Patent ID: 7648988

Claim:
A compound of the formula 1, wherein R 1 denotes pyrrolidin-1-yl; R 2 denotes piperazin-1-yl; R 3 denotes a group of formula 1a, wherein A denotes aryl; X denotes NR 3.2 ; Y denotes C 1-4 -alkylene, substituted by one or more R 3.3 ; m denotes 0, 1 or 2; R 3.1 each independently of one another denote C 1-6 -alkyl, aryl, COOR 3.1.1 , CONR 3.1.1 R 3.1.2 , CN, NR 3.1.1 R 3.1.2 , NHCOR 3.1.1 , OR 3.1.1 , O—C 1-6 -haloalkyl, SO 2 R 3.1.1 , SO 2 NH 2 , halogen, C 1-6 -haloalkyl, C 1-6 -alkyl-CONH 2 , O—C 1-6 -alkyl-NH 2 , O—C 3-6 -cycloalkyl, or O—C 1-4 -alkylene-C 3-6 -cycloalkyl; R 3.1.1 denotes H or C 1-6 -alkyl; R 3.1.2 denotes H or C 1-6 -alkyl; or R 3.1 together with two atoms of A forms a 5- or 6-membered carbocyclic ring or a 5- or 6-membered heterocyclic ring which contains one or more oxygen or nitrogen atoms; R 3.2 denotes H or C 1-6 -alkyl; R 3.3 each independently of one another denote C 1-6 -alkyl, C 1-6 -alkyl-OH, C 3-6 -cycloalkyl, C 3-6 -cycloalkyl-OH, O—C 1-6 -alkyl; or R 3.3 together with one or two carbon atoms of Y forms a carbocyclic ring with 3, 4, 5 or 6 carbon atoms or a pharmacologically acceptable salt thereof.