Patent ID: 8106184

Claim:
A method of making a compound having Formula I: wherein R 1 is alkyloxy or substituted alkyloxy, comprising: i) mixing a) tetra-acyl or substituted acyl ribofuranose and b) a compound having formula II: wherein R 2 is alkyloxy, substituted alkyloxy, aryloxy, substituted aryloxy, alkylthiol, substituted alkylthiol, arylthiol, substituted arylthiol, aminooxy, substituted aminooxy, N-alkylaminooxy or substituted N-alkylaminooxy, and wherein R 1 and R 2 are not the same; under conditions such that a compound of formula III: wherein R 3 , R 4 , and R 5 are the same or different and, at each occurrence, independently acyl or substituted acyl, is formed; and ii) subjecting the compound of formula III to conditions such that a compound of formula I is formed.