Patent ID: 8470333

Claim:
An immunogenic composition comprising a chimeric peptide, wherein the chimeric peptide comprises a HER-2 B epitope, a T helper (Th) epitope, and a linker joining the HER-2 B epitope to the Th epitope, wherein: the HER-2 B epitope consists of the sequence selected from the group consisting of: SEQ ID NO: 2 CHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVA,; SEQ ID NO: 3 VACAHYKDPPFCVA,; SEQ ID NO: 4 VARCPSGVKPDLSYMPIWKFPDEEGACQPL,; SEQ ID NO: 5 IWKFPDEEGACQPL,; SEQ ID NO: 7 ACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEK,; SEQ ID NO: 8 CPLHNQEVTAEDGTQRCEK,; and SEQ ID NO: 9 CPINCTHSCVDLDDKGCPAEQRAS,; the Th epitope comprises the sequence selected from the group consisting of: KLLSLIKGVIVHRLEGVE,; SEQ ID NO: 10 NSVDDALINSTIYSYFPSV,; SEQ ID NO: 11 PGINGKAIHLVNNQSSE,; SEQ ID NO: 12 QYIKANSKFIGITEL,; SEQ ID NO: 13 FNNFTVSFWLRVPKVSASHLE,; SEQ ID NO: 14 LSEIKGVIVHRLEGV,; SEQ ID NO: 15 FFLLTRILTIPQSLN,; SEQ ID NO: 16 and TCGVGVRVRSRVNAANKKPE,; SEQ ID NO: 17 the linker comprises a sequence that is from 1 to 15 amino acids in length.