Patent ID: 8911804

Claim:
A method of inhibiting free radical formation and/or free radical activity, comprising administering to a subject an amount of a composition comprising a muscadine ( Vitis rotundifolia ) pomace solvent extract comprising a liquid bronze muscadine pomace extract combined with a liquid purple muscadine pomace extract to produce a liquid muscadine pomace extract, wherein a) the bronze muscadine pomace extract and the purple muscadine pomace extract are solvent extracts; b) the mixture of bronze muscadine pomace extract and purple muscadine pomace extract promotes solubility of ellagic acid in the muscadine pomace extract; c) the bronze muscadine pomace extract and the purple muscadine pomace extract are filtered and fermented extracts; and d) the muscadine pomace solvent extract has a polyphenol content of at least 2%; and resveratrol from a source other than muscadine with a minimum purity of at least 5% trans-resveratrol, wherein a ratio of muscadine pomace extract polyphenols to trans-resveratrol is in the range of 0.1/1 to 10/1 (weight to weight), wherein the composition has antioxidant activity and is in an amount sufficient to inhibit free radical formation and/or free radical activity.