Patent ID: 8519144

Claim:
A method for the preparation of compound of formula 1, in which a solution containing a compound of formula 2 is added dropwise to a solution containing a compound of formula 3 in which: Met represents Mg or Zn, Y represents Cl, Br, I or acetoxy, Z represents I, Br, Cl, triflate, sulphonate, phosphate, R 1 , R 2 , R 3 , R 4 , which are the same as one another or different, represent hydrogen, a linear and/or branched C 1 -C 4 alkyl, and/or an aryl, and/or a heteroaryl, or R 1 and R 2 and/or R 3 and R 4 , taken together, form a C 3 -C 8 ring, an aryl and/or a heteroaryl, A represents —COR 5 , where R 5 represents hydrogen, a linear and/or branched C 1 -C 4 alkyl, and/or an aryl, and/or a heteroaryl, or A represents —CR 5 (OR 6 )(OR 7 ) where R 5 has the meaning described above and R 6 and R 7 , which are the same as one another or different, represent a linear and/or branched C 1 -C 4 alkyl, and/or an aryl, and/or a heteroaryl, or R 6 and R 7 , joined together, represent a C 1 -C 8 alkyl or alkenyl, in the presence of catalytic systems based on palladium or nickel.