Patent ID: 8198254

Claim:
A method of treating a breast cancer patient comprising the steps of: obtaining a breast cancer biopsy sample from the patient; detecting elevated expression of an ANXA9 gene in a tumor cell in the sample of said patient, whereby detection of elevated ANXA9 gene expression predicting poor prognosis for survival, and wherein said ANXA gene comprising the sequence of SEQ ID NO:1 and elevated ANXA9 gene expression is detected by detecting an isolated polynucleotide comprising the sequence of SEQ ID NO:1; and administering to the patient an effective amount of a therapeutic composition comprising an inhibitor of ANXA9 gene expression or ANXA9 protein function, wherein the therapeutic composition being administered inhibits expression of SEQ ID NO:1 or an expression product of SEQ ID NO:1 and wherein the therapeutic composition is an siRNA oligonucleotide inhibitor.