Patent ID: 8394323

Claim:
A method for forming a biochip with a three-dimensional mesoporous layer, comprising: providing a precursor solution that comprises an ionic liquid and at least one alkoxide monomer and/or aryloxide monomer wherein said ionic liquid is formed by mixing an organic base with a Lewis acid that is not halogenated acid and the weight of said ionic liquid is about 10%˜90% weight of said at least alkoxide monomer and/or aryloxide monomer; performing a coating process to coat said precursor solution on a substrate to form an early stage gel; performing a gelation process to form a three-dimensional mesoporous layer by having an alcohol contact with said early stage gel formed by said precursor solution on said substrate, so as to form a composite membrane with a three-dimensional mesoporous layer; performing a cleaning process by a solvent to remove said ionic liquid in said three-dimensional mesoporous layer from said composite membrane; performing a drying process to remove the solvent in said three-dimensional mesoporous layer from said composite membrane; and performing a surface modification process for said three-dimensional mesoporous layer, so as to form a biochip with a three-dimensional mesoporous layer.