Patent ID: 7241812

Claim:
A compound of Formula IV: wherein: L is alkoxy, a covalent bond, substituted or unsubstituted alkyl, alkylcarbonyl, thioether, alkylsulfonyl, alkylcarbonylamino, alkylaminocarbonyl, alkyloxycarbonyl, alkylcarbonyloxy, or substituted or unsubstituted heteroaryl; Z and A are each independently substituted or unsubstituted aryl, wherein Z and A may be linked by a covalent bond, substituted or unsubstituted alkyl, NH, alkyloxy, O, thioether, S, aminocarbonyl, carbonylamino, carbonyloxy, or oxycarbonyl; R 1 , R 2 , R 5 and R 12 are each independently selected from the group consisting of hydrogen, halogen, cyano, substituted or unsubstituted aryl, straight chain or branched substituted or unsubstituted C 1 –C 6 -alkyl, straight chain or branched substituted or unsubstituted C 1 –C 6 -alkoxy, straight chain or branched halo-C 1 –C 6 -alkyl, straight chain or branched halo-C 1 –C 6 -alkoxy, C 1 –C 6 -alkoxy-C 1 –C 6 -alkyl, hydroxyl-C 1 –C 6 -alkyl, carboxy-C 1 –C 6 -alkyl, C 1 –C 6 -alkyl-SO 2 or N(R)R′, wherein R and R′ are each independently hydrogen, straight chain or branched substituted or unsubstituted C 1 –C 6 -alkyl, straight chain or branched substituted or unsubstituted C 1 –C 6 -alkoxy, straight chain or branched halo-C 1 –C 6 -alkyl, straight chain or branched halo-C 1 –C 6 -alkoxy, C 1 –C 6 -alkoxy-C 1 –C 6 -alkyl, hydroxyl-C 1 –C 6 -alkyl, carboxy-C 1 –C 6 -alkyl or C 1 –C 6 -alkyl-SO 2 ; Q is —NH(CO)—; R 6 is —OPO 3 R 10 R 11 , where R 10 and R 11 are each independently H, straight chain or branched substituted or unsubstituted C 1 –C 6 -alkyl, a substituted or unsubstituted aryl group or selected from the prodrugs listed below: R 7 is H, substituted or unsubstituted C 1 –C 6 -alkyl, hydroxy-C 1 –C 6 -alkyl, aryl, or together with R 8 form a C 2 –C 5 -alkylene or a C 2 –C 5 -alkenylene group; R 8 is H or substituted or unsubstituted C 1 –C 6 -alkyl; and m and n are each, independently, an integer from 0 to 3; and pharmaceutically acceptable salts thereof.