Patent ID: 7034048

Claim:
A compound of formula (I) wherein X and Y are independently selected from the group consisting of ═N—; —N(R 5 )—, wherein R 5 is selected from the group consisting of H, Me, Et, Pr, Bn, OH and —CH 2 COOR 6 , wherein R 6 represents H, Me, Et, Pr or Bn); ═CH; —O— and —S—; n is from 1 to 4; A is an optionally substituted 5-membered carbocyclic ring wherein 1 or 2 C atoms are replaced by an atom independently selected from the group consisting of N and O, A is fused with the aromatic group in formula (I) to form a fused bicycle, and (c) the ring containing X and Y is linked to a C atom of A; R 1 is H or C 1 to C 15 hydrocarbyl wherein up to three C atoms may optionally be replaced by an atom independently selected from the group consisting of N, O, and S, and up to three H atoms may optionally be replaced by halogen atoms; R 2 is selected from H, M; Et, Pr and OH, each R 3 being independently selected from H, Me, Et, Pr and OH when n is greater than 1; R 3 is selected from the group consisting of H, Me, Et and Pr when n is 1; or, when n is greater than 1, each R 3 is independently selected from the group consisting of H, Me, Et and Pr, or two R 3 groups on neighbouring carbon atoms are linked to form a C 3 to C 6 carbocyclic ring, or two R 3 groups are absent from neighbouring carbon atoms which are linked by a double bond; or R 2 and R 3 on the same carbon atom together represent an ═O group; R 4 is C 1 to C 15 hydrocarbyl wherein up to two C atoms may optionally be replaced by an atom independently selected from the group consisting of N, O, and S and up to three H atoms may optionally be replaced by halogen atoms; V is selected from the group consisting of —CO—NH—SO 2 —Ph, —SO 2 —NH—CO—Ph, —CH 2 OH, and a group of the formula —R 7 U, wherein U is selected from the group consisting of —COOH, tetrazolyl, —CONHOH— and —SO 3 H; and R 7 is selected from the group consisting of a bond; C 1 to C 6 hydrocarbylene, optionally substituted by hydroxy, amino or acetamido; —C—(C 1 to C 3 alkylene)-; —SO 2 NR 8 —CHR 9 —; —CO—NR 8 —CHR 9 —, wherein R 8 and R 9 are independently selected from H and methyl; and —NH—(CO) c —CH 2 —, c being 0 or 1; or a pharmaceutically acceptable salt thereof.