Patent ID: 7709523

Claim:
A method of treating migraine, comprising: administering to a mammal having a migraine a therapeutically effective amount of an α-aminoamide of formula (I): wherein: A is a or —(CH 2 ) m — or —(CH 2 ) n —X—, wherein m is 1 or 2; n is zero, 1 or 2; and X is —O—, —S— or —NH—; R is a phenyl ring, unsubstituted or substituted by one or two substituents independently selected from halogen, hydroxy, C 1 -C 4 alkyl, C 1 -C 3 alkoxy and trifluoromethyl; R 1 is hydrogen or C 1 -C 3 alkyl; R 2 is hydrogen or C 1 -C 2 alkyl, unsubstituted or substituted by hydroxy or phenyl; phenyl, unsubstituted or substituted by one or two substituents independently selected from C 1 -C 3 alkyl, halogen, hydroxy, C 1 -C 2 alkoxy or trifluoromethyl; R 3 is hydrogen or C 1 -C 3 alkyl; or an optically active isomer, racemic mixture, or pharmaceutically acceptable derivative thereof.