Patent ID: 8129389

Claim:
A compound of the formula (I) in which A is phenyl or naphthalene, each of which can be substituted by one, two, three or four radicals R 4 which are selected independently of one another from the group consisting of hydrogen, chlorine, bromine, iodine, fluorine, (CH 2 ) 0-2 —CN, CF 3 , OCF 3 , CONH 2 , CONH(C 1 -C 4 -alkyl), CON(C 1 -C 4 -alkyl)(C 1 -C 4 -alkyl), NHCHO, NHCONH 2 , NH(C 0 -C 4 -alkylene)CONH 2 , NH(C 0 -C 4 -alkylene)CONH(C 1 -C 4 -alkyl), NHCOCH 3 , NO 2 , (CH 2 ) 0-2 —OH, O—C 1 -C 6 -alkyl, (CH 2 ) 1-2 —O—C 1 -C 4 -alkyl, O—C 0 -C 4 -alkylene-phenyl, phenyl, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl and C 2 -C 6 -alkynyl, B is an aromatic or partially aromatic monocyclic or bicyclic system which may be composed of 6, 7, 8, 9 or 10 C atom members and which may be substituted by one, two, three or four radicals selected from the group consisting of the radicals R 6 , R 7 , R 8 and R 9 , where R 6 , R 7 , R 8 and R 9 are selected, independently of one another and independently of their respective occurrence, from the group consisting of hydrogen, chlorine, bromine, iodine, fluorine, (CH 2 ) 0-2 —CN, CF 3 , OCF 3 , CONH 2 , CONH(C 1 -C 4 -alkyl), CON(C 1 -C 4 -alkyl)(C 1 -C 4 -alkyl), NHCHO, NH(C 0-4 -alkylene)CONH(C 1 -C 4 -alkyl), NHCOCH 3 , NO 2 , OH, O—C 1 -C 4 -alkyl, (CH 2 ) 0-2 —O—(CH 2 ) 0-3 —CH 3 , O—C 0 -C 4 -alkylene-phenyl, phenyl, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl and C 2 -C 6 -alkynyl; R 1 is CN; R 2 is hydrogen; R 3 is a radical (W)—(X)—(Y)—Z, where W is C 1 -C 4 -alkylene, (C 0 -C 4 -alkylene)-O—(C 0 -C 4 -alkylene) or (C 0 -C 4 -alkylene)-NR 5 —(C 0 -C 4 -alkylene), in which R 5 is hydrogen or C 1 -C 4 -alkyl, X is CO, SO 2 , (C═NH) or (C═N—CN); Y is a radical selected from the group consisting of the radicals Z is a radical selected from the group consisting of the radicals where A 2 and A 3 independently of one another are N or C; A 1 is N, C, O or S; D 1 , D 2 , D 3 , D 4 and D 5 independently of one another are C or N, but where at least one of the variables D 1 , D 2 , D 3 , D 4 and D 5 is N, and where Z may in each case be substituted by the radicals R 12 , R 13 and R 14 , where R 12 , R 13 and R 14 have independently of one another the meanings mentioned below, namely R 12 is hydrogen, chlorine, fluorine CN, CF 3 , OCF 3 , CONH 2 , NHCOCH 3 , NO 2 , OH, O—C 1 -C 4 -alkyl, C 1 -C 4 -alkyl, NH 2 , NH(C 1 -C 4 -alkyl) or N(C 1 -C 4 -alkyl)(C 1 -C 4 -alkyl); R 13 is hydrogen, chlorine, fluorine, OCH, or C 1 -C 4 -alkyl; R 14 is hydrogen; or a tautomeric, enantiomeric or diastereomeric form, or a physiologically tolerated salt of said compound.