Patent ID: 8026370

Claim:
A carboxylic acid derivative containing a thiazole ring represented by formula (I): wherein R 1 and R 2 are the same or different and each is a hydrogen atom or an alkyl group, or R 1 and R 2 are bonded to each other to form a cycloalkyl group; R 3 is a hydrogen atom or an alkyl group; R 4 is a hydrogen atom, an alkyl group or an aryl group; n is an integer of 1 to 5; Y is an oxygen atom, a sulfur atom, —NR 5 —, —CONR 5 —, —NR 5 CO— or —NHCONR 5 —, wherein R 5 is a hydrogen atom, an alkyl group, a cycloalkylalkyl group, an aryl group, an arylalkyl group, an arylalkenyl group, an aryloxyalkyl group, a heteroaryl group or a heteroarylalkyl group; and Z is a cycloalkyl group, an aryl group, an arylalkyl group, an arylalkenyl group, an aryloxyalkyl group, a heteroaryl group or a heteroarylalkyl group, wherein, in the aforementioned groups, an alkyl group, a cycloalkyl group, a cycloalkylalkyl group, an aryl group, an arylalkyl group, an arylalkenyl group, an aryloxyalkyl group, a heteroaryl group and a heteroarylalkyl group each optionally have substituent, or a pharmaceutically acceptable salt thereof.