Patent ID: 8404696

Claim:
A quinazoline-2,4-dione compound of formula (I) wherein R 1 is hydrogen or alkyl; each of R 2 and R 3 is independently selected from hydrogen, alkyl, —COR 6 , —SO 2 R 7 , or substituted or unsubstituted phenyl or benzyl, wherein R 6 is alkyl, alkoxy, phenyl, phenyloxy or benzyloxy, each of which is unsubstituted or substituted with halogen, hydroxy, methoxy, ethoxy or nitro, and R 7 is unsubstituted or substituted lower alkyl or aryl; A is —(CH 2 ) n — or —CH 2 CH═CHCH 2 —, wherein n is an integer selected from 2 to 4; R 4 is hydrogen and R 5 is hydrogen or benzoyl unsubstituted or substituted with one or more of halogen, hydroxy, alkoxy or nitro in benzene ring or when R 4 and R 5 together with N form a ring, R 4 and R 5 form a divalent moiety of wherein R 8 is hydrogen or alkyl; each of l and m is independently an integer selected from 2 to 4; and p is an integer of 0 or 1, or a pharmaceutically acceptable salt thereof.