Patent ID: 7592482

Claim:
A process for the preparation of the compound of formula (I) according to the scheme below comprising: reacting N-[2-[(2-aminoethyl)amino]ethyl]-O-(phenylmethyl)serine of formula (II), or a carboxylate alkaline salt thereof, with a compound of formula (III) XCH 2 COOH (III) wherein X is a halogen atom, in the presence of a base, characterised in that: a) in a first step, one or more aliquots of the compound of formula (III) and of the base are added to an aqueous solution of the compound of formula (II), simultaneously, consecutively or alternately, at a temperature ranging from 10° C. to 30° C.; and b) in a second step, the reaction mixture is warmed up to a temperature ranging from 30° C. to 60° C. and, optionally, one or more aliquots of the compound of formula (III) and of the base are added to the reaction mixture, simultaneously, consecutively or alternately, up to completion of the reaction.