Patent ID: 7790443

Claim:
A bioreactor comprising: (a) a first substrate having a first surface, an opposite second surface and edges; (b) a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, wherein the bottom surface is located therebetween the first surface and the second surface, and wherein the first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a chamber for receiving cells and a liquid medium; and (c) a port formed between the bottom surface and the first surface of the second substrate with a first opening and an opposite, second opening, wherein the port is in fluid communication with the chamber through the first opening to allow a, stream of substance to be introduced into the chamber through the port substantially along a first direction, wherein the second substrate further defines a third opening and an opposite fourth opening adapted for allowing a flow of liquid to be introduced into the chamber through the third opening and away from the chamber through the fourth opening substantially along a second direction, and wherein the second direction is substantially perpendicular to the first direction.