Patent ID: 7596407

Claim:
An iontophoretic method for the delivery of at least one compound of the formula wherein R is methyl, ethyl, ethyl substituted with one or more fluorine atoms, or cyclo-(C 3-7 )-alkylmethyl optionally substituted with one or more fluorine atoms, or a benzyl, 2-pyridylmethyl, 3-pyridylmethyl or 4-pyridylmethyl radical optionally substituted with one or more substituents which are the same or different and are independently chosen from halogen, hydroxyl, cyano, amino, mono-C 1-3 -alkylamino, di-C 1-3 -alkylamino, C 1-3 -alkoxy, CF 3 , OCF 3 , SCF 3 , C 1-4 -alkyl, C 1-3 -alkylsulfonyl amino, phenyl, furanyl and thienyl and wherein said substituents phenyl, furanyl and thienyl are optionally substituted with 1-3 moieties which are the same or different and are chosen from hydroxy, halogen, C 1-4 -alkoxy, C 1-4 -alkyl, cyano, aminocarbonyl, mono-C 1-4 -alkylaminocarbonyl and di-C 1-4 -alkylaminocarbonyl; at least one prodrug thereof, at least one pharmaceutically acceptable salt of either of the foregoing, or a mixture of any of the foregoing, wherein the method comprises: (a) applying a transdermal device to the skin of a living body, wherein the transdermal device comprises a reservoir comprising the at least one compound of formula I as set forth above and optionally a pharmaceutically acceptable electrolyte; (b) causing current to flow through the skin so as to iontophoretically deliver to the living body the at least one compound of formula I as set forth above.