Patent ID: 7378397

Claim:
A compound of formula I: wherein: R 1 is an optionally substituted 4-, 5- or 6-membered heterocyclic ring having one or more heteroatoms, in which at least one carbon atom of the ring is substituted with O, N, or S; X 1 is —CO— or —CS— or —CH 2 CO— or CH(R 4 ) wherein R 4 is H or optionally substituted alkyl or —COOH or —COOR 11 wherein R 11 is optionally substituted alkyl; X 2 and X 3 are independently —CO— or —CS—; Z is —CH 2 — or —S— or —O— or —NH—; Q is O or S; R 2 is H or optionally substituted alkyl or an optionally substituted carbocyclic ring; R 3 is H or optionally substituted alkyl or an optionally substituted mono- or polycyclic ring, optionally having one or more heteroatoms in the ring(s) and optionally being a fused ring; or R 2 and R 3 together form an optionally substituted mono- or polycyclic ring optionally having one or more heteroatoms in the ring(s) and optionally being a fused ring; R 5 and R 6 are independently H, or lower alkyl; R 7 and R 8 are independently H, or optionally substituted lower alkyl; R 9 and R 10 are independently H, or optionally substituted alkyl, or an optionally substituted carbocyclic ring; Y is —(CH 2 ) n — where n is 0, 1, 2 or 3 provided that when R 2 and R 3 form part of the ring n is 0; provided that when R 1 is: and X 1 , X 2 and X 3 are —CO— and R 5 , R 6 , R 7 , R 8 , R 9 , R 10 are H and Z is —CH 2 — and Q is O and Y is —(CH 2 ) n — where n is 0, then R 2 and R 3 are not both H; and pharmaceutically acceptable salts thereof.