Patent ID: 6861446

Claim:
A method of inhibiting tumor growth in a mammal, said method comprising administering a therapeutically effective amount of a composition comprising at least one pharmaceutically acceptable carrier and a taxane having the formula wherein X3 is 2-thienyl, 3-thienyl, 2-furyl, 3-furyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, isopropyl, isobutenyl, cyclopropyl, cyclobutyl or cyclopentyl; X 5 is —COX 10 and X 10 is 2-furyl, 2-thienyl, 3-pyridyl, 4-pyridyl, n-propyl, isobutyl, or butenyl or X 5 is —COOX 10 and X 10 is ethyl, n-propyl, isopropyl or isobutyl; R 2 is benzoyloxy; R 7 is R 7a COO—; R 10 is hydroxy; and R 7a is heterosubstituted methyl.