Patent ID: 7744564

Claim:
A system for delivering one or more agents to tissue surrounding a target vessel of a patient's body, the system comprising: an elongate delivery device comprising: a proximal tubular portion extending from a proximal end thereof to a distal end thereof, over a length sufficient to reach a coronary sinus of the patient from a subclavian entry location; a distal portion sized for introduction into the target vessel, the distal portion including an expandable sheath, a stiffening member and a balloon, the expandable sheath including a proximal end, the proximal end of the sheath surrounding and overlying the distal end of the proximal tubular portion, being attached thereto, the expandable sheath extending from the proximal end thereof to a distal end thereof, the stiffening member including a proximal end, also being attached to the distal end of the proximal tubular portion, the stiffening member extending from the proximal end thereof to a distal end thereof and being attached to the expandable sheath, the distal end of the stiffening member being located distal to the distal end of the expandable sheath, and the balloon being attached to the stiffening member and spaced apart from the distal end of the expandable sheath; a first lumen extending within the proximal tubular portion, from the proximal end of the tubular portion to the distal end of the tubular portion, and further extending distally, within the expandable sheath to a distal opening thereof, which distal opening terminates the distal end of the expandable sheath; and a second lumen extending within the proximal tubular portion, from the proximal end of the tubular portion to the distal end of the tubular portion, and further extending distally within the stiffening member, the second lumen in fluid communication with the balloon; and a source of the one or more agents coupled to the proximal end of the proximal tubular portion and communicating with the first lumen in order to deliver the one or more agents through the first lumen and out the distal end thereof at a sufficient pressure to cause the one or more agents to extravasate through a wall of the target vessel, that is located downstream of the distal opening, and into surrounding tissue, when the distal portion of the device is introduced into the target vessel.