Patent ID: 8879867

Claim:
A method for real-time enhancement of a signal of interest in a video, the method comprising: receiving a source video acquired using a multi-channel video acquisition system with C channels where channel k=1 . . . C, said source video comprising a plurality of image frames, each frame comprising an array of pixels, each pixel having an intensity value corresponding to detected reflected energy projected by an illumination source over a wavelength range of interest; for each pixel location (i, j) of each image frame of each channel k of said source video: determining a measure of closeness with respect to a reference signal R(t) in both a spatial and time direction; identifying, using said measure of closeness, a time-series signal I(t) of interest in said source video, where signal I ijk (t) appears at pixel location (i, j, k); in response to having identified said time-series signal of interest at pixel location (i, j, k): modifying an intensity of said pixel at said location to generate modified video data J ijk (t); and retrofitting said modified video data into said source video to generate a reconstructed source video; and communicating said reconstructed source video to a display device.