Patent ID: 8748598

Claim:
A compound having the formula I: wherein R 1 , R 2 , R 3 , R 4 and R 5 are as indicated in one of the following combinations: R 1 =OCOCH 3 , R 2 =H, R 3 =CON(CH(CH 3 ) 2 ) 2 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 CH 2 CH 3 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH(CH 3 ) 2 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CON(CH 3 ) 2 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 COOCH 3 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 (CH 2 ) 4 CH 2 NH 2 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 (CH 2 ) 2 CH 2 NH 2 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 (CH 2 ) 5 CH 2 NH 2 , R 4 & R 5 =O; R 1 =OH, R 2 =H, R 3 =CON(CH 2 CH 2 ) 2 O, R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CON(CH 2 CH 2 ) 2 O, R 4 & R 5 =O; R 1 =OH, R 2 =H, R 3 =CON(CH 2 CH 2 ) 2 NCH 2 CH 2 OH, R 4 & R 5 =O; R 1 =OOCH 3 , R 2 =H, R 3 =CON(CH 2 CH 2 ) 2 NCH 2 CH 2 OH, R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =Imidazole-1-carbonyl, R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =2-Aminoindane-N-carbonyl, R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHC 6 H 5 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 3 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONH(2-C 6 H 4 Br), R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CON(CH 3 )CH 2 CH 2 OH, R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONH(p-C 6 H 4 OH), R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHNHC 6 H 5 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 NHCHO, R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 N(CH 2 CH 2 OH) 2 ., R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 NHCOCHCH(3,4-C 6 H 3 O 2 CH 2 ), R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 NH 2 , R 4 & R 5 =H; R 1 =OCOCH 3 , R 2 =H, R 3 =CONH 2 , R 4 & R 5 =H; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 OH, R 4 & R 5 =H; R 1 =OCOCH 3 , R 2 =H, R 3 =CON(CH 2 CH 2 ) 2 NH, R 4 & R 5 =H; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH 2 CH 2 NHCH 3 , R 4 & R 5 =O; R 1 =OCOCH 3 , R 2 =H, R 3 =CONHCH(COOCH 3 )CH 2 CH 2 COOCH 3 , R 4 & R 5 =O; R 1 & R 2 =NOH, R 3 =CONH 2 , R 4 & R 5 =O; and R 1 & R 2 =NHCOCH 3 , R 3 =COOCH 3 , R 4 & R 5 =O.