Patent ID: 7939278

Claim:
A method of determining a phenotype of an individual from whom a first cell population has been obtained, said method comprising: determining signaling node states of a plurality of signaling nodes in one or more cells of a first cell population; comparing said signaling node states of said plurality of signaling nodes in said first cell population with signaling node states of said plurality of signaling nodes in at least a second cell population or data representing said signaling node states of said plurality of signaling nodes in said second cell population, wherein said compared signaling node states are states that have been determined under culture conditions comprising: (i) a presence of a same potentiator or a fragment thereof, or (ii) a presence of no potentiator, wherein said compared signaling node states are determined by a method comprising: contacting each of said cell populations with at least one distinguishably detectable state-specific binding element for each of said signaling node states of said plurality of signaling nodes; and detecting a level of binding of each of said distinguishably detectable state-specific binding element for each of said signaling node states of each of said plurality of signaling nodes in each of said cell populations; and determining a phenotype of said individual based on said comparison.