Patent ID: 7001921

Claim:
A cell adhesion inhibitory compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is selected from the group consisting of —CO 2 H, —SO 2 R 5 , and —SO 3 H; Y is —CO—; R 1 is selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkyl-substituted alkyl, cycloalkenyl-substituted cycloalkyl, alkoxy, alkenoxy, alkynoxy, alkylamino, alkenylamino, alkynylamino, N-alkylurea-substituted alkyl, alkylcarbonylamino-substituted alkyl, and aminocarbonyl-substituted alkyl; R 2 is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl; R 3 is selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, hydroxy-substituted alkyl, alkoxy-substituted alkyl, amino-substituted alkyl, thiol-substituted alkyl, alkylsulfonyl-substituted alkyl, (hydroxy-substituted alkylthio)-substituted alkyl, thioalkoxy-substituted alkyl, acylamino-substituted alkyl, alkylsulfonylamino-substituted alkyl, (N-(alkyl, alkenyl or alkynyl) or N,N-(dialkyl, dialkenyl, dialkynyl or (alkyl, alkenyl)-amino)carbonyl-substituted alkyl, carboxyl-substituted alkyl, and amino acid side chains selected from arginine, asparagine, glutamine, S-methyl cysteine, methionine and corresponding sulfoxide and sulfone derivatives thereof, glycine, leucine, isoleucine, allo-isoleucine, tert-leucine, norleucine, alanine, ornithine, glutamine, valine, threonine, serine, aspartic acid, beta-cyanoalanine, and allothreonine; R 4 is selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, and alkynyl; R 5 is alkyl, alkenyl, cycloalkyl, cycloalkenyl, or alkynyl; and n is 0, 1 or 2.