Patent ID: 7091359

Claim:
A process for preparing a benzyl thiazolidinedione compound, wherein said benzyl thiazolidinedione compound is selected from the group consisting of 5-{4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl}-2,4-thiazolidinedione, a tautomeric form thereof, a pharmaceutical acceptable salt thereof, and a pharmaceutically acceptable solvate thereof, said process comprising catalytically reducing a benzylidine thiazolidinedione compound, wherein said reduction is conducted using: a) a hydrogen pressure above 20psi, and b) a reaction solvent selected from the group consisting of acetic acid, aqueous acetic acid, an alkanol, an alkanol mixed with an aqueous mineral acid, tetrahydrofuran, and tetrahydrofuran admixed with an aqueous mineral acid, wherein said benzylidine thiazolinedione compound is selected from the group consisting of 5-{4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzylidene}-2,4 -thiazolidinedione, a tautomeric form thereof, a salt thereof, and a solvate thereof.