Patent ID: 8754086

Claim:
A compound of formula I, wherein: X and Y independently represent —O— or —N(R a )—; R a represents H or C 1-6 alkyl optionally substituted by one or more fluoro atoms; R 1 and R 2 independently represent H, C 1-6 alkyl optionally substituted by one or more fluoro atoms, —C(O)C 1-6 alkyl optionally substituted by one or more fluoro atoms, or —CH 2 -phenyl wherein the phenyl moiety is optionally substituted by one or more substituents selected from halo and C 1-3 alkyl or, R 1 and R 2 may together represent a C 1-2 alkylene linker group; R 3 , R 4 , R 5 , R 5a , R 6 , R 7 , R 8 , R 9 , and R 10 independently represent H, halo, —OR b , —N(R c )R d , C 1-6 alkyl optionally substituted by one or more fluoro atoms, or —CH 2 -phenyl wherein the phenyl moiety is optionally substituted by one or more substituents selected from halo and C 1-3 alkyl; or any two adjacent R 6 , R 7 , R 8 , and R 9 groups may be linked together to form a further 3- to 8- membered ring optionally containing one to three double bonds, optionally containing one to four heteroatoms, and wherein the ring is itself optionally substituted by one or more substituents selected from halo and C 1-4 alkyl optionally substituted by one or more fluoro atoms; R b represents H, C 1-6 alkyl optionally substituted by one or more fluoro atoms, or —C(O)C 1-6 alkyl optionally substituted by one or more fluoro atoms; R c and R d independently represent H or C 1-6 alkyl optionally substituted by one or more fluoro atoms; R 11 and R 12 independently represent H, C 1-6 alkyl optionally substituted by one or more fluoro atoms, —C(O)C 1-6 alkyl optionally substituted by one or more fluoro atoms, phenyl optionally substituted by one or more substituents selected from halo and C 1-3 alkyl, or —CH 2 -phenyl wherein the phenyl moiety is optionally substituted by one or more substituents selected from halo and C 1-3 alkyl; R 13 and R 14 independently represent H, C 1-6 alkyl optionally substituted by one or more fluoro atoms, or —CH 2 -phenyl wherein the phenyl moiety is optionally substituted by one or more substituents selected from halo and C 1-3 alkyl, or a pharmaceutically-acceptable salt, ester, stereoisomer or tautomer thereof.