Patent ID: 8639484

Claim:
A process for multi-nozzle biopolymer deposition of heterogeneous materials to create or modify a composite biopolymer multi-part three-dimensional assembly having at least one biomimetic and at least one non-biomimetic feature comprising: (a) importing data from MRI, CT or other patient specific data into a CAD environment; (b) utilizing the CAD environment and said data to design and/or modify the composite multi-part assembly, using at least two of Boolean, scaling, smoothing, and mirroring CAD operations; (c) converting the CAD design into a three-dimensional heterogeneous material and multi-part assembly model in a format suitable for three-dimensional, multi-nozzle printing, wherein the design comprises at least one biomimetic feature and at least one non-biomimetic feature; and (d) printing the composite assembly by simultaneously depositing the heterogeneous materials using multiple, different, specialized nozzles, wherein the simultaneous depositing includes direct deposition of cells.