Patent ID: 7763644

Claim:
A compound having formula I, geometrical isomers (including cis and trans, Z and E isomers), enantiomers, diastereoisomers and mixtures thereof (including all possible mixtures of stereoisomers), or pharmaceutically acceptable salts thereof, wherein R 1 is hydrogen, C 1-20 alkyl, C 3-8 cycloalkyl, halogen, hydroxy, alkoxy, aryloxy, ester, amido, cyano, nitro, amino, guanidine, amino derivative, alkylthio, arylthio, alkylsulfonyl, arylsulfonyl, alkylsulfinyl, arylsulfinyl, aryl or heterocycle; R 2 and R 3 form together with the imidazole ring the following 1H— benzimidazole cycle R 4 is C 1-20 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, or aryl; R 4a is hydrogen; R 5 is hydrogen; R 6 is hydrogen; R 7 is hydrogen; R 8 is hydrogen, halogen, nitro, cyano, C 1-20 alkyl or alkoxy; R 9 is hydrogen, C 1-20 alkyl, halogen, hydroxy, alkoxy, aryloxy, ester, amido, cyano, nitro, amino, alkylthio, arylthio, alkylsulfonyl, arylsulfonyl, alkylsulfinyl or arylsulfinyl; R 10 is hydrogen, C 1-20 alkyl, halogen, hydroxy, alkoxy, aryloxy, ester, amido, cyano, nitro, amino, alkylthio, arylthio, alkylsulfonyl, arylsulfonyl, alkylsulfinyl or arylsulfinyl; and R 11 is hydrogen, halogen, nitro, cyano, C 1-20 alkyl or alkoxy.