Patent ID: 7803829

Claim:
A method for inhibiting a BCR-ABL inhibitor-resistant tyrosine kinase activity comprising contacting a BCR-ABL inhibitor-resistant tyrosine kinase polypeptide with an effective amount of the compound of formula (I) wherein R is an optionally substituted aryl or heteroaryl group; R 1 and R 2 represent, the same or different and independently from each other, a hydrogen atom, a straight or branched C 1 -C 3 alkyl or, taken together with the carbon atom to which they are bonded, R 1 and R 2 may form a C 3 -C 6 cycloalkyl group; with the proviso that at least one of R 1 and R 2 is other than a hydrogen atom; R 3 is a hydrogen or halogen atom or a group selected from hydroxy, cyano, straight or branched C 1 -C 3 alkyl or C 1 -C 3 alkoxy.