Patent ID: 7419978

Claim:
A compound having the formula (I) a pharmaceutically-acceptable salt thereof, or an enantiomer thereof, or a diastereomer thereof, wherein: K is nitrogen; Z is selected from —NHR 11 , —C(═O)NR 11 R 12 , —NR 11 C(O) 2 R 12 , —NR 11 C(═O)R 13 , —NR 11 C(═O)NR 12 R 13 , —NR 11 SO 2 R 14 , —SO 2 NR 12 , —C(═O)R 12 , —OC(═O)R 15 , —C(═O)NR 11 C(═O)R 13 , —C(═O)NR 11 C(═O)NR 12 R 13 , and optionally-substituted heteroaryl; R 5 is hydrogen or C 1-4 alkyl; R 6a and R 6b are each independently selected from the group consisting of hydrogen, C 1-4 alkyl, hydroxy, methoxy, halogen, cyano, amino, —NH(C 1-4 alkyl), —N(C 1-4 alkyl) 2 , —CF 3 , —OCF 3 , and C 1-4 alkyl substituted with one or two of hydroxy, methoxy, halogen, cyano, amino, —NH(C 1-4 alkyl), —N(C 1-4 alkyl) 2 —CF 3 , and/or —OCF 3 ; R is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, hydroxy, alkoxy, halogen, cyano, amino, alkylamino, haloalkoxy, cycloalkyl, aryl, heterocyclo, and heteroaryl; R 1 and R 2 are taken together with the nitrogen to which R 1 is attached to form a ring fused to ring D and the ring fused to ring D is selected from the group consisting of: R 3 is selected from the group consisting hydrogen, methyl, perfluoromethyl, methoxy, halogen, cyano, NH 2 , or NH(CH 3 ); R 9 is selected from hydrogen, alkyl, substituted alkyl, halogen, cyano, aryl, heteroaryl, —SR 10 , and —S(O) 2 R 10 , wherein R 10 is alkyl or substituted alkyl; R 11 is hydrogen, alkyl, or substituted alkyl; R 12 , R 13 and R 14 are independently selected from hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, hydroxy, alkoxy, aryl, cycloalkyl, heteroaryl, and heterocyclo, except R 14 is not hydrogen; and R 15 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, aryl, cycloalkyl, heterocyclo, and heteroaryl.