Patent ID: 7807198

Claim:
A composition comprising: a linear cyclodextrin-containing polymer, a therapeutic agent, and an inclusion complex of said polymer and a complexing agent, wherein the complexing agent comprises a ligand for cell targeting, and the polymer has host functionality, and wherein said complexing agent is a compound of the formula: wherein J is —NH—, —C(═O)NH—(CH 2 ) d —, —NH—C(═O)—(CH 2 ) d —, —CH 2 SS—, —C(═O)O—(CH 2 ) e —O—P(═O)(O—(CH 2 ) e -Ad)O—, —NH(C═O)—CH(R 1 )—NH—(C═O)—CH(R 1 )—NH—; Ad is adamantyl; R 1 is —(CH 2 ) a —CO 2 H, an ester or salt thereof; or —(CH 2 ) a —CONH 2 ; PEG is —O(CH 2 CH 2 O) z —, where z varies from 2 to 500; L is H, —NH 2 , —NH—(C═O)—(CH 2 ) e —(C═O)—CH 2 , —S(═O) 2 —HC═CH 2 —, —SS—, —C(═O)O— or a carbohydrate residue; Functional Group comprises a ligand for cell targeting; a is 0 or 1; b is 0 or 1; d ranges from 0 to 6; e ranges from 1 to 6; n ranges from 0 to 6; y is 1; and x is 1.