Patent ID: 7601734

Claim:
A cyclic amine compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof wherein X is O, S, or NR 2 (wherein R 2 is a hydrogen atom, a C 1 -C 12 alkyl group, a C 2 -C 8 alkanoyl group or a C 2 -C 13 alkoxycarbonyl group); R 1 is, when X is O or S, a hydrogen atom, a cyano group, a carboxyl group, a C 2 -C 13 alkoxycarbonyl group, a carbamoyl group, a C 2 -C 13 alkylaminocarbonyl group, a C 3 -C 25 dialkylaminocarbonyl group, a C 3 -C 13 cyclic aminocarbonyl group, a C 1 -C 12 alkyl group, a C 1 -C 12 alkoxy group, a C 1 -C 8 alkylthio group, a C 1 -C 8 alkylsulfinyl group, a C 1 -C 8 alkylsulfonyl group, a C 2 -C 8 alkanoyl group, a nitro group or a hydroxyl group; and when X is NR 2 (wherein R 2 is as defined above), R 1 is a cyano group, a carboxyl group, a C 2 -C 13 alkoxycarbonyl group, a carbamoyl group, a C 2 -C 13 alkylaminocarbonyl group, a C 3 -C 25 dialkylaminocarbonyl group, a C 3 -C 13 cyclic aminocarbonyl group, a C 1 -C 12 alkyl group, a C 1 -C 12 alkoxy group, a alkylthio group, a C 1 -C 8 alkylsulfinyl group, a C 1 -C 8 alkylsulfonyl group, a C 2 -C 8 alkanoyl group, a nitro group or a hydroxyl group; Ar 1 and Ar 2 each represent a phenyl group which may be substituted by 1 to 3 substituents selected arbitrarily from the group consisting of halogen atoms, C 1 -C 12 alkyl, C 1 -C 8 haloalkyl, C 7 -C 26 aralkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 1 -C 12 alkoxy, C 1 -C 8 haloalkoxy, hydroxyl, C 1 -C 8 alkylthio, C 1 -C 8 alkylsulfinyl, C 1 -C 8 alkylsulfonyl, C 1 -C 12 alkylamino, C 2 -C 24 dialkylamino, C 2 -C 12 cyclic amino, amino, C 2 -C 13 alkoxycarbonyl, carboxyl, C 2 -C 13 alkylaminocarbonyl, C 3 -C 25 dialkylaminocarbonyl, C 3 -C 13 cyclic aminocarbonyl, carbamoyl, C 2 -C 8 alkanoyl, cyano, nitro, phenyl and phenoxy groups; ring B is a benzene ring which may be substituted by 1 to 3 substituents selected arbitrarily from the group consisting of halogen atoms, C 1 -C 12 alkyl, C 1 -C 8 haloalkyl, C 7 -C 26 aralkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 1 -C 12 alkoxy, C 1 -C 8 haloalkoxy, hydroxyl, C 1 -C 8 alkylthio, C 1 -C 8 alkylsulfinyl, C 1 -C 8 alkylsulfonyl, C 1 -C 12 alkylamino, C 2 -C 24 dialkylamino, C 2 -C 12 cyclic amino, amino, C 2 -C 13 alkoxycarbonyl, carboxyl, C 2 -C 13 alkylaminocarbonyl, C 3 -C 25 dialkylaminocarbonyl, C 3 -C 13 cyclic aminocarbonyl, carbamoyl, C 2 -C 8 alkanoyl, cyano, nitro, phenyl and phenoxy groups; n is an integer from 1 to 10; and p represents 2 and q represents 1.