Patent ID: 8361986

Claim:
An immune modulatory compound selected from the group consisting of 5′-TCG 1 AACG 1 TTCo G -Z- G oCTTG 1 CAAG 1 CT-5′ [5′-SEQ ID NO: 7-3′-Z-3′-SEQ ID NO: 7-5′], 5′-TCG 1 AACG 1 TTCG 1 -Y-TCTTG 1 CTGT C TTG 1 CT-5′ [5′-SEQ ID NO: 18-3′-Y-3′-SEQ ID NO: 172-5′], 5′-TCG 1 AACG 1 TTCG 1 -Y-TCTTG 1 CTG U CT-5′ [5′-SEQ ID NO: 20-3′-Y-3′-SEQ ID NO: 171-5′], 5′-TCG 1 AACG 1 ToTCo G -m- G oCToTG 1 CAAG 1 CT-5′ [5′-SEQ ID NO: 34-3′-m-3′-SEQ ID NO:-34-5′], 5′-TCG 1 AACG 1 TTCo G -Y 2 -GACTTG 2 CTGAC-5′ [5′-SEQ ID NO: 41-3′-Y 2 -3′-SEQ ID NO: 30-5′], 5′-TCG 1 AACG 1 TTCG 1 -Y 3 -TGTTG 1 CTGT C TTG 1 CT-5′ [5′-SEQ ID NO: 45-3′-Y 3 -3′-SEQ ID NO: 178-5′], 5′-TCG 2 TCG 2 TTU 1 Y-M-YU 1 TTG 2 CTG 2 CT-5′ [5′-SEQ ID NO: 12-3′-M-3′-SEQ ID NO: 12-5′], and 5′-CAGTCG 2 TTCAG-Y 2 -TCTTG 1 CTGTCT-5′ [5′-SEQ ID NO: 43-Y 2 -SEQ ID NO: 17-5′] wherein G 1 =7-deaza-dG; G 2 =AraG; G / C / U =2′-O-methylribonucleotides; U 1 =2′-deoxy-U; o=phosphodiester linkage; m=cis,trans-1,3,5-cyclohexanetriol linker; Y=1,3-propanediol linker; Y 2 =1,4-butanediol linker; Y 3 =1,5-pentandiol linker; Z=1,3,5-pentanetriol linker.