Patent ID: 7265115

Claim:
A compound of formula I or a pharmaceutically acceptable salt thereof wherein: V is selected from the group consisting of a covalent bond and CH 2 ; W is selected from the group consisting of a covalent bond and CH 2 ; X is selected from the group consisting of a covalent bond and CH 2 ; Y is selected from the group consisting of a covalent bond and CH 2 ; Z is CH 2 ; L 1 is selected from the group consisting of a covalent bond and (CH 2 ) n ; n is 1-5; R 1 is selected from the group consisting of R 2 is selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl, aminoalkyl, aminocarbonylalkyl, benzyloxycarbonyl, cyanoalkyl, dihydro-3-pyridinylcarbonyl, hydroxy, hydroxyalkyl, phenoxycarbonyl, and —NH 2 ; R 4 is selected from the group consisting of hydrogen, alkyl, and halogen; R 5 is selected from the group consisting of hydrogen, alkoxy, alkyl, halogen, nitro, and —NH 2 ; R 6 is selected from the group consisting of hydrogen, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, alkyl, alkylcarbonyl, alkylcarbonyloxy, alkylthio, alkynyl, amino, aminoalkyl, aminocarbonyl, aminocarbonylalkyl, aminosulfonyl, carboxy, carboxyalkyl, cyano, cyanoalkyl, formyl, formylalkyl, haloalkoxy, haloalkyl, halogen, hydroxy, hydroxyalkyl, mercapto, mercaptoalkyl, nitro, 5-tetrazolyl, —NR 7 SO 2 R 8 , —C(NR 7 )NR 7 R 8 , —CH 2 C(NR 7 )NR 7 R 8 , —C(NOR 7 )R 8 , —C(NCN)R 7 , —C(NNR 7 R 8 )R 8 , —S(O) 2 OR 7 , and —S(O) 2 R 7 ; and R 7 and R 8 are independently selected from the group consisting of hydrogen and alkyl; with the proviso that when V is a covalent bond, then X is a covalent bond, W is CH 2 and Y is CH 2 , or when V is CH 2 , then X is CH 2 W is a covalent bond, and Y is a covalent bond.