Patent ID: 8222419

Claim:
An oxepin derivative, and salt thereof that are pharmaceutically acceptable, wherein the oxepin derivative is represented by the following general formula (I): wherein R 1 is a hydrogen, a formyl, a carbonitrile, a tetrazolyl, a carboxyl, a carboxyalkyl, a hydroxyalkylaminocarbonyl, an alkoxycarbonylalkylaminocarbonyl, a hydroxyalkenyl, a carboxyalkenyl, an alkoxycarbonylalkenyl, a ureido, an alkylcarbonylamino, or an aminoalkyl which may be substituted by one or two substituents selected from the following (a) to (e): (a) an alkylcarbonyl; (b) an alkoxycarbonyl; (c) a carboxyalkylcarbonyl; (d) an alkoxycarbonylalkylcarbonyl; and (e) a benzoyl; R 2 is a hydrogen, and R 3 is a substituent at 8-position or 9-position of the dibenzoxepin backbone, and stands for a hydrogen, a carboxyl, an alkoxycarbonyl, or a hydroxyalkylaminocarbonyl, wherein one of R 1 , and R 3 stands for the substituent as defined above other than the hydrogen, and the remaining one stands for a hydrogen.