Patent ID: 7622467

Claim:
A compound of formula (I): wherein: R 1 and R 2 taken together are selected from —NHC(═O)CH═CH—, —CH═CHC(═O)NH—, —NHC(═O)S—, and —SC(═O)NH—; R 3 is hydroxy and R 4 is hydrogen; one of R 5 and R 6 is —[X—C 1-6 alkylenyl] n —NR 10 R 11 or C 1-6 alkylenyl-NR 12 R 13 , and the other of R 5 and R 6 is selected from hydrogen, hydroxy, C 1-4 alkoxy, and C 1-4 alkyl, wherein C 1-4 alkyl is optionally substituted with halo, wherein each X is independently selected from —O—, —NH—, —S—, —NHSO 2 —, —SO 2 NH—, —NHC(═O)—, and —C(═O)NH—; each of R 10 , R 11 , R 12 , and R 13 is independently hydrogen or C 1-4 alkyl; or R 10 and R 11 , together with the nitrogen atom to which they are attached, or R 10 , together with the nitrogen atom to which it is attached and a carbon atom of the adjacent C 1-6 alkylenyl, or R 12 and R 13 , together with the nitrogen atom to which they are attached, or R 12 , together with the nitrogen atom to which it is attached and a carbon atom of the adjacent C 1-6 alkylenyl, form a heterocyclic or heteroaryl ring having from 5 to 7 ring atoms, and optionally containing an additional heteroatom selected from oxygen, nitrogen, and sulfur, wherein nitrogen is optionally substituted with —S(O) 2 —C 1-4 alkyl; and n is 1,2, or 3; and each of R 7 , R 8 , and R 9 is independently hydrogen or C 1-6 alkyl; or a pharmaceutically-acceptable salt or solvate or stereoisomer thereof.