Patent ID: 7329675

Claim:
A compound of the general formula (I): wherein represents a bicyclic ring system, of 9 ring members, in which the ring is an azaheterocycle, selected from imidazolyl, pyrrolyl, pirrolinyl and pyrazolyl, and the ring represents a benzene ring; R 1 represents hydrogen or a straight- or branched-chain alkyl group of 1 to about 4 carbon atoms, optionally substituted by hydroxy or one or more halogen atoms; R 2 represents heterocycloalkyl; R 3 represents —C(═O)NHR 6 , —C(═O)CH 2 R 6 , or —OCH 2 R 6 ; R 4 and R 5 , which may be the same or different, each represent a hydrogen atom, or an alkyl, aryl, arylalkyl, cycloalkyl, heteroaryl, or heteroarylalkyl group; R 6 is optionally substituted pyridyl or isoxazolyl; A 1 represents a direct bond, or a straight or branched C 1-6 alkylene chain optionally substituted by hydroxyl, alkoxy, oxo, cycloalkyl, aryl or heteroaryl, or A 1 represents a straight or branched C 2-6 alkenylene or C 2-6 alkynylene chain; Z 1 represents a direct bond, an oxygen or sulphur atom or NH; n and m each represent zero or 1, provided that n is 1 when m is zero and n is zero when m is 1; and N-oxides thereof, and pharmaceutically acceptable salts of the compounds of formula (I) and N-oxides thereof.