Patent ID: 8198288

Claim:
A compound of formula (I): wherein A is selected from the group consisting of aryl and heteroaryl; D is selected from the group consisting of oxygen and sulphur; R 1 , R 2 , and R 3 are independently each selected from the group consisting of hydrogen, halogen, nitro, cyano, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, hydroxyl, C 1 -C 6 -alkoxy and C 2 -C 6 -alkenyloxy, wherein C 1 -C 6 -alkyl and C 1 -C 6 -alkoxy can be further substituted with one to three identical or different radicals selected from the group consisting of halogen, hydroxy and C 1 -C 4 -alkoxy; R 5 is hydrogen; R and R 4 each independently represent a radical of formula —[X] m —[Alk 1 ] p -[Q] n -[Alk 2 ] q —[X 1 ] k —Z wherein k, m, n, p and q are independently selected from 0 and 1; Alk 1 and Alk 2 each independently represent an optionally substituted C 1 -C 6 alkylene or C 2 -C 6 alkenylene radical which may optionally contain an ether (—O—), thioether (—S—) or amino (—NR A —) link; Q represents (i) a divalent radical selected from the group consisting of —O—, —S—, —S(═O)—, —S(═O) 2 —, —S + (R A )—, —N(R A )—, —N + (R A )(R B )—, —C(═O)—, —C(═O)O—, —OC(═O)—, —C(═O)NR A —, —NR A C(═O)—, —S(O 2 )NR A —, —NR A S(O 2 )—, —NR A C(═O)NR B —, —NR A C(═NR A )NR B —, —C(═NR D )NR E —, and —NR E C(═NR D )—, wherein R A , R B , R D and R E are independently, selected from the group consisting of hydrogen, C 1 -C 6 alkyl and C 3 -C 6 cycloalkyl, or R A and R B, or R D and R E taken together with the nitrogen to which they are attached form a monocyclic heterocyclic ring of 5 to 7 ring atoms which may contain a further heteroatom selected from N, O and S, or (ii) an optionally substituted divalent mono- or bicyclic carbocyclic or heterocyclic radical having 3-6 ring members; X represents a divalent radical selected from the group consisting of —(C═O)—, —S(O 2 )—, —C(═O)O—, —(C═O)NR A — and —S(O 2 )NR A —, wherein X 1 is selected from the group consisting of —O—, —S— and —NH; and Z is hydrogen or an optionally substituted mono- or bicyclic carbocyclic or heterocyclic radical having 3-6 ring members; or a pharmaceutically acceptable salt thereof.