Patent ID: 8017621

Claim:
A method of treating a KIT dependent disease in a patient, which comprises: (a) identifying a mutant form of KIT associated with the KIT dependent disease and that is inhibited by Compound A, wherein the mutant form of KIT is selected from D816F, D816H, D816N, D816Y, D816V, K642E, Y823D, Del 550-558, Del 557-561, N822K, V654A, N822H, Del 550-558+V654A. Del 557-561+V654A, Ins503AY, V560G, 558NP, Del 557 558, Del W559-560, F522C, Del 579, R634W, K642E T8011, C809G, D820Y, N822K, N822H, Y823D, Y823C and T6701: and (b) administering to said patient an effective mutant KIT inhibiting amount of compound A, wherein the mutant form of KIT is activated independently of its ligand.