Patent ID: 6900008

Claim:
A combination comprising: a formulation solution including a spasticity minimizing agent, an anti-coagulating agent and at least one vasodilatory agent, and a blood vessel graft suitable for use in coronary artery bypass grafting in contact with the solution wherein the formulation is effective to reduce vasoconstriction in the graft induced by inotropic agents for up to 48 hours, wherein the spasticity minimizing agent is selected from the group consisting of haloalkylamine alpha adrenergic blocking agents and wherein the at least one vasodilatory agent is selected from the group consisting of lidocaine, xylocaine, tetracaine, procaine, short term vasodilators, papaverine, adenosine, nitric oxide donor agents, calcium channel blocker agents, sodium channel blocker agents and adenosine regulating agents.