Patent ID: 7138376

Claim:
A compound of Formula I: or a pharmaceutically acceptable salt or prodrug thereof, wherein: R 1 is alkyl; a, a phospholipid; an amino acid; a carbohydrate; a peptide; or cholesterol R 2 and R 3 are independently H, mono-phosphate, di-phosphate, tri-phosphate; a stabilized phosphate prodrug; acyl; alkyl; sulfonate ester; a phospholipid; an amino acid; a carbohydrate; a peptide; cholesterol; or other pharmaceutically acceptable leaving group that when administered in vivo provides a compound wherein R 2 and R 3 are independently H or phosphate; Y is hydrogen, bromo, chloro, fluoro, iodo, OR 4 , NR 4 R 5 or SR 4 ; X 1 and X 2 are independently selected from the group consisting of H, alkyl, CO-alkyl, CO-aryl, CO-alkoxyalkyl, chloro, bromo, fluoro, iodo, OR 4 , NR 4 NR 5 or SR 4 ; and R 4 and R 5 are independently hydrogen, acyl, or alkyl.