Patent ID: 6844320

Claim:
A pharmaceutical composition comprising an admixture of effective amounts of: (a) a progestin and (b) a nitric oxide synthesis substrate, a nitric oxide donor or both, and, (c) at least one of a cyclooxygenase inhibitor, a PGI 2 -mimetic, a thromboxane (TXA 2 ) inhibitor, a compound possessing PGI 2 -agonistic and TXA 2 -inhibiting properties, a compound possessing TXA 2 -antagonistic and PGl 2 -mimetic activities, and a TXA 2 -antagonist, in amounts effective to ameliorate the symptoms of preeclampsia accompanied or unaccompanied by preterm labor in a pregnant female mammal, dysmenorrhea, or functional uterine bleeding or hemorrhaging.