Patent ID: 7655626

Claim:
A composition comprising an isolated antiangiogenic peptide or a fusion protein comprising a heterologous protein fused to the antiangiogenic peptide, wherein the peptide has antiangiogenic activity and consists of the amino acid sequence: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14, wherein X1 is any amino acid residue compatible with forming a helix; X2 is an amino acid residue of: Leu; X3 is an amino acid residue of: Arg, Ser; X4 is an amino acid residue of: Ile, Leu; X5 is any amino acid residue compatible with forming a helix; X6 is an amino acid residue of: Leu, Val; X7 is an amino acid residue of: Leu, Ser; X8 is any amino acid residue compatible with forming a helix; X9 is any amino acid residue compatible with forming a helix; X10 is an amino acid residue of: Gln, Glu, Arg; X11 is an amino acid residue of: Ser; X12 is an amino acid residue of: Trp; X13 is an amino acid residue of: Leu, Asn; X14 is an amino acid residue of: Glu.