Patent ID: 7244271

Claim:
A multi-layered ePTFE graft comprising: a first ePTFE tubular structure having a first internodal distance; a second ePTFE tubular structure having a second internodal distance different than said first internodal distance, said second ePTFE tubular structure being disposed about said first ePTFE tubular structure; and a self-sealing layer interposed between said first and second ePTFE tubular structures, wherein said self-sealing layer comprises a gel selected from the group consisting of gelatin, collagen, albumin, casein, algin, carboxymethyl cellulose, carageenan, furcellan, agarose, guar, locus bean gum, gum arabic, hydroxyethyl cellulose, hydroxypropyl cellulose, methyl cellulose, hydroxyalkylmethyl cellulose, pectin, partially deacetylated chitosan, starch and starch derivatives, amylose, amylopectin, xanthan, polylysine, hyaluronic acid, and its derivatives, heparin, their salts, and mixtures thereof, and wherein said self-sealing layer interposed between said first and second ePTFE tubular structures further comprises an elastomeric polymer layer comprising an elastomeric polymer component selected from the group consisting of thermoplastic elastomers, silicones, silicone rubbers, synthetic rubbers, polyurethanes, polyethers, polyesters, polyamides, fluoropolymers selected from the group consisting of fluorinated ethylene propylene copolymer and polyfluorinated alkanoates, and combinations thereof.