Patent ID: 7947685

Claim:
A compound of formula (I) wherein R 1 is a 5-ring selected from the group consisting of formulae (IIa), (IIb), (IIc), (IId), (IIe), (IIf), and (IIg): R 2 is H, C 3 -C 6 -cycloalkyl, or —(CH 2 ) m —R a ; R 3 is aryl, or heteroaryl each of which is optionally substituted by: CN, Cl, F, Br, CF 3 , CHF 2 , —O—C 1 -C 7 -alkyl, —(CO)—R b , —(CH 2 ) m —R c , —NH—(CO)—C 1 -C 7 -alkyl, —O—CH 2 F, —O—CHF 2 , —O—CF 3 , —S(O) 2 —R d , or heteroaryl which is optionally substituted by C 1 -C 7 -alkyl; R 4 is H, —OH, Cl, F, Br, CN, —CHF 2 , CF 3 , C 1 -C 7 -alkyl, —O—(CO)—C 1 -C 7 -alkyl, or —(CH 2 ) m —R e ; R 5 is C 1 -C 7 -alkyl, C 1 -C 7 -alkylC 3 -C 6 -cycloalkyl, —(CH 2 ) n —O—R f , C 3 -C 8 -alkenyl-O—R f , —(CH 2 ) n —NR g R h , —C 2 -C 6 -alkenyl-NR g R h , or —(CH 2 ) n —R e ; R a is —O—C 1 -C 7 -alkyl or —OH; R b is C 1 -C 7 -alkyl, NH 2 , or —O—C 1 -C 7 -alkyl; R c is —OH, NH 2 , or NH—(CO)—O—C 1 -C 7 -alkyl; R d is C 1 -C 7 -alkyl, —NH 2 , —NH—C 1 -C 7 -alkyl, or —N-di(C 1 -C 7 -alkyl); R e is —OH, —CH 2 F, —CHF 2 , —CF 3 , or —O—(CO)—C 1 -C 7 -alkyl; R f is C 1 -C 7 -alkyl, C 3 -C 8 -alkenyl, C 3 -C 6 -cycloalkyl, phenyl, benzyl, or —(CO)—R′; R g and R h are each independently H, C 1 -C 7 -alkyl, C 3 -C 6 -cycloalkyl, C 3 -C 8 -alkenyl, phenyl, benzyl, or —(CO)—R′ or R g and R h , together with the nitrogen atom to which they are attached, form a 5- to 7-membered heterocyclic or heteroaryl ring optionally substituted with 1 or 2 OH; R′ is NH 2 , —NH—C 1 -C 7 -alkyl, C 1 -C 7 -alkyl, or C 1 -C 7 -alkoxy; m is 1 to 4; and n is 2 to 6; or a pharmaceutically acceptable salt thereof.