Patent ID: 8022061

Claim:
A compound having formula IV or V: or a pharmaceutically acceptable salt thereof, wherein: V is cyclo(C 3 -C 7 )alkyl, heterocyclo(C 3 -C 7 )alkyl, aryl, heteroaryl, aryl(C 1 -C 4 )alkyl, or heteroaryl(C 1 -C 4 )alkyl; W is a single bond, (C 1 -C 5 )alkylene, (C 2 -C 5 )alkenylene, —O—, —S(O) k —, —C(O)—, —NR 6 — or —CH 2 NR 6 —; R 1 is a substituted or unsubstituted member selected from furyl, isoxazolyl, oxazolyl, thiazolyl, pyrrolyl, thienyl, piperidinyl, cyclobutyl and cyclopentyl; R 2 is halogen, (C 1 -C 6 )alkyl, —CN, halo(C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, halo(C 1 -C 6 )alkoxy or (C 2 -C 6 )alkenyl; optionally, R 2 and W taken together form a 5- or 6-membered fused ring containing 0, 1, 2 or 3 heteroatoms selected from O, S, and N; R 4 is (C 1 -C 8 )alkyl, hetero(C 2 -C 8 )alkyl, cyclo(C 3 -C 7 )alkyl, aryl, heteroaryl, aryl(C 1 -C 4 )alkyl or heteroaryl(C 1 -C 4 )alkyl; R 6 is hydrogen, (C 1 -C 8 )alkyl, fluoro(C 1 -C 4 )alkyl, hetero(C 2 -C 8 )alkyl, aryl, heteroaryl, aryl(C 1 -C 4 )alkyl, —C(O)R′, —CO 2 R′, —C(O)NR′R″, —S(O) k R′ or —S(O) k NR′R″; each R′ and R″ is independently hydrogen, (C 1 -C 6 )alkyl, cyclo(C 3- C 8 )alkyl, aryl or aryl(C 1 -C 4 )alkyl; and each subscript k is independently 0, 1 or 2.