Patent ID: 7699775

Claim:
A method of employing an analyte monitoring device to measure an analyte amount or concentration in a subject with an analyte monitoring device having first sensor A and second sensor B, said method comprising: contacting the first and second sensors with a physiological fluid of a user containing analyte, in which each sensor is in contact with the physiological fluid; obtaining analyte-related signals from respective first and second sensors, in which each analyte-related signal is related to the amount or concentration of analyte in the subject; using a microprocessor, obtaining a ratio of signals from the first sensor A relative to the second sensor B for one of interpolation and/or extrapolation calculation of estimated signal values; providing a series of analyte-related signals obtained by the analyte monitoring device over time, and replacing an unusable analyte-related signal with an estimated signal by either: (A) if one or more analyte-related signals previous to the unusable analyte-related signal and one or more analyte-related signals subsequent to the unusable analyte related signal are available, then interpolation is used to estimate the unusable, intervening analyte-related signal; or (B) if two or more analyte-related signals previous to the unusable analyte-related signal are available, then extrapolation is used to estimate the unusable, subsequent analyte-related signal.