Patent ID: 7381402

Claim:
An aerosol formulation, which comprises 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl-2(1H)-quinolinone or a salt thereof, a liquefied HFA propellant, a co-solvent selected from pharmaceutically acceptable alcohols, and phosphoric acid, wherein said formulation is in the form of a solution, and said phosphoric acid is present in an amount equivalent to 0.0004 to 0.040% by weight of 15 M phosphoric acid, based on the total weight of the formulation, and wherein said 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone or salt thereof is present in an amount of 0.0005% to 0.0032% w/v, based on the total volume of the formulation.