Patent ID: 7135338

Claim:
A transformed host cell which comprises a DNA construct comprising a cloning vector which comprises: a) a sequence of a human mannose-binding lectin (MBL) coding region, said sequence being sufficient to express a recombinant MBL in said transformed host cell, b) an SV40 promoter DNA sequence operatively linked to said sequence of human MBL coding region, c) a sequence of nuclear matrix attachment region element of beta-globin gene sequence, d) an SV40 poly A, and e) a transcription termination sequence of a gastrin gene, said recombinant MBL exhibiting specific binding to pre S portion of Hepatitis B virus envelope protein and complement activation in the presence of MBL-binding glycosylated protein and serine proteases, wherein said transformed host cell is deposited to the International Depository Authority under the accession number KCTC 10472BP.