Patent ID: 7550602

Claim:
A compound of the general formula VIII or IX: wherein: R 1 is a bond or a linker unit with from one to six atoms joined one to the other by bonds and forming a chain selected from the group consisting of carbon (C), oxygen (O) and nitrogen (N) and a ring group including at least one substituted or unsubstituted aromatic ring, including carbocyclic or heterocyclic aromatic rings, bicylic ring groups, and bridged ring groups wherein at least one ring is an aromatic ring, and fused ring groups other than 6,6-membered fused ring structures wherein at least one ring is an aromatic ring; R 2 is hydrogen (H) or a C 1 to C 6 aliphatic linear or branched chain; R 3 is a natural or unnatural L- or D-amino acid with a carbocyclic aromatic group-containing side chain, a natural or unnatural L- or D-amino acid with a carbocyclic aromatic group-containing side chain and an amine capping group, or is -R 6 -R 7 ; R 6 is a D-isomer of Phe, Phe(4-F), Phe(4-Br), Phe(4-CF 3 ), Phe(4-Cl), Phe(3-Cl), Phe(2-Cl), Phe(2,4-diCl), Phe(2,4-diF), Phe(3,4-diCl), Phe(5-Cl), Phe(2-Cl,4-Me), Phe(2-Me,4-Cl), Phe(2-F,4-Cl), Phe(4-I), Phe(2,4-diMe), Phe(2-Cl,4-CF 3 ), Phe(3,4-diF), Phe(4-I), Phe(3,4-di-OMe), Phe(4-Me), Phe(4-OMe), Phe(4-NC), or Phe(4-NO 2 ); R 7 is -R 8 , -R 9 or -R 8 -R 9 ; R 8 is between one and three natural or unnatural L- or D-amino acids; R 9 is an amine capping group; X is (CH 2 ) n , CH, NH, N, O, C═O, C═S, S, S═O or SO 2 ; and n is 0, 1, 2 or 3.