Patent ID: 7994139

Claim:
A compound of formula I: wherein; B represents a 5, 6, 7 or 8 membered carbocyclic or heterocyclic ring comprising one or more double bonds, wherein B is optionally substituted with one or more oxo, thioxo, NR c R d , F, Cl, Br, I, OR z , SR z , alkyl, C≡N, C≡C—R, N 3 or SO 2 R′; wherein: R is H, alkyl or aryl; R′ is OH, NH 2 or alkyl; R 1 is H, NR a R b , Cl, F, OR a , SR a , NHCOR a , NHSO 2 R a , NHCONHR a , CN, alkyl, aryl, ONR a R b , or NR a C(O)OR b ; R 2 is a nucleoside sugar group; W 3 is absent, alkyl, or H; R a and R b are independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, heterocyclic, aryl, substituted aryl, acyl, substituted acyl, SO 2 -alkyl, amino, substituted amino, and NO; or R a and R b together with the nitrogen to which they are attached form a pyrrolidino, piperidino, piperazino, azetidino, morpholino, or thiomorpholino ring; R c and R d are independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, acyl, substituted acyl and SO 2 -alkyl; or R c and R d together with the nitrogen to which they are attached form a pyrrolidino, piperidino, piperazino, azetidino, morpholino, or thiomorpholino ring; and each R z is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, acyl and substituted acyl; or a pharmaceutically acceptable salt or prodrug thereof.