Patent ID: 8119681

Claim:
A compound of Formula I or a pharmaceutically acceptable salt thereof, wherein is an optional double bond; A and B are independently selected from the group consisting of: H and F; C, D and E are independently selected from the group consisting of: H, F, —CH 3 and —CF 3 ; F is selected from the group consisting of: a bond, —C(R 1 )(R 2 )— and —C(R 1 )(R 2 )—C(R 3 )(R 4 )—; G is selected from the group consisting of: —O—C(O)—N(R)(R), —O—C(O)—O—R, —C(O)—R, —C(O)—O—R, —C(O)—N(R)(R), —C(O)—N(R)—C(R a )(R b )—R, —C(O)—N(R)—C(R a )(R b )—C(O)—OR, —C(O)—N(R)—C(R a )(R b )—C(O)—NRR, —N(R)—C(O)—R, —N(R)—C(O)—OR, —N(R)—C(O)—N(R)(R), —N(R)—S(O) n —X, —S(O) n —N(R)(R), and —N(R)—S(O) n —N(R)(R), wherein n is 0, 1 or 2; each R is independently selected from the group consisting of: H, haloC 1-8 alkyl, C 2-8 alkenyl, haloC 2-8 alkenyl, C 1-8 alkoxy and C 3-6 cycloalkyl-C 1-4 alkyl-, and two R groups attached to the same nitrogen atom can be joined together with the nitrogen atom to which they are attached to form a 3- to 7-membered monocyclic ring, said ring optionally substituted with oxo and said ring further optionally substituted with 1 to 3 substituents independently selected from the group consisting of: halo, hydroxyl, C 1-4 alkyl and C 1-4 alkoxy; X is selected from the group consisting of: H, C 1-8 alkyl, haloC 1-8 alkyl, C 2-8 alkenyl, haloC 2-8 alkenyl, C 1-8 alkoxy, C 3-6 cycloalkyl, C 3-6 cycloalkyl-C 1-4 alkyl-, —CH 2 —S(O) k —CH 3 , wherein k is 0, 1 or 2, aryl, substituted aryl, heteroaryl and substituted heteroaryl; R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of: H, C 1-4 alkyl, C 1-4 haloalkyl and hydroxy, and R 1 and R 2 may be joined together with the carbon atom to which they are attached to form a 3- to 6-membered mono-cyclic ring; R a and R b are independently selected from the group consisting of: H, C 1-4 alkyl, C 1-4 haloalkyl and hydroxy or R a and R b may be joined together with the carbon atom to which they are attached to form a 3- to 6-membered mono-cyclic ring; and substituted aryl and substituted heteroaryl mean aryl and heteroaryl respectively, each substituted with one to three substituents independently selected from the group consisting of: halo, C 1-4 alkyl, C 1-4 haloalkyl and —CN.