Patent ID: 6841701

Claim:
Inhibitors for the coagulation factor Xa of the formula: in which the substituent Y occurs in the 3- or 4-position and is an amidino group in which R 5 is selected from the group consisting of H, OH, —CO—R 7 and —COO—R 7 , where R 7 is selected from a branched or unbranched alkyl having 1-16 C atoms, a substituted or unsubstituted aryl or heteroaryl group and a substituted or unsubstituted aralkyl or heteroaralkyl group, X is CH or N, R 1 is H or a branched or unbranched alkyl having 1-8 C atoms or (CH 2 ) n —OH where n=1-5, R 2 is H or a branched or unbranched alkyl having 1-8 C atoms, R 3 is a branched or unbranched alkyl having 1-8 C atoms or (CH 2 ) n —O—R 6 , where N=1-5 and R 6 is a branched or unbranched alkyl having 1-6 C atoms, a substituted or unsubstituted aryl or heteroaryl group or a substituted or an unsubstituted aralkyl or heteroaralkyl group and R 4 is selected from the group consisting of —SO 2 —R 8 , —CO—R 8 , —COO—R 8 and H, where R 8 is a branched or unbranched alkyl having 1-16 C atoms, a substituted or an unsubstituted aryl or heteroaryl group, a substituted or unsubstituted aralkyl or heteroaralkyl group, an adamantyl group, a camphoryl group or a cyclohexylmethyl group.