Patent ID: 8188052

Claim:
A method for treating an ocular disease, wherein the disease is selected from the group consisting of dry eye, uveitis and phacoanaphylactic endophthalmitis, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of general formula (I): wherein: Ak is alkylene; R 1 is —NR 5 R 6 , in which R 5 and R 6 are each independently hydrogen or straight- or branched-chain alkyl comprising from one to six carbon atoms; or R 5 and R 6 , together with the nitrogen atom to which they are attached, form a saturated or unsaturated heterocyclic ring containing from four to six ring atoms, which ring may optionally contain another heteroatom selected from the group consisting of nitrogen, oxygen and sulfur and may be optionally substituted by from one to four groups which may be the same or different selected from alkyl, hydroxyl, amino, N-alkylamino and N,N-dialkylamino; R 2 is isobutyl; R 3 is (E)-2-butenyl-1 or n-butyl; R 4 is ethyl, 1-hydroxyethyl, isopropyl or n-propyl; or a pharmaceutically acceptable salt or solvate thereof.