Patent ID: 8709232

Claim:
A method of determining blood glucose concentration with a glucose measurement system that includes a test strip and test meter, the test meter having a microcontroller programmed to apply a plurality of test voltages to the test strip and measure a current transient output resulting from an electrochemical reaction in a test chamber of the test strip, the method comprising: inserting the test strip into a strip port connector of the test meter to connect at least two electrodes of the test strip to a strip measurement circuit; initiating a test sequence after deposition of a sample; applying a first voltage and measuring a first current for a first time duration; switching the first voltage to a second voltage different than the first voltage; changing the second voltage to a third voltage different from the second voltage; measuring a second current output of a current transient from the electrodes after the changing from the second voltage to the third voltage; estimating a third current that approximates a steady state current output of a current transient after the third voltage is maintained at the electrodes; calculating a blood glucose concentration based on the first, second and third current outputs of the current transients with an equation of the form: G 1 = (  i ⁢ ⁢ 2 ⁢ ⁢ corr ′   i L ′  ) ′ ⁢ p ⁢ ( a ′ ⁢  i ⁢ ⁢ 2 ⁢ ⁢ corr ′  - zgr ′ ) + d ; where: G 1 is proportional to glucose concentration; i R = ∑ t = 4.4 t = 5 ⁢ ⁢ i ⁡ ( t ) ; ⁢ ⁢ i L ′ = ( ∑ t ~ 1.4 ⁢ ⁢ sec ⁢ ⁢ s t ~ 4 ⁢ ⁢ sec ⁢ ⁢ s ⁢ ⁢ i ⁡ ( t ) ) - 41 ⁢ ( i 2 ) ; ⁢ ⁢ i ⁢ ⁢ 2 ⁢ ⁢ corr ′ = (  i 4.1  + b ′ ⁢  i 5  - c ⁢  i 1.1   i 4.1  + b ′ ⁢  i 5  ) ⁢ i R where: a′ is approximately 0.14, b′ is approximately 4.9, c is approximately 4.24, d is approximately 11.28, p′ is approximately 0.548, and zgr′ is approximately 9.38; i 4.1 comprises the current measured during application of the third voltage; i 5 comprises the current measured during application of the third voltage; i 1.1 comprises the current measured during application of the second voltage; and i 2 comprises the current measured during application of the second voltage.