Patent ID: 7708999

Claim:
A method of treating arthritis, comprising administering to a patient, as an active ingredient, an antibody which specifically binds to FGF-8 to inhibit activity of FGF-8, wherein the antibody is a monoclonal antibody selected from an antibody produced by a hybridoma, a humanized antibody and an antigen-binding fragment thereof, wherein the humanized antibody is a human chimeric antibody or a human complementarity determining region (CDR)-grafted antibody comprising CDRs of VH and VL of a monoclonal antibody which specifically binds to FGF-8 to inhibit activity of FGF-8 and CH and CL of a human antibody, wherein CDR1, CDR2 and CDR3 of VH comprise the amino acid sequences of SEQ ID NOS: 7, 8 and 9 respectively and CDR1, CDR2 and CDR3 of VL comprise the amino acid sequences of SEQ ID NOS: 10, 11 and 12 respectively.