Patent ID: 8268321

Claim:
A composition for inducing mucosal immunity against an influenza virus by promoting the production of an IgA antibody against the virus in a local mucosal membrane, comprising an influenza virus split antigen and an antigen-drug vehicle which is a complex consisting of: a pulmonary surfactant protein B or a peptide consisting of the amino acid sequence of SEQ ID NO: 2, 7, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20, a pulmonary surfactant protein C or a peptide consisting of the amino acid sequence of SEQ ID NO: 4, 9, 21 or 6, and at least one lipid selected from the group consisting of phosphatidyl choline, dipalmitoyl phosphatidyl choline, phosphatidyl serine, dipalmitoyl glycerophosphocholine, diacyl glycerophosphoglycerol, phosphatidylglycerol, phosphatidyl inositol, phosphatidyl ethanolamine, phosphatidic acid, lauric acid, myristic acid, palmitic acid, stearic acid and oleic acid, wherein the composition is suitable for nasal administration.