Patent ID: 7087765

Claim:
A compound of Formula VIII: wherein: Z is selected from the group consisting of —CH 2 CH 2 —, —CH 2 CH(CH 3 )—, —CH═CH—, —O—CH 2 —, —S—CH 2 —, —O—, and —S—; X 1 and X 2 are independently selected from the group consisting of —F, —CH 3 , —OH, and lower O-alkyl in the 1-, 3-, 7-, or 9-substituent positions; m can be 1 or 2; —NHR is selected from the group consisting of —NH 2 , —NHCH 3 , and —NHC 2 H 5 ; R 1 is selected from the group consisting of —H, alkyl, hydroxyalkyl, —OH, —O-alkyl, and —O-acyl; R 2 is selected from the group consisting of —H, alkyl, hydroxyalkyl; and pharmaceutically acceptable salts and complexes thereof; wherein the compound is active at an NMDA receptor.