Patent ID: 8207223

Claim:
A pharmaceutical composition comprising a compound selected from the group of formula (I-2) wherein R 1-2 is (2) —COO—Y 2 —R 9-2 , (3) —COO—Z 1-2 —Z 2-2 —Z 3-2 , wherein Y 2 is bond or C1-10 alkylene, R 9-2 is (1) phenyl or (2) biphenyl optionally substituted by 1-3 C1-10 alkyl, C 1-10 alkoxy or halogen atom, Z 1-2 is (1) C1-15 alkylene, Z 2-2 is (1) —CO—, (2) —OCO—, (3) —COO—, (4) —CONR 11-2 —, (6) —O—, (13) —OCONR 17-2 — or (14) —OCOO—, Z 3-2 is (1) hydrogen atom, (2) C1-15 alkyl, (3) C2-15 alkenyl, (5) ring1 2 or ring1 2 is (1) C3-15 mono-, bi- or tri-carbocyclic aryl which may be partially or fully saturated R 11-2 and R 17-2 are each independently, hydrogen atom or C1-15 alkyl, m-2 is 1 or 2, R 2-1 is oxo, R 3-1 is hydrogen atom or hydroxy, R 4a-1 and R 4b-1 are each independently, hydrogen atom or C1-4 alkyl, R 5-1 is phenyl substituted by C1-4 alkyloxy-C1-4 alkyl, is single bond or double bond, wherein when R 2-1 is O—COR 8-1 , C8-9 position is double bond, or a non-toxic salt thereof, or cyclodextrin clathrate thereof, as an active ingredient.