Patent ID: 7005533

Claim:
A method of preparation of compounds represented by formula (I): wherein the method comprises the following steps: (a) contacting a least one acid halide represented by formula (II): ACOX (II) with at least one phosphite represented by formula (V): P(OR 1 )(OR 2 )(OR) (V) wherein: X represents a halogen atom, A represents a group of formula —(CH 2 ) n —R 4 , n is a whole number from 0 to 24 inclusive, R 4 represents a hydrogen atom, an alkyl group, an aryl group, a heterocycle or a group with the formula —NR 5 R 6 , R 5 and R 6 , which are the same or different, represent a hydrogen atom or an alkyl group, R 1 , R 2 and R, which are the same or different, represent an alkyl, aryl, acyloxyalkyl, or heterocycle group, to form an α-ketophosphonate represented by formula (III): wherein A, R 1 and R 2 are as defined above; (b) contacting the α-ketophosphonate obtained in the previous step with at least one silyl phosphite represented by formula (IV): P[(OSialk 3 ) x ][OR 3 ] 3-x (IV) wherein: alk is a C 1-6 alkyl group, x is equal to 2 or 3, R 3 represents a hydrogen atom, an alkyl, aryl, acyloxyalkyl, or heterocycle group; and (c) hydrolysis of the compounds obtained in the previous step.