Patent ID: 8012200

Claim:
A method for endovascular magnetic targeting drug delivery in a vascular wall and adjoining tissues, comprising: implanting an endovascular mesh stent with paramagnetic properties in an area of interest by using a first catheter; injecting a polymeric magneto-responsive carrying agent in a form of particles, containing a drug; introducing at least one temporary catheter into a right atrium, and/or in ventricles of heart, and/or in a coronary sinus, and/or in a coronary vein, such that a distal end of the temporary catheter is positioned in proximity to the implanted endovascular mesh stent; generating a magnetic field at the area of interest using the temporary catheter; adjusting the magnetic field by means of a permanent magnet and/or a solenoid with the core, connected to an electric power source, wherein the permanent magnet and/or the solenoid is at the distal end of the at least one temporary catheter, and wherein a maximum magnetic field is at the implanted endovascular mesh stent; and removing the magnetic field to return the implanted endovascular mesh stent to a non-magnetized state, wherein a size of particles of the polymeric magneto-responsive carrying agent is between 0.01-1.0 microns, and wherein the magnetic field has a strength of no more than 1 Tesla.