Patent ID: 8207203

Claim:
An isoxazole compound represented by formula (I) where in the formula, R 1 and R 2 each independently stands for hydrogen, halogen, lower alkyl, lower alkoxy, amino, lower alkylamino, di-lower alkyl-amino, phenyl-lower alkylamino, acylamino, lower alkylthio or lower alkylsulfinyl, R 3 stands for a group represented by the following formula (A) wherein X 1 , X 2 and X 3 each independently stands for hydrogen, halogen, lower alkyl, lower haloalkyl, lower alkoxy, lower haloalkoxy, hydroxyl, lower alkanoyl, lower haloalkanoyl or phenyl, R 4 stands for hydrogen or lower alkyl, R 5 stands for phenyl, which may be optionally substituted with 1-3 substituents selected from halogen, lower alkyl, lower haloalkyl, lower alkoxy, hydroxyl, lower alkanoyl, lower haloalkanoyl, lower alkylthiocarbonyl, lower haloalkylthio-carbonyl, amino, lower alkylamino, di-lower alkylamino and nitro, Y stands for —(CH 2 ) n —, —CO—, —CH(CH 3 )—, —C(CH 3 ) 2 —, —O—, —NH— or wherein n is an integer of 1 -3, with the proviso that, where both of R 1 and R 2 stand for hydrogen and two of X 1 , X 2 and X 3 stand for hydrogen, the remaining one of X 1 , X 2 and X 3 is a group other than hydrogen atom or halogen atom, or a pharmaceutically acceptable salt thereof.