Patent ID: 7022341

Claim:
A bilayer tablet consisting of a combination of an antihistaminic-effective amount of epinastine or a pharmaceutically acceptable salt thereof and a decongestant-effective amount of pseudoephedrine or a pharmaceutically acceptable salt thereof and additional pharmaceutically acceptable carriers or excipients and may additionally contain a tablet coating C consisting of pharmaceutically acceptable excipients, with the proviso that the composition does not contain a leukotriene antagonist, wherein a first layer A, providing for the sustained release of pseudoephedrine, comprises a decongestant-effective amount of pseudoephedrine or a pharmaceutically acceptable salt thereof in a matrix of a swellable hydrophilic polymer and wherein a second layer B, providing for the immediate release of epinastine, comprises an antihistaminic-effective amount of epinastine or a pharmaceutically acceptable salt thereof and wherein the epinastine layer is prepared by direct compression.