Patent ID: 7842815

Claim:
A compound of formula 1: or a pharmaceutically acceptable salt thereof; wherein independently for each occurrence; n is 0, 1, 2, 3, or 4; R 1 independently for each occurrence is H, alkyl, alkenyl, alkynyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, heteroaralky, halide, hydroxyl, alkoxyl, aryloxy, acyloxy, amino, alkylamino, arylamino, acylamino, aralkylamino, nitro, acylthio, carboxamide, carboxyl, nitrile, —COR 5 , —CO 2 R 5 , —N(R 5 )CO 2 R 6 , —OC(O)N(R 5 )(R 6 ), —N(R 5 )SO 2 R 6 , or —N(R 5 )C(O)N(R 5 )(R 6 ); R 2 and R 3 independently for each occurrence are H, alkyl, alkenyl, alkynyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, heteroaralkyl, or —[C(R 5 )(R 6 )] p —R 4 ; or has the formula 1a wherein m is 0, 1, 2, 3, 4, or 5; R 7 for each occurrence independently is H, alkyl, aryl, alkenyl, halide, hydroxyl, alkoxyl, alkenyloxy, aryloxy, acyloxy, amino, alkylamino, arylamino, acylamino, aralkylamino, nitro, acylthio, carboxamide, carboxyl, nitrile, —OSO 3 R 5 , —SO 2 R 5 , —S(O)R 5 , —SR 5 , —PO 2 OR 5 , —OPO 2 OR 5 , —COR 5 , —CO 2 R 5 , —OCH 2 CO 2 R 5 , or —OCH 2 C(O)N(R 5 )(R 6 ); or two occurrences of R 7 taken together may form a monocyclic ring between 5-8 ring atoms, of which, one, two, or three atoms are independently S, O, or N; R 4 is halide, hydroxyl, alkoxyl, aryloxy, acyloxy, amino, alkylamino, arylamino, acylamino, aralkylamino, nitro, acylthio, carboxamide, carboxyl, nitrile, —OSO 3 R 5 , —SO 2 R 5 , —S(O)R 5 , —PO 2 OR 5 , —OPO 2 OR 5 , —COR 5 , —CO 2 R 5 , —N(R 5 )CO 2 R 6 , —OC(O)N(R 5 )(R 6 ), —N(R 5 )SO 2 R 6 , or —N(R 5 )C(O)N(R 5 )(R 6 ); and each of R 5 and R 6 independently for each occurrence is H, alkyl, alkenyl, alkynyl, aryl, aralkyl, cycloalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroaralkyl; or R 5 and R 6 taken together form a monocyclic ring with 4-8 ring atoms, of which one, two, or three ring atoms are independently S, O, or N.