Patent ID: 8293522

Claim:
A device for binding a target entity onto a bait entity that is immobilized on said device, comprising: a) a lipid layer which comprises one or more lipids, said lipid layer having a negative net charge in an aqueous solution at a neutral pH; b) a two-dimensional matrix of anchoring complexes that are bound to said lipid layer, wherein each of said anchoring complexes comprises: (i) a fusion complex comprising an Annexin protein fused to a partner molecule, wherein: said Annexin protein is bound to said lipid layer, and said partner molecule consists of an organic or a mineral compound; (ii) a bait entity selected from the group consisting of: said partner molecule that is fused to said Annexin protein; a molecule that is covalently or non-covalently bound to said partner molecule; a molecule that is indirectly bound to said partner molecule through one or more intermediate molecules that are covalently or non-covalently bound to said partner molecule.