Patent ID: 8710264

Claim:
A compound of general formula I wherein Y is selected from —CHR ay —, —CHR ay —CHR by —, —CR ay ═CR by —, —C≡C—, —CHR ay —CHR by —CHR cy —, —CHR ay —CR by ═CR cy —, and —CHR ay —C≡C—; each R ay , R by , and R cy is independently selected from hydrogen, substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl, and substituted or unsubstituted C 2 -C 12 alkynyl; each R 1 , R 2 , R 3 , R 4 , and R 5 is independently selected from hydrogen, substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl, and substituted or unsubstituted C 2 -C 12 alkynyl; R 6 is selected from NR 8 R 9 , and OR 10 ; W is selected from O and NR 7 ; R 7 is selected from hydrogen, COR a , COOR a , substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl, and substituted or unsubstituted C 2 -C 12 alkynyl, or R 7 and R 5 together with the corresponding N atom and C atom to which they are attached may form a substituted or unsubstituted heterocyclic group; R 8 is selected from hydrogen, COR a , COOR a , substituted or unsubstituted C 2 -C 12 alkenyl, substituted or unsubstituted C 2 -C 12 alkynyl, and substituted or unsubstituted C 4 -C 12 alkenynyl; R 10 is selected from substituted or unsubstituted C 2 -C 12 alkenyl, and substituted or unsubstituted C 2 -C 12 alkynyl; each dotted line represents an optional additional bond with the proviso that one or more additional bonds are present, but when a triple bond exists between the C atoms to which R 1 and R 2 are attached, R 1 and R 2 are absent, and when a triple bond exists between the C atoms to which R 3 and R 4 are attached, R 3 and R 4 are absent; R 9 is selected from hydrogen, COR a , COOR a , substituted or unsubstituted C 2 -C 12 alkenyl, substituted or unsubstituted C 2 -C 12 alkynyl, and substituted or unsubstituted C 4 -C 12 alkenynyl; each R 11 , R 12 , R 13 , R 14 , and R 15 are independently selected from hydrogen, halogen, OR a , COR a , COOR a , OCOR a , OCOOR a , OCONR a R b , CONR a R b , OS(O)R a , OSO 2 R a , OP(O)(R a )OR b , OSiR a R b R c , NR a R b , NR a COR b , NR a CONR a R b , NR a S(O)R b , NR a SO 2 R b , NR a C(═NR a )NR a R b , SR a , S(O)R a , SO 2 R a , S(O)NR a R b , SO 2 NR a R b , S(O)OR a , SO 2 OR a , substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl, and substituted or unsubstituted C 2 -C 12 alkynyl; and each R a , R b , and R c are independently selected from hydrogen, substituted or unsubstituted C 1 -C 12 alkyl, substituted or unsubstituted C 2 -C 12 alkenyl, substituted or unsubstituted C 2 -C 12 alkynyl, substituted or unsubstituted aryl and substituted or unsubstituted heterocyclic group; or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof.