Patent ID: 8877798

Claim:
A compound of the following formula II: and enantiomers and pharmaceutically acceptable salts thereof, wherein: R 1 and R 2 are independently selected from hydrogen, unsubstituted C 1-10 alkyl, C 3-10 alkenyl and C 3-10 alkynyl, and substituted C 1-10 alkyl, C 3-10 alkenyl and C 3-10 alkynyl wherein the substituent is one or more of hydroxy, cyano, halogen, C 1-6 alkoxy, aryl substituted C 1-6 alkoxy, aryloxy, aryloxy substituted with one or more halogens, C 1-6 alkyl, C 1-6 alkyl independently substituted with one or more of cyano and halogen, C 1-4 alkoxy, and C 1-4 haloalkoxy; R 3 is selected from hydrogen, C 1-6 alkyl, C 1-6 alkoxycarbonyl, C 2-6 alkanoyl, C 3-8 cycloalkyl, C 4-9 cycloalkanoyl, aryl, heteroaryl, saturated heterocyclic, C 2-10 alkenyl, C 2-10 alkynyl, and substituted C 1-6 alkyl, C 2-10 alkenyl and C 2-10 alkynyl wherein the substituent is one or more of cyano, halogen, hydroxy, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, C 2-6 alkyloxycarbonyloxy, C 1-6 alkanoyl, C 1-6 alkanoyloxy, C 3-8 cycloalkyl, C 3-8 cycloalkyloxy, C 4-9 cycloalkanoyl, aryl, aryloxy, heteroaryl and saturated heterocyclic; and R 4 and R 5 are independently hydrogen or 1-4 substituents independently selected from halogen, C 1-3 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, halo(C 1-3 )alkyl, cyano, hydroxy, C 3-5 cycloalkyl, C 1-3 alkoxy, C 1-3 alkoxy(C 1-3 )alkyl, carboxy(C 1-3 )alkyl, C 1-3 alkanoyl, halo(C 1-3 )alkoxy, nitro, amino, C 1-3 alkylamino, and di(C 1-3 )alkylamino.