Patent ID: 7235552

Claim:
Compounds which have a formula (I) in which: R 1 represents a hydroxyl group or a hydroxyl group substituted with a metabolically labile O-protecting group, R 2 represents a hydrogen atom and a double bond is present at c, or R 1 and R 2 together represent an oxo group and a double bond is present at b or double bonds are present at a and b; R 3 represents a methyl group having α- or β-configuration; R 4 and R 5 together with the nitrogen atom to which they are attached form a morpholino or thiamorpholino group; and X represents a group of formula —CH 2 —(CH═CH 2 ) m —(CH 2 ) n — where m is 0, 1 or 2 and n is 0 or an integer such that 2m+n=1, 2, 3 or 4, or a group of formula —(CH 2 ) p —O—(CH 2 ) q — where p is 0, 1, 2 or 3, q is 1, 2, 3 or 4 and p+q does not exceed 4, with the proviso that when R 3 is α-CH 3 and X is (CH 2 ) 3 then R 4 R 5 — is not morpholino.