Patent ID: 7339031

Claim:
A modified bouganin protein having reduced propensity to elicit an immune response as compared to non-modified bouganin protein (SEQ ID NO: 1), wherein the amino acid sequence of the modified bouganin protein comprises: (SEQ ID NO: 11) YNTVSFNLGEAYEYPTFIQDLRNELAKGTPVCQLPVTLQTIADDKRFVLV DITTTSKKTVKVAIDVTDVYVVGYQDKWDGKDRAVFLDKVPTVATSKLFP GVTNRVTLTFDGSYQKLVNAAK X 1 DRK X 2 L X 3 LGV X 4 KLEFSIEAIHGKT INGQE X 5 AKFFLIVIQMVSEAARFKYIETEVVDRGLYGSFKPNFKVLNLE NNWGDISDAIHKSSPQCTTINPALQLISPSNDPWVVNKVSQISPDMGILK FKSSK wherein X 1 through X 5 can be any amino acid, provided that the amino acid sequence of the modified bouganin protein is not identical to the non-modified bouganin protein (SEQ ID NO: 1), wherein said modified bouganin protein inhibits protein synthesis on ribosomes.