Patent ID: 7833979

Claim:
A composition of matter of the formula (X 1 )a—(F 1 )d—(X 2 )b—(F 2 )e—(X 3 )c or multimers thereof, wherein: F 1 and F 2 are half-life extending moieties, and d and e are each independently 0 or 1, provided that at least one of d and e is 1; X 1 , X 2 , and X 3 are each independently -(L) f -P-(L) 9 -, and f and g are each independently 0 or 1; P is a ShK peptide analog of no more than about 80 amino acid residues in length, comprising the amino acid sequence of SEQ ID NO: 914, SEQ ID NO: 915, SEQ ID NO: 916, or SEQ ID NO: 917, and comprising at least two intrapeptide disulfide bonds; L is a linker; and a, b, and c are each independently 0 or 1, provided that at least one of a, b and c is 1; or a physiologically acceptable salt thereof.