Patent ID: 8354441

Claim:
A compound of formula I wherein R a is hydrogen or lower alkyl; R 1 is R 8 is hydrogen, halogen or aryl optionally substituted by halogen; X is, —(CH 2 ) n —, —CHRCH 2 , R is lower alkyl or lower alkyl substituted by halogen; R 2 is a) heterocycloalkyl, optionally substituted by halogen or lower alkyl substituted by halogen; or b) (CR′R″) m -heteroaryl, optionally substituted by halogen, lower alkoxy, lower alkyl substituted by halogen, lower alkoxy substituted by halogen, lower alkyl, cycloalkyl, NHC(O)-lower alkyl, cyano, S(O) 2 -lower alkyl, NR 6 R 7 , or by heteroaryl or heterocycloalkyl each of which is optionally substituted by halogen; R′ and R″ are each independently hydrogen, lower alkoxy or lower alkyl; or together with the C-atom to which they are attached form a cycloalkyl group; R 5 is hydrogen, lower alkyl or aryl substituted by halogen: R 6 and R 7 are each independently hydrogen, lower alkyl or (CH 2 ) 2 —O-lower alkyl; m is 0, 1 or 2; and n is 1, 2 or 3; or a pharmaceutically suitable acid addition salt thereof.