Patent ID: 8680113

Claim:
A compound of Formula (I): wherein, Ar 1 is phenyl or benzo[1,3]dioxolyl; Ar 2 is thiazolyl or pyrimidinyl substituted with R 4 ; R 1 is hydrogen or one, two, three or four substituents each selected from halogen, cyano, hydroxy, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 1-8 alkoxy, halo-C 1-8 alkyl, halo-C 1-8 alkoxy, hydroxy-C 1-8 alkyl, C 1-8 alkoxy-C 1-8 alkyl, C 1-8 alkoxy-C 1-8 alkoxy, C 1-8 alkoxy-C 1-8 alkoxy-C 1-8 alkoxy, carboxy, amino, C 1-8 alkyl-amino, amino-C 1-8 alkyl, C 1-8 alkyl-amino-C 1-8 alkyl, C 1-8 alkyl-carbonyl, C 1-8 alkoxy-carbonyl, aminosulfonyl, C 1-8 alkyl-aminosulfonyl, C 1-8 alkyl-carbonyl-amino and C 1-8 alkoxy-carbonyl-amino; R 2 is hydrogen or C 1-8 alkyl; R 3 is imidazo[1,2-a]pyridin-3-yl or imidazo[1,2-a]pyrimidin-3-yl each substituted with R 5 and R 6 ; R 4 and R 5 are each hydrogen, C 1-8 alkyl or halo-C 1-8 alkyl; and R 6 is hydrogen or one, two, three or four substituents each selected from halogen, hydroxy or C 1-8 alkyl; or a free acid, free base, salt, ester, hydrate, solvate, chelate, clathrate, isotopologue, geometric isomer, stereoisomer, racemate, enantiomer, diastereomer or tautomer thereof, with the proviso that the compound of Formula (I) is other than: N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, N-(3-chloro-2-methylphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, N-(2,5-dimethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, N-(2-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, N-(2-chlorophenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, 4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-N-m-tolylthiazol-2-amine, N,N-diethyl-N′-(4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-yl)benzene-1,4-diamine, N-(2-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, 1-(3-(4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-ylamino)phenyl)ethanone, 4-(4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-ylamino)benzenesulfonamide, N-(4-(4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-ylamino)phenyl)acetamide, N,N-dimethyl-N′-(4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-yl)benzene-1,4-diamine, N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, N-(4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine, 4-(4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-ylamino)benzoic acid, 4-(4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)thiazol-2-ylamino)phenol, 4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-N-(4-methoxyphenyl)thiazol-2-amine, and 4-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-N-(2-methoxyphenyl)thiazol-2-amine.