Patent ID: 7927593

Claim:
A monoclonal antibody, or an antigen-binding fragment thereof, that binds TGF-Beta 1, 2, and 3, comprising a heavy chain variable region (HCVR) and a light chain variable region (LCVR), wherein said HCVR comprises a HCVR CDR1 with an amino acid sequence as shown in SEQ ID NO: 100, a HCVR CDR2 with an amino acid sequence as shown in SEQ ID NO: 101, and a HCVR CDR3 with an amino acid sequence as shown in SEQ ID NO: 98, and said LCVR comprises a LCVR CDR1 with an amino acid sequence as shown in SEQ ID NO: 92, a LCVR CDR2 with an amino acid sequence as shown in SEQ ID NO: 89, and a LCVR CDR3 with an amino acid sequence as shown in SEQ ID NO: 90.