Patent ID: 8461185

Claim:
A compound of structural formula I: or a pharmaceutically acceptable salt and individual enantiomers and diastereomers thereof wherein: X is N and Y is CR 1 ; A represents a five membered heterocyclyl selected from the group consisting of (CH 2 ) n isoxazolyl, and (CH 2 ) n dihydro-isoxazolyl; R 1 represents H, C 1-6 alkyl, halogen, (CH 2 ) n CF 3 , C 3-10 cycloalkyl, CN, (CH 2 ) n O R 2 , (CH 2 ) n C 6-10 aryl, or C 1-6 alkoxy; said alkyl, cycloalkyl, and aryl optionally substituted with 1 to 3 groups of C 1-6 alkyl, halogen, hydroxyl, (CH 2 ) n CF 3 , or CN; R 2 represents H, C 1-6 alkyl; R 3 represents CR 2 R 4 R 5 ; one of R 4 and R 5 represents (CH 2 ) n pyridyl, and the other represents H, (CH 2 ) n OR 2 , CHF 2 , (CH 2 ) n C 6-10 aryl, C 3-10 cycloalkyl, C 1-6 alkoxy, or C 1-6 alkyl; said alkyl, pyridyl, cycloalkyl, and aryl optionally substituted with 1 to 3 groups of R a ; one of R 6 and R 7 represents (CH 2 ) n pyridyl, and the other represents hydrogen, C 1-6 alkyl, halogen, hydroxyl, (CH 2 ) n CF 3 , C 3-6 cycloalkyl, or (CH 2 ) n C 6-10 aryl, said aryl and pyridyl, optionally substituted with 1 to 3 groups of C 1-6 alkyl, halogen, (CH 2 ) n OR 2 , —C(R 2 ) 2 OR—C(O)R 2 , (CH 2 ) n CF 3 , or CN; R a represents C 1-6 alkyl, halogen, —OR 2 , hydroxyl, (CH 2 ) n CF 3 , —O—, C 3-6 cycloalkyl, or C 6-10 aryl, said aryl optionally substituted with 1 to 3 groups of C 1-6 alkyl, halogen, hydroxyl, (CH 2 ) n CF 3 , or CN; and n represents 0 to 4.