Patent ID: 7767645

Claim:
A compound of the formula: wherein R 1 is C 6 -C 14 aryl heterocyclyl C 1 -C 6 alkyl, whose aryl moiety is substituted with one or more groups selected from the group consisting of C 1 -C 6 alkyl, halo, hydroxy, amino, C 1 -C 6 alkoxy, and hydroxy C 1 -C 6 alkyl; R 2 is carboxy C 1 -C 6 alkyl, carboxy C 1 -C 6 alkylamino, oxalylamino, carboxy C 1 -C 6 alkoxy, dicarboxy C 1 -C 6 alkyl, dicarboxy C 1 -C 6 alkyloxy, dicarboxyhalo C 1 -C 6 alkyl, dicarboxyhalo C 1 -C 6 alkyloxy, RSO 2 NH- wherein R is C 1 -C 6 alkyl, halo C 1 -C 6 alkyl, C 6 -C 14 aryl, C 6 -C 14 aryl C 1 -C 6 alkyl, or trifluoro C 1 -C 6 alkyl, phosphono, phosphono C 1 -C 6 alkyl, phosphonohalo C 1 -C 6 alkyl, C 6 -C 14 aryl C 1 -C 6 alkyl phosphino C 1 -C 6 alkyl, C 1 -C 6 alkyl phosphino C 1 -C 6 alkyl, phosphoryl, phosphoryl C 1 -C 6 alkyl, phosphoryl C 1 -C 6 alkoxy, C 6 -C 14 aryl, or C 6 -C 14 aryl C 1 -C 6 alkyl, wherein the aryl and alkyl moieties are optionally substituted with a substituent selected from the group consisting of halo, hydroxy, carboxyl, amino, amino C 1 -C 6 alkyl, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, and keto; R 3 is hydrogen, azido, amino, carboxy C 1 -C 6 alkyl, C 1 -C 6 alkoxycarbonyl C 1 -C 6 alkyl, aminocarbonyl C 1 -C 6 alkyl, or C 1 -C 6 alkylcarbonylamino, wherein the alkyl portion of R 3 are optionally substituted with a substituent selected from the group consisting of halo, hydroxy, carboxyl, amino, amino C 1 -C 6 alkyl, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, and keto; R 4 and R 5 , are independently selected from the group consisting of hydrogen, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, and heterocyclyl, or R 4 and R 5 together form a C 3 -C 8 cycloalkyl or heterocyclyl; and R 6 is a linker; said heterocyclyl is a 4-7 membered ring comprising at least one hetero atom selected from the group consisting of O, N, and S; or a pharmaceutically acceptable salt thereof.