Patent ID: 7425546

Claim:
A method for the treatment of an immune-mediated gastrointestinal disorder or a non-IBD autoimmune disease, said method comprising: (a) administering azathioprine or 6-mercaptopurine to a subject having an immune-mediated gastrointestinal disorder or a non-IBD autoimmune disease; (b) determining a level of 6-thioguanine present in said subject from red blood cells; (c) indicating that said determined level of 6-thioguanine is associated with a higher likelihood of response when said determined level of 6-thioguanine is between about 230 pmol per 8×10 8 red blood cells and about 450 pmol per 8×10 8 red blood cells; and (d) considering said determined level of 6-thioguanine in the treatment of said subject.