Patent ID: 7670686

Claim:
A long-term hydrophilic surface modification structure of PDMS comprising: a PDMS substrate with a surface; an amphiphilic polymer layer deposited on said surface, and said amphiphilic polymer having a hydrophobic functional group and a reactive functional group, said reactive functional group of said amphiphilic polymer comprises a carboxyl, aldehyde or ester functional groups, and the amphiphilic polymers comprising hydrolyzed polystyrene maleic anhydride (h-PSMA) which fabricated by hydrolyzing the anhydride groups of polystyrene maleic anhydride to produce carboxylate groups; and a cross-linked stacking layer disposed on said amphiphilic polymer layer, and said cross-linked stacking layer comprising at least a thin layer having a positively charged functional group and at least a thin layer having a negatively charged functional group stacked alternately from the bottom; wherein a plurality of covalent bonds are formed between said amphiphilic polymer layer, said cross-linked stacking layer and the layers in said cross-linked stacking layer by the reactions of said reactive functional group, said positively charged functional group and said negatively charged functional group.