Patent ID: 8410075

Claim:
A compound having Formula IV: or a pharmaceutically acceptable salt thereof, wherein: each of R 1 -R 4 is independently hydrogen, hydroxy; OC(═O)R 11 ,OR 12 or one of R 1 and R 2 and one of R 3 and R 4 together form a double bond or a —OC(═X 3 )O— group, wherein X 3 is S or O; each of R 5 and R 6 is independently hydrogen, alkyl, CH 2 OR 13 or C(═O)—CR′R″H; wherein R′ is alkyl, alkoxy, or trifluoroacetamido; R″ is phenyl or phenylmethyl; R 7 is hydrogen, halo, alkyl, amine, alkylamine, dialkylamine, dialkylamine N-oxide, trifluoromethyl or trifluoromethyl amine; each of R 8 and R 9 is independently alkyl, aryl, aralkyl, alkoxyalkyl, hydroxyalkyl, or R 8 and R 9 together with the nitrogen to which they are attached form a heterocyclic ring comprising one, two or three heteroatoms selected from the group consisting of N, O, S, SO and SO 2 , said heterocycle having 1-4 substituents selected from the group consisting of hydroxy, alkoxy, halogen or hydroxyalkyl; R 10 is O or is absent, provided that R 10 is O when R 7 is not dialkylamine N-oxide; R 11 is hydrogen, acyl, alkylcarboxy, alkyl; R 12 is hydrogen, acyl or a group of the formula: wherein X 1 and X 2 are independently O or S; R 4 is optionally substituted phenyl, optionally substituted benzyl or optionally substituted naphthyl; R 5 is alkyl or alkenyl; and R 13 is hydrogen, acyl, alkylcarboxy, alkyl, aralkyl, a monosaccharide, or a group of the formula: wherein X 1 and X 2 are independently O or S; R 6 is optionally substituted phenyl, optionally substituted benzyl or optionally substituted naphthyl; R 7 is alkyl or alkenyl.