Patent ID: 7393868

Claim:
A compound of Formula I: where: A is selected from the group consisting of R is H, halo, —COOH, or —CH 2 COOH; R 1 is phenyl optionally substituted with a first substituent selected from the group consisting of halo, cyano, C 1 -C 4 acyl, —COOH, —NHR 3 , C 1 -C 2 alkyl substituted with —NHCH 3 , —N(SO 2 (C 1 -C 3 alkyl)) 2 , —COOH, —CONH 2 , cyano, hydroxy, or tetrazol-5-yl, —OCH 2 COOH, —SCH 2 COOH, —C(O)CH 2 CH 2 COOH, —SO 2 NH 2 , tetrazol-5-yl, and 1,2,4-triazol-1-yl; optionally further substituted with a second substituent selected from the group consisting of: halo, trifluoromethyl, cyano, nitro, C 1 -C 4 alkoxy, hydroxy, C 1 -C 4 alkyl, C 1 -C 4 alkylthio, —NHCH 2 CN, —OCH 2 CN, —NHSO 2 CH(CH 3 ) 2 , and —C(O)NHR 4 ; optionally further substituted with a third substituent selected from the group consisting of halo and cyano; optionally further substituted with a fourth substituent selected from the group consisting of halo; R 2 is C 1 -C 4 alkyl or dimethylamino; R 3 is —SO 2 (C 1 -C 3 alkyl), C 1 -C 4 acyl, C 1 -C 4 alkyl, or hydrogen; R 4 is hydrogen, C 1 -C 4 alkyl, or —SO 2 (C 1 -C 4 alkyl); or a pharmaceutically acceptable salt thereof, provided that when A is and R 2 is isopropyl, then R 1 is not 2-ethoxy-4-carboxyphenyl.