Patent ID: 7083807

Claim:
A pharmaceutical composition which can be administered orally, allowing the controlled release of at least one active substance, comprising: a) said at least one active substance, b) between 5% and 60% by weight, relative to the total weight of the composition, of at least one excipient, selected from the group consisting of inert matrices, hydrophilic matrices, lipid matrices, mixtures of inert matrices and of lipid matrices, mixtures of hydrophilic matrices and of inert matrices, with the exception of mixtures comprising a polyacrylic acid and at least one hydrophilic cellulose matrix; c) between 9.2% and 14.3% by weight, relative to the total weight of the composition, of at least one alkalinizing agent soluble in an aqueous phase under physiological pH conditions, selected from alkali or alkaline-earth metal hydroxides, carbonates, bicarbonates, phosphates, sodium borate and basic salts of organic acids.