Patent ID: 8420669

Claim:
A method of treating a pulmonary disease in a mammal comprising administering to the mammal a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I): wherein: R 1 together with R 2 form the group —NH—C(O)—CH═CH—, wherein the nitrogen atom is bound to the carbon atom in the phenyl ring holding R 1 and the carbon atom is bound to the carbon atom in the phenyl ring holding R 2 ; R 3 is chosen from a hydrogen atom, halogen atoms, —SO—R 5 , —SO 2 —R 5 , —NH—CO—NH 2 , —CO—NH 2 , hydantoin, C 1-4 alkyl, C 1-4 alkoxy and —SO 2 NR 5 R 6 ; R 4 is chosen from a hydrogen atom, halogen atoms and C 1-4 alkyl groups; R 5 is chosen from C 1-4 alkyl groups and C 3-8 cycloalkyl groups; R 6 is chosen from a hydrogen atom and C 1-4 alkyl groups; n, p and q are each independently 0, 1, 2, 3 or 4; m and s are each independently 0, 1, 2 or 3; and r is 0, 1 or 2; with the provisos that: at least one of m and r is not 0 the sum n+m+p+q+r+s is 7, 8, 9, 10, 11, 12 or 13 the sum q+r+s is 2, 3, 4, 5 or 6 or a pharmaceutically-acceptable salt or stereoisomer thereof.