Patent ID: 7276511

Claim:
A benzylamine or its salt represented by formula (1): wherein X 1 represents —N(CH 3 )—, —NH—, or —O—; X 2 represents a single bond, —NH—, an amido bond, an ester bond, —O—, —S—, or —CO—; each of X 3 and X 4 represents a hydrogen atom or a halogen atom; R 1 represents a hydrogen atom; a lower alkyl group; a phenyl group which may be substituted by 1 to 3 halogen atoms or cyano groups; a benzyl group which may be substituted by 1 to 3 lower alkyl groups, cyano groups, halogeno(lower alkyl) groups, or lower alkoxy groups; a benzoyl group which may be substituted by 1 to 3 lower alkyl groups, hydroxyl groups, halogeno(lower alkyl) groups, or lower alkoxy groups; a lower alkanoyl group which may be substituted by 1 to 5 halogen atoms, amino groups, or carbamoyl groups; a hydroxyl group; a carbamoyl group; a lower alkylsulfonyl group; a lower alkoxycarbonyl-lower alkyl group; a thienylcarbonyl group; a pyridylcarbonyl group; a lower alkylcarbonyl group; or a phenoxycarbonyl group; R 2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkylsulfonyl group, a C3-C7 cycloalkyl group, a C6-C14 cycloalkyl-alkyl group, a C6-C14 aryl group, a C6-C14 aryloxy group, a C6-C14 aryloxy-lower alkyl group, C6-C14 arylthio-lower alkyl group, a C7-C16 aralkyl group, a lower alkoxycarbonyl-lower alkyl group, a lower alkoxy-lower alkyl group, an amino-lower alkyl group, a C7-C16 aralkyl group substituted by a C3-C7 cycloalkyl group, a halogeno(lower alkyl)carbonyl group, an indanyl group, a 1,2,3,4-tetrahydronaphthalenyl group, a xanthenyl group, a piperidinyl group, a pyrrolidinyl group, a morpholino group, a tetrahydroisoquinolyl group, an indolyl group, a chromenyl group, an isobenzofuranyl group, a tetrahydropyranyl group, a benzothienyl group, an adamantyl group, an adamantyl(lower alkyl) group, a fluorenyl group, a fluorenyl(lower alkyl) group, a pyridyl(lower alkyl) group, or an amino group which may be substituted by a phenyl group or a lower alkyl group wherein a ring hydrogen of these group may be substituted by 1 to 5 atoms or groups selected from among a halogen atom, a lower alkyl group, a lower alkoxy group, a nitro group, an oxo group, a halogeno(lower alkyl) group, a C6-C14 aryl group, and a lower alkylamino group; when R 3 represents a (lower alkanoyl)amino group, an amino(lower alkanoyl) group, an amino(lower alkanoyl)amino group, a di(lower alkyl)carbamoylamino group, or a C7-C16 aralkyloxy(lower alkyl) group, R 4 represents a hydrogen atom; or R 3 and R 4 may together form —SOCH 2 —, —SO 2 CH 2 —, —NHCOCH 2 —, —CH(OH)CH 2 —, —OCH 2 —, or —C(═NOH)CH 2 —; R 5 represents a hydrogen atom or a lower alkyl group; n 1 is 1 or 2; and n 2 is 0 or 1.