Patent ID: 7507733

Claim:
A compound of the formula (I): wherein: R 1 is methyl, ethyl, cyclopropyl, cyclobutyl, isopropyl, tert.butyl, methoxymethyl, cyclopropylmethoxymethyl, 2-methyl-thiazolyl, morpholinylmethyl or phenyl; R 2 is hydrogen, alkyl or aryl; R 3 is hydrogen, alkyl or aryl; R 4 is phenyl, naphthyl, thiophenyl, quinolyl, piperidyl, morpholyl or thiomorpholyl, wherein phenyl, naphthyl, thiophenyl, quinolyl, piperidyl, morpholyl and thiomorpholyl are optionally substituted with one or more substituents independently selected from alkyl, cycloalkyl, halogen, alkoxy, cyano, trifluoromethyl, aryl, arylalkyl, aryloxy, oxazolyl, pyridinyl, pyrimidinyl, pyrazolyl, imidazolyl and thiazolyl; R 5 is hydrogen, alkyl, aralkyl, cycloalkylalkyl or aminocarbonylalkyl; and pharmaceutically acceptable salts and esters thereof; and, wherein N-(2,6-dimethyl-4-pyrimidinyl)-benzenesulfonamide; 2-chloro-N-(2-methyl-4-pyrimidinyl)-p-toluenesulfonamide; 2, 4, 5-trichloro-N-(2,6-dimethyl-4-pyrimidinyl)-benzenesulfonamide; and 4-chloro-N-(2,6-dimethyl-pyrimidin-4-yl)-benzenesulfonamide are excluded.