Patent ID: 8249323

Claim:
A method for providing quality control assessments in single time-point in-vivo imaging data related to the imaging of objects, the method comprising: acquiring at least one in-vivo image of an object with an imaging apparatus; defining a background image to correspond to an imaged air of the in-vivo image; defining an object image to correspond to the in-vivo image from which the background image has been removed; obtaining the background image and the object image by an atlas-based registration; providing a histogram (H) reflecting an intensity distribution of the background image; fitting a noise mathematical model to at least a part of the intensity distribution of the histogram (H); deriving characteristics of a quality of the background from the noise mathematical model; providing a further histogram (H) reflecting an intensity distribution of the object image; fitting a signal mathematical model to an intensity distribution of the further histogram (H); deriving characteristics of a quality of the object from the signal mathematical model; and automatically deriving a signal-to-noise ratio and a contrast-to-noise ratio of in-vivo imaging data from the characteristics of the quality of the object and from the characteristics of the quality of the background.