Patent ID: 7494668

Claim:
Fast water-dispersible tablets containing domperidone for oral administration in an amount with therapeutic efficacy, comprising domperidone or pharmaceutically acceptable salts thereof, characterised in that they contain about 60-80% (w/w) of an auxiliary granulate and about 10-30% (w/w) of a disintegrating agent, expressed in relation to the total weight of the tablets, a sweetener, a flavouring agent and a lubricant, the formulations of which have an enhanced structural integrity, having a friability lower than 1.0%, and are able to disperse in water within 3 minutes, to provide a dispersion that passes through a 710 μm diameter mesh size sieve, that presents a pleasant taste and the absence of perceptible granules in the mouth, characterized in that the auxiliary granulate is D-mannitol granules comprising 3% of maize starch and 97% of D-mannitol, and present less than 3.0% moisture, determined by the Karl-Fishcer method.