Patent ID: 7906134

Claim:
A method of preparing a composition, said composition comprising at least one therapeutic compound and a molecule of formula IV: said method comprising reacting a molecule of formula I: in situ with a molecule of formula II: adding the therapeutic compound to reactant (I) or reactant (II) or both prior to the reaction thereof, or adding the therapeutic compound to the reaction mixture of the reactants during the reaction thereof; wherein R 1 comprises a polymer, the polymer containing at least one group selected from the group consisting of an acyloxy, alkenyl, alkoxyl, alkyl, alkylcycloalkenyl, alkylcycloalky, alkenylcycloalkyl, alkynyl, amino, aralkyl, aryl, cycloalkenyl, cycloalkenylalkyl, cycloalkyl, cycloalkylalkyl, cycloalkylcycloalkyl, halogen, heterocycle, heterocyclic, ketone, N-acylamino, N-containing heterocycle; and combinations thereof; and R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are alkyls or silanol-terminated alkyls; and wherein n is an integer, 1≦n≦100; and wherein the reaction is carried out at a temperature compatible with the therapeutic compound.