Patent ID: 8436035

Claim:
A compound of formula (I): wherein R 1 , R 2 and R 6 are hydrogen; R 3 (C 1 -C 7 ) alkyl that is optionally substituted by one to four substituents selected from hydroxy, halogen, (C 1 -C 7 ) alkyl, (C 1 -C 7 ) alkoxy, (C 6 -C 10 ) aryloxy, 5-7 membered heterocycle, or 5-7 membered heteroaryl; R 4 and R 5 are independently hydrogen, (C 1 -C 7 ) alkyl, (C 6 -C 10 ) aryl, (C 6 -C 10 ) aryl-(C 1 -C 7 ) alkyl; or R 4 and R 5 taken together with the carbon atom to which they attach, form a 3-9 membered ring; R 7 and R 8 are independently hydrogen, (C 1 -C 7 ) alkoxy, (C 1 -C 7 ) alkyl, nitro, cyano, halogen, 5-7 membered heteroaryl, 5-7 membered heterocyclyl, (C 3 -C 7 ) cycloalkyl, 5-7 membered heterocyclyl-C(O)—, (C 5 -C 10 ) aryl optionally substituted by one to three substituents selected from halogen, or (Ra')(Rb')N—, wherein Ra' is hydrogen, or (C 1 -C 7 ) alkyl, Rb' is (C 1 -C 7 ) alkanoyl, or (C 1 -C 7 ) alkyl-SO 2 —; or Ra' and Rb' taken together with the attached nitrogen form a 5-7 membered ring; X is —C(O)—, and Y and W are each a bond; or a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers.