Patent ID: 8741924

Claim:
A compound having the structure: wherein: m=1-6; R 1 is quinoline or isoquinoline, partially or fully hydrated, and optionally substituted with R′, OR′, SR′, (CH 2 ) n′ NHR′ or (CH 2 ) n′ N(R′) 2 , wherein n′=0-6, and R′ is independently H, or branched or unbranched C 1-6 alkyl or heteroalkyl; R 2 is (i) keto or thioketo; or (ii) R″, OR″, SR″, NHR″ or N(R″) 2 , wherein R″ is independently H, or branched or unbranched C 1-6 alkyl or heteroalkyl; R 3 and R 4 are, independently, H or (CH 2 ) n R where R is aryl and n=1-6; R 5 is (CH 2 ) n′″ N(R 3 ) 2 or (CH 2 ) n′″ COX wherein X is R′″, OR′″, SR′″, NHR′″ or N(R′″) 2 , wherein n′″=0-6, and R′″ is independently H, or branched or unbranched C 1-6 alkyl or heteroalkyl; and R 6 is quinoline or isoquinoline, partially or fully hydrated, and optionally substituted with R IV , OR IV , SR IV , (CH 2 ) N IV NHR IV or (CH 2 ) n IV N(R IV ) 2 , wherein n IV =0-6, and R IV is independently H, or branched or unbranched C 1-6 alkyl or heteroalkyl; or a pharmaceutically acceptable salt thereof.