Patent ID: RE41286

Claim:
A product for repair of cartilage lesions, comprising: a. a cartilage repair matrix suitable for conforming to a defect in cartilage; and b. a cartilage-inducing composition contained on or within said matrix comprising a mixture of proteins comprising: transforming growth factor β1 (TGFβ1), bone morphogenetic protein (BMP)-2, BMP-3, and BMP-7; wherein the quantity of said TGFβ1 in said mixture is greater than 1% of total proteins in said mixture; wherein the quantity of said BMP-2 in said mixture is from about 0.01% to about 10% of total proteins in said mixture; wherein the quantity of said BMP-3 in said mixture is from about 0.1% to about 15% of total proteins in said mixture; and, wherein the quantity of said BMP-7 in said mixture is from about 0.01% to about 10% of total proteins in said mixture.