Patent ID: 8080368

Claim:
A method for determining whether an agent can be used to reduce the growth of an ovarian tumor, comprising the steps of: a) providing a sample of ovarian tumor cells; b) exposing a portion of the sample of the ovarian tumor cells to a taxane compound, a platinum compound or a combination of agents consisting of a taxane compound and a platinum compound; c) determining the level of expression of two or more markers selected from the group consisting of a cohXres112c05 marker comprising the sequence of SEQ ID NO: 1, a jlhbab397f01 marker comprising the sequence of SEQ ID NO: 18, a jlhbab412e01 marker comprising the sequence of SEQ ID NO: 16, a jlhbab453e07 marker comprising the sequence of SEQ ID NO: 17 and a jlhbae334b03 marker comprising the sequence of SEQ ID NO:4 in the portion of the sample of ovarian tumor cells exposed to the compound or combination and in a portion of the sample of ovarian tumor cells not exposed to the compound or combination; and d) determining that the compound or combination can be used to reduce the growth of said tumor when the level of expression of one or more of said markers is increased in the portion of the sample of ovarian tumor cells exposed to the compound or combination relative to the level of expression of the one or more markers in the portion of the sample of ovarian tumor cells not exposed to the compound or combination.