Patent ID: 8629148

Claim:
A compound of the formula I in which X 1 is —O—, —O—CH 2 —, —O—C(═O)—, —NR 11 —, —NR 11 —CH 2 — or —NR 11 —C(═O)—; X 2 is a single bond, CO or CH 2 ; X 3 is N or CH; X 4 is N or CH; A is phenylene or 6-membered hetarylene with 1or 2 nitrogen atoms as ring members, where phenylene or hetarylene may be substituted by 1or 2 radicals R 10 ; R 1 and R 3 are independently of one another hydrogen, C 1 -C 3 -alkyl, C 1 -C 3 -fluoroalkyl, C 1 -C 3 -alkoxy, C 1 -C 3 -fluoroalkoxy, halogen or CN; R 2 is hydrogen or methoxy; where at least one of the radicals R 1 , R 2 and R 3 is hydrogen; R 4 is hydrogen or C 1 -C 4 -alkyl; R 5 is ethoxy, fluorinated ethoxy, fluoromethoxy, difluoromethoxy, trifluoromethoxy or isopropoxy; R 6 is hydrogen or methyl; R 7 is hydrogen, I, Br, Cl, F or CN; R 8 is hydrogen, I, Br, Cl, F or CN; R 9 is C 1 -C 3 -alkyl or C 1 -C 3 -fluoroalkyl; R 10 is C 1 -C 3 -alkyl, C 1 -C 3 -fluoroalkyl, C 1 -C 3 -alkoxy or C 1 -C 3 -fluoroalkoxy; R 11 is hydrogen, C 1 -C 4 -alkyl, C 1 -C 4 -fluoroalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -fluoroalkoxy; a is 0, 1or 2; and m and n are independently of one another 1or 2; or a pharmaceutically acceptable salt thereof.