Patent ID: 6878734

Claim:
A compound of formula (I) wherein n is from 1 to 3, X and Y are independently ═N— or —N(R 5 )— wherein R 5 is selected from the group consisting of H, Me, Et, Pr, Bn, —OH and —CH 2 COOR 6 , wherein R 6 represents H, Me, Et, Pr or Bn; R 1 is H or a C 1 -C 15 saturated carbocylic ring optionally substituted with OMe, NMe 2 , CF 3 , Me, F, Cl, Br or I wherein up to three H atoms may optionally be replaced by halogen atoms; R 2 is selected from H, Me, Et, Pr and OH, each R 2 being independently selected from H, Me, Et, Pr and OH when n is greater than 1; R 3 is selected from the group consisting of H, Me, Et and Pr when n is 1; or, when n is greater than 1, each R 3 is independently selected from the group consisting of H, Me, Et and Pr, or two R 3 groups on neighbouring carbon atoms are linked to form a C 3 to C 6 carbocylic ring, or two R 3 groups are absent from neighbouring carbon atoms which are linked by a double bond; or R 2 and R 3 on the same carbon atom together represent an ═O group; R 4 is H or a C 3 to C 10 alicyclic ring wherein up to three H atoms may optionally be replaced by halogen atoms; Z is selected from the group consisting of: Q is a 6-membered aromatic carbocycle substituted with 1 or 2 V groups and optionally substituted with 1, 2 or 3 T groups; V is selected from the group consisting of —CO—NH—SO 2 —Ph, —SO 2 —NH—CO—Ph, —CH 2 OH, or a group of the formula —R 7 U, wherein U is selected from the group consisting of —COOH, tetrazolyl, —CONHOH and —SO 3 H; and R 7 is selected from the group consisting of a bond; C 1 to C 6 hydrocarbylene, optionally substituted by hydroxy, amino or acetamido; —O—(C 1 to C 3 alkylene)-; —SO 2 NR 8 —CHR 9 —; —CO—NR 8 —CHR 9 —, wherein R 8 and R 9 are independently selected from H and methyl; and —NH—(CO) c —CH 2 —, wherein c is 0 or 1.