Patent ID: 7115280

Claim:
A particulate coformulation of an active substance and an additive, which is a solid dispersion of one component in the other formed from a co-precipitation process containing a supercritical fluid, whererin each particle contains a particle core having a first concentration by weight of the active substance within a range from about 90% to about 100%, a particle surface having a second concentration by weight of the active substance within a range from about 0% to about 5%, a relative additive concentration increasing radially outwards along a finite gradient and the particles are spherical or approximately spherical particles having a volume mean diameter of less than 100 μm, or needle-like particles having a volume mean length within a range from about 5 μm to about 100 μm and a volume mean thickness within a range from about 0.5 μm to about 5 μm, or plate-like particles having a volume mean thickness within a range from about 0.5 μm to about 5 μm.