Patent ID: 8093265

Claim:
A bicycloheteroaryl compound having a formula Ia or Ib: wherein W is CR 4 ; Z is CR 4 ; L 1 is a single bond, or C 1 -C 2 alkylene, unsubstituted or substituted with alkyl, oxo, or hydroxyalkyl; R 1 is selected from substituted or unsubstituted aryl; R 2′ is H or Me; R 3 is selected from hydroxy, amino, alkylamino, and substituted or unsubstituted heterocycloalkyl; provided that when R 3 is hydroxy, amino or alkylamino then L 1 is other than a bond; each R 4 is independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, cyano, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloheteroalkyl, halo, and hydroxy; R 5 is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, cyano, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloheteroalkyl, halo, and hydroxy; or a pharmaceutically acceptable salt thereof; or a stereoisomer, isotopic variant or a tautomer thereof.