Patent ID: 7799828

Claim:
A method for treating a condition selected from osteoporosis, obesity, breast cancer, depression, vaginal dryness, rheumatoid arthritis, vasomotor symptoms, and urogenital or vulvar vaginal atrophy in an mammal in need thereof, said method comprising administering to the mammal a therapeutically effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof wherein each R 2 is independently selected from OH, alkyl, or halogen; q is independently selected from 0, 1, or 2; X is —(CH 2 ) n — where n is 0, 1, 2, or 3, —C(R g ) 2 —, or —O—; each of R 6 and R 7 are selected from H or alkyl; R 8 is —CO 2 H, —(R h ) t CO 2 H, or —CONR a R b ; t is 1 to 8; R a is H, alkyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl; R b is H, alkyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl; or R a and R b may combine with the atoms to which they are bound to form a heteroaryl or heterocyclyl ring; R g is alkyl; and each R h independently is —CR j R k —, where each of R j and R k independently are selected from H and alkyl.