Patent ID: 8305583

Claim:
A localized surface plasmon resonance sensing system, comprising: a light source providing an incident light; an optical fiber coupling the incident light, wherein there is not a polarizer or a microscope objective between the light source and the optical fiber; a plurality of noble metal nano-particles being disposed on a surface of the optical fiber in an unclad region to form a noble metal nano-particle submonolayer, the noble metal nano-particles being substantially separated from each adjacent noble metal nano-particles such that the conductivity of the noble metal nano-particle submonolayer is smaller than that of a metal film, and the conductivity of the noble metal nano-particle submonolayer being smaller than 2×10 3 Ω −1 m −1 . a micro-fluidic module accommodating the optical fiber and a sample, and the sample being driven to contact with the noble metal nano-particles; and at least one photo detector detecting a light intensity of an emergent light from the optical fiber without using any light collecting device or polarizer or microscope objective or spectral filter to aid light collection, wherein the emergent light is a transmitted light, a reflected light, or a leaked light from the unclad region and the emergent light is not a fluorescent light, and the photo detector directly detects the light intensity of the emergent light; wherein when the incident light interacts with the noble metal nano-particles, a signal derived from localized surface plasmon resonance in the form of attenuated light or elastic scattered light is outputted through the photo detector.