Patent ID: 7625894

Claim:
A compound of formula I, wherein R 1 , and R 2 are independently hydrogen, lower alkyl, cycloalkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, lower alkyl-amino-lower alkyl, heterocycle-lower alkyl; or R 1 and R 2 can join together to form a N-heterocycle or lower alkyl-N-heterocycle all of which may be unsubstituted or substituted; Y is (R 3 ) n —X— or A(R 3 )(R 3 )C— wherein X is lower alkylene or carbonyl; A is hydroxy; R 3 is lower alkyl, lower alkoxy, amino, hydroxy, heterocyclic, heteroaryl, lower alkyl-heterocycle, heterocycle-lower alkyl, lower alkyl-amino-lower alkyl, heterocycle-lower alkyl-amino, lower alkyl-amino, hydroxy-lower alkyl-amino, amino substituted by lower alkoxy-lower alkyl and lower alkyl; n is 1 or 2; wherein heterocyclic is selected from pyrrolidinyl, tetrahydrothiophenyl, tetrahydrofuranyl, piperidinyl, pranyl, pyrazolidinyl, oxiranyl, dioxanyl, imidazolinyl, imidazolidinyl, morpholinoyl and piperazinyl; cycloalkyl is selected from cyclopropyl, cyclobutyl, cyolopentyl, cyclohexyl, cycloheptyl and cyclooctyl; N-heterocyclic is selected from pyrrolidinyl, imidazolinyl, imidazolidinyl, piperidinyl, morpholinoyl, and piperazinyl; heteroaryl is selected from pyridyl, indolyl, quinoxalinyl, quinolinyl, isoquinolinyl, benzothienyl, benzofuranyl, benzopyranyl, benzothiopyranyl, furanyl, pyrrolyl, thiazolyl, oxazolyl, isoxazolyl, triazolyl, tetrazolyl, pyrazolyl, imidazolyl and thienyl; or a pharmaceutically acceptable salt thereof.