Patent ID: 7285554

Claim:
A pyrazole compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof wherein each symbol has the following meaning, D: 1H-pyrazol-1-yl, 1H-pyrazol-3-yl or 1H-pyrazol-5-yl, each of which may have 1 to 2 substituents selected from the group consisting of -lower alkyl(“Alk”), -lower alkenyl, lower alkynyl, halogeno-lower alkyl-, -cycloalkyl, —O-Alk, —COO-Alk and -halogen atom(“Hal”), n: 0, B: 1,4-phenylene or thiophene-2,5-diyl, X: —NH—CO — or —CO—NH—, and A: aryl which may have one or more substituents of group F; mono- or di-cyclic fused heteroaryl selected from the group consisting of thienyl, furanyl, pyrrolyl, imidazolyl, pyrazolyl, thiazolyl, isothiazolyl, oxazolyl, isoxazolyl, tetrazolyl, triazolyl, thiadiazolyl, pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl, indolyl, isoindolyl, isoquinolyl, quinolyl, quinoxanyl, phthalazinyl, imidazo [1,2-a]pyridyl, quinazolinyl and cinnolinyl which may have one or more substituents of group F; or cycloalkyl; wherein the F group is: -Alk, -lower alkenyl, -lower alkynyl, -Hal, —NH 2 , —NH(Alk), —N(Alk) 2 , —NO 2 , —CN, —OH, —O-Alk, —O—CO-Alk, —SH, —S-Alk, —COO-Alk, —CO-Alk, —CONH 2 , —CONH(Alk), —CON(Alk) 2 , —SO-Alk, —SO 2 -Alk, and —SO 2 NH 2 , with the proviso that (1) when D is 1H-pyrazol-1-yl or 1H-pyrazol-3-yl which may have 1 to 2 substituents and B is 1,4-phenylene, X is a group other than —NH—CO—, and (2) when D is 1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl, n is 0, B is thiophene-2,5-diyl and X is —CO—NH—, A is a group other than 4-chlorophenyl.