Patent ID: 8263622

Claim:
A fused ring derivative represented by the formula: wherein X 1 and X 2 independently represent CH or N; ring U represents C 6 aryl or 5 or 6-membered heteroaryl; m represents an integral number from 0 to 2; n represents an integral number from 0 to 3; R 1 represents a hydroxy group, a halogen atom, amino or C 1-6 alkyl, and when m is 2, two R 1 are optionally different from each other; R 2 represents any of (1) to (11): (1) a halogen atom; (2) a hydroxy group; (3) cyano; (4) nitro; (5) carboxy; (6) carbamoyl; (7) amino; (8) C 1-6 alkyl, C 2-6 alkenyl or C 1-6 alkoxy each of which may independently have any group selected from substituent group α; (9) C 2-6 alkynyl, C 1-6 alkylsulfonyl, mono(di)C 1-6 alkylsulfamoyl, C 2-7 acyl, C 1-6 alkoxycarbonyl, C 1-6 alkoxycarbonyloxy, mono(di)C 1-6 alkylamino, mono(di)C 1-6 alkoxy C 1-6 alkylamino, C 1-6 alkoxy C 1-6 alkyl(C 1-6 alkyl)amino, C 2-7 acylamino, C 1-6 alkoxycarbonylamino, C 1-6 alkoxycarbonyl(C 1-6 alkyl)amino, mono(di)C 1-6 alkylcarbamoyl, mono(di)C 1-6 alkoxy C 1-6 alkylcarbamoyl, C 1-6 alkoxy C 1-6 alkyl(C 1-6 alkyl)carbamoyl, mono(di)C 1-6 alkylaminocarbonylamino, C 1-6 alkylsulfonylamino or C 1-6 alkylthio; (10) C 3-8 cycloalkyl, 3 to 8-membered heterocycloalkyl, C 5-8 cycloalkenyl or 5 to 8-membered heterocycloalkenyl; (11) C 6 aryl, C 6 aryloxy, C 6 arylcarbonyl, 5 or 6-membered heteroaryl, 5 or 6-membered heteroaryloxy, 5 or 6-membered heteroarylcarbonyl, C 6 arylamino, C 6 aryl(C 1-6 alkyl)amino, 5 or 6-membered heteroarylamino or 5 or 6-membered heteroaryl(C 1-6 alkyl)amino; and when n is 2 or 3, these R 2 are optionally different from each other, and when two R 2 bound to the neighboring atoms exist and independently represent C 1-6 alkyl or C 1-6 alkoxy each of which may have C 1-6 alkoxy, these two R 2 optionally form a 5 to 8-membered ring together with the binding atoms; substituent group α consists of a fluorine atom, a hydroxy group, amino, carboxy, C 1-6 alkoxy, mono(di)C 1-6 alkylamino, mono(di)C 1-6 alkoxy C 1-6 alkylamino, C 1-6 alkoxy C 1-6 alkyl(C 1-6 alkyl)amino, C 1-6 alkoxycarbonylamino, C 2-7 acyl, C 1-6 alkoxycarbonyl, mono(di)C 1-6 alkylcarbamoyl, mono(di)C 1-6 alkoxy C 1-6 alkylcarbamoyl, C 1-6 alkoxy C 1-6 alkyl(C 1-6 alkyl)carbamoyl, C 1-6 alkylsulfonylamino, C 2-7 acylamino, C 1-6 alkoxycarbonylamino, C 3-8 cycloalkyl, 3 to 8-membered heterocycloalkyl, C 6 aryl and 5 or 6-membered heteroaryl, or a pharmaceutically acceptable salt thereof.