Patent ID: 8835513

Claim:
A drug delivery device comprising: a biocompatible biotin-containing component comprising a first polymer selected from the group consisting of polyethylene glycols and absorbable polymers, wherein the biotin-containing component has a molecular weight from about 500 Daltons to about 5000 Daltons; a biocompatible avidin-containing component comprising a polyethylene glycol; and at least one bioactive agent, wherein the absorbable polymer of the first polymer is selected from the group consisting of polycaprolactone, poly-D,L-lactic acid, poly-L-lactic acid, poly(lactide-co-glycolide), poly(hydroxybutyrate), poly(hydroxybutyrate-co-valerate), polydioxanone, polyorthoester, polyanhydride, poly(glycolic acid), poly(glycolic acid-cotrimethylene carbonate), polyphosphoester, polyphosphoester urethane, polyglutamic acid, polyaspartic acid, poly(trimethylene carbonate), poly(iminocarbonate), copoly(ether-esters), polyalkylene oxalates, polyphosphazenes, polyiminocarbonates, aliphatic polycarbonates, and combinations thereof, and wherein the drug delivery device releases the at least one bioactive agent in vivo.