Patent ID: 7772406

Claim:
A process for production of a benzyloxypyrrolidine of the formula (2), comprising reacting a pyrrolidinol represented by the formula (1) with a benzyl halide in the presence of an alkali metal hydroxide, wherein the reaction is carried out in an aprotic polar solvent; wherein R 1 represents a group selected from i) hydrogen, ii) alkyl group and iii) aryl group; R 2 represents a group selected from i) hydrogen, ii) alkoxy group having carbon numbers of from 1 to 4, iii) alkenyloxy group having carbon numbers of from 2 to 4, iv) aralkyloxy group having one benzene ring, v) alkyl group having carbon numbers of from 1 to 4 and vi) aryl group having one benzene ring; and a hydroxyl group may be either 2 or 3 position of pyrrolidine ring; wherein R 1 represents a group selected from i) hydrogen, ii) alkyl group and iii) aryl group; and R 2 represents a group selected from i) hydrogen, ii) alkoxy group having carbon numbers of from 1 to 4, iii) alkenyloxy group having carbon numbers of from 2 to 4, iv) aralkyloxy group having one benzene ring, v) alkyl group having carbon numbers of from 1 to 4 and vi) aryl group having one benzene ring; R 3 represents a group selected from i) hydrogen, ii) alkyl group having carbon numbers of from 1 to 4, iii) alkoxy group having carbon numbers of from 1 to 4 and iv) halogen group.