Patent ID: 8563000

Claim:
A compound of formula (II) wherein X1 is X2 is A1 is Asp, Cys, D-Cys, Dab, Dap, Glu, Lys, Orn, Pen or D-Pen; A2 is an L- or D-amino acid; A3 is His, 2-Pal, 3-Pal, 4-Pal, Phe, Taz, 2-Thi or 3-Thi; A4 is D-Bal, D-1-Nal, D-2-Nal, D-Phe; A5 is Arg, hArg, Dab, Dap, Lys or Orn; A6 is Bal, 1-Nal, 2-Nal, Phe or Trp; A7 is Asp, Cys, D-Cys, Dab, Dap, Glu, Lys, Orn, Pen or D-Pen; R1 is H, (C1-C10)alkyl or substituted (C1-C10)alkyl; R2 and R3 each is, independently, H, (C1-C10)alkyl, (C1-C10)heteroalkyl, aryl(C1-C5)alkyl, substituted (C1-C10)alkyl, substituted (C1-C10)heteroalkyl or substituted aryl(C1-C5)alkyl or R2 and R3 may be joined together form a cyclic moiety; R4 is OH or NH2; R5 and R6 each is, independently, H, (C1-C10)alkyl, or R5 and R6 may be joined together form a cyclic moiety; R7 and R8 each is, independently, H, (C1-C10)alkyl, (C1-C10)heteroalkyl, aryl(C1-C5)alkyl, substituted (C1-C10)alkyl, substituted (C1-C10)heteroalkyl or substituted aryl(C1-C5)alkyl; or R7 and R 8 may be joined together form a cyclic moiety; R 9 is H, (C 1 -C 10 )alkyl or substituted (C 1 -C 10 )alkyl; and n is 0 ; or a pharmaceutically acceptable salt thereof.