Patent ID: 7820670

Claim:
An ophthalmic pharmaceutical composition useful in the treatment of glaucoma and control of intraocular pressure, comprising an effective amount of a compound according to Formula I, or a pharmaceutically acceptable salt thereof: where: Y=NHR 7 , R 7 =H, C 1 -C 4 alkyl optionally substituted by —(CH 2 ) n NR 5 R 6 , —(CH 2 ) n OH, or —(CH 2 ) n OR 4 ; or Y=NR 7 R 8 where R 7 and R 8 together form a heterocyclic ring optionally substituted by —(CH 2 ) n NR 5 R 6 , or —(CH 2 ) n OH; R 4 =C 1 -C 6 alkyl, aryl, heteroaryl; R 5 , R 6 independently=H, C 1 -C 6 alkyl optionally substituted OH, OR 4 , aryl, or heteroaryl; R= and OR n=0-4; and a pharmaceutically acceptable vehicle therefor.