Patent ID: 8337853

Claim:
A monoclonal antibody or antigen-binding fragment thereof that binds dengue type 4 virus, comprising: a heavy chain CDR1 polypeptide having the amino acid sequence of SEQ ID NO: 99, a heavy chain CDR2 polypeptide having the amino acid sequence of SEQ ID NO: 101, and a heavy chain CDR3 polypeptide having the amino acid sequence of SEQ ID NO: 103; and a light chain CDR1 polypeptide having the amino acid sequence of SEQ ID NO:107, a light chain CDR2 polypeptide having the amino acid sequence of SEQ ID NO: 109, and a light chain CDR3 polypeptide having the amino acid sequence of SEQ ID NO: 111; or a heavy chain CDR1 polypeptide having the amino acid sequence of SEQ ID NO: 131, a heavy chain CDR2 polypeptide having the amino acid sequence of SEQ ID NO: 133, and a heavy chain CDR3 polypeptide having the amino acid sequence of SEQ ID NO: 135; and a light chain CDR1 polypeptide having the amino acid sequence of SEQ ID NO:139, a light chain CDR2 polypeptide having the amino acid sequence of SEQ ID NO: 141, and a light chain CDR3 polypeptide having the amino acid sequence of SEQ ID NO: 143.