Patent ID: 7531692

Claim:
A compound of formula (I): wherein: B is H or the side chain of an alpha-amino acid; R and R 1 are the same and are linear or branched C 1 -C 4 alkyl; or together with the carbon atom to which they are linked form a ring containing 3 to 6 carbon atoms; R 2 is H, CF 3 , OCF 3 or a halogen selected from the group consisting of F, Cl, Br, and I; and Ar is phenyl substituted with one or more groups R 3 , wherein R 3 represents: halogen selected from the group consisting of F, Cl, Br, and I; CF 3 ; C 3 -C 8 cycloalkyl optionally substituted with one or more C 1 -C 4 alkyl and/or oxo groups; CH═CH 2 ; NO 2 ; CH 2 OH; CN; methylenedioxy; ethylenedioxy; phenyl optionally substituted with one or more of the following groups: halogen selected from the group consisting of F, Cl, Br, and I; CF 3 ; OCF 3 ; OH; linear or branched C 1 -C 4 alkyl; a saturated heterocycle with at least 4 carbon atoms and at least 1 heteroatom; and C 3 -C 8 cycloalkyl optionally substituted with one or more linear or branched C 1 -C 4 alkyl groups, CF 3 and/or OH; OR 4 or NHCOR 4 wherein R 4 is CF 3 , linear or branched C 2 -C 6 alkenyl or alkynyl; benzyl; phenyl optionally substituted with one or more of the following groups: halogen as previously defined, CF 3 , OCF 3 , OH, linear or branched C 1 -C 4 alkyl; a saturated heterocycle with at least 4 carbon atoms and at least 1 heteroatom; C 3 -C 8 cycloalkyl optionally substituted with one or more linear or branched C 1 -C 4 alkyl groups, CF 3 and/or OH; and SR 5 , SO 2 R 5 or COR 5 wherein R 5 is linear or branched C 1 -C 6 alkyl; or Ar is a heterocycle selected from the group consisting of pyrrole, pyrazole, furan, thiophene, indole, isoindole, benzofuran, benzothiophene, imidazole, oxazole, isoxazole, thiazole, benzoimidazole, benzoxazole, benzothiazole, pyrimidine, pyrazine, quinoline, isoquinoline, quinazoline, quinoxaline, dibenzofuran, dibenzothiophene, thianthrene, carbazole, pyridazine, cinnoline, phthalazine, 1,5-naphthiridine, 1,3-dioxole, and 1,3-benzodioxole, said heterocycle being optionally substituted with one or more groups R 3 as defined above; or a pharmaceutically acceptable salt or ester thereof.