Patent ID: 8822542

Claim:
A method of treating oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or a salicylamine compound wherein the compound is selected from the formula: wherein: R is N or C; R 2 is independently H, substituted or unsubstituted alkyl, alkoxy, alkoxyalkyl, alkylalkoxyalkyl, alkylaminoalkyl; R 3 is H, halogen, alkoxy, hydroxyl, nitro; R 4 is H, substituted or unsubstituted alkyl, carboxyl; provided that when R is N, the ortho R 2 is CH 3 and R 4 is H, then the meta R 2 cannot be hydroxymethyl; or a pharmaceutically acceptable salt thereof.