Patent ID: 7575569

Claim:
A system for delivering one or more agents to tissue surrounding a target vessel of a patient's body, the system comprising: an elongate delivery device comprising: a proximal tubular portion extending from a proximal end thereof to a distal end thereof over a length sufficient to reach a coronary sinus of the patient from a subclavian entry location, the distal end of the proximal tubular portion being tapered; a distal portion sized for introduction into the target vessel, the distal portion including an expandable sheath and a stiffening member, the expandable sheath including a proximal end, the proximal end of the sheath surrounding and overlying the distal end of the proximal tubular portion, being attached thereto, the expandable sheath extending from the proximal end thereof to a distal end thereof and the stiffening member including a proximal end, also being attached to the distal end of the proximal tubular portion, the stiffening member extending from the proximal end thereof to a distal end thereof and being attached to the expandable sheath, the distal end of the stiffening member being located distal to the distal end of the expandable sheath; and a lumen extending within the proximal tubular portion, between the proximal end of the tubular portion and the distal end of the tubular portion, and further extending distally, within the expandable sheath of the distal portion, to a distal opening of the lumen, which distal opening terminates the distal end of the expandable sheath; and a source of one or more agents coupled to the proximal end of the proximal tubular portion and communicating with the lumen in order to deliver the one or more agents through the lumen and out the distal opening thereof at a sufficient pressure to cause the one or more agents to extravasate through a wall of the target vessel, that is located downstream of the distal opening. and into surrounding tissue, when the distal portion of the device is introduced into the target vessel.