Patent ID: 8557809

Claim:
A compound of general Formula I: or a pharmaceutically acceptable salt thereof, wherein: R 10 and R 11 together with the N to which they are attached form a 4-8 membered heterocyclic ring optionally having an additional ring heteroatom selected from N and O, wherein the heterocyclic ring is optionally substituted with one or more R 9 groups; each R 9 is independently selected from halogen, (1-6C)alkyl, NR f R g , -(1-6C alkyl)NR h R i , OR j , (1-6C alkyl)OR k , C(O)NR m R n , C(O)O(1-6C alkyl), and -(1-6C alkyl)NR h C(O)O(1-6C alkyl); B is H, OR a , (1-6C alkyl)NR b R c , (1-6C alkyl)OH, NR b R c , or CH(OH)CH 2 OH; R 1 is H, F, Cl, Br, methyl, ethyl, cyclopropyl or CN; R 1a , R 2 , R 3 and R 4 are independently H, F, Cl, Br, methyl, ethyl, cyclopropyl or CN; R 5 and R 7 are independently H, F, Me or CN; R 6 is H, F, Me, Br, CN, cyclopropyl or phenyl; R a is H, (1-6C alkyl), -(1-6C alkyl)-O-(1-6C alkyl) or -(1-6C alkyl)-O-(3-6C cycloalkyl); each R b , R c , R d , R e , R f , R g , R h , R i , R j , R k , and R m is independently selected from H and (1-6C alkyl); and R n is H, (1-6C alkyl) or O-(1-6C alkyl).