Patent ID: 8182864

Claim:
A method for modification of microchannels of a polydimethylsiloxane (PDMS) microchip, which comprises the steps of: a) preparing a sol-gel solution consisting of an alkoxysilane precursor of the following Chemical Formula 1, an alkyl alkoxysilane precursor of the following Chemical Formula 2, a solvent, and an acid catalyst selected from the group consisting of hydrochloric acid and sulfuric acid; b) oxidizing microchannels of the PDMS microchip; and c) coating the oxidized microchannels with the sol-gel solution prepared in step a), (R 1 O) 4 —Si [Chemical Formula 1] (wherein R 1 is C 1 -C 3 alkyl), and (R 2 ) n —Si—(OR 3 ) 4-n [Chemical Formula 2] (wherein R 2 and R 3 are independently a C 1 to C 2 alkyl, and n is 1 or 2), wherein the modified PDMS microchip is hydrophilic.