Patent ID: 7534800

Claim:
A compound of formula (I): wherein: R stands for phenyl or naphthyl, wherein each substitutable carbon atom in R, is optionally and independently substituted by one or more of halogen, or NR 2 R 2 , wherein each R 2 may be the same or different and is as defined below; R 2 is hydrogen, or C 1-12 alkyl; R′ is C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, carbocyclyl, indole or benzo[d][1,3]dioxole, each of which is optionally substituted, wherein: the optionally substituted carbocyclyl or heterocyclyl group is optionally fused to one to three unsaturated, partially unsaturated or frilly saturated five to seven membered rings containing zero to three heteroatoms, each substitutable carbon atom in R′, including the optional fused ring, is optionally and independently substituted by one or more of C 1-12 alkyl, C 3-12 heterocycloalkyl, halogen, haloalkyl, OR 2 , wherein each R 2 may be the same or different and is as defined above; R″ is hydrogen, or C 1-12 alkyl; X is NR 5 ; and R 5 is H, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 haloalkyl or C 1-4 haloalkyl; and Y is absent or is NR 6 , CR 6 R 6 , or C 1-4 alkylene wherein each R 6 may be the same or different and is H, or C 1-4 alkyl; and Z is O; or a pharmaceutically acceptable salt or prodrug thereof.