Patent ID: RE42350

Claim:
A method for producing L-glutamic acid by fermentation, which comprises culturing an isolated microorganism in a liquid medium of which pH is adjusted to the pH at which L-glutamic acid is precipitated, to produce and accumulate L-glutamic acid and precipitate L-glutamic acid in the medium, wherein said microorganism can metabolize a carbon source at a specific pH in a liquid medium containing the carbon source and L-glutamic acid at a saturation concentration, and has the ability to accumulate L-glutamic acid in an amount exceeding the amount corresponding to the saturation concentration in the liquid medium at the pH, wherein said microorganism is Enterobacter agglomerans Pantoea ananatis , and wherein said microorganism has at least one of the following characteristics: (a) the microorganism has increased activity, as compared to a corresponding wild-type microorganism, of an enzyme that catalyzes a reaction for biosynthesis of L-glutamic acid; and (b) the microorganism has decreased activity, as compared to a corresponding wild-type microorganism, or deficient activity of an enzyme that catalyzes a reaction of a pathway branching from a biosynthetic pathway of L-glutamic acid and producing a compound other than L-glutamic acid.