Patent ID: 7323296

Claim:
A method for diagnosing whether a subject is insulin sensitive (IS), insulin resistant (IR) or diabetic (NIDDM) comprising: a) administering 75 grams of glucose to the subject; b) obtaining samples from the subject at 0, 60 and 120 min after glucose administration; c) performing tests on the samples to obtain sample readings wherein the sample readings are concentrations of glucose, insulin, triglyceride (TG) and high density lipoprotein (HDL); d) calculating TG/HDL ratio from the sample readings for TG and HDL; e) comparing sample readings for glucose and insulin concentrations and TG/HDL ratio to readings from reference populations wherein i) a first reference population that has been diagnosed as IS has a glucose concentration at 0 min that is less than 126 mg/dl, at 60 min that is less than or equal to 121 mg/dl and at 120 min is less than or equal to 100 mg/dl; an insulin concentration at 0 min that is less than or equal to 19 μIU/ml, at 60 min that is less than 50 μIU/ml or at 120 min that is less than 40 μIU/ml; and a TG/HDL ratio that is less than 2; ii) a second reference population that has been diagnosed as IR has a glucose concentration at 0 min that is less than 126 mg/dl, at 60 min that is equal to or greater than 170 mg/dl and at 120 min that is equal to or greater than 127 and less than 200 mg/dl and an insulin concentration at 0 min that is less than or equal to 55 μIU/ml and at 60 min or at 120 min that is greater than 60 μIU/ml; and iii) a third reference population that has been diagnosed as NIDDM has a glucose concentration at 0 min that is equal to or greater than 126 mg/dl or at 120 min that is greater than 200 mg/dl; and f) diagnosing whether the subject is IS, IR or NIDDM based on the comparison.