Patent ID: 7250398

Claim:
An isolated polypeptide having antimicrobial activity, having the amino acid sequence (SEQ ID NO: 354): Xaa Xaa Xaa Pro Pro Xaa Xaa Pro Arg Xaa Xaa Pro Xaa 1 5 10 Xaa Pro Pro Pro Xaa Xaa Pro Arg Xaa Xaa Pro Xaa Xaa 15 20 25 Pro wherein (a) Xaa Xaa Xaa at positions 1-3 is absent or is Arg-Xaa-Arg wherein Xaa at position 2 is Phe, Ile, Leu, Arg, or Val; (b) Xaa Xaa at positions 6-7 is selected from the group consisting of Arg-Phe, Phe-Arg, Arg-Leu, Leu-Arg, Arg-Val, Val-Arg, Arg-Ile, and Ile-Arg, (c) Xaa Xaa at positions 10-11 is selected from the group consisting of Phe-Pro, Pro-Phe, Leu-Pro, Pro-Leu, Val-Pro, Pro-Val, Ile-Pro, and Pro-Ile. (d) Xaa Xaa at positions 13-14 is selected from the group consisting of Arg-Phe, Phe-Arg, Arg-Leu, Leu-Arg, Arg-Val, Val-Arg, Arg-Ile, and Ile-Arg, (e) Xaa Xaa at positions 18-19 is selected from the group consisting of Arg-Phe, Phe-Arg, Arg-Leu, Leu-Arg, Arg-Val, Val-Arg, Arg-Ile, and Ile-Arg, (f) Xaa Xaa at positions 22-23 is selected from the group consisting of Phe-Pro, Pro-Phe, Leu-Pro, Pro-Leu, Val-Pro, Pro-Val, Ile-Pro, and Pro-Ile, (g) Xaa Xaa at positions 25-26 is selected from the group consisting of Arg-Phe, Phe-Arg, Arg-Leu, Leu-Arg, Arg-Val, Val-Arg, Arg-Ile, and Ile-Arg.