Patent ID: 6958331

Claim:
A compound of formula IA wherein R 5A is —X A —R 6A or —N(R 7A )R 8A , wherein X A is piperidinylene or piperazinylene, R 6A is H, C 1 -C 4 alkyl, C 3 -C 4 alkenyl, C 3 -C 4 alkinyl, C 1 -C 4 (alkoxyalkyl), C 1 -C 4 (carboxyalkyl), a C 5 -C 7 heterocyclic group or phenyl-C 1 -C 4 alkyl; R 7A is amino-C 2 -C 4 alkyl or mono- or di-(C 1 -C 5 alkyl)amino-C 2 -C 5 alkyl, and R 8A is H, C 1 -C 4 alkyl or has the meanings as given for R 7A ; X 1 is a divalent group of formula IA′ wherein n is zero or 1; X 3 is CH or N; (a) X 4 is a direct bond, R 3A and R 4A together are ethylene and m is 2; or (b) X 4 is a direct bond, R 3A is H, C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkinyl, C 7 -C 10 aralkyl, or C 6 -C 9 heteroaralkyl, R 4A is H and m is 1 or 2 or 3; or (c) X 4 is —CH(R 12 )—, R 3A is H and R 4A and R 12 together are propylene and m is 1, or ethylene and m is 2; X 2 is a divalent group of formula IA″ wherein X 3 is CH or N; and R 11 is C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl or —NR 1A R 2A , wherein R 1A and R 2A independently are C 1 -C 4 alkyl or, together with the N-atom to which they are attached, represent a 5 to 7 membered heterocyclic ring; and R 9 and R 10 independently are a phenyl or pyridine ring; and salts thereof.