Patent ID: 7517992

Claim:
A compound of the formula Y: where; R 1 is O, S; R 2 is pyrid-2-yl, substituted at the 5 position with the —(CHR 11 ) p -E-(CHR 11 ) q —R 10 moiety; R 3 is H; R 4 and R 7 are fluoro; R 5 and R 6 are H; X is —(CR 8 R 8 ′) n -D-(CR 8 R 8 ′) m —; D is O; m is 1; n is 0; R 8 and R 8 ′ are H; E is —O; p and q are 0; R 10 is pyrid-3yl, optionally substituted with halo or cyano; and pharmaceutically acceptable salts and prodrugs thereof.