Patent ID: 8822692

Claim:
A compound having the general formula I wherein: R 1 is —CH═NOR 4 with the meaning of iminoxy, —CH 2 NHOR 4 , —CH 2 XR 5 , —CH═CHR 6 , —CH═NR 7 , or NH 2 —(C 3 -C 6 )alkyl-; R 7 is guanidino; R 6 is NH 2 —(C 1 -C 6 )alkyl-; R 5 is NH 2 —(C 1 -C 6 )alkyl-; R 4 is NH 2 —(C 1 -C 6 )alkyl-, piperidinyl, hydroxy-(C 1 -C 6 )-alkyl-, hydroxy-(C 1 -C 6 )-alkyloxy-(C 1 -C 6 )-alkyl-, or carboxy-(C 1 -C 6 )-alkyl-; X is O or S; the endocyclic symbol represents a single or a double bond and when it represents a double bond the symbol linking R 3 to the carbocycle represents a single bond and the carbocycle ring A is partially unsaturated possessing only one double bond between carbon atoms 13-14; the symbol linking R 2 to the carbocycle represents a single or a double bond; R 2 is H or hydroxyl when the symbol linking R 2 to the carbocycle represents a single bond; or R 2 is O or N˜OR 8 when the symbol linking R 2 to the carbocycle represents a double bond with the meaning of carbonyl or oxime respectively; R 8 is H or (C 1 -C 6 )alkyl; the symbol linking R 3 to the carbocycle represents a single or a double bond; R 3 is H when the symbol linking R 3 to the carbocycle represents a single bond; or R 3 is O or N˜OR 8 when the symbol linking R 3 to the carbocycle represents a double bond with the meaning of carbonyl or oxime respectively; carbocycle ring A is aromatic or partially unsaturated possessing only one double bond between carbon atoms 13-14; their optically active forms such as enantiomers, diastereomers, their racemate forms, and pharmaceutically acceptable salts thereof.