Patent ID: 8034327

Claim:
A hyperglycosylated IL-7 composition, wherein said composition comprises a mammalian IL-7 polypeptide having at least three glycosylated amino acid residues, an average isoelectric point less than 6.5, an average molecular weight greater than 27 KDa as determined by SDS gel electrophoresis and the following three disulfide bridges: Cys: 1-4 (Cys2-Cys92); 2-5 (Cys34-Cys129); 3-6 (Cys47-Cys141) and a pharmaceutically acceptable carrier, excipient or diluent, wherein said glycosylated amino acid residues and disulfide bridges in said mammalian IL-7 polypeptide are found at amino acid residues corresponding to those of SEQ ID NO: 1.