Patent ID: 7371729

Claim:
A parenteral pharmaceutical formulation comprising a pharmaceutically acceptable base addition salt of a boronic acid of formula (VIII): X-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH) 2 (VIII), wherein X is R 6 —(CH 2 ) p —C(O)—, R 6 —(CH 2 ) p —S(O) 2 —, R 6 —(CH 2 ) p —NH—C(O)— or R 6 —(CH 2 ) p —O—C(O)—, wherein p is 0, 1, 2, 3, 4, 5 or 6 and R 6 is H or a 5 to 13-membered cyclic group which is unsubstituted or substituted by 1, 2 or 3 substituents selected from halogen; amino; nitro; hydroxy; a C 5 -C 6 cyclic group; C 1 -C 4 alkyl and C 1 -C 4 alkyl containing, or linked to the cyclic group through, an in-chain O atom, the aforesaid alkyl groups optionally being substituted by a substituent selected from halogen, amino, nitro, hydroxy and a C 5 -C 6 cyclic group, wherein the salt in the parenteral pharmaceutical formulation is a salt of the boronic acid with an alkali metal, an aminosugar, a guanidine or an amine of formula (XI): where n is from 1 to 6, R 2 is H, carboxylate or derivatised carboxylate, R 3 is H, C 1 -C 4 alkyl or a residue of a natural or unnatural amino acid.