Patent ID: 6992205

Claim:
A method of producing a sulfonic acid ester derivative represented by the general formula (5): wherein A represents a phenyl group, which may be substituted, B and B′ are the same or different and each represents a phenyl group, which may be substituted, a straight or branched alkyl group containing 1 to 4 carbon atoms or a hydrogen atom, E represents a straight or branched alkylene group containing 1 to 8 carbon atoms, which may be substituted, F represents a straight or branched alkyl group containing 1 to 8 carbon atoms, which may be substituted and R represents a methanesulfonyl, ethanesulfonyl, p-toluenesulfonyl or p-nitrobenzenesulfonyl group, which comprises reacting an amino alcohol derivative represented by the general formula (2): wherein A, B, B′, E and F are as defined above, with an organic sulfonyl halide represented by the general formula (3): R—X wherein R is as defined above and X represents a chlorine, bromine or iodine atom, in a mixed solvent composed of an aprotic organic solvent and water in the presence of a non-water-prohibiting inorganic base.