Patent ID: 7473779

Claim:
A compound of the fommia (I′) wherein A is R 18 , R 19 and R 20 are independently selected from the group consisting of hydrogen, —OH, alkyl or alkoxy of 1 to 6 carbon atoms, R 21 and R 22 are independently selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms, or R 21 and R 22 form together with the nitrogen atom an optionally substituted heterocycle having 4 to 7 members and 1 to 3 heteroatoms including the already present nitrogon atom, the additional heteroatoms being-independently selected from the group consisting of O, N or furthermore R 21 is selected from the group consisting of alkylsulfonyl, alkylsulfoxide and alkylcarbonyl and then R 22 is hydrogen, B is thiophenyl, X is selected from the group consisting of a bond or —CO—NR 36 —, Y is selected from the group consisting of a bond, —(CH 2 ) n —, —(CH 2 ) r -Q-(CH 2 ) s — and thiazolidine, Q is selected from the group consisting of pinerazine, homopiperazine, 2-methylpiperazine, 2,5-dimethylpiperazine, piperidine, 1,2,3,6-tetrahydropyridine, pyrrolidine, azetidine, thiazolidine and a saturated carbon ring having 3 to 7 members, Φ is —(CH 2 ) p —NR 37 —(CH 2 ) q —, R 36 and R 37 are independently selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and —CO—R 38 , R 38 is alkyl or alkoxy of 1 to 6 carbon atoms, R 39 is hydrogen, m, n, p, q, r and s are independently integers from 0 to 6, and its pharmaceutically acceptable salts.