Patent ID: 8182987

Claim:
A method for performing phase identification of a cell cycle, the method comprising the steps of: visualizing, by respectively using markers, at least two or more gene-expression products whose amounts in a cell change in a cell-cycle dependent manner; and detecting the markers to distinguish a proliferation phase of the cycle from a resting phase of the cycle, wherein the at least two or more gene-expression products are co-expressed in a cell and comprise (i) a first gene-expression product comprising a partial fragment of Cdt1; wherein the partial fragment of Cdt1 excludes a Geminin binding site, and increases in a G1 phase and decreases in an S/G2/M phase; and (ii) a second gene-expression product comprising a partial fragment of Geminin; wherein the partial fragment of Geminin excludes a Cdt1 binding site, and decreases in the G1 phase and increases in the S/G2/M phase; wherein the first gene-expression product and the second-gene expression product are labeled by the markers, and the markers are different from each other, to visualize the first gene-expression product and the second gene-expression product.