Patent ID: 7414063

Claim:
A compound of Formula (I): wherein: R 1 is hydrogen, halo, amino or hydroxy; R 2 is hydrogen, C 1 -C 4 alkyl, or C 2 -C 4 alkenyl, wherein said C 1 -C 4 alkyl is optionally substituted with carboxyl, trifluoro, benzyl, acetamide, C 1 -C 4 alkoxycarbonyl, substituted C 1 -C 4 alkoxycarbonyl, wherein the substitution is C 1 -C 4 alkyl, or —NR 9 R 10 , wherein R 9 and R 10 are each independently hydrogen or C 1 -C 4 alkyl; R 3 is hydrogen, or C 1 -C 4 alkyl; R 4 is hydrogen, halo, C 1 -C 4 alkyl, or C 1 -C 4 alkoxy; R 5 is hydrogen, halo, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, trifluoromethyl, or nitro, or R 4 and R 5 , together with the carbon atoms to which they are attached, form a benzo-fused ring; R 6 is selected from the group consisting of hydrogen, halo, C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 1 -C 4 alkoxy, trifluoromethyl, nitro, cyano, C 3 -C 6 cycloalkyl, phenyl, phenoxy, phenethyl, benzyl, benzoyl, isoxazolyl, furyl, thienyl, and methylsulfonyl; wherein said C 1 -C 4 alkyl group may be substituted by N-morpholino, piperidine, pyrrolidine, or NR 9 R 10 ; wherein said thienyl group may be substituted by halo or C 1 -C 4 alkyl; and wherein said phenyl, benzoyl or benzyl group may be substituted with one to two substituents independently selected from the group consisting of halo, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, CF 3 , amino, nitro, hydroxy, methylsulfonylamino, sulfonamido, and C(O)R 11 ; wherein R 11 is selected from the group comprising N-morpholino, hydroxy or NR 9 R 10 ; X is —O—, —S(O) p —, or —NR 8 —; n is 2 or 3; p is 0, 1, or 2; R 7 is hydrogen, methyl, ethynyl, phenyl, thienyl or pyrazole; wherein said phenyl, thienyl or pyrazole may be substituted by hydroxy, halo or amino; R 8 is hydrogen, C 1 -C 4 alkyl, benzyl or tert-butyl ester; or a pharmaceutically acceptable salt thereof.