Patent ID: 7462639

Claim:
A compound according to formula I, wherein: R 1 is selected from the group consisting of hydrogen and alkyl; R 2 is alkyl; R 3 is alkyl; Z is selected from the group consisting of: —C(O)—, —C(O)NR 7 —, —C(O)O—, and —S(O) 2 —; n is 0 or 1; R 7 is hydrogen or alkyl; R 4 is selected from the group consisting of: hydrogen; alkyl, which is optionally substituted one or more times by halogen, alkoxy, or dialkylamino; aryl-V—, wherein the aryl is optionally substituted one or more times by halogen, cyano 2,4-dioxa-pentan-1,5-diyl, 2,5-dioxa-hexan-1,6-diyl, hydroxy, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, or halogenated (C 1 -C 4 )alkyl; heteroaryl-V—, wherein the heteroaryl is optionally substituted one or more times by alkyl; cycloalkyl-V—; and heterocyclyl-V—; with the proviso that R 4 is not hydrogen, if n is 1 and Z is —C(O)O—; V is selected from the group consisting of: a single bond, alkylene, —O-alkylene, cycloalkylene, and alkenylene; R 5 is selected from the group consisting of hydrogen and alkyl; and X is a single bond; or a pharmaceutically-acceptable salt or ester thereof.