Patent ID: 7838518

Claim:
A 1-arylsulfonyl-3-substituted indole or indoline compound having the general formula I wherein Ar is selected from phenyl, biphenyl, naphthyl, thienyl, furyl, benzothienyl, benzothiadiazolyl, 2,3-dihydrobenzofuranyl, 2,3-dihydrobenzodioxinyl, quinolinyl, and isoquinolinyl, Ar being optionally substituted with 1-5 substitutents selected from halogen, (C 1-4 )alkyl (optionally substituted with halogen), (C 1-4 )alkyloxy (optionally substituted with halogen), (C 6-12 )aryl (optionally substituted with halogen or (C 1-4 )alkyloxy), (C 6-12 )aryloxy (optionally substituted with halogen), di(C 1-4 )alkylamino, (C 1-4 )alkanoyl or (C 1-4 )alkanoylamino; the dotted line represents an optional bond; n is 0 or 1; m is 2-3; R 6 represents 1-4 substituents independently selected from H, (C 1-4 )alkyl (optionally substituted with halogen), (C 1-4 )alkyloxy (optionally substituted with halogen), (C 1-4 )alkyloxycarbonyl, cyano, nitro and halogen; R 7 together with R 9 complete a 7-membered saturated ring; each R 8 is independently H, (C 1-4 ) alkyl or (C 6-12 )aryl (optionally substituted with halogen, (C 1-4 )alkyl or (C 1-4 )alkyloxy); and R 10 is H, (C 1-4 )alkyl, (C 6-12 )aryl or (C 6-12 )aryl(C 1-4 )alkyl; each R 11 is independently H or (C 1-4 )alkyl; or a pharmaceutically acceptable salt thereof.