Patent ID: 8487102

Claim:
A compound of formula I wherein R 1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, benzyl, —C(O)-lower alkyl, —C(O)—CH 2 -lower alkoxy, —C(O)—C 3-6 -cycloalkyl, —(CH 2 ) o —C(O)—NRR′, —(CH 2 ) o S(O) 2 -lower alkyl or —S(O) 2 —NR,R′; o is 0 or 1; R and R′ are each independently hydrogen or lower alkyl, or together with the N atom to which they are attached form a 5 or 6 membered heterocycloalkyl ring; R 2 is hydrogen or lower alkyl; R 3 is halogen, lower alkoxy, lower alkyl substituted by halogen or lower alkoxy substituted by halogen; and when n is 2, each R 3 is the same or different; n is 1 or 2; Ar is phenyl optionally substituted by one or two substituents selected from lower alkyl, halogen, lower alkoxy, lower alkyl substituted by hydroxy or cyano, or is a five or six membered heteroaryl group, selected from thiophenyl or pyridinyl which are optionally substituted by lower alkyl or halogen; or a pharmaceutically active acid-addition salt thereof.