Patent ID: 6872711

Claim:
A compound of formula (I): wherein X 1 , X 2 , X 3 , X 4 and X 5 are independently hydrogen, hydroxy, hydroxymethyl, C 1 -C 2 alkoxymethyl, a straight or branched C 1 -C 8 alkyl group, a straight or branched C 1 -C 8 alkoxy group; or X 2 may be combined with X 3 or X 4 may be combined with X 5 to form a 5- to 6-membered alkylidenedioxy ring optionally substituted with C 1 -C 4 alkyl groups; or X 4 may be combined with X 5 to form a 5- to 6-membered alkylidene ring optionally substituted with C 1 -C 4 alkyl groups; R 1 and R 2 are independently hydrogen or a straight or branched C 1 -C 6 alkyl group; B is CH 2 , CH 2 —CH 2 or CH═CH; n is zero or 1; Z 0 is H, a straight or branched C 1 -C 4 alkyl group, an acyl group R 3 —CO where R 3 is an alkyl group from 1 to 4 carbon atoms, a C 1 -C 4 perfluoroalkyl group; Z 1 , Z 2 are independently hydrogen, chloro, bromo, fluoro, a straight or branched C 1 -C 4 alkyl group; m is zero to 4; Het is an optionally substituted heteroaryl group comprising at least one nitrogen atom; or a pharmaceutically acceptable salt thereof.