Patent ID: 8067438

Claim:
A racemate, diastereoisomer, or optical isomer of a compound of formula (I): wherein: B is (C 2-8 )alkyl, (C 3-7 )cycloalkyl or (C 1-3 )alkyl-(C 3-7 )cycloalkyl, a) wherein said alkyl, cycloalkyl, and alkyl-cycloalkyl may be mono-, di- or tri-substituted with (C 1-3 )alkyl; and b) wherein said alkyl, cycloalkyl, and alkyl-cycloalkyl may be mono- or di-substituted with substituents selected from hydroxy and O—(C 1-4 )alkyl; and c) wherein each of said alkyl groups may be mono-, di- or tri-substituted with fluorine or mono-substituted with chlorine or bromine; and d) wherein in each of said cycloalkyl groups being 5-, 6- or 7-membered, one or two —CH 2 -groups not being directly linked to each other may be replaced by —O— such that the O-atom is linked to the group X via at least two C-atoms; X is O or NH; R 3 is (C 2-6 )alkyl or (C 3-7 )cycloalkyl, both of which being optionally substituted with 1 to 3 substituents selected from (C 1-4 )alkyl; L 0 is —OH, —OCH 3 , halogen or —N(CH 3 ) 2 ; L 1 and L 2 are each independently selected from: halogen, —CH 3 , —C 2 H 5 , —OCH 3 , —OC 2 H 5 , —OC 3 H 7 , —OCH(CH 3 ) 2 , CF 3 , —SMe, —SOMe, and SO 2 Me, whereby either L 1 or L 2 may be H; R 2 is R 20 , —NHCOR 20 , —NHCOOR 20 , —NHR 21 and —NHCONR 21 R 23 , wherein R 20 is selected from (C 1-8 )alkyl, (C 3-7 )cycloalkyl, (C 1-3 )alkyl-(C 3-7 )cycloalkyl, wherein said cycloalkyl and alkyl-cycloalkyl may be mono-, di- or tri-substituted with (C 1-3 )alkyl; and R 21 is H or R 20 as defined above; and R 23 is H or methyl; R 1 is ethyl or vinyl; and R C is hydroxy; or a pharmaceutically acceptable salt or ester thereof.