Patent ID: 8426361

Claim:
A PPF polypeptide comprising an amino acid sequence of Formula (VII) (SEQ ID NO: 482): Xaa 1 Xaa 2 Pro Xaa 4 Pro Xaa 6 His Pro Xaa 9 Xaa 10 Xaa 11 Xaa 12 Xaa 13 Xaa 14 Xaa 15 Xaa 16 Xaa 17 Ala Xaa 19 Tyr Xaa 21 Xaa 22 Xaa 23 Leu Xaa 25 Xaa 26 Xaa 27 Xaa 28 Xaa 29 Xaa 30 Xaa 31 Thr Arg Gln Arg Tyr wherein: Xaa 1 is Tyr or absent; Xaa 2 is Ile, Pro, or absent; Xaa 4 is Lys, BH-modified Lys, Ala, Ser, or Arg; Xaa 6 is Glu, Gln, Ala, Asn, Asp, or Val; Xaa 9 is Gly or Ala; Xaa 10 is Glu, Ala, Asp, Asn, Gln, Gly, Pro, or Aib; Xaa 11 is Glu, Ala, Asp, Asn, Gln, Gly, Pro, or Aib; Xaa 12 is Ala or Pro; Xaa 13 is Ser or Pro; Xaa 14 is Pro, Ala, or Ser; Xaa 15 is Glu, Ala, Asp, Asn, Gln, Gly, Pro, or Aib; Xaa 16 is Glu or Asp; Xaa 17 is Leu or Ile; Xaa 19 is Arg, Lys, BH-modified Lys, Gln, or N(Me)Ala; Xaa 21 is Tyr, Ala, Phe, Lys, or BH-modified Lys; Xaa 22 is Ala or Ser; Xaa 23 is Ser, Ala, or Asp; Xaa 25 is Arg, Lys or BH-modified Lys; Xaa 26 is His, Ala, or Arg; Xaa 27 is Tyr, or Phe; Xaa 28 is Leu or Ile; Xaa 29 is Asn, or Gln; Xaa 30 is Leu or Met; and Xaa 31 is Val, Ile, or Leu.