Patent ID: 7973035

Claim:
A compound of Formula I: wherein: wherein R 4 ═H, F, Cl, Br, I, OH, OCH 3 , OCH 2 CH 3 , —C (1-3 ) alkyl, —CO 2 R 5 , CONR 6 R 7 , C≡CR 8 , or CN; wherein R 5 ═H, or —C (1-3) alkyl; R 6 ═H, or —C (1-3) alkyl; R 7 ═H, or —C (1-3) alkyl; and R 8 ═H, —CH 2 OH, or —CH 2 CH 2 OH; R 2 is cycloalkyl, spiro-substituted cycloalkenyl, heterocyclyl, spiro-substituted piperidinyl, thiophenyl, dihydrosulfonopyranyl, phenyl, furanyl, tetrahydropyridyl, or dihydropyranyl, any of which may be independently substituted with one or two of each of the following: chloro, fluoro, hydroxy C (1-3) alkyl, and C (1-4) alkyl; X is selected from the group consisting of: wherein R 1 and R 10 are independently H, —CH 3 , or —C 2 -C 5 alkyl, optionally substituted with one or two of: Me, Et, OH, NH 2 , NHMe, NMe 2 , NHEt, Net 2 , pyrrolidinyl, pyridyl, morpholino, CONH 2 , or COOH and such that when any two heteroatoms are attached to said C 2 to C 5 alkyl group there exists at least two carbon atoms between them, and Z is H, F, Cl, Br, C 1 -C 3 alkyl or —CH 2 OH; and J is CH or N; or a tautomer or pharmaceutically acceptable salt thereof.