Patent ID: 7838528

Claim:
A compound of formula I wherein: R1, R2 and R3 independently of one another are selected from the group consisting of H, (C 1 -C 10 -alkyl, (C 3 -C 10 )-cycloalkyl, (C 2 -C 10 )-alkenyl, (C 2 -C 10 )-alkynyl, (C 6 -C 10 )-aryl, and heterocycle, where the alkyl, cycloalkyl, alkenyl, alkynyl, aryl and heterocycle [R-]groups may be substituted one or more times by F, Cl, Br, I, CN, NO 2 , SH, OH, (C 1 -C 6 )-alkyl, —CF 3 , —OCF 3 , —SCF 3 , (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, OR7, OP(O)(OR7) 2 , NR7R8, NR7CONR7R8, COR7, OCOR7, OCOOR7, COOR7, CONR7R8, OCONR7R8, (C 1 -C 6 )-alkylene-OR7, (C 1 -C 6 )-alkylene-NR7R8, (C 1 -C 6 )-alkylene-NR7SO 2 R7, (C 1 -C 6 )-alkylene-SR7, alkylene-S(O)R7, alkylene-S(O) 2 R7, alkylene-S(O) 2 NR7R8, (C 1 -C 6 )-alkylene-COR7, (C 1 -C 6 )-alkylene-COOR7, (C 1 -C 6 )-alkylene-CONR7R8, SR7, SOR7, SO 2 R7, SO 2 NR7R8, NR7SO 2 R7, (C 1 -C 6 )-alkylene-(C 3 -C 10 )-cycloalkyl, (C 1 -C 6 )-alkylene-(C 6 -C 10 )-aryl, (C 1 -C 6 )-alkylene-heterocycle, (C 3 -C 10 )-cycloalkyl, (C 6 -C 10 )-aryl or heterocycle; R7 and R8 independently of one another are selected from the group consisting of H, (C 1 -C 6 )-alkyl, —CF 3 , (C 3 -C 10 )-cycloalkyl, (C 6 -C 10 )-aryl, heterocycle, (C 1 -C 6 )-alkylene-CONR9R10, CONR9R10, (C 1 -C 6 )-alkylene-COOR9, COOR9, COR9, (C 1 -C 6 )-alkylene-COR9, (C 1 -C 6 )-alkylene-OR9, (C 1 -C 6 )-alkylene-NR9R10, (C 1 -C 6 )-alkylene-SR9, (C 1 -C 6 )-alkylene-S(O)R9, (C 1 -C 6 )-alkylene-S(O) 2 R9, S(O)R9, S(O) 2 R9, (C 1 -C 4 )-alkylene-(C 6 -C 10 )-aryl and (C 1 -C 4 )-alkylene-heterocycle; R9 and R10 independently of one another are selected from the group consisting of H, (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylene-(C 6 -C 10 )-aryl, —(C 6 -C 10 )-aryl, heterocycle, and (C 1 -C 6 )-alkylene-heterocycle; R4 and R5 together form the group —CH 2 —CH 2 —NH—, where R6 is H, or R5 and R6 together form the group —CH 2 —NH—CH 2 —, where R4 is H; or a physiologically tolerated salt thereof.