Patent ID: 8841464

Claim:
A substituted pyran compound having the structural formula I: or a pharmaceutically acceptable salt, ester, carbamate, imide, or amide thereof, wherein A and A′ are individually selected from the group consisting of optionally substituted C 4 -C 14 aryl and heteroaryl wherein heteroatoms of heteroaryl A and/or A′ are selected from the group consisting of O, N, and S; Z is a chemical bond or —Y—(CH 2 ) o —; Y is NH or O; o is 0, 1, 2, 3, or 4; R is H, C 1-8 alkyl, C 2-8 alkenyl, or C 2-8 alkynyl; W is —OH or —NHR; B is optionally substituted C 4 -C 14 aryl or optionally substituted C 4 -C 14 heteroaryl; and n and m are each independently 0, 1, 2, 3, or 4.