Patent ID: 8765809

Claim:
A method of enhancing blood circulation, comprising topically administering, to a mammal in need thereof, an effective amount of one or more kinds of a compound represented by formula (I′) wherein X 1 is a methylene group, an ethylene group, a trimethylene group or a vinylene group, X 2 is a divalent group represented by formula A or B and R3 is a group represented by formula (IIIa') wherein Y is an ethylene group or a vinylene group, m and n are each an integer of 0 to 7, which satisfy m+n=0 to 8, and R1 and R2 are each independently a hydrogen atom, a methyl group or an ethyl group, provided that (3) when X 1 is a methylene group, then X 2 is not a divalent group represented by formula A, (4) when X 1 is a methylene group and X 2 is a divalent group represented by formula B, then R3 is not a straight chain alkyl group having a carbon number of 3 to 12; (5) when X 1 is a vinylene group and X 2 is a divalent group represented by formula (B), then R3 is not a straight chain alkyl group; and (6) when X i is a vinylene group, then X 2 is not a divalent group represented by formula A.