Patent ID: 7678366

Claim:
A sustained release therapeutic nail varnish for treating a human for a fungal infection, onychomycoses, psoriasis and/or chronic paronycia of the nail and/or surrounding tissue, comprising: a. an antifungal amount of naftifine or terbinafine; b. a keratolytic agent; c. at least about 3% of a humectant wherein the humectant is sorbitol, glycerol, or a mixture thereof; d. water in an amount of 0.5 to less than about 5% of the varnish solution; e. a hydrophobic methacrylic polymer in an amount of about 8% to about 35% based on the total weight of the non-volatile components; and f. a volatile solvent selected from the group consisting of an alcohol, a ketone, and mixtures thereof in an amount of about 60% to about 90%, relative to the total weight of the composition; wherein the weight ratio of polymer to the antifungal agent is in the range from about 1:0.01 to about 1:0.3, and the weight ratio of polymer to the karatolytic agent is in the range from about 1:0.01 to about 1:1.