Patent ID: 7268117

Claim:
A method of assessing whether a patient is afflicted with endometriosis, the method comprising comparing: a) the abundance of one or more marker polypeptides selected from the group consisting of: fibrinogen α-chain (SEQ ID NO:1), or a fragment thereof; fibrinogen β-chain (SEQ ID NO:2), or a fragment thereof; ADSGEGDFLAEGGGVR (fibrinopeptide A) (SEQ ID NO:3), or a fragment thereof; GEGDFLAEGGGVR AD(dehydroA) (SEQ ID NO:4), or a fragment thereof; DSGEGDFLAEGGGVR (SEQ ID NO:5), or a fragment thereof; DSGEGDFLAEGGGV (SEQ ID NO:6), or a fragment thereof; SGEGDFLAEGGGVR (SEQ ID NO:7), or a fragment thereof; SGEGDFLAEGGGV (SEQ ID NO:8), or a fragment thereof; GEGDFLAEGGGVR (SEQ ID NO:9), or a fragment thereof; GEGDFLAEGGGV (SEQ ID NO:10), or a fragment thereof; EGDFLAEGGGVR (SEQ ID NO:11), or a fragment thereof; EGDFLAEGGGV (SEQ ID NO:12), or a fragment thereof; GDFLAEGGGVR (SEQ ID NO:13), or a fragment thereof; GDFLAEGGGV (SEQ ID NO:14), or a fragment thereof; DFLAEGGGVR (SEQ ID NO:15), or a fragment thereof; DFLAEGGGV (SEQ ID NO:16), or a fragment thereof; FLAEGGGVR (SEQ ID NO: 17), or a fragment thereof; FLAEGGGV (SEQ ID NO: 18), or a fragment thereof; LAEGGGV (SEQ ID NO: 19), or a fragment thereof; AEGGGV (SEQ ID NO:20), or a fragment thereof; EGGGV (SEQ ID NO:21), or a fragment thereof; ADS*GEGDFLAEGGGVR (phosphorylated fibrinopeptide A) (SEQ ID NO:22), or a fragment thereof; DS*GEGDFLAEGGGVR (SEQ ID NO:23), or a fragment thereof; DS*GEGDFLAEGGGV (SEQ ID NO:24), or a fragment thereof; S*GEGDFLAEGGGVR (SEQ ID NO:25), or a fragment thereof; S*GEGDFLAEGGGV (SEQ ID NO:26), or a fragment thereof; QGVNDNEEGFFSAR (fibrinopeptide B) (SEQ ID NO:27), or a fragment thereof; pyr-EGVNDNEEGFFSA (SEQ ID NO:28), or a fragment thereof; DEAGSEADHEGTHST (SEQ ID NO:29), or a fragment thereof; SVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCN YITELRRQHARASHLGLAR (C3a) (SEQ ID NO:31), or a fragment thereof; C3b (SEQ ID NO:32), or a fragment thereof; SSKITHRIHWESASLLR (SEQ ID NO:36), or a fragment thereof; and HWESASLL (SEQ ID NO:37), or a fragment thereof, in a patient sample, wherein the fragment thereof consists of 7–15 consecutive amino acid residues of the marker polypeptide, and b) the normal abundance of the one or more of marker polypeptides in a sample from a control subject not afflicted with endometriosis, wherein a significantly greater abundance of one or more of said marker polypeptides in the patient sample as compared to the normal abundance of one or more of said marker polypeptides indicates that the patient is afflicted with endometriosis.