Patent ID: 7872010

Claim:
A compound of the formula (I): Z—Ar 1 -Ar 2 (I) wherein: Z is a diazabicyclic amine of formula: Ar 1 is a pyridine ring of formula: wherein, only one of X 1 , X 2 , X 3 , and X 4 is N and the remaining are —CR 3 ; Ar 2 is selected from the group consisting of 5- or 6-membered heteroaryl, bicyclic heteroaryl, 3,4-(methylenedioxy) phenyl, carbazolyl, tetrahydrocarbazolyl, naphthyl, and phenyl, substituted with 0, 1, 2, or 3 substituents selected from the group consisting of alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxysulfonyl, alkyl, alkylcarbonyl, arylcarbonyl, alkylcarbonyloxy, alkylsulfonyl, alkylthio, alkynyl, carboxy, cyano, formyl, haloalkoxy, haloalkyl, halogen, hydroxy, hydroxyalkyl, mercapto, nitro, —NR A R B , (NR A R B )alkyl, (NR A R B )carbonyl, (NR A R B )sulfonyl, and phenyl; l, m, o, and p are each independently 0, 1, or 2, and n is 0, provided that the sum total of l, m, n, o, and p is 3, 4, or 5, and further provided that the sum of l and o is at least 1 and the sum of m and p is at least 1; R 1 is selected from the group consisting of hydrogen, alkenyl, alkyl alkoxycarbonyl, arylalkyl, and heteroarylalkyl; R 2 at each occurrence is independently selected from the group consisting of hydrogen, alkoxycarbonyl, and alkyl; R 3 at each occurrence is independently selected from the group consisting of hydrogen, alkoxy, alkyl, cyano, and hydroxy; R A and R B are each independently selected from the group consisting of hydrogen, alkyl, alkylcarbonyl, alkylsulfonyl, arylcarbonyl, formyl and (NR C R D )sulfonyl; and R C and R D are each independently selected from the group consisting of hydrogen and alkyl; or a pharmaceutically acceptable salt thereof.