Patent ID: 7951753

Claim:
A library of isolated nucleic acids encoding at least ten different polypeptides, wherein (i) the amino acid sequence of each of the at least ten different polypeptides includes amino acids that differ from those of SEQ ID NOs:127-129 at one or more of positions 13, 14, 33, 35-36, 38, 46-47, 66, 68-69, 71, 79-80, 99, 101-102, 104, and 112-113, and the amino acid differences vary across a plurality of the polypeptides; and (ii) the amino acid sequence of each of the at least ten different polypeptides outside of the residues corresponding to positions 13, 14, 33, 35-36, 38, 46-47, 66, 68-69, 71, 79-80, 99, 101-102, 104, and 112-113, is at least 95% identical to the sequence of SEQ ID NOs: 127-129.