Patent ID: 8410430

Claim:
A method of mass spectrometry comprising: providing a Time of Flight mass analyser comprising an orthogonal acceleration electrode and a drift or time of flight region; repeatedly energising said orthogonal acceleration electrode so as to repeatedly orthogonally accelerate packets of ions into said drift or time of flight region, wherein the periodicity of energising said orthogonal acceleration electrode or the time period between successive energisations of said orthogonal acceleration electrode is less than the time of flight of ions having the maximum mass to charge ratio within said packets of ions which are orthogonally accelerated into said drift or time of flight region; orthogonally accelerating packets of ions into said drift or time of flight region with a first periodicity or wherein a first time period Δt 1 is maintained between successive energisations of said orthogonal acceleration electrode; and obtaining first time of flight or mass spectral data; orthogonally accelerating packets of ions into said drift or time of flight region with a second periodicity or wherein a second different time period Δt 2 is maintained between successive energisations of said orthogonal acceleration electrode; and obtaining second time of flight or mass spectral data; comparing said first time of flight or mass spectral data with said second time of flight or mass spectral data; and identifying as non-wrapped data, time of flight or mass spectral peaks which have substantially the same time of flight, mass or mass to charge ratio and/or substantially the same intensity in said first time of flight or mass spectral data as in said second time of flight or mass spectral data.