Patent ID: 7592335

Claim:
A compound of Formula I, and their pharmaceutically acceptable salts, pharmaceutically acceptable esters, enantiomers, diastereomers, or N-oxides, wherein U and V are selected from hydrogen and fluorine (wherein both U and V cannot simultaneously be hydrogen); A is selected from; R is H, alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, aryl, aralkyl, heteroaryl, heterocyclyl, heteroarylalkyl or heterocyclylalkyl, —COR a , —C(O)OR a , or S(O) 2 R a ; R 1 is azido, halogen, NCS, NHYR f NR j C(=T)NR f R q , NR f R q or NR j (C═O)OR s ( ); R a is selected from hydrogen, straight or branched unsubstituted or substituted alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, aryl, aralkyl, heteroaryl, heterocyclyl, heteroarylalkyl or heterocyclylalkyl; Y is (C═O), (C═S) or SO 2 ; R f is hydrogen, alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, aryl, aralkyl, heteroaryl, heterocyclyl, heteroarylalkyl or heterocyclylalkyl; T is O, S, —N(CN), —N(NO 2 ), or —CH(NO 2 ); R j is hydrogen, alkyl, alkenyl, cycloalkyl, aryl, aralkyl, heterocyclyl, heteroaryl, heteroarylalkyl or heterocyclylalkyl; R q is hydrogen, alkyl, cycloalkyl, aryl, aralkyl, heteroaryl, heterocyclyl, heteroarylalkyl or heterocyclylalkyl, and R s is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl, heteroarylalkyl or heterocyclylalkyl.