Patent ID: 7119099

Claim:
A compound of formula (I), or an enantiomer or diastereoisomer thereof: wherein: A is a 5- or 6-membered carbocyclic ring; X is H and W is OH; or X and W together form a carbonyl group or an epoxide; R 1 is H; or one or two substituents independenly selected from the group consisting of: hydroxy; halo; lower alkyl; lower alkoxy; lower thioalkyl; haloalkyl (e.g. trifluoromethyl) or —C(O)R 2 wherein R 2 is lower alkyl, aryloxy or benzyloxy; Y is phenyl optionally mono- or di-substituted with R 5 or C(O)R 6 , wherein R 5 is lower alkyl, lower cycloalkyl, lower alkoxy, halo, hydroxy, nitrile or trifluoromethyl, and R 6 is lower alkyl, lower cycloalkyl, lower alkoxy, hydroxy or trifluoromethyl said phenyl ring being optionally fused with a saturated or unsaturated 4 to 6-membered carbocyclic ring; R 3 is selected from the group consisting of: aryl, mono- or di-substituted with: Het, said Het optionally mono- or di-substituted with lower alkyl, lower cycloalkyl, lower alkoxy, halo, hydroxy, nitrile, trifluoromethyl, C(O)R 6 wherein R 8 is as defined above; wherein each Het is independently a five membered, unsaturated heterocycle containing from one to three heteroatoms selected from nitrogen, oxygen and sulfur; and R 4 is a carboxylic acid, a salt or an ester thereof.