Patent ID: 7897917

Claim:
A device for generating analyte ions for a mass spectrometer, comprising: a housing having at least one wall defining a chamber and configured to be affixed proximate to a vacuum region orifice of a mass spectrometer; a sample inlet in the at least one wall of the housing and configured for communication with a chromatograph to receive an NSC fluid in which an analyte is dissolved or suspended and to direct the NSC fluid into the chamber to form a sample jet of NSC fluid; an ionization media inlet in the at least one wall of the housing and configured for communication with a source of ionization media, the ionization media inlet configured to direct the ionization media into the chamber in a neutral state to interact with the sample jet of NSC fluid and thereby create analyte ions; and an outlet in the at least one wall of the housing and in communication with the vacuum region orifice to provide the analyte ions to the mass spectrometer.