Patent ID: 7495007

Claim:
A compound of the formula wherein X is selected from the group consisting of hydrogen, halogen, cyano, nitro, ethynyl, cyclopropyl, methyl, ethyl, isopropyl, methoxy and vinyl, Y is hydrogen or fluorine, R 4 and R 5 are hydrogen or lower alkyl, one of R 1 and R 8 is selected from the group consisting of lower alkyl, substituted lower alkyl, lower alkenyl, substituted lower alkenyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, cycloalkyl, substituted cycloalkyl, cycloalkenyl, and substituted cycloalkenyl and the other is hydrogen, one of R 6 and R 7 is selected from the group consisting of lower alkyl, substituted lower alkyl, lower alkenyl, substituted lower alkenyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, cycloalkyl, substituted cycloalkyl, cycloalkenyl, and substituted cycloalkenyl and the other is hydrogen, cyano or lower alkyl, R 2 is selected from the group consisting of hydrogen, lower alkyl and substituted lower alkyl, R 3 is selected from the group consisting of oxygen, sulfur and NNH(C═O)OR 9 , R 9 is lower alkyl or substituted lower alkyl, and the pharmaceutically acceptable salts carboxylic acid and esters thereof.