Patent ID: 8357671

Claim:
A compound of formula Ia, Ib, Ic or Id: [R 9 -Sia-Sac-Y] n -Carrier Ia [R 9 -Sia-Sac-Y] n ˜Carrier Ib [R 5 -Sia-Sac-Y] n -Carrier Ic [R 5 -Sia-Sac-Y] n ˜Carrier Id wherein: R 5 and R 9 are independently each a hydrogen, hydroxyl, acetylamine, alkyl, alkylamide, cycloalkyl, heteroalkyl, cycloheteroalkyl, aryl, arylalkyl, arylamide or heteroaryl group that can be substituted with one to five alkyl, halo, sulfate or hydroxy groups and R5 and R9 are attached to different positions on the Sia; Sia is a sialic acid; Sac is a neutral saccharide; Y is a covalent bond to Carrier, a linker that can be attached to Carrier or an antigen that can bind to an antibody Carrier; the symbol ˜ is a non-covalent bond; n is an integer of 5 or more; and Carrier is a polymer, protein, antibody, antigen, multi-subunit protein, protein complex, glycan, lipid, liposome or solid support; and wherein at least one of R 5 or R 9 is an alkyl, alkylamide, cycloalkyl, heteroalkyl, cycloheteroalkyl, aryl, arylalkyl, arylamide or heteroaryl group that can be substituted with one to five alkyl, halo, or sulfate groups.