Patent ID: 8193164

Claim:
A compound or stereoisomers or pharmaceutically acceptable salts thereof, wherein the compound is of formula (Ia): wherein U 1 and U 2 are independently selected from CH 2 and O with the proviso that when U 1 is O then R 1a is not a N-bonded substituent, and when U 2 is O then R 1b is not a N-bonded substituent; R 1a and R 1b are independently selected from a 3- to 12-membered heterocyclic group containing from 1 to 4 ring nitrogen atoms and optionally containing from 1 to 4 other heteroatoms selected from the group consisting of oxygen and sulfur, that group being optionally substituted by C 1 -C 8 -alkyl, or R 1a and R 1b are independently selected from —NH—C 1 -C 8 -alkylcarbonyl, and —NH—C 3 -C 8 -cycloalkylcarbonyl, or R 1a and R 1b are independently selected from NH—C 1 -C 8 -alkyl, NHC(O)C 1 -C 8 -hydroxyalkyl, NHCO 2 C 1 -C 8 -alkyl, and NHCO 2 C 1 -C 8 -hydroxyalkyl; T 1a and R 1b are independently selected from C 1 -C 8 -hydroxyalkyl, and CH 2 —O—C 1 -C 8 -alkyl; R 2a and R 2b are independently selected from hydrogen, C 1 -C 8 -alkyl optionally substituted by OH, C 3 -C 15 -carbocyclic group, or C 6 -C 10 -aryl optionally substituted by OH, halogen, or O—C 1 -C 8 -alkyl, or R 2a and R 2b are independently C 7 -C 14 -aralkyl optionally substituted by OH, halogen, or CN; and L is selected from