Patent ID: 7507726

Claim:
A compound according to Formula (1): wherein: Y represents —C(O)— or a covalent bond; R represents arylene, heteroarylene or a covalent bond; Z represents —CH 2 —, —NR3—, —O—, —C(O)NR3—, —NR3C(O)— or —CH═CH— when R is a substituted arylene or a substituted heteroarylene, and represents —CH 2 — or —CH═CH— when R is a covalent bond; R3 is hydrogen, C 1-3 substituted alkyl, and (CH 2 ) 0-2 —C 3-6 substituted carbocycle; R1 is selected from the group consisting of: hydrogen, C 1-3 substituted alkyl, C 2-3 substituted alkenyl, C 2-3 substituted alkynyl, and (CH 2 ) 0-2 —C 3-6 substituted carbocycle; m is equal to 0 when Z =—NR3— or —CH 2 —; or m is equal to 0 or 1 when Z =—O—, —C(O)NR3— or —NR3C(O)—; or m is is an integer between 0 and 6 when Z =—CH═CH—; n is an integer equal to or greater than 2, appropriately chosen so that the number of atoms in the macrocyclic ring ranges from 13 to 16; or a pharmaceutically acceptable salt thereof.