Patent ID: 7479495

Claim:
A compound of Formula I, and an enantiomer, diastereomer, tautomer or pharmaceutically acceptable salt thereof wherein: V is —CHR 5 — or —NR 5 ; two of W, X, and Y are each —N═ and the other is —CH═; Z is —N(R 1 )(R 2 ), —S-aryl or S-substituted aryl; —N(R 1 )(R 2 ) taken together may form a heterocyclyl or substituted heterocyclyl or R 1 and R 2 are selected as is alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heterocyclyl or substituted heterocyclyl; R 5 is hydrogen; R 6 is R 7 is hydrogen, alkyl, substituted alkyl, alkoxy or halogen; R 8 is hydrogen; R 9 is —C(O)R 10 , heterocyclyl or substituted heterocyclyl; R 10 is alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heterocyclyl, substituted heterocyclyl or —N(R 31 )(R 32 ); R 31 is hydrogen, alkyl or substituted alkyl; R 32 is hydrogen, alkyl, substituted alkyl, alkoxy, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heterocyclyl or substituted heterocyclyl; R 11 is —N(R 12 )(R 13 ); R 12 is hydrogen, alkyl or substituted alkyl; R 13 is —(CH 2 ) m R 14 ; or —N(R 12 )(R 13 ) taken together form a heterocyclyl or substituted heterocyclyl; m is 0, 1, 2 or 3; R 14 is hydrogen, alkyl, substituted alkyl, —C(O)N(R 31 )(R 32 ), —N(R 33 )C(O)R 34 , aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heterocyclyl, substituted heterocyclyl or R 15 is hydrogen, alkyl or substituted alkyl; R 16 is hydrogen or alkyl; R 33 is hydrogen, alkyl or substituted alkyl; and R 34 is alkyl, substituted alkyl, aryl or substituted aryl.