Patent ID: 8628772

Claim:
An isolated monoclonal or polyclonal antibody which binds to an epitope of the HBsAg oligopeptide or polypeptide (i) the epitope comprising an amino acid sequence of at least 5 consecutive amino acids from SEQ ID NO:12, corresponding to amino acids 43-196 of the HBsAg, wherein the at least 5 consecutive amino acids comprise at least one of the amino acids at positions 54, 61, 72, 73, 74, 75, 76, 78, 85, and 87 of SEQ ID NO: 12, and wherein said antibody binds to the epitope; or (ii) the epitope comprising an amino acid sequence of at least 5 consecutive positions from SEQ ID NO:12, corresponding to amino acids 43-196 of the HBsAg, wherein the at least 5 consecutive positions comprise at least one of the positions 54, 61, 72, 73, 74, 75, 76, 78, 85, 87, and 94 of SEQ ID NO: 12, wherein position 54 is alanine, position 61 is isoleucine, position 72 is alanine, position 73 is isoleucine, position 74 is asparagine, position 75 is asparagine, position 76 is arginine, position 78 is glutamine, position 85 is threonine, position 87 is histidine, and position 94 is tyrosine, wherein the remaining positions have the same amino acids as SEQ ID NO:12 at that position, and wherein said antibody binds to the epitope; or (iii) the epitope consisting of 5 consecutive amino acids from SEQ ID NO: 12, wherein the 5 consecutive amino acids comprise at least one of the amino acids at positions 54, 61, 72, 73, 74, 75, 76, 78, 85, 87, and 94 of SEQ ID NO: 12.