Patent ID: 7871986

Claim:
A method for eliciting an immune response against prostate specific antigen (PSA) in a human comprising: (a) administering to the human a priming inoculation of an effective amount of a first recombinant virus, wherein the virus is characterized by encoding a prostate specific antigen oligo-epitope peptide (PSA-OP); and (b) administering to the human one or more boosting inoculations of an effective amount of a second recombinant virus of a different genus, wherein the virus is characterized by encoding the PSA-OP, wherein the PSA-OP consists of the amino acid sequence: (SEQ ID NO: 4) (a) F L T P K K L Q C V D L 141 142 143 144 145 146 147 148 149 150 151 152 H V I S N D V C A Q V H 153 154 155 156 157 158 159 160 161 162 163 164 P Q K V T K or (b) SEQ ID NO: 4 wherein valine is substituted for an amino acid residue at one or more positions selected from the group consisting of position 148, position 149, position 160, and position 161, or wherein at least one of the amino acids at positions 151, 152, and 153 is deleted, such that an immune response against PSA is elicited in the human.