Patent ID: 8367686

Claim:
A compound of formula (I): in free or salt form, wherein: A 1 is N; R 1 is C 1-6 alkyl, C 1-6 cycloalkyl, or aryl optionally substituted with alkyl, haloalkyl, alkyloxy, or halo group; R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are independently hydrogen, halo, C 1-4 alkyl, C 1-4 alkyloxy, or trifluoromethyl; or R 5 and R 6 , together with carbon atoms to which they are attached, form a 5 or 6 member hetcyclic ring; Y is —NHCO—, —CONH—, —NHSO 2 —, —NHCONH—, or —NHCH 2 —; D is a 5 or 6 member aryl, hetaryl, or hetcyclic ring having at least one N, S, or O ring atom, or a C ring atom forming an oxo (C═O) moiety; provided that D is not a substituted phenyl group if A 1 =N and R 2 ═R 3 ═R 4 ═R 5 ═R 6 ═H and R 7 ═CH 3 and Y═NHCO; and R 8 is C 3-7 cycloalkyl, aryl, hetaryl, aryl(C 1-4 alkyl)-, or hetcyclyl(C 0-4 alkyl)-, optionally substituted with C 1-6 alkyl.