Patent ID: 8518958

Claim:
A compound having a structure represented by formula (I) or any tautomeric or stereoisomeric form thereof, wherein R 1 is selected from hydrogen, —C 1-6 alkyl, —C 2-6 -alkenyl, —C 2-6 -alkynyl, —C 3-6 -cycloalkyl and —C 3-6 -cycloalkenyl; V is selected from a bond, —O—, —N(R 11 )—, —C(═X)—, —S(O) n —, —C(═X)—O—, —C(═X)—N(R 11 )—, —C(═X)—S—, —C(═X)—N(R 11 )—N(R 11 )—, —N(R 11 )—C(═X)—, —N(R 11 )—C(═X)—N(R 11 )—, and —N(R 11 )—S(O) n —, with n=1 or 2; R 2 is selected from hydrogen, -alkyl, -alkenyl, -alkynyl, -cycloalkyl, -cycloalkenyl, -heterocycloalkyl, -heterocycloalkenyl, -aryl and -heteroaryl; or, R 1 and R 2 , together with V and the nitrogen atom they are attached to, form a heterocycle; R 3 is selected from hydrogen, —C 1-6 alkyl, —C 2-6 -alkenyl, —C 2-6 -alkynyl, —C 3-6 -cycloalkyl, —C 3-6 -cycloalkenyl and halogen; W is a bond, or —C(═O); R 4 is selected from hydrogen, phenyl, and substituted phenyl; R 5 is selected from -alkyl, -alkenyl, -alkynyl, -cycloalkyl, -cycloalkenyl, —(C-linked-heterocycloalkyl), —(C-linked-heterocycloalkenyl), -aryl, and -heteroaryl; X is independently selected from ═O, ═S, ═NR 12 , ═N—OR 13 , ═N—N(R 11 ) 2 , ═N—N(R 11 )(R 12 ), and ═N—N(R 12 ) 2 ; R 10 is independently selected from —C 1-6 alkyl, —C 2-6 -alkenyl, —C 2-6 -alkynyl, —C 3-6 -cycloalkyl and —C 3-6 -cycloalkenyl; R 11 is independently selected from hydrogen and R 10 ; R 12 is independently selected from -alkyl, -alkenyl, -alkynyl, -cycloalkyl, -cycloalkenyl, -heterocycloalkyl, -heterocycloalkenyl, -aryl and -heteroaryl; R 13 is independently selected from hydrogen and R 12 ; wherein R 2 , R 4 , R 5 , R 10 , and R 12 may optionally be substituted; or any pharmaceutically acceptable salt thereof.