Patent ID: 8367663

Claim:
A compound represented by formula (I); or a geometric isomer, enantiomer, diastereomer, racemate, pharmaceutically acceptable salt, or prodrug thereof, wherein represents a single or double bond; q, r and s are independently 0 or 1, wherein at least one of q, r and s is 1; t is 0 or 1; n is 0, 1, 2, 3 or 4; p is 0, 1 or 2; X is CR 1 , N(R 8 ), S or O; Y is CR 1 , S or O; provided that X and Y are not both CR 1 ; G 1 is CR 1 , S, O, NR 10 or NS(O) 2 R 10 ; G 2 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or, substituted or unsubstituted heterocyclic; G 3 is substituted or unsubstituted C 1 -C 8 alkyl, substituted or unsubstituted C 2 -C 8 alkenyl, or, substituted or unsubstituted C 2 -C 8 alkynyl; each R 8 is independently hydrogen, acyl, aliphatic or substituted aliphatic; each R 1 and R 2 is independently selected from absent, hydrogen, hydroxy, amino, halogen, alkoxy, alkylamino, dialkylamino, CF 3 , CN, NO 2 , sulfonyl, acyl, aliphatic, substituted aliphatic, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; R a is optionally substituted alkyl, optionally substituted aryl or optionally substituted heteroaryl; R b is hydrogen, optionally substituted alkyl, optionally substituted aryl or optionally substituted heteroaryl; or R a and R b , together with the nitrogen atom to which they are attached, form an optionally substituted heterocyclic group; R 10 is selected from hydrogen, hydroxy, amino, alkoxy, alkylamino, dialkylamino, sulfonyl, acyl, aliphatic, substituted aliphatic, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; B is a linker; and C is where W is O or S; J is O, NH or NCH 3 ; and R 31 is hydrogen or lower alkyl.