Patent ID: RE45288

Claim:
A compound of the formula: wherein: Y is cyano, heteroaryl (C≦12 ), substituted heteroaryl (c≦12) , or —C(O)R a , further wherein: R a is: hydrogen, hydroxy, halo, amino, azido, mercapto or silyl; or alkyl (C≦12) , alkenyl (C≦12) , alkynyl (C≦12 ), aryl (C≦12) , aralkyl (C≦12) , heteroaryl (C≦12) , heteroaralkyl (C≦12) , alkoxy (C≦12) , alkenyl-oxy (C≦12) , alkynyloxy (C≦12) , aryloxy (C≦12) , aralkoxy (C≦12) , heteroaryloxy (C≦12) , heteroaralkoxy (C≦12) , acyloxy C≦12) , alkylamino (C≦12) , alkoxyamino (C≦12) , dialkylamino (C≦12) , alkenylamino (C≦12) , alkynylamino (C≦12) , arylamino (C≦12) , aralkylamino (C≦12) , heteroarylamino (C≦12) , heteroaralkyl-amino (C≦12) , amido (C≦12) , or a substituted version of any of these groups; X is OR b , or NR b R c , wherein R b and R c are each independently: hydrogen or hydroxy; alkyl (C≦8) , aryl (C≦8) , aralkyl (C≦8) , acyl (C≦8) , alkoxy (C≦8) , aryloxy (C≦8) , acyloxy (C≦8) , alkylamino (C≦8) , arylamino (C≦8) , amido (C≦8) , or a substituted version of any of these groups; or provided that R b is absent when the atom to which it is bound is part of a double bond, further provided that when R b is absent the atom to which it is bound is part of a double bond; or a pharmaceutically acceptable salt, tautomer, or optical isomer thereof