Patent ID: 8324231

Claim:
A compound in the form of Formula I, or a pharmaceutically acceptable salt thereof, wherein X is O or S; R 1 is phenyl substituted with —O—CH 2 —C(H)(CH 3 ) 2 ; R 2 is benzodioxolyl, benzofuranyl, imidazolyl, 1,2-dihydro-2H-benzimidizol-2-one, 1,3-dihydro-2H-benzimidizol-2-one, thiazolyl, indazolyl, furanyl, or benzisoxazolyl, wherein each of said benzodioxolyl, benzofuranyl, imidazolyl, 1,2-dihydro-2H-benzimidizol-2-one, 1,3-dihydro-2H-benzimidizol-2-one, thiazolyl, indazolyl, furanyl, or benzisoxazolyl is optionally substituted with 1, 2 or 3 groups, which can be the same or different, selected from —N(H)(C 1 -C 6 )alkyl-N(H)C(O)—(C 1 -C 6 )alkyl-N[(C 1 -C 6 )alkyl] 2 , —N(H)(C 1 -C 6 )alkyl-R 9 , —(C 1 -C 6 )alkyl, —N[(C 1 -C 6 )alkyl](C 1 -C 6 )alkyl-R 10 , —N(H)C(O)(C 1 -C 6 )alkyl-N[(C 1 -C 6 )alkyl] 2 , —O—(C 1 -C 6 )alkyl, —NH 2 , —N(H)(C 1 -C 6 )alkyl-N([C 1 -C 6 )alkyl] 2 , —N(H)C(O)—(C 1 -C 6 )alkyl, phenyl optionally substituted with halo, —N(H)(C 1 -C 6 )alkyl-(C 6 -C 10 )aryl optionally substituted with halo or alkoxy at any ring position, and —N(H)(C 1 -C 6 )alkyl-NH 2 ; R 3 is H and each of R 9 , and R 10 are independently selected from H, —OH, halo, —CF 3 , —O(C 1 -C 6 )alkyl, —(C 6 -C 10 )aryl optionally substituted with halo or alkoxy, —O—(C 1 -C 6 )alkyl-(C 6 -C 10 )aryl, —(C 3 -C 10 )cycloalkyl, —CN, -(5-10 membered)heteroaryl, -(4-10 membered)heterocycloalkyl, —NH 2 , —N(H)(C 1 -C 6 )alkyl, and —N(H)[(C 1 -C 6 )alkyl] 2 .