Patent ID: 7727522

Claim:
A pseudotyped SIVsmmPBj 14 vector comprising a SIVsmmPBj 14 viral genome in which at least a portion of the SIVsmmPBj 14 env gene is deleted to render the envelope protein encoded by the SIVsmmPBj14 env gene non-expressible, wherein the vector is capable of transducing cells in a G 0 phase, a mitotic phase, and a G 1 phase; and the vector further comprises a gene encoding an envelope protein of a non-SIVsmmPBj14 virus under the control of a promoter; the non-SIVsmmPBj 14 virus selected from the group consisting of HIV-1, SIVagm, SNV, MLV and VSV wherein the non-SIVsmmPBj14 envelope protein is expressed to form the vector envelope.