Patent ID: 7157049

Claim:
An optical bio-disc for conducting a cellular assay, said disc comprising: a rotatable substrate; a cap portion associated with said substrate; and a fluidic circuit formed between said substrate and said cap portion, said fluidic circuit comprising: a mixing chamber, said mixing chamber including an inlet port configured to receive a fluid including RBC's; a RBC capture zone in fluid communication with the mixing chamber so as to receive a fluid therefrom; a plurality of posts with RBC capture agents coated thereon and located within the RBC capture zone, the posts being configured to capture RBC's while allowing passage through said RBC capture zone of non-RBC materials included in the fluid; a purification chamber in fluid communication with said capture zone, the purification chamber configured to receive mixed fluid communicated from the mixing chamber; a filter associated with said purification chamber; an analysis chamber in fluid communication with said purification chamber, said analysis chamber including a capture zone; and a vent port associated with said analysis chamber.