Patent ID: 7323478

Claim:
A packaged pharmaceutical composition comprising: (a) a pharmaceutical composition comprising: (i) a compound of the formula: or a pharmaceutically acceptable salt thereof wherein: Q represents a group of the Formula: wherein A is C 1 -C 5 alkylene optionally mono-, di, or trisubstituted with substituents independently chosen from C 1 -C 3 alkyl, C 1 -C 3 alkoxy, halogen, halo(C 1 -C 3 )alkyl, halo(C 1 -C 3 )alkoxy, hydroxy, amino, and mono- or di(C 1 -C 3 ) alkylamino; R 1 , R 2 , R 3 , R 4 , R 5 , 6 , R 7 , and R 8 are the same or different and independently represent hydrogen, halogen, cyano, nitro, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, hydroxy, amino, mono or di(C 1 -C 6 ) alkyl amino, halo(C 1 -C 6 )alkyl, halo(C 1 -C 6 )alkoxy, C 1 -C 6 alkanoyl, C 1 -C 6 alkoxycarbonyl, —COOH, —SO 2 NH 2 , mono or dialkylsulfonamido, —C(O)NH 2 , or mono or di(C 1 -C 6 )alkylcarboxamido; R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , and R 19 independently represent hydrogen or 1 -C 6 alkyl; W is nitrogen or C—R a where R a represents hydrogen, hydroxy, C 1 -C 6 alkoxy, C 1 -C 6 alkyl or cyano; X represents halogen, cyano, nitro, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, hydroxy, amino, mono or di(C 1 -C 6 )alkylamino, halo(C 1 -C 6 )alkyl, halo(C 1 -C 6 )alkoxy, C 1 -C 6 alkanoyl, C 1 -C 6 alkoxycarbonyl, —COOH, —CONH 2 , mono- or di(C 1 -C 6 )alkylcarboxamido, —SO 2 NH 2 , mono or di(C 1 -C 6 )alkylsulfonamido; or X represents phenyl which may be optionally substituted by up to five substituents, which may be the same or different and are selected from the group consisting of hydrogen, halogen, cyano, nitro, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, hydroxy, amino, mono or di(C 1 -C 6 )alkyl amino, halo(C 1 -C 6 )alkyl, halo(C 1 -C 6 )alkoxy, C 1 -C 6 alkanoyl, C 1 -C 6 alkoxycarbonyl, —COOH, —CONH 2 , mono- or di-(C 1 -C 6 ) alkylcarboxamido, —SO 2 NH 2 and mono or di(C 1 -C 6 )alkylsulfonamido; Y is oxygen, sulfur, —S(O)—, or —SO 2 -; and Z is C 1 -C 6 alkyl or mono, di or trifluoromethyl; and (ii) at least one pharmaceutically acceptable carrier or excipient; and (b) instructions for using the composition to treat a patient suffering from obesity.