Patent ID: 8901283

Claim:
An isolated antibody that specifically binds NKG2A, the antibody comprising antigen-binding residues from the complementarity-determining regions (CDRs) of murine antibody Z270 and human acceptor framework sequences, wherein said antibody comprises a VL domain that is at least 90% identical to SEQ ID NO: 4 and a VH domain that is at least 90% identical to SEQ ID NO:5, and wherein said antibody comprises CDR-H1 corresponding to residues 31-35 of SEQ ID NO: 5, CDR-H2 corresponding to residues 50-60 of SEQ ID NO: 5, CDR-H3 corresponding to residues 99-114 of SEQ ID NO: 5, CDR-L1 corresponding to residues 24-34 of SEQ ID NO: 4, CDR-L2 corresponding to residues 50-56 of SEQ ID NO: 4 and CDR-L3 corresponding to residues 89-97 of SEQ ID NO: 4.