Patent ID: 8105790

Claim:
A method for identifying aspirin response in a subject comprising: administering to the subject a first dose of aspirin; collecting a urine sample from the subject; determining an amount of two thromboxane A 2 metabolites in the urine sample, wherein the determining the amount of thromboxane A 2 metabolites comprises using a monoclonal antibody capable of binding to 11-dehydro thromboxane B 2 and 11-dehydro-2,3-dinor Thromboxane B 2 ; normalizing the amount of the two thromboxane A 2 metabolites to an amount of a standard protein in the subject's urine to obtain a first thromboxane A 2 metabolite/standard protein ratio; and comparing the first thromboxane A 2 metabolite/standard protein ratio to a threshold ratio value wherein a thromboxane A 2 metabolite/standard protein value below the threshold value indicates aspirin responsiveness in the subject.