Patent ID: 8354408

Claim:
A compound of formula Ib wherein Z is NR 2 or S; A and B are independently absent or substituted or unsubstituted C 1-6 alkylene wherein one or more carbon atoms can be optionally replaced with O, CO, NR 2 , NR 2 CO, CONR 2 , NR 2 SO 2 , SO 2 NR 2 , S and/or S(O) n , wherein n is 1 or 2; R 1 is independently selected from H, substituted or unsubstituted C 1-6 alkyl, substituted or unsubstituted C 2-6 alkenyl, substituted or unsubstituted C 2-6 alkynyl, substituted or unsubstituted C 1-6 alkoxy, OH, halogen, CN, NO 2 , NR 2 R 3 , SO 2 R 3 , SO 2 NR 2 R 3 , CF 3 , OCF 3 , NR 2 SO 2 R 3 , CO 2 R 3 , COSR 3 , CSR 3 , COR 3 , NR 2 , CSR 3 , NR 2 CSR 3 , CONR 2 R 3 , NR 2 COR 3 , NR 2 CONR 2 R 3 , SO 3 R 3 , substituted or unsubstituted C 3-8 cycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heterocyclyl having up to 3 heteroatoms selected from N, O, S and SO 2 ; R is selected from substituted or unsubstituted C 1-6 alkyl, substituted or unsubstituted C 2-6 alkenyl, substituted or unsubstituted C 2-6 alkynyl, substituted or unsubstituted C 1-6 alkoxy, OH, halogen, CN, NO 2 , CO 2 R 3 , CONR 2 R 3 , NR 2 COR 3 , SO 3 R 3 , C 3-8 cycloalkyl, aryl and heterocyclyl having up to 3 heteroatoms selected from N, O, S and SO 2 , each of which may be substituted with up to 3 substituents independently selected from substituted or unsubstituted C 1-6 alkyl, substituted or unsubstituted C 2-6 alkenyl, substituted or unsubstituted C 2-6 alkynyl, substituted or unsubstituted C 1-6 alkoxy, OH, OCF 3 , halogen, CN, NO 2 , NR 2 R 3 , SO 2 R 3 , SO 2 NR 2 R 3 , NR 2 SO 2 R 3 , CO 2 R 3 , COR 3 , NR 2 COR 3 , R 2 NHCO 2 R 3 , CONR 2 R 3 , NR 2 CONR 2 R 3 and substituted or unsubstituted heterocyclyl having up to 3 heteroatoms selected from N, O, S and SO 2 ; R 2 and R 3 are independently selected from H, substituted or unsubstituted C 1-6 alkyl, substituted or unsubstituted C 2-6 alkenyl, substituted or unsubstituted C 2-6 alkynyl, substituted or unsubstituted C 1-6 alkoxy, CN, substituted or unsubstituted C 3-8 cycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heterocyclyl having up to 3 heteroatoms selected from N, O, S and SO 2 ; and m is 1 to 3; and salts and/or stereoisomers thereof.