Patent ID: 7909886

Claim:
A method of repairing or replacing a damaged tissue comprising: implanting in a patient a non-antigenic prosthesis comprising two or more superimposed, bonded layers of collagenous tissue of each layer comprises tunica submucosa of small intestine, wherein the collagenous tissue does not include the tunica muscularis and tunica mucosa, wherein the two or more layers of collagenous tissue are separated from surrounding layers of the small intestine, wherein the two or more layers of collagenous tissue have been sterilized with peracetic acid and crosslinked with a crosslinking agent that permits bioremodeling, wherein the crosslinking agent is 1-ethyl-3-(3-dimethylaminopropyl) carbodiimidc hydrochloride, wherein the two or more layers of collagenous tissue are completely bioremodelable and when implanted into a mammalian patient undergo controlled biodegradation occurring with adequate living cell replacement such that the implanted prosthesis is remodeled by the patient's living cells, and wherein the implanted prosthesis is an abdominal wall patch, a pericardial repair patch, a hernia repair device, a vascular patch, an intracardiac patch or a replacement heart valve.