Patent ID: 7259178

Claim:
A compound of the formula (I): wherein: R 1 is hydrogen, halogen, or lower-alkyl; R 2 is lower-alkyl, fluoro-lower-alkyl, cycloalkyl-lower-alkyl, or heterocyclyl-lower-alkyl; R 3 is hydrogen, lower-alkyl, aryl, cycloalkyl, or heterocyclyl; R 4 is hydrogen, hydroxy, lower-alkoxy, aryl-lower-alkoxy, or heterocyclyl-lower-alkoxy; R 5 is hydrogen, lower-alkyl, aryl, or heterocyclyl; R 6 is R 7 is lower-alkyl or fluoro-lower-alkyl; R 8 is phenyl which is optionally substituted with 1 to 3 substituents selected from the group consisting of hydroxy, amino, halogen, lower-alkyl, fluoro-lower-alkyl, hydroxy-lower-alkyl, R 9 —O—C(O)—, R 10 R 11 NC(O)—, R 12 —O—C(O)-lower-alkyl, R 13 —O—C(O)-hydroxy-lower-alkyl, R 14 R 15 NC(O)-lower-alkyl, R 16 R 17 NC(O)-hydroxy-lower-alkyl, lower-alkoxy, aryl-lower-alkoxy, R 18 —O—C(O)-lower-alkoxy and R 19 R 20 NC(O)-lower-alkyoxy; R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 and R 20 independently from each other are hydrogen or lower-alkyl; L is a single bond, lower-alkylene, or lower-alkenylene; m is 0 to 3; n is 0 or 1; and pharmaceutically acceptable salts and esters thereof.