Patent ID: 7105558

Claim:
A compound of the formula (I) or (II) wherein n is from 1 to 4; R 1 is H or C 1 to C 15 hydrocarbyl wherein up to three C atoms may optionally be replaced by an atom independently selected from the group consisting of N, O, and S, and up to three H atoms may optionally be replaced by halogen atoms; R 2 is selected from the group consisting of H, Me, Et, Pr and OH, each R 2 being independently selected from the group consisting of H, Me, Et, Pr and OH when n is greater than 1; R 3 is selected from the group consisting of H, Me, Et and Pr when n is 1; or, when n is greater than 1, each R 3 is independently selected from the group consisting of H, Me, Et and Pr, or two R 3 groups on neighbouring carbon atoms are linked to form a C 3 to C 6 carbocylic ring, or two R 3 groups are absent from neighbouring carbon atoms which are linked by a double bond; R 4 is C 1 to C 15 hydrocarbyl wherein up to two C atoms may optionally be replaced by an atom independently selected from the group consisting of N, O, and S and up to three H atoms may optionally be replaced by halogen atoms; Z is —CO—(NR 6 )—, wherein R 6 is selected from the group consisting of H, Me, Et, Pr and Bn; Q is V is selected from the group consisting of —CO—NH—SO 2 -Ph, —SO 2 —NH—CO-Ph, —CH 2 OH, and a group of the formula —R 8 U, wherein U is selected from the group consisting of —COOH, tetrazolyl, —CONHOH— and —SO 3 H; and R 8 is selected from the group consisting of a bond; C 1 to C 6 hydrocarbylene, optionally substituted by hydroxy, amino or acetamido; —O—(C 1 to C 3 alkylene)-; —SO 2 NR 9 —CHR 19 —; —CO—NR 9 —CHR 10 —, wherein R 9 and R 10 are in dependently selected from H and methyl; and —NH—(CO) c —CH 2 —, c being 0 or 1; T is selected from the group consisting of C 1 to C 6 hydrocarbyl, —NR 11 R 12 wherein R 11 and R 12 are independently selected from H, Me, Et, Pr, Bn, —OMe, —OH, —CH 2 OH, halogen and trihalomethyl; m is 1 or 2; p is from 0 to 3; and q is from 0 to 2; or a pharmaceutically acceptable salt thereof.