Patent ID: 7652150

Claim:
A compound of the general formula I: wherein the sulphur atom is attached to the indole via any ring carbon of the indole and wherein R 1 -R 2 are independently selected from hydrogen, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl or R 1 and R 2 together with the nitrogen form a 4-7 membered ring containing zero or one double bond, optionally said ring in addition to said nitrogen comprises one further heteroatom selected from nitrogen, oxygen and sulphur; R 3 -R 7 and R 9 -R 12 are independently selected from hydrogen, halogen, cyano, nitro, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl, amino, C 1-6 -alk(en/yn)ylamino, di-(C 1-6 -alk(en/yn)yl)amino, C 1-6 -alk(en/yn)ylcarbonyl, aminocarbonyl, C 1-6 -alk(en/yn)ylaminocarbonyl, di-(C 1-6 -alk(en/yn)yl)aminocarbonyl, hydroxy, C 1-6 -alk(en/yn)yloxy, C 1-6 -alk(en/yn)ylthio, halo-C 1-6 -alk(en/yn)yl, halo-C 1-6 -alk(en/yn)ylsulfonyl, halo-C 1-6 -alk(en/yn)ylsulfanyl and C 1-6 -alk(en/yn)ylsulfonyl; R 8 is halogen; and R 13 is selected from hydrogen or C 1-6 -alk(en/yn)yl; or a pharmaceutically acceptable salt thereof; with the provisos that: when the sulphur atom is attached via atom nr. 2 of the indole then R 7 does not exist; when the sulphur atom is attached via atom nr. 3 of the indole then R 12 does not exist; when the sulphur atom is attached via atom nr. 4 of the indole then R 8 does not exist; when the sulphur atom is attached via atom nr. 5 of the indole then R 9 does not exist; when the sulphur atom is attached via atom nr. 6 of the indole then R 10 does not exist; and when the sulphur atom is attached via atom nr. 7 of the indole then R 11 does not exist.