Patent ID: 8497376

Claim:
A compound of Formula I: or a tautomer or pharmaceutically acceptable salt thereof, wherein: W is wherein each R 4 is independently H, F, Cl, Br, I, OH, OCH 3 , OCH 2 CH 3 , SC (1-4) alkyl, SOC (1-4) alkyl, SO 2 C (1-4) alkyl, —C (1-3) alkyl, CO 2 R d , CONR e R f , C≡CR g , or CN; wherein R d is H, or —C (1-3) alkyl; R e is H, or —C (1-3) alkyl; R f is H, or —C (1-3) alkyl; and R g is H, —CH 2 OH, or —CH 2 CH 2 OH; R 2 is cycloalkyl, spiro-substituted cycloalkenyl, thiophenyl, dihydrosulfonopyranyl, phenyl, furanyl, tetrahydropyridyl, or dihydropyranyl, any of which may be independently substituted with one or two of each of the following: chloro, fluoro, hydroxy, C( 1-3 )alkyl, and C (1-4) alkyl; Z is H, F, Cl, or CH 3 ; J is CH, or N; X is wherein R w is H, —C (1-4) alkyl, —CO 2 C (1-4) alkyl, —CONH 2 , —CONHC (1-4) alkyl, —CON(C (1-4) alkyl) 2 , or —COC (1-4) alkyl.