Patent ID: 6965048

Claim:
A compound of formula (I) wherein R 1 is hydrogen or lower-alkyl; R 2 is selected from hydroxy-lower-alkyl, hydroxy-lower-alkyl substituted with lower-alkyl, hydroxy-cycloalkyl, hydroxy-cycloalkyl substituted with lower-alkyl, carbamoyl-lower-alkyl and carbamoyl-lower alkyl substituted with lower-alkyl; or R 1 and R 2 are bonded to each other to form a ring together with the nitrogen atom to which they are attached and —R 1 —R 2 — is lower-alkylene which is substituted with a group selected from hydroxy, hydroxy-lower-alky and carbamoyl; R 3 is hydrogen or lower-alkyl; R 4 is aryl; W is selected from CO, COO, CONR 5 , CSO, CSNR 5 , SO 2 , and SO 2 NR 5 ; R 5 is hydrogen or lower-alkyl; X is selected from a single bond, O, —CH═CH—, and —C≡C—; m is 0, 1, 2, 3 or 4, wherein m is not 0 if X is O; and n is 0, 1, 2 or 3, wherein m+n is not more than 5.