Patent ID: 7943325

Claim:
A method of diagnosing an infertility condition in a human female subject in which the condition is pre-eclampsia or intrauterine growth restriction (IUGR), the method comprising (a) detecting pregnancy-related serine protease (PRSP) protein in a test sample taken from said subject at between 8 and 20 weeks into pregnancy; (b) detecting PRSP protein in a control sample from a fertile control human female taken at the same number of weeks into pregnancy in the control as the sample taken from the subject; and (c) comparing the PRSP protein in the test sample with the PRSP protein detected in the control sample, wherein the PRSP protein comprises a sequence selected from the group of the sequences set out in SEQ ID NO: 2, 5, 6 or 8, in which a change in the PRSP protein in the test sample compared to the control sample is indicative of said condition.