Patent ID: 8690419

Claim:
A cartridge for storage and sterile delivery of a two-phase compound, composed of a liquid phase and a solid phase which are mixed together in said cartridge immediately before delivery of said compound, comprising: a first tubular member which defines a first chamber for storage of said solid phase, with a first side wall having an open end and a bottom wall, said first tubular member defining a longitudinal axis; a second tubular member with a second side wall, a first and a second end walls, defining a second hermetically sealed chamber for storage of said liquid phase, said second hermetically sealed chamber forming with said first chamber a hermetically sealed space in said cartridge for the storing and mixing of said liquid and solid phases, said second tubular member defining a piston which sealably slides within said first tubular member for extrusion of said compound, the bottom wall of said first tubular member having an opening for the passage of the compound to be delivered from said cartridge; and occlusion means for occluding said opening; wherein said occlusion means comprise a non-return valve to permit flow of the compound in one direction and at least one rupturable membrane which is coupled to said bottom wall, wherein said first tubular means is configured to receive an external delivery means at said occlusion means, whereby the membrane may be ruptured without the compound contacting an outside environment, for delivery from said cartridge and direct implantation of said compound in absolutely sterile conditions.