Patent ID: 7996158

Claim:
A method, comprising: initiating, using one or more processors, a calibration routine associated with an in vivo analyte sensor based on a current calibration parameter, the current calibration parameter including a current sensitivity value determined from a current reference analyte measurement and one or more signals from the in vivo analyte sensor; retrieving, from a memory, a prior calibration parameter including a previously determined sensitivity value from a prior calibration routine to calibrate the analyte sensor based on a reference analyte measurement and one or more previously obtained signals from the in vivo analyte sensor; comparing, using the one or more processors, the current calibration parameter and the retrieved prior calibration parameter; and determining, using the one or more processors, a stability status associated with the analyte sensor based at least in part on comparing the current calibration parameter and the retrieved prior calibration parameter; wherein when the stability status indicates that the in vivo analyte sensor is stable, completing the calibration routine including determining a composite sensitivity value based on the current calibration parameter and the prior calibration parameter, and when the stability status indicates that the in vivo analyte sensor is not stable, re-initiating the calibration routine.