Patent ID: 8138176

Claim:
A compound of the formula in which R is deuterium, halogen or hydrogen; R 1 is aryl-C 0 -C 4 -alkyl or heterocyclyl-C 0 -C 4 -alkyl, which radicals are unsubstituted or substituted by 1-4 C 1 -C 8 alkoxy, C 1 -C 8 alkoxycarbonyl, C 2 -C 8 alkyl, C 0 -C 8 alkylcarbonyl, C 1 -C 8 alkylsulphonyl, optionally substituted aryl, aryl-C 0 -C 4 alkoxycarbonyl, cyano, halogen, optionally substituted heterocyclyl, hydroxy, nitro, oxo, tri-C 1 -C 4 -alkylsilyl, trifluoromethoxy or trifluoromethyl; R 2 is a) deuterium, halogen, hydroxy, cyano or hydrogen; or b) C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 1 -C 8 alkoxy, C 1 -C 4 alkoxycarbonyl-C 1 -C 4 alkyl, C 1 -C 8 alkyl, C 0 -C 4 alkylcarbonyl, aryl-C 0 -C 4 alkyl, carboxy-C 1 -C 4 alkyl, C 3 -C 8 cycloalkyl or heterocyclyl-C 0 -C 4 alkyl, which radicals are unsubstituted or substituted by 1-4 C 1 -C 8 alkoxy, C 1 -C 8 alkoxycarbonyl, C 1 -C 8 alkyl, C 0 -C 8 alkylcarbonyl, C 1 -C 8 alkylsulphonyl, optionally substituted aryl, aryl-C 0 -C 4 alkoxycarbonyl, cyano, halogen, optionally substituted heterocyclyl, hydroxy, nitro, oxo, tri-C 1 -C 4 alkylsilyl, trifluoromethoxy or trifluoromethyl; Q is sulphur; m is a number 1; and n is a number 1; or a pharmaceutically acceptable salt thereof, wherein the heterocyclyl in R 1 and R 2 , independently of one another, stands for a saturated, partially saturated or unsaturated, 4-8-membered monocyclic ring system, a saturated, partially saturated or unsaturated, 7-12-membered bicyclic ring system or a partially saturated or unsaturated, 9-12-membered tricyclic ring system which comprises an N, O or S atom in at least one of the rings; the optional substituents on the optionally substituted aryl in R 1 and R 2 , independently of one another, are selected from the group consisting of C 1 -C 8 alkoxy, C 1 -C 8 alkoxycarbonyl, C 1 -C 8 alkyl, C 0 -C 8 alkylcarbonyl, C 1 -C 8 alkylsulphonyl, aryl, aryl-C o -C 4 alkoxycarbonyl, cyano, halogen, heterocyclyl, hydroxy, nitro, tri-C 1 -C 4 alkylsilyl, trifluoromethoxy and trifluoromethyl; and the optional substituents on the optionally substituted heterocyclyl in R 1 and R 2 , independently of one another, are selected from the group consisting of C 1 -C 8 alkoxy, C 1 -C 8 alkoxycarbonyl, C 1 -C 8 alkyl, C 0 -C 8 alkylcarbonyl, C 1 -C 8 alkylsulphonyl, aryl, aryl-C o -C 4 alkoxycarbonyl, cyano, halogen, heterocyclyl, hydroxy, nitro, oxo, tri-C 1 -C 4 alkylsilyl, trifluoromethoxy and trifluoromethyl.