Patent ID: 8680110

Claim:
A compound having the following formula (I) or a pharmacologically acceptable salt thereof: wherein each of R 1 and R 2 independently is hydrogen, a C 1-8 alkyl group, a C 2-8 alkenyl group, a C 1-8 alkoxy group, a C 1-8 alkyl group having one to three halogen atoms, a C 1-8 alkoxy group having one to three halogen atoms, an aralkyl group consisting of a C 6-10 aryl moiety and a C 1-3 alkylene moiety, a halogen atom, hydroxyl, nitro, cyano, amino, a C 1-8 alkylamino group, a C 2-8 dialkylamino group, a C 2-8 acylamino group, a C 2-8 acylamino group having one to three halogen atoms, a C 1-8 alkylsulfonylamino group, carboxyl, a C 2-8 acyl group, an alkoxycarbonyl group comprising a C 1-8 alkoxy moiety, carbamoyl, a C 1-8 alkylthio group, a C 1-8 alkylsulfinyl group, a C 1-8 alkylsulfonyl group, or sulfamoyl; R 3 is hydrogen, a C 1-8 alkyl group, a C 2-8 alkenyl group, a C 1-8 alkyl group having one to three halogen atoms, or an aralkyl group consisting of a C 6-10 aryl moiety and a C 1-3 alkylene moiety; R 4 is hydrogen, a C 1-8 alkyl group, a C 2-8 alkenyl group, a C 1-8 alkoxy group, a C 1-8 alkyl group having one to three halogen atoms, a C 1-8 alkoxy group having one to three halogen atoms, an aralkyl group consisting of a C 6-10 aryl moiety and a C 1-3 alkylene moiety, a C 1-8 alkyl group having hydroxyl, a halogen atom, hydroxyl, nitro, cyano, amino, a C 1-8 alkylamino group, a C 1-5 alkylamino group having one to five halogen atoms, a C 2-8 dialkylamino group, a C 2-8 acylamino group, a C 2-8 acylamino group having one to three halogen atoms, a C 1-8 alkylsulfonylamino group, benzenesulfonylamino optionally having one or more substituents, carboxyl, a C 2-8 acyl group, an alkoxycarbonyl group comprising a C 1-8 alkoxy moiety, carbamoyl, a C 1-8 alkylthio group, a C 1-8 alkylsulfinyl group, a C 1-8 alkylsulfonyl group, sulfamoyl, phenyl optionally having one or more substituents, or a heterocyclic group optionally having one or more substituents; the ring shown below is a five-membered to eight-membered ring optionally comprising one or two nitrogen atoms as the members of the ring, and being condensed with the benzene ring at the positions of 1 and 2 of the benzene ring; and the ring shown below is an aromatic ring selected from the group consisting of benzene ring, naphthalene ring, pyridine ring, pyrimidine ring, quinoline ring, indole ring, indoline ring, benzimidazole ring, pyrazole ring, indazole ring, benzisoxazole ring, and benzotriazole ring, provided that R 4 is neither hydrogen, a C 1-8 alkyl group, nor a halogen atom in the case that the ring shown below is benzene ring