Patent ID: 7678827

Claim:
An implant composition comprising a blend mixture of a lipophilic compound having a molecular weight of 150-4000 and a pharmaceutically effective amount of a drug, wherein the implant composition contains neither a polymeric ingredient nor an organic solvent that is miscible with or dispersible in water, wherein the implant composition is solid at a temperature of 37° C. and becomes a liquid above 37° C., and said implant composition is solidifiable in a human, and the lipophilic compound is of the formula wherein R 1 is —H, —OH, —COOH, —C n H 2n+1-2m , —COOC n H 2n+1-2m , —COO(CH 2 CH 2 O) n CH 2 CH 2 OH, —CH 2 R 3 , or R 2 , R 3 and R 4 are independently —H, —OH, —COOH, —C n H 2n+1-2m , —OOCC n H 2n+1-2m , —COOC n H 2n+1-2m , —COO(CH 2 CH 2 O) n CH 2 CH 2 OH, —C n— H 2n+1-2m COO(CH 2 CH 2 O) n CH 2 CH 2 OH, —OOCC n H 2n+1-2m COOC n′ H 2n′+1-2m′ , —COO − Na + , —COO − K + , —SO 3 H, —SO 3 − Na + , —SO 3 − K + , —NH 2 , —Cl, n, n′ and n″ are independently 0-50; and m and m′ are independently 0-10, wherein said lipophilic compound is present is an amount of at least 30 wt % based on the weight of the intraocular implant composition.