Patent ID: 6894050

Claim:
A compound of Formula (IA) wherein Y is nitrogen; X and Z are each independently CR, where R for each occurrence is hydrogen, halogen, (C 1 -C 4 )alkyl, amino, or (C 1 -C 4 )alkylamino; W is amino, (C 1 -C 4 )alkylamino, or acetylamino; at least one of R 1a , R 1b , R 1d , and R 1e is independently selected from the group consisting of halogen, nitro, amino, (C 1 -C 4 )alkylamino, cyano, —C(O)NH 2 , (C 1 -C 4 )alkyl, halo-substituted(C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, and halo-substituted(C 1 -C 4 )alkoxy, or R 1a and R 1b taken together form a five- or six-membered, aromatic or partially or fully saturated fused ring, or R 1a taken together with R 2a or R 2b forms a five- or six-membered fully saturated fused ring; R 1c is hydrogen; R 2a and R 2b are each independently hydrogen, (C 1 -C 4 )alkyl, partially or fully saturated (C 3 -C 6 )cycloalkyl, or one of which taken together with R 1a forms a five- or six-membered, fully saturated fused ring; n is 0, 1, or 2; R 3a and R 3b are each independently hydrogen, halogen, (C 1 -C 4 )alkyl, or (C 1 -C 4 )alkyl substituted with hydroxy, fluoro, or (C 1 -C 4 )alkoxy; R 4 is hydrogen, hydroxy, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkyl substituted with hydroxy or cyano, (C 1 -C 4 )alkylcarbonyl, (C 1 -C 4 )alkoxy, (C 1 -C 4 )alkoxy-carbonyl, or (C 3 -C 4 )alkenyl; a nitrogen oxide thereof, a prodrug of said compound or said nitrogen oxide; a pharmaceutically acceptable salt of said compound, said nitrogen oxide, or said prodrug, or a solvate or hydrate of said compound, said nitrogen oxide, said prodrug, or said salt.