Patent ID: 7897624

Claim:
A compound of formula I, or a pharmaceutically acceptable salt or tautomer thereof: wherein B is H, C 1 -C 6 alkyl or C 2 -C 6 alkenyl; wherein said C 1 -C 6 alkyl is optionally substituted with one or two groups independently selected from the group consisting of hydroxy, alkoxy, and oxy; A and A′ are each independently H, C 1 -C 6 alkyl, or C 2 -C 6 alkenyl; wherein each C 1 -C 6 alkyl is optionally substituted with one or two groups independently selected from the group consisting of hydroxy, alkoxy, and oxy; or A and A′ together with the carbon atom to which they are attached, form a cyclopropyl, cyclobutyl, or cyclopentyl group, wherein each cyclopropyl, cyclobutyl, or cyclopentyl group is optionally substituted with one or two groups independently selected from the group consisting of methyl, hydroxy, and halogen; X and Y are each independently halogen, methyl, SCH 3 or trifluoromethyl; R 1 is H, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 5 -C 6 cycloalkenyl or C 2 -C 6 alkynyl; wherein each alkyl, cycloalkyl, alkenyl, cycloalkenyl or alkynyl group is optionally substituted with 1-3 substituents independently selected from the group consisting of halogen, hydroxy, C 1 -C 4 alky, C 1 -C 4 alkoxy, cyano, cyanomethyl, nitro, azido, trifluoromethyl difluoromethoxy and phenyl; and R 2 is H, halogen, hydroxy, azido, cyano, cyanomethy, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 5 -C 6 cycloalkenyl or C 2 -C 6 alkynyl, wherein each alkyl, cycloalkyl, alkenyl cycloalkenyl or alkynyl group is optionally substituted with 1-3 substituents independently selected from the group consisting of halogen, hydroxy, C 1 -C 4 alkoxy, cyano, cyanomethyl, nitro, azido, trifluoromethyl and phenyl.