Patent ID: 8470828

Claim:
A compound of formula (I) wherein X is O or S; Y is —C(O)—or —S(O) 2 —; A is a single bond or double bond, with the proviso that when X is S then A is a double bond; R 1 is hydrogen, C 1-7 alkyl, C 1-7 haloalkyl, C 2-7 alkenyl, C 2-7 alkynyl, cycloalkyl, heterocycloalkyl, aryl, aryl anellated to heterocycloalkyl, heteroaryl, or —N(R 6 ) 2 ; wherein C 1-7 alkyl, C 1-7 haloalkyl, C 2-7 alkenyl, and C 2-7 alkynyl are optionally substituted by one to three independent R 4 ; and wherein cycloalkyl, heterocycloalkyl, aryl, aryl anellated to heterocycloalkyl, and heteroaryl are optionally substituted by one to three independent R 5 ; R 2 and R 3 are each independently hydrogen, halogen, C 1-7 alkyl, C 1-7 haloalkyl, hydroxy, C 1-7 alkoxy or C 1-7 haloalkoxy; R 4 is cyano, cycloalkyl, heterocycloalkyl, aryl, aryl anellated to heterocycloalkyl, heteroaryl, —C(O)N(R 6 ) 2 , —N(R 6 ) 2 , —NH(CO)—C 1-7 alkyl, hydroxy, C 1-7 alkoxy, C 1-7 haloalkoxy, oxo, or —S(O) 2 R 7 , wherein cycloalkyl, heterocycloalkyl, aryl, aryl anellated to heterocycloalkyl, and heteroaryl are optionally substituted by one to three independent R 5 ; R 5 is halogen, cyano, C 1-7 alkyl, C 1-7 haloalkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, —C(O)N(R 6 ) 2 , —N(R 6 ) 2 , —NH(CO)—C 1-7 alkyl, hydroxy, C 1-7 alkoxy, C 1-7 haloalkoxy, oxo, or —S(O) 2 R 7 , wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are optionally substituted by one to three substituents independently selected from the group consisting of halo, cyano, C 1-7 alkyl, C 1-7 haloalkyl, hydroxy, alkoxy, and oxo; R 6 is hydrogen, or C 1-7 alkyl; and R 7 is hydrogen, C 1-7 alkyl, or aryl, wherein aryl is optionally substituted by one to three substituents independently selected from the group consisting of halogen, cyano, C 1-7 alkyl, C 1-7 haloalkyl, hydroxy, C 1-7 alkoxy, C 1-7 haloalkoxy; or a pharmaceutically acceptable salt or ester thereof.