Patent ID: 7767649

Claim:
A compound of Formulae (V)-(XIV): wherein n is 1 or 2; m is 1, 2, 3 or 4; R 1 is selected from the group consisting of hydrogen, methyl, isopropyl, isobutyl, sec-butyl, —CH 2 OH, —CH(OH)CH 3 , —CH 2 CO 2 H, —CH 2 CH 2 CO 2 H, —CH 2 CONH 2 , —CH 2 CH 2 CONH 2 , —CH 2 CH 2 SCH 3 , CH 2 SH, —CH 2 (CH 2 ) 3 NH 2 or —CH 2 CH 2 CH 2 NHC(NH)NH 2 , phenyl, benzyl, 4-hydroxybenzyl, 2-imidazolyl and 2-indolyl; R is selected from the group consisting of hydrogen, C 1-6 alkyl, phenyl, benzyl, —C(CH 3 )═CH 2 or —CH 2 C(O)N(CH 3 ) 2 ; either R 4 is hydrogen and R 5 is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl, tert-butyl, cyclopentyl, cyclohexyl, phenyl, benzyl, phenethyl or 3-pyridyl; or R 4 is methyl and R 5 is selected from the group consisting of methyl, methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl, isopropoxycarbonyl, butoxycarbonyl, isobutoxycarbonyl, sec-butoxycarbonyl, tert-butoxycarbonyl and cyclohexyloxycarbonyl; R 7 is hydrogen; R 8 is substituted aryl; and pharmaceutically acceptable salts thereof.