Patent ID: 8236773

Claim:
A method of treating a C5 complement protein, C5a and/or C5b-9-mediated disorder, the method comprising the step of administering to a patient in need thereof a therapeutically effective amount of a compound having the structure set forth below or a salt thereof: where, indicates a linker Aptamer=fCmGfCfCGfCmGmGfUfCfUfCmAmGmGfCGfCfUmGmAmGfUfCfUmGmAmGfUfUfUAfCfCfUmGfCmG-3T (SEQ ID NO:4), wherein fC and fU=2′-fluoro nucleotides, and mG and rnA=2′-OMe nucleotides and all other nucleotides are 2′-OH and 3T indicates an inverted deoxy thymidine.