Patent ID: 8530517

Claim:
A compound having the general formula I Wherein R 1 is H, O(CO)OR 4 , NR 4 R 5 , CN, alkyl, cycloalkyl or heterocycloalkyl; wherein alkyl, cycloalkyl and heterocycloalkyl are optionally substituted once or more with C 1 -C 6 alkyl, (CH 2 ) n COR 3 , O(CO)OR 4 , OH or NR 4 R 5 ; n is 0 or 1; R 3 is OH, amino, (C 1 -C 3 )-alkyl-amino or benzyloxy; R 4 and R 5 are the same or different and are each H or alkyl; or R 4 and R 5 taken together with the nitrogen atom to which they are attached form a heterocycloalkyl group; or NR 4 R 5 form a nitro group; R 2 is alkylene, hydroxyalkylene, aminocarbonylalkylene, (C 2 -C 18 )-alkenylene, (C 3 -C 6 )-cycloalkylene, heterocycloalkylene, —(OCH 2 CH 2 ) m —O—, branched or linear polyaminoalkylene, phenyloxy optionally substituted with NO 2 ; or is absent; m is an integer from 1 to 4; A is CH 2 —, —CO—, —CH 2 —(CO)—, —NH(CO)— or —[CO—(CHR 6 )—NH] w —; R 6 is the side chain of a natural amino acid radical; w is 1; or tautomers, geometrical isomers, optically active forms or pharmaceutically acceptable salts thereof; with the proviso that R 1 —R 2 -A does not represent alkyl or alkyl-CO.