Patent ID: 8633303

Claim:
A compound or physiologically acceptable salt thereof, having the formula: wherein: where n=0-2, and R 8 are independently selected where n=2; R 2 = —[C(═O)NH(CH 2 ) n NHC(═O)] m (L) m Z, where n=0-30, m=0-1, L is a linker, and Z is wherein M is H or a pharmaceutically acceptable counterion; —O—C(═O)—X, —NH 2 , —NH—C(═O)—NHX, or —NH—C(═O)—X where n=0-2 and X is independently selected from C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, and any of the above ring compounds may be substituted with one to three independently selected of Cl, F, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, or C 5 -C 14 aryl; or OY where Y is H, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, or C 5 -C 14 aryl; 6′sulfated GlcNAc, 6′carboxylated GlcNAc, 6′sulfated GalNAc, 6′sulfated galactose, 6′carboxylated galactose, where R 9 is aryl, heteroaryl, cyclohexane, t-butane, adamantane, or triazole, and any of R 9 may be substituted with one to three independently selected of Cl, F, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl or OY where Y is H, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl or C 5 -C 14 aryl; or where R 10 is aryl, heteroaryl, where n=0-10, and any one of the above ring compounds may be substituted with one to three independently selected from Cl, F, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl or OY where Y is H, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl or C 2 -C 8 alkynyl; R 5 =H; R 6 =H, fucose, mannose, arabinose, galactose or polyols; R 7 =H, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl or and R 8 =H, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, where n=0-3 and X is independently selected from H, OH, Cl, F, N 3 , NH 2 , C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 5 -C 14 aryl, OC 1 -C 8 alkanyl, OC 2 -C 8 alkenyl, OC 2 -C 8 alkynyl and OC 5 -C 14 aryl, and any of the above ring compounds may be substituted with one to three independently selected from Cl, F, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 5 -C 14 aryl or OY where Y is H, C 1 -C 8 alkanyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, or C 5 -C 14 aryl.