Patent ID: 8034954

Claim:
A compound having the formula wherein X 1 is —S; R 1 is substituted or unsubstituted cycloalkyl, substituted aryl, or substituted heteroaryl, wherein the substituted aryl or substituted heteroaryl is exclusively substituted with one to three substituents selected from the group consisting of unsubstituted —OR′ and halogen groups, wherein R′ is hydrogen or alkyl; R 2 has the formula: wherein X 2 and X 3 are independently ═N— or ═C(R 6 )—, wherein X 3 is ═C(R 6 )— when X 2 is ═N; X 4 is ═C(R 6 )—; R 5 and R 6 are independently hydrogen, halogen, —CF 3 , -L 3 -R 7 , -L 3 -OR 7 , -L 3 -NR 8 R 9 , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; L 3 is a bond or substituted or unsubstituted alkylene; and R 7 , R 8 , and R 9 are independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl, wherein an R 8 and an R 9 are optionally joined with the nitrogen to which they are attached to form a substituted or unsubstituted heterocycloalkyl, or substituted or unsubstituted heteroaryl, wherein two R 7 substituents are optionally joined with the oxygen to which they are attached to form a substituted or unsubstituted heterocycloalkyl, and wherein an R 8 and an R 7 are optionally joined with the nitrogen and oxygen to which they are attached, respectively, to form a substituted or unsubstituted heterocycloalkyl, or substituted or unsubstituted heteroaryl; L 1 is —S(O) 2 — and L 2 is —N(R 4 )—; wherein R 4 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; or a pharmaceutically acceptable salt of the compound, wherein the compound is an antagonist of a calcium channel.