Patent ID: 8110549

Claim:
An isolated pure α-conotoxin peptide comprising the amino acid sequence of: Gly-Cys-Cys-Ser-His-Xaa 5 -Ala-Cys-Ser-Val-Asn-His-Xaa 5 -Xaa 1 -Leu-Cys (SEQ ID NO:34); wherein Xaa 1 is Glu or γ-carboxy-Glu (Gla) and Xaa 5 is Pro or hydroxy-Pro; wherein the C-terminus contains a hydroxyl group or an amide group; wherein the His residue may be substituted with a halo-His residue; and wherein the Cys residues may be in the D or L configuration or substituted with homocysteine in the D or L configuration.