Patent ID: 8071567

Claim:
A method of treating a disease mediated by the HCV virus comprising administering to a patient in need thereof an effective amount of a compound of formula I wherein R is hydrogen or â€”[P(O)(OH)â€”O] n H and n is 1, 2 or 3; R 1 is alkyl, alkenyl, alkynyl, haloalkyl, alkylcarbonyl, hydroxyalkyl, alkoxyalkyl, alkoxy, cyano, azido, hydroxyiminomethyl, alkoxyiminomethyl, halogen, alkylcarbonylamino, alkylaminocarbonyl, or aminomethyl, alkylaminomethyl, dialkylaminomethyl or heterocyclyl; R 2 is hydrogen, hydroxy, alkyl, alkoxy, halogen or cyano; R 3 and R 4 (i) independently are hydrogen, hydroxy, alkoxy or halogen, provided that at least one of R 3 and R 4 is hydrogen; or (ii) together represent â•CH 2 or â•Nâ€”OH, or (iii) both represent fluorine; R 11 is hydrogen, halogen or alkyl X is O, S or CH 2 ; or pharmaceutically acceptable salts thereof.