Patent ID: 7790754

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof wherein Y is N; R 1 is R 2a is selected from (1) a group selected from R a , (2) (CH 2 ) n NR b C(O)R a , (3) (CH 2 ) n NR b SO 2 R d , (4) (CH 2 ) n NR b CO 2 R a , (5) (CH 2 ) k CO 2 R a , and (6) (CH 2 ) k C(O)NR b R c , R 2b is OH or a group selected from R 2a ; or R 2a and R 2b together with the carbon atom to which they are attached form a 3- to 7-membered carbocyclic ring optionally substituted with 1 to 4 groups independently selected from halogen, OR a , C 1-4 alkyl and C 1-4 haloalkyl; R 3a and R 3b are independently selected from hydrogen, C 1-4 alkyl, and C 1-4 haloalkyl; R 6 is optionally substituted 1,2,4-oxadiazolyl, and wherein said substituent is 1 to 3 groups independently selected from C 1-4 alkyl optionally substituted with 1 to 5 halogen atoms, OR a or OC(O)R a ; R 7 is selected from hydrogen and halogen; R 8 and R 9 are independently selected from (1) hydrogen, (2) C 1-8 alkyl optionally substituted with 1-5 groups independently selected from halogen, nitro, cyano, COR a , CO 2 R a , C(O)NR b R c , OR a , OC(O)R a , SR a , SO 2 R d , S(O)R d , NR b R c , NR b C(O)R a , NR b SO 2 R d , and NR b CO 2 R a , (3) C 3-8 cycloalkyl, (4) C 2-8 alkenyl optionally substituted with CO 2 R a , (5) halogen, (6) cyano, (7) nitro, (8) NR b R c , (9) NR b C(O)R a , (10) NR b CO 2 R a , (11) NR b C(O)NR b R c , (12) NR b C(O)NR b CO 2 R a , (13) NR b SO 2 R d , (14) CO 2 R a , (15) COR a , (16) C(O)NR b R c , (17) C(O)NHOR a , (18) C(═NOR a )R a , (19) C(═NOR a )NR b R c , (20) OR a , (21) OC(O)R a , (22) S(O) v R d , (23) SO 2 NR b R c , and (24) phenyl optionally substituted with 1 to 3 groups independently selected from halogen, nitro, cyano, OR a , SR a , C 1-4 alkyl and C 1-4 haloalkyl, and (25) OSO 2 R d ; R a is selected from (1) hydrogen, (2) C 1-7 alkyl optionally substituted with 1 to 5 halogen atoms, OH, SH, O—C 1-4 alkyl, or S—C 1-4 alkyl, (3) (CH 2 ) k -phenyl optionally substituted with 1 to 3 groups independently selected from halogen, cyano, nitro, OH, C 1-4 alkyloxy, C 3-6 cycloalkyl, C 1-4 alkyl and C 1-4 haloalkyl, and (4) C 3-6 cycloalkyl; R b and R c are independently selected from (1) hydrogen, (2) C 1-4 alkyl optionally substituted with 1 to 5 groups independently selected from halogen, amino, CO 2 R a , OR a , mono-C 1-4 alkylamino, and di-C 1-4 alkylamino, (3) (CH 2 ) k -phenyl optionally substituted with 1 to 3 groups selected from halogen, cyano, nitro, OR a , CO 2 R a , C 3-6 cycloalkyl, C 1-4 alkyl and C 1-4 haloalkyl, and (4) C 3-6 cycloalkyl; R d is selected from (1) C 1-4 alkyl, (2) C 1-4 haloalkyl, (3) C 1-4 alkyloxy, and (4) (CH 2 ) k -phenyl optionally substituted with 1 to 3 groups selected from halogen, cyano, nitro, OR a , CO 2 R a , C 3-6 cycloalkyl, C 1-4 alkyl and C 1-4 haloalkyl; R e is selected from hydrogen, C 1-4 alkyl, C 1-4 haloalkyl, C(O)H and C(O)C 1-4 alkyl; n is 1, 2, or 3; k is 0, 1, 2, 3, or 4; and v is 0, 1, or 2.