Patent ID: 7235626

Claim:
An isolated structurally-constrained cyclic peptide, said cyclic peptide consisting of an amino acid sequence of C1-A1-A2-(A3) n -A4-A5-C2 (SEQ ID NO: 1), wherein C1 and C2 are cysteines; A1, A2, A3, A4, and A5 are naturally occurring L-amino acids; A1 and A5 are independently amino acids W, Y, F, H, I, V, or T; A2 is amino acid W; A3 is any naturally occurring L-amino acid and n is an integer that is 4; A4 is amino acids W or L; and C1 and C2 together form a disulfide bond thereby forming a cyclic peptide; the amino terminus of C1 is optionally protected with an amino protecting group; and the carboxy terminus of C2 is optionally protected with a carboxy protecting group; and wherein the cyclic peptide stabilizes a β-turn, β-hairpin, β-bulge, or γ-turn sequence.