Patent ID: 7193041

Claim:
A method for synthesizing carboxymethylated aspartate agarose chelating resin, said method comprising: (a) forming oxirane-agarose; (b) conjugating aspartic acid to said oxirane-agarose to produce aspartate agarose, wherein said conjugating aspartic acid to said oxirane-agarose comprises reacting said oxirane-agarose and said aspartic acid at about 80° C. for 4 hours; (c) carboxymethylating said aspartate agarose to produce carboxymethylated aspartate agarose; and (d) complexing said carboxymethylated aspartate agarose with a metal ion other than Ca 2+ to produce a complex that offers two available valencies, wherein said metal ion is a transition metal ion.