Patent ID: 7468442

Claim:
A process for the preparation of crystalline Carvedilol Form-II using novel salts of Carvedilol, comprising the steps of: reacting 4-(2,3-epoxy propoxy) carbazole with 2-(2-methoxy phenoxy) ethyl amine in the molar ratio of 1:2.0 to 1:2.5 in an organic solvent selected from monochlorobenzene, ethylene glycol dimethyl ether (monoglyme) and mixtures thereof, adjusting the pH after completion of the reaction with at least one organic acid in the presence of water and at least one organic solvent and isolating the produced novel Carvedilol salts, treating the Carvedilol salts with at least one base in the presence of water and methylene chloride followed by separation of organic aqueous layers, and drying the organic layer followed by removal of the at least one organic solvent and crystallization of the residue in ethyl acetate.