Patent ID: 6900217

Claim:
A compound of the formula or a pharmaceutically acceptable salt thereof, wherein A is CR 7 ; B is —CHR 1 R 2 , —NR 1 R 2 , —NHCHR 1 R 2 , —OCHR 1 R 2 , or —SCHR 1 R 2 ; R 1 is C 1 -C 6 alkyl which may be optionally substituted with one hydroxy, fluoro, CF 3 or C 1 -C 4 alkyl, which may optionally contain one or two double or triple bond; R 2 is benzyl or C 1 -C 6 alkyl, which may optionally contain one double or triple bond, wherein said C 1 -C 6 alkyl and the phenyl moiety of said benzyl may optionally be substituted with one fluoro, CF 3 , C 1 -C 2 alkyl, C 1 -C 2 alkoxy, or chloro group; R 3 is hydrogen, C 1 -C 4 alkyl, —O(C 1 -C 4 alkyl), chloro, fluoro, bromo, iodo, (C 1 -C 2 alkylene)-O—(C 1 -C 2 alkyl), (C 1 -C 2 alkylene)-OH, or —S(C 1 -C 4 alkyl); n is zero to two; each R is, independently, hydrogen, (C 1 -C 6 alkyl), fluoro, chloro, bromo, iodo, hydroxy, cyano, amino, (C 1 -C 2 alkylene)-OH, CF 3 , CH 2 SCH 3 , nitro, —O(C 1 -C 4 alkyl), —N(C 1 -C 4 alkyl)(C 1 -C 2 alkyl), —S(C 1 -C 4 alkyl), —CO(C 1 -C 4 alkyl), —C(═O)H or —C(═O)O(C 1 -C 4 alkyl); R 5 is phenyl, pyridyl, pyrazinyl, pyrimidyl, pyridazinyl and wherein each of the foregoing R 5 groups is substituted with from one to four R 13 substituents wherein one to three of said R 13 substituents may be selected, independently, from fluoro, chloro, C 1 -C 6 alkyl and —O(C 1 -C 2 alkyl) and one of said R 13 substituents may be selected from bromo, iodo, formyl, OH, (C 1 -C 4 alkylene)-OH, (C 1 -C 4 alkylene)-O—(C 1 -C 2 alkyl), —CN, —CF 3 , —NO 2 , —NH 2 , —NH(C 1 -C 4 alkyl), —N(C 1 -C 2 alkyl)(C 1 -C 6 alkyl), —OCO(C 1 -C 4 alkyl), (C 1 -C 4 alkylene)-O—(C 1 -C 4 alkyl), —S(C 1 -C 6 alkyl), (C 1 -C 4 alkylene)-S—(C 1 -C 4 alkyl), —C(═O)O(C 1 -C 4 alkyl), —C(═O)(C 1 -C 4 alkyl), —COOH, —SO 2 NH(C 1 -C 4 alkyl), —SO 2 N(C 1 -C 2 alkyl)(C 1 -C 4 alkyl), —SO 2 NH 2 , —NHSO 2 (C 1 -C 4 alkyl), —S(C 1 -C 6 alkyl) and —SO 2 (C 1 -C 6 alkyl), and wherein each of the C 1 -C 4 alkyl and C 1 -C 6 alkyl moieties in foregoing R 5 groups may optionally have one or two double bonds; R 7 is hydrogen, C 1 -C 1 alkyl, halo, hydroxy, —O(C 1 -C 4 alkyl, —C(═O)(C 1 -C 4 alkyl), —C(═O)(C 1 -C 4 alkyl), —OCF 3 , —CF 3 , —CH 2 OH or —CH 2 O(C 1 -C 2 alkyl); or the pharmaceutically acceptable salts of such compounds.