Patent ID: 7670579

Claim:
A method for manufacture of high purity, nanosized particles of a partially water soluble compound for in vivo use, said compound comprised of a first component and a second component, said components capable of precipitation in chemical combination as solid particles of said compound, said method comprising the steps of; (a) forming a first solely liquid solution of said first component of said compound and a weak acid liquid solvent of said first component; (b) forming a second solely liquid solution of said second component of said compound and a second liquid solvent of said second compartment, said first and second solutions each including ionic species in solution derived from the first and second compounds respectively; (c) directing said first and second solutions with a gas through a respective first and a second spray nozzle to generally simultaneously and separately atomize each of said first and second solutions into a spray; (d) directing and combining said first and second atomized solutions into a common chamber at a temperature to evaporate the first and second liquid solvents and effect thereby chemical combination of ionic species derived from said first and second components to form said compound as dry nano particles; and (e) collecting said nano particles.