Patent ID: 7585886

Claim:
A pyrrolidine derivative represented by a general formula (I) or a pharmaceutically acceptable salt thereof [signs in the formula have the following meanings; A and B: each independently —C(R 7 )(R 7a )— or —C(O)—, R 7 and R 7a : each independently —H, lower alkyl, aryl or —C(O)OR 0 , R 0 : —H or lower alkyl, X: single bond, *—C(O)—, *—OC(O)—, *—N(R 8 )C(O)— or *—S(O) n —, wherein * represents bonding to R 1 , R 8 : —H, lower alkyl or lower alkylene-aryl, n: 0, 1 or 2, R 1 : —H, or C 1-12 alkyl, lower alkenyl, aryl, hetero ring group or cycloalkyl, which may respectively be substituted, R 2 and R 3 : each independently —H, lower alkyl, halogeno lower alkyl, —OC(O)—R 0 , cycloalkyl, lower alkylene-cycloalkyl, aryl, lower alkylene-aryl, hetero ring group or lower alkylene-hetero ring group, wherein the aryl and hetero ring group in R 2 and R 3 may be substituted respectively, or R 2 and R 3 in combination may form cycloalkyl ring or hetero ring, which may respectively be substituted, together with the carbon atom to which they are bonded, R 4 : aryl or hetero ring group, which may respectively be substituted, R 5 : lower alkyl or halogeno lower alkyl, and R 6 : —H, lower alkyl or halogeno lower alkyl, with the proviso that when R 4 is unsubstituted phenyl, at least one of R 2 and R 3 is not —H].