Patent ID: 7056921

Claim:
A compound having the formula (I) wherein X is N; Y is CH 2 NR 2 , NR 2 CO, CONR 2 , NR 2 SO 2 or NR 2 CONR 2 wherein R 2 is H or C 1 –C 6 alkyl; R 1 is H, C 1 –C 6 alkyl or C 3 –C 6 cycloalkyl; R 3 is (CH 2 ) n -phenyl, wherein phenyl is monosubstituted with R 4 or disubstituted with R 4 and R 5 ; wherein R 4 is selected from a) an optionally substituted 5-, 6- or 7-membered heterocyclic ring containing one or two heteroatoms selected from N, O, S, SO and SO 2 , wherein when the heterocyclic ring is 5- or 6-membered and contains one heteroatom, the heteroatom is not N and when the heterocyclic ring is 5- or 6-membered and contains two heteroatoms, the heteroatoms are not both N and wherein the substituent(s) is (are) selected from C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl, phenyl-C 1 –C 6 alkyl, (CH 2 ) m OR 9 wherein in is 2–6 and R 9 is H, C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl or phenyl-C 1 –C 6 alkyl, and COR 8 , and b) an optionally substituted 5- or 6-membered heteroaromatic ring containing one or two heteroatoms selected from N, O and S wherein when the heteroaromatic ring contains one heteroatom, the heteroatom is not N and when the heteroaromatic ring contains two heteroatoms, the heteratoms are not both N and wherein the substituent(s) is (are) selected from C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl and phenyl-C 1 –C 6 alkyl; R 5 is selected from OH, CF 3 , OCF 3 , halogen, C 1 –C 6 alkyl and C 1 –C 6 alkoxy; and n is 0–4; wherein the compound is an (R)-enantiomer, an (S)-enantiomer, or a racemate in the form of a free base or a pharmaceutically acceptable salt or solvate thereof.