Patent ID: 7781421

Claim:
A steroid or D-homosteroid of Formula (A) wherein R 2 is selected from the group consisting of hydrogen, alkoxy, and substituted or unsubstituted morpholine R 3a is hydroxyl or carboxyl; R 3b is hydrogen, alkyl, alkenyl, or alkynyl optionally substituted with halo, hydroxyl, or substituted or unsubstituted aryl; R 5 is α- or β-hydrogen; R 10 is hydrogen or C 1-4 alkyl; R 15 is hydrogen or oxo; R 6 , R 11 and R 12 are independently hydrogen or oxo; L 3a is selected from the group consisting of a bond, C 1-3 alkyl, heterosubstituted C 1-3 alkyl, or alkoxy; X 4 -X 5 -X 6 is selected from the group consisting of X 9 -X 11 -X 12 is selected from the group consisting of X 40 is a bond or a carbon atom; and E is a 5- or 6-membered carbocyclic ring in the β-configuration in relation to the C and D rings, comprising a hydrogen bond acceptor and (i) the carbons at C(13) and C(17) when X 40 is a bond, or (ii) the carbons at C(13) and C(17a) when X 40 is carbon.