Patent ID: 7504538

Claim:
A compound having the formula: wherein Z′ is —(CH 2 ) 3 — or cyclohexyl; Z is selected from a C 1-7 straight or branched chain alkyl, a C 4-8 branched alkylene chain, and a C 2-7 alkenylene chain; Ar is an aryl group independently selected from an aromatic carbocyclic ring system, a five- or six-membered heteroaromatic ring system and a bicyclic heteroaromatic ring system; R 3 is selected from a group of substituents (a)-(d) consisting of: (a) H; (b) C 1-6 straight chain or C 4-8 branched chain alkyl; (c) C 3-8 cycloalkyl or C 5-8 cycloalkenyl; and (d) C 2-6 alkenyl or alkynyl; wherein the substituents (b)-(d) optionally have at least one substituent independently selected from a group (e)-(i) consisting of: (e) Ar, —O—Ar or —S—Ar; (f) OH, O-alkyl or S-alkyl, where alkyl is selected from the substituents (b)-(c); (g) —NR 4 R 5 , where R 4 and R 5 are independently selected from the substituents (a)-(d) or optionally together form a nitrogen containing ring structure comprising from 2 to 5 carbon atoms; (h) —NH—C(O)-alkyl, —C(O)-alkyl, —O—C(O)-alkyl or —S—C(O)-alkyl, where alkyl is selected from the substituents (b)-(c); and (i)F, Cl or Br; R 6 is selected from a group consisting of Ar and the substituents (a)-(c), where (b) and (c) are optionally substituted with at least one of the substituents (e)-(i); Ar optionally has at least one substituent independently selected from the substituents (b)-(i); or a tautomer, solvate or pharmaceutically acceptable salt of said compound.