Patent ID: 7041691

Claim:
A compound having the formula: wherein Ar 1 is a substituted or unsubstituted benzothiazolyl; X is a divalent linkage selected from the group consisting of (C 1 -C 6 )alkylene, (C 1 -C 6 )alkylenoxy, (C 1 -C 6 )alkylenamino, (C 1 -C 6 )alkylene-S(O) k —, —O—, —C(O)—, —N(R 11 )—, —N(R 11 )C(O)—, —S(O) k — and a single bond, wherein R 11 is a member selected from the group consisting of hydrogen, (C 1 -C 8 )alkyl, (C 2 -C 8 )heteroalkyl and aryl(C 1 -C 4 )alkyl; and the subscript k is an integer of from 0 to 2; Y is a divalent linkage selected from the group consisting of alkylene, —O—, —C(O)—, —N(R 12 )—S(O) m —,—N(R 12 )—S(O) m —N(R 13 )—, —N(R 12 )C(O)—, and —S(O) n —, wherein R 12 and R 13 are members independently selected from the group consisting of hydrogen, (C 1 -C 8 )alkyl, (C 2 -C 8 )heteroalkyl and aryl(C 1 -C 4 )alkyl; and the subscripts m and n are independently integers of from 0 to 2; R 1 is a member selected from the group consisting of hydrogen, (C 2 -C 8 )heteroalkyl, aryl, aryl(C 1 -C 4 )alkyl, halogen, cyano, nitro, (C 1 -C 8 )alkyl, (C 1 -C 8 )alkoxy, —C(O)R 14 , —CO 2 R 14 , —C(O)NR 15 R 16 , —S(O) p —R 14 , —S(O) q —NR 15 R 16 , —O—C(O)—OR 17 , —O—C(O)—R 17 , —O—C(O)—NR 15 R 16 , —N(R 14 )—C(O)—NR 15 R 16 ,—N(R 14 )—C(O)—R 17 and —N(R 14 )—C(O)—OR 17 ; wherein R 14 is a member selected from the group consisting of hydrogen, (C 1 -C 8 )alkyl, (C 2 -C 8 )heteroalkyl, aryl and aryl(C 1 -C 4 )alkyl; R 15 and R 16 are members independently selected from the group consisting of hydrogen, (C 1 -C 8 )alkyl, (C 2 -C 8 )heteroalkyl, aryl, and aryl(C 1 -C 4 )alkyl, or taken together with the nitrogen to which each is attached form a 5-, 6- or 7-membered ring; R 17 is a member selected from the group consisting of (C 1 -C 8 )alkyl, (C 2 -C 8 )heteroalkyl, aryl and aryl(C 1 -C 4 )alkyl; the subscript p is an integer of from 0 to 3; and the subscript q is an integer of from 1 to 2; and R 2 is a substituted or unsubstituted aryl; and R 3 is a member selected from the group consisting of halogen, cyano, nitro and (C 1 -C 8 )alkoxy, with the proviso that when Ar 1 is-2-benzothiazolyl, X is S(O) k .