Patent ID: 8563575

Claim:
A method for treating schizophrenia, autism, Alzheimer's disease, bipolar disorders, Parkinson's disease or Huntington's disease in a mammal, which comprises administering an effective amount of a compound represented by the formula (I) to the mammal: wherein ring A represents an optionally substituted 6-membered ring, any one of Z 1 to Z 4 represent —N═, and the others represent —CH═; Y represents an oxygen atom, a sulfur atom, an optionally substituted methylene group or —NR c —; R c represents a hydrogen atom, or a substituent; and R represents (1) a group represented by the formula: wherein R 1 represents a 5- to 10-membered heterocyclic group, which is optionally substituted; L represents a sulfur atom, an oxygen atom, an optionally substituted methylene group, —CO—, —NR a —, —CH 2 O—, —OCH 2 —, —NR a COO—, —OCONR a —, —NR a CONR b —, —NR a COCH 2 —, —CH 2 CONR a —, —NR a CO—, —CONR a —, R a and R b are the same or different and each represents a hydrogen atom, or an optionally substituted C 1-6 alkyl group, or L and R 1 in combination optionally form an optionally substituted bi- or tri-cyclic fused heterocyclic group; and ring B 1 represents a benzene ring, a pyridine ring, a pyrimidine ring, a pyrazine ring or a pyridazine ring, each of which is optionally substituted; or (2) a group represented by the formula: wherein R 2 represents a phenyl group or 5- to 10-membered heterocyclic group, each of which is optionally substituted; the partial structure of the formula: is wherein R x1 and R x2 are the same or different and each is a hydrogen atom or an optionally substituted C 1-6 alkyl group, R x3 , R x4 and R x5 are each a hydrogen atom or an optionally substituted C 1-6 alkyl group, and the ring-constituting atom(s) optionally further have substituent(s), or a salt thereof.