Patent ID: 8231877

Claim:
A method of treating mycosis fungoides, comprising administering to a subject in need thereof a sufficient amount of a monoclonal antibody, or antigen binding portion thereof, which binds to human CD4, comprising: (a) a heavy chain variable region having a CDR1 comprising the amino acid sequence encoded by bases 148-162 of SEQ ID NO:205; (b) a CDR2 comprising the amino acid sequence encoded by bases 205-252 of SEQ ID NO:205; and (c) a CDR3 comprising the amino acid sequence encoded by bases 349-369 of SEQ ID NO:205; and a light chain variable region having (a) a CDR1 comprising the amino acid sequence encoded by bases 136-168 of SEQ ID NO:206; (b) a CDR2 comprising the amino acid sequence encoded by bases 214-234 of SEQ ID NO:206; and (c) a CDR3 comprising the amino acid sequence encoded by bases 331-357 of SEQ ID NO:206.