Patent ID: 7772439

Claim:
An amino or thiol linker building block comprising: a) a linker chain; b) a phosphoramidite moiety bonded to the linker chain having the structure wherein, R11 and R12 are independent alkyl-groups containing one to four C-atoms; R13 is a methyl-group or cyanoethyl-group; and R14 is said linker chain; c) a protecting group bonded to the linker chain; and d) a reporter group bonded to the protecting group; wherein said linker chain (R14) is an alkyl-chain; wherein said protecting group has the structure wherein, X is NH or S; R1 and R2 are independently halogen, an alkyl-, or an alkyloxy-group containing one to four C-atoms, LC is the point of attachment to the linker chain, RE is the point of attachment to the reporter group, and wherein Y is selected from the group comprising: wherein R3 and R4 are independently halogen, hydrogen, or an alkyl-group comprising one to four C-atoms, or an alkyloxy-group comprising one to four C-atoms; wherein R5 is hydrogen or an alkyl-group comprising one to four C-atoms: wherein R6, R7, RS, and R9 are independently halogen, hydrogen or alkyl-groups comprising one to four C-atoms, or an alkyloxy-group comprising one to four C-atoms; and wherein R10 is hydrogen or an alkyl-group comprising one to four C-atoms.