Patent ID: 7923037

Claim:
A sterile, stable aqueous pharmaceutical composition comprising: a solution of deoxygenated water and sodium sulfide nonahydrate, wherein the sodium sulfide nonahydrate produces Na 2 S, H 2 S and HS − , wherein the concentration of H 2 S is in the range of 1.0 mg/mL to 4.0 mg/mL; wherein the solution is adjusted to a pH in the range of 7.5 to 8.5 by adding HCI to the solution; wherein the solution has an osmolarity in the range of 250-330 mOsmol/L; wherein the solution further comprises sulfide oxidation products selected from the group consisting of polysulfide, sulfite, sulfate and thiosulfate; wherein the oxidation products comprise sulfate in the range of (0%-1.0%), sulfite in the range of (0%-1.0%), polysulfide in the range of (0%-1%) or thiosulfate in the range of (0%-1.0%); wherein the solution is isotonic or near isotonic; and, wherein the solution is stable for at least four months.