Patent ID: 8916373

Claim:
A mutant “human superoxide dismutase 1” (hsod1) variant, wherein the wild-type (unmutated) hsod1 has a polypeptide sequence that is at least 80% identical to SEQ ID NO:1, said hsod1 having one or more mutations selected from the group consisting of: a) a substitution of the 21st Glu residue for Gln or Asn; b) a substitution of the 24th Glu residue for Gln or Asn; c) a substitution of the 40th Glu residue for Gln or Asn; d) a substitution of the 77th Glu residue for Gln or Asn; e) a substitution of the 78th Glu residue for Gln or Asn; f) a substitution of the 100th Glu residue for Gln or Asn; g) a substitution of the 121st Glu residue for Gln or Asn; h) a substitution of the 132nd Glu residue for Asn; and i) a substitution of the 133rd Glu residue for Asn.