Patent ID: 8574498

Claim:
A biochip with a three-dimensional mesoporous layer, comprising: a substrate covered with a three-dimensional mesoporous aerogel layer, wherein said three-dimensional mesoporous aerogel layer is formed by coating a precursor solution that comprises an ionic liquid and at least one alkoxide monomer and/or aryloxide monomer and then performing a gelation process where the precursor solution comprises the ionic liquid about 20˜50 wt % of the at least one alkoxide monomer and/or aryloxide monomer; the surface of said three-dimensional mesoporous aerogel layer is modified by a modifier that is an alkoxide monomer and/or aryloxide monomer with at least one specific moiety; said specific moiety comprises one selected from the group consisting of the following: amine group, hydroxyl group, carboxyl group, and epoxy group; a converter having a first moiety and a second moiety is linked with the specific moiety so as to have the surface of said three-dimensional mesoporous layer having the second moiety; wherein the substrate is silicon chip, glass, or polymer; and the porosity of said three-dimensional mesoporous layer ranges about 50% to 90%.