Patent ID: 8349327

Claim:
A method of treating muscular dystrophy in a mammal, comprising administering to a mammal in need of treatment for muscular dystrophy a therapeutically effective amount of a GDF-8 specific antibody or antigen binding fragment thereof, said antibody or fragment comprising: an antibody variable heavy (VH) domain having a first CDR comprising the amino acid sequence of SEQ ID NO:10 or SEQ ID NO:20, a second CDR comprising the amino acid sequence of SEQ ID NO:11 or SEQ ID NO:21, and a third CDR comprising the amino acid sequence of SEQ ID NO:12; and an antibody variable light (VL) domain having a first CDR comprising the amino acid sequence of SEQ ID NO:13, a second CDR comprising the amino acid sequence of SEQ ID NO:14, and a third CDR comprising the amino acid sequence of SEQ ID NO:15.