Patent ID: 7687257

Claim:
A device for separating and/or detecting a plurality of molecular targets in solution in a complex mixture, said device comprising: a. a capillary network having at least one capillary allowing movement of the complex mixture introduced into the device, said capillary network extending substantially in one plane, wherein said at least one capillary is without floor and top; b. two sets of electrodes disposed respectively in two face to face different planes which are substantially parallel to the plane of the capillary network, the capillary network being disposed between the two sets of electrodes so that one of the sets of electrodes forms the floor of said at least one capillary and that the other of the sets of electrodes forms the top of said at least one capillary, said two sets of electrodes comprising: a set of functionalized electrodes, the functionalized electrodes being grafted to probes which are organized into spots and which are located into said at least one capillary, each probe being capable of retaining a specific molecular target present in the complex mixture, by specific probe/target binding; and a set of non-functionalized electrodes; wherein the set of functionalized or non-functionalized electrodes comprises first parallel row electrodes and second parallel row electrodes, which are superimposed and perpendicular to the first parallel row electrodes so as to form a grid of electrodes in one plane, and wherein each mesh of the grid defines a space in which a small electrode and one or two field effect transistors are disposed, each field effect transistor having a transistor gate connected to one of the first parallel row electrodes of one side of the mesh, an inlet terminal connected to one of the second parallel row electrodes of another side of the mesh, and an outlet terminal connected to the small electrode.