Patent ID: 7683073

Claim:
An isoquinoline-1,3,4-trione compound represented having the following structural formula: wherein, the substituent R 1 is optionally selected from the group consisting of; alkyl; hydroxyl; alkyl substituted by the groups including halogen, alkoxyl or hydroxyl; alkoxyl or alkylamino substituted by the groups including halogen, alkoxyl or hydroxyl; C 2 -C 6 alkenyl substituted by oxygen or amine; C 3 -C 6 cycloalkyl; substituted aryl; benzyl; alkanoyl; alkanoyl substituted by the groups including halogen, alkoxyl or hydroxyl; C 2 -C 6 enoyl; C 3 -C 6 cycloalkanoyl; tert-butoxycarbonyl; benzoyl; benzoyl substituted by one, two or three groups including alkylamino; benzylacyl; benzylacyl substituted by one, two or three groups including alkylamino; thienoyl; adamantylcarbonyl; mandeloyl; alkoxyl; alkylamino; cycloalkoxyl; cycloalkylamino; amino; acylamino; alkyloxycarbonyl; cycloalkoxycarbonyl; alkanoyloxy; alkanoylamino; cycloalkyanoyloxy; cycloalkanoylamino; ureido; urenylene; alkanoyl; nitro; carboxyl; and substituent R 3 is optionally selected from the group consisting of H; alkyl; hydroxyl; alkyl substituted by the groups including halogen, alkoxyl or hydroxyl; alkoxyl or alkylamino substituted by the groups including halogen, alkoxyl or hydroxyl; C 2 -C 6 alkenyl substituted by oxygen or amine; C 3 -C 6 cycloalkyl; substituted aryl; benzyl; alkanoyl; alkanoyl substituted by the groups including halogen, alkoxyl or hydroxyl; C 2 -C 6 enoyl; C 3 -C 6 cycloalkanoyl; tert-butoxycarbonyl; benzoyl; benzoyl substituted by one, two or three groups including alkylamino; benzylacryl; benzylacrylcarbonyl substituted by one, two or three groups including alkylamino; thienoyl; adamantylcarbonyl; mandeloyl; alkoxyl; alkylamino; cycloalkoxyl; cycloalkylamino; amino; acylamino; alkyloxycarbonyl; cycloalkoxycarbonyl; alkanoyloxy; alkanoylamino; cycloalkyanoyloxy; cycloalkanoylamino; ureido; urenylene; alkanoyl; nitro; and carboxyl; Z is CH 2 , O or NH; W is O or H 2 ; n=1, 2, 3, 4, or 5. X is CH 2 , NH, O, or S; and Y is CH, or N.