Patent ID: 8258154

Claim:
A compound of structural Formula V or a salt thereof, wherein: R 1 and R 2 are independently selected from the group consisting of —(CH 2 ) s G 1 G 2 G 3 , acyl, acylalkyl, carboxyalkyl, cyanoalkyl, alkoxy, alkoxyalkyl, amidoalkyl, amino, alkyl, alkylalkoxy, aminoalkyl, alkenyl, alkynyl, carboxyl, carboxyalkyl, ether, heteroalkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heterocycloalkylalkyl, aralkyl, aryl, guanidine, heteroaryl, heteroaralkyl, and hydroxyalkyl, any of which may be optionally substituted; s is 1-8; G 1 is selected from the group consisting of alkoxy, amino, amido, carbonyl, hydroxy, ether, an amino acid, and null; G 2 is selected from the group consisting of alkyl, alkoxy, amino, aryl, halo, haloalkyl, heterocycloalkyl, heteroaryl, carboxylalkylamino, guanidine, an amino acid, and null, any of which may be optionally substituted; G 3 is selected from the group consisting of alkyl, alkoxy, amino, hydroxy, ether, carboxyl, hydroxamic acid, an amino acid, phosphonate, phosphoamide, and null, any of which may be optionally substituted; R 5 is selected from the group consisting of —(CR 8 R 9 ) m W(CR 10 R 11 ) n — and —(CR 12 R 13 ) p —; W is selected from the group consisting of O, N(R 7 ), C(O)N(R 7 ), and SO q ; m, n, and q are independently 0, 1 or 2; p is 1 or 2; R 6 is selected from the group consisting of carboxyl, alkylcarboxy, amido, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, alkyl, heteroalkyl, acyl, and hydroxamic acid, any of which may be optionally substituted; R 7 and R 14 are independently selected from the group consisting of hydrogen, halogen, hydroxyl, lower alkyl, hydroxyalkyl, haloalkyl, and aminoalkyl; R 8 , R 9 , R 10 , R 11 , R 12 and R 13 are independently selected from the group consisting of hydrogen and optionally substituted lower alkyl; and R 19 is selected from the group consisting of hydrogen, halogen, lower alkyl and haloalkyl.