Patent ID: 6852755

Claim:
A compound of Formula I: wherein: R 1 is —Cl, —Br, —I, —OSO 2 CH 3 , or —OSO 2 Ph; R 2 is —Cl, —Br, —I, —OSO 2 CH 3 , or —OSO 2 Ph; wherein Ph denotes a phenyl group which is optionally substituted with 1, 2, 3, 4 or 5 substituents independently selected from a C 1-4 alkyl group, —F, —Cl, —Br, —I, —CN, or —NO 2 ; R 1a is —H, a C 1-4 alkyl group, or a C 1-4 haloalkyl group; R 2a is —H, a C 1-4 alkyl group, or a C 1-4 haloalkyl group; R 1b is —H, a C 1-4 alkyl group, or a C 1-4 haloalkyl group; R 2b is —H, a C 1-4 alkyl group, or a C 1-4 haloalkyl group; R 3 is —F; R 4 is —F; R 5 is —H; R 7 is —H, —C(CH 3 ) 3 , or —CH 2 —CH═CH 2 ; Z is —CH 2 -T-W; T is —CH 2 —, —O—, —S—, —(S═O)—, or —(SO 2 )—; wherein the group —CH 2 —T—may optionally be substituted with 1 or 2 substituents, denoted Q 1 and Q 2 respectively, on carbon, wherein Q 1 and Q 2 are independently a C 1-4 alkyl group or a halogen; or, when Q 1 and Q 2 are bonded to adjacent carbon atoms, Q 1 and Q 2 together may form a C 3-4 alkylene radical optionally substituted with 1, 2, 3 or 4 substituents independently selected from C 1-4 alkyl groups and halogens; W is one of: (1) —COOH; (2) —(C═O)OR 8 ; (3) —(C═O)NR 9 R 9 ; (4) —SO 2 NHR 10 ; (5) —SO 2 OR 11 ; (6) —PO 3 R 11 R 11 ; (7) —CONH—SO 2 R 12 ; with the proviso that if T is —O—, —S—, —(S═O)—, or —(SO 2 )—, then W is not —COOH; wherein: R 8 is a C 1-6 alkyl group, a C 3-6 cycloalkyl group, or —CH 2 —CH═CH 2 ; R 9 is independently —H, a C 1-6 alkyl group, a C 3-6 cycloalkyl group, and wherein the C 3-6 cycloalkyl group may optionally carry a methyl group; R 10 is a C 1-6 alkyl group, —CH 2 —CH═CH 2 , a C 3-6 cycloalkyl group, or a C 1-4 haloalkyl group; and wherein the C 3-6 cycloalkyl group may optionally carry a methyl group; R 11 represents —H, a C 1-6 alkyl group, or a C 3-6 cycloalkyl group; R 12 is one of: (a) a C 3-7 cycloalkyl group; (b) a C 1-6 alkyl group, optionally substituted with one or more of: a phenyl group; a phenyl group with from 1 to 5 substituents selected from halogen, —NO 2 , —CF 3 , C 1-4 alkyl, C 1-4 alkoxy, —NH 2 , —NHCOCH 3 , —CONH 2 , —OCH 2 COOH, —NH(C 1-4 alkyl), —N(C 1-4 alkyl) 2 , —NHCOOC 1-4 alkyl, —OH, —COOH, —CN and —COOC 1-4 alkyl; a C 1-4 alkyl group; a C 1-4 haloalkyl group; or a halogen; and, (c) a C 1-6 perfluoroalkyl group.