Patent ID: 8492382

Claim:
A method for the treatment of neuropathic pain in a subject, comprising administering to the subject wherein the subject is human, in need thereof an effective amount of an AT 2 receptor antagonist, wherein the AT 2 receptor antagonist is selected from compounds represented by the formula (II): wherein: R 1 and R 2 are independently selected from H, phenyl, substituted phenyl, benzyl, substituted benzyl, C 1-6 alkyl, substituted C 1-6 alkyl, C 3-6 cyloalkyl, substituted C 3-6 cycloalkyl, heteroaryl, and substituted heteroaryl, substituted biphenylmethylene and saturated and unsaturated substituted biphenylmethylene, provided that one of R 1 or R 2 is not hydrogen, R 4 is selected from a carboxylate, carboxylic acid, sulfate, phosphate, sulfonamide, phosphonamide or amide, X is selected from CH, nitrogen, sulfur or oxygen with the proviso that when X is sulfur or oxygen one of R 1 or R 2 is absent, and Y is selected from sulfur, oxygen or N—R N , where R N is selected from H, C 1-6 alkyl, substituted C 1-6 alkyl, aryl, substituted aryl, benzyl, substituted benzyl, C 1-4 alkylaryl, substituted C 1-4 alkylaryl, OH, or NH 2 , or a pharmaceutically compatible salt thereof.