Patent ID: 8679531

Claim:
A vesicle composition, comprising: (A) a first liposome composition, comprising: (1) a first phospholipid; (2) cholesterol; and (3) a phospholipid-polyethylene glycol-boronic acid derivative conjugate, comprising: wherein n=30-60, and wherein the first liposome composition encapsulates a first therapeutic compound; and (B) a second liposome composition, comprising: (1) a second phospholipid; (2) cholesterol; and (3) a phospholipid-polyethylene glycol-glycosyl conjugate comprising a glycosyl moiety comprising a glucosyl moiety, a galactosyl moiety, or a mannopyranosidyl moiety, wherein: the second liposome composition encapsulates a second therapeutic compound; and the first liposome composition is cross-linked to the second liposome composition.