Patent ID: 8133910

Claim:
A compound of the Formula (I), wherein A represents *—CO—CH 2 CH 2 —, *—CO—CH═CH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I); R 1 represents C 2-5 -alkyl; R 2 represents hydrogen, methyl or ethyl; R 3 represents hydrogen; R 4 represents methyl, ethyl, or methoxy; R 5 represents —CH 2 —(CH 2 ) n —NHSO 2 R 51 , —(CH 2 ) n CH(OH)—CH 2 —NHSO 2 R 51 , —CH 2 —(CH 2 ) n —NHCOR 52 , —(CH 2 ) n CH(OH)—CH 2 —NHCOR 52 , —CH 2 —(CH 2 ) n —CONR 53 R 54 , —CO—NHR 53 , 1-(3-carboxy-azetidinyl)-2-acetyl, 1-(2-carboxy-pyrrolidinyl)-2-acetyl, 1-(3-carboxy-pyrrolidinyl)-2-acetyl, 1-(3-carboxy-azetidinyl)-3-propionyl, 1-(2-carboxy-pyrrolidinyl)-3-propionyl, 1-(3-carboxy-pyrrolidinyl)-3-propionyl, hydroxy, hydroxy-C 2-5 -alkoxy, di-(hydroxy-C 1-4 -alkyl)-C 1-4 -alkoxy, 2,3-dihydroxypropoxy, 2-hydroxy-3-methoxy-propoxy, —OCH 2 —(CH 2 ) m —NHSO 2 R 51 , —OCH 2 —CH(OH)—CH 2 —NHSO 2 R 51 , —OCH 2 —(CH 2 ) m —NHCOR 52 , or —OCH 2 —CH(OH)—CH 2 —NHCOR 52 ; R 51 represents C 1-3 -alkyl, methylamino, ethylamino, or dimethylamino; R 52 represents hydroxymethyl, 2-hydroxyethyl, 2-hydroxy-1-hydroxymethyl-ethyl, or 2,3-dihydroxypropyl; R 53 represents hydrogen, C 1-3 -alkyl, 2-hydroxyethyl, 2-hydroxy-1-hydroxymethyl-ethyl, 2,3-dihydroxypropyl, carboxymethyl, 1-(C 1-5 -alkylcarboxy)methyl, 2-carboxyethyl, or 2-(C 1-5 -alkylcarboxy)ethyl; R 54 represents hydrogen, or methyl; m represents the integer 1 or 2; n represents 0, 1, or 2; and R 6 represents methyl, ethyl or halogen; in free or salt form.