Patent ID: 7893109

Claim:
A composition comprising an N,N-dihaloamino acid of the formula (I)) A-C(R 1 R o )R(CH 2 ) n —C(YZ)—X′ (I) or a derivative or a pharmaceutical composition thereof; wherein A is Hal 2 N—; Hal is halogen selected from the group consisting of chloro and bromo; R is a carbon-carbon single bond or a divalent cycloalkylene radical with three to six carbon atoms; R 1 is selected from the group consisting of hydrogen, lower alkyl and —COOH; R o is lower alkyl; or R 1 and R o together with the carbon atom to which they attach form a (C 3 -C 6 )cycloalkyl ring; n is 0 or an integer from 1 to 13; Y is hydrogen, lower alkyl, —NH 2 or —NHal 2 ; Z is hydrogen or lower alkyl; and X′ is selected from the group consisting of hydrogen, —SO 3 H, —SO 2 NH 2 , —P(═O)(OH) 2 and —B(OH) 2 ; if R is a divalent cycloalkylene radical, n is 0 or an integer up to and including 11, said divalent cycloalkylene radical R or divalent radical —(CH 2 ) n — being optionally substituted with —NHal 2 ; said derivative being a pharmaceutically acceptable salt, ester with lower alkanols, or lower alkanoyl derivative of the —NH 2 group attached to the carbon atom to which the substituent X′ is attached.