Patent ID: 7678802

Claim:
A compound of formula IA-ii: or a pharmaceutically acceptable salt thereof, wherein: a) the ring formed by R 1 and R 2 taken together is selected from: and the ring formed by R 1 and R 2 taken together, is optionally substituted at one or more substitutable carbon, nitrogen, or sulfur atoms with z independent occurrences of —R 4 , and z is 0-5; b) wherein z is 0-5, and R 4 groups, when present, are each independently halogen, CN, NO 2 , —N(R′) 2 , —CH 2 N(R′) 2 , —OR′, —CH 2 OR′, —SR′, —CH 2 SR′, —COOR′, —NRCOR′, —CON(R′) 2 , —OCON(R′) 2 , COR′, —NHCOOR′, —SO 2 R′, —SO 2 N(R′) 2 , or an optionally substituted group selected from C 1 -C 6 aliphatic, aryl, heteroaryl, cycloaliphatic, heterocycloaliphatic, arylC 1 -C 6 alkyl, heteroarylC 1 -C 6 alkyl, cycloaliphaticC 1 -C 6 alkyl, or heterocycloaliphaticC 1 -C 6 alkyl; c) wherein x is 1, and R 3 is an optionally substituted group selected from C 1 -C 6 aliphatic; d) wherein y is 0; and e) R 5a is —OH.