Patent ID: 7442715

Claim:
A method for treating retinopathy comprising: administering to a subject in need thereof in an amount effective to treat retinopathy a compound of formula (I): wherein the 1,3-thiazole ring is optionally substituted at the 5-position; Y is lower alkylene, lower alkenylene, or —CONH—; and Z is a group of the formula: wherein R 2 is a group of the formula: -A-B-D-E, wherein A is a bond, lower alkylene, —NH— or —SO 2 —; B is a bond, lower alkylene, —CO— or —O—; D is a bond, lower alkylene, —NH— or —CH 2 NH—; provided that B and D are not both simultaneously bonds, and E is amino, which may be optionally protected, —N═CH 2 , wherein Q is —S— or —NH—; and R 3 is hydrogen, lower alkyl, lower alkylthio, or —NH—R 4 , wherein R 4 is hydrogen, —NH 2 , or lower alkyl; or a pharmaceutically acceptable salt thereof.