Patent ID: 7737136

Claim:
A compound according to Formula I, or a pharmaceutically acceptable salt thereof wherein R1, R3, R4, R5 and R10 independently are selected from the group consisting of H, halogen, (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, OH, CN, O(1-4C)alkyl, S(O) m (1-4C)alkyl, optionally substituted with one or more halogen atoms, C(O)(1-4C)alkyl, OC(O)(1-4C)alkyl and NR19R20, R2 is selected from the group consisting of H, halogen, NO 2 , NR11R12, (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, OH, O(1-4C)alkyl, S(1-4C)alkyl and OC(O)(1-4C)alkyl, R6 is selected from the group consisting of H, C(Y)R15, C(O)OR16, C(S)NR17, (1-6C)alkyl, (1-6C)alkoxy-substituted (1-4C)alkyl and (CH 2 ) n C(O)OR21, R7 is H or R7 is selected from the group consisting of (1-4C)alkyl, (2-4C)alkenyl and (2-4C)alkynyl, all optionally substituted with one or more halogen atoms, R8 and R9 independently are selected from the group consisting of H and (1-4C)alkyl, R11 and R12 independently are selected from the group consisting of H, (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (1-6C)alkoxycarbonyl, (1-4C)alkylsulfonyl, and (6-10C)arylsulfonyl, R15 is H or R15 is selected from the group consisting of (1-6C)alkyl, (3-6C)cycloalkyl, (2-4C)alkenyl or (2-4C)alkynyl, (6-10C)aryl, 1,4-bisaryl, amino(1-4C)alkyl, hydroxyl(1-4C)alkyl, and carboxy(1-4C)alkyl, all optionally substituted with one or more halogen atoms, R16 is (1-6C)alkyl, optionally substituted with one or more halogen atoms, R17 is selected from the group consisting of (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl and (3-6C) cycloalkyl, all optionally substituted with one or more halogen atoms, X is O, Y is selected from the group consisting of O, S, and NH, R18 is selected from the group consisting of H and (1-4C)alkyl, R19 is selected from the group consisting of H and (1-4C)alkyl, R20 is selected from the group consisting of H, (1-4C)alkyl, CH 2 (6-10C)aryl, C(O)(1-6C)alkyl and C(O)NH(1-4C)alkyl, R21 is selected from the group consisting of H and (1-6C)alkyl, m is 0, 1 or 2, and n is 1, 2 or 3, provided that (i) when R1, R2, R3, R4, and R5 are H, R8, R9 and R10 are H, and R6 is ethyl or C(O)CH 3 then R7 is not H; (ii) when R1, R2, R3, R4, and R5 are H, R8, R9 and R10 are H, and R6 is methyl then R7 is not methyl; and (iii) when R1, R2, R3, R4, and R5 are H, R8, R9 and R10 are H, and R6 is H then R7 is not H or ethyl.