Patent ID: 6916847

Claim:
A compound of having the Formula: or a pharmaceutically acceptable salt thereof, wherein; B is isopropyl; A is a bond; X 0 is selected from the group consisting of hydrido, alkyl, cyano, halo, haloalkyl, haloalkoxy, haloalkylthio, amino, aminoalkyl, alkylamino, amidino, hydroxy, hydroxyamino, alkoxy, hydroxyalkyl, alkoxyamino, thiol, and alkylthio; R 2 is optionally substituted 3-amino-5-carboxyphenyl Y 0 is the formula wherein J 5 , J 6 , D 5 , D 6 and the ring carbon atoms to which they are attached define a phenyl or 5- or 6-membered heteroaryl ring, T, wherein one of J 5 and J 6 is absent when T is a 5-membered heteroaryl ring, J 5 is optionally substituted by R 17 when J 5 is a carbon atom, J 6 is optionally substituted by R 18 when J 6 is a carbon atom, D 5 is optionally substituted by R 16 when D 5 is a carbon atom and D 6 is optionally substituted by R 19 when D 6 is a carbon atom; R 16 , R 17 , R 18 , and R 19 are independently selected from the group consisting of hydrido, amidino, guanidino, carboxy, haloalkylthio, alkoxy, hydroxy, amino, alkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, alkanoyl, haloalkanoyl, alkyl, halo, haloalkyl, haloalkoxy, hydroxyalkyl, aminoalkyl, and cyano; Q b is selected from the group consisting of NR 20 R 21 , hydrido, N(R 26 )C(NR 25 )N(R 23 )(R 24 ), and C(NR 25 )NR 23 R 24 ; R 20 , R 21 , R 23 , R 24 , R 25 , and R 26 are independently hydrido or alkyl; and Q s is CH 2 .