Patent ID: 8232424

Claim:
A method for radiolabeling synthesis of an acid, comprising: (a) providing a UV reactor assembly comprising a reaction chamber with a gas inlet and a liquid inlet, a UV spot light source with a light guide, wherein the light guide is used to provide photo irradiation of a reaction mixture through a window in the reaction chamber, (b) dissolving triethylamine (TEA) and a sulfoxide in a solvent, (c) adding an alkyl or aryl iodide to the solution of step (b) to give a reagent volume to be labeled, (d) introducing a radiolabeled carbon-isotope monoxide enriched gas-mixture into the reaction chamber of the UV reactor assembly via the gas inlet, (e) introducing said reagent volume into the reaction chamber via the liquid inlet, using a pressure that is about 80 times higher than the pressure before the introduction, in order to maintain a pseudo one-phase system, (f) turning on the UV spot light source and waiting for a predetermined time while the radiolabeling synthesis occurs, and (g) collecting the radiolabeled acid from the reaction chamber.