Patent ID: 8084258

Claim:
A kit comprising in one or more containers (a) an agonist of Notch pathway function selected from the group consisting of a Notch protein or a fragment of a Notch protein, a Delta protein or a fragment of a Delta protein, a Serrate protein or a fragment of a Serrate protein, a Jagged protein or a fragment of a Jagged protein, a Suppressor of Hairless protein or a fragment of a Suppressor of Hairless protein, a nucleic acid encoding a Notch protein or a fragment of a Notch protein, a nucleic acid encoding a Delta protein or a fragment of a Delta protein, a nucleic acid encoding a Serrate protein or a fragment of a Serrate protein, a nucleic acid encoding a Jagged protein or a fragment of a Jagged protein, a nucleic acid encoding a Suppressor of Hairless protein or a fragment of a Suppressor of Hairless protein, and a dominant-active Notch mutant; and (b) an agonist of a cell fate control gene pathway function, wherein the cell fate control gene is selected from the group consisting of a Pax gene, a HOX gene, a DLX gene, a Vestigial gene, a PBC gene, a MEINOX gene, a bHLH gene, a LIM homeobox gene, a MSX gene, a POU gene, a PTX gene, a NKX gene, a MADS box gene, a SOX gene, a T-box gene, a WNT gene, a BMP/TGF-β superfamily gene, and a hedgehog gene, and wherein the agonist of cell fate control gene pathway function is selected from the group consisting of a Pax protein, a HOX protein, a DLX protein, a Vestigial protein, a PBC protein, a MEINOX protein, a bHLH protein, a LIM homeobox protein, a MSX protein, a POU protein, a PTX protein, a NKX protein, a MADS box protein, a SOX protein, a T-box protein, a WNT protein, a BMP/TGF-β superfamily protein, a hedgehog protein, a nucleic acid encoding a Pax protein, a nucleic acid encoding a HOX protein, a nucleic acid encoding a DLX protein, a nucleic acid encoding a Vestigial protein, a nucleic acid encoding a PBC protein, a nucleic acid encoding a MEINOX protein, a nucleic acid encoding a bHLH protein, a nucleic acid encoding a LIM homeobox protein, a nucleic acid encoding a MSX protein, a nucleic acid encoding a POU protein, a nucleic acid encoding a PTX protein, a nucleic acid encoding a NKX protein, a nucleic acid encoding a MADS box protein, a nucleic acid encoding a SOX protein, a nucleic acid encoding a T-box protein, a nucleic acid encoding a WNT protein, a nucleic acid encoding a BMP/TGF-β superfamily protein, and a nucleic acid encoding a hedgehog protein.