Patent ID: 8853412

Claim:
A compound of the formula I in which X is selected from the group consisting of CH 2 and CH 2 -CH 2 ; R 1a is selected from the group consisting of H, F, Cl, Br, (C 1 -C 6 )-alkyl and CN; R 1b is selected from the group consisting of H, F, Cl and (C 1 -C 6 )-alkyl; R 1c is selected from the group consisting of H, F, Cl and (C 1 -C 6 )-alkyl; R 2a is selected from the group consisting of H, F, Cl, Br, (C 1 -C 6 )-alkyl, CN, CO 2 R 5 and CONR 5 R 5′ ; R 2b is selected from the group consisting of H, F, Cl and (C 1 -C 6 )-alkyl; R 2c is selected from the group consisting of H, F, Cl and (C 1 -C 6 )-alkyl; R 5 , R 5′ are independently of each other selected from the group consisting of H and (C 1 -C 4 )-alkyl; one of the groups Y 1 and Y 2 is N, N-oxide or CR 2d , the other is C—Z—R 3 —R 4 ; R 2d is selected from the group consisting of H, F, Cl and (C 1 -C 4 )-alkyl; Z is selected from the group consisting of a bond, O, CO, COO, S, SO and SO 2 ; R 3 is selected from the group consisting of a bond and (CR6R6′) n ; R 6 , R 6′ are independently of each other selected from the group consisting of H and (C 1 -C 6 )-alkyl, which is unsubstituted or monofluorinated and the overall number of carbon atoms in a (CR 6 R 6′ ) n group is below or equal to eight (8); n is selected from the group consisting of 1, 2, 3, 4 and 5; R 4 is selected from the group consisting of (C 1 -C 6 )-alkyl, mono-, di- or trifluorinated (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, CO 2 R 5 , OR 7 , NR 8 R 8′ , SR 9 , (C 3 -C 8 ) -cycloalkyl, a 4- to 6-membered heterocycle, which comprises one or two identical or different ring heteroatoms selected from the group consisting of N and O, phenyl, a 5- to 6-membered heteroaryl, which comprises one, two or three identical or different ring heteroatoms selected from the group consisting of N, O and S, wherein all cyclic groups within R 4 are unsubstituted or substituted by one to three identical or different substituents selected from the group consisting of (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkanoyl, hydroxy-(C 0 -C 4 )-alkyl, (C 1 -C 3 )-alkoxy-(C 0 -C 4 )-alkyl, oxo (═O), F and Cl; R 7 is selected from the group consisting of H, (C 1 -C 6 )-alkyl, hydroxy-(C 1 -C 4 )-alkyl and (C 1 -C 3 )-alkoxy-(C 1 -C 4 )-alkyl; R 8 , R 8′ are independently of each other selected from the group consisting of H and (C 1 -C 6 )-alkyl and R 9 is (C 1 -C 6 )-alkyl; in any of its stereoisomeric forms, or a mixture of stereoisomeric forms in any ratio, or a physiologically acceptable salt thereof, or a physiologically acceptable solvate of any of them.