Patent ID: 7968730

Claim:
A method for the manufacture of a compound of the formula I defined below, comprising a method for the manufacture of esters of the formula I, wherein n is a number from 0 to 4, each R 1 is, independently of the other substituents R 1 , unsubstituted or substituted alkyl, unsubstituted or substituted aryl, unsubstituted or substituted heterocyclyl, alkylsulfonyl, sulfonyl alkyl, N-mono- or N,N-disubstituted or unsubstituted aminosulfonyl alkyl, hydroxy, mercapto, nitro, halogen, cyano, carboxamido, N-mono- or N,N-disubstituted carboxamido, carboxhydrazido, unsubstituted or substituted alkoxycarbonyl, unsubstituted or substituted alkoxy, formyl or other alkanoyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted cycloalkyl, alkanoyloxy, N-mono- or N,N-disubstituted or unsubstituted amino, unsubstituted or substituted hydrazino, or is a residue of a boronic acid or an ester thereof; R2 is hydrogen or unsubstituted or substituted alkyl, unsubstituted or substituted alkoxycarbonyl, unsubstituted or substituted arylsulfonyl, unsubstituted or substituted alkylsulfonyl, unsubstituted or substituted aryl, carbamoyl or N-mono- or N,N-disubstituted carbamoyl, silyl substituted by three moieties independently selected from unsubstituted or substituted alkyl and substituted or unsubstituted aryl, or acyl, and R′ is unsubstituted or substituted alkyl, where a starting material of the formula III, wherein n, R 1 and R2 have the meanings given under formula I and NB is a tertiary nitrogen base where the nitrogen is not part of a ring, is reacted (a) for the synthesis of an ester of the formula I with an active carbonic ester of the formula IV, wherein X is halogen and R′ is as defined under formula I, to give the corresponding ester of the formula I.