Patent ID: 8563044

Claim:
A microparticle dispersion liquid manufacturing method comprising: a dissolving step of dissolving a poorly soluble drug and a dispersion stabilizer in a volatile organic solvent, the poorly soluble drug having a water solubility of no more than 50 μg/mL at 25° C.; a fixing step of performing removal by evaporation of the organic solvent, contained in a solution obtained in the dissolving step, and fixing a residue, obtained by the organic solvent removal, on bottom surfaces of a plurality of recesses of a container; and an irradiating step of injecting water into an interior of the container after the fixing step such that the residue remains fixed on the bottom surfaces of the plurality of recesses of the container and is immersed in the water and, while making the water flow near an interface of the residue and the water in the interior of the container, irradiating light on the residue fixed on the bottom surfaces of the plurality of recesses of the container to manufacture a microparticle dispersion liquid having microparticles, containing the poorly soluble drug and the dispersion stabilizer, dispersed in water, the irradiating light being a laser having a wavelength of no less than 900 nm, wherein walls that form the bottom surfaces of the plurality of recesses of the container are made of a material that is transparent to the irradiating light and in the irradiating step, the light is irradiated from outside the bottom surfaces of the plurality of recesses of the container to propagate in the order of the bottom surfaces, the residues, and the water.