Patent ID: 8043629

Claim:
A bioabsorbable synthetic non-woven fabric holding a hemostatic-effective amount of thrombin, said non-woven fabric being made of a material comprising polyglycolic acid, said non-woven fabric having sufficient elasticity and flexibility for sealing tissues of various shapes, formed by contacting a bioabsorbable synthetic non-woven fabric with a saline solution comprising thrombin optionally containing a pharmaceutically acceptable additive selected from the group consisting of albumin, polyethylene glycol, arginine, hyaluronic acid, glycerol, mannitol and calcium chloride, and lyophilizing the non-woven fabric holding the thrombin, said bioabsorbable synthetic non-woven fabric being formed by said contacting of the bioabsorbable synthetic nonwoven fabric with the saline solution, wherein said saline solution consists of said thrombin alone or said thrombin containing said pharmaceutically acceptable additive.