Patent ID: 7211108

Claim:
A flexible vascular graft for connecting to a blood vessel, said vascular graft comprising a flexible wall that forms a passageway for blood flow through the vascular graft, a first drug layer at least partially coated on an inner surface of said flexible wall and an inner layer, said inner layer formed of a porous material designed to promote endothelialization, said first drug layer including at least one drug and a flexible and substantially biologically inert amphiphilic block copolymer, said amphiphilic block copolymer having a structure that controllably releases up to about 90 percent of at least one of said drugs into said inner layer within about thirty days of being connected to the blood vessel, said amphiphilic block copolymer including a network including both hydrophobic and hydrophilic polymer chains that can swell in both hydrophobic and hydrophilic solvents, said at least one drug formulated to inhibit stenosis, vascular narrowing, thrombosis or combinations thereof, and a barrier layer to inhibit release of at least one of said drugs from said first drug layer into said inner layer.