Patent ID: 8519158

Claim:
A compound of Formula II: wherein: R 1 is selected from among SR A , NO 2 , CN, CF 3 , COR A , CONR A R B , SOR A , and SO 2 R A ; R 2 is selected from among F, Cl, Br, I, SR A , NO 2 , CF 3 , COR A , CO 2 R A , CONR A R B , SOR A , SO 2 R A , SO 2 NR A R B , NHCOR A , and NHCONR A R B ; R 3 and R 4 each independently is selected from among hydrogen, F, Cl, OR A , an optionally substituted C 1 -C 4 alkyl, and CF 3 ; R 3 is selected from among hydrogen, F, Cl and CF 3 ; R 6a and R 7a each independently is selected from among hydrogen, an optionally substituted C 1 -C 6 alkyl, CF 3 , an optionally substituted C 1 -C 6 heteroalkyl, an optionally substituted C 2 -C 6 alkynyl, and an optionally substituted C 2 -C 6 alkenyl; R 9 is selected from an optionally substituted C 1 -C 8 alkyl, an optionally substituted C 2 -C 8 alkenyl, CF 3 , an optionally substituted C 2 -C 8 haloalkenyl, an optionally substituted C 2 -C 8 heteroalkenyl, an optionally substituted C 2 -C 8 alkynyl, an optionally substituted C 2 -C 8 haloalkynyl, an optionally substituted C 2 -C 8 heteroalkynyl, an optionally substituted heteroaryl, CH(R D )OR A , CH(R D )NR A R B , COR A , and (CH 2 ) m R C ; R 10 is selected from among hydrogen, an optionally substituted C 1 -C 6 alkyl, CF 3 , an optionally substituted C 1 -C 6 heteroalkyl, an optionally substituted C 2 -C 6 alkynyl, and an optionally substituted C 2 -C 6 alkenyl; R 12 and R 13 each independently is selected from among hydrogen, F, Cl, OR A , NR A R B , SR A , an optionally substituted C 1 -C 6 alkyl, CF 3 , an optionally substituted C 1 -C 6 heteroalkyl, an optionally substituted C 2 -C 6 alkynyl, an optionally substituted C 2 -C 6 alkenyl, and (CH 2 ) m R C ; R A is selected from among hydrogen, an optionally substituted C 1 -C 4 alkyl and CF 3 ; R B is selected from among hydrogen, an optionally substituted C 1 -C 4 alkyl, CF 3 , and an optionally substituted C 1 -C 4 heteroalkyl; R C is selected from among an optionally substituted aryl and an optionally substituted heteroaryl that is optionally substituted with a substituent selected from among F, Cl, Br, I, CN, OR A , NO 2 , NR A R B , SR A , SOR A , SO 2 R A , an optionally substituted C 1 -C 4 alkyl, CF 3 , and an optionally substituted C 1 -C 4 heteroalkyl; R D is selected from among hydrogen, an optionally substituted C 1 -C 4 alkyl, CF 3 , and an optionally substituted C 1 -C 4 heteroalkyl; Z is CR A R B ; n is 0; and m is 1 or 2; or a pharmaceutically acceptable salt thereof.