Patent ID: 7123953

Claim:
A method of screening for risk of cardiac arrhythmia in a subject, the method comprising the steps of: (a) collecting at least one QT interval data set and at least one RR interval data set from the subject during (i) a stage of gradually increasing heart rate, (ii) a stage of gradually decreasing heart rate, or (iii) both a stage of gradually increasing heart rate and gradually decreasing heart rate; (b) separating fluctuations from slow trends in said at least one QT interval data set and in said at least one RR interval data set to provide QT fluctuations and RR fluctuations; (c) comparing said QT fluctuations and said RR fluctuations to one another to determine the difference therebetween; and (d) generating from the comparison of step (c) a measure of risk of cardiac arrhythmia in said subject, wherein a greater difference between QT fluctuations and RR fluctuations indicates greater risk of cardiac arrhythmia in said subject.