Patent ID: 7404893

Claim:
A chromatography cartridge comprising: a tubular housing having a first wall thickness, the tubular housing including a first open end, a second open end, and an inner volume defined between the first open end and the second open end; a first portion of the tubular housing formed of a first material, and a second portion of the tubular housing formed of a second material, the second portion defining a stripe on an outer surface of the tubular housing, the stripe extending substantially the length of the tubular housing and having a second wall thickness less than the first wall thickness; a plug including an annular groove adapted to receive one of the first open end and the second open end, a first portion of the plug positioned through the open end and into the inner volume and having an outer circumferential surface, a substantial portion of the outer circumferential surface having a length greater than the first wall thickness of the tubular housing and being fused to an inner surface of the tubular housing, and a second portion of the plug positioned outside the inner volume and extending toward the opposite open end, the second portion of the first plug extending along and overlapping a portion of an outer surface of the tubular housing, the plug including an aperture in fluid communication with the inner volume, and a protruding extension through which the aperture extends; a first frit positioned in the inner volume of the tubular housing, the first frit having a first surface oriented substantially parallel to a lateral surface of the first portion of the plug, the first surface of the first frit being in contact with the lateral surface of the first portion of the plug; a second frit positioned in the inner volume of the tubular housing and adjacent the second open end; and a chromatography medium positioned between the first frit and the second frit.