Patent ID: 7273624

Claim:
A process for producing a stable dosage form for oral administration, consisting essentially of: a.) providing a powdered or granulated premix comprising: (i) 5 to 35% by weight of at least one ubiquinone; (ii) 30 to 90% by weight of at least one melt-processable matrix-forming excipient selected from at least one of synthetic polymers, modified natural polymers, natural or predominantly natural polymers and sugar alcohols; (iii) 2 to 25% by weight of at least one surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.; and optionally, (iv) other pharmaceutical excipients, b.) melting the premix, without addition of solvent, in a kneader or a screw-type extruder to obtain a homogeneous melt, and, c.) shaping and solidifying the melt to obtain a solid dispersion product.