Patent ID: 7935690

Claim:
A method for maintaining a therapeutically effective concentration of an androgen in the blood serum of a male for treating of hypogonadism which comprises transdermally delivering to the male by applying to the skin a composition which is in the form of a topical gel, which has a viscosity of about 500 to about 20,000 cps and a pH of about 3 to about 9, and comprises: (A) about 0.1 to about 5 wt. % of an androgen selected from the group consisting of testosterone, DHEA (dehydroepiandrosterone), pregnenolone, progesterone, 17-OH-progesterone, and androsterone; (B) about 8 to about 25 wt. % of a macrocyclic enhancer selected from the group consisting of 3-methylcyclopentadecanone, 9-cycloheptadecen-1-one, cyclohexadecanone, cyclopentadecanone, oxacyclohexadecan-2-one and mixtures thereof; and (C) about 0.1 to about 10 wt. % of a thickening agent; (D) a mixture of solvents which include about 40 wt. % to about 80% of ethanol.