Patent ID: 7531534

Claim:
A compound according to formula Ia wherein: R 1 is halogen, C 1-3 alkyl, COR 5 , CH 2 COR 5 , CN or CH 2 CN; R 2 is C 1-6 alkyl, C 3-7 cycloalkyl, C 3-7 cycloalkyl-C 1-3 alkyl, phenyl-C 1-3 alkyl, NR a R b or phenyl wherein said phenyl rings are optionally substituted with 1 to 3 groups independently selected in each occurrence from the group consisting of C 1-6 alkyl, C 1-6 alkoxy, halogen, NR a R b and cyano; R 3 is C 1-6 alkyl, C 3-7 cycloalkyl-C 1-3 alkyl, phenyl-C 1-3 alkyl wherein said phenyl is optionally substituted with 1 to 3 groups independently selected in each occurrence from the group consisting of C 1-6 alkyl, C 1-6 alkoxy, halogen, NR a R b , nitro and cyano, or pyridinyl-methyl said pyridinyl optionally substituted with halogen; R 4 is C 1-6 alkyl or C 3-7 cycloalkyl; R 5 is OH, C 1-6 alkoxy, NR c R d ; R a and R b (i) taken independently in each occurrence are hydrogen or C 1-6 alkyl or (ii) taken together are (CH 2 ) n wherein n is 4-6 or (CH 2 ) 2 X(CH 2 ) 2 wherein X is O, S, NR c ; R c and R d are independently hydrogen or C 1-6 alkyl; or, pharmaceutically acceptable salts thereof.