Patent ID: 8744779

Claim:
An apparatus for use in delivering anesthesia to a subject, comprising: at least one input element configured to receive drug information regarding a plurality of anesthetic agents for administration to the subject from an anesthetist; at least one input element configured to receive a target for sedative and analgesic effect from the anesthetist for maintenance of the anesthesia; at least one input element configured to receive a target for analgesia versus wakeup time effect from the anesthetist; a display; and at least one processing element configured to receive the drug information and programmed to perform the method, the method comprising: determining concentrations of the plurality of anesthetic agents, including interactions between anesthetic agents of the plurality, to achieve an optimal wakeup time for the subject based on a drug effect model accessed by the at least one processing element; determining concentrations of the plurality of anesthetic agents based on the drug effect model accessed by the at least one processing element, including interactions between anesthetic agents, that will maintain or increase a current sedative and analgesic effect, and minimize the time it takes the subject to wake up after a surgical procedure is complete, and minimize pain awareness and risk of respiratory depression of the subject at and after the desired wakeup time; and modeling at least present and future sedative and analgesic effects of determined concentrations of the plurality of anesthetic agents on the subject based on individual characteristics of the subject and the drug effect model; and depicting on a display: the future sedative and analgesic effects of the determined concentrations; and synergies between the plurality of anesthetic agents; concentrations of the plurality of anesthetic agents for achieving the target sedative and analgesic effect and the target analgesia versus wakeup time effect; concentrations of the plurality of anesthetic agents that will maintain or increase a current sedative effect and lower a risk of respiratory depression of the subject for at least thirty minutes following wakeup; and indicators corresponding to a probability that the plurality of anesthetic agents will be within the desired range of effectiveness on the subject or on a specific part of the general population, the indicators being adjustable automatically or by user input when effectiveness of the plurality of anesthetic agents is different than anticipated or modeled, and the indicators including a lower range indicator below which the plurality of anesthetic agents are less likely to be within a desired range of effectiveness and an upper range indicator above which the plurality of anesthetic agents are more likely to be within the desired range of effectiveness.