Patent ID: 8106074

Claim:
A method for treating opiate drug dependence, comprising administering an effective amount of at least one compound of formula (I): and/or its therapeutically acceptable salts, with pharmaceutically acceptable organic or mineral acids, to a patient in need thereof in which: u represents a hydrogen atom or a methyl radical, with the proviso that when u is a methyl radical then v and w represent a hydrogen atom; v represents a hydrogen atom, a chlorine atom or a methyl radical, with the proviso that when v is a methyl radical then u and w represent a hydrogen atom; w represents a hydrogen atom, a fluorine atom or a methyl radical, with the proviso that when w is a methyl radical then u and v represent a hydrogen atom; x represents a hydrogen atom or a fluorine atom; y represents a chlorine atom or a methyl radical; z represents a hydrogen atom, a fluorine atom, a chlorine atom or a methyl radical; A represents: a. a hydrogen atom, a fluorine atom or a chlorine atom; b. a straight or branched chain saturated aliphatic hydrocarbon radical having from 1 to 5 carbon atoms; c. a fluoroalkyl radical; d. a cyclopropyl, cyclobutyl or cyclopentyl radical; e. a 5-membered aromatic heterocyclic group, substituted or not, having 1, 2, 3 or 4 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, wherein at most one oxygen and/or one sulfur atom is present in the 5-membered heterocyclic group; f. an alkoxy (R 1 O—) or alkylthio (R 1 S—) group in which the R 1 radical represents: (1) an alkyl radical in C 1 -C 5 as defined above; (2) a monofluoromethyl or trifluoromethyl radical; (3) a cyclopropyl, cyclobutyl or cyclopentyl radical; (4) an amino group of formula (II): in which R 2 and R 3 , which may be identical or different, represent hydrogen, a straight or branched chain saturated aliphatic hydrocarbon radical having from 1 to 5 carbon atoms, a cyclopropyl group or a trifluoromethyl group; (5) a saturated cyclic amino group of formula (III): in which n is 1 or 2; or (6) an alkoxycarbonyl group.