Patent ID: 8524671

Claim:
A method for the treatment of an inflammatory condition of a mammal, comprising the step of administering to a patient in need thereof, a therapeutically effective amount of a cyclosporin A derivative represented by the following formula: wherein R 1 is S-Alk-R wherein Alk is an alkylene linkage and, R is —N═C(NR 3 R 4 )(NR 5 R 6 ), wherein R 3 -R 6 is H, Alk, Ar or (CH 2 )nAr wherein Ar is an aryl group and n is an integer of from 1 to 13 or R 3 and R 4 or R 4 and R 5 , together may be —CH 2 —CH 2 — or —CH 2 —CH 2 —CH 2 —, and R 2 is —CH 2 CH(CH 3 ) 2 , —CH 2 C(OH)(CH 3 ) 2 , —CH(CH 3 ) 2 or —CH(CH 3 )CH 2 CH 3 .