Patent ID: 6903114

Claim:
A compound of formula I,: wherein the two OH— substituents in the phenyl moiety are in a position ortho to one another and R 1 is in a position ortho to one of the hydroxy groups; and wherein “A” is a fused ring moiety selected from a benzo ring and a 6-membered heteroaromatic ring which contains one or two N heteroatoms; t is 1,2,3 or 4; R 1 is NO 2 , CN, CHO or CF 3 ; and each R 2 is selected independently from OH, halogen, NO 2 , SH, NH 2 , (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 1 -C 6 )alkoxy, OH—(C 1 -C 6 )alkyl, NH 2 —(C 1 -C 6 )alkyl, halo-(C 1 -C 6 )alkyl, mono- or di(C 1 -C 6 )alkylamino, SO 2 R 4 , (C 1 -C 20 )alkyl-CO—, halo-(C 1 -C 6 )alkyl, -CO—, phenyl-N═N— optionally substituted with one to three substituents R 6 , —(Y) n —(Y) n —(B) m —R 5 ; R 3 is H, NO 2, CN, CHO, halogen, CF 3 or CH 3 ; and R 4 is (C 1 -C 6 )alkyl, NH 2 , OH or mono- or di(C 1 -C 6 )alkylamino; m is 0 or 1; n is 1; Y is —CO— or —CHOH—; B is (C 1 -C 6 )alkylene or (C 2 -C 6 )alkenylene; R 5 is phenyl, naphthyl, (C 3 -C 7 )cycloalkyl or 5- to 10-membered heterocyclyl with one to four heteroatoms each selected independently from N, O and S, wherein the said phenyl, naphthyl, (C 3 -C 7 )cycloalkyl or 5- to 10-membered heterocyclyl is optionally substituted with one to five substituents R 6 or R 5 is each R 6 is selected independently from OH, halogen, COOH, 5-tetrazolyl, NO 2 , SH, NH 2 , CN, CHO, ═O, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, halo-(C 1 -C 6 )alkyl, mono- or di(C 1 -C 6 )alkylamino, CO—(C 1 -C 6 )alkyl, CO—NH 2 , mono- or di(C 1 -C 6 )alkylamino-CO—, NHOH, CONHOH and SO 2 R 4 ; or a pharmaceutically acceptable salt or pharmaceutically acceptable ester or pharmaceutically acceptable amide thereof.