Patent ID: 8053439

Claim:
A compound represented by the following formula 1, a pharmaceutically acceptable salt thereof: wherein, R 1 , R 2 , R 3 , R 4 , and R 5 may be identical to or different from each other, may form a dioxane or dioxolane ring by connecting with adjacent carbons; wherein, R 1 , R 3 and R 5 are each independently hydrogen, hydroxyl, hydroxyalkyl, fluoro, bromo, chloro, substituted or unsubstituted C 1-6 alkyl, C 1-3 alkoxy, formyl, [1,3]dioxane, or a functional group represented by the following structural formula 1, R 2 and R 4 are each independently hydroxyl, hydroxyalkyl, fluoro, bromo, chloro, substituted or unsubstituted C 1-6 alkyl, C 1-3 alkoxy, formyl, [1,3]dioxane, or a functional group represented by the structural formula 1; wherein, q is 1 or 2, and R 6 and R 7 are each independently hydrogen or C 1-3 alkyl; Z is O; X is C or N, provided that when X is C, Rb is hydrogen, C 1-3 alkoxy, substituted or unsubstituted C 1-6 alkyl, or a functional group represented by the structural formula 1, and when X is N, Rb does not exist; Ra is fluoro, —CONH 2 , —COOH, nitro, —O—R 9 (wherein, R 9 is hydrogen, substituted or unsubstituted C 1-6 alkyl, phenyl, —SO 2 —R 10 , or —CO 2 R 10 , wherein R 10 is substituted or unsubstituted C 1-6 alkyl, or substituted or unsubstituted phenyl), —CO—R 10 or —COO—R 10 (wherein, R 10 is the same as defined above), or a functional group represented by the following structural formula 3, wherein, R 11 and R 12 are each independently hydrogen, formyl, C 1-3 alkoxy, pyridine, pyrimidine, substituted or unsubstituted C 1-6 alkyl, hydroxyalkyl, —CO—R 10 , —COO—R 10 , or —SO 2 —R 10 , wherein R 10 is the same as defined above, or a C 5 or C 6 heterocyclic ring containing at least one hetero atom selected from the group consisting of O, S, and N (the ring may not have a substituent, or may be arbitrarily substituted with at least one of substituted or unsubstituted C 1-6 alkyl, C 1-3 alkoxy, thiol, amino, nitro, thiomethyl, carboxylic acid, methylcarboxylate, —CF 3 , or —NR 13 R 14 , wherein R 13 and R 14 are each independently hydrogen, substituted or unsubstituted C 1-6 alkyl, hydroxyalkyl, CO—R 10 , —COO—R 10 , or —SO 2 —R 10 , wherein R 10 is the same as defined above); Rc and Rd are each independently hydrogen, a C 5 or C 6 heterocyclic ring containing at least one hetero atom selected from the group consisting of O, S, and N (the ring may not have a substituent, or may be arbitrarily substituted with at least one of substituted or unsubstituted C 1-6 alkyl, C 1-3 alkoxy, or —NR 13 R 14 , wherein R 13 and R 14 are the same as defined above, and the ring may not have two oxygen), or a R 15 -substituted phenyl (wherein, R 15 is hydroxyl, nitro, substituted or unsubstituted C 1-6 alkyl, C 1-3 alkoxy, fluoro, nitrile, —NR 11 R 12 , —COO—R 10 , or —SO 2 —R 10 , wherein R 10 , R 11 , and R 12 are the same as defined above), provided that Rc and Rd may not be hydrogen simultaneously; and Re is hydrogen or halogen.