Patent ID: 8202535

Claim:
A method of treating pain in a subject, comprising administering a small volume substantially homogeneous solid tablet by adhering said tablet to the oral mucosa of said subject, wherein: a) said tablet has a volume of from about 3 microliters (mcl) to about 15 mcl; b) said tablet comprises from about 2 to about 200 micrograms (mcg) of sufentanil and a bioadhesive material; c) said bioadhesive material provides for adherence of said tablet to the oral mucosa substantially throughout during the period of drug delivery; d) said tablet generates a minimal saliva response and minimal swallowing of drug; e) at least 50% of drug delivery occurs via the oral transmucosal route; and f) administration of said tablet to said subject results in a T max of from about 19.8 minutes to about 60 minutes.