Patent ID: 8148363

Claim:
A compound of formula IA or IB or a pharmaceutically acceptable salt, or ester thereof; wherein each R 7 is independently selected from the group consisting of hydrogen, halo, alkyl, aminoalkyl, hydroxyalkyl, haloalkyl, alkoxy, -alkyl-O-hydroxyalkyl, haloalkoxy, cyano, hydroxy, —C(O)NR 5 R 6 , —C(═NOR 5 )N(R 6 ) 2 , ——C(O)OR 4 , -alkyl-NR 5 C(═O)OR 4 , -alkyl-S(═O ) 2 -aryl, -alkyl-NR 5 S(═O ) 2 -alkyl, —alkyl-NR 5 C(═0)NR 5 -alkyl, -alkyl-heteraryl, -alkyl-heterocyclyl, -alkyl-NR 5 C(═O )alkyl, -alkyl -NR 5 C(═O )aryl, alkoxyalkyl, aryl, heteroaryl, cycloalkyl, heterocycylyl, —NR 5 R 6 , —SR 4 , and —C(O )NR 5 R 6 , each R independently is H, alkyl, haloalkyl, cycloalkyl, heterocyclyl, aryl, heteroaryl, or -(CR 5 R 6 ) n W, wherein W is selected from the group consisting of cycloalkyl, heterocyclyl,aryl, heteroaryl, —C(═O)NR 5 R 6 , C(═O)OR 4 , —OR 4 , —NR 5 R 6 ; each R 4 independently is selected from the group consisting of H, alkyl, —C(═O)-heterocyclyl, —C(═O)NHalkyl, and —C(═O )N(alkyl) 2 ; each R 5 and R 6 is independently selected from the group consisting of H alkyl, —C(═O)alkyl, and —C(═O)Oalkyl.