Patent ID: 8465745

Claim:
A purified chimeric antigen for eliciting an immune response against Hepatitis C in a host, said chimeric antigen comprising: an immune response domain, wherein the immune response domain comprises at least one immunogenic portion of an HCV protein selected from the group consisting of a HCV E1 protein, a HCV E2 protein, a HCV E1-E2 protein, a HCV NS3 protein, a HCV NS4B protein, and a HCV NS5A protein, and a combination thereof, a target binding domain, wherein the target binding domain consists of a hinge region, at least a portion of a C H 1 region and a xenotypic Fc antibody fragment comprising at least part of a C H 2 and C H 3 domain, wherein the immune response domain and the target binding domain are linked by peptide linkage.