Patent ID: 7879984

Claim:
A human antibody or antigen-binding fragment of an antibody that specifically binds human CD20 and is capable of inducing complement dependent cytotoxicity (CDC), wherein the antibody or antibody fragment comprises: (i) a heavy chain complementarity determining region 1 (HCDR1) having the amino acid sequence of SEQ ID NO:341; (ii) a heavy chain complementarity determining region 2 (HCDR2) having the amino acid sequence of SEQ ID NO:343; (iii) a heavy chain complementarity determining region 3 (HCDR3) having the amino acid sequence of SEQ ID NO:345; (iv) a light chain complementarity determining region 1 (LCDR1) having the amino acid sequence of SEQ ID NO:349; (v) a light chain complementarity determining region 2 (LCDR2) having the amino acid sequence of SEQ ID NO:351; and (vi) a light chain complementarity determining region 3 (LCDR3) having the amino acid sequence of SEQ ID NO:353.