Patent ID: 7977352

Claim:
A compound according to formula III: wherein R 1 represents H, halogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, CF 3 , CN, heterocycloalkyl, unsubstituted, or substituted with C 1 -C 6 alkyl, C 1 -C 8 cycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, carboxamido, cyano, or halo, cycloalkyl, unsubstituted, or substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, carboxamido, cyano, or halo, monocyclic aryl, unsubstituted, or substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, carboxamido, cyano, or halo, monocyclic heteroaryl, unsubstituted, or substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, carboxamido, cyano, or halo, C(═NH)NR a R b , —COR a , —OR a , —OC(O)—C 1 -C 6 alkyl, (CH 2 ) a COOR a , C(O)NR a R b , S(O) 2 (CH 2 ) a N(R a R b ), SR a , SO(CH 2 ) a NR a R b , S(O) 2 —R a , SOR a , (CH 2 ) a NR a R b , (CH 2 ) a N(R a )S(O) 2 —C 1 -C 6 alkyl, (CH 2 ) a NR a S(O)—C 1 -C 6 alkyl, NR a CO—R b , and NH—CO—CO—OR a ; each of which may be optionally substituted with one or more groups selected from H, halogen, OH, C 1 -C 6 alkyl, NH 2 , N(C 1 -C 6 alkyl)(C 1 -C 6 alkyl), heterocycloalkyl, cycloalkyl and CF 3 ; R 2 is selected from heteroaryl, unsubstituted, or substituted with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, cyano, or halo; R 3 , R 4 and R 5 are independently selected from H, OH, OMe, OC 2 H 5 , F, Cl, Me, Et, SO 2 Me, CF 3 and OCF 3 ; CY—R 1 is the subscript n1 is 1, 2, 3, or 4; and each R 1b is independently selected from hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, cyano, and halo; R a and R b each independently represent H, halogen, C 1 -C 6 alkyl, (CH 2 ) a —N(C 1 -C 6 alkyl)(C 1 -C 6 -alkyl), (CH 2 ) a -monocyclic aryl, (CH 2 ) a -monocyclic heteroaryl, (CH 2 ) a -cycloalkyl or (CH 2 ) a -heterocycloalkyl, each of which may be optionally substituted with one or more groups selected from halogen, —OH, C 1 -C 6 alkyl, C 1 -C 6 alkyl-O—C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —NH 2 , —NR c R d , NR c COR d , heteroaryl, heterocycloalkyl, or —CF 3 ; or R a and R b may, if joined to the same atom, represent together with the nitrogen to which they are attached a heterocycloalkyl group which may be optionally substituted with one or more groups selected from halogen, —OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —NH 2 , —NR c R d , —NR c COR d , —C(O)NR c R d , aryl, aralkyl, heteroaryl, cycloalkyl or —CF 3 ; R c and R d each independently represent H, or C 1 -C 6 alkyl; and “a” is 0, 1, 2 or 3; or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof.