Patent ID: 8513423

Claim:
A compound of Formula (I) wherein Y and Z are independently selected from Group a) or Group b) such that one of Y and Z is Group a) and the other is Group b); Group a) is i) C 6-10 aryl is unsubstituted or substituted with a substituent selected from the group consisting of fluoro, chloro, C 1-4 alkyl, C 1-4 alkoxy, cyano, and trifluoromethyl; or ii) an unsubstituted heteroaryl selected from the group consisting of thiazolyl, isothiazolyl, and 1H-pyrrolyl; Group b) is selected from the group consisting of i) C 6-10 aryl; ii) a heteroaryl selected from the group consisting of benzoxazolyl, benzothiazolyl, benzimidazolyl, benzothienyl, indazolyl, and indolyl; iii) phenylmethyl-phenyl wherein the phenyl group of phenylmethyl is unsubstituted or substituted with trifluoromethyl or fluoro; and iv) 1,3-dihydro-3H-benzimidazol-2-on-yl; wherein Group b) other than phenylmethyl-phenyl is unsubstituted or substituted with one or two substitutents independently selected from the group consisting of bromo, chloro, fluoro, iodo, C 1-4 alkyl, C 1-4 alkoxy, and R b ; provided that no more than one substituent is R b ; and R b is selected from the group consisting of trifluoromethyl, 2,2,2-trifluoroethyl, 3,3,3-trifluoropropyl, 4,4-difluorocyclohexyl, thienyl, pyridinyl, and phenyl; wherein said thienyl, pyridinyl, and phenyl of R b are unsubstituted or substituted with one or two substituents independently selected from the group consisting of trifluoromethyl, methyl, chloro, cyano, and fluoro; R is hydrogen or hydroxy; and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof.