Patent ID: 6927219

Claim:
A compound of the formula: wherein A is —(C═O)NH— or —NH(C═O)—; X, Y and Z are ═(CR 3 )—, ═(CR 4 )—, and ═(CR 5 )—; or ═N—, ═(CR 4 )—, and ═(CR 5 )—; or ═(CR 3 )—, ═N—, and ═(CR 5 )—; or ═(CR 3 )—, ═(CR 4 )—, and ═N—; or ═N—, ═(CR 4 )—, and ═N—; or ═(CR 3 )—, ═N—, and ═N—; or ═N—, ═N—, and CR 5 , respectively; W is a bond; m is an integer from 1 to 2; R 1 is R 2 is selected from the group consisting of (i) hydrogen, (ii) halogen, (iii) cyano, (iv) (C 1 -C 4 )alkyl optionally substituted by one to four chloro or fluoro, (v) (C 2 -C 4 )alkenyl; (vi) (C 2 -C 4 )alkynyl and (vii) (C 1 -C 4 )alkyloxy optionally substituted by one to four chloro or fluoro; R 3 , R 4 and R 5 are each independently selected from the group consisting of (i) hydrogen; (ii) halogen, (iii) cyano, (iv) nitro, (v) amino, (vi) hydroxyl, (vii) (C 1 -C 6 )alkyl optionally substituted by one to four chloro or fluoro, (viii) (C 3 -C 8 )cycloalkyl optionally substituted by one to four chloro or fluoro, (ix) (C 1 -C 6 )alkyloxy optionally substituted by one to four chloro or fluoro, and (x) (C 3 -C 8 )cycloalkyloxy optionally substituted by one to four chloro or fluoro; R 8 is absent or is selected from the group consisting of hydrogen, —CF 3 , (C 1 -C 6 )alkyl, HO—(C 2 -C 6 )alkyl and (C 3 -C 8 )cycloalkyl; R 9 is selected from the group consistion of hydrogen, halo, (C 1 -C 6 )alkyl optionally substituted with one to six fluoro, —CO 2 H, HO—(C 2 -C 6 )alkyl, (C 1 -C 6 )alkoxy optionally substituted with one to six fluoro, hydroxy, (C 1 -C 10 )heteroaryl and (C 3 -C 8 )cycloalkyl, each R 10 is independently selected from the group consisting of hydrogen and halo; or a pharmaceutically acceptable salt or solvate thereof.