Patent ID: 7348429

Claim:
A process for preparing crystalline zaleplon characterized by a powder X-ray diffraction pattern having peaks at 7.9, 10.7, 12.5, 14.9, 16.9, 17.9, 21.3, 24.0, 25.2, 25.9, 27.0 and 27.5±0.2 degrees two-theta comprising the steps of: (a) forming a solution of zaleplon in at least one of methanol, ethanol, 2-propanol or acetonitrile; (b) contacting the solution with water to induce crystallization of zaleplon wherein crystallizaion is substantially complete in about one hour or less, and (c) separating crystalline zaleplon having peaks at 7.9, 10.7, 12.5, 14.9, 16.9, 17.9, 21.3, 24.0, 25.2, 25.9, 27.0 and 27.5±0.2 degrees two-theta from the organic solvent and water.