Patent ID: 7414028

Claim:
A heparin-binding growth factor (HBGF) of formula I: wherein: each X is a peptide chain that binds a heparin-binding growth factor receptor (HBGFR) and is selected from SEQ ID NOs 11, 20, 23, 24, 25, 26, 33, 34, 35, and 36; R 1 is an amino acid, selected from the group consisting of lysine, ornithine, or citrulline wherein X is covalently bonded through the N-terminus of R 1 or through a side chain of R 1 ; R 2 is a trifunctional alpha amino acid, selected from the group consisting of lysine, ornithine, or citrulline wherein X is covalently bonded through a side chain of R 2 ; and R 3 is a chain from 7 to about 50 atoms covalently bonded to R 2 , wherein R 3 is not found in the natural ligand of the heparin-binding growth factor receptor (HBGFR) which X binds.