Patent ID: 8324384

Claim:
A compound represented by formula I: or a pharmaceutically acceptable salt thereof wherein: a is an integer selected from 1, 2 and 3, and b is an integer selected from 0 and 1, such that the sum of a and b is 2 or 3; each R l represents H or is selected from the group consisting of: halo, CN, OH, NO 2 , CO 2 R a , NR a R b , S(O) p R a , C 1-10 alkyl, C 2-10 alkenyl or C 1-10 alkoxy, the alkyl and alkenyl portions of C 1-10 alkyl, C 2-10 alkenyl and C 1-10 alkoxy being optionally substituted with 1-5 halo atoms; and further optionally substituted with 1 group selected from OH, oxo and C 1-6 alkoxy; p represents 0, 1 or 2; each R a and R b independently represents H or C 1-4 alkyl optionally substituted with 1-5 halo atoms; and further optionally substituted with 1 group selected from OH, oxo and C 1-6 alkoxy; R 2 represents C 1-6 alkyl or C 2-6 alkenyl, each optionally substituted with 1-5 halo atoms, and further optionally substituted with 1 group selected from OH, oxo and C 1-6 alkoxy; each R 3 represents H or halo, or 1-3 R 3 groups represent H or halo and the remainder represent a member selected from the group consisting of: CN; OH; NO 2 ; CO 2 R a ; NR a R b ; S(O) p R a ; phenyl or 5-6 membered heteroaryl containing 1-3 nitrogen atoms and 0-1 oxygen or sulfur atom, said phenyl and heteroaryl being optionally substituted with 1-3 halo atoms and 1-2 members selected from the group consisting of: C 1-3 alkyl, C 1-3 alkoxy, haloC 1-3 alkyl and haloC 1-3 alkoxy; C 1-10 alkyl; C 2-10 alkenyl and C 1-10 alkoxy, the alkyl and alkenyl portions of C 1-10 alkyl, C 2-10 alkenyl and C 1-10 alkoxy being optionally substituted with 1-5 halo atoms; and further optionally substituted with 1 group selected from OH, oxo, NR a R b , and C 1-6 alkoxy; each R 4 independently represents H or is selected from the group consisting of: halo, OH, C 1-4 alkyl, OC 1-4 alkyl, haloC 1-4 alkyl and haloOC 1-4 alkyl; m represents 0, 1 or 2; when m represents 0, Z represents tetrazolyl; when m represents 1, Z represents a member selected from the group consisting of: CO 2 H, SO 3 H, C(O)NH 2 and tetrazolyl; and when m represents 2, Z represents a member selected from the group consisting of: CO 2 H, SO 3 H and C(O)NH 2 .