Patent ID: 7276228

Claim:
A method for treating a hematological disorder of a patient comprising: administering to the patient suffering from the hematological disorder a therapeutically effective amount of a DNA methylation inhibitor selected from the group consisting of decitabine and 5-azacytidine at a dose ranging from 1 to 50 mg/M 2 per day, in combination with an effective amount of histone deacetylase inhibitor selected from the group consisting of trichostatin A, suberoylanilide hydroxamic acid, oxamflatin, suberic bishydroxamic acid, m-carboxy-cinnamic acid bishydroxamic acid, pyroxamide, trapoxin A, apicidin, depsipeptide, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide, butyric acid, phenylbutyrate and arginine butyrate.