Patent ID: 8586579

Claim:
A compound of formula (I) wherein X is O or S; Y is —C(O)— or —S(O) 2 —; A is a single bond or double bond, with the proviso that when X is S then A is a double bond; R 1 is hydrogen, C 1-7 alkyl, C 1-7 haloalkyl, C 2-7 alkenyl, C 2-7 alkynyl, cycloalkyl, heterocycloalkyl, aryl, aryl annellated to heterocycloalkyl, heteroaryl, or —N(R 6 ) 2 , wherein C 1-7 alkyl, C 1-7 haloalkyl, C 2-7 alkenyl, C 2-7 alkynyl are optionally substituted by one to three substituents selected independently from the group consisting of cyano, cycloalkyl, heterocycloalkyl, aryl, aryl annellated to heterocycloalkyl, heteroaryl, —C(O)N(R 6 ) 2 , —N(R 6 ) 2 , —NH(CO)—C 1-7 alkyl, hydroxy, C 1-7 alkoxy, C 1-7 haloalkoxy, oxo, and —S(O) 2 R 7 , and wherein cycloalkyl, heterocycloalkyl, aryl, aryl annellated to heterocycloalkyl and heteroaryl are optionally substituted by one to three independent R 4 ; R 2 and R 3 are each independently hydrogen, halogen, C 1-7 alkyl, C 1-7 haloalkyl, hydroxy, C 1-7 alkoxy or C 1-7 haloalkoxy; R 4 is halogen, cyano, C 1-7 alkyl, C 1-7 haloalkyl, cycloalkyl, heterocycloalkyl, aryl, aryl annellated to heterocycloalkyl, heteroaryl, —C(O)N(R 6 ) 2 , —N(R 6 ) 2 , —NH(CO)—C 1-7 alkyl, hydroxy, C 1-7 alkoxy, C 1-7 haloalkoxy, oxo, —S(O) 2 R 7 , or C 1-7 alkyl substituted by one to three substituents selected independently from the group consisting of cyano, hydroxy, C 1-7 alkoxy, and C 1-7 haloalkoxy, wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are optionally substituted by one to three independent R 5 ; R 5 is halogen, cyano, C 1-7 alkyl, C 1-7 haloalkyl, hydroxy, C 1-7 alkoxy, C 1-7 haloalkoxy, or oxo; R 6 is hydrogen or C 1-7 alkyl; R 7 is hydrogen, C 1-7 alkyl, or aryl, wherein aryl is optionally substituted by one to three independent R 5 ; or a pharmaceutically acceptable salt or ester thereof.