Patent ID: 7022472

Claim:
A method of diagnosing hereditary non-polyposis colorectal cancer in a patient comprising: (a) obtaining a DNA or RNA sample from a patient; and (b) screening the DNA or RNA sample with an oligonucleotide probe to detect a hMLH1 mutant 1, a hMSH2 mutant 1, a hMSH2 mutant 2, or a hMSH2 mutant 3, wherein binding of the oligonucleotide probe to the DNA or RNA sample is indicative of the presence of the hMLH1 mutant 1, the hMSH2 mutant 1, the hMSH2 mutant 2, or the hMSH2 mutant 3 and hereditary non-polyposis colorectal cancer.