Patent ID: 7943617

Claim:
A compound of Formula (I): or an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, wherein: Q is a bond, L is —N— and M is —C═; R 1 is selected from the group consisting of halo, halo-C 1 -C 3 alkyl and optionally substituted C 1-3 alkyl; R 2 is selected from the group consisting of halo, halo-C 1 -C 3 alkyl, optionally substituted C 1 - 3 alkyl, C 1 -C 3 alkoxy and —[C(O)] 2 NR 7 R 8 wherein each of R 7 and R 8 is independently an optionally substituted C 1 -C 3 alkyl, and further wherein R 7 and R 8 can be taken together with the atoms to which they are attached to form an optionally substituted 5-6 membered ring; R 3 and R 4 are each hydrogen; ring A is selected from the group consisting of phenyl, indole and pyrrolo[2, 3-b] pyridine; m is 1 or 2; and n is 1 or 3; wherein the optional substituents for C 1 -C 6 alkyl groups are 1-4 groups selected from halo nitro, cyano, hydroxy, alkoxy, haloalkoxy, —O-aryl, —O-heterocyclo, —O-alkylene-aryl, —O-haloalkyl, alkylthio, carboxy, alkoxycarbonyl, alkylcarbonyloxy, carbamoyl, substituted carbamoyl, carbamate, substituted carbamate, urea, substituted urea, amidinyl, substituted amindinyl, aryl, heterocycle, cycloalkyl, —NR c R d , —OC(═O)NR c R d , —C(═O)NR c R d , —NR e C(═O)NR c R d , —NR e C(O) 2 —NR c R d ,—N(R e )S(O) 2 NR c R d , —N(R e )P(O) 2 NR c R d , (wherein each of R c and R d is independently selected from hydrogen, alkyl, and heterocyclo, and R e is hydrogen, alky, or phenyl); and —SR f , —S(═O)R g ,—S(O) 2 R g , —NR e S(O) 2—R g ,—P(O) 2 —R g ,—NR e P(O) 2 —R g , —NR e C(═O)R f , —NR e C(O) 2 R f , —OC(═O)R f , —OC(═O)OR f , —C(═O)OR f or —C(═O)R f (wherein R e is defined as immediately above, R f hydrogen, alkyl, aryl or heterocyclo, and R g is alkyl, aryl, or heterocyclo); in the aforementioned substituents, in each instance, the alkyl, aryl, heterocyclo or cycloalkyl groups (R c , R d , R e , R f , and R g ) in turn an be optionally substituted with one to four, preferably one to three further groups, selected from R k , —O—R k , cyano, nitro, haloalkyl, haloalkoxy, halo, —NR k R x , —OC(═O)NR k R x , —C(═O)NR k R x , —NR k C(═O)R x , —SR k , —S(═O)R y , —S(O) 2 R y , —OC(═O)R k , —C(═O)OR k , —C(═O)R k , phenyl, benzyl, phenyloxy, or benzyloxy, or a lower alkyl substituted with one to two of —O—R k , cyano, nitro, haloalkyl, haloalkoxy, halo, —NR k R x , —OC(═O)NR k R x , —C(═O)NR k R x , —NR k C(═O)R x , —SR k , —S(═O)R y , —S(O) 2 R y , —OC(═O)R k , —C(═O)OR k , —C(═O)R k , phenyl, benzyl, phenyloxy, or benzyloxy, wherein R k and R x are selected from hydrogen, lower alkyl, hydroxy(lower alkyl), halo(lower alkyl), cyano(lower alkyl), and amino(lower alkyl), and R y is lower alkyl; and wherein the optional substituents for an optionally substituted 5-6 membered ring are 1-4 groups selected from alkyl; substituted alkyl; the substituents recited above for substituted alkyl groups, and additionally, in the case of a 5-6 membered heterocyclo, oxo (═O).