Patent ID: 7264927

Claim:
A method to bind nucleic acids to cellulose, wherein said nucleic acids have not been purified or semi-purified, said method comprising: a) combining cellulose, wherein said cellulose is not chemically coupled or physically adsorbed to another material, with a solution containing said nucleic acids, thereby producing a combination, and b) adjusting the salt and polyalkylene glycol concentrations of the combination to final concentrations suitable for binding the nucleic acids to the cellulose using a binding buffer having a concentration of from 0.5 M to 1.5 M salt and from 5% to 15% polyalkylene glycol, whereby all or a portion of the nucleic acids in the solution binds to the cellulose, and wherein the nucleic acids bind to the cellulose while the nucleic acids are in a non-aggregated state.