Patent ID: 7345048

Claim:
A compound of the formula: wherein R 1 is NH 2 ; R 2 is NH 2 ; R 3 is selected from hydrogen, alkyl, amino, hydroxy, alkoxy, and alkylamino; and R 4 is wherein R 8 is selected from: (i) hydrogen; (ii) a substituted or unsubstituted, linear or branched alkyl group, wherein said group is optionally substituted with a substituent selected from amino, hydroxyl, aminoalkoxyl, guanindinyl, and carbonyl substituted with hydroxy; provided that when R 8 is alkyl, said alkyl is optionally substituted with one or more substituents selected from hydroxyl, amino, carboxyl, piperidinyl, and pyrolidinyl; (iii) unsubstituted hydroxycarbonylethyl or hydroxycarbonylethyl substituted with hydroxyl; (iv) —(CH 2 ) n NH 2 , wherein n is 1, 2, 3, or 4; and (v) —(CH 2 ) n C(═O)R 17 , wherein n is 1, 2, 3, or 4; and R 17 is selected from NH 2 , R 9 is selected from hydrogen, cyclopropyl, trifluoromethyl, unsubstituted C1-C2 alkyl, and methyl substituted with cyclopropyl, hydroxyl, and amino; R 10 , R 11 , R 12 , R 15 and R 16 are independently selected from hydrogen, alkoxy, halogen, and alkyl; R 13 and R 14 are independently selected from hydrogen, alkoxy, halogen, and alkyl, or R 13 and R 14 are joined together to form an alkylene group; R 25 is selected from hydrogen, alkyl, hydroxyalkyl, and aralkyl; and R 26 is selected from haloalkyl, hydroxyl, tetrahydronaphthyl, —CH(CH 3 )C(═O)NH(naphthyl)quinolinylmethyl, benzothiophenylmethyl, —CH 2 CH 2 NHC(═O)(aryl), and —C(H)(aryl)(R 29 ), wherein aryl is optionally substituted with one or more halogen groups, and wherein the aryl group in —C(H)(aryl)(R 29 ) is a naphthyl or benzothiophenyl group; and R 29 is hydrogen.