Patent ID: 7230029

Claim:
A method of treating a proliferative skin disorder comprising the administration of a pharmaceutical composition containing a fatty acid analogue having the following formula R 1 -[x i -CH 2 ] n —COOR 2 wherein R 1 is; a C 2 –C 24 alkene with one or more double bonds and/or with one or more triple bonds, with the proviso that when n is 1 and X i is S, SO or SO 2 then R 1 cannot contain the C≡C—CH 2 moiety attaching to said X i atom, and/or a C 2 –C 24 alkyne, and/or a C 1 –C 24 alkyl, or a C 1 –C 24 alkyl substituted in one or several positions with one or more moieties selected from the group comprising fluoride, chloride, hydroxy, C 1 –C 4 alkoxy, C 1 –C 4 alkylthio, C 2 –C 5 acyloxy or C 1 –C 4 alkyl, and wherein R2 represents hydrogen or C 1 –C 4 alkyl, and wherein n is an integer from 1 to 12, and wherein i is an odd number and indicates the position relative to COOR 2 , and wherein X i independent of each other are selected from the group comprising O, S, SO, SO 2 , Se and CH 2 , and with the proviso that at least one of the X i is not CH 2 , and with the proviso that if R1 is an alkyne or alkene, then the carbon-carbon triple bond or double bond is positioned between the (ω-1) carbon and the (ω-2) carbon, or between the (ω-2) carbon and the (ω-3) carbon, or between the (ω-3) carbon and the (ω-4) carbon, or a salt, prodrug or complex thereof, in an amount and for a period of time sufficient to treat said skin disorder.