Patent ID: 7833793

Claim:
A method of monitoring inhibition of platelet function for an individual mammal comprising: determining a standard value for a particular mammal by: collecting platelet-containing standard blood in an amount of less than 100 μl from the particular mammal, mixing the standard blood with a platelet agonist to generate agonist-activated standard blood, and monitoring an extracellular platelet-release-reaction product in the agonist-activated standard blood to generate the standard value for the particular mammal; wherein the standard blood is not treated with a cyclooxygenase inhibitor, and wherein the extracellular platelet-release-reaction product is ATP; treating the particular mammal with the cyclooxygenase inhibitor after the collecting of the standard blood; collecting platelet-containing mammalian blood from the particular mammal after the particular mammal has been treated with the cyclooxygenase inhibitor, wherein less than 100 μl of treated blood is collected from the particular mammal; mixing the collected treated blood with the platelet agonist to generate agonist-activated treated blood; monitoring the extracellular platelet-release-reaction product in the agonist-activated treated blood to generate a measurement value; and comparing the measurement value to the standard value for the particular mammal.