Patent ID: 7038026

Claim:
A method for purifying a first double-stranded DNA from a solution containing the first double-stranded DNA and a second double-stranded DNA, comprising (i) passing the solution through a first support comprising a covalently coupled oligonucleotide capable of forming a triple helix with said second double-stranded DNA by hybridization with a specific sequence therein, (ii) recovering the solution that passes through the first support, and (iii) passing the recovered solution through a second support comprising a covalently coupled oligonucleotide capable of forming a triple helix with said first double-stranded DNA by hybridization with a specific sequence therein, wherein the specific sequence present in said first double-stranded DNA comprises the sequence AAGAAAAAAAAGAA (SEQ ID NO:29) and the specific sequence present in said second double-stranded DNA comprises the sequence AGAAAAAAAGGA (SEQ ID NO:27), wherein the oligonucleotide capable of forming a triple helix with said first double-stranded DNA comprises the sequence TTCTTTTTTTTCTT (SEQ ID NO:30) and the oligonucleotide capable of forming a triple helix with said second double-stranded DNA comprises the sequence TCTTTTTTTCCT (SEQ ID NO:28).