Patent ID: 8236789

Claim:
An 1-adamantyl azetidin-2-one derivative represented by the following general formula (1) or salt thereof: wherein ring A is a C 6-10 aryl group or a 5- to 14-membered heteroaryl group, wherein R 1 is a hydrogen atom, a halogen atom, a C 1-6 alkoxycarbonyl group, a mono(C 1-8 alkyl)aminocarbonyl group optionally substituted with a C 6-10 aryl group, a carboxyl group or a C 1-6 alkoxycarbonyl group, a di(C 1-8 alkyl)aminocarbonyl group, a C 3-6 cycloalkyl aminocarbonyl group, a C 2-6 alkanoyl group, a formyl group, a hydroxyl group, a carboxyl group or a carbamoyl group; wherein R 2 and R 3 are the same or different and are a C 1-6 alkyl group; wherein R 4 , R 5 , and R 6 are same or different, and are a hydrogen atom, a halogen atom, a C 1-6 alkyl group, a halo C 1-6 alkyl group, a C 1-6 alkoxy group, a halo C 1-6 alkoxy group, a C 1-6 alkylthio group, a C 1-6 alkylsulfinyl group, a C 1-6 alkylsulfonyl group, an amino group, a C 6-10 aryl group, a mono(C 1-8 alkyl)amino group, a di(C 1-8 alkyl)amino group, a C 2-6 alkanoylamino group or a formylamino group, or R 4 and R 5 , or R 5 and R 6 together with the atom to which these are attached form a C 1-3 alkylenedioxy group, wherein R 7 and R 8 are the same or different and are a hydrogen atom or a C 1-6 alkyl group, or together with the atom to which these are attached form a C 3-6 cyclic hydrocarbon group, and wherein n represents an integer of 0 or 1.