Patent ID: 8552019

Claim:
A compound of the Formula A: wherein: n is 0, 1, 2, 3, 4 or 5; W is C, Y is N, Z is C; X is O, CH 2 or NH; Ring K is aryl or heteroaryl; L 1 is C 0 -C 6 alkyl, C 2 -C 6 alkenyl or heteroaryl, wherein said alkyl is optionally substituted with C 1 -C 6 alkyl or phenyl, wherein said phenyl is optionally substituted with C 1 -C 6 alkyl, C 1 -C 6 alkyl-OH, O(C 1 -C 6 )alkyl, halo and OH; L 2 is C 0 -C 6 alkyl, C 2 -C 6 alkenyl or heteroaryl, wherein said alkyl is optionally substituted with C 1 -C 6 alkyl or phenyl; R 1 is heterocyclyl which is optionally substituted with C 1 -C 6 alkyl, C 1 -C 6 alkyl-OH, O(C 1 -C 6 )alkyl, NH(C═O)C 1 -C 6 alkyl, C 2 -C 6 alkenyl, CO 2 H, halo, OH, oxo and NR 8 R 9 ; R 2 is independently selected from: H, C 1 -C 6 alkyl, C 1 -C 6 alkyl-OH, O(C 1 -C 6 )alkyl, C 2 -C 6 alkenyl, CO 2 H, halo, OH and NR 8 R 9 ; R 3 is selected from: H, C 1 -C 6 alkyl, C 1 -C 6 alkyl, O(C 1 -C 6 )alkyl, C 2 -C 6 alkenyl, CO 2 H, halo, OH and NR 8 R 9 when W is C; R 5 is selected from: H, C 1 -C 6 alkyl, C 1 -C 6 alkyl-OH, O(C 1 -C 6 )alkyl, C 2 -C 6 alkenyl, CO 2 H, halo, OH and NR 8 R 9 ; R 6 and R 7 are independently selected from: H and C 1 -C 6 alkyl; and R 8 and R 9 are independently selected from: H and C 1 -C 6 alkyl; or a pharmaceutically acceptable salt or a stereoisomer thereof.