Patent ID: 7943749

Claim:
A compound of formula I: wherein: each R 1 is, independently, H or a hydroxyl protecting group; each R 2 and R 3 is, independently, H, an amino protecting group or together R 2 and R 3 that are connected to the same nitrogen atom form a cyclic protecting group that can include additional heteroatoms selected from N, O and S; Z has the formula: —(CH 2 ) m -L 1 -(CH 2 ) mm -Q 1 wherein: L 1 is S, O or NJ 1 ; m is from 1 to about 8; mm is 0 or from 1 to about 8; Q 1 is H, OH, halogen, NJ 1 J 2 , C 2 -C 20 alkenyl, substituted C 2 -C 20 alkenyl, C 2 -C 20 alkynyl, substituted C 2 -C 20 alkynyl, C 5 -C 20 aryl, substituted C 5 -C 20 aryl, heteroaryl, substituted heteroaryl, a heterocyclic radical, a substituted heterocyclic radical or a substituted or unsubstituted mono or poly cyclic structure that can be unsaturated, partially saturated or fully saturated and can include one or more heteroatoms selected from O, N and S; each of said substituted groups, is, independently, mono or poly substituted with substituent groups selected from halogen, hydroxyl, C 1 -C 20 alkyl, substituted C 1 -C 20 alkyl, C 2-20 alkenyl, substituted C 2 -C 20 alkenyl, C 2 -C 20 alkynyl, substituted C 2 -C 20 alkynyl, C 5 -C 20 aryl or substituted C 5 -C 20 aryl, heteroaryl or a substituted heteroaryl, haloalkyl, alkoxy, thioalkoxy, haloalkoxy, —NJ 1 J 2 , azido, carboxy, acyl, ═O, cyano, nitro, mercapto, sulfide, sulfonyl and sulfoxide and wherein said substituent groups are optionally protected; and J 1 and J 2 are each, independently, H, C 1 -C 20 alkyl, substituted C 1 -C 20 alkyl, C 1 -C 20 aminoalkyl or an amino protecting group or J 1 and J 2 are joined in a heterocyclic compound including the nitrogen atom connecting them and optionally including from 1 to 2 additional heteroatoms selected from O, N, and S.