Patent ID: 7901689

Claim:
A chimeric peptide represented by formula (I) or formula (II), N-(S) m -(T h ) n (I) (T h ) n -(S) m -C (II) or chimeric peptides which are mixtures of formula (I) peptides, mixtures of formula (II) peptides, or mixtures of formula (I) and formula (II) peptides, wherein: N is the first 2, 3, 4, or 5 amino acid residues from the free N-terminus of a naturally-occurring amyloid β peptide that is formed by proteolytic cleavage of β amyloid precursor protein (βAPP); C is the last 2, 3, 4, or 5 amino acid residues from the free C-terminus of a naturally-occurring amyloid β peptide that is formed by proteolytic cleavage of β amyloid precursor protein (βAPP); T h is a promiscuous T helper cell epitope; S is a spacer amino acid residue; m is 0, 1, 2, 3, 4, or 5; and n is 1, 2, 3, or 4.