Patent ID: 7626386

Claim:
A nuclear magnetic resonance (NMR) method for singlet-state exchange NMR-spectroscopy, the method comprising the steps of: a) exciting single-quantum in-phase coherences; b) generating single-quantum anti-phase coherences; c) exciting zero-quantum coherences ZQ x and/or longitudinal two-spin order 2I z S z (=“ZZ order”) using a π/4 pulse; d) reversing a sign of the zero-quantum coherences ZQ x under an effect of a difference of chemical shifts of examined spins; e) transforming the zero-quantum coherences ZQ x and/or longitudinal two-spin ZZ order into singlet-state populations by means of RF irradiation during a mixing period τ m ; f) reconverting the singlet-state populations remaining at an end of the mixing period τ m into zero-quantum coherences ZQ x and/or ZZ order; g) reversing a sign of the zero-quantum coherences ZQ x under an effect of a difference of chemical shifts of examined spins; and h) reconverting zero-quantum coherences ZQ x and/or ZZ order into single-quantum anti-phase coherences.