Patent ID: 7868032

Claim:
A compound having prostamide receptor antagonist activity represented by the general formula I: wherein m is an integer of from 1 to 3; A is an aryl or heteroaryl radical having from 6 to 14 carbon atoms, wherein said heteroaryl may be substituted with one or more oxygen, sulfur or nitrogen in the heteroaryl ring and heteroatom substituted derivatives thereof; n is 0 or an integer of from 1 to 4; R is OCH 2 CONR 3 R 4 ; R 1 and R 2 are independently selected from the group consisting of H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 7 cycloalkyl, C 4 -C 12 alkylcycloalkyl, C 6 -C 10 aryl, C 7 -C 12 alkyl aryl radicals and heteroatom-substituted derivatives thereof, wherein one or more of the hydrogen or carbon atoms in said radicals is replaced with a halogen, oxygen, nitrogen or sulfur-containing radical; R 3 and R 4 are selected from the group consisting of H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 7 cycloalkyl, C 4 -C 12 alkylcycloalkyl, C 6 -C 10 aryl, C 7 -C 12 alkyl aryl radicals and heteroatom-substituted derivatives thereof, wherein one or more of the hydrogen or carbon atoms in said radicals is replaced with a halogen, oxygen, nitrogen or sulfur-containing radical and pharmaceutically acceptable salts thereof.