Patent ID: 6852230

Claim:
A method for desalting an aqueous liquid containing a charged substance comprising the steps of: (i) contacting liquid (I) with an ion-exchanger (1) under conditions permitting binding between the ion-exchanger and the substance, said ion exchanger comprising a base matrix carrying an ion-exchange ligand (Ligand 1) that has the opposite charge compared to the substance, (ii) desorbing said substance from said ion-exchanger by the use of a liquid (liquid (II)), wherein (A) ion-exchanger (1) is selected among ion-exchangers that: (a) are capable of binding the substance of interest in an aqueous reference liquid at an ionic strength corresponding to 0.1 M NaCl; and (b) permit a breakthrough capacity at the pH provided by liquid (I) which is more than 2 mg/ml of gel (sedimented), at a breakthrough of 10% and a linear flow velocity of 300 cm/h; and (B) step (ii) comprises that the pH of liquid (II) is adjusted to a pH value that means that the charge difference between the substance and the ligand and/or the ion-exchanger is lowered.