Patent ID: 8193209

Claim:
A method of treating pain in humans consisting of orally administering to a human patient an oral dosage form consisting essentially of (a) two analgesic compounds and/or pharmaceutically acceptable salts thereof consisting of (i) a COX-2 inhibitor selected from meloxicam and/or at least one pharmaceutically acceptable salt thereof and (ii) oxycodone and/or at least one pharmaceutically acceptable salt thereof; and (b) a sustained release carrier, wherein the amount of the COX-2 inhibitor administered is lower than the amount of the COX-2 inhibitor that would normally be required to produce analgesia when the COX-2 inhibitor is used alone; the oxycodone is in an amount from 2.5 mg to 800 mg; and the sustained release carrier is in an amount which causes a sustained release of the meloxicam and the oxycodone when the dosage form contacts gastrointestinal fluid and provides a therapeutic effect for about 12 hours or longer.