Patent ID: 8372848

Claim:
A composition of matter comprising a compound having the following structural formula: wherein, R 1 and R 2 are selected from H, a hydrocarbyl having up to 20 carbon atoms, and a hydrocarbyl having up to 20 carbon atoms and substituted with a group selected from hydroxy, alkoxy, amino, substituted amino, thio, alkylthio, guanidino, ureido and heterocyclyl; R 3 is selected from a hydrocarbyl having up to 20 carbon atoms, and a hydrocarbyl having up to 20 carbon atoms and substituted with a group selected from halo, haloalkyl, hydroxy, alkyl, alkoxy, alkylenedioxy, amino, substituted amino, aminoalkyl, thio, alkylthio, guanidino, ureido, heterocyclyl, heteroaryl, and heteroarylthio; R 4 is a substituted amino, —NR 6 R 7 , wherein R 6 and R 7 are selected from H and a hydrocarbyl having up to 20 carbon atoms; R 6 and R 7 , with inclusion of N, may combine to form a heterocyclic ring such as indolinyl having the formula R 5 is selected from O, S, NH, N-alkyl, N-alkenyl, N-alkynyl, N-cycloalkyl, N-aryl and N-aralkyl, n is 1 to 3; and wherein the composition is further characterized by at least one additional limitation selected from group consisting of: one or more methylene groups of a hydrocarbyl group of R3 being replaced by an oxygen atom; R 1 being selected from alkyl and aminoalkyl; R 1 being selected from (S)-Methyl, (R)-Methyl or (S)-Propyl; R 1 being (S)-Aminopropyl; R 2 being selected from (R)-Aminomethyl-(imino)-propyl, (S)-Aminomethyl-(imino)-propyl or (S)-Methylthiomethyl; R 3 being selected from alkyl, aralkyl or substituted aralkyl; R 3 being 3-bromophenethyl; R 3 being 3,5 bis-(trifluoromethyl)phenethyl; R 4 being aralkylamino; R 4 being benzylamino; R 6 and R 7 with inclusion of n, being heterocyclyl; and —NR 6 R 7 being isoindolinyl having the formula