Patent ID: 8084621

Claim:
A compound of Formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 is selected from the group consisting of hydrogen, halo, alkyl, cycloalkyl, aryl, heteroaryl, heteroalicyclic, hydroxy, alkoxy, —C(O)R 7 , —NR 8 R 9 , —(CH 2 ) n R 10 and —C(O)NR 11 R 12 ; R 2 is selected from the group consisting of hydrogen, halo, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, nitro, cyano, —NR 8 R 9 , —NR 8 C(O)R 9 , —C(O)R 7 , aryl, heteroaryl, —C(O)NR 11 R 12 , S(O) 2 NR 8 R 9 and —SO 2 R 13 ; R 3 is selected from the group consisting of hydrogen, halo, alkyl, haloalkyl, hydroxy, alkoxy, —C(O)R 7 , —NR 8 R 9 , aryl, heteroaryl, —NR 8 S(O) 2 R 9 , —S(O) 2 NR 8 R 9 , —NR 8 C(O)R 9 , —NR 8 C(O)OR 9 and —SO 2 R 13 ; R 4 is selected from the group consisting of hydrogen, halo, alkyl, hydroxy, alkoxy and —NR 8 R 9 ; R 5 is selected from the group consisting of hydrogen, alkyl and —C(O)R 14 ; R 6 is selected from the group consisting of hydroxy, alkoxy, aryloxy, —N(R 15 )(CH 2 ) r R 16 , —NR 8 R 9 and —N(R 17 )—CH(R 18 )—CR 19 (OH)—CH(R 20 )Z; R 7 is selected from the group consisting of hydrogen, hydroxy, alkoxy and aryloxy; R 8 and R 9 are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl and heteroaryl; or R 8 and R 9 together with the atoms to which they are attached may form a heteroalicyclic ring; R 10 is selected from the group consisting of hydroxy, —C(O)R 7 , —NR 8 R 9 and —C(O)NR 8 R 9 ; R 11 and R 12 are each independently selected from the group consisting of hydrogen, alkyl and aryl; or R 11 and R 12 together with the nitrogen atom to which they are attached may form a heteroalicyclic ring; R 13 is selected from the group consisting of alkyl, aryl, arylalkyl, heteroaryl and heteroarylalkyl; R 14 is selected from the group consisting of hydroxy, alkoxy, aryloxy and —NR 8 R 9 ; R 15 is selected from the group consisting of hydrogen and alkyl; R 16 is selected from the group consisting of hydroxy, —NR 8 R 9 , —C(O)R 7 , aryl, heteroaryl, —N + (O − ) R 8 R 9 , —N(OH) R 8 and —NHC(O)R a , wherein R a is selected from the group consisting of unsubstituted alkyl, haloalkyl and arylalkyl; R 17 , R 18 , R 19 and R 20 are each independently selected from the group consisting of hydrogen and alkyl; Z is selected from the group consisting of aryl, heteroaryl and —NR 8 R 9 ; n and r are each independently an integer from 1 to 4.