Patent ID: 7220738

Claim:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein A is H, OH, O—(C 1 –C 6 alkyl), O—(C 1 –C 4 alkaryl), or O—(C 6 –C 12 aryl); W is O, S, or NR 1 , wherein R 1 is H, C 1 –C 6 alkyl, or C 1 –C 4 alkaryl; X is H or COR 2 , wherein R 2 is C 1 –C 6 alkyl, which can be substituted with 1–5 OH groups, O—(C 3 –C 7 alkyl), which can be substituted with 1–4 OH groups, C 6 –C 12 aryl, or C 1 –C 4 alkaryl, wherein each alkyl carbon is bound to no more than one oxygen atom; Z is H, Hal, or OR 3 , wherein R 3 is C 1 –C 6 alkyl, C 6 –C 12 aryl, or C 1 –C 4 alkaryl; R 4 is OR 5 , SR 5 , or NR 5 R 6 , wherein R 5 is defined below in relation to R 7 and R 6 is H, C 1 –C 6 alkyl, C 6 –C 12 aryl, C 1 –C 4 alkaryl, COR 9 , CO 2 R 9 , CONHR 9 , CSR 9 , COSR 9 , CSOR 9 , CSNHR 9 , SO 2 R 9 , or SO 2 NHR 9 , wherein R 9 is C 1 –C 6 alkyl, C 6 –C 12 aryl, or C 1 –C 4 alkaryl; and Y is (CR 11 R 12 ) n NR 7 R 8 , wherein n is 0 or 1, R 7 and R 5 together represent a bond or form a substituted or unsubstituted C 1 –C 4 linkage, R 8 is H, C 1 –C 6 alkyl, C 6 –C 12 aryl, C 1 –C 4 alkaryl, COR 10 , CO 2 R 10 , CONHR 10 , CSR 10 , COSR 10 , CSOR 10 , CSNHR 10 , SO 2 R 10 , or SO 2 NHR 10 , wherein R 10 is C 1 –C 6 alkyl, C 6 –C 12 aryl, or C 1 –C 4 alkaryl, or R 8 does not exist and a double bond is formed between N and an R 5 –R 7 C 1 carbon linkage, each of R 11 and R 12 is, independently, H, C 1 –C 6 alkyl, or C 1 –C 4 alkaryl, or R 12 does not exist and a double bond is formed between N and the carbon bearing R 11 .