Patent ID: 7718162

Claim:
A medicinal aerosol composition comprising: a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, and a mixture thereof; an excipient comprising a compound of the structure R 1 —(O—CH 2 —CH 2 ) n —X; wherein X is selected from the group consisting of: —C(O)OH; —S(O 2 )OH; —OS(O 2 )OH; —P(OH) 2 O; —OP(OH) 2 O; —N(R 2 )(R 2 ); —OC(R 2 )(R 2 )—C(O)—Z; —OC(O)—R 2 —C(O)—Z; —O—R 3 —C(O)—Z; and —OC(O)CH(R 3 )—N(R 2 )(R 2 ); Z is selected from —OH; —N(R 2 )(R 2 ); —NH—R 2 —NH—; an amino acid residue; a peptide residue with from 2 to 8 amino acids; or a hydroxy acid; n is from 1 to 250; R 1 is methyl or ethyl; Each R 2 is independently selected from hydrogen or linear, branched, or cyclic hydrocarbon with 1 to 6 carbons; and R 3 is independently selected from hydrogen or linear, branched, or cyclic hydrocarbon with 1 to 6 carbons, wherein R 2 and R 3 may optionally be connected together to form an alkylene bridge of from 2 to 4 carbons; and a drug.