Patent ID: 8361022

Claim:
A device for transdermally delivering a PTH-based agent to a patient, comprising: a microprojection member having a plurality of microprojections that are adapted for pulsatile delivery of a PTH based agent and to pierce the stratum corneum of the patient; and a biocompatible coating disposed on said microprojection member, said coating being formed from a coating formulation comprising at least one PTH-based agent, wherein said PTH based agent is hPTH(1-34) or salts thereof and is at a dose of 10-1000 μg that results in a plasma C max of at least 50 pg/ml after a single application, wherein said coating formulation includes a biocompatible carrier selected from the group consisting of bioengineered human albumin, polyglutamic acid, polyaspartic acid, polyhistidine, pentosan polysulfate, polyamino acids, sucrose, trehalose, melezitose, raffinose, stachyose and mannitol, and wherein said biocompatible carrier is in the range of 2-70 wt. % of said coating formulation.