Patent ID: 7151096

Claim:
A compound of Formula I: in which n is chosen from 0, 1, 2 and 3; R 1 is chosen from hydrogen and C 1-10 alkyl; R 2 is pyrimidinyl optionally substituted by one to three radicals chosen from halo, C 1-10 alkyl, halo-substituted C 1-4 alkyl, C 1-10 alkoxy and halo-substituted C 1-4 alkoxy; wherein N(R 1 ) is bonded at the 2 position of pyrimidinyl; R 3 is pyridinyl optionally substituted by one to three radicals chosen from halo, C 1-10 alkyl, halo-substituted C 1-4 alkyl, C 1-10 alkoxy and halo-substituted C 1-4 alkoxy; R 4 is chosen from —XNR 6 (CH 2 ) m NR 7 C(O)—, —XNR 6 (CH 2 ) m NR 7 C(O)CH 2 —, XNR 6 (CH 2 ) m NR 7 (CH 2 ) m NR 7 C(O)—, —O(CH 2 ) m NR 7 C(O)—, —XNR 6 (CH 2 ) m O— and —XNR 6 (CH 2 ) m NR 7 CH 2 —; wherein X is a bond or C 1-4 alkylene; m is chosen from 1, 2, 3, 4, 5 and 6; R 6 and R 7 independently are chosen from hydrogen and C 1-10 alkyl; and R 5 is chosen from halo, C 1-10 alkyl, halo-substituted C 1-4 alkyl, C 1-10 alkoxy, halo-substituted C 1-4 alkoxy, morpholino-methyl and piperazinyl; wherein any morphlino or piperazinyl of R 5 is optionally substituted with a group chosen from halo, C 1-6 alkyl, halo-substituted C 1-4 alkyl, C 1-10 alkoxy, halo-substituted C 1-4 alkoxy and —XNR 8 R 9 , wherein X is a bond or C 1-4 alkylene; R 8 and R 9 are independently chosen from hydrogen and C 1-10 alkyl optionally substituted by halo or amino; or a salt thereof.