Patent ID: 8361998

Claim:
A compound having the structure of Formula I: or a pharmaceutically acceptable salt thereof, wherein: each R 5 is independently selected from fluoro, nitrile, hydroxy, oxo, C 1-5 alkyl, C 3-5 cycloalkyl, C 1-5 alkoxy or C 1-5 alkoxyalkyl, wherein: any alkyl, cycloalkyl or alkoxy group is substituted by 0, 1 or 2 substituents independently selected from fluoro, nitrile or hydroxy, R 1 is selected from C 1-6 alkyl, C 3-6 cycloalkyl or C 1-6 alkoxyalkyl, wherein: any alkyl, cycloalkyl or alkoxy group is substituted by 0, 1 or 2 substituents independently selected from fluoro or nitrile, R 2 is selected from hydrogen or C 1-3 alkyl; R 3 is selected from C 1-6 alkyl, C 3-6 cycloalkyl or C 1-6 alkoxyalkyl, wherein: any alkyl or cycloalkyl group is substituted by 0, 1 or 2 substituents independently selected from fluoro, nitrile or hydroxy; each R 4 is independently selected from halo, nitrile, hydroxy, C 1-3 alkyl, C 1-3 alkoxy, C 1-3 alkoxyalkyl or C 1-3 alkylsulfide, wherein: any alkyl or alkoxy group is substituted by 0, 1, 2 or 3 substituents independently selected from halo, nitrile or hydroxy; m is selected from 1, 2 or 3; n is selected from 1 or 2; x is selected from 0, 1, 2, or 3; and y is selected from 0, 1, 2 or 3.