Patent ID: 8242109

Claim:
A method of treating a disorder selected from the group consisting of graft versus host disease, psoriasis, and leukemia, comprising administering an effective amount of a benzodiazepine compound of Formula I or II to a subject in need thereof to treat said disorder, wherein Formula I is represented by: or a pharmaceutically acceptable salt thereof; and including both R and S enantiomeric forms and racemic mixtures thereof; wherein: X is selected from the group consisting of halogen, alkyl, and an alkyl group substituted by one or more substituents selected from the group consisting of halogen, hydroxyl, alkylcarbonyloxy, alkylaminocarbonyl, alkoxyl, cyano, amino, and acylamino; and R 2 is selected from the group consisting of hydrogen and a linear or branched alkyl; and wherein Formula II is represented by: or a pharmaceutically acceptable salt thereof; and including both R and S enantiomeric forms and racemic mixtures thereof; wherein: X is selected from the group consisting of halogen, alkyl, and an alkyl group substituted by one or more substituents selected from the group consisting of halogen, hydroxyl, alkylcarbonyloxy, alkylaminocarbonyl, alkoxyl, cyano, amino, and acylamino; R 2 is selected from the group consisting of hydrogen and a linear or branched alkyl; and R 5 is alkyl optionally substituted by one or more substituents selected from the group consisting of halogen, hydroxyl, alkoxyl, cyano, and amino.