Patent ID: 8134007

Claim:
A compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: R 1 is selected from the group consisting of: (i) phenyl, optionally substituted by one or more substituents each independently selected from the group consisting of halo, cyano, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, halo(C 1 -C 4 )alkyl, halo(C 1 -C 4 )alkoxy, (C 1 -C 4 )alkoxy(C 1 -C 4 )alkyl, (C 1 -C 4 )alkylamino and di-((C 1 -C 4 )alkyl)amino; and (ii) a 5-membered heteroaryl group comprising either (a) from 1 to 4 nitrogen atoms or (b) one oxygen or one sulphur atom and 1 or 2 nitrogen atoms, and wherein the heteroaryl group is optionally substituted by one substituent selected from the group consisting of (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, halo(C 1 -C 4 )alkyl, halo(C 1 -C 4 )alkoxy, (C 1 -C 4 )alkoxy(C 1 -C 4 )alkyl, (C 1 -C 4 )alkylamino and di-((C 1 -C 4 )alkyl)amino; with the proviso that R 1 is not imidazolyl, oxazolyl or 1,2,4-triazolyl; Ar is wherein →indicates the point of attachment to the pyridine ring; each R 2 is independently selected from the group consisting of (C 1 -C 4 )alkyl, OR 4 , (C 1 -C 4 )alkoxy(C 1 -C 4 )alkyl, halo(C 1 -C 4 )alkyl, cyano and halo; n is 0 to 4; m is 0 to 7; p is 0 to 3; R 3 is selected from the group consisting of hydrogen, (C 1 -C 4 )alkyl, OR 4 , (C 1 -C 4 )alkoxy(C 1 -C 4 )alkyl, halo(C 1 -C 4 )alkyl, cyano and halo; R 4 is selected from the group consisting of hydrogen, (C 1 -C 4 )alkyl, halo(C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy(C 1 -C 4 )alkyl, (C 3 -C 6 )cycloalkyl, (C 3 -C 6 )cycloalkyl(C 1 -C 4 )alkyl, Het 1 -, and Het 1 (C 1 -C 4 )alkyl-; and Het 1 is a saturated 5- or 6-membered heterocyclic ring comprising one oxygen atom.