Patent ID: 8524694

Claim:
A sterol-based compound, corresponding to formula (I) wherein: T 1 and T 2 represent, independently, H or CH 3 with CH 3 in the α and/or β position; T 4 represents H, CH 3 or C 2 H 5 ; T 3 represents H or a β CH 3 ; the bond between carbons 5 and 6 is a single bond and the bond between carbons 7 and 8 is a single or a double bond; Z is in position 5 and represents OH; and R is in position 6 or 7, on a carbon not bearing a double bond, and represents a substituent of formula -Q 0 -Q 1 wherein: -Q 0 - represents the radical of formula (II): —X—(CH 2 ) no [Y 1 —(CH 2 ) n1 ] p1 [Y 2 —(CH 2 ) n2 ] p2 [Y 3 —(CH 2 ) n3 ] p3 [Y 4 —(CH 2 ) n4 ] p4 [Y 5 —(CH 2 ) n5 ] p5 — (II) in which formula (II): p1, p2, p3, p4 and p5 are integers independently equal to 0 or 1, n0, n1, n2, n3, n4 and n5 are independent integers such that: 1 ≦n 0≦4 0 ≦n 1 ,n 2 ,n 3 ,n 4 ,n 5≦4 —X— represents —S—, —O—, —CH 2 —, —NR 3 —, in which R 3 is H or a C 1 -C 4 alkyl radical, or a heterocycle —Y 1 —, —Y 2 —, —Y 3 —, —Y 4 — and —Y 5 — represent, independently of each other, —S—, —O—, —CH 2 — or —NR 3 —, in which R 3 has the meaning given above; -Q 1 represents an indole nucleus, a morpholine or thiomorpholine nucleus attached via its nitrogen atom, a heterocycle in which R 1 represents H, COCH 3 , or a C 1 -C 4 alkyl radical, or Q 1 represents in which R 1 has the meanings given above and R 2 represents H or a C 1 -C 4 alkyl radical, or R 1 and R 2 together constitute a piperidine, pyridine or piperazine ring optionally substituted with a C 2 -C 4 alkyl radical, or constitute a pyrrole or pyrrolidine heterocycle comprising a nitrogen atom and 4 carbon atoms, with the proviso that: if —X-=—NH— and at least one of the numbers p1, p2, p3, p4 and p5 is other than 0; and if —X—=—CH 2 —, n0=1 and all the numbers p1, p2, p3, p4 and p5 are zero, Q 2 is other than —NH 2 .