Patent ID: 8829190

Claim:
A compound according to formula I, wherein R 1 is halogen, or R 1 is alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, cycloalkyl, alkoxycarbonyl, aryl, each being optionally substituted with one or more substituents selected from R 3 ; R 2 is substituted cycloalkyl being substituted with one or more substituents selected from R 4 ; R 3 is hydrogen, aryl, heteroaryl, oxo, halogen, hydroxy, alkyl, cycloalkyl, alkoxy, or amino; R 4 is halogen, oxo, hydroxy, carboxy, alkyl, alkoxy, amino, —NR a R b or —C(O)—NR a R b , wherein each of R a and R b is independently hydrogen, hydroxy, alkyl, alkenyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, alkylaryl or alkylheteroaryl, or R a and R b together with the nitrogen atom to which they are attached form a heterocycloalkyl ring, each being optionally substituted with one or more substituents selected from R 3 , or R 4 is aryl substituted with one or more substituents selected from R 5 ; X and Y are either C and N or N and C, respectively; Z is —CH 2 —; A is aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocycloalkyl or heterocycloalkenyl, each being optionally substituted with one or more substituents selected from the group consisting of R 5 ; R 5 is hydrogen, halogen, oxo, alkyl or alkoxy; and pharmaceutically acceptable salts and N-oxides thereof.