Patent ID: 8163507

Claim:
An in vivo process for the determination of nephritis in a mammal, wherein the determination of nephritis comprises: examining a sample of a body fluid from said mammal for the presence of YB-1 protein and/or at least one of its fragments in said sample; and when YB-1 protein and/or at least one of its fragments is present in said sample, determining a secretion pattern of said YB-1 protein and its fragments in said sample, wherein the fragments are at least one fragment having a size selected from the group of: 8 kDa, 16 kDa, 23 kDa, 28 kDa, 30 kDa, 32 kDa, 35 kDa and ±5 kDa of any of the aforementioned sizes, wherein the presence of YB-1 and at least one of said fragments indicates that the mammal has nephritis.