Patent ID: 8791133

Claim:
A compound of formula I or a physiologically acceptable salt of the compound of formula I, where R1 and R2 are identical or different and are independently of one another hydrogen, —(C 1 -C 6 )-alkyl, —O—(C 1 -C 6 )-alkyl, aryl, halogen or hetaryl, where alkyl, aryl and hetaryl are in each case unsubstituted or mono-, di- or trisubstituted independently of one another by F, Cl, Br, CN, —(C 1 -C 4 )-alkyl, —O—(C 1 -C 4 )-alkyl, or —CF 3 ; R3 is OH, —O—(C 1 -C 8 )-alkyl, —O—(C 1 -C 6 )-alkylene-NH—C(O)—O—(C 1 -C 4 )-alkyl, —O—(C 1 -C 6 )-alkylene-NH 2 , —NH 2 , —NH—(C 1 -C 8 )-alkyl, —NH—(C 1 -C 6 )-alkylenearyl, —NH—(C 1 -C 8 )-alkylene-O—(C 1 -C 4 )-alkyl, —NH—(C 1 -C 8 )-alkyl-OH, —NH—(C 1 -C 6 )-alkylene-NH—C(O)—O—(C 1 -C 4 )-alkyl, —NH—(C 1 -C 6 )-alkylene-NH 2 , —NH—(C 0 -C 6 )-alkylene-(C 3 -C 7 )-cycloalkyl, —NH—(C 0 -C 6 )-alkylenehetaryl, —N((C 1 -C 4 )-alkyl) 2 , or a cyclic amine which is selected from the group consisting of morpholine, piperazine, piperidine, pyrrolidine and thiomorpholine, and is attached via the nitrogen atom, where aryl, cycloalkyl, and hetaryl are in each case unsubstituted or mono-, di- or trisubstituted independently of one another by F, Cl, —OH, —(C 1 -C 4 )-alkyl, —(C 1 -C 4 )-alkylene-NH 2 , —(C 1 -C 4 )-alkylene-OH or —O—(C 1 -C 4 )-alkyl; R4 and R5 are identical or different and are independently of one another hydrogen, —(C 1 -C 6 )-alkyl or phenyl, or R4 and R5 together with the carbon atom to which they are attached form (C 3 -C 7 )-cycloalkyl; X is a covalent bond, CH 2 , CH((C 1 -C 6 )-alkyl), C((C 1 -C 4 )-alkyl) 2 , or oxygen; and wherein the hetaryl comprises 4 to 15 carbon atoms which are present in one, two or three ring systems connected together, and which comprise, depending on the ring size, one, two, three or four identical or different heteroatoms from the group consisting of oxygen, nitrogen and sulfur, or wherein hetaryl is an oxetanyl residue.