Patent ID: 8263610

Claim:
A compound having the formula I: or a salt thereof, wherein: R c1 is H, halogen, unsubstituted or substituted C 1 -C 6 alkyl, unsubstituted or substituted phenyl, or unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S; R c2 is H, or unsubstituted or substituted C 1 -C 6 alkyl; R c3 and R c4 are each independently H, unsubstituted or substituted C 1 -C 6 alkyl, or R c3 and R c4 , together with the atoms they attach to, form a 5-, 6- or 7-member ring which optionally comprises 1-4 heteroatoms selected from N, O and S and is optionally substituted; X 1 -X 2 is CHR c6 —NR y ; R c6 is H, unsubstituted or substituted C 1 -C 6 alkyl, or unsubstituted or substituted C 6 -C 10 aryl; R y is H, unsubstituted or substituted C 6 -C 10 aryl, unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C 3 -C 8 carbocycle, unsubstituted or substituted heterocycle comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S, —S(O) 2 R 1 , —C(O)R 1 , —C(O)OR 1 , —(CH 2 ) o R 1 , —C(═NH)NR 2 R 2 ′, —C(O)NR 2 R 2 ′, or —C(S)NR 2 R 2 ′; o is 0, 1, 2, 3, or 4; R 1 is H, unsubstituted or substituted C 1 -C 6 alkyl, or -T y1 -Q y1 ; R 2 and R 2 ′ are each independently H, unsubstituted or substituted C 1 -C 6 alkyl, -T y3 -Q y3 , or R 2 and R 2 ′, together with the atom they attach to, form a 5-, 6- or 7-member ring which comprises 1-4 heteroatoms selected from N, O and S and is optionally substituted; T y1 and T y3 are each independently a bond, or unsubstituted or substituted C 1 -C 6 alkyl linker; Q y1 is H, unsubstituted or substituted C 6 -C 10 aryl, unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C 3 -C 8 carbocycle, unsubstituted or substituted heterocycle comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S, —C(O)OR 21 , —C(O)R 21 , —C(O)NR 21 R 21 ′, or —NR 21 R 21 ′; Q y3 is H, unsubstituted or substituted C 6 -C 10 aryl, unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C 3 -C 8 carbocycle, unsubstituted or substituted heterocycle comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S, —C(O)OR 31 , —C(O)R 31 , —C(O)NR 31 R 31 ′, or —NR 31 R 31 ′; and R 21 , R 21 ′, R 31 and R 31 ′ are each independently H, unsubstituted or substituted C 1 -C 6 alkyl, unsubstituted or substituted C 6 -C 10 aryl, or unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member ring and 1-4 heteroatoms selected from N, O and S.