Patent ID: 7744559

Claim:
A method of infusing a drug to a target tissue within a target volume, comprising the following steps: inserting an expandable device defining an outer surface into the target volume; inserting at least one sensor between (i) said outer surface of the expandable device and (ii) the tissue in the target volume directly adjacent to and surrounding said outer surface of said expandable device; expanding said expandable device such that the surrounding tissue in the target volume conforms to said outer surface of said expandable device such that at least a portion of said outer surface of said expandable device and an area of the target tissue define an enclosed treatment volume; delivering a drug under a continuous positive pressure to said enclosed treatment volume; measuring a parameter which can be correlated to the degree of conformance between said outer surface of said expandable device and the tissue in the target volume directly adjacent to and surrounding said expandable device; and adjusting the volume of said expandable device based on said measured parameter.