Patent ID: 7371385

Claim:
A method of ameliorating multiple sclerosis in a human subject, comprising administering a dose of estrogen to said human subject sufficient to raise the serum concentration of estrogen in said human to within the range from 30 pg/ml to 1000 pg/ml and administering a therapeutically effective amount of a T cell receptor peptide comprising a human Vβ2, Vβ5.1, Vβ5.2, Vβ6.1, Vβ6.5, Vβ7, or a Vβ13 T cell receptor peptide CDR2 region, or an analog of a Vβ5.2 T cell receptor peptide comprising the amino acid sequence set forth as SEQ ID NO: 3, to said human subject thereby ameliorating multiple sclerosis in said human subject.