Patent ID: 8440624

Claim:
A compound having the following formula (I): [R 1 R 2 N—CH(Ra)—CO] a -(AA 1 ) m -(AA 2 ) b -X 1 —X 2 —X 3 —Y 1 —Y 2 —Y 3 —X 4 —[NH—CH(Rb)—COOR 3 ] c (I) wherein: R 1 , R 2 , R 3 each independently represent: H, a C 2 -C 22 optionally hydroxylated and/or sulphured linear hydrocarbon group which may be saturated or unsaturated, a C 3 -C 22 optionally hydroxylated and/or sulphured branched or cyclic hydrocarbon group which may be saturated or unsaturated, or a biotin group, wherein at least one of R 1 and R 2 may alternatively be a protective group or a blocking group; Ra and Rb each independently represent: H, a C 1 -C 4 linear alkyl group, or a C 3 -C 4 branched alkyl group, each alkyl group optionally being substituted by one or more substituents selected from the group consisting of: OH, SH, COOH, CONH 2 , NH 2 —S—CH 3 , NH—C(NH)—NH 2 or by a cyclic or heterocyclic aromatic group; X 1 is arginine (R), aspartic acid (D), or glutamic acid (E); X 2 is glutamine (Q), glutamic acid (E) or asparagine (N); X 3 is proline (P); X 4 is aspartic acid (D) or glutamic acid (E); Y 1 is leucine (L), methionine (M) or isoleucine (I); Y 2 is leucine (L); Y 3 is valine (V), leucine (L) or methionine (M); AA 1 is an amino acid; AA 2 is glutamic acid (E); m=1; b=1; and each of a and c=0 or 1, wherein each amino acid may independently be in a L, D or DL configuration, with the proviso that when X 1 is arginine (R), then Y 3 is not methionine (M).