Patent ID: 8916577

Claim:
A compound of formula (I) wherein: R1 is hydrogen, halogen or an optionally substituted group selected from amino, straight or branched C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, cycloalkyl-alkyl, aryl, arylalkyl, heterocyclyl and heterocyclylalkyl; X is a single bond or a divalent radical selected from —NR′—, —CONR′—, —NH—CO—NH—, —O—, —S—, —SO 2 — and —OSO 2 —, wherein R′ is hydrogen or an optionally substituted group selected from straight or branched C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, cycloalkyl-alkyl, aryl, arylalkyl, heterocyclyl and heterocyclylalkyl; one of Y and Z is nitrogen and the other is N—R3, wherein R3 is hydrogen or an optionally substituted group selected from straight or branched C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, cycloalkyl-alkyl, aryl, arylalkyl, heterocyclyl and heterocyclylalkyl or is a group —(CH 2 ) n —, wherein n is 2 or 3, forming a ring with R2, or Y is oxygen and Z is nitrogen, or Y is nitrogen and Z is oxygen; R2 is a group selected from —NR″R′″, —N(OR′″)R″ and OR″, wherein R″ and R′″ are, each independently, hydrogen or an optionally substituted group selected from straight or branched C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, cycloalkyl-alkyl, aryl, arylalkyl, heterocyclyl and heterocyclylalkyl or, together with the nitrogen atom to which they are bonded, R″ and R′″ may form a 5 to 6 membered heteroaryl or heterocyclyl group, optionally containing one additional heteroatom selected among N, O and S; or a pharmaceutically acceptable salt thereof.