Patent ID: 7115654

Claim:
A compound of the formula wherein: R 1 is chosen from optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; L is a linker selected from the group consisting of —(CH 2 ) m —O—(CH 2 ) n —; —(CH 2 ) m —NR—(CH 2 ) m —; —(CH 2 ) m —NRCONR—(CH 2 ) n —; (CH 2 ) m —NRCOO—(CH 2 ) n —; —(CH 2 ) m —CONR—(CH 2 ) n —; —(CH 2 ) m —NRCO—(CH 2 ) n —; —(CH 2 ) m —NRSO 2 —(CH 2 ) n —; —(CH 2 ) m —CO—(CH 2 ) n —; —(CH 2 ) m —NRCONRSO 2 —(CH 2 ) n —; —(CH 2 ) m —NRCONRCO—(CH 2 ) n —; —(CH 2 ) m —SO 2 —(CH 2 ) n —; —(CH 2 ) m —SO 2 CH 2 CO—(CH 2 ) n —; —(CH 2 ) m —SO 2 NR—(CH 2 ) n —; —(CH 2 ) m —SCH 2 CO—(CH 2 ) n — and —Z—(CH 2 ) m —Ar—(CH 2 ) n — where Z is —C(═O)NH—, —NHC(═O)—, or —SO 2 NH—, Ar is a 5 membered heroarylene, m and n are each 0, 1, 2, 3, 4, or 5, and wherein R is each independently hydrogen, C 1 –C 5 alkyl, C 1 –C 5 hydroxyalkyl, or C 1 –C 5 alkylhalide; R 2 is chosen from H, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; and Y is or single stereoisomers, mixtures of stereoisomers, or the pharmaceutically acceptable salts, amides, or esters thereof.