Patent ID: 7456165

Claim:
A compound of formula I wherein: R 1 is CO 2 R 5 or CONR 6 R 7 ; R 2 is furanyl, pyrrolyl, thienyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, oxadiazolyl, triazolyl, or tetrazolyl, and is substituted with 0-2 substituents selected from oxo, amino, alkylamino, dialkylamino, alkyl, (cycloalkyl)alkyl, hydroxyalkyl, (tetrahydrofuranyl)alkyl, (tetrahydropyranyl)alkyl, (CO 2 R 5 )alkyl, (CON(R 5 ) 2 )alkyl, (COR 9 )alkyl, (alkylsulfonyl)alkyl, and ((R 9 )alkyl)CON(R 5 ); R 3 is C 5-7 cycloalkyl; R 4 is hydrogen, halo, hydroxy, alkyl, or alkoxy; R 5 is hydrogen, alkyl, or cycloalkyl; R 6 is hydrogen, alkyl, cycloalkyl, alkoxy, or SO 2 R 8 ; R 7 is hydrogen, alkyl, or cycloalkyl; or NR 6 R 7 taken together is pyrrolidinyl, piperidinyl, piperazinyl, N-alkylpiperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl; R 8 is alkyl, haloalkyl, cycloalkyl, amino, alkylamino, dialkylamino, or phenyl; or R 8 is pyrrolidinyl, piperidinyl, piperazinyl, N-alkylpiperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl; R 9 is pyrrolidinyl, piperidinyl, piperazinyl, N-alkylpiperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl; and (a) is a single bond or a double bond, (b) is a single bond or a double bond, provided that at least one of (a) and (b) is a single bond; or a pharmaceutically acceptable salt thereof.