Patent ID: 7144716

Claim:
A process for producing a product by enzymatic treatment of a particulate substrate comprising: providing a particulate feed substrate, providing a particulate, immobilized enzyme, reacting the particulate feed substrate with the particulate, immobilized enzyme in a bioreactor to produce an effluent process liquor containing the effluent particulate, immobilized enzyme, a product of the reaction and an effluent particulate substrate, which has a particle size distribution different from the effluent particulate, immobilized enzyme, treating the process liquor to produce a slurry, subjecting the slurry to at least one of screening, continuous centrifuging or hydrocycloning to separate the effluent particulate substrate from the effluent particulate, immobilized enzyme, subjecting the slurry to hydrocycloning to separate the particulate, immobilized enzyme from the product, and recycling the particulate, immobilized enzyme.