Patent ID: 8268861

Claim:
A method for the treatment of multiple sclerosis, Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, neuropathic pain, inflammatory pain, rheumatoid arthritis, osteoporosis, chronic obstructive pulmonary disease, bipolar disorder, schizophrenia, or depression in a patient comprising administering to the patient a therapeutically effective amount of a compound of the general formula: or a pharmaceutically acceptable salt thereof; wherein, R 1 is a mono- or bi-cycloalkylalkyl group or mono- or bi-cycloalkyl group; R 2 is selected from straight or branched C 1 -C 5 alkyl which is optionally substituted by —OH, —CH 2 —OH, C 1 -C 5 alkoxy, NH 2 —, N(R a ) 2 —, NHR a —, CN—, CF 3 , halogen, piperidino, morpholino, pyrrolidino, 5H-tetrazolylpropyl, methylcarbamoyl, dimethylcarbamoyl, and ethylmethylcarbamoyl, wherein R a is C 1 -C 5 alkyl; R 3 , R 4 , R 5 , R 6 , if present, are at each occurrence independently selected from hydrogen, halogen, methyl, methoxy, cyano, and trifluoromethyl; and a, b, c, d, x are at each occurrence independently selected from carbon and nitrogen.