Patent ID: 7763718

Claim:
An isolated nucleic acid molecule comprising a sequence encoding all or part of a TCR α chain, except the transmembrane domain thereof, wherein the all or part of the TCR α chain comprises a functional variable domain and at least a part of the constant domain of the TCR α chain, and wherein the all or part of the TCR α chain comprises a cysteine residue substituted for an amino acid selected from the group consisting of: (a) Thr 48 of exon 1 of TRAC*01 (amino acid residue 10 of SEQ ID NO:1); (b) Thr 45 of exon 1 of TRAC*01 (amino acid residue 10 of SEQ ID NO:2); (c) Tyr 10 of exon 1 of TRAC*01 (amino acid residue 10 of SEQ ID NO:3); and (d) Ser 15 of exon 1 of TRAC*01 (amino acid residue 10 of SEQ ID NO:4).