Patent ID: 7939698

Claim:
A method for carrying out a Grignard reaction comprising mixing at least two fluids, one of the at least two fluids comprising a compound (1 st reactant) able to react with a Grignard reagent in a Grignard type reaction, and another fluid comprising the Grignard reagent (2 nd reactant), and optionally further fluids, said mixing taking place in a microreactor comprising at least one flow path for one of the at least two fluids comprising either the 1 st or 2 nd reactant, said flow path(s) comprising at least two reaction regions, each reaction region comprising an injection point for feeding the other one of the two fluids comprising either the 2 nd or 1 st reactant with the proviso that the reactant in the at least one flow path and the reactant in the injection point are not the same, a mixing zone in which the at least two fluids contact each other and a reaction zone, and wherein the microreactor optionally provides one or more additional residence time volumes, and wherein in said method one of the at least two fluids comprising either the 1 st or 2 nd reactant establishes a first flow and wherein the other one of the at least two fluids comprising either the 2 nd or 1 st reactant is injected into said first flow at least at two injection points along said flow path(s) in a way such that at each injection point only a fraction of the amount necessary to reach completion of the Grignard type reaction is injected.