Patent ID: 8029978

Claim:
A processing method for the long-term stabilization of biological red blood cell volume, comprising: contacting red blood cells in a blood sample with a processing solution comprising a membrane-fixation reagent and an aldehyde, wherein the membrane-fixation reagent is selected from a group consisting of dichromate salts, picric acid and salts of cadmium, wherein the membrane fixation reagent is added such that the concentration in the processing solution is 0.02%-0.5% (w/v), and wherein the aldehyde is selected from a group consisting of formaldehyde, paraformaldehyde, glutaraldehyde, olefine aldehyde and combinations thereof; and stabilizing the red blood cell volume in the blood sample with a coefficient of variation of 1.32% or less for over 30 days, excluding a changing period of the first 5 days.