Patent ID: 8188287

Claim:
A compound of Formula I, wherein: R 1 is phenyl, naphthyl, heteroaryl, or partially saturated benzofused heteroaryl, wherein the phenyl, naphthyl, heteroaryl, or partially saturated benzofused heteroaryl may be optionally substituted with up to three substituents selected from the group consisting of —F, —Cl, —CF 3 , —CN, —C (1-4) alkyl, —C (1-4) alkylOH, —C (1-4) alkylNH 2 , —C (1-4) alkylNHC (1-4) alkyl, —C (1-4) alkylN(C (1-4) alkyl) 2 , —NO 2 , —NHC (1-4) alkyl, —CONHC (1-4) alkyl, —SO 2 NHC (1-4) alkyl, —OC (1-4) alkyl, —NH 2 , —CONH 2 , —SO 2 NH 2 , —NHCOCH 3 , and —OH; R 2 is H, —C (1-4) alkyl, or —C (1-4) alkyl-OH, wherein said —C (1-4) alkyl and said —C (1-4) alkyl-OH are optionally substituted with —OH, —NH 2 , —F, —Cl, heteroaryl, or phenyl; X is a direct bond, or CHCO 2 H; R 3 is —F, —Cl, —CF 3 , —CN, —C (1-4) alkyl, —C (1-4) alkylOH, —C (1-4) alkylNH 2 , —C (1-4) alkylNHC (1-4) alkyl, —C (1-4) alkylN(C (1-4) alkyl) 2 , —NO 2 , —NHC (1-4) alkyl, —CONHC (1-4) alkyl, —SO 2 NHC (1-4) alkyl, —OC (1-4) alkyl, —NH 2 , —CONH 2 , —SO 2 NH 2 , —NHCOCH 3 , or —OH; R 4 is —F, —Cl, —OCH 3 , or may be taken together with an adjacent R 3 to form a methylidene acetal; and R 5 is —F, Cl, or —OCH 3 ; and pharmaceutically acceptable salts thereof.