Patent ID: 8779151

Claim:
A compound selected from the group consisting of: wherein R 1 is —H or cyano and R 2 is heteroatom-unsubstituted C 3 -C 7 -cycloalkyl; wherein X 1 is halo and R 3 is heteroatom-unsubstituted C 3 -C 7 -cycloalkyl, C 6 -C 10 -aryl, or C 7 -C 10 -aralkyl; wherein X 2 is halo and R 4 is hydroxy or heteroatom-unsubstituted C 1 -C 10 -acyloxy; wherein: X 3 is halo or heteroatom-unsubstituted C 1 -C 10 -alkyl or C 1 -C 10 -alkoxy, R 5 is —H or cyano, and R 6 is heteroatom-unsubstituted C 3 -C 7 -cycloalkyl, C 1 -C 10 -acyloxy, C 6 -C 10 -aryl, or C 7 -C 10 -aralkyl; wherein: X 4 is halo or heteroatom-unsubstituted C 1 -C 10 -alkyl or C 1 -C 10 -alkoxy, R 7 is —H or cyano, and R 8 is a heteroatom-unsubstituted C 3 -C 7 -cycloalkyl, C 1 -C 10 -acyloxy, C 6 -C 10 -aryl, or C 7 -C 10 -aralkyl; wherein: X 5 is heteroatom-unsubstituted C 1 -C 10 -alkyl or C 1 -C 10 -alkoxy, R 9 is —H or cyano, and R 10 is a heteroatom-unsubstituted C 3 -C 7 -cycloalkyl, C 1 -C 10 -acyloxy, C 6 -C 10 -aryl, or C 7 -C 10 -aralkyl; and wherein: A is —C(O)—, and X 6 is halo or heteroatom-unsubstituted C 1 -C 10 -alkyl or C 1 -C 10 -alkoxy, R 11 is heteroatom-unsubstituted C 3 -C 7 -cycloalkyl, C 1 -C 10 -acyloxy, C 6 -C 10 -aryl, or C 7 -C 10 -aralkyl; or a pharmaceutically acceptable salt or tautomer thereof.