Patent ID: 7163939

Claim:
A compound of formula (I) or a therapeutically acceptable salt thereof, wherein is a single or double bond; A is aryl, wherein the aryl is optionally substituted with one, two, or three substituents independently selected from the group consisting of alkoxy, alkoxyalkoxy, alkoxyalkoxyalkoxy, alkyl, cyano, halo, haloalkylsulfonyloxy, haloalkoxy, heteroarylalkoxy, heterocycle, heterocyclealkoxy, heterocycleoxyalkoxy, heterocycleoxyalkyl, heterocycleoxyalkynyl, heteroarylcarbonylalkoxy, haloalkyl, hydroxyalkenyl, hydroxyalkoxy, hydroxyalkyl, hydroxyalkynyl, hydroxy, nitro, NR a R b , (NR a R b )alkoxy, (NR a R b )alkyl, and (NR a R b )alkynyl; R 1 is selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl, carboxy, cyano, halo, and nitro; R 2 and R 3 are independently selected from the group consisting of hydrogen, alkoxy, alkoxycarbonyl, alkyl, alkylsulfonyl, arylsulfonyl, halo, hydroxy, and NR a R b ; or R 2 and R 3 , together with the atoms to which they are attached, form an epoxide; X is N; Y is selected from the group consisting of CH 2 , O, and NR z , wherein R z is selected from the group consisting of hydrogen and alkyl; Z is O; L 1 and L 2 are independently selected from the group consisting of a bond and alkylene; R a and R b are independently selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl, alkylcarbonyl, alkylsulfonyl, aryl, arylalkyl, arylsulfonyl, haloalkylcarbonyl, haloalkylsulfonyl, heteroaryl, heteroarylalkyl, heteroarylcarbonyl, heteroarylsulfonyl, and (NR c R d )alkylcarbonyl; and R c and R d are independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl.