Patent ID: 7582772

Claim:
A method for making a compound of formula 1: said method comprising the steps of: a) reacting compounds of formulas 2 and 3: to produce a compound of formula 4: wherein: R 1 , R 2 , R 3 , and R 4 each is independently selected from the group consisting of H, halogen, —CN, —CHO, —CF 3 , —OCF 3 , —OH, —NO 2 , —C 1-6 alkyl, —C 1-6 alkoxy, —NH 2 , —NH(C 1-6 alkyl), —N(C 1-6 alkyl) 2 , and —NHC(O)—C 1-6 alkyl; and R 5 is selected from the group consisting of H and —C(O)O—C 1-6 alkyl, said reaction occurring in the presence of a base, a palladium catalyst, and a copper catalyst, wherein at least about 2 or more equivalents of the base are present; and b) converting the compound of formula 4 to the compound of formula 1.