Patent ID: 7951533

Claim:
A method for determining the structure of a functional substance, which is a substance having an affinity to a target, comprising: synthesizing functional substance candidates having a specific substituent group which bonds covalently thereto, and hinders a reaction selected from the group consisting of PCR, LCR, Self-Sustained Sequence Replication, SDA, RT-PCR, ICAN, and LAMP; selecting and separating a functional substance having a specific substituent group which bonds covalently thereto, hinders said reaction, and has an affinity to the target from among said functional substance candidates having the specific substituent group; eliminating the specific substituent group from said selected functional substance having the specific substituent group, to produce a substance without the specific substituent group; amplifying said substance without the specific substituent group by said reaction, to produce an amplified substance; and determining the structure of said amplified substance as the structure of said selected functional substance, wherein said functional substance is a nucleotide sequence; and said specific substituent group comprises at least one group selected from the groups represented by formulae (1) to (10)