Patent ID: 7994159

Claim:
A method for treating a cancer that express c-kit in a patient, comprising: a) determining if the patient's cancer expresses c-Kit kinase or a mutant c-Kit kinase; and b) if the cancer is determined to express c-Kit kinase or a mutant c-Kit kinase, administering to the patient a pharmacologically effective dose to inhibit c-Kit activity of said cKit kinase or mutant c-Kit kinase of a compound selected from the group consisting of: 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; 4-(3-chloro-4-(ethylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide, N6-methoxy-4-(3-chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxamide; and N6-methoxy-4-(3-chloro-4-(((ethylamino)carbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxamide, or a pharmaceutically acceptable salt thereof.