Patent ID: 8828069

Claim:
A medical device having a layer formed according to a method comprising: providing a composition comprising a hydroxyl polymer; providing a medical device comprising a coating; forming a layer of the composition on the coating; attaching a spacer to the layer to generate dangling functional-group-terminated spacer chains; and conjugating a bioactive agent to the spacer via the functional group; wherein the hydroxyl polymer has a structure of where: P is H, CH 3 , absence, ethylene vinyl alcohol, or a polymeric, oligomeric or monomeric unit; R 1 and R 2 are independently H, CH 3 , or CH 3 CH 2 ; R 3 is H, CH 3 , CH 3 CH 2 , or P; and n is an integer ranging from 1 to about 1,000,000; wherein the method further comprises curing the composition layer thereby grafting the hydroxyl polymer to the coating.