Patent ID: 8399612

Claim:
A compound of formula (VII): wherein m is an integer of 1 to 50; R 1′ is hydrogen or is independently selected from a C 1-10 branched or straight chain alkyl group, C 5-12 heteroaryl group or C 6-12 aryl group optionally substituted with OR 13 , SR 13 , N(R 13 ) 2 , CO 2 R 13 , CON(R 13 ) 2 , SO 2 R 12 , SO 2 R 12 , phenyl, imidazolyl, indolyl, hydroxyphenyl or NR 13 C(═NR 13 )N(R 13 ) 2 ; R 2 is independently selected from a C 1-10 branched or straight chain alkyl group, C 6-12 heteroaryl group or C 5-12 aryl group, optionally substituted with OR 13 , SR 13 , N(R 13 ) 2 , CO 2 R 13 , CON(R 13 ) 2 , SO 2 R 12 , SO 2 R 12 , phenyl, imidazolyl, indolyl, hydroxyphenyl or NR 13 C(NR 13 )N(R 13 ) 2 ; R 5 is a C 5-12 aryl, C 5-12 heteroaryl or C 1-6 branched or straight chain alkyl optionally substituted with OR 13 , SR 13 , N(R 13 ) 2 , CO 2 R 13 , CON(R 13 ) 2 , phenyl, imidazolyl, indolyl, hydroxyphenyl or NR 13 C(═NR 13 )N(R 13 ) 2 or a linker for attachment of formula (VII) to a resin wherein the linker is selected from OR 13 , N(R 13 ) 2 , CO 2 R 13 , SR 13 or an alkyl group having 1 to 4 carbon atoms or a C 6 -C 12 aryl group, wherein the alkyl and/or aryl group can be substituted with one or more of OR 13 , N(R 13 ) 2 , CO 2 R 13 , SR 13 ; R 9 and R 10 are independently hydrogen or a group as defined for R 1′ ; or R 9 and R 10 can together from a 4 to 7 membered ring, optionally substituted with CO 2 R 13 , OR 13 , SR 13 , N(R 13 ) 2 , CO 2 R 13 , CON(R 13 ) 2 , C 1-10 alkyl or C 6-12 aryl, wherein said ring can be fully, partially or unsaturated, and wherein the ring may contain one or more heteroatoms selected from O, S or N; R 11 is hydrogen or an amino protecting group selected from at least one of a benzyloxycarbonyl group, a t-butoxycarbonyl group, a 2-(4-biphenylyl)-isopropoxycarbonyl group, a fluorenylmethoxycarbonyl group, a triphenylmethyl group or a 2-nitrophenylsulphenyl group; wherein X is O or S; R 12 is hydrogen, C 1-6 alkyl, C 6-12 aryl or N(R 13 ) 2 , wherein each occurrence of R 13 is independently hydrogen, C 1-6 alkyl or C 6-12 aryl; and n is 1, 2 or 3.