Patent ID: 8017779

Claim:
A compound of formula (IIa): wherein: is a heterocyclic ring system selected from the group consisting of: wherein the heterocyclic ring system is unsubstituted or substituted by one or more substituents selected from the group consisting of: alkoxy, hydroxy, nitro, oxo, hydroxyalkyl, alkyl, phenyl optionally substituted by one or more halogens, benzyl optionally substituted by one or more halogens, —N(R 8 )-Q-R 4 , —X—N(R 8 )-Q-R 4 , —X—O-phenyl, wherein phenyl is optionally substituted by one or more substituents selected from the group consisting of alkoxy and halogen, —X-pyrrolidinyl, —X-piperidinyl, —X-morpholinyl, and —X-piperazinyl, wherein pyrrolidinyl, piperidinyl, morpholinyl, and piperazinyl are unsubstituted or substituted by one or more substituents selected from the group consisting of alkyl, hydroxy, hydroxyalkyl, acetyl, and acetamido; R 1 is selected from the group consisting of alkyl, alkoxyalkylenyl, and hydroxyalkylenyl; R 2 is selected from the group consisting of hydrogen, alkyl, alkoxyalkylenyl, and hydroxyalkylenyl; X is alkylene, R 4 is alkyl; Q is selected from the group consisting of a bond and —C(R 6 )—; R 6 is selected from the group consisting of ═O and ═S; R 8 is selected from the group consisting of hydrogen and alkyl; and R is selected from the group consisting of hydrogen, alkyl, alkoxy, trifluoromethyl, chloro, fluoro, and hydroxy; or a pharmaceutically acceptable salt thereof.