Patent ID: 8518676

Claim:
A host cell comprising a heterologous polynucleotide that encodes a C4-dicarboxylic acid transporter, wherein the heterologous polynucleotide: (a) encodes a C4-dicarboxylic acid transporter having at least 95% sequence identity to SEQ ID NO: 4, or the mature polypeptide sequence thereof; (b) hybridizes under high stringency conditions with the full-length complementary strand of SEQ ID NO: 3; or (c) has at least 95% sequence identity to SEQ ID NO: 3, or the mature polypeptide coding sequence thereof; wherein the host cell is capable of producing a greater amount of C4 dicarboxylic acid compared to the host cell without the heterologous polynucleotide when cultivated under the same conditions.