Patent ID: 7268110

Claim:
A method for increasing platelet counts in a patient in need thereof, comprising administering to said patient a platelet-increasing effective amount of a composition comprising a parathyroid hormone (PTH) or a derivative thereof having a platelet-increasing activity similar to that of PTH, wherein said PTH or PTH derivative is selected from the group consisting of human PTH (1-34), human PTH (1-64), human PTH (35-84), bovine PTH (1-34), human PTH (1-84), human PTH (1-38) and human PTH (1-37), wherein said PTH or said PTH derivative optionally further comprises one or more of the following substitutions: (1) substitution of leucine or norleucine at the 8-position, (2) substitution of leucine or norleucine at the 18-position, and (3) substitution of tyrosine at the 34-position, and wherein said patient is a patient suffering from thrornbocytopenia purpura, selective suppression of megakaryocytes, a viral infection, aplastic anemia, osteomyelodysplasis syndrome, leukemia or multiple myeloma.