Patent ID: 8535934

Claim:
A lung care system comprising: a portable multiple use module including a portable chassis; a first electromechanical connector disposed on the portable multiple use module; a single use disposable module including: a disposable structure including a second electromechanical connector disposed thereon that is sized and shaped for interlocking the single use disposable module with the multiple use module for electromechanical inter-operation with the multiple use module, wherein the second electromechanical connector is configured to electromechanically couple to the first electromechanical connector, and a lung chamber assembly having a first interface for allowing a flow of perfusion fluid into the lung, a second interface for allowing ventilation of the lung, and a third interface for allowing a flow of the perfusion fluid away from the lung; a pump adapted to flow the perfusion fluid into and away from the lung; and a respiratory gas source having a predetermined composition of oxygen; a ventilator coupled to the respiratory gas source and the second interface; a gas exchange device configured to controllably alter a composition of a first gas component in the perfusion fluid; at least one processor coupled to a non-transitory memory storing instructions that, when executed by the at least one processor: cause the ventilator to ventilate the lung by flowing respiratory gas into the lung via the second interface in periodic breaths containing a predetermined volume of and pressure of the respiratory gas; cause the ventilator to maintain a predetermined minimum positive end-expiratory pressure, and cause the gas exchange device to modulate the composition of the first gas component in the perfusion fluid as a function of the amount of oxygen in the respiratory gas provided to the lung; wherein the lung chamber assembly includes a flexible membrane that suspends the lung within the lung chamber assembly for supporting the lung and maintaining a shape of the lung.