Patent ID: 8680026

Claim:
A device for detecting a target molecule, comprising: a reaction chamber comprising an inlet; an outlet; a target capturing surface that binds specifically to the target molecule, a bottom surface of the reaction chamber, wherein the bottom surface comprises the target capturing surface, wherein the target capturing surface comprises a microarray; and a top surface of the reaction chamber, wherein the top surface is a hydrophilic surface; side walls of the reaction chamber, wherein the side walls are hydrophobic, a waste chamber having an absorbent to allow liquids to be advanced by capillary action through the reaction chamber for washing; and a channel of variable width connecting the reaction chamber to the waste chamber, wherein the channel comprises two sections, a first section at the end proximate to the reaction chamber and a second section at the end proximate to the waste chamber, wherein the first section has a diameter or cross-section area that is larger than the diameter or cross-section area of the second section, wherein the second section further comprises two subsections: a first subsection next to the first section and a second subsection next to the waste chamber, wherein the first subsection forms an angle with the second subsection and has a diameter that is larger than the diameter of the second subsection.