Patent ID: 7381540

Claim:
A method for lowering a reactivity on maltose in glucose measurement comprising a step of reacting modified pyrroloquinoline quinone dependent glucose dehydrogenase in the presence of at least one substance selected from the group consisting of succinic acid, malonic acid, glutaric acid, malic acid, phthalic acid, 2-ketoglutaric acid, 3,3-dimethylglutaric acid, pimeric acid, suberic acid, adipic acid, maleic acid, potassium chloride, ammonium chloride, diammonium hydrogen citrate, L-lysine, taurine, calcium glycerate, amino-n-butyric acid, sodium glycolate, sodium α-ketoglutarate, fumaric acid, glycine, glutamic acid, serine and citric acid, wherein the modified pyrroloquinoline quinone dependent glucose dehydrogenase consists of SEQ ID NO: 1 except that position 168 of SEQ ID NO: 1 and at least one position selected from the group consisting of positions 169, 170, 245, 342, and 351 of SEQ ID NO: 1 are substituted with another amino acid, and wherein a pH of 5.0 to 6.0 is maintained during the glucose measurement reaction.