Patent ID: 7759338

Claim:
A compound represented by the following formula: or an enantiomer, racemic mixture, or pharmaceutically acceptable salt thereof; wherein: R 1 is one of the following: 1 adamantyl, 2-adamantyl, bicyclo[2.2.1]heptan-1-yl, bicyclo[2.2.1]heptan-2-yl, bicyclo[2.2.1]heptan-7-yl, benzo[1,3]dioxol-4-yl, benzo[1,3]dioxol-5-yl, 1,3-dihydroisobenzofuran-4-yl, or 1,3-dihydroisobenzofuran-5-yl; R 2 is one of the following; R 3 is one of the following: bromo, trifluoromethyl, chloro, cyclopropyl, isopropoxy, alkylsulfonyl, 2-thienyl, or 3-thienyl; R 4 is Me, H, or one of the following: R 5 is selected from the group consisting of 2 (2′-imidazolyl)phenyl, 3-(2′-imidazolyl)phenyl, 4-(2′-imidazolyl)phenyl, 2-(4′-imidazolyl)phenyl, 3-(4′-imidazolyl)phenyl, 4-(4′-imidazolyl)phenyl, 2-fluorophenyl, 3-fluorophenyl, 4-fluorophenyl, 2-imidazolyl, 4-imidazolyl, 2-imidazolylmethyl, 4-imidazolylmethyl, 2-alkanoylaminophenyl, 3-alkanoylaminophenyl, 4-alkanoylaminophenyl, 2-alkylcarbonylaminophenyl, 3-alkylcarbonylaminophenyl, 4-alkylcarbonylaminophenyl, 4-(4-morpholinylcarbonylamino)phenyl, 3-(4-morpholinylcarbonylamino)phenyl, 2-(4-morpholinylcarbonylamino)phenyl, 4-(3-morpholin-4-ylpropionylamino)phenyl, 3-(3-morpholin-4-ylpropionylamino)phenyl, 2-(3-morpholin-4-ylpropionylamino)phenyl, 2-(2-morpholin-4-ylethoxycarbonylamino)phenyl, 3-(2-morpholin-4-ylethoxycarbonylamino)phenyl, 4-(2-morpholin-4-ylethoxycarbonylamino)phenyl, 2-[2-(2-hydroxyethoxy)ethoxycarbonylamino]phenyl, 3-[2-(2-hydroxyethoxy)ethoxycarbonylamino]phenyl, 4-[2-(2-hydroxyethoxy)ethoxycarbonylamino]phenyl, 2-[2-(2-methoxyethoxy)ethoxycarbonylamino]phenyl, 3-[2-(2-methoxyethoxy)ethoxycarbonylamino]phenyl, and 4-[2-(2-methoxyethoxy)ethoxycarbonylamino]phenyl; and R 6 is H, Br, F, OMe, OBn, or one of the following: biphenyl-2-ylmethyl, 3′-bromobiphenyl-2-ylmethyl, 3′-fluorobiphenyl-2-ylmethyl, 3′-methoxybiphenyl-2-ylmethyl, 3′-benzyloxybiphenyl-2-ylmethyl, 3′,5′-difluorobiphenyl-2-ylmethyl, 3′-benzo[1,3]dioxol-4-ylbiphenyl-2-ylmethyl, 3′-benzo[1,3]dioxol-5-ylbiphenyl-2-ylmethyl, 3′-isopropoxybiphenyl-2-ylmethyl, 3′-(N-tert-butylcarbonyl)biphenyl-2-ylmethyl, 3′-tert-butylcarbonylbiphenyl-2-ylmethyl, 3′-[2-(2-hydroxyethoxy)ethoxy]biphenyl-2-ylmethyl, 3′-[2-(2-methoxyethoxy)ethoxy]biphenyl-2-ylmethyl, or 3′-sulfamoylbiphenyl-2-methyl.