Patent ID: 8440167

Claim:
A LOX-1 imaging composition, said LOX-1 imaging composition comprises a plurality of liposome having a mean diameter of less than 100 nm, said liposomes comprising 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, cholesterol, N-hydroxysuccinimide ester of carboxy-PEG3400-DSPE-LOX-1 antibody, and at least one additional polymer selected from the group consisting of 1,1′dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate, diethylenetriaminepentaacetic acid α,ω-bis(8-stearoylamido-3,6-diaoxaoctylamide) gadolinium complex and DTPA-phosphatidylethanolamine-SPECT contrast agent; and a pharmaceutically acceptable carrier.