Patent ID: 8476255

Claim:
A compound of formula (I): or the tautomeric form, stereoisomer, pharmaceutically acceptable salt or composition or prodrug thereof; wherein R 1 and R 2 represent substituted or unsubstituted groups selected from aryl, cycloalkyl, cycloalkenyl, arylalkenyl, heteroarylalkenyl, arylalkynyl, heterocyclyl and heteroaryl; R represents H, or substituted or unsubstituted groups selected from linear or branched alkyl, aryl, heteroaryl and heterocyclyl; X represents a group selected from —CONR 4 —, —NR 4 SO 2 —, —SO 2 NR 4 —, —SO 2 O—, —O—SO 2 —, —CONR 4 CONR 4 —, —NR 4 CO—, —OCONR 4 —, —NR 4 CONR 4 —, —NR 4 — and —O—; R 4 represents H, or substituted or unsubstituted groups selected from alkyl, aryl, heterocyclyl, heteroaryl, cycloalkyl and cycloalkenyl; Ar represents substituted or unsubstituted groups selected from aryl and heteroaryl; R 3 represents a group selected from ortho substituted aniline, phenol, amino aryl, hydroxy aryl, amino heteroaryl and —OR 5 ; R 5 represents a group selected from H, -COR 6 , substituted or unsubstituted groups selected from alkyl, aryl and heterocyclyl; R 6 represents substituted or unsubstituted groups selected from alkyl, aryl and heterocyclyl; wherein n=0 or 1, o=0-1, p=1, q=0-3; with the proviso that if X=—OCONH—, then n and p=1; and when the groups R, R 1 , R 2 , R 4 and Ar have one or more substituents , the substituents are selected from halogens; hydroxy; nitro; cyano; azido; nitroso; amino; hydrazine; formyl; alkyl; alkenyl; alkynyl; haloalkyl group; haloalkoxy; aralkoxy; cycloalkyl; aryl; alkoxy; aryloxy; acyl; acyloxy; acyloxyacyl; heterocyclyl; heteroaryl; alkylamino; acylamino; alkoxycarbonyl; aryloxycarbonyl; alkylsulfonyl; arylsulfonyl; alkylsulfinyl; arylsulfinyl; alkylthio; arylthio; sulfamoyl; alkoxyalkyl and carboxylic acids and its derivatives; the substituents which in turn are optionally further substituted with hydroxy; halogens; nitro; cyano; azido; nitroso; amino; hydrazine; alkyl; alkoxy; aryl; cycloalkyl and heteroaryl.