Patent ID: 8632565

Claim:
A method of effecting wound closure of at least one tissue surface comprising: activating a compound having the formula D-B with a sufficient amount of an activating agent; and applying the activated compound to the at least one tissue surface; wherein D is a naphthalimide compound having the following formula: which is a mixture of stereoisomers, wherein n is an integer from 1 to 20; R is selected from the group consisting of CH 3 , C 4 H 9 , C 6 H 13 , (CH 2 ) 2 N(CH 3 ) 3 +CH 2 COOH, (CH) 2 CH 2 (CH 3 ) 2 COOH, and (CH) 2 CH 2 (CH 3 ) 2 COOCH 3 ; and R* is a bond between D and B; and B is a biomolecule selected from the group consisting of chitosan, protein, hydrolyzed protein, and carbohydrates.