Patent ID: 7038052

Claim:
A method of preparing a compound of Formula 6 R 1 is hydrogen, hydroxy, halo, cyano, carboxamido, carboalkoxy of two to six carbon atoms, alkyl of 1 to 6 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, or alkanesulfonamido of 1 to 6 carbon atoms; A and D are selected from carbon substituted by R 1 and nitrogen, provided that at least one of A and D is nitrogen; E and G are carbon, substituted by R 1 ; and R″ is benzyl or substituted benzyl, comprising the step of cyclizing a compound of Formula 5 wherein X is Br, Cl or I; with palladium or copper catalyst.