Patent ID: 7910107

Claim:
A method for increasing muscle mass in a mammal comprising administering a therapeutically effective amount of an antibody selected from the group consisting of: (a) an isolated antibody capable of binding GDF-8 comprising a heavy chain variable region comprising three complementarity determining regions (CDRs) comprising the amino acid sequences of SEQ ID NO: 10, SEQ ID NO: 11, and SEQ ID NO: 12, and a light chain variable region comprising three CDRs comprising the amino acid sequences of SEQ ID NO: 13, SEQ ID NO: 14, and SEQ ID NO: 15; and (b) an isolated antibody capable of binding GDF-8 comprising the amino acid sequences of SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, and SEQ ID NO: 15, thereby increasing muscle mass in the mammal.