Patent ID: 8445481

Claim:
A compound of the formula (II): or a pharmaceutically acceptable salt thereof, where R 0 is hydrogen, halogen, C 1-20 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, —CN, —NO 2 , —C(O)R′, —CO 2 R′, —C(O)NR′R″, —OR′, —OC(O)R′, —OC(O)NR′R″, —NR′C(O)R″, —NR′C(O)NR″R′″, —NR′R″, —NR′CO 2 R″, —NR′S(O) 2 R″, —SR′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, or C 6-10 aryl, where R 3 is hydrogen, halogen, C 1-20 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, —CN, —NO 2 , —C(O)R′, —CO 2 R′, —C(O)NR′R″, —NR′C(O)R″, —NR′C(O)NR″R′″, —NR′R″, —NR′CO 2 R″, —NR′S(O) 2 R″, or C 6-10 aryl, where R 4 , R 5 , and R 6 are each independently hydrogen, halogen, C 1-20 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, —CN, —NO 2 , —C(O)R′, —CO 2 R′, —C(O)NR′R″, or C 6-10 aryl, and R 5 and R 6 may, together with the atoms to which they are attached, form a 3- to 10-membered ring, where Z is carbon, nitrogen, oxygen, or sulfur, where n is 0-3, where R 7 can substitute any open valence of any ring within the structure, and R 7 is hydrogen, halogen, C 1-20 alkyl, C 2-8 alkenyl, —C 2-8 alkynyl, —CN, —NO 2 , —C(O)R′, —CO 2 R′, —C(O)NR′R″, —OR′, —OC(O)R′, —OC(O)NR′R″, —NR′C(O)R″, —NR′C(O)NR″R′″, —NR′R″, —NR′CO 2 R″, —NR′S(O) 2 R″, —SR′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, C 6-10 aryl, and where R′, R″ and R′″ are each independently selected from the group consisting of hydrogen, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 6-10 aryl, 5- to 10-membered heteroaryl, and 3- to 10-membered heterocyclyl; and R′ and R″ or R″ and R′″ may, together with the atoms to which they are attached, form a 3- to 10-membered ring.