Patent ID: 7582665

Claim:
A compound represented by the general formula (III): wherein R 16 is a hydrogen atom, optionally substituted lower alkyl, carboxy, lower alkyloxycarbonyl, halogen atom, or optionally substituted aminocarbonyl; R 17 , R 18 , R 19 , R 20 , and R 21 are each independently a hydrogen atom, optionally substituted lower alkyl by one or more substituent(s) selected from substituent group B, cycloalkyl, optionally substituted alkyoxy by one or more substituent(s) selected from substituent group B, alkylthio, halogen atom, optionally substituted phenyl by one or more halogen atoms, optionally substituted heteroaryl by one or more halogen atoms, or optionally substituted nonaromatic heterocyclic group by one or more halogen atoms; substituent group B consists of hydroxy, alkyloxy, halogen atom, carboxy, lower alkyloxycarbonyl, aryloxycarbonyl, optionally substituted amino wherein the substituent is an alkyl, phenyl, non-aromatic heterocyclic group, or heteroaryl; or R 16 and R 17 taken together may form —CH 2 —, —CH 2 CH 2 —, —CH 2 CH 2 CH 2 —, —OCH 2 —, or —SCH 2 —; R 31 and R 32 are each independently a hydrogen atom, lower alkyl, halogen atom, halo(lower)alkyl, lower alkyloxy, halo(lower)alkyloxy, or hydroxy; W 3 is represented by the formula: wherein R 13 is a hydrogen atom, lower alkyl, lower alkyloxy, lower alkylthio, or halogen atom; R 14 and R 15 are each independently a hydrogen atom, or optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, or optionally substituted non-aromatic heterocyclic group, each substituted by one or more substituent(s) selected from substituent group A; substituent group A consists of a halogen atom, halo(lower)alkyl, optionally substituted amino, carboxy, lower alkylthio, lower alkylsilyl, or lower alkyloxy; R 24 is a hydrogen atom or lower alkyl; R 25 is lower alkyl, optionally substituted aryl, or optionally substituted non-aromatic heterocyclic group; A 3 is heteroaryl; or pharmaceutically acceptable salts thereof.