Patent ID: 8617583

Claim:
An implantable drug depot useful for reducing, preventing, or treating a hematoma, edema or a deep vein thrombosis in a patient in need of such treatment, the implantable drug depot comprising a therapeutically effective amount of an alpha adrenergic agonist, the drug depot being implantable locally at a site beneath the skin to reduce, prevent or treat a hematoma, edema or a deep vein thrombosis, wherein the drug depot is capable of releasing an effective amount of the alpha adrenergic agonist over a period of at least seven days to about fifteen days and comprises at least one biodegradable polymer comprising poly(D,L-lactide), poly(D,L-lactide-co-caprolactone) or poly(L-lactide-co-caprolactone) or a combination thereof and the polymer has an average molecular weight of from about 5,000 to about 500,000 and a modulus of elasticity in the range of about 1Ã—10 2 to about 3Ã—10 5 dynes/cm 2 , and the drug depot is in the form of a coating disposed on a medical device and the drug depot comprises methoxypoly(ethylene glycol) (mPEG).