Patent ID: 7842471

Claim:
A method of detecting a bio-signal transmitter comprising the steps of: preparing transfected cells expressing a receptor specific to the bio-signal transmitter to be detected and an ion channel regulated by the receptor; culturing cells isolated from a sample to prepare a cell monolayer; plating and co-culturing the transfected cells on the cell monolayer; and measuring current change in the co-cultured transfected cells through an electrode attached to cells, to detect the presence of the bio-signal transmitter from the cultured cells from the sample in real time, wherein the receptor is GluR1, GluR1LY, GluR2, GluR3, GluR4, GluR5, GluR6, GluR7, or mGluR1-7 and the bio-signal transmitter is glutamate, or the receptor is NR1-1a/NR2A2D and the bio-signal transmitter is D-serine or glycine.