Patent ID: 7507414

Claim:
An albumin fusion protein comprising a calcitonin polypeptide fused to an albumin polypeptide, wherein said calcitonin polypeptide is selected from: (a) a full-length calcitonin; and (b) a mature calcitonin; and wherein said albumin polypeptide is selected from: (i) a full-length albumin; (ii) a mature albumin; (iii) a fragment of albumin; (iv) a polypeptide consisting of an amino acid sequence at least 95% identical to mature albumin (SEQ ID NO:18); (v) amino acids 1 to 585 of SEQ ID NO:18; and (vi) amino acids 1 to 387 of SEQ ID NO:18; and further wherein the albumin polypeptide has the ability to prolong the serum half-life of the fused calcitonin polypeptide compared to the unfused calcitonin polypeptide.