Patent ID: 7432096

Claim:
A soluble pyrroloquinoline quinone glucose dehydrogenase (sPQQGDH) having the amino acid sequence of wild-type Acinetobacter LMD 79:41 (numbering as shown in SEQ ID NO: 2), wherein compared to the amino acid sequence of wild-type Acinetobacter LMD 79:41 (numbering as shown in SEQ ID NO: 2): a) the following amino acids are exchanged: i) position 21 has a N; ii) position 41 has an S; iii) position 47 has an L; iv) position 121 has a V or an A; v) position 149 has an A; vi) position 213 has an S; vii) position 244 has an I; viii) position 320 has a G; ix) position 391 has an S; x) position 452 has an S; xi) position 474 has an R; and xii) position 480 has a Q; and b) optionally at least one of the following amino acids are also exchanged: i) position 16 has an H; ii) position 18 has an L; iii) position 20 has an F; iv) position 40 has a G; v) position 48 has an I; vi) position 61 has an A; vii) position 111 has a T; viii) position 154 has a D; ix) position 190 has a D; x) position 293 has an A; xi) position 311 has an S; xii) position 314 has an A; xiii) position 324 has an L; xiv) position 333 has an M; xv) position 339 has an S; xvi) position 355 has a G; xvii) position 366 has a D; xviii) position 417 has an N; or xix) position 418 has an A.