Patent ID: 7220776

Claim:
A process for the synthesis of perindopril of formula (I): and pharmaceutically acceptable salts thereof, wherein a compound of formula (II): is reacted with a compound of formula (III): wherein X 1 and X 2 , which may be identical or different, each represent a leaving group, to yield a compound of formula (IV): which is reacted with a compound of formula (V): wherein R represents hydrogen, benzyl or linear or branched (C 1 -C 6 )alkyl, or an addition salt thereof with a mineral or organic acid, to yield, after isolation, a compound of formula (VI): which is hydrogenated in the presence of a catalyst, under a hydrogen pressure of from 1 to 30 bars, to yield, after deprotection of the acid function where necessary, perindopril of formula (I) which is converted, if desired, to a pharmaceutically acceptable salt.