Patent ID: 7470794

Claim:
A compound of formula I: where the hydroxamic acid moiety and the sulfonamido moiety are bonded to adjacent carbons of group A wherein: A is phenyl optionally substituted by one or more of R 1 , R 2 , R 3 and R 4 ; Z is phenyl optionally substituted by one or more of R 10 , R 11 , R 12 and R 13 ; E is NR 5 , O, or S; G is CH 2 or a bond; Y is alkyl optionally substituted with R 20 , R 21 , R 22 , or R 23 ; J is benzodioxolyl optionally substituted with R 14 , R 15 , R 16 , or R 17 ; L is —C(O)—, —NR 5 C(O)NR 6 —, —NR 5 C(O)O—, —OC(O)NR 5 —, —NR 5 C(O)—, or —C(O)NR 5 ; R 1 , R 2 , R 3 , R 4 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , and R 17 are independently —F, —Br, —Cl, —I, —OR 5 , —C 1 -C 4 -perfluoroalkyl, —NR 5 R 6 , or straight chain or branched —C 1 -C 6 alkyl, —C 2 -C 6 -alkenyl, or —C 2 -C 6 -alkynyl, each optionally substituted with —OR 5 , or —NR 5 R 6 ; R 20 , R 21 , R 22 , or R 23 are independently —F, —Br, —Cl, —I, or —OR 5 ; R 5 and R 6 are independently H, alkyl, or C 1 -C 4 -perfluoroalkyl; and R 7 is hydrogen, alkyl, or aryl; or a pharmaceutically acceptable salt thereof.