Patent ID: 8664365

Claim:
An anti-EphA3 antibody, comprising: a V H region that comprises a CDR3 having the amino acid sequence GGYYEDFDS (SEQ ID NO:43), SGYYEEFDS (SEQ ID NO:41), SGVYEDFDS (SEQ ID NO:44), SGYYEDFDS (SEQ ID NO:39), SGYYEDFDV (SEQ ID NO:45), or SGYYEDFDI (SEQ ID NO:46); a CDR2 having the amino acid sequence DIYPGSGNTNYDEKFQG (SEQ ID NO:49); and a CDR1 having the amino acid sequence GYWMN (SEQ ID NO:48); and a V L region that comprises a CDR3 having the amino acid sequence GQYANYPYT (SEQ ID NO:57), VQYANYPYT (SEQ ID NO:61), VQYSNYPYT (SEQ ID NO:60), AQYANYPYT (SEQ ID NO:59), VQYAKYPYT (SEQ ID NO:58), VGYANYPYT (SEQ ID NO:62), VRYANYPYT (SEQ ID NO:63), or VQYLNYPYT (SEQ ID NO:64); a CDR2 having the amino acid sequence AASSLQS (SEQ ID NO:68), and a CDR1 having the amino acid sequence RASQGIISYLA (SEQ ID NO:66).