Patent ID: 8497307

Claim:
A compound represented by Formula (I): including salts, esters, and prodrugs thereof, wherein, R 1 is X 1 is —N(R 2 )—, O, or —C(R 6 ) 2 —; X 2 is —N(H)—, —N(alkyl)-, —N(hydroxyalkyl)-, O, S, or —C(R 6 ) 2 —; X 3 is —N(R 2 )—, —C(R 6 ) 2 —, or —C(R 6 ) 2 C(R 6 ) 2 —; R 2 and R 3 represent independently for each occurrence hydrogen or (C 1 -C 4 )alkyl; R 4 is R 5 represents independently for each occurrence hydrogen, halogen, alkyl, haloalkyl, —NO 2 , or —CN; R 6 represents independently for each occurrence hydrogen or alkyl; R 7 represents independently for each occurrence halogen, alkyl, haloalkyl, or alkoxy; R 8 represents independently for each occurrence hydrogen, halogen, alkyl, haloalkyl, or alkoxy; n is 0, 1, 2, 3, or 4; m represents independently for each occurrence 1 or 2; and the stereochemical configuration at a stereocenter in a compound represented by Formula (I) is R, S, or a mixture thereof.