Patent ID: 8097620

Claim:
A composition of matter, comprising at least one compound of Formula I: a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer; or a mixture of any of the foregoing, wherein: J is CR 6 ; K is N; L is CR 6 ; M is N n is 1; R 1 and R 2 are H; X is selected from —NR a —, wherein R a is H; R 3 is selected from OH, SH, NH 2 , lower alkyl, substituted lower alkyl, lower alkoxy, substituted lower alkoxy, or sulfanyl; R 4 is selected from H, OH, lower alkoxy, SH, NH 2 , NHSO 2 R 7 , or sulfonyl; R 5 is selected from H, lower alkyl, or substituted lower alkyl; each R 6 is independently selected from H, F, Cl, Br, I, alkyl, substituted alkyl, haloalkyl, perhaloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, NR d R e , C(O)R 7 , C(O)OR 8 , OR 8 , SR 8 , SO 2 R 8 , CN, NO 2 , aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroaryl, substituted heteroaryl, heteroarylalkyl, substituted heteroarylalkyl, heterocyclyl, substituted heterocyclyl, heterocyclylalkyl, substituted heterocyclylalkyl, or —Y—R 9 , wherein: Y is selected from —N(R 10 )—Z— or —Z—N(R 10 )—; Z is selected from C(O), SO 2 , alkylene, substituted alkylene, alkenylene, substituted alkenylene, alkynylene, or substituted alkynylene; R 7 is selected from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl; R 8 is selected from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, or substituted alkynyl; R 9 is selected from H, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl; R 10 is selected from H, lower alkyl, or substituted lower alkyl; and R d and R e are independently selected from H, lower alkyl, substituted lower alkyl, lower haloalkyl, or substituted lower haloalkyl, or R d and R e can join together to form a 3 to 6 membered ring or a substituted 3 to 6 membered ring.