Patent ID: 7884933

Claim:
A method to determine the concentration of analytes in tissues and samples, the method comprising: a. illuminating a tissue or a sample with a plurality of light wavelengths with one or more light emitters; b. measuring intensity values of light propagated from the tissue or sample at a plurality of distances from the one or more light emitters with at least one detector configured for detecting light, wherein light is measured at a first lateral distance and at a second lateral distance, wherein the first lateral distance is smaller than the second lateral distance; c. calculating one or more scattering coefficients μ s ′ for the plurality of light wavelengths based on the light intensity values measured at the first lateral distance independent of light intensity values measured at the second lateral distance; and d. calculating analyte concentrations using one or more of the scattering coefficients μ s ′ and using the intensity values at the plurality of light wavelengths measured at the second lateral distance without calculating scattering coefficients for the plurality of wavelengths based on the light intensity values measured at the second lateral distance.