Patent ID: 8609659

Claim:
A compound of formula (I): A 1 -D 1 -T 1 (I) wherein: A 1 is a group of formula (II): wherein: R 1 is phenyl wherein one of the ring hydrogen atoms is substituted with a group selected from C(O)R′, C(O)OR′, C(O)NHR′ or C(O)NR 3 R 4 , wherein: R′ is selected from H, alkyl, alkenyl, alkylthio, and from the following optionally substituted groups: cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl or heteroarylalkyl, R 3 and R 4 , equal to or different from each other, are selected from alkyl, alkenyl, alkylthio, and from the following optionally substituted groups: cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl, heteroarylalkyl, or together with the nitrogen atom to which they are linked, they form a 5-7 membered ring, R 2 is phenyl, wherein one or more hydrogen atoms of the ring are optionally substituted with groups selected from: halogen, alkyl, cycloalkyl, heterocycloalkyl, phenyl, benzyl, heteroaryl, alkenyl, alkylthio, cyano, SO 2 NH 2 , isothiocyanate, OR 5 , NO 2 , NHR 5 or NR 6 R 7 , wherein: R 5 is selected from H, alkyl, alkenyl, alkylthio, and from the following optionally substituted groups: cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl or heteroarylalkyl, R 6 and R 7 , equal to or different from each other, are selected from alkyl, alkenyl, alkylthio, and from the following optionally substituted groups: cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl, heteroarylalkyl, or together with the nitrogen atom to which they are linked, they form a 5-7 membered ring. D 1 is a structure of formula (D1): wherein t is 1 and, Q 1 is —-CH 2 —CH 2 , T 1 is a group selected from H, alkyl, alkenyl, alkynyl, and from the following optionally substituted groups: cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl or heteroarylalkyl, wherein when R′, R 3 , R 4 , T 1 have the meaning of cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl, heteroarylalkyl groups, when R 2 is substituted with cycloalkyl, heteroacycloalkyl, phenyl, benzyl or heteroaryl, one or more hydrogen atoms of the ring are optionally substituted with one or more groups selected from halogen, alkyl, cycloalkyl, heterocycloalkyl, phenyl, benzyl, heteroaryl, alkenyl, alkylthio, cyano, SO 2 NH 2 , isothiocyanate, OR 5 , NO 2 , NHR 5 or NR 6 R 7 , wherein R 5 , R 6 and R 7 are as above defined, and pharmaceutically acceptable salts or stereoisomers thereof.