Patent ID: 8758633

Claim:
A method for forming a planar nanofluidic channel on a substrate comprising: growing a native oxide layer on a surface of a silicon substrate, the silicon substrate including a region of p-type or n-type doped silicon at the surface; etching the native oxide layer at the region of the p-type or n-type doped silicon according to a patterned wet oxide etch, the etching removing about 1 nm of material from the region forming second and third regions of doped silicon on the surface, the second and third regions being on either side of the region of p-type or n-type doped silicon, wherein the second and third regions are transmission lines; and bonding a second substrate to the surface of the silicon substrate, the second substrate comprising a first surface and a second surface, the second surface of the second substrate being bonded to the surface of the silicon substrate such that a portion of the second surface of the second substrate forms a top of the planar nanofluidic channel.