Patent ID: 7071205

Claim:
A compound of the formula: wherein: R 1 is selected from the group of hydrogen, C 1 –C 4 alkyl, C 1 –C 4 haloalkyl, C 1 –C 4 heteroalkyl, COR 11 , CO 2 R 11 , SO 2 R 11 , and CONR 11 R 12 ; R 2 and R 3 each independently is selected from the group of hydrogen, C 1 –C 6 alkyl, and C 1 –C 6 haloalkyl; or R 2 and R 3 taken together form a cycloalkyl ring of from three to twelve carbons; R 4 through R 7 each independently is selected from the group of hydrogen, F, Cl, Br, CN, OR 11 , C 1 –C 4 alkyl, C 1 –C 4 haloalkyl, and C 1 –C 4 heteroalkyl; or R 5 and R 7 taken together form a bond; or R 6 and R 7 taken together are selected from the group of methylidene, mono-substituted methylidene, di-substituted methylidene and carbonyl; R 8 through R 10 each independently is selected from the group of hydrogen, F, Cl, Br, I, NO 2 , CN, OR 11 , NR 11 R 12 , SR 11 , COR 11 , CO 2 R 11 , CONR 11 R 12 , C 1 –C 8 alkyl, C 1 –C 8 heteroalkyl, C 1 –C 8 haloalkyl, allyl, C 2 –C 8 alkenyl and C 2 –C 8 alkynyl; R 11 and R 12 each is independently selected from the group of hydrogen, C 1 –C 4 alkyl, C 1 –C 4 heteroalkyl, and C 1 –C 4 haloalkyl; R 13 is hydrogen; R 14 through R 20 each independently is selected from the group of hydrogen, F, Cl, Br, OR 11 , C 1 –C 4 alkyl, C 1 –C 4 haloalkyl, and C 1 –C 4 heteroalkyl; or R 14 and R 15 taken together are selected from the group of methylidene, carbonyl and thiocarbonyl; or R 16 and R 17 taken together are selected from the group of methylidene, mono-substituted methylidene, di-substituted methylidene, carbonyl and thiocarbonyl; or R 14 and R 16 taken together form a bond or “—O—” bridge; or R 16 and R 18 taken together form a bond when n is 1; or R 16 and R 19 taken together form a bond when n is 0; R 21 is hydrogen; or R 21 and R 20 taken together form a bond; n is 0, 1, 2, or 3; or a pharmaceutically acceptable salt thereof.