Patent ID: 7382126

Claim:
A method for improving detection of a weakly-sensitive atomic nucleus type in MR spectroscopy, comprising the steps of: subjecting an examination subject, containing a strongly-sensitive atomic nucleus type A and an MR-active, weakly-sensitive atomic nucleus type X, to a MR spectroscopic pulse sequence, including radiating a plurality of RF pulses at respectively different frequencies; in said MR spectroscopic pulse sequence, radiating said plurality of RF pulses in a sequence with respective, predetermined time intervals between successive RF pulses in said sequence, with none of said RF pulses being radiated simultaneously or overlapping one another, to produce a polarization transfer of said strongly-sensitive atomic nucleus type A and said weakly-sensitive atomic nucleus type X by radiating a first A-selective 90 x °A RF pulse for excitation of the strongly-sensitive nucleus type A, radiating a second A-selective 180 x °A RF pulse after a time T 1 after the middle of the first RF pulse, radiating a third X-selective 180 x °X RF pulse after a time T 2 after the middle of the second RF pulse, radiating a fourth A-selective 90 y °A RF pulse after a time T 3 after the middle of the third RF pulse, radiating a fifth X-selective 90 x °X RF pulse after a time T 22 after the middle of the fourth RF pulse, radiating a sixth X-selective 180 x °X RF pulse after a time T 4 after the middle of the fifth RF pulse; and acquiring a magnetic resonance signal as an FID signal from said subject after a time T 5 after the middle of the seventh RF pulse, and electronically analyzing said magnetic resonance signal to obtain MR spectroscopic information therefrom.