Patent ID: 8481522

Claim:
A N-Heterocyclic carbene-platinum complex bearing in trans of the carbene a nitrogen-containing ligand and corresponding to the general formula (I): wherein: R 1 and R 2 each represents, independently of each other, an aryl or aralkyl group, each optionally substituted; a linear or branched C1-C6 alkyl group; a monocyclic C3-C7 cycloalkyl group; or a linear or branched C2-C6 alkenyl group; R′ represents a hydrogen atom; R represents a group chosen from C3-C8 mono- or bicyclic cycloalkyl or heterocycloalkyl groups or an optionally substituted benzyl group; or R and R′ form together with NH a C3-C8 mono- or bicyclic heterocycloalkyl; V represents a nitrogen atom or a C—R 4 radical; R 3 and R 4 each represents, independently of each other, hydrogen or a phenyl group, or R 3 and R 4 form together a C3-C6 alkylene or C3-C6 heteroalkylene radical with one or more nitrogen-based heteroatoms, it being possible for the carbon atoms of the heteroalkylene radical to be modified in the form of a carbonyl radical; and X represents iodine, bromine, chlorine or a nitrato (—ONO 2 ) group; or a pharmaceutically acceptable salt thereof.