Patent ID: 7837654

Claim:
A needle insertable in a target cell tissue within a human or animal, comprising: a microneedle having a manipulative end maintained exterior of target cell tissue and having a fluid flow conduit extended through an interior of said microneedle, said fluid flow conduit in communication with means for fluid flow positioned exterior of the human or animal, said microneedle having an insertion end sized for positioning in or adjacent of target cell tissue and having a needle body having an outside diameter in a micron size range, said needle body joining said manipulative and insertion ends; and said fluid flow conduit including a plurality of microtubes extended in a compact bundled configuration through said needle body, said plurality of microtubes having respective distal ends grouped proximally interior of said insertion end and having respective microtube proximal ends extended from said manipulative end, including a first microtube proximal end and a second microtube proximal end separately in communication with means for fluid flow, thereby said first microtube providing a conduit for a microliter volume of a first fluid flow separate from and within said interior of said microneedle, said first fluid flow further separate from said second microtube providing a second conduit for a second microliter volume of a second fluid flow between a distal end of respective first and second microtube proximal ends extended from said manipulative end in communication with means for fluid flow; whereby said insertion end is positionable in or adjacent of target cell tissue with said plurality of microtubes distal ends positioned in or adjacent of target cell tissue, thereby providing cell tissue sampling for evaluation of target cell tissue parameters by separate fluid flow transfer of first and second fluid flow between said microneedle insertion end and said manipulative end, and further providing repetitive and coordinated delivery of first and second treatment fluid fluids into or adjacent of target cell tissue by transfer of treatment fluid fluids from means for fluid flow and through said first and second microtube of said plurality of microtubes without removal or reposition of said first and second microtube within said needle body.