Patent ID: 7276592

Claim:
A compound comprising a structure of the formula wherein L is a linking moiety; B is a heterocyclic base; R 1 is selected from the group consisting of a protecting group, a label, a solid phase, and —H; R 2 is selected from the group consisting of —H and —OR 6 ; R 3 is selected from the group consisting of a protecting group, a linking moiety covalently coupled to a solid phase, a phosphate, a phosphoramidite, an H-phosphonate, and a triphosphate; R 4 is selected from the group consisting of —H, —OH, alkyl, halogen, —O—R 5 , —S—R 5 , NR 5 R 5a , a label, and a linking moiety covalently coupled to a solid phase; R 5 is selected from the group consisting of —H, a protecting group, a linking moiety covalently coupled to a solid phase, a phosphoramidite, and a H-phosphonate; Y is selected from the group consisting of O, S, NR 5 , CR 5a R 5b , and CR 5a , and the bond between the C-1 atom of the six-membered ring and Y is a single bond When Y is O, S, NR 5 , or CR 5a R 5b and a double bond when Y is CR 5a ; and R 5 is selected from the group consisting of alkyl, alkenyl, alkinyl, aryl, acyl, a protecting group, and —H and R 5a and R 5b are selected front the group consisting of alkyl, alkenyl, alkinyl, aryl, acyl, and —H, with the proviso that when R 1 , R 3 , or R 6 is a solid phase, then the other two residues selected from the group consisting of R 1 , R 2 , and R 6 are not a solid phase.