Patent ID: 7253188

Claim:
A compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, wherein R 1 is —S(O)p-A, —S—(O)q-B or —O-D, wherein p and q, which are the same or different, each represent an integer from 0 to 2, A is a straight chain C1-C10 alkyl group which may be substituted by R 10 , and B and D each independently represent R 12 which may be substituted by R 10 ; R 2 is a hydrogen atom, a halogen atom, or a straight chain or branched C1-C6 alkyl group which may be substituted by R 10 ; one of X 1 or X 2 is N and the other is CH; the formula (II): shows a monocyclic or bicyclic heteroaryl group which has a nitrogen atom adjacent to the carbon atom bonded to the amide group, and the heteroaryl group may be substituted by R 10 ; R 10 is R 11 , or a hydrocarbon group which may be substituted by R 11 ; R 11 is a hydrogen atom, amino, carbamoyl, carbamoylamino, carbamoyloxy, carboxyl, cyano, sulfamoyl, trifluoromethyl, a halogen atom, hydroxyl, formyl, straight chain C1-C6 alkyl, C3-C6 cyclic hydrocarbon, aralkyl, N-aralkylamino, N,N-diaralkylamino, aralkyloxy, aralkylcarbonyl, N-aralkylcarbamoyl, aryl, arylthio, N-arylamino, aryloxy, arylsulfonyl, arylsulfonyloxy, N-arylsulfonylamino, arylsulfamoyl, N-arylcarbamoyl, aroyl, aroxy, C2-C6 alkanoyl, N-C2-C6 alkanoylamino, C1-C6 alkylthio, N-C1-C6 alkylsulfamoyl, N,N-di-C1-C6 alkylsulfamoyl, C1-C6 alkylsulfinyl, C1-C6 alkylsulfonyl, N-C1-C6 alkylsulfonylamino, C1-C6 alkoxy, C1-C6 alkoxycarbonyl or C1-C6 alkylamino; and R 12 is phenyl, naphthyl, isoxazolyl, isothiazolyl, imidazolyl, oxazolyl, thiazolyl, thiadiazolyl, thienyl, triazolyl, tetrazolyl, pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl, pyrazolyl, pyrrolyl, pyranyl, furyl, furazanyl, imidazolidinyl, tetrahydrofuranyl, piperazinyl, piperidinyl, pyrrolidinyl, morpholino, isoquinolyl, isoindolyl, indolyl, ethylene dioxyphenyl, methylene dioxyphenyl, quinolyl, pyridothiazolyl, dihydroindolyl, tetrahydroquinolinyl, tetrahydroisoquinolinyl, benzimidazolyl, benzoxazolyl, benzothiazolyl, benzotriazolyl or benzofuranyl.