Patent ID: 8007752

Claim:
A process for the preparation of an orally administrable calcium composition, said process comprising the steps of: (i) obtaining a physiologically tolerable particulate calcium compound having a mean particle size in the range 3 to 40 μm, having a crystalline structure and having a surface area of 0.1 to 1.2 m 2 /g; (ii) mixing said calcium compound with a water-soluble diluent and a water soluble binder in a fluid bed granulation apparatus and drying the resulting mixture to produce a first granulate, wherein said water-soluble diluent comprises at least one sweetener selected from the group consisting of sorbitol, xylitol, isomalt and mannitol, and wherein said first granulate has a particle size distribution of D(V,0.1=15-21 μm, D(V,0.5)=70-120 μm and D(V,0.9)=190-330 μm; (iii) optionally mixing said first granulate with one or more further components to produce a second granulate; and (iv) optionally compressing said first or second granulate to form tablets.