Patent ID: 8906930

Claim:
A compound of formula I in which R 1 , R 2 each, independently of one another, denote H, A, (CH 2 ) n Het or (CH 2 ) n Ar, R 1 and R 2 , together with the N atom to which they are bonded, also denote a saturated, unsaturated or aromatic mono- or bicyclic heterocycle, which may contain a further 1 to 3 N, O and/or S atoms and which is unsubstituted or mono-, di- or trisubstituted by Hal, A, (CH 2 ) n Het, (CH 2 ) n Ar, (CH 2 ) n OH, (CH 2 ) n OA, (CH 2 ) n NH 2 , (CH 2 ) n COOH, (CH 2 ) n COOA, NHCOA, NA′COA, CONH 2 , CONHA, CONAA′, OC(═O)(CH 2 ) p NH 2 and/or ═O (carbonyl oxygen), R 3 and R 4 , together with the C atom to which they are bonded, denote a saturated or unsaturated monocyclic C3-C10-carbocycle, which may contain a further 1 to 3 N, O and/or S atoms and which is unsubstituted or mono-, di- or trisubstituted by Hal, A, (CH 2 ) n OH, (CH 2 ) n OA, (CH 2 ) n NH 2 , (CH 2 ) n COOH, (CH 2 ) n COOA, NHCOA, NA′COA, CONH 2 , CONHA, CONAA′, OC(═O)(CH 2 ) p NH 2 and/or ═O (carbonyl oxygen), X denotes NR 5 R 6 , CONR 5 R 6 , CH 2 NR 5 R 6 , COOR 5 , —OR 5 , CH 2 OR 5 , COHet, Het, CONH(CH 2 ) p CN or CONH(CH 2 ) p NR 5 R 6 , R 5 , R 6 each, independently of one another, denote H, A, (CH 2 ) n Het or (CH 2 ) n Ar, Ar denotes phenyl, naphthyl, tetrahydronaphthyl or biphenyl, each of which is unsubstituted or mono-, di-, tri-, tetra- or pentasubstituted by A, Hal, (CH 2 ) n OA, (CH 2 ) n OH, (CH 2 ) n CN, SA, SOA, SO 2 A, NO 2 , C≡CH, (CH 2 ) n COOH, CHO, (CH 2 ) n COOA, CONH 2 , CONHA, CONAA′, NHCOA, CH(OH)A, (CH 2 ) n NH 2 , (CH 2 ) n NHA, (CH 2 ) n NAA′, (CH 2 ) n NHSO 2 A, SO 2 NH(CH 2 ) n NH 2 , SO 2 NH 2 , SO 2 NHA, SO 2 NAA′, CONH(CH 2 ) n COOA, CONH(CH 2 ) n COOH, NHCO(CH 2 ) n COOA, NHCO(CH 2 ) n COOH, CONH(CH 2 ) n NH 2 , CONH(CH 2 ) n NHA, CONH(CH 2 ) n NAA′, CONH(CH 2 ) n CN and/or (CH 2 ) n CH(NH 2 )COOH, Het denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono-, di- or trisubstituted by A, OA, OH, phenyl, SH, S(O) m A, Hal, NO 2 , CN, COA, COOA, COObenzyl, CONH 2 , CONHA, CONAA′, SO 2 NH 2 , NH 2 , NHA, NAA′, NHCOA, NHSO 2 A and/or ═O (carbonyl oxygen), A, A′ each, independently of one another, denote unbranched or branched alkyl having 1-10 C atoms, in which 1-3 non-adjacent CH 2 groups may be replaced by O, S, SO, SO 2 , NH, NMe or Net, and/or, in addition, 1-5 H atoms may be replaced by F and/or Cl, or cyclic alkyl having 3-8 C atoms, Hal denotes F, Cl, Br or I, n denotes 0, 1, 2, 3 or 4, p denotes 1, 2, 3 or 4, or pharmaceutically usable salts, tautomers or stereoisomers thereof, including mixtures thereof in all ratios.