Patent ID: 6903095

Claim:
A method of treating Alzheimer's disease and senile dementia comprising administering to a patient in need of such treatment a therapeutically effective amount of at least one compound of the formula wherein x is —N═ or —CH═; R 1 is —CO—NR 5 R 6 ; —CHR 7 —(CH 2 ) n —CO—NR 5 R 6 ; —(CH 2 ) n —NR 5 R 6 ; —(CH 2 ) n —COOR 8 ; —(CH 2 ) n —CN; —CHR 7 —(CH 2 ) n —CF 3 ; —(CH 2 ) n —NH—COR 9 ; —(CH 2 ) n —NH—COOR 8 ; a heterocyclic ring group selected from —(CH 2 ) n -piperidinyl, —(CH 2 ) n -morpholinyl, —(CH 2 ) n -tetrahydrofuranyl; —(CH 2 ) n -thiophenyl or —(CH 2 ) n -isoxazolyl, wherein the heterocyclic ring may be substituted by C 1 -C 6 -alkyl; a phenyl; —(CH 2 ) n -phenyl, wherein the phenyl ring may be substituted by halogen or halogen-(C 1 -C 6 )-alkyl; —(CH 2 ) p —OR 8 ; —(CH 2 ) p —SR 8 ; —(CH 2 ) p —SO—R 9 ; or —(CH 2 ) n —CS—NR 5 R 6 ; R 2 is hydrogen; C 1 -C 6 -alkyl; —(CH 2 ) p —OR 10 ; —(CH 2 ) p —SR 10 ; or benzyl; R 3 is hydrogen or C 1 -C 6 -alkyl; R 4 is halogen, halogen-(C 1 -C 6 )-alkyl, cyano, C 1 -C 6 -alkoxy or halogen-(C 1 -C 6 )-alkoxy; R 5 and R 6 are independently from each other hydrogen or C 1 -C 6 -alkyl; R 7 is hydrogen, hydroxy or C 1 -C 6 -alkoxy; R 8 is hydrogen or C 1 -C 6 -alkyl; R 9 is C 1 -C 6 -alkyl; R 10 is hydrogen or C 1 -C 6 -alkyl; m is 1, 2 or 3; n is 0, 1 or 2; and p is 1 or 2; or a pharmaceutically acceptable salt thereof.