Patent ID: 7135341

Claim:
A cell treatment composition for altering a nucleus property comprising: (a) a conditioning component; (b) a lytic component comprising a quaternary ammonium surfactant in an amount enabling permeating cell membrane and reducing a size of a blood cell to substantially a size of cell nucleus thereof; said quaternary ammonium surfactant being represented by following molecular structure: wherein R 1 is an alkyl, alkenyl or alkynyl group having 12 to 16 carbon atoms: R 2 , R 3 and R 4 are alkyl groups having 1 to 4 carbon atoms and X − is chloride or bromide anion; and (c) a fixing component for preserving said cell nucleus; wherein said conditioning component, said lytic component, and said fixing component are present at predetermined respective concentrations to alter a nucleus property from a natural value to a target value upon contacting with said cell nucleus.