Patent ID: 7745414

Claim:
A glucopyranosyl-substituted benzonitrile derivative selected from the list according to formula II, III, or i.2, wherein R 3 is cyclopentyloxy, cyclobutyloxy, cyclohexyloxy, tetrahydropyran-4-yloxy, 1-acetyl-piperidin-4-yloxy or C 1-3 -alkyloxy, and R′ denotes H, C 1-4 -alkyl, (C 1-18 -alkyl)carbonyl, (C 1-18 -alkyl)oxycarbonyl, arylcarbonyl or aryl-(C 1-3 -alkyl)-carbonyl, wherein the alkyl or aryl groups may be mono- or polysubstituted by halogen; R 8a , R 8b , R 8c , R 8d independently of one another denote hydrogen or an allyl group, a benzyl group, a (C 1-4 -alkyl)carbonyl, (C 1-4 -alkyl)oxycarbonyl, arylcarbonyl, aryl-(C 1-3 -alkyl)-carbonyl and aryl-(C 1-3 -alkyl)-oxycarbonyl or a R a R b R c Si group or a ketal or acetal group, particularly an alkylidene or arylalkylidene ketal or acetal group, while in each case two adjacent groups R 8a , R 8b , R 8c , R 8d may form a cyclic ketal or acetal group or a 1,2-di(C 1-3 -alkoxy)-1,2-di(C 1-3 -alkyl)-ethylene bridge, while the above-mentioned ethylene bridge forms, together with two oxygen atoms and the two associated carbon atoms of the pyranose ring, a substituted dioxane ring, particularly a 2,3-dimethyl-2,3-di(C 1-3 -alkoxy)- 1,4-dioxane ring, and while alkyl, allyl, aryl and/or benzyl groups may be mono- or polysubstituted by halogen or C 1-3 -alkoxy, and while benzyl groups may also be substituted by a di-(C 1-3 -alkyl)amino group; and R a , R b , R c independently of one another denote C 1-4 -alkyl, aryl or aryl-C 1-3 -alkyl, wherein the aryl or alkyl groups may be mono- or polysubstituted by halogen; while by the aryl groups mentioned in the definition of the above groups are meant phenyl or naphthyl groups; and Alk denotes C 1-4 -alkyl.