Patent ID: 8314093

Claim:
A method for treating an inflammatory disorder, an autoimmune disorder, or both, comprising administering to a subject having the disorder, an effective amount of a compound according to the formula: or a stereoisomer, salt, or N-oxide thereof, wherein: Y is selected from the group consisting of S, O, SO, SO 2 , and C(R 7 ) 2 ; each R 35 is independently selected from the group consisting of hydrogen, (C 1 -C 4 )alkyl, and halo, or both R 35 together with the carbon to which they are attached form a carbonyl group; W is selected from the group consisting of C═O, C═S, C═NH, C(R 7 ) 2 , and NR 37 ; Z is C═O or NR 37 , provided that Z and W are not both NR 37 and provided that when Z is C═O, then W is C(R 7 ) 2 or NR 37 ; X is CH or N; each R 31 is independently (C 1 -C 4 )alkyl or both R 31 together form a (C 1 -C 2 )alkyleno group optionally substituted with one to two (C 1 -C 4 )alkyl groups or substituted with one (C 3 -C 7 ) spirocycloalkyl group; each R 7 is independently hydrogen or (C 1 -C 4 )alkyl; and R 37 is hydrogen or methyl optionally substituted with phenyl or pyridyl, wherein said phenyl or pyridyl is optionally substituted with (C 1 -C 4 )alkoxy.