Patent ID: 7265246

Claim:
A compound of the formula wherein Q, X, Y, and Z are independently selected from the group consisting of CR 1 and N, provided that no more than two of Q, X, Y, and Z are N and at least two of Q, X, Y, and Z are CH; or Y is CH, Z is CH, and the moiety “Q═X” represents “S” to form a thiophene ring; R 1 is independently at each occurrence selected from the group consisting of hydrogen, halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; R 2 is selected from the group consisting of halogen; C 1 -C 4 alkoxy; C 1 -C 4 alkyl; C 3 -C 8 cycloalkyl; cyano; trifluoromethyl; pyridinyl optionally substituted with one to two substituents independently selected from the group consisting of halogen, C 1 ,-C 4 alkoxy, and C 1 -C 4 alkyl; thienyl optionally substituted with one substituent selected from the group consisting of halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; phenyl optionally substituted with from one to three substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, C 1 -C 4 alkyl, trifluoromethyl, and cyano; and pyrrolyl optionally substituted with one to two substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; R 3a is a radical of the formula (Z′)-(Y′) q -(′) p - wherein: X′ is selected from the group consisting of C 1 -C 4 alkandiyl and Y′ is selected from the group consisting of O and S; and Z′ is selected from the group consisting of C 1 -C 4 alkyl; C 3 -C 8 cycloalkyl optionally substituted with one to three substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, C 1 -C 4 alkyl, trifluoromethyl, cyano, and nitro; phenyl optionally substituted with one to three substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, C 1 -C 4 alkyl, trifluoromethyl, cyano, and nitro; heteroaryl optionally substituted with one or two substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; and heterocycle optionally substituted with one or two substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; p is zero or one; q is zero or one; provided that when p is zero, q is zero; R 3b is selected from the group consisting of hydrogen, C 1 -C 4 alkyl, and benzyl; or R 3a and R 3b are taken together with the nitrogen with which they are attached to form a heterocycle optionally substituted with one or two substituents independently selected from the group consisting of halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; R 4 is selected from the group consisting of hydrogen, hydroxy, and fluoro; R 5 is selected from the group consisting of hydrogen, halogen, C 1 -C 4 alkoxy, and C 1 -C 4 alkyl; m is one or two; n is one or two; or pharmaceutically acceptable addition salts thereof.