Patent ID: 7479478

Claim:
A method for treating a mammalian subject having a condition characterized by a decrease in bone mass, said method comprising administering to said subject an effective bone mass-increasing amount of a biologically active peptide consisting essentially of the formula: (a) X 01 ValSerGluIleGlnLeuMetHisAsnLeuGly LysHisLeuAsnSerMetX 02 ArgValGluTrpLeuArgLysLysLeu (SEQ ID NO:1); (b) fragments thereof containing amino acids 1-24, 1-25, 1-26, or 1-27; (c) pharmaceutically acceptable salts thereof; or (d) N- or C-terminal chemical derivatives thereof; wherein: X 01 is Ser, Ala or Gly; and X 02 is Glu or Arg, provided that said peptide is not hPTH(1-26)NH 2 , hPTH(1-27)NH 2 or hPTH(1-28)NH 2 ; and a pharmaceutically acceptable carrier.