Patent ID: 7507737

Claim:
A chemical entity that is a compound of Formula (I): wherein each of R 1-4 is independently H, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, phenyl, —CF 3 , —OCF 3 , —ON, halo, —NO 2 , —OC 1-4 alkyl, —SC 1-4 alkyl, —S(O)C 1-4 alkyl, —SO 2 C 1-4 alkyl, —C(O)C 14 alkyl, —C(O)phenyl, —C(O)NR a R b , —CO 2 C 1-4 alkyl, —CO 2 H, —C(O)NR a R b , or —NR a R b ; wherein R a and R b are each independently H, C 1-4 alkyl, or C 3-7 cycloalkyl; one of X 1 and X 2 is N and the other is C-R c ; where R c is H, methyl, hydroxymethyl, dimethylaminomethyl, ethyl, propyl, isopropyl, —CF 3 , cyclopropyl, or cyclobutyl; n is 1 or 2; Z is N, CH, or C(C 1-4 alkyl); R 6 is H, C 1-6 alkyl, or monocyclic cycloalkyl; R 8 is H or C 1-4 alkyl; R 9 and R 10 are each independently H or C 1-4 alkyl; and R 11 is H or C 1-4 alkyl; or a pharmaceutically acceptable salt of compound of Formula (I).