Patent ID: 8722917

Claim:
A compound, or a pharmaceutically acceptable salt thereof, having a structure according to the following formula: in which R 1 and R 2 are members independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; wherein R 1 and R 2 , together with the atoms to which they are attached, can be optionally joined to form a 4- to 7-membered ring; Z1 is a member selected from wherein R 3a and R 4a are members independently selected from H, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; R 5 is a member selected from halogen and OR 8 wherein R 8 is a member selected from substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, unsubstituted aryl, and substituted or unsubstituted heteroaryl R 9a is H, R 11a is H, R 12a is H, and R 10a is halogen.