Patent ID: 7183111

Claim:
A composition, comprising: an immunomodulatory polynucleotide/microcarrier (IMP/MC) complex, said complex comprising a polynucleotide comprising an immunostimulatory sequence (ISS) linked to a nonbiodegradable microcarrier (MC), wherein the ISS comprises a sequence selected from the group consisting of 5′-TCGAAAA-3′, 5′-TCGCCCC-3′, 5′-TCGGGGG-3′, 5′-TCGTTTT-3′ and 5′-TCGTCGX 1 -3′, wherein X 1 is a nucleotide, and wherein the polynucleotide is less than about 200 nucleotides in length; and a pharmaceutically acceptable excipient.