Patent ID: 8802150

Claim:
A polymeric hollow nanosphere for release of an agent, wherein said hollow nanosphere comprises at least one natural or synthetic biodegradable polymer, selected from the group consisting of: collagen, elastin, chitosan, hyaluronan, alginate, peptides amphiphiles, polyesters, and combinations thereof, wherein said at least one polymer is cross-linked by a cross-linker agent selected from the group consisting of: a dendrimer, a hyper-branched dendritic polymer and linear polymeric system; characterised in that the reactive groups in the cross-linking agent are —COOH or NH 2 groups and the reactive groups in said polymer are —NH 2 or COON groups and molar ratio of reactive groups in said cross-linker agent to reactive groups in said biodegradable polymer is in the range 50:1 to 1:50.