Patent ID: 6852727

Claim:
A compound of fomula I: wherein one of the bond is a double bond, and the other is a single bond; Q is N or C; R 1 is attached to the nitrogen atom having the available valence, and is selected om hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 3-6 cycloalkyl, aryl-C 1-3 alkyl, and aryl wherein said akyl, alkenyl, cycloalkyl, and aryl are optionally substituted with one to three groups independently selected from X; R 2 is a group selected from R 1 ; R 3 , R 4 , R 6 and R 7 are independently selected from hydrogen, X, C 2-6 alkenyl and C 3-6 cycloalkyl wherein said alkenyl and cycloalkyl are optionally substituted with one to three groups independently selected from X; R 5 is selected from hydrogen, C 1-6 alkyl, C 2-6 alkenyl, Cy, and Cy-C 1-3 alkyl, wherein said alkyl, alkenyl, and Cy are optionally substituted with one to three groups independently selected from X; Cy is selected from cycloalkyl, heterocyclyl, aryl, and heteroaryl; X is selected from: halo, CN, OR a , C 1-6 perfluoroalkyl, C(O)R a , C(O)OR a , C(O)NR b R c , NR b R c , NHR b NHR b , NHC(O)R a , NHC(O)OR a , phenyl wherein phenyl is optionally substituted with one to three groups independently selected from R x , C 1-6 alkyl optionally substituted with OH, C 3-7 cycloalkyl, phenyl, or heterocyclyl, wherein phenyl is optionally substituted with one to three groups independently selected from R x , and wherein said heterocyclyl is optionally substituted with one to three groups independently selected from R y , heterocyclyl wherein said heterocyclyl is optionally substituted with one to three groups independently selected from R y , S(O) n R a , wherein n is 0, 1 or 2 and SO 2 NHR a ; R a , R b and R c are independently selected from hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, Cy and Cy-C 1-3 alkyl, wherein Cy is optionally substituted with one to three groups selected from R y ; or R b and R c together with the atom(s) to which they are attached form a heterocyclic ring of 4 to 7 members containing 0-2 additional heteroatoms independently selected from oxygen, sulfur and N—R e ; R e is selected from hydrogen, C 1-6 alkyl, Cy and Cy-C 1-3 alkyl; R x is selected from halo, phenyl, CN, NO 2 , OH, OC 1-6 alkyl, C 1-6 alkyl, NH 2 , C 1-6 alkyl, N(C 1-6 alkyl) 2 , C(O)C 1-6 alkyl, C(O)OC 1-6 alkyl, C(O)NHC 1-6 alkyl, C(O)N(C 1-6 alkyl) 2 , NHC(O)C 1-6 alkyl; R y is a group selected from R x , oxo, C 1-6 alkyl substituted with C 3-7 cycloalkyl and C(O)OCH 2 -phenyl; or a pharmaceutically acceptable salt thereof.