Patent ID: 7279550

Claim:
Compounds according to the general formula I or a pharmaceutical acceptable salt thereof, wherein: Y—As—As comprises Benzyl-oxy-carbonyl-Ala-Ala, Z stands for: —CO—CH 2 —W where W can be H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic aryl, heteroaryl, heterocyclic, N 2 , halogen, O-alkyl, O-alkenyl, O-alkynyl, O-carbocyclic, O-aryl, O-heteroaryl, O-heterocyclic, O-acyl, S-alkyl, S-alkenyl, S-alkynyl, S-carbocyclic, S-aryl, S-heteroaryl, S-heterocyclic, S-acyl, C(O)-alkyl, C(O)-alkenyl, C(O)alkynyl, C(O)-carbocyclic, C(O)-aryl, C(O)-heteroaryl, or C(O) heterocyclic residue, or —N + (RR′R″), where R, R′ and R″ are independently from each other an optionally substituted acyl, alkyl, alkenyl, alkynyl, carbocyclic, aryl, heteroaryl, or heterocyclic residue, or —CO—NHO-Q where Q is an optionally substituted acyl, alkenyl, alkynyl, aroyl, carbocyclic, heteroaryl, heterocyclic, aryl, or alkyl residue, or —CR 1 =CR 2 -EWG where R 1 and R 2 are independently from each other H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic, heteroaryl, heterocyclic, or aryl residue, and are in cis or trans position to each other; and where EWG represents an electron-withdrawing group including OR 4 , where R 4 can be H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic, heteroaryl, heterocyclic or aryl residue, or C(O)O—R 5 where R 5 can be H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic, heteroaryl, heterocyclic, acyl, or aryl residue, or CH 2 O—R 6 where R 6 can be H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic, heteroaryl, heterocyclic, acyl or aryl residue, or CN, or SO 2 R 7 where R 7 can be H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic, heteroaryl, heterocyclic, acyl or aryl residue, or PO 2 OR 8 where R 8 can be H, an optionally substituted alkyl, alkenyl, alkynyl, carbocyclic, heteroaryl, heterocyclic, acyl or aryl residue, and pharmaceutically acceptable salts thereof.