Patent ID: 7504430

Claim:
A compound of the following Formula II: wherein: R 1 is selected from hydrogen, amino, thiol, hydroxy, cyano, nitro, carboxylate, carboxamide, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclic aryl, optionally substituted heteroaryl, optionally substituted alkoxy, optionally substituted mercaptoalkyl, optionally substituted mono- or di-alkyl amino, optionally substituted cycloalkyl, optionally substituted heteroalicyclic, or optionally substituted aminoalkyl; R 2 is —X—(CH 2 )n-Y; Ar is phenyl or naphthyl, each of which is substituted with between 0 and 5 substituents independently selected from halogen, amino, hydroxy, cyano, nitro, carboxylate, carboxamide, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclic aryl, optionally substituted heteroaryl, optionally substituted alkoxy, optionally substituted mercaptoalkyl, optionally substituted mono- or di-alkyl amino, optionally substituted cycloalkyl, optionally substituted heteroalicyclic, and optionally substituted aminoalkyl; and with the proviso that if Ar is substituted phenyl than Ar is not para-carboxy substituted phenyl; X is O, S(O) p , NH, or N(C 1-6 alkyl); Y is hydroxy, carboxylate, sulfonate, carboxamide, or amino; n is an integer of from 1 to about 8; and p is 0, 1, or 2, or a pharmaceutically acceptable salt thereof.