Patent ID: 6924301

Claim:
A method for treating arrhythmia of a mammal which comprises administration to said mammal in a pharmaceutically effective amount of a compound represented by the formula: wherein R 1 is an optionally substituted aralkyl, Z is —S— or —N(R 16 )—, wherein R 16 is a hydrogen atom or a lower alkyl; X 1 is —(CH 2 )s-N(R 18 )—CO—, wherein R 18 is a hydrogen atom or a lower alkyl, s is an integer from 0 to 3 or —CH 2 N(R 19 )COCHCH═CH—, wherein R 19 is a hydrogen atom or a lower alkyl; R 5 is an optionally substituted aryl, its prodrug, its pharmaceutically acceptable salt, or hydrate thereof.