Patent ID: 6995283

Claim:
A compound of formula (IA) wherein: R 1 is one or more substituents independently selected from the group consisting of halogen, —CF 3 , C 1-8 alkyl, aminoC 1-8 alkyl, alkoxy, —CN, —NO 2 , —NH 2 , —SR 8 , —S(O)R 8 , —S(O) 2 R 8 , —C(O)R 8 ; C 2-6 alkenyl which may be optionally substituted with a substituent selected from the group consisting of hydroxy, halogen, C 3-6 cycloalkyl, C 6-14 aryl and heterocycle; C 2-6 alkynyl which may be optionally substituted with a substituent selected from the group consisting of hydroxy, halogen, C 6-14 aryl, C 3-6 cycloalkyl, and heterocycle; and heterocycle, optionally substituted with one or more substituents selected from the group consisting of halogen, C 1-8 alkyl, —CN, C 1-8 alkylC 6-14 aryl and heterocycle; R 2 is selected from the group consisting of hydrogen, halogen, C 1-8 alkyl, —NO 2 , —NH 2 , C 1-8 alkylamino, —CF 3 and alkoxy; R 3 is selected from the group consisting of hydroxy, halogen, —CF 3 , —NO 2 and C 1-8 alkyl; R 4 is selected from the group consisting of —S(O) 2 NR 5 R 6 , —S(O) 2 N═C(OR 7 ) 2 and —S(O) 2 N═CR 7 (OR 7 ); R 5 is selected from the group consisting of hydrogen, C 6-14 aryl, C 1-8 alkyl, C 3-6 cycloalkylC 1-8 alkyl and C 3-6 cycloalkyl; R 6 is selected from the group consisting of —C(O)R 7 , —C(O)OR 7 , —C(O)C(O)OR 7 , —C(O)CH(NR 12 R 13 )R 11 , alkoxyC 1-8 alkyl and —CH 2 O—(CH 2 CH 2 O) n —CH 2 CH 2 OCH 3 , wherein n is 0-4; R 7 is selected from the group consisting of C 3-6 cycloalkylC 1-8 alkyl, hydroxyC 1-8 alkyl, C 6-14 aryl, heterocycle optionally substituted with C 1-8 alkyl, C 6-14 arylC 1-8 alkyl, —(CH 2 CH 2 —O) n —CH 3 , where n=1-4, alkoxyC 1-8 alkyl and C 1-8 alkyl optionally substituted with —O—C(O)R 12 ; R 8 is selected from the group consisting of C 1-8 alkyl, C 3-6 cycloalkylC 1-8 alkyl, C 3-6 cycloalkyl, C 6-14 aryl and heterocycle; R 11 is selected from the group consisting of hydrogen, R 12 and R 13 are independently selected from the group consisting of hydrogen, C 1-8 alkyl, C 3-6 cycloalkyl and C 6-14 aryl; or a pharmaceutically acceptable derivative thereof.