Patent ID: 7749445

Claim:
An apparatus for assessing purity of a bioprocess fluid, comprising: a) a fluid chamber having at least one opening for the bioprocess fluid to enter; b) a flexural plate wave device defining at least a portion of at least one interior surface of the fluid chamber and capable of being coated with a plurality of first capture agents capable of binding one or more biological markers in the bioprocess fluid; c) a monitoring device to monitor at least one signal output by the flexural plate wave device; d) a plurality of magnetic particles capable of being coated with a plurality of second capture agents capable of binding one or more biological markers in the bioprocess fluid; and e) a retractable source of magnetic flux positioned external to the fluid chamber close to the at least one interior surface of the fluid chamber to create a magnetic field gradient to selectively attract magnetic particles toward a surface of the flexural plate wave device.