Patent ID: 7645601

Claim:
A method of producing a polypeptide which has PGE synthase activity, the method comprising: (a) expressing a nucleic acid which encodes a polypeptide in a suitable expression system to produce the polypeptide recombinantly, wherein the polypeptide is a PGE synthase selected from the group consisting of a polypeptide which is a PGE synthase and which comprises the amino acid sequence of SEQ ID NO. 2 and a polypeptide which is a PGE synthase and which consists of a portion comprising amino acids 30-152 or amino acids 1-130 of the amino acid sequence of SEQ ID NO. 2; (b) testing the recombinantly produced polypeptide for PGE synthase activity, said method optionally comprising isolation of said recombinantly produced polypeptide.