Patent ID: 8835407

Claim:
A method of administering prasugrel and its pharmaceutically acceptable salts to a subject suffering from an acute coronary syndrome, comprising: identifying a subject suffering from an acute coronary syndrome; administering to the subject a loading dose of a pharmaceutical composition comprising: prasugrel, and a cyclodextrin derivative of formula I: wherein: n is 4, 5 or 6, and R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are independently selected from: —OH, a straight-chain or branched —O—(C 1 -C 8 -(alkylene))-SO 3 − group, an optionally substituted straight-chain, branched, or cyclic —O—(C 1 -C 10 ) group, an optionally substituted straight-chain, branched, or cyclic —S—(C 1 -C 10 ) group, and a saccharide, and wherein the cyclodextrin derivative is present in a concentration of at least 100:1 by weight relative to the prasugrel; and subsequently administering to the subject a maintenance dose of said pharmaceutical composition, wherein the maintenance dose comprises a lower amount of prasugrel than the loading dose.