Patent ID: 7018647

Claim:
An external skin patch, comprising a substrate and a drug reservoir layer coated on the substrate, in which the drug reservoir layer comprises (1) an adhesive gel base which comprises a water soluble polymeric material, a crosslinking agent, 20 to 60% by weight of water based upon the total weight of the adhesive gel base and a humectant as essential components, together with (2) medicinal components comprising a local anesthetic and a nonsteroidal antiphlogistic analgesic agent, wherein the crosslinking agent is selected from the group consisting of aluminum compounds, wherein the humectant is selected from the group consisting of polyhydric alcohols, saccharides and superabsorbent resins, wherein the local anesthetic is selected from the group consisting of tetracaine, procaine, dibucaine, benzocaine, xylocaine, and pharmaceutically acceptable salts thereof, and wherein the nonsteroidal antiphlogistic analgesic agent is selected from the group consisting ketoprofen, piroxicam, felbinac, bufexamac, suprofen, flurbiprofen, ibuprofen, and pharmaceutically acceptable salts thereof.