Patent ID: 8119652

Claim:
A compound represented by the following structural formula: wherein X is A, B, D, E, G, J, K, M and P are independently selected from CR 1 2 , NR 1a , C(O) and O; R is NH 2 or OH; is phenyl or pyridyl; is phenyl; each R 1 is independently 1) hydrogen, 2) C 1 -C 6 alkyl, 3) (CR 6 2 ) n R 10 , 4) (CR 6 2 ) n C(O)R 4 , 5) (CR 6 2 ) n C(O)OR 4 , 6) (CR 6 2 ) n C(O)NR 5 2 , 7) (CR 6 2 ) n S(O) 2 R 4 , 8) (CR 6 2 ) n OR 4 , 9) (CR 6 2 ) n NR 5 (SO 2 )R 4 , 10) (CR 6 2 ) n NR 5 2 , 11) (CR 6 2 ) n NR 5 C(O)OR 4 , 12) halo, or 13) aryl; each R 1a is independently 1) hydrogen, 2) C 1 -C 6 alkyl, 3) (CR 6 2 ) n R 10 , 4) (CR 6 2 ) n C(O)R 4 , 5) (CR 6 2 ) n C(O)OR 4 , 6) (CR 6 2 ) n C(O)NR 5 2 , or 7) (CR 6 2 ) n S(O) 2 R 4 ; L 1 is a bond R 3 is hydrogen, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl; each R 4 is independently 1) H, 2) C 1 -C 6 alkyl, 3) aryl, or 4) heterocyclyl, wherein alkyl, aryl or heterocyclyl is optionally substituted with C 1 -C 6 alkyl; each R 5 is independently 1) hydrogen, 2) C 1 -C 6 alkyl, or 3) aryl, which may be optionally substituted with 1 to 3 substituents selected from C 1 -C 6 alkyl, aryl, heteroaryl or halo; each R 6 is independently 1) hydrogen, 2) C 1 -C 6 alkyl, 3) aryl, 4) OR 11 , 5) halo, or 6) NR 11 ; wherein the alkyl or aryl may be optionally substituted with 1 to 3 substituents selected from the group consisting of C 1 -C 6 alkyl, aryl, heteroaryl and halo; each R 10 is independently 1) aryl, and 2) heterocyclyl, which may be optionally substituted; each R 11 is independently hydrogen, C 1 -C 6 alkyl, or aryl, wherein said alkyl and aryl groups are optionally substituted; n is independently selected from 0, 1, 2, 3 and 4; q is 1; or a stereoisomer or a pharmaceutically acceptable salt thereof.