Patent ID: 8420695

Claim:
A compound of the following formula: wherein X is N or CH; Y is N or CR 2 ; Z is N or CR 3 ; R 1 is aryl or heteroaryl, wherein said aryl and heteroaryl groups are optionally substituted on either the carbon or the heteroatom with one to three substituents independently selected from the group consisting of halo, hydroxyl, cyano, SO 2 R 4 , C 1-6 alkyl and heterocyclyl; wherein said alkyl group is optionally substituted with one to three halo, hydroxyl or cyano, and said heterocyclyl group is optionally substituted on either the carbon or heteroatom with one to three halo, hydroxyl or oxo; R 2 is hydrogen, halo, cyano, C 1-6 alkyl, C 3-6 cycloalkyl, heteroaryl, heterocyclyl, (C═O)heterocyclyl, (C═O)R 4 , (C═O)OR 4 , (C═O)NR 4 R 5 , SO 2 R 4 , SO 2 NR 4 R 5 , NR 4 SO 2 R 5 or SO 2 (heterocyclyl); wherein said alkyl group is optionally substituted with one to three halo, hydroxyl, O(C═O)NR 4 R 5 , heteroaryl, heterocyclyl or NR 4 R 5 ; said heterocyclyl groups are optionally substituted on either the carbon or heteroatom with one to two groups independently selected from the group consisting of C 1-3 alkyl, hydroxyl and oxo; and said heteroaryl groups are optionally substituted on either the carbon or heteroatom with C 1-6 alkyl; R 3 is hydrogen or C 1-6 alkyl, wherein said alkyl group is optionally substituted with one to three halo or hydroxyl; R 4 is hydrogen or C 1-6 alkyl; R 5 is hydrogen or C 1-6 alkyl; or a pharmaceutically acceptable salt thereof.