Patent ID: 7220777

Claim:
A compound of formula (I) comprising: or a salt thereof, wherein M is a group selected from the group consisting of O, S, C═O, NH and CH 2 ; L is a 2- or 3-membered alkylene chain; wherein together M-L may be optionally substituted by at least one moiety selected from the group consisting of methyl, ethyl, hydroxy and C 1-3 alkoxy; R 1 and R 2 together with the nitrogen atom to which they are bonded form a pyrrolidinyl; each R 6 is the same or different and is independently selected from the group consisting of hydroxy, C 1-2 alkyl, C 1-3 alkoxy, halo, C 2-3 alkenyl, benzyl, and —C(R a )NOR b , wherein R a and R b are each independently selected from the group consisting of hydrogen, methyl, methoxymethyl, methoxymethoxy, and methoxyethoxy and n is 1, 2, 3, or 4; QY is isoindole-1,3-dione; shown below as Z is bound to the Q ring and is selected from the group consisting of a direct bond, NH, NCH 3 , O, S, and CH 2 ; and R 3 is a group selected from the group consisting of aryl, alk-2-en-1-yl, cycloalkyl and cycloalk-2-en-1-yl and wherein said aryl, alk-2-en-1-yl, cycloalkyl, and cycloalk-2-en-1-yl are optionally substituted from 1 to 3 times with a substituent selected from the group consisting of C 1-3 alkyl, halo, amino, alkylamino, dialkylamino, hydroxy, C 1-3 alkoxy, cyano, trifluoromethyl, and methylthio groups.