Patent ID: 8580498

Claim:
A method of predicting tumor recurrence in a post-operative patient, the patient having had surgery that removed an entire tumor, comprising: obtaining a tissue sample of the tumor removed from the post-operative patient, the patient having had surgery that removed the entire tumor; determining a recurrence value, wherein the recurrence value is an expression value of Excision Repair Cross-Complementing 1 (ERCC1) in a predetermined sample; determining the level of ERCC1 in the sample; comparing the level of ERCC1 in the sample to the recurrence value; wherein an ERCC1 level in the sample below the recurrence value is indicative of recurrence of the tumor; and wherein an ERCC1 level in the sample greater than the recurrence value is indicative of non-recurrence of the tumor; and, if the ERCC1 level in the sample is below the recurrence value, prescribing an adjuvant therapy regimen for the post-operative patient or treating the post-operative patient whose ERCC1 level is below the recurrence value with an adjuvant therapy regimen; and if the ERCC1 level in the sample is above the recurrence value not prescribing or treating the post-operative patient with an adjuvant therapy regimen.