Patent ID: 7105526

Claim:
A compound of the formula (I), wherein B and D are methine, said methine being optionally substituted by a substituent selected from the group consisting of halogen, cyano, lower alkyl, halo-lower alkyl, hydroxy, lower alkoxy, halo-lower alkoxy, lower alkoxycarbonyl, lower alkylsulfonyl, lower alkylsulfonyloxy, —N(R 1 )R 2 and —Q 1 —Ar 1 , and A and C are nitrogen; Ar 1 is aryl or heteroaryl, any of which is optionally substituted by a substituent selected from the group consisting of halogen, nitro, hydroxy, lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, cyclo-lower alkyl, lower alkenyl, lower alkoxy, halo-lower alkoxy, lower alkylthio, lower alkylsulfonyl, carboxyl, lower alkanoyl, lower alkoxycarbonyl, lower alkanoylamino and —Q 2 —Ar 2 ; Ar 2 is aryl or heteroaryl, any of which is optionally substituted by a substituent selected from the group consisting of halogen, cyano, lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, hydroxy, lower alkoxy, halo-lower alkoxy, lower alkylamino, di-lower alkylamino, lower alkanoyl and aryl; E is methine or hydroxy substituted methine; n is 0; Q 1 and Q 2 are independently a single bond, oxygen, carbonyl or —N(R 3 )—; R 1 and R 2 are independently hydrogen or lower alkyl, or R 1 and R 2, taken together, form lower alkylene which may be intervened by oxygen, sulfur or imino; R 3 is hydrogen or lower alkyl; T, V and W are methine, said methine being optionally substituted by a substituent selected from the group consisting of halogen, lower alkyl, halo-lower alkyl, hydroxy, lower alkoxy and halo-lower alkoxy, and U is nitrogen; X is —CO—; Y is —O—, and a salt, ester or N-oxide derivative thereof.