Patent ID: 8299242

Claim:
A process for preparing a compound of formula I: comprising: a) contacting an acid solvate of a compound of formula II: with an amide under conditions suitable for forming an amide solvate of the compound of formula II; and b) contacting the amide solvate with an aqueous base comprising sodium ions under conditions suitable for forming the compound of formula I wherein the carboxylic acid is R 1 COOH wherein R 1 is —H or a C 1 -C 4 alkyl optionally substituted with up to three halo; and the amide is R 30 CON(R 2 ) 2 where each R 2 is independently —H or C 1 -C 4 alkyl or both R 2 together with the nitrogen to which they are attached form a 4 to 6 membered aliphatic ring, and R 30 is —H or C 1 -C 4 alkyl; or R 30 and one of the R 2 together with the carbon and nitrogen to which they are attached, respectively, combine to form a 4 to 6-membered aliphatic ring and the other R 2 is independently —H or C 1 -C 4 alkyl.