Patent ID: 8865748

Claim:
A composition for stabilizing hypoxia inducible factor-2 alpha (HIF-2α) comprising: A) an effective amount of a compound having the formula: wherein R is chosen from: i) —OR 1 ; ii) —NR 2 R 3 ; or iii) —OM 1 ; R 1 is: i) hydrogen; or ii) C 1 -C 6 linear, C 3 -C 6 branched or C 3 -C 6 cyclic alkyl; R 2 and R 3 are independently: i) hydrogen; ii) C 1 -C 6 linear, C 3 -C 6 branched or C 3 -C 6 cyclic alkyl; or iii) R 2 and R 3 can be taken together to form a ring having from 2 to 7 carbon atoms and from 1 to 3 heteroatoms chosen from nitrogen, oxygen and sulfur including the nitrogen atom to which R 2 and R 3 are bonded; and M 1 is a cation; and R 4 is: i) —OH; or ii) —OM 2 ; and M 2 is a cation; and B) one or more pharmaceutically acceptable ingredients; and C) Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF).