Patent ID: 8758808

Claim:
A method of making an adhesive reservoir for transdermal drug delivery, comprising: providing an acrylate polymer capable of dissolving a drug and permeation enhancer in a combined dissolved amount in the acrylate polymer of at least 30 wt %, the acrylate polymer having a T g of greater than −10° C. without the at least one permeation enhancer and without the at least one drug, the acrylate polymer comprising a soft monomer component of no more than 40 wt %, 40 wt % or more of a hard monomer component, at least a portion of the hard monomer component being hard polar functional monomer, and 10 to 35 wt % of a polar functional monomer component, at least a portion of the polar functional monomer component being hard polar functional monomer, incorporating the drug and permeation enhancer in the acrylate polymer in an amount of at least 30 wt % to result in a single phase reservoir so that dissolved drug and permeation enhancer constitute together more than 30 wt % and the acrylate polymer constitutes 45 wt % to 80 wt % in solids of the reservoir, wherein the reservoir is applicable as a pressure sensitive adhesive to a body surface.