Patent ID: 7524836

Claim:
A steroidal compound or a salt thereof having the following general formula: A-B-T C -Y—NO 2 (I) wherein: A=R—, wherein R is a steroidal drug radical as defined hereunder, B=-T B -X 2 -T BI - wherein T B is (CO), T BI is O; X 2 is a bivalent bridging group such that the following precursors of B, having the formula Z-T B -X 2 -T BI -Z′ in which Z and Z′ are independently H or OH, is selected from the following compounds: T C is (CO); Y has the following meanings: a linear or branched C 1 -C 20 alkylenoxy group or a cycloalkylene having from 5 to 7 carbon atoms, in the cycloalkylenic ring one or more carbon atoms can be substituted by heteroatoms, the ring can have side chains of R′ type, R′ being a linear or branched C 1 -C 20 alkyl; or wherein n 3 is an integer from 0 to 3 and n 3′ is an integer from 1 to 3, wherein R 1f =H, CH 3 and nf′ is an integer from 1 to 6; R has the following formula: wherein in substitution of the hydrogen atom of the CH groups or of the two hydrogen atoms of the CH 2 groups mentioned in the general formula, the following substituents can be present: in position 1-2: there may be a double bond; in position 3: there may be C═O, OH; in position 4-5: there may be a double bond; in position 6: there may be Cl, F, CH 3 ; in position 7: there may be Cl, OH; in position 9: there may be Cl, F; in position 11: there may be OH, C═O, Cl, CH 3 ; in position 16: there may be CH 3 , OH; in position 17: there may be OH, CH 3 ; in position 16-17: there may be the following groups: R′″ and R′, equal or different from each other, are hydrogen or CH 3 ; R″ is C(O)CH 2 O—.