Patent ID: 8486936

Claim:
A compound having the structure of Formula (I): or a stereoisomer, hydrate, solvate or pharmaceutically acceptable salt thereof, wherein: m is 1 or 2; n is 0, 1, or 2; X is C 1 -C 3 alkyl, halogen or CN; Y is C 1 -C 3 alkyl, halogen or CN; R 2 is selected from the group consisting of Cl, Br, —CN, alkyl, —O-aryl, —O-heteroaryl, —CH 2 -aryl, —CH 2 -heteroaryl, —NH-aryl, —SO 2 -aryl, —NH-heteroaryl, —NH-alkyl, —CH 2 —NH-alkyl, —CH 2 —N(alkyl) 2 , —CH 2 —(N-linked heterocycle), —CH 2 —(C-linked heterocycle), N-linked heterocycle, and C-linked heterocycle; R 3 , R 5 , and R 6 are independently selected from the group consisting of hydrogen, Cl, Br, —CN, alkyl, aryl, heteroaryl, C-linked heterocycle, —O-alkyl, —O-aryl, —O-heteroaryl, N-linked heterocycle, —NHalkyl, —N(alkyl) 2 , —NHaryl, —NH-heteroaryl, —CO 2 H, —CO 2 alkyl, —SO 2 alkyl, —SO 2 NH 2 , —SO 2 NHalkyl, —SO 2 N(alkyl) 2 , —NHSO 2 alkyl, —NHSO 2 aryl, —NHCONHalkyl, —NHCON(alkyl) 2 , —N(alkyl)CONH 2 , —N(alkyl)CONH(alkyl), and —N(alkyl)CON(alkyl) 2 ; and R 4 is selected from the group consisting of alkoxy, —CN, —SO 2 -alkyl, —SO 2 NH 2 , —SO 2 NH-alkyl, —NHSO 2 -alkyl, —NHSO 2 -aryl, —NHCO-alkyl, —NHCO-aryl, —NHCONH-alkyl, —NHCONH-aryl, —CONH 2 , —CONH-alkyl, —CONH-aryl, —CON(alkyl) 2 , —CON(aryl) 2 , —CO 2 H, and —CO 2 alkyl.