Patent ID: 8536186

Claim:
At least one chemical entity chosen from compounds of Formula I and pharmaceutically acceptable salts thereof wherein: X and Y are N; R 1 is phenyl optionally substituted with one, two, or three groups chosen from halo, optionally substituted lower alkyl, lower alkoxy, and hydroxy; L is chosen from —C(O)O—, N(R 3 )C(O)—, and —S(O) 2 N(R 3 )—; R 2 is hydrogen; R 3 is chosen from hydrogen and lower alkyl; R 4 is hydrogen; and R 5 is chosen from hydrogen and fluoro, provided that the compound of Formula I is not 6-(4-methoxy-phenyl)-pyrimidine-4-carboxylic acid; 6-(3,4-Dichloro-phenyl)-2-methyl-pyrimidine-4-carboxylic acid; or 6-phenylpyrimidine-4-carboxylic acid.