Patent ID: 7557068

Claim:
An in vitro method for synthesizing a templated molecule comprising a plurality of functional groups, the method comprising the steps of i) providing at least one template comprising a sequence of n codons, wherein each codon comprises at least one base capable of recognizing a predetermined complementary anti-codon, and wherein n is an integer of more than 1, ii) providing a plurality of transfer units, wherein each transfer unit comprises a) at least one anti-codon comprising at least one base capable of recognizing a predetermined codon of the at least one template, b) at least one reactive unit comprising at least one functional group and at least one reactive group, and c) at least one linker separating the at least one reactive unit from the at least one anti-codon, iii) contacting the at least one template with the plurality of transfer units, and iv) obtaining a templated molecule comprising covalently linked, functional groups by linking, by means of a reaction involving reactive groups, a functional group of at least one reactive unit of at least one transfer unit to a functional group of a reactive unit of at least one other transfer unit, wherein the templated molecule is linked by means of a covalent linker to the template that templated the synthesis of the templated molecule, and wherein the synthesis of the templated molecule does not involve ribosome mediated translation of an mRNA.