Patent ID: 8748370

Claim:
A compound of the general formula (I) R 1 -A-NH—CH(R 2 )—CO—R 3 (I) wherein, R 1 is Ar—X—, where X is (CH 2 ) m —O—CO; (CH 2 ) m —SO 2 —CH═CH—CO; CH═CH—CO; CO-oxirane-CO; CO—CH═CH—CO; CH 2 —CH═CH—CO; or (CH 2 ) m —CO; R 1 is NH 2 —C(NH)—NH—(CH 2 ) m —CO; or R 1 is an acyl residue containing hydroxylated coumarin moiety; A is a bond or is one or more of Val or Leu; R 2 is isopropyl or isobutyl; R 3 is NH—(CH 2 ) m —NH—C(NH)—NH 2 ; R 3 is Phe-NH 2 ; or R 3 is NH—CH(R 4 )—(CH 2 ) m —NH-D, where R 4 is C 1 -C 6 -alkyl, and D is CO—CH═CH—Ar, CO—CH═CH—SO 2 —(CH 2 ) m —Ar, or Cum-Phe-, where Cum is an acyl residue containing hydroxylated coumarin moiety; Ar is aryl or heteroaryl; and m is an integer of 0 to 5; the compound as a single stereoisomer or a mixture of different stereoisomers, or a pharmaceutically acceptable salt thereof.