Patent ID: 8404485

Claim:
An article for cell culture, comprising: a base; and a polymeric coating grafted to the base via a polymerization initiator or a remnant thereof the polymeric coating comprising a swellable (meth)acrylate polymer having an equilibrium water content of between 5% and 70% wherein the polymeric coating is formed from a mixture of monomers comprising a carboxyl group-containing (meth)acrylate monomer, a cross-linking (meth)acrylate monomer, and a hydrophilic monomer capable of polymerizing with the carboxyl group-containing (meth)acrylate monomer and the cross-linking (meth)acrylate monomer, wherein the weight percentage of the polymer derived from the hydrophilic monomer is between 60% and 90%, the weight percentage of the polymer derived from the carboxyl group-containing monomer is between 10% and 40%, and the weight percentage of the polymer derived from the cross-linking monomer is between 1% and 10%; and, a cell adhesive polypeptide having an RGD sequence to the polymer.