Patent ID: 6949536

Claim:
A compound of the formula: or its pharmaceutically acceptable salt thereof, wherein A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated five membered carbocyclic, wherein the 4-(sulfonyl)phenyl and the 4-substituted phenyl in the formula (I) are attached to ring atoms of Ring A adjacent to each other; R 1 is aryl or heteroaryl, and the aryl or heteroaryl being optionally substituted by one to four substituents selected from halo, C 1-4 alkyl, halo-substituted C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkyl carbonyl, hydroxy, nitro, cyano and amino, with the proviso that when A is pyrazole, R 1 is heteroaryl; R 2 is C 1-4 alkyl, halo-substituted C 1-4 alkyl, C 1-4 alkylamino, C 1-4 dialkylamino or amino; R 3 , R 4 and R 5 are independently hydrogen, halo, C 1-4 alkyl, halo-substituted C 1-4 alkyl, C 2-5 alkenyl, C 2-5 alkynyl, C 1-4 alkoxy, hydroxy-C 1-4 alkyl, C 1-4 alkoxy C 1-4 alkyl, C 1-4 alkanoyl, cyano, nitro, cyano C 1-4 alkyl, carboxy, C 1-4 alkoxycarbonyl, aminocarbonyl, N—C 1-4 alkylaminocarbonyl, N,N-di-C 1-4 alkylaminocarbonyl, N-arylaminocarbonyl, N,N-diarylaminocarbonyl, N—C 1-4 alkyl-N-arylamiocarbonyl, aryl, aryloxy, aryloxy-C 1-4 alkyl, heteroaryl, heteroaryloxy, heteroaryloxy-C 1-4 alkyl, morpholino-carbonyl, C 1-4 alkoxyaminocarbonyl or C 1-4 alkyl-carbonylamino; or two of R 3 , R 4 and R 5 are taken together with atoms to which they are attached and form a 4-7 membered ring; R 6 and R 7 are independently hydrogen, halo, C 1-4 alkyl, halo-substituted C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkylthio, C 1-4 alkylamino, N,N-di C 1-4 alkylamino, hydroxyl-C 1-4 alkyl, C 1-4 alkoxy-C 1-4 alkyl, C 1-4 alkyl-C 1-4 alkoxy, C 1-4 alkylamino-C 1-4 alkyl, hydroxy, amino-C 1-4 alkyl and N,N-di C 1-4 alkylamino-C 1-4 alkyl; and m and n are independently 1, 2, 3 or 4. with the proviso that when A contains an oxygen or sulfur heteroatom, one of R 3 , R 4 or R 5 is absent.