Patent ID: 8212012

Claim:
Compounds according to Formula I: wherein R 1 is alkyl, alkenyl, alkynyl, carbocyclic, heterocyclic, aryl, aralkyl, carboxyl, amido, amino, sulfanyl, sulfenyl, sulfonyl, or ether; or R 1 together with X 2 and the atom to which R 1 is attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; or R 1 together with X 4 and the atom to which R 1 is attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein X 1 is —O—, —CO—, or —NH—; wherein X 2 is —O—, —NR 18 —, —CR 19 —, or —CO—; and wherein R 18 and R 19 are hydrogen, alkyl, alkenyl, or alkynyl; or X 2 together with R 1 and the atom to which R 1 is attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein X 4 is, —CR 20 —, or —N═, wherein R 20 is hydrogen, alkyl, alkenyl, or alkynyl; wherein X 5 , is —CR 21 — or —N═, wherein R 21 is hydrogen, alkyl, alkenyl, alkynyl, or alkoxy; wherein X 6 , is —CR 22 — or —N═, wherein R 22 is hydrogen, alkyl, alkenyl, alkynyl, alkoxy, aryl, aralkyl, halogen, or nitro; or X 6 together with X 9 and the carbon at position 7 form a heterocylic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein X 8 , is —CR 23 — or —N═, wherein R 23 is hydrogen, alkyl, alkenyl, alkynyl, aryl, alkoxy or halogen; wherein X 9 is hydroxyl, —O-cycloalkyl substituted with at least one amino, alkyl, halo, or hydroxyl group, —OAc, —O-azasugar, —O-pyridine, —O-pyrrolino, —O-alcohol, alcohol, ester, amino, amido, carbamate, phosphate ester, or mesylate; and wherein at least one of X 2 , X 4 , X 5 , X 6 , X 8 is not —CR—.