Patent ID: 8802433

Claim:
A method for activating macrophage phagocytosis by macrophages or macrophage-like cells or promoting cytokine production in macrophages or macrophage-like cells, comprising: (a) obtaining a culture by culturing a microorganism belonging to Aureobasidium sp.; and (b) administering to the macrophages or macrophage-like cells a composition comprising said culture and compound (1) wherein the microorganism belonging to Aureobasidium sp. is Aureobasidium pullulans M-1 (FERM BP-08615), wherein the composition comprises Compound 1 at 10 μM, wherein the composition is in an amount effective for activating macrophage phagocytosis synergistically by the macrophages or macrophage-like cells or promoting cytokine production synergistically in macrophages or macrophage-like cells.