Patent ID: 6946489

Claim:
A compound of the formula I in which: R 1 is: phenyl or naphthyl, which is substituted by —C(═NH)NH 2 , that is optionally monosubstituted by —COA, —CO[C(R 7 ) 2 [ n -Ar′, —COOA, —OR 7 , —OCOA, —OCO—[C(R 7 ) 2 [ n -Ar′, —OH, an amino protective group, —NHC(═NH)—NH 2 , —CON═C(NH 2 ) 2 , and which is optionally substituted by -A, —OR 5 , —N(R 5 ) 2 , —NO 2 , —CN, —Hal, —NR 5 COA, —NR 5 COAr′, —NR 5 SO 2 A, —NR 5 SO 2 Ar′, —COOR 5 , —CON(R 5 ) 2 , —COR 7 , —COAr′ or S(O) n A; R 2 is: —S(O) n A, —CF 3 , —COOR 7 , or —OA; R 3 , R 4 are: independently of one another —H, -A, —OR 5 , —N(R 5 ) 2 , —NO 2 , —CN, —Hal, —NR 5 COA, —NR 5 COAr′, —NR 5 SO 2 A, —NR 5 SO 2 Ar′, —COOR 5 , —CON(R 5 ) 2 , —CONR 5 Ar′, —COR 7 , —COAr′, or —S(O) n A; R 5 , R 6 are: independently of one another —H, -A, —[C(R 7 R 8 )] n Ar′ or —[C(R 7 R 8 )] n Het; R 7 , R 8 are: independently of one another —H or -A; W is: —[C(R 5 R 6 )] m CONR 5 [C(R 5 R 6 )] 1 —, or —OC(R 5 R 6 )CONR 5 [C(R 5 R 6 )] l ; A is: alkyl having 1 to 20 C atoms, in which one or two CH 2 groups are optionally and independently replaced by O or S atoms or by —CH═CH—groups and wherein 1 to 7 H atoms are optionally replaced by —F; Ar is: phenyl or naphthyl, which is unsubstituted or mono-, di- or trisubstituted by -A, -Ar′-, -Het, —OR 5 , —N(R 5 ) 2 , —NO 2 , —CN, -Hal, —NR 5 COA, —NR 5 COAr, —NR 5 SO 2 A, —NR 5 SO 2 Ar′, —COOR 5 , —CON(R 5 ) 2 , —CONR 5 Ar′, —COR 7 , —COAr′, —SO 2 NR 5 , —S(O) n Ar′ or —S(O) n A; Ar′ is: phenyl or naphthyl, which is unsubstituted or mono-, di- or trisubstituted by -A, —OR 7 , —N(R 7 ) 2 , —NO 2 , —CN, -Hal, —NR 7 COA, —NR 7 SO 2 A, —COOR 7 , —CON(R 7 ) 2 , —COR 7 , —SO 2 NR 7 or —S(O) n A; Het is: a mono- or binuclear saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, bonded via N or C, which is unsubstituted or mono-, di- or trisubstituted by -A, —OR 7 , —N(R 7 ) 2 , —NO 2 , CN, -Hal, —NR 7 COA, —NR 7 SO 2 A, —COOR 7 , —CON(R 7 ) 2 , —COR 7 , SO 2 NR 7 , —S(O) n A and/or carbonyl oxygen; Hal is: —F, —Cl, —Br or —l; l is: 0 or 1; m is: 1, 2 or 3; and n is: 0,1 or 2; or a pharmaceutically acceptable salt or solvate thereof.