Patent ID: 7115576

Claim:
Water-soluble antibiotic derivative represented by structural formula (I): where: B=a polymer combined in a 1,4 linkage, selected from the group consisting of hydroxyethyl starch, hydroxypropyl starch, soluble amylose, soluble amylose in hydroxyethylated and/or hydroxypropylated form, soluble amylopectin, and soluble amylopectin in hydroxyethylated and/or hydroxypropylated form, R 3 , R 4 are independently H, —(CH 2 ) 2 —OH or with the conditions that B=amylose or amylopectin, if R 2 ═R 3 ═R 4 ═H B=hydroxyethyl starch, hydroxyethylated amylopectin or hydroxyethylated amylose, if R 2 , R 3 , or R 4 ═(CH 2 ) 2 —OH, B=hydroxypropyl starch, hydroxypropylated amylopectin or hydroxypropylated amylase, if R 2 , R 3 , or A is with R 1 ═H or OH or and with the condition that if then and if then A is with R 1 ═H or OH, wherein the group represented by the following structural formula is combined with the amino group at C 3 of the amino sugar of the antibiotic with the formation of a peptide bond.