Patent ID: 7208487

Claim:
A compound selected from those represented by the formula I: wherein: R 1 , R 2 , R 3 and R 4 are each independently chosen from hydrogen, optionally substituted alkyl, optionally substituted alkoxy, halogen, hydroxyl, nitro, cyano, dialkylamino, alkylsulfonyl, alkylsulfonamido, alkylthio, carboxyalkyl, carboxamido, aminocarbonyl, optionally substituted aryl and optionally substituted heteroaryl; R 5 and R 5′ are each independently chosen from hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; or R 5 and R 5′ taken together form an optionally substituted 3- to 7-membered carbocyclic ring; R 6 is hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, or optionally substituted heteroaralkyl; R 7 , R 7′ , R 8 , R 8′ , R 9 and R 9′ are each independently chosen from hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; one of X and Y is C(R 10 )(R 11 ), and the other of X and Y is N(R 12 ), wherein R 10 and R 11 are each independently chosen from H, optionally substituted alkyl, optionally substituted aryl and optionally substituted heteroaryl; and R 12 is H, optionally substituted alkyl, optionally substituted aralkyl, optionally substituted heteroaralkyl, optionally substituted alkylcarbonyl, optionally substituted arylcarbonyl, optionally substituted heteroarylcarbonyl, optionally substituted aralkylcarbonyl, optionally substituted heteroaralkylcarbonyl, optionally substituted alkoxycarbonyl, optionally substituted aryloxycarbonyl, optionally substituted heteroaryloxycarbonyl, optionally substituted aralkyloxycarbonyl, or optionally substituted heteroaralkyloxycarbonyl; wherein the term “heteroaryl” means a 5 or 6 membered heteroaromatic ring containing 1–4 heteroatoms selected from O, N and S; a bicyclic 9 or 10 membered heteroaromatic ring system containing 1–4 heteroatoms selected from O, N and S; or a tricyclic 12–14 membered heteroaromatic ring system containing 1–4 heteroatoms selected from O, N and S; including single stereoisomers and mixtures of stereoisomers thereof, and pharmaceutically acceptable salts thereof.