Patent ID: 7173151

Claim:
A compound of formula I: wherein Ring A is (C 3 â€“C 8 )-cycloalkanediyl or (C 3 â€“C 8 )-cycloalkenediyl, wherein one or more carbon atoms in said (C 3 â€“C 8 )-cycloalkane- and (C 3 â€“C 8 )-cycloalkenediyl groups may be replaced by oxygen atoms; R1, R2 are each independently H, (C 1 â€“C 6 )-alkyl, (C 3 â€“C 8 )-cycloalkyl or (C 6 â€“C 10 )-aryl; R3 is (C 3 â€“C 6 )-cycloalkyl or (C 1 â€“C 12 )-alkyl, each of which is optionally substituted by (C 6 â€“C 10 )-aryl, (C 5 â€“C 6 )-heteroaryl or (C 3 â€“C 6 )-cycloalkyl, and wherein said (C 6 â€“C 10 )-aryl, (C 5 â€“C 6 )-heteroaryl and (C 3 â€“C 6 )-cycloalkyl substituents are themselves optionally substituted by (C 1 â€“C 6 )-alkyl, (C 1 â€“C 6 )-alkoxy, Cl, Br, I, COâ€”(C 1 â€“C 6 )-alkyl, COâ€”O(C 1 â€“C 6 )-alkyl, COâ€”NH(C 1 â€“C 6 )-alkyl or COâ€”N((C 1 â€“C 6 )-alkyl) 2 ; X is (C 1 â€“C 6 )-alkanediyl, wherein one or more carbon atoms therein are optionally replaced by oxygen atoms; Y 1 is CO or a bond; Y 2 is NH or (C 1 â€“C 12 )-alkanediyl wherein one or more carbon atoms therein are optionally replaced by oxygen atoms; R4 is (C 1 â€“C 8 )-alkyl; R5 is H or (C 1 â€“C 6 )-alkyl; R6 is H; and pharmaceutically acceptable salts thereof.