Patent ID: 8349555

Claim:
A method for predicting a clinical outcome for a human subject having prostate cancer, comprising: determining the mRNA expression of a set of genes in a sample from the human subject having prostate cancer, wherein the set of genes consists of the following 11 genes GBX2, MK167, CCNB1, BUB1, KNTC2, USP22, HCFC1, RNF2, ANK3, FGFR2, and CES1, and determining the stem cell-resembling phenotype association index (“SPAI”) for the set of genes in the sample by comparison of the mRNA expression of each of the 11 genes from the human subject having prostate cancer to each of the 11 genes in a reference sample from a stem cell, wherein said stem cell is a peripheral nervous system neurosphere; wherein a subject whose sample has a positive SPAI is predicted to have a poor clinical outcome and a subject whose sample has a negative SPAI is predicted to have a good clinical outcome.