Patent ID: 7375106

Claim:
A method for the treatment of pain in a patient in need thereof, comprising: administering to the patient an effective amount of a non-steroidal anti-inflammatory drug (NSAID) and a diarylmethyl piperazine oploid analgesic according to formula (I): wherein: R 8 is phenyl substituted with one or more constituents selected from halogen and trifluoromethyl, and R 9 is hydrogen, saturated C 1 -C 6 hydrocarbyl or unsaturated C 3 -C 6 hydrocarbyl; R 3 and R 5 are each independently hydrogen or methyl, at least one of them being methyl; R 4 is hydrogen or methyl, except that when R 3 and R 5 are both methyl R 4 is hydrogen; and R 6 is hydrogen, saturated C 1 -C 6 hydrocarbyl, unsaturated C 3 -C 6 hydrocarbyl or C 2 -C 6 methoxyalkyl; or a pharmaceutically acceptable ether, ester or salt thereof or a physiologically functional derivative thereof.