Patent ID: 8080566

Claim:
A compound of Formula III or a pharmaceutically acceptable salt, ester, or prodrug thereof, wherein X is chosen from lower alkyl, lower alkenyl, and lower alkynyl, any of which may be optionally substituted with one or more substituents chosen from halogen, hydroxy, and cyano; R 1 is chosen from hydrogen, hydroxy, lower cycloalkyl, lower heterocycloalkyl, lower amino, thio, carboxy, amido, and acyl; W is chosen from C, N, and O; r is 0-3; each R 11 is individually chosen from hydrogen, halogen, hydroxy, lower hydroxyalkyl, lower alkyl, halogen, lower haloalkyl, lower alkoxy, lower haloalkoxy, monocyclic 5-membered heteroaryl, C(O)OR 12 , C(O)N(R 12 )(R 13 ), perfluoromethyl, and perfluoromethoxy; R 12 and R 13 are individually chosen from hydrogen, lower alkyl, lower cycloalkyl, lower cycloalkylalkyl, lower heterocycloalkyl, lower heterocycloalkylalkyl, lower heteroaryl, lower heteroarylalkyl, any of which may be optionally substituted with one or more substituents chosen from halogen, hydroxy, cyano, lower alkyl, lower alkenyl, lower alkynyl, lower heteroalkyl, lower alkoxy, lower haloalkyl, and lower haloalkoxy; and R 14 is an unsubstituted five-membered monocyclic heteroaryl.