Patent ID: 8148389

Claim:
A method of promoting proliferation of a corneal epithelial cell, comprising administering an effective amount of a PPARα or δ agonist to a subject in need of promotion of proliferation of a corneal epithelial cell, wherein the PPARα or δ agonist is a compound represented by the formula (I): wherein A is a hydrogen atom or an alkyl group having a carbon number of 1 to 6, B is a linker selected from the group consisting of —CO—, —NH—, —(CH 2 ) n —S—, —(CH 2 ) n —O— and —O— (CH 2 ) n —O— wherein n is an integer of 1 to 3, X and Y are the same or different, and each is a carbon atom or a nitrogen atom, Z is an oxygen atom, a sulfur atom or —CH 2 —, Ar 1 is a 5- to 6-membered aromatic cyclic group optionally having 1 to 3 substituents, R 1 and R 2 are the same or different and each is a hydrogen atom or an alkyl group having a carbon number of 1 to 6, and R 3 is hydrogen, a halogen atom or an alkyl group having a carbon number of 1 to 6, or ((4-chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)acetic acid, or a pharmacologically acceptable salt thereof.