Patent ID: 8691853

Claim:
A method of providing relief from or alleviating symptoms of or delaying the progression of lupus in a patient in need of said provision of relief or alleviation of symptoms or delay of progression, the method comprising administering a therapeutically effective amount of at least one compound having the formula: wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 , independently of one another, are substituents selected from H, C 1 -C 6 alkyl, OH, halogen, C 5 -C 14 aryl, C 6 -C 20 aralkyl, C 1 -C 6 alkylthio, C 1 -C 6 alkoxy, SH, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, CN, NO 2 , carboxy, carbalkoxy, carboxamido, alkylsulfonyl, alkylsulfonyloxy, aminosulfinyl, monoalkylaminosulfinyl, dialkylaminosulfinyl, aminosulfonyl, monoalkylaminosulfonyl, dialkylaminosulfonyl, alkylsulfonylamino, hydroxysulfonyloxy, alkoxysulfonyloxy, alkylsulfonyloxy, hydroxysulfonyl, alkoxysulfonyl, alkylsulfonylalkyl, aminosulfonylalkyl, monoalkylaminosulfonylalkyl, dialkyaminosulfonylalkyl, aminosulfinylalkyl, monoalkylaminosulfinylalkyl, dialkylaminosulfinylalkyl, said alkyl, alkenyl, alkynyl or cycloalkyl substituent being optionally substituted by at least one halogen, OH, SH, NH 2 , C 1 -C 4 monoalkylamino, C 1 -C 4 dialkylamino, COOH, CN, NO 2 , C 1 -C 4 alkyl or C 1 -C 4 alkoxy group, said aryl and aralkyl substituent being optionally substituted by at least one halogen, OH, SH, NH 2 , C 1 -C 4 monoalkylamino, C 1 -C 4 dialkylamino, COOH, CN, NO 2 , C 1 -C 4 alkyl or C 1 -C 4 alkoxy group; R a , R b and R c , independently of one another, represent substituents selected from H, C 1 -C 4 alkyl, phenyl or phenyl C 1 -C 4 alkyl, said alkyl substituent, said phenyl substituent and said phenyl C 1 -C 4 alkyl substituent being optionally substituted by at least one halogen, OH, SH, NH 2 , C 1 -C 4 alkylmethylamino, C 1 -C 4 dialkylamino, COOH, CN, NO 2 , C 1 -C 4 alkyl or C 1 -C 4 alkoxy group; m, n and k are independent integers from 0-4, except that m+n≠0; and the pharmaceutically acceptable salts of said compound.