Patent ID: 7807672

Claim:
A compound of formula 1.0: or the pharmaceutically acceptable salts thereof, wherein: Y 1 , Y 2 , and Y 3 are each independently selected from the group consisting of: —CH═and —CR 9 ═; z is 1; Q is a substituent selected from the group consisting of: Q 1 is phenyl; Z 1 is —CH 2 —; R 1 is selected from the group consisting of: methyl, i-propyl, t-butyl, cyclopropyl, o-F-phenyl, m-F-phenyl, p-F-phenyl, Cl, Br, F, phenyl, —CF 3 , —C(O)NH 2 , —CH 2 OH, H, pyridyl, and pyrazolyl; R 2 is H, ethyl, ethynyl, propynyl, —CH 2 —CH═CH 2 , —OCH 3 , —CH 2 OCH 3 , —CH 2 OH, —CH 2 F, —CF 3 , —CH 2 NH 2 , —NH 2 , —CH 3 , —CH 2 CN, —CH 2 OC 2 H 5 , —(CH 2 ) 3 OCH 3 , and —CH 2 -triazolyl; each R 3 , R 4 , R 6 and R 7 is independently selected from the group consisting of: H and C 1 to C 6 alkyl; R 5 is selected from the group consisting of: R 8 is H; each R 9 is independently selected from the group consisting of: halogen, and R 10 wherein said R 10 is C 1 to C 6 alkyl; each R 35 is independently selected from the group consisting of: H and C 1 to C 6 alkyl; and R 36 is selected from the group consisting of: H and C 1 to C 6 alkyl.