Patent ID: 7176279

Claim:
A method for stimulating sexual response in a mammal, comprising administering a pharmaceutically sufficient amount of a composition comprising a cyclic peptide selected from the group consisting of: Ac-Nle-cyclo(-Asp-D-His-D-Phe-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-Phe-Arg-Trp-Lys)-OH (SEQ ID NO:2), Ac-Nle-cyclo(-Asp-Phe-D-Phe-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe-Lys-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-Trp-D-Phe-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe-D-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-D-Trp-Lys)-OH, Ahx-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-Tyr-D-Phe-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe(4-Cl)-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe-Orn-Trp-Lys)-OH, Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Nal 1-Lys)-OH, Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Bip-Lys)-OH, and Cyclo(-Succ-His-D-Phe-Arg-Trp-Lys)-OH, or a pharmaceutically acceptable salt thereof, for a time and under conditions effective to stimulate a sexual response.