Patent ID: 6849641

Claim:
An azaindole compound having the following chemical structure: wherein, A is selected from the group consisting of nitrogen, oxygen and sulfur and it is understood that when A is oxygen or sulfur, R 3 does not exist and there is no bond; B, D, E, F and G are independently selected from the group consisting of carbon and nitrogen wherein only one of D, E, F and G is nitrogen and the other of D, E, F, and G are carbon, and it is understood that when B, D, E, F or G is nitrogen, R 6 , R 7 , R 8 , R 9 and R 10 , respectively, do not exist and there is no bond; Z is selected from the group consisting of oxygen, sulfur and NR 11 wherein, R 11 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, hydroxy, alkoxy, aryloxy, —C(═O)-R″, —C(═O)O—R″, R″C(═O)O—, —S(═O) 2 R″, —C(═O)NR 12 R 13 , R 12 R 13 NC(═NH)—, and trihalomethanesulfonyl; R 1 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, heteroaryl, heteroalicyclic, hydroxy, alkoxy, trihalomethanecarbonyl, trihalomethanesulfonyl, —C(═O)O—R″, R″C(═O)O—, —S(═O) 2 R″, —C(═O)NR 12 R 13 , and R 12 R 13 NC(═NH)—; R 2 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl and halogen; when A is nitrogen, R 3 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, hydroxy, alkoxy, aryloxy, —C(═O)-R″, —C(═O)O—R″, trihalomethanesulfonyl, R″C(═O)O—, —S(═O) 2 R″, —C(═O)NR 12 R 13 , and R 12 R 13 NC(═NH)—; R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and R 10 are independently selected from the group consisting of hydrogen, alkyl, trihaloalkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, heteroalicyclic, hydroxy, alkoxy, aryloxy, thiohydroxy, thioalkoxy, —R 12 NC (═NH)NR 13 R 14 , thioaryloxy, —S(═O)R″, —S(═O)NR 12 R 13 , R 12 S(═O) 2 NR 13 —, trihalomethanesulfonyl, —C(═O)-R″, —C(═O)O—R″, R″C(═O)O—, —S(═O) 2 R″, —C(═O) NR 12 R 13 , cyano, nitro, halo, amino —OC(═O)NR 12 R 13 , R 12 OC(═O)NR 13 —, —OC(═S)NR 12 R 13 , R 12 OC(═S)NR 13 —, R 12 R 13 NC(═NH)—, —NR 12 C(═O)NR 13 R 14 , R 12 C(═O)NR 13 —, and —NR 12 R 13 ; wherein R″ is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, heteroaryl (bonded through a ring carbon) and heteroalicyclic (bonded through a ring carbon); and wherein R 12 , R 13 , and R 14 are independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, —C(═O)—R″, —S(═O) 2 R″, and combined, a five or six membered heteroalicyclic ring containing at least one nitrogen; and the physiologically acceptable salts thereof.