Patent ID: 7417058

Claim:
A benzsulfonamide according to formula I with its geometrical isomers, in an optically active form as enantiomers, diastereomers, as well as in the form of racemates, as well as pharmaceutically acceptable salts thereof, wherein Ar 1 is selected from the group consisting of an unsubstituted aryl group, an unsubstituted heteroaryl group, a substituted aryl group, and a substituted heteroaryl group; R 1 is hydrogen or a C 1 -C 6 -alkyl group; R 2 is hydrogen, —COOR 3 , —CONR 3 R 3′ , OH, a C 1 -C 4 alkyl substituted with an OH group, a hydrazido carbonyl group, a sulfate, a sulfonate, an amine or an ammonium salt; n is either 0 or 1; Y is a cyclic amine having the formula whereby, L 1 and L 2 are independently selected from the group consisting of C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, C 4 -C 8 -cycloalkyl, C 4 -C 8 -cycloalkyl containing 1-3 heteroatoms, C 4 -C 8 -cycloalkyl fused with an aryl, C 4 -C 8 -cycloalkyl fused with a heteroaryl, an unsubstituted aryl group, an unsubstituted heteroaryl group, a substituted aryl group, a substituted heteroaryl group, aryl-C 1 -C 6 -alkyl, heteroaryl- C 1 -C 6 -alkyl, —C(O)—OR 3 , —C(O)—R 3 , —C(O)—NR 3′ R 3 , —NR 3′ R 3 , —NR 3′ C(O)R 3 , —NR 3′ C(O)NR 3′ R 3 , —(SO)R 3 , —(SO 2 )R 3 , —NHSO 2 R 3 , and —SO 2 NR 3′ R 3 , with R 3 and R 3′ independently selected from the group consisting of H, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, an unsubstituted aryl group, an unsubstituted heteroaryl group, a substituted aryl group, and a substituted heteroaryl group, aryl-C 1 -C 6 -alkyl, and heteroaryl-C 1 -C 6 -alkyl; R 6 is selected from the group consisting of hydrogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, OH, halogen, nitro, cyano, sulfonyl, and oxo (═O); and n′ is an integer from 0 to 4.