Patent ID: 7550970

Claim:
A method of performing two-dimensional Nuclear Magnetic Resonance (NMR) spectroscopy on a hyperpolarized sample, which method comprises the steps of: hyperpolarizing a sample which comprises a first nuclear species (I) and a second nuclear species (S), with the Hamiltonian H=H S +H IS +H I using DNP, wherein the NMR active nuclei receive hyperpolarization and transformation of the sample to a liquid state; performing two-dimensional NMR spectroscopy on the sample and thereby producing at least two NMR spectra with the use of a sequence of rf-pulses, wherein the sequence of rf-pulses comprises at least two rf-pulses on the same nuclei, and wherein the pulse sequence is adapted for a hyperpolarized sample in such a way that it uses a single scan, an efficient trajectory in a t S -t IS plane and produces a square array of observed points in a square portion of a two time space; analyzing the at least two NMR spectra in order to obtain a characterization of the sample.