Patent ID: 8597208

Claim:
A device for measuring a concentration of one or more than one compound in a sample derived from a body part of a subject, wherein the sample is measured on the surface of the body part without handling of the sample, comprising: a source of electromagnetic radiation (EMR) that emits one or more than one wavelength of EMR, the source of EMR being operatively coupled to a power source; a probe comprising one or more than one input radiation guiding element in operable association with the source of EMR, one or more than one output radiation guiding element in operable association with a detector, the one or more than one input radiation guiding element and the one or more than one output radiation guiding element optically aligned with one or more than one port located within the probe to define-an EMR path through the probe; a detachable receptor received within the probe and sized to receive the body part, the receptor comprising one or more than one port in optical alignment with the one or more than one port located within the probe to further define the EMR path through the probe and within the receptor; a lancing device and a guide for targeting the lancing device, the lancing device and guide positioned within the receptor to produce a sample from the body part that is disposed on the surface of the body part and directly within the EMR path; and a detector for measuring transmitted or reflected EMR received directly from the sample on the surface of the body part without handling of the sample; and a processing system operatively coupled to the detector, comprising one, or more than one calibration algorithm for determining a concentration for the one or more than one compound; wherein the probe and the receptor received within the probe are removable from the source of EMR, the detector, or both the source of EMR and detector, and are optically associated with the source of EMR and the detector.