Patent ID: 8501683

Claim:
A cycloundecadepsipeptide compound of Formula (I) in which: AXX 1 is MeBmt, 4-fluoro-MeBmt, dihydro-MeBmt, 8-hydroxy-MeBmt, or O-acetyl-MeBmt; AXX 2 is Abu, Val, Thr, Thr(OMe), Thr(OAc), Thr(OCOCH 2 CH 2 CH 2 OH), Nva, or 5-hydroxy-Nva; AXX 3 is D-MeAla, D-3-fluoro-MeAla, D-MeSer, D-MeSer(OAc), D-MeSer(OCH 2 CH 20 H), D-MeSer(OCH 2 CH 2 NEt 2 ), or D-MeAsp(OMe); AXX 4 is MeIle, MeMet, MeVal, MeThr, MeThr(OAc), MeAla, EtVal, EtIle, EtPhe, EtTyr, EtThr(OAc), MeThr(OAc), MeTyr, MeTyr(OAc), MeTyr(OMe), MePhe, or MeMet(Ox), wherein the sulphur atom of methionine is sulphoxyde or sulphone; AXX 5 is Leu, Val, or Ile; AXX 6 is MeAla, Sar, or MeLeu; and AXX 7 is Gly or Ala.