Patent ID: 7781163

Claim:
A G-quadruplex analog polynucleotide comprising the structure: (5′-(L 1 ) q (L 2 ) r (L 3 ) s (L 4 ) t (L 5 ) u (L 6 ) v ) x wherein: each L 1 , L 2 , L 3 , L 4 , L 5 and L 6 is independently selected from the group consisting of a nucleotide, a nucleotide analog, and a nucleotide comprising a 6-methyl-isoxanthopterin nucleobase; q, r, s, t, u and v are each independently 0, 1 or 2, provided that the sum of q+r+s+t+u+v is at least 3; and x is 1 to 8; provided that: 5′-(L 1 ) q (L 2 ) r (L 3 ) s (L 4 ) t (L 5 ) u (L 6 ) v is a analog of a telomeric repeat sequence; said polynucleotide contains at least one nucleotide comprising a 6-methyl-isoxanthopterin nucleobase; said G-quadruplex analog polynucleotide forms a G-quadruplex structure; and wherein each 6-methyl-isoxanthopterin nucleobase is located within said G-quadruplex structure.