Patent ID: 8712499

Claim:
A method of producing a high-resolution quantitative oxygen image of an in vivo sample comprising: determining at a 90°-τ-180° Hahn echo-based single point imaging (ESPI) oxygen imaging system ( 12 ) executing on at least one processor ( 24 ) a spatially-resolved relaxivity between each of a plurality of logarithms of spatially- resolved spin intensities of a first ESPI image and each of a plurality of logarithms of spatially-resolved spin intensities of a second ESPI image; and determining at the ESPI oxygen imaging system ( 12 ) a spatially-resolved oxygen content by interpolating a reference oxygen concentration from a predetermined table comprising a plurality of reference oxygen concentrations as a function of the spatially-resolved relaxivity, and mapping each spatially-resolved oxygen content onto a corresponding spatial location within a sample image to produce a high-resolution quantitative oxygen image.