Patent ID: 8022193

Claim:
An oligomeric compound comprising at least one monomer having Formula IX: wherein independently for each of said monomers having Formula IX: Bx is a heterocyclic base moiety; T 3 and T 4 are each, independently, an internucleoside linking group linking the monomer to the oligomeric compound or one of T 3 and T 4 is an internucleoside linking group linking the monomer to the oligomeric compound and the other of T 3 and T 4 is H, a hydroxyl protecting group or a linked conjugate group; Z is C 1 -C 6 alkyl or substituted C 1 -C 6 alkyl; each substituted group is, independently, mono or poly substituted with optionally protected substituent groups independently selected from fluoro, OJ 1 , NJ 1 J 2 , SJ 1 and CN, wherein each J 1 and J 2 is, independently, H, C 1 -C 6 alkyl or a protecting group; and wherein said oligomeric compound comprises from about 8 to about 40 nucleosides and/or modified nucleosides or mimetics in length.