Patent ID: 8188261

Claim:
A SIMRA compound having the sequence: (a) 5′-UGC 1 UGC 1 C 1 UUUG-m-GUUUC 1 C 1 GUC 1 GU-5′(5′-SEQ ID NO: 43-3′-m-3′-SEQ ID NO: 43-5′); or (b) 5′-UG 1 CUG 1 CCUUUG 1 -Y-X-Y-G 1 UUUCCG 1 UCG 1 U-5′(5′-SEQ ID NO: 178-3′-Y-X-Y-3′-SEQ ID NO: 178-5′); wherein G 1 is 7-deaza-rG, C 1 is ara-C, m is cis,trans-cyclohexanetriol, X is a glycerol linker, and Y is 1,3-propanediol.