Patent ID: 8309544

Claim:
A compound of formula Ia or a pharmaceutically acceptable salt thereof: wherein A is selected from imidazole-2-yl, pyrrol-2-yl, and pyrid-2-yl; the group is selected from 4-biphenyl, 3-quinolinyl, 6-(methoxycarbonyl)-2-naphthyl, 7-trifluoromethyl-3-quinolinyl, 2-naphthyl, 4-bromophenyl, 6,7-bis(cyano)-2-naphthyl, (3-methyl-4-phenyl)-phenyl, 4-(4-methoxyphenyl)phenyl, N-methyl-1,4-benzoxazin-7-yl, 4-(4-fluorophenyl)phenyl, 4-(1-pyrrolyl)phenyl, 4-(4-t-butylphenyl)phenyl, 2-(trifluoromethyl)-6-quinolinyl, 3-(trifluoromethyl)-7-isoquinolinyl, 3-(trifluoromethyl)-7-quinolinyl, 2-(trifluoromethyl)-6-quinoxalinyl, 2-(trifluoromethyl)-6-quinazolinyl, 2-oxo-6-benzoxazolinyl, 5-indolyl, pyrazolo[3,4-b]pyrid-5-yl, 3-chloro-7-cinnolinyl, 4-(3-pyridyl)phenyl, 4-(3-cyanophenyl)phenyl, 3-(phenyl)phenyl, 2-(cyclopropyl)-5-pyridyl, 6-chromonyl, 3,4-dimethylphenyl, 6-quinolinyl, 6-isoquinolinyl, 4-(phenoxy)phenyl, 7-(methoxy)-3-quinolinyl, 7-chloro-3-quinolinyl, 2-(1-pyrrolyl)-5-pyridyl, 2-methoxy-5-pyridyl, 2-hydroxy-5-pyridyl, 2-(dimethylamino)-5-pyridyl, and 1-naphthyl; R 3 , R 4 and R 5 are independently selected from hydrogen, F, OH, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, and —OC 1 -C 4 alkyl; R 6 , R 7 and R 8 are independently selected from hydrogen, halo, CN, and C 1 -C 6 alkyl optionally substituted with one to five fluorine atoms; and R 9 , R 10 and R 11 are independently selected from hydrogen, halo, NH 2 , N(C 1 -C 6 alkyl) 2 , NO 2 , CN, N 3 , —OH, C 3 -C 10 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, —O-aryl, aryl-S(O) 0-2 , (C 0 -C 6 alkyl)S(O) 0-2 (C 0 -C 6 alkylene)-, (C 0 -C 6 alkyl)C(O)NH—, H 2 N—C(NH)—, (C 0 -C 6 alkyl)C(O)—, (C 0 -C 6 alkyl)OC(O)(C 0 -C 6 alkylene)-, C 0 -C 6 alkyl)O(C 1 -C 6 alkylene)-, (C 0 -C 6 alkyl)C(O) 1-2 (C 0 -C 6 alkylene)-, (C 0 -C 6 alkyl) 2 NC(O)—, (C 0 -C 6 alkyl)OC(O)NH—, aryl, aralkyl, heteroaryl, heteroaralkyl, C 1 -C 6 alkyl optionally substituted with one to five fluorine atoms, and —O(C 1 -C 6 alkyl) optionally substituted with one to five fluorine atoms.