Patent ID: 7384917

Claim:
A compound of the following formula: X 0 -Pro-X 1 -A 5 -A 1 -A 3 -Pro-A 1 -Pro-A 1 -A 5 -Pro-X 1 -X 1 -X 1 -A 4 wherein A 1 is Leu, Lys, Mg, His, Orn, Asn or Gln; A 3 is Asp or Glu; A 4 is Lys, Arg, Orn, Ala, Thr, Asn, or Gln; A 5 is Gly, Ala, Val, Met, Leu, Norleucine or Ile; X 2 is absent or is a peptide of from 1 to 35 amino acid residues; X 1 is Ser or Thr; X 0 is absent or is a peptide of from 1 to 35 amino acid residues; wherein X 0 is not Glu-Val-Lys-Tyr-Asp-Pro-Cys-Phe-Gly-His-Lys-Ile-Asp-Arg-Ile-Asn-His-Val-Ser-Asn-Leu-Gly-Cys (SEQ ID NO: 11); wherein the compound is not SEQ ID NO: 1, and wherein the compound has a biological activity selected from the group consisting of vasodilation, natriuresis, diuresis and renin suppression.