Patent ID: 7078522

Claim:
A pyridopyrimidine or a naphthyridine compound of the formula (I): wherein R 1 is a nitrogen-containing heterocyclic group which is optionally substituted by (i) a lower alkyl group optionally substituted by a group selected from the group consisting of a hydroxy group, a halogen atom and a lower alkoxy group; (ii) an amino group which is optionally substituted by a group selected from the group consisting of a lower alkyl group optionally substituted by a heteroaryl group, a lower alkyl group optionally substituted by an aryl group, and a lower alkoxy group; or (iii) an alkoxy group which is optionally substituted by (1) an aryl group optionally substituted by a group selected from the group consisting of a hydroxy group, a halogen atom and a lower alkoxy group, or (2) a lower alkyl group optionally substituted by a heteroaryl group which may be optionally substituted by a group selected from the group consisting of a hydroxy group, a halogen atom and a lower alkoxy group; R 2 is a hydrogen atom or a lower alkyl group; R 3 is (i) a hydrogen atom; (ii) a lower alkyl group which is optionally substituted by a nitrogen-containing heterocyclic group; or (iii) a heteroaryl group which is optionally substituted by a group selected from the group consisting of a hydroxy group, a halogen atom and a lower alkoxy group; R 4 is (i) a hydrogen atom; (ii) a lower alkyl group; (iii) a carboxyl group esterified with a lower alkyl group; (iv) a carboxyl group amidated with a lower alkyl-substituted amino group which may be optionally substituted by a hydroxy group or a 5- to 6-membered nitrogen-containing heteromonocyclic group optionally substituted by a lower alkyl group; or (v) a carboxyl group amidated with a 5- to 6-membered nitrogen-containing heteromonocyclic group optionally substituted by a lower alkyl group; R 5 is a lower alkyl group which may be optionally substituted by a group selected from the group consisting of (i) an aryl group optionally substituted by a group selected from the group consisting of a hydroxy group, a halogen atom and a lower alkoxy group; (ii) a heteroaryl group optionally substituted by a group selected from the group consisting of a hydroxy group, a halogen atom and a lower alkoxy group; and (iii) a di-lower alkylamino group; and X is a group of the formula: ═CH— and Y is a nitrogen atom, or X and Y are both nitrogen atoms, or a pharmaceutically acceptable salt thereof.