Patent ID: 7132408

Claim:
A compound of Formula Ib′ or salts thereof: wherein: V═O; A═M; M═H or a pharmaceutically-acceptable inorganic or organic counterion; D 1 ═O; Y′═OR 1 ; Z′═OR 2 ; R 1 and R 2 are residues which are linked directly to two of the 2′ and 3′ hydroxyls of the furanose via a common carbon atom according to Formula III, wherein: O is the 2′ and 3′ oxygens of the furanose; and the 2′ and 3′ oxygens of the furanose are linked by a common carbon atom to form a cyclical acetal; and R 8 is hydrogen; and R 9 is selected from the group consisting of aralkyl, aryl, substituted aralkyl, and substituted aryl; in which the aralkyl groups are straight chained from 1 to 5 carbons, with or without unsaturation and without heteroatoms in the alkyl portion, and are monocyclic moieties from 5 to 6 carbons in the aryl portion; and in which the aryl groups are monocyclic moieties from 4 to 6 carbons, with or without heteroatoms; B′ is a purine residue according to general Formula IV: wherein J=carbon; R 11 is absent; R 12 is hydrogen; R 13 is hydrogen; R 10 is acylamino, according to Formula VI; wherein: NH is the amino residue at the C-6 position in a purine; C is a carbon atom; W 1 is oxygen; and R 17 is amino or mono- or disubstituted amino such that the moiety according to Formula VI is a urea.