Patent ID: 7498340

Claim:
A compound of Formula I where: A is saturated or unsaturated straight or branched C 1 -C 8 alkyl, C 3 -C 10 cycloalkyl, straight or branched C 3 -C 10 cycloalkyl-C 1 -C 8 alkyl; n and m are both 1; Y is BCOOX, where B is a residue of an amino acid, X is H, straight or branched C 1 -C 4 alkyl, benzyl or phenyl, substituted in the available positions with at least one group selected from C 1 -C 4 alkoxy, halogen, nitro, amino, C 1 -C 4 alkyl, R 1 is a hydrogen or a —C(R 5 )═N—O—R 4 group, in which R 4 is hydrogen or a straight or branched C 1 -C 5 alkyl or C 1 -C 5 alkenyl group, or a C 3 -C 10 cycloalkyl group, or a straight or branched (C 3 C 10 ) cycloalkyl-(C 1 -C 5 ) alkyl group, or a C 6 -C 14 aryl group, or a straight or branched (C 6 -C 14 ) aryl-(C 1 -C 5 ) alkyl group, or a heterocyclic group or a straight or branched heterocyclic-(C 1 -C 5 ) alkyl group, said heterocyclic group containing at least one heteroatom selected from an atom of nitrogen, optionally substituted with a (C 1 -C 5 ) alkyl group, and/or an atom of oxygen and/or of sulphur; said alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aryl-alkyl, heterocyclic or heterocyclo-alkyl groups may optionally be substituted with one or more groups selected from: halogen, hydroxy, C 1 -C 5 alkyl, C 1 -C 5 alkoxy, phenyl, cyano, nitro, —NR 6 R 7 , where R 6 and R 7 , which may be the same or different, are hydrogen, straight or branched (C 1 -C 5 ) alkyl, the —COOH group or one of its pharmaceutically acceptable esters; or the —CONR 8 R 9 group, where R 8 and R 9 , which may be the same or different, are hydrogen, straight or branched (C 1 -C 5 ) alkyl; or R 4 is a (C 6 -C 10 ) aroyl or (C 6 -C 10 ) arylsulphonyl residue, optionally substituted with one or more groups selected from: halogen, hydroxy, straight or branched C 1 -C 5 alkyl, straight or branched C 1 -C 5 alkoxy, phenyl, cyano, nitro, —NR 10 R 11 , where R 10 and R 11 , which may be the same or different, are hydrogen, straight or branched C 1 -C 5 alkyl; or R 4 is a polyaminoalkyl substituent; or R 4 is a glycosyl substituent; R 5 is hydrogen, straight or branched C 1 -C 5 alkyl, straight or branched C 1 -C 5 alkenyl, C 3 -C 10 cycloalkyl, straight or branched (C 3 -C 10 ) cycloalkyl-(C 1 -C 5 ) alkyl, C 6 -C 14 aryl, straight or branched (C 6 -C 14 ) aryl-(C 1 -C 5 ) alkyl; R 2 and R 3 , which may be the same or different, are hydrogen, hydroxyl, straight or branched C 1 -C 5 alkoxy; and the N1-oxides, the racemic mixtures, their individual enantiomers, their individual diastereoisomers, their mixtures, and pharmaceutically acceptable salts.