Patent ID: 7056925

Claim:
A compound of formula (I) or a therapeutically acceptable salt thereof, wherein X is —N— or —CH—; R 1 is selected from the group consisting of hydrogen, alkoxy, alkyl, amino, carboxy, cyano, halo, hydroxy, and hydroxyalkyl; R 2 is selected from the group consisting of cyano and halo; R 3 is selected from the group consisting of hydrogen, alkoxy, alkyl, amino, aminoalkyl, aminocarbonyl, arylalkyl, cyano, nitro, —CO 2 R 5 , —COR 5 , and —SR 5 ; R 4 is selected from the group consisting of —(CHR 6 ) m OR 7 , and —(CH 2 ) n NR 8 R 9 ; R 5 is selected from the group consisting of hydrogen, alkenyl, alkyl, aryl, arylalkyl, cycloalkyl, and (cycloalkyl)alkyl; R 6 is selected from the group consisting of hydrogen, alkyl, aryl, and heteroaryl; R 7 is selected from the group consisting of hydrogen, alkenyl, alkoxyalkoxyalkyl, alkoxyalkyl, alkoxycarbonylalkyl, alkylsulfanylalkyl, alkynyl, arylalkyl, arylcarbonylalkyl, aryloxyalkyl, arylsulfanylalkyl, cycloalkenyl, (cycloalkenyl)alkyl, cycloalkyl, (cycloalkyl)alkyl, heteroarylalkoxyalkyl, heteroarylalkyl, (heterocyclyl)alkoxyalkyl, and hydroxyalkyl; R 8 and R 9 are independently selected from the group consisting of hydrogen, alkenyl, alkoxyalkyl, alkyl, alkylsulfanylalkyl, alkynyl, aminoalkyl, arylalkyl, cycloalkenyl, (cycloalkenyl)alkyl, cycloalkyl, (cycloalkyl)alkyl, heteroarylalkyl, (heterocyclyl)alkyl, and hydroxyalkyl; m is 0–6; provided that when R 7 is hydrogen m is other than 0; and n is 0–6; provided that when R 8 and R 9 are both hydrogen, n is other than 0.