Patent ID: 6884808

Claim:
A heterocycle-containing carboxylic acid derivative represented by the following formula (I): wherein A is a group represented by the following formula (i) in which (1) E 1 is a nitrogen atom and F 1 , G 1 , H 1 and I 1 , are carbon atoms which may have a substituent; or (2) F 1 is a nitrogen atom and E 1 , G 1 , H 1 and I 1 are carbon atoms which may have a substituent; or (3) H 1 is a nitrogen atom and E 1 , F 1 , G 1 and I 1 are carbon atoms which may have a substituent, R 1 and R 2 are the same or different and each independently represents a hydrogen atom, a halogen atom, a lower alkyl group which may have a substituent, a cycloalkyl group which may have a substituent; a lower alkoxy group which may have a substituent; a cycloalkyloxy group which may have a substituent, an aryl group which may have a substituent, a heteroaryl group which may have a substituent, an aryloxy group which may have a substituent, a heteroaryloxy group which may have a substituent, a cycloalkylalkyl group which may have a substituent, an arylalkyl group which may have a substituent, a heteroarylalkyl group which may have a substituent, a cycloalkylalkyloxy group which may have a substituent, an arylalkyloxy group which may have a substituent, a heteroarylalkyloxy group which may have a substituent, an alkenyl group which may have a substituent or an alkynyl group which may have a substituent, or R 1 and R 2 are coupled together to form a cycloalkylene group which may have a substituent, a carbon group forming said cycloalkylene group may be substituted by a sulfur atom, an oxygen atom, a sulfinyl group, a sulfonyl group or >NR 4 , R 4 representing a hydrogen atom or a lower alkyl group; B is a heteroarylene group which may have a substituent, an arylene group which may have a substituent, or a group represented by the following formula: wherein R 5 represents a hydrogen atom or a lower alkyl group; and m 2 stands for 0 to 2; R 8 to R 15 are the same or different and each independently represents a hydrogen atom or a lower alkyl group; X represents an oxygen atom, a sulfur atom or >NR 4 , R 4 having the same meaning as defined above; D is an arylene group which may have a substituent; n 1 is one; M is a hydroxyl group, a lower alkoxy group or a group represented by the following formula: —NR 16 R 17 in which R 16 and R 17 are the same or different and each independently represents a hydrogen atom, a hydroxyl group, a lower alkyl group, a R 17 lower alkoxy group, a hydroxyalkyl group, an aryl group or a heteroaryl group or R 16 and are coupled together with the adjacent nitrogen atom to form an oxygen- or sulfur-containing ring; and represents a single bond or double bond; or a physiologically acceptable salt thereof.