Patent ID: 7662910

Claim:
A compound having a formula: wherein R 1 is a substituted or unsubstituted cycloalkyl or substituted or unsubstituted aryl; P 1 is a primary pharmacophore selected from the group consisting of —C(O)O—, —NHC(NH)NH—, —NHC(NH)CH 2 —, —CH 2 C(NH)NH—, —NHC(NH)—, —C(NH)NH—, —NHC(O)NH—, —OC(O)NH—, —NHC(O)O—, —NHC(S)NH—, —CH 2 C(O)NH—, —NHC(O)CH 2 —, —C(O)NH—, —NHC(O)—, and P 2 is a secondary pharmacophore selected from the group consisting of —NH—, —C(O)—, —CH(OH)—, —O(CH 2 CH 2 O)q—, —C(O)O——OC(O)—, —NHC(NH)NH—, —NHC(NH)CH 2 —, —CH 2 C(NH)NH—, —NHC(O)NH—, —OC(O)NH—, —NHC(O)O—, —C(O)NH—, —NHC(O)— and —NHC(S)NH—; P 3 is a tertiary pharmacophore selected from the group consisting of substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclyl, —O(CH 2 CH 2 O) q R 2 , OR 2 , —C(O)NHR 2 , —C(O)NHS(O) 2 R 2 , —NHS(O) 2 R 2 , —OC 2 -C 4 alkyl-C(O)OR 2 , —C(O)R 2 , —C(O)OR 2 and carboxylic acid analogs, wherein R 2 is a member selected from the group consisting of hydrogen, substituted or unsubstituted C 1 -C 4 alkyl, substituted or unsubstituted C 3 -C 8 cycloalkyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl and substituted or unsubstituted aryl C 1 -C 4 alkyl; the subscript q is 0 to 6; the subscript m is 0 or 1; and L 1 is a substituted or unsubstituted C 3 -C 6 cycloalkylene; L 2 is a linker selected from the group consisting of substituted or unsubstituted C 1 -C 12 alkylene, substituted or unsubstituted C 3 -C 6 cycloalkylene, substituted or unsubstituted arylene, substituted or unsubstituted heteroarylene; an amino acid, a dipeptide and a dipeptide analog; and combinations thereof, such that when P 2 is —C(O)O— or —O(CH 2 CH 2 O) q — and L 2 is unsubstituted C 1 -C 12 alkylene, then m=1, P 3 is selected from the group consisting of substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclyl, —O(CH 2 CH 2 O) q R 2 , OR 2 , —C(O)NHR 2 , —C(O)NHS(O) 2 R 2 , —NHS(O) 2 R 2 , —OC 2 -C 4 alkyl-C(O)OR 2 , —C(O)R 2 and carboxylic acid analogs, and R 2 of —O(CH 2 CH 2 O) q R 2 is selected from the group consisting of hydrogen, substituted C 1 -C 4 alkyl, substituted or unsubstituted C 3 -C 8 cycloalkyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl and substituted or unsubstituted aryl C 1 -C 4 alkyl.