Patent ID: 7919248

Claim:
A method of identifying an agent which modulates IL-13 expression and/or 15-lipoxygenase activity comprising: (a) contacting an experimental sample comprising cells expressing an IL-9 receptor with the agent in the presence of an IL-9 receptor ligand and measuring IL-13 expression and/or 15-lipoxygenase activity in the experimental cell; and (b) contacting a control sample comprising cells that do not express an IL-9 receptor with the agent in the presence of an IL-9 receptor ligand and measuring IL-13 expression and/or 15-lipoxygenase activity in the control cells; wherein a decrease or increase in IL-13 expression and/or 15-lipoxygenase activity in the experimental cells compared to the control indicates that the agent is capable of modulating IL-13 expression and/or 15-lipoxygenase activity.