Patent ID: 8518430

Claim:
A method of injecting a solid pharmaceutical composition comprising: providing a solid pharmaceutical composition comprising: homogeneously mixing at least one therapeutic agent that constitutes at least 40% of the composition by weight with a binder that comprises at least one carbohydrate binding agent and constitutes at least 0.5% of the composition by weight, and at least one non-crystallization agent, so as to obtain an amorphous melt matrix, shaping the melt matrix to a needle-shaped geometry using a mold cavity such that the solid pharmaceutical composition is capable of penetrating the epidermis, cutis or mucosa of a patient by injection without the assistance of a hypodermic needle or trocar, cooling the amorphous melt matrix of the pharmaceutical composition to below the Tg of the binder, and removing the composition from the mold cavity, positioning an injection device comprising the solid composition adjacent to the epidermis, cutis or mucosa, and ejecting the solid composition from the device so as to inject the composition through the epidermis or mucosa.