Patent ID: 8633034

Claim:
A method for evaluating the aggregation of a proteinaceous material in a suspension comprising an organopolysiloxane, comprising: (a) providing an aqueous suspension of a fluorescently-labeled organopolysiloxane and a fluorescently-labeled proteinaceous material; (b) measuring relative particle fluorescence intensity of the fluorescently-labeled organopolysiloxane and the fluorescently-labeled proteinaceous material using fluorescence-activated particle sorting; and (c) evaluating the aggregation of the proteinaceous material by comparing the relative intensity of the fluorescently-labeled organopolysiloxane to the relative intensity of the fluorescently-labeled proteinaceous material, wherein the relative intensity of the fluorescently-labeled organopolysiloxane as compared to the relative intensity of the fluorescently-labeled proteinaceous material indicates the aggregation of the proteinaceous material.