Patent ID: 7265147

Claim:
A compound having the structure of Formula I: and its pharmaceutical acceptable salts, pharmaceutically acceptable enantiomers, diastereomers, N-oxides, wherein Ar represents an aryl or a heteroaryl ring having 1-2 hetero atoms selected from the group consisting of oxygen, sulphur and nitrogen atoms, the aryl or heteroaryl rings may be unsubstituted or substituted by one two three substituents independently selected from lower alkyl (C 1 -C 4 ), lower perhalo alkyl (C 1 -C 4 ), cyano, hydroxy, nitro, lower alkoxy (C 1 -C 4 ), lower perhaloalkoxy (C 1 -C 4 ), amino or lower alkyl (C 1 -C 4 ) amino or N-lower alkyl (C 1 -C 4 ) amino carbonyl; R 1 represents a hydrogen, hydroxy, hydroxy methyl, amino, alkoxy, carbamoyl or halogen; R 2 represents C 1 -C 4 alkyl, C 3 -C 7 cycloalkyl ring, a C 3 -C 7 cycloalkenyl ring, an aryl or a heteroaryl ring having 1 to 2 hetero atoms selected from a group consisting of oxygen, sulphur and nitrogen atoms; the aryl or a heteroaryl ring may be unsubstituted or substituted by one to three substituents independently selected from lower alkyl (C 1 -C 4 ), lower perhaloalkyl (C 1 -C 4 ), cyano, hydroxy, nitro, lower alkoxy carbonyl, halogen, lower alkoxy carbonyl halogen, lower alkoxy (C 1 -C 4 ), lower per haloalkoxy (C 1 -C 4 ), unsubstituted amino, lower alkylamino (C 1 -C 4 ) or N-lower alkyl (C 1 -C 4 ) aminocarbonyl; X represents an oxygen, sulphur, nitrogen or no atom; and R 3 , R 4 , R 5 , R 6 and R 7 independently represent, a hydrogen, lower alkyl (C 1 -C 4 ), lower perhaloalkyl (C 1 -C 4 ), cyano, hydroxyl, nitro, lower alkoxy carbonyl, halogen, lower alkoxy (C 1 -C 4 ), lower perhaloalkoxy (C 1 -C 4 ), amino or lower alkyl (C 1 -C 4 ) amino.