Patent ID: 8716343

Claim:
A method for inhibiting bacterial infection and/or endotoxemia, the method comprising contacting bacterial cells with a calixarene-based peptide mimetic in an amount effective to kill the bacteria, and/or to neutralize endotoxin, wherein the calixarene-based peptide mimetic comprises Compound 46 having the formula Compound 36 having the formula Compound 41 having the formula Compound 4 having the formula Compound 17 having the formula Compound 3 having the formula Compound 11a having the formula Compound 39 having the formula Compound 12 having the formula Compound 21 having the formula and Compound 42 having the formula wherein R═(CH 2 ) 4 NHC(═NH)NH 2 ; or an isomer, tautomer, salt, solvate, or polymorph.