Patent ID: 8796317

Claim:
A method of inhibiting glutathione S-transferase (GST) enzyme in the treatment of cancer, which method comprises: administering to a patient in need thereof an effective amount of a derivative of 7-nitro-2,1,3-benzoxadiazole of the formula: wherein R 1 is a linear, branched or cyclic alkyl with up to 12 carbon atoms, one hydrogen atom of R 1 being optionally substituted with one group selected from the group consisting of OR 2 , NO 2 , and NR 2 R 3 , wherein R 2 and R 3 are each independently selected from the group consisting of H, linear, branched or cyclic alkyl and alkenyl or alkynyl with up to 12 carbon atoms, and wherein said S—R 1 group is not a good leaving group.