Patent ID: 7947850

Claim:
A process for preparing a compound of Formula II, comprising the steps of: (a) reacting a compound of Formula III with sodium borohydride in an aqueous basic solution, wherein R is alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, heteroaralkyl, or heteroaryl, with or without substitution; A is alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, heteroaralkyl, heteroaryl, —CO 2 R 4 , or —(CH 2 ) n OR 5 , with or without substitution; or A is —CO 2 H, CHO, or CN; R 4 is alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, heteroaralkyl, or heteroaryl, with or without substitution; R 5 is H, alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, heteroaralkyl, heteroaryl, or Si(R 6 ) 3 , with or without substitution; R 6 is alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, heteroaralkyl, heteroaryl, or OR 7 , with or without substitution; R 7 is alkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, heteroaralkyl, heteroaryl, with or without substitution; and n is an integer from 1 to 5 (b) adding an aqueous acid solution to quench the reaction; and (c) filtering the reaction product to obtain a solid compound of Formula II.