Patent ID: 8178687

Claim:
A compound according to formula (I) in which: Het represents a monocyclic or bicyclic, aromatic or partially unsaturated heterocycle—of dihydro or tetrahydro type—, with from 5 to 11 ring members, containing from 1 to 4 heteroatoms chosen from N, O or S, optionally substituted with one or more radicals R1 or R′1, which may be identical or different; R is chosen from the group consisting of X-(A-B) n —CONH 2 , X-(A-B) n —O—CONH 2 , X-(A-B) n —NH—CONH 2 , X—(CH 2 ) m -heterocycloalkyl, X—(CH 2 ) m -aryl and X—(CH 2 ) m -heteroaryl where X represents —O—C(O), —NH—C(O), NH—CS, —NH—CO—CH 2 —O—; —NH—CO—CH 2 —S—CH 2 —CO—NH—; —NH—CO—(CH 2 ) 2 —SO 2 —; —NH—CO—CH 2 —N(CH 3 )—CO—; A and B, which may be identical or different, independently represent a single bond, CH 2 , CH-alkyl or CH-aralkyl, n=1 or 2 and m=0 or 1; and R1 and R′1, which may be identical or different, are selected from the group consisting of H, halogen, CF 3 , nitro, cyano, alkyl, hydroxyl, mercapto, amino, alkylamino, dialkylamino, alkoxy, alkylthio, carboxyl in free form or esterified with an alkyl radical, carboxamide, CO—NH(alkyl), CON(alkyl) 2 , NH—CO-alkyl, sulphonamide, NH—SO 2 -alkyl, S(O) 2 —NHalkyl and S(O 2 )—N(alkyl) 2 , all the alkyl, alkoxy and alkylthio radicals being themselves optionally substituted with one or more radicals, which may be identical or different, chosen from halogen, hydroxyl, alkoxy, amino, alkylamino and dialkylamino; or a pharmaceutically acceptable salt thereof.