Patent ID: 6946479

Claim:
A compound of formula (I) wherein: a) R 1 is aryl optionally substituted with one or more hydrogen, halo, cyano, hydroxy, carboxy, keto, thioketo, amino, acylamino, acyl, amido, phenyl, aryloxy alkyl, alkenyl, alkynyl, heteroalkyl, halo, haloalkyl, alkoxy, aryl, cycloalkyl, spirocycloalkyl and combinations thereof; b) each R 2 is independencly chosen from hydrogen, halo, cyano, hydroxy, carboxy, keto, thioketo, amino, acylamino, acyl, amido, phenyl, aryloxy, alkyl, alkenyl, alkynyl, heteroalkyl, halo, haloalkyl, alkoxy, aryl, and cycloalkyl; c) R 3 and R 4 are each independently chosen from hydrogen, alkyl, alkenyl, alkynyl, heteroalkyl, aryl, cycloalky, alkylheteroalkyl, alkylaryl, and alkylcycloalkyl; and d) R 5 and R 6 are each independently chosen from of hydrogen, halo, cyano, hydroxy, carboxy, keto, thioketo, amino, acylamino, acyl, amido, phenyl, aryloxy, alkyl, alkenyl, alkynyl, heteroalkyl, halo, haloatkyl, alkoxy, aryl, and cycloalkyl; or e) optical isomers, diastereomers and enantiomers of the formula above, and pharmaceutically-acceptable salts, thereof.