Patent ID: 7825271

Claim:
A compound having the formula: wherein X, if present, is R 1 , OR 1 , or SR 1 ; wherein R 1 is (i) hydrogen; (ii) alkyl of 1 to 8 carbon atoms, inclusive, which may be straight chain or branched; (iii) cycloalkyl of 3 to 10 carbon atoms, inclusive; (iv) aralkyl of 7 to 12 carbon atoms; (v) phenyl; (vi) substituted phenyl wherein Z i , Z iii , and Z v are each independently selected from the group consisting of —NO 2 , —CN, —C(═O)—R 1 , methoxy, hydrogen, and —SO 3 H; wherein Z ii and Z iv are each independently selected from the group consisting of halogen, methyl, hydrogen, and hydroxyl; (vii) detectable label molecule; or (viii) alkenyl of 2 to 8 carbon atoms, inclusive, straight chain or branched; wherein Q 1 is (C═O), SO 2 or (CN); wherein Q 3 is O, S or NH; wherein one of R 2 and R 3 is hydrogen and the other is (a) H; (b) alkyl of 1 to 8 carbon atoms, inclusive, which may be straight chain or branched; (c) cycloalkyl of 3 to 6 carbon atoms, inclusive; (d) alkenyl of 2 to 8 carbon atoms, inclusive, which may be straight chain or branched; or (e) R a Q 2 R b wherein Q 2 is —O— or —S—; wherein R a is alkylene of 0 to 6 carbon atoms, inclusive, which may be straight chain or branched; wherein R b is alkyl of 0 to 8 carbon atoms, inclusive, which may be straight chain or branched; wherein R 4 is (a) H; or (b) alkyl of 1 to 6 carbon atoms, inclusive, which may be straight chain or branched; wherein Y 1 or Y 2 is —OH, methyl, or —SH and wherein the other is (a) H; (b) CH a Z b where a+b=3, a=0 to 3, b=0 to 3, Z is cyano, nitro, or halogen; (c) alkyl of 2 to 4 carbon atoms, inclusive, straight chain or branched; or (d) alkoxy of 1 to 4 carbon atoms, inclusive; or Y 1 and Y 2 taken together are (a) ═N; or (b) ═O; wherein R 5 is (a) alkyl of 1 to 9 carbon atoms which may be straight chain or branched; (b) —(CH 2 ) n —R i wherein n=0 to 4 and R i is (i) cycloalkyl of 3 to 10 carbon atoms, inclusive; (ii) phenyl; or (iii) substituted phenyl wherein Z i , Z iii , and Z v are each independently selected from the group consisting of hydrogen, —NO 2 , —CN, —C(═O)—R 1 , methoxy, and —SO 3 H; wherein Z ii and Z iv are each independently selected from the group consisting of halogen, methyl, hydrogen, and hydroxyl; (c) R a Q a R b wherein Q a =—O— or —S—; wherein R a is alkylene of 0 to 6 carbon atoms, inclusive, which may be straight chain or branched; wherein R b is alkyl of 0 to 8 carbon atoms, inclusive, which may be straight chain or branched; (d) —C(R iii )(R iv )—R i wherein R iii and R iv are selected independently from the group consisting of (i) H; or (ii) CH a Z b where a+b=3, a=0 to 3, b=0 to 3, and wherein any Z is selected from the group consisting of halogen; or (e) haloalkyl of 1 to 8 carbon atoms, inclusive, and 1 to 6 halogen atoms, inclusive, straight chain or branched; and wherein R 6 is (a) H; (b) alkyl from 1 to 4 carbon atoms, inclusive, straight chain or branched; or (c) halogen.