Patent ID: 8100528

Claim:
A method of forming a surface modified medical device, the method comprising: providing a medical device having at least one group providing interactive functionality on at least one surface of the medical device, wherein the medical device comprises hydrogel materials; providing a surface modifying agent comprising an interactive segmented block copolymer having a structure selected from the following structural formulas I-III: R1-[(A) m]p -[(B) n]q -X (I), R1-[(A) m]p -[(B) n]q -R2, and (II) R1-[(B) n]q -[(A) m]p -R2-[(A) m]p -[(B) n]q -R1 (III) wherein R1 is a reactive residue of a moiety capable of acting as an initiator for Atom Transfer Radical Polymerization, a radical forming residue of a Reversible addition-fragmentation chain transfer polymerization agent or a free radical initiator; R2 is a thio carbonyl thio group, thio carbonyl fragment of a chain transfer agent or a derivatized reaction product; A is a chemical binding unit block, B is a hydrophilic unit block, m is 1 to 10,000, n is 1 to 10,000, p and q are natural numbers, and X is a halogen capping group of an initiator for Atom Transfer Radical Polymerization or a derivatized reaction product contacting the at least one surface having interactive functionality of the medical device with the surface modifying agent, and; subjecting the device surface and surface modifying agent to reaction conditions suitable for forming a chemical interaction selected from the group consisting of electrostatic or complexation interaction between the device surface and the surface modifying agent to form a surface modified medical device.