Patent ID: 8450378

Claim:
A method of inactivating acid stable non-enveloped virus particles, the method comprising: contacting acid stable non-enveloped virus particles with a virucidally-enhanced alcoholic composition comprising at least about 50 percent by weight of a C 1-6 alcohol, based upon the total weight of the alcoholic composition, and an efficacy-enhancing amount of one or more enhancers selected from the group consisting of cationic oligomers and polymers, chaotropic agents, and mixtures thereof, with the proviso that when the alcoholic composition comprises at least one cationic oligomer or polymer, the composition further comprises at least one enhancer selected from the group consisting of chaotropic agents, zinc compounds, and copper compounds, wherein said chaotropic agent comprises urea, thiourea, guanidine HC1, guanidine thiocyanate, aminoguanidine HC1, aminoguanidine bicarbonate, guanidine carbonate, guanidine phosphate, or mixtures thereof.