Patent ID: 8058449

Claim:
A compound of Formula (I) wherein R is a C 6 -C 12 substituted or unsubstituted aryl, a C 5 -C 12 substituted or unsubstituted heteroaryl, a C 1 -C 6 substituted or unsubstituted alkyl or â€”NRâ€²Râ€², Q is C(O), O, NRâ€², S(O) 2 , C(O) 2 , or (CH2)p Y is C(O), O, NRâ€², S(O) 2 , C(O) 2 , or (CH2)p Z is H or C 1 -C 4 alkyl, m is 0, 1, 2, 3, 4 or 5 n is 0, 1, 2, 3, 4, 5 or 6 p is 0, 1, 2, 3, 4, 5 or 6 Râ€² is H, C(O), S(O) 2 , C(O) 2 , a C 6 -C 12 substituted or unsubstituted aryl, a C 5 -C 12 substituted or unsubstituted heteroaryl or a C 1 -C 6 substituted or unsubstituted alkyl, when substituted, aryl, heteroaryl and alkyl are substituted with halogen, C 5 -C 12 heteroaryl, â€”NRâ€²Râ€² or COOZ, wherein at least one of Q and Y comprises a heteroatom selected from the group consisting of O, S, and N, further wherein (i) at least one of R or Râ€² is a C 6 -C 12 aryl or C 5 -C 12 heteroaryl substituted with a halogen or (ii) at least one of R or Râ€² is a C 5 -C 12 heteroaryl, or a pharmaceutically acceptable salt of the compound of Formula (I).