Patent ID: 8394818

Claim:
A compound of formula I: wherein: R 1 is an optionally substituted group selected from the group consisting of 6-10-membered aryl; C 7-15 arylalkyl; C 6-15 heteroarylalkyl; C 1-12 heteroaliphatic; C 1-12 aliphatic; 5-10-membered heteroaryl having 1-4 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; and 4-7-membered heterocyclic having 1-2 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; each occurrence of R 2 is independently halogen, —NR 2 —OR, —SR, or an optionally substituted group selected from the group consisting of C 1-12 acyl; 6-10-membered aryl; C 7-15 arylalkyl; C 6-15 heteroarylalkyl; C 1-12 heteroaliphatic; C 1-12 aliphatic; 5-10-membered heteroaryl having 1-4 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; and 4-7-membered heterocyclic having 1-2 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; j is an integer from 1 to 4, inclusive; R 3 and R 4 are independently hydrogen, hydroxyl, alkoxy, halogen, or optionally substituted C 1-6 aliphatic, with the proviso that R 3 and R 4 are not taken together to form a ring; and each R is independently hydrogen, an optionally substituted group selected from the group consisting of C 1-12 acyl; 6-10-membered aryl; C 7-15 arylalkyl; C 6-15 heteroarylalkyl; C 1-12 aliphatic; 5-10-membered heteroaryl having 1-4 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; 4-7-membered heterocyclic having 1-2 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; and C 1-12 heteroaliphatic having 1-2 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; or: two R on the same nitrogen atom are taken with the nitrogen to form a 4-7-membered heterocyclic ring having 1-2 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur.