Patent ID: 7960567

Claim:
A compound having formula II or III: or a pharmaceutically acceptable salt, thereof, wherein B is a fused 5-membered ring consisting of carbon atoms and 1 heteroatom, wherein the heteroatom is nitrogen; optionally, B is substituted with halogen, (C 1 -C 3 )alkyl, halo(C 1 -C 3 )alkyl, cyclo(C 3 -C 5 )alkyl, amino(C 1 -C 3 )alkyl, hydroxy, oxo, —OR′, —CONR′R″, —N(R″)C(O)R′, —CO 2 R′, or —CN; X is —O—; Y is —S(O) k NR 10 ; Z is —CO 2 R 12 ; L is (C 1 -C 6 )alkylene; R 2 is a substituted or unsubstituted aryl, wherein the substituted aryl is substituted with 1 to 5 substituents independently selected from -halogen, —OR′, —OC(O)R′, —NR′R″, —SR′, —R′, —CN, —NO 2 , —CO 2 R′, —CONR′R″, —C(O)R′, —OC(O)NR′R″, —NR″C(O)R′, —NR″C(O) 2 R′, —NR′—C(O)NR″R′″, —NH—C(NH 2 )═NH, —NR′C(NH 2 )═NH, —NH—C(NH 2 )═NR′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —N 3 , —CH(Ph) 2 , perfluoro(C 1 -C 4 )alkoxy, or perfluoro(C 1 -C 4 )alkyl; R 3 , R 5 and R 6 are independently hydrogen, halogen, (C 1 -C 8 )alkyl, fluoro(C 1 -C 4 )alkyl, —NR′R″, —OR′, —NO 2 , —CN, —C(O)R′, —CO 2 R′, —C(O)NR′R″, (C 1 -C 4 )alkylene-C(O)NR′R″, —S(O) m R′, —S(O) k NR′R″, —OC(O)OR′, —OC(O)R′, —OC(O)NR′R″, —N(R′″)C(O)NR′R″, —N(R″)C(O)R′, —N(R″)S(O) k R′ or —N(R″)C(O)OR′; R 10 is selected from hydrogen or (C 1 -C 8 )alkyl; R 12 is selected from hydrogen or (C 1 -C 6 )alkyl; each R 14 is independently halogen, (C 1 -C 8 )alkyl, fluoro(C 1 -C 4 )alkyl, (C 2 -C 5 )alkenyl, —OR′, —NR′R″, —NO 2 , —CN, —C(O)R′ or aryl; each R′, R″ and R′″ is independently hydrogen or (C 1 -C 6 )alkyl; subscript k is 2; subscript m is 0, 1, 2 or 3; and subscript n is 0, 1, 2, 3 or 4.