Patent ID: 8802716

Claim:
A compound of formula (5) or a pharmaceutically acceptable salt thereof where A 1 is H, or lower alkyl, or A 1 and R 1b together form a ring of 3-5 atoms; R 1a is H; R 1b is lower alkyl, or together with A 1 forms a ring of 3 to 5 atoms; Y is an alkyl group, an alkynyl group, a cycloalkyl group of 3 to 7 carbon atoms, optionally substituted versions of these groups, or Y together with Z 1a , Z 1b , or R 10 forms a carbocyclic ring, or a heterocyclic ring containing 1 to 5 heteroatoms, where Y is linked to Z 1a , Z 1b , or R 10 ; Z 1a and Z 1b are independently an H, hydroxy, amino, alkylamino, diakylamino, alkoxy, aryloxy, or heteroaryloxy; or Z 1a , Z 1b , together with Y or R 10 form a carbocyclic ring, or a heterocyclic ring containing 1 to 5 heteroatoms, where Z 1a or Z 1b , is linked to Y or R 10 ; M is an optionally-substituted alkylene of 1 to 5 carbon atoms; G is a bond, a heteroatom, —(C═O)—; —NR 18 —; —NCOR 18 —; or —NS(O) x R 18 — where x=0, 1, or 2, and R 18 is lower alkyl, or an optionally-substituted lower alkyl; and R 10 is heteroaryl.