Patent ID: 6846830

Claim:
A method of treating neurological disorders comprising administrating to a patient in need thereof an effective amount of a compound of the formula: where p is 0 to 4, q is 0 to 3; —A—E is attached to the 2 position of the naphthalene ring; —A— represents a group —CR 5 ═CR 6 —, or —COO—; R 5 and R 6 are each independently hydrogen or C 1 -C 6 alkyl, a substituted or unsubstituted phenyl, carboxy(C 1 -C 6 )alkyl or cyano; —E represents an unsubstituted pyridine or a substituted pyridine selected from the group consisting of or an unsubstituted didehydropiperidine; or a substituted didehydropiperidine selected from the group consisting of R 11 , R 12 , R 13 , R 17 , R 18 , R 19 , R 20 , R 21 , and R 22 , are each independently selected from C 1 -C 6 alkyl, especially methyl, C 1 -C 6 alkoxy, especially methoxy and ethoxy, carboxy, hydroxy, cyano, halogen, especially bromo, chloro and fluoro, trifluoromethyl, nitro, amino, C 1 -C 6 acylamino, C 1 -C 6 alkylthio, a substituted or unsubstituted phenyl, a substituted or unsubstituted benzyl and a substituted or unsubstituted phenoxy; R 1 and R 2 are each independently selected from C 1 -C 6 alkyl, hydroxy, C 1 -C 6 alkoxy, nitro, cyano, C 1 -C 6 alkylthio, halogen, trifluoromethyl, a substituted or unsubstituted phenyl, a substituted or unsubstituted benzyl or a group represented by —O—(CH 2 ) m′ —Y, in which Y represents C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, a substituted or unsubstituted phenyl, or C 1 -C 6 alkoxy; and m′ is 0 or 1; or a pharmaceutically acceptable salt or ester thereof, provided that when m′ represents 0, Y represents C 3 -C 6 cycloalkyl or a substituted or unsubstituted phenyl.