Patent ID: 7110807

Claim:
A system for synthesizing an image slice of a selected object from multiple projected object images created by irradiating the object with a source of radiation, comprising: a. a fiducial reference located at a fixed position relative to the selected object to provide constraint for a number of degrees of freedom correlated to a number of degrees of freedom of the system, the fiducial reference comprising at least a first and a second identifiable reference marker disposed in a fixed position relative to one another, the first marker configured to permit alignment of the multiple images for construction of a tomosynthetic slice and the second reference marker configured to permit projective warping of a projected image from an actual projection plane to a virtual projection plane for construction of a tomosynthetic slice; b. a recording medium for recording at least one projected image of the fiducial reference and a region of interest of the selected object; and c. an image synthesizer for analyzing parameters related to positions and sizes of the images detected upon said recording medium to produce image translation data, and for reconstructing a tomographic slice from the object images and the translation data; wherein the fiducial reference, the source of radiation, and the recording medium are configured to be arbitrarily movable relative to one another.