Patent ID: 8535688

Claim:
A vaccine comprising an immunogenic component wherein the immunogenic component comprises an isolated or synthetic lipopolysaccharide (LPS) inner core of a galE mutant of immunotype L3 of Neisseria meningitides , wherein the LPS inner core consists of the structure: and comprises an LPS inner core epitope of the immunotype L3, but not of immunotype L4 of Neisseria meningitides , wherein the phosphoethanolamine (PEtn) group is linked to the position 3 of the HepII moiety of the LPS inner core and wherein the LPS inner core is specifically recognized by the monoclonal antibody B5 produced by the hybridoma deposited with the accession number IDAC 260900-1, wherein the vaccine when administered to a recipient subject, elicits an antibody that recognizes inner core LPS of Neisseria gonorrhoeae , Neisseria lactamica , and pathogenic strains of Neisseria meningitidis of immunotypes L3, L1, L7, L8, L9, L10, L11 and L12 and serogroups A, B, C, W, X, Y and Z of Neisseria meningitides.