Patent ID: 8895599

Claim:
A method for activating LPL in a patient in need of LPL activation treatment, comprising administering an effective amount of a benzene compound into the patient, the benzene compound being represented by General Formula (1): wherein R 1 is lower alkoxy; R 2 , R 3 and Z are any one of the groups (1-1) to (1-3): (1-1) R 2 is phenyl, phenyl having one or two halogen atoms as substituents on the benzene ring, phenyl lower alkyl group, phenyl lower alkyl group having on the benzene ring one or two substituents selected from the group consisting of halogen, and cyano, or R 1 and R 2 are jointed to form —CH═C(Ph)- (wherein Ph is phenyl); R 3 is hydrogen or lower alkoxy; and Z is a group represented by the formula below: wherein R 4 is hydrogen, lower alkyl, or halogen; R 5 is hydrogen, lower alkyl, halogen, hydroxy, lower alkoxy, phenyl lower alkoxy; R 6 is hydrogen, lower alkyl, carboxy, or halogenated lower alkyl; R 7 is hydrogen, lower alkyl, halogen, halogenated lower alkyl, lower alkoxycarbonyl, carboxy, cyano, carbamoyl, or phenyl; and R 8 is hydrogen or lower alkyl; (1-2) R 2 is phenyl lower alkyl having one or two halogen atoms as substituents on the benzene ring: R 3 is hydrogen or lower alkoxy; and Z is imidazo[2,1-b]thiazol-6-yl or imidazo[2,1-b]thiazol-6-yl having one lower alkyl substituent; and (1-3) R 2 is phenyl lower alkyl, or phenyl lower alkyl having one or two halogen atoms as substituents on the benzene ring; R 3 is hydrogen or lower alkoxy; and Z is imidazo[1,2-a]pyridin-3-yl.