Patent ID: 8399714

Claim:
A process for the synthesis of an (E)-stilbene derivative of formula (I)-(E) or a (Z)-stilbene derivative of formula (I)-(Z) wherein: R is hydrogen or an OH group, R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are independently a hydrogen or a substituent selected from the group consisting of: a halogen; a nitro group; a linear or branched C 1 -C 6 alkyl group; a linear or branched C 2 -C 6 alkenyl group; a C 3 -C 10 cycloalkyl group; a cycloalkylalkyl group wherein the cycloalkyl and alkyl groups are as defined above; a monocyclic, bicyclic or tricyclic C 6 -C 14 aryl group; a C 7 -C 16 aralkyl group; and a C(═O)R 10 group wherein R 10 is a linear or branched C 1 -C 6 alkyl group, a C 3 -C 10 cycloalkyl group, a cycloalkylalkyl group wherein the cycloalkyl and alkyl groups are as defined above, a monocyclic, bicyclic or tricyclic C 6 -C 14 aryl group, a C 7 -C 16 aralkyl group, an OR 11 group wherein R 11 is a hydrogen, a linear or branched C 1 -C 6 alkyl group, a C 3 -C 10 cycloalkyl group, a cycloalkylalkyl group wherein the cycloalkyl and alkyl groups are as defined above, a monocyclic, bicyclic or tricyclic C 6 -C 14 aryl group or a C 7 -C 16 aralkyl group, or an NR 12 R 13 group wherein R 12 and R 13 independently are a hydrogen, a linear or branched C 1 -C 6 alkyl group, a C 3 -C 10 cycloalkyl group, a cycloalkylalkyl group wherein the cycloalkyl and alkyl groups are as defined above, a monocyclic, bicyclic or tricyclic C 6 -C 14 aryl group or a C 7 -C 16 aralkyl group; wherein all the above alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl radicals may be unsubstituted or substituted, comprising the step of deprotecting a compound of formula (II)-(E) or (II)-(Z) wherein A is a hydrogen or an OR′ 1 group and R 1 , R 2 , R 3 and R′ 1 independently are a linear or branched C 1 -C 6 alkyl group or a C 7 -C 16 aralkyl group, optionally substituted on the aryl part by one or more C 1 -C 4 alkoxy or halogen groups, wherein the deprotecting step is carried out by the use of an aluminium halide and of a tertiary amine of formula NR a R b R c wherein R a , R b and R c are independently a linear or branched C 1 -C 4 alkyl group.