Patent ID: 8133489

Claim:
A method of treating cancer in a mammal, comprising administering to said mammal in need thereof an effective amount of the antibody or fragment comprising a heavy chain variable region having the sequence (SEQ ID NO: 6) EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYLMTWVRQAPGKGLEWV ANIKQDGSEKYYVDSVKGRFTISRDNAKNSLNLQMNSLRAEDTAVYYC TRDGYSSGRHYGMDVWGQGTTVIVSS and a light chain variable region having the sequence (SEQ ID NO: 8) EIVLTQSPATLSLSPGERATLSCRASQSVSRYLAWYQQKPGQAPRLL IYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNW PRTFGQGTKVEIK, wherein the cancer is selected from the group consisting of tumor cells originating in the colon, pancreas, lung, and breast.