Patent ID: 7029695

Claim:
A liposomal formulation containing a compound that is: (i) a diester of a compound of formula A where: each ester is 1–25C; YCO is γ-glu or β-asp; G* is phenylglycine; Z is CH 2 , O or S; and X is a hydrocarbon radical which is alkyl (6–8C), benzyl, or naphthyl; or a pharmaceutically acceptable salt thereof; or (ii) a compound of formula I where: R 1 and R 2 are each independently linear or branched alkyl (1–25C), cycloalkyl (6–25C), heterocycle (6–25C), ether or polyether (3–25C), or R 1 and R 2 together have 2–20C atoms and form a macrocycle with the remainder of formula I; and X is as defined above for formula A; or a pharmaceutically acceptable salt thereof where the lipids of the liposomal formulation consist of egg phosphatidylcholine and egg phosphatidylglycerol in a ratio of 0.75–1.25:0.75–1.25 by weight and the ratio of lipids to compound is 3.5–4.5:0.5–1.5 by weight.