Patent ID: 7829580

Claim:
A compound having the general formula (I) shown below, wherein, R 1 represents a hydrogen atom, a C1-C6 alkyl group which may be substituted (said substituent group represents a halogen atom or a C1-C6 alkoxy group), a C3-C6 cycloalkyl group which may be substituted (said substituent group represents a halogen atom or a C1-C6 alkoxy group), a C1-C6 alkoxy group which may be substituted (said substituent group represents a halogen atom or a C1-C6 alkoxy group) or a C6-C10 aryl group which may be substituted (said substituent group represents a halogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group, a cyano group or a nitro group); R 2 represents a hydrogen atom, a C1-C7 alkanoyl group, a C7-C11 arylcarbonyl group, a group of formula R 4 —(CH 2 ) l —CO— (wherein R 4 represents a C1-C6 alkoxy group, an amino group, a C1-C6 alkylamino group, a di-(C1-C6 alkyl)amino group or a carboxyl group, and l represents an integer of from 0 to 4), a C6-C10 arylsulfonyl group, a C7-C16 alkylarylsulfonyl group, a C1-C6 alkylsulfanyl group or a C1-C6 alkylsulfanyl group substituted with 1 or 2 substituents selected from a group consisting of an amino group, a carboxyl group, a C1-C6 acylamino group and a C2-C7 alkoxycarbonyl group; R 3 represents a C6-C10 aryl group, a C6-C10 aryl group substituted with from 1 to 5 substituents selected from <Substituent group α>, a heteroaryl group or a heteroaryl group substituted with from 1 to 5 substituents selected from <Substituent group α>; X 1 , X 2 , X 3 , X 4 and X 5 represent independently a hydrogen atom, a halogen atom, an amino group, a carboxyl group, a carbamoyl group, a cyano group, a nitro group, a C1-C6 alkyl group, a halogeno C1-C6 alkyl group, a C1-C6 alkoxy group or a halogeno C1-C6 alkoxy group; n represents an integer of from 0 to 2; and <Substituent group α> is defined by: a halogen atom, an amino group, a carboxyl group, a carbamoyl group, a cyano group, a nitro group, a C1-C6 alkyl group, a halogeno C1-C6 alkyl group, a C1-C6 alkyl group substituted with heteroaryl group(s), a C1-C6 alkoxy group, a halogeno C1-C6 alkoxy group, a hydroxy C1-C6 alkyl group, a C2-C12 alkoxyalkyl group, a C2-C7 alkanoyl group, a C4-C7 cycloalkylcarbonyl group, a C1-C6 alkylamino group, a di-(C1-C6 alkyl)amino group, a C2-C7 alkylcarbamoyl group, a di-(C1-C6 alkyl)carbamoyl group, a group of formula R 5 —CO—CHR 6 —(CH 2 ) m — (wherein R 5 represents a hydroxyl group, an amino group, a C1-C6 alkyl group, a C1-C6 alkylamino group, a di-(C1-C6 alkyl)amino group, a hydroxyamino group, a C1-C6 alkoxyamino group or a C1-C6 alkoxy group; R 6 represents a hydrogen atom, a C1-C6 alkyl group, a C2-C7 carboxyalkyl group or a C3-C13 alkoxycarbonylalkyl group; and m represents an integer of from 0 to 5) and a sulfamoyl C1-C6 alkyl group, or pharmacologically acceptable salts thereof.