Patent ID: 6989022

Claim:
A method of closing a wound in an artery in a patient, the method comprising the steps of: treating a blood fluid with an anticoagulant inhibiting agent during a first time period to prevent inhibition of a clotting cascade from initiating during a second time period subsequent to the first time period; treating the blood fluid with a procoagulating agent in the second time period to initiate a clotting cascade such that at least a portion of the blood fluid will form a clot of blood during a third time period subsequent to the second time period, the blood fluid containing sufficient blood components to enable a portion of the blood fluid to clot during the third time period subsequent to the initiation of the clotting cascade during the second time period; transporting the treated blood fluid to the wound in the patient such that the blood fluid comes into contact with the patient proximate the wound; and applying pressure to the artery proximal the wound to limit blood flow through the artery so that the clotting cascade comes generally to a conclusion and a clot forms proximate the wound to prevent blood in the artery from passing through the wound.