Patent ID: 8435527

Claim:
A method of purifying an antibody comprising a) placing a starting material containing said antibody on a protein A affinity chromotography column, b) desorbing said antibody from said column using a buffer solution adjusted to pH 4.0 to 5.0 comprising arginine and/or a derivative thereof, and c) recovering the antibody, wherein said step of recovering the antibody does not induce association or aggregation of the antibody, said antibody is selected from the group consisting of a natural human antibody, a humanized antibody, a human-type antibody, an antibody prepared by genetic recombination and a monoclonal antibody, and said arginine derivative is selected from the group consisting of acetyl arginine, agmatine, L-arginic acid, N-α-butyroyl-L-arginine, and N-α-pyvaloyl arginine.