a second T-wave starting point to a second T-wave ending point; quantifying an area under the second ECG signal during the second repolarization interval; quantifying a second time to reach the at least one percentage of the area under the second ECG signal during the second repolarization interval; detecting an altered ventricular repolarization based on the quantified first and second times.