Patent ID: 8172395

Claim:
A contact lens comprising a core material which is a silicone-containing hydrogel material and an antimicrobial LbL coating that is not covalently attached to the core material, wherein the antimicrobial LbL coating includes: (a) a polyelectrolyte LbL coating and an peptide layer of one or more antimicrobial peptides, wherein the polyelectrolyte LbL coating is composed of (i) at least one layer of a first polyionic material, or (ii) at least one layer of the first polyionic material and at least one layer of a second polyionic material having charges opposite of the charges of the first polyionic material, wherein said first and second polyionic materials, independently of each other, have functional groups which provide reactive sites, and wherein the peptide layer of one or more antimicrobial peptides are covalently attached to the LbL coating through the reactive sites (b) wherein the antimicrobial LbL coating imparts to the core material an increased surface hydrophilicity.