Patent ID: 8247540

Claim:
A caged nucleotide and caged nucleotide analog comprising a caged purine or pyrimidine base selected from the group consisting of: wherein Z is a caging group of the formula: and wherein: R a , R b , R c and R d are each independently selected from the group consisting of H, halo, C 1 -C 20 alkyl, C 1 -C 20 alkenyl, C 1 -C 20 alkynyl, C 1 -C 20 alkoxy, aryl, heteroaryl, keto, carboxy, amino, silyl, boron, and targeting groups; or an adjacent pair of R a and R b , R b and R c , or R c and R d together form a substituent of the formula —O(CH 2 ) n O—, where n is from 1 to 3; and R e is selected from the group consisting of H, C 1 -C 20 alkyl, C 1 -C 20 alkenyl, C 1 -C 20 alkynyl, aryl, heteroaryl, keto, carboxy, and targeting groups; R f and R g are each independently selected from the group consisting of consisting of H, C 1 -C 20 alkyl, C 1 -C 20 alkenyl, C 1 -C 20 alkynyl, C 1 -C 20 alkoxy, aryl, heteroaryl, keto, carboxy, amino, and targeting groups.