Patent ID: 8153791

Claim:
A compound of formula (Ia): or a salt, stereoisomer or tautomer thereof, wherein L is selected from a bond, C 1-6 alkyl or halo-C 1-8 alkyl; R 1 is selected from hydrogen, C 1-8 alkyl, C 1-8 alkenyl, C 1-8 alkoxy, C 1-8 alkoxy-C 1-8 alkyl, hydroxy-C 1-8 alkyl, hydroxy-C 1-8 alkoxy, amino-C 1-8 alkyl, C 1-8 alkyl-amino-C 1-8 alkyl, C 1-8 alkoxy-C 1-8 alkyl-amino-C 1-8 alkyl, C 1-8 alkyl-sulfonyl-C 1-8 alkyl, C 1-8 alkyl-sulfonyloxy-C 1-8 alkyl, aryl, aryl-C 1-8 alkyl, aryloxy-C 1-8 alkyl, heterocyclyl-C 1-8 alkyl, heterocyclyl-carbonyl-C 1-8 alkyl, benzofused-heterocyclyl-C 1-8 alkyl or heteroaryl-C 1-8 alkyl, wherein aryl-C 1-8 alkyl is optionally substituted on aryl with one, two, three, four or five substituents each selected from hydroxy, C 1-8 alkyl, C 1-8 alkoxy, amino, C 1-8 alkyl-amino or C 1-8 alkoxycarbonyl, and wherein heterocyclyl-C 1-8 alkyl is optionally substituted on heterocyclyl with one, two, three or four substituents each selected from hydroxy, C 1-8 alkyl, C 1-8 alkoxy, amino, C 1-8 alkyl-amino or C 1-8 alkoxycarbonyl; R 2 is selected from hydrogen, C 1-8 alkyl or C 1-8 alkoxy; and R 3 , R 4 , R 5 , R 6 and R 7 is each selected from hydrogen, halogen, hydroxy, C 1-8 alkyl, C 1-8 alkoxy, C 1-8 alkoxy-C 1-8 alkyl, hydroxy-C 1-8 alkyl, halo-C 1-8 alkyl, hydroxy-C 1-8 alkoxy, halo-C 1-8 alkoxy, cyano-C 1-8 alkyl, amino, C 1-8 alkyl-amino, amino-C 1-8 alkyl, C 1-8 alkyl-amino-C 1-8 alkyl, C 1-8 alkyl-amino-C 1-8 alkyl-amino-carbonyl, C 1-8 alkoxy-imino-C C 1-8 alkoxy-imino-(aryl)C 1-8 alkyl, carboxy, C 1-8 acyl, C 1-8 acyl-amino, C 1-8 alkoxycarbonyl, thio-C 1-8 alkyl, substituted phosphonic acid, C 3-12 cycloalkyl, aryl, aryloxy, aryl-amino, aryl-C 1-8 alkyl, aryl-C 1-8 alkoxy, aryl-carbonyl-C 1-8 alkyl, aryl-amido, heteroaryl, heteroaryloxy, heteroaryl-C 1-8 alkoxy, heteroaryl-amino-sulfonyl, benzofused-heterocyclyl or heterocyclyl, wherein phosphonic acid is substituted on the phosphorous atom with two substituents selected from hydroxy or C 1-8 alkoxy, wherein aryl, aryl-amino, aryloxy, aryl-C 1-8 alkyl and aryl-C 1-8 alkoxy is each optionally substituted on aryl with one, two, three, four or five substituents each selected from cyano, halogen, hydroxy, C 1-8 alkyl, C 1-8 alkoxy, amino, C 1-8 alkyl-amino, amino-C 1-8 alkyl, C 1-8 alkyl-amino-C 1-8 alkyl or C 1-8 alkoxycarbonyl, wherein benzofused-heterocyclyl is optionally substituted on the heterocyclyl portion with one or two oxo substituents, and wherein heteroaryl, heteroaryl-amino-sulfonyl and heteroaryloxy is each optionally substituted on heteroaryl with one, two, three, four or five substituents each selected from C 1-8 alkyl, amino-C 1-8 alkyl, C 1-8 alkyl-amino-C 1-8 alkyl, carboxy, C 1-8 acyl or C 1-8 alkoxycarbonyl.