Patent ID: 8658602

Claim:
A fusion protein of the formula X-Y-Z, wherein X comprises the Ig-like domain 2 of VEGF-R1 but lacks the Ig-like domains 1 and 3 of a VEGF receptor, with said Ig-like domain 2 of VEGF-R1 being covalently linked to moiety Z via moiety Y; and Y is selected from the group consisting of gly 9 (SEQ ID NO: 27), glu 9 (SEQ ID NO: 28), ser 9 (SEQ ID NO: 29), gly 5 -cys -pro 2 -cys (SEQ ID NO: 30), (gly 4 ser) 3 (SEQ ID NO: 31), Ser-Cys-Val-Pro-Leu-Met-Arg-Cys -Gly-Gly-Cys-Cys-Asn (SEQ ID NO: 32), Pro-Ser-Cys-Val-Pro-Leu-Met-Arg-Cys- Gly-Gly -Cys-Cys-Asn (SEQ ID NO: 13), Gly-Asp-Leu-Ile-Tyr-Arg-Asn-Gln-Lys (SEQ ID NO: 26), and Gly 9 -Pro-Ser-Cys-Val-Pro-Leu-Met-Arg-Cys-Gly-Gly-Cys-Cys-Asn (SEQ ID NO: 34), and Z is a CH3 region of an IgG heavy chain molecule or an Fc portion of an antibody molecule.