Patent ID: 8846711

Claim:
A compound which is a compound of formula (I): wherein: W and X independently represent a bond or a —(CH 2 ) 1-4 group, such that W and X together contain 1-5 carbon atoms; R1 represents an H, F, CN, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, CO 2 R d , COR d , CONR a R b , OCOR d , OR d , NR a R b , ON═CR d R e , NR c COR d , NR c COOR d , OCONR a R b , NR c CONR a R b , NR c SO 2 R a , S(O) n R a , SO 2 NR a R b , —C(R a )═N—O—R f , Y—Ar or a Z-Het group, wherein Ar represents phenyl or naphthyl, Het represents a 4-10 membered monocyclic or bicyclic saturated or unsaturated heterocycle containing 1-5 heteroatoms selected from N, O and S and Y and Z independently represent a bond or a linker selected from O, S, CO, (C 1 -C 6 ) alkylene, —O—(C 1 -C 6 ) alkylene, —CO—(C 1 -C 6 ) alkylene or —ON═CR d —(C 1 -C 6 ) alkylene, wherein said R1 group may be optionally substituted by one or more R4 groups; R2 represents an H, F, CN, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, CO 2 R d , COR d , CONR a R b , OCOR d , OR d , NR a R b , ON═CR d R e , NR c COR d , NR c COOR d , OCONR a R b , NR c CONR a R b , NR c SO 2 R a , S(O) n R a or SO 2 NR a R b group; R a , R b and R c independently represent H, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, or an NR a R b group may optionally form a 3- to 7-membered nitrogen containing saturated heterocycle optionally containing 1 to 3 additional heteroatoms selected from N, O or S wherein said heterocycle may be optionally substituted by one or more (C 1 -C 6 ) alkyl groups; R d and R e independently represent H, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, halo(C 1 -C 6 ) alkyl, halo(C 1 -C 6 ) alkyl-O—(C 1 -C 6 ) alkyl- or (C 1 -C 6 ) alkyl-O—(C 1 -C 6 ) alkyl-; R f represents (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, halo(C 1 -C 6 ) alkyl or —(C 1 -C 6 ) alkyl-Ar, wherein Ar represents phenyl or naphthyl; —R4 represents halogen, CN, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, CO 2 R d , COR d , CONR a R b , OCOR d , OR d , NR a R b , ON═CR d R e , NR c COR d , NR c COOR d , OCONR a R b , NR c CONR a R b , NR c SO 2 R a , S(O) n R a , or SO 2 NR a R b ; n represents an integer selected from 0 to 2; R3 represents a heterocycle of formula (a): wherein said R3 group may be optionally substituted by one or more R5 groups; R5 is selected from the group consisting of F, CO 2 R d , COR d , CONR a R b , OR d , ═O, NR a R b , NR a COR d or (C 1 -C 6 ) alkyl optionally substituted by F, CO 2 R d , CONR a R b , OR d , NR a R b , NR a COR d or Het optionally substituted by one or more (C 1 -C 6 ) alkyl groups; or a pharmaceutically acceptable salt or solvate thereof.