Patent ID: 7456286

Claim:
A compound of formula (1): wherein: the dashed line joining A and C(R a ) is present and represents a bond and A is a —C(R b )═ group; R a and R b are each hydrogen; X is a —CH═ group; Y is a —C(R e )═ group; R e is hydrogen, —CN, —COR 1 , —CO 2 R 1 , —CONR 1a R 2a , —S(O) 2 NR 1a R 2a , —CONR 1a OR 2a or —C(O)N(R 3a )NR 1a R 2a ; R 1 is methyl, ethyl or trifluoromethyl R 1a and R 2a are, independently, a hydrogen atom or methyl group, or together with the nitrogen atom to which they are attached, represent —(CH 2 ) 4 — or —CH(CH 2 OH)(CH 2 ) 3 —; R 3a is a hydrogen atom or C 1-6 alkyl group; L is a —CH 2 —, —CH(CH 3 )—, —C(O)— or —CH 2 CH 2 — group; n is zero; Alk 1 is an optionally substituted aliphatic or heteroaliphatic chain; L 1 is a covalent bond; Cy 1 is phenyl, methylphenyl, methoxyphenyl, thienyl or indolyl; and Ar represents phenyl, pyridinyl, thienyl or benzothienyl, any of which groups may be optionally substituted by one or two substituents selected from halogen, cyano, C 1-6 alkyl, C 1-6 alkoxy and nitro; or a pharmaceutically acceptable salt or N-oxide thereof.