Patent ID: 7351380

Claim:
A microfluidic device comprising: a first substrate comprising a resin and having upper and lower surfaces; a plurality of flow connectors embedded in the first substrate, the plurality of flow connectors comprising first and second ends, the second end projecting from the upper surface of the substrate and the first end being substantially flush with the lower surface of the substrate; a flow path extending between the first and second ends; a flange extending radially outward proximate the first end; a coupling face positioned between the first end and the flange; and an annular groove circumscribing the coupling face; a second substrate bonded to the first substrate, the second substrate comprising an upper and a lower surface, the upper surface being bonded to the lower surface of the first substrate; one or more fluid channel embedded therein; and a plurality of inlets in fluid communication with at least one of the one or more fluid channels, the inlets located in correspondence with the flow connectors and extending through the upper surface of the second substrate.