Patent ID: 7666905

Claim:
A method for treating a cancer in a mammal comprising administering to the mammal an effective amount of at least one hepoxilin analog of the formula: wherein X is S, NH or CH 2 R 1 is lower alkenyl; —CH 2 CH═CH—(CH 2 ) 3 —COR″ wherein R″ is OH, O— lower alkyl or alkenyl; or Y—R 4 wherein Y is —CH 2 —CH═CH—(CH 2 ) 3 , lower alkyl or alkenyl and R 4 is CONH-Z or COO-Z wherein Z is a sugar moiety; R 2 is OH, NH 2 , SH, OPO 3 H, lower alkyl or alkenyl or O— lower alkyl or alkenyl; and R 3 is lower alkenyl or —CH 2 —CH═CH—(CH 2 ) 4 —R′″ wherein R″ is CH 3 , CH 2 OH, CH 2 —O— lower alkyl or alkenyl, phenyl or substituted phenyl or wherein X, R 2 and R 3 are as defined for formula I and R 5 is lower alkenyl; —CH═CH—CH 2 —CH═CH—(CH 2 ) 3 —COR″ wherein R″═OH or O— lower alkyl or alkenyl; or Y—R 6 wherein Y is —CH═CH—CH 2 —CH═CH—(CH 2 ) 3 , lower alkyl or alkenyl and R 6 is CONH-Z or COO-Z wherein Z is a sugar moiety, wherein the cancer is selected from the group consisting of leukemia and cancer of the prostate or breast.