Patent ID: 7307166

Claim:
A compound having the formula: wherein R A , R B and R D are the same, or different, and are hydrogen or I. an acyl group derived from a. an unbranched fatty acid with 6 to 22 carbon atoms, optionally substituted at the terminal carbon with a hydrophilic moiety selected from the group consisting of NH 2 , OH, OPO 3 = , PO 3 = , OSO 3 − , and SO 3 − , b. an amino acid selected from the group consisting of glycine, the L forms of phenylalanine, alanine, valine, leucine, isoleucine, tyrosine, proline, hydroxyproline, serine, threonine, cysteine, aspartic acid, glutamic acid, arginine, lysine, histidine and ornithine, c. an unbranched alkylene dicarboxylic acid having 3-22 carbon atoms, d. nicotinic acid, e. a cycloalkyl carboxylic acid containing 4 to 22 carbon atoms, f. a carboxylic acid derived from i. a polymer of ethylene glycol with the structure HOOC—(CH 2 ) m —(CH 2 CH 2 O) n H or HOOC—(CH 2 ) m —(CH 2 CH 2 O) n CH 3 , or ii. a polymer of vinyl alcohol with the structure HOOC—(CH 2 ) m —(CH 2 CHOH) n H or HOOC—(CH 2 ) m —(CH 2 CHOH) n CH 3 , where m=0-3 and n=2-8, or II. an unbranched alkyl radical with 3 to 22 carbon atoms, optionally substituted at the terminal carbon with a hydrophilic moiety selected from the group consisting of NH 2 , OH, OPO 3 = , PO 3 = , OSO 3 − , SO 3 − , provided that not all of the R A , R B , and R D are hydrogen, and Q=a halogen, NHR F , where R F is H or an alkyl radical or an acyl radical of a carboxylic acid, said radicals each containing 1 to 10 carbon atoms, SR G where R G is H or an alkyl radical or an acyl radical of a carboxylic acid, said radicals each containing 1 to 10 carbon atoms, or OR H where R H is H or an alkyl radical or an acyl radical of a carboxylic acid, said radicals each containing 1 to 10 carbon atoms, and Z is H, OH, or NHR C where R C ═H or an acyl radical of a carboxylic acid with 2 to 30 carbon atoms or an alkyl radical with 2 to 30 carbon atoms; or a pharmaceutically acceptable salt thereof.