Patent ID: 6890956

Claim:
A compound of formula I: wherein n is 1 or 2; R 1 represents CF 3 or C 1-6 alkyl, C 2-6 alkenyl, C 3-9 cycloalkyl or C 3-6 cycloalkylC 1-6 alkyl, any of which may bear up to 2 substituents selected from halogen, CN, CF 3 , OR 3 , COR 3 , CO 2 R 3 , OCOR 4 , SO 2 R 4 , N(R 5 ) 2 , and CON(R 5 ) 2 , or R 1 represents aryl, arylC 1-6 alkyl, C-heterocyclyl or C-heterocyclylC 1-6 alkyl; R 2 represents H or C 1-4 alkyl; R 3 represents H, C 1-4 alkyl, phenyl or heteroaryl; R 4 represents C 1-4 alkyl, phenyl or heteroaryl; R 5 represents H or C 1-4 alkyl, or two R 5 groups together with a nitrogen atom to which they are mutually attached complete an azetidine, pyrrolidine, piperidine, morpholine, thiomorpholine or thiomorpholine-1,1-dioxide ring; Ar 1 and Ar 2 independently represent phenyl or heteroaryl, either of which bears 0-3 substituents independently selected from halogen, CN, NO 2 , CF 3 , CHF 2 , OH, OCF 3 , CHO, CH═NOH, C 1-4 alkoxy, C 1-4 alkoxycarbonyl, C 2-6 acyl, C 2-6 alkenyl and C 1-4 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; aryl at every occurrence thereof refers to phenyl or heteroaryl which optionally bear up to 3 substituents selected from halogen, CN, NO 2 , CF 3 , OCF 3 , OR 3 , COR 3 , CO 2 R 3 , OCOR 4 , N(R 5 ) 2 , CON(R 5 ) 2 and optionally-substituted C 1-6 alkyl, C 1-6 alkoxy, C 2-6 alkenyl or C 2-6 alkenyloxy wherein the substituent is selected from halogen, CN, CF 3 , phenyl, OR 3 , CO 2 R 3 , OCOR 4 , N(R 5 ) 2 and CON(R 5 ) 2 ; and C-heterocyclyl and N-heterocyclyl at every occurrence thereof refer respectively to a heterocyclic ring system bonded through carbon or nitrogen, said ring system being non-aromatic and comprising up to 10 atoms, at least one of which is O, N or S, and optionally bearing up to 3 substituents selected from oxo, halogen, CN, NO 2 , CF 3 , OCF 3 , OR 3 , COR 3 , CO 2 R 3 , OCOR 4 , OSO 2 R 4 , N(R 5 ) 2 , CON(R 5 ) 2 and optionally-substituted phenyl, C 1-6 alkyl, C 1-6 alkoxy, C 2-6 alkenyl or C 2-6 alkenyloxy wherein the substituent is selected from halogen, CN, CF 3 , OR 3 , CO 2 R 3 , OCOR 4 , N(R 5 ) 2 and CON(R 5 ) 2 ; or a pharmaceutically acceptable salt thereof.