Patent ID: 7897596

Claim:
A compound of formula (I) wherein R 1 is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl or substituted cycloalkyl; R 2 , R 3 , and R 4 are, independently from each other, hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, halogen, hydroxyl, nitro, cyano, alkoxy or substituted alkoxy; Q is selected from the group consisting of in which R 5 is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heteroaralkyl, substituted heteroaralkyl, acyl or substituted acyl; R 6 and R 7 are, independently from each other, hydrogen, C 1 -C 3 alkyl or C 1 -C 3 substituted alkyl; or R 6 and R 7 , provided they are attached to the same carbon atom, combined are alkylene which together with the carbon atom to which they are attached form a 3- to 7-membered spirocyclic ring; R 8 , R 9 , R 10 , R 11 , R 12 and R 13 are, independently from each other, hydrogen, C 1 -C 3 alkyl or C 1 -C 3 substituted alkyl; X is C—H; or X is C—NR 14 R 15 wherein R 14 and R 15 are, independently from each other, hydrogen, C 1 -C 3 alkyl, C 1 -C 3 substituted alkyl, aryl or substituted aryl; or X is C—R 16 wherein R 16 and R 5 combined are a carbonyl oxygen; or X is C—R 16 wherein R 16 and R 5 combined are a divalent radical of the formula ←Y—CHR 17 —(CH 2 ) n —CHR 18 —Y→ which together with the carbon atom to which R 16 and R 5 are attached form a 5- to 7-membered spirocyclic ring, and in which Y is oxygen or sulfur; R 17 and R 18 are, independently from each other, hydrogen, C 1 -C 6 alkyl, C 1 -C 6 substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl or substituted aryl; n is zero, or an integer of 1 or 2; or X is C—R 16 wherein R 16 and R 5 combined are a divalent radical of the formula which together with the carbon atom to which R 16 and R 5 are attached form a 5-membered spirocyclic ring, and in which Y is oxygen or sulfur; R 19 and R 20 are, independently from each other, hydrogen, halogen, cyano, trifluoromethyl, C 1 -C 6 alkyl, C 1 -C 6 substituted alkyl or C 1 -C 6 alkoxy; or a pharmaceutically acceptable salt thereof.