Patent ID: 6903092

Claim:
A compound having the formula wherein: R 1 is —OR 6 , —NR 6 R 7 , —NOC 1-4 alkyl or —NR 7 NR 6 R 7 ; R 2 is —OR 6 or C 1-12 alkyl; R 3 is H, halogen, —OR 7 or —CN; R 4 is H, C 1-4 alkyl or —OR 7 ; R 5 is H, or C 1-6 alkyl; R 6 is independently, at each instance, H, C 1-6 alkyl-, R 7 OC(═O)C 1-6 alkyl-, R 7 R 7 NC (═O)C 1-6 alkyl-, R 7 R 7 NC 1-6 alkylNR 7 C(═O)-, R 8—, R 8 C 1-6 alkyl-or —(CH 2 ) m phenyl, wherein the phenyl is substituted by 1, 2 or three substituents selected from C 1-6 alkylthio, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyl, trifluoromethylthio, trifluoromethylsulfinyl,C 1-6 alkanesulfonamido, C 1-6 alkanoyl, C 1-6 alkoxy-carbonyl, succinamido, carbamoyl, C 1-6 alkalcarbamoyl, di-C 1-6 alkylcarbamoyl, C 1-6 alkoxy-C 1-6 alkylcarbamoyl, N-methylcarbamoyl, C 1-6 alkanoylamino, ureido, C 1-6 ureido, di-C 1-6 alkylureido, amino, C 1-6 alkylamino and di-C 1-6 alkylamino; R 7 is independently, at each instance, H, or C 1-6 alkyl; or R 5 and R 7 together are —(CH 2 ) 2 O(CH 2 ) 2 —, —(CH 2 ) 2 S(═O) m (CH 2 ) 2 —, —(CH 2 ) 2 N(CO 2 R 7 )(CH 2 ) 2 — or —(CH 2 ) 2 NR 7 (CH 2 ) 2 —; R 5 is a 5- or 6-membered saturated or unsaturated heterocycle containing 1, 2 or 3 nitrogen atoms and additionally subsituded with 0 or 1 oxo groups; m is independently, at each instance 0, 1 or 2; and X 1 and X 2 are independently H, —CH 3 or halogen; or any pharmaceutically-acceptable salt thereof.