Patent ID: 8119674

Claim:
A 4-phenylimidazole-2-thione tyrosinase inhibiting compound having the formula (I): in which: a) when R2=H, then R1 is: a C 2 -C 7 alkyl radical, with the proviso that R1 cannot be isopropyl, n-propyl or tert-butyl, a hydroxymethyl, trifluoromethoxy or difluoromethoxy radical, a C 3 -C 7 cycloalkyl radical, with the proviso that one of the carbon atoms of the ring may optionally be replaced by an oxygen or sulfur atom, a C 4 -C 9 cycloalkylalkyl radical, a morpholinyl, thiomorpholinyl, piperazinyl or N-methylpiperazinyl group, a carboxyl substituent, a (C 1 -C 4 alkoxy)carbonyl group, or a C 2 -C 6 alkoxy radical, with the proviso that R1 cannot be n-butoxy; b) when R1=H, then R2 is: a C 1 -C 7 alkyl radical, a trifluoromethoxy, difluoromethoxy or cyano radical, a C 3 -C 7 cycloalkyl radical, with the proviso that one of the carbon atoms of the ring may optionally be replaced by an oxygen or sulfur atom, a C 4 -C 9 cycloalkylalkyl radical, a (C 1 -C 4 alkoxy)carbonyl radical, a C 1 -C 6 alkoxy radical, with the proviso that R2 cannot be n-propoxy; c) and, when R2 is in the ortho position with respect to R1, then R1 and R2, which may be identical or different, are each a C 1 -C 5 alkyl radical or together form a 5- or 6-sided hydrocarbon ring, in which 1 or 2 carbon atom(s) are optionally replaced by 1 or 2 oxygen atom(s), or a salt or tautomeric form thereof.