Patent ID: 7160867

Claim:
A rapamycin carbohydrate derivative having the structure of formula (I): wherein R 1 and R 2 are independently hydrogen or X—Z, wherein n=0 or 1; and wherein each X is a linker, and each Z is a carbohydrate moiety independently selected from the group consisting of a monosaccharide, oligosaccharide and pseudosugar, wherein Z is attached to X through a hydroxyl oxygen atom of Z with the proviso that R 1 and R 2 are not both hydrogen and wherein X is selected from the group consisting of: (i) —R 3 C(O)—; (ii) —C(O)R 3 —; (iii) —R 3 S(O) 2 —; (iv) —S(O) 2 R 3 —; wherein R 3 is selected from the group consisting of: (a) —(CH 2 ) p — where p is an interger from 1 to 18; (b) —(CH 2 ) n —O—(CH 2 ) m — where n and m are independently an inter from 2 to 6; and (c) a bond.