Patent ID: 8092834

Claim:
A method of improving the condition of rough skin, which condition accompanies an activity change for a plasminogen activator, comprising applying to rough skin an external composition including a complex powder, the complex powder comprising: an adsorption site comprising a material selected from the group consisting of silica, talc, mica, polymethyl methacrylate, silicone resin and combinations thereof and an operation site, including zinc oxide, wherein said adsorption site attracts or adsorbs a plasminogen activator, wherein said operation site inhibits said plasminogen activator, and wherein said adsorption site and said operation site are present on the surface of the complex powder, wherein the operation site takes the form of stripes or spots on the surface of the adsorption site, and wherein 2 to 70% of the surface area of the adsorption site is covered by the operation site.