Patent ID: 8877816

Claim:
A compound of formula I: or a salt thereof, wherein: R 1 is chosen from H, (C 1 -C 8 )alkyl and halo(C 1 -C 8 )alkyl; R 2 is chosen from H and halo; Ar 1 is selected from optionally substituted phenyl and optionally substituted heteroaryl, wherein substituted phenyl and substituted heteroaryl refer to phenyl and heteroaryl residues wherein up to three H atoms in each residue are individually replaced with halogen, alkyl, haloalkyl, haloalkoxy, hydroxy, loweralkoxy, oxaalkyl, carboxy, carboalkoxy, carboxamido, alkylaminocarbonyl, alkoxycarbonyl, alkoxycarbonylamino, acyl, alkoxyalkyl, benzenesulfonyl, cyano, carbonyl, nitro, amino, urea, alkylurea, hydroxyalkyl, alkylamino, dialkylamino, aminoalkyl, (alkyl)(aryl)aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, dialkylaminoalkoxy, heterocyclylalkoxy, mercapto, alkylthio, alkylsulfinyl, alkylsulfonyl, acylamino, acylaminoalkyl, acylaminoalkoxy, amidino, acetoxy, sulfoxide, alkylsulfoxide, sulfone, alkylsulfone, sulfonylamino, alkylsulfonylamino, aryl, heterocyclyl, hydroxyimino, alkoxyimino, aminosulfonyl, trityl, amidino, guanidino, ureido, benzyloxyphenyl, benzyl, heteroaryl, heterocyclylalkyl, phenoxy, benzyloxy, heteroaryloxy, —NH(tBoc), or —NHSO 2 NH 2 ; and Ar 2 is selected from: (a) phenyl substituted in the para position with a single substituent selected from halogen, alkyl, haloalkyl, haloalkoxy, hydroxy, loweralkoxy, oxaalkyl, carboxy, carboalkoxy, carboxamido, alkylaminocarbonyl, alkoxycarbonyl, alkoxycarbonylamino, acyl, alkoxyalkyl, benzenesulfonyl, cyano, carbonyl, nitro, amino, urea, alkylurea, hydroxyalkyl, alkylamino, dialkylamino, aminoalkyl, (alkyl)(aryl)aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, dialkylaminoalkoxy, heterocyclylalkoxy, mercapto, alkylthio, alkylsulfinyl, alkylsulfonyl, acylamino, acylaminoalkyl, acylaminoalkoxy, amidino, acetoxy, sulfoxide, alkylsulfoxide, sulfone, alkylsulfone, sulfonylamino, alkylsulfonylamino, aryl, heterocyclyl, hydroxyimino, alkoxyimino, aminosulfonyl, trityl, amidino, guanidino, ureido, benzyloxyphenyl, benzyl, heteroaryl, heterocyclylalkyl, phenoxy, benzyloxy, heteroaryloxy, —NH(tBoc), and —NHSO 2 NH 2 ; and (b) pyridinyl substituted in the para position with a single substituent selected from halogen, alkyl, haloalkyl, haloalkoxy, hydroxy, loweralkoxy, oxaalkyl, carboxy, carboalkoxy, carboxamido, alkylaminocarbonyl, alkoxycarbonyl, alkoxycarbonylamino, acyl, alkoxyalkyl, benzenesulfonyl, cyano, carbonyl, nitro, amino, urea, alkylurea, hydroxyalkyl, alkylamino, dialkylamino, aminoalkyl, (alkyl)(aryl)aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, dialkylaminoalkoxy, heterocyclylalkoxy, mercapto, alkylthio, alkylsulfinyl, alkylsulfonyl, acylamino, acylaminoalkyl, acylaminoalkoxy, amidino, acetoxy, sulfoxide, alkylsulfoxide, sulfone, alkylsulfone, sulfonylamino, alkylsulfonylamino, aryl, heterocyclyl, hydroxyimino, alkoxyimino, aminosulfonyl, trityl, amidino, guanidino, ureido, benzyloxyphenyl, benzyl, heteroaryl, heterocyclylalkyl, phenoxy, benzyloxy, heteroaryloxy, —NH(tBoc), and —NHSO 2 NH 2 .