Patent ID: 8092472

Claim:
A method of creating and fixating a fold in a wall of a hollow organ, the method comprising: selecting a first tube having a lumen, a proximal end, and a distal end, and placing the distal end of the first tube within the inside of the organ; selecting an elongated second tube having a lumen, a proximal end, and an articulating section terminating in a distal end having a location indicator, and placing the elongated tube through the lumen of the first tube into the interior of the tissue, the elongated tube being rotatable relative to the first tube; passing a piercing element through the lumen of the elongated tube to pierce the wall of the hollow organ at a first location from the inside of the organ to the outside of the organ to create a first hole in the wall of the organ; advancing the elongated tube through the first hole in the wall of the organ; positioning the distal end of the elongated tube near the outer wall of the organ at a desired second location, spaced from the first location, by articulating the articulating section of the elongated tube and rotating the elongated tube as desired; optically detecting from within the organ the position of the distal end of the elongated tube; after the distal end of the elongated tube is optically detected to be at the desired second location, piercing the wall of the organ at the second location from the outside of the organ to the inside of the organ to create a second hole in the wall of the organ; delivering a first tissue anchor and a suture through the first and second holes in the wall of the organ, the suture being attached to the first tissue anchor; delivering a second tissue anchor over the suture and advancing the second tissue anchor over the suture, thereby moving the first and second holes in the wall of the organ towards one another and bringing multiple regions of the outer surface of the organ into apposition; and locking the second tissue anchor onto the suture.