Patent ID: 7947701

Claim:
A compound corresponding to formula (I): in which: A represents a residue of a molecule with antimalarial activity and/or a residue that facilitates the bioavailability wherein A represents an aminoquinoline of formula (IIb): in which , B 1 is N and B 2 is ═CH—; R and R′, which may be identical or different, each represent one or more substituents occupying distinct positions on the rings to which they are attached, chosen from hydrogen or halogen atoms and the groups —OH, —CF 3 , aryl, heteroaryl, alkyl or —O-alkyl, —NO 2 or —N(Ra,Rb), where Ra and Rb, which may be identical or different, represent hydrogen atoms or alkyl groups containing from 1 to 5 carbon atoms and being linear or branched; at least one of R or R′ being different from a hydrogen atom; R4 represents a hydrogen atom or a linear or branched C1 to C5 alkyl radical, in the form of a base or of an addition salt with an acid; p represents 1, p′ and p″ represents 0 or 1, Y 1 and Y 2 , which may be identical or different, represent a linear C 1 to C 6 alkylene chain optionally comprising one or more carbonyl, thiocarbonyl ether or thioether radicals, U represents an amine, amide, thioamide, sulphonyl, sulphonate, sulphonamide, carbonyl, thiocarbonyl, carboxyl, thiocarboxyl, ether or thioether radical, Z 1 and Z 2 , which may be identical or different, represent a saturated linear C 1 to C 4 alkylene radical, and Cj represens carbon, R 1 and R 2 , which may be identical or different, represent a hydrogen atom or a functional group capable of increasing the water-solubility of the dual molecule, R x and R y together form a cyclic peroxide wherein, R x and R y together form a cyclic peroxide corresponding to formula (XI), said cyclic peroxide being substituted with 1 to 4 groups R 3 , which may be identical or different from one another, occupying any positions on the carbon atoms of the peroxide ring and being chosen from the following atoms and groups: hydrogen, halogen, —OH, —CF 3 , —NO 2 , aryl or heteroaryl, (C 3 -C 8 ) cycloalkyl, alkyl or —O-alkyl, said alkyl groups containing from 1 to 10 carbon atoms and being linear or branched, at least one of the groups R 3 being different from a hydrogen atom, in the form of a base or of an addition salt with an acid.