Patent ID: 8658358

Claim:
A method for determining whether a subject suffers from or is predisposed to suffer from congenital long QT syndrome (LQTS) comprising analyzing a biological sample from a subject for the allele present at KCNQ1 mutations 1075 C>T, 190 — 210del (in which nucleotides 80718 to 80738 of SEQ ID NO: 1 are deleted), 862 — 880del (in which nucleotides 208341 to 208359 of SEQ ID NO: 1 are deleted), 1265delA, and 1338 C>G, detecting in the biological sample any one or more of the KCNQ1 mutations 1075 C>T, 190 — 210del, 862 — 880del, 1265delA, and 1338 C>G, and determining that the subject suffers from or is predisposed to suffer from LQTS when any one or more of the KCNQ1 mutations 1075 C>T, 190 — 210del, 862 — 880del, 1265delA, and 1338 C>G is present in the biological sample.