Patent ID: 7919098

Claim:
A method for treating a neoplasm which expresses ErbB-3 in a mammal, which method comprises administering to a mammal, to which such treatment is needed or desirable, an effective amount of an ErbB-3 protein or a nucleic acid that encodes and expresses said ErbB-3 protein, whereby an immune response is generated against said neoplasm, wherein the ErbB-3 protein is a fragment of the extracellular domain of ErbB3 and comprises: (a) the amino acid sequence set forth in SEQ ID NO:3; or (b) amino acid residues 24-81 of the amino acid sequence set forth in SEQ ID NO:14; or (c) amino acid residues 2-139 of the amino acid sequence set forth in SEQ ID NO:16, wherein the ErbB-3 protein is not the entire extracellular domain of ErbB3.