Patent ID: 6926763

Claim:
A compound having the formula or a pharm,aceutically acceptable salt thereof, wherein A is CR 2 and B is N, in which R 2 is H, C 1-6 alkyl, vinyl, allyl, ethynyl, halo, NH 2 , OH, SH, OR 29 , SR 30 , NR 31 R 32 , wherein R 29 -R 32 are, independently, H or C 1-6 alkyl; wherein n is 0-3; wherein R 3 is H, lower (C 1-3 ) alkyl, lower (C 1-3 ) polyfluoroalkyl, trifluoromethoxy or halo, R 4 is H, methyl, ethyl, lower (C 1-3 ) polyfluoroalkyl, trifluoromethoxy or halo, or R 3 and R 4 are together —(CH 2 ) 3 —; wherein R 1 is (CH 2 ) m —{(G) o —(CH 2 ) p } q —L, in which G is CH 2 , CH═CH, C≡C, CO, O, S, NR 5 , where R 5 is H or C 1-6 alkyl, CHR 6 , where R 6 is OH or C 1-6 alkyl, CH(CR 7 R 8 ), where each of R 7 and R 8 is, independently, H, halo, or C 1-6 alkyl, OCO, CONR 9 , NR 10 CO, where each of R 9 and R 10 is, independently, H or C 1-6 alkyl, SO 2 NH, or NHSO 2 ; in which L is H, halo, substituted or unsubstituted C 1-0 alkyl, substituted or unsubstituted C 3-8 cycloalkyl, substituted or unsubstituted C 6-14 aryl, substituted or unsubstituted C 5-10 heteroaryl, a substituted or unsubstituted 5-8 membered non-aromatic heterocycle, NH 2 , CN, OR 11 , SR 12 , COR 13 , OCOR 14 , NR 15 (CO)R 16 , NR 17 R 18 , NR 19 (CO)NHR 20 , CH(CO 2 R 21 ) 2 , CO 2 R 22 , NHSO 2 R 23 , CONR 24 R 25 , CH 2 COR 26 , S(O)R 27 or S(O 2 )R 28 in which each of R 11 -R 28 is, independently, H, substituted or unsubstituted C 1-6 alkyl, substituted or unsubstituted C 3-8 cycloalkyl, substituted or unsubstituted C 6-14 aryl, substituted or unsubstituted C 7-20 arylalkyl, substituted or unsubstituted C 7-20 alkylaryl, or substituted or unsubstituted C 5-12 heteroaryl; in which m is 1-4, o is 0-4, p is 0-4, and q is 0-4.