Patent ID: 7186841

Claim:
A compound having a formula: or a pharmaceutically acceptable salt thereof, wherein W is N; X id CH; R 4 is selected from the group consisting of H, (C 1 –C 6 )alkyl, (C 3 –C 6 )cycloalkyl, (C 4 –C 7 )cycloalkyl-alkyl, (C 2 –C 6 )alkenyl and (C 2 –C 6 )alkynyl; A is a substituted or unsubstituted 6-membered carbocyclic or heterocyclic aromatic ring system, wherein the heterocyclic aromatic ring system contains 1–2 N atoms; and B is selected from the group consisting of 1-methylimidazol-5-yl, 1-(trifluoromethyl)imidazol-5-yl, 5-methylimidazol-1-yl, 5-(trifluoromethyl)imidazol-1-yl, thiazol-5-yl, imidazol-1-yl, 1-methyl-1,3,4-triazolyl, and 4-methyl-1,2,4-triazol-3-yl, wherein the B ring is substituted or unsubstituted, and the substituents on B ring, if present, are selected from a group consisting of halogen, CF 3 , CF 3 O, (C 1 –C 6 )alkyl, perfluoro(C 1 –C 6 )alkyl, (C 2 –C 6 )alkenyl, (C 2 –C 6 )alkynyl, (C 1 –C 6 )heteroalkyl, (C 1 –C 6 )alkoxy, (C 1 –C 6 )thioalkoxy, amino, (C 1 –C 6 )alkylamino, di(C 1 –C 6 )alkylamino, (C 3 –C 10 )cycloalkyl, (C 4 –C 10 )cycloalkyl-alkyl, (C 3 –C 10 )cycloheteroalkyl, cyano, nitro, sulfonamido, (C 1 –C 6 )acyl, (C 1 –C 6 )acylamino, (C 2 –C 6 )alkoxycarbonyl, (C 2 –C 6 )alkoxycarbonyl(C 1 –C 6 )alkyl, carboxamido and (C 1 –C 6 )heteroalkoxy.