Patent ID: 8778340

Claim:
A method of treating a patient diagnosed with recurrent platinum-sensitive advanced epithelial ovarian, fallopian tube or primary peritoneal cancer, comprising subjecting the patient to a treatment regimen combining carboplatin and gemcitabine with the concurrent administration of 15 mg/kg of an anti-VEGF antibody having a heavy chain variable region comprising the following amino acid sequence: (SEQ ID NO. 1) EVQLVESGGG LVQPGGSLRL SCAASGYTFT NYGMNWVRQA PGKGLEWVGW INTYTGEPTY AADFKRRFTF SLDTSKSTAY LQMNSLRAED TAVYYCAKYP HYYGSSHWYF DVWGQGTLVT VSS and a light chain variable region comprising the following amino acid sequence: (SEQ ID NO. 2) DIQMTQSPSS LSASVGDRVT ITCSASQDIS NYLNWYQQKP GKAPKVLIYF TSSLHSGVPS RFSGSGSGTD FTLTISSLQP EDFATYYCQQ YSTVPWTFGQ GTKVEIKR followed by anti-VEGF antibody maintenance therapy, and wherein the treatment regimen effectively extends the progression free survival of the patient.