Patent ID: 7365087

Claim:
A method for the treatment or control of bacterial infections in warm-blooded animals which comprises administering to said animal a pharmacologically effective amount of a compound of Formula (I); wherein: X is selected from hydrogen, amino, NR 11 R 12 , alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, vinyl optionally substituted, alkynyl of 2 to 12 carbon atoms optionally substituted and halogen; A″ is a moiety selected from the group: R 11 and R 12 are each independently H or alkyl of 1 to 12 carbon atoms or R 11 and R 12 when optionally taken together with the nitrogen atom to which each is attached form a 3 to 7 membered saturated hydrocarbon ring; Y is selected from hydrogen, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, vinyl, alkynyl of 2 to 12 carbon atoms optionally substituted and halogen; R is selected from alkyl of 1 to 12 carbon atoms optionally substituted, alkenyl of 2 to 6 carbon atoms optionally substituted, alkynyl of 2 to 12 carbon atoms optionally substituted, —CH 2 NR 1 R 2 , aryl of 6, 10 or 14 carbon atoms optionally substituted, aralkyl of 7 to 16 carbon atoms optionally substituted, aroyl of 7 to 13 carbon atoms optionally substituted, SR 3 , heteroaryl of 5 or 6 ring atoms optionally substituted, containing 1 to 4 heteroatoms which may be the same or different, independently selected from nitrogen, oxygen and sulfur, and heteroarylcarbonyl of 5 or 6 ring atoms optionally substituted containing 1 to 4 heteroatoms which may be the same or different, independently selected from nitrogen, oxygen and sulfur; R 1 and R 2 are each independently H or alkyl of 1 to 12 carbon atoms or R 1 and R 2 when optionally taken together with the nitrogen atom to which each is attached form a 3 to 7 membered saturated hydrocarbon ring; R 3 is alkyl of 1 to 12 carbon atoms optionally substituted, —CH 2 -aryl optionally substituted, aralkyl of 7 to 16 carbon atoms optionally substituted, aroyl, —CH 2 (CO)OCH 2 aryl optionally substituted, —CH 2 -alkenyl of 2 to 12 carbon atoms optionally substituted, and —CH 2 -alkynyl of 2 to 12 carbon atoms optionally substituted; with the proviso that when X is NR 11 R 12 and R 11 is hydrogen, then R 12 is methyl, ethyl, n-propyl, n-butyl, 1-methylethyl, 1-methylpropyl, 2-methylpropyl or 1,1-dimethylethyl; and that when R 11 is methyl or ethyl then R 12 is methyl, ethyl, n-propyl, 1-methylethyl, n-propyl, 1-methylpropyl, or 2-methylpropyl; or a tautomer or a pharmaceutically acceptable salt thereof.