Patent ID: 8329157

Claim:
A composition comprising a blend or mixture of (i) a polymer comprising a poly(hydroxyalkanoate) and (ii) a bioactive agent, wherein the polymer is represented by a formula: wherein the ratio of A:B is less than, greater than, or equal to one; A comprises B comprises a poly(ester amide) where R 1 is selected from a group consisting of alkylenes, alkanoates, alkyl alkanoates, diesters, acylals, diacids, saturated fatty acids, glycerides, and combinations thereof; R 2 is selected from a group consisting of hydrogen, substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and substituted, unsubstituted, and hetero-aromatic radicals; R 3 is selected from a group consisting of hydrogen; substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and substituted, unsubstituted, and hetero-aromatic radicals; R 4 is selected from a group consisting of hydrogen, substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and substituted, unsubstituted, and hetero-aromatic radicals; R 6 is optional and is selected from a group consisting of substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and substituted, unsubstituted, and hetero-aromatic radicals; R 8 is selected from a group consisting of substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and substituted, unsubstituted, and hetero-aromatic radicals; R 11 through R 14 are independently selected from a group consisting of hydrogen; substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and substituted, unsubstituted, and hetero-, aromatic radicals; L 1 is a linkage connecting A to B; X is a biobeneficial agent; L 2 is a linkage connecting X to said polymer; k is an integer; m is an integer from about 1 to about 40; and n, p, and z are integers not equal to zero, and wherein the biobeneficial agent comprises a component selected from a group consisting of phosphorylcholine, poly(N-vinyl pyrrolidone), poly(acrylamide methyl propane sulfonic acid), poly(styrene sulfonate), polysaccharides, poly(ester amides), non-thrombotics, antimicrobials, and combinations thereof.