Patent ID: 8703808

Claim:
A compound of formula (IV): wherein: Z represents a CH unit; R 4 and R 5 are different from one another, and R 4 represents a hydrogen atom, a nitrile, an ethyne, a (C 1 -C 5 )alkyl or a carboxamide group, and R 5 represents a hydrogen atom, a (C 1 -C 5 )alkyl, a nitrile or a carboxamide group; R 7 represents a hydrogen atom or a (C 1 -C 5 )alkyl group; R 1 , R 2 and R 3 independently represent a hydrogen atom, a halogen, a hydroxyl, an amine, or a radical (C 1 -C 5 )alkoxy, phenyl, benzyloxy, acetate, methylcarbamate, (C 1 -C 10 )alkoxyacetate, said radical optionally substituted by at least one halogen or a (C 1 -C 10 )alkoxy group; R 2 and R 3 optionally form a condensed heterocycle, optionally substituted by a (C 1 -C 5 )alkyl group; Ar represents an aromatic radical selected from the group consisting of: provided that when Ar is (B″) and R 1 , R 3 , R 5 and R 7 represent a hydrogen atom and R 4 represents a nitrile group, then R 2 is not a hydrogen atom; such that the compound of formula (IV) is not (Z)-2-(1H-indol-3-yl)-3-pyridin-3-yl-acrylonitrile, and pharmaceutically acceptable salts thereof.