Patent ID: 8008286

Claim:
A method therapeutic treatment of neuropathic pain in a mammal, comprising administering to said mammal an effective amount of a compound having the formula: wherein X is hydroxyl, phosphate, phosphonate, or alpha-substituted phosphonate; R 1 is hydrogen, halo, tri-fluoromethyl, (C 1 -C 10 ) alkyl, (C 1 -C 10 ) alkyl substituted with halo, hydroxy-, (C 1 -C 10 ) alkoxy, or cyano; and R 2 is (C 1 -C 20 )alkyl, cycloalkyl substituted alkyl, (C 2 -C 20 )alkenyl, (C 2 -C 20 )alkynyl, aryl, alkyl substituted aryl, arylalkyl or aryl substituted arylalkyl; wherein one or more of the carbon atoms in the R 2 groups can be independently replaced with non-peroxide oxygen, sulfur or NR 8 ; wherein R 8 is hydrogen, or an (C 1 -C 10 ) alkyl group; wherein the alkyl, alkenyl, and alkynyl groups in R 2 are optionally substituted with oxo; n is 2; and or a pharmaceutically acceptable salt or ester thereof.