Patent ID: 7816353

Claim:
A compound according to Formula III, or a pharmaceutically acceptable salt thereof, wherein: R 1a is selected from halogen, lower perfluoroalkyl, —NO 2 , and optionally substituted C 1-4 alkyl; and R 1b is selected from halogen, —N(R 5 )R 5 , —SR 5 , perfluoroalkyl, and optionally substituted lower alkyl; R 3 is independently selected from —H, halogen, trihalomethyl, —CN, —NO 2 , —OR 5 , —N(R 5 )OR 5 , —ON(R 5 )R 5 , —N(R 5 )N(R 5 )R 5 , —N(R 5 )R 5 , —S(O) 0-2 R 5 , —SO 2 N(R 5 )R 5 , —CO 2 R 5 , —C(O)N(R 5 )R 5 , —N(R 5 )SO 2 R 5 , —N(R 5 )C(O)R 5 , —N(R 5 )CO 2 R 5 , —C(O)R 5 , —C(═NR 7 )N(R 5 )R 5 , —C(═NR 7 )R 5 , —C(═NR 7 )OR 5 , —N(R 5 )C(═NR 7 )N(R 5 )R 5 , optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted aryl, optionally substituted heterocyclyl, optionally substituted heterocyclylalkyl, and optionally substituted arylalkyl; R 5a is H; each R 5 is independently selected from —H, optionally substituted lower alkyl, optionally substituted aryl, optionally substituted lower arylalkyl, optionally substituted heterocyclyl, and optionally substituted lower heterocyclylalkyl; or two of R 5 , together with the atom or respective atoms to which they are attached, can combine to form an optionally substituted three- to seven-membered heterocyclic; each R 6 is independently selected from —H, halogen, trihalomethyl, —CN, —NO 2 , —NH 2 , —OR 5 , —N(R 5 )R 5 , —S(O) 0-2 R 5 , —SO 2 N(R 5 )R 5 , —CO 2 R 5 , —C(O)N(R 5 )R 5 , —N(R 5 )SO 2 R 5 , —N(R 5 )C(O)R 5 , —N(R 5 )CO 2 R 5 , —C(O)R 5 , optionally substituted lower alkyl, optionally substituted aryl, optionally substituted heterocyclyl, optionally substituted heterocyclylalkyl, and optionally substituted arylalkyl; or two of R 6 , together with the atom or atoms to which they are attached, can combine to form one of an optionally substituted three to seven-membered alicylic, and an optionally substituted three to seven-membered heteroalicylic; each R 7 is independently selected from —H, —CN, —NO 2 , —N(R 5 )R 5 , —OR 5 , —S(O) 0-2 R 5 , —SO 2 N(R 5 )R 5 , —CO 2 R 5 , optionally substituted lower alkyl, optionally substituted lower alkenyl, and optionally substituted lower alkynyl; or R 5 and R 7 , together with the atom or atoms to which they are attached, can combine to form a five- to seven-membered optionally substituted heterocyclyl; each of X and Y is independently selected from —C(═O)—, —C(R 6 )R 6 —, —O—, —N(R 5 )—, —C(═NR 7 )—, and —S(O) 0-2 —; provided when X is —O— or —N(R 5 )—, then Y cannot contain phenyl, napthyl, cyclohexyl, dihydronapthyl tetrahydronapthyl, or a five- to six-membered heteroaryl, each optionally substituted; and Q is either ═N— or ═C(H)—.