Patent ID: 6953784

Claim:
A therapeutic composition comprising: an injectable biodegradable carrier, said carrier comprising a first polysaccharide cross-linked to a second polysaccharide, wherein said first and second polysaccharides is each a member selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparin, heparan sulfate and alginate; and wherein said first and second polysaccharides are covalently cross-linked to each other through imine bonds between amino groups on said second polysaccharide and aldehyde groups from oxidized sugar rings on said first polysaccharide; and a therapeutic agent selected from the group consisting of growth factors, cytokines, hormones, DNA constructs, and autologous, allogenic or modified cells.