Patent ID: 7285550

Claim:
A compound of the following formula: or a pharmaceutically acceptable salt or N-oxide thereof; wherein A is aryl or heteroaryl; B is N or CR 2 ; each of R 2 and R 3 is independently hydrogen, alkyl, cycloalkyl, cycloalkenyl, aryl, aralkyl, heterocycloalkyl, heterocycloalkenyl, heteroaryl,or heteroaralkyl; each of X 1 and X 2 is independently C 1-6 alkylene, C 2-6 alkenylene, C 2-6 alkynylene, or a bond; L is wherein: each R′ independently, is hydrogen, alkyl, alkenyl, alkynyl, alkoxy, acyl, halo, hydroxy, amino, nitro, oxo, thioxo, cyano, guanadino, amidino, carboxy, sulfo, sulfoxy, mercapto, alkylsulfanyl, alkylsulfinyl, alkylsulfonyl, aminocarbonyl, alkylcarbonylamino, alkylsulfonylamino, alkoxycarbonyl, alkylcarbonyloxy, urea, thiourea, sulfamoyl, sulfamide, carbamoyl, cycloalkyl, cycloalkyloxy, cycloalkylsulfanyl, heterocycloalkyl, heterocycloalkyloxy, heterocycloalkylsulfanyl, aryl, aryloxy, arylsulfanyl, aroyl, heteroaryl, heteroaryloxy, heteroarylsulfanyl, or heteroaroyl; provided that two adjacent R′ groups can join together to form a 4- to 8-membered optionally substituted cyclic moiety; X a is —C(R 2 )(R 3 )—, —S—, —SO—, or —SO 2 —; X b is —C(R 2 )(R 3 )—, —NR 2 —, —O—, —S—, —SO—, or —SO 2 —; each of p, and m, and independently, is 0-3; Y is —C(R 2 )(R 3 )—, —O—, —S—, —SO—, —SO 2 —, —CO—, —CO 2 —, or a bond; and R 1 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, aryl, aralkyl, heterocyclyl, or heterocyclylalkyl; provided that (1) when X 1 is a bond, then X 2 is alkylene and R 1 is heteroaryl.