Patent ID: 8518875

Claim:
A compound of formula I wherein; R3 is H, F, Cl, Br, CF 3 , OCF 3 , COOH, COO—(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, (C 3 -C 8 )-Cycloalkyl, phenyl, or O-phenyl, wherein the alkyl and phenyl are optionally substituted one or more times by R12; R1 and R5 are, independently, H, F, Cl, Br, CF 3 , COOH, COO—(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, phenyl, or O-phenyl, wherein the alkyl and phenyl are optionally substituted one or more times by R12; R2 and R4 are, independently, H, F, Cl, Br, CF 3 , COOH, COO—(C 1 -C 6 )-alkyl, or (C 1 -C 6 )-alkyl; R6 is OH, F, Cl, Br, CN, OCH 3 , OCF 3 , CH 3 , CF 3 , (C 1 -C 6 )-alkyl or O—(C 1 -C 6 )-alkyl, wherein the alkyl is optionally substituted one or more times by OH, F, Cl, Br or CN; R7 and R8 are H; X is a C 2 alkylene substituted by one C 3 alkynyl group; m is 0, 1, 2, 3 or 4; and R9 and R10 are, independently, H, (C 1 -C 6 )-alkyl or phenyl, wherein the alkyl is optionally substituted one or more times by F, Cl or Br, and the phenyl is optionally substituted one or more times by R6; R12 is F, Cl, Br, CN, OH, O—(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, NR9R10, COOH, or COO—(C 1 -C 4 )-alkyl; or a pharmaceutically acceptable salt thereof.