Patent ID: 7947674

Claim:
Compounds of general formula (I) wherein R is the following group of formula (II) wherein X is selected from the group consisting of O, S, CH 2 , COO, CH 2 CO, O(CH 2 ) 2 O, O(CH 2 ) 3 O and N; Z is selected from between N and CH 2 N; Y is selected from aliphatic groups, linear or branched, saturated or unsaturated, having from 1 to 10 carbon atoms, and phenyl, or Y forms with Z a saturated or unsaturated heterocycle, selected from the group consisting of: morpholine, piperidine, pyrimidine, piperazine, pyrrolidine, pyrroline, aniline, julolidine (2,3,6,7-tetrahydro-1H,5H-pirido[3,2,1-Ij]quinoline, and substituted forms thereof; R 4 and R 5 , equal or different from each other, are selected from H and alkyl groups having from 1 to 3 carbon atoms, or they form with the Z group a saturated or unsaturated heterocycle, selected from the group consisting of: morpholine, piperidine, pyrimidine, piperazine, pyrrolidine, pyrroline, aniline, julolidine (2,3,6,7-tetrahydro-1H,5H-pirido[3,2,1-Ij]quinoline), and substituted forms thereof; R 6 is selected from H and aliphatic groups, linear or branched, saturated or unsaturated, having from 1 to 5 carbon atoms, comprising a saturated heterocycle selected from the group consisting of: morpholine, piperidine, piperazine, pyrrolidine, and substituted forms thereof; d, m, and n, equal of different from each other, are selected from 0 and 1; v and s, equal or different from each other, are integers comprised between 1 and 3; R 1 is selected from H and a group of formula (III) wherein G is selected from H and P— (CH 2 ) 1 —(W) f -J, wherein P is selected from the group consisting of O, CH 2 , CO 2 , NHCONH and CONH; l is an integer comprised between 0 and 5; W is selected from the group consisting of O, CO 2 , CONH and NHCONH; f is selected from between 0 and 1; J is H or an alkyl group (CH 2 ) q —CH 3 , wherein q is an integer comprised between 0 and 20; R 2 and R 3 , equal or different from each other, are selected from between R and R 1 , wherein R and R 1 are defined as above, M is chosen from 2H and a metal selected from the group consisting of Zn, Mg, Pt, Pd, Si(OR 7 ) 2 , Ge(OR 7 ) 2 and AlOR 7 , wherein R 7 is chosen from between H and C1-C15 alkyl, and pharmaceutically acceptable salts thereof, with the exception of the following compounds: a) compound of formula (I) wherein M is 2H, R 1 ═R 3 ═H, R═R 2 is a group of formula (II) in which s is 1, X is O, Y is (CH 2 ) 3 , v is 1, Z is N, n=d=l, m is 0, and R 4 ═R 5 ═H; and b) compound of formula (I) wherein M is 2H, R 1 ═R 3 ═H, R═R 2 is a group of formula (II) in which s is 1, X is O, Y is (CH 2 ) 3 , v is 1, Z is N, n=d=1, m is 0, R 4 and R 5 form with Z a phthalimido group.