Patent ID: 8748367

Claim:
A method of treatment of a brain injury, head trauma, an ischemic injury, asphyxia, a hypoxic injury, a traumatic injury, a stroke, and/or demyelinating disorder, associated with a pathological loss of nervous tissue, comprising administering to a patient in need thereof an effective amount of: (a) an antisecretory factor (AF) protein as shown in SEQ ID NO: 1, and/or (b) a fragment of the AF protein as shown in SEQ ID NO: 1, said fragment consisting of an amino acid sequence as shown in SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, or SEQ ID NO:6, and having a histidine at position 38, a serine at position 39, and a threonine at position 41 of SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, or SEQ ID NO:6; and/or (c) a fragment of the AF protein as shown in SEQ ID NO: 1, said fragment consisting of amino acid nos. 1-105 of SEQ ID NO:1; or a pharmaceutically acceptable salt thereof.