Patent ID: 8383113

Claim:
An isolated antibody, or an antigen binding fragment of the antibody, that binds amyloid β-derived diffusible ligands comprising: (a) a light chain variable region comprising, (i) a CDR1 of SEQ ID NO:52 or SEQ ID NO:53; (ii) a CDR2 of SEQ ID NO:57 or SEQ ID NO:58; and (iii) a CDR3 of SEQ ID NO:65 or SEQ ID NO:66; and (b) a heavy chain variable region comprising, (i) a CDR1 of SEQ ID NO: 27 or SEQ ID NO:28, (ii) a CDR2 of SEQ ID NO:32 or SEQ ID NO:37, and (iii) a CDR3 of SEQ ID NO:42, SEQ ID NO:44, SEQ ID NO:45, SEQ ID NO:46, or SEQ ID NO:47.