Patent ID: 8557798

Claim:
A compound having the structural formula or a pharmaceutically acceptable salt or solvate thereof, wherein q is 1, 2, or 3; R 2 , R 3 , R 4 , R 15 and R 16 are each independently selected from the group consisting of H, alkyl, and —CF 3 ; R 24 is present or absent and, when present, is 1 to 5 groups independently selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heterocycloalkylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, arylcycloalkyl, halo, —CF 3 —SH, —OR 19 , —CN, —C(O)R 20 , —C(O)R 19 , —S(O) 0-2 R 21 , —S(O) 1-2 N(R 22 )(R 23 ), —C(O)N(R 22 )(R 23 ), —N(R 22 )C(O)R 20 , —N(R 22 )C(O)N(R 22 )(R 23 ), —N(R 22 )C(O)OR 19 , —N(R 22 )S(O) 1-2 R 21 , —NO 2 , —N═C(R 22 )(R 23 ) and —N(R 22 )(R 23 ); each R 19 (when present) is selected from the group consisting of H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkylalkyl, heteroaryl, arylalkyl, heteroarylalkyl, heterocycloalkyl and heterocycloalkylalkyl; each R 20 (when present) is selected from the group consisting of H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkylalkyl, heteroaryl, arylalkyl, heteroarylalkyl, heterocycloalkyl, heterocycloalkylalkyl and amino); each R 21 (when present) is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkylalkyl, heteroaryl, arylalkyl, heteroarylalkyl, heterocycloalkyl and heterocycloalkylalkyl; and each R 22 and each R 23 (when present) is independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkylalkyl, heteroaryl, arylalkyl, heteroarylalkyl, heterocycloalkyl and heterocycloalkylalkyl.