Patent ID: 8366934

Claim:
A method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step, said method comprising the following steps of: passing said aqueous [18F] fluoride solution through a solid phase extraction column containing an anion-exchange phase so that said [18F] fluorides are trapped thereon; eluting said [18F] fluorides with an eluting solution so that to release said [18F] fluorides from said anion-exchange phase under the form of a solution which is reactive and immediately usable for a labeling reaction; wherein the eluting solution is an organic solution having a water content lower than 3% and containing at least: a first compound which is a tertiary alcohol-function bearing molecule, a second compound which is a phase transfer agent suitable for radiolabeling and which is necessary to the anion-exchange process.