Patent ID: 8771716

Claim:
A liquid pharmaceutical dosage form comprising: a) a first portion comprising ibuprofen and/or pharmaceutically acceptable salts thereof, wherein said ibuprofen is released from the dosage form in a substantially immediate manner upon contact of the dosage form with a dissolution medium; and b) a second portion comprising: i. a phenylephrine-ion exchange resin complex, said phenylephrine-ion exchange resin complex comprising phenylephrine complexed with a sulfonated co-polymer of styrene and divinylbenzene; ii. a first coating layer comprising a semi-permeable coating comprising a polymer selected from the group consisting of cellulose acetate, ethylcellulose, non-enteric polymethacrylates and copolymers and mixtures thereof, wherein said semi-permeable coating substantially covers said phenylephrine-ion exchange resin complex; and iii. a second coating layer comprising a protective coating, wherein said second coating layer covers said first coating layer, wherein said phenylephrine is released from the dosage form in a substantially sustained release manner.