Patent ID: 6894175

Claim:
A 2-decarboxy-2-phosphinico prostaglandin derivative having a structure selected from the group consisting of: wherein bond a is selected from the group consisting of a single bond, a trans double bond, and a triple bond; R 1 is selected from the group consisting of a hydrogen atom, a monovalent hydrocarbon group having 1 to 4 carbon atoms, and a monovalent heterogenous group having 1 to 4 member atoms, wherein the member atom directly adjacent to P in said heterogenous group is not oxygen; R 2 is selected from the group consisting of a hydrogen atom, a monovalent hydrocarbon group, a substituted monovalent hydrocarbon group, a monovalent heterogeneous group, a substituted monovalent heterogeneous group, a carbocyclic group, a substituted carbocyclic group, a heterocyclic group, a substituted heterocyclic group, an aromatic group, a substituted aromatic group, a heteroaromatic group, a substituted heteroaromatic group, a mono- or polyvalent inorganic cation and a mono- or polyvalent organic cation; R 3 is selected from the group consisting of an oxygen atom, a sulfur atom, and NH; R 4 is selected from the group consisting of an oxygen atom and a sulfur atom; R 5 is a divalent group selected from the group consisting of a hydrocarbon group, a substituted hydrocarbon group, a heterogeneous group, and a substituted heterogeneous group; R 6 is nil or a divalent group selected from the group consisting of —CH 2 —, —C(O)— and —C(R 10 )OR 10 )—; R 7 is nil or a divalent group having the formula —(CD(D)) p —X—(CD(D)) q —, wherein p is an integer from 0 to 3 and q is an integer from 0 to 3, X is selected from the group consisting of an oxygen atom, a divalent hydrocarbon group, a sulfur atom, SO, SO 2 , and ND, and each D is independently selected from the group consisting of a hydrogen atom, a monovalent hydrocarbon group of 1 to 4 carbon atoms, and a monovalent heterogenous group of 1 to 4 member atoms; R 8 is selected from the group consisting of a hydrocarbon group, a substituted hydrocarbon group, a heterogenous group, a substituted heterogenous group, a carbocyclic group, a substituted carbocyclic group, a heterocyclic group, a substituted heterocyclic group, an aromatic group, a substituted aromatic group, a heteroaromatic group, and a substituted heteroaromatic group; R 9 is selected from the group consisting of a hydrogen atom, a monovalent hydrocarbon group of 1 to 4 carbon atoms, and a monovalent heterogenous group of 1 to 4 member atoms; and R 14 is independently selected from the group consisting of nil, a hydrogen atom, a halogen atom, a monovalent hydrocarbon group of 1 to 4 carbon atoms, and a monovalent heterogenous group of 1 to 4 member atoms wherein said heterogenous group is a saturated or unsaturated chain containing from 1 to 18 member atoms that comprises at least carbon and one heteroatom and wherein said saturated or unsaturated chain is straight or branched.