Patent ID: 8535537

Claim:
A microdialysis device for analyzing a fluidic sample, the microdialysis device comprising: a permeable membrane; wherein the permeable membrane has a first surface to be brought in contact with the fluidic sample to traverse the permeable membrane; wherein the permeable membrane has a second surface to be brought in contact with a dialysis fluid; wherein the first surface is smoother than the second surface so that a surface roughness of the first surface is smaller than a surface roughness of the second surface; wherein the permeable membrane comprises pores having a mean size which increases from the first surface towards the second surface; wherein the permeable membrane comprises a hollow tube an outer surface of the hollow tube forming the first surface; wherein the pores have a size at the first surface smaller than essentially 0.1 μm; wherein the pores have a size at the second surface in the range between essentially 0.1 μm and essentially 0.4 μm; and wherein the permeable membrane has a molecular cut-off in a range between 1 kDa and 100 kDa.