Patent ID: 7265114

Claim:
A compound of the formula: or a salt, a diastereomeric mixture, an enantiomer, a tautomer, or a racemic mixture thereof; wherein: R 1 in each occurrence is selected independently from H; linear or branched alkyl with up to 10 carbon atoms; cycloalkyl with up to 10 carbon atoms; or (CH 2 ) x CN, wherein x is 0 or 1; E is CH or N; n is 0 or 1; X 1 is selected from H, m-F, m-Cl, m-Br, m-I, m-SO 2 R 1 , m-SO 2 OR 1 , or m-NC(O)R 1 ; X 2 is selected from H, o-R 1 , p-OR 1 , p-SR 1 , p-F, p-Cl, p-Br, p-CF 3 , p-C(O)OR 1 , p-NC(O)R 1 , p-(4-morpholinyl), or p-(4-methyl-1-piperazinyl); A is NR 1 or O; Y 1 is selected from cycloalkyl with up to 10 carbon atoms, cycloalkyl with up to 10 carbon atoms substituted with at least one substituent R 1 , linear or branched alkyl with up to 10 carbon atoms, CH 2 R 1 , (CHR 1 ) y OR 1 , wherein y is an integer from 1 to 3, or or AY 1 is wherein x is an integer from 3 to 5; and D is NR 1 and Y 2 is selected from cycloalkyl with up to 10 carbon atoms, cycloalkyl with up to 10 carbon atoms substituted with at least one substituent R 1 , linear or branched alkyl with up to 10 carbon atoms, CH 2 R 1 , wherein x is an integer from 3 to 5, or or DY 2 is selected from C(O)R 1 , C(O)OR 1 , pyridinyl, aryl, and wherein q is an integer from 0 to 6.