Patent ID: 7919488

Claim:
A compound of formula (IIb), wherein: R 2 is 5-9 membered heteroaryl, optionally substituted with one or more R 11 groups; R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are each independently selected from hydrogen, halo, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, —(CR 9 R 10 ) t (C 3 -C 8 cycloalkyl), —(CR 9 R 10 ) t OR 11 , —(CR 9 R 10 ) t N(R 11 R 12 ), —CN, —NO 2 , —CF 3 , —C(O)R 9 , and —C(O) 2 R 9 ; each R 9 and R 10 is independently selected from hydrogen, C 1 -C 8 alkyl, C 3 -C 8 cycloalkyl, C 6 -C 10 aryl, 3-10 membered heterocyclyl, and 5-9 membered heteroaryl; each R 11 and R 12 is independently selected from hydrogen, C 1 -C 8 alkyl, C 3 -C 8 cycloalkyl, C 6 -C 10 aryl, 3-10 membered heterocyclyl, 5-9 membered heteroaryl, —CN, halo, —(CR 16 R 17 ) t OR 18 , and —(CR 16 R 17 ) t C(O)R 18 , wherein each of said C 1 -C 8 alkyl, C 3 -C 8 cycloalkyl, C 6 -C 10 aryl, 3-10 membered heterocyclyl, and 5-9 membered heteroaryl groups is optionally substituted with one more R 15 groups; each R 15 is independently selected from —(CR 9 R 10 ) t R 16 , —(CR 9 R 10 ) t (3-10 membered heterocyclyl), —(CR 9 R 10 ) t (C 3 -C 8 cycloalkyl), —(CR 9 R 10 ) t (5-9 membered heteroaryl), —(CR 9 R 10 ) t (C 6 -C 10 aryl), —(CR 9 R 10 ) t N(R 16 R 17 ), —(CR 9 R 10 )NR 16 C(O)R 17 , —(CR 9 R 10 ) t OR 16 , —(CR 9 R 10 ) t C(O)R 16 , —(CR 9 R 10 ) t C(O) 2 R 16 , —(CR 9 R 10 ) t C(O)N(R 16 R 17 ), —(CR 9 R 10 ) t NR 16 C(O)OR 17 —(CR 9 R 10 ) t NR 16 S(O)N(R 17 R 18 ), —(CR 9 R 10 ) t NR 16 S(O) 2 N(R 17 R 18 ), —(CR 9 R 10 ) t NR 16 S(O)R 17 , —(CR 9 R 10 ) t NR 16 S(O) 2 R 17 , —(CR 9 R 10 ) t NR 16 C(O)N(R 17 R 18 ), —(CR 9 R 10 ) t (halo), —(CR 9 R 10 ) t —OR 16 , and —(CR 9 R 10 ) t S(O) 2 R 16 , wherein each said 3-10 membered heterocyclyl, C 3 -C 8 cycloalkyl, 5-9 membered heteroaryl, and C 6 -C 10 aryl is optionally substituted with one or more R 16 groups; each R 16 , R 17 , and R 18 is independently selected from hydrogen, C 1 -C 8 alkyl, —(CH 2 ) t (C 3 -C 8 cycloalkyl), —(CH 2 ) t (C 6 -C 10 aryl), —(CH 2 ) t (5-9 membered heteroaryl), —(CH 2 ) t (3-10 membered heterocyclyl), halo, —OCH 3 , and —OH; R 19 and R 20 are independently selected from hydrogen and C 1 -C 8 alkyl; and each t is independently selected from 0, 1, 2, 3, and 4; or a pharmaceutically acceptable salt thereof.