Patent ID: 7524885

Claim:
A compound represented by Formula (I): wherein (a) W is C 1 -C 6 alkyl, halogen, optionally substituted aryl, optionally substituted aralkyl or optionally substituted aralkenyl; (b) Cyc is C 3 or C 4 cycloalkyl; (c) p is an integer from 0 to 4; (d) m is 1 or 2; (e) Y is O, S, or NR; (f) X is O, S, NR, or CR 3 R 4 ; (g) R is H, alkyl, aryl, or where i is an integer from 2 to 4; (h) Z is H, alkyl, heterocycle alkyl, cycloalkyl, aryl or optionally substituted C 1 -C 6 alkylcarbonyl or when X is NR and R is or when X is NR, R and Z may be taken together with N to form a nitrogen-containing heterocyclic ring; (i) R 1 is H, alkyl or aryl; (j) R 2 is H, alkyl, aryl or ═O; (k) R 3 and R 4 are, independently, H, alkyl or aryl; or when X is CR 3 R 4 then R 3 and R 4 , taken together with the carbon atom, may form a heterocyclic ring; and (l) n is an integer from 0 to 10, or a pharmaceutically acceptable salt, ester or prodrug thereof, wherein said compound is selected from the group consisting of: 1-methyl-cyclopropanecarboxylic acid, 2-ethoxy-ethyl ester; 2,2,3,3, tetramethyl-cyclopropanecarboxylic acid, 2-ethoxy-ethyl ester; trans-2-methyl-cyclopropanecarboxylic acid, 2-ethoxy-ethyl ester; 2,2-dichloro-1-methyl-cyclopropanecarboxylic acid, 2-ethoxy-ethyl ester; (1S,2S)-2-phenyl-styrl-cyclopropanecarboxylic acid, 2-ethoxy-ethyl ester; 1-(4-methoxy-phenyl )-cyclopropanecarboxylic acid, 2-ethoxy-ethyl ester; 1-phenyl-cyclopropanecarboxylic acid, 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl ester; 1-(1-phenyl-1-cyclopropanecarboxylic acid)-2-(1-phenyl-cyclopropanecarbonyloxy)-ethyl ester; cyclopropane-carboxylic acid, 2-cyclopropanecarbonyloxy-ethyl ester; cyclopropane-1,1-dicarboxylic acid, bis-(2-ethoxy-ethyl) ester; cyclopropanecarboxylic acid, 2-methoxy-ethyl ester; cyclopropanecarboxylic acid,2-(4-methyl-thiazol-5-yl)-ethyl ester; cyclopropanecarboxylic acid-2-morpholin-4-yl-ethyl ester; cyclopropanecarboxylic acid, 5-ethyl-[1,3]-dioxan-5-ylmethyl ester; cyclopropanecarboxylic acid, 2,3-dihydro-benzo(1,4)-dioxin-2-ylmethyl ester; cyclopropanecarbonylsulfanyl-acetic acid methyl ester; cyclopropanecarbothioic acid, S-(2-acetylamino-ethyl) ester; cyclopropanecarbothioic acid, S-furan-2-ylmethyl ester; and 1,2,3,5,6-penta-O-(cyclopropanecarbonyl)-D-glucopyranose.