Patent ID: 7446103

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 and R 2 independently represent halogen, hydroxy, cyano, nitro, oxo, haloC 1-6 alkyl, polyhaloC 1-6 alkyl, haloC 1-6 alkoxy, polyhaloC 1-6 alkoxy, C 1-6 alkyl, C 1-6 alkoxy, arylC 1-6 alkoxy, C 1-6 alkylthio, C 1-6 alkoxyC 1-6 alkyl, C 3-7 cycloalkylC 1-6 alkoxy, C 1-6 alkanoyl, C 1-6 alkoxycarbonyl, aryl, heteroaryl, heterocyclyl with 4-7 membered monocyclic saturated or partially unsaturated aliphatic ring containing 1 to 3 heteroatoms selected from oxygen or nitrogen, arylC 1-6 alkyl, heteroarylC 1-6 alkyl, heterocyclylC 1-6 alkyl, C 1-6 alkylsulfonyl, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyloxy, C 1-6 alkylsulfonylC 1-6 alkyl, arylsulfonyl, arylsulfonyloxy, arylsulfonylC 1-6 alkyl, aryloxy, —CO-aryl, —CO-heterocyclyl, —CO-heteroaryl, C 1-6 alkylsulfonamidoC 1-6 alkyl, C 1-6 alkylamidoC 1-6 alkyl, arylsulfonamido, arylaminosulfonyl, arylsulfonamidoC 1-6 alkyl, arylcarboxamidoC 1-6 alkyl, aroylC 1-6 alkyl, arylC 1-6 alkanoyl, or a group NR 15 R 16 , —NR 15 CO-aryl, —NR 15 CO-heterocyclyl, —NR 15 CO-heteroaryl, —CONR 15 R 1-6 , —NR 15 COR 16 , —NR 15 SO 2 R 16 or —SO 2 NR 15 R 16, wherein R 15 and R 16 independently represent hydrogen or C 1-6 alkyl; wherein said aryl, heteroaryl and heterocyclyl groups of R 1 and R 2 may be optionally substituted by one or more substituents which may be the same or different and which are selected from halogen, C 1-6 alkyl, C 1-6 alkoxy, oxo, CF 3 , OCF 3 , CN, C 1-6 alkanoyl, C 1-6 alkylsulfonyl, C 1-6 alkylsulfonyloxy, C 1-6 alkylamido or C 1-6 alkylsulfonamido; a and b independently represent 0, 1 or 2, such that a and b cannot both represent 0; is a single or double bond; R 3 represents halogen, C 1-6 alkyl, C 1-6 alkoxy, cyano, amino or trifluoromethyl; m and n independently represent 0, 1 or 2; p represents an integer from 0 to 3, such that when p is an integer greater than 1 two R 1 groups may instead be linked to form a heterocyclyl group; R 4 represents —(CH 2 ) q —NR 11 R 12 or a group of formula (i): wherein q is 2, 3 or 4; R 11 and R 12 independently represent C 1-6 alkyl or together with the nitrogen atom to which they are attached represent an N-linked heterocyclic group optionally substituted by one or two R 17 groups; R 13 represents hydrogen, C 1-6 alkyl, C 3-8 cycloalkyl, —C 1-6 alkyl-aryl or heterocyclyl; R 14 and R 17 independently represent halogen, C 1-6 alkyl, haloC 1-6 alkyl, OH, diC 1-6 alkylamino or C 1-6 alkoxy; f and k independently represent 0, 1 or 2; g is 0, 1 or 2 and h is 0, 1, 2 or 3, such that g and h cannot both be 0; or solvates thereof.