Patent ID: 8461107

Claim:
A compound of formula (I), or a pharmaceutical acceptable salt thereof: wherein: is selected from the group consisting of: each L is independently selected from the group consisting of N and CH, provided that the total number of L that are N is from 1 to 4, R 1 is selected from the group consisting of —CO 2 H, —CONHSO 2 (cyclopropyl) and —CONHSO 2 (1-methylcyclopropyl); R 2 is selected from the group consisting of ethyl and ethenyl; R 3 is selected from the group consisting of cyclopentyl, cyclohexyl, and —C(CH 3 ) 3 ; each R 4 is independently selected from the group consisting of halogen atoms, C 1 -C 4 alkoxy, C 1 -C 7 alkyl, C 2 -C 7 alkenyl, —CN, —CF 3 , —OCF 3 , SCH 3 , —SO 2 (CH 3 ), C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkoxy, C 1 -C 6 haloalkyl, phenyl, naphthyl and heteroaryl groups, wherein each said R 4 heteroaryl is selected from the group consisting of 5- and 6-membered aromatic rings having 1, 2 or 3 heteroatoms independently selected from N, O and S, and said R 4 heteroaryl is attached through a ring atom selected from C or N, each said R 4 phenyl, naphthyl and heteroaryl groups are substituted with 0 to 4 substituents independently selected from the group consisting of halogen atoms, —OR 5 , —SR 5 , —N(R 5 ) 2 , —N(C 1 -C 6 alkyl)O(C 1 -C 6 alkyl), C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, (C 1 -C 6 haloalkoxy), —NO 2 , —CN, —CF 3 , —SO 2 (C 1 -C 6 alkyl), —S(O)(C 1 -C 6 alkyl), —NR 5 SO 2 R 6 , SO 2 N(R 6 ) 2 , —NHCOOR 6 , —NHCOR 6 , —NHCONHR 6 , —CO 2 R 5 , —C(O)R 5 and —CON(R 5 ) 2 , and 2 adjacent substituents of said R 4 phenyl, naphthyl and heteroaryl groups may be taken together to form a 3- to 6-membered cyclic ring containing 0 to 3 heteroatoms independently selected from N, O and S; Y is selected from the group consisting of —C(O)—, —C(O)O— and —C(O)NH—; each R 5 is independently H or C 1 -C 6 alkyl; each R 6 is independently H, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyl(C 1 -C 5 )alkyl, aryl, aryl(C 1 -C 4 )alkyl, heteroaryl, heteroaryl(C 1 -C 4 alkyl), heterocyclyl, or heterocyclyl(C 1 -C 8 alkyl); M is selected from the group consisting of C 4 -C 7 alkylene and C 4 -C 7 alkenylene, wherein said M is substituted with 0 to 3 substituents independently selected C 1 -C 8 alkyl, provided that two adjacent substituents can together form a 3 to 6 membered ring.