Patent ID: 8076331

Claim:
A compound of Formula I: wherein: R 1 is H, —OR 7 , —SR 7 , —SOR 7 , —SO 2 R 7 , —NR 9 R 10 , halogen, C 1-4 alkyl, C 4-10 cycloalkyl, C 1-4 haloalkyl, C 6-12 aryl, 5-10 membered heteroaryl, or 3-10 membered heterocycloalkyl, wherein each of said C 1-4 alkyl, C 4-10 cycloalkyl, C 1-4 haloalkyl, C 6-12 aryl, 5-10 membered heteroaryl, and 3-10 membered heterocycloalkyl is optionally substituted by 1, 2, or 3 R 11 ; R 2 and R 3 are independently H or C 1-4 alkyl; or R 2 and R 3 are taken together to form a C 4-10 cycloalkyl or phenyl, wherein each of said C 4-10 cycloalkyl and phenyl is optionally substituted by 1, 2, or 3 halogen or C 1-4 alkyl; each R 4 is independently H or C 1-4 alkyl or OH; each R 5 is independently C 1-4 alkyl, or hydroxyalkyl; each R 6 is independently halogen, C 1-4 haloalkyl, —OH, C 1-4 alkyl, —O—C 1-4 alkyl, —NR 9 R 10 , or CN; R 7 is C 1-4 alkyl, C4-10 cycloalkyl, 5-10 membered heteroaryl, C 6-12 aryl, C 6-12 arylC 1-6 alkyl, 5-10 membered heteroarylalkyl, or a 3-10 membered heterocycloalkyl; R 9 and R 10 are independently H, C 1-4 alkyl, or arylalkyl; each R 11 is halogen, —OH, —OC 1-4 alkyl, C 1-4 alkyl, C 1-4 haloalkyl, or —CN; X is O or S; m is 2, 3, 4, 5, or 6; n is 0, 1, or 2; y is 0, 1, 2, 3, or 4; z is 0, 1, 2, 3, or 4; or a stereoisomer or a pharmaceutically acceptable salt thereof.