Patent ID: 6887885

Claim:
A compound of formula I: wherein: X 1 represents hydrogen, halogen, C 1-6 alkyl, trifluoromethyl or C 1-6 alkoxy; X 2 hydrogen or halogen; Y represents a chemical bond, an oxygen atom, or a â€”NHâ€” linkage; Z represents a group selected from phenyl, naphthyl, pyridinyl, quinolinyl, isoquinolinyl, pyridazinyl, pyrimidinyl, pyrazinyl, furyl, benzofuryl, dibenzofuryl, thienyl, benzthienyl, pyrrolyl, indolyl, pyrazolyl, indazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, imidazoly, benzimidazolyl, thiadiazolyl, triazolyl and tetrazolyl, which is unsubstituted or substituted with one or more groups selected from C 1-6 alkyl, adamantyl, phenyl, halogen, C 1-6 haloalkyl, C 1-6 aminoalkyl, trifluoromethyl, hydroxy, C 1-6 alkoxy, aryloxy, keto, C 1-3 alkylenedioxy, nitro, cyano, carboxy, C 2-6 alkoxycarbonyl, C 2-6 alkoxycarbonyl(C 1-6 )alkyl, C 2-6 alkylcarbonyloxy, arylcarbonyloxy, aminocarbonyloxy, C 2-6 alkylcarbonyl, arylcarbonyl, C 1-6 alkylthio, C 1-6 alkylsulphinyl, C 1-6 alkylsulphonyl, arylsulphonyl, â€”NR v R w ,â€”NR v COR w , â€”NR v CO 2 R w , â€”NR v SO 2 R w , â€”CH 2 NR v SO 2 R w , â€”NHCONR v R w , â€”CONR v R w , â€”SO 2 NR v R w and â€”CH 2 SO 2 NR v R w , in which R v and R w independently represent hydrogen, C 1-6 alkyl, phenyl or phenyl(C 1-6 )alkyl; R 1 represents C 1-6 alkyl, phenyl, naphthyl, pyridinyl, quinolinyl, isoquinolinyl , pyridazinyl, pyrimidinyl, pyrazinyl, furyl, benzofuryl, dibenzofuryl, thienyl, benzthienyl, pyrrolyl indolyl, pyrazolyl, indazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, imidazolyl, benzimidazolyl, thiadiazolyl, triazolyl, tetrazolyl, trifluoromethyl, â€”SO 2 R a , â€”SO 2 NR a R b , â€”COR a , or â€”CONR a R b ; and R a and R b independently represent hydrogen, C 1-6 alkyl, phenyl, naphthyl, pyridinyl, quinolinyl, isoquinolinyl, pyridazinyl, pyrimidinyl, pyrazinyl, furyl, benzofuryl, dibenzofuryl, thienyl, benzthienyl, pyrrolyl, indolyl, pyrazolyl, indazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, imidazolyl, benzimidazolyl, thiadiazolyl, triazolyl, tetrazolyl; or a pharmaceutically acceptable salt thereof.