Patent ID: 7470689

Claim:
A compound of the formula (I) wherein: A is CR 3 or N; B is CR 4 or N; D is CR 5 or N; E is CR 6 or N; where one of A, B, D, and E is N; R 1 is halogen; unsubstituted or at least monosubstituted C 1 -C 10 -alkyl, where the substituents are selected from the group consisting of: halogen, —CN, NO 2 , —OR 7 , —C(O)R 7 , —C(O)OR 7 , —O—C(O)R 7 , —NR 7 R 8 , —NHC(O)R 7 , —C(O)NR 7 R 8 , —NHC(S)R 7 , —C(S)NR 7 R 8 , —SR 7 , —S(O)R 7 , —SO 2 R 7 , —NHSO 2 R 7 , —SO 2 NR 7 R 8 , —O—SO 2 R 7 , —SO 2 —O—R 7 , aryl, heteroaryl, heterocyclyl, trifluoromethyl and trifluoromethoxy, and heterocyclyl, aryl and heteroaryl may in turn be at least monosubstituted by C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, halogen, trifluoromethyl, trifluoromethoxy or OH; unsubstituted or at least monosubstituted aryl or heteroaryl, where the substituents are selected from the group consisting of: halogen, —CN, NO 2 , —CH 2 —R 7 , —OR 7 , —C(O)R 7 , —C(O)OR 7 , —O—C(O)R 7 , —NR 7 R 8 , —NHC(O)R 7 , —C(O)NR 7 R 8 , —NHC(S)R 7 , —C(S)NR 7 R 8 , —SR 7 , —S(O)R 7 , —SO 2 R 7 , —NHSO 2 R 7 , —SO 2 NR 7 R 8 , —O—SO 2 R 7 , —SO 2 —O—R 7 , aryl, heteroaryl, trifluoromethyl and trifluoromethoxy, and aryl and heteroaryl may in turn be at least monosubstituted by C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, halogen, trifluoromethyl, trifluoromethoxy or OH; R 2 is hydrogen or C 1 -C 10 -alkyl; R 3 , R 4 , R 5 and R 6 are independently of one another selected from the group consisting of hydrogen, halogen, —CN, NO 2 , —CH 2 —R 8 , —OR 8 , —C(O)R 8 , —C(O)OR 8 , —O—C(O)R 8 , —NR 7 R 8 ; —NHC(O)R 8 , —C(O)NR 7 R 8 , —NHC(S)R 8 , —C(S)NR 7 R 8 , —SR 8 , —S(O)R 8 , —SO 2 R 8 , —NHSO 2 R 8 , —SO 2 NR 7 R 8 , —O—SO 2 R 8 , —SO 2 —O—R 8 , aryl, heteroaryl, heterocyclyl, trifluoromethyl and trifluoromethoxy, and heterocyclyl, aryl and heteroaryl may in turn be at least monosubstituted by C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, oxo, halogen, trifluoromethyl, trifluoromethoxy or OH; R 7 and R 8 are independently of one another: H; unsubstituted or at least monosubstituted C 1 -C 10 -alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -alkynyl, heterocyclyl, aryl or heteroaryl, where the substituents are selected from the group consisting of: heteroaryl, heterocyclyl, aryl, halogen, OH, oxo, C 1 -C 10 -alkoxy, (C 1 -C 10 -alkyl)thio-, COOH, —COO—(C 1 -C 6 -alkyl), —CONH 2 , trifluoromethyl, trifluoromethoxy; CN, NH 2 , (C 1 -C 10 -alkyl)amino- and di-(C 1 -C 10 -alkyl)amino-, and heterocyclyl, aryl and heteroaryl may in turn be at least monosubstituted by C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, oxo, trifluoromethyl, trifluoromethoxy, fluorine, chlorine or OH; heteroaryl is a 5 to 10-membered, aromatic, mono- or bicyclic heterocycle which comprises one or more heteroatoms selected from N, O and S; aryl is a 5 to 10-membered, aromatic, mono- or bicyclic system; heterocyclyl is a 5 to 10-membered, nonaromatic, mono- or bicyclic heterocycle which comprises one or more heteroatoms selected from N, O and S; or a physiologically tolerated salt thereof.