Patent ID: 8921355

Claim:
A compound of Formula (I) or a stereochemically isomeric form, N-oxide, salt, hydrate, or solvate thereof, wherein: R 1 is a bivalent chain selected from each R 3 is independently selected from the group comprising hydrogen, C 1-4 -alkyl and C 3-5 cycloalkyl; a is 3, 4, 5 or 6; each b is independently 1 or 2; c is 1 or 2; macrocycle A has 14 to 18 member atoms; each R 2 is independently hydrogen, halo or C 1-4 -alkoxy; R 4 and R 5 are hydrogen or R 4 and R 5 together form a double bond or a methylene group to form a fused cyclopropyl; R 6 is hydrogen or methyl; and R 7 is a C 3-7 cycloalkyl optionally substituted with halo.