Patent ID: 7763728

Claim:
A compound of formula I wherein Ra is —C(O)R1, R1 is 1-4C-alkyl, 1-4C-alkyl substituted by Raa, or 2-4C-alkyl substituted by Rab and Rac on different carbon atoms, Rb is -T-Q, T is 1-6C-alkylene or 3-7C-cycloalkylene, Q is substituted by Rba and Rbb and Rbc, and is phenyl, Raa is selected from the group consisting of: 3-7C-cycloalkyl, halogen, trifluoromethyl, cyano, hydroxyl, Har, morpholino, —C(O)R2, —C(O)OR3, —C(O)N(R4)R5, —N(R6)C(O)R7, —OC(O)R8, completely or predominantly fluorine-substituted 1-4C-alkoxy, and —OR9, wherein said Har is optionally substituted by one or two substituents independently selected from R10, R2, R3, R4, R5, R6, R7 and R8 are the same or different and are independently selected from the group consisting of: hydrogen and 1-4C-alkyl, R9 is selected from the group consisting of: 1-4C-alkyl, 3-7C-cycloalkyl, 3-7C-cycloalkyl-1-4C-alkyl, hydroxy-2-4C-alkyl, 1-4C-alkoxy-2-4C-alkyl, phenyl-1-4C-alkyl, pyridyl-1-4C-alkyl, and (1-4C-alkoxy-2-4C-alkoxy)-2-4C-alkyl, Har is bonded via a ring carbon or a ring nitrogen atom, and is a 5-membered monocyclic unsaturated, aromatic heteroaryl ring comprising at least one heteroatom independently selected from the group consisting of nitrogen, oxygen and sulphur, or Har is bonded via a ring carbon atom, and is a 6-membered monocyclic unsaturated, aromatic heteroaryl ring comprising one or two nitrogen atoms, or Har is bonded via a ring carbon or a ring nitrogen atom, and is a 9- or 10-membered fused bicyclic unsaturated, aromatic heteroaryl ring comprising one to three heteroatoms independently selected from the group consisting of nitrogen, oxygen and sulphur, each R10 is the same or different and is each independently selected from the group consisting of: 1-4C-alkyl, halogen and 1-4C-alkoxy, Rab is hydroxyl, Rac is hydroxyl, or Rab and Rae bonded to adjacent carbon atoms form together an 1-2C-alkylenedioxy bridge which is optionally substituted by one or two substituents independently selected from the group consisting of fluorine and methyl, or Rab and Rac bonded to carbon atoms two bonds distant from each other form together a methylenedioxy bridge which is optionally substituted by one or two substituents independently selected from the group consisting of fluorine and methyl, Rba is selected from the group consisting of: 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkyl-1-4C-alkoxy, 1-4C-alkoxy-2-4C-alkoxy, phenyl-1-4C-alkoxy, cyano-1-4C-alkoxy, 3-6C-alkinyloxy, nitro, and completely and predominantly fluorine-substituted 1-4C-alkoxy, Rbb is selected from the group consisting of: hydrogen, 1-4C-alkyl, halogen, trifluoromethyl, and 1-4C-alkoxy, Rbc is selected from the group consisting of: hydrogen, 1-4C-alkyl, halogen, trifluoromethyl, and 1-4C-alkoxy, or Rbb and Rbc bounded in ortho position to each other form together an 1-2C-alkylenedioxy bridge, or a completely or partially fluorine-substituted 1-2C-alkylenedioxy bridge, or a salt thereof.