Patent ID: 7514435

Claim:
A compound of formula II wherein W is —CR 9 — or —N—; R 1 is H, C 1 -C 6 alkyl, arylalkyl, C 3 -C 8 cycloalkyl, C 9 -C 14 bicycloalkyl, C 6 -C 10 aryl, C 5 -C 13 heteroaryl, C 4 -C 12 heterocyclyl and 3 to 8- membered heterocycloalkyl and each of said groups optionally substituted with 1 to 3 groups selected from the group consisting of halogen, —OH, —OR 7 , —C(═O)OR 7 —, —S(═O)NHR 7 , —SO 2 NHR 7 , —SO 2 R 7 , alkyl, substituted alkyl, —CN, —NHR 7 , —CONHR 7 , —OCONHR 7 , —CONHSO 2 R 7 , —NHCONHR 7 , —CH 2 OR 7 , —CH 2 CH 2 OH, alkoxy, substituted alkoxy, aryl or substituted aryl, R 7 is hydrogen or C 1 -C 4 alkyl; C 3 -C 6 cycloalkyl, aryl, arylalkyl, heteroaryl, heterocyclyl, aryloxy, substituted aryloxy, —CF 3 and —OCF 3 , two of which may be attached to the same ring carbon atom; R 2 is hydrogen, halogen, —NR 8 R 9 , C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 1 -C 6 alkynyl, C 3 -C 8 cycloalkyl, arylalkyl or C 4 -C 8 heterocyclyl with at least one atom on the ring selected from nitrogen or oxygen atom, and each of said R 2 groups optionally substituted with 1 to 3 groups selected from the group consisting of —OH, OR 8 , —NH 2 , —NR 8 R 9 , —CONHR 8 , —OCONHR 8 , —CONHSO 2 R 8 , —NHCONHR 8 , —SR 8 , —S(═O)R 8 , —SO 2 R 8 , —SO 2 N R 8 R 9 ; R 8 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, an optionally substituted aryl or heteroaryl group; said substituents on the substituted aryl or substituted heteroaryl group are selected from the group consisting of one or more hydrogen, halogen, alkyl, substituted alkyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, aryl, substituted aryl, arylalkyl, substituted arylalkyl, aryloxy and substituted aryloxy; R 9 is hydrogen, halogen, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl or C 1 -C 6 alkoxy; or R 8 and R 9 can be taken together with the nitrogen atom to which they are attached to form an optionally substituted heterocyclyl ring; or a pharmaceutically acceptable salt or stereoisomer thereof.