Patent ID: 8791161

Claim:
A compound having Formula I, its enantiomers, diastereoisomers, hydrates, solvates, and individual isomers, tautomers or a pharmaceutically acceptable salt thereof: wherein: R 1 is H; R 2 is substituted or unsubstituted C 1-6 alkyl, substituted or unsubstituted C 3-8 cycloalkyl; R 5 is —S—, —S(O)—, or —S(O) 2 —; R 6 is 4-chloro-3-trifluoromethyl-phenyl; R 17 is H, substituted or unsubstituted C 1-6 alkyl, halogen, substituted or unsubstituted —OC 1-6 alkyl, CN, C(O)R 19 , NR 20 R 21 or hydroxyl; R 18 is H, substituted or unsubstituted C 1-6 alkyl, halogen, substituted or unsubstituted —OC 1-6 alkyl, CN, C(O)R 22 , NR 23 R 24 or hydroxyl; R 7 is halogen, CN, substituted or unsubstituted —OC 1-6 alkyl, substituted or unsubstituted C 1-6 alkyl or is substituted or unsubstituted C 3-8 cycloalkyl; R 8 is H, substituted or unsubstituted C 1-6 alkyl, halogen, substituted or unsubstituted —OC 1-6 alkyl, or hydroxyl; R 19 is H, OH or substituted or unsubstituted C 1-6 alkyl; R 20 is H or substituted or unsubstituted C 1-6 alkyl; R 21 is H or substituted or unsubstituted C 1-6 alkyl; R 22 is H, OH or substituted or unsubstituted C 1-6 alkyl; R 23 is H or substituted or unsubstituted C 1-6 alkyl; R 24 is H or substituted or unsubstituted C 1-6 alkyl.