Patent ID: 7714120

Claim:
An isolated nucleic acid comprising a polynucleotide encoding an antibody, or an antigen-binding portion thereof, that specifically binds human IL-1β, comprising a polynucleotide encoding a light chain variable region and a polynucleotide encoding a heavy chain variable region selected from the group consisting of: (a) a light chain variable region of SEQ ID NO:60, and a heavy chain variable region of SEQ ID NO:55; (b) a light chain variable region of SEQ ID NO:61, and a heavy chain variable region of SEQ ID NO:56; (c) a light chain variable region of SEQ ID NO:62, and a heavy chain variable region of SEQ ID NO:57; (d) a light chain variable region of SEQ ID NO:63, and a heavy chain variable region of SEQ ID NO:59; and, (e) a light chain variable region of SEQ ID NO:64, and a heavy chain variable region of SEQ ID NO:58.