Patent ID: 8862448

Claim:
A system for modeling a progression of a disease within a population, comprising: a plurality of point-of-care (POC) devices each comprising at least one programmable processor for executing at least one assay according to at least one assay protocol wherein the assay protocol comprises at least fluid transfer instructions to be performed by the POC devices; a central computing device operably in data communication with said plurality of POC devices, wherein the POC devices are positioned at distributed locations physically separate from the central computing device; a static database component comprising static data related to the disease and/or the population; a dynamic database component comprising dynamic data about the population and individual subjects, wherein the data in the dynamic database component comprises an indication of disease state of individuals in the population; and a computer modeling component that is configured to generate a model of the progression of the disease within the population based on the data in (1) the static database component and (2) the dynamic database component, thereby providing modeling results; wherein said at least one assay protocol when changed at the central computing device based at least on said modeling results, is sent from the central computing device to said plurality of POC devices for execution of a changed assay protocol by the devices without having to provide new devices to the distributed locations.