Patent ID: 8530459

Claim:
A chlorin of Formula Va or bacteriochlorin of Formula Vb: wherein: M is a metal or is absent; X 1 , X 2 , X 3 and X 4 are each independently selected from the group consisting of Se, NH, CH 2 , O and S; at least one pair of R 11 and R 12 , R 13 and R 14 , R 21 and R 22 , and R 23 and R 24 are both independently selected Alk′R′, wherein Alk′ is a C 1-C50 alkylidene chain, and R′ is an ionic group, polar group, bioconjugatable group, or targeting group; R 11 , R 12 , R 15 , R 16 , R 17 , R 18 , R 21 , R 22 , R 23 , R 24 , R 25 , R 26 , R 27 , and R 28 are each independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, cycloalkylalkenyl, cycloalkylalkynyl, heterocyclo, heterocycloalkyl, heterocycloalkenyl, heterocycloalkynyl, aryl, aryloxy, arylalkyl, arylalkenyl, arylalkynyl, heteroaryl, heteroarylalkyl, heteroarylalkenyl, heteroarylalkynyl, alkoxy, halo, mercapto, azido, cyano, acyl, formyl, carboxylic acid, acylamino, ester, amide, hydroxyl, nitro, alkylthio, amino, alkylamino, arylalkylamino, disubstituted amino, acyloxy, sulfoxyl, sulfonyl, sulfonate, sulfonic acid, sulfonamide, urea, alkoxylacylamino, aminoacyloxy, linking groups, surface attachment groups, and groups of Formula II: wherein R 4 and R 5 are each independently an ionic group or polar group, and Alk 3 and Alk 4 are each independently a C1-C50 alkylidene chain; wherein each of R 11 and R 12 , R 13 and R 14 , R 21 and R 22 , or R 23 and R 24 can together form═O; and wherein each of R 11 and R 12 , R 13 and R 14 , R 21 and R 22 , or R 23 and R 24 , can together form spiroalkyl; or R 23 is Alk 41 R 41 wherein Alk 41 is a C1-C50 alkylidene chain, and R 41 is an ionic group, polar group, bioconjugatable group, or targeting group; or R 24 is Alk 42 R 42 wherein Alk 42 is a C1-C50 alkylidene chain, and R 42 is an ionic group, polar group, bioconjugatable group or targeting group; or a salt thereof.