Patent ID: RE41209

Claim:
A cis-platinum complex of general formula Ia or Ib where each A, is a leaving group and may be the same or different, or together form a bi-dentate carboxylate or sulphate, each B, which may be the same or different, is halo, hydroxy, carboxylate, carbamate or carbonate ester, Z is a substituted unsaturated cyclic amine coordinated to Pt through the amine nitrogen atom which amine may contain one or more other heteroatoms, wherein the amine is substituted by lower C 1 -C 4 alkyl or alkoxy adjacent to the amine nitrogen atom, wherein the substituent sterically hinders access of the Pt atom to a DNA strand of a tumour ceil cell , and X is NH 3 or mono- or di-alkyl substituted NH 3 .