Patent ID: 8487093

Claim:
A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: X is: (1) CH 2 , or (2) CH 2 CH 2 ; R 1 is C(O)N(R 3 )R 4 , R 2 is SO 3 M, OSO 3 M, SO 2 NH 2 , PO 3 M, OPO 3 M, CH 2 CO 2 M, CF 2 CO 2 M, or CF 3 ; M is H or a pharmaceutically acceptable cation; R 3 is HetA; R 4 is H; or alternatively R 3 and R 4 together with the N atom to which they are both attached form heterocyclyl selected from the group consisting of: HetA is a 4- to 9-membered saturated or mono-unsaturated heterocyclic ring containing 1 or 2 N atoms; wherein the ring is optionally fused with a C 3-7 cycloalkyl; and wherein the optionally fused, saturated or mono-unsaturated heterocyclic ring is optionally substituted with 1 to 2 substituents selected from N(R A )R B and (CH 2 ) n R C ; each n is independently an integer which is 0, 1, 2, or 3; each R A is independently H or C 1-8 alkyl; each R B is independently H or C 1-8 alkyl; each R C is independently C 1-6 alkyl, OH, O—C 1-8 alkyl, halogen pyridyl, pyrrolidinyl, or piperidinyl.