Patent ID: 6974826

Claim:
A compound of the formula: wherein: R 1 and R 2 together with the aromatic ring bonded thereto comprise a cycloalkyl or cycloalkenyl ring having 3 to 8 carbon atoms that optionally comprises 1 or 2 heteroatoms selected from O, S, NH or N-alkyl, and wherein the cycloalkyl or cycloalkenyl ring is optionally further substituted with one or more groups independently selected from halogen, alkyl, hydroxyl, alkoxy, substituted alkoxy, carboxy, carboalkoxy, alkylcarboxamide, substituted alkylcarboxamide, dialkylcarboxamide, substituted dialkylcarboxamide, amino, mono-substituted amino or di-substituted amino; R 3 and R 4 are independently or together hydrogen, halogen, alkyl, substituted alkyl, haloalkyl, alkoxy, substituted alkoxy, amino, mono-substituted amino, di-substituted amino or haloalkoxy; Ar is Formula (VI), (VII) or (VIII): wherein: R 8 is alkyl, substituted alkyl, alkenyl, haloalkyl, hydroxy, acyloxy, halogen, alkoxy, substituted alkoxy, amino, mono-substituted amino, di-substituted amino, alkylamide or haloalkoxy; and R 9 and R 10 are independently or together hydrogen, halogen, alkyl, substituted alkyl, haloalkyl, alkenyl, substituted alkenyl, alkoxy, hydroxyl, amino, mono-substituted amino, di-substituted amino, alkylamide or haloalkoxy; R 5 is hydrogen, or alkyl; - - - - - represents a bond present or absent; and W, X, Y and Z together form a isoxazolidinedione, 2,4-imidazolidinedione or 2-thioxo-4-imidazolidinedione; or a pharmaceutically acceptable salt thereof.