Patent ID: 8652776

Claim:
A method of treating a human patient for one or more symptoms of a psychotic disorder, the method comprising: determining, from a biological sample of the patient, the patient's genotype in both copies of the single nucleotide polymorphism (SNP) locus rs3924426; and treating the patient based upon whether the patient's genotype at the rs3924426 SNP locus is associated with increased QT prolongation, wherein treating includes: in the case that the patient has a TT genotype at the rs3924426 SNP locus, administering to the patient an effective amount of iloperidone or a pharmaceutically-acceptable salt thereof, the effective amount being less than would be administered to a patient who does not have a TT genotype at the rs3924426 SNP locus; or in the case that the patient does not have a TT genotype at the rs3924426 SNP locus, administering to the patient an increased amount of iloperidone, the increased amount being more than would be administered to a patient who has a TT genotype at the rs3924426 SNP locus.