Patent ID: 7982011

Claim:
An antibody that specifically binds CD22, said anti-CD22 antibody having a variable light (VL) chain comprising three complementarity determining regions (CDRs), and a variable heavy (VH) chain comprising three CDRs, wherein (i) said VL chain CDR1 has the sequence of SEQ ID NO:7, wherein positions 4-5 of SEQ ID NO:7 have an amino acid sequence selected from the group consisting of HG, GR, RG and AR, (ii) said VL CDR2 has the sequence of SEQ ID NO:11, (iii) said VL CDR3 has the sequence of SEQ ID NO:12, (iv) said VH CDR1 has the sequence of SEQ ID NO:13, (v) said VH CDR2 has the sequence of SEQ ID NO:14, and (vi) said VH CDR3 has the sequence of SEQ ID NO:16, wherein positions 8-10 of SEQ ID NO:16 have an amino acid sequence selected from the group consisting of THW, YNW, TTW and STY.