Patent ID: 8492515

Claim:
An isolated and purified compound of the formula (SEQ ID NO: 6) X 1 -X 2 -Pro-X 3 -X 4 -Pro-Arg-Pro-Tyr-Leu-Pro-X 5 -Pro- Arg-Pro-Pro-Arg-Pro-Y wherein; (a) X 1 is selected from the group consisting of: (i) a natural or non-natural amino acid having a free amino group, and (ii) 1-amino-cyclohexyl carboxylic acid, (b) X 2 is Arg or N-methyl-Arg, (c) X 3 is Asp or Glu, (d) X 4 is Arg or Lys, (e) X 5 is Arg or Lys, and (f) Y is Arg, Arg-NH 2 , N-methyl-Arg, N-methyl-Arg-NH 2 , Val-Arg, Val-Arg-NH 2 , Val-(N-methyl-Arg), or Val-(N-methyl)-Arg-NH 2 , or a salt thereof.