Patent ID: 8071625

Claim:
A compound selected from compounds of Formula I and pharmaceutically acceptable salts thereof, wherein W 1 is selected from CR 11 R 12 , NR 13 , and O; W 2 is NR 13 ; W 3 is CR 1 R 2 ; Z 1 is aryl; Z 2 is aryl; R 8 is selected from hydrogen and optionally substituted alkyl; R 11 and R 12 are independently selected from hydrogen and optionally substituted alkyl; R 1 and R 2 together with the carbon to which they are attached, form a group selected optionally substituted piperidinyl and optionally substituted tetrahydropyranyl; R 13 is selected from hydrogen and optionally substituted alkyl; for each occurrence, R 3 , R 4 , R 5 , and R 6 are independently selected from hydrogen, hydroxyl, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted alkoxy, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted heterocycloalkyloxy, optionally substituted aminocarbonyloxy, optionally substituted acyloxy, optionally substituted alkoxycarbonyloxy, optionally substituted acyl, optionally substituted alkoxycarbonyl, optionally substituted amino, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocycloalkyl, optionally substituted aminocarbonyl, and optionally substituted aminosulfonyl; R 7 and R 10 are independently selected from hydrogen, cyano, halo, hydroxy, carboxy, azido, nitro, sulfonyl, sulfinyl, sulfanyl, optionally substituted alkoxy, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted heterocycloalkyloxy, optionally substituted alkoxycarbonyl, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocycloalkyl, optionally substituted amino, optionally substituted acyl, optionally substituted aminocarbonyl, optionally substituted aminosulfonyl, optionally substituted carbaminodoyl; m is selected from 0, 1, 2 and 3; n is selected from 0, 1, 2, 3, and 4; p is selected from 0, 1, 2, and 3; and q is selected from 0, 1, 2, 3, and 4.