Patent ID: 6964965

Claim:
A compound of Formula I, or a stereoisomer thereof or a phannaceutically acceptable salt thereof, wherein in Formula I: R 1 and R 2 are independently selected from halogen, —NO 2 , —CN, —R a , —OR a , —S(O) m R a , —NR a R a , —C(O)NR a R a , —C(S)NR a R a , —S(O) m NR a R a , —NR a S(O) m R a , —NR a C(O)OR a , —NR a C(S)OR a , —OC(O)NR a R a , —OC(S)NR a R a , —NR a C(O)NR a R a , —NR a C(S)NR a R a , —C(O)OR a , —C(S)OR a , —OC(O)OR a , or —CR a R a Ar; X is selected from —NR 3 R 4 , —OR 3 , —CR 3 R 4 R 5 , —C(O)R 3 , —C(S)R 3 , —S(O) m R 3 , —NR 3 C(O)R 4 , —NR 3 C(S)R 4 , —NR 3 S(O) m R 4 , or —R 3 ; R 3 , R 4 , and R 5 are independently selected from R a , substituted alkyl, substituted aryl, substituted heteroaryl, substituted cycloalkyl, substituted heterocycloalkyl, aryl cycloalkyl, substituted aryl cycloalkyl, heteroaryl cycloalkyl, substituted heteroaryl cycloalkyl, aryl heterocycloalkyl, substituted aryl heterocycloalkyl, heteroaryl heterocycloalkyl, or substituted heteroaryl heterocycloalkyl; R a each is selected from H, alkyl, cycloalkyl, haloalkyl, aryl, heteroaryl, or heterocycloalkyl, where each instance of R a may be optionally substituted with 1 to 5 of R t , —OR t , —S(O) m R t , —NR t R t , oxo (═O), thione (═S); R t each is selected from H, halogen, —NO 2 , —NH 2 , —OH, —SH, —CN, —C(O)NH 2 , —C(S)NH 2 , —C(O)NHalkyl, —C(S)NHalkyl, —C(O)Nalkylalkyl, —C(S)Nalkylalkyl, —OaIkyl, —NHalkyl, —Nalkylalkyl, —S(O) m alkyl, —SO 2 NH 2 , —SO 2 NHalkyl and —SO 2 Nalkylalkyl, alkyl, cycloalkyl, haloalkyl, phenyl, benzyl, heteroaryl, or heterocycloalkyl where phenyl, benzyl, heteroaryl, and heterocycloalkyl may be optionally substituted with alkyl or halogen; G is selected from wherein each G group may have from 1 to 6 substituents independently selected from halogen, —CN, —NO 2 , oxo (═O), thione (═S), —OR 5 , —SR 5 , —NR 5 R 5 , —C(O)R 5 , —C(S)R 5 , —C(O)OR 5 , —C(S)OR 5 , —C(O)NR 5 R 5 , —C(S)NR 5 R 5 , —S(O) m R 5 , —S(O) 2 NR 5 R 5 , —NR 5 C(O)R 5 , —NR 5 C(S)R 5 , —NR 5 C(O)OR 5 , —NR 5 C(S)OR 5 , —NR 5 C(O)NR 5 R 5 , —NR 5 C(S)NR 5 R 5 , —NR 5 S(O) 2 R 5 —OC(O)R 5 , —OC(S)R 5 , —OC(O)OR 5 , —OC(S)OR 5 , —OC(O)NR 5 R 5 , —OC(S)NR 5 R 5 , —CR 5 R 5 Ar, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, or substituted heterocycloalkyl, and wherein each G group may contain up to one double bond in its non-aromatic ring; Ar is selected from aryl, substituted aryl, heteroaryl and substituted heteroaryl; m is 0, 1 or 2; and n is 0, 1, or 2.