Patent ID: 8871712

Claim:
A non liquid-crystalline formulation precursor having a viscosity of between 1-1000 mPas at 20° C. for the in vivo generation of a liquid crystalline lipid composition for the controlled release of at least one somatostatin analogue following parenteral administration, said non liquid-crystalline formulation precursor comprising a mixture of: a) 27-67.5 wt. % of at least one diacyl glycerol; b) 22.5-63 wt. % of at least one phosphatidyl choline; c) at least one oxygen containing organic solvent; and d) at least one somatostatin analogue, wherein the at least one somatostatin analogue having somatostatin activity is a cyclic peptide of 14 or fewer amino acids having at least one intra-molecular crosslink and a type-2 β turn; and wherein the formulation precursor forms at least one liquid crystalline phase structure upon contact with an aqueous fluid.