Patent ID: 8399415

Claim:
A method for reducing skin discomfort and/or pain due to an irritating cosmetic agent in a cosmetic composition comprising administering to skin in need thereof a cosmetic composition which comprises a) an oligopeptide according to formula (I) and/or (II): (SEQ ID NO: 1) R 1 -Tyr-Pro-Trp-Phe-NH 2 (I) (SEQ ID NO: 2) R 1 -Tyr-Pro-Phe-Phe-NH 2 (II) wherein R 1 is linked to the NH 2 -group of the amino-terminal portion of Tyr and is selected from the group consisting of: (i) —H; (ii) a linear saturated or unsaturated or branched saturated or unsaturated acyl group having 1 to 24 carbon atoms, which acyl group can be functionalized by a —OH, —SH, —COOH or —CONH 2 group; and (iii) a sterol or a sphingolipid group which is linked to the amino terminal portion of Tyr by a bifunctional linker; b) an irritating cosmetic agent; and c) optionally, an additive or auxiliary suitable for use in a cosmetic composition; wherein the oligopeptide is present in the composition in an amount sufficient to reduce discomfort and/or pain due to the irritating cosmetic agent when the cosmetic composition is administered cutaneously.