Patent ID: 6849663

Claim:
A method of treating an inflammatory and/or autoimmune pathology induced by inflammatory cytokines, which method comprises administering to a patent in need of same an effective amount of 2-aminotetraline of the formula (I) or a pharmacologically acceptable salt of the formula (II) wherein: R and R 1 are independently halogen, hydroxy, or C 1 -C 4 alkoxy optionally substituted in position ω with a group selected from OH, NH 2 or NR 3 R 4 , wherein R 3 and R 4 are independently H, C 1 -C 4 alkyl, unsubstituted or substituted in position ω with groups OH, NH 2 , C 1 -C 4 alkanoyl, C 1 -C 4 alkyl, carbamoyl, carbamoyloxy, amino, or amino-substituted NR 3 R 4 , where R 3 and R 4 have the above meanings, R 2 is hydrogen, halogen, hydroxy or methoxy, with the proviso that the 2-aminotetraline excludes (a) R═R 1 ═CH 3 O or OH, R 2 ═H, (b) R═F, R 1 ═CH 3 O or OH, R 2 ═H, (c) R 1 ═OCH 3 , R═CH 3 and R 2 ═H, or (d) R═R 1 ═R 2 ═CH 3 O, and X − is the monovalent anion of a pharmacologically acceptable acid.