Patent ID: 7805194

Claim:
A method of adjusting therapy delivery in an implantable cardiac stimulation device, the method comprising: establishing a plurality of setting combinations for at least two variable parameters of the performance of the implantable cardiac stimulation device affecting delivery of therapy; evaluating at least one aspect of a patient's physiologic performance according to one or more measures under individual ones of the plurality of setting combinations wherein the plurality of setting combinations are selected such that at least one of the two variable parameters vary among the plurality of combinations; evaluating how changing one of the performance parameters affects how a second performance parameter affects the patient's physiologic performance according to the one or more measures; selecting a setting combination providing more optimal patient physiologic performance; and iterating the method with the plurality of setting combinations for the at least two variable parameters at a first graduation between settings of the variable parameters to determine a first more optimal setting combination; and reiterating the method with the plurality of setting combinations at a second graduation between settings of the variable parameters to determine a second more optimal setting combination.