Patent ID: 7053204

Claim:
An isolated nucleic acid comprising a nucleotide sequence selected from the group consisting of: (a) the nucleotide sequence set forth in SEQ ID NO:2; (b) a nucleotide sequence encoding the amino acid sequence set forth in SEQ ID NO:3; and, (c) a nucleotide sequence which specifically hybridizes under stringent conditions, comprising a 0.2×SSC wash at 65° C. for 15 minutes, to either strand of a denatured, double-stranded nucleic acid having a nucleotide sequence set forth in SEQ ID NO:2; wherein expression of the nucleotide sequence in an ascomycete host cell results in the increased production of a polypeptide capable of regulating a gene cluster specifying the production of at least one secondary metabolite selected from the group consisting of a polyketide, a non-ribosomal protein and a hyphal pigment.