Patent ID: 7273874

Claim:
A compound of the formula I: wherein: R 1 and R 2 are the same or different and are selected from the group consisting of CR 16 R 17 and CR 18 R 19 ; R 3 and R 4 are: (a) independently selected from the group consisting of H, OH, O(C 1 to C 6 alkyl), O(substituted C 1 to C 6 alkyl), O(acyl), O(aryl), O(substituted aryl), and halogen; or (b) taken together to form a double bond to O; R 5 , R 6 , and R 7 are independently selected from the group consisting of H, OH, and OCH 3 ; R 8 and R 9 are connected though a (i) single bond and are CH 2 or (ii) double bond and are CH; R 15 is selected from the group consisting of C═O, CHOH, and CH 2 ; R 16 and R 17 are independently selected from the group consisting of H, C 1 to C 6 alkyl, C 1 to C 6 substituted alkyl, aryl, substituted aryl, acyl, CF 3 , CN, and NO 2 ; R 18 and R 19 are independently selected from the group consisting of H, C 1 to C 6 alkyl, C 1 to C 6 substituted alkyl, aryl, substituted aryl, acyl, CF 3 , CN, and NO 2 ; or R 17 and R 18 are taken together to form a monocyclic, saturated, partially unsaturated, or wholly unsaturated 5- to 7-membered ring optionally containing one to 4 heteroatoms independently selected from N, S and O; n is 1 or 2; wherein the acyl group is HC(O)— or a —C(O)R′″— group, wherein R′″ is selected from the group consisting of alkyl, substituted alkyl, and alkoxy; wherein the substituents for the substituted alkyl, aryl, or acyl consist of one or more substituents independently selected from the group consisting of halogen, CN, OH, NO 2 , amino, aryl, a heterocyclic ring consisting of a monocyclic, saturated, partially unsaturated, or wholly unsaturated 4- to 7-membered ring having 1 to 4 heteroatoms independently selected from N, S and O, alkoxy, aryloxy, alkylcarbonyl, alkylcarboxy, and arylthio; or a pharmaceutically acceptable salt thereof.