Patent ID: 8394785

Claim:
A method for the treatment and/or amelioration of urticaria comprising administration of a pharmaceutically active dose of a compound to a subject in need of such a treatment and/or amelioration wherein the compound has the following formula I wherein R 1 is a C 4-13 hydrocarbon group comprising a quarternary nitrogen atom; X is O or a direct bond; R 2 is a C 10-20 hydrocarbon group, wherein one or more hydrogens are optionally replaced by fluorine and wherein one or more CH 2 groups are optionally replaced by oxygen, or a group of the following formula II wherein Y is O, O(CO), S or S(CO); R 3 is OH, C 1-4 alkyl, O—C 1-3 alkyl, O(CO)NH—C 1-3 alkyl, O(CO)—C 1-6 alkyl, S(CO)—C 1-6 alkyl, O(CO)—C 2-3 alkenyl or CH 2 O—C 1-3 alkyl; R 3′ is H or C 1-4 alkyl; and R 4 is a C 10-20 hydrocarbon group, wherein one or more hydrogens are optionally replaced by fluorine.