Patent ID: 8263342

Claim:
A method of determining that a pregnant woman has preeclampsia or is at increased risk of developing preeclampsia, comprising: (a) measuring a level of serpina-1 polypeptide and/or albumin polypeptide in a urine sample from the pregnant woman; and (b) comparing the level of serpina-1 polypeptide and/or albumin polypeptide in the urine sample with a reference value, wherein a higher level of serpina-1 polypeptide and/or albumin polypeptide in the urine sample relative to the reference value indicates that the pregnant woman has preeclampsia or is at increased risk of developing preeclampsia, wherein the albumin polypeptide comprises the amino acid sequence set forth as DAHKSEVAHRFKDLGEENFKALVL (SEQ ID NO:5) or DAHKSEVAHRFKDLGEENFKALVLIA (SEQ ID NO:6).