Patent ID: 7064207

Claim:
A compound of the formula: in which: a. M is NZ or O; b. Z is represented by H or C 1 –C 4 alkyl; c. R 1 is represented by hydrogen, (C 1 –C 2 )alkyl, optionally substituted with one or more halogens, or (C 1 –C 2 )alkoxy, optionally substituted with 1 or more halogens; d. R 2 is absent, or may represent up to 2 substituents selected from the group consisting of halogen, nitrile, hydroxy, (C 1 –C 4 )alkyl, (C 2 –C 4 )alkenyl, (C 2 –C 4 )alkynyl, (C 1 –C 4 )alkoxy, (C 1 –C 2 )alkyl substituted with 1 or more halogens, (C 1 –C 2 )alkoxy substituted with one or more halogens, SR 4 , and NR 4 R 5 ; e. A is represented by —S(O 2 ); f. B completes a heterocyclic ring; g. R 3 may be absent, or may represent up to 2 substituents selected from the group consisting halogen, hydroxy, nirrile, (C 1 –C 4 )alkoxy, (C 1 –C 4 )alkyl, optionally substituted heterocyclic, optionally substituted heteroaryl, optionally substituted phenyl, —[CH 2 ] m C(O)OR 4 , —[CH 2 ] m C(O)R 4 , —[CH 2 ] m C(O)NR 4 R 5 , (C 1 –C 4 )alkylR 6 , —[CH 2 ] n —Y[—CH 2 ] m —X—[CH 3 ]q, (C 3 –C 8 )cycloalkyl, and —SR 4 ; h. R 4 is represented by hydrogen, (C 1 –C 4 )alkyl, optionally substituted benzyl, optionally substituted phenyl, optionally substituted heteroaryl, or optionally substituted heterocyclic or R 4 and R 5 together with the adjacent nitrogen atom can combine to form a heterocyclic or heteroaryl ring; i. R 5 is represented by hydrogen, optionally substituted phenyl, (C 1 –C 4 )alkyl, or optionally substituted benzyl; j. R 6 is represented by optionally substituted phenyl, optionally substituted heteroaryl, or optionally substituted heterocyclic; k. n is an integer selected from 1, 2, 3, or 4; l. Y is absent, or is represented by O, C(O), OH, SH, or S; m. m is represented by an integer selected from 0, 1, 2, 3, or 4; n. X is absent, or is represented by O, C(O), OH, SH or S; and o. q is represented by the integer 0 or 1; or a pharmaceutically acceptable salt, or solvate, thereof: with the previsio that: 1) if both X and Y are present, then m is not zero, and 2) if M is represented by oxygen, then R 1 must be trifluoromethyl.