Patent ID: 8916523

Claim:
A method of therapeutic treatment of myocardial fibrosis, or an associated condition, in a subject, wherein the method comprises administering to a subject in need thereof a composition comprising one or more VIP fragments selected from the group consisting of: VIP(6-10) (SEQ ID NO: 66), VIP(6-12) (SEQ ID NO: 68), VIP(6-16) (SEQ ID NO: 72), VIP(6-20) (SEQ ID NO: 76), VIP(6-24) (SEQ ID NO: 80), and conservative substitutions thereof that do not alter the biological activity of the fragment, wherein the associated condition is selected from the group consisting of: hypertension, diabetes, myocarditis, ischaemic heart disease, left ventricular hypertrophy, diastolic dysfunction, cardiomyopathy, left ventricular dysfunction, congestive cardiac failure, Conn's Syndrome and Phaeochromocytoma.