Patent ID: 8084575

Claim:
Recombinant seven-transmembrane receptor, further defined as a recombinant G protein-coupled receptor, whereby the amino terminus of said recombinant receptor is located on an extracellular side and the carboxy-terminus is located on an intracellular side of a membrane, comprising at least two detectable labels, whereby a first of said at least two detectable labels is, or is located on, the carboxy-terminus and whereby a second of said at least two labels is, or is located on, the first or third intracellular loop; or whereby a first of said at least two labels is, or is located on, the first intracellular loop and a second of at said at least two labels is, or is located on, the third intracellular loop, and further wherein the first and second labels are detectable by resonance energy transfer.