Patent ID: 7041310

Claim:
A pharmaceutical preparation for the treatment of gynecological diseases which comprises a therapeutic drug for the intrauterine, intravaginal or intrapelvic administration, or for the administration into the ovarian endometrioma and a biodegradable polymer comprising chemically modified hyaluronic acid or a salt thereof, wherein the chemically modified hyaluronic acid or a salt thereof is prepared by O-acylating a complex of hyaluronic acid or a salt thereof and a quaternary ammonium salt in a non-aqueous solvent and contains a decreased amount of a pyrogen and/or an antigenic substance, said amount has been decreased by the O-acylating in the non-aqueous solvent to the extent that the amount of the pyrogen is not more than 0.05 endotoxin unit (EU)/mg, and wherein the drug is supported by the biodegradable polymer as a carrier.