Patent ID: 8642590

Claim:
A compound of formula I wherein R 1 is C 1-12 -alkyl, unsubstituted or substituted with one or more halo, hydroxy, cyano or C 1-12 -alkoxy, C 3-7 -cycloalkyl, unsubstituted or substituted by one or more substituents independently selected from B, 4-7 membered heterocycloalkyl containing one or two heteroatoms selected from O, N and S, which heterocycloalkyl is unsubstituted or substituted by one or more substituents independently selected from B, R 2 is H, C 1-12 -alkyl, unsubstituted or substituted with one or more OH, halo, cyano or C 1-12 -alkoxy, —(CH 2 ) q —R a , wherein R a is phenyl or 5- or 6-membered heteroaryl, each of which is unsubstituted or substituted with one or more substituents independently selected from A, —(CH 2 ) r NR i R ii , —C(O)—C 1-12 -alkyl, wherein alkyl is unsubstituted or substituted with one or more OH, halo, cyano or C 1-12 -alkoxy, —C(O)(CH 2 ) q OC(O)—C 1-12 -alkyl, —C(O)(CH 2 ) q NR i R ii , —C(O)O—C 1-12 -alkyl, wherein alkyl is unsubstituted or substituted with one or more OH, halo, cyano or C 1-12 -alkoxy, —S(O) 2 —C 1-12 -alkyl, or —S(O) 2 NR i R ii , R i and R ii are each independently H, C 1-12 -alkyl, or together with the nitrogen to which they are bound form a 3- to 7-membered heterocycloalkyl containing one or two heteroatoms selected from N, O and S, which heterocycloalkyl is unsubstituted or substituted by one or more substituents independently selected from B, q is 1, 2, 3 or 4, r is 2, 3 or 4, A is halo, cyano, OH, C 1-7 -alkyl, halo-C 1-7 -alkyl, or C 1-7 -alkoxy, B is oxo, halo, OH, C 1-7 -alkyl or C 1-7 alkoxy, and R 3 is Cl or F, or a pharmaceutically acceptable salt thereof.