Patent ID: 7901073

Claim:
A silicone hydrogel polymer comprising the reaction product of two or more crosslink agents, a hydrophilic monomer and a silicone-containing lens monomer or macromer, wherein at least one of the two or more crosslink agents is selected from formula I or formula II wherein R 1 , R 2 , R 3 , R 4 , R 7 and R 8 are independently selected from hydrogen, C 1 -C 4 alkyl, C 1 -C 2 alkanol or hydroxyl; A is O, O(CH 2 CH 2 O) v or [SiR 5 R 6 O] w SiR 5 R 6 , wherein R 5 and R 6 are independently selected from C 1-4 -alkyl or phenyl, and v is from 1-20 and w is from 0 to 60; m and n are integers independently selected from 1 to 10; p is 0 or 1; and q is an integer from 0 to 6; and X and Y are independently selected from O or NR 9 , wherein R 9 is hydrogen, C 1 -C 4 alkyl or C 1 -C 2 alkanol; or at least one of the two or more crosslink agents is selected from formula III wherein R 1 , R 2 , A and p are defined above, and m is 1, 2 or 3; and n and n′ are integers independently selected from the integers 1 to 10; wherein the hydrophilic monomer has a reactivity ratio R h =k hh /k nx and the crosslink agent of formula I, formula II or formula III has a reactivity ratio R x =k xx /k xh , wherein k hh , k hx , k xx and k xh are the propagation constants for the following radical polymerization reactions, and M h represents the hydrophilic monomer, M h * represents the hydrophilic monomer radical, M x represents the crosslink agent of formula I, II or III, and M x * represents the crosslink agent radical of general formula I, II, or III M h *+M h →M h M h *k hh ; M h *+M x →M h M x *k hx ; M x *+M x →M x M x *k xx ; M x *+M h →M x M h *k xh ; and the ratio R h /R x is from 0.1 to 10, the silicone containing lens monomer has a reactivity ratio R l =k ll /k ly and a second crosslink agent has a reactivity ratio R y =k yy /k yl , wherein k ll , k ly , k yy and k yl are the propagation constants for the following radical polymerization reactions, and M l represents the silicone-containing lens monomer, M l * represents the silicone-containing lens monomer radical, M y represents the second crosslink agent, and M y * represents the second crosslink agent radical, M l *+M l →M l M l *k ll ; M l *+M y →M l M y *k ly ; M y *+M y →M y M y *k yy ; M y *+M l →M y M l *k yl ; and the ratio R l /R y is from 0.1 to 10, and the hydrophilic monomer and the silicone containing lens monomer have a ratio, R H /R L , greater than 10 or less than 0.1, wherein the propensity of the crosslink agents of formula I, II and III to polymerize with the hydrophilic monomer and the propensity of the second crosslink agent to polymerize with the silicone lens monomer provides a silicone hydrogel polymer for use as an ophthalmic lens.