Patent ID: 8666472

Claim:
A method of arterial endothelial function measurement, the method comprising: a) imparting a first set of one or more artificial pulses into an artery endothelium using an actuator, said artery endothelium having an initial pulse transit speed; b) detecting the arrival of at least one of the one or more artificial pulses at a detector to determine the initial pulse transit speed; c) modifying the artificial pulse transit speed of said artery endothelium; d) imparting a second set of one or more artificial pulses using an actuator into said artery endothelium; e) detecting the arrival of at least one of the one or more artificial pulses with said detector to form a modified pulse transit speed; f) calculating a difference between said modified pulse transit speed and said initial pulse transit speed; and g) calculating a ratio between said modified pulse transit speed and said initial pulse transit speed, wherein said ratio is a measurement of arterial endothelial function.