Patent ID: 7763657

Claim:
A compound of formula (I) or pharmaceutically acceptable salt thereof: wherein, X is NHCH 2 , CR 11 ═CR 12 , NH, CHR 11 CHR 12 , or C≡C, wherein R 11 and R 12 are independently hydrogen, halogen, C1-C5 alkyl, C1-C5 alkoxy, halo (C1-C5) alkyl, or phenyl; R 1 is C2-C5 alkenyl or C2-C5 alkynyl; R 2 is hydrogen, halogen, nitro, cyano, C1-C5 alkyl, C1-C5 alkoxy, halo (C1-C5) alkyl, C2-C5 alkenyl, C2-C5 alkynyl, carboxy, C1-C5 alkoxycarbonyl, C1-C5 alkylthio, phenyl, or phenyl (C1-C3) alkyl, wherein, each phenyl may be unsubstituted or substituted with one or more substituent selected from carboxy, C1-C5 alkyl, halogen, nitro, C2-C5 alkenyl, C1-C5 alkoxy, halo (C1-C5) alkyl, C1-C5 alkylcarbonyl, C1-C5 alkylthio, C1-C5 alkylsulfonyl, and C1-C5 alkoxycarbonyl; R 3 is hydrogen, C1-C5 alkyl, C1-C5 alkoxy, or halo (C1-C5) alkyl; R 4 , R 5 , R 6 , R 7 , and R 8 are independently hydrogen, carboxy, C1-C5 alkyl, nitro, C2-C5 alkenyl, C1-C5 alkoxy, C2-C5 alkynyl, halo (C1-C5) alkyl, C1-C5 alkylthio, C1-C5 alkylsulfonyl, C1-C5 alkylcarbonyl, C1-C5 alkoxycarbonyl, hydroxy, C2-C5 alkenyloxy, C1-C5 alkoxy (C1-C5) alkoxy, C1-C5 alkoxy (C1-C5) alkoxy (C1-C5) alkyl, C1-C3 alkylpiperazinyl, piperazinyl (C1-C5) alkoxy, piperidinyl (C1-C5) alkoxy, C1-C5 alkoxy (C1-C5) alkylamino, C1-C7 alkylamino, morpholinyl, morpholinyl (C1-C5) alkyloxy, tetrahydropyranyloxy, phenyl, or halogen, wherein, phenyl may be unsubstituted or substituted with one or more substituent selected from carboxy, C1-C5 alkyl, halogen, nitro, C2-C5 alkenyl, C1-C5 alkoxy, halo (C1-C5) alkyl, C1-C5 alkylcarbonyl, C1-C5 alkylthio, C1-C5 alkylsulfonyl, C1-C5 alkoxycarbonyl, or piperidinyloxy unsubstituted or substituted with C1-C5 alkoxycarbonyl; and R 9 and R 10 are independently hydrogen, —SO 2 R 13 , —SOR 13 , C1-C5 alkyl, C1-C5 alkoxy, halo (C1-C5) alkyl, C2-C5 alkenyl, C1-C5 alkoxycarbonyl, C1-C5 alkylthio, phenyl, or phenyl (C1-C3) alkyl, wherein, each phenyl may be unsubstituted or substituted with one or more substituent selected from carboxy, C1-C5 alkyl, halogen, nitro, C2-C5 alkenyl, C1-C5 alkoxy, halo (C1-C5) alkyl, C1-C5 alkylcarbonyl, C1-C5 alkylthio, C1-C5 alkylsulfonyl, and C1-C5 alkoxycarbonyl, and R 13 is hydrogen, amino, C1-C5 alkyl, C2-C5 alkenyl, C1-C5 alkoxy, halo (C1-C5) alkyl, trifluoromethyl, phenyl, or phenyl (C1-C3) alkyl.