Patent ID: 8466291

Claim:
A compound of formula (I): wherein L is —(CH 2 ) 6 — or —(CH 2 ) 7 ; X is —O—, —NR a —, —NH—C(O)—, or deleted, in which R a is H, C 1-10 alkyl, aryl, heteroaryl, C 3-8 cycloalkyl, or C 1-7 heterocycloalkyl; R is C 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, aryl, heteroaryl, C 3-8 cycloalkyl, or C 1-7 heterocycloalkyl, optionally substituted with C 1-10 alkyl, aryl, heteroaryl, C 3-8 cycloalkyl, C 1-7 heterocycloalkyl, halo, —N 3 , —CN, nitro, amino, hydroxy, alkoxy, alkylthio, alkylcarbonyl, alkylcarbonyloxy, alkylcarbonylamino, or aminocarbonyl; Y is NR b , in which R b is H, C 1-10 alkyl, aryl, heteroaryl, C 3-8 cycloalkyl, or C 1-7 heterocycloalkyl; each of R 1 , R 2 and R 3 , independently, is H, C 1-10 alkyl, aryl, heteroaryl, C 3-8 cycloalkyl, C 1-7 heterocycloalkyl, or COR c , in which R c is C 1-10 alkyl, aryl, heteroaryl, C 3-8 cycloalkyl, or C 1-7 heterocycloalkyl; and R 4 is H, —O—(C 1 -C 10 alkyl), C 1 -C 10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, aryl, heteroaryl, C 3-8 cycloalkyl, or C 1-7 heterocycloalkyl.