Patent ID: 6933105

Claim:
A method for determining whether a test compound is a candidate compound for modulating the drug resistance of an eukaryotic cell, the method comprising: a) determining the level of expression of a gene encoding a polypeptide comprising the amino acid sequence encoded by the nucleotide sequence of SEQ ID NO:1 in an eukaryotic cell in the presence of a test compound, wherein the gene is endogenous to the eukaryotic cell; b) determining the level of expression of the gene in the eukaryotic cell in the absence of the test compound; and c) identifying the test compound as a candidate modulator of drug resistance of the eukaryotic cell if the level of expression of the gene in the eukaryotic cell in the presence of the test compound differs from the level of expression of the gene in the eukaryotic cell in the absence of the test compound.