Patent ID: 7208503

Claim:
A compound of formula (I), the N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein X is CH; R 1 is hydrogen, C 1-6 alkyl, C 1-6 alkyloxy, C 1-6 alkylthio, amino, mono- or di(C 1-6 alkyl)amino, Ar 1 , Ar 1 NH—, C 3-6 cycloalkyl, hydroxymethyl or benzyloxymethyl; R 2 is hydrogen, C 1-6 alkyl, amino, aminocarbonyl, mono- or di(C 1-6 alkyl)amino, C 1-6 alkyloxycarbonyl, C 1-6 alkylcarbonylamino, hydroxy or C 1-6 alkyloxy; R 3 , R 4 and R 5 are each independently selected from hydrogen, halo, C 1-6 alkyl, C 1-6 alkyloxy, trifluoromethyl, nitro, amino, cyano, azido, C 1-6 alkyloxyC 1-6 alkyl, C 1-6 alkylthio, C 1-6 alkyloxycarbonyl or Het 1 ; is Het 2 ; Ar 1 is phenyl; phenyl substituted with 1, 2 or 3 substituents each independently selected from halo, C 1-6 alkyl, C 1-6 alkyloxy, trihalomethyl, amino or nitro; Het 1 is a monocyclic heterocycle selected from oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thiadiazolyl or oxazolinyl; and each monocyclic heterocycle may optionally be substituted on a carbon atom with C 1-4 alkyl; and Het 2 is a monocyclic heterocycle selected from pyridinyl; and said monocyclic heterocycle may optionally be substituted on a carbon atom with 1 or 2 substituents each independently selected from halo, C 1-4 alkyl, C 1-4 alkyloxy, nitro or trifluoromethyl.