Patent ID: 7858560

Claim:
A collection of capture compounds, comprising a plurality of different capture compounds, wherein: each and every capture compound in the collection has the formula: the collection includes at least ten different capture compounds; X is a reactivity function that covalently binds to amino acid side chains of proteins; Y, the selectivity function, interacts non-covalently with proteins and modulates one or more of the affinity, steric properties and electronic properties of the capture compound thereby increasing selectivity of the binding by X to the amino acid side chains of the proteins, whereby X covalently binds to fewer side chains of the proteins when Y is present than in its absence; Q permits separation or immobilization of capture compounds in the collection and is selected from among biotin, 6-His, an oligonucleotide, BODIPY, an antibody, an immunotoxin conjugate, an adhesive peptide, a lectins, liposomes, protein nucleic acid (PNA) and an activated dextran; Z is a trityl derivative for presenting functional moieties X, Y and Q; and Z has the formula: any two of moieties Q, X and Y are attached to the phenyl rings, and the remaining moiety is attached to the central carbon atom.