Patent ID: 7591806

Claim:
A method of making a microfabricated device for delivery of an active agent comprising: performing a first isotropic etch to define microneedle tips, microblade edge, or microknife edge of the device, performing a second anisotropic Bosch etch to define microneedle shaft, microblade body, or microknife body of the device, thereby forming the device, and forming the device, wherein the microfabricated device comprises a structure formed of a material selected from the group consisting of metals, ceramics, silicon, glass, polymers, and combinations thereof, wherein the structure is selected from the group consisting of solid microneedles, solid microblades, solid microknives, and a combination thereof, wherein the microneedles, microblades, or microknives have and aspect ration of about 10:1 or higher.