Patent ID: 6939569

Claim:
An implantable anti-infective medical device selected from the group consisting of catheters, prostheses, shunts, stents, and leadwires, said device comprising a solid polymeric matrix selected from the group selected from a two component elastomer formulation, room temperature vulcanization elastomers, thermoplastic polymers, and hydrogels, containing within the matrix solid particles of an oxidant-producing component comprising a reducing agent, an oxidizing agent consisting of anhydrous alkali iodine oxide salts, inorganic and organic peracids, iodine pentoxide, an oxidase enzyme, and combinations thereof, that, when wetted, causes the formation of an oxidant and sustained release of the thus-formed oxidant into and about the polymeric matrix so that the matrix serves as an anti-infective reservoir; wherein the oxidant is iodine generated at a quantity sufficient so that free-iodine concentration near a surface of the device should reach a level of at least 5 ppm; wherein the polymeric matrix is formed from room temperature vulcanization elastomers when the oxidizing agent is selected to be the oxidase enzyme; wherein the device further comprises an iodide salt when the oxidizing agent is inorganic and organic peracids or the oxidase enzyme.