Patent ID: 7582628

Claim:
A method for treating cell proliferative disorders caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I) wherein R is hydrogen or methyl; R 1 is an alkoxy group; R 2 is a hydrogen or halogen atom; X is a divalent group selected from methylene (—CH 2 —) or fluoromethylene (—CHF—), or it is a heteroatom or heteroatomic group selected from oxygen (—O—) or nitrogen (—NR′—) wherein R′ is a hydrogen atom, a straight or branched C 1 -C 4 alkyl group or a C 3 -C 6 cycloalkyl group; or a pharmaceutically acceptable salt thereof; wherein said cell proliferative disorders are selected from the group consisting of benign prostate hyperplasia, familial adenomatosis polyposis, neuro-fibromatosis, melanoma, teratocarcinoma, xeroderma pigmentosum, keratoxanthoma, Kaposi's sarcoma, colon cancer, lung cancer, osterosarcoma, hematopoietic tumors of myeloid or lymphoid lineage, mesothelioma, kidney cancer, breast cancer, ovary cancer, pancreas cancer, prostate cancer, thyroid, and cervix cancer.