Patent ID: 8734831

Claim:
A method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid coating layer containing a bioactive factor, comprising: (a) forming a porous ceramic scaffold comprised of a ceramic material having pores by freeze-drying using camphene as a freezing medium, the ceramic material being selected from the group consisting of hydroxyapatite (HA), tricalcium phosphate (TCP), biphasic calcium phosphate (BCP), alumina, and zirconia; (b) mixing a silica xerogel and a physiologically active organic substance in a volumetric ratio ranging from 30:70 to 90:10 and treating by a sol gel method to prepare an organic/inorganic hybrid composite solution; (c) adding a bioactive factor to the organic/inorganic hybrid composite solution and agitating until gelation occurs; and (d) coating the porous ceramic scaffold with the organic/inorganic composite containing the bioactive factor added thereto.