Patent ID: 7517871

Claim:
A compound having the structure set forth in Formula I: or a pharmaceutically acceptable salt thereof, wherein: A has the structure wherein each bond represented by a dashed and solid line in A represents a carbon-carbon single bond; a, b, c, and d are each carbon; e, f g, and h are each carbon; X is nitrogen; X′ is C; L is absent; each n is 1; Y is nitrogen; W is nitrogen; R 1 is hydrogen; R 2 , R 3 , and R 4 are each hydrogen; R 5 is selected from the group consisting of halogen, optionally substituted C 1-6 alkyl, optionally substituted C 1-6 alkyloxy, optionally substituted C 2-6 alkenyl, optionally substituted C 2-6 alkynyl, optionally substituted C 1-6 -alkoxyalkyl, optionally substituted C 1-6 alkylthio, perhaloalkyl, CN, COR 10 , CONHR 10 , NHCONHR 10 , SO 2 NHR 10 , SO 2 R 10 , OSO 2 R 10 , NO 2 , NHCOR 10 ; R 6 , R 7 , and R 9 are each hydrogen; R 8 is selected from the group consisting of halogen, optionally substituted C 1-6 alkyl, optionally substituted C 1-6 alkyloxy, optionally substituted C 2-6 alkenyl, optionally substituted C 2-6 alkynyl, optionally substituted C 1-6 -alkoxyalkyl, optionally substituted C 1-6 alkylthio, perhaloalkyl, CN, COR 10 , CONHR 10 , NHCONHR 10 , SO 2 NHR 10 , SO 2 R 10 , OSO 2 R 10 , NO 2 , NHCOR 10 ; Z is oxygen; R 10 is selected from the group consisting of hydrogen, optionally substituted C 1-6 alkyl, optionally substituted C 3-8 cycloalkyl, optionally substituted C 2-6 alkenyl, optionally substituted C 2-6 alkynyl, optionally substituted aryl, optionally substituted arylalkyl, and perhaloalkyl; and each bond represented by a dashed and solid line in Formula I represents a carbon-carbon double bond.