Patent ID: 8716221

Claim:
A modified exendin or pharmaceutically acceptable salt thereof, comprising an amino acid sequence having at least 90% sequence identity to SEQ ID No. 17, wherein the amino acid in the position of said amino acid sequence corresponding to position 2 of SEQ ID No. 17 is D-Ala, wherein one or both amino acids in the positions of said amino acid sequence corresponding to positions 14 and 28 of SEQ ID No. 17 are substituted to be other than Met in position 14 and/or Asn at position 28, wherein each said position refers to the position as numbered in SEQ ID No. 17, and wherein the modified exendin or salt thereof has a higher stability than the non-modified exendin of SEQ ID No. 4, and wherein the amino acid sequence is SEQ ID No. 94.