Patent ID: 7498327

Claim:
A compound of formula I wherein Q is CO 2 R 5 or CH 2 NR 6 COR 7 ; R 1 is H or C 1 -C 6 alkyl; R 2 is an aryl or heteroaryl group each optionally substituted or an optionally substituted 8- to 13-membered bicyclic or tricyclic ring system having a N atom at the bridgehead and optionally containing 1, 2 or 3 additional heteroatoms selected from N, O or S; R 3 and R 4 are each independently H, halogen, CN, OCO 2 R 8 , CO 2 R 9 , CONR 10 R 11 , CNR 12 NR 13 R 14 , SO m R 15 , NR 16 R 17 , OR 18 , COR 19 or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, cycloheteroalkyl, aryl or heteroaryl group each optionally substituted; R 5 and R 6 are each independently H or C 1 -C 6 alkyl; R 7 is C 1 -C 6 alkyl or m is 0 or an integer of 1 or 2; R 8 , R 9 , R 15 and R 19 are each independently H or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, cycloheteroalkyl, aryl or heteroaryl group each optionally substituted; R 10 , R 11 and R 18 are each independently H or a C 1 -C 6 alkyl, aryl or heteroaryl group each optionally substituted or R 10 and R 11 may be taken together with the atom to which they are attached to form a 5- to 7-membered ring optionally containing another heteroatom selected from O, N or S; and R 12 , R 13 , R 14 , R 16 and R 17 are each independently H or a C 1 -C 4 alkyl, aryl or heteroaryl group each optionally substituted; or R 13 and R 14 or R 16 and R 17 may be taken together with the atom to which they are attached to form a 5- to 7-membered ring optionally containing another heteroatom selected from O, N or S; or a stereoisomer thereof or a pharmaceutically acceptable salt thereof.