Patent ID: 6960597

Claim:
A compound of Formula (I): wherein Y is selected from the group consisting of a bond, —C(O)—, —C(O)O—, —C(O)NH— and —SO 2 —; R 1 is R 7 or R 8 ; R 2 , R 3 , R 4 and R 5 are independently hydrogen or C 1-8 alkyl; wherein C 1-8 alkyl is optionally substituted with one to three substituents independently selected from R 9 ; R 6 is optionally present and is one to three substituents independently selected from the group consisting of halogen, C 1-8 alkoxy, R 10 , R 12 , —N(R 11 )C(O)—R 10 , —N(R 11 )C(O)—R 12 , —N(R 11 )SO 2—R 10 , —N(R 11 )SO 2—R 12 , —N(R 11 )C(O)—N(R 11 , R 10 ), —N(R 11 )C(O)—N(R 11 , R 12 ), —N(R 11 )C(O)—N(R 12 , R 17 ), —C(O)—N(R 11 , R 10 ), —C(O)—N(R 11 , R 12 ), —C(O)—N(R 12 , R 17 ), —OC(O)—N(R 11 , R 10 ), —OC(O)—N(R 11 , R 12 ), —OC(O)—N(R 12 , R 17 ), —OC(O)—R 10 , —OC(O)—R 12 , —O—R 10 and R 10 —(C 1-8 )alkoxy; R 7 , R 9 R 10 and R 14 are independently selected from the group consisting of cycloalkyl, heterocyclyl, aryl, and heteroaryl optionally substituted with one to five substituents independently selected from the group consisting of halogen, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 1-8 alkoxy, C 1-8 alkylcarbonyl, C 1-8 alkoxycarbonyl, carboxyl, aryl, heteroaryl, arylcarbonyl, heteroarylcarbonyl, arylsulfonyl, amino, N—(C 1-8 alkyl)amino, N,N—(C 1-8 dialkyl)amino, —CF 3 and —OCF 3 ; wherein cycloalkyl and heterocyclyl are optionally substituted with one to three oxo substituents; and, wherein the aryl and heteroaryl substituents and the aryl portion of the arylcarbonyl substituent are optionally substituted with one to five substituents independently selected from the group consisting of halogen, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 1-8 alkoxy, carboxyl, amino, N—(C 1-8 alkyl)amino, N,N—(C 1-8 dialkyl)amino, —CF 3 and —OCF 3 ; R 8 , R 12 , R 13 and R 17 are independently selected from the group consisting of C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, and (halo) 1-3 (C 1-8 )alkyl; wherein C 1-8 alkyl, C 2-8 alkenyl and C 2-8 alkynyl are optionally substituted on a terminal carbon with one to three substituents independently selected from R 14 ; R 11 is hydrogen or C 1-8 alkyl; A is C 1-4 alkylene optionally substituted with one to two substituents independently selected from R 13 ; B 1 and B 2 are independently selected from the group consisting of C 1-2 alkylene and C 2 alkenylene optionally substituted with one to two substituents independently selected from the group consisting of halogen, hydroxy, hydroxy(C 1-8 )alkyl, hydroxy (C 1-8 ) alkoxy, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 1-8 alkoxy, carboxyl, amino, N—(C 1-8 alkyl)amino, N,N—(C 1-8 dialkyl)amino, —CF 3 and —OCF 3 ; and pharmaceutically acceptable salts, racemic mixtures, diastereomers and enantiomers thereof.