Patent ID: 8318701

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof wherein B is hypoxanthinyl; Z is O, S, or C(R k ) 2 ; R 3e is F, Cl, Br or I; A 6k is —CH 2 P(Y k )(A 5k )(Y k2 A 5k ), —CH 2 P(Y k )(A 5k )(A 5k ), or —CH 2 P(Y k )(Y k2 A 5k )(Y k2 A 5k ), optionally substituted with R k ; A 5k is H, alkyl, alkenyl, alkynyl, amino, amino acid, alkoxy, aryloxy, cyano, haloalkyl, cycloalkyl, aryl, haloaryl, or heteroaryl, optionally substituted with R k ; Y k is O or S; Y k2 is O, N(R k ), or S; each R 2 and R 2a is independently selected from the group consisting of H, halogen, alkyl, alkenyl, alkynyl, amino, amino acid, alkoxy, aryloxy, cyano, azido, haloalkyl, cycloalkyl, aryl, haloaryl, and heteroaryl; and each R k is independently selected from the group consisting of H, halogen, alkyl, alkenyl, alkynyl, amino, amino acid, alkoxy, aryloxy, cyano, azido, haloalkyl, cycloalkyl, aryl, haloaryl, and heteroaryl.