Patent ID: 6921764

Claim:
A compound of the formula wherein A is a thieno fused aromatic ring; B is phenyl, pyridyl or pyrimidyl; X is N or CH; Y and Z represents —CH 2 NH— or —NHCH 2 —; R 1 is selected from hydrogen, (C 1 -C 6 )alkyl optionally substituted with from one to three fluorine atoms, cyano, halo, amino, nitro and (C 1 -C 6 )alkoxy optionally substituted with from one to three fluorine atoms; R 2 is halo, cyano, (C 1 -C 6 )alkyl optionally substituted with from one to three fluorine atoms, nitro, amino, (C 1 -C 6 )alkylthio, (C 1 -C 6 )alkoxy optionally substituted with from one to three fluorine atoms, hydroxyl, H—C(═O)—, (C 1 -C 6 )alkyl—O—-C(═O)— or NH 2 —C(═O)—; R 3 and R 4 are selected, independently, from hydrogen, (C 1 -C 6 )alkyl optionally substituted with from one to three fluorine atoms, halo, cyano, hydroxy (C 1 -C 6 )alkoxy optionally substituted with from one to three fluorine atoms, —C(═O)H, —CH 2 —OR 5 and —CH 2 NR 6 R 7; R 5 is hydrogen, (C 1 -C 6 )alkyl or —C(═O)(C 1 -C 6 )alkyl; and R 6 and R 7 are selected, independently, from hydrogen, (C 1 -C 6 )alkyl and —C(═O)(C 1 -C 6 )alkyl; or R 6 and R 7 , taken together with the nitrogen to which they are attached, form a four to seven membered saturated or unsaturated ring wherein one of the carbon atoms of such ring may optionally be replaced by oxygen or nitrogen; or a pharmaceutically acceptable salt of such compound.