Patent ID: 8501968

Claim:
A method of treating an individual affected by cancer comprising administering to said affected individual a therapeutically effective amount of a compound of general formula I wherein R 1 is hydrogen or unsubstituted C 1 -C 12 alkoxy; R 2 , R 3 , R 42 , R 44 , R 45 , R 46 , and R 47 are hydrogen; R 41 and R 43 are hydrogen or unsubstituted C 1 -C 12 alkyl; R 48 is selected from hydrogen, substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl and substituted or unsubstituted C 2 -C 12 alkynyl; each R 5 , R 6 , and R 7 are independently selected from hydrogen, COR a , COOR a , substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl and substituted or unsubstituted C 2 -C 12 alkynyl, or R 5 and R 48 together with the corresponding N atom and C atom to which they are attached may form a substituted or unsubstituted heterocyclic group; R a is selected from hydrogen, substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl, substituted or unsubstituted C 2 -C 12 alkynyl, substituted or unsubstituted aryl and substituted or unsubstituted heterocyclic group; and each dotted line represent an optional additional bond; or a tautomer or stereoisomer thereof.