Patent ID: 8173140

Claim:
A method for eliciting an antigen-independent, innate immune response against a microbial infection that is a bacterial infection or a viral infection in a subject, said method comprising administering to the subject an immunostimulatory composition in an amount sufficient to elicit an antigen-independent, innate immune response, wherein the method is performed in the absence of administering an immunogenic composition comprising an antigen that elicits an adaptive, antigen-specific, immune response, wherein the immunostimulatory composition consists of Proteosomes and liposaccharide, wherein Proteosomes are obtained from Neisseria species, and wherein the liposaccharide is obtained from the Neisseria species or from a different gram-negative bacteria species, and wherein the causative agent of the microbial infection is (a) different from the Neisseria species from which the Proteosomes are obtained and (b) different from the gram-negative bacteria species from which the liposaccharide is obtained.