Patent ID: 6956051

Claim:
An amphiphilic drug-oligomer conjugate comprising a therapeutic compound consisting of an enkephalin compound selected from the group consisting of SEQ ID NOS: 1 or 48 conjugated to an oligomer, wherein the oligomer comprises a lipophilic moiety coupled to a hydrophilic moiety, and wherein the oligomer has the formula: CH 3 (CH 2 ) x (CH 2 CH═CH) y (CH 2 ) z A(OC 2 H 4 ) m (OC 2 H 4 ) n E wherein m=1 to 6; n=0 or 1; x=0, 3 or 6; y=1, 2, 3 or 6; z=2, 3, 7 or 8; A=single bond, CO or CONHCH 2 CH 2 ; and E=OH or OCH 2 COOH.