Patent ID: 7297478

Claim:
A library of linker nucleic acid molecules or sequences, each of which joins two nucleic acid domains or two nucleic acid sequences encoding two polypeptide domains, each of which has a pattern of degenerate repeated triplet nucleotides with the following properties: (i) position 1 of each repeated triplet cannot be the same nucleotide as position 2 of the repeated triplet; or (ii) position 2 of each repeated triplet cannot be the same nucleotide as position 3 of the repeated triplet; or (iii) position 1 of each repeated triplet cannot be the same nucleotide as position 3 of the repeated triplet; and (iv) wherein each of said molecules or sequences that joins said domains does not encode Gly 4 Ser (SEQ ID NO:52) or a repeat thereof.