Patent ID: 8541576

Claim:
A compound selected from the group consisting of: 1-(2-hydroxyethyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-tert-butyl-N-methyl-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-(2-aminoethyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 8-(methylsulfanyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-(2-hydroxyethyl)-8-[4-(4-methylpiperazin-1-yl)phenoxy]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-tert-butyl-8-[4-(4-methylpiperazin-1-yl)phenoxy]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-tert-butyl-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide 8-(methylsulfanyl)-1-(piperidin-4-yl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 8-(methylsulfanyl)-1-(piperidin-3-yl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 8-(methylsulfanyl)-1-(piperidin-3-ylmethyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 8-methoxy-1-(piperidin-4-yl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-[(3-exo)-8-azabicyclo[3.2.1]oct-3-yl]-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-(4-aminobutan-2-yl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-(1-azabicyclo[2.2.2]oct-3-yl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 8-(methylsulfanyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; 1-[trans-3-(hydroxymethyl)cyclobutyl]-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide; and 1-[cis-3-(hydroxymethyl)cyclobutyl]-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide.