Patent ID: 8591734

Claim:
A vapor liquid separator for use in a method of separating a substance by supercritical fluid chromatography of injecting a sample comprising a desired substance into a mobile phase comprising a supercritical fluid and a solvent, passing the sample through a column for separating the desired substance from the sample to separate the desired substance in the sample, dividing the mobile phase that has been passed through the column into the solvent and a gas, and separating the desired substance from the solvent, wherein the vapor liquid separator comprises: an external cylinder having ends both of which being opened; a flange portion for clogging an opening at one end of the external cylinder; an introduction portion for introducing the mobile phase into the external cylinder in a circumferential direction along an inner peripheral wall surface of the external cylinder; and an internal cylinder having ends both of which being opened and which penetrates through the flange portion to extend closer to an other end side of the external cylinder than the introduction portion.