Patent ID: 8143288

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein is a single or double bond; is a single or double bond; when is a single bond, X is selected from the group consisting of O, CH 2 , and CHR 3 ; when is a double bond, X is selected from the group consisting of CH and CR 3 ; when is a single bond, Y is selected from the group consisting of 0, CH 2 , and CHR 4 ; when is a double bond, Y is selected from the group consisting of CH and CR 4 ; n and m are independently 1, 2, or 3; p is 1; R 1 and R 2 are independently selected from the group consisting of alkoxy, alkoxyalkoxyalkyl, alkoxyalkyl, alkyl, alkylsulfenylalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, aryl, arylalkoxy, arylalkoxyalkyl, arylalkyl, arylcarbonyl, aryloxy, aryloxyalkyl, arylsulfenylalkyl, arylsulfinylalkyl, arylsulfonylalkyl, carboxyalkyl, cycloalkenyl, cycloalkenylalkyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkoxy, heterocyclylalkoxyalkyl, heterocyclylalkyl, heterocyclylcarbonyl, heterocyclyloxy, heterocyclyloxyalkyl, —NR a R b , and (NR a R b )alkyl; R 3 and R 4 are independently selected from the group consisting of hydrogen, alkenyl, alkoxy, alkoxycarbonyloxy, alkyl, alkylsulfonyl, alkylsulfonyloxy, aryl, arylalkyl, azido, hydroxy, —NR a R b , (NR a R b )alkyl, and (NR a R b )carbonyloxy; wherein the alkenyl and the alkyl can optionally form a saturated or unsaturated cyclic structure, respectively, with an adjacent carbon atom; R 5 and R 6 are independently selected from the group consisting of hydrogen, alkenyl, alkoxycarbonyl, alkyl, alkylcarbonyl, aryl, arylalkyl, heterocyclylalkylcarbonyl, and heterocyclylcarbonyl; R 7 and R 8 are independently selected from the group consisting of hydrogen, alkenyl, alkoxy, alkyl, halo, and haloalkyl; and R a and R b are independently selected from the group consisting of hydrogen, alkenyl, alkyl, alkylcarbonyl, aryl, arylalkyl, arylalkylcarbonyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, and heterocyclylalkyl.