Patent ID: 8129414

Claim:
A method of treating a subject afflicted with an ailment selected from the group consisting of cerebral ischemias, strokes, traumatic brain injuries, neuronal tumors, Alzheimer's disease, Parkinson's disease, epilepsy, schizophrenias, acute neuropathic pain, chronic neuropathic pain, drug addictions, depression, ethanol withdrawal, anxiety, and memory disorders, the method comprising: administering to the subject, for a time and in an amount sufficient to alleviate at least one symptom associated with the ailment, an NMDA receptor antagonist having a chemical structure selected from the group consisting of Structures A, B, and C, or an enantiomer, a racemic mixture of enantiomers, a non-racemic mixture of enantiomers, a diastereomer, or a mixture of diastereomers thereof, wherein R of Structure A is selected from the group consisting of, a hydroxyl group and an amino group, wherein R of Structures B and C is selected from the group consisting of a halo moiety, a nitrate group, a halomethyl group, a nitro moiety, an acyl moiety, a formyl moiety, an alkylsulfonyl moiety, an arylsulfonyl moiety, a cyano moiety, a hydroxyl group, and an amino group, and wherein one or more hydrogen atoms of the polycyclic ring of the antagonist are independently optionally replaced with a lower alkyl group.