Patent ID: 8440714

Claim:
An acid labile lipophilic molecular conjugate (ALLMC) of the formula 1, 1.1 or formula 2: wherein: R is a hydroxyl bearing cancer chemotherapeutic agent; for formula 1 or 1.1: R 1 is hydrogen, C 1 -C 4 alkyl or C 5 -C 22 alkyl; R 2 is C 5 -C 22 alkyl; Y is selected from O, NR′ or S wherein R′ is hydrogen or C 1 -C 6 alkyl; Z is O or S; Q is O or S; and T is O or S; for formula 2: R 2 is a C 1 -C 22 alkyl; T is O or S; and X is a hydrogen or a leaving group selected from the group consisting of mesylates, sulfonates and halogen (Cl, Br and I); and their isolated enantiomers, diastereoisomers or mixtures thereof; or a pharmaceutically acceptable salt thereof.