Patent ID: 8483825

Claim:
A system comprising: an implantable medical device configured to receive intrinsic cardiac information from a subject, the implantable medical device including: an atrial sensing channel configured to receive an intrinsic atrial activation; a left ventricular sensing channel configured to receive an intrinsic left ventricular activation; and a right ventricular sensing channel configured to receive an intrinsic right ventricular activation; and a processor configured to: detect any one of: (1) a left intraventricular conduction defect and no right intraventricular conduction defect; (2) no left intraventricular conduction defect and a right intraventricular conduction defect; (3) no left intraventricular conduction defect and no right intraventricular conduction defect; and (4) a left intraventricular conduction defect and a right intraventricular conduction defect, using the intrinsic cardiac information; determine a right intrinsic atrioventricular interval, a ventricular depolarization duration, a left intrinsic atrioventricular interval, an interval between an atrial pace and a first ventricular activation, and a detected intrinsic AV interval (AVI); calculate a first atrioventricular (AV) delay using at least one of: (1) a function of a right intrinsic atrioventricular interval (AV R ) and a ventricular depolarization duration, (2) a function of AV R and a left intrinsic atrioventricular interval (AV L ) and (3) a function of an interval between an atrial pace and a first ventricular activation (A p V first ), when detecting the left intraventricular conduction defect or no intraventricular conduction defect; and calculate a second AV delay using a function of a detected intrinsic AVI when detecting right intraventricular conduction defect, wherein the intrinsic AVI is the interval between an atrial event and an RV depolarization, an LV depolarization, or the ventricle having the first intrinsic depolarization following the atrial event.