Patent ID: 7816333

Claim:
A method for the treatment of pain, psoriasis, an inflammatory disorder of the skin, an infectious disease of the skin, skin cancer, Lyme disease, influenza virus, cytomegalovirus, herpes virus, herpes simplex virus, papilloma virus, Epstein Barr virus or HIV, which method comprises administering to a mammal in need of such treatment a pharmaceutically effective amount of an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of said nucleoside units is a structure of the formula (2): wherein: A represents a methylene group; and B is selected from the group consisting of an unsubstituted purin-9-yl group, an unsubstituted 2-oxo-pyrimidin-1-yl group and a purin-9-yl group substituted with at least one substituent α, said substituent α being selected from the group consisting of an unprotected hydroxyl group, a protected hydroxyl group, an alkoxy group having from 1 to 4 carbon atoms, an unprotected mercapto group, a protected mercapto group, an alkylthio group having from 1 to 4 carbon atoms, an unprotected amino group, a protected amino group, an amino group substituted by an alkyl group having from 1 to 4 carbon atoms, an alkyl group having from 1 to 4 carbon atoms, and a halogen atom; or a pharmacologically acceptable salt thereof.