Patent ID: 7455771

Claim:
An apparatus for dialysis of a biological fluid containing at least one protein-binding substance to be removed, comprising: a biological fluid circuit containing a dialyser, a dialysis fluid circuit containing at least one second dialyser and a means for at least partially solubilizing the protein binding substances to be removed in the dialysis fluid, wherein the dialysis fluid in the dialysis fluid circuit contains an adsorber for the substances to be removed from the biological fluid, and wherein the means for at least partially solubilizing the protein binding substances to be removed comprises a device for adjusting the pH of the dialysis fluid to 8-13 downstream of the second dialyser and a device for adjusting the pH of the dialysis fluid to 2.5-5.5 upstream of the second dialyser, or a device for adjusting the pH of the dialysis fluid to 8-13 upstream of the second dialyser and a device for adjusting the pH of the dialysis fluid to 2.5-5.5 downstream of the second dialyser.