Patent ID: 6943161

Claim:
A compound, or a salt thereof, represented by Formula I, wherein: R 1 is chosen from arylalkyl, fused arylcycloalkyl, cycloalkyl(alkyl), aminocarbonylalkyl, alkoxyalkyl, substituted arylalkyl, heteroaryl other than 2-pyridinyl, heteroarylalkyl, heterocyclylalkyl, and substituted heterocyclylalkyl; R 2 is chosen from wherein R 5 is chosen from H, alkyl and substituted alkyl; R 6 is a direct bond; and R 7 is chosen from heterocyclyl other than 2-pyridinyl and substituted heteroaryl other than 2-pyridinyl; R 3 is chosen from a direct bond, wherein the left hand bond is the point of attachment to the ring and the right hand bond is the point of attachment to R 1 ; R 4 is chosen from H, halogen, alkyl, a saturated cyclic structure of from 1 to 6 carbon atoms containing from 1 to 4 heteroatoms chosen from O, N and S, a bicyclic 9- to 10-membered heteroaryl containing from 1 to 4 heteroatoms chosen from O, N and S, alkylamino, aminocarbonyl, acyl, —C(═NH)NH 2 , C(S)NHR 12 , CHR 13 R 14 , C(O)NHR 15 , C(O)(CH 2 ) 0-2 R 16 , S(O 2 )R 17 , OR 18 , wherein R 10 is chosen from H, OH, alkyl, cycloalkyl and substituted cycloalkyl; R 11 is chosen from H, OH, COOH, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, alkoxy, aminocarbonyl, aminocarbonylalkyl, with the proviso that, when R 3 is a direct bond, R 11 cannot be 2-pyridinyl or substituted 2-pyridinyl; R 12 is chosen from alkyl, cycloalkyl and aryl; R 13 is chosen from H and aryl; R 14 is chosen from aryl, substituted aryl, heteroaryl, substituted alkyl, aryl substituted alkyl and alkoxy substituted alkyl, R 15 is chosen from alkyl, aryl, substituted aryl and substituted alkyl; R 16 is chosen from aryl, substituted aryl, heteroaryl, carboxyl, alkoxy, substituted alkyl, cycloalkyl, substituted cycloalkyl, aminocarbonyl, substituted aminocarbonyl, heterocyclyl and R 17 is chosen from alkyl and dialkylamino; R 18 is chosen from C 1 to C 20 alkyl, substituted C 1 to C 20 alkyl; and Y is chosen from H and lower alkyl.