Patent ID: 8071603

Claim:
A compound of formula (Ib): wherein: x and y are each 1; V is â€”C(O)â€” or â€”C(S)â€”; W is R 2 â€”N(R 1 )C(O)â€”; R 1 is selected from the group consisting of hydrogen, C 1 -C 12 alkyl, C 2 -C 12 hydroxyalkyl, C 4 -C 12 cycloalkylalkyl and C 7 -C 19 aralkyl; R 2 is selected from the group consisting of C 2 -C 12 alkenyl, C 2 -C 12 hydroxyalkenyl, C 2 -C 12 alkoxyalkyl, C 3 -C 12 cycloalkyl, C 4 -C 12 cycloalkylalkyl and unsubstituted C 7 -C 19 aralkyl; R 3 is phenyl substituted by C 1 -C 6 trihaloalkyl and optionally substituted by one or more substituents selected from the group consisting of halo, C 1 -C 6 alkyl, C 1 -C 6 trihaloalkyl and C 1 -C 6 trihaloalkoxy; R 4 is hydrogen, fluoro, chloro, C 1 -C 12 alkyl, C 1 -C 12 alkoxy, haloalkyl, cyano, nitro or â€”N(R 9 ) 2 ; R 5 , R 5a , R 6 , R 6a , R 7 , R 7a , R 8 and R 8a are each independently selected from hydrogen or C 1 -C 3 alkyl; and each R 9 is independently selected from hydrogen or C 1 -C 6 alkyl; as a stereoisomer, enantiomer or tautomer thereof or as a mixture of stereoisomers; or a pharmaceutically acceptable salt thereof.