Patent ID: 7022714

Claim:
A compound having the Formula I: or a pharmaceutically acceptable salt, or solvate thereof, wherein: R 1 is selected from the group consisting of: where Y is an optionally substituted C 2-6 alkylene, and R 3 and R 4 together with the nitrogen to which they are attached form a ring having 4 or 5 carbon atoms, which ring optionally contains 1 or 2 additional heteroatoms independently selected from oxygen and NR 5 , where R 5 is hydrogen or alkyl, or said ring is optionally substituted with an alkyl or aryl moiety; and (ii) piperidin-4-ylalkyl, optionally substituted by alkyl, aryl or aralkyl; R 2 is selected from the group consisting of: (i) optionally substituted phenoxyphenyl; (ii) optionally substituted benzyloxyphenyl; (iii) optionally substituted phenylthiophenyl; (iv) optionally substituted benzylthiophenyl; (v) optionally substituted phenylaminophenyl; (vi) optionally substituted benzylaminophenyl; wherein R 6 and R 7 are independently halogen, alkyl, alkoxy or haloalkyl; and p and q are integers from 0 to 4; wherein R 8 is hydrogen, halogen, alkyl or alkoxy; wherein R 9 is hydrogen or alkyl; and (x) naphthalyl; R 10 is selected from halogen, hydroxy, alkyl, alkoxy and alkoxyalkyl, wherein any alkyl moiety of R 10 can be optionally substituted by one or more of halogen or hydroxy; and n is an integer from 0 to 4, where when n is 0, R 10 is absent and the benzene ring of the benzimidazole compound has four hydrogen atoms attached thereto, and when R 10 is present, R 10 replaces one or more of the available hydrogen atoms on the benzene ring of the benzimidazole compound.