Patent ID: 6855720

Claim:
A compound of the formula: wherein R is R a R b N—(CH 2 ) m , m is an integer from 1-10, and each of R a and R b is independently phenyl optionally substituted with from one to five substituents independently selected from the group consisting of halo, lower alkyl, lower alkoxy, hydroxy, cyano, nitro, amino, halogenated lower alkyl, halogenated lower alkoxy, formyl, lower alkyl carbonyl, hydroxycarbonyl, lower alkylcarbonyloxy, benzyloxy, optionally substituted piperidino, lower alkoxycarbonyl, and lower alkylcarbonylamino; cycloalkyl of 3-7 carbons, optionally substituted with one to five substituents independently selected from the group consisting of halo, lower alkyl, lower alkoxy, hydroxy, cyano, nitro, amino, halogenated lower alkyl, halogenated lower alkoxy, hydroxycarbonyl, lower alkoxycarbonyl, lower alkylcarbonyloxy, and lower alkylcarbonylamino; lower alkoxy; or R a R b together with N form a cyclic amine or imide ring; and R 2 is —CH 2 NR 7 R 8 (where R 7 and R 8 together with N are cyclic amino), butoxyiminomethyl, hydrogen, or together with R 3 is —CH 2 (NR 12 R 13 )—CH 2 —CH 2 — (where R 12 and R 13 each is independently hydrogen or lower alkyl); R 3 is hydrogen, trialkylsilylethylene or together with R 2 is —CH 2 (NR 12 R 13 )—CH 2 —CH 2 — (where R 12 and R 13 each is independently hydrogen or lower alkyl); R 4 is hydrogen, lower alkyl or together with R 5 is ethylenedioxy; R 5 is hydrogen, halo or together with R 4 is ethylenedioxy; and R 6 is hydrogen, wherein: if R 2 is —CH 2 NR 7 R 8 (where R 7 and R 8 taken together with —N— represent a cyclic amino) then R 3 and R 6 are H and R 4 and R 5 taken together represent ethylenedioxy; if R 2 is butoxyiminomethyl then each of R 3 , R 4 , R 5 and R 6 is H; if R 2 is hydrogen then R 3 is trialkylsilylethylene and each of R 4 , R 5 , and R 6 is H; and if R 2 and R 3 together represent —CH(NR 12 R 13 )—CH 2 —CH 2 — then R 4 is lower alkyl, R 5 is halo, and R 6 is H, wherein R 12 and R 13 each is independently H or lower alkyl.