Patent ID: 7153930

Claim:
A method of administering a pharmaceutical composition, comprising i) providing a pharmaceutical composition comprising an amide of a bile acid/salt of formula (II) wherein R 1 to R 5 are independently selected from OH, H or C 1-6 alkyl; and A is —R 6 —CO—X—Y wherein R 6 is C 2 to C 6 branched or linear alkylene; X is at least one peptide chain of at least 4 amino acids in length which may be linear, branched or comprise two or more cross-linked polypeptide chains and is selected from insulin, calcitonin, secretin, gastrin, gastrin tetrapeptide, gastrin decapeptide, 34 mer-gastrin, and active fragments thereof; and Y is OH, NH 2 , or a C 1 –C 6 ester group bonded to the terminal carboxy of the polypeptide chain, and ii) orally administering said pharmaceutical composition to a subject in need thereof.