Patent ID: 8143316

Claim:
A method for treating a peripheral vascular disease in a mammalian subject, which comprises administering an effective amount of an 11-deoxy-prostaglandin compound to the subject in need of treatment of a peripheral vascular disease, wherein the treating comprises the care, relief, attenuation or arrest of progression of the peripheral vascular disease, wherein said 11-deoxy-prostaglandin compound is a compound represented by the following formula (III): wherein L is hydrogen, hydroxy or oxo, wherein the five-membered ring may optionally have at least one double bond; A is —CH 3 , —CH 2 OH, —COCH 2 OH, —COOH or a salt, ether, ester or amide thereof; B is —CH 2 —CH 2 —; Z is wherein R 4 and R 5 are hydrogen or hydroxy, wherein R 4 and R 5 are not hydroxy at the same time; X 1 and X 2 are hydrogen or halogen; R 1 is a saturated or unsaturated bivalent lower or medium aliphatic hydrocarbon; R 2 is a single bond or lower alkylene; and R 3 is lower alkyl.