Patent ID: 7311917

Claim:
An isolated or purified outer membrane polypeptide having a molecular weight of about 16 kD to about 20 kD, as determined by reducing SDS-PAGE using trypsin inhibitor and carbonic anhydrase, respectively as 21.5 kD and 31 kD molecular weight standards, said protein designated “OMP21” of Moraxella catarrhalis strain, or an OMP21 polypeptide, wherein said polypeptide is at least 70% wt pure: a) encoded by a nucleic acid sequence as set forth as SEQ ID NO: 6 wherein said polypeptide is recognized by an antibody that specifically binds to the polypeptide having the amino acid sequence as set forth as SEQ ID NO: 7; or b) comprising the amino acid sequence SEQ ID NO: 7 wherein said polypeptide is recognized by an antibody that specifically binds to the polypeptide having the amino acid sequence of SEQ ID NO: 7.