Patent ID: 8232289

Claim:
A compound of the formula: wherein R 1 is fluoro or chloro; R 2a and R 2b are each hydrogen or are each fluoro; R 3 is hydrogen, methyl, hydroxymethyl, or (C 1 -C 3 ) alkoxymethyl; R 4 is selected from the group consisting of fluoro, chloro, cyano, cyanomethyl, (C 1 -C 3 ) alkyl, cyclopropyl, hydroxymethyl, methoxy, cyclopropylmethoxy, aminocarbonylmethoxy, (C 1 -C 3 ) alkoxymethyl, cyclopropyloxymethyl, cyclopropylmethoxymethyl, 1-hydroxy-1-methylethyl, aminocarbonyloxymethyl, methylaminocarbonyloxymethyl, dimethylaminocarbonyloxymethyl, aminocarbonyl, aminocarbonylmethyl, —CH 2 —NR 5 R 6 , hydroxyimine, methoxyimine, morpholin-4-yl, morpholin-4-ylmethyl, Ar 1 , —CH 2 Ar 1 , tetrahydrofuran-2-yl, 3-oxomorpholin-4-ylmethyl, 2-oxopyrrolidin-1-ylmethyl, and 2-oxopiperidin-1-ylmethyl; R 5 is hydrogen, C 1 -C 3 alkyl, cyanomethyl, —C(O)CH 3 , or aminocarbonylmethyl; R 6 is hydrogen or methyl; and Ar 1 is a moiety selected from the group consisting of imidizol-1-yl, imidizol-2-yl, 2-methylimidizol-1-yl, pyrazol-1-yl, 1,2,3-triazol-1-yl; 1,2,3-triazol-2-yl; 1,2,4-triazol-1-yl, isoxazol-3-yl, oxazol-5-yl, and 3-methyl-1,2,4-oxadiazol-5-yl; or a pharmaceutically acceptable salt thereof.