Patent ID: 8067396

Claim:
A compound having a formula II(a): wherein R 1 and R 2 are the same or different and each represents a hydrogen atom, a lower alkyl group, a lower aliphatic acyl group, or a lower alkoxycarbonyl group; R 4 represents a C 1 -C 4 alkyl group; n represents an integer 2 or 3; X represents a group of the formula ═N-D, wherein D represents a hydrogen atom, a C 1 -C 6 alkyl group or a phenyl group; Y represents an ethylene group, an ethynylene group, a group of the formula —CO—CH 2 —, a group of a formula —CH(OH)—CH 2 —, an unsubstituted phenylene group, or a phenylene group substituted with from 1 to 3 substituents selected from the group consisting of a halogen atom and a lower alkyl group; Z represents an unsubstituted C 1 -C 6 alkylene group or a C 1 -C 6 alkylene group substituted with from 1 to 3 hydroxyl groups; R 5 represents an unsubstituted C 3 -C 10 cycloalkyl group, an unsubstituted C 6 -C 10 aryl group, or a C 3 -C 10 cycloalkyl or C 6 -C 10 aryl group substituted with from 1 to 3 substituents selected, from the group consisting of a halogen atom, a lower alkyl group, a halogeno lower alkyl group, a lower alkoxy group and a lower alkylthio group; R 6 and R 7 each represents a hydrogen atom, a halogen atom, a lower alkyl group, a halogeno lower alkyl group, a lower alkoxy group or a lower alkylthio group; R 10 and R 11 are the same or different and each represents a hydrogen atom or a lower alkyl group; or a pharmacologically acceptable salt thereof.