Patent ID: 8765752

Claim:
A compound of Formula (II)-3a-1: wherein q is an integer of 0 to 4; s is an integer of 0 to 2; R 8 s are independently a C 1-6 alkoxy group which is substituted with 1 to 5 substituent(s) RIII, an aralkyloxy group, a heterocyclic oxy group (the heterocyclic oxy group is optionally substituted with 1 to 3 C 1-6 alkyl group(s) or 1 to 3 oxo group(s)), or a heterocyclic group (the heterocyclic group is optionally substituted with 1 to 3 C 1-6 alkyl group(s)); the substituent RIII is a group optionally selected from —OH, a C 1-6 alkoxy group, an aryl group (the aryl group is optionally substituted with 1 to 3 halogen atom(s)), a heterocyclic group (the heterocyclic group is optionally substituted with 1 to 3 C 1-6 alkyl groups or 1 to 3 oxo groups), a —S(O) i R a (i is an integer of 0 to 2) group, a —SO 2 NR d R e group, a —CONR d R e group, and a —NR b1 R c1 group; R 9 s are independently a group arbitrarily selected from a halogen atom, a cyano group, a C 1-6 alkyl group (the C 1-6 alkyl group is optionally and arbitrarily substituted with 1 to 5 halogen atom(s), 1 to 5 —OH or 1 to 5 C 1-6 alkoxy group(s)), a C 1-6 alkoxy group (the C 1-6 alkoxy group is optionally and arbitrarily substituted with 1 to 5 halogen atoms(s)), a C 2-6 alkenyl group, a C 2-7 alkanoyl group, a group: —S(O) i R a (i is an integer of 0 to 2), a group: —CONR d R e and a group: —NR b1 R c1 ; R a is a group arbitrarily selected from a C 1-6 alkyl group and a halogenated C 1-6 alkyl group; R d and R e are independently a hydrogen atom or a C 1-6 alkyl group (the C 1-6 alkyl group is optionally substituted with 1 to 5 halogen atom(s), 1 to 5 —OH or 1 to 5 C 1-6 alkoxyl group(s)); R b1 and R c1 are independently a group arbitrarily selected from a hydrogen atom, a C 1-6 alkyl group, a C 2-7 alkanoyl group and a C 1-6 alkylsulfonyl group, or R b1 and R c1 optionally form together with a nitrogen atom to which R b1 and R c1 are bonded, a 3- to 8-membered cyclic group, where in the cyclic goup, one or two carbon atom(s) is(are) optionally substituted with an atom arbitrarily selected from an oxygen atom, a sulfur atom, and a nitrogen atom (the nitrogen atom is optionally substituted with a C 1-6 alkyl group) or with a carbonyl group; a ring A″ is a benzene ring, a pyridine ring, or a pyrimidine ring; the broken line indicates the bonding position of R 8 , and the numbers of “1” to “6” indicate the bonding position of the substituents (with the proviso that compounds of 3-hydroxy-5-[4-[(4-phenoxy-2,3-dihydro-1H-inden-1-yl)oxy]phenyl]isothiazole 1-oxide, 3-hydroxy-5-[4-[[4-(2-methylpyridin-3-yl)oxy-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]isothiazole 1-oxide, 3-hydroxy-5-[4-[[4-(2-methoxypyridin-4-yl)oxy-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]isothiazole 1-oxide, and 3-hydroxy-5-[4-[(4-pyridin-4-yl)oxy-2,3-dihydro-1H-inden-1-yl)oxy]phenyl]isothiazole 1-oxide, are excluded)), or a pharmaceutically acceptable salt of the compound, or a pharmaceutically acceptable solvate of the salt or a pharmaceutically acceptable solvate of the compound.