Patent ID: 7110817

Claim:
A system, comprising: a signal input to receive at least one cardiac signal indicative of cardiac events including at least one atrial event and one ventricular event; an event detector, coupled to the signal input, to detect the at least one atrial event and one ventricular event; a measurement module, coupled to the event detector, to measure an atrio-ventricular time interval (AV) between an atrial event and a ventricular event of the at least one atrial event and one ventricular event; and an atrio-ventricular delay (AVD) calculator coupled to the measurement module, the AVD calculator adapted to calculate an AVD using the AV and a predetermined equation relating the AV to an optimal AVD to provide a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, by delivering ventricular pacing pulses with the optimal AVD.