Patent ID: 8728486

Claim:
An imidazoquinoline derived compound of Formula I or pharmaceutically acceptable salt thereof, wherein Formula I has the structure: wherein, R is selected from the group consisting of: —NH(R 5 ) and isothiocyanate; R 5 is selected from the group consisting of hydrogen, acetyl, —CO-tert-Bu (-Boc), —CO—(CH 2 ) x —R 6 , C 1 -C 16 alkyl, —CO-4-(phenylboronic acid), —C(S)—NH—(CH 2 ) x —NH—(CH 2 ) x —NH—(CH 2 ) x —NH 2 , a reporter moiety, a tissue-specific moiety, a peptide antigen moiety, a protein antigen moiety, a polysaccharide antigen moiety, and a TLR2 agonist moiety; R 6 is selected from the group consisting of hydrogen, alkyne, azido, carboxylic acid, and —CONH—(CH 2 ) x —O—(CH 2 ) x —O—(CH 2 ) x —O—(CH 2 ) x —R 7 ; R 7 is selected from the group consisting of amino, isothiocyanate, and —NH—CO—(CH 2 ) x —CO 2 H; R 8 is selected from a peptide antigen moiety or a protein antigen moiety; and x is any integer from 1 to 10.