Patent ID: 7264810

Claim:
A composition comprising: (a) a non-natural molecular scaffold comprising: (i) a core particle comprising a virus-like particle of an RNA bacteriophage; and (ii) an organizer comprising at least one first attachment site, wherein said organizer is connected to said core particle by at least one covalent bond; and wherein said first attachment site is not a sulfhydryl group; and (b) an antigen or antigenic determinant with at least one second attachment site, wherein said antigen or antigenic determinant is at least one self antigen, a peptide thereof, or fragment thereof, wherein said self antigen is not amyloid β or a peptide of fragment thereof; wherein said second attachment site is capable of association through at least one non-peptide bond to said first attachment site; and wherein said antigen or antigenic determinant and said scaffold interact through said association to form an ordered and repetitive antigen array.