Patent ID: 7230081

Claim:
A conjugate of an interferon gamma (IFNG) polypeptide variant, said conjugate exhibiting interferon gamma receptor binding activity and comprising an N-linked sugar moiety covalently attached to an introduced N-glycosylation site of said IFNG polypeptide variant, wherein a) said IFNG polypeptide variant consists of an amino acid sequence that differs by 1 to 15 amino acid residues from that of wildtype human IFNG (huIFNG) shown in SEQ ID NO: 2, or a fragment thereof which is C-terminally truncated by 1 to 15 amino acid residues; and b) said introduced N-glycosylation site is located within the 118 N-terminal amino acid residues of the IFNG polypeptide variant relative to SEQ ID NO: 2.