Patent ID: 8332028

Claim:
An electrotransport device for delivering therapeutic lithium ions to a mammalian subject, said device comprising: a solid lithium donor metal electrode that is both a source of the therapeutic ions and an anode of a galvanic couple formed with a cathode applied to a body component of the mammalian subject that provides an electro-motive force to drive the ions of the lithium donor metal electrode into the subject; a lithium ion conductive protective architecture having a first and second face, said first face positioned on the donor electrode, and said second face adjacent to the body component of said mammalian subject, the architecture comprising a barrier layer substantially impervious to aqueous fluids; a counter electrode comprising the cathode operably coupled to said anode, wherein the operable coupling comprising the galvanic couple formed by the anode and the cathode generates an open circuit voltage of at least 2V; wherein the device does not comprise a reservoir containing a drug other than the therapeutic ions of the anode; and wherein the device is configured for self-powered lithium ion delivery from the lithium metal of the donor electrode to the body component.