Patent ID: 8877265

Claim:
A method of making a supercritical fluid extract of Aloe vera for treating hyperglycemia, wherein the method comprises the following (a) and (b): (a) preparing powdery Aloe vera mesophyll, wherein said mesophyll part excludes leaf skin of Aloe vera , by removing water from the mesophyll part of Aloe vera by freeze-drying or hot-air drying to provide a powdery Aloe vera mesophyll; and (b) extracting the powdery Aloe vera mesophyll by supercritical fluid extraction with an extraction solvent, wherein said extraction solvent is carbon dioxide, at an extraction temperature within a range of 50 to 69° C., at a pressure within a range of 15 to 24 MPa, at an extraction time within a range of 50 to 70 minutes, and without using an entrainer to provide the super critical fluid extract of Aloe vera , wherein the supercritical fluid extract of Aloe vera comprises a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more, and wherein supercritical fluid extract of Aloe vera contains one or more anthroquinone compounds in an amount of 0.001% or less.