Patent ID: 6974568

Claim:
A method of ameliorating cough in a subject comprising the local administration to the upper respiratory airways of the subject of a CB1 cannabinoid receptor agonist of formula I: wherein X is N—R 1 or O; R is a saturated or unsaturated, chiral or achiral, cyclic or acyclic, substituted or unsubstituted hydrocarbyl group, wherein the hydrocarbyl group has 11 to 29 carbon atoms; R 1 , R 3 and R 4 are selected independently from hydrogen, alkyl (C1-4), alkenyl (C2-4), alkynyl (C2-4), cycloalkyl (C3-6), or a hydroxyalkyl group with from 2 to 4 carbon atoms; R 2 is OH or O—CO-alkyl, where the alkyl group has from 1 to 4 carbon atoms; and n is selected from 2 to 4.