Patent ID: 7776897

Claim:
A compound represented by the formula (I) or a salt thereof: [Chem 14] wherein the symbols have the following meanings: R 1 : —N(R 0 )S(O) 2 -lower alkyl, —N(R 0 )-optionally substituted lower alkyl, —X—R 4 , or each optionally substituted cycloalkyl or heterocyclic group; R 4 : each optionally substituted aryl, cycloalkyl or heterocyclic group; X: —O—, —N(R 5 )—, —C(O)—, —S—, —S(O)—, —S(O) 2 —, —C(O)N(R 0 )—, —N(R 0 )C(O)—, —N(R 0 )C(O)N(R 0 )—, —N(R 6 )S(O) 2 —, —S(O) 2 N(R 6 )—, —C(O)-lower alkylene, lower alkylene-C(O)—, —N(R 5 )-lower alkylene, lower alkylene-N(R 5 )—, or each optionally substituted lower alkylene, lower alkenylene or lower alkynylene; R 5 : —H, lower alkyl, lower alkylene-CO 2 R 0 , lower alkylene-OR 0 , —C(O)R 0 or —C(O)-aryl, —S(O) 2 R 0 , —S(O) 2 -aryl or aryl; R 6 : —H, lower alkyl, —C(O)R 0 or —C(O)-aryl; R 0 : the same or different from each other, —H or lower alkyl; R 2 : —R 7 ; R 3 : —R 7 , —OR 7 , —NHR 7 , —N(R 7 )S(O) 2 -lower alkyl, —N(R 7 ) 2 or —S-lower alkylene-(optionally substituted aryl); or R 2 and R 3 are combined together with the nitrogen atom and the carbon atom to which they are attached to form a nitrogen-containing heterocycle; provided that a ring formed by condensing the triazole ring with the nitrogen-containing heterocycle, which is formed by combining R 2 and R 3 together with the nitrogen atom and the carbon atom to which they are attached, is not pyrazolo[5,1-c][1,2,4]triazole nor [1,2,4]triazolo[3,4-b][1,3,4]thiadiazine; R 7 : the same or different from each other, each optionally substituted lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl or heterocyclic group; A and B: the same or different from each other, halogen, —R 7 , —OH, —OR 7 , —NH 2 , —NHR 7 , —N(R 7 ) 2 , —SR 7 , —S(O)R 7 or —S(O) 2 R 7 ; or A and B may be combined together with the carbon atom to which they are attached to form each optionally substituted cycloalkyl ring or non-aromatic heterocycle; provided that: 1-(1-{5-[(4-chlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl}-1-methylethyl)-1H-1,2,4-triazole, 1-{1-methyl-1-[5-(4-methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]ethyl}-1H-1,2,3-benzotriazole, N-[2-(4-chlorophenyl)ethyl]N-methyl-1-(5-methyl-4-phenyl-4H-1,2,4-triazol-3-yl)cyclohex-2-en-1-amine, 3-(2,4-dichlorophenyl)-4-methyl-5-[1-(2-thienyl)cyclopropyl]-4H-1,2,4-triazole, 3-chloro-4-{4-methyl-5-[1-(2-thienyl)cyclopropyl]-4H-1,2,4-triazol-3-yl}benzamide, and N-(3 -chloro-4- {4-methyl-5-[1-(2-thienyl)cyclopropyl]-4H-1,2,4-triazol-3-y1}phenyl)acetamide are excluded.