Patent ID: 7732638

Claim:
In an amidocarbonylation reaction which comprises reacting an aldehyde compound represented by the formula where R 1 is a hydrogen atom or a hydrocarbon group that may be substituted, with carbon monoxide and an amide compound represented by the formula where R 2 is a hydrocarbon group that may be substituted, to produce an amino acid compound represented by the formula where R 1 and R 2 are the same as above, the improvement wherein the reaction is conducted in the presence of a palladium-supported crosslinked polymer composition containing a palladium cluster having a major axis of 20 nm or less; wherein the said palladium-supported crosslinked polymer composition is one obtained by immobilizing palladium to a copolymer of monomers containing styrene compounds represented by formulas (1), (2) and (3) below Where R X and R Y are hydrogen atom or a substitution group of formula (1a), at least one of R X and R Y being a hydrogen atom, n is an integer of 0 to 6, m is an integer of 1 to 6, l is an integer of 0 to 10, R a is a hydrogen atom or a hydrocarbon group that may be substituted, R b is a hydrocarbon group that may be substituted, and R a and R b may combine with each other to form a lactam ring.