Patent ID: 7498347

Claim:
A compound of formula (I) a stereochemically isomeric form thereof an N-oxide form thereof or a pharmaceutically acceptable acid or base addition salt thereof, wherein —R 1 —R 2 — is a bivalent radical of formula —O—CH 2 —O— (a-1), —O—CH 2 —CH 2 — (a-2), —O—CH 2 —CH 2 —O— (a-3), —O—CH 2 —CH 2 —CH 2 — (a-4), —O—CH 2 —CH 2 —CH 2 —O— (a-5), —O—CH 2 —CH 2 —CH 2 —CH 2 — (a-6), —O—CH 2 —CH 2 —CH 2 —CH 2 —O— (a-7), —O—CH 2 —CH 2 —CH 2 —CH 2 —CH 2 — (a-8), wherein in said bivalent radicals optionally one or two hydrogen atoms on the same or a different carbon atom may be replaced by C 1-6 alkyl or hydroxy, R 3 is hydrogen, halo, C 1-6 alkyl or C 1-6 alkyloxy; R 4 is hydrogen, halo, C 1-6 alkyl; C 1-6 alkyl substituted with cyano, or C 1-6 alkyloxy; C 1-6 alkyloxy; cyano; amino or mono or di(C 1-6 alkyl)amino; R 5 is hydrogen or C 1-6 alkyl, and the —OR 5 radical is situated at the 3- or 4-position of the piperidine moiety; L is a radical of formula -Alk-R 6 (b-1), -Alk-X—R 7 (b-2), -Alk-Y—C(═O)—R 9 (b-3), wherein each Alk is C 1-2 alkanediyl; and R 6 is aryl; R 7 is aryl; X is O, S, SO 2 or NR 8 ; said R 8 being hydrogen or C 1-6 alkyl; R 9 is aryl; Y is a direct bond, O, S, or NR 10 wherein R 10 is hydrogen or C 1-6 alkyl; and aryl represents phenyl substituted with 1, 2 or 3 hydroxycarbonyl.