Patent ID: 8204729

Claim:
A device for managing blood glucose concentration comprising: a means for inputting at least two recent past blood glucose concentration data items, each data item comprising a blood glucose concentration value and a time-of-measurement value; a means for inputting insulin delivery data items, each data item comprising an insulin dosage amount and a time-of-delivery value; a means for inputting insulin time-action profile data; a means for inputting patient R BGC/I data, the responsiveness of the patient's blood glucose concentration to insulin, optionally as a function of time of day; a means for inputting BGC-neutral phamacodynamic insulin unit equivalent expenditure data, the data selected from the group consisting of: BGC-neutral d(PDIUE)/dt data, a BGC-neutral rate of pharmacodynamic insulin unit equivalent expenditure; and BGC-neutral ∫ t ⁢ ⁢ 1 t ⁢ ⁢ 2 ⁢ [ ⅆ ( PDIUE ) / ⅆ t ] ⁢ ⅆ t ⁢ ⁢ data , a BGC-neutral amount of pharmacodynamic insulin unit equivalent expenditure between times t 1 and t 2 , where t 1 precedes t 2 ; a microprocessor connected to the input means; the microprocessor connected to a digital memory; the microprocessor connected to wired or wireless communication means; the microprocessor configured to perform calculations based upon inputted recent past blood glucose concentration data; inputted insulin delivery data; inputted insulin time-action profile data; inputted patient R BGC/I data; at least one of: inputted BGC-neutral d(PDIUE)/dt data, a BGC-neutral rate of pharmacodynamic insulin unit equivalent expenditure; and inputted BGC-neutral ∫ t ⁢ ⁢ 1 t ⁢ ⁢ 2 ⁢ [ ⅆ ( PDIUE ) / ⅆ t ] ⁢ ⅆ t ⁢ ⁢ data , a BGC-neutral amount of pharmacodynamics insulin unit equivalent expenditure between times t 1 and t 2 , where t 1 precedes t 2 ; the microprocessor configured to calculate blood glucose concentration; a display connected to the microprocessor; for displaying blood glucose concentration.