Patent ID: 7183303

Claim:
A compound of formula I: wherein the moiety X—Ar is attached at one of the positions indicated by an asterisk; X is a bivalent residue of a heteroaryl ring consisting of 5 ring atoms of which two or three are selected from O, N and S, optionally bearing a hydrocarbon substituent comprising 1–5 carbon atoms which is optionally substituted with up to 3 halogen atoms; Ar is phenyl or 6-membered heteroaryl, either of which bears 0–3 substituents independently selected from halogen, CF 3 , CHF 2 , CH 2 F, NO 2 , CN, OCF 3 , C 1-6 alkyl and C 1-6 alkoxy; A is (CH 2 )n where n is 0; bond a is single or double; R 1 is H or C 1-6 alkyl, C 2-6 alkenyl, or C 2-6 alkynyl, any of which optionally is substituted with up to 5 fluorine atoms; and R 2 is H or together with R 1 completes a fused benzene ring which is optionally substituted with up to 3 halogen atoms or C 1-4 alkyl groups; or a pharmaceutically acceptable salt thereof.