Patent ID: 7105552

Claim:
A method of treating diabetes comprising the steps of administering to a subject suffering from a diabetic condition, a therapeutically effective amount of a compound represented by the following formula 1: in a physiologically acceptable carrier; wherein Z is n, m, q and r independently represent integers from zero to 4 provided that n+m<4 and q+r<4; p and s independently represent integers from zero to 5 provided that p+s<5; a and b represent double bonds which may be present or absent; when present, the double bonds may be in the E or Z configuration and, when absent, the resulting stereocenters may have the R— or S— configuration; R and R′ each independently represent a hydrogen atom; linear or branched C 1 -C 20 alkyl; linear or branched C 2 -C 20 alkenyl; —CO 2 Z′; —CO 2 R′″; —NH 2 ; —NHR′″; —NR 2 ′″; —OH; —OR′″; —CONR 2 ″″; halogen atom; optionally substituted linear or branched C 1 -C 20 alkyl; optionally substituted linear or branched C 2 -C 20 alkenyl; R″ independently represents a hydrogen atom; linear or branched C 1 -C 20 alkyl; linear or branched C 2 -C 20 alkenyl; —CO 2 Z′; —CO 2 R′″; —NH 2 ; —NHR′″, —NR 2 ′″; —OH; —OR′″; halogen atom; optionally substituted linear or branched C 1 -C 20 alkyl; optionally substituted linear or branched C 2 -C 20 alkenyl; R′″ independently represents a linear or branched C 1 -C 20 alkyl; or linear or branched C 2 -C 20 alkenyl; R″″ independently represents a hydrogen atom; optionally substituted C 1 -C 20 alkyl; or optionally substituted C 1 -C 20 alkoxy; Z′ represents a hydrogen atom or a pharmaceutically acceptable counter-ion; A, A′ and A″ each independently represent a hydrogen atom; C 1 -C 20 acylamino; C 1 -C 20 acyloxy; C 1 -C 20 alkanoyl; C 1 -C 20 alkoxycarbonyl; C 1 -C 20 alkoxy; C 1 -C 20 alkylamino; C 1 -C 20 alkylcarboxylamino; carboxyl; cyano; halo; or hydroxy; B, B′ and B″ each independently represent; C 2 -C 20 alkenoyl; aroyl; or aralkanoyl; or A and B jointly, A′ and B′ jointly, or A″ and B″ jointly, independently represent a methylenedioxy or ethylenedioxy group; and X and X′ independently represent >NH, >NR′″, —O—, or —S—.