Patent ID: 7011844

Claim:
A device for the transdermal administration of fluoxetine at a therapeutically effective rate, comprising: (a) a first reservoir comprising an amount of a pharmaceutically acceptable salt of fluoxetinc; (b) a second reservoir comprising an excess of fluoxetine salt at or below saturation when in equilibrium with the first reservoir; (c) a rate-controlling membrane between the first reservoir and the second reservoir; (d) a backing behind the body contacting-distal surface of the second reservoir; and (e) means for maintaining the first and second reservoirs in fluoxetine-transmitting relation with a body surface or membrane, said device having a surface area defining an area of fluoxetine delivery of less than about 60 cm 2 , wherein a therapeutically effective amount of fluoxetine is delivered at a therapeutically effective rate within 250-3200 μg/hr during an administration period of at least 12 hours in order to provide therapeutic blood or plasma levels.