Patent ID: 8546583

Claim:
A compound according to formula (I), or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof, wherein R 1 is A-alkylene-; R 2 is hydrogen; R 3 is hydrogen or alkyl R 4 is phenyl, wherein the phenyl is unsubstituted or substituted with 1-5 substituents selected from the group consisting of alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkoxyalkyl, alkoxyalkyl, alkyl, alkylcarbonyl, alkylcarbonylalkyl, alkylcarbonyloxy, alkyl-S—, alkyl-S-alkyl, alkynyl, cyano, cyanoalkyl, formyl, formylalkyl, halogen, haloalkyl, hydroxy, hydroxyalkyl, —SH, N(O) 2 , and —NZ 1 Z 2 , wherein NZ 1 Z 2 means two groups Z 1 and Z 2 which are appended to the parent molecular moiety through a nitrogen atom, and wherein Z 1 and Z 2 are each independently hydrogen, alkyl, alkylcarbonyl, or formyl, or wherein Z 1 and Z 2 taken together with the nitrogen atom to which they are attached form a heterocyclic ring, optionally substituted with 1, 2, or 3 substituents selected from the group consisting of alkyl, hydroxy, and haloalkyl; A is a 4-, 5-, 6-, or 7-membered monocyclic heterocycle containing zero or one double bond, and one or two oxygen, and zero or one nitrogen as ring atoms wherein each A is independently unsubstituted or substituted with 1, 2, or 3 substituents independently selected from the group consisting of oxo, alkyl, —OH, and —O(alkyl); and L 1 is a single bond.