Patent ID: 7655679

Claim:
A compound of formula I wherein: R1 is selected from the group consisting of H, halogen, (C1-C8) alkyl, (C1-C4) alkylene-O—(C1-C4) alkylene-H, SCH 3 , and CN, wherein the alkyl and alkylene groups are unsubstituted or optionally mono, di- or tri-substituted by F; R2, R3 and R4 are independently selected from the group consisting of H, halogen, (C1-C8) alkyl, (C1-C4) alkylene-O—(C1-C4) alkylene-H, SCH 3 , and CN, wherein the alkyl and alkylene are unsubstituted or mono, di- or tri-substituted by F; X is —CH2— or —CH2—CH2—; U is S or O; R5 is selected from the group consisting of H, (C1-C8) alkyl, (C1-C4) alkylene-O—(C1-C4) alkyl, (C1-C4) alkylene-O—(C1-C4) alkylene-(C6-C10) aryl, (C1-C4) alkylene-(C3-C12) cycloalkyl, (C2-C8) alkenyl, (C1-C4) alkylene-(C3-C15) heterocycloalkyl, (C1-C4) alkylene-(C3-C15) heterocycloalkenyl, and (C1-C4) alkylene-(C5-C15) heteroaryl, wherein the alkyl and alkylene are unsubstituted or mono-, di- or tri-substituted by F, N((C1-C4) alkylene-H)—(C1-C4) alkylene-H or O—(C1-C4) alkylene-H, and wherein the cycloalkyl, aryl, heterocycloalkyl, heterocycloalkenyl and heteroaryl are unsubstituted or mono-, di- or tri-substituted by a moiety selected from the group consisting of F, Cl, Br, CF 3 , (C1-C4) alkyl, CO—(C1-C4) alkyl and (C1-C4)-alkylene-O—(C1-C4) alkylene-H; and R6 and R7 are is selected from the group consisting of H and (C6-C14) aryl which may be unsubstituted or mono-, di- or tri-substituted by a moiety selected from the group consisting of F, Cl, Br, CF 3 , (C1-C4) alkyl and (C1-C4)-alkylen-O—(C1-C4) alkylene-H; or R6 and R7 together with the oxazole or thiazole ring form a benzothiazole or benzoxazole ring, which is unsubstituted or mono-, di- or tri-substituted by F, Cl, Br, CF 3 , (C1-C4) alkyl or (C1-C4)-alkylen-O—(C1-C4) alkylene-H; or a stereoisomeric form thereof, an enantiomeric form thereof or a mixture in any ratio thereof, or a physiologically acceptable salt or a tautomeric form thereof.