Patent ID: 7595169

Claim:
A method for obtaining a percent activation of aggregation or inhibition of aggregation of platelets in an anti-coagulated blood sample from an individual treated with an anti-platelet drug, comprising: (a) providing an assay device having a first channel (Test Channel) and a second channel (Control Channel); (b) introducing a first platelet activator to the first channel (Test Channel) of the assay device, the platelet activator being sensitive to an activation pathway targeted by the anti-platelet drug; (c) introducing a second platelet activator to the second channel (Control Channel) of the assay device, the second platelet activator being insensitive to the activation pathway targeted by the anti-platelet drug; (d) introducing the anti-coagulated blood sample to the assay device; (e) simultaneously measuring a level of platelet aggregation in both channels; and (f) determining a percent platelet aggregation (PA) or inhibition (PI) as follows: % PA=(Test Channel/Control Channel)*100% % PI=(1−(Test Channel/Control Channel))*100%=100%−% PA.