Patent ID: 6864373

Claim:
A process for preparing a celecoxib-crystallization inhibitor composite wherein at least a detectable portion of the celecoxib is in amorphous form, said process comprising the steps of (a) dissolving celecoxib in at least one pharmaceutically acceptable solvent for the celecoxib to form a first solution; (b) dissolving at least one crystallization inhibitor in at least one pharmaceutically acceptable solvent for the crystallization inhibitor to form a second solution; (c) adding the first solution to the second solution at a rate of not more than about 20%, by volume, of the first solution, per second, to form a mixture; (d) equilibrating the mixture for a period of time effective to result in precipitation of a celecoxib-crystallization inhibitor composite from the mixture; and (e) separating the precipitated celecoxib-crystallization inhibitor composite from the mixture.