Patent ID: 8748429

Claim:
A compound of Formula 1 such that ring A is selected from the group consisting of and wherein R 1a is hydrogen, cyano, halo, alkyl, haloalkyl, alkoxy, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, or piperidinyl; R 1b is hydrogen, alkyl, or haloalkyl; R 2 is piperidinyl substituted with 1 substituent selected from the group consisting of or R 2 is R 3 is hydrogen, halo, cyano, alkyl, haloalkyl, alkoxy, or haloalkoxy; R 4 is hydrogen, halo, cyano, alkyl, haloalkyl, alkoxy, or haloalkoxy; R 5 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 6 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 7 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 8 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 9 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 10 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, alkoxycarbonylamino, or benzyloxycarbonylamino; R 11 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, alkoxycarbonylamino, or benzyloxycarbonylamino; or R 10 and R 11 taken together is O or N—OH; provided that at least one of R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , or R 11 is not hydrogen; Ar 1 is phenyl substituted with 0-3 substituents selected from the group consisting of cyano, halo, alkyl, haloalkyl, alkoxy, haloalkoxy, and alkylSO 2 ; X is O, CH 2 , or NH; and Y is a bond, O, CH 2 , or NH; or a pharmaceutically acceptable salt thereof.