Patent ID: 8702983

Claim:
An axial flow chromatography column which is pre-packed and adapted to be connected to a chromatography system, said chromatography column comprising: a housing comprising a side wall; axially spaced first and second end units positioned opposed to each other are separated by said side wall; a first filter which is adjacent to said first end unit and a second filter which is adjacent to said second end unit wherein said first and second filters together with the side wall define an enclosed bed space for containing a bed of particulate medium therein; the first end unit including a first port which is in fluid communication with said enclosed bed space for adding a liquid to or removing a liquid from the bed space; a second port comprising a passageway which extends through the second end unit and which is in fluid communication with the enclosed bed space for adding a liquid to or removing a liquid from the bed space and wherein said second port does not comprise a purge valve; and said first port and said second port are at essentially the same level or elevation above the level of the bed space on said chromatography column; and wherein the second port is in direct fluid communication with the bed space by means of a hollow member connected to the passageway in the second end unit.