Patent ID: 8236785

Claim:
A method of controlled ovarian hyperstimulation in a mammalian female, said method comprising administering to said female a combination of (i) an FSH substance selected from the group consisting of uFSH and recFSH in an effective amount to stimulate follicular development and (ii) a steroid in an effective amount to inhibit or suppress the secretion of luteinising hormone, the steroid being selected from the group consisting of: substances represented by the following formula in which formula R 1 , R 2 , R 3 , and R 4 independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R 5 , R 6 , and R 7 is a hydroxyl group; no more than three of R 1 , R 2 , R 3 , and R 4 are hydrogen atoms; derivatives of the aforementioned steroid substances wherein the hydrogen atom of at least one of the hydroxyl groups has been substituted by an acyl radical of a hydrocarbon carboxylic, sulfonic or sulfamic acid of 1-25 carbon atoms; tetrahydrofuranyl; tetrahydropyranal; or a straight or branched chain glycosidic residue containing 1-20 glycosidic units per residue; and mixtures of one or more of the aforementioned steroid substances or derivatives.