Patent ID: 7985770

Claim:
A pharmaceutical composition comprising a (i) a bi-cyclic compound represented by the formula (I): wherein, A is —CH 2 OH, —COCH 2 OH, —COOH or a functional derivative thereof, X 1 and X 2 are hydrogen, lower alkyl or halogen; V 1 and V 2 are carbon or oxygen; W 1 and W 2 are wherein R 4 and R 5 are hydrogen, hydroxy, halogen, lower alkyl, lower alkoxy or hydroxy (lower) alkyl with the proviso that R 4 and R 5 are not hydroxy or lower alkoxy at the same time; Z is a carbon, oxygen, sulfur or nitrogen; R 1 is a saturated or unsaturated bivalent lower-medium aliphatic hydrocarbon residue which is unsubstituted or substituted with halogen, lower alkyl, hydroxy, oxo, aryl or heterocyclic group; R 2 is a saturated or unsaturated, lower or medium aliphatic hydrocarbon residue which is unsubstituted or substituted with halogen, oxo, hydroxy, lower alkyl, lower alkoxy, lower alkanoyloxy, lower cycloalkyl, lower cycloalkyloxy, aryl, aryloxy, heterocyclic group or heterocyclicoxy group; lower cycloalkyl; lower cycloalkyloxy; aryl, aryloxy, heterocyclic group or heterocyclicoxy group; R 3 is a hydrogen, a lower alkyl, lower cycloalkyl, aryl or heterocyclic group, and (ii) a fatty acid ester which is an ester of a fatty acid and an alcohol selected from the group consisting of propylene glycol, polyethylene glycol and a C1-6 monovalent alcohol.