Patent ID: 7256198

Claim:
A compound of formula I: or a stereoisomer, or pharmaceutically-acceptable salt thereof; wherein: R 1 and R 2 are independently hydrogen, halogen, alkyl, aryl, heteroaryl, or R 1 and R 2 together with the carbon atom to which they are attached, form a C 3 -C 7 carbocyclyl or a C 3 -C 7 heterocycle; R 3 and R 17 are independently, hydrogen and alkyl; R 15 and R 16 are independently, hydrogen, alkyl, or aryl, provided that R 15 and R 16 are not both aryl; R 4 is hydrogen, halogen, alkyl, nitrile, carboxyl, hydroxy, amino, R 7 R 8 N—, alkoxy, or perfluoroalkoxy; X is cyano, perfluoroalkoxy, R 5 is alkyl, aryl, heteroaryl, heterocycle, or carbocyclyl; R 6 is hydrogen or C 1 -C 3 alkyl; R 7 and R 8 are independently hydrogen, alkyl, aryl, heteroaryl, aralkyl, heteroaralkyl, alkanoyl, perfluoroalkanoyl, aroyl, heteroaroyl, aralkanoyl, heteroaralkanoyl, or R 7 and R 8 together with the nitrogen to which they are attached form a 5 to 10 member optionally substituted monocyclic or bicyclic ring system, which may further contain heteroatoms selected from oxygen, nitrogen or sulfur, provided that no ring may contain more than 3 heteroatoms; and R 9 is hydrogen, alkyl, aryl, heteroaryl, aralkyl, C 4 -C 12 heteroaralkyl, or C 3 -C 12 carbocyclyl.