Patent ID: 7786109

Claim:
A compound of formula I: wherein: A is CH or N; r is 2; R 1 is selected from the group consisting of hydrogen, lower alkyl, lower hydroxyalkyl, lower alkoxyalkyl, lower halogenalkyl, lower hydroxyhalogenalkyl, lower alkanoyl, lower alkylsulfonyl, lower phenylsulfonyl, lower cycloalkylalkyl, lower phenylalkyl, wherein the phenyl ring may be unsubstituted or substituted with one or two groups independently selected from lower alkyl, cyano, halogen, lower halogenalkyl, lower alkoxy and lower hydroxyalkyl, lower heteroarylalkyl, wherein the heteroaryl ring may be unsubstituted or substituted with one or two groups independently selected from lower alkyl, halogen, phenyl, lower alkoxy and lower hydroxyalkyl, lower heterocyclylalkyl, wherein the heterocyclyl ring may be unsubstituted or substituted with one or two groups independently selected from lower alkyl, halogen, phenyl, lower alkoxy and lower hydroxyalkyl, and —CH 2 —CO—NR 14 R 15 , wherein R 14 and R 15 independently from each other are selected from the group hydrogen, lower alkyl and phenyl unsubstituted or substituted with one or two groups independently selected from lower alkyl, halogen, lower halogenoalkoxy and lower hydroxyalkyl, or R 14 and R 15 together with the nitrogen atom to which they are attached form a 4-, 5-, 6- or 7-membered heterocyclic ring optionally containing a further heteroatom selected from nitrogen, oxygen or sulfur, a sulfinyl group or a sulfonyl group, said heterocyclic ring being unsubstituted or substituted by one, two or three groups independently selected from lower alkyl, halogen, halogenalkyl, hydroxy, lower hydroxyalkyl, lower alkoxy, oxo, phenyl, benzyl, pyridyl and carbamoyl; R 2 , R 2′ , R 3 and R 3′ independently from each other are selected from the group consisting of hydrogen, lower alkyl, lower hydroxyalkyl and lower alkoxyalkyl; R 4 is selected from the group consisting of hydrogen and halogen; R 5 is hydrogen or halogen; G is a group selected from wherein m is 0, 1 or 2; R 6 is selected from lower alkyl, cycloalkyl, lower cycloalkylalkyl and lower phenylalkyl; n is 0, 1 or 2; R 7 is lower alkyl; B is selected from CR 13 R 13′ , O and S; R 8 , R 8′ , R 9 , R 9′ , R 10 , R 10′ , R 13 and R 13′ independently from each other are selected from the group consisting of hydrogen, lower alkyl, hydroxy, halogen and dialkylamino, or R 9 and R 13 together form a double bond; p is 0, 1 or 2; q is 0, 1 or 2; R 11 is lower alkyl; R 12 is lower alkyl; or a pharmaceutically acceptable salt thereof.