Patent ID: 7790197

Claim:
A wet granulated pharmaceutical composition comprising: a) from 1 to 40 w/w % of amorphous atorvastatin, or a pharmaceutically acceptable salt thereof, b) from 1 to 15 w/w % of a disintegrant selected from the group consisting of sodium starch glycolate, starch, corn starch, pregelatinized starch, sodium alginate, powdered cellulose, hydroxypropylcellulose, magnesium aluminum silicate and polacrilin potassium, c) less than 2 w/w % of an alkalinizing agent, in which said alkalizing agent is selected from the group consisting of alkaline earth metal salts, amine polymers and amide polymers, and, d) wherein said disintegrant results in an atorvastatin composition which contains less than about 3 w/w % atorvastatin lactone.