Patent ID: 8664003

Claim:
A method for clathrating a biological material in a hole pattern of a film formed on a substrate, the film and substrate forming a chip, the method comprising: controlling film temperature of the chip to a temperature at which a diameter of a hole of the hole pattern becomes a size capable of housing the biological material; housing the biological material in the hole of the hole pattern; and controlling the film temperature of the chip to a temperature at which the diameter of the hole having housed the biological material clathrates the biological material, wherein: the film comprises a crosslinked product of a temperature-responsive N-alkyl (meth)acrylamide copolymer and a crosslinker, the N-alkyl (meth)acrylamide copolymer having a weight average molecular weight of 500 to 5,000,000 and a recurring unit represented by general formula (1): wherein R 1 and R 2 may be the same as or different from each other and represent a hydrogen atom or an (1-4C) alkyl group; R 3 represents a hydrogen atom or a methyl group; R 4 represents a hydrocarbon structure having a functional group crosslinkable with the crosslinker; and x and y are any numbers satisfying numerical formulae: x+y=1, 0.6<x≦0.95, and 0.05≦y<0.4.