Patent ID: 8426587

Claim:
A compound of formula I: or stereoisomers, enantiomers, diastereoisomers, or pharmaceutically acceptable salts thereof; wherein: R 1 is hydrogen or lower alkyl; R 2 is hydrogen, substituted or unsubstituted lower alkyl; R 3 and R 4 are independently fluorine or —CH 2 —O—R 5 —R 6 ; provided, however, that one of R 3 and R 4 is fluorine, but both R 3 and R 4 are not fluorine at the same time; R 5 is substituted or unsubstituted aryl; and R 6 is hydrogen or R 6 is selected from the group consisting of: wherein: each of R 7 and R 8 are independently hydrogen, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted alkylaryl, or substituted or unsubstituted alkylheteroaryl; or R 7 and R 8 may cooperate to form a substituted or unsubstituted cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl ring system; R 9 is hydrogen, amido, carboximido, lower alkylamido, cycloalkylamido, lower alkylcarboximido, or cycloalkylcarboximido; each of R 10 and R 11 are independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, or substituted or unsubstituted alkynyl; and R 12 is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted alkylaryl, substituted or unsubstituted alkylheteroaryl, amido, carboximido, lower alkylamido, cycloalkylamido, lower alkylcarboximido, or cycloalkylcarboximido.