Patent ID: 7189724

Claim:
A compound according to Formula 1 wherein Z is NH or O; X is selected from OH, NH 2 , OR, NHR, NRR, SH, or SR; R 1 and R 2 are independently selected from -substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, fused aryl, heterocycle or fused heterocycle, and R 1 and R 2 together with the carbon atoms to which they are attached may form a 5- or 6-membered ring; R 3 is substituted or unsubstituted, alkenyl, alkynyl, aryl, fused aryl, heterocycle or fused heterocycle; and R and R 4 are independently H, or substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, fused aryl, heterocycle or fused heterocycle; wherein each heterocycle is independently a 5- or 6-membered heterocyclic ring containing at least one atom of S, N, or O, and wherein substituted groups are substituted with one or more substituents selected from the group consisting of NH 2 , OH, SH, NC, C(O)OR, aryl, alkyl, alkenyl, alkynyl, F, Cl, Br, NHCOR, NHCONH 2 , NHCSNH 2 , OCH 2 COOH, OCH 2 CONH 2 , OCH 2 CONHR, OC(Me) 2 COOH, OC(Me) 2 CONH 2 , NHCH 2 COOH, NHCH 2 CONH 2 , NHSO 2 R, NHSO 2 CF 3 , PO 3 H, SO 3 H, (CH 2 ) 1-3 COOH, CH═CHCOOH, O(CH 2 ) 1-4 COOH, NHCOCH 2 CH(OH)COOH, CH(COOH) 2 , CH(PO 3 H) 2 , OCH 2 CH 2 CH 2 COOH, and NHCHO.