Patent ID: 8679853

Claim:
A method, comprising: depositing a reagent on a base substrate; laser welding together the base substrate and a cover layer to form a sample-receiving chamber of a biosensor that contains the reagent, wherein no reagent is deposited where the layers are laser welded together; providing continuous webs of the base substrate and the cover layer; wherein said laser welding includes laser welding together the continuous webs of the base substrate and the cover layer to form a laminate, wherein the laminate includes multiple sample-receiving chambers containing the reagent; rotating a rotary-type mask as the continuous webs of the base substrate and the cover layer move thereby, wherein the rotary-type mask includes a plurality of mask apertures that form laser welding patterns for said laser welding; wherein said laser welding includes shining a laser beam through at least one of the mask apertures to form a laser weld in the shape of one of the laser welding patterns between the continuous webs; wherein one of the base substrate and the cover layer is more transparent than the other; and wherein said laser welding includes laser welding through the one that is more transparent by directing a laser beam through the one that is more transparent.