Patent ID: 8575205

Claim:
An anti-viral compound having the formula: wherein: R 1 represents a radical selected from the group consisting of —NR 5 R 6 , —SO 2 NR 7 R 8 , hydroxyalkyl, hydroxyalkoxy, polyhydroxyalkyl, alkoxyalkoxy, polyfluoroalkyl, dialkylaminoalkyl, R 9 , —OR 9 , and HET; n being an integer from 1 to 4; R 2 and R 3 are each independently selected from the group consisting of straight or branched chain alkyl and hydrogen; R 4 is a radical selected from the group consisting of a substituted or unsubstituted phenyl radical, an unsubstituted or substituted heterocyclic radical, and —NR 12 R 13 ; R 5 and R 7 are independently selected from the group consisting of alkoxyalkyl, hydroxyalkyl, polyhydroxyalkyl, aralkyl, R 9 , —(C═O)R 14 and —(C═O)R 9 ; R 6 , R 8 , R 12 , and R 13 are independently selected from the group consisting of hydrogen, alkyl, alkoxyalkyl, polyfluoroalkyl, hydroxyalkyl, polyhydroxyalkyl, aralkyl, R 9 , —(C═O)R 15 and —(C═O)R 9 ; or R 5 and R 6 taken together with the nitrogen to which they are attached form a substituted or unsubstituted heterocyclic radical, said heterocyclic radical optionally containing one to two additional heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; or R 7 and R 8 taken together with the nitrogen to which they are attached form a substituted or unsubstituted heterocyclic radical, said heterocyclic radical optionally containing one to two additional heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; said phenyl and heterocyclic radical substituents being at least one selected from the group consisting of alkyl, amino, hydroxy, carbonyl, monoalkylamino, dialkylamino, halogen, and alkoxy; R 9 is a radical of the formula —W—O(C═O)—CH 3 , W being a straight- or branched-chain alkylene group of 1 to 6 carbon atoms; R 10 and R 11 are radicals independently selected from the group consisting of alkyl, halo, haloalkyl, and polyfluoroalkyl; HET represents an unsubstituted or substituted five to seven membered heterocyclic ring containing one to four heteroatoms independently selected from nitrogen, oxygen or sulfur, wherein the point of attachment to the heterocyclic ring is other than at a nitrogen atom, said heterocyclic ring substituents being one or more radicals selected from the group consisting of alkyl, amino, hydroxy, carbonyl, oxo, monoalkylamino, and dialkylamino, and wherein HET is other than pyridine when R 1 is in the 4- position; R 14 is a hydroxyalkyl, alkoxyalkyl or cycloalkyl group; R 15 is an alkyl, hydroxyalkyl, alkoxyalkyl or cycloalkyl group; and prodrugs and pharmaceutically acceptable salts of said compound.