Patent ID: 7611621

Claim:
A method of correcting the oxygen effect on oxidase-based analyte sensors comprising: determining an oxygen concentration of a fluid sample using an oxygen sensor comprising a working electrode, a reference electrode and a reagent matrix disposed on at least said working electrode wherein said reagent matrix contains a reduced form of a redox mediator, an oxidase and a peroxidase and wherein said oxygen sensor has a known correlation between oxygen concentration and analyte concentration expressed as a function of the response of said oxygen sensor to both oxygen and an analyte wherein said analyte is a substrate of said oxidase; using an oxidased-based analyte sensor wherein the correlation between oxygen concentration and oxygen effect on said oxidase-based analyte sensor is known and wherein an oxidase in said oxidased-based sensor is a substrate of said oxidase in said oxygen sensor; determining an analyte concentration of said fluid sample using said oxidase-based analyte sensor; and calculating a corrected analyte concentration in said fluid sample using said determined oxygen concentration.