Patent ID: 8592463

Claim:
Compounds of formula (Ia) wherein X can be either N or CH: when X is N, R 3 is and q is 1, when x is CH, R 3 is R 1 is H; linear, branched or cyclic (C 1 -C 4 ) alkyl, group optionally substituted with one or more halogen, a branched or linear (C 1 -C 4 )alkoxy or a mono- or di-linear branched or cyclic (C 1 -C 6 )alkylamino group; r equals 0, 1, 2 or 3; R 1 ′ represents, independently from one another when r>1, halogen; linear, branched or cyclic (C1-C4) alkoxy group; linear, branched or cyclic (C 1 -C 4 ) alkyl optionally substituted with linear or branched (C 1 -C 4 )alkoxy, alkylamino, or dialkylamino group; R 2 is H, Cl, F or Br; i and j are 1, 2 or 3, the sum i+j cannot exceed 5, and when X is N then i and j cannot be 1 Q is such that no direct bond is formed between two nitrogen atoms or between a nitrogen atom and an oxygen atom and may be carbonyl; aminocarbonyl; carbonylamino, imine; SO 2 ; linear or branched (C 1 -C 6 ) alkyl optionally substituted with one or more fluorines wherein one methylene group may be replaced by O, NRx, carbnonyl or SO 2 or wherein two subsequent methylene groups may be replaced with a carbonylamino, aminocarbonyl, sulphonylamino, aminosulphonyl group; k is 1, 2, 3 or 4; l, m, n, p, p′ and s are independently be 1, 2 or 3; t is 0, 1 or 2; the sums l+m, n+p or p′+s+t cannot exceed 5; T and T′ represent, independently from one another, hydrogen; a linear, branched or cyclic (C 1 -C 6 ) alkyl, azaalkyl, oxaalkyl, alkenyl, azaalkenyl, oxaalkenyl, chain optionally substituted with halogen, amino, cyano, hydroxy, oxo, linear, branched or cyclic (C 1 -C 3 )alkylcarbonyl, alkoxycarbonyl, alkylcarbonylamino, alkylaminocarbonyl, carbamoyl, guanidino, alkenylcarbonyl, oxaalkenylcarbonyl, alkenyloxycarbononyl, alkenylaminocarbonyl; Z is O, S, SO 2 , SO, or NRy′; Ry and Ry′ independently represent H; linear, branched or cyclic (C 1 -C6) alkyl, alkylcarbonyl, alkoxycarbonyl of alkylaminocarbonyl group optionally substituted with one or more fluorine atoms; y and y′ are independently 0, 1, 2 or 3; Y 1 and Y 2 independently represent halogen; hydroxy; amino; cyano; nitro; oxo; linear, or branched (C 1 -C 6 ) alkyl, dihalogen; azaalkyl, oxaalkyl, alkylcarbonyl, oxaalkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl, alkylcarbonylamino, alkenyl, oxaalkenyl, azaalkenyl, alkenylcarbonyl, oxaalkenylcarbonyl, alkenyloxycarbonyl, alkenylaminocarbonyl, alkylamino, mercaptoalkyl, alkoxy, alkylthio group optionally substituted with one or more fluorine atoms; wherein two Y 2 groups may form a 5- to 8-membered ring with spiro or fused junction.