Patent ID: 7662786

Claim:
A compound of the formula A-B-D-E-F-(G) r -(K) s -L wherein r and s are 0; A is a proline derivative of Formula II a , wherein n a is 0 to 2; R a is hydrogen or unsubstituted normal or branched C 1 -C 3 -alkyl; R 1 a is hydrogen; or R a and R 1 a together form a propylene bridge; and R 2 a ,R 3 a , R 4 a , and R 5 a are each hydrogen; or an α-amino acid derivative of Formula III a , wherein R a is hydrogen or unsubstituted C 1 -C 3 -alkyl; R 1 a is C 1 -C 3 -alkyl; R 6 a is methyl, hydroxyl- or methoxy-substituted C 1 -C 3 -alkyl, phenyl, or fluorine- or methoxy-substituted phenyl; and R 7 a is hydrogen or C 1 -C 3 -alkyl; or an α-amino acid derivative of Formula IV a , wherein m a is 1 or 2; R 7 a is hydrogen or methyl; and R a is hydrogen or methyl; or an α-amino acid of formula VII a , wherein R a is methyl; R 1 a is hydrogen; and R 2 a , R 3 a , R 4 a , and R 5 a are each methyl; or an α-amino acid residue of formula X a , wherein n a is 2 or 3; R 7 a is methyl; and R a is methyl; B is valyl, isoleucyl, or 2-tert-butylglycyl; D is N-methylvalyl or N-methylisoleucyl; E is prolyl, thiazolidinyl-4-carbonyl or 3,4-didehydroprolyl; F is prolyl; and L is N-benzylamide, N-methoxy-N-benzylamide, tert-butylamide, tert-butyl ester, N-methoxy-N-methylamide, isopropylamide, 5-phenyl isoxasolidinyl, isoxazolidinyl, pentylamide, (R) or (S) phenethylamide, -O-tert-butyl, isoxazolidinyl, 5-phenyl isoxazolidinyl,