Patent ID: 7872017

Claim:
The compound of formula (I), or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, wherein n is 1, 2 or 3; A is N or N + —O − ; R is hydrogen, alkyl, cycloalkylalkyl and arylalkyl; L is selected from the group consisting of O, S, and —N(R a )—; Ar 1 is a pyridinylene group substituted with 0, 1, 2 or 3 substituents selected from the group consisting of acyl, acyloxy, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxyimino, alkoxysulfonyl, alkyl, alkylsulfonyl, alkynyl, amino, carboxy, cyano, formyl, haloalkoxy, haloalkyl, halo, hydroxy, hydroxyalkyl, mercapto, nitro, thioalkoxy,—NR g R j , (NR g R j )alkyl, (NR g R j )alkoxy, (NR g R j )carbonyl, and (NR g R j )sulfonyl, wherein R g and R j are each independently selected from the group consisting of hydrogen and alkyl; and Ar 2 is a bicyclic heteroaryl substituted with 0, 1, 2, or 3 substituents selected from the group consisting of alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxysulfonyl, alkyl, alkylcarbonyl, alkylcarbonyloxy, alkylsulfonyl, alkylthio, alkynyl, carboxy, cyano, formyl, haloalkoxy, haloalkyl, halo, hydroxy, hydroxyalkyl, mercapto, nitro, —NR g R j , (NR g R j )alkyl, (NR g R j )alkoxy, (NR g R j )carbonyl, and (NR g R j )sulfonyl, wherein R g and R j are each independently selected from the group consisting of hydrogen and alkyl; and R a is selected from the group consisting of hydrogen, alkyl and alkylcarbonyl.