Patent ID: 8257917

Claim:
A method for diagnosing Sjögren's Syndrome in a subject, the method comprising the steps of: (a) analyzing a saliva sample from the subject with an assay that specifically detects the level of a marker selected from Table 1, Table 4, or FIG. 4 ; and (b) determining whether the marker level is increased or decreased from a standard control, wherein the increase for IGHG1 protein hypothetical protein Ig gamma-1 chain C region (protein #23, Table 1), Ig gamma-1 chain C region (protein 35, Table 1) and Ig kappa chain C region (protein 39, Table 1) is 1.79 or more relative to a control as measured by LC QpTOF MS; and thereby providing a diagnosis for Sjögren's Syndrome.