Patent ID: 8486440

Claim:
An ocular drug delivery system comprising: a photocaged drug comprising a therapeutic agent that is rendered biologically inactive by being coupled to a protective ligand or caging group by a photocleavable bond; wherein said therapeutic agent is capable of being activated and/or released in response to a predetermined wavelength and/or intensity of light which breaks said photocleavable bond; wherein the therapeutic agent is selected from the group consisting of antibodies, aptamers, antisense DNA, antisense RNA, siRNA, antibiotics, antivirals, antifungals, steroids, non-steroidal anti-inflammatory agents, analgesics, drugs affecting intraocular pressure, statins, and neuroprotectants; wherein said photocaged drug is coupled to a superparamagnetic nanoparticle having a size from 50 to 200 nm and a magnetic core; and wherein the system is suitable for delivering the drug to an eye.