Patent ID: 7786167

Claim:
A method of treating a bacterial infection in a bovine comprising administering to the bovine a composition comprising a florfenicol ester and a pharmaceutically acceptable solvent wherein the florfenicol ester is selected from the group consisting of florfenicol acetate, florfenicol propionate, florfenicol butyrate, florfenicol pentanoate, florfenicol heptanoate, florfenicol octanoate, florfenicol nanoate, florfenicol decanoate, florfenicol undecanoate, and florfenicol dodecanoate; the bacterial infection is susceptible to florfenicol; the composition is administered as a single injection in an amount sufficient to treat the infection without requiring a second injection; and wherein administering a 40 mg/kg dose of the florfenicol ester provides a Cmax for the concentration of florfenicol in the bovine that is lower than the Cmax that would be obtained if the bovine was administered a comparative composition at a dose of 20 mg/kg, wherein the comparative composition contains 300 mg of florfenicol, 250 mg N-methyl-2-pyrrolidone, 150 mg propylene glycol, and sufficient polyethylene glycol to provide 1 mL of the comparative composition.