Patent ID: 8796329

Claim:
A method for treating endometriosis comprising administering to a patient in need thereof a compound having the structure of formula (I) or a pharmaceutically acceptable salt thereof: wherein X is S or Se; W is O, S, or (R)(R), where each occurrence of R is independently H or C 1-2 alkyl; n is 0, 1 or an integer from 2 to 20; R 1 and R 2 are each independently C 1-10 alkyl; R 3 is H, C 1-10 alkyl, or C 0-6 alkyl-COOR 6 ; R 3′ is H, amino, cyano, halogen, aryl, aralkyl, heteroaryl, heteroaralkyl, carboxyl, C 1-10 alkyl, C 1-10 alkenyl, or C 1-10 alkynyl; R 4 is —OH, —H, —CH 3 , amino, —OC(O)C 1-10 aralkyl, —OC(O)C 1-10 alkyl, —OC(O)aryl, or a glutamine substituent; and R 5 is —OH, cyano, C 1-6 alkoxy, amino, O—C 1-10 alkyl, O-aralkyl, —OC(O)C 1-10 aralkyl, —OC(O)C 1-10 alkyl, —OC(O)aryl, or a glycine substituent; and R 6 is H or C 1-10 alkyl; or a compound having a structure of formula (III) or a pharmaceutically acceptable salt thereof wherein X is S or Se; W is O, S, or (R)(R), where each occurrence of R is independently H or a C 1-2 alkyl; Z is CH or N; R 1 and R 2 are independently C 1-10 alkyl, preferably R 1 and R 2 are independently selected from methyl, ethyl, propyl, and isopropyl; and R 5 is —OH, cyano, C 1-10 alkoxy, amino, O-aralkyl, O-aralkyl, —OC(O)C 1-10 aralkyl, —OC(O)C 1-10 alkyl, —OC(O)aryl, or a glycine substituent; R 6 is H or C 1-10 alkyl; R 7 is selected from halogen, —OH, C 0-6 alkyl-COOR 6 , C 1-6 alkyl, C 1-6 alkoxy, amino, amido, cyano, and nitro; m is an integer from 0 to 4.