Patent ID: 8415373

Claim:
A compound according to formula I wherein A is N, CH or CR 1 ; each R 1 is independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, —C(O)—C 1-6 alkyl, —C(O)—C 2-6 alkenyl, —C(O)—C 2-6 alkynyl, —C(O)—O—C 1-6 alkyl, —C(O)—O—C 2-6 alkenyl, —C(O)—O—C 2-6 alkynyl or phenyl, wherein said phenyl, C 1-6 alkyl, C 2-6 alkenyl or C 2-6 alkynyl is optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxyl, C 1-6 haloalkyl, nitro, C 1-6 alkoxy, and NR 2 R 3 ; X is hydrogen, C 1-6 alkyl or —CR a R b —X′, wherein X′ is a monocyclic saturated moiety having 5-6 ring atoms one of which is N and wherein one or two additional ring atom may be a hetero atom selected from N, O and S, which monocyclic ring may be substituted with one or more substituent W, wherein W is selected from the group consisting of C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 haloalkyl or (═O); R a and R b each individually is hydrogen, —CH 3 or halogen; Q is —CH 2 — or —NH—; Y is heteroaryl with 5-6 ring atoms, wherein 1, 2 or 3 ring atoms are selected from O, N or S, or Y is phenyl, wherein said heteroaryl or phenyl may be substituted with one or more substituents selected from the group consisting of halogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl or C 1-6 alkoxy; wherein each of R 2 and R 3 is independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, hydroxyC 1-6 alkyl, or C 1-6 haloalkyl; each of R 4 -R 8 and R 9 -R 12 is independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, halogen, NR 2 R 3 , hydroxy, cyano, nitro, C 1-6 alkoxy, C 1-6 haloalkyl or hydroxyC 1-6 alkyl; or a pharmaceutically acceptable salt thereof.