Patent ID: 8084200

Claim:
A method of diagnosing in a mammal the presence of a tumor in which a nucleic acid encoding a protein is significantly upregulated, wherein the protein comprises an amino acid sequence having at least 95% amino acid sequence identity to: (a) the polypeptide of SEQ ID NO:30; (b) the polypeptide of SEQ ID NO:30, lacking its associated signal peptide; or (c) a polypeptide encoded by the nucleotide sequence of SEQ ID NO:9, the method comprising (i) determining the level of expression of the nucleic acid in a test sample of tissue cells obtained from the mammal and (ii) comparing the level of expression of (i) with the level of expression of the nucleic acid in a control sample, wherein a significantly higher level of expression of the nucleic acid encoding the protein in the test sample, as compared to the control sample, is indicative of the presence of a tumor in which the nucleic acid is significantly upregulated, wherein the tumor is a kidney tumor and the tissue cells are kidney tissue cells.