Patent ID: 8633312

Claim:
A compound of the formula I wherein one of the ring atoms X and Y represents CH 2 and the other represents O, S, SO, SO 2 or NR5; or —X—Y— represents —CH 2 —CH 2 — or —CH═CH—; R1 is chosen from A) RO—, wherein R is chosen from: a) C 1 -C 6 -alkyl, which is substituted by 1, 2 or 3 hydroxyl or C 1 -C 6 -alkoxy groups; b) C 1 -C 6 -alkyl, which is substituted by a saturated or unsaturated, non-aromatic heterocyclic radical having 5 or 6 ring atoms, which contains 1, 2 or 3 hetero atoms which are chosen independently of each other from O, N and S, wherein the heterocyclic radical can optionally contain 1 or 2 hydroxy, C 1 -C 6 -alkoxy or C 1 -C 6 -alkyl substituents and can be condensed with a phenyl ring or a saturated or unsaturated carbocyclic radical having 5 or 6 ring atoms; c) a non-aromatic heterocyclic radical having 5 or 6 ring atoms, which contains 1 or 2 hetero atoms which are chosen independently of each other from O and N; d) C 1 -C 6 -alkyl; e) H; f) C 1 -C 6 -alkyl, which is substituted by NR6R7; g) CF 3 SO 2 —; h) C 1 -C 6 -alkylcarbonyloxy-C 1 -C 6 -alkyl; and i) (C3-C7-cycloalkyl)-C 1 -C 6 -alkyl, which can optionally contain 1 or 2 hydroxy, C 1 -C 6 -alkoxy or C 1 -C 6 -alkyl substituents on the cycloalkyl radical; B) NR6R7; C) tetrazolo; and D) NR8CONR13R14; R2 represents H or C 1 -C 6 -alkyl; R3 is chosen from: and e) —NH—C 1 -C 6 -alkylene-NR6R7 R4 represents H, halogen or C 1 -C 6 -alkyl; R5 represents H or C 1 -C 6 -alkyl, which is substituted by 1, 2 or 3 hydroxyl or C 1 -C 6 -alkoxy groups; R6 and R7, which can be identical or different, represent H or C 1 -C 6 -alkyl, which is substituted by 1, 2 or 3 hydroxyl or C 1 -C 6 -alkoxy groups; R8 represents H or C 1 -C 6 -alkyl; R9, R10 and R11, which can be identical or different, are chosen from: a) H, b NH 2 , c) mono-C 1 -C 6 -alkylamino, d) di-C 1 -C 6 -alkylamino, e) C 1 -C 6 -alkyl, f) C 1 -C 6 -alkoxy, g) hydroxyl, h) halogen, i) C 1 -C 6 -alkyl, which is substituted by 1, 2 or 3 halogen atoms; j) CONR6R7; and k) NO 2 ; R12 represents H or NH 2 ; R13 and R14, which can be identical or different, represent H or C 1 -C 6 -alkyl, or together with the nitrogen atom to which they are bonded form a non-aromatic heterocyclic radical having 5 or 6 ring atoms, which contains 1 or 2 hetero atoms which are chosen independently of each other from O and N; and the optical isomers, physiologically acceptable salts and solvates thereof.