Patent ID: 8546574

Claim:
Method for the preparation of an enantiomerically pure Tenatoprazole sodium salt, said method comprising the steps of: obtaining a tenatoprazole potassium salts, represented by the following general formula: comprising an equimolar mixture of enantiomers of R and S configuration; and crystallizing said tenatoprazole potassium salts in the form of conglomerates, said salts being selected from the group consisting of tenatoprazole potassium salt dihydrate, potassium tenatoprazole dimethanolate, potassium tenatoprazole diethanolate and potassium tenatoprazole ethylene glycolate; conducting the resolution of the optical enantiomers of one of the corresponding racemic potassium salts, wherein said resolution is according to a process of preferential crystallization, followed by conversion of one of said optical enantiomers of the potassium salt into the corresponding enantiomer of the sodium salt.