Patent ID: 7196107

Claim:
A compound of formula (I) or pharmaceutically acceptable salts and solvates thereof wherein R 1 and R 2 are independently H or C1–3alkyl; m is 0–3; X 1 is NH, NCH 3 , O, or S; R 3 , R 4 and R 5 are independently H, CH 3, CF 3, OCH 3, allyl or halogen; X 2 is (CR 10 R 11 )n wherein n is 1 or 2; R 10 and R 11 independently represent H, fluorine or C 1-6 alkyl; R 26 and R 27 are independently H, C 1-3 alkyl or R 26 and R 27 together with the carbon atom to which they are bonded form a 3–5 membered cycloalkyl ring; R 6 and R 7 independently represent H, fluorine or C 1-6 alkyl; R 9 is C 1-6 alkyl or CF 3 ; one of Y and Z is N, the other is S or O; each R 8 independently represents CF 3, OCH 3, CH 3 or halogen; y is 0, 1, 2, 3, 4, 5.