Patent ID: 6843993

Claim:
An anti-microbial-adhesion pharmaceutical composition for administration to a patient in need of such a composition comprising a suitable food carrier and an effective amount of an isolated adhesion inhibitory fraction from Vaccinium juice as an active ingredient and a pharmaceutically acceptable carrier or diluent, said isolated fraction having (a) a molecular weight of ≧14,000 kDa dialyzed using dialysis tubing with a 12,000-14,000 molecular weight cut-off; and (b) anti-adhesion activity against H. pylori, (c) an elemental analysis of carbon 43-51%, hydrogen 4-5%, no nitrogen, no sulfur and no chlorine; (d) an nuclear magnetic resonance (NMR) line spectrum as set forth in FIGS. 2A and 2B ; (e) an ultraviolet spectrum with an absorption peak at 280 nm in neutral or acidic pH solution which is absent in alkali solutions; (f) coaggregation reversal and coaggregation inhibition activity against oral bacteria and (g) an adhesion inhibitory activity against P fimbriated bacteria; and wherein the concentration of the isolated adhesion inhibitory fraction is between 1 μg and 10 mg per milliliter (ml).