Patent ID: 8084053

Claim:
A method for preparing a solid pharmaceutical composition for parenteral injection comprising: homogeneously mixing at least one therapeutic agent that constitutes at least 40% of the composition by weight with a binder that comprises at least one carbohydrate binding agent and constitutes at least 0.5% of the composition by weight, and, at least one non-crystallization agent, so as to obtain an amorphous melt matrix, shaping the melt matrix to a needle-shaped geometry using a mold cavity such that the solid pharmaceutical composition is capable of penetrating the epidermis, cutis or mucosa of a patient by injection without the assistance of a hypodermic needle or trocar, cooling the amorphous melt matrix of the pharmaceutical composition to below the Tg of the binder, and removing the composition from the mold cavity, thereby providing a solid pharmaceutical composition.