Patent ID: 8900626

Claim:
A transdermal drug delivery system for treatment of an eyelid disease comprising a pressure sensitive adhesive layer provided on a support, wherein the pressure sensitive adhesive layer comprises a steroid and a pressure sensitive adhesive, wherein the steroid is selected from the group consisting of clobetasol propionate, clobetasol butyrate, betamethasone dipropionate, amcinonide, and loteprednol etabonate, wherein the pressure-sensitive adhesive is selected from the group consisting of acrylic pressure sensitive adhesives, rubber-based pressure sensitive adhesives and silicone-based pressure sensitive adhesives, wherein, if the pressure-sensitive adhesive is an acrylic pressure sensitive adhesive, the acrylic pressure sensitive adhesive is either an alkyl (meth)acrylate-vinyl acetate copolymer or an acrylate-vinylacetate copolymer, wherein, if the pressure-sensitive adhesive is a rubber-based pressure sensitive adhesive, the rubber-based pressure sensitive adhesive is a styrene-isoprene-styrene block copolymer, wherein the transdermal drug delivery system has a shape capable of being applied along a skin surface of the upper eyelid, a skin surface of the lower eyelid, or a skin surface of both eyelids, and wherein the transdermal drug delivery system is capable of administering a therapeutically effective amount of the steroid to the eyelid with negligible irritation.