Patent ID: 8703913

Claim:
An ADP binding molecule comprising a polypeptide, said polypeptide comprising an amino acid sequence corresponding to at least amino acids 11 to 310 of SEQ ID NO:1, wherein said polypeptide comprises: (a) a C287A substitution relative to SEQ ID NO: 1; (b) a cysteine residue for attachment of at least one reporter moiety wherein said polypeptide comprises a substitution or substitutions selected from the group consisting of: (i) I27C; (ii) D63C and K16C; and (iii) D63C and D224C; (c) substituting or substitutions selected from the group consisting of: (iv) T175N; (v) T174A and T175A; (vi) T174A and T175 and (vii) T175L; and (d) a residue selected from K or A at position 33.