Patent ID: 8557520

Claim:
A method to identify a human subject has prostate cancer, comprising: measuring in a test sample of prostate tissue from the subject a level of at least one let-7d gene product and at least one miR-128a prec gene product; comparing the level of the at least one let-7d gene product and the least one miR-128a prec gene product in the test sample from a subject to a control level of at least one corresponding let-7d gene product and at least one miR-128a prec gene product; correlating an increase in the test sample level of let-7d gene product compared to the control level of let-7d gene product, and a decrease in the test sample level of miR-128a prec gene product compared to the control level of miR-128a prec gene product, with a human subject having prostate cancer; and identifying the subject has prostate cancer, if the level of the at least one let-7d gene product in the test sample from the subject is greater than the control level of let-7d gene product, and if the level of the at least one miR-128a prec gene product in the test sample from the subject is less than the control level of miR-128a prec gene product.