Patent ID: 8268313

Claim:
A method of binding VEGF comprising: (a) contacting VEGF with a protein consisting of a heterologous polypeptide fused to: (i) PFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDG KRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTI IDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRAS VRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTS VHIYDK(amino acids 134 to 331 of SEQ ID NO: 1); or (ii) PELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKS ACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIF ISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLD TLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTH RQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDE KNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSF KSVNTSVHIYDK (amino acids 32 to 331 of SEQ ID NO: 1), wherein said protein is capable of binding VEGF; and (b) forming a complex between VEGF and said protein.