Patent ID: 7504416

Claim:
A compound of formula (IE) or a pharmaceutically acceptable salt, prodrug or solvate thereof and wherein R 3 , Z, R 9 and R 6 are selected from the following groups: i) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—, the group R 9 —R 6 is —C 2 H 5 ; ii) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—, the group R 9 —R 6 is cyclobutyl; iii) R 3 is H, Z is the group —O—C(CH 3 ) 2 —CONH, the group R 9 —R 6 is CH 3 ; iv) R 3 is H, Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—, the group R 9 —R 6 is CH 3 ; v) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CON(CH 3 )—, the group R 9 —R 6 is —CH 3 ; vi) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—, the group R 9 —R 6 is cyclopropyl; vii) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—CH 2 , the group R 9 —R 6 is cyclopropyl; viii) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—CH 2 , the group R 9 —R 6 is CH 3 ; ix) R 3 is —NHCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—; the group R 9 —R 6 is CH 3 ; x) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —(CH 2 ) 2 —, the group R 9 —R 6 is pyridine; xi) R 3 is —NHCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—, the group R 9 —R 6 is cyclopropyl; xii) R 3 is —OCH 3 , Z is the group —O—C(CH 3 ) 2 —CONH—CH 2 —CONH—(CH 2 ) 2 —N(CH 3 )—, the group R 9 —R 6 is —CH 3 ; and xiii) R 3 is 3-(1-morpholino)propoxy, Z is the group —O—C(CH 3 )—CONH—, the group R 9 —R 6 is —(CH 2 ) 2 OH.