Patent ID: 8915875

Claim:
A medical device, useful for extracorporeally depleting unwanted substances from the blood of a patient, comprising a) a first line for carrying blood connectable to the patient, b) a second line for carrying blood connectable to the patient, c) a depletion unit connected with a liquid-tight seal to the first blood carrying line, d) an adsorbent contained in the depletion unit and containing i) a matrix of essentially spherical, unaggregated porous particles having pores with an average pore size of less than 1.5 μm and more than 0.1 μm and ii) a ligand covalently bonded to the matrix, which ligand binds to hepcidin with an affinity having a dissociation constant KD of less than 200 nM, e) a hemodialyzer, f) a controllable body fluid delivery device arranged in one or each of the first line and the second line for controlling flow of body fluid through the line and the depletion unit such that the first line continuously supplies body fluid from the patient to the depletion unit and the second line continuously supplies body fluid to the patient.