Patent ID: 7276481

Claim:
A pharmaceutical composition for bone elongation or treating skeletal dysplasias comprising at least one natriuretic peptide variant set forth in SEQ ID NO:5 wherein Xaa=Leu, Ile, Val; Xbb=Lys, Leu, Met; Xcc=Leu, Ile, Ala, Val; Xdd=Ser, Ala, Gly, Thr, Asn; Xee=Ala, Trp, His, Lys, Ser, Gly; Xff=Gly, Lys, Ala, Leu; and Xgg=Leu, Met, and a carrier or excipient, wherein SEQ ID NO:5 is other than amino acid sequence set forth in SEQ ID NO:2.