Patent ID: 8916561

Claim:
A pharmaceutical composition comprising a compound of Formula (IV): or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: Rz is tetrazolyl; R 1 is chosen from aryl and heteroaryl, either of which may be optionally substituted with one or more substituents chosen from hydrogen, halo, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, aryl, aralkyl, heterocyclyl, heteroaryl, heterarylalkyl, CN, alkoxy, alkylamino, dialkylamino, NHSO 2 R 12 , NHSO 2 NHR 12 , NHCOR 12 , NHCONHR 12 , CONHR 12 , CONR 12a R 12b , hydroxy, SO 2 R 12 , SO 2 NHR 12 , CF 3 , and OCF 3 ; R 5 and R 6 are independently chosen from hydrogen, C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 3 -C 7 heterocycloalkyl, aryl, heteroaryl, aralkyl, and heteroaralkyl, any of which may be optionally substituted by substituents chosen from lower alkyl, lower heteroalkyl, lower heterocycloalkyl, lower haloalkyl, lower perhaloalkyl, lower perhaloalkoxy, lower cycloalkyl, phenyl, aryl, aralkyl, lower alkoxy, lower haloalkoxy, carboxyl, cyano, hydrogen, halogen, hydroxy, amino, lower alkylamino, amido, nitro, sulfonate, and sulfonic acid; and R 12 , R 12a and R 12b are independently chosen from hydrogen, C 1 -C 6 alkyl, aryl, heteroaryl, aralkyl, CF 3 and heteroaralkyl, any of which may be optionally substituted by substituents chosen from lower alkyl, lower heteroalkyl, lower heterocycloalkyl, lower haloalkyl, lower perhaloalkyl, lower perhaloalkoxy, lower cycloalkyl, phenyl, aryl, aralkyl, lower alkoxy, lower haloalkoxy, carboxyl, cyano, hydrogen, halogen, hydroxy, amino, lower alkylamino, amido, nitro, sulfonate, and sulfonic acid; and a pharmaceutically acceptable carrier.