Patent ID: 8829001

Claim:
A compound of formula 1, or a tautomer, racemate, optical isomer, or pharmaceutically acceptable salt thereof, wherein: L is —CH 2 CH 2 CH 2 CH 2 — or cis- or trans-CH 2 CH═CHCH 2 —; R 1 , R 2 , and R 3 each are independently H, halogen, C 1 -C 6 alkyl, substituted C 1 -C 6 alkyl, C 1 -C 6 alkenyl, substituted C 1 -C 6 alkenyl, C 1 -C 6 alkyloxy, C 1 -C 6 alkylamino, di-(C 1 -C 6 alkyl)amino, C 1-10 hydrocarbonylcarbonyloxy, C 1-10 hydrocarbonylamido, C 1-10 hydrocarbonyloxycarbonyl, carbamoyl, or C 1-10 hydrocarbonylcarbamoyl; wherein the substituent of each group having a substituent is independently selected from halogen, hydroxyl, cyano, nitro, C 1-6 alkyl, C 1-6 alkyloxy, C 1-6 alkylthio, mono-, di- or tri-halogenated C 1-6 alkyl, amino, C 1-6 alkylamino, C 1-10 hydroxycarbonylcarbonyloxy, or C 1-10 hydrocarbonylamido; X is O or S; Y and Z are each independently CH or N; and the carbonyl may be at the 4-, 5-, 6-, or 7-position of the benzoxazolin-2-one or benzthiazolin-2-one ring.