Patent ID: 7241793

Claim:
A compound of formula (1) or a pharmaceutically acceptable salt, solvate, or hydrolysable ester thereof, wherein: R 1 and R 2 are independently H or C 1-3 alkyl; R 3 and R 4 are independently H, C 1-3 alkyl, OCH 3 , CF 3 , allyl, or halogen; n is 0 or 1 Y is N; Z is N; X is CH; each R 6 is independently C 1-3 alkyl, CF 3 , OCH 3 , OCF 3 , or halogen; y is 0, 1, 2, 3, 4, or 5; R 7 is H, CF 3 , C 2-6 alkenyl; or R 7 is C 1-6 alkyl optionally substituted by phenyl wherein the phenyl is optionally substituted by —O—C 1-3 alkyl; R 10 is H or C 1-3 alkyl; R 5 represents H, C 1-6 alkyl, C 1-3 alkyl —O—C 1-3 alkyl, C 2-6 alkenyl, or C 1-6 alkoxy, each of which may be optionally substituted by one or more halogens; or R 5 is a group —CH 2 -D wherein D is wherein P represents O, N or S, and when P is N, the depicted bond can be attached to the nitrogen in the ring as well as any of the carbons in the ring; or D is wherein R 8 and R 9 independently represent H, halogen, C 1-6 alkyl or —OC 1-6 alkyl.