Patent ID: 6911424

Claim:
A method for the treatment of hepatitis B infection in humans, comprising administering to a patient in need thereof an effective treatment amount of a 2′-fluoro-β-D-nucleoside of the formula: wherein Base is a purine base; R 1 is OH, H, OR 3 , N 3 , CN, halogen, CF 3 , lower alkyl, amino, loweralkylamino, or di(lower)alkylamino; R 2 is H, monophosphate, diphosphate, triphosphate, a stabilized phosphate prodrug, acyl, phosphate, phosphonate, a lipid or an amino acid; and R 3 is acyl, alkyl, phosphate, or other pharmaceutically acceptable leaving group which when administered in vivo, is capable of being cleaved to the parent compound, or a pharmaceutically acceptable salt thereof, optionally in combination with a pharmaceutically acceptable carrier.