Patent ID: 8668825

Claim:
Device for extracorporeal blood treatment comprising: a filter having a primary and a secondary chamber separated by a semi-permeable membrane, a withdrawal line connected to the primary chamber of the filter, the withdrawal line operationally associated to a first means for regulating blood flow rate Qb, a return line at the outlet of the primary chamber of the filter, a first pre-infusion line connected to a local anticoagulation substance container and connected to the withdrawal line, and operationally associated to a second means for regulating anticoagulation liquid flow rate Qpre 1 , a first post-infusion line connected to a container of a solution at least partially restoring blood ionic balance for infusing the solution in the blood and operationally associated to a third means for regulating the ionic balance restoring solution flow rate Qpost 1 , an effluent line connected at the outlet of the secondary chamber of filter, connected to a drain pipe and operationally associated to a fourth means for regulating liquid effluent liquid flow rate Qeff, wherein the device includes a CPU including a first module programmed to receive the signal output by at least one of the first, second, third and fourth means for regulating liquid flow rate and second module programmed to control at least the third means for regulating the ionic balance restoring solution flow rate Qpost 1 as a function of the input flow rate equal to and chosen in the group consisting of blood flow rate Qb, plasma water blood flow rate Q pw , plasma flow rate Q p , effluent liquid flow rate Qeff and anticoagulation liquid flow rate Qpre 1 , wherein CPU second module is programmed to control at least the third means for regulating the ionic balance restoring solution flow rate Qpost 1 as a function of the following equation (1): Qpost ⁢ ⁢ 1 = α × Fdilu × K ⁢ ⁢ with ⁢ : ⁢ ⁢ α = constant , ⁢ A = constant , ⁢ Fdilu = Qb ( Qb + Qpre ⁢ ⁢ 1 ) , or ⁢ ⁢ Fdilu = Qpw ( Qpw + Qpre ⁢ ⁢ 1 ) , or ⁢ ⁢ Fdilu = Qp ( Qp + Qpre ⁢ ⁢ 1 ) ⁢ ⁢ K = A × Qeff , ⁢ Qpw ⁢ ⁢ being ⁢ ⁢ the ⁢ ⁢ plasma ⁢ ⁢ water ⁢ ⁢ flow ⁢ ⁢ rate , ⁢ Qp ⁢ ⁢ being ⁢ ⁢ the ⁢ ⁢ plasma ⁢ ⁢ flow ⁢ ⁢ rate , ⁢ Fdilu ⁢ ⁢ being ⁢ ⁢ the ⁢ ⁢ dilution ⁢ ⁢ ratio , ⁢ K ⁢ ⁢ being ⁢ ⁢ a ⁢ ⁢ flow ⁢ ⁢ parameter ⁢ ⁢ comprising ⁢ ⁢ the ⁢ ⁢ product ⁢ ⁢ of ⁢ ⁢ a ⁢ ⁢ constant ⁢ ⁢ and ⁢ ⁢ the ⁢ ⁢ effluent ⁢ ⁢ liquid ⁢ ⁢ flow ⁢ ⁢ rate . ⁢ ( 1 )