Patent ID: 8632780

Claim:
A modified human complement C3 protein consisting of SEQ ID NO:2 with a substitution of a portion of a human C3 protein (SEQ ID NO:2) with a corresponding portion of a Cobra Venom Factor (CVF) protein (SEQ ID NO:4), wherein the substitution is selected from the group consisting of: amino acids 1550-1663 of human C3 (SEQ ID NO:2) substituted with amino acids 1529-1642 of CVF (SEQ ID NO:4), amino acids 1504-1663 of human C3 (SEQ ID NO:2) substituted with amino acids 1484-1642 of CVF (SEQ ID NO:4), amino acids 1348-1663 of human C3 (SEQ ID NO:2) substituted with amino acids 1330-1642 of CVF (SEQ ID NO:4), amino acids 1550-1617 of human C3 (SEQ ID NO:2) substituted with amino acids 1529-1596 of CVF (SEQ ID NO:4), amino acids 1504-1617 of human C3 (SEQ ID NO:2) substituted with amino acids 1484-1642 of CVF (SEQ ID NO:4), and amino acids 1496-1663 of human C3 (SEQ ID NO:2) substituted with amino acids 1475-1642 of CVF (SEQ ID NO:4).