Patent ID: 7622270

Claim:
A method of selecting a dopaminergic neuron precursor cell, wherein the method comprises: contacting a cell sample comprising ventral midbrain cells with an antibody that binds to a polypeptide encoded by a polynucleotide comprising a sequence selected from (i) a nucleotide sequence comprising nucleotides 178 to 2280 of SEQ ID NO: 1 or nucleotides 127 to 2079 of SEQ ID NO: 2; (ii) a nucleotide sequence encoding the amino acid sequence of SEQ ID NO: 3 or 4; (iii) a nucleotide encoding residues 18-700 of SEQ ID NO:3 or residues 18-650 of SEQ ID NO:4 (iv) a nucleotide sequence encoding an amino acid sequence which has 80% or more identity with the amino acid sequence of SEQ ID NO: 3 or 4; and or a fragment of said polypeptide comprising at least eight amino acid residues; and isolating the dopaminergic neuron precursor cell, wherein the dopaminergic neuron precursor cell has bound to the antibody.