Patent ID: 7662843

Claim:
A method for inhibiting MIF activity, comprising administering to a subject an effective amount of a compound of Formula I, wherein Formula I is: wherein: R 1-4 are, independently, R, halo, N 3 , CN, OH, NRR′, or SH; R and R′ are, independently, H or C 1-6 alkyl; X is R, halo, N 3 , CN, OR, NRR′, SH, ═O, ═CH 2 , or A; A is an unsubstituted aromatic ring, or an aromatic ring substituted with at least one member selected from the group consisting of R, halo, N 3 , CN, OH, NRR′ and SH; Y is R, NRR′, NRR″ or (CH 2 ) n −A; Z is R, OR, OR″, NRR′, NRR″, or A; R″ is a saturated or unsaturated, straight or branched chain C 2 -C 18 ; and n is 0 or 1.