Patent ID: 8686131

Claim:
A trisaccharide building block of General Formula XXIII, wherein: X 2 is selected from the group consisting of a hydroxyl group; thioalkyl, thioaryl, halogen, trichloroacetimidoyl, and a t butyldiphenylsilyloxy; and wherein the stereochemistry may be alpha or beta; R P1 is selected from the group consisting of 4-methoxyphenyl, benzyl, substituted benzyl groups, alkylacyl, arylacyl and alkylarylacyl, or substituted alkylacyl, arylacyl and alkylarylacyl protecting groups, and carbonate protecting groups; R P2 is selected from the group consisting of alkylacyl, arylacyl and alkylarylacyl, or substituted alkylacyl, arylacyl and alkylarylacyl protecting groups, carbonate protecting groups, silyl protecting groups, carbamate protecting groups, and C 3 -C 5 alkenyl; R E1 is selected from the group consisting of methyl, C 2 -C 5 alkyl, substituted alkyl, C 3 -C 5 alkenyl, benzyl and substituted benzyl groups; R B1 is selected from the group consisting of an azido function, an amine, an NH-Dde and NH-DTPM group, or R H2 and R B1 can combine together to form a cyclic carbamate; R H is selected from the group consisting of benzyl or substituted benzyl protecting group, allyl, and allyloxycarbonyl; R H2 is selected from the group consisting of benzyl or substituted benzyl protecting group, allyl, and allyloxycarbonyl, or R H2 and R B1 independently can combine together to form a cyclic carbamate; R S5 is selected from the group consisting of 4-methoxyphenyl, substituted benzyl groups, alkylacyl, arylacyl or alkylarylacyl, and substituted alkylacyl, arylacyl or alkylarylacyl protecting groups; carbonate protecting groups, a t butyldiphenylsilyl, allyl, methoxymethyl, methoxyethyl, and benzyloxymethyl; or R S5 and R H can be combined to form a cyclic acetal or ketal moiety; R S3 is selected from the group consisting of 4-methoxyphenyl, substituted benzyl groups, alkylacyl, arylacyl or alkylarylacyl, and substituted alkylacyl, arylacyl or alkylarylacyl protecting groups, carbonate protecting groups, a t butyldiphenylsilyl or other such substituted silyl protecting group, allyl, methoxymethyl, methoxyethyl, and benzyloxymethyl; R S4 is selected from the group consisting of 4-methoxyphenyl, substituted benzyl groups, alkylacyl, arylacyl or alkylarylacyl, and substituted alkylacyl, arylacyl or alkylarylacyl protecting groups, carbonate protecting groups, a t butyldiphenylsilyl, allyl, methoxymethyl, methoxyethyl, and benzyloxymethyl; or R S4 and R B may be combined to form a cyclic carbamate; and, R B is selected from the group consisting of an azido function, an amine, an NH-Dde and an NH-DTPM group, or R S4 and R B can combine together to form a cyclic carbamate.