Patent ID: 7015243

Claim:
An ophthalmic solution comprising a therapeutically effective amount of a compound of formula I: or a pharmaceutically acceptable salt thereof, in admixture with a non-toxic, ophthalmically acceptable liquid vehicle, packaged in a container suitable for metered application wherein the wavy segment represents an α or β bond, a dashed line represents the presence or absence of a bond, R 1 is H, R 2 is OH, R 3 is H; W is O; R is selected from the group consisting of CO 2 R 4 , CONR 4 2 , CH 2 OR 4 , CONR 4 SO 2 R 4 , and P(O)(OR 4 ); R 4 is selected from the group consisting of H, phenyl and lower alkyl having from one to six carbon atoms; Y is a covalent bond or is selected from the group consisting of CH 2 , O, S and N; and Z is benzo[b]thiophen-3-yl or 3-chloro-benzo[b]thiophen-2-yl.