Patent ID: 7572817

Claim:
A compound of formula (I): wherein: R 1 is naphthyl, pyridinyl, 1,2,3,4-tetrahydropyrimidin-2,4-dione-yl, tetrahydrothienyl or phenyl, wherein said phenyl is substituted by 0, 1, 2 or 3 substituents selected from halogen, hydroxy, cyano, C 1-4 alkyl, C 1-4 alkoxy, CF 3 , OCF 3 , methylenedioxy, C(O)R 3 , S(O) 2 R 4 , phenyl, phenoxy and tetrahydrofuranyloxy; R 2 is aminopyridinyl, aminothiazolyl or 3-azabicyclo[3.2.1]octyl; R 3 is hydroxy, C 1-4 alkoxy, NR 5 R 6 or an N-linked 5- or 6-membered heterocyclic ring, wherein said N-linked 5- or 6-membered heterocyclic ring is substituted by 0, 1 or 2 substituents selected from hydroxy, oxo, C 1-4 alkyl, CO 2 (C 1-4 alkyl) and phenyl; R 4 is NR 7 R 8 or an N-linked 5- or 6-membered heterocyclic ring, wherein said N-linked 5- or 6-membered heterocyclic ring is substituted by 0 or 1 substituent selected from hydroxy, oxo, C 1-4 alkyl, CO 2 (C 1-4 alkyl) and phenyl; or fused to a benzene ring which is optionally substituted by 0, 1 or 2 substituents independently selected from C 1-4 alkoxy; R 5 , R 6 , R 7 and R 8 are, independently, hydrogen, C 2-4 alkenyl or C 1-4 alkyl, wherein said C 1-4 alkyl is substituted by 0, 1 or 2 substituents selected from halogen, cyano, hydroxy, phenyl, pyridinyl, CO 2 H or CO 2 (C 1-4 alkyl); provided that when R 2 is 6-aminopyridin-3-yl then R 1 is naphthyl, pyridinyl, 1,2,3,4-tetrahydropyrimidin-2,4-dione-yl, tetrahydrothienyl or phenyl, wherein said phenyl is substituted by 1, 2, or 3 substituents selected from halogen, hydroxy, cyano, C 1-4 alkyl, C 1-4 alkoxy, CF 3 , OCF 3 , methylenedioxy, C(O)R 3 , S(O) 2 R 4 , phenyl, phenoxy and tetrahydrofuranoxy; or a pharmaceutically acceptable salt thereof.