Patent ID: 7706875

Claim:
A method of treating a patient undergoing pharmacotherapy with a selected drug for treatment of a medical disorder, the method comprising: administering the selected drug to said patient at a first time point to treat said medical disorder; and applying a first electrical signal to a vagus nerve of the patient at a second time point, wherein said first electrical signal is selected so as to modulate at least one pharmacologic and/or pharmacokinetic property of the selected drug in the body of the patient, wherein said at least one property is selected from the group consisting of the rate of intestinal absorption of said drug or a biologically active metabolite thereof, plasma binding of said drug, solubility of said drug in a body fluid, volume of distribution of said drug, and clearance of said drug, and wherein said second time point is selected from the group consisting of a selected time before said first time point, a selected time after said first time point, and a selected time in the patient's circadian rhythm after said first time point.