Patent ID: 8247424

Claim:
A compound according to the general formula Ia or Ib: wherein in each R1 means H, R3 means H, F, Cl, Br, or I and R2 means (CH 2 ) r CH═N—NHCO—R23, (CH 2 ) r CH═N—NHC(O)NH—R23, (CH 2 ) r CH═N—NHC(S)NH—R23, (CH 2 ) r CH═N—NHC(NH)NH—R23, (CH 2 ) r CH═N—NHC(NH)—R23, (CH 2 ) r CH═N—NHCO—CH 2 NHCOR21, (CH 2 ) r CH═N—NHCS—R23, (CH 2 ) r CH═N—NR21R22, (CH 2 ) r CH═N—N—(C 3 NX′R211R212R213R214), —(CH 2 ) r CH═N—NHSO 2 aryl, or —(CH 2 ) r CH═N—NHSO 2 heteroaryl, with r=0, 1, 2, 3, 4, 5, wherein X′═NR215, O, or S, and R211, R212, R213, R214, and R215 are independently H or C 1 -C 6 alkyl, R21, R22 are independently H, C 1 -C 14 alkyl, C 1 -C 14 alkanoyl, C 1 -C 6 alkylhydroxy, C 1 -C 6 alkoxy, C 1 -C 6 alkylamino, C 1 -C 6 alkylamino-C 1 -C 6 alkyl, C 1 -C 6 alkylamino-di-C 1 -C 6 -alkyl, cycloalkyl, C 1 -C 4 alkylcycloalkyl, heterocycloalkyl, C 1 -C 4 alkylheterocycloalkyl, aryl, aryloyl, C 1 -C 4 alkylaryl, heteroaryl, heteroaryloyl, C 1 -C 4 alkylheteroaryl, cycloalkanoyl, C 1 -C 4 alkanoylcycloalkyl, heterocycloalkanoyl, C 1 -C 4 alkanoylheterocycloalkyl, C 1 -C 4 alkanoylaryl, C 1 -C 4 alkanoylheteroaryl, or R21 and R22, together with the N, form a ring with 4, 5, 6, 7, or 8 members, which may optionally contain still another heteroatom selected from the group N, O, and S, R23 independently of R21, has the same meanings as R21, or CH 2 -pyridinium salts, CH 2 -tri-C 1 -C 6 alkylammonium salts, CONH 2 , CSNH 2 , CN, or CH 2 CN, R24 independently of R21, has the same meanings as R21, or H, CN, COCH 3 , COOH, COOR21, CONR21R22, NH 2 , or NHCOR21, R25 independently of R21, has the same meanings as R21, or H, CN, COCH 3 , COOH, COOR21, CONR21R22, NH 2 , or NHCOR21, R24, R25 together with the N, form a ring with 4, 5, 6, 7, or 8 members, which may optionally contain still another heteroatom selected from the group N, O, and S, R31, R32 are independently C 1 -C 6 alkyl, or R31 and R32, together with the N, form a ring with 4, 5, 6, 7, or 8 members, which may optionally contain still another heteroatom selected from the group N, O, and S, R5 means C 1 -C 20 alkyl, R4, R6, R7 independently mean H, R41 independently from R21, has the same meanings as R21, X means O, Y means O, S, NR9, wherein R9 may be H or C 1 -C 6 alkyl, as well their stereoisomers, tautomers, and their physiologically tolerable salts, wherein heterocycloalkyl by itself or as part of another substituent means a group selected from the group consisting of pyrrolidine, piperidine, morpholine, wherein Y″ means CH 2 , S, O, NH, or NC 1 -C 6 alkyl, and wherein heteroaryl by itself or as part of another substituent means a ring system selected from the group consisting of