Patent ID: 7186849

Claim:
A taxane having the formula wherein R 2 is acyloxy; R 7 is R 7a COO—; R 7a is hydrocarbyl, substituted hydrocarbyl, or heterocyclo wherein said hydrocarbyl or substituted hydrocarbyl contains carbon atoms in the alpha and beta positions relative to the carbon atom of which R 7a is a substituent and wherein said substituted hydrocarbyl is substituted with a group selected from halogen, heterocyclo, alkoxy, alkenoxy, alkynoxy, aryloxy, hydroxy, protected hydroxy, acyloxy, nitro, cyano, thiol, ketals, acetals and ethers; R 9 is keto, hydroxy, or acyloxy; R 10 is hydroxy; R 14 is hydrido or hydroxy; X 3 is heterocyclo; X 5 is —COX 10 , and X 10 is alkyl, alkenyl, alkynyl or heterocyclo; or X 5 is —COOX 10 and X 10 is substituted or unsubstituted methyl, ethyl, n-propyl, iso-propyl, cyclopropyl, n-butyl, iso-butyl, sec-butyl, cyclobutyl, n-pentyl, iso-pentyl, tert-pentyl, sec-pentyl, cyclopentyl, n-hexyl, iso-hexyl, sec-hexyl, tert-hexyl, cyclohexyl, alkenyl, alkynyl or heterocyclo; and Ac is acetyl.