Patent ID: 7144908

Claim:
A compound of formula (I) or a salt or solvate thereof, wherein: m is 5; n is 4; R 1 is —X—R 6 ; wherein X is selected from —(CH 2 ) p — and C 2-6 alkenylene; R 6 is selected from R 7 and R 7a are independently selected from hydrogen, C 1-6 alkyl, C 3-7 cycloalkyl, C(O)R 7b , C(O)NHR 7b , phenyl, naphthyl, and phenyl(C 1-4 alkyl)-, and R 7 and R 7a are optionally substituted by 1 or 2 groups independently selected from halo, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, —NHC(O)(C 1-6 alkyl), —SO 2 (C 1-6 alkyl), —SO 2 (phenyl), —CO 2 H, and —CO 2 (C 1-4 alkyl); R 7b is selected from hydrogen, C 1-6 alkyl, C 3-7 cycloalkyl, phenyl, naphthyl, and phenyl(C 1-4 alkyl), and R 7b is optionally substituted by 1 or 2 groups independently selected from halo, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, —NHC(O)(C 1-6 alkyl), —SO 2 (C 1-6 alkyl), —SO 2 (phenyl), —CO 2 H, and —CO 2 (C 1-4 alkyl); R 8 , R 8a , R 9 and R 9a are independently selected from hydrogen, C 1-6 alkyl, C 3-7 cycloalkyl, phenyl, naphthyl, phenyl(C 1-4 alkyl)-, —NR 10a SO 2 R 10 , —NR 10a C(O)NR 10 R 11 , —SO 2 NR 10 R 11 , and C 1-6 alkyl substituted by —CO 2 R 10 or —C(O)NR 10 R 11 ; R 10 R 10a and R 11 are independently selected from hydrogen, C 1-6 alkyl, C 3-6 cycloalkyl, phenyl, and phenyl (C 1-4 alkyl)-; p is an integer from 0 to 6; R 2 is selected from hydrogen, C 1-6 alkyl, C 1-6 alkoxy, phenyl, halo, and C 1-6 haloalkyl; R 3 is selected from hydrogen, hydroxyl, C 1-6 alkyl, C 1-6 alkoxy, phenyl, halo, C 1-6 haloalkyl, —NR 7 CONR 7 R 7a , and —SO 2 NR a R b ; wherein R a and R b are independently selected from hydrogen, C 1-6 alkyl, C 3-6 cycloalkyl, phenyl, and phenyl (C 1-4 alkyl), or R a and R b , together with the nitrogen to which they are bonded, form a 5 membered nitrogen containing ring; and R a and R b are each optionally substituted by one or two groups selected from halo, C 1-6 alkyl, and C 1-6 haloalkyl; and R 4 and R 5 are independently selected from hydrogen and C 1-4 alkyl with the proviso that the total number of carbon atoms in R 4 and R 5 is not more than 4.