Patent ID: 8535667

Claim:
A method for detecting the presence of cancer cells that expresses a human colorectal and pancreatic carcinoma-associated antigen (CPAA) in a subject comprising: (a) administering to said subject having or suspected of having cancer a labeled monoclonal antibody or antigen-binding region thereof, that binds the human CPAA, and (b) detecting the presence of human CPAA specifically bound by said antibody, wherein the presence of said detected human CPAA is indicative of cancer cells that express the human CPAA specifically bound by the antibody or antigen-binding region thereof, and wherein said monoclonal antibody or antigen-binding region thereof comprises the light chain CDR1 amino acid sequence of SEQ ID NO: 7, light chain CDR2 amino acid sequence of SEQ ID NO: 8, and light chain CDR3 amino acid sequence of SEQ ID NO: 9, and wherein said monoclonal antibody or antigen-binding region thereof comprises the heavy chain CDR1 amino acid sequence of SEQ ID NO: 10, heavy chain CDR2 amino acid sequence of SEQ ID NO: 11, and heavy chain CDR3 amino acid sequence of SEQ ID NO: 12.