Patent ID: 7400931

Claim:
A device for use in a body having a blood conduit, the device comprising: a first electrical output channel configured to deliver intermittent pulses having a sub-threshold voltage below a threshold voltage required to cause a local depolarization of cardiac myocyte cell membranes; a first lead comprising a proximal end configured to be electrically connected to the first electrical output channel, and a distal end adapted to be placed in the blood conduit; a cannula including a lumen configured to deliver a liquid or solid treatment agent to the distal end of the first lead, the liquid or solid treatment agent stimulating angiogenesis, wherein the first lead includes at least a portion disposed within the lumen and has an outer diameter that is smaller than an inner diameter of the cannula to form an annular space suitable for flow of the liquid or solid treatment agent; and at least one electrode electrically connected to the first electrical output channel and disposed near the distal end of the first lead, the at least one electrode configured to deliver the sub-threshold voltage and one or more of pacing and defibrillation voltages, wherein the first electrical output channel, the first lead, and the cannula are configured to be implanted in the body.