Patent ID: 8563476

Claim:
A method for detecting an inflammatory disease in a subject, comprising: (a) detecting a level of expression of one or more inflammatory disease markers in a biological sample obtained from said subject; and (b) comparing the level of expression of said one or more inflammatory disease markers in said biological sample to a normal level of expression of said one or more inflammatory disease markers, wherein a higher than normal level of expression of one or more of said plurality of inflammatory disease markers in said biological sample is indicative of the presence of an inflammatory disease in said subject, wherein said normal levels of expression of said plurality of inflammatory disease markers is a predetermined value, and wherein said one or more inflammatory disease markers comprise one or more markers selected from the group consisting of CXCL9, CXCL10, CXCL11, CXCL13, CXCR3 and CXCR5 and wherein said one or more inflammatory disease markers further comprise one or more antibodies directed against, and/or one or more antigens derived from, inflammation-related microorganisms selected from the group consisting of Mycobacterium, Bacteroides, Brucella, Campylobacter, Escherichia coli, Saccharomyces cerevisiae, Klebsiella, Yersinia pseudotuberculosis, Clostridium, Enterococcus, Eubacterium, Listeria monocytogenes, Peptostreptococcus, Helicobacter, Haemophilus influenzae, Pseudomanas fluorescens, Salmonella, Chlamydia , human hepatitis virus and human rhinovirus.