Patent ID: 7754861

Claim:
A method for purifying a target protein group comprising the steps of: (a) contacting a sample comprising at least 95% of the target protein group and at most 5% of contaminating proteins with a library comprising at least 100 different binding moieties in an amount sufficient to bind a majority of the contaminating proteins and a minority of the target protein group, but not a majority of the target protein group; (b) binding the majority of the contaminating proteins and the minority of the target protein group, but not the majority of the target protein group, to the library of binding moieties; (c) separating the unbound majority of the target protein group from the majority of the contaminating proteins and the minority of the target protein group bound to the library of binding moieties; and (d) collecting the unbound majority of the target protein group which is more pure than the target protein group in the sample.