Patent ID: 7422878

Claim:
A process for producing ubiquinone-10, which comprises: obtaining a microorganism belonging to the species Rhodobacter sphaeroides having the ability to form ubiquinone-10 and having a disrupted chromosomal geranylgeranyl pyrophosphate synthetase gene, wherein geranylgeranyl pyrophosphate synthetase activity is defective; transforming the microorganism with a DNA selected from the group consisting of: (a) a DNA encoding a polypeptide comprising an amino acid sequence having at least 95% homology to the amino acid sequence shown in SEQ ID NO:2 and having decaprenyldiphosphate synthetase activity, and (b) a DNA encoding a polypeptide comprising an amino acid sequence having at least 95% homology to the amino acid sequence shown in SEQ ID NO:4 and having p-hydroxybenzoic acid-decaprenyltransferase activity; culturing the transformed microorganism in culture; allowing ubiquinone-10 to form and accumulate in the culture; and recovering ubiquinone-10 from the culture.