Patent ID: 8669272

Claim:
A compound of the formula IIa: wherein: B is selected from the group consisting of phenyl, napthyl, tetrahydroquinolinyl, tetrahydroisoquinolinyl, quinolinyl, and isoquinolinyl; R 1a , R 1b and R 1c are independently selected from the group consisting of: (1) hydrogen, (2) halogen, (3) hydroxyl, (4) C 1-6 alkyl, which is unsubstituted or substituted with halogen, hydroxyl, phenyl or napthyl, (5) —O—C 1-6 alkyl, which is unsubstituted or substituted with halogen, hydroxyl or phenyl, (6) heteroaryl, wherein heteroaryl is selected from triazolyl, oxazolyl, pyrrolyl, imidazolyl, indolyl, pyridyl, and pyrimidinyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 , (7) phenyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 , (8) —O-phenyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 , and (9) —NH—C 1-6 alkyl, or —N(C 1-6 alkyl)(C 1-6 alkyl), which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 ; R 2a , R 2b and R 2c may be absent if the valency of B does not permit such substitution and are independently selected from the group consisting of: (1) hydrogen, (2) halogen, (3) hydroxyl, (4) C 1-6 alkyl, which is unsubstituted or substituted with halogen, hydroxyl or phenyl or napthyl, (5) —O—C 1-6 alkyl, which is unsubstituted or substituted with halogen, hydroxyl or phenyl, (6) heteroaryl, wherein heteroaryl is selected from pyrrolyl, imidazolyl, indolyl, pyridyl, and pyrimidinyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 , (7) phenyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 , (8) —O-phenyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 , and (9) —NH—C 1-6 alkyl, or —N(C 1-6 alkyl)(C 1-6 alkyl), which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, —O—C 1-6 alkyl or —NO 2 ; R 3 is C 1-6 alkyl; or a pharmaceutically acceptable salt thereof.