Patent ID: 8044204

Claim:
A compound of Formula A or a tautomer thereof of Formula B or a pharmaceutically acceptable salt of Formula A or Formula B, wherein R 3 is hydrogen, C 1 -C 6 alkyl, or C 2 -C 6 alkanoyl; and R 7 is a pyrrolidinyl, piperazinyl, morpholinyl, thiomorpholinyl, or azepanyl group substituted with substituted with 0 to 2 substituents independently chosen from or more of (a) and 0 or 1 substituents (b); or R 7 is a group of formula in which R 16 is 0 or 1 or more substituents chosen from amino, hydroxy, chloro, fluoro, methyl, methoxy, trifluoromethyl, and trifluoromethoxy; each of which R 7 is substituted with 0 or 1 or more substituents independently chosen from (a) and 0 or 1 substituents chosen from (b); wherein (a) is chosen from halogen, hydroxy, amino, nitro, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, C 1 -C 2 haloalkyl, and C 1 -C 2 haloalkoxy, and (b) is oxo, amino, cyano, hydroxyC 1 -C 4 alkyl, aminoC 1 -C 4 alkyl, C 1 -C 6 alkylthio, C 2 -C 6 alkanoyl, (mono- or di-C 1 -C 4 alkyl)aminoC 0 -C 4 alkyl, (C 3 -C 7 cycloalkyl)C 0 -C 4 alkyl, (C 3 -C 7 cycloalkyl)aminoC 0 -C 4 alkyl, (C 3 -C 7 cycloalkyl)(C 1 -C 4 alkyl)aminoC 0 -C 4 alkyl, (heterocycloalkyl)C 0 -C 4 alkyl, or (aryl)C 0 -C 4 alkyl, where each of (b) other than oxo and cyano is substituted with 0 to 2 substituents independently chosen from halogen, hydroxy, amino, cyano, nitro, oxo, —COOH, —CONH 2 , C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 1 -C 4 alkoxy, mono- and di-(C 1 -C 4 alkyl)amino, C 1 -C 2 haloalkyl, and C 1 -C 2 haloalkoxy.