Patent ID: 6872745

Claim:
A compound having the formula: wherein: W is CH; R a′ is an alkyl, cycloalkyl, or aryl group, where said alkyl, cycloalkyl, and aryl group is unsubstituted or substituted with one or more suitable substituents, provided that R a′ is not an amino-substituted alkyl group; R 4 and R 6 are each independently H or a lower alkyl group; R 5 is H or an alkyl group; R 7 is a moiety having the formula: wherein: R 8 and R 9 are each independently H or lower alkyl; p is an integer of from 1 to 5; A 1 is CH; when p is 1, 2, 3, 4, or 5, A 2 is C(R 10 )(R 11 ) where each R 10 and R 11 is independently H or a lower alkyl group; each A 3 present is independently C(R 10 )(R 11 ), where each R 10 and R 11 is independently H or a lower alkyl group; when p is 1, 2, 3, 4, or 5, A 4 is N(R 13 ), C(R 10 )(R 11 ), or O, where each R 10 , R 11 and R 12 is independently H or a lower alkyl group, each R 13 is H or an alkyl, aryl, or acyl group, and each R 14 is H or an alkyl or aryl group; and Z and Z 1 are each independently H, F, an alkyl, cycloalkyl, or aryl group, where the alkyl, cycloalkyl, or aryl group is unsubstituted or substituted with one or more suitable substituents —C(O)R 15 , —CO 2 R 15 , —CN, —C(O)NR 15 R 16 , —C(O)NR 15 OR 16 , —C(S)R 15 , —C(S)OR 15 , —C(S)NR 15 R 16 , —C(═NR 15 )R 16 , —C(═NR 15 )OR 16 , —NO 2 , —SOR 16 , —SO 2 R 15 , —SO 2 NR 15 R 16 , —SO 2 (NR 15 )(OR 16 ) —SONR 15 , —SO 3 R 15 , —PO(OR 15 ) 2 , —PO(OR 15 )(OR 16 ), —PO(NR 15 R 16 )(OR 17 ), —PO(NR 15 R 16 )(NR 17 R 18 ), —C(O)NR 15 NR 16 R 17 , —C(S)NR 15 NR 16 R 17 , where R 15 , R 16 , R 17 and R 18 are each independently H or an alkyl, cycloalkyl, aryl, acyl or thioacyl group, where the alkyl, cycloalkyl, aryl, acyl or thioacyl group is unsubstituted or substituted with one or more suitable substituents, or Z and Z 1 , together with the atoms to which they are bonded, form a cycloalkyl group, where Z and Z 1 are as defined above; or a prodrug, pharmaceutically acceptable salt, or pharmaceutically acceptable solvate of said compound.