Patent ID: 8119835

Claim:
A method for preparation of a compound of formula (I) wherein: R 1 is selected from the group consisting of K, Na, Li, H, straight C 1 -C 10 alkyl, branched C 3 -C 10 alkyl or cyclicC 3 -C 10 alkyl and CH 2 OC 1 -C 5 alkyl, from a compound of formula (II) wherein: Hal is selected from the group consisting of Cl, Br and I, by reacting with a compound of formula (III) wherein: R 1 and R 2 independently of each other are selected from the group consisting of K, Na, Li, H, aryl, straight C 1 -C 10 alkyl, branched C 3 -C 10 alkyl and cyclic C 3 -C 10 alkyl, or R 1 and R 2 together form a group —(CR 4 R 5 ) m —, —(CR 6 R 7 ) n —, wherein R 4 , R 5 , R 6 and R 7 independently of each other are selected from the group consisting of aryl, H, straight C 1 -C 5 alkyl, branched C 3 -C 5 alkyl and cyclic C 3 -C 5 alkyl; and m and n independently of each other are 1 or 2, or R 1 and R 2 together form ortho-substituted aryl, R 3 is selected from the group consisting of H and in an inert solvent in presence of a basic agent and a catalyst selected from the group consisting of a palladium catalyst, Pd(0) and Pd(0)-phosphine ligand complex, wherein the product of the reaction between the compound of formula (II) and the compound of formula (III) is not isolated and is further reacted with a compound (IV) wherein: R 9 is selected from the group consisting of K, Na, Li, H, aryl, straight C 1 -C 10 alkyl, branched C 3 -C 10 alkyl, cyclic C 3 -C 10 alkyl, and CH 2 OC 1 -C 5 alkyl; Hal is selected from the group consisting Cl, Br and I, in the same reaction mixture, with or without addition of an inorganic base.