Patent ID: 6987113

Claim:
A compound having the following chemical structure: wherein, A is selected from the group consisting of nitrogen, oxygen and sulfur and it is understood that when A is oxygen or sulfur, R 3 does not exist and there is no bond; B is selected from the group consisting of carbon and nitrogen and it is understood that when B is nitrogen, R 6 does not exist and there is no bond; D, E, F and G are selected from the group consisting of carbon and nitrogen such that either D and F are nitrogen and E and G are carbon, or E and G are nitrogen and D and F are carbon, it being understood that when D, E, F or G is nitrogen, R 7 , R 8 , R 9 and R 10 , respectively, do not exist and there is no bond; Z is selected from the group consisting of oxygen, sulfur and NR 11 wherein, R 11 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, hydroxy, alkoxy, aryloxy, —C(═O)—R″, —C(═O)O—R″, R″—C(═O)O—, —C(═O)NR 12 R 13 , —S(═O) 2 R″ and trihalomethanesulfonyl; R 1 is selected from the group consisting of hydrogen, and alkyl; R 2 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl and halogen; when A is nitrogen, R 3 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, hydroxy, alkoxy, aryloxy, —C(═O)—R″, —C(═O)O—R″, R″—C(═O)O—, —C(═O)NR 12 R 13 , —S(═O) 2 R″ and trihalomethanesulfonyl wherein, R″ is selected from the group consisting of hydrogen, alkyl, cycloalkyl and aryl; R 4 , R 5 R 6 , R 7 , R 8 , R 9 and R 10 are independently selected from the group consisting of hydrogen, alkyl, trihaloalkyl, cycloalkyl, alkenyl, alkynyl, aryl, hydroxy, alkoxy, aryloxy, —S(═O)—R″, —S(═O) 2 R″, —S(═O) 2 NR 12 R 13 , R 12 S(═O) 2 NR 13 —, trihalomethanesulfonyl, —C(═O)—R″, —C(═O)O—R″, R″—C(═O)O—, —C(═O)—NR 12 R 13 , R 12 C(═O)NR 13 —, cyano, nitro, halo, —OC(═O)NR 12 R 13 , R 12 OC(═O)NR 13 —, amino and —NR 12 R 13 ; wherein R 12 and R 13 are independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, —C(═O)—R″ and —S(═O) 2 R″; and R 4 and R 5 or R 5 and R 6 may combine to form a six-member cycloalkyl or aryl; and the physiologically acceptable salt thereof.