Patent ID: 8455208

Claim:
A method for determining whether a thyroid nodule in a subject is a follicular thyroid adenoma (FTA) or a follicular thyroid carcinoma (FTC), said method comprising: determining the abundance of a marker protein in a sample obtained from the subject, wherein the sample comprises a thyroid nodule, a tissue, a fluid sample, or a combination thereof, and wherein the marker protein comprises hexokinase-1, glucosidase 2 beta subunit, aminoacylase-1, HSP 90-beta, cytosolic nonspecific dipeptidase, p100 co-activator, and 26S proteasome non-ATPase regulatory subunit 13; and comparing the abundance of the marker protein to a reference level of the marker protein to determine whether the thyroid nodule in the subject is FTA or FTC.