Patent ID: 7776883

Claim:
A compound of the following formula (I), or a tautomer or pharmaceutically acceptable salt thereof: wherein R 1 is selected from —H, —C 1-6 alkyl, or —C 1-6 alkyl substituted with R 7 ; Z is selected from —C(O)OR 2 or —C(O)CH 2 C(O)X; X is selected from: (a) a 5 or 6-membered aromatic or heteroaromatic ring, containing 0, 1, 2, 3 or 4 heteroatoms selected from oxygen, nitrogen and sulfur, unsubstituted or independently substituted on a nitrogen or carbon atom by at least one substituent selected from halogen, C 1-6 alkyl, or phenyl, or (b)—C(O)OR 2 ; R 2 is selected from —H or —C 1-6 alkyl; R 3 , R 4 , R 5 and R 6 are each independently selected from —H, —halogen, —C 1-6 alkyloxy—, —N(R 8 )(R 9 ), —C(O)CH 3 , —C(O)CH 2 C(O)X, —S(O) n —R 10 wherein n is independently selected from 0, 1 and 2, heteroalkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl; R 7 independently selected from heteroalkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl; each R 8 and R 9 is independently selected from —H or —C 1-2 alkyl; and each R 10 is independently selected from —C 1-6 alkyl, pyridyl, or phenyl, wherein the phenyl is unsubstituted or substituted on a carbon atom by least one substituent selected from halogen, —CH 3 , —OR 2 , or —NO 2 ; provided that if Z is —C(O)OR 2 then at least one of R 3 , R 4 , R 5 or R 6 is —C(O)CH 2 C(O)X.