Patent ID: 7714101

Claim:
An isolated polypeptide useful for generating a protective effect against porcine reproductive and respiratory syndrome (PRRS) comprising: a sequence comprising a heterodimer of a matrix protein (M protein) of porcine reproductive and respiratory syndrome virus (PRRSV) and a glycoprotein 5 (GP5) of PRRSV, wherein said GP5 protein has N-glycosylation of an asparagine amino acid located at position 44 of the GP5 protein in North American PRRSV strains, and wherein the position number 44 is determined from sequence alignment with the amino acid sequence of SEQ ID NO:1, or at position 46 of the GP5 protein in European PRRSV strains, wherein the position number 46 is determined from sequence alignment with the amino acid sequence of SEQ ID NO:4.