Patent ID: 7718600

Claim:
A compound of formula I wherein R 1 is methyl, ethyl, n-propyl, isopropyl, or ethenyl; R 1a is H or methyl; X is —O—, —S—, CH 2 —, or —NH—, and J is —CH— or —N—, provided that when J is —N—, X is —CH 2 — or —NH—; Y is H, methyl, ethyl, n-propyl, or isopropyl; R 2 is: R 3 , R 4 and R 5 are each independently H, methyl, ethyl, n-propyl, isopropyl, halo, cyano, —(CH 2 ) p —C(═O)OH, —(CH 2 ) p —C(═O)O-alkyl, or C(═O)NH 2 ; n and p are each independently the integer 0, 1, 2, or 3, and the sum of n plus p is the integer 2 or 3; provided that at least one of R 3 , R 4 and R 5 is H, methyl, ethyl, n-propyl, isopropyl, halo or cyano; provided that when one or more of R 3 and R 5 is isopropyl, R 4 is other than isopropyl; provided that when R 4 is isopropyl, R 3 and R 5 are each independently other than isopropyl; or a pharmaceutically acceptable salt thereof, wherein said compound binds to an Inhibitor of Apoptosis Protein (TAP).