Patent ID: 7482344

Claim:
A compound of the formula: wherein, Z represents CH 2 , S, or O; Ar represents a group of the formula: R 1 represents hydrogen or (C 1 -C 6 )alkyl; R 2 represents amino or NH SO 2 R 4 ; R 3 represents hydrogen, (C 1 -C 6 )alkyl, heterocycle, substituted heterocycle, (C 1 -C 4 )alkyl-heterocycle, or (C 1 -C 4 )alkyl-substituted heterocycle, provided that where Ar represents: then Z is other than O; R 4 represents independently at each occurrence (C 1 -C 6 )alkyl; R 5 and R 6 represent independently at each occurrence hydrogen, fluoro, chloro, hydroxy, difluoromethyl, trifluoromethyl, (C 1 -C 6 )alkoxy, (C 1 -C 4 )alkyl-(C 3 -C 7 )cycloalkyl, (C 1 -C 4 )alkoxy-(C 3 -C 7 )cycloalkyl, NHR 7 , or N(R 7 ) 2 wherein R7 represents independently at each occurrence (C 1 -C 6 )alkoxy or (C 3 -C 7 )cycloalkyl; or a pharmaceutically acceptable salt thereof.