Patent ID: 8709404

Claim:
A method for treating cancer having a primary tumor in a human patient, comprising (a) providing lymphocytes obtained from sentinel lymph nodes from the patient, wherein the sentinel lymph nodes are the first lymph nodes in the lymphatic system that receive lymphatic drainage from the primary tumor area; (b) expanding the lymphocytes in vitro, wherein the lymphocytes are stimulated in vitro by addition of a stimulating agent selected from the group consisting of IL-2, IL-12, anti-CD3 antibody, and anti-CD28 antibody and are exposed to recombinant tumor antigen and/or autologous tumor extract, optionally presented with antigen presenting cells selected from B-cells, macrophages, monocytes, dendritic cells, or Langerhans cells; and (c) transferring the expanded lymphocytes into the patient.