Patent ID: 8492395

Claim:
A compound having a structure of formula (V): or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: R 15 is —(CH 2 ) n NHR j , wherein R j is: hydrogen; (C 1 -C 6 )alkyl, optionally substituted with one or more halo; —(CH 2 ) n -(6 to 10 membered aryl); —C(O)—(CH 2 ) n -(6 to 10 membered aryl) or —C(O)—(CH 2 ) n -(6 to 10 membered heteroaryl), wherein the aryl or heteroaryl is optionally substituted with one or more of: halo; —SCF 3 ; (C 1 -C 6 )alkyl, itself optionally substituted with one or more halo; or (C 1 -C 6 )alkoxy, itself optionally substituted with one or more halo; —C(O)—(C 1 -C 8 )alkyl, wherein the alkyl is optionally substituted with one or more halo; —C(O)—(CH 2 ) n —(C 3 -C 10 -cycloalkyl); —C(O)—(CH 2 ) n —NR k R l , wherein R k and R l are each independently: hydrogen; (C 1 -C 6 )alkyl, optionally substituted with one or more halo; (C 1 -C 6 )alkoxy, optionally substituted with one or more halo; or 6 to 10 membered aryl, optionally substituted with one or more of: halo; (C 1 -C 6 )alkyl, itself optionally substituted with one or more halo; or (C 1 -C 6 )alkoxy, itself optionally substituted with one or more halo; —C(O)—(CH 2 ) n —O—(C 1 -C 6 )alkyl; or —C(O)—(CH 2 ) n —O—(CH 2 ) n -(6 to 10 membered aryl); R 16 is: hydrogen; —(CH 2 ) n OH; phenyl; —O—(C 1 -C 6 ) alkyl; or (C 1 -C 6 )alkyl, optionally substituted with one or more halo; R 17 is: hydrogen: or (C 1 -C 6 )alkyl, optionally substituted with one or more halo; and n is 0, 1, or 2.