Patent ID: 7452996

Claim:
A compound of formula I: wherein: m is an integer from 0 to 3; R 1 is selected from the group consisting of acylamino, carboxyl ester, and C 1 to C 5 alkyl optionally substituted with hydroxy, or halo; R 2 is hydrogen or C 1 to C 5 alkyl; R 3 is —C(═X)-A, wherein A is selected from the group consisting of aryl, heteroaryl, heterocyclic, and cycloalkyl, all of which may be optionally substituted with 1 to 4 substituents selected from the group consisting of C 1 to C 4 alkyl, C 1 to C 4 alkoxy, halo, hydroxy, and nitro and X is oxygen or sulfur; R 4 is -alkylene-heterocyclic or -alkylene-NR 7 R 8 wherein alkylene is a C 1 to C 4 straight chained alkylene; R 7 and R 8 are independently selected from the group consisting of hydrogen, C 1 to C 4 alkyl, arylalkyl, heteroarylalkyl, cycloalkyl and cycloalkylalkyl; R 5 is selected from the group consisting of L-A 1 , wherein A 1 is selected from the group consisting of aryl, heteroaryl, heterocyclic, and cycloalkyl, all of which may be optionally substituted with 1 to 4 substituents selected from the group consisting of C 1 to C 4 alkyl, C 1 to C 4 alkoxy, halo, hydroxy, and nitro and wherein L is selected from the group consisting of oxygen, —NR 9 where R 9 is hydrogen or alkyl, —S(O) q — where q is zero, one or two, and C 1 to C 5 alkylene, optionally substituted with hydroxy, halo, or acylamino; and R 6 is selected from the group consisting of C 1 to C 5 alkyl, C 2 to C 5 alkenyl, C 2 to C 5 alkynyl, —CF 3 , C 1 to C 5 alkoxy, halo, and hydroxy; or a pharmaceutically acceptable salt thereof.