Patent ID: 7879830

Claim:
A method for self-administering bioidentical hormone replacement therapy for women, comprising the steps of: (a) Presenting a first composition comprising bioidentical estradiol in a pharmacologically acceptable vehicle operable for transdermal delivery of the estradiol by topical administration of the first composition, and a second composition comprising bioidentical progesterone in a pharmacologically acceptable vehicle operable for transdermal delivery of the progesterone by topical administration of the second composition, said first and second compositions being housed in respective first and second dispensers; then (b) Applying said first composition to the woman's skin twice daily over a twenty eight day period in a quantity sufficient to replicate the temporal variations in the serum concentration of said estradiol in the woman in accordance with the estradiol curve beginning at cycle day 1 of, wherein the first composition is administered to the skin in accordance with the following schedule: 4 mg estradiol twice daily on days 1-5; 6 mg estradiol twice daily on days 6-8; 7 mg estradiol twice daily on days 9-11; 8 mg estradiol twice daily on day 12; 2 mg estradiol twice daily on days 13-14; 3 mg estradiol twice daily on days 15-17; and approximately 4 mg estradiol twice daily on days 18-28; and (c) Applying said second composition to the woman's skin twice daily from the luteal phase to day twenty eight in a quantity sufficient to replicate the temporal variations in the serum concentration of said progesterone in the woman in accordance with the progesterone curve beginning at cycle day 14 of, wherein the second composition is administered to the skin in accordance with the following schedule: 100 mg progesterone twice daily on days 14-15; 200 mg progesterone twice daily on days 16-17; 250 mg progesterone twice daily on days 18-19; 300 mg progesterone twice daily on day 20; 350 mg progesterone twice daily on day 21; 300 mg progesterone twice daily on day 22; 250 mg progesterone twice daily on days 23-24; 200 mg progesterone twice daily on days 25-26; and 100 mg progesterone twice daily on days 27-28.