Patent ID: 7582416

Claim:
A method of identifying an agent that binds to a formyl peptide receptor like-2 (FPRL2) polypeptide, said method comprising: (a) contacting said formyl peptide receptor like-2 (FPRL2) polypeptide which comprises an amino acid sequence which corresponds to SEQ ID NO:2, with a heme binding protein (HBP) polypeptide having an amino acid sequence which is 95% or more identical to SEQ ID NO:18, in the presence or absence of a candidate binding agent under conditions permitting binding of said heme binding protein (HBP) polypeptide to said formyl peptide receptor like-2 (FPRL2) polypeptide; and (b) measuring binding of said formyl peptide receptor like-2 (FPRL2) polypeptide to said heme binding protein (HBP) polypeptide, wherein a decrease in binding in the presence of said candidate binding agent, relative to binding in the absence of said candidate binding agent, identifies said candidate binding agent as an agent that binds to said formyl peptide receptor like-2 (FPRL2) polypeptide.