Patent ID: 8211467

Claim:
An implantable osmotic drug delivery device, comprising: a reservoir containing a stable, nonaqueous suspension formulation, the suspension formulation comprising: particles comprising an active agent, a sugar, methionine, and a buffer, wherein the active agent comprises a peptide, polypeptide, or protein; and a nonaqueous, single-phase vehicle consisting essentially of about 40% to 60% (w/w) polyvinylpyrrolidone and about 40% to 60% (w/w) benzyl benzoate; a piston within the reservoir, the piston separating the suspension formulation from an osmotic engine; a semipermeable membrane at a first end of the reservoir adjacent the osmotic engine; and a diffusion moderator at a second end of the reservoir adjacent the suspension formulation, the diffusion moderator defining a channel.