Patent ID: 7968119

Claim:
A composition for administration to a subject, the composition comprised of three components that have independent pharmaceutical potential and action to provide unobstructed narcotic analgesic action to a legitimate subject with moderate to severe pain, when taken as written and prescribed and absolutely no analgesic or euphoric potential and action once subjected to tampering and adulteration to liberate and isolate the narcotic component, wherein the composition consists of: (a) an immediate or time released narcotic agonist component; (b) a narcotic antagonist component comprising at least one antagonist, of comparable milligram and dosage potential of the agonist to negate any analgesic potential of the selected agonist, and to be sequestered and released, if and only if, the composition is subjected to tampering or adulteration; and (c) an immediate acting antagonist removal component from a group consisting of pharmaceutical agents, botanical agents, and mixtures thereof, to ensure the elimination of the sequestered antagonist component from the gastrointestinal tract of the subject, combined in a combination for oral administration in a formula creating a tamper-proof narcotic delivery system only when subjected to tampering and adulteration; wherein, the agonist having a narcotic effect is selected from and may be alfentanil, allylprodine, alphaprodine, anileridine, benzylmorphine, benzitramide, bupernorphine, butorphanol, clonitazcene, codeine, cyclazocine, desomorphine, dextromoramide, dexocine, diampromide, dihydrocodeine, dihydromorphine, dimenoxadol, dimepheptanol, dimethylthiambutene, dioxaphetyl butyrate, dipipanone, eptazocine, ethoheptazine, ethylmethylthiambutene, ethylmorphine, etonitazene, fentanyl, heroin, hydrocodone, hydromorphone, hydroxypethidine, isomethadone, ketobemidone, levallorphan, levorphanol, levophenacyl morphan, lofentanil, meperidine, meptazinol, metazocine, methadone, metopon, morphine, myrophine, nalbuphine, narceine, nicomorphine, norlevorphanol, normethadone, nalorphine, normorphine, norpipanone, opium, oxycodone, oxymorphone, papaveretum, pentazocine, phenadoxone, phenomorphan, phenazocine, phenoperidine, piminodine, piritramide, propheptazine, promedol, properidine, propiram, propoxyphene, sufentanil, tramadol, tilidine, salts thereof or mixtures thereof, wherein the antagonist component is selected from the narcotic antagonist group and consisting of naltrexone, nalmefene, and a mixture thereof, wherein the antagonist removal component methylnaltrexone.