Patent ID: 8193372

Claim:
A compound of Formula I: or a single enantiomer, a mixture of an enantiomeric pair, an individual diastereomer, a mixture of diastereomers, or a tautomeric form thereof; or a pharmaceutically acceptable salt or an isotopically enriched form thereof; wherein each of R 1 and R 2 is independently —OR 6 , alkyl, alkenyl, alkynyl, aryl, aralkyl, alkaryl, cycloalkyl, heterocyclyl or heteroaryl; R 3 is —C(O)R 7 , —C(O)OR 8 , —C(O)NR 9 R 10 , —C(═NR 11 )R 12 , —P(O)(OR 6 ) 2 or —C(O)NHSO 2 R 21 ; X is CR 4 ; each of R 4 and R 5 is independently H, halogen, cyano, azido, alkyl, alkenyl, alkynyl, aryl, aralkyl, alkaryl, cycloalkyl, heterocyclyl, heteroaryl, —OR 6 , —C(O)R 7 , —C(O)OR 8 , —C(O)NR 9 R 10 , —C(═NR 11 )R 12 , —NHSO 2 R 13 , —NR 14 R 15 , —SO 3 R 17 or —SO 2 R 18 , or R 4 and R 5 together with the two carbon atoms to which they are attached form a ring; L is NR 16 ; and each of R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , and R 21 is independently hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, alkyl-cycloalkylene or cycloalkyl-alkylene, wherein each alkyl, aryl, arylalkyl, alkaryl, heteroaryl, alkenyl, alkynyl, cycloalkyl, heterocyclyl or alkyl-cycloalkyl is optionally substituted.