Patent ID: 7253193

Claim:
A compound according to formula I wherein X 1 is a straight, branched and/or cyclic hydrocarbon diradical, optionally substituted with one or more hydroxy, halogen, nitro, amino or cyano; X 2 is a bond; a straight, branched and/or cyclic hydrocarbon diradical, optionally substituted with one or more hydroxy, halogen, nitro, amino, cyano, aminosulfonyl, alkylsulfonylamino, alkylcarbonyl, formyl, aminocarbonyl or alkylcarbonylamino; a heteroarylene or non-aromatic heterocyclic hydrocarbon diradical, all of which are optionally substituted with one or more straight, branched and/or cyclic non-aromatic hydrocarbon radical, hydroxyl, halogen, amino, nitro, cyano, aminosulfonyl, alkylsulfonylamino, alkylcarbonyl, formyl, aminocarbonyl or alkylcarbonylamino; X 3 is a straight, branched and/or cyclic hydrocarbon diradical, optionally substituted with one or more substituents selected from the group consisting of hydroxy, halogen, nitro, amino, cyano, aminosulfonyl, alkylsulfonylamino, alkylcarbonyl, formyl, aminocarbonyl or alkylcarbonylamino; with the proviso that when R 6 is —NH 2 , X 3 comprises five carbon atoms or more; and with the further proviso that when n is 0 and R 6 is a heterocyclic ring or ring system with 3–10 ring atoms, wherein at least 1 ring atom constitutes an aliphatic amine, X 3 may also be a bond; Y 1 is a bond, O, S, S(O), S(O) 2 , C(O), NH—C(O) or C(O)—NH; Y 2 is a bond, an ether diradical (R′—O—R″), an amine diradical (R′—N—R″), O, S, S(O), S(O) 2 , C(O), NH—C(O), C(O)—NH, SO 2 —N(R′) or N(R′)—SO 2 wherein R′ and R″ are independently straight or branched hydrocarbon diradicals containing up to 4 carbon atoms; Y 3 is O; R 1 is hydrogen or straight, branched and/or cyclic alkyl, optionally substituted with phenyl; or an aromatic hydrocarbon radical; R 2 is hydrogen, or aryl or heteroaryl, both of which are optionally substituted with one or more substituent selected from the group consisting of halogen, trifluoromethyl, hydroxy, C 1-4 alkoxy, nitro, cyano, C 1-4 hydroxyalkyl or C 1-4 alkyl, optionally substituted with halogen, hydroxyl, cyano or nitro; tetrahydropyranyloxy, di-(C 1-4 alkoxy)phosphinoyloxy or C 1-4 alkoxycarbonylamino; R 4 and R 5 are independently hydrogen; a straight, branched and/or cyclic hydrocarbon radical, optionally substituted with halogen, hydroxyl, halogen, amino, nitro or cyano; R 6 is an amino group or a heterocyclic ring or condensed ring system with 3–10 ring atoms, wherein at least 1 ring atom constitutes an aliphatic amine; A is hydrogen, an optionally substituted, straight, branched and/or cyclic hydrocarbon radical, hydroxy, halogen, nitro, cyano, heteroaryl, heteroaralkyl or thiol; n is 0 or 1; and Z − is a pharmaceutically acceptable anion.