Patent ID: 7923019

Claim:
Antibiotic/s containing bone substitute material, comprising a mixture of granules compacted in a mold with a pressing force of at least 30 kN of the following components: calcium sulfate dihydrate, and at least one member selected from the group consisting of calcium carbonate, β-tricalcium phosphate, calcium hydrogen phosphate, calcium hydrogen phosphate dihydrate, magnesium carbonate, trimagnesium phosphate, magnesium hydroxide and magnesium oxide, and at least one member selected from the group consisting of aminoglycoside antibiotics, lincosamide antibiotics, glycopeptide antibiotics, macrolide antibiotics, ketolide antibiotics, nitroimidazoles, fluoroquinolone antibiotics, oxazolidinone antibiotics, steroid antibiotics, and fungicidal/fungistatic antibiotics, with the granules being partly or entirely sheathed with a layer of one or more substances selected from the group consisting of glycerol tripalmitate, glycerol tristearate, glycerol trilaurate and 1-hexadecyl alcohol which connects individual granules with each other, wherein the compacted mixture has no macropores of pore diameters larger than 50 μm.