Patent ID: 6949579

Claim:
A compound of formula (I) wherein R is O, S or NH R3 is (1-6C)alkyl, aryl, aryl(1-6C)alkyl, heteroaryl, heteroaryl(1-6C)alkyl, aryl or heteroaryl fused to a cycloalkyl (1-10C), heterocycle, cycloalkyl, adamantyl, polycycloalkyls, alkenyl, or alkynyl radical; these radicals being optionally substituted with one or more substituents selected from the group consisting of halogen, CN, NO 2 , NH 2 , OH, OR8, COOH, C(O)OR8, —O—C(O)R8, NR8R9, NHC(O)R8, C(O)NR8R9, SR8, S(O)R8, SO 2 R8, NHSO 2 R8, SO 2 NR8R9, C(S)NR8R9, NHC(S)R8, —O—SO 2 R8, —SO 2 —O—R8, aryl, heteroaryl, formyl, trifluoromethyl, trifluoromethylsulphanyl and trifluoromethoxy; R4, R5, R6 and R7 are, independently of each other, selected from the group consisting of hydrogen, halogen, CN, NO 2 , NH 2 , OH, COOH, C(O)OR8, —O—C(O)R8, NR8R9, NHC(O)R8, C(O)NR8R9, NHC(S)R8, C(S)NR8R9, SR8, S(O)R8, SO 2 R8, NHSO 2 R8, SO 2 NR8R9, —O—SO 2 R8, —SO 2 —O—R8, trifluoromethyl, trifluoromethoxy, (1-6C)alkyl, (1-6C)alkoxy, aryl, aryl(1-6C)alkyl, heteroaryl, heteroaryl(1-6C)alkyl, heterocycle, cycloalkyl, alkenyl, alkynyl, adamantyl, and polycycloalkyls; these radicals being optionally substituted with one or more substituents selected from the group consisting of halogen, CN, NO 2 , NH 2 , OH, OR10, COOH, C(O)OR10, —O—C(O)R10, NR10R11, NHC(O)R10, C(O)NR10R11, NHC(S)R10, C(S)NR10R11, SR10, S(O)R10, SO 2 R10, NHSO 2 R10, SO 2 NR10R11, —O—SO 2 R10, —SO 2 —O—R10, aryl, heteroaryl, formyl, trifluoromethyl and trifluoromethoxy; R8, R9, R10, R11 are, independently of each other, selected from the group consisting of hydrogen, (1-6C)alkyl, aryl, alkenyl, alkynyl or heteroaryl, themselves optionally being substituted with one or more substituents chosen from halogen, (1-6C)alkyl, (1-6C)alkoxy, CN, NO 2 , NH 2 , OH, COOH, COOalkyl, CONH 2 , formyl, trifluoromethyl and trifluoromethoxy; or a racemic mixture, an enantiomer, a diastereoisomer or mixtures thereof, or a tautomer thereof, or a pharmaceutically acceptable salt thereof, and with the exception of following compounds: 3-(2-nitrobenzamido)indazole, 3-(2-aminobenzamido)indazole, 3-(4-chloro-2-nitrobenzamido)indazole, 3-(5-chloro-2-nitrobenzamido)indazole, 3-(2-amino-4-chlorobenzamido)indazole, 3-(2-amino-5-chlorobenzamido)indazole, 3-(benzamido)indazole, 3-(4-methylbenzamido)indazole, 3-(4-chlorobenzamido)indazole, 3-(4-nitrobenzamido)indazole, 3-acetamidoindazole, N-(1H-indazol-3-yl)butanamide, N-(1H-indazol-3-yl)phenylacetamide, N-(1H-indazol-3-yl)benzhydrylacetamide, 5-amino-3-acetamidoindazole, 3-(2-hydroxybenzamido)indazole, N-(6-chloro-1H-indazol-3-yl)-2,2,2-trifluoroacetamide, N-(6-chloro-1H-indazol-3-yl)-2-furancarboxamide, N-(6-chloro-1H-indazol-3-yl)-2-thiophenecarboxamide, N-(6-chloro-1H-indazol-3-yl)-4-(hexyloxy)benzamide, 3-chloro-N-(6-chloro-1H-indazol-3-yl)benzamide, 4-chloro-N-(6-chloro-1H-indazol-3-yl)benzamide, and N-(5-nitro-1H-indazol-3-yl)acetamide.