Patent ID: 7173048

Claim:
A compound of formula (I): wherein: R 1 is hydrogen, alkyl, halogen, formyl, hydroxyalkyl or trifluoromethyl; R 2 is hydrogen, alkyl, alkenyl, alkynyl, cyano or halogen; R 3 is hydrogen or alkyl; R 4 is hydrogen, alkyl, hydroxy or alkoxy; R 5 and R 6 are independently selected from hydrogen, alkyl, arylalkyl, heteroarylalkyl, hydroxyalkyl, alkoxycarbonyl, aryl and heteroaryl; A is aryl or heterocyclyl, wherein aryl and heterocyclyl are optionally substituted with one to three substituents independently selected from alkyl, halogen, amino, hydroxyalkyl, aryl, aryloxy, alkoxy, arylalkyl, arylalkenyl, alkoxycarbonylamino, aminocarbonyloxy, carboxy, alkoxycarbonyl, alkoxycarbonylalkyl, aminoalkyl, trifluoromethyl, arylalkylaminocarbonyl, alkoxycarbonylalkylaminocarbonyl, indolylalkylaminocarbonyl, morpholinylcarbonyl, aminocarbonyl, aminocarbonylalkyl, aminocarbonylalkoxy, alkoxycarbonylalkoxy, pyridinylalkylaminocarbonyl, alkyloxycarbonylalkylaryl, alkyloxycarbonylalkoxyaryl, carboxyalkylaryl, carboxyalkoxyaryl, aminocarbonylalkylaryl, aminocarbonylalkoxyaryl, aminocarbonylamino, aminocarbonyloxy, aminocarbonyloxyaryl, carboxyalkyl, carboxyalkoxy, cycloalkylaminocarbonyl, morpholinylcarbonyloxyaryl, morpholinylcarbonylaryl, arylalkoxyaryl, aminocarbonylaryl, pyrrolidinylcarbonyloxyaryl, pyrrolidinylcarbonylaryl, piperidinylcarbonylaryl, piperidinylcarbonyloxyaryl; hydroxyalkylaryl, hydroxy(carboxy)alkylaryl, hydroxy(alkoxycarbonyl)alkylaryl, hydroxy(aminocarbonyl)alkylaryl and pyridinyl; m is zero, 1, 2 or 3; n is zero or 1; p is zero, 1, 2 or 3; with the proviso that the sum of m, n and p is 1, 2, 3 or 4; and, wherein the compound is not 2-(1-benzyl-2,3-dihydro-1H-indol-5-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol; and, wherein the bond between the carbon atoms C a and C b is a carbon carbon single or double bond and in case the bond between C a and C b is a carbon carbon double bond R 3 and R 4 are absent; and pharmaceutically acceptable salts and pharmaceutically acceptable esters thereof.