Patent ID: 7342007

Claim:
A compound of formula (I): wherein: R 1 is selected from H, optionally substituted C 1-3 alkylaryl, optionally substituted C 1-3 alkylheterocycle, optionally substituted alkyl, optionally substituted C 3-6 cycloalkyl, C 2-4 alkylNR a R b , and C 1-4 alkylCOR d , wherein all such optional substitutions are made with 0, 1, 2 or 3 R e ; R a and R b are, at each occurrence independently selected from H, C 1-4 alkyl and C 5-6 cycloalkyl, or R a and R b and the N to which they are attached in combination form a 5 or 6-membered N-linked heterocycle having 2 nitrogen or, 1 nitrogen and 1 oxygen, ring atoms, wherein the non-linked nitrogen is substituted with R c ; R c is, at each occurrence independently selected from H, C 1-3 alkyl, and substituted phenyl with 0, 1, 2, or 3 R e ; R d is, at each occurrence independently selected from C 1-3 alkyl, C 1-3 alkoxy, and NR a R b ; R e is, at each occurrence independently selected from OH, F, Cl, Br, I, CN, NO 2 , CF 3 , C 1-6 alkyl, or C 1-6 alkoxy; R 2 , R 3 , R 6 and R 7 are independently selected from H, optionally substituted 5- or 6-membered aromatic or heteroaromatic ring, said ring having 0, 1, 2 or 3, nitrogen, oxygen or sulfur atoms, but not more than 2 oxygen atoms or 2 sulfur atoms or 1 oxygen and 1 sulfur atom, optionally substituted C 1-3 alkylaryl, optionally substituted C 1-3 alkylheterocycle, optionally substituted C 1-6 alkyl, and optionally substituted C 3-6 cycloalkyl, wherein all such optional substitutions are made with 0, 1, 2, or 3 R e moieties, with the requirement that one or more of R 2 , R 3 , R 6 and R 7 are aromatic or heteroaromatic; R 4 is H, optionally substituted 5- or 6-membered aromatic or heteroaromatic ring, said ring having 0, 1, 2 or 3, nitrogen, oxygen or sulfur atoms, but not more than 2 oxygen atoms or 2 sulfur atoms or 1 oxygen and 1 sulfur atom, C 1-6 alkyl, C 3-6 cycloalkyl, or CR 9 R 10 R 11 ; R 5 is —C 1-6 alkyl, —C 1-3 alkylR 12 or CH(OH)R 13 ; R 9 , R 10 and R 11 are, at each occurrence independently selected from H, F, C 1-4 alkyl, OH, OCH 3 , SH, SCH 3 , and CH 2 SCH 3 ; R 12 is phenyl substituted with 0, 1, 2 or 3 R e ; and R 13 is C 1-6 alkyl or R 12 ; or a pharmaceutically acceptable salt thereof.