Patent ID: 8906423

Claim:
A process for obtaining an active constituent from a plant extract of Uncaria tomentosa , the process comprising: (a) preparing a material from portions of Uncaria tomentosa plants of a pentacyclic alkaloids chemotype, standardized in minimum 0.3% of total oxydole alkaloids calculated as mitraphylline, and a granulometry profile with a minimum of 80% of the particles smaller than 120 mesh; (b) mixing the prepared material with a 70% ethanol aqueous solution to create a slurry; (c) performing agitation of the slurry at room temperature for a period of time sufficient for extracting the active constituent; (d) separating a liquid phase from the slurry, the liquid phase containing the active constituent; (e) filtering remaining solid or semi-solid particulate matter from the liquid phase, the filtering resulting in filtered particulate matter, and (f) obtaining a final product containing the active constituent having a content of total pentacyclic oxindole alkaloids calculated as mitraphylline of from 660 μg/g to 900 μg/g.