Patent ID: 7825110

Claim:
A compound having the structure shown in Formula I: or pharmaceutically acceptable salts, racemic mixtures, diastereomers and enantiomers thereof wherein: one of X and Y is CH 2 and the other is NR 1 ; Z is CH or N; V is H, C 1-3 alkyl, C 1-3 alkoxy or halogen; n=1 or 2, W is H, C 1-3 alkoxy; or hydroxyl; R 1 is H, C 1-5 alkyl, arylalkyl, C 3-5 cycloalkyl, —CH 2 —C(O)OR 5 , —C(O)R 4 , —C(O)(CH 2 ) m —N(R 6 )(R 6 ), or —C(O)—CH 2 —C(O)OR 5 , where R 4 is C 1-3 alkyl, R 5 is H or C 1-3 alkyl and m is 1 to 3; R 2 is H, halogen, C 1-5 alkyl, C 1-3 alkoxy or aryl; R 3 is H, halogen, C 1-5 alkyl, C 1-3 alkoxy or aryl; with the proviso that at least one of R 1 , R 2 and R 3 is not H; and the R 6 moieties can be the same or different, each being independently selected from the group consisting of H, C 1-6 alkyl, and C 3-5 cycloalkyl; or alternatively two R 6 moieties can be linked together with the N to which they are attached to form a 5 to 6 membered heterocyclyl.