Patent ID: 8101183

Claim:
A monoclonal antibody or antibody fragment that competes for specifically binding to a polypeptide consisting of the amino acid sequence of SEQ ID NO: 2 wherein the monoclonal antibody is selected from the group consisting of: a) a monoclonal antibody comprising i) a heavy chain variable domain comprising a first CDR sequence consisting of amino acid sequence SEQ ID NO: 51, a second CDR sequence consisting of SEQ ID NO: 52 or SEQ ID NO: 57, and a third CDR sequence consisting of SEQ ID NO:53; and ii) a light chain variable domain comprising a CDR sequence consisting of amino acid sequence SEQ ID NO: 54, a second CDR sequence consisting of SEQ ID NO: 55, and a third CDR sequence consisting of SEQ ID NO:56; and b) a monoclonal antibody comprising i) a heavy chain variable domain comprising a first CDR sequence consisting of amino acid sequence SEQ ID NO: 63, a second CDR sequence consisting of SEQ ID NO: 64, and a third CDR sequence consisting of SEQ ID NO:65; and ii) a light chain variable domain comprising a CDR sequence consisting of amino acid sequence SEQ ID NO: 66, a second CDR sequence consisting of SEQ ID NO: 67, and a third CDR sequence consisting of SEQ ID NO:68.