Patent ID: 7022721

Claim:
A composition for the treatment of hair, nail, ex-vivo organ, ex-vivo cell or ex-vivo tissue to improve the biomechanical and diffusional characteristics comprising an effective amount of a compound selected form the group consisting of compounds of the formula (I): wherein R′ is a C 1 –C 18 alkyl group —CH(R 5 )—OH, or the group —CH(R 5 )—OC(═O)—R 6 wherein R 5 is a C 1-18 alkyl group and R 6 is selected from the group consisting of C 1 –C 18 alkyl, phenyl, halosubstituted phenyl, C 1 –C 18 alkoxysubstituted phenyl and naphthyl; R 2 is selected from the group consisting of hydroxy, phenyl, halosubstituted phenyl, C 1 –C 18 alkoxysubstituted phenyl, a C 5-7 aromatic, unsaturated or saturated heterocyclic ring having one to three heteroatoms selected from the group consisting of N, O and S; R 3 and R 4 together with their ring atoms may be an aromatic ring system of 6–10 carbons, optionally substituted with one or more halo, lower alkyl, lower alkoxy, or amino groups; and X − is halide or other pharmaceutically acceptable anion.