Patent ID: 7955835

Claim:
A process for producing a compound of formula I and a compound of formula VII: wherein R 1 is C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, C 6-12 aryl, C 3-10 heterocycle, C 6-12 aralkyl or C 3-10 heteroaralkyl, and R 2 is CO—C 1-6 alkyl, CO—C 6-12 aryl, CO—C 1-6 alkoxy, CO—C 6-12 aryloxy, or CO—C 6-12 arylalkyl; said process comprising: a) subjecting a compound of formula II: to an enzymatic diastereomeric resolution in the presence of a suitable amount of Pig Liver Esterase enzyme or Porcine Pancreatic Lipase enzyme, wherein said resolution is conducted in the presence of a solvent selected from water, C 1-12 alkanol, toluene, acetonitrile, tetrahydrofuran, dimethylformamide, dimethylsulfonamide, N-methylpyrrolidone, isooctane, t-butylmethyl ether, and mixtures thereof; and b) recovering compounds of formula I and formula VII.