Patent ID: 8921551

Claim:
A process for preparing a quaternary ammonium salt of formula (4): wherein X is halogen atom, C 1-6 alkylsulfonyloxy group, or C 6-10 arylsulfonyloxy group, and X − is a counteranion thereof, Y is a substituent of the following formula (2a) or (2b): wherein R 1 is independently methylene or oxygen atom; R 2 is independently C 1-6 alkyl group, C 1-6 alkoxy group, or hydroxy group; m and n are independently 0, 1, 2, or 3; and p is 1 or 2, and Z is ═N—R 3 or ═CH—R 4 wherein R 3 is C 1-6 alkyl group, C 3-7 cycloalkyl group, C 5-7 cycloalkenyl group, C 6-10 aryl group, or 5- to 10-membered monocyclic or bicyclic heteroaryl group; R 4 is C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylthio group, C 3-7 cycloalkyl group, C 3-7 cycloalkyloxy group, C 3-7 cycloalkylthio group, C 5-7 cycloalkenyl group, C 5-7 cycloalkenyloxy group, C 5-7 cycloalkenylthio group, C 6-10 aryl group, C 6-10 aryloxy group, C 6-10 arylthio group, 5- to 10-membered monocyclic or bicyclic heteroaryl group, 5- to 10-membered monocyclic or bicyclic heteroaryloxy group, or 5- to 10-membered monocyclic or bicyclic heteroarylthio group, comprising reacting a compound of formula (1): wherein X is independently selected from the above-defined ones, and Y is as defined above, with 1.8 to 15 mole of a compound of formula (3): wherein Z is as defined above, per one mole of the compound of formula (1) to prepare the quaternary ammonium salt of formula (4).