Patent ID: 7662836

Claim:
A compound of formula: where X is C(O)NHCH 2 , NHC(O) or NHC(O)CH 2 ; R a is H, NH 2 C(O), CH 3 C(O)NH, CH 3 SO 2 , CH 3 SO 2 NH, linear or branched C 1 -C 3 alkyl, linear or branched C 1 -C 3 alkoxy, or halogen; R b is H, linear or branched C 1 -C 6 alkyl; aryl-(C 1 -C 3 )alkyl optionally substituted with 1 or 2 halogen atoms, with a C 1 -C 3 alkyl group or a C 1 -C 3 alkoxy group; and in which a) when X is C(O)NHCH 2 R c is hydroxy, amino, di-(C 1 -C 3 )alkyl-amino, tri-(C 1 -C 3 )alkyl-ammoniomethyl, nitro, trifluoromethyl, nitrile, CH 3 C(O)NH, CH 3 SO 2 NH, CH 3 SO 2 , R′R″NSO 2 , where R′ and R″ are H, or a linear or branched C 1 -C 6 alkyl, R d is H, hydroxy, amino, di-(C 1 -C 3 )alkyl-amino, tri-(C 1 -C 3 )alkylammoniomethyl, nitro, trifluoromethyl, nitrile, CH 3 C(O)NH, CH 3 SO 2 NH, CH 3 SO 2 , R′R″NSO 2 , where R′ and R″ have the meanings stated above, with the proviso, however, that when R a and R d are both H, and R b is isopropyl, then R c is not hydroxy; b) when X is NHC(O) or NHC(O)CH 2 R c and R d , which may be equal or different, are H, hydroxy, C 1 -C 3 alkoxy, halogen, amino, di-(C 1 -C 3 )alkylamino, tri-(C 1 -C 3 )alkylammoniomethyl, nitro, trifluoromethyl, nitrile, CH 3 C(O)NH, CH 3 SO 2 NH, CH 3 SO 2 , R′R″NSO 2 , where R′ and R″ have the meanings stated above, or an acid addition salt thereof with a pharmaceutically acceptable organic acid or inorganic acid.