Patent ID: 8592187

Claim:
A process for producing an L-amino acid, which comprises a) fermenting an isolated coryneform bacterium in a suitable medium, where the bacterium comprises at least one copy of a polynucleotide that encodes a polypeptide having OxyR transcription regulator activity, wherein the polypeptide comprises 1) an amino acid sequence of SEQ ID NO:2, with one of the proteinogenic amino acids except L-alanine being present at position 89, and with L-valine being present at position 244, 2) an amino acid sequence which is at least 97% identical to the amino acid sequence of SEQ ID NO:6, with L-valine being present at position 244, 3) an amino acid sequence selected from the group consisting of i) amino acid sequence of SEQ ID NO:6, and ii) amino acid sequence of SEQ ID NO:6 including one or more conservative amino acid exchange(s), 4) an amino acid sequence of SEQ ID NO:2, with L-valine being present at position 89, and with L-valine being present at position 244, or 5) a combination thereof, and b) accumulating the L-amino acid in the fermentation broth or in the cells of the bacterium.