Patent ID: 7504431

Claim:
A compound of the formula I, its stereoisomers, solvates, and salts, thereof, wherein: a is R 1 , >C 3 alkyl, substituted alkyl, cycloalkyl or aryl; R 1 is —C(O)NR 2 R 3 or C(O)OR 4 —; R 2 and R 3 are independently (a) hydrogen; (b) alkyl, substituted alkyl, cycloalkyl, aryl, (aryl)alkyl, or (cycloalkyl)alkyl, b is CR 13 R 14 ; c is aryl; R 4 is hydrogen, alkyl, substituted alkyl, cycloalkyl, aryl, (aryl)alkyl or (cycloalkyl)alkyl; -d-(CH 2 ) m -f is selected from l, m, and n are independently 0 to 4; R a , R 13 and R 14 are independently hydrogen, cyano, nitro, halogen, alkyl, substituted alkyl, aryl, cycloalkyl, —OR 15 , —SR 15 , —OC(═O)R 15 , —C(═O)R 15 , —CO 2 R 15 , —C(═O)NR 16 R 17 , —NR 16 R 17 , —S(═O)R 15 ; or —SO 2 R 15 ; or R 13 and R 14 are taken together to form oxo; R 15 , R 16 and R 17 are independently hydrogen, alkyl, substituted alkyl, cycloalkyl, aryl, (aryl)alkyl, or (cycloalkyl)alkyl,; and R 21 and R 22 are independently hydrogen or C 1-4 alkyl; provided that: when c is phenyl and R a is located para to the sulfoxide substituent; R a is not chloro or —OMe; and when a is >C 3 alkyl, n is 0.