Patent ID: 8554487

Claim:
A method of analyzing reliability of genotype data at a plurality of different biallelic polymorphic sites, comprising: connecting points representing genotype data plotted in each of a plurality of two-dimensional graphs to the origin of the two-dimensional graph to form straight lines, wherein a first axis of each two dimensional graph represents a first signal-to-noise ratio (SNR 1 ) of experimental data indicating A1 of the genotype and the second axis of each two dimensional graph represents a second signal-to-noise ratio (SNR 2 ) of experimental data indicating A2 of the genotype, wherein each graph contains points representing genotype data for a single biallelic polymorphic site selected from a plurality of different biallelic polymorphic sites; obtaining angles between adjacent straight lines; extracting the two largest angles from the obtained angles; classifying the genotype data for each graph into three genotype groups separated by the two extracted largest angles, wherein the three genotype groups are A1A1, A1A2, and A2A2; and analyzing the reliability of the classified results of each of the graphs using the three groups of the genotype data separated by the two extracted largest angles such that for each graph if at least one of the two extracted largest angles is less than a first predetermined angle or if an angle of the center group among the three groups is greater than a second predetermined angle, judging that genotype classification of the graph is incorrect; if the two extracted largest angles are greater than the first predetermined angle, judging that genotype classification of the graph is correct; or if the two extracted largest angles are less than the first predetermined angle and the angle of the center group among the three groups is less than the second predetermined angle, judging that genotype classification of the graph is correct, but that a review of the experiment of determining the genotype data of the graphs is required; and wherein the steps of the method are executed on a suitably programmed computer.