Patent ID: 8546585

Claim:
A salifying process for preparing eprosartan mesylate, comprising: (i) dissolving or suspending eprosartan in glacial acetic acid, (ii) adding methanesulfonic acid to the mixture of step (i) to obtain a solution of eprosartan mesylate in glacial acetic acid, and (iii) (a) obtaining a solid of eprosartan mesylate by continuously stirring the solution of step (ii) to precipitate the solid and then separating the solid by filtration, (b) obtaining a solid of eprosartan mesylate by concentrating the glacial acetic acid to dry, or (c) obtaining a solid of eprosartan mesylate by adding dropwise an organic ester solvent into the glacial acetic acid under stirring to precipitate the solid and separate the solid.