Patent ID: 7238709

Claim:
A compound of the formula: wherein: A is phenyl; B″ is —O—; R X is alkyl, alkenyl, or alkynyl, each optionally substituted with 1 to 5 alkoxy or fluoro substituents; R 1 is hydrogen or alkyl; R 2 is phenyl; K is a bond; K″ is a bond; and B is a piperidine ring; R 46 is alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, or heterocycle; R 47 is alkyl, substituted alkyl, aryl, acyl, heterocycle, or —COOR 50 where R 50 is alkyl; or R 46 and R 47 together with the nitrogen atom to which they are attached form a heterocycle, which hetorocycle is optionally substituted with one or more alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aminoacyloxy, oxyaminoacyl, azido, cyano, halo, hydroxyl, keto, thioketo, carboxyl, carboxyalkyl, thioaryloxy, thioheteroaryloxy, thioheterocyclooxy, thiol, thioalkoxy, substituted thioalkoxy, aryl, aryloxy, heteroaryl, heteroaryloxy, heterocycle, heterocyclooxy, hydroxyamino, alkoxyamino, nitro, —SO-alkyl, —SO-substituted alkyl, —SO-aryl, —SO-heteroaryl, —SO 2 -alkyl, -SO 2 -substituted alkyl, —SO 2 -aryl or —SO 2 -heteroaryl; X is alkylene optionally substituted with one, two, or three hydroxy groups, alkylene wherein one, two, or three carbon atoms have been replaced by an oxygen atom, or an -alkylene-phenylene-alkylene- wherein the phenylene ring is optionally substituted with one or two chloro or fluoro groups; or a pharmaceutically acceptable salt thereof.