Patent ID: 7514092

Claim:
A method of ameliorating, reducing, or treating progressive degradation of a dermal-epidermal junction and/or degradation of a cell-cell cohesion in skin, comprising topically applying to skin a composition, comprising: (a) a cosmetically, dermatologically, pharmaceutically, or physiologically effective amount at least one plant extract, or any combinations thereof, sufficient to increase expression levels of at least one gene selected from the group consisting of: Beta-catenin, Collagen 4, Collagen 7, Frizzled 10, Estrogen Receptor alpha, Hyaluronic acid synthase, and combinations thereof, wherein said at least one plant extract is Plumbago indica, Sapindus rarak , or Stephania rotunda , either alone or in combination with each other and/or with Cananga odorata ; and (b) a cosmetically, dermatologically, pharmaceutically, or physiologically acceptable vehicle, in an amount effective to ameliorate, reduce, or treat progressive degradation of a dermal-epidermal junction and/or degradation of a cell-cell cohesion in skin.