Patent ID: 6890934

Claim:
A sulfonamide compound of formula (I): wherein R 1 is an aryl or an group unsaturated 5- or 6-membered heteromonocyclic group having 1 to 4 nitrogen atom(s), which is substituted by at least one substituent selected from the group consisting of: (1) aryl, (2) pyrrolyl, pyrrolidinyl, oxazolidinyl, thienyl, or furanyl, each of which may be optionally substituted by oxo or halogen, (3) halogen, (4) halo(lower)alkyl, (5) lower alkoxy optionally substituted by cyclo(lower)alkyl, (6) amino optionally substituted by at least one substituent selected from the group consisting of lower alkyl optionally substituted by cyclo(lower)alkyl, protected carboxy, acyl, lower alkylcarbamoyl, and lower alkanesulfonyl, (7) nitro and (8) lower alkynyl optionally substituted by aryl; R 2 is a lower alkyl or lower alkoxy; R 3 is a hydrogen or lower alkyl; R 4 is: a lower alkenyl optionally substituted by aryl or unsaturated 5- or 6-membered heteromonocyclic group having 1 to 4 nitrogen atom(s), aryl optionally substituted by carboxy or protected carboxy, lower alkyl optionally substituted by acyloxy, amino optionally substituted by lower alkyl, or unsaturated 5- or 6-membered heteromonocyclic group having one sulfur atom or one oxygen atom optionally substituted by halogen; and A is a lower alkylene; or a salt, solvate, or hydrate of a compound of formula (I), with the proviso that A is not methylene and R 1 is not: wherein X is halogen, Y is C or N, and R 5 is pyrrolyl, furyl, or amino substituted by protected carboxy and optionally substituted by lower alkyl.