Patent ID: 8318938

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein R A represents from 1 to 4 substituents each independently selected from the group consisting of hydrogen, halo, optionally substituted alkyl, amino, acylamino, optionally substituted alkylsulfonyl, aminosulfonyl, nitro, and —OR 13 , where R 13 is hydrogen, alkyl, acyl, alkanoyl, aryloyl, or a phenol protecting group, each of which is optionally substituted; or R A represents from 2 to 4 substituents, where 2 of said substituents are adjacent and are taken together to form an optionally substituted carbocyclic ring or a fused alkylenedioxy group, and each other substituent is independently selected from the group consisting of hydrogen, halo, optionally substituted alkyl, amino, acylamino, optionally substituted alkylsulfonyl, aminosulfonyl, nitro, and —OR 13 , where R 13 is hydrogen, alkyl, acyl, alkanoyl, aryloyl, or a phenol protecting group, each of which is optionally substituted; R D represents 1-4 substituents each independently selected from the group consisting of hydrogen, halo, optionally substituted alkyl, and optionally substituted alkoxy; or R D represents 2-4 substituents where 2 of said substituents are adjacent substituents and are taken together with the attached carbons to form an optionally substituted carbocycle or a fused alkylenedioxy group; R 7 is selected from the group consisting of hydrogen and a group —(CH 2 ) m′ Z′, where m′ is an integer from 0-6 and Z′ is selected from the group consisting of hydrogen, halogen, hydroxy, formyl, C 1 -C 6 alkanoyloxy, optionally substituted benzoyloxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkoxy, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy, C 3 -C 8 halocycloalkyl, C 3 -C 8 halocycloalkoxy, amino, C 1 -C 6 alkylamino, (C 1 -C 6 alkyl)(C 1 -C 6 alkyl)amino, alkylcarbonylamino, N—(C 1 -C 6 alkyl)alkylcarbonylamino, aminoalkyl, C 1 -C 6 alkylaminoalkyl, (C 1 -C 6 alkyl)(C 1 -C 6 alkyl)aminoalkyl, alkylcarbonylaminoalkyl, N—(C 1 -C 6 alkyl)alkylcarbonylaminoalkyl, cyano, nitro, C 1 -C 6 alkylsulfonyl, optionally substituted phenyl, and optionally substituted phenoxy; R 8a is hydrogen; and R 8b is hydrogen; or R 8a and R 8b are taken together to form a double-bonded oxygen; and (a) represents a single bond or a double bond; providing that when (a) is a double bond, the group R 8a is absent.