Patent ID: 7378415

Claim:
A compound of the formula I: or a pharmaceutically acceptable salt or solvate thereof, wherein: Ar is optionally substituted phenyl or optionally substituted naphthyl; X is —CH 2 — or C═O; Y is O; k is 1; m is from 0 to 3; each R 1 is independently halo, alkyl, haloalkyl, heteroalkyl, alkoxy, cyano, —S(O) q —R b , —C(═O)—NR c R d , —SO 2 —NR c R d , N(R e )—C(═O)—R f , or —C(═O)—R f , where q is from 0 to 2, R b , R c , R d and R e each independently is hydrogen or alkyl, and R f is hydrogen, alkyl, alkoxy or hydroxy; R 2 and R 3 each independently is hydrogen or alkyl, or R 2 and R 3 together with the carbon atom to which they are attached may form a carbocyclic ring of four to six members; R 4 is: and R 7 and R 8 each independently is hydrogen or alkyl.