Patent ID: 6936632

Claim:
[α]-Fused pyrrole compounds of formula 1 in which X is CR8R9 or C(O); A is CR10R11 or a bond between X and an atom carrying radicals R6 and R7; one of the radicals R1, R2, R3 is 4-substituted phenyl, the substituent being selected from C 1-4 -alkylthio, C 1-4 -alkylsulfinyl, C 1-4 -alkylsulfonyl, sulphamoyl, N—C 1-4 -alkylsulphamoyl, N,N-di-C 1-4 -alkylsulfamoyl, C 1-4 -alkylsulphonamido or C 1-4 -alkylsulphone-N—C 1-4 -alkylamido; a second of the radicals R1, R2, R3 is C 1-6 -alkyl, C 1-6 -alkyl substituted by identical or different substituents selected from halogen, C 3-7 -cycloalkyl, C 1-4 -alkoxy, trifluoromethoxy, hydroxyl, or trifluoromethyl, C 3-7 -cycloalkyl, C 3-7 -cycloalkyl substituted by identical or different substituents selected from halogen, C 1-4 -alkyl, halo-C 1-4 -alkyl, C 3-7 -cycloalkyl, C 1-4 -alkoxy, halo-C 1-4 -alkoxy or hydroxyl, phenyl, phenyl substituted by identical or different substituents selected from halogen, C 1-4 -alkyl, halo-C 1-4 -alkyl, C 1-4 -alkoxy, halo-C 1-4 -alkoxy, C 1-4 -alkylthio, hydroxyl, nitro, C 1-4 -alkylsulfinyl, C 1-4 -alkylsulfonyl, sulphamoyl, N—C 1-4 -alkylsulphamoyl, N,N-di-C 1-4 -alkylsulfamoyl, C 1-4 -alkylsulphonamido or C 1-4 -alkylsulphone-N—C 1-4 -alkylamido; or a mono- or bicyclic aromatic, mono- or bicyclic non-aromatic, heterocyclic radical which contains 1, 2, or 3 heteroatoms independently of one another selected from N, O and S, heterocyclic radical which contains 1, 2, or 3 heteroatoms independently of one another selected from N, O and S substituted by identical or different substituents selected from halogen, C 1-4 -alkyl, halo-C 1-4 -alkyl, C 1-4 -alkoxy, halo-C 1-4 -alkoxy, C 1-4 -alkylthio, hydroxyl, nitro, C 1-4 -alkylsulfinyl, C 1-4 -alkylsulfonyl, sulphamoyl, N—C 1-4 -alkylsulphamoyl, N,N-di-C 1-4 -alkylsulfamoyl, C 1-4 -alkylsuphonamido or C 1-4 -alkylsulphone-N—C 1-4 -alkylamido; a third of the radicals R1, R2, R3 is H, C 1-4 -alkyl, halo-C 1-4 -alkyl, hydroxy-C 1-6 -alkyl, —CHO, —COOH, —COCOOH, —COO—C 1-4 -alkyl, —COO—C 1-4 -Alkphenyl, —COCOO—C 1-4 -alkyl, halogen, cyano, C 1-4 -alkylsulphonyl, suiphamoyl or B—Y; in which B is C 1-8 -alkylene or C 2-8 -alkyenylene; Y is —COOH, —COO—C 1-4 -alkyl, —SO 3 —C 1-4 -alkyl, —CHO or hydroxyl; or the second and third of the radicals R1, R2, R3, together with the C atoms to which they are bonded, form a saturated or unsaturated C 3 -C 7 -cycloalkyl; R4-R11, which can be identical or different, are hydrogen, C 1-6 -alkyl, hydroxy-C 1-6 -alkyl, C 1-4 -alkoxy-C 1-6 -alkyl, hydroxyl, COOH or acyloxy, where vicinal radicals can also represent bonds or geminal radicals, also together with the C atom to which they are bonded, can represent carbonyl or C 3 -C 7 -cycloalkyl; and optical isomers, physiologically tolerable salts and physiologically hydrolysable esters thereof.