Patent ID: 8178501

Claim:
An antibiotic composition suitable for parenteral injection, comprising: a) A first antibiotic which is a protein synthesis inhibiting antibiotic, wherein said protein synthesis inhibiting antibiotic is an aminoglycoside selected from the group consisting of gentamycin, amikacin, tobramycin and pharmaceutically acceptable salts thereof; b) A second antibiotic which is a non-protein synthesis inhibiting antibiotic, wherein said non-protein synthesis inhibiting antibiotic is a beta lactam cephalosporin selected from the group consisting of cefepime, and pharmaceutically acceptable salts thereof; and c) L-arginine, wherein the L-arginine is provided in an amount effective to stabilize the first antibiotic with the second antibiotic in the composition, wherein said first antibiotic and said second antibiotic are present in a weight ratio of 1:5 to 5:1; wherein said L-arginine is present in a range of 35% to 75% w/w of combined weight of said first antibiotic and said second antibiotic; and wherein said antibiotic composition is present in a reconstitutable dry powder form suitable for reconstitution and for concurrent parenteral administration.