Patent ID: 7091202

Claim:
A compound of Formula I wherein: Q is CH or N; X is a bond, methylene, ethylene, or propylene; R 1 is hydrogen, C 1-6 alkyl, C 3-7 cycloalkyl, CH 2 Ar 1 , CH 2 CH 2 Ar 1 , CH(CH 3 )Ar 1 , CH 2 CH(CH 3 )Ar 1 , CH(CH 2 OH)CH 2 Ar 1 , CH 2 CH 2 CH 2 Ar 1 , CH 2 CH 2 OAr 1 , CH 2 CH 2 SAr 1 , CH 2 CH 2 N(R 7 )Ar 1 , CH 2 CH 2 CH 2 CH 2 Ar 1 , CH 2 CH 2 CH 2 CH 2 CH 2 Ar 1 , or CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 Ar 1 wherein the C 1-6 alkyl group is unsubstituted or substituted with 1–2 moieties selected from the group consisting of OR 7 , CO 2 R 7 , N(R 7 )(R 7 ), CON(R 7 )(R 7 ), N(R 7 )COR 7 , and R 8 ; R 2 is hydrogen or C 1-6 alkyl; or NR 1 R 2 taken together are R 3 is hydrogen, C 1-6 alkyl, C 3-7 cycloalkyl, CH 2 Ar 1 , CH 2 CH 2 Ar 1 , CH(CH 3 )Ar 1 , CH 2 CH(CH 3 )Ar 1 , CH(CH 2 OH)CH 2 Ar 1 , CH 2 CH 2 CH 2 Ar 1 , CH 2 CH 2 OAr 1 , CH 2 CH 2 SAr 1 , CH 2 CH 2 N(R 7 )Ar 1 , CH 2 CH 2 CH 2 CH 2 Ar 1 , CH 2 CH 2 CH 2 CH 2 CH 2 Ar 1 , CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 Ar 1 , Ar 2 , CH 2 Ar 2 , CH 2 CH 2 Ar 2 , or CH(CH 3 )Ar 2 , wherein the C 1-6 alkyl group is unsubstituted or substituted with 1–2 moieties selected from the group consisting of OR 7 , CO 2 R 7 , N(R 7 )(R 7 ), CON(R 7 )(R 7 ), N(R 7 )COR 7 , and R 8 ; R 4 is hydrogen or C 1-6 alkyl; or N(R 3 )(R 4 ) taken together are R 5 and R 6 are independently hydrogen, halo, C 1-6 alkyl, trifluoromethyl, cyano, OR 7 , or N(R 7 )(R 7 ); R 7 is independently hydrogen or C 1-6 alkyl; R 8 is a heterocycle selected from the group consisting of tetrahydrofuranyl, pyrrolidinyl, piperidinyl, and benzopyrrolidinyl and is unsubstituted or substituted with 1 substituent selected from the group consisting of oxo, C 1-6 alkyl, hydroxymethyl, benzyl, and CO 2 R 7 ; R 9 is hydrogen, C 1-6 alkyl, CO 2 R 7 , or CON(R 7 )(R 7 ); R 10 is hydrogen or phenyl; R 11 is hydrogen, C 1-6 alkyl, or C 1-6 hydroxyalkyl; R 12 is hydrogen, C 1-6 alkyl, or COR 7 ; Ar 1 is phenyl, naphthyl, pyridinyl or benzodioxolanyl and is unsubstituted or substituted with 1–2 moieties selected from the group consisting of halo, C 1-6 alkyl, trifluoromethyl, cyano, pyridinyloxy, OR 7 , N(R 1 )(R 2 ), or Ar 2 ; and Ar 2 is pyridinyl, pyrimidinyl, pyridizinyl, or triazinyl; or a pharmaceutically acceptable salt thereof.