Patent ID: 7001888

Claim:
A method for treating a cancer selected from the group consisting of lung cancer, breast cancer, colon cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, skin cancer and melanoma and low and intermediate grade non-Hodgkin's Lymphoma in a subject, said method comprising administering to said subject an effective amount of a glucose-anti-neoplastic agent conjugate having the formula: wherein L is selected from the group consisting of a bond, alkenyl, alkylamine, alkylether, amide, carbamate, urea, thiocarbamate, thiourea, and combinations thereof; and Z is an anti-neoplastic agent selected from the group consisting of a radionuclide selected from the group consisting of Yttrium-90, Iodine-125, Iodine-131, and Phosphate-32; an iodoaryl group bearing an Iodine-131; hydroxyurea; 3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 5-hydroxypyridine-2-carboxaldehyde thiosemicarbazone; camptothecin and its analogs; carboplat and its analogs; DOTA: methotrexate and its analogs; mitoxantrone, doxorubicin, idarubicin, balrubicin, eprubicin, imatinib, dacarbazine and procarbazine; and mitomycin; each X is independently selected from the group consisting of O and NH; and R 1 , R 3 and R 4 are each members independently selected from the group consisting of H, (C 1 –C 12 )alkyl and (C 1 –C 12 )acyl.