Patent ID: 8389513

Claim:
A compound of formula I, wherein R 1 is selected from the group consisting of i) aryl, ii) aryl substituted by 1-4 substituents individually selected from cyano, cyano-lower alkyl, halogen, halogen-lower alkoxy, halogen-lower alkyl, lower alkoxy, lower alkoxy-lower alkyl and lower alkyl, iii) heteroaryl, iv) heteroaryl substituted by 1-4 substituents individually selected from amido, cyano, cyano-lower alkyl, cycloalkyl, cycloalkyl-lower alkenyl, cycloalkyl-lower alkynyl, cycloalkyl-lower alkyl, cycloalkyl-lower alkoxy, halogen, halogen-lower alkoxy, halogen-lower alkyl, lower alkoxy, lower alkoxy-lower alkyl, lower alkenyl, lower alkynyl, lower alkyl and nitro; v) lower alkyl, vi) lower alkyl substituted by 1-5 substituents individually selected from cyano, halogen, hydroxy and lower alkoxy; vii) lower alkenyl, viii) lower alkenyl substituted by 1-4 substituents individually selected from cyano, cyano-lower alkyl, halogen, halogen-lower alkoxy, halogen-lower alkyl, heteroaryl, lower alkoxy, lower alkoxy-lower alkyl and lower alkyl, ix) cycloalkyl, and x) cycloalkyl substituted by 1-4 substituents individually selected from cyano, cyano-lower alkyl, halogen, halogen-lower alkoxy, halogen-lower alkyl, lower alkoxy, lower alkoxy-lower alkyl and lower alkyl, R 2 is selected from the group consisting of i) hydrogen, ii) halogen, and iii) lower alkyl; R 3 is lower alkyl; R 4 is selected from the group consisting of i) hydrogen, and ii) lower alkyl; R 5 is selected from the group consisting of i) hydrogen, and ii) lower alkyl; and n is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.