Patent ID: 7846657

Claim:
A pair of oligonucleotide probes (K) comprising: (a) a first oligonucleotide probe (P 1 ) that comprises (i) a first clamp segment (C 1 ), that is capable of hybridizing to a second clamp segment (C 2 ) of a second oligonucleotide probe (P 2 ), and (ii) a first target segment (T 1 ) at its 3’ end that is capable of hybridizing to a first segment (S 1 ) of a target DNA sequence (D) to be detected; (b) a second oligonucleotide probe (P 2 ) that comprises (i) a second clamp segment (C 2 ), that is capable of hybridizing to C 1 , and (ii) a second target segment (T 2 ) at it's 5’ end that is capable of hybridizing to a second segment (S 2 ) of D wherein S 1 and S 2 are located essentially adjacent to one another in D, and wherein the 5’ end of S 1 is adjacent to the 3’ end of S 2 .