Patent ID: 8796300

Claim:
A compound of formula (I): wherein: Z is CH or N; each W is independently NH, S, or O; n is 1 and m is 3; or n is 2 and m is 2; or n is 3 and m is 1; or n is 4 and m is 0; X is H, hydroxy, halo, cyano, nitro, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkanoyl, (C 1 -C 6 )alkanoyloxy, (C 1 -C 6 )alkoxycarbonyl, —NR a R b , —C(═O)NR a R b , or —NR a C(═O)—R c ; wherein each (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkanoyl, (C 1 -C 6 )alkanoyloxy, and (C 1 -C 6 )alkoxycarbonyl of X is optionally substituted with one or more groups independently selected from hydroxy, halo, cyano, nitro, (C 1 -C 3 )alkoxy, (C 1 -C 3 )alkanoyl, (C 1 -C 3 )alkanoyloxy, (C 1 -C 3 )alkoxycarbonyl, —NR a R b , —C(═O)NR a R b , and —NR a C(═O)—R c ; Y is H, hydroxy, halo, cyano, nitro, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkanoyl, (C 1 -C 6 )alkanoyloxy, (C 1 -C 6 )alkoxycarbonyl, —NR a R b , —C(═O)NR a R b , or —NR a C(═O)—R c ; wherein each (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkanoyl, (C 1 -C 6 )alkanoyloxy, and (C 1 -C 6 )alkoxycarbonyl of Y is optionally substituted with one or more groups independently selected from hydroxy, halo, cyano, nitro, (C 1 -C 3 )alkoxy, (C 1 -C 3 )alkanoyl, (C 1 -C 3 )alkanoyloxy, (C 1 -C 3 )alkoxycarbonyl, —NR a R b , —C(═O)NR a R b , and —NR a C(═O)—R c ; each R 1 is independently H or (C 1 -C 6 )alkyl wherein any (C 1 -C 6 )alkyl of R 1 is optionally is optionally substituted with one or more groups independently selected from hydroxy, halo, cyano, nitro, (C 1 -C 3 )alkoxy, (C 1 -C 3 )alkanoyl, (C 1 -C 3 )alkanoyl oxy, (C 1 -C 3 )alkoxycarbonyl, —NR a1 R b1 , —C(═O)NR a1 R b1 , and —NR a1 C(═O)—R c1 ; each R a and R b is independently H, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyl, or aryl(C 1 -C 6 )alkyl; or R a and R b together with the nitrogen to which they are attached form an N-linked heterocycle containing from 3 to 10 atoms that is optionally substituted with one or more oxo; each R c is (C 1 -C 3 )haloalkyl; each R a1 and R b1 is independently H, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyl, or aryl(C 1 -C 6 )alkyl; or R a1 and R b1 together with the nitrogen to which they are attached form an N-linked heterocycle containing from 3 to 10 atoms that is optionally substituted with one or more oxo; each R c1 is halo(C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy or aryl(C 1 -C 6 )alkoxy; and wherein -u-d-v- is selected from: or a salt thereof.