Patent ID: 7754708

Claim:
A method of treating depression or anxiety comprising administering a compound of Formula I: wherein: R is H or C 1-10 alkyl; m is 1, 2, 3, or 4; n is 0, 1, or 2; p is 0, 1, 2, or 3; q is 0, 1, 2, 3, or 4; and j is 0, 1, 2, or 3; and the values of m, n, p, and q are selected such that the depicted azaspiro ring contains 6, 7, 8, 9, 10, or 11 members; and when m is 1, n is not 0; and m and n combine such that the depicted aza-containing ring is 4-, 5-, or 6-membered; each Z is, individually, selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl, and substituted arylalkyl; the dashed line represents an optional double bond; Cy is pyridinyl or substituted pyridinyl; wherein the term substituted refers to one or more of a group consisting of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, alkylaryl, arylalkyl, halogen, —OR′, —NR′R″, —CF 3 , —CN, —NO 2 , —C≡CR′, —SR′, —N 3 , —C(═O)NR′R″, —NR′C(═O) R″, —C(═O)OR′, —C(═O)OR′, —OC(═O)R′, —O(CR′R″) r C(═O)R′, —O(CR′R″) r NR″C(═O)R′, —O(CR′R″) r NR″SO 2 R′, —OC(═O)NR′R″, —NR′C(═O)OR″, —SO 2 R′, —SO 2 NR′R″, or —NR′SO 2 R″; each R′ and R″ individually is hydrogen, C 1 -C 8 alkyl, cycloalkyl, heterocyclyl, aryl, or arylalkyl and each r individually is an integer from 1 to 6; or R′ and R″ can combine to form a 3-to 7-membered saturated or unsaturated ring; or a pharmaceutically acceptable salt thereof to a patient in need of treatment thereof.