Patent ID: 6916906

Claim:
A composition comprising: (a) an isolated protein having the amino acid sequence of SEQ ID NO:2 or a fragment of SEQ ID NO:2, wherein said protein or fragment when combined with (b) and (c) confers resistance to glycopeptides in Gram-positive bacteria; (b) an isolated protein having the amino acid sequence of SEQ ID NO:6 or a fragment of SEQ ID NO:6, wherein said protein or fragment when combined with (a) and (c) confers resistance to glycopeptides in Gram-positive bacteria; and (c) an isolated protein or protein fragment selected from the group consisting of a protein having the amino acid sequence of SEQ ID NO:4, a fragment of SEQ ID NO:4, a protein having the amino acid sequence of SEQ ID NO:25, and a fragment of SEQ ID NO:25, wherein said protein or protein fragment when combined with (a) and (b) confers resistance to glycopeptides in Gram-positive bacteria; wherein the composition confers resistance to glycopeptides in Gram-positive bacteria.