Patent ID: 8008296

Claim:
A compound structurally represented by Formula I or a pharmaceutically acceptable salt thereof, wherein: R1 is independently —N(R2)SO 2 -phenyl (wherein the phenyl is optionally substituted with R4), —N(R2)SO 2 —CH 2 -phenyl (wherein the phenyl is optionally substituted with R4), —SO 2 N(R2)(R3), —SO 2 —N-pyrrolidinyl (wherein the pyrrolidine is optionally substituted with R4), —SO 2 —N-piperidinyl (wherein the piperidine is optionally substituted with R4), —SO 2 —N-morpholinyl, or —X—(CH 2 ) n —R5 (wherein X=—S— and n is 0, 1, 2, 3, or 4); wherein when n is 0 then (CH 2 ) n is a bond; R2 is independently —H or —(C 1 -C 4 ) alkyl(optionally substituted with one to three halogens); R3 is independently —(C 1 -C 6 ) alkyl(optionally substituted with one to three halogens), —(C 2 -C 4 ) alkylene-N-pyrrolidinyl, —(C 2 -C 4 ) alkylene-N-piperidinyl, —(C 2 -C 4 ) alkylene-N-morpholinyl, —(C 1 -C 4 ) allylene-2-pyridinyl, —(C 1 -C 4 ) alkylene-3-pyridinyl, or —(C 1 -C 4 ) alkylene-4-pyridinyl; R4 is independently —CH 3 , —CF 3 , —CN, or —SO 2 CH 3 ; R5 is independently -2-pyridinyl, -3-pyridinyl, -4-pyridinyl, -2-pyrimidinyl, or -4-pyrimidinyl; R6 is independently —H or —(C 1 -C 3 ) alkyl(optionally substituted with one to three halogens); and R7 is independently —H or —(C 1 -C 3 ) alkyl (optionally substituted with one to three halogens).