Patent ID: 7993878

Claim:
A polynucleotide construct that encodes an IL-1β binding molecule or antigen-binding fragment thereof comprising, a) a heavy chain variable domain comprising amino acids 20-137 of the amino acid sequence set forth as SEQ ID NO:1; b) a light chain variable domain comprising amino acids 20-126 of the amino acid sequence set forth as SEQ ID NO:2; c) the three CDRs of the amino acid sequence set forth as SEQ ID NO:1 and the three CDRs of the amino acid sequence set forth as SEQ ID NO:2; or d) a heavy chain variable domain comprising amino acids 20-137 of the amino acid sequence set forth as SEQ ID NO:1 and a light chain variable domain comprising amino acids 20-126 of the amino acid sequence set forth as SEQ ID NO:2.