Patent ID: 6955738

Claim:
A method for the manufacture of a microfluidic device comprising one or more enclosed microchannel structures, each of which comprises a section that is defined between two essentially planar substrates, wherein one surface in either one or both of the substrates comprises microstructures in the form of grooves or projections that match each other so that they together define said section for each of said one or more microchannel structures when the two surfaces are apposed in the microfluidic device, the method comprises the steps of: (i) providing the planar substrates, (ii) placing at least one substrate in a gas plasma reactor, and creating within said plasma reactor a gas plasma containing an organic precursor compound, said organic precursor compound and the conditions in the reactor are selected such that a wettable coat that is also anti-fouling is formed on a selected part of the surface of the substrate, iii) removing the substrate from the plasma reactor, and (iv) adhering the surfaces of the substrates to each other so that said section of each of said microchannel structures is formed between the two surfaces.