Patent ID: 8278349

Claim:
A pharmaceutical composition useful in the treatment of pancreatic cancer or a glioblastoma, comprising effective amounts of a Ras antagonist represented by the formula: wherein R 1 represents farnesyl or geranylgeranyl; R 2 is COOR 7 , or CONR 7 R 8 , wherein R 7 and R 8 are each independently hydrogen, alkyl or alkenyl; R 3 , R 4 , R 5 and R 6 are each independently hydrogen, alkyl, alkenyl, alkoxy, halo, trifluoromethyl, trifluoromethoxy, or alkylmercapto; and X represents S; or a pharmaceutically acceptable salt thereof; and 2-deoxyglucose (2DG); and a pharmaceutically acceptable carrier.