Patent ID: 7528134

Claim:
A method of treating sexual dysfunction in a mammal comprising administering to said mammal in need of such treatment a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein A is selected from the group consisting of aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, heterocycle, and heterocyclealkyl; L is selected from the group consisting of —N(R 7 )C(O)—, and —C(O)N(R 7 )—, wherein the left end of said —N(R 7 )C(O)—, or —C(O)N(R 7 )—, is attached to A and the right end is attached to D; D is selected from the group consisting of alkylene, fluoroalkylene, and hydroxyalkylene; Z is selected from the group consisting of C and CR B , wherein R B is hydrogen; R A is selected from the group consisting of hydrogen and alkyl; — is a bond when Z is C and — is absent when Z is CR B ; B is selected from the group consisting of: R 1 , R 2 , R 3 , R 4 and R 5 are each independently selected from the group consisting of hydrogen, alkoxy, alkenyl, alkyl, alkylsulfinyl, alkylsulfonyl, alkylthio, alkynyl, alkoxycarbonyl, alkylcarbonyl, alkylcarbonyloxy, carboxy, cyano, formyl, halogen, haloalkoxy, haloalkyl, hydroxy, hydroxyalkyl, mercapto, nitro, —NZ 1 Z 2 , (NZ 3 Z 4 )carbonyl, and (NZ 3 Z 4 )sulfonyl; Z 1 and Z 2 are each independently selected from the group consisting of hydrogen, alkyl, alkylcarbonyl, alkylsulfonyl, aryl, arylalkyl, arylalkylsulfonyl, arylsulfonyl, and formyl; Z 3 and Z 4 are each independently selected from the group consisting of hydrogen, alkyl, aryl, and arylalkyl; X is selected from the group consisting of N(R 6 ), O and S; Y is selected from the group consisting of C(R 4 ) and N; R 6 is selected from the group consisting of hydrogen and alkyl; and R 7 is selected from the group consisting of hydrogen and alkyl.