Patent ID: 8858963

Claim:
A pharmaceutical composition for extended release of hydrocodone and acetaminophen, comprising: at least one extended release portion comprising hydrocodone or a pharmaceutically acceptable salt thereof, acetaminophen, and an extended release component; wherein the total amount of acetaminophen in the composition is about 325 mg to about 650 mg, and the total amount of hydrocodone or salt in the composition is about 7.5 mg to about 15 mg; and wherein composition provides an AUC 0-1.27h for acetaminophen of about 3 ng·h/mL/mg to about 13 ng·h/mL/mg; an AUC 1.27-36h for acetaminophen of about 20 ng·h/mL/mg to about 75 ng·h/mL/mg; an AUC 0-2.4h for hydrocodone or salt of about 0.5 ng·h/mL/mg to about 5 ng·h/mL/mg; and AUC 2.4-36h for hydrocodone or salt of about 5 ng·h/mL/mg to about 25 ng·h/mL/mg.