Patent ID: 7935797

Claim:
A monoclonal antibody which (a) binds to a CCR5 chemokine receptor on the surface of a CCR5+ CD4+ human cell; (b) inhibits fusion of HIV-1 JR-FL with a PM-1 cell; (c) does not inhibit fusion of HIV-1 BRU with a PM-1 cell; (d) does not activate an inflammatory response upon binding to the CCR5 chemokine receptor on the surface of the CCR5+ CD4+ cell; (e) competes with RANTES, MIP-1α and MIP-1β for binding to the CCR5 chemokine receptor on the surface of the CCR5+, CD4+ cell; and (f) inhibits binding of HIV-1 JR-FL gp120 to the CCR5+, CD4+ cell.