Patent ID: 7468375

Claim:
A compound of formula (I), wherein: R 1 is hydrogen, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, or C 1 -C 8 heteroalkyl, wherein said C 1 -C 8 alkyl, C 2 -C 8 alkenyl, or C 1 -C 8 heteroalkyl groups may be optionally substituted with at least one substituent independently selected from: halo, —OR 12a , —N(R 12a R 12b ), —C(O)N(R 12a ) 2 , —NR 12a C(O)N(R 12a R 12b ), —NR 12a C(O)R 12a , —NR 12a C(NR 12a )N(R 12a R 12b ), —SR 12a , —S(O)R 12a , —S(O) 2 R 12a , —S(O) 2 N(R 12a R 12b ) 2 , C 1 -C 8 alkyl, C 6 -C 14 aryl, C 3 -C 8 cycloalkyl, and C 2 -C 9 heteroaryl, wherein said C 1 -C 8 alkyl, C 6 -C 14 aryl, C 3 -C 8 cycloalkyl, and C 2 -C 9 heteroaryl groups are optionally substituted with at least one substituent independently selected from halo, —C(R 12a R 12b R 12c ), —OH, and C 1 -C 8 alkoxy; R 2 is hydrogen; R 3 is —(CR 8 R 9 ) t NR 10 R 11 or C 1 -C 8 heteroalkyl, wherein said C 1 -C 8 heteroalkyl is substituted with R 24 ; R 4 is hydrogen, halo, C 1 -C 8 alkyl, —OR 12a , —NR 12 R 12b , C 1 -C 8 heteroalkyl, C 2 -C 8 alkenyl, or C 2 -C 8 alkynyl, wherein said C 2 -C 8 alkenyl or C 2 -C 8 alkynyl are optionally substituted with at least one R 26 ; R 5 is hydrogen; R 6 is hydrogen, C 1 -C 8 alkyl, C 1 -C 8 heteroalkyl, or C 2 -C 8 alkenyl, wherein said C 2 -C 8 alkenyl is optionally substituted with at least one —OR 12a group; R 7 is hydrogen, C 1 -C 8 heteroalkyl, C 6 -C 14 aryl, C 2 -C 8 alkenyl, or C 1 -C 8 alkyl, wherein said C 1 -C 8 alkyl is optionally substituted with at least one C 3 -C 8 cycloalkyl or C 6 -C 14 aryl group; each R 8 and R 9 , which may be the same or different, are independently selected from hydrogen and C 1 -C 8 alkyl; R 10 and R 11 , together with the nitrogen atom to which they are attached, form a C 2 -C 9 cycloheteroalkyl group optionally substituted with at least one C 1 -C 8 alkyl; each R 12a , R 12b , and R 12c , which may be the same or different, is independently selected from hydrogen and C 1 -C 8 alkyl; R 24 is C 3 -C 8 cycloalkyl, C 2 -C 9 cycloheteroalkyl, or C 2 -C 9 heteroaryl, each of which is optionally substituted with at least one substituent independently selected from C 1 -C 8 alkyl, C 6 -C 14 aryl, C 2 -C 9 heteroaryl, —CF 3 , and —OR 12a ; each R 26 is independently selected from —OR 12a , halo, C 6 -C 14 aryl, C 2 -C 9 heteroaryl, C 1 -C 8 heteroalkyl, C 3 -C 8 cycloalkyl, C 2 -C 9 cycloheteroalkyl, and —C(R 12a R 12b R 12c ); and t is an integer from 1 to 3; or a pharmaceutically acceptable salt or solvate thereof.