Patent ID: 8080397

Claim:
A method for production of quinic acid comprising: (A) providing one or more enzymes selected from: (i) a 3-deoxy-D-arabino-heptulosonic acid-7-phosphate (DAHP) synthase enzyme that is insensitive to feedback inhibition by aromatic amino acids, (ii) a 3-dehydroquinate (DHQ) synthase enzyme, and (iii) a shikimate dehydrogenase enzyme; wherein at least one of said enzymes is a recombinant enzyme, wherein the DAHP synthase, DHQ synthase, and shikimate dehydrogenase are encoded by E. coli aroF FBR , E. coli aroB, and E. coli aroE genes, respectively; and (B) allowing the one or more enzymes to catalyze one or more reactions to synthesize quinic acid from erythrose-4-phosphate (E4P) and phosphoenolpyruvate (PEP); thereby producing quinic acid.