Patent ID: 7608594

Claim:
The compounds according to Formula I wherein R 1 is hydrogen, alkyl, alkenyl, alkynyl, carbocyclic, heterocyclic, aryl, aralkyl, carboxyl, amido, amino, sulfanyl, sulfenyl, sulfonyl, or ether; or R 1 together with X 2 and the atom to which R 1 is attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; or R 1 together with X 4 and the atom to which R 1 is attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein R 2 is hydrogen or hydroxy; wherein R 3 is hydrogen or hydroxy; wherein R 4 is hydrogen, methyl, hydroxy, carboxyl, —R 12 —O—R 13 , or —R 12 —R 14 , wherein R 12 is a covalent bond or alkyl, and R 13 is C-amido or acyl, and R 14 is N-amido, —POR 15 R 16 , —SO 2 R 17 , or sulfonamido and wherein R 15 , R 16 , R 17 are independently alkoxy; wherein R 5 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or aralkyl; wherein R 6 is hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, alkoxy, aryloxy, or aralkoxy; wherein X 1 is —O—, —CO—, or —N—; wherein X 2 is —O—, —N—, —NR 18 —, —CR 19 —, or —CO—, wherein R 18 and R 19 is hydrogen, alkyl, alkenyl, alkynyl; or X 2 together with R 1 and the atom to which R 1 is attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein X 4 is —O—, —CR 20 —, —CO—, or —N—, wherein R 20 is hydrogen, alkyl, alkenyl, alkynyl, or wherein X 4 together with R 1 and the atoms to which they are attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein X 5 , is —CR 21 — or —N—, wherein R 21 is hydrogen, alkyl, alkenyl, alkynyl; wherein X 6 , is —CR 22 — or —N—, wherein R 22 is hydrogen, alkyl, alkenyl, alkynyl, alkoxy, aryl, aralkyl, halogen, or nitro; or X 6 together with X 9 and the carbon at position 7 form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein X 8 , is —CR 23 — or —N—, wherein R 23 is hydrogen, alkyl, alkenyl, alkynyl; wherein X 9 is alkyl, alkenyl, alkynyl, ether, secondary or tertiary amino, or sulfanyl; or X 9 together with X 6 and the carbon at position 7 form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; and wherein at least one of X 1 , X 2 , X 4 , X 5 , X 6 , X 8 is not —CR—; wherein n is 0, 1, 2, or 3.