Patent ID: 8093389

Claim:
A compound represented by a general formula (I-2): wherein, Ar 1 represents a group formed from an aromatic ring selected from a group consisting of indole, 1H-indazole, 2H-indazole, 1H-thieno[2,3-c]pyrazole, 1H-pyrazolo[3,4-b]pyridine, benzo[b]furan, benzimidazole, benzoxazole, 1,2-benzisoxazole and imidazo[1,2-a]pyridine, having R 30 and R 40 , and optionally having a substituent selected from a group consisting of a halogen atom, a nitro group, a cyano group, a hydroxyl group, a C1-C6 alkyl group, a halo-C1-C6 alkyl group, a hydroxy-C1-C6 alkyl group, a cyclo-C3-C6 alkyl group, a C2-C6 alkenyl group, a C1-C6 alkoxy group, a halo-C1-C6 alkoxy group, a C1-C6 alkylthio group, a carboxyl group and a carbamoyl group; R 1 represents an aryl or heterocyclic group optionally having a substituent selected from a group consisting of a halogen atom, a hydroxyl group, an oxo group, a thioxo group, a C1-C6 alkyl group, a halo-C1-C6 alkyl group, a hydroxy-C1-C6 alkyl group, a C2-C7 alkanoyloxy-C1-C6 alkyl group, a C1-C6 alkoxy group, a halo-C1-C6 alkoxy group, a formyl group, a carboxyl group, a C2-C7 alkanoyl group, a C2-C7 alkoxycarbonyl group, a C1-C6 alkylsulfonyl group and a group of —CO—N(R c )R d ; or a C1-C6 alkyl group or a C2-C6 alkenyl group having the aryl or heterocyclic group; R 20 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group, or a C1-C6 alkoxy group; R 30 and R 40 each independently represent a halogen atom, a nitro group, a cyclo-C3-C6 alkyl group, a carbamoyl group optionally substituted with a C1-C6 alkyl or cyclo-C3-C6 alkyl group, or a group of —N(R e )R f ; or a C2-C7 alkanoyl group, a C1-C6 alkoxy group, a C2-C7 alkoxycarbonyl group, a cyclo-C3-C6 alkyloxycarbonyl group, a C1-C6 alkylsulfonyl group, a C1-C6 alkylthio group, a cyclo-C3-C6 alkyloxy group, a cyclo-C3-C6 alkyl-C1-C6 alkoxy group, a cyclo-C3-C6 alkylsulfonyl group, a cyclo-C3-C6 alkylthio group or a cyclo-C3-C6 alkyl-C1-C6 alkylthio group, optionally substituted with a halogen atom or a hydroxyl group, wherein the cyclo-C3-C6 alkyl group in the cyclo-C3-C6 alkyloxycarbonyl group, the cyclo-C3-C6 alkyloxy group, the cyclo-C3-C6 alkyl-C1-C6 alkoxy group, the cyclo-C3-C6 alkylsulfonyl group, the cyclo-C3-C6 alkylthio group or the cyclo-C3-C6 alkyl-C1-C6 alkylthio group may be interrupted by an oxygen atom, a sulfur atom or an imino group; or a C1-C6 alkyl group optionally having a substituent selected from a group consisting of a halogen atom, a hydroxyl group and a cyclo-C3-C6 alkyl group; R c and R d each independently represent a hydrogen atom, a C1-C6 alkyl group, or a halo-C1-C6 alkyl group; and R e and R f each independently represent a hydrogen atom, a C1-C6 alkyl group, or a halo-C1-C6 alkyl group, or taken together, they may form a C2-C5 alkylene group optionally interrupted by an oxygen atom, a sulfur atom or an imino group; or a pharmaceutically acceptable salt.