Patent ID: 7482362

Claim:
A method of suppressing T-cell proliferation in a living animal body by administering to the living animal body a therapeutically-effective amount of a compound of the formula I wherein R1 is a straight or branched chain, saturated or ethylenically-unsaturated aliphatic hydrocarbyl group containing from 1 to 18 carbon atoms which may optionally be substituted by one or more substituent groups selected from halo, 1-6C alkoxy, carboxy, 1-6C alkoxycarbonyl and NR 6 R 7 , wherein each of R 6 and R 7 is independently selected from H and 1-6C alkyl or R 6 and R 7 together with the N atom to which they are attached form a saturated heterocyclic group selected from piperidino, piperazino and morpholin; R 2 is group selected from H, —OH, halo, —CHO, —CO 2 H and CONHR 8 wherein R 8 is H or a 1-6C alkyl; each of R 3 , R 4 and R 5 is independently selected from H, —CH 3 , —OCH 3 and halo; or a non-toxic pharmaceutically-acceptable salt thereof; wherein said suppression of T-cell proliferation treats autoimmune diseases.