Patent ID: 8563549

Claim:
A compound having Formula I: or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, wherein, W is CR w or N, wherein R w is selected from the group consisting of (1) hydrogen, (2) cyano, (3) halogen, (4) methyl, (5) trifluoromethyl, (6) sulfonamido; R 1 is substituted or unsubstituted morpholinyl; R 2 is selected from the group consisting (1) hydrogen, (2) cyano, (3) nitro, (4) halogen, (5) hydroxy, (6) amino, (7) substituted and unsubstituted alkyl, (8) —COR 2a , and (9) —NR 2a COR 2b , wherein R 2a , and R 2b are independently selected from the group consisting of (a) hydrogen, and (b) substituted or unsubstituted alkyl; R 3 is selected from the group consisting of (1) hydrogen, (2) cyano, (3) nitro, (4) halogen, (5) substituted and unsubstituted alkyl, (6) substituted and unsubstituted alkenyl, (7) substituted and unsubstituted alkynyl, (8) substituted and unsubstituted aryl, (9) substituted and unsubstituted heteroaryl, (10) substituted and unsubstituted heterocyclyl, (11) substituted and unsubstituted cycloalkyl, (12) —COR 3a , (13) —NR 3a R 3b , (14) —NR 3a COR 3b , (15) —NR 3a SO 2 R 3b , (16) —OR 3a , (17) —SR 3a , (18) —SOR 3a , (19) —SO 2 R 3a , and (20) —SO 2 NR 3a R 3b , wherein R 3a , and R 3b are independently selected from the group consisting of (a) hydrogen, (b) substituted or unsubstituted alkyl, (c) substituted and unsubstituted aryl, (d) substituted and unsubstituted heteroaryl, (e) substituted and unsubstituted heterocyclyl, and (f) substituted and unsubstituted cycloalkyl; and R 4 is selected from the group consisting of (1) hydrogen, and (2) halogen.