Patent ID: 8299255

Claim:
A 3,8-diaminotetrahydroquinoline derivative represented by formula (1a): wherein X represents CH 2 , C═O, CH—OR, CH—SR, or CH—NRR′; m is a number of 1 or 2; Ar represents a phenyl group, a naphthyl group, a 5-membered or 6-membered aromatic heterocyclic group having one or two elements selected from S, N, and O, or a condensed aromatic heterocyclic group formed between a benzene ring and a 5-membered or 6-membered heterocyclic ring having one or two elements selected from S, N, and O, wherein the phenyl, naphthyl, or aromatic heterocyclic groups may be substituted by 1 to 3 halogen atoms, a C1 to C6 alkyl group, or a C1 to C6 alkoxy group; R 1 and R 2 , which may be identical to or different from each other, each represent a hydrogen atom or a methyl group; R 3 represents a C1 to C6 alkyl group, the alkyl group optionally being substituted by a methylthio or benzyloxy group, a phenyl group, a phenyl-C 1-4 alkyl group, or an indolyl-C 1-4 alkyl group, the phenyl group or the indolyl group optionally being substituted by a C1 to C6 alkyl group, a halogen atom, a hydroxyl group, or a C1 to C6 alkoxy group; n is a number of 0 or 1; R 4 and R 5 , which may be identical to or different from each other, each represent a hydrogen atom, or a C1 to C6 linear, branched, or cyclic alkyl group, the alkyl group optionally being substituted by a halogen atom, a hydroxyl group, a C1 to C6 alkoxy group, a phenyl group, a benzyloxy group, or a hydroxyphenyl group, or R 4 or R 5 , and R 6 or R 7 may be linked to the adjacent nitrogen atom to form a pyrrolidine ring or a piperidine ring, the pyrrolidine ring or the piperidine ring optionally being substituted by a hydroxyl group; R 6 and R 7 , which may be identical to or different from each other, each represent a hydrogen atom or a C1 to C6 alkyl group; and R and R′, which may be identical to or different from each other, each represent a hydrogen atom or a C1 to C6 linear, branched, or cyclic alkyl group, or a salt thereof.