Patent ID: 7186407

Claim:
A method for treating peripheral artery disease in a patient, said method comprising administering to said patient a therapeutically effective amount of a fibroblast growth factor-2 (FGF-2) or an angiogenically active fragment or angiogenically active mutein thereof, wherein said therapeutically effective amount of said FGF-2 or said angiogenically active fragment or angiogenically active mutein thereof is divided into two doses and a single dose is administered into each leg of said patient within a one hour period, whereby said peripheral artery disease is treated, wherein said FGF-2 comprises the sequence set forth in SEQ ID NO:2, SEQ ID NO:4, SEQ ID NO:6, or SEQ ID NO:8, and wherein said angiogenically active mutein has at least 95% amino acid sequence identity to the FGF-2 sequence set forth in SEQ ID NO:2, SEQ ID NO:4, SEQ ID NO:6, or SEQ ID NO:8.