Patent ID: 8466116

Claim:
A method of inducing epithelial cell growth, comprising contacting an epithelial cell with an effective amount of a CpG oligodeoxynucleotide, wherein the CpG oligodeoxynucleotide comprises a nucleic acid sequence as set forth as: 5′ N 1 N 2 N 3 D-CpG-WN 4 N 5 N 6 3′ (SEQ ID NO: 2) wherein the central CpG motif is unmethylated, D is T, G or A, W is A or T, and N 1 , N 2 , N 3 , N 4 , N 5 , and N 6 are any nucleotides and wherein the CpG oligodeoxynucleotide is 10 to 30 nucleotides in length, thereby inducing the epithelial cell growth, wherein the epithelial cell is in a graft.