Patent ID: 7163810

Claim:
A method for producing an L-amino acid in a bacterium comprising a) culturing the bacterium in a medium that contains methanol as a carbon source. b) producing and accumulating the L-amino acid in the medium or within cells of the bacterium, and c) collecting the L-amino acid from the medium or the cells of the bacterium, using a bacterium that has: i) a methanol dehydrogenase gene introduced to impart or enhance an ability to utilize methanol as compared to a wild-type bacterium, and ii) been modified so that activities of hexulose phosphate synthase and phosphohexuloisomerase are enhanced as compared to a wild-type bacterium by: increasing the copy number of the genes coding for hexulose phosphate synthase and phosphohexuloisomerase, replacing expression regulatory sequences of the genes coding for hexulose phosphate synthase and phosphohexuloisomerase with stronger expression regulatory sequences or a combination of modifications thereof.