Patent ID: 7122552

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: each A is independently nitrogen; R 1 and R 2 are each independently selected from halogen, CN, NO 2 , R 4 , OR 4 , SR 4 , N(R 4 ) 2 , NH(R 4 ), NHCH 2 (R 4 ) 2 , NHC(O)R 4 , NHCO 2 R 4 , NHSO 2 R 4 , NHC(O)N(R 4 ) 2 , or NHSO 2 N(R 4 ) 2 , provided that: at least one of R 1 and R 2 is selected from NH(R 4 ), NHCH 2 (R 4 ) 2 , NHC(O)R 4 , NHCO 2 R 4 , NHSO 2 R 4 , NHC(O)N(R 4 ) 2 , or NHSO 2 N(R 4 ) 2 ; R 3 is an optionally substituted ring selected from: (a) a 3–8 membered monocycic or 8–10 membered bicyclic saturated or unsaturated ring; (b) a 3–7 membered heterocyclic ring having 1–3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or (c) a 5–6 membered monocyclic or 8–10 membered bicyclic heteroaryl ring having 1–4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each R 4 is selected from R or Ar; each R is independently selected from hydrogen or an optionally substituted C 1-6 aliphatic group, wherein: two R bound to the same nitrogen atom are optionally taken together with the nitrogen to form a 3–7 membered saturated, partially unsaturated, or fully unsaturated ring having 0–2 heteroatoms, in addition to the nitrogen bound thereto, independently selected from nitrogen, oxygen, or sulfur; and each Ar is an optionally substituted ring selected from: (a) a 3–8 membered monocyclic or 8–10 membered bicyclic saturated, partially unsaturated, or aryl ring; (b) a 3–7 membered heterocyclic ring having 1–3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or (c) a 5–6 membered monocyclic or 8–10 membered bicyclic heteroaryl ring having 1–4 heteroatoms independently selected from nitrogen, oxygen, or sulfur.