Patent ID: 8303986

Claim:
A controlled release tablet comprising an amount of ropinirole, inclusive of pharmaceutically acceptable salts, which tablet exhibits a release rate over approximately 24 hours in vitro as measured using equipment 2, paddle (USP XXIII), working at 100 rpm and utilizing as dissolution fluid 500 ml of an aqueous buffer solution of citrate (pH 4.0) at 37° C., and which tablet has an in vitro dissolution profile; wherein the release rate of ropinirole as a percentage is independent of the amount of ropinirole in said tablet, and wherein the tablet comprises one active layer having a weight, said active layer containing: (i) 0.75 mg to 12.0 mg ropinirole, inclusive of pharmaceutically acceptable salts, measured as ropinirole base present; (ii) hydrophilic polymeric substances that gel and/or swell and/or erode upon contact with aqueous liquids; (iii) lipophilic substances; and (iv) adjuvant substances; wherein the hydrophilic polymeric substances and the lipophilic substances contained in said active layer, expressed as a weight ratio (w/w), ranges from 10:1 to 0.5:1.