Patent ID: 7449581

Claim:
A compound of Formula I wherein: W is S, S(O), S(O) 2 or O; X 1 is O, NR 4 (where R 4 is hydrogen or alkyl), S, or CR 5 R 6 (where R 5 and R 6 are independently hydrogen or alkyl) or C═O; X 2 is O or NR 7 ; Ar 1 is aryl or heteroaryl; R 10 is alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, or R 10 W together form a leaving group or hydroxy; R 3 is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, haloalkyl, heteroalkyl, cyanoalkyl, alkylene—C(O)—R 31 (where R 31 is hydrogen, alkyl, hydroxy, alkoxy, amino, monoalkylamino or dialkylamino), amino, monoalkylamino, dialkylamino or NR 32 —Y 3 —R 33 (where Y 3 is —C(O), —C(O)O—, —C(O)NR 34 , S(O) 2 , or S(O) 2 NR 35 ; R 32 , R 34 and R 35 are independently hydrogen or alkyl; and R 33 is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, heteroalkyl or optionally substituted phenyl) or acyl; R 7 is hydrogen or alkyl.