Patent ID: 6893611

Claim:
An automatic device for producing a plurality of reaction samples in liquid medium, wherein said device comprises: a first supply plate, comprising N receptacles each intended to contain a first constituent, wherein said plate is a removable microplate; a second supply plate, comprising M receptacles each intended to contain a second constituent, wherein said plate is a removable microplate; a removable plate for samples, comprising a plurality of cavities arranged in the form of an array comprising at least N rows and at least M columns, wherein each cavity is configured to hold a volume on the order of at least ten nanoliters, wherein said cavities are intended to contain a mixture of constituents originating from said first and second supply plates; a piezoelectric micropipette, wherein said micropipette is able to sample a predetermined amount of said first and/or second constituents and to deliver a volume on the order of a nanoliter, wherein said piezoelectric micropipette is capable of delivering at least one drop of said first and/or second constituents into each cavity of said removable plate for samples; a means for displacing said piezoelectric micropipette along at least two perpendicular axes Y, Z so that said piezoelectric micropipette can sample a predetermined amount of said first and/or second constituents from each filled receptacle of said first and second supply plates; and a means for relatively displacing the piezoelectric micropipette and the removable plate for samples.