Patent ID: 7863019

Claim:
A method for producing a monoclonal antibody immunoreactive with IL-15 receptor, said method comprising the steps of: a) immunizing an animal with a composition comprising (i) an IL-5 receptor polypeptide selected from the group consisting of a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:2, a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:7, a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:9, a polypeptide comprising the amino acid sequence set forth in SEQ ID:11, and a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:13, or (ii) an immunogenic fragment of a polypeptide defined by (i); b) harvesting spleen cells from the immunized animal; c) fusing said spleen cells to a myeloma cell line, thereby generating hybridoma cells; d) identifying a hybridoma cell line that produces monoclonal antibodies immunoreactive with IL-15 receptor; and e) purifying monoclonal antibodies produced by said hybridoma cell line, thereby producing said monoclonal antibody.