Patent ID: 8227604

Claim:
A compound having the structure (I) wherein A is an optionally heterocyclic aromatic ring system containing from 1 to 4 aromatic or heteroaromatic rings, optionally fused; comprises an aromatic ring system wherein X and Y are moieties which complete a 5 or 6 membered aromatic ring optionally containing N, O, S, or Se heteroatoms; R 2 is a C 1-10 hydrocarbon group substituent or two R 2 together may form a fused ring system, said hydrocarbon group and said fused ring system optionally containing one or more O, N, S, or Se heteroatoms, or R 2 is a hydroxyl or amino group, o is an integer from 0 to 4, the upper limit of o bounded by the number of available substitutent sites on said optionally heterocyclic 5 or 6 membered aromatic ring structure; n is 0 or 2; R 1 is an organyl group selected from the group consisting of C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 4-8 cycloalkyl, C 4-8 cycloalkenyl, C 6-10 aryl, each of the foregoing alkyl, alkenyl, alkynyl, cycloalkyl, etc. groups optionally halo substituted and/or substituted by —CN, C 1-4 lower alkoxy, C 1-4 acyloxy, C 1-4 acyl, or —C(O)—R 4 ; —R 5 —NH—SO 2 —NR 4 , where R 5 is C 1-8 alkylene and r is 2 or 3, with the proviso that when r is 3, the nitrogen of the NR 4 , group will bear a positive formal charge; —R 5 —NH—C(O)—R 4 ; —R5—NR r 4 —R5—Ar where Ar is an aryl ring system, optionally including one or more O, N, S, or Se heteroatoms and wherein R 1 , together with (CH 2 ) p may form an alicyclic sic membered ring, and wherein R 1 , together with the six membered alicyclic ring of structure (I) may form a fused six membered alicyclic ring; p is 1 to 4; wherein one (CH 2 ) n group may be replaced by O, or S, or Se; or a pharmaceutically acceptable salt, ester, carbamate, or amide thereof.