Patent ID: 8163797

Claim:
A method for prophylactic treatment of coronary events, prophylactic treatment of cardiovascular events or therapeutic treatment of hyperlipidemia in a human in need thereof, which method comprises administering to the human an effective amount of a stable oral pravastatin formulation consisting of a physical mixture of 10 wt. % pravastatin sodium, 66 wt. % mannitol, 13 wt. % microcrystalline cellulose, 6 wt. % corn starch, 4 wt. % crospovidone or sodium starch glycolate, and 1 wt. % magnesium stearate, wherein, when an amount of the formulation sufficient to provide 20 mg of pravastatin is dispersed by stirring in 25 mL of room temperature water, the formulation has a pH in the range of about 7 to about 7.5, whereupon said human is treated.