Patent ID: 8809352

Claim:
A compound of formula (Ib): wherein R 1b is H, NO 2 , SO 2 CF 3 , SO 2 (C 1 -C 6 )alkyl, halo-substituted (C 1 -C 6 )alkyl, halogen, (C 3 -C 14 )cycloalkyl, or CN; R 2b is a divalent bicyclic radical selected from: wherein R 2b may unsubstituted or substituted with one or more of halogen, OH, (C 1 -C 6 )alkyl, halo-substituted (C 1 -C 6 )alkyl, CN or NH 2 ; R 3b and R 4b are independently selected from hydrogen, methyl and isopropyl; or R 3b and R 4b together form a group selected from morpholino; piperidinyl, pyrrolidinyl, 8-oxa-3-azabicyclo[3.2.1]octan-3-yl and piperazinyl substituted with a group selected from methyl and ethyl; R 5b is selected from: which is unsubstituted or substituted with (C 1 -C 6 )alkyl, halogen, OH, (C 1 -C 3 )alkoxy, NH 2 , or deuterium; R 6b is L b -R 8b ; R 7b is halogen; L b is selected from methylene, ═CH— and —CH(CH 3 )— wherein L b is unsubstituted or substituted by one or more (C 1 -C 4 )alkyl, halo-substituted(C 1 -C 4 )alkyl, or (C 3 -C 8 )cycloalkyl; R 8b is selected from phenyl, biphenyl, 4,4-dimethyl-2,3,4,5-tetrahydro-1,1′-biphenyl and 3,3-dimethyl-2,3,4,5-tetrahydro-1,1′-biphenyl; each of which is unsubstituted or substituted with one or more substituents each independently selected from halogen, methoxy, OH, (C 1 -C 6 )alkyl, halo-substituted(C 1 -C 6 )alkyl, or CN; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable salt thereof.