Patent ID: 7858635

Claim:
A compound formula (XX) or pharmaceutically acceptable salts thereof, wherein Each of R 1 , R 2 , R 3 is independently Q 1 or Q 2 ; Z 1 is —N(Q 1 )— or —N(Q 2 ); Z 2 is N; L is a bond or —CH 2 —; G is G 1 is —N—; G 2 is absent or a C 1-3 alkyl; G 3 is an aryl or heteroaryl, each optionally substituted with 1-3 substituents independently selected from Q 2 and Q 3 ; and G 5 is 0 or 1 when G 2 is absent or 0 when G 2 is a C 1-3 alkyl; Each Q 1 is independently halo, —CN, —NO 2 , —OQ 2 , —S(O) z Q 2 , —S(O) z N(Q 2 ) 2 , —N(Q 2 ) 2 , —C(O)OQ 2 , —C(O)-Q 2 , —C(O)N(Q 2 ) 2 , —C(O)N(Q 2 )(OQ 2 ), —N(Q 2 )C(O)-Q 2 , —N(Q 2 )C(O)N(Q 2 ) 2 , —N(Q 2 )C(O)O-Q 2 , —N(Q 2 )S(O) z -Q 2 or aliphatic optionally including 1-3 substituents independently selected from Q 2 or Q 3 ; Each Q 2 is independently H, aliphatic, cycloaliphatic, aryl, arylalkyl, heterocyclic, or heteroaryl ring, each optionally including 1-3 substituents independently selected from Q 3 ; Each Q 3 is halo, oxo, —CN, —NO 2 , —CF 3 , —OCF 3 , —OH, —S(O) z Q 4 , —N(Q 4 ) 2 , —COOQ 4 , —C(O)Q 4 , —OQ 4 , or C 1-4 alkyl optionally substituted with halo, oxo, —CN, —NO 2 , —CF 3 , —OCF 3 , —OH, —SH, —S(O) z H, —NH 2 , or —COOH; Each Q 4 is aliphatic, cycloaliphatic, aryl, aralkyl, heterocycloaliphatic, heteroaralky, or heteroaryl, each optionally including 1-3 substituents selected from halo, oxo, —CN, —NO 2 , —CF 3 , —OCF 3 , —OH, —SH, —S(O) z H, —NH 2 , or —COOH; Each Q 5 is a heterocyclic ring optionally including 1-3 substituents selected from halo, C 1-4 alkyl, oxo, —CN, —NO 2 , —CF 3 , —OCF 3 , —OH, —SH, —S(O) z H, —NH 2 , —COOH; Each i is independently 1, 2, or 3; Each m and n is independently 2; Each p is 0 or 1; Each y is independently 0 or 1; Each t is 1 to 4; and Each z is independently 0, 1, or 2.