Patent ID: 7259258

Claim:
A compound of Formula I wherein X 1 and X 2 are each independently selected from the group consisting of NH—NH 2 and NH—N═CH—E—T—L—D, or X 1 is chloro and X 2 is selected from the group consisting of NH—NH 2 and NH—N═CH—E—T—L—D, or X 1 is selected from the group consisting of NH—NH 2 and NH—N=CH—E—T—L—D and X 2 is chloro, wherein E is a bond or an electron withdrawing group; T is selected from a bond, —C(O)—, —C(O)NH—, —NHC(O)—, an oxygen atom, a sulfur atom, NH, —S(O)—, —SO 2 —, or alkyl substituted with one or more substituents selected from the group consisting of dialkylamine, NO 2 , CN, SO 3 H, COOH, CHO, alkoxy, and halogen; L is a linker selected from the group consisting of a bond, —(CH 2 ) p —, —(CH 2 ) p —O—, —(CH 2 ) p —C(O)—, —(CH 2 ) p —C(O)NH—, —(CH 2 ) p —NHC(O)—, —(CH 2 ) p —S(O)—, —(CH 2 —CH 2 —O) p —, and —(CH 2 ) p —S(O) 2 —; and D is a biologically active polymer; Q is a solid surface; V is selected from a bond, NH, CO, NHCO, C(O)NH, (CH 2 ) p , sulfur, and oxygen, or a combination thereof; and p is an integer greater than or equal to zero.