Patent ID: 8114865

Claim:
A compound of formula (I): wherein: Ar is aryl optionally substituted with one or more substituents independently selected from halogen, alkenyl, alkynyl, cyano, nitro, NHCOR4, COR4, NR5R6, NR5COR4, OR7, SR7, SOR10, SO 2 R10, NHSOR10, NHSO 2 R10, R8R9N—C 1 -C 6 alkyl, R8O—C 1 -C 6 alkyl, an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocyclyl and aryl, wherein: R4 is hydrogen, alkenyl, alkynyl, NR5R6, OR7, SR7, R8R9N—C 1 -C 6 alkyl, R8O—C 1 -C 6 alkyl, an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocyclyl or aryl; R5 and R6 are independently hydrogen, alkenyl, alkynyl, R8R9N—C 2 -C 6 alkyl, R80-C 2 -C 6 alkyl, an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocycly or or aryl, or R5 and R6, taken together with the nitrogen atom to which they are bonded, may form an optionally substituted heterocyclyl group; R7 is hydrogen, alkenyl, alkynyl, COR4, SOR10, SO 2 R10, R8R9N—C 2 -C 6 alkyl, R80-C 2 -C 6 alkyl, an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocyclyl or aryl, wherein R4 is as defined above; R8 and R9 are independently hydrogen, alkenyl, alkynyl, COR4, an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocyclyl or aryl, or R8 and R9, taken together with the nitrogen atom to which they are bonded, may form an optionally substituted heterocyclyl group, wherein R4 is as defined above; R10 is hydrogen, alkenyl, alkynyl, NR5R6, OR7, R8R9N—C 1 -C 6 alkyl, R8O—C 1 -C 6 alkyl, an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocyclyl or aryl, wherein R5, R6, R7, R8 and R9 are as defined above; R is an optionally further substituted straight or branched C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, heterocyclyl or aryl; R1, R2 and R3 are independently hydrogen, halogen, nitro, an optionally further substituted straight or branched C 1 -C 6 alkyl, NR5R6 or OR7, wherein R5, R6 and R7 are as defined above; and pharmaceutically acceptable salt thereof.