Patent ID: 7939545

Claim:
A compound of the formula (I), wherein: bond a is a double bond and bond b is a single bond or bond a is a single bond and bond b is a double bond; X is NR 1 when bond a is a single bond; or X is N when bond a is a double bond; R 1 is H, (C 1-6 )alkyl, (C 1-6 )haloalkyl, (C 3-7 )cycloalkyl-(C 1-6 )alkyl-, aryl-(C 1-6 )alkyl- or Het-(C 1-6 )alkyl-; wherein each of the (C 1-6 )alkyl, (C 3-7 )cycloalkyl-(C 1-6 )alkyl-, aryl-(C 1-6 )alkyl- and Het-(C 1-6 )alkyl- is optionally substituted with —OH, —O(C 1-6 )alkyl, —SH, —S(C 1-6 )alkyl, —NH 2 , —NH(C 1-6 )alkyl or —N((C 1-6 )alkyl) 2 ; R 2 is H, (C 1-6 )alkyl or —O(C 1-6 )alkyl when bond b is a single bond; or R 2 is O when bond b is a double bond; R 3 is (C 1-6 )alkyl, (C 1-6 )haloalkyl, (C 2-6 )alkenyl, (C 2-6 )alkynyl, (C 3-7 )cycloalkyl-(C 1-6 )alkyl-, aryl-(C 1-6 )alkyl-, Het-(C 1-6 )alkyl- or —Y—R 31 , and bond c is a single bond; or R 3 is (C 1-6 )alkylidene and bond c is a double bond; wherein Y is O or S and R 31 is (C 1-6 )alkyl, (C 1-6 )haloalkyl, (C 2-6 )alkenyl, (C 2-6 )alkynyl, (C 3-7 )cycloalkyl, aryl, (C 3-7 )cycloalkyl-(C 1-6 )alkyl-, aryl-(C 1-6 )alkyl- or Het-(C 1-6 )alkyl-; wherein each of the (C 1-6 )alkylidene, (C 1-6 )alkyl, (C 1-6 )haloalkyl, (C 2-6 )alkenyl, (C 2-6 )alkynyl, (C 3-7 )cycloalkyl-(C 1-6 )alkyl-, aryl-(C 1-6 )alkyl-, Het-(C 1-6 )alkyl- and —Y—R 31 is optionally substituted with 1 to 3 substituents each independently selected from (C 1-6 )alkyl, halo, cyano, oxo and —O(C 1-6 )alkyl; R 4 is aryl or Het, wherein each of the aryl and Het is optionally substituted with 1 to 5 substituents each independently selected from halo, (C 1-6 )alkyl, (C 2-6 )alkenyl, (C 1-6 )haloalkyl, (C 3-7 )cycloalkyl, —OH, —O(C 1-6 )alkyl, —SH, —S(C 1-6 )alkyl, —NH 2 , —NH(C 1-6 )alkyl and —N((C 1-6 )alkyl) 2 ; wherein the (C 1-6 )alkyl is optionally substituted with hydroxy, cyano or oxo; R 6 and R 7 are each independently selected from H, halo, (C 1-6 )alkyl and (C 1-6 )haloalkyl; with the proviso that when bond a is a single bond and bond b is a double bond; and X is NR 1 ; R 1 is H; and R 2 is O; and R 4 is unsubstituted phenyl; R 6 is Cl; R 7 is H; and bond c is a double bond; then R 3 is not ═CH—CH(CH 3 ) 2 ; and wherein Het is a 4- to 7-membered saturated, unsaturated or aromatic heterocycle having 1 to 4 heteroatoms each independently selected from O, N and S, or a 7- to 14-membered saturated, unsaturated or aromatic heteropolycycle having wherever possible 1 to 5 heteroatoms, each independently selected from O, N and S; or a salt, ester or tautomer thereof.