Patent ID: 7183447

Claim:
A process for the preparation of a ring compound of formulae I to IV where m and n, independently of one another, are identical or different and are 0 or 1, but the sum (m+n) is 1 or 2, X is a single bond, L, independently of one another, are identical or different and are R, F, Cl, Br, I, OH, OR, SH, SR, CN, NO 2 , NO, CHO, COOH, COOR, CONH 2 , CONHR, CONR 2 , CF 3 , NH 2 , NHR or NR 2 , R is an alkyl, alkenyl or acyl group having from up to 12 carbon atoms, or an aryl group having 6 carbon atoms, which is optionally substituted by an alkyl group having from 1 to 12 carbon atoms, and, a, b, c, d, e and f, independently of one another, are identical or different and are 0, 1 or 2, and the sum (a+b+c+d+e+f)=1 to 8, one or two CH groups in the aromatic ring systems of the formulae I to IV may be replaced by N, R 1 and R 2 , independently of one another, are identical or different and are H, F, Cl, CN, NCS, a straight-chain or branched, optionally chiral alkyl radical or alkoxy radical having from 1 to 12 carbon atoms or an alkenyl radical or alkynyl radical having from 2 to 8 carbon atoms, in each of which, in addition, one CH 2 group may be replaced by —O—, —CO—, —O—CO— or —COO— in such a way that heteroatoms are not linked directly to one another and/or one or more H may be replaced by halogen, and in the case where m=0 in R 1 or n=0 in R 2 , one CH 2 group in R 1 or R 2 may be replaced by one of the following groups: a) trans-1,4-cyclohexylene, in which, in addition, one or more non-adjacent CH 2 groups may be replaced by —O— and/or —S—, b) a radical from the group consisting of 1,4-bicyclo[2.2.2]octylene, piperidine-1,4-diyl, naphthalene-2,6-diyl, decahydronaphthalene-2,6-diyl and 1,2,3,4-tetrahydronaphthalene-2,6-diyl, or c) 1,4-cyclohexenylene, and in which the radicals a), b) and c) may also be substituted by CN and/or halogen, said process comprising: preparing a ring compound of formulae I to IV, via combinatorial synthesis, starting from a compound of formulae V to VIII where Z is I, Cl, Br or triflate, M is Si, Ge or Sn, and R 3 , R 4 and R 5 , independently of one another, are identical or different and are H, C 1 –C 12 -alkyl or C 1 –C 12 -alkoxy, in which the following reaction steps are carried out in a matrix-like arrangement of reaction vessels: A) Suzuki coupling with a boronic acid or a boronic acid ester of formula X where R 6 and R 7 , independently of one another, are identical or different and are H, C 1 –C 12 -alkyl, C 2 –C 12 -alkenyl or aryl, and where R 6 and R 7 may also be bridged in a cyclic manner, B) subsequent halo-demetallation, and C) Suzuki coupling with a boronic acid or a boronic acid ester of where one or two CH groups in the aromatic ring systems of formulae V to VIII and X and XI may also be replaced by N.