Patent ID: 7595321

Claim:
A compound of the following formula wherein: Z is N; Y is CONR 5 , NR 5 CO, SO 2 NR 5 , NR 5 SO 2 , CH 2 NR 5 , NR 5 CONR 5 , CH 2 CO, CO or CH 2 O; X is N; P is phenyl; Q is C 1-6 alkyl; R is C 0-6 alkyl(SO 2 )NR 1 R 2 ; R 1 and R 2 together form a 1-pyrrolidinyl or 1-piperazinyl moiety, wherein said 1-pyrrolidinyl or 1-piperazinyl moiety may be optionally substituted by A; R 4 is independently selected from CN, OR 6 , CONR 6 R 7 , NR 6 COR 7 , (SO)NR 6 R 7 , SO 2 R 6 , phenyl, 1-imidazolyl, 1-imidazolidinyl, 4-morpholinyl, 1-oxopyrrolidinyl, 1-piperazinyl, 1-pyrrolinyl, 2-thienyl moiety, wherein said phenyl ring or 1-imidazolyl, 1-imidazolidinyl, 4-morpholinyl, 1-oxopyrrolidinyl, 1-piperazinyl, 1-pyrrolinyl, 2-thienyl moiety may be optionally be substituted with A; n is 1; R 5 is hydrogen or C 1-6 alkyl; R 6 and R 7 are independently selected from hydrogen, or C 1-6 alkyl A is oxo (═O), nitro, OR 6 or C 1-6 alkyl; as a free base or a pharmaceutically acceptable thereof.