Patent ID: 8012687

Claim:
A method for detecting the presence of an isolated genomic nucleic acid molecule, said nucleic acid molecule is a fragment of human chromosome 19, said nucleic acid molecule, selected from the group consisting of: (i) a nucleic acid molecule consisting of a nucleic acid sequence which has at least 99% identity to the nucleic acid molecule of SEQ ID NO:3, which encodes a polypeptide having the amino acid sequence of SEQ ID NO:1, wherein said polypeptide inhibits the action of insulin; (ii) a fragment of the nucleic acid molecule of (i) said fragment comprising at least nucleotides 19611-20633 of SEQ ID NO:3, and which encodes a polypeptide having the amino acid sequence of SEQ ID NO:1, wherein said polypeptide inhibits the action of insulin and; (iii) a full complement of (i) or (ii) comprising: (a) contacting the sample with a polynucleotide probe comprising at least 20 contiguous nucleotides of the polynucleotide of (i) or its complement that hybridizes to said nucleic acid molecule under stringent conditions and (b) determining whether the polynucleotide probe binds to said nucleic acid molecule in the sample.