Patent ID: 7780991

Claim:
A therapeutic composition in solid dose form comprising a bioactive material and a carbohydrate, wherein a) the bioactive material is a protein, b) the carbohydrate stabilizes the bioactive material in the presence of an organic solvent, c) the therapeutic composition comprises therapeutic particles which contain said protein homogeneously distributed in solid solution in said carbohydrate in a glassy state, d) the therapeutic composition is a powder having a particle size distribution suitable for pulmonary administration, e) the therapeutic particles containing said protein and said carbohydrate in the solid solution remain in the glassy state when stored at 60° C. for one month, f) the carbohydrate is selected from the group consisting of monosaccharides, disaccharides and sugar alcohols, and g) the therapeutic particles have a mean particle size of 0.5 to 5 μm.