Patent ID: 7244740

Claim:
A compound of formula (I): wherein: p is 0, 1 or 2; each R 1 is the same or different and is independently selected from the group consisting of halo, alkyl, Het, OR 7 , —C(O)Het, —S(O) n R 9 , —S(O) 2 NR 7 R 8 , —NR 7 R 8 , —NR 7 Ay, —NHHet, wherein when p is 1, R 1 is in the C-8 position or C-6 position, and when p is 2, one R 1 is in the C-8 position and one R 1 is in the C-6 position; each R 7 and R 8 are the same or different and are independently selected from the group consisting of H, alkyl, alkenyl, cycloalkyl, cycloalkenyl, —C(O)R 9 , —CO 2 R 9 , —C(O)NR 9 R 11 —C(NH)NR 9 R 11 , —SO 2 R 10 , —SO 2 NR 9 R 11 , —R 10 cycloalkyl, —R 10 OR 9 and —R 10 NR 9 R 11 ; each R 9 and R 11 are the same or different and are independently selected from the group consisting of H, alkyl, cycloalkyl, —R 10 cycloalkyl, —R 10 OH, —R 10 (OR 10 ) w where w is 1–10, and —R 10 NR 10 R 10 ; each R 10 is the same or different and is independently selected from the group consisting of alkyl, cycloalkyl, alkenyl, cydoalkenyl and alkynyl; Ay is aryl; Het is a 5- or 6-membered heterocyclic or heteroaryl group; R 2 is selected from the group consisting of H, alkyl and cycloalkyl; n is 0, 1 or 2; Y is N; R 3 and R 4 are the same or different and are each independently selected from the group consisting of H, halo, alkyl, alkenyl, cycloalkyl, Ay, Het, —OR 7 , —C(O)R 7 , —CO 2 R 7 , —SO 2 NHR 9 , —NR 7 R 8 , —NHHet and —NHR 10 Het; q and q′ are the same or different and are each independently selected from the group consisting of 0, 1, 2 and 3; and each R 5 and R 5′ are the same or different and are independently selected from the group consisting of halo, alkyl, alkenyl, alkynyl, cycfoalkyl, cycloalkenyl, Ay, Het, —OR 7 , —OAy, —OR 10 Ay, —OHet, —OR 10 Het, —C(O)R 9 , —C(O)Ay, —C(O)Het, —CO 2 R 9 , —C(O)NR 7 R 8 , —C(O)NR 7 Ay, —C(O)NHR 10 Het, —C(S)NR 9 R 11 , —C(NH)NR 7 R 8 , —C(NH)NR 7 Ay, —S(O) n R 9 , —S(O) 2 NR 7 R 8 , —S(O)NR 7 Ay, —NR 7 R 8 , —NR 7 Ay, —NHHet, —NHR 10 Ay, —NHR 10 Het, —R 10 cycloalkyl, —R 10 Het, —R 10 OR 9 , —R 10 (O)R 9 , —R 10 CO 2 R 8 , —R 10 (O)NR 9 R 11 , —R 10 (O)NR 7 Ay, —R 10 C(O)NHR 10 Het, —R 10 C(S)NR 9 R 11 , —R 10 C(NH)NR 9 R 11 , —R 10 SO 2 R 9 , —R 10 SO 2 NR 9 R 11 , —R 10 SO 2 NHCOR 9 , —R 10 NR 7 R 8 , —R 10 NR 7 Ay, —R 10 NHC(NH)NR 9 R 11 , cyano, nitro and azido; or two adjacent R 5 or R 5 groups together with the atoms to which they are bonded form a C 5-6 cycloalkyl or aryl; or a pharmaceutically acceptable salt thereof.