Patent ID: 7749991

Claim:
A therapeutic method for the treatment of fungal or bacterial pathological conditions, which comprises administering to a subject in a need of such a treatment a therapeutically effective amount of a pharmaceutical composition containing as active ingredient a compound of general formula (I) or a conjugate of a compound of general formula (I) with a macromolecule selected from the group consisting of aminoacids, polypeptides, proteins and polysaccharides, optionally in combination with pharmaceutically acceptable excipients, in which general formula (I): M is selected from the group consisting of Zn, Si(OR 8 ) 2 , Ge(OR 8 ) 2 and AlOR 8 ; R is H or a group selected from alkyl, alkenyl and alkyloxy group, linear or branched, having from 1 to 10 carbon atoms provided that, when R is different from H, the positions 8, 11, 15, 18, 22, 25 or 9, 10, 16, 17, 23, 24 are substituted; and R 1 and R 2 , equal or different from one another, are H or a group (X) p R 3 , wherein X is selected from the group consisting of O, S, —NR 6 and —CH 2 —; and R 3 is where: Y is selected from the group consisting of C1-C10 alkyl and phenyl, optionally substituted, or it forms with the Z group, to which it is bound, a saturated or unsaturated heterocycle, optionally substituted, which may contain up to two heteroatoms selected from the group consisting of N, O and S; Z is selected from the group consisting of —N, —CH 2 N and —CONHCH 2 CH 2 N; R 4 and R 5 , equal or different from one another, are selected from the group consisting of C1-C15 alkyl and phenyl, or form with the Z group, to which they are bound, a saturated or unsaturated heterocycle, optionally substituted, which may contain up to two heteroatoms selected from the group consisting of N, O and S; R 6 and R 7 , equal or different from one another, are selected from the group consisting of H and C1-C15 alkyl; m, n, p, w, t and u, independently from one another, are 0 or 1; and v is an integer between 1 and 3, provided that when R 1 and R 2 are the same, they are not H and are in the positions 1,4 or 2,3, whereas, when only one between R 1 and R 2 is different from H, the position 1 or 2 is substituted, or R 1 and R 2 , taken together, form a saturated or unsaturated heterocycle, possibly substituted, which may contain up to two heteroatoms selected from the group consisting of N, O and S; R 8 is selected from H and C1-C15 alkyl.