Patent ID: 8293858

Claim:
An intraocular lens comprising a polymeric device material, wherein the polymeric device material has an equilibrium water content of: 0.5 to 3 weight percent and is formed by polymerizing a composition comprising a) 75 to 97% (w/w) of a monofunctional monomer of formula [1]: wherein B═O(CH 2 ) n , NH(CH 2 ) n , or NCH 3 (CH 2 ) n ; R 1 ═H, CH 3 , CH 2 CH 3 , or CH 2 OH; n=0-12; A=C 6 H 5 or O(CH 2 ) m C 6 H 5 , where the C 6 H 5 group is optionally substituted with —(CH 2 ) n H, —O(CH 2 ) n H, —CH(CH 3 ) 2 , —C 6 H 5 , —OC 6 H 5 , —CH 2 C 6 H 5 , F, Cl, Br, or I; and m=0-22; b) a difunctional cross-linking monomer of formula [2]: wherein R 2 , R 3 independently═H, CH 3 , CH 2 CH 3 , or CH 2 OH; W, W′ independently═O(CH 2 ) d , NH(CH 2 ) d , NCH 3 (CH 2 ) d , O(CH 2 ) d C 6 H 4 , O(CH 2 CH 2 O) d CH 2 , O(CH 2 CH 2 CH 2 O) d CH 2 , O(CH 2 CH 2 CH 2 CH 2 O) d CH 2 , or nothing; J=(CH 2 ) a , O(CH 2 CH 2 O) b , O, or nothing, provided that if W and W′=nothing, then J≠nothing; d=0-12; a=1-12; and b=1-24; and c) 1 to 8% (w/w) of a macromer of formula [3]: wherein: D=OCH 2 CH 2 S, SCH 2 C═O, CH 3 CH(O)CH 2 S, SCH 2 CH(OH)CH 2 O, S(CH 2 ) 11 O, S(CH 2 ) 10 C═O, S(CH 2 ) 14 C═O, S(CH 2 ) 15 C═O, SC 6 H 4 CH 2 O, CH 3 CH(S)C═O, S(CH 2 CH 2 CH 2 )O, CH 3 CH(S)CH(O)CH 3 , OCH 2 CH 2 C(CH 3 ) 2 S, SCH 2 CH 2 C═O, S(CH 2 ) 4 O, SC 6 H 4 CH 2 C═O, SC 6 H 4 C═O, S(CH 2 ) 11 C═O, CH 3 CH(O)CH(S)CH 3 , SC 6 H 4 C═O, S(CH 2 ) 6 OC 6 H 4 CH 2 O, S(CH 2 ) 6 O, S(CH 2 ) 5 C═O, S(CH 2 ) 7 C═O, or S(CH 2 ) 9 O; E=nothing, O(CH 2 ) n NH, O(CH 2 ) n NHC═O, or HN(CH 2 ) n NH; n=2-12; R 1 ═H, CH 3 , CH 2 CH 3 , or CH 2 OH; and p=10-100.