Patent ID: 8395037

Claim:
A method for treating cartilage degeneration, comprising intraarticularly administering in a subject in need thereof a pharmaceutically effective amount of at least one active ingredient selected from the group consisting of an un-substituted fullerene, a clathrate fullerene, a heterofullerene, a norfullerene, a homofullerene, a secofullerene, a fullerene polymer, a chemically modified fullerene selected from the group consisting of a hydrogenated fullerene, a fullerene substituted with a hydroxyl group, an amino group, or a carboxyl group, and a fullerene conjugated with polyethylene glycol or hyaluronic acid, and a salt thereof, wherein the dosage is 0.1 micro Molar to 100 micro Molar per affected part, and wherein the active ingredient induces cartilage matrix production.