Patent ID: 8716493

Claim:
A compound of Formula IIIa: or a pharmacologically acceptable salt thereof, wherein: each of A and B is, independently, C(═O); E and F, together with the carbon atoms to which they are attached, form: a substituted or unsubstituted C 5 cycloalkyl group; R 1 is hydrogen; R 2 is lower alkyl having at least one substituent J 4 ; J is independently at each occurrence: J 3 -(J 2 ) n -(J 1 ) m - wherein each of n and m is, independently, 0 or 1; each of J 1 and J 2 is, independently, carbonyl, lower alkylcarbonyl, arylcarbonyl, carbonyloxy, amino, lower alkylamino, lower dialkylamino, amido, lower alkylamido, lower dialkylamido, lower alkoxy, lower alkyl, C 3 to C 7 cycloalkyl, heterocycloalkyl, aryl, or a heteroaryl; and J 3 is: hydrogen, halo, hydroxy, cyano, NO 2 , carboxyl, lower alkyl, aryloxycarbonyl, alkyloxycarbonyl, heteroaryl, or heterocycloalkyl; and J 4 is lower alkylcarbonyl, arylcarbonyl, amino, lower alkylamino, lower dialkylamino, amido, lower alkylamido, lower dialkylamido, lower alkoxy, lower alkyl, C 3 to C 7 cycloalkyl, heterocycloalkyl, aryl, or a heteroaryl; and X 1 and X 2 , together with the atoms to which they are attached, form: a substituted or unsubstituted phenyl group wherein said substituted phenyl group has at least one substituent J; or a substituted or unsubstituted heteroaryl group wherein said substituted heteroaryl group has at least one substituent J and where said heteroaryl is pyridine or pyridine-N-oxide.