Patent ID: 6949651

Claim:
A compound of the formula (I): wherein A is —NR(C═O) or —(C═O)NR; X is selected from —N═, —S—, or —CR 10 —; Y is selected from —N═, —S—, or —CR 10 —; with the proviso that when Y is S, X is not S; dashed lines represent optional double bonds; ring B is selected from the group consisting of: wherein each R, R 1 , R 2 , R 3 , R 5 , R 6 , R 9 , and R 10 are the same or different, where ever they appear, and each is independently selected from the group consisting of (C 1 -C 6 )alkyl-, (C 2 -C 6 )alkenyl-, (C 2 -C 6 )alkynyl-, (C 3 -C 10 )cycloalkyl-, (C 6 -C 10 )aryl-, (C 1 -C 10 )heteroaryl-, (C 3 -C 10 )cycloalkyl-(C 1 -C 6 )alkyl-, (C 6 -C 10 )aryl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heterocyclyl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heteroaryl-(C 1 -C 6 )alkyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkenyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkynyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkynyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkynyl-, (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkynyl-; wherein each of the aforesaid group members, (C 1 -C 6 )alkyl-, (C 2 -C 6 )alkenyl-, (C 2 -C 6 )alkynyl-, (C 3 -C 10 )cycloalkyl-, (C 6 -C 10 )aryl-, (C 1 -C 10 )heterocyclyl-, (C 1 -C 10 )heteroaryl-, (C 3 -C 10 )cycloalkyl-(C 1 -C 6 )alkyl-, (C 6 -C 10 )aryl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heterocyclyl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heteroaryl-(C 1 -C 6 )alkyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkenyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkynyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkynyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkynyl-, and (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkynyl-, may be optionally independently substituted with one to three substituents selected from the group consisting of hydrogen, halogen, hydroxy, —CN, (C 1 -C 4 )alkyl-, (C 1 -C 4 )alkoxy-, CF 3 —, CF 3 O—, (C 6 -C 10 )aryl-, (C 1 -C 10 )heteroaryl-, (C 6 -C 10 )aryl-(C 1 -C 4 )alkyl-, (C 1 -C 10 )heteroaryl-(C 1 -C 4 )alkyl-, HO(C═O)—, (C 1 -C 4 )alkyl-(O)(C═O)—, (C 1 -C 4 )alkyl-(O)(C═O)(C 1 -C 4 )alkyl-, (C 1 -C 4 )alkyl-(C═O)—, (C 1 -C 4 )alkyl-(C═O)(C 1 -C 4 )alkyl-, and NR 7 R 8 wherein R 7 and R 8 are independently selected from hydrogen, (C 1 -C 6 )alkyl; R, R 3 , R 5 , R 6 , R 9 , and R 10 may further be hydrogen; R 4 is selected from the group consisting of hydrogen and (C 1 -C 6 )alkyl-, and R 4 may be optionally substituted with one to three substituents selected from the group consisting of halogen, hydroxy, —CN, CF 3 —, and CF 3 O—; m is an integer from 0-3; or a pharmaceutically acceptable salt thereof.