Patent ID: 6984486

Claim:
A soluble peptide made by solid phase synthesis comprising all or a fragment or variant of a regulatory virus protein R (Vpr) of the human immunodeficiency virus type 1(HIV-1) (SEQ ID NO: 1), wherein the fragment or variant thereof consists of a peptide selected from the group consisting of: (a) a 20 amino acid Vpr protein (sVpr 1-20 or sVpr 21-40 ; SEQ ID NO: 8 and 9, respectively); (b) a 47 amino acid N-terminal peptide (sVpr 1-47 ; SEQ ID NO: 2); (c) a 49 amino acid long C-terminal peptide (sVpr 48-96 ; SEQ ID NO: 3); (d) sVpr 11-25 (SEQ ID NO: 4); or (e) sVpr 46-60 (SEQ ID NO: 6).