Patent ID: 7230031

Claim:
A compound represented by general formula (I): wherein W is —O—; R 1 is a halogen atom, a lower alkyl group, a halo-lower alkyl group, a lower alkoxy group or —CN; R 2 is a hydrogen atom; R 3 is a hydroxy group or an acyloxy group; R 4 is a hydrogen atom, a halogen atom, an alkyl group, a halo-lower alkyl group, a substituted alkyl group, an aryl group, an aralkyl group, an alkoxy group, a substituted alkoxy group, an alkanoyl group, an aroyl group, —CONR 7 (R 8 ), —S(O) m R 9 or —SO 2 NR 7 (R 8 ), or R 3 and R 4 are bonded together to form —NH—CH═(R 9 )—; R 5 is a hydrogen atom, a halogen atom, an alkyl group, a substituted alkyl group, a hydroxy group, an alkoxy group, a substituted alkoxy group or an aralkyloxy group; m is 0 or an integer of 1 or 2; R 6 is a hydrogen atom or a lower alkyl group; each of R 7 and R 8 is independently a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, an aryl group or a heteroaryl group, or R 7 and R 8 , together with the nitrogen atom to which they are bonded, form a cyclic amine; R 9 is an alkyl group, a substituted alkyl group, a cycloalkyl group, an aryl group or a heteroaryl group; A represents —N(R 6 )CO—A 1 —COR 10 , R 10 is a hydroxy group, a lower alikoxy group or —NR 11 (R 12 ); each of R 11 and R 12 is independently a hydrogen atom, a lower alkyl group or a substituted lower alkyl group, or R 11 and R 12 , together with the nitrogen atom to which they are bonded, form a cyclic amine; A 1 is an alkylene group, an alkenylene group or a bond; a prodrug thereof, or a pharmaceutically acceptable salt thereof.