Patent ID: 8710057

Claim:
A compound having a structure according to structure (I) below: including stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, where: X is NH, S, O, SO or SO 2 ; R is H, —OH, halo, alkyl, haloalkyl, alkoxy or haloalkoxy; R 1 has the following structure: where R 1 ′ is —CF 3 and m is 1, 2, 3, 4 or 5; and R 2 is —(CH 2 ) n -cyclopropyl, —(CH 2 ) n -cyclopentyl or —(CH 2 ) n -cyclohexyl, where n is 0, 1, 2, 3 or 4, and wherein the —(CH 2 ) n -cyclopropyl, —(CH 2 ) n -cyclopentyl and —(CH 2 ) n -cyclohexyl moieties are each optionally substituted with one or more substituents selected from hydroxyalkyl.