Patent ID: 8722732

Claim:
A compound, of the formula wherein: is selected from the group consisting of 3-methoxyphenyl, 3-chlorophenyl and 1-naphthyl; each R 4 is independently selected from the group consisting of —H, —F, —Cl, —Br, —I, phenyl, —CF 3 , —CF 2 H, —CFH 2 , lower alkyl, —O-lower alkyl, —OCH 2 CF 3 , —OH, —CN, —NO 2 , —C(O)-lower alkyl, —C(O)O-lower alkyl, —C(O)NH-lower alkyl, —C(O)N-lower alkyl 2 , —OC(O)-lower alkyl, and —NH—C(O)-lower alkyl; (a) is an integer from 1 to 5; R 5 is lower alkyl; n is an integer from 10 to about 2000; X is a spacer moiety of the formula —(CR x R y ) a —K w —(CR x R y ) b —(CH 2 CH 2 O) c —(CR x R y ) d —K z —, wherein each R x and R y , in each occurrence, is independently selected from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, and substituted aryl; a is an integer from 0 to 5; b is an integer from 0 to 5; each of K w , and K z , is independently selected from —NH—, —C(O)—, —C(O)NH—, —NH—C(O)—, —O—, —S—, O—C(O)—, C(O)—O—, —O—C(O)—O—, O—C(O)—NH—, —NH—C(O)— —O—; c is an integer from 0 to 10, and d is an integer from 0 to 5; and AA is a single amino acid residue chosen from alanine, valine, leucine, isoleucine, glycine, threonine, serine, cysteine, methionine, tyrosine, phenylalanine, tryptophan, aspartic acid, glutamic acid, lysine, arginine, histidine, and proline, or a pharmaceutically acceptable salt or solvate thereof.