Patent ID: 8138194

Claim:
A compound of formula (I): wherein one of the two bonds is a single bond and the other is a double bond; X 1 is NR a and X 2 is CR 2 , in which R a is H, alkyl, alkenyl, alkynyl, aryl, or heteroaryl; each of Y and Z, independently, is O, S, or NR b , in which R b is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, cyano, or NO 2 ; each of R 1 and R 2 , independently, is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, halo, C(O)OR c , or C(O)NR c R d , in which each of R c and R d , independently, is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; each of R 3 and R 4 , independently, is H, halo, nitro, cyano, amino, hydroxy, alkoxy, aryloxy, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl, or heteroaryl; A is arylene or heteroarylene; B is O, S, or NR e , in which R e is H, alkyl, alkenyl, or alkynyl; C is O, S, alkylene, or NR f , in which R f is H, alkyl, alkenyl, or alkynyl; or B and C, together with the carbon atom to which they are bonded, are heterocycloalkyl or heterocycloalkenyl; D is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; or C and D together are heterocycloalkyl, heterocycloalkenyl, aryl or heteroaryl; and n is 1, 2, 3, or 4.