Patent ID: 7655639

Claim:
A minimally invasive clinical method for closing the spatial void of an umbilical hernia in a living subject using a polysaccharide delivery device, said method comprising the steps of: obtaining a prepared-in-advance polysaccharide gel composition consisting essentially of dextran particles and hyaluronic acid as the active ingredients and in which there is a complete absence of preformed collagen and elastin fibers; percutaneously introducing, by the polysaccharide delivery device, a predetermined quantity of said prepared in-advance polysaccharide gel composition to the anatomic locale of the umbilical hernia; inducing an ingrowth of fibroblasts at the anatomic locale of the umbilical hernia using said introduced polysaccharide gel composition; generating newly formed fibers in-situ at the anatomic locale of the umbilical hernia using said ingrowth of fibroblasts; forming and aggregating said newly formed fibers in-situ; and occluding and filling said spatial void to substantially close the umbilical hernia by said newly formed fibers generated in-situ at the anatomic locale of the umbilical hernia.