Patent ID: 8691942

Claim:
A peptide selected from the group having the formulae: [A 0 -Tyr 1 , D-Arg 2 , A 4 , A 6 , A 8 , Har 9 , Tyr(Me) 10 , A 11 , A 12 , Abu 15 , A 17 , A 20 , A 21 , Nle 27 , D-Arg 28 , A 29 -A 30 -A 31 ]hGH-RH(1-29)NH 2 wherein A 0 is PhAc, N-Me-Aib, Dca, Ac-Ada, Fer, Ac-Amc, Me-NH-Sub, PhAc-Ada, Ac-Ada-D-Phe, Ac-Ada-Phe, Dca-Ada, Dca-Amc, Nac-Ada, Ada-Ada, or CH 3 —(CH 2 ) 10 —CO-Ada, A 4 is Ala or Me-Ala, A 6 is Cpa or Phe(F) 5 , A 8 is Ala, Pal, or Me-Ala, A 11 is His or Arg, A 12 is Lys, Lys(0-11), Lys(Me) 2 or Orn, A 17 is Leu or Glu, A 20 is Har or His, A 21 is -Lys, Lys(Me) 2 or Orn, A 29 is Har, Arg or Agm, A 30 is absent, β-Ala, Amc, Apa, Ada, AE 2 A, AE 4 P, ε-Lys(α-NH 2 ) or Agm, A 31 is absent, Lys(Oct) or Ahx, provided that where A 0 is PhAc, A 12 and A 21 are both other than Orn and A 30 is not absent and is not Agm, and pharmaceutically acceptable salts thereof.