Patent ID: 8344144

Claim:
A compound of formula I: wherein L is C; M is C; Q is CHR 3 ; U is NR 5 ; V is C═O; the dashed circle which represents optional aromatic bonds is absent; R 1 is aryl or heteroaryl, wherein said aryl and heteroaryl groups are optionally substituted on either the carbon or the heteroatom with one to three substituents independently selected from the group consisting of halo, hydroxyl, cyano, C 1-6 alkyl and heterocyclyl, wherein said alkyl group is optionally substituted with hydroxyl or cyano, and said heterocyclyl group is optionally substituted with halo; R 3 is hydrogen; R 5 is hydrogen, halo, cyano, C 1-6 alkyl, (C 1-6 alkyl)OR 6 , heteroyclyl, CH 2 -heterocyclyl or CH 2 -heteroaryl, wherein said alkyl groups are optionally substituted with one to three substituents independently selected from the group consisting of halo, hydroxyl and NR 6 R 7 , and said heterocyclyl groups are optionally substituted on either the carbon or the heteroatom with C 1-6 alkyl; R 6 is hydrogen or C 1-6 alkyl, wherein said alkyl group is optionally substituted with hydroxyl or C 3-6 cycloalkyl; R 7 is hydrogen or C 1-6 alkyl, wherein said alkyl group is optionally substituted with hydroxyl; or a pharmaceutically acceptable salt thereof.