Patent ID: 6979693

Claim:
A compound selected from the group of compounds represented by Formula (I): wherein: R 1 is hydrogen or acyl; R 2 is hydrogen or alkyl; A and B are simultaneously an aryl or a heteroaryl ring; R 3 is selected from the group consisting of: (a) optionally substituted heterocyclyl; (b) heteroalkenyl; (c) heteroalkynyl; (d) optionally substituted heterocyclylalkyl; (e) optionally substituted heterocyclylalkenyl; (f) optionally substituted heterocyclylalkynyl; (g) optionally substituted heterocyclylalkoxy, cyclyloxy or heterocyclyloxy; (h) optionally substituted heterocyclylalkylamino; (i) optionally substituted heterocyclylalkylcarbonyl; (j) —Y-(alkylene)-R 9 where: Y is a single bond, —O—, —NH— or —S(O) n — (where n is an integer from 0 to 2); and R 9 is cyano, optionally substituted heteroaryl, —COOH, —COR 10 n — CONR 12 R 13 , —SO 2 R 14 , —SO 2 NR 15 R 16 , —NHSO 2 R 17 or —NHSO 2 NR 18 R 19 , where R 10 is optionally substituted heterocyclic, and R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 and R 19 are, independently of each other, hydrogen, alkyl or heteroalkyl; (k) —C(═NR 20 )(NR 21 R 22 ) where R 20 , R 21 and R 22 independently represent hydrogen, alkyl or hydroxy, or R 20 and R 21 together are —(CH 2 ) n — where n is 2 or 3 and R 22 is hydrogen or alkyl; (l) —NHC(X)NR 23 R 24 where X is —O— or —S—, and R 23 and R 24 are, independently of each other, hydrogen, alkyl or heteroalkyl; (m) —CONR 25 R 26 where R 25 and R 26 independently represent hydrogen, alkyl, heteroalkyl or optionally substituted heterocyclylalkyl, or R 25 and R 26 together with the nitrogen to which they are attached form an optionally substituted heterocyclyl ring; (n) cycloalkylalkyl and cycloalkylalkynyl, all optionally substituted with alkyl, halo, hydroxy or amino; (o) arylaminoalkylene or heteroarylaminoalkylene; (p) Z-alkylene-NR 30 R 31 or Z-alkylene-OR 32 where Z is —O—, and R 30 , R 31 and R 32 are independently of each other, hydrogen, alkyl or heteroalkyl; (q) —OC(O)-alkylene-CO 2 H or —OC(O)—NR′R″ (where R′ and R″ are independently hydrogen or alkyl); (r) heteroarylalkenylene or heteroarylalkynylene; and (s) heteroalkylamino; R 4 is selected from the group consisting of: (a) hydrogen; (b) halo; (c) alkyl; (d) alkoxy; and (e) hydroxy; R 5 is selected from the group consisting of: (a) hydrogen; (b) halo; (c) alkyl; (d) haloalkyl; (e) thioalkyl; (f) hydroxy; (g) amino; (h) alkylamino; (i) dialkylamino; (j) heteroalkyl; (k) optionally substituted heterocycle; (l) optionally substituted heterocyclylalkyl; (m) optionally substituted heterocyclylalkoxy; (n) alkylsulfonyl; (o) aminosulfonyl, mono-alkylaminosulfonyl or di-alkylaminosulfonyl; (p) heteroalkoxy; and (q) carboxy; R 6 is selected from the group consisting of: (a) hydrogen; (b) halo; (c) alkyl; and (d) alkoxy; and prodrugs, individual isomers, mixtures of isomers and pharmaceutically acceptable salts thereof.