Patent ID: 8563551

Claim:
A method for treating a disease related to the glucocorticoid receptor selected from the group consisting of diabetes, obesity, enteritis, a chronic obstructive pulmonary disease, a connective tissue disease, a psychiatric disorder, Alzheimer's disease, a drug use disorder, hypertension, hypercalcemia, hyperinsulinemia, hyperlipidemia, a homeostasis-related disease causing an abnormality of a neuro-endocrine balance, and glaucoma, comprising administering a pharmacologically effective amount of a compound represented by the following formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient to a patient: wherein R 1 represents a hydrogen atom or a lower alkyl group; R 2 represents a hydrogen atom or a lower alkyl group; R 3 and R 4 are the same or different and represent a hydrogen atom or a lower alkyl group; R 5 represents a hydrogen atom or a lower alkyl group; R 6 represents a halogen atom, a lower alkyl group, a hydroxy group, a lower alkoxy group, a nitro group or a cyano group; X represents —CO—, —C(O)NR 8 —, —S(O)— or —S(O) 2 —; R 7 and/or R 8 are the same or different and represent a hydrogen atom, a lower alkyl group which optionally has a substituent, a lower alkenyl group which optionally has a substituent, a lower alkynyl group which optionally has a substituent, a lower cycloalkyl group which optionally has a substituent, an aryl group which optionally has a substituent, a heterocyclic group which optionally has a substituent, a lower alkoxy group which optionally has a substituent, a lower alkenyloxy group which optionally has a substituent, a lower alkynyloxy group which optionally has a substituent, a lower cycloalkyloxy group which optionally has a substituent, an aryloxy group which optionally has a substituent or a heterocyclic oxy group which optionally has a substituent; Y represents a lower alkylene group; Z represents a benzene ring or a heterocyclic ring; p represents 0, 1, 2 or 3, in the case where p is 2 or 3, each R 6 are the same or different.