Patent ID: 7951823

Claim:
A compound of Formula (1): or pharmaceutically acceptable salts, or stereoisomers thereof, wherein: J is a 5-12 membered monocyclic or fused carbocyclic ring, heteroaryl or heterocyclic ring containing N, O and/or S; R 1 is —(CR 2 ) l —NR 2 , —(CR 2 ) l —NRC(═NR)—NR 2 , —(CR 2 ) l —C(═NR)—NR 2 or a 5-7 membered nitrogen-containing non-aromatic heterocyclic ring; W—R 2 is a substituent at any position on ring A; W is —O(CR 2 ) k —, —S(CR 2 ) k —, —S(O)(CR 2 ) k —, —SO 2 (CR 2 ) k — or —OC(O)(CR 2 ) k —; R 2 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, R 8 , —CR 10 ═CR 10 —R 8 , or wherein ring E is an optionally substituted 5-7 membered monocyclic or fused carbocyclic or heterocyclic ring; or W—R 2 together form C 1-6 alkyl, aryl or —OC(O)NR 6 R 7 ; Y is SO 2 R 3 or SO 2 NR 6 R 7 ; R 3 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, —(CR 2 ) l —C 3-7 cycloalkyl or —(CR 2 ) l —R 8 ; R 4 is —CR 10 ═CR 10 —R 8 , —CR[(CR 2 ) l —R 8 ] 2 , C 2-6 alkynyl, —O—(CR 2 ) l —R 9 , NR 6 R 7 , or an optionally substituted 5-7 membered carbocyclic ring, heterocyclic ring, aryl or heteroaryl; or R 4 together with Y form an optionally substituted 5-12 membered non-aromatic heterocyclic ring; R 5 is halo, C 1-6 alkyl, C 1-6 alkoxy, OR 9 or R 9 ; R 6 and R 7 are independently H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl or —(CR 2 ) l —R 8 ; or R 6 and R 7 together with N may form an optionally substituted 5-7 membered monocyclic or fused heterocyclic ring; X, R 8 and R 9 are independently an optionally substituted 5-7 membered carbocyclic ring, heterocyclic ring, aryl or heteroaryl; or R 9 may be H or C 1-6 alkyl; R 10 is H or C 1-6 alkyl; each R is H, C 1-6 alkyl, C 2-6 alkenyl, or C 2-6 alkynyl, wherein a carbon may optionally be substituted or replaced with NR, O or S; i is 0-1; k, l and m are independently 0-6; n is 1-6; and p is 0-3.