Patent ID: 7351790

Claim:
A compound of general formula (I) having an affinity for the integrin receptors, (I) wherein G represents glycine, and D represents aspartic acid, and R 1 represents —(CH 2 ) n — or —(CH 2 ) n —C 6 H 4 — wherein n represents a positive integer 1 to 3, and X 1 represents a bond or 1 to 2 amino acid residues wherein each amino acid residue independently optionally can be derivatized with a carbohydrate, PEG-containing moiety or alkyl chain in order to modify the pharmacokinetics or blood clearance rates of said agents, X 2 and X 4 represent independently an amino acid residue capable of forming a disulfide bond, X 3 represents arginine, N-methylarginine or an arginine mimetic, X 5 represents a hydrophobic amino acid and, X 6 represents a thiol-containing amino acid residue, and X6 forms a thioether bridge linked to R1, and k represents a positive integer 1 to 10, and X 7 represents a linker (L) moiety comprising a PEG spacer, or X 7 is absent and X 8 represents a reporter (R) moiety, or is —NH 2 or is absent, and pharmaceutical acceptable salts thereof.