Patent ID: 8557602

Claim:
A method for detecting intrahepatic cholangiocarcinoma in a subject undergoing testing or screening for liver carcinoma, the method comprising: a) contacting a clinical specimen obtained from the subject with Wisteria floribunda Agglutinin (WFA) lectin, under conditions in which the WFA lectin specifically binds a WFA-binding glycoprotein expressed by intrahepatic cholangiocarcinoma cells to form a WFA lectin-glycoprotein complex, wherein the WFA-binding glycoprotein is a cancer marker specific for intrahepatic cholangiocarcinoma and wherein one or more antibodies obtained using MUCI, CA125, or maspin as antigens recognize and bind to the WFA-binding glycoprotein; and b) detecting the presence of the WFA lectin-binding glycoprotein complex, thereby detecting intrahepatic cholangiocarcinoma in the subject.