Patent ID: 7241890

Claim:
A compound of formula: wherein, X is S; A is NH 2 or CH 3 ; Z is selected from the group of F, Cl, Br and CF 3 ; Y is selected from the group of optionally substituted C 2 -C 8 alkyl, optionally substituted C 3 -C 8 alkenyl, optionally substituted C 3 -C 8 alkynyl, optionally substituted C 6 -C 10 aryl, and optionally substituted C 3 -C 10 alicyclic; Q is a member selected from the group of: L is O, S or NR 1 ; R 1 is independently selected from the group of H, optionally substituted C 1 -C 6 alkyl, optionally substituted C 3 -C 10 cycloalkyl, optionally substituted aryl, optionally substituted heterocyclic, C(O)R 2 , C(O)OR 2 , C(O)NR 4 2 , C(S)OR 2 , C(S)NR 4 2 , and S(O) 2 R 2 ; R 2 is independently selected from the group of C 1 -C 6 alkyl, C 3 -C 10 cycloalkyl, heterocyclic, heteroaryl, and aryl, all optionally substituted; R 3 is independently selected from the group of H, optionally substituted C 1 -C 6 alkyl, optionally substituted C 3 -C 10 cycloalkyl, optionally substituted aryl, optionally substituted heterocyclic and C(O)NR 4 2 ; R 4 is independently selected from the group of H, optionally substituted C 1 -C 6 alkyl, optionally substituted C 3 -C 10 cycloalkyl, optionally substituted aryl, and optionally substituted heterocyclic; and each R 6 is independently selected from the group of H, optionally substituted C 1 -C 6 alkyl, lower cycloalkyl, OR 3 , SR 3 , NHR 3 , C(O)N(R 4 ) 2 , NO 2 , CN, halogen, and S(O) 2 R 2 ; or a tautomer or a pharmaceutically acceptable salt or prodrug thereof.