Patent ID: 7465738

Claim:
A method of treating or ameliorating one or more symptoms produced by Spinal Muscular Atrophy in a patient, comprising the step of administering to said patient a therapeutically effective amount of a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: X is O or S; R 1 is a C 1-6 aliphatic group, C 6-10 aryl ring, heteroaryl ring having 5-10 ring atoms, or heterocyclyl ring having 3-10 ring atoms, each optionally substituted with 0-5 TR 3 ; wherein each TR 3 is independently halogen, CN, NO 2 , or an optionally substituted C 1-4 alkyl, aryl, aralkyl, —N(R′) 2 , —CH 2 N(R′)—OR′, —Ch 2 OR′, —SR′, —CH 2 SR′,—COOR′,—NRCOR′,—CON(R′) 2 , or —S(O) 2 N(R′) 2 ; each R 2 is independently halogen, CN, NO 2 , or an optionally substituted C 1-4 alkyl, aryl, aralkyl, —N(R′) 3 , —CH 2 N(R′) 2 , —OR′, CH 2 OR′, —SR′, CH 2 SR′, —COOR′, NRCOR′, —CON(R′) 2 , or —S(O) 2 N(R′) 2 ; R′ is hydrogen or an optionally substituted C 1-6 aliphatic group, an optionally substituted C 6-10 aryl ring, an optionally substituted heteroaryl ring having 5-10 ring atoms, or an optionally substituted heterocyclyl ring having 3-10 ring atoms; and y is 0, 1, 2 or 3.