Patent ID: 7153993

Claim:
A method of preparing a pharmaceutically acceptable tablet comprising isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid, which orthorhombic crystalline form is substantially free of monoclinic crystalline forms, the method comprising: (a) dry blending the isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid, which orthorhombic crystalline form is substantially free of monoclinic crystalline forms, with pharmaceutically acceptable excipients to provide a mixture; (b) granulating the mixture with binding solution to provide a wet mixture; (c) drying the wet mixture; (d) milling the dried mixture; and (e) tableting the milled mixture to form a tablet.