Patent ID: 7115644

Claim:
A Compound of the formula (I): m and n are independently 0, 1 or 2; t is 0–10; L is —CH 2 — optionally substituted by alkyl or alkoxy; R 1 is chosen from amino, alkyl, C 3-7 cycloalkyl, aryl, heteroaryl and heterocyclyl each optionally substituted by one to four R a ; R 2 is chosen from mono-or-di-alkylamino, alkylthio, alkoxy, C 3-7 cycloalkyl, aryl, heteroaryl and heterocyclyl each optionally substituted by one to four R b ; each R a and R b are independently chosen from alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, arylalkyl, aryloxy, alkoxy, alkylthio, acyl, alkoxycarbonyl, acyloxy, acylamino, sulphonylamino, aminosulfonyl, alkylsulfonyl, carboxy, carboxamide, hydroxy, oxo, halogen, trifluoromethyl, nitro, nitrile, amino and guanidino each optionally mono-or-di-substituted by alkyl, acyl or alkoxycarbonyl, wherein any of the above R a or R b are optionally halogenated where possible; each R 3 is chosen from alkyl, alkenyl, alkynyl, cycloalkyl, aryl, arylalkyl, aryloxy, alkoxy, alkylthio, acyl, alkoxycarbonyl, acyloxy, acylamino, sulphonylamino, aminosulfonyl, alkylsulfonyl, carboxy, carboxamide, hydroxy, halogen, trifluoromethyl, nitro, nitrile and amino optionally mono-or-di-substituted by alkyl, acyl or alkoxycarbonyl, wherein any of the above R 3 are optionally halogenated where possible; and R 4 is hydrogen; R 5 is chosen from hydrogen and C 1-3 alkyl; or the pharmaceutically acceptable acids and salts or isomers thereof.