Patent ID: 8163765

Claim:
A compound of formula (A), and N-oxide forms, pharmaceutically acceptable addition salts and stereo-chemically isomeric forms of the compound of formula (A) in which Q is C 1-2 alkyloxycarbonyl, hydroxycarbonyl or tetrahydropyranyloxyaminocarbony; n is 0 or 1 and when n is 0 then a direct bond is intended; m is 0, 1 or 2 and when n is 0 then a direct bond is intended; p is 0 or 1 and when n is 0 then a direct bond is intended; each X is independently N or CH; each Y is independently O, NH, N—C 1-6 alkyl, CH or CH 2 and when Y is CH then the substituent is attached to the Y atom of the ring structure; R 2 is C 1-6 alkyl, C 3-7 cycloalkyl, C 1-6 alkylaminocarbonyl or C 1-6 alkyloxycarbonyl; R 3 is hydrogen, C 1-6 alkyl, C 3-7 cycloalkyl, hydroxyC 1-6 alkyl, C 1-6 alkyloxyC 1-6 alkyl C 1-6 alkyloxycarbonyl or C 1-6 alkylaminocarbonyl; or R 2 and R 3 can be bridged with a methylene, ethylene or propylene bridge thereby forming a cyclic ring system; R 4 is hydrogen, C 1-6 alkyl, —C(═O)—CHR 12 R 13 or —S(═O) 2 —N(CH 3 ) 2 ; wherein each R 12 and R 13 is independently hydrogen, amino, C 1-6 alkyl or aminoC 1-6 alkyl; and R 5 is hydrogen, hydroxy, amino, halo, C 1-6 alkyl, polyhaloC 1-6 alkyl, C 1-6 alkyloxycarbonyl, hydroxycarbonyl, C 1-6 alkylcarbonylamino, C 1-6 alkyloxy, or mono- or di(C 1-6 alkyl)amino