Patent ID: 6972280

Claim:
A method for inducing myelination of a neural cell by a glial cell, said method comprising contacting said glial cell with an amount of a polypeptide which comprises an epidermal growth factor-like domain, wherein said epidermal growth factor-like domain comprises an amino acid sequence which is identical to an amino acid sequence encoded by a GGF/p185 B2 ligand gene, and wherein said amino acid sequence comprises an amino acid sequence encoded by a nucleic acid sequence selected from the group consisting of: SEQ ID NO: 154 (EGFL1); SEQ ID NO: 155 (EGFL2); SEQ ID NO: 156 (EGFL3); SEQ ID NO: 157 (EGFL4); SEQ ID NO: 158 (EFGL5); SEQ ID NO: 159 (EFGL6); and amino acids 53-103 encoded by SEQ ID NO: 150.