Patent ID: 7064100

Claim:
A method for producing a particulate preparation comprising a compound according to formula (I): wherein: R 1 is —H, —CH 3 , optionally substituted (C 2 –C 24 )-alkyl radical, optionally substituted (C 2 –C 24 )-alkenyl radical, optionally substituted alkyl radical containing a (C 1 –C 24 )-alkyl group, or optionally substituted alkenylaryl radical containing a (C 1 –C 24 )-alkyl group; R 2 and R 3 are independently —CH 2 —CN, —CH 3 , —CH 2 —CH 3 , —CH 2 —CH 2 –CH 3 , —CH(CH 3 )—CH 3 , —CH 2 —OH, —CH 2 —CH 2 —OH, —CH(OH)—CH 3 , —CH 2 —CH 2 –CH 2 —OH, —CH 2 —CH(OH)—CH 3 , —CH(OH)—CH 2 —CH 3 , or —(CH 2 CH 2 —O) n H; R 4 and R 5 are independently —H, —CH 3 , optionally substituted (C 2 –C 24 )-alkyl radical, optionally substituted (C 2 –C 24 )-alkenyl radical, optionally substituted alkyl radical containing a (C 1 –C 24 )-alkyl group, optionally substituted alkenylaryl radical containing a (C 1 –C 24 )-alkyl group, —CH 2 —CN, —CH 2 —CH 3 , —CH 2 —CH 2 –CH 3 , —CH(CH 3 )—CH 3 , —CH 2 —OH, —CH 2 —CH 2 —OH, —CH(OH)—CH 3 , —CH 2 —CH 2 —CH 2 —OH, —CH 2 —CH(OH)—CH 3 , —CH(OH)—CH 2 —CH 3 , or —(CH 2 CH 2 —O) n H; n is an integer of 1, 2, 3, 4, 5 or 6; X (−) is a charge-balancing anion; said particulate produced by the steps: a) preparation of an aqueous solution comprising cationic nitrile of formula (I) and optionally alkali metal cumenesulfonate; b) optional adjustment of the solution to an acidic pH; c) atomization and drying of the solution in a fluidized-bed apparatus; d) optional powdering of the resulting primary granules in the fluidized bed; e) consolidation of the optionally powdered primary granules by subsequent spraying with an aqueous consolidation solution, with simultaneous drying in the same or optionally a downstream second fluidized-bed apparatus; f) discharge of the granules from the fluidized-bed apparatus and optional separation of the granules into acceptable granules and coarse/fine granules; g) optional return of the fine granules and/or the ground coarse granules into the fluidized bed in step c); and h) optional return of the fine granules and/or the ground coarse granules into the powdering step of step d).