Patent ID: 7411091

Claim:
A compound of general formula I wherein A is a straight or branched C 2 -C 8 alkyl chain; X is a methylene, oxygen, sulphur or a NR 7 group; R 1 is a straight or branched C 1 -C 8 alkyl or C 3 -C 8 alkenylene or C 3 -C 8 alkynylene chain, optionally substituted with CF 3 , phenyl, phenoxy or naphthyl, the aromatic rings optionally substituted by one or more C 1 -C 4 alkyl, halogens, trifluoromethyl, hydroxy or C 1 -C 4 alkoxy groups; R 2 , R 3 are independently hydrogen, a C 1 -C 3 alkyl chain, halogen, trifluoromethyl, hydroxy or C 1 -C 4 alkoxy groups; R 4 , R 5 are independently hydrogen or C 1 -C 6 alkyl; R 6 is a hydrogen or a straight or branched C 1 -C 8 alkyl or linked to R 5 can form a five to seven membered lactam; R 7 is hydrogen or C 1 -C 6 alkyl; and the pharmaceutically acceptable salts thereof, with the proviso that when A is —CH 2 CH 2 —, R 1 -X is ortho-benzylthio, R 2 , R 3 and R 5 are hydrogen and R 6 methyl, R 4 is other than hydrogen or methyl; when A is —CH 2 CH 2 —, R 1 —X 4-methoxy, R 2 2-methoxy, R 3 and R 5 hydrogen and R 6 methyl, R 4 is other than hydrogen, and when A is —CH 2 CH 2 —, R 1 —X 3-methoxy, R 2 5-methoxy, R 3 and R 5 hydrogen and R 6 methyl, R 4 is other than hydrogen.