Patent ID: 7947716

Claim:
A method of immobilizing an amine-containing material to a substrate, said method comprising: selecting a compound of Formula I wherein X 1 is a substrate-reactive functional group selected from a carboxy, halocarbonyl, halocarbonyloxy, cyano, hydroxy, mercapto, isocyanato, halosilyl, alkoxysilyl, acyloxysilyl, azido, aziridinyl, haloalkyl, tertiary amino, primary aromatic amino, secondary aromatic amino, disulfide, alkyl disulfide, benzotriazolyl, phosphono, phosphoroamido, or phosphato; Y 1 is a single bond or a divalent group selected from an alkylene, heteroalkylene, arylene, carbonyl, carbonyloxy, carbonylimino, oxy, thio, —NR d — where R d is hydrogen or alkyl, or combinations thereof; Z 1 is an alkyl, aryl, or —(CO)R a wherein R a together with R 1 with groups to which they are attached form a four to eight membered heterocyclic or heterobicyclic group having a nitrogen heteroatom and a sulfur heteroatom, wherein said heterocyclic or heterobicyclic group can be fused to an optional aromatic group, optional saturated or unsaturated cyclic group, or optional saturated or unsaturated bicyclic group; R 1 is an alkyl, fluoroalkyl, chloroalkyl, aryl, NR b R c wherein R b and R c are each an alkyl group or taken together with the groups to which they are attached form a four to eight membered cyclic group, or R 1 together with R a and the groups to which they are attached form the four to eight membered heterocyclic or heterobicyclic group that can be fused to the optional aromatic group, optional saturated or unsaturated cyclic group, or optional saturated or unsaturated bicyclic group; and r is equal to 1 when X 1 is a monovalent group or equal to 2 when X 1 is a divalent group; and said compound is unsubstituted or substituted with a halo, alkyl, alkoxy, or combinations thereof; providing a substrate having a complementary functional group capable of reacting with X 1 ; preparing a substrate-attached tethering group by reacting X 1 with the complementary functional group on the substrate resulting in an ionic bond, covalent bond, or combination thereof; and reacting an amine-containing material with a N-sulfonylaminocarbonyl group of the substrate-attached tethering group to form a carbonylimino-containing connector group between the substrate and the amine-containing material.