Patent ID: 7989463

Claim:
A compound of formula (I), a stereoisomer of a compound formula (I), a pharmaceutically acceptable salt of a compound of formula (I), or a pharmaceutically acceptable salt of a stereoisomer of a compound of formula (I); wherein R 1 is —R, —OR, or —NR a R b ; R 2 is R is selected from an optionally substituted group selected from alkyl, cycloalkyl, aryl, heteroaryl or heterocyclyl, wherein one or more optional substituents on R are selected from halogen, hydroxy, cyano, alkyl, haloalkyl, cycloalkyl, —CO-alkyl, —(CH 2 ) r —OH, —(CH 2 ) r -alkoxy, aryl, heteroaryl, —(CH 2 ) r SO 2 NR f R g or —(CH 2 ) r SO 2 R h ; A is a 3- to 7-member cycloalkyl ring; R a and R b are each independently selected from hydrogen, —(CH 2 ) r -hydroxy, —(CH 2 ) r -halogen, and an optionally substituted group selected from alkyl, —(CH 2 ) r -cycloalkyl, —(CH 2 ) r -heterocyclyl, —(CH 2 ) r -aryl or —(CH 2 ) r -heteroaryl, wherein one or more optional substituents on R a and R b are each independently selected from halogen, hydroxy, cyano, alkyl, haloalkyl, cycloalkyl, —CO-alkyl, —(CH 2 ) r —OH, —(CH 2 ) r -alkoxy, aryl, heteroaryl, —(CH 2 ) r SO 2 NR f R g or —(CH 2 ) r SO 2 R h ; or R a and R b optionally combine with the nitrogen atom, to which they are attached, to form an optionally substituted 5- to 6-membered heterocyclic ring optionally having 1 to 3 additional hetero atoms or groups selected from nitrogen, oxygen, sulfur, SO 2 or CO, wherein one or more optional substituents on the 5- to 6-membered heterocyclic ring are selected from halogen, hydroxy, alkyl, haloalkyl, —CO-alkyl, —(CH 2 ) r —OH or —(CH 2 ) r -alkoxy; R c is selected from hydrogen or alkyl; R d is selected from cyano, —(CH 2 ) r —OH, —(CH 2 ) r -alkoxy, alkyl, aryl, —NH-aryl, heteroaryl, —(CH 2 ) r CO-alkyl, —(CH 2 ) r COOR e , —(CH 2 ) r CONR f R g , —(CH 2 ) r SO 2 NR f R g or —(CH 2 ) r SO 2 R h ; R e is selected from hydrogen, alkyl, cycloalkyl, aryl, heterocyclyl or heteroaryl; R f and R g are each independently selected from hydrogen or an optionally substituted group selected from alkyl, cycloalkyl, alkoxy, aryl, heteroaryl or heterocyclyl, wherein one or more optional substituents on R f and R g are each independently selected from halogen, hydroxyl or alkyl; R h is selected from alkyl, cycloalkyl, aryl, heterocyclyl or heteroaryl; m is an integer from 0 to 2; n is an integer from 1 to 3; and r is an integer from 0 to 3.