Patent ID: 6921765

Claim:
A method of treating cancer, comprising administering to a mammal in need thereof a therapeutically effective amount of a compound having the formula I wherein R 2 or R 3 are the same or different and are chosen from the group of hydrogen, C1-15 alkyl, C2-15 alkenyl, C2-15 alkynyl, C1-15 alkoxy, C1-15 alkylamino, aryl, C6-15 aryl alkyl, C1-15 alkyl carboxy, C2-15 alkyl alkyl carboxylate, C1-15 alkylthio, C1-15 alkyl hydroxy, wherein said groups optionally can be substituted with halogen or from 2-hydroxymethyl-3,3-dihydroxy-1-azabicyclo[2,2,2]octane [[and from compounds having the formula II wherein R 1 is chosen from the group of hydrogen, C1-15 alkyl, C1-15 alkenyl, C1-15 alkynyl, C1-15 alkoxy, C1-15 alkylamino, aryl, C6-15 aryl alkyl, C1-15 alkyl carboxy, C2-15 alkyl alkyl carboxylate, C1-15 alkylthio, C1-15 alkyl hydroxyl, wherein said groups optionally can be substituted with halogen, for the preparation of a pharmaceutical for the treatment of conditions caused by mutant p53 protein]].