Patent ID: 7842707

Claim:
A compound of Formula I: wherein: X is NR 3 ; n is 1 or 2; A is adamantyl; R 1 is wherein: p and q are independently 0 or 1, wherein p+q=1; Y is CH 2 , CHF, CF 2 , O, or S(O) m ; W and Z are independently CH 2 , CHF, or CF 2 ; and wherein the ring formed by N, W, Y, Z and the carbon atoms to which they are attached is saturated or optionally contains one double bond; R 2 is R 4 —SO 2 —; R 5 —SO 2 —NH—C(O)—; or R 6 R 7 N—SO 2 —; R 3 is selected from the group consisting of H, alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocyclo, and heterocycloalkyl; R 4 is selected from the group consisting of: haloalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocyclo, and heterocycloalkyl; R 5 is selected from the group consisting of alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocyclo, and heterocycloalkyl; R 6 and R 7 are each independently selected from the group consisting of: H, alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocyclo, and heterocycloalkyl; or R 6 and R 7 together form C3-C7 alkylene; R 8 is H or cyano; m is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.