Patent ID: 8007805

Claim:
A purified chimeric antigen for eliciting an immune response against Hepatitis B virus (HBV) in a host, wherein the chimeric antigen comprises: a polypeptide immune response domain, wherein the immune response domain comprises at least one antigenic portion of an HBV protein selected from the group consisting of HBV S1/S2, HBV S1/S2/S, HBV Core, HBV Core ctm and HBV polymerase; a polypeptide target binding domain, wherein the target binding domain consists of a hinge region, at least a portion of a C H 1 region and a xenotypic Fc antibody fragment comprising at least part of a C H 2 and C H 3 domain; wherein the immune response domain and the target binding domain are linked by peptide linkage; and wherein the chimeric antigen is non-mammalian glycoslyated.