Patent ID: 8742097

Claim:
A compound of formula (I) wherein A is —CH 2 —O—; wherein X is N, Y is CR 9 and Z is CR 10 , or X is CH, Y is N and Z is CR 10 ; or X is N, Y is CR 9 and Z is N; or X is N, Y is N and Z is CR 10 ; R 1 and R 2 are each independently alkyl, aryl optionally substituted by one halo or heteroaryl optionally substituted by one halo, wherein one of R 1 or R 2 is alkyl; R 3 is halo, haloalkyl, —C(O)R 4 , or —C(O)NR 5 R 6 ; R 4 is alkoxy; R 5 is alkyl, haloalkyl, hydroxyalkyl, halohydroxyalkyl, —(CH 2 ) n -cycloalkyl, —(CH 2 ) n -heterocycloalkyl, or —(CH 2 ) n —NR 7 R 8 , wherein said heterocycloalkyl is optionally substituted by one or two alkyl or oxo; R 6 is H, alkyl, or is alkylene together with R 9 or R 10 ; or R 5 and R 6 together with the nitrogen to which they are bound form a heterocycloalkyl optionally substituted by one or more oxo; R 7 and R 8 are each independently alkyl; R 9 and R 10 are each independently H, or one of R 9 or R 10 is alkylene together with R 6 ; and n is an integer from 0 to 1; or a pharmaceutically acceptable salt or ester thereof.