Patent ID: 7816379

Claim:
A method for preparing an oxazolidinone derivative of Formula (I): or a pharmaceutically acceptable salt thereof wherein, R 1 and R′ 1 are independently hydrogen or fluorine; R 2 is —NR 5 R 6 , —OR 7 , fluorine, alkylphosphate, monophosphate or a metal salt of monophosphate; R 5 and R 6 are independently hydrogen or C 1-4 alkyl; R 7 is hydrogen, C 1-3 alkyl or acylated amino acid, wherein the amino acid is alanine, glycine, proline, isoleucine, leucine, phenylalanine, β-alanine or valine; R 3 is hydrogen, C 1-4 alkyl group that is unsubstituted, or substituted with cyano, —(CH 2 ) m —OR 7 or ketone; and m is 0, 1, 2, 3, or 4; the method comprises the steps of: reacting a compound of Formula (III) wherein Y is halogen: with a tin compound to provide a compound of Formula (IV) wherein Z is C 1-4 alkyl: reacting the compound of Formula (IV) with a compound of Formula (VI): under conditions selected to give a compound of Formula (V): optionally reacting the compound of Formula (V) under conditions selected to give the compound of Formula (I).