Patent ID: RE45272

Claim:
A ligand drug conjugate compound having the formula: L A a —W w —Y y —D 1-4 ) p or a pharmaceutically acceptable salt or solvate thereof, wherein: L- is a Ligand unit; -A a -W w —Y y — is a Linker unit (LU), -A- is an optional Stretcher unit, a is 0, 1 or 2, each —W— is independently a Glucuronide unit having one of the formulae: Su is a Sugar moiety ; each R is independently hydrogen, a halogen, —CN, or —NO 2 ; w is an integer ranging from 1 to 2, —Y— is an optional self-immolative spacer unit, y is 0, 1 or 2; p ranges from 1 to 20; -D is a Drug unit and wherein the wavy lines indicates indicate covalent attachment within the rest of the compound.