Patent ID: 8012974

Claim:
A compound of Formula I wherein: R 1 is lower alkyl, cycloalkyl, cycloalkyl lower alkyl, phenyl, phenyl lower alkyl, heterocycloalkyl, heterocycloalkyl lower alkyl, heteroaryl, heteroaryl lower alkyl, or spirocycloalkyl, each optionally substituted with one or more R 1′ ; R 1′ is halogen, lower alkyl, hydroxy, lower hydroxyalkyl, lower alkoxy, lower haloalkyl, amino, —C(═O)N(R 1a ) 2 , —C(═O)O(R 1a ), —C(═O)(R 1a ), —S(═O) 2 (R 1a ), oxo, cyano, sulfonamido, cycloalkyl, or spirocycloalkyl; each R 1a is H or R 1b ; R 1b is lower alkyl, lower haloalkyl, lower alkoxy, hydroxy lower alkyl, cyano lower alkyl, cycloalkyl, cycloalkyl lower alkyl, spirocycloalkyl, spirocycloalkyl lower alkyl, heterocycloalkyl, heterocycloalkyl lower alkyl, spiroheterocycloalkyl, or spiroheterocycloalkyl lower alkyl, each optionally substituted with one or more R 1b′ ; R 1b′ is halogen, hydroxy, lower alkyl, lower alkoxy, lower haloalkyl, or hydroxy lower alkyl; R 2 is H or lower alkyl; and R 3 , R 4 , and R 5 are independently selected from the group consisting of H, lower alkyl, halogen, hydroxy, lower hydroxyalkyl, lower alkoxy, and lower haloalkyl; or a pharmaceutically acceptable salt thereof.