Patent ID: 8337815

Claim:
A biomimetic pulmonary surfactant comprising: dipalmitoyl phosphatidylcholine, phosphatidyl glycerol, a synthetic surfactant polypeptide having at least 10 amino acid residues and no more than 60 amino acid residues, the synthetic surfactant polypeptide including a sequence having alternating hydrophobic and hydrophilic amino acid residue regions represented by the formula (Z a U b ) c Z d , wherein: Z is a hydrophilic amino acid residue independently selected from the group consisting of R and K; U is a hydrophobic amino acid residue independently selected from the group consisting of L and C; a is 1 or 2; b has an average value of about 3 to about 8; c is 1 to 10; and d is 0 to 2, and essentially neutral lipid, and having essentially no 1-palmitoyl 2-oleoyl phosphatidylglycerol and essentially no palmitic acid.