Patent ID: 8106035

Claim:
A compound of Formula Ia or Ib, or a pharmaceutically acceptable salt or prodrug thereof: wherein said prodrug is an ester; R 1 and R 2 are independently selected from the group consisting of OH, OC 1-4 alkyl, and halo; R 3 is C 1-4 alkyl; R 5 is selected from the group consisting of C 1-4 alkyl, OC 1-4 alkyl, SC 1-4 alkyl, SO 2 C 1-4 alkyl, P(O)(OC 1-4 alkyl) 2 and SCN; R 6 is selected from the group consisting of C 1-4 alkyl, unsubstituted Ph and Ph substituted with 1-2 groups independently selected from C 1-4 alkyl, OC 1-44 alkyl, OH, CF 3 , OCF 3 , halo, SH, SC 1-4 alkyl, NH 2 , NHC 1-4 alkyl, N(C 1-4 alkyl)(C 1-4 alkyl) and CN; R 7 is selected from the group consisting of C 1-4 alkyl, OC 1-4 alkyl, SC 1-4 alkyl, SO 2 C 1-4 alkyl, P(O)(OC 1-4 alkyl) 2 and SCN; R 8 are either both H or together form ═CH 2 ; and represents a single or a double bond, with the proviso that represents a single bond when R 5 is C 1-4 alkyl or when R 7 is C 1-4 alkyl.