Patent ID: 8776786

Claim:
A pulmonary drug delivery system capable of nebulizing a drug composition comprising a water-insoluble or substantially water-insoluble drug and a fatty acid or lipid, the system comprising: a carrier gas reservoir; a drug reservoir comprising a flexible bladder that is disposed within the carrier gas reservoir and that is able to be pressurized by gas within the carrier gas reservoir; a face mask; and a nebulizing nozzle in fluid communication with face mask, the drug reservoir and the carrier gas reservoir, wherein the nebulizing nozzle comprises an outer carrier gas delivery tube spaced apart from and disposed around at least one inner drug delivery tube and wherein the outer carrier gas delivery tube and the at least one inner drug delivery tube(s) share a longitudinal axis and are together dimensioned and disposed such that expulsion of a carrier gas through the outer carrier gas delivery tube forms an outer surrounding stream of carrier gas that carries an inner flow of fluid from the drug reservoir in a center of carrier gas flow exiting the nebulizing nozzle and thereby produces aerosol drug containing droplets having a particle size ranging from about 2 μm to about 12 μm in median mass aerodynamic size that are delivered to a patient via a mouth and/or nose of the patient.