Patent ID: 8755938

Claim:
A method of performing by a patient managing a chronic disease a structured collection protocol on a collection device comprising a processor, wherein the method comprises: receiving on the collection device a selection of a selected structured collection protocol from a plurality of structured collection protocols, wherein each of the structured collection protocols specify sequential collection events over a collection period in which to collect samples of biomarker data which is useful to address a particular situation or problem the patient is having with management of the chronic disease; automatically determining, via the processor, an acceptable range of values for a future collected sample from an evaluation of at least one sampling set of biomarker data having a plurality of collected samples recorded over a previous collection period in compliance with adherence criteria for the selected structure collection protocol and read by the processor from a memory, wherein the adherence criteria establishes at least one procedural steps leading up to taking of a sample according to the selected structure collection protocol in order for the future collected sample to be useful in an evaluation addressing the situation or problem of the selected structure collection protocol; querying the patient via a display unit operatively coupled to the processer of the collection device regarding compliance with the adherence criteria of the selected structure collection protocol; receiving on the collection device a result from the querying; starting on the collection device a new collection period and instructing on the display unit for the patient to collect at least one sample for a new sampling set of biomarker data that the processor stores in the memory; comparing, via the processor, the collected sample to the acceptable range if the result from the querying indicates compliance with the adherence criteria; informing, via the display unit, the patient if the collected sample is an unacceptable value which falls outside of the acceptable range; performing, via the processor, at least one additional task after detecting the unacceptable value; storing, via the processor, in the memory the collected sample as part of the new sampling set of biomarker data; indicating, via the processor, in the memory the collected sample as being acceptable if falling within the acceptable range; and if the at least one additional task is not to terminate the structure collection protocol, checking, via the processor, to see if the new collection period has ended otherwise continuing with a next sample to be collected at an event specified in the selected structured collection protocol, wherein the new collection period ends upon a predetermined number of sampling values in the new sampling set being indicated in the memory as acceptable such that a new acceptable range of values for another future collected sample in another future collection period is determinable from evaluating at least the new sampling set of the biomarker data.