Patent ID: 7994192

Claim:
A compound of formula (I): in which: R 1 is selected from halo, cyano, hydroxyl, (C 1-6 )alkyl (optionally substituted by halo, hydroxyl, amino, mono to perfluoro(C 1-3 )alkyl, carboxy, or (C 1-6 )alkoxycarbonyl), (C 3-7 )cycloalkyl, (C 1-6 )alkoxy, amino, mono- or di-(C 1-6 )alkylamino, acylamino, carboxy, (C 1-6 )alkoxycarbonyl, carboxy(C 1-6 )alkyloxy, (C 1-6 )alkylthio, (C 1-6 )alkylsulphinyl, (C 1-6 )alkylsulphonyl, sulphamoyl, mono- and di(C 1-6 )alkylsulphamoyl, carbamoyl, mono- and di-(C 1-6 )alkylcarbamoyl, and heterocyclyl; Y is a linker group having from one to six methylene groups in a straight chain and in which one or more methylene groups may have one or more (C 1-6 ) alkyl, (C 1-6 )alkoxy or (C 1-6 )alkylidenyl substituents; R 2 is selected from halo, cyano, hydroxyl, (C 1-6 )alkyl (optionally substituted by halo, hydroxyl, amino, mono to perfluoro(C 1-3 )alkyl, carboxy, or (C 1-6 )alkoxycarbonyl), (C 3-7 )cycloalkyl, (C 1-6 )alkoxy, amino, mono- or di-(C 1-6 )alkylamino, acylamino, carboxy, (C 1-6 )alkoxycarbonyl, carboxy(C 1-6 )alkyloxy, (C 1-6 )alkylthio, (C 1-6 )alkylsulphinyl, (C 1-6 )alkylsulphonyl, sulphamoyl, mono- and di(C 1-6 )alkylsulphamoyl, carbamoyl, mono- and di-(C 1-6 )alkylcarbamoyl, and heterocyclyl; when Z 1 is S, Z 2 and Z 3 are CH; when Z 2 is S, Z 1 and Z 3 are CH; when Z 3 is S, Z 1 and Z 2 are CH; X is NH, S, SO, SO 2 ,O or CH 2 ; n is one, two or three; and m is 0 or an integer from 1 to 4.