Patent ID: 8496835

Claim:
A displacement chromatography process, comprising: loading onto a stationary phase comprising an anion-exchange material a mixture comprising one or more component to be separated; displacing at least one of the one or more component from the stationary phase by applying to the stationary phase a mixture comprising a polyaromatic polyanionic displacer compound having the general formula: Cen(Ar) w wherein Cen=a bond, an alkenyl group, an alkynyl group, a benzene ring, a biphenylene, a naphthylene, or wherein: R=independently —H, C 1 -C 4 alkyl, or C 1 -C 4 hydroxyalkyl; Z=independently —H, halogen, —OH, —OR, —NRCH 2 CH(OH)CH 2 OH, —NR 2 , —N[CH 2 CH(OH)CH 2 OH] 2 , —NRC(CH 2 OH) 3 , —NRCH(CH 2 OH) 2 , or —N(R)(poly(alkylene oxide)); w=2 to the highest number of substitutable positions on Cen; and Ar=(a), (b) and/or (c); and wherein, in the following (a), (b) and (c): An − =independently sulfonate, phosphonate, phosphinate, phosphate, a phosphate mono- or di-ester, sulfate, a sulfate mono-ester; or boronate; G=independently H, C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 6 -C 10 aryl, halogen, nitro, hydroxy, C 1 -C 6 alkoxy, cyano, —NH 2 , —NRH, —NR 2 , —NHC(O)R, —CHO, —C(O)R; and (a), (b) and (c) are: