Patent ID: 7655412

Claim:
A self assembly molecule having an affinity for one or more known targets and suitable for use in formation of a multimeric complex, comprising: an AB 5 -derived self-assembly unit comprising a monomer of the B subunit of an AB 5 toxin able to bind to another AB 5 -derived self assembly unit comprising a monomer of the B subunit of the AB 5 toxin; and an interaction domain fused directly or via a linker to said monomer of the B subunit of the AB 5 toxin so as to enhance binding of the interaction domain to the target; wherein said interaction domain comprises an antibody, antibody fragment, single domain antibody fragment, a single chain polypeptide of a VH or VL region of an antibody, a peptide or protein derived from a binding region of an antibody, or a molecule or binding portion thereof which specifically binds to cell surface receptors.