Patent ID: 7396920

Claim:
An isolated nucleic acid comprising: (i) a nucleotide sequence as shown in SEQ ID NO:1 encoding carboxy terminal modulating protein, said protein having a protein kinase B binding activity, protein kinase B inhibiting activity, or tumor suppressive activity; (ii) a nucleotide sequence encoding carboxy-terminal modulating protein, said protein having a protein kinase B binding activity, protein kinase B inhibiting activity, or tumor suppressive activity, said nucleotide sequence differing from SEQ ID NO:1 by codon usage; (iii) a nucleotide sequence encoding a carboxy-terminal modulating protein homologue with at least 95% identity to SEQ ID NO:2, said protein homologue having a protein kinase B binding activity, protein kinase B inhibiting activity, or tumor suppressive activity, said nucleotide sequence differing from SEQ ID NO:1 by having at least one inserted, deleted or altered codon; or (iv) a nucleotide sequence fully complementary to the nucleotide sequences of (i), (ii) or (iii).