Patent ID: 7425562

Claim:
A compound according to general formula (I) or general formula (II): wherein: R 1 ═C 0-7 -alkyl (when C═0, R 1 is hydrogen), C 3-6 -cycloalkyl or Ar—C 0-7 -alkyl; Ar is an aromatic moiety which is a 5- or 6-membered monocyclic or 9- or 10-membered bicyclic ring, which is unsaturated, wherein the aromatic ring is optionally substituted with R 19 ; Z=O, S, CR 2 R 3 or NR 4 , where R 4 is chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl or Ar—C 0-7 -alkyl; P 1 =CR 5 R 6 , P 2 =CR 7 R 8 , Q=CR 9 R 10 or NR 11 , where R 11 is chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl or Ar—C 0-7 -alkyl; Each of R 2 , R 3 , R 5 , R 6 , R 7 , R 8 , R 9 and R 10 is independently chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl, Ar—C 0-7 -alkyl, O—C 0-7 -alkyl, O—C 3-6 -cycloalkyl, O—Ar—C 0-7 -alkyl, S—C 0-7 alkyl, S—C 3-6 -cycloalkyl, S—Ar—C 0-7 -alkyl, NH—C 0-7 -alkyl, NH—C 3-6 -cycloalkyl, NH—Ar—C 0-7 -alkyl, N(C 0-7 -alkyl) 2 , N(C 3-6 -cycloalkyl) 2 or N(Ar—C 0-7 -alkyl) 2 ; Y=CR 12 R 13 —CO, where R 12 , R 13 are chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl or Ar—C 0-7 -alkyl; in the group (X) o , X=CR 14 R 15 , where R 14 and R 15 are independently chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl and Ar—C 0-7 -alkyl and o is a number from zero to three; in the group (W) n , W=O, S, C(O), S(O) or S(O) 2 or NR 16 , where R 16 is chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl and Ar—C 0-7 -alkyl and n is zero or one; in the group (V) m , V=C(O), C(S), S(O), S(O) 2 , S(O) 2 NH, OC(O), NHC(O), NHS(O), NHS(O) 2 , OC(O)NH, C(O)NH or CR 17 R 18 , where R 17 and R 18 are independently chosen from C 0-7 -alkyl, C 3-6 -cycloalkyl, Ar—C 0-7 -alkyl and m is a number from zero to three, provided that when m is greater than one, (V) m contains a maximum of one carbonyl or sulphonyl group; U=a 5- to 7-membered monocyclic ring selected from the group consisting of: wherein R 19 is: C 0-7 -alkyl, C 3-6 -cycloalkyl, Ar—C 0-7 -alkyl, O—C 0-7 -alkyl, O—C 3-6 -cycloalkyl, O—Ar—C 0-7 -alkyl, S—C 0-7 -alkyl, S—C 3-6 -cycloalkyl, S—Ar—C 0-7 -alkyl, NH—C 0-7 -alkyl, NH-C 3-6 -cycloalkyl, NH—Ar—C 0-7 -alkyl, N(C 0-7 -alkyl) 2 , N(C 3-6 -cycloalkyl) 2 or N(Ar—C 0-7 -alkyl) 2 ; or, when part of a CHR 19 or CR 19 group, R 19 may be halogen; A is chosen from: CH 2 , CHR 19 , O, S and NR 20 ; where R 19 is as defined above; and R 20 is chosen from: C 0-7 -alkyl, C 3-6 -cycloalkyl and Ar—C 0-7 -alkyl; B, D and G are independently chosen from: CR 19 , where R 19 is as defined above, N and N-oxide; E is chosen from: CH 2 , CHR 19 , O, S and NR 20 , where R 19 and R 20 are defined as above; J, L, M, R, and T are independently chosen from: —CR 19 , N and N-oxide, where R 19 is as defined above; T 5 is chosen from: CH or N; q is a number from one to three, thereby defining a 5-, 6- or 7-membered ring or a salt thereof.