Patent ID: 8062890

Claim:
An array useful for culturing cells in culture, the array comprising a self-assembled monolayer of molecular species, each comprising an attachment moiety common among all of the species, an alkane spacer moiety common among all of the species and a ligand moiety that varies among at least three of the species and is covalently attached to the spacer moiety such that all molecular species within an array element are presented on the array surface in a uniform orientation, the monolayer arranged on an inert substrate with the attachment group of each species attached to the substrate; wherein, in some areas of the array, the ligand moiety of the species are cytophobic and solvophobic to create background areas of the array; and wherein, in other areas of the array, the ligand moiety of the species have ligands which may bind to cells oriented away from the substrate and available for binding to living cells.