Patent ID: 7579346

Claim:
A compound of formula I in which D denotes thienyl which is unsubstituted or mono- or polysubstituted by Hal, A, OR 2 , N(R 2 ) 2 , NO 2 , CN, COOR 2 or CON(R 2 ) 2 , X denotes —C═O, W denotes —[C(R 3 ) 2 ] n —, R 1 denotes H or A, which may be substituted by OR 3 , S(O) n R 3 , N(R 3 ) 2 , CN, COOR 3 , CON(R 3 ) 2 , OCON(R 3 ) 2 , N(R 3 )COOR 3 , N(R 3 )CON(R 3 ) 2 , N(R 3 )SO 2 R 3 , SO 2 N(R 3 ) 2 or —C≡C—, R 2 denotes H, A, —[C(R 3 ) 2 ] n —Ar′, —[C(R 3 ) 2 ] n -Het′, —[C(R 3 ) 2 ] n -cycloalkyl, —[C(R 3 ) 2 ] n —N(R 3 ) 2 or —[C(R 3 ) 2 ] n —OR 3 , R 3 denotes H or A, Y denotes Ar-diyl, T denotes a mono- or bicyclic saturated, unsaturated or aromatic carbo- or heterocycle having 0 to 4 N, O and/or S atoms which is mono- or disubstituted by ═O, ═S, ═NR 2 , ═N—CN, ═N—NO 2 , ═NOR 2 , ═NCOR 2 , ═NCOOR 2 , and/or ═NOCOR 2 and may furthermore be mono-, di- or trisubstituted by R 2 , Hal, A, —[C(R 3 ) 2 ] n —Ar, —[C(R 3 ) 2 ] n -Het, —[C(R 3 ) 2 ] n -cycloalkyl, OR 2 , N(R 2 ) 2 , NO 2 , CN, COOR 2 , CON(R 2 ) 2 , NR 2 COA, NR 2 CON(R 2 ) 2 , NR 2 SO 2 A, COR 2 , SO 2 NR 2 and/or S(O) n A, A denotes unbranched or branched alkyl having 1-10 C atoms, in which one or two CH 2 groups may be replaced by O or S atoms and/or by —CH═CH— groups and/or 1-7 H atoms may be replaced by F, Ar denotes phenyl, naphthyl or biphenyl, each of which is unsubstituted or mono-, di- or trisubstituted by Hal, A, OR 2 , N(R 2 ) 2 , NO 2 , CN, COOR 2 , CON(R 2 ) 2 , NR 2 COA, NR 2 CON(R 2 ) 2 , NR 2 SO 2 A, COR 2 , SO 2 N(R 2 ) 2 , S(O) n A, —[C(R 3 ) 2 ] n —COOR 2 or —O—[C(R 3 ) 2 ] o —COOR 2 , Ar′ denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, A, OR 3 , N(R 3 ) 2 , NO 2 , CN, COOR 3 , CON(R 3 ) 2 , NR 3 COA, NR 3 CON(R 3 ) 2 , NR 3 SO 2 A, COR 3 , SO 2 N(R 3 ) 2 , S(O) n A, —[C(R 3 ) 2 ] n —COOR 3 or —O—[C(R 3 ) 2 ] o —COOR 3 , Het denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono-, di- or trisubstituted by carbonyl oxygen, ═S, ═N(R 2 ) 2 , Hal, A, —[C(R 3 ) 2 ] n —Ar, —[C(R 3 ) 2 ] n -Het′, —[C(R 3 ) 2 ] n -cycloalkyl, —[C(R 3 ) 2 ] n —OR 2 , —[C(R 3 ) 2 ] n —N(R 3 ) 2 , NO 2 , CN, —[C(R 3 ) 2 ] n —COOR 2′ , —[C(R 3 ) 2 ] n —CON(R 2 ) 2 , —[C(R 3 ) 2 ] n —NR 2 COA, NR 2 CON(R 2 ) 2 , —[C(R 3 ) 2 ] n —NR 2 SO 2 A, COR 2 , SO 2 NR 2 and/or S(O) n A, Het′ denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono- or disubstituted by carbonyl oxygen, ═S, ═N(R 3 ) 2 , Hal, A, OR 3 , N(R 3 ) 2 , NO 2 , CN, COOR 3 , CON(R 3 ) 2 , NR 3 COA, NR 3 CON(R 3 ) 2 , NR 3 SO 2 A, COR 3 , SO 2 NR 3 and/or S(O) n A, Hal denotes F, Cl, Br or I, m denotes 1 or 2, n denotes 0, 1 or 2, and o denotes 1, 2 or 3, or a pharmaceutically acceptable salt, or stereoisomer thereof, or a mixture thereof.