Patent ID: 8546578

Claim:
A compound of Formula (1): wherein: Ar is a substituted or unsubstituted aryl or heteroaryl ring system; X is either a moiety wherein the pKa of the acid H—X is less than 12 or a leaving group; R 1 is hydrogen or a substituent having a Hammett σ p value of less than zero; and R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 are independently selected from the group consisting of: H, CF 3 , OCF 3 , CN, hydroxyl, amino, aminoalkyl, (CH 2 ) n N(CH 2 ) m , —SR 8 , —SOR 8 , halo, SO 2 R 8 , (CH 2 ) n OR 8 , C(═O)NR 8 R 9 , SO 2 NR 8 R 9 , NR 8 SO 2 R 9 , COOR 8 , NR 8 C(═O)R 9 , NR 8 C(═O)NR 9 , SO 2 R 8 , (CH 2 ) n C(═O)NR 8 R 9 , (CH 2 ) n SO 2 NR 8 R 9 , (CH 2 ) n NR 8 SO 2 R 9 , (CH 2 ) n COOR 8 , (CH 2 ) n NR 8 C(═O)R 9 , (CH 2 ) n NR 8 C(═O)NR 9 , alkoxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; each m and n is independently an integer from 0 to 10; and each R 8 and R 9 are independently chosen from H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl.