Patent ID: 8158655

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: R 1 and R 1′ are independently selected from the group consisting of: (1) hydrogen, (2) halogen, (3) nitro, (4) cyano, (5) amino, (6) C 1-6 alkyl, (7) heteroalkyl, (8) C 3-7 cycloalkyl, (9) C 2-6 alkenyl, (10) C 2-6 alkynyl, (11) hydroxy, (12) C 1-6 alkoxy, (13) —NR′R″ or —(C 0-6 alkylene)-NR′R″, in which R′ and R″ are independently selected from the group consisting of hydrogen, C 1-6 alkyl, heteroalkyl, formyl, C 1-6 alkylcarbonyl, optionally substituted C 3-7 cycloalkylcarbonyl, optionally substituted arylcarbonyl, optionally substituted heteroarylcarbonyl, optionally substituted heterocyclylcarbonyl, C 1-6 alkylsulfonyl, optionally substituted C 3-7 cycloalkylsulfonyl, optionally substituted arylsulfonyl, optionally substituted heteroarylsulfonyl, and optionally substituted heterocyclylsulfonyl, and (14) —(C 0-6 alkylene)-OR′, in which R′ is hydrogen, C 1-6 alkyl, heteroalkyl, formyl or C 1-6 alkylcarbonyl, wherein both R 1 and R 1′ exist or alternatively R 1 exists but R 1′ does not exist; R 2 , R 2′ and R 2″ are independently selected from the group consisting of hydrogen, halogen, cyano, nitro, amino, mono-C 1-6 alkyl substituted amino, di-C 1-6 alkyl substituted amino, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, heteroalkyl, hydroxy, and C 1-6 alkoxy; X is phenylene substituted by one, two or three substituents independently selected from the group consisting of halo C 1-6 alkyl, halo C 1-6 alkoxy, C 1-6 alkylsulfonyl, C 1-6 alkylsulfinyl, C 1-6 alkylthio, C 1-6 alkylsulfonyl-C 1-6 alkyl, C 1-6 alkylsulfinyl-C 1-6 alkyl, C 1-6 alkylthio-C 1-6 alkyl, acyl; and Y is at the para position of X with respect to the —NH—SO 2 — group and is selected from the group consisting of: pyridyl, pyrimidinyl and piperidyl, optionally substituted by one or two substituents independently selected from the group consisting of halogen, C1-6 alkoxy and C1-6 alkoxycarbonyl.