Patent ID: 8901085

Claim:
A compound of the formula (I): wherein R 1 is —C(O)R 8 ; R 8 is a 5- or 6-membered unsaturated heterocyclic ring comprising 1 to 3 heteroatoms selected from N and O, optionally substituted with one or more substituents selected from alkyl, alkoxy, amine, aminoalkyl, amidoalkyl, halo, hydroxy, trihaloalkyl, trihaloalkoxy, and phenyl, wherein the phenyl group is optionally substituted with 1 to 3 substituents selected from alkyl, alkoxy, hydroxy, halo, nitro, trihaloalkyl, and trihaloalkoxy; R 2 is an aromatic or aliphatic C 3 -C 8 cyclic group or C 3 -C 8 heterocyclic group comprising 1 to 3 heteroatoms selected from N and O, wherein the C 3 -C 8 cyclic group or C 3 -C 8 heterocyclic group is optionally substituted with one or more substituents selected from alkyl, amine, and hydroxy, or the cyclic group or heterocyclic group is fused with an optionally substituted aromatic or aliphatic C 3 -C 8 cyclic group or C 3 -C 8 heterocyclic group; R 3 is hydrogen or C 1 -C 6 alkyl; R 4 is hydrogen, C 1 -C 6 alkyl, aminoalkyl, or amidoalkyl; R 5 is a benzyl group optionally substituted with alkyl, aminoalkyl, alkoxy, C 4 — C 7 heterocycle, hydroxy, halo, nitro, dioxalane, trihaloalkyl, trihaloalkoxy or —C(O)NHCHR 9 R 10 ; R 9 is —C(O)NH 2 ; and R 10 is a C 2 -C 5 aminoalkyl; or R 4 and R 5 combined, together with the nitrogen to which they are attached, form piperidine, optionally substituted but not fused with a group selected from phenyl, benzyl, aminoaryl, amidoalkyl or a heterocycle, or piperidine is fused with an aromatic or aliphatic C 3 -C 8 heterocyclic group; wherein the phenyl, benzyl, aminoaryl, heterocycle or fused aromatic or aliphatic C 3 -C 8 heterocyclic group may be further substituted with 1 to 3 substituents selected from alkyl, alkylsulfonyl, alkoxy, aminoalkyl, aminoaryl, amidoalkyl, arylamine, hydroxy, halo, nitro, oxo, optionally substituted phenyl, optionally substituted piperidine, dioxalane, trihaloalkyl, and trihaloalkoxy; or the fused aromatic or aliphatic C 3 -C 8 heterocyclic group is fused with an additional C 6 -C 10 cyclic or C 6 -C 10 heterocyclic group; R 6 is hydrogen or C 1 -C 6 alkyl; R 7 is C 1 -C 6 alkyl, amino, hydroxy, alkoxy, aminoalkyl, amidoalkyl, saturated or unsaturated cycloalkyl, or heterocycle; or a salt thereof.