Patent ID: 8163289

Claim:
A method for inducing an immune response in an animal comprising one or more administrations of one or more compositions comprising a polypeptide where the compositions may be the same or different if there is more than one administration and the polypeptide consists of an Fc region linked to two arms; wherein the Fc region consists of two Fc amino acid chains; each Fc amino acid chain is linked to one of the two arms; each arm consists of an HCH2 polymer linked to an antigen portion; the HCH2 polymer consists of two to six linear copies of an HCH2 monomer; the HCH2 monomer consists of at least a fragment of an HCH2 region, wherein the at least a fragment of an HCH2 region includes a hinge region; and at least one hinge region cysteine of the HCH2 monomer is mutated to serine.