Patent ID: 8252822

Claim:
A compound of formula IIIa: wherein R 1 is optionally substituted C1-C4 alkyl; each R 3 is independently H, halo, C1-C4 alkoxy, or C1-C4 alkyl; R 2 is H, halo, C1-C4 alkoxy, or C1-C4 alkyl; wherein Z is selected from the group consisting of: wherein each R is selected from H, halo, OR′, SR′, CO 2 R′, C(O)NR′ 2 , C═O, CN, OCF 3 , NO 2 , NR′R′, OCOR′, NR′SO 2 R′, SO 2 NR′R′, SO 3 R′, P(O 3 R′), CH(COOR′) 2 , CH(PO 3 R′) 2 , where R′ is independently H, C1-C8 alkyl, C2-C8 heteroalkyl, C1-C8 acyl, C2-C8 heteroacyl, C2-C8 alkenyl, C2-C8 heteroalkenyl, C2-C8 alkynyl, C2-C8 heteroalkynyl, C6-C10 aryl, or C5-C10 heteroaryl, or R is C 1-8 alkyl, C 3-8 cyclic alkyl, C 2-8 alkenyl, C 2-8 alkynyl, an aryl, heteroaryl, a carbocyclic ring or a heterocyclic ring, each of which may contain a heteroatom; or a pharmaceutically acceptable salt thereof.