Patent ID: 7750038

Claim:
A compound of the structure: wherein: n is 1; Z is CR 4 R 5 ; R 1 is selected from the group consisting of C 1 to C 6 alkyl, C 3 to C 8 cycloalkyl, substituted C 1 to C 6 alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, C 3 to C 6 alkenyl, C 3 to C 6 substituted alkenyl, C 3 to C 6 alkynyl, and C 3 to C 6 substituted alkynyl; R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of H, halogen, CN, C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, —(CH m X r ) z CH p X q , C 3 to C 6 cycloalkyl, O—C 1 to C 6 alkyl, O—C 1 to C 6 substituted alkyl, —O—(CH m X r ) z CH p X q , aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, and substituted heterocycle; or R 2 and R 4 ; or R 2 and R 5 ; or R 3 and R 4 ; or R 3 and R 5 are joined to form a carbocyclic or heterocyclic ring containing from 3 to 8 atoms; R 6 , R 7 and R 8 are independently selected from the group consisting of H, halogen, CN, C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, (CH m X r ) z CH p X q , C 3 to C 6 cycloalkyl, O—C 1 to C 6 alkyl, O—C 1 to C 6 substituted alkyl, O—(CH m X r ) z CH p X q , aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, and substituted heterocycle; X is halogen; m and r are, independently, 0 to 2, provided that m+r=2; p and q are, independently, 0 to 3, provided that p+q=3; z is 0 to 10; and R 9 is selected from the group consisting of H, C 1 to C 6 alkyl, C(O)O—C 1 to C 6 alkyl, C 2 to C 6 alkenyl, C 2 to C 6 alkynyl, substituted C 1 to C 6 alkyl, C 3 to C 6 cycloalkyl, and substituted C 3 to C 6 cycloalkyl; or a pharmaceutically acceptable salt or tautomer thereof.