Patent ID: 8293053

Claim:
A method for making an active microfluidic device including at least one planar substrate and a deformable membrane, comprising the steps of: providing a planar microfluidic substrate having a surface including at least one microfeature; providing a deformable membrane suitable to cover at least a portion of the surface including the at least one microfeature; and, in the following order: contacting a non-deformed portion of the membrane with the at least the portion of the surface including the at least one microfeature to cover the at least the portion of the surface including the at least one microfeature; deforming at least a portion of the membrane covering the at least one microfeature out of the plane of the substrate; applying a thermally-activatable bonding agent to an interface between the substrate and the non-deformed portion of the membrane; and thermally activating the bonding agent.