Patent ID: 8513436

Claim:
A compound of the formula: wherein: the atoms labeled 1 and 2 are connected either by a double bond or an epoxidized double bond; n is 1 or 2; X is —CN, —CF 3 , or —C(O)R a , wherein R a is —OH, alkoxy (C≦6) , alkylamino (C≦6) , dialkylamino (C≦6) , or —NHS(O) 2 -alkyl (C1-4) ; R 1 and R 2 are each independently hydrogen, hydroxy, halo, or amino; or alkyl (C≦12) , alkenyl (C≦12) , alkynyl (C≦12) , aryl (C≦12) , aralkyl (C≦12) , heteroaryl (C≦12) , heterocycloalkyl (C≦12) , acyl (C≦12) , alkoxy (C≦12) , aryloxy (C≦12) , aralkoxy (C≦12) , heteroaryloxy (C≦12) , acyloxy (C≦12) , alkylamino (C≦12) , dialkylamino (C≦12) , arylamino (C≦12) , aralkylamino (C≦12) , heteroarylamino (C≦12) , amido (C≦12) , or a substituted version of any of these groups; or R 1 and R 2 are taken together and are alkanediyl (C≦12) , alkenediyl (C≦12) , alkoxydiyl (C≦12) , alkylaminodiyl (C≦12) , or a substituted version of any of these groups; R 3 is absent, hydrogen; or alkyl (C≦12) , alkenyl (C≦12) , alkynyl (C≦12) , aryl (C≦12) , aralkyl (C≦12) , heteroaryl (C≦12) , heterocycloalkyl (C≦12) , acyl (C≦12) or a substituted version of any of these groups; provided that R 3 is absent when and only when the atom to which it is bound forms part of a double bond; R 5 is absent, hydrogen; or alkyl (C≦12) , alkenyl (C≦12) , alkynyl (C≦12) , aryl (C≦12) , aralkyl (C≦12) , heteroaryl (C≦12) , heterocycloalkyl (C≦12) , acyl (C≦12) or a substituted version of any of these groups; provided that R 5 is absent when and only when the atom to which it is bound forms part of a double bond; and R 6 is hydrogen, hydroxy, amino, halo, cyano, or oxo; or alkyl (C≦12) , alkenyl (C≦12) , alkynyl (C≦12) , aryl (C≦12) , aralkyl (C≦12) , heteroaryl (C≦12) , heterocycloalkyl (C≦12) , acyl (C≦12) , alkoxy (C≦12) , aryloxy (C≦12) , aralkoxy (C≦12) , heteroaryloxy (C≦12) , acyloxy (C≦12) , alkylamino (C≦12) , dialkylamino (C≦12) , arylamino (C≦12) , aralkylamino (C≦12) , heteroarylamino (C≦12) , amido (C≦12) , or a substituted version of any of these groups; or a pharmaceutically acceptable salt or tautomer thereof.