Patent ID: 7064128

Claim:
A method to treat pain in a subject which method comprises administering to a subject in need of such treatment a compound of the formula or the salts thereof, wherein Cy represents cyclohexyl and Φ represents phenyl; Y is CH═CHΦ, CHΦ 2 , Φ or Cy, X is trivalent straight-chain alkylene (3–10C) or trivalent straight-chain 1-alkenylene (3–10C) optionally substituted by oxo at the C adjacent N when n is 0 and Y is CHΦ 2 ; and is otherwise trivalent straight-chain alkylene (5–10C) or trivalent straight-chain 1-alkenylene (5–10C) optionally substituted by oxo at the C adjacent N; Z is N, or CHNR 1 wherein R 1 is alkyl (1–6C); and n is 0–5; wherein each Φ and Cy independently may optionally be substituted by alkyl (1–6C) or by halo, CF 3 , OCF 3 , NO 2 , NR 2 , OR, SR, COR, COOR, CONR 2 , NROCR or OOCR where R is H or alkyl (1–4C), or two substituents may form a 5–7 membered ring with the proviso that the compounds of formula (1) contain at least one aromatic moiety.