Patent ID: 8202999

Claim:
A compound represented by formula (I): or a pharmaceutically acceptable salt thereof, wherein: L is —NR—C(O)—; X 1 and X 3 are each CH; X 2 is CH; each Z is independently selected from the group consisting of a lower alkyl, a lower haloalkyl, a halo, a lower alkoxy, a lower alkyl sulfanyl, cyano, nitro, or lower haloalkoxy; R, for each occurrence is independently selected from —H, an alkyl, —C(O)R 5 , or —C(O)OR 5 ; R 1 and R 2 are each, independently, a halo, a lower alkyl, a lower alkoxy, or a haloalkoxy; R 3 is an alkyl, a haloalkyl, a halo, a haloalkoxy, —OR 5 , —SR 5 , or —NR 6 R 7 ; R 18 is an optionally substituted pyridinyl, an optionally substituted oxazolyl, an optionally substituted isoxazolyl, an optionally substituted pyrazolyl, an optionally substituted thiazolyl, an optionally substituted pyrrolyl, an optionally substituted morpholinyl, an optionally substituted furanyl, an optionally substituted thienyl, an optionally substituted thiadiazolyl, an optionally substituted triazolyl, an optionally substituted oxadiazolyl, an optionally substituted imidazolyl, or an optionally substituted tetrazolyl; R 5 , for each occurrence, is independently, H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl; R 6 and R 7 , for each occurrence are, independently, H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl; or R 6 and R 7 taken together with the nitrogen to which they are attached are an optionally substituted heterocyclyl or optionally substituted heteroaryl; and n is zero or an integer from 1 to 4.