Patent ID: 7205291

Claim:
A carbapenem compound represented by the formula [1]: wherein ring E is benzene or thiophene; R 1 is C 1 to C 3 alkyl or C 1 to C 3 alkyl substituted by hydroxy; A is —CH 2 —O— and R 0 is the formula [2]: wherein X is oxygen atom, R 2 is (1) hydrogen atom, (2) C 1 to C 6 alkyl, (3) C 3 to C 7 cycloalkyl, (4) aryl which may optionally contain heteroatom(s) therein, (5) aralkyl in which ring may optionally contain heteroatom(s), or (6) 3 to 7 membered hetero ring, R 3 is (2) C 1 to C 6 alkyl, (3) C 3 to C 7 cycloalkyl, (4) aryl which may optionally contain heteroatom(s) therein, (5) aralkyl in which ring may optionally contain heteroatom(s), or (6) 3 to 7 membered hetero ring; or R 2 and R 3 are combined together with the N atom to form a 3 to 7 membered hetero ring, or A is —CH 2 —NH— and R 0 is the formula [3]: wherein X is oxygen atom, m is 1, R 3a is C 1 to C 6 alkyl, C 3 to C 7 cycloalkyl, aryl which may optionally contain heteroatom(s) therein, aralkyl in which ring may optionally contain heteroatom(s), or 3 to 7 membered hetero ring; R is hydrogen atom, C 1 to C 6 alkyl, C 2 to C 12 alkyloxyalkyl, (2-oxo-1,3-dioxol-4-yl)methyl, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl, (5-tert-butyl-2-oxo-1,3-dioxol-4-yl)methyl, (5-phenyl-2-oxo-1,3-dioxol-4-yl)rnethyl, or the formula [4]: wherein R 6 is hydrogen atom or C 1 to C 6 alkyl, R 7 is C 1 to C 6 alkyl, or C 3 to C 7 cycloalkyl and n is 0 or 1, and Y is hydrogen atom, or its pharmaceutically acceptable salt.