Patent ID: 7138432

Claim:
An α-amino hydroxamic acid derivative of the formula I, wherein R 1 is hydrogen, substituted or unsubstituted aryl, lower alkyl, substituted or unsubstituted carbocyclic aryl-lower alkyl, substituted or unsubstituted C 3 –C 7 -cycloalkyl, substituted or unsubstituted C 3 –C 7 -cycloalkyl-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, lower alkyl-(thio, sulfinyl or sulfonyl)-lower alkyl, amino-lower alkyl or mono- or di-lower alkylamino-lower alkyl; R 2 is hydrogen or lower alkyl; R 3 is substituted or unsubstituted C 3 –C 7 -cycloalkyl, substituted or unsubstituted carbocyclic aryl; or lower alkyl; A is C 1 –C 3 alkylene unsubstituted or substituted by lower alkyl; q is 1–5; R is C 2 –C 7 -alkyl, which is mono-, di- or trisubstituted by halogen, nitro, lower acyloxy, trifluoromethoxy, cyano, or C 3 –C 5 -cycloalkyl; or C 3 –C 7 -alkenyl or C 3 –C 7 -alkynyl, which in each case is unsubstituted or mono-, di- or trisubstituted by halogen, nitro, lower acyloxy, trifluoromethoxy, cyano, or C 3 –C 5 -cycloalkyl; and pharmaceutically acceptable prodrug acyl derivatives; and pharmaceutically acceptable salts thereof.