Patent ID: 7771954

Claim:
A method for determining if a patient should be treated with a therapeutic agent targeted at treating cardiovascular disease, comprising: determining total protein bound or total free levels or both of one or more myeloperoxidase (MPO)-generated amino acids in a bodily sample of blood, serum, plasma, or urine from the patient, wherein the MPO-generated amino acids are selected from homocitrulline, methionine sulphoxide, nitrotyrosine, chlorotyrosine, and dityrosine, wherein at least one of the one or more MPO-generated amino acids is homocitrulline, comparing the levels of said one or more MPO-generated amino acids in the patient's bodily sample with a predetermined value, and determining that the patient should be treated with the therapeutic agent targeted at treating cardiovascular disease if the levels of said one or more MPO-generated amino acid in the patient's bodily sample is higher than the predetermined value.