Patent ID: 7265122

Claim:
A compound of the formula wherein Ar is selected from the group consisting of aryl, heteroaryl, benzoheteroaryl, pyridone, pyridazinone, and pyrimidone; n is 1–6; R 1 and R 2 along with N form a pyrrolidine, piperadine, piperazine, morpholine, benzopyrrolidine, benzopiperadine or benzopiperazine ring; R 3 is H, alkyl or aralkyl; X is C or N; Y is N; R 4 is selected from the group consisting of alkyl, aralkyl, aryl, heteroaryl, benzoheteroaryl, hydroxyl, halo, haloalkyl, alkoxy, aminocarbonyl and aminosulfonyl; or R 5 and R 6 together form a 5–6 membered aromatic ring or a 5–7 membered aliphatic ring; L 1 is selected from the group consisting of, O, NR 7 , and SO 2 ; L 2 and L 3 are a single bond; and R 7 –R 14 are independently selected from the group consisting of H, alkyl, aryl and aralkyl or R 8 and CO and Ar can form pyridone, pyridazinone, and pyrimidone, or a pharmaceutically acceptable salt thereof.