Patent ID: 7671065

Claim:
A compound of formula (I) wherein a is 1; L 1 is selected from the group consisting of —C(O)— and CH(OH)—; b is an integer from 0 to 2; R 1 is selected from the group consisting of halogen, alkyl, halogenated alkyl, hydroxyl substituted alkyl, alkoxy, cyano, alkyl-carbonyl-, alkoxy-carbonyl-, formyl and phenyl; L 2 is selected from the group consisting of —C(O)—, —CH(OH)— and —CH 2 —; alternatively, L 1 and L 2 are taken together to form a 5-membered oxygen containing ring; R 2 is selected from the group consisting of hydroxy, alkyl, trifluoromethyl, aryl and t-butyl-dimethyl-silyloxy; wherein the aryl is optionally substituted with one or more substituents independently selected from halogen, alkyl, alkoxy, alkylthio-, amino, alkylamino or dialkylamino; provided that when R 2 is hydroxy, then L 1 and L 2 are taken together to form a 5-membered oxygen containing ring; provided further that when a is 1, L 1 is —CH(OH)—, b is 1, R 1 is CF 3 and L 2 is CH 2 , then R 2 is other than alkyl; provided further that when a is 1, L 1 is —C(O)—, b is 1, R 1 is alkoxy and L 2 is —CH(OH)—, then R 2 is other than hydrogen; provided further that when a is 1, L 1 is —C(O)—, b is an integer from 0 to 1, R 1 is halogen, alkoxy, CF 3 or amino and L 2 is—CH 2 —, then R 2 is other than alkyl; or a pharmaceutically acceptable salt thereof.