Patent ID: 8377031

Claim:
A method, comprising: monitoring, using one or more processors, a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and an automatic administration of a medication, wherein the plurality of parameters monitored includes an analyte level; detecting an adverse condition associated with the monitored physiological condition or the automatic medication administration deviating from a predetermined safety level of medication delivery of the closed loop control operation; initiating a non-zero pre-programmed medication delivery rate when the adverse condition is detected, wherein the non-zero pre-programmed medication delivery rate is different than the automatic administration of medication and wherein the non-zero pre-programmed medication delivery rate is based on the predetermined safety level of medication delivery; estimating medication on board information based on the monitored administration of the medication and outputting a notification based on the estimated medication on board information; modifying the initiated non-zero pre-programmed medication delivery rate using the estimated medication on board information; determining an acceleration of a level of a monitored analyte change; and updating the medication delivery rate based on the determined acceleration of the level of the monitored analyte change.