Patent ID: 8467842

Claim:
A system, comprising: an energy-emitting component including at least a first energy emitter and a second energy emitter, the energy-emitting component configured to interrogate at least one focal volume with a spatially-patterned pulsed multiplexed electromagnetic energy stimulus having a spatial distribution including at least a first region and a second region different from the first region, the second region having a peak emission wavelength different from the first region; circuitry configured to detect nonlinear multi-harmonic response energy associated with hemozoin nanoparticles within the at least one focal volume interrogated by the spatially-patterned pulsed multiplexed electromagnetic energy stimulus; and circuitry configured to compare information associated with the detected nonlinear multi-harmonic response energy to a reference hemozoin response profile, and determine one or more of a presence, an absence, and a severity of malaria condition based on the comparison.