Patent ID: 8436036

Claim:
A compound of formula I: including any possible stereoisomers thereof, wherein: R and R 1 , independently from one another, are benzoyl optionally substituted with one, two or three substituents each independently selected from halo and C 1 -C 6 alkyl, or —C(═O)-Het wherein Het is optionally substituted with one or two substituents independently selected from C 1-4 alkyl, or a group of formula —C(═O)—CH(R x )—R 6 , benzyloxycarbonyl, C 1 -C 6 alkyloxycarbonyl, a group of formula H 2 N—CH(R 7 )—C(═O)—, a group of formula R 8 —O—C(═O)—HN—CH(R 7 )—C(═O)—, or —C(═O)—C(═O)-phenyl; R 6 is C 1 -C 4 alkyl, C 3-6 cycloalkyl, benzyl or phenyl wherein the phenyl may be optionally substituted with one, two or three substituents each independently selected from halo, C 1 -C 6 alkyl, methoxy, trifluoromethoxy or two substituents on adjacent ring atoms, together with the phenyl ring, form a benzodioxole, and, wherein the C 1 -C 4 alkyl is optionally substituted with mono- or diC 1 -C 4 alkylamino, phenylsulphonyl, Het, and, wherein benzyl is optionally substituted with one, two or three substituents each independently selected from halo, methoxy; R x is selected from hydrogen, hydroxy, C 1 -C 6 alkoxy, amino, mono- or diC 1 -C 6 alkylamino, pyrrolidinyl, piperidinyl, morpholinyl, imidazolyl, C 1 -C 6 alkylcarbonylamino or C 1 -C 6 alkyloxycarbonylamino; Het is a heterocyclic group comprising one or two heteroatoms selected from O and N and having 4 to 7 ring atoms wherein said heterocyclic ring is connected to the carbonyl carbon by a ring carbon atom and wherein at least one of said heteroatoms is adjacent to said ring carbon atom, R 2 and R 3 , independently from one another, are hydrogen, hydroxyl, C 1 -C 4 alkyl or halo; R 4 and R 5 , independently from one another, are hydrogen, C 1 -C 4 alkyl, halo or methoxy; each R 7 independently is hydrogen, phenyl, or C 1 -C 4 alkyl optionally substituted with methoxy or phenyl; and, R 8 is C 1 -C 4 alkyl or benzyl; or a pharmaceutically acceptable salt thereof.