Patent ID: 7957913

Claim:
A method of determining whether a therapeutic is useful for treating a condition or disease comprising: (a) screening a subject's genome with PCR, array comparative genomic hybridization, sequencing, SNP genotyping, or fluorescence in situ hybridization to provide information on one or more copy number variants; (b) comparing via a computer, information of said one or more copy number variants from the genome of said subject to a compilation of data comprising frequencies of copy number variants in at least 100 subjects; and (c) determining a statistical significance of said one or more copy number variants from the comparison of step (b) to the success of said therapeutic to treat a condition or disease, the failure of said therapeutic to treat a condition or disease, a beneficial effect of said therapeutic in said subject or an adverse effect of said therapeutic in said subject, or determining whether a copy number variant is present in said subject but not present in said compilation of data from the comparison of step (b), wherein said computer comprises computer executable logic that provides instructions for executing said comparison.