Patent ID: 7910100

Claim:
An isolated antibody, antibody fragment or derivative thereof comprising light chain variable (V L ) region complimentarity determining regions 1, 2, and 3 (CDR1, CDR2, and CDR3), and heavy chain variable (V H ) region CDR1, CDR2, and CDR3, the CDRs being present in each of said variable chains in CDR1, CDR2, CDR3 order and having the amino acid sequences of SEQ ID NOs: 166, 167, 168, 169, 170, and 171, respectively, wherein the antibody, antibody fragment or derivative thereof specifically binds to at least one epitope of the extracellular or intracellular domain of the mammalian ether-a-go-go 1 (EAG1) ion channel and does not bind to the mammalian EAG2 channel.