Patent ID: 7652142

Claim:
A compound represented by the structural formula: or a pharmaceutically acceptable salt thereof; wherein: p is 1; M is phenyl; R 1 is selected from the group consisting of: -alkyl-C(O)-heterocyclyl, -haloalkyl-C(O)OR 5 , —S(O 2 )(hydroxyalkyl), -alkyl-C(R 5 )(═N—OR 6 ), and —S(O 2 )(heterocyclyl); R 2 is selected from the group consisting of aryl, and arylalkyl wherein said aryl is phenyl, and said arylalkyl is benzyl or phenethyl; R 3 selected from the group consisting of aryl, 6-membered heteroaryl, and 6-membered heteroaryl-N-oxide, wherein each of said aryl, heteroaryl, and heteroaryl-N-oxide is unsubstituted or independently substituted with 1-4 substituents which can be the same or different each substituent being independently selected from the group consisting of R 11 , R 12 , R 13 and R 14 , wherein said aryl is phenyl, said 6-membered heteroaryl is pyrimidinyl, and said heteroaryl-N-oxide is pyrimidinyl-N-oxide; R 5 and R 6 can be the same or different, each being independently selected from the following group consisting of H, alkyl, cycloalkyl, heterocyclyl, aryl, arylalkyl and heteroaryl; R 9 , R 10 and Z can be the same or different each being independently selected from the group consisting of hydrogen and alkyl; R 11 and R 12 can be the same or different each being independently selected from the group consisting of alkyl, —NR 19 R 20 , and —OH; R 13 is selected from the group consisting of H, —N(R 20 )C(O)N(R 20 R 21 ), —N(H)S(O 2 )alkyl, and —N(H)S(O 2 )cycloalkyl; R 14 is alkyl; R 19 , R 20 and R 21 can each be the same or different and are each independently selected from the group consisting of H, alkyl, aryl, arylalkyl, and cycloalkyl; and A is selected from the group consisting of H, alkyl, and alkenyl.