Patent ID: 8394801

Claim:
A quinoxaline compound represented by formula I in which X is: oxygen or sulphur; R 1 is: (i) hydrogen, (ii) unsubstituted or substituted (C 1 -C 12 )-alkyl, (iii) cyano, (iv) halogen, R 2 and R 3 are independently: (i) hydrogen, (ii) unsubstituted or substituted (C 1 -C 12 )-alkyl, R 4 is: (i) hydrogen, (ii) unsubstituted or substituted (C 1 -C 12 )-alkyl, (iii) unsubstituted or substituted cycloalkyl, (iv) unsubstituted or substituted heterocyclyl, (v) unsubstituted or substituted alkylaryl, (vi) unsubstituted or substituted alkylheteroaryl, and R 5 and R 8 are independently: (i) hydrogen, (ii) unsubstituted or substituted (C 1 -C 12 )-alkyl, (iii) unsubstituted or substituted aryl, (iv) unsubstituted or substituted heteroaryl, (v) halogen, (vi) cyano, (vii) hydroxy, (viii) (C 1 -C 12 )-alkoxy, (ix) amino, (x) carboxy, alkoxycarbonyl, carboxyalkyl or alkoxycarbonylalkyl, (xi) alkoxycarbonylamino, alkoxycarbonylaminoalkyl, and R 6 , R 7 are independently: (i) hydrogen, (ii) unsubstituted or substituted aryl, (iii) unsubstituted or substituted heteroaryl, (iv) halogen, (v) cyano, (vi) hydroxy, (vii) (C 1 -C 12 )-alkoxy, (viii) amino, (ix) carboxy, alkoxycarbonyl, carboxyalkyl or alkoxycarbonylalkyl, (x) alkoxycarbonylamino, alkoxycarbonylaminoalkyl, and with the proviso that at least one of R 5 , R 6 , R 7 and R 8 are independently an unsubstituted or substituted aryl or heteroaryl radical, and where the substituents are selected from the group consisting of F, Cl, Br, I, CN, CF 3 , NH 2 , NH-alkyl, NH-aryl, N(alkyl) 2 , NH—CO-alkyl, NH—CO-aryl, NH—CO-heteroaryl, NH—SO 2 -alkyl, NH—SO 2 -aryl, NH—SO 2 -heteroaryl, NH—CO—NH-alkyl, NH—CO—NH-aryl, NH—CO—NH-heteroaryl, NH—C(O)O-alkyl, NH—C(O)O-aryl, NH—C(O)O-heteroaryl, NO 2 , SH, S-alkyl, OH, OCF 3 , O-alkyl, O-aryl, O—CO-alkyl, O—CO-aryl, O—CO-heteroaryl, O—C(O)O-alkyl, O—C(O)O-aryl, O—C(O)O-heteroaryl, O—CO—NH-alkyl, O—CO—N(alkyl) 2 , O—CO—NH-aryl, O—CO—NH-heteroaryl, OSO 3 H, OSO 2 -alkyl, OSO 2 -aryl, OSO 2 -heteroaryl, OP(O)(OH) 2 , alkyl-P(O)(OH) 2 CHO, CO 2 H, C(O)O-alkyl, C(O)O-aryl, C(O)O-heteroaryl, CO-alkyl, CO-aryl, CO-heteroaryl, SO 3 H, SO 2 —NH 2 , SO 2 —NH-alkyl, SO 2 —NH-aryl, SO 2 —NH-heteroaryl, alkyl, cycloalkyl, heterocyclyl, aryl and heteroaryl, where the radicals “alkyl”, “cycloalkyl”, “heterocyclyl”, “aryl” and “heteroaryl” may also be substituted, or a physiologically acceptable salt, stereoisomer or tautomer thereof.