Patent ID: 7985860

Claim:
A process for preparing an oxazole compound of Formula ID wherein R 1 is a haloalkyl; R 2 , R 4 are alkyl; R 5 is selected from hydrogen, methyl alkyl, hydroxyalkyl, alkoxyalkyl, mercaptoalkyl, —CH 2 F, —CHF 2 , —CF 3 , —C(O)O-alkyl and —C(O)NR 43a R 44a , where R 43a and R 44a are independently selected for each occurrence from the group of H, alkyl, and a nitrogen protecting group; and R 6 is selected from acid labile amino protecting groups; the process comprising: (a) providing a solution comprising the compound of Formula IDa, wherein, R 1 , R 2 and R 4 are defined above; R 3 is selected from hydrogen and alkyl; and X is selected from oxygen and sulfur; (b) reacting the solution provided in Step “a” with an alkali metal amide base; and (c) reacting the mixture provided in Step “b” with a compound of Formula IDb, wherein R 5 and R 6 are as defined above; and R 7 represents an activated acid moiety.