Patent ID: 7736672

Claim:
A process for making drug-containing multiparticulates comprising the steps: (a) forming multiparticulates comprising a drug, a pharmaceutically acceptable carrier, and an poloxamer, said carrier having a melting point of T m ° C.; and (b) treating said multiparticulates of step (a) by at least one of (i) heating said multiparticulates to a temperature of at least 35° C. and less than (T m ° C. minus 10° C.), and (ii) exposing said multiparticulates to a mobility enhancing agent, to form a post-treated multiparticulate; wherein step (b) is conducted for a period of time sufficient to achieve a degree of crystallinity of said drug in said multiparticulates that is greater than the crystallinity of said drug in a control composition consisting essentially of the untreated multiparticulates of step (a) and wherein said carrier is a mixture of glyceryl mono-, di-, and tribehenates.