Patent ID: 7125906

Claim:
A compound of Formula (VIId), wherein R 1 is independently selected from hydroxy, amino, alkanoylamino, —OPO 3 H 2 , or C 1-4 alkoxy, wherein the amino group is optionally substituted with an amino acid residue and the hydroxy group is optionally esterified; X is selected from —O—, —S—, —SO—, or —SO 2 —; R 2 is selected from hydrogen, C 1-4 alkyl, C 1-4 alkoxy; R 4 is independently selected from hydrogen, C 1-4 alkyl, 1-4 alkanoyl, C 1-4 alkoxycarbonyl, C 1-4 alkoxycarbonylC 1-4 alkyl, aminoC 1-4 alkyl, carbamoyl, carbamoylC 1-4 alkyl, cyano, cyanoC 1-4 alkyl, hydroxy or hydroxyC 1-4 alkyl; R 5 is selected from hydrogen, C 1-4 alkyl, or a group of Formula (III) wherein Y is selected from —NH—, —O—, or a bond; Z is selected from —NH—, —O—, —C(O)— or a bond; r is an integer from 0 to 4; t is an integer from 0 to 1; R 8 is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, aryl, 5- or 6-membered heterocyclyl, 5- or 6-membered heteroaryl, wherein aryl, heteroaryl or heterocyclyl are optionally substituted with C 1-4 alkyl, C 1-4 alkoxy, or a group of Formula (IV) wherein n is an integer from 1 to 6, and; R 9 and R 10 are independently selected from hydrogen, C 1-4 alkyl or aryl; p is an integer from 0 to 1 and q is an integer from 1 to 3; or a salt, or solvate thereof.