Patent ID: 8623381

Claim:
A recombinant vaccinia virus, wherein said recombinant vaccinia virus comprises a genomic sequence SEQ ID NO: 1 with at least one deletion, and wherein said at least one deletion is selected from the group consisting of: deletion of nucleotides 19758 to 28309 (Δ18) and deletion of nucleotides 161293 to 164811 (Δ20); deletion of nucleotides 19758 to 28309 (Δ18) and deletion of nucleotides 181231 to 183304 (Δ21); deletion of nucleotides 19758 to 28309 (Δ18) and deletion of nucleotides 6118 to 9677 (Δ22); deletion of nucleotides 19758 to 28309 (Δ18) and a deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 161293 to 164811 (Δ20) and deletion of nucleotides 181231 to 183304 (Δ21); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 161293 to 164811 (Δ20) and deletion of nucleotides 6118 to 9677 (Δ22); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 161293 to 164811 (Δ20) and deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 181231 to 183304 (Δ21) and deletion of nucleotides 6118 to 9677 (Δ22); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 181231 to 183304 (Δ21) and deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 6118 to 9677 (Δ22) and deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 161293 to 164811 (Δ20), deletion of nucleotides 181231 to 183304 (Δ21) and deletion of nucleotides 6118 to 9677 (Δ22); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 161293 to 164811 (Δ20), deletion of nucleotides 181231 to 183304 (Δ21) and deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23); deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 181231 to 183304 (Δ21), deletion of nucleotides 6118 to 9677 (Δ22) and deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23); and deletion of nucleotides 19758 to 28309 (Δ18), deletion of nucleotides 161293 to 164811 (Δ20), deletion of nucleotides 181231 to 183304 (Δ21), deletion of nucleotides 6118 to 9677 (Δ22) and deletion of nucleotides 1833 to 3574 and 185848 to 187589 (Δ23).