Patent ID: 8450502

Claim:
A pharmaceutical composition for treating angiogenesis, comprising: (a) a therapeutically effective amount of an inhibitor of ubiquinone-binding protein (QP-C) of mitochondrial complex III represented by a compound of Formula 1: wherein R 1 to R 12 arc each independently hydrogen, halo, hydroxy, cyano, amino, nitro, nitroso, carboxyl, C 1 -C 12 alkyl, C 2 -C 6 alkenyl, C 3 -C 8 cycloalkyl, C 5 -C 7 cycloalkenyl, C 1 -C 6 alkylamino, alkoxy, aryl, heteroaryl, arylalkyl, arylalkenyl or alkylaryl; R 13 is hydrogen, hydroxy, C 1 -C 12 alkyl or C 1 -C 6 alkoxy; and X is oxygen or sulfur; and (b) a pharmaceutically acceptable carrier.