Patent ID: 7556066

Claim:
A method comprising the following steps: providing a plurality of devices, wherein each device includes a penetrable and thermally resealable portion, and a sealed empty chamber in fluid communication with the penetrable and thermally resealable portion; sterilizing the plurality of sealed, empty devices by subjecting them to radiation capable of penetrating through the penetrable and thermally resealable portions and into the chambers; transporting the plurality of devices with sterilized internal chambers on a conveyor; conveying the devices through a sterilizing station and sterilizing at least an external surface of the penetrable and thermally resealable portions of the devices; introducing at least one injection member through the penetrable and thermally resealable portions of the devices; introducing through the at least one injection member a sterile substance into the sterile chambers of the devices; withdrawing the at least one injection member from the penetrable and thermally resealable portions; and transmitting radiation onto the penetrated surfaces of the penetrable and thermally resealable portions of the devices and, in turn, resealing the penetrable and thermally resealable portions and sealing the sterile substance within the devices.