Patent ID: 7354953

Claim:
A method for time release delivery of chromium complex 2 [Cr 3 O(carboxylate) 6 (H 2 O) 3 ] + (2) comprising: administering to a subject in need thereof a time release composition, comprising: a chromium complex having formula 3 [Cr 3 O(carboxylate) 6 (ligand) 3 ] + (3) wherein carboxylate is a C2-C5 alkyl carboxylate and wherein the ligand is a ligand that (i) renders the chromium complex insoluble or only slightly soluble in water and (ii) is acid labile, being readily displaced under acidic conditions below pH=4 and replaced by water to make the resulting water soluble complex 2 [Cr 3 O(carboxylate) 6 (H 2 O) 3 ] + (2).