Patent ID: 8557298

Claim:
A medicament adapted for intralesional injection, the medicament consisting of: a hydrophilic vehicle containing a halogenated xanthene having a structure of Formula I wherein X is selected from the group consisting of hydride, bromide, chloride, and iodide, Y is selected from the group consisting of hydride, bromide, chloride, and iodide, and Z is selected from the group consisting of hydride, bromide, and chloride, such that said halogenated xanthene is Rose Bengal, wherein said halogenated xanthene is at a concentration in the range of from 1% to 20%, wherein R 1 is an ion selected from the group consisting of hydrogen ion (H + ) and sodium ion (Na + ), and R 2 is an ion selected from the group consisting of hydrogen ion (H + ) and sodium ion (Na + ), said halogenated xanthene being dissolved in said vehicle at a concentration of from greater than 1% to less than 20%; and an electrolyte consisting of sodium chloride; wherein the electrolyte is present in said vehicle at a concentration of 0.1-2%, or wherein the electrolyte is present in said vehicle at a level sufficient to provide an osmolality of the medicament of greater than 100 mOsm/kg, said medicament having a pH in the range from 4 to 10, and wherein: said medicament is sterile; said medicament contains pyrogenic material at a level of no more than 10 Endotoxin Units per mL; said medicament contains particulate material at a level of no more than 300 particles of size 25 microns or larger and no more than 3000 particles of size 10 microns or larger; and said medicament includes labeling in conformance with International Conference on Harmonization standards specifying that said medicament is for injection.