Patent ID: 7442378

Claim:
A method for imparting or conferring immunity to circovirus infection in an animal comprising administering to the animal an effective amount of a circovirus vaccine, wherein the vaccine comprises an isolated nucleic acid molecule derived or obtained from a circovirus genome, the nucleic acid molecule including at least a portion of a coding region for viral protein 2 (VP2) of at least 20 nucleotides in length having a mutation therein, wherein the mutation is present in a nucleic acid region encoding amino acid residue 87, 95, 97, 101, 102, 103, 129, 131, 150, 151, 152, or 161 to 170 as set out in SEQ ID NO: 2; or the vaccine comprises an isolated attenuated circovirus capable of cellular replication and having a mutation in viral nucleic acid encoding viral protein 2 (VP2), wherein the mutation is present in a nucleic acid region encoding amino acid residue 87, 95, 97, 101, 102, 103, 129, 131, 150, 151, 152, or 161 to 170 as set out in SEQ ID NO: 2.