Patent ID: 7390671

Claim:
A method of magnetic resonance analysis of at least one type of macromolecules present in a solvent, the method comprising: (a) applying a first radiofrequency pulse sequence selected so as to initially select a coherence of an order n for the at least one type of macromolecules in the solvent, wherein n is zero, a positive or a negative integer other than ±1, and thereafter to select an exclusive excitation of the at least one type of macromolecules in the solvent; (b) applying a second radiofrequency pulse sequence which comprises a radiofrequency-free magnetization transfer period so as to generate conditions for maintaining said exclusive excitation of the at least one type of molecules over said magnetization transfer period, said magnetization transfer period being sufficient to allow magnetization transfer from the at least one type of macromolecules to the solvent; (c) measuring at least one magnetic resonance parameter of the solvent; and (d) using said at least one magnetic resonance parameter of the solvent for calculating at least one magnetic resonance parameter of the at least one molecule.