Patent ID: 8110361

Claim:
A method for detecting and/or classifying a colorectal cancer belonging to a distinct colorectal cancer subgroup having frequent CpG island hypermethylation (CIMP colorectal cancer), comprising: determining, by analyzing a human subject biological sample comprising colon cancer cell genomic DNA, a CpG methylation status of at least one gene or genomic sequence selected from the NEUROG1 sequence group consisting of NEUROG1, SEQ ID NOS:138, 124 and 110, wherein CpG hypermethylation, relative to normal controls, is indicative of a colorectal cancer belonging to a distinct colorectal cancer subgroup having frequent CpG island hypermethylation (CIMP colorectal cancer), wherein a method for detecting and/or classifying a CIMP colorectal cancer is afforded.