Patent ID: 7867734

Claim:
A method for producing an anti-glypican 3 antibody with a modified sugar chain component, the method comprising: (a) providing a cell expressing a nucleic acid encoding an anti-glypican 3 antibody, wherein the cell is a mutant cell that has a reduced capability of adding fucose to sugar chains as compared to a corresponding wild type cell; and (b) culturing the mutant cell, thereby producing the anti-glypican 3 antibody with a modified sugar chain component, wherein the anti-glypican 3 antibody comprises a heavy chain variable region comprising an amino acid sequence selected from the group consisting of SEQ ID NO:81, SEQ ID NO:82, SEQ ID NO:83, SEQ ID NO:84, SEQ ID NO:85, SEQ ID NO:86, and SEQ ID NO:87.