Patent ID: 7578845

Claim:
A structured composite as support for tissue engineering and implant material of bones comprising a mass of individual porous calcium phosphate granules, said composite comprising granules having a particle size of from 2 to 10 mm with macropores and micropores, where the macropores have an average diameter of from 50 to 500 μm and the micropores have an average diameter from 0.5 to 5 μm, and a collagen as a biocompatible binder, wherein said individual calcium phosphate granules are uniformly distributed in a collagen fabric formed by the collagen binder, wherein the composite cannot be compressed by pressure from adjacent connective tissue, wherein the composite is obtained by a process comprising the steps of deep-freezing, thawing and subsequent freeze-drying of a mixture comprising said calcium phosphate granules and a suspension of the collagen binder, and wherein the resulting structured composite comprises from 98 to 99 percent by weight of calcium phosphate and from 1 to 2 percent by weight of the collagen binder.