Patent ID: 7230106

Claim:
A process for preparing a compound, comprising the steps of: reacting a compound of Formula AI: with a compound of Formula II: thereby obtaining a compound of Formula AIII: wherein R 7 is selected from the group consisting of cyclopentyl, phenyl, pyrazolyl, isoxazolyl, imidazolyl, pyrrolyl, indolyl, isoquinolinyl, pyridinyl, tetrahydrothiophenyl, thienyl, furyl, tetrahydrofuranyl, pyrazinyl, pyrrolidinyl, and piperidinyl, wherein R 7 is unsubstituted or substituted with at least one substituent selected from the group consisting of halogen, alkoxy, nitro, and alkylamino; and reacting the compound of Formula AIII with a compound comprising X—R 1 , wherein X is selected from the group consisting of Cl, Br, and I, and wherein R 1 is selected from the group consisting of C 1-10 alkyl and aryl C 1-10 alkyl, wherein R 1 is unsubstituted or substituted with at least one substituent selected from the group consisting of halogen, alkoxy, alkylamino, dialkylamino, and keto, thereby obtaining a compound of Formula AIV: wherein the compound of Formula AIV is suitable for use as a macrophage migration inhibitory factor inhibitor.