Patent ID: 8592472

Claim:
A co-crystal of propiconazole with a co-crystal forming compound, wherein said co-forming compound is selected from the group consisting of 2,2′-dihydroxy-1,1′-dinaphthalene, D-ribose, maleic acid, oxalic acid, tartaric acid, terephthalic acid and trimesic acid, and wherein, when the co-crystal forming compound is 2,2′-dihydroxy-1,1′-dinaphthalene, the co-crystal has a powder X-ray diffraction pattern expressed in terms of 2θ angle values, said powder X-ray diffraction pattern comprising at least three 2θ angle values selected from the group comprising (a) 5.9±0.2, 10.2±0.2, 15.2±0.2 and 18.4±0.2 or (b) 5.8±0.2, 8.7±0.2, 10.7±0.2, 15.1±0.2 and 18.1±0.2; when the co-crystal forming compound is D-ribose, the co-crystal has a powder X-ray diffraction pattern expressed in terms of 2θ angle values, said powder X-ray diffraction pattern comprising at least three 2θ angle values selected from the group comprising (a) 7.7±0.2, 8.6±0.2, 13.9±0.2, 18.2±0.2 and 25.0±0.2 or all of the 2θ angles (b) 21.8±0.2, 24.0±0.2 and 26.1±0.2 or (c) 11.3±0.2; when the co-crystal forming compound is maleic acid, the co-crystal has a powder X-ray diffraction pattern expressed in terms of 2θ angle values, said powder X-ray diffraction pattern comprising at least three 2θ angle values selected from the group comprising (a) 7.6±0.2, 10.3±0.2, 16.4±0.2, 18.2±0.2, 19.4±0.2 and 20.2±0.2, (d) 7.6±0.2, 10.4±0.2, 11.8±0.2, 15.4±0.2, 16.1±0.2 and 19.5±0.2 or (e) 5.9±0.2, 7.6±0.2, 10.5±0.2, 15.5±0.2 and 16.2±0.2 or all of the 2θ angle values (b) 5.4±0.2, 10.9±0.2 and 21.1±0.2 or (c) 21.4±0.2 and, 26.1±0.2; when the co-crystal forming compound is oxalic acid, the co-crystal has a powder X-ray diffraction pattern expressed in terms of 2θ angle values, said powder X-ray diffraction pattern comprising at least three 2θ angle values selected from the group comprising 6.7±0.2, 10.3±0.2, 11.1±0.2, 14.9±0.2, 16.3±0.2 and 19.7±0.2; when the co-crystal forming compound is tartaric acid, the co-crystal has a powder X-ray diffraction pattern expressed in terms of 2θ angle values, said powder X-ray diffraction pattern comprising at least three 2θ angle values selected from the group comprising 6.0±0.2, 12.0±0.2, 18.0±0.2 and 24.6±0.2; when the co-crystal forming compound is terephthalic acid, the unit cell parameters are as shown in Table 4B; and when the co-crystal forming compound is trimesic acid, the co-crystal has a powder X-ray diffraction pattern expressed in terms of 2θ angle values, said powder X-ray diffraction pattern comprising 2θ angle values 5.8±0.2, 10.2±0.2 and 16.3±0.2.