Patent ID: 7759485

Claim:
A Process for preparing dihydropteridinones of the general formula (I) wherein the dihydropteridinone is selected from among the following dihydropteridinones of general formula (I) config. R 1 Ex. R 1 R 2 or R 2 R 3 27 H R 44 H R 55 H R 58 H R 102 H R 103 H R 105 H R 110 H R 115 H R 133 H R 134 H R 234 H R 240 H R Ex. R 4 L n —R 5 m 27 44 H 55 58 102 103 105 110 115 133 134 234 240 while the abbreviations X 1 , X 2 , X 3 , X 4 and X 5 used in the Table in each case denote a link to a position in the general formula listed in the Table instead of the corresponding groups R 1 , R 2 , R 3 , R 4 and L n -R 5 m ; comprising: reacting a compound of formula (II) wherein R 1 to R 3 are defined as specified and A is a leaving group, with a compound of formula (III) wherein R 4 , R 5 , L and m, n may be defined as specified, and subsequently isolating the product wherein the reaction is carried out in the presence of a organic sulphonic acids catalyst.