Patent ID: 7935722

Claim:
A compound of the formula: wherein, R 1 represents cyano, fluoro, chloro, bromo, methyl, CF 3 , CHF 2 , OCF 3 , OCHF 2 , CH═NOCH 3 , CH═NOCH 2 CH 3 , C(NOCH 3 )CH 3 , C(NOCH 2 CH 3 )CH 3 , COR 1a wherein R 1a represents hydrogen, hydroxyl, amino, methyl, methoxy, ethoxy, or CF 3 , OR 1b wherein R 1b represents methyl, ethyl, propyl, isopropyl, cyclopropyl, or cyclopropylmethyl; SO 2 R 1c wherein R 1c represents methyl; or NHCOR 1d wherein R 1d represents methoxy or ethoxy; R 2 represents hydrogen bromo, chloro, fluoro, methyl, or methoxy, or R 1 and R 2 together represent a group of the formula R 3 represents NHCOR 3a wherein R 3a represents independently at each occurrence methyl, ethyl, isopropyl, CH(C 2 H 5 ) 2 , CH(CH 3 )CH 2 CH 3 , CF 3 , methoxy, ethoxy, cyclopropyl, cyclobutyl, NH(CH 3 ), or N(CH 3 ) 2 ; or R 3 represents NHSO 2 R 3b , wherein R 3b represents independently at each occurrence cyclopropyl, NH(CH 3 ), N(CH 3 ) 2 , or N(CH 3 )OCH 3 ; and R 4 represents a phenyl group optionally substituted with a first subsitutent selected from the group consisting of amino, hydroxy, cyano, bromo, chloro, fluoro, nitro, methyl, methoxy, CF 3 , CHF 2 , OCF 3 , OCHF 2 , NH(C 2 H 5 ), N(CH 3 ) 2 , NHSO 2 CH 3 , and COOCH 3 and a second substituent selected from the group consisting of bromo, chloro, fluoro, and methyl, or a pharmaceutically acceptable salt thereof.