Patent ID: 7244766

Claim:
A compound of the formula (1): or a pharmaceutically acceptable salt, isomer, tautomer thereof, wherein: the (CH 2 ) n —C(═O)Q 1 group is in the meta or para position; R 1 and R 2 are independently selected from H and C 1 –C 4 alkyl; n is 0, 1 or 2; and Q 1 is selected from: and *—NR 8 —Q 2 —A; p is 1 or 2; Q 2 is C 1 –C 4 alkylenyl optionally substituted with one hydroxy group; R 8 is H or C 1 –C 4 alkyl; A is pyridyl optionally substituted with OH, C 3 –C 7 cycloalkyl optionally substituted with OH, or R 3 , R 4 , R 5 , R 6 and R 7 are independently H, C 1 –C 4 alkyl, OR 9 , SR 9 , halo, CN, CF 3 , OCF 3 , COOR 9 , SO 2 NR 9 R 10 , CONR 9 R 10 , NR 9 R 10 , NHCOR 10 or phenyl optionally substituted with 1 to 3 OR 9 , halo or C 1 –C 4 alkyl; R 9 and R 10 are independently H or C 1 –C 4 alkyl; and the * represents the attachment point to the carbonyl group of formula (1); provided that the group Q 1 is substituted with at least one hydroxy group.