Patent ID: 7241760

Claim:
A compound of formula I wherein R 1 is selected from the group consisting of halogen, lower alkyl, lower alkoxy, CF 3 , CF 2 H, OCF 3 , OCF 2 H, and cyano; R 2 is lower alkyl; R 3 is selected from heteroaryl, and heteroaryl substituted by one, two or three substituents, selected from the group consisting of halogen, lower alkyl, cycloalkyl, lower alkyl-halogen, cyano, lower alkoxy, NR′R″, 1-morpholinyl, 1-pyrrolidinyl, 1-pyrrolidinyl substituted by —OR or CH 2 OR, piperidinyl, piperidinyl substituted by —OR or CH 2 OR, thiomorpholinyl, 1-oxo-thiomorpholinyl, 1,1-dioxo-thiomorpholinyl, piperazinyl, and piperazinyl substituted by a substituent selected from lower alkyl, cycloalkyl and CH 2 -cycloalkyl; R is selected from the group consisting of hydrogen, lower alkyl, cycloalkyl and CH 2 -cycloalkyl; R′ and R″ are each independently selected from the group consisting of hydrogen, lower alkyl, cycloalkyl, CH 2 -cycloalkyl, —OR and CH 2 —OR; R 4 is selected from the group consisting of hydrogen, C(O)H, and CH 2 R 5 ; and R 5 is selected from the group consisting of hydrogen, OH, C 1 –C 6 -alkyl, and C 3 –C 12 -cycloalkyl; or a pharmaceutically acceptable salt thereof.