Patent ID: 8344111

Claim:
An isolated monoclonal antibody specifically binding nicotine, wherein said monoclonal antibody is a human monoclonal antibody, and (a) wherein said monoclonal antibody comprises at least one heavy chain variable region (HCVR), wherein said HCVR comprises: (i) one heavy chain complementarity determining region (HC CDR)1, wherein said HC CDR1 comprises the peptide of SEQ ID NO:1; (ii) one HC CDR2, wherein said HC CDR2 comprises the peptide of SEQ ID NO:2; and (iii) one HC CDR3, wherein said HC CDR3 comprises the peptide of any one of SEQ ID NOs 3 and 4; and (b) wherein said monoclonal antibody comprises at least one light chain variable region (LCVR), wherein said LCVR comprises: (i) one light chain complementarity determining region (LC CDR)1, wherein said LC CDR1 comprises the peptide of any one of SEQ ID NOs 5, 6, and 7; (ii) one LC CDR2, wherein said LC CDR2 comprises the peptide of SEQ ID NO:8; (iii) one LC CDR3, wherein said LC CDR3 comprises the peptide of any one of SEQ ID NOs 9 and 10.