Patent ID: 7163954

Claim:
A compound of the formula: or a pharmaceutically acceptable salt or ester form thereof, wherein: R, R 1 , R 2 , and R 3 are, independently, hydrogen, C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl, —CH 2 —(C 3 –C 6 cycloalkyl), C 1 –C 6 alkanoyl, halo, hydroxy, aryl, heteroaryl, C 1 –C 6 perfluoroalkyl, C 1 –C 6 alkoxy, amino, —NH(C 1 –C 6 alkyl), —N(C 1 –C 6 alkyl) 2 , or C 1 –C 6 perfluoroalkoxy; R 4 is hydrogen, C 1 –C 6 alkyl, perfluoroalkyl, aryl, heteroaryl, alkenyl, —CH 2 R 5 , —CH(OH)R 5 , —C(═O)R 5 , —CH(SH)R 5 , —C(═S)R 5 or —(CH 2 ) m —C 3 –C 6 cycloalkyl; n is an integer from 0 to 6; m is an integer from 0 to 6; R 5 is hydrogen, C 1 –C 8 alkyl, perfluoroalkyl, aryl, heteroaryl, alkenyl, C 3 –C 6 cycloalkyl, arylalkyl, or —(CH 2 ) p —C 3 –C 6 cycloalkyl; p is an integer from 0 to 6; R 6 is hydrogen, C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl, —CH 2 -(C 3 –C 6 cycloalkyl), arylalkyl, alkylaryl, aryl, or heteroaryl; and A is COOH, or an acid mimic or a pharmaceutically acceptable salt thereof.