Patent ID: 8895583

Claim:
A compound of structural Formula I: and pharmaceutically acceptable salts thereof, wherein: X is selected from the group consisting of CH, and CR 2 ; R 1a and R 1b are independently selected from the group consisting of —H, —F, —Cl, —Br, —CN, cyclopropyl, —C 1-3 alkyl optionally substituted with one to six of —F, and —O—C 1-3 alkyl optionally substituted with one to six of —F; R 2 is selected from the group consisting of —F, —Cl, —Br, —CN, cyclopropyl, —C 1-3 alkyl optionally substituted with one to six of —F, and —O—C 1-3 alkyl optionally substituted with one to six of —F; R 3a and R 3b are independently selected from the group consisting of —H, —F, —Cl, —Br, —CN, —C 1-3 alkyl optionally substituted with one to six of —F, and —O—C 1-3 alkyl optionally substituted with one to six of —F; A is wherein R 13 is selected from the group consisting of —H and —C 1-6 alkyl; R 4 is a heterocycle selected from the group consisting of: R 5 is selected from the group consisting of —H, —F, —OH, —CF 3 , —OC 1-3 alkyl and —OCF 3 ; j is an integer 1; k is an integer 1; R 7 is selected from the group consisting of (a) —H, (b) —C 1-6 alkyl optionally substituted with one to six of —F, (c) —C 1-3 alkyl substituted with one or two of —OCH 3, (d) —(CH 2 ) 0-1 —C 3-6 cycloalkyl optionally substituted with (i) one to three of —F or (ii) C 1-3 alkyl optionally substituted with one to three of —F, R 8 is selected from the group consisting of —H, —F, —OH, and —C 1-3 alkyl optionally substituted with one to six of —F; R 9 is selected from the group consisting of (a) —H, (b) —F, (c) —OH, (d) —C 1-3 alkyl optionally substituted with substituents selected from the group consisting of (i) —OH and (ii) one to six of —F, (e) —C 3-b cycloalkyl optionally substituted with one to three of —F, and (f) —O—C 1-3 alkyl optionally substituted with —OH; R 10 is selected from the group consisting of (a) —H, (b) —F, (c) —C 1-3 alkyl optionally substituted with with substituents selected from (i) —OH and (ii) one to six of —F, and (d) —O—C 1-3 alkyl; R 11 is selected from the group consisting of (a) —H, (b) —C 1-6 alkyl optionally substituted with one to six of —F, (c) —C 3-6 cycloalkyl optionally substituted with —CH 3 , —CF 3 , —CN, —OH, or —NH 2 or one to three of —F; R 12a is selected from the group consisting of (a) —H, (b) —C 1-6 alkyl optionally substituted with one to six of —F, (c) —C 3-6 cycloalkyl optionally substituted with —CH 3, —CF 3 , —CN, —OH, or one to three of —F; and R 12 is selected from the group consisting of (a) —C 1-6 alkyl optionally substituted with one to six of —F, and (b) —C 3-6 cycloalkyl optionally substituted with one to three of —F.