Patent ID: 7309584

Claim:
An isolated nucleic acid molecule comprising a nucleotide sequence encoding human P-glycoprotein and having an asparagine residue at position 186, a phenylalanine residue at position 56, a phenylalanine residue at positions 190 and 197, a tryptophan residue at position 763, a glutamic acid residue at position 844, a lysine residue at positions 634 and 636, a lysine residue at positions 643, 647, and 652, a lysine residue at positions 634, 636, 643, 647, and 652, a phenylalanine residue at position 190, a phenylalanine residue at position 197, a lysine residue at position 634, a lysine residue at position 636, a lysine residue at position 643, a lysine residue at position 647, or a lysine residue at position 652 of the human P-glycoprotein amino acid sequence.