Patent ID: 7601848

Claim:
3,4-disubstituted-1,2-dithiocyclohexane compounds of the formula wherein protecting-group-Y 1 is protecting-group-NH, protecting-group-NR 4 , protecting-group-O, CONH-protecting-group, protecting-group-OOC, protecting -group-S—S, —CH (protecting-group-O ) 2 , or protecting-group-S, wherein protecting-group is chosen from the group consisting of triphenylmethyl-, t-butoxycarbonyl-, benzyl-,2,4-dinitrophenyl-, 9-fluorenylmethoxycarbonyl-, allyloxycarbonyl-, benzyloxymethyl-, 4-azidobenzyloxycarbonyl-, acetamidomethyl-, 1-adamantyl-, 1-adamantyloxycarbonyl-, anisyl, benzamidomethyl-, biphenyldimethylsilyl-, 2,4-dimethylthiophenoxycarbonyl-, 1-methyl-1-(4-biphenyl)ethoxycarbonyl-, benzothiazole-2-sulfonyl-, t-butoxymethyl-, benzoyl-, benzyloxycarbonyl-, cyclohexan-1,2-diacetal-, cyclohexyl-, 2-(4,4-dimethyl -2,6-dioxocyclohexylidene)ethyl-, 1-methyl-1-(3,5-dimethoxyphenyl )ethoxycarbonyl-, diethylisopropylsilyl-, 1,3-dithianyl-2-methyl-, 2,4-dimethoxybenzyl-, dithianylmethoxycarbonyl-, dimethoxytrityl-, p,p′-dinitrobenzhydryl-, 2,4-dinitrophenyl-, 2,4-dimethylpent -3-yloxycarbonyl-, 2-(diphenylphosphino)ethyl-, 9-fluorenylmethyl-, levulinoyl-, p-methoxybenzensulfonyl-, 2,6-dimethoxy-4-methoxybenzensulfonyl-, monomethoxytrityl-, methoxyphenylsulfonyl-, mesitylensulfonyl-, o-nitrobenzyl-, 2-[2-(benzyloxy)ethyl]benzoyl-, 3-(3-pyridyl)allyloxycarbonyl-, 2,2,5,7,8-pentamethylchroman-6-sulfonyl-, pivaloyloxymethyl-, t-butyldimethylsilyl-, t-butyldiphenylsilyl-, 2,2,2-trichloro-1,1-dimethylethyl-, trifluoroacetyl-, triisobutylsilyl-, 2,4,6-trimethylbenzyl-, trimethoxybenzyl-, p-toluensulfonyl- or benzyloxycarbonyl-, Y 2 is —OH, —NH 2 , —NHR 3 , —NR 3 R 4 , —COOH, —COCl, —COOCO—R 6 , —CONH 2 , —CONHR 3 , —COOR 3 , —SO 3 H, —SO 3 Cl, —SH, —S—SR 3 , —CHO, —COR 3 , —C 2 H 3 O, halogen, —N 3 , —NH—NH 2 , —NCO, —NCS, wherein R 3 is alkyl, heteroalkyl, aryl, cycloalkyl or a protecting group, wherein R 3 in the groups Y 1 and Y 2 may be equal or different, R 4 is a protecting group, wherein R 4 in the groups Y 1 and Y 2 may be equal or different, and wherein R 4 and R 3 may be equal or different, R 6 is alkyl, heteroalkyl, aryl, or cycloalkyl, wherein R 6 in the groups Y 1 and Y 2 may be equal or different, wherein Y 2 may also be a group of the formula (II) or (III), wherein X 1 is halogen or substituted amine, X 2 is alkyl, alkoxy, aryloxy or a cyano derivative of alkyl, alkoxy, aryloxy, X 3 is halogen, amino group or oxygen and X 4 is alkyl, alkoxy, aryloxy or X 4 is H if X 3 is oxygen.