Patent ID: 7939255

Claim:
A diagnostic method for prognostic assessment of colorectal cancer, comprising the steps of: (a) obtaining a nucleic acid sample from a colon tissue sample obtained from a human subject; (b) identifying a recurrently altered region (RAR) on a chromosome in said nucleic acid sample by array CGH; (c) detecting variation of expression of a specific gene in the RAR in said nucleic acid sample; and (d) performing prognostic assessment of colorectal cancer in the human subject based on the detected variation, wherein loss of a recurrently altered region (RAR) in step (b) and a reduced expression level of the specific gene compared to a reference from normal colon tissue indicates a poor prognosis of colorectal cancer; wherein the RAR in step (b) is the chromosome region 1p36.31-1p36.23; wherein the specific gene in step (c) is CAMTA1; and wherein poor prognosis of colorectal cancer is defined by poor survival time.