Patent ID: 8039464

Claim:
A method of reducing pathological damage in a subject suffering from lung cancer, comprising administering to the subject a therapeutically effective amount of a compound of formula I wherein the cyclic groups A and B are independently selected from wherein R3 is halo, C 1 -C 4 -(halo)-alkyl, C 1 -C 4 -(halo)-alkoxy, amino, C 1 -C 4 -alkylamino, or di(C 1 -C 4 -alkyl)amino, m is an integer of 0-2, and W is NR 1 , R1 is hydrogen, Y or COY, R2 is hydrogen or C 1 -C 4 -(halo)-alkyl, and Y is C 1 -C 6 (halo)-alkyl, or C 3 -C 8 cyclo-(halo)-alkyl, wherein the alkyl or cycloalkyl group is optionally substituted with a five- or six-membered ring optionally containing at least one heteroatom selected from N, S and O, wherein the ring is optionally mono- or poly-substituted with halo, C 1 -C 4 -(halo)alkyl, C 1 -C 4 (halo)alkoxy, amino, C 1 -C 4 -alkyl amino, di (C 1 -C 4 -alkyl)amino or Z, wherein Z is a C 2 -C 6 (halo)-alkyl group w-substituted with a group N(R4) 2 , wherein each R4 is independently hydrogen, C 1 -C 8 alkyl, or CO—C 1 -C 8 -alkyl or wherein both R4 together form a five- or six-membered ring optionally containing at least one further heteroatom selected from N, S and O, wherein the ring is optionally mono- or polysubstituted with halo, C 1 -C 4 (halo)-alkyl and C 1 -C 4 (halo)-alkoxy, a salt thereof.