Patent ID: 8147874

Claim:
Coated pellets, which comprise an active pharmaceutical ingredient that has a solubility of at most 20 mg ml −1 in pure water at 23° C.; release at least 80% of said active ingredient under in vitro conditions in phosphate buffer at pH 5.0 after 30 minutes, and are coated with a composition consisting of a wax (A) and a hydrogel former (B); wherein said wax (A) has at least one characteristic selected from the group consisting of: (i) an HLB value of ≦5; (ii) a melting range of ≧60° C.; (iii) a solidification range Δ of less than 35° C., and (iv) a density of ≧0.80 g cm −3 ; and wherein the hydrogel former (B) is selected from the group consisting of carbomer, guar gum, L-HPC, and xanthan gum.