Patent ID: 7012062

Claim:
A regime or regimen for inducing increased levels of free TNF-α (Tumor Necrosis Factor-alpha) in plasma, comprising orally administering to a mammalian organism in need of such treatment, a thus effective amount of a pegilated lysozyme c having the formula: [CH 3 O—(CH 2 —CH 2 —O) n —CH 2 —CH 2 ] x —(NH) y Lysozyme c. (Z)m wherein: (NH) y Lysozyme c is chicken egg-white lysozyme c; y is the number of free amino groups of lysine molecules present in the molecule of chicken egg-white lysozyme c, and varies from 5 to 30; x is between 1 and y; n is between 5 and 1000; Z is a pharmaceutically acceptable acid; and m is between 1 and y.