Patent ID: 8344137

Claim:
A compound of formula (I) wherein R 1 is selected from the group consisting of: hydrogen, halogen, carboxyl, alkoxycarbonyl, alkylsulfonylaminocarbonyl and cycloalkylsulfonylaminocarbonyl; R 2 is selected from the group consisting of: hydrogen, halogen and carboxyl; R 3 is carboxyl; R 4 is selected from the group consisting of: hydrogen, carboxyl, alkylsulfonylaminocarbonyl and cycloalkylsulfonylaminocarbonyl; and R 5 is selected from the group consisting of: pyridinyl, substituted pyridinyl, morpholinylpyridinyl, phenyl and substituted phenyl wherein substituted pyridinyl and substituted phenyl are pyridinyl and phenyl substituted with one or two substituents independently selected from the group consisting of halogen, halophenyl, alkyl, cycloalkyl, alkoxy, cyano, carboxyl, cycloalkylcarbonylamino, alkylsulfonylamino, phenylsulfonylamino, phenylaminosulfonyl, halophenylsulfonylamino, phenyl, alkylphenyl, alkoxyphenyl, cyanophenyl, alkylaminocarbonylphenyl, alkylsulfonylphenyl, pyrrolidinyl, pyridinylcarbonylamino, morpholinyl, alkylmorpholinyl, piperazinyl, alkylpiperazinyl, alkylcarbonylpiperazinyl, alkylphenylpiperazinyl, halophenylpiperazinyl, oxopyrrolidinyl, dioxoimidazolidinyl, oxoimidazolidinyl, alkyloxoimidazolidinyl, phenyloxoimidazolidinyl, 2-oxo-oxazolidin-3-yl, alkyl-2-oxo-oxazolidin-3-yl, phenylalkyl-2-oxo-oxazolidin-3-yl, dioxopiperazinyl, alkyldioxopiperazinyl, aminocarbonyl, alkylaminocarbonyl, alkoxyalkylaminocarbonyl, alkylaminoalkylaminocarbonyl, cycloalkylaminocarbonyl, alkylpyrrolidinylaminocarbonyl, tetrahydrofuranylaminocarbonyl, alkylpyrrolidinylalkylaminocarbonyl, alkoxycarbonylazetidinylaminocarbonyl, pyrrolidinylcarbonyl, piperidinylcarbonyl, alkylsulfonylaminocarbonyl, cycloaklylsulfonylaminocarbonyl, phenylsulfonylaminocarbonyl, alkylazetidinylaminocarbonyl, haloazetidinyl, alkylpyrrolidinylaminocarbonyl, phenylaminocarbonyl, pyrazinylaminocarbonyl, aminoalkoxyalkyl, aminoalkoxy, carboxylalkoxy, carboxylalkoxyalkyl, alkyltetrazolyl, phenylalkyltetrazolyl, alkylaminosulfonyl, alkylphenylsulfonylamino, alkylcarbonylamino, cycloalkenylcarbonylamino, phenylcarbonylamino, phenylalkylcarbonylamino, alkylaminoalkylamino, 7-benzyl-4-oxo-5,6,7,8-tetrahydro-4H-pyrido[3,4-d]pyrimidin-3-yl, alkylaminophenyl, alkylamino, hydroxyalkylamino, carboxylalkylamino, carboxylcycloalkylamino, alkylaminocarbonylalkylamino, aminocarbonyl(alkyl)amino, morpholinylcarbonylalkylamino, alkylpiperazinylcarbonylalkylamino, alkylaminosulfonylamino, alkylcarbonylaminophenylsulfonylamino, alkylaminocarbonylamino, aminocarbonylamino, morpholinylcarbonylamino, pyrrolidinylcarbonylamino, piperidinylcarbonylamino, alkylpiperazinylcarbonylamino, phenylalkylaminocarbonylamino, halophenylcarbonylamino, halophenylaminocarbonylamino, pyrazinylcarbonylamino, alkylpiperazinyl, pyrrolidinylsulfonyl and alkylpyrrolidinylaminosulfonyl; or a pharmaceutically acceptable salt or ester thereof.