Patent ID: 8299093

Claim:
A method for disrupting HIV assembly and replication comprising: administering to a patient in need thereof a pharmaceutical composition comprising a pharmaceutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt or ester thereof, wherein R 1 is substituted or unsubstituted phenyl, or substituted or unsubstituted furanyl; R 2 is substituted or unsubstituted benzyl, or substituted or unsubstituted alkyl furanyl; R 3 is a moiety selected from the group consisting of H, and substituted or unsubstituted (C 1-6 )alkyl; Z is C═O or C═S; and T, U, V, W and X are independently selected from CR 4 or N, wherein R 4 is a moiety selected from the group consisting of hydrogen, substituted or unsubstituted (C 1-6 )alkyl, substituted or unsubstituted (C 1-6 )alkoxy, hydroxyl alkyl, Cl, Br, and F; disrupting HIV assembly and replication.