Patent ID: 7796262

Claim:
A method for determining the concentration of an analyte comprising: providing a first coupled resonator comprising, a micro-ring resonator coupled to an input waveguide and an output waveguide, said output wave guide being optically coupled to a detector; providing a second coupled resonator comprising, a micro-ring resonator coupled to an input waveguide and an output waveguide, said output wave guide being optically coupled to a detector; preparing a sensing micro-ring resonator by applying receptors suitable for binding the analyte of interest to said micro-ring resonator of said first coupled resonator; contacting said micro-ring resonators with a solution or suspension containing said analyte while passing light through said input waveguide; comparing the rate of change in resonance wavelength of said sensing micro-ring resonator in said first coupled resonator to the rate of change in resonance wavelength of the micro-ring resonator in the second coupled resonator thereby determining the presence and concentration of said analyte.