Patent ID: 6936077

Claim:
A 1,3-diamino-4-(aminomethyl)-benzene derivative compound of the formula (I), or a physiologically tolerated, water-soluble salt thereof: wherein R1 and R2, independently of one another, each represent hydrogen, a C 1 -C 6 alkyl group, a C 2 -C 4 hydroxyalkyl group or a C 3 -C 4 dihydroxyalkyl group, R3 is hydrogen or a C 1 -C 4 alkyl group, R4 and R5, independently of one another, each represent hydrogen, a C 1 -C 2 alkoxy group, a saturated C 1 -C 6 alkyl group, an unsaturated C 3 -C 6 alkyl group, a C 2 -C 4 hydroxyalkyl group, a C 3 -C 4 dihydroxyalkyl group, a C 2 -C 4 amino alkyl group, a C 2 -C 4 dimethylamino alkyl group, a C 2 -C 4 acetylamino alkyl group, a C 2 -C 4 methoxyalkyl group, a C 2 -C 4 ethoxyalkyl group, a C 1 -C 4 cyanalkyl group, a C 1 -C 4 carboxy alkyl group, a C 1 -C 4 aminocarbonylalkyl group, a pyridyl methyl group, a furfuryl group, a thienyl methyl group, a substituted pyridyl group or a group of formula (II) or R4 and R5 together with N form a ring of formula wherein R6, R7, R8, R9 and R10, independently of one another, each represent hydrogen, a halogen atom, a cyano group, a hydroxy group, a C 1 -C 4 alkoxy group, a C 2 -C 4 hydroxyalkoxy group, a C 1 -C 6 alkyl group, a C 1 -C 4 alkyl thioether group, a mercapto group, a nitro group, an amino group, an alkylamino group, a di(C 1 -C 6 alkyl)amino group, a dihydroxy-(C 3 -C 4 )alkyl)amino group, a di(C 1 -C 4 hydroxyalkyl)amino group, a (C 1 -C 4 hydroxyalkyl)-(C 1 -C 6 alkyl)-amino group, a trifluoromethane group, a —C(O)H group, a —C(O)CH 3 group, a —C(O)CF 8 group, a —Si(CH 3 ) 3 group, a C 1 -C 4 hydroxyalkyl group, a C 2 -C 4 dihydroxyalkyl group, a carboxy group or a pyrrolidine group or two adjacent ones of said R6 to R10 form an —O—CH 2 —O— link, R11 is hydrogen, a hydroxy group, a carboxy group, an amino-carbonyl group or a hydroxymethyl group; R12 is hydrogen or a C 1 -C 6 alkyl group; and n is 0 or 1; with the proviso that at least one of said R1 to R5 groups is not hydrogen.