Patent ID: 8835631

Claim:
A piperazine compound represented by formula <3> wherein R 1 and R 2 are the same or different and each is hydrogen, halogen, lower alkyl, lower alkoxy, amino, nitro, hydroxy, cyano or amino which is mono- or di-substituted by at least one functional group selected from the group consisting of lower alkyl and lower acyl, R 3 , R 4 and R 5 are the same or different and each is hydrogen, halogen, lower alkyl, lower alkoxy, nitro, amino, hydroxy, cyano or amino which is mono- or di-substituted by at least one functional group selected from the group consisting of lower alkyl and lower acyl, R 6 and R 7 are the same or different and each is hydrogen, lower alkyl, lower alkyl substituted by 1 to 3 halogens, aralkyl, acyl or lower acyl substituted by 1 to 3 halogens, R 8 and R 9 are the same or different and each is hydrogen or lower alkyl, any two of R 1a -R 1d are bonded to each other to form alkylene having a carbon number of 1-2, and other substituents are the same or different and each is hydrogen, lower alkyl, aralkyl or hydroxy lower alkyl, Y is a group represented by formula wherein R 10 and R 11 are the same or different and each is hydrogen or lower alkyl, R 12 and R 13 are the same or different and each is hydrogen or lower alkyl, or R 12 and R 13 are groups that form alkylene in combination, R 14 and R 15 are the same or different and each is hydrogen or lower alkyl, m is an integer of 0-2, n is an integer of 0-2, and 0≦m+n≦2, and ring A is pyrimidyl, or a pharmaceutically acceptable salt thereof.