Patent ID: 7951826

Claim:
A compound structurally represented by Formula I or a pharmaceutically acceptable salt thereof wherein: Y independently represents carbon or nitrogen, R1 is independently —(C 1 -C 7 ) alkyl (optionally substituted with 1 to 4 halogens, or wherein R1 is —CH 3 , then optionally substituted with 1 to 3 halogens), provided that when Y is carbon, then R1 is not —(CH 2 ) 3 —Cl, —(C 3 -C 8 ) cycloalkyl (optionally substituted with 1 to 3 halogens), —(C 1 -C 7 ) alkyl-O—R3, —(C 1 -C 7 ) alkyl-S(O) 2 —(C 1 -C 3 ) alkyl, —(C 1 -C 7 ) alkyl-C(O)—O—R3, —(C 1 -C 7 ) alkyl-S(O) 2 -phenyl(R2)(R3)(R4), —(C 1 -C 7 ) alkyl-S—(C 1 -C 7 ) alkyl, —(C 1 -C 7 ) alkyl-(C 3 -C 8 ) cycloalkyl, —(C 1 -C 7 ) alkyl-O-phenyl(R2)(R3)(R4), —(C 2 -C 7 ) alkyl-phenyl(R2)(R3)(R4), —(C 2 -C 7 ) alkenyl, —(C 3 -C 8 ) cycloalkenyl, —(C 2 -C 7 ) alkenyl-O—R3, —(C 2 -C 7 ) alkenyl-S(O) 2 —(C 1 -C 3 ) alkyl, —(C 2 -C 7 ) alkenyl-C(O)—O—R3, —(C 2 -C 7 ) alkenyl-S(O) 2 -phenyl(R2)(R3)(R4), —(C 2 -C 7 ) alkenyl-S—(C 1 -C 7 ) alkyl, —(C 2 -C 7 ) alkenyl-(C 3 -C 8 ) cycloalkyl, —(C 2 -C 7 ) alkenyl-O-phenyl(R2)(R3)(R4), —(C 2 -C 7 ) alkenyl-phenyl(R2)(R3)(R4), or -phenyl optionally substituted once or twice with R2, and independently optionally substituted once or twice with R3; R2 is independently at each occurrence —H, -halogen, —(C 1 -C 7 ) alkyl (optionally substituted with 1 to 3 halogens), —C(O)R7, —C(O)OR7, —C(O)(C 3 -C 8 )cycloalkyl, —OCF 3 , —OR7, —SR7, —SO 2 R7, —SO 2 CF 3 , or —S(O)R7; R3 is independently at each occurrence —H, or —(C 1 -C 4 ) alkyl (optionally substituted with 1 to 3 halogens); R4 and R5 are independently at each occurrence —H, -halogen, —(C 1 -C 3 ) (alkyl optionally substituted with 1 to 3 halogens), or —OR3, provided that when Y is nitrogen, then R4 or R5 are not attached to Y; R6 is independently at each occurrence —H, -halogen, —CF 3 , —(C 1 -C 3 ) alkyl (optionally substituted with 1 to 3 halogens), or —OR3; and R7 is independently at each occurrence —H, —(C 1 -C 7 ) alkyl, or —(C 2 -C 7 ) alkenyl (optionally substituted with 1 to 3 halogens).