Patent ID: 7728029

Claim:
A compound of formula (I): wherein: R 1 is hydrogen; R 2 is adamantane substituted with hydroxy, alkoxy, halogen, amino, loweralkyl-acylamino or loweralkylsulfonylamino; R 3 is lower alkyl, branched or unbranched, halogen, halo-lower alkyl, 3- to 8-membered heteroaryl having 1-3 heteroatoms selected from N, O and S, which may be unsubstituted or substituted with halogen or lower alkyl, —NH(CH 2 ) n OH, —NH(CH 2 ) n OCH 3 , —NHCH(CH 3 ) 2 , —NH(CH 2 ) n CH 3 OH, —NH(CH 3 )(CH 2 ) n OCH 3 , —NH(CH 3 )(CH 2 ) n OH, —NCH 2 CH(CH 3 )OH, —NH(CH 2 ) n O(CH 2 ) n CH 3 , —N(CH 2 CH 3 ) 2 , —(CH 2 )OH, —(CH 2 )O(CH 2 ) n CH 3 , —(CH 2 )O(CH 2 ) n -alkyl, —(CH 2 )O(CH 2 ) n -cycloalkyl, or a 3- to 8-membered monocyclic heterocycle with 1-3 hetero atoms selected from N, O and S, which may be unsubstituted or substituted with lower alkyl, hydroxy, hydroxy phenyl, —(CH 2 ) n -phenyl, —CH 2 (CH 2 ) n OH or halogen; R 4 is lower alkyl, branched or unbranched, unsubstituted or substituted with hydroxyl, —(CH 2 ) m —(C 3 -C 6 )cycloalkyl, unsubstituted or substituted with hydroxy or lower alkyl, halo-alkyl, hydroxyalkyl, —(CH 2 ) n O(CH 2 ) n CH 3 , —(CH 2 ) n O(CH 2 ) p O(CH 2 ) n CH 3 , —(CH 2 ) n OC(CH 3 ) 3 or —CH(CH 3 ) 2 (CH 2 ) n OH; saturated heterocyclyl ring containing 4-6 atoms of which 1-2 are selected from N, O or S; R 5 is hydrogen or lower alkyl, unsubstituted or substituted with halogen; n is 0, 1, 2 or 3; m is 0, 1 or 2; and p is 1, 2 or 3, or a pharmaceutically acceptable salt thereof.