Patent ID: 8093245

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: Q is C or N; X is a bond, NR 5 , N(C(O)R 5 ), N(C(O)OR 5 ), O, S, SO 2 , C, CH, or CH 2 ; Y is a bond, C(O), C(O)NH, C(O)NH 2 CH 2 , SO 2 , NR 5 , N(C(O)R 5 ), N(C(O)OR 5 ), or CH 2 , with the proviso that Y is not a bond if X is a bond; or X and Y are taken together to provide one bond between Z 1 and Q; Z 1 is optionally substituted cycloalkyl, aryl, or heterocycle; R 1 is hydrogen, halogen, —OH, —NH 2 , —NO 2 , —CN, or optionally substituted alkyl; R 2 is hydrogen, halogen, or optionally substituted alkyl; R 3 is hydrogen, halogen, —OR 6 or —NR 7 R 8 ; R 4 is hydrogen, —C(O)(CH 2 ) n R 9 , —C(O)NH(CH 2 ) n R 9 , —NHC(O)(CH 2 ) n R 9 , or optionally substituted alkyl, aryl, heterocycle, alkyl-aryl, or alkyl-heterocycle; R 5 is hydrogen or optionally substituted alkyl, aryl, heterocycle, alkyl-aryl or alkyl-heterocycle; R 6 is hydrogen or optionally substituted alkyl, aryl, heterocycle, alkyl-aryl or alkyl-heterocycle; R 7 and R 8 are each independently hydrogen, or optionally substituted alkyl, aryl, heterocycle, alkyl-aryl or alkyl-heterocycle, or taken together with the nitrogen atom to which they are attached, form an optionally substituted heterocycle; R 9 is optionally substituted alkyl, aryl or heterocycle; and n is 0-3.