Patent ID: 7070922

Claim:
A process for producing a biomolecular monolayer on a surface, comprising: reacting homobifunctional polyethylene glycol (PEG) N-hydroxy succinimide (NHS) with aminopropyl trimethoxysilane at between 46 and 50 degrees Celsius for between 30 and 60 minutes to form a NHS-PEG-triethoxysilane reagent, wherein the aminopropyl trimethoxysilane comprises a first functional group for forming a covalent bond to a surface group and a second functional group for forming a covalent bond with the homobifunctional PEG NHS; exposing the surface to the NHS-PEG-triethoxysilane reagent to form the covalent bond between the surface and first functional groups and obtain a self-assembled monolayer; and thereafter reacting the monolayer with biomolecules.