Patent ID: 7361473

Claim:
A method of diagnosing an acute coronary syndrome in a subject, said method comprising performing a first immunoassay that detects a first marker selected from the group consisting of BNP and NT-proBNP on a test sample obtained from said subject; performing a second immunoassay that detects a second marker selected from the group consisting of free cardiac troponin I, complexed cardiac troponin I, free and complexed cardiac troponin I, free cardiac troponin T, complexed cardiac troponin T, free and complexed cardiac troponin T on a test sample obtained from said subject; and correlating the results obtained from said first and second immunoassays to the presence or absence of an acute coronary syndrome in said subject by comparing a result from said first immunoassay to a first threshold level and comparing a result from said second immunoassay to a second threshold level, wherein when said first immunoassay result exceeds said first threshold level and said second immunoassay result does not exceed said second threshold level, the presence of myocardial ischemia in the absence of myocardial infarction is diagnosed in said subject, and when said second immunoassay result exceeds said second threshold level myocardial infarction is diagnosed in said subject.