Patent ID: 8907092

Claim:
A compound of formula Va, VIa, VIIa, or XX, wherein X 1 and X 2 are each independently O or S; R 2 is cyclohexyl, phenyl, or piperidinyl; R 3 is H or alkyl; R 3 ′ is H; R 4 and R 4 ′ are independently H or alkyl; R 5 is H or alkyl; G 1 and G 2 are each independently IVb: wherein R 1 is H; R 5 ′ is H or alkyl; R 6 and R 6 ′ are each H; A 1 is a thiazole or thiadiazole optionally substituted with acylamino, or a heterocycle; wherein each heterocycle substitution is optionally substituted with alkyl; X 3 is O or S; and Y is CH 2 ; and M is —C(O)NH(CH 2 ) 7 NHC(O)—, —C(O)NH(CH 2 ) 11 NHC(O)—, —C(O)NH—(CH 2 O) 2 —(CH 2 ) 2 —NHC(O)—, —C(O)NH—CH 2 CH 2 CH 2 —NR y —CH 2 CH 2 CH 2 —NHC(O)—, —C(O)NH—CH 2 —CH(OH)—CH 2 —NHC(O)—, —C(O)NH—CH 2 —C(CH 3 ) 2 —CH 2 —NHC(O)—, or —C(O)NHCH 2 -phenyl-CH 2 —NHC(O)—; wherein R y is methyl, acetyl, or —C(O)—(CH 2 ) 1-6 -(3-(2-amino-2-carboxyethyl)-2,5-dioxopyrrolidin-1-yl); or a pharmaceutically acceptable salt thereof.