Patent ID: 7348325

Claim:
A compound having Formula I or a salt thereof or Formula II or a salt thereof: wherein: R is O: Y is CH: each R 2 is independently, H, halogen, cyano, NO 2 , C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, C 3 to C 7 cycloalkyl, substituted C 3 to C 7 cycloalkyl, a C 6 to C 14 aryl, a substituted C 6 to C 14 aryl, a 5 to 14 membered heteroaryl, a substituted 5 to 14 membered heteroaryl, an arylalkyl, a substituted arylalkyl, a 5 to 14 membered heterocycloalkyl, or a substituted 5 to 14 membered heterocycloalkyl; B is O, S, SO,or SO 2 ; W and X are each independently C or N; n and 1 are independently 1 to 4; p is 0 to 4; R 3 is H or C 1 to C 6 alkyl; R 5 and R 6 are independently, H, halogen, haloalkyl, NO 2 , cyano, OR 26 , NR 27 R 28 , CO 2 R 29 , C(O)NR 30 R 31 , SO 2 R 32 , SO 2 NR 33 R 34 , NR 35 SO 2 R 36 , NR 37 C(O)R 38 , NR 39 CO 2 R 40 , —CO(CH 2 ) p R 41 , —CONH(CH 2 ) p R 42 , —-OCONH(CH 2 ) p R 42 , O-alkylaminoalkyl, alkylaminoalkynyl, C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, C 3 to C 7 cycloalkyl, substituted C 3 to C 7 cycloalkyl, alkenyl, substituted alkenyl, alkenylalkyl, substituted alkenylalkyl, alkynyl, substituted alkynyl, hydroxyalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, arylalkyl, substituted arylalkyl, heterocycloalkyl, or substituted heterocycloalkyl; R 8 and R 14 are independently C 6 to C 14 aryl, substituted C 6 to C 14 aryl, 5 to 14 membered heteroaryl, or substituted 5 to 14 membered heteroaryl; each R 10 is independently H, C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, C 3 to C 7 cycloalkyl, substituted C 3 to C 7 cycloalkyl, C 6 to C 14 aryl, substituted C 6 to C 14 aryl, 5 to 14 membered heteroaryl, substituted 5 to 6 membered heteroaryl, 5 to 6 membered heterocycloalkyl, or substituted 5 to 6 membered heterocycloalkyl; R 12 is H, alkoxy, C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, C 3 to C 7 cycloalkyl, substituted C 3 to C 7 cycloalkyl, C 6 to C 14 aryl, substituted C 6 to C 14 aryl, 5 to 14 membered heteroaryl, substituted 5 to 14 membered heteroaryl, —CO 2 R 48 , —C(O)NR 49 R 50 , SO 2 R 51 , or SO 2 NR 52 R 53 ; and R 26 , R 27 , R 28 , R 29 , R 30 , R 31 , R 32 , R 33 , R 34 , R 35 , R 36 , R 37 , R 38 , R 39 , R 40 , R 41 , R 42 , R 48 , R 49 , R 50 , R 51 , R 52 , and R 53 are independently H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroaryl, substituted heteroaryl, heterocycloalkyl, or substituted heterocycloalkyl.