Patent ID: 8283383

Claim:
A compound of formula I wherein: R 1 is: phenyl substituted at the 4-position with methyl or halo and which may be substituted at the 2-position with halo; R 2 is: hydrogen; or C 1-6 alkyl; R 3 is: C 1-6 alkyl; hydroxy-C 1-6 alkyl; C 1-6 alkoxy-C 1-6 alkyl; halo-C 1-6 alkyl; C 3-7 cycloalkyl; heteroaryl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; heterocyclyl; heterocyclyl-C 1-6 alkyl; or C 3-7 cycloalkyl-C 1-6 alkyl; or R 2 and R 3 together form a C 3-7 cycloalkyl; R 4 is: hydrogen; C 1-6 alkyl; C 3-7 cycloalkyl; C 3-7 cycloalkyl-C 1-6 alkyl; or pyrimidinyl; R 5 is: C 1-6 alkyl; C 1-6 alkoxy; C 3-7 cycloalkyl; C 1-6 alkoxy-C 1-6 alkyl; amino-C 1-6 alkyl; oxetanyl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; phenyl which may be unsubstituted or substituted once or twice with a group or groups independently selected from C 1-6 alkyl, halo, halo-C 1-6 alkyl and C 1-6 alkoxy; thienyl which may be unsubstituted or substituted once or twice with a group or groups independently selected from C 1-6 alkyl and C 1-6 alkoxy; furanyl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; thiazolyl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; oxazolyl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; isoxazolyl which may be unsubstituted or substituted once or twice with a group or groups independently selected from C 1-6 alkyl and phenyl; pyrazolyl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; thiadiazolyl which may be unsubstituted or substituted once with C 1-6 alkyl; tetrahydropyranyl; morpholinyl; piperidinyl which may be unsubstituted or substituted with C 1-6 alkyl or acetyl; pyrimidinyl; or pyridinyl which may be unsubstituted or substituted once or twice with C 1-6 alkyl; and R 6 , R 7 and R 8 each independently is: hydrogen; or halo.