Patent ID: 8235966

Claim:
A method for combining at least two distinct chemical species in vivo relative to a target tissue comprising the steps of: placing at least one substantially planar nonconductive sheet conformable to the three-dimensional topography of the surface of the target tissue coincident to the target tissue, the at least one sheet containing a plurality of independently addressable electrode elements; establishing a first chemical staging location; establishing a second chemical staging location; establishing a chemical reaction location; introducing a first chemical species to the first chemical staging location; introducing a second chemical species to the second chemical staging location; applying a controlled voltage between at least three independently addressable electrode elements of the plurality of electrode elements and controlling the current drawn by the electrode elements as a result of the applied voltage to insure that a peak power of less than about 1 kilowatt is delivered to the target tissue; controlling the electrical potential to migrate the first and second chemical species towards the chemical reaction location.