Patent ID: 7186294

Claim:
A calcium phosphate cement with a desired setting time made by the process comprising: contacting a calcium phosphate composition comprising at least one calcium phosphate, wherein at least one calcium phosphate is Ca 4 (PO 4 ) 2 O, CaHPO 4 .2H 2 O, CaHPO 4 , Ca 8 H 2 (PO 4 ) 6 .5H 2 O, alpha-Ca 3 (PO 4 ) 2 , beta-Ca 3 (PO 4 ) 2 , Ca 2 P 2 O 7 , or Ca 2 H 2 P 2 O 8 , with a wetting liquid at a ratio less than about 10 g/ml to form a mixture; heating the mixture, to a temperature between about 50° C. to about 1000° C. that is selected such that a calcium phosphate cement made from the mixture has a desired setting time in the range of about 2.5 to about 52 minutes; forming calcium phosphate cement particles from the heated mixture; and contacting the calcium phosphate cement particles with a volume of setting liquid that is sufficient to form an injectable paste.