Patent ID: 7825135

Claim:
A compound of formula Ic: or a pharmaceutically acceptable salt thereof, wherein: R 1 is selected from the group consisting of: (1) hydrogen, (2) C 1-3 alkyl, (3) fluoro, (4) —CF 3 , (5) -morpholinyl, and (6) —O—C 1-3 alkyl; R 2 is phenyl, which is substituted with R 2a , R 2b and R 2c , R 2a , R 2b and R 2c are independently selected from the group consisting of: (1) hydrogen, (2) halogen, (3) —C 1-6 alkyl, (4) —CF 3 , (5) —OCF 3 , (6) —OCHF 2 , (7) —SCF 3 , (8) —SCHF 2 , and (9) —NH 2 ; R 3 is C 1-6 alkyl, which is unsubstituted or substituted with 1-6 halogen, hydroxyl, —NR 10 R 11 , or heterocycle, which is substituted with R 2a , R 2b and R 2c ; R 4 and R 5 are independently selected from the group consisting of: (1) hydrogen, and (2) C 1-6 alkyl, which is unsubstituted or substituted with halogen or hydroxyl, or R 4 and R 5 taken together form a C 3-6 cycloalkyl ring; and R 10 and R 11 are independently selected from: (a) hydrogen, (b)—C 1-6 alkyl, which is unsubstituted or substituted with hydroxy, 1-6 fluoro or —NR 12 R 13 , where R 12 and R 13 are independently selected from hydrogen and —C 1-6 alkyl, and where R 10 and R 11 may be joined to form an azetidinyl ring, (c) —C 3-6 cycloalkyl, which is unsubstituted or substituted with hydroxy, 1-6 fluoro or —NR 12 R 13 , (d) benzyl and (e) phenyl.