Patent ID: 8652500

Claim:
A method for preparing a mixture of bioresorbable particulate matter, comprising: (a) providing a first sheet of bioresorbable material comprising a native extracellular matrix comprising epithelial basement membrane and tunica propria and having a first density and a first rate of resorption, and, milling said first sheet into a first plurality of bioresorbable particles; (b) providing a second sheet of a bioresorbable material comprising another extracellular matrix different than the extracellular matrix material of the first sheet and having a second density and a second rate of resorption, and, milling said second sheet into a second plurality of bioresorbable particles; (c) providing a predetermined quantity of said first plurality of bioresorbable particles and a predetermined quantity of said second plurality of bioresorbable particles; and (d) mixing said predetermined quantity of said first plurality of bioresorbable particles with a predetermined quantity of said second plurality of bioresorbable particles, wherein the second density is 150%-500% of the first density.