Patent ID: 6919340

Claim:
At least one chemical entity chosen from compounds of Formula 10 and pharmaceutically acceptable salts, hydrates, and diastereomers, wherein R 1 is chosen from phenyl and substituted phenyl, wherein said substituted phenyl is chosen from mono-, di- and trisubstituted phenyls, and wherein substituents are independently chosen from hydroxy, nitro, cyano, amino, sulfonamide, halo, C 1 -C 6 alkyl, C 1 -C 6 perfluoroalkyl, C 1 -C 6 perfluoroalkoxy, C 1 -C 6 alkoxy, mono(C 1 -C 6 alkyl)amino, di(C 1 -C 6 alkyl)amino, mono(C 1 -C 6 alkyl)amino(C 1 -C 6 alkyl), and di(C 1 -C 6 alkyl)amino(C 1 -C 6 alkyl); and R 2 is chosen from phenyl and substituted phenyl, wherein said substituted phenyl is chosen from mono-, di- and trisubstituted phenyls and wherein substitutents are chosen from hydroxy, nitro, cyano, amino, halo, C 1 -C 6 alkyl, C 1 -C 6 perfluoroalkyl, C 1 -C 6 perfluoroalkoxy, C 1 -C 6 alkoxy, (C 1 -C 6 )-alkyl-oxy-(C 1 -C 6 )alkoxy, mono(C 1 -C 6 alkyl)amino, di(C 1 -C 6 alkyl)amino, and amino(C 1 -C 6 alkyl); R 3 is chosen from hydrogen; and straight and branched chain C 1 -C 7 alkyls, in which the branched alkyl chains may form a 3-7 member ring chosen from heteroalkyl rings and alkyl rings; and A is chosen from 0 and 1.