Patent ID: 8795723

Claim:
A solid, monolithic sustained release pharmaceutical composition, the composition comprising: a. a sustained release matrix comprising a score that permits the composition to be broken along the score to produce at least two subunits each having a new solvent accessible surface where at least one subunit and an intact form of the pharmaceutical composition have dissolution profiles that have a similarity factor of at least 50%, wherein the matrix comprises from about 20% to about 60% by weight of cross-linked high amylose starch; and b. an effective amount of trazodone or a pharmaceutically acceptable salt thereof disposed within the matrix, wherein the composition (i) has a hardness of from about 100 N to about 350 N, (ii) displays substantially the same release kinetics when the composition is broken to create a new solvent accessible surface, and (iii) is in the form of a tablet.