Patent ID: 7459431

Claim:
A composition suitable as a substitute for plasma comprising a solution of saline in a physiologically acceptable concentration and a protein having a colloid osmotic function wherein the protein having a colloid osmotic function is a recombinant gelatin-like protein consisting essentially of repeats of Gly-Xaa-Yaa triplets and comprising a molecular weight of between 10,000 and 80,000 Daltons and at least one stretch of at least 30 consecutive Gly-Xaa-Yaa triplets, wherein at least 5% of the total number of protein amino acid residues in the gelatin-like protein are proline residues, wherein the gelatin-like protein is free from globular domains and does not comprise stretches of more than 20 amino acids without a proline residue wherein less than 2% of the amino acid residues, optionally less than 1%, in the gelatin-like protein are hydroxyproline residues and wherein said recombinant gelatin-like protein is present in the range of from 2 percent to 8 percent by weight of the composition.