Patent ID: 7767642

Claim:
A method of treating a cancer cell, comprising: contacting a cancer cell with a fusion peptide having a structure: A-B-C or C-B-A whereby invasiveness of the cancer cell is reduced or retarded, wherein A is a protein transduction domain which translocates attached macromolecules across cellular membranes; wherein B is a spacer of 0-5 amino acid residues; wherein C is a polypeptide of 6-15 amino acid residues, wherein C comprises all or a portion of PYEKVSAGNGGSSLS (SEQ ID NO: 1), and wherein the portion of C comprises GGSSLS (SEQ ID NO: 2), or wherein at least one of said 6-15 amino acid residues is conservatively substituted such that an uncharged polar amino acid replaces an uncharged polar amino acid, or a non-polar amino acid replaces a non-polar amino acid residue, or an acidic amino acid replaces an acidic amino acid, or wherein one of said 6-15 amino acid residues is substituted with an A residue.