Patent ID: 7364899

Claim:
A device for monitoring haptotaxis including a housing comprising: a support member; a top member, the top member mounted to the support member wherein the support member and the top member are configured such that they together define at least one discrete chamber, the at least one discrete chamber including: a first well region including at least one first well, the at least one first well configured to receive a test agent therein, the at least one first well including a first plurality of biomolecules immobilized therein; a second well region including at least one second well, the at least one second well configured to receive a sample comprising cells therein and further being horizontally offset with respect to the first well region in a test orientation of the device; and a channel region including only one channel connecting the first well region and the second well region, the one channel including a second plurality of biomolecules immobilized therein, the concentration of the first plurality of biomolecules in the first well being greater than the concentration of the second plurality of biomolecules in the one channel, and the concentration decreasing from the first well region towards the second well region forming a surface concentration gradient of the first and second plurality of immobilized biomolecules, wherein the first plurality of biomolecules and the second plurality of biomolecules are of the same type.