Patent ID: 8268812

Claim:
A compound of Formula (II) wherein L has the following structure X is CR 5 or N; Y is CR 6 or N; Z is a C 1-4 alkylene group, a C 2-4 alkenylene group, a C 2-4 alkynylene group or a C 1-4 heteroalkylene group; each of which may be substituted by one or more hydroxy or amino groups; b is 1, 2 or 3; c is 1, 2 or 3; R 1 is H, F, Cl, Br, I, OH, NH 2 , an alkyl group or a heteroalkyl group; R 2 is H, F or Cl; R 3 is an ethyl, a 2-propyl, a C3-C6 cycloalkyl, a phenyl or a pyridyl group, each of which may be substituted by one, two or more fluorine atoms or amino groups; R 5 is H, F, Cl, OH, NH 2 , an alkyl group or a heteroalkyl group; R 3 and R 5 can be linked via an alkylene, an alkenylene or a heteroalkylene group or be a part of a cycloalkylene or heterocycloalkylene group; in such case R 3 is not H and R 5 is not H, F, OH, NH 2 or Cl; R 6 is H, F, Cl or OMe; R 7 is hydrogen, a group of formula PO 3 R 9 2 or SO 3 R 10 or a heteroalkyl group carrying at least one OH, NH 2 , SO 3 R 10 , PO 3 R 9 2 , or COOH group, wherein R 9 is H, alkyl, cycloalkyl, aryl, or aralkyl, and wherein R 10 is H, alkyl, cycloalkyl, aryl, or aralkyl; R 8 is a group of the formula —CH 2 NHCOMe; or a pharmacologically acceptable salt, solvate, hydrate or formulation thereof.