Patent ID: 6943167

Claim:
A fused bicyclo compound having the structure: or pharmaceutically acceptable salt or stereoisomer thereof, wherein Y is —N(R 3 )—; A is —(CR 4 R 4a ) m —; B is —(CR 5 R 5a ) n —; m is 2; n is 1; R 4 and R 5a are, at each occurrence, the same or different and independently an amino acid side chain moiety or an amino acid side chain derivative; R 4a and R 5a are, at each occurrence, the same or different and independently hydrogen, hydroxy, —COOH, —CONH 2 , —R 6 , —OR 6 , —COOR 6 , —COR 6 or —CONHR 6 ; R 6 is a lower alkyl optionally substituted with halogen or hydroxy; R 2 is -Z-(amino acid side chain moiety) or -Z-(amino acid side chain derivative), where Z is a direct bond or —C(═)O—, —C(═O)O—, —C(═O)NH—, —C(═NH)—, —SO 2 — or —P(O) 2,3 —; and R 1 and R 3 are the same or different and independently an amino acid side chain moiety, an amino acid side chain derivative, a peptide, a peptide derivative, a protein, -Z-(amino acid side chain moiety) or -Z-(amino acid side chain derivative), wherein Z is a direct bond or —C(═O)—, —C(═O)O—, —C(═O)NH—, —C(═NH)—, —SO 2 — or —P(O) 2,3 —; and wherein any two adjacent CH groups or adjacent NH and CH groups of the fused bicyclo compound optionally form a double bond.