Patent ID: 7214800

Claim:
A compound chosen from: compounds having the structure wherein: R 1 is chosen from hydrogen, optionally substituted alkyl-, optionally substituted aryl-, optionally substituted aralkyl-, optionally substituted heteroaryl-, and optionally substituted heteroaralkyl-; R 2 and R 2 ′ are independently chosen from hydrogen, optionally substituted alkyl-, optionally substituted aryl-, optionally substituted aralkyl-, optionally substituted heteroaryl-, and optionally substituted heteroaralkyl-; or R 2 and R 2 ′ taken together form an optionally substituted 3- to 7-membered ring; R 5 , R 6 , R 7 and R 8 are independently chosen from hydrogen, optionally substituted alkyl-, optionally substituted alkoxy, halogen, hydroxyl-, nitro, cyano, dialkylamino, alkylsulfonyl-, alkylsulfonamido, alkylthio, carboxyalkyl-, carboxamido, aminocarbonyl-, optionally substituted aryl-, optionally substituted aryloxy, optionally substituted heteroaryl-, and optionally substituted heteroaryloxy; R 9 is chosen from hydrogen, optionally substituted alkyl-, optionally substituted aryl-, optionally substituted aralkyl-, and optionally substituted heteroaryl-; and R 10 , R 10′ , R 11 , and R 11′ are independently hydrogen, optionally substituted alkyl-, optionally substituted aryl-, or optionally substituted aralkyl-, including single stereoisomers and mixtures of stereoisomers; pharmaceutically acceptable salts of a compound of Formula Ia or Ib; pharmaceutically acceptable solvates of a compound of Formula Ia or Ib; and pharmaceutically acceptable solvates of a pharmaceutically acceptable salt of a compound of Formula Ia or Ib.