Patent ID: 8010297

Claim:
An apparatus for analysis of a decoy protein to determine whether a decoy protein has a structure of a native globular protein, the apparatus comprising: a memory; and at least one processor operatively coupled to the memory and configured to: determine a normalized second-order hydrophobic moment profile for the decoy protein; use the normalized second-order hydrophobic moment profile to determine a scoring function for analysis of the decoy protein use the scoring function to generate a score for the decoy protein, wherein the scoring function comprises S H = ∫ 0 1 ⁢  H ~ 2  ⁢ ⁢ ⅆ s , wherein the score comprises an integral of an area under the normalized second-order hydrophobic moment profile of the decoy protein, and wherein the score measures a prominence of a hydrophobic core and a prominence of a hydrophilic exterior of the decoy protein; and use the score of the decoy protein to determine whether the decoy protein has a structure of a native globular protein.