Patent ID: 8318764

Claim:
A compound of Formula I wherein: Q is phenyl or heteroaryl, optionally substituted with one or more Q′; Q′ is halogen, hydroxy, lower alkyl, lower haloalkyl, lower hydroxyalkyl, amino, lower alkoxy, or lower haloalkoxy; Q 1 is O or C(Q 1′ ) 2 ; each Q 1′ is independently H, halogen, hydroxy, lower alkyl, lower haloalkyl, lower hydroxyalkyl, amino, lower alkoxy, or lower haloalkoxy; Q 2 is (C(Q 2′ ) 2 ) n , N(Q 2″ ), or C(Q 2′ ) 2 C(Q 2′ ) 2 ; each Q 2′ is independently H, halogen, hydroxy, lower alkyl, lower haloalkyl, lower hydroxyalkyl, amino, lower alkoxy, or lower haloalkoxy; or Q 2″ and Q 3′ together form a heterocyclic ring; n is 2, 3, 4, or 5; Q 3 is O, N(Q 3′ ), C(Q 3′ ) 2 , carbocyclyl, or heterocyclyl; each Q 3′ is independently H, halogen, hydroxy, lower alkyl, lower haloalkyl, lower hydroxyalkyl, amino, lower alkoxy, phenyl, benzyl, or lower haloalkoxy; or both Q 3′ together form a spirocyclic carbocyclic or heterocyclic ring; and Q 4 is C(═O) or S(═O) 2 ; with the proviso that when Q 2 is N(Q 2″ ), then Q 3 is not N(Q 3′ ); or a pharmaceutically acceptable salt thereof.