Patent ID: 7160555

Claim:
An immediate release oral pharmaceutical composition comprising, as an active ingredient a calcium salt of a benzylsuccinic acid represented by the formula: or its hydrate, wherein the calcium salt of benzylsuccinic acid or its hydrate and at least one member selected from the group consisting of silicon dioxide and partly pregelatinized starch as a disintegrating and dissolution aid, as said immediate release oral pharmaceutical composition exhibit a dissolution rate in human gastric juice when said silicon dioxide is present in an amount of 0.5 to 5% by weight based on the total weight of the composition or said partly pregelatinized starch present in an amount of from 5 to 20% by weight based on the total weight of said immediate release oral composition, wherein the dissolution rate is determined using 900 ml of first fluid of the Japanese Pharmacopoeia at 50 rpm according to the paddle method, apparatus 2, of the dissolution test methods of the 13 th revised Japanese Pharmacopoeia, said dissolution rate being such that 75% or more of said active ingredient releases within 20 minutes of administering said immediate release oral composition.