Patent ID: 8414893

Claim:
An isolated antibody that specifically binds to amyloid-beta 1-42 (Aβ42) with a dissociation rate constant (k d ) of about 1×10 −4 s −1 or less as measured by surface plasmon resonance, and that comprises a light chain and a heavy chain, comprising: (a) a CDRL1 sequence as set forth in SEQ ID NO: 15; (b) a CDRL2 sequence as set forth in SEQ ID NO: 16; (c) a CDRL3 sequence as set forth in SEQ ID NO: 17; (d) a CDRH1 sequence as set forth in SEQ ID NO: 18; (e) a CDRH2 sequence as set forth in SEQ ID NO: 19; and (f) a CDRH3 sequence as set forth in SEQ ID NO: 20.