Patent ID: 7799924

Claim:
A compound of the general formula (I): wherein R 1 is C 1-6 -alkyl which may optionally be substituted with one or more substituents independently selected from R 11 , wherein R 11 is halogen, C 1-6 -alkoxy or hydroxy, r is 1, s is 0, 1, 2 or 3, t is 0, 1, 2 or 3, X is C═O, CHOH or CR 2 R 3 ; wherein R 2 and R 3 independently are hydrogen or C 1-6 -alkyl, or X is a bond, Y is selected from the group consisting of oxadiazolyl, thiadiazolyl, and triazolyl, optionally substituted with one or more substituents independently selected from R 18 , R 18 is halogen, nitro, cyano, hydroxy, C 1-6 -alkyl, C 1-6 -alkylthio or C 1-6 -alkoxy, R 4 is biphenyl, which may optionally be substituted with one or more substituents independently selected from R 14 , wherein R 14 is selected from the group consisting of halogen, acyl, hydroxy, C 1-6 -alkyl, C 1-6 -alkylthio, C 1-6 -alkylsulfonyl, C 1-6 -alkoxy, C 3-8 -cycloalkyl, halo-C 1-6 -alkyl, halo-C 1-6 -alkoxy, piperidinyl alkyl optionally substituted with phenyl, and piperazinyl alkyl optionally substituted with alkyl; as well as any diastereomer or enantiomer or tautomeric form, mixtures of these, or a pharmaceutically acceptable salt thereof.