Patent ID: 8575143

Claim:
A compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein R a is a halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl-O—, substituted or unsubstituted alkyl-O—, substituted or unsubstituted alkenyl-O— or substituted or unsubstituted alkynyl-O—, wherein alkyl, alkenyl and alkynyl are optionally interrupted by NR, O or S(O) n ; each R 2 is independently selected from the group consisting of substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted non-aromatic heterocyclic, —CN, —COOR′, —CON(R) 2 , —NRC(O)R, —SO 2 N(R) 2 , —N(R) 2 , —OH and —OR′; each R 3 is independently selected from the group consisting of halogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted non-aromatic heterocyclic, —CN, —COOR′, —CON(R) 2 , —NRC(O)R, − SO 2 N(R) 2 , —N(R) 2 , —NO 2 , —OH and —OR′; R 4 and R 5 are independently selected from the group consisting of —H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted non-aromatic heterocyclic and substituted or unsubstituted aryl, wherein alkyl, alkenyl and alkynyl are optionally interrupted by NR, O or S(O) n ; or R 4 and R 5 taken together form a carbocyclic or heterocyclic group; V is —NH-L-A-Q or Ring C is a substituted or unsubstituted heterocyclic aromatic or non-aromatic ring; A is NR or O; or A is a covalent bond; L is a substituted or unsubstituted hydrocarbyl group optionally interrupted by one or more heteroatoms selected from N, O and S; Q is selected from the group consisting of —R, —C(O)R′, —C(O)N(R) 2 , —C(O)OR′ and —S(O) 2 R′; each R is independently —H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl or substituted or unsubstituted non-aromatic heterocyclic; each R′ is independently a substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl group, substituted or unsubstituted non-aromatic heterocyclic or substituted or unsubstituted aryl group; j is an integer from 1 to 4; k is an integer from 0 to 4; and each n is independently 0, 1 or 2.