Patent ID: 8247432

Claim:
A compound of formula (I) a stereochemically isomeric form thereof, or a pharmaceutically acceptable addition salt thereof, wherein n is 0; X represents —(CR 4 R 5 ) m — wherein m is 1; R 4 and R 5 are each independently from each other hydrogen or C 1-4 alkyl; R 1 is C 1-6 alkylcarbonyl optionally substituted with hydroxy; aminoC 1-6 alkylcarbonyl wherein the C 1-6 alkyl group is optionally substituted with C 3-6 cycloalkyl; mono- and di(C 1-4 alkyl)aminoC 1-6 alkylcarbonyl; aminocarbonyl substituted with aryl; C 1-6 alkylcarbonyloxyC 1-6 alkylcarbonyl; C 1-6 alkyloxycarbonylaminoC 1-6 alkylcarbonyl wherein the amino group is optionally substituted with C 1-4 alkyl; an amino acid bound via the carbonyl group; C 1-6 alkyl substituted with amino; or arylcarbonyl; R 2 is wherein m′ is an integer 1 to 2; R 6 is hydrogen or C 1-4 alkyl; R 7 is independently from each other halo; trifluoromethyl; C 1-6 alkyl; phenyl; aminocarbonyl; hydroxycarbonyl; or C 1-4 alkyloxycarbonyl; R 3 is a bivalent radical of formula wherein said (b-1) optionally can be substituted with one, two or three substituents each independently selected from halo, hydroxy, C 1-6 alkyl, C 1-6 alkyloxy, nitro, amino, cyano, trifluoromethyl, phenyl, or phenyl substituted with one or two subsitutents each independently selected from halo, hydroxy, cyano, C 1-6 alkyl, C 1-6 alkyloxy, nitro, cyano, and trifluoromethyl; aryl is phenyl, or phenyl substituted with amino, nitro or hydroxycarbonyl.