Patent ID: 7553873

Claim:
A compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein W is —C(O); R 1 is biphenyl optionally substituted with one or more of R 5 or R 6 , and when R 1 is substituted with more than one of R 5 or R 6 , the substituents can be identical or different; R 2 is hydrogen; R 3 is —CO 2 H, —CONHOH, —CONHR 7 , or —COOR 7 ; R 4 is —CONR 9 R 10 ; R 5 is aryl, —NHCO-aryl, —NHCO-heteroaryl, (C 1 -C 6 )alkyl, —O—(C 1 -C 6 )alkyl, or —NHCO—(C 1 -C 6 )alkyl, each alkyl, aryl, or heteroaryl optionally substituted with one or more of R 6 , and when R 5 is substituted with more than one R 6 , the substituents can be identical or different; R 6 is hydrogen, halogen, —CF 3 , —OH, —CO 2 R 7 , —COR 7 , (C 2 -C 6 )alkynyl, (C 2 -C 6 )alkenyl, —O—(C 1 -C 6 )alkyl-(C 3 -C 6 )cycloalkyl, —O—(C 1 -C 6 )alkyl substituted with aryl or O-aryl, each aryl, optionally substituted with one or more of R 13 ; R 12 is aryl optionally substituted with one or more of R 13 ; R 7 is hydrogen or (C 1 -C 6 )alkyl; R 9 is hydrogen or (C 1 -C 6 )alkyl optionally substituted with one or more R 12 ; R 10 is (C 1 -C 6 )alkyl substituted with one or more R 12 ; R 13 is halogen, —O—(C 1 -C 6 )alkyl, —CO 2 H, —OH, —CF 3 , hydrogen, (C 1 -C 6 )alkyl, aryl, heteroaryl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, cycloalkyl, cycloalkyl substituted with —OH, aryl substituted with —NH 2 , aryl substituted with —O—(C 1 -C 6 )alkyl, —(CH 2 ) n -aryl, or —(CH 2 ) n -heteroaryl; m is 0; n is 0-4; and p is 2.