Patent ID: 7112586

Claim:
A compound having the formula wherein R 1 , R 2 and X 1 are taken together (with the amine nitrogen), A, X 3 , X 4 and R 3 are selected in concert from the group consisting of R 1, R 2 and X 1 Taken Together (with the amine nitrogen) A X 3 X 4 R 3 1-phenyl-1,2,3,4- 1,3-phenyl- absent CO 4-fluorophenyl tetrahydroisoquinolin- methyl 2-yl 1-phenyl-1,2,3,4- 1,3-n-propyl absent CO 4-fluorophenyl tetrahydroisoquinolin- 2-yl 4-[(4- 1,3-n-propyl absent CO 4-fluorophenyl chlorophenyl)phenyl- methyl]-piperazin-1-yl 2-[1-benzyl-6-methoxy- 1,3-n-propyl absent CO 4-fluorophenyl 1,2,3,4-tetrahydro]- naphthyl 1-phenyl-1,2,3,4- 1,3-n-propyl CO ab- 4-fluorobenzyl tetrahydroisoquinolinyl sent and pharmaceutically acceptable salts, esters and pro-drug forms thereof.