Patent ID: 8778614

Claim:
A method for isolating a compound which has gained at least one functional group, the method comprising (a) providing: (i) a compound which can gain a functional group, the compound being directly covalently bound to at least one labeled non-radioactive signaling moiety; (ii) a chemical, enzymatic or catalytic source of the functional group which can be gained by the compound; and (iii) means to separate the compound which has gained the functional group from the compound which has not gained the functional group; (b) forming a mixture comprising the labeled compound and the source of the functional group, and incubating the mixture under conditions suitable for the compound to gain the functional group; (c) separating and thereby isolating any compound which has gained the functional group from any compound which has not gained the functional group by precipitating said compound which has gained the functional group from the mixture; and (d) resolubilizing said compound which has gained the functional group.