Patent ID: 8507502

Claim:
A compound of formula (I): Wherein the compound is a furo[2,3-d]pyrimidine compound X is N; Y is O, S, or NR 2 , in which R 2 is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; A is alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, halo, cyano, nitro, OR 3 , OC(O)R 3 , C(O)R 3 , C(O)OR 3 , C(O)NR 3 R 4 , NR 3 R 4 , NHC(O)R 3 , NHC(O)NR 3 R 4 , NHC(S)R 3 , NHC(O)OR 3 , SO 2 R 3 , SO 3 R 3 , or SO 2 NR 3 R 4 , in which each of R 3 and R 4 , independently, is H, alkyl, alkenyl, alkynyl, silyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl, R 3 and R 4 are optionally substituted, or R 3 and R 4 , together with the nitrogen atoms to which they are bonded, are heterocycloalkyl, heterocycloalkenyl, or heteroaryl; B is aryl or heteroaryl; each of m and n, independently, is 0, 1, or 2; and ring C is or in which R″, is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, halo, nitro, cyano, OR a , C(O)OR a , C(O)NR a R b , NR b C(O)R a , NHC(O)NR a R b , NR b C(S)R a , NHSO 2 R a , or NR a R b , in which each of R a and R b , independently, is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl, R a and R b are optionally substituted, or R a and R b , together with the nitrogen atoms to which they are bonded, are heterocycloalkyl, heterocycloalkenyl, or heteroaryl, R′ is NR b C(O)R a′ , R a′ being in which R 6 is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, C(O)R c , C(O)OR c , C(O)NR c R d , or CH 2 NR c R d , in which each of R c and R d , independently, is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl, or R c and R d , together with the nitrogen atoms to which they are bonded, are heterocycloalkyl, heterocycloalkenyl, or heteroaryl, and R 7 is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; Z is O, and W is CR 5 , in which R 5 is alkenyl, alkynyl, aryl substituted with OR a , or NR b C(O)R a , heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, halo, nitro, C(O)OR a , C(O)NR a R b , NR b C(O)R a , NHC(O)NR a R b , NR b C(S)R a , NHSO 2 R a , or NR a R b .