Patent ID: 7705035

Claim:
A compound of Formula I or a pharmaceutically acceptable salt thereof, wherein: X is —COOH or tetrazol-5-yl; each of A, B and C is independently selected from N, CH and C(R 3 ), with the proviso that not more than one of A, B or C may be N; D is —C(R) 2 —, wherein each R is independently selected from the group consisting of: hydrogen, C 1-4 alkyl, C 1-4 fluoroalkyl, C 1-4 alkoxy, C 1-4 fluoroalkoxy and acetyl; Ar 1 and Ar 2 are independently selected from the group consisting of: aryl, heteroaryl and heterocyclyl, wherein the aryl of Ar 1 and Ar 2 is independently selected from phenyl and naphthyl, the heteroaryl of Ar 1 and Ar 2 is independently selected from pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, pyridyl, oxazolyl, oxadiazolyl, thiadiazolyl, thiazolyl, imidazolyl, triazolyl, tetrazolyl, furanyl, triazinyl, thienyl, pyrimidyl, pyridazinyl, pyrazinyl, benzoxazolyl, benzothiazolyl, benzimidazolyl, benzofuranyl, benzothiophenyl, furo(2,3-b)pyridyl, quinolyl, indolyl and isoquinolyl, and the heterocyclyl of Ar 1 and Ar 2 is independently selected from pyrrolidinyl, piperidinyl, piperazinyl, imidazolidinyl, 2,3-dihydrofuro(2,3-b)pyridyl, benzoxazinyl, tetrahydrohydroquinolinyl, tetrahydroisoquinolinyl, and dihydroindolyl, and wherein Ar 1 is optionally substituted with one to three R 1 groups and Ar 2 is optionally substituted with one to three R 2 groups; and each R 1 , R 2 and R 3 is independently selected from the group consisting of: halo, —CN, C 1-4 alkyl, C 1-4 fluoroalkyl, C 1-4 alkoxy, C 1-4 fluoroalkoxy, acetyl, aminocarbonyl and phenyl, R 4 and R 5 are selected from the group consisting of: hydrogen and C 1-4 alkyl, or R 4 and R 5 may be joined together with the atom to which they are attached to form a C 3-6 cycloalkyl group.