Patent ID: 6908923

Claim:
A compound represented by Formula I: wherein: R 1 is phenyl, pyridinyl, or phenyl substituted with alkyl, halogen, hydroxy, alkoxy, alkylenedioxy, fluoroalkyl, carboxy, carboalkoxy, carboxyalkyl, carboxamido, sulfonamidoalkyl, sulfonamidyoaryl, aminocarbonyl, beuzyloxycarbonylamino, cyano, carbonyl, nitro, dialkylamino, alkylamino, amino, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylsulfonamido, arylthio, arylsulfinyl, arylsulfonyl, amidino, phenyl, benzyl, heteroaryl, heterocyclyl, phenoxy, benzyloxy, or heteroaryloxy; R 2 is fluoro, ethoxycarbonyl, oxazolyl, pyrazinyl, pyridinyl, pyrimidinyl, tetrazolyl or thiazolyl, wherein said oxazolyl, pyrazinyl, pyridinyl, pyrimidinyl, tetrazolyl or thiazolyl is optionally substituted with lower alkoxy or oxo; and R 3 is aryl or heteroaryl each of which is optionally substituted with alkyl, halogen, hydroxy, alkoxy, alkylenedioxy, fluoroalkyl, carboxy, carboalkoxy, carboxyalkyl, carboxamido, sulfonamidoalkyl, sulfonamidyoaryl, aminocarbonyl, benzyloxycarbonylamino, cyano, carbonyl, nitro, dialkylamino, alkylamino, amino, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylsulfonamido, arylthio, arylsulfinyl, arylsulfonyl, amidino, phenyl, benzyl, heteroaryl, heterocyclyl, phenoxy, benzyloxy, or heteroaryloxy; wherein said heteroaryl group is a 5-, 6- or 7-membered heteroaromatic ring containing 1-4 heteroatoms selected from O, N or S; a bicyclic 9- or 10-membered heteroaromatic ring system containing 1-4 heteroatoms selected from O, N or S; or a tricyclic 12- to 14-membered heteroaromatic ring system containing 1-4 heteroatoms selected from O, N or S, or a single stereoisomer, or mixture of stereoisomers, or a pharmaceutically acceptable salt thereof.