Patent ID: 7674586

Claim:
A method of identifying a modulator of a GluCl channel protein, comprising: (a) contacting a test compound in the presence and absence of a R. sanguineus GluCl channel protein selected from the group consisting of SEQ ID NO:2, SEQ ID NO;4, and SEQ ID NO:6; (b) measuring the effect of the test compound the presence and absence of the R. sanguineus GluCl channel protein of (a), wherein the effect that is measured is selected from the group consisting of: the expression of DNA encoding the R. sanguineus GluCl channel protein of (a), the expression of RNA encoding the R. sanguineus GluCl channel protein of (a), and a channel activity of the R. sanguineus GluCl channel protein of (a); and (c) comparing the effect of the test compound in the presence and absence of the R. sanguineus GluCl channel protein, wherein if the effect of the test compound measured in the presence of the R. sanguineus GluCl channel protein is greater than or less than the effect measured in the absence of the R. sanguineus GluCl channel protein, the test compound is a modulator of a GluCl channel protein.