Patent ID: 7078014

Claim:
A method for in vivo MR imaging by intravenous injection of a compound of the formula —(CH 2 ) 2 CONHphenyleneCH 2 DTPA, or where R 9 ═—OR 10 where R 10 is lower alkyl of 1 though 6 carbon atoms; R 2 is —CH 3 , R 5 is —CH 2 CH 3 , and R 3 and R 4 together form a covalent bond or R 2 and R 3 together are ═O, R 4 is —CH 2 CH 3 and R 5 is —CH 3 ; R 6 is —N(R 11 )— or a covalent bond; R 7 is ═O when R 6 is —N(R 11 )— and R 7 is H when R 6 is a covalent bond; and R 8 is —(CH 2 )CO 2 CH 3 , —(CH 2 ) 2 CONHphenyleneCH 2 DTPA, R 11 is lower alkyl of 1 through 6 carbon atoms —(CH 2 ) 2 CONHphenyleneCH 2 DTPA, provided that only one of R 1 , R 8 or R 11 is —(CH 2 ) 2 CONHphenyleneCH 2 DTPA,