Patent ID: 7507413

Claim:
An albumin fusion protein comprising a fractalkine polypeptide fused to an albumin polypeptide, wherein said fractalkine polypeptide is selected from: (a) a full-length fractalkine; (b) a mature fractalkine; and (c) a fragment of fractalkine, wherein said fragment has chemotactic activity; and wherein said albumin polypeptide is selected from: (i) a full-length albumin; (ii) a mature albumin; (iii) a fragment of albumin, wherein said fragment of albumin has the ability to prolong the serum half-life of the fused fractalkine polypeptide compared to the unfused fractalkine polypeptide; (iv) a polypeptide consisting of an amino acid sequence at least 95% identical to albumin (SEQ ID NO:18), wherein said polypeptide has the ability to prolong the serum half-life of the fused fractalkine polypeptide compared to the unfused fractalkine polypeptide; (v) amino acids 1 to 585 of SEQ ID NO:18; and (vi) amino acids 1 to 387 of SEQ ID NO:18.