Patent ID: 6969517

Claim:
A method of treating a human patient having a cancer associated with EpCAM over-expression, said method comprising the step of administering an anti-EpCAM protein, wherein the protein comprises an antibody that binds human EpCAM, said antibody comprising a light chain comprising (i) amino acid residues 24-31 of SEQ ID NO: 1; (ii) amino acid residues 49-55 of SEQ ID NO: 1; and (iii) amino acid residues 88-96 of SEQ ID NO: 1; and further comprising an amino acid sequence defining an immunoglobulin light chain framework region selected from the group consisting of: (i) amino acid residues 1-23 of SEQ ID NO: 8; and (ii) amino acid residues 1-23 of SEQ ID NO: 9.