Patent ID: 7455855

Claim:
A method of treating a disease of a retina, an optic nerve or a vitreous body comprising administering to an eye or eyes of a patient a pharmaceutically effective amount of a delivering substance represented by the following formula [1] consisting essentially of a polyalkylene glycol, a phospholipid and a drug linked by covalent bonds solely or combined with a pharmaceutically acceptable carrier or additive, (A m —X—Y— B) n [1] wherein A and B, being the same or different, are residues of the drug; X is polyalkylene glycol or a reactive derivative thereof having aminoalkyl, carboxyalkyl, mercaptoalkyl, hydrazidoalkyl, maleimidoalkyl, sulfonyalkyl, vinylsulfonylalkyl or vinylcarbonyl introduced into one or both terminals of the polyalkylene glycol, Y is a residue of the phospholipid, m is 0 or an integer of 1 or more, n is 0, 1 or 2, at least one of m and n is not 0, and all of A, B, X and Y are linked by the covalent bonds.