Patent ID: 8183242

Claim:
An aminopyrimidine compound of general formula (I) or pharmaceutically acceptable salts thereof: wherein, R 1 is selected from substituted or unsubstituted aryl, heteroaryl, or heterocycle, in which the substituent is selected from halogen, C 1-4 linear or branched alkyl, amino, alkoxy or cycloalkyl; R 2 and R 3 are independently selected from hydrogen, halogen, amino, alkylamino, dialkylamino, cyano, nitro, hydroxy, alkoxy, haloalkoxy; or substituted or unsubstituted alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl, in which the substituent is selected from halogen, C 1-4 linear or branched alkyl, amino, alkoxy or nitro; R 4 is selected from hydrogen, halogen, amino, alkylamino, dialkylamino, cyano; or substituted or unsubstituted alkyl, cycloalkyl, alkenyl, alkynyl, in which the substituent is selected from halogen, amino or hydroxy; R 5 is selected from hydrogen, halogen, nitro, cyano, hydroxy, alkoxy, methylenedioxy, haloalkoxy, amino; or substituted or unsubstituted alkyl, cycloalkyl, alkenyl, alkynyl, aryl or heteroaryl, in which the substituent is selected from halogen, amino or hydroxy; R 6 is selected from hydrogen, or substituted or unsubstituted alkyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocycle, heterocyclic alkyl, in which the substituent is selected from halogen, amino or C 1-4 alkyl; m=0, 1, 2 or 3; n=0, 1, 2 or 3; Q is pyridyl; Z is selected from aryl, heteroaryl or heterocycle; L is selected from —NR 7 CO—, —CONR 8 —, —NR 9 SO 2 —, —SO 2 NR 10 —, NR 11 COO—, —NR 12 CONR 13 —, —OCONR 14 —; wherein R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 and R 14 are independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, in which the substituent is selected from halogen, amino or hydroxyl.