Patent ID: 8552172

Claim:
An oligomer for ameliorating DMD, the oligomer comprising a base sequence selected from the group consisting of: (SEQ ID NO: 6) a) XGC XGC XCX XXX CCA GGX XCA AGX GGG AXA; (SEQ ID NO: 7) b) CXX XXA GXX GCX GCX CXX XXC CAG GXX CAA; (SEQ ID NO: 8) c) CXX XXC XXX XAG XXG CXG CXC XXX XCC AGG; and (SEQ ID NO: 9) d) XXA GXX GCX GCX CXX XXC CAG GXX CAA GXG; wherein X=U or T, wherein the oligomer's base sequence can vary from the above sequence at up to two base positions, and wherein the molecule can bind to a target site to cause exon skipping in an exon of the dystrophin gene.