Patent ID: 8461104

Claim:
A method of treating a mammal having an injury, wherein said method comprises the steps of: a) applying a cationic polypeptide to said injury, the cationic polypeptide consisting of amino acid residues R, H, K or a combination thereof; b) applying an anionic polypeptide to said injury, the anionic polypeptide consisting of amino acid residues D, E, or a combination thereof; c) applying a pharmaceutically acceptable carrier to said injury; and d) forming a biodegradable barrier network at the site of said injury, wherein the cationic polypeptide interacts with the anionic polypeptide to form a biodegradable barrier network at the site of said injury that reduces adhesion between tissues; wherein said cationic polypeptide is added separately from said anionic polypeptide.