Patent ID: 8338142

Claim:
A method for producing an optically active nipecotamide derivative or an optically active nipecotin derivative, comprising a step of: stereoselectively hydrolyzing a racemic nipecotamide derivative represented by the following formula (1): wherein, R 1 represents a hydrogen atom or a benzyl group, by using an enzyme source having an ability to stereoselectively hydrolyze the racemic nipecotamide derivative (1), to produce an optically active nipecotamide derivative represented by the following formula (2): wherein, * indicates an asymmetric carbon atom; and R 1 means the same as the above, and an optically active nipecotin derivative represented by the following formula (3): wherein, * and R 1 mean the same as the above, and wherein, the enzyme source having the ability to stereoselectively hydrolyze the racemic nipecotamide derivative (1) is derived from a microorganism belonging to genus Achromobacter, Cupriavidus, Pectobacterium or Staphylococcus; from the racemic nipecotamide derivative (1).