Patent ID: 7348315

Claim:
A method comprising the steps of identifying an animal in need of treatment for heart failure; and administering to said animal a compound of the following formula or a pharmaceutically acceptable salt thereof in an amount effective to treat said heart failure: wherein R 1 is halogen or —R 6 —(R 7 ) p —R 8 ; R 2 is hydrogen, alkyl, cycloalkyl, cycloalkenyl, alkynyl, alkylthio, aminoalkylthio, halogen, or —R 6 —(R 7 ) p —R 8 ; R 3 is H, halogen or —R 6 —(R 7 ) p —R 8 ; R 4 is —OH or —SH; R 5 is —OH or acetamido; R 6 is NH or S; R 7 is CH 2 ; R 8 is H, NH 2 , halogen, CN, CCH, cycloalkyl, having 3 to about 10 carbon atoms or aryl having 3 to about 20 carbon atoms; R 9 is OH; R 10 and R 11 are independently hydrogen or halogen; X, Y, and Z are; m is 0, 1, or 2; n is 0 or 1; q is 0 or 1 with the proviso that when q is 0, then R 2 is alkyl, cycloalkyl, cycloalkenyl, alkynyl, halogen, or —R 6 —(R 7 ) p —R 8 where R 6 is NH, provided that at least one of m, n, and q is 1; and p is 0 to 10.