Patent ID: 8580768

Claim:
A compound selected from the compounds 2, 4-6, 8-17, 19, or 21-29: Ex. # Q Y″ X″ X 2 CH(CH 2 OH)CONH 2 4-Cl H Cl 4 CH[CH(CH 3 ) 2 ]CONH 2 3-CONH 2 H Cl 5 CH[CH(CH 3 ) 2 ]CONH 2 3-CN H Cl 6 CH 2 C(NOH)NH 2 4-Cl H Cl 8 CH 2 CH 2 C(NOH)NH 2 4-Cl H Cl 9 CH[CH(CH 3 ) 2 ]CONH 2 3-C(NH)NH 2 H Cl 10 C[(CH 2 ) 3 ]CONH 2 3-OCH 3 H Cl 11 CH(CHOHCH 3 )CONH— 4-Cl H Cl CH(CH 2 OH)CONH 2 12 CH(CHOHCH 3 )CONH 2 3-CN H Cl 13 CH(CHOHCH 3 )CONH 2 3-C(NH)NH 2 H Cl 14 CH 2 CH 2 SO 2 NH 2 3-OCH 3 H Cl 15 CH 2 CH 2 SO 2 NH 2 3-CN H Cl 16 CHCH 3 CONH 2 3-CN H Cl 17 C[(CH 2 ) 3 ]CONH 2 3-CN H Cl 19 CH[CH(CH 2 ) 2 ]CONH 2 4-Cl H Cl 21 CH[CH(CH 2 ) 2 ]CONH 2 3-OMe H Cl 22 CH[CH(CH 2 ) 3 ]CONH 2 3-CN H Cl 23 CH 2 CONHCH 2 CH 2 SO 2 NH 2 4-Cl H Cl 24 CH 2 CH═CHCO 2 CH 3 4-Cl H Cl 25 CH(CHOHCH 3 )CONHCH 2 — 4-Cl H Cl CH 2 SO 2 NH 2 26 CH(CH 2 OH)—CONHCH 2 — 4-Cl H Cl CH 2 SO 2 NH 2 27 4-Cl H Cl 28 CHCH 3 PO(OEt) 2 4-Cl H Cl 29 CH(C 6 H 5 )CONH 2 4-Cl H Cl or a stereoisomer or a pharmaceutically acceptable salt thereof.