Patent ID: 7964560

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein n is 1, 2, or 3; R 1 is selected from hydroxy and —NHSO 2 R 7 ; R 2 is selected from hydrogen, alkenyl, alkyl, and cycloalkyl; wherein the alkenyl, the alkyl, and the cycloalkyl are optionally substituted with one, two, three, or four halo groups; R 3 is selected from alkenyl, alkyl, aryl, arylalkyl, cycloalkyl, (cycloalkyl)alkyl, heterocyclyl, and heterocyclylalkyl; R 4 is selected from —S—R 8 , —S(O)—R 8 , and —S(O) 2 —R 8 ; R 5 is selected from hydrogen, alkenyl, alkoxyalkyl, alkoxycarbonylalkyl, alkyl, arylalkyl, carboxyalkyl, cyanoalkyl, cycloalkyl, (cycloalkyl)alkyl, haloalkoxyalkyl, haloalkyl, hydroxyalkyl, (NR a R b )alkyl, and NR a R b )carbonylalkyl; R 6 is selected from hydrogen, alkoxycarbonyl, alkyl, alkylcarbonyl, alkylsulfonyl, cycloalkyloxycarbonyl, cycloalkyl, haloalkoxycarbonyl, haloalkyl, haloalkylcarbonyl, (R a R b )carbonyl, and (NR a R b )sulfonyl; or R 6 is selected from phenyl and a five- or six-membered partially or fully unsaturated ring optionally containing one, two, three, or four heteroatoms selected from nitrogen, oxygen, and sulfur; wherein each of the rings is optionally substituted with one, two, three, or four substituents independently selected from alkoxy, alkoxycarbonyl, alkyl, alkylcarbonyl, alkylsulfanyl, carboxy, cyano, cycloalkyl, cycloalkyloxy, halo, haloalkyl, haloalkoxy, NR g R h , (NR j R k )carbonyl, (NR j R k )sulfonyl, and oxo; R 7 is selected from alkyl, aryl, cycloalkyl, (cycloalkyl)alkyl, heterocyclyl, and —NR c R d ; wherein the cycloalkyl is optionally substituted with one group selected from alkyl, halo, and haloalkyl; R 8 is selected from alkoxyalkyl, alkyl, arylalkyl, cycloalkyl, (cycloalkyl)alkyl, haloalkoxyalkyl, and haloalkyl; R a and R b are independently selected from hydrogen, alkoxy, alkoxyalkyl, alkyl, aryl, arylalkyl, cycloalkyl, haloalkoxyalkyl, haloalkyl, heterocyclyl, and heterocyclylalkyl; R c and R d are independently selected from alkoxy, alkyl, aryl, arylalkyl, cycloalkyl, (cycloalkyl)alkyl, heterocyclyl, and heterocyclylalkyl; or R c and R d together with the nitrogen atom to which they are attached form a five or six-membered monocyclic heterocyclic ring; R g and R h are independently selected from hydrogen, alkoxyalkyl, alkoxycarbonyl, alkyl, alkylcarbonyl, arylalkyl, and haloalkyl; and R j and R k are independently selected from hydrogen, alkyl, aryl, arylalkyl, and heterocyclyl; wherein the aryl, the aryl part of the arylalkyl, and the heterocyclyl are optionally substituted with one or two substituents independently selected from alkoxy, alkyl, and halo.