Patent ID: 6884793

Claim:
A combination preparation for contraception comprising a first stage consisting of two daily dosage portions, each consisting of an effective amount of estradiol valerate; a second stage consisting of a first group and a second group of daily dosage portions of a combination of said estradiol valerate and dienogest; a third stage consisting of two daily dosage portions, each consisting of an effective amount of said estradiol valerate, wherein said effective amount of said estradiol valerate in each of said two daily dosage portions in said third stage is the same, but smaller than said effective amount of said estradiol valerate in each of said two daily dosage portions in said first stage; and an additional stage consisting of two daily dosage portions, each consisting of a pharmaceutically acceptable placebo; wherein said first group of said daily dosage portions of said second stage consists of five of said daily dosage portions of said combination and wherein said second group of said daily dosage portions of said second stage consists of seventeen of said daily dosage portions of said combination; and wherein respective amounts of said estradiol valerate in each of said daily dosage portions of said second stage are equal and respective amounts of said dienogest in said daily dosage portions of said second group of said second stage are equal to 1.5 to 3 times corresponding amounts of said dienogest in said daily dosage portions of said first group of said second stage.