Patent ID: 7799800

Claim:
A compound of the following Formula I: wherein: R 1 has the formula alkylene-L-R 1-1 , alkenylene-L-R 1-1 , or alkynylene-L-R 1-1 , wherein: the alkylene, alkenylene, and alkynylene groups are optionally interrupted with one or more —O— groups; L is a bond or a functional linking group selected from the group consisting of —NH—S(O) 2 —, —NH—C(O)—, —NH—C(S)—, —NH—S(O) 2 —NR 3 —, —NH—C(O)—NR 3 —, —NH—C(S)—NR 3 —, —NH—C(O)—O—, —O—, —S—, and —S(O) 2 —; and R 1-1 is a linear or branched aliphatic group having at least 11 carbon atoms, optionally including one or more unsaturated carbon-carbon bonds; R″ is selected from the group consisting of: hydrogen; alkyl; alkenyl; aryl; heteroaryl; heterocyclyl; alkylene-Y-alkyl; alkylene-Y-alkenyl; alkylene-Y-aryl; and alkyl or alkenyl substituted by one or more substituents selected from the group consisting of: —OH; halogen; —N(R 4 ) 2 ; —C(O)—C 1-10 alkyl; —C(O)—O—C 1-10 alkyl; —N 3 ; aryl; heteroaryl; heterocyclyl; —C(O)-aryl; and —C(O)-heteroaryl; wherein aryl is phenyl, naphthyl, biphenyl, fluorenyl or indenyl; heteroaryl is furyl, thienyl, pyridyl, quinolinyl, isoquinolinyl, indolyl, isoindolyl, triazolyl, pyrrolyl, tetrazolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, benzofuranyl, benzothiophenyl, carbazolyl, benzoxazolyl, pyrimidinyl, benzimidazolyl, quinoxalinyl, benzothiazolyl, naphthyridinyl, isoxazolyl, isothiazolyl, purinyl, quinazolinyl, pyrazinyl, or 1-oxidopyridyl; and heterocyclyl is the fully saturated or partially unsaturated derivative of any one of the above heteroaryl groups, pyrrolidinyl, tetrahydrofuranyl, morpholinyl, thiomorpholinyl, piperidinyl, piperazinyl, thiazolidinyl, imidazolidinyl, isothiazolidinyl, tetrahydropyranyl, quinuclidinyl, or homopiperidinyl; wherein: Y is —O— or —S(O) 0-2 —; and each R 4 is independently selected from the group consisting of hydrogen, C 1-10 alkyl, and C 2-10 alkenyl; R A and R B are taken together to form a fused benzene ring or a fused 5- to 7-membered saturated ring not containing a heteroatom, and unsubstituted or substituted by one or more R groups; each R is independently selected from the group consisting of halogen, hydroxy, alkyl, alkenyl, haloalkyl, alkoxy, alkylthio, and —N(R 3 ) 2 ; and each R 3 is independently selected from the group consisting of hydrogen and alkyl; with the proviso that when L is —NH—S(O) 2 — and R A and R B join to form an unsubstituted benzene ring, R 1-1 is a linear or branched aliphatic group having greater than 16 carbon atoms, optionally including one or more unsaturated carbon-carbon bonds; or a pharmaceutically acceptable salt thereof.