Patent ID: 8492333

Claim:
An isolated peptide comprising one or more amino acid sequence selected from the group consisting of: NFNWGRVVALFYFASKLVLKALXTKV (SEQ ID NO: 3), wherein the X amino acid residue at position 23 of SEQ ID NO: 3 is a threonine, a tyrosine, a non-natural H-bond donor residue or a non-natural H-bond acceptor residue; NFNWGRVVALFYFASKLVLKALXTXV (SEQ ID NO: 4), wherein the X amino acid residue at position 23 of SEQ ID NO: 4 is a lysine, an arginine, an asparagine, a glutamine or a basic residue, and wherein the X amino acid residue at position residue 25 of SEQ ID NO: 4 is a cysteine or a thiol residue; WGRVVALFYFASKLVLKALXTKV (SEQ ID NO: 6), wherein the X amino acid residue at position 20 of SEQ ID NO: 6 is a threonine, a tyrosine, a non-natural H-bond donor residue or a non-natural H-bond acceptor residue; RVVALFYFASKLVLKALXTKV (SEQ ID NO: 8), wherein the X amino acid residue at position 18 of SEQ ID NO: 8 is a threonine, a tyrosine, a non-natural H-bond donor residue or a non-natural H-bond acceptor residue; ALFYFASKLVLKALXTKV (SEQ ID NO: 10), wherein the X amino acid residue at position 15 of SEQ ID NO: 10 is a threonine, a tyrosine, a non-natural H-bond donor residue or a non-natural H-bond acceptor residue; TWQTVTIFVAXVLTASLTIWKK (SEQ ID NO: 11), wherein the X amino acid residue at position 11 of SEQ ID NO: 11 is a lysine, an arginine, an asparagine, a glutamine or a basic residue; and TVTIFVAXVLTASLTIWKK (SEQ ID NO: 13), wherein the X amino acid residue at position 8 of SEQ ID NO: 13 is a lysine, an arginine, an asparagine, a glutamine or a basic residue, and wherein said peptide induces antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity.