Patent ID: 7977322

Claim:
A compound having formula IIIB: wherein: X 9 is CH 2 or CF 2 ; m is 0 to 4; Ht 1 is a 5-membered heteroaromatic ring containing 1-4 heteroatoms selected from O, S, N, or NH; x, q, and z is independently 0-5; X—R x is H or unsubstituted alkyl; Z—R z is halo, C 1 -C 8 aliphatic, OR 6 , SO 2 R 6 , CF 3 , or two occurrences of Z—R z taken together with the atom(s) to which they are bound form a ring having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; L is CHR L ; R L is —OR′ or —N(R′) 2 ; Ar is phenyl or a six-membered heteroaromatic ring; R′ is independently selected from hydrogen or an optionally substituted group selected from a C 1- C 8 aliphatic group, or a 3-8-membered saturated, partially unsaturated, or fully unsaturated monocyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or two occurrences of R′ are taken together with the atom(s) to which they are bound to form an optionally substituted 3-12 membered saturated, partially unsaturated, or fully unsaturated monocyclic or bicyclic ring having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; and R 6 is H or aliphatic.