Patent ID: 8865736

Claim:
A substituted benzamide compound of formula (I) or a salt, hydrate, or solvate thereof, for use in treating bacterial infection: wherein R represents hydrogen or 1, 2 or 3 optional substituents; W is ═C(R 1 )—; R 1 is hydrogen and R 2 is hydrogen, methyl, or fluorine; R 3 is a radical of formula -(Alk 1 ) m -(Z) p -(Alk 2 ) n -Q wherein m and n are independently 0; p is 1; and the divalent radical Z is selected from the following, optionally substituted, in either orientation: Q is an optionally substituted phenyl, wherein optionally substituted means substituted with up to four substituents independently selected from the group consisting of (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkoxy, hydroxy, hydroxy(C 1 -C 6 )alkyl, mercapto, mercapto(C 1 -C 6 )alkyl, (C 1 -C 6 )alkylthio, halo, fully or partially fluorinated (C 1 -C 3 )alkyl, (C 1 -C 3 )alkoxy or (C 1 -C 3 )alkylthio, nitro, nitrile (—CN), oxo (═O), phenyl, phenoxy, cyclopropel, monocyclic heteroaryl or heteroaryloxy with 5 or 6 ring atoms, —COOR A , —COR A , —OCOR A , —SO 2 R A , —CONR A R B , —SO 2 NR A R B , —NR A R B , OCONR A R B , —NR B COR A , —NR B COOR A , —NR B SO 2 OR A or —NR A CONR A R B wherein R A and R B are independently hydrogen or a (C 1 -C 6 )alkyl group or, in the case where R A and R B are linked to the same N atom, R A and R B taken together with that nitrogen may form a cyclic amino ring, wherein where the substituent is phenyl, phenoxy or monocyclic heteroaryl or heteroaryloxy with 5 or 6 ring atoms, the phenyl or heteroaryl ring thereof may itself be substituted by any of the above substituents except phenyl phenoxy, heteroaryl, or heteroaryloxy.