Patent ID: 8575282

Claim:
A modified macromolecule that has at least one further functional group, comprising at least one x-fold (x≧1) chemoselectively incorporated phosphoramidate group of general formula (I) —NHPO(OR 1 )(OR 1′ ) (I) and/or at least one x-fold (x≧1) chemoselectively incorporated phosphonamide group of general formula (1a) —NHPO(R 1 )(OR 1′ ) (Ia) wherein R 1 and R 1′ is selected from the group containing glycerol, polyglycerol, PEG polymers of the general empirical formula C 2n H 4n+2 O n+1 with n≧1, methyl, ethyl, or butyl; functionalized C n -alkyl chains with n≧1, aryls, heteroaryl, silyl, fluorophores, saccharides, peptides, crown ethers, or a linker, which links the aforementioned groups, and wherein R 1 and R 1′ can be identical to or different from one another, wherein the further functional group in the macromolecule is unprotected.