Patent ID: 7638551

Claim:
A method for the treatment of an immunology-related disease selected from the group consisting of Crohn's disease, ulcerative colitis, multiple sclerosis, atopic dermatitis, insulin dependent diabetes mellitus, glomerular nephritis and rejection of a transplanted organ or transplanted skin, in a mammal in need thereof which comprises administering to said mammal a pharmaceutically effective amount of a compound, a pharmacologically acceptable salt of the compound or a pharmacologically acceptable ester of the compound, wherein the compound is a compound having a formula (Ia) wherein R 1 and R 2 are each a hydrogen atom; R 3 is a hydrogen atom; R 4 is a C 1 -C 2 alkyl group; n is 2; X is ═N—D, wherein D is a hydrogen atom, a C 1 -C 4 alkyl group or a phenyl group; Y is an ethylene group, an ethynylene group, a group of a formula CO—CH 2 or a phenylene group; Z is an ethylene group or a trimethylene group; R 5 is an unsubstituted C 3 -C 10 cycloalkyl group, an unsubstituted C 6 -C 10 aryl group, or a C 3 -C 10 cycloalkyl group or a C 6 -C 10 aryl group substituted with from 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halogeno lower alkyl group and a lower alkoxy group; and R 6 and R 7 are each a hydrogen atom.