Patent ID: 7358373

Claim:
A compound of the Formula: or pharmaceutically acceptable salt thereof, wherein m is an integer from 1 to 3; n is 0 or 1; Ar 1 is 1-methyl-indol-2-yl, indol-2-yl, indol-5-yl or benzothiazolyl; R 1 is alkylene; each of R 2 , R 3 and R 5 is independently hydrogen or alkyl; and R 4 is aralkyl, cycloalkyl, or —CH(R 6 )—Z 1 , wherein R 6 is hydrogen, or alkyl; Z 1 is —(CR 7 R 8 ) p —X 1 , wherein p is 1 or 2; X 1 is —OR 10 or —NR 10 R 11 ; wherein R 10 is hydrogen, alkyl or heteroalkyl; and R 11 is hydrogen, acetyl, alkyl, aryl, aralkyl, —S(O) x Ar 2 , hydroxy, alkoxy, aralkoxy, —C(O)-aryl, —C(O)—O-aralkyl, or heteroalkoxy, wherein x is an integer from 0 to 2; and Ar 2 is aryl; each R 7 is independently hydrogen or alkyl; each R 8 is independently hydrogen, alkyl, hydroxy, alkoxy, hydroxyalkyl, alkoxyalkyl or aryl; or Z 1 is —(CR 9 )═X 2 ; wherein X 2 is O or NR 12 ; wherein R 12 is hydrogen, alkyl, alkoxy, aralkoxy, hydroxyalkyl, alkoxyalkyl, hydroxy, or —NH—C(═X 3 )—R 13 , wherein X 3 is O or S; and R 13 is alkyl, aryl, arylamino, or aralkylamino; and R 9 is hydrogen, alkyl, hydroxy, alkoxy, aralkoxyalkyl, heteroalkyl, heteroalkylamino, aryl, or arylamino.