Patent ID: 8071617

Claim:
A compound of the following structure: or pharmaceutically acceptable salts thereof; wherein â€”C(â•O)NHC(R 1 )(R 2 )R 3 is a moiety having the following structure: R 3A is hydrogen; R S is hydrogen; Ar 2 is: s is an integer of 1; each occurrence of R P1 is independently hydrogen, halogen, or -GR G1 , wherein G is â€”SO 2 â€”, or â€”SO 2 NR G2 â€”; and R G1 and R G2 are independently hydrogen, an aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic or heteroaromatic moiety; R B1 , R B2 and R E are hydrogen; R 4A and R 4B are each Cl; L is Câ•O; and AR 1 is wherein R Q1 is independently hydrogen, OR Q3 , OCF 3 , SR Q3 , halogen, CN, isocyanate, NO 2 , CF 3 , NR Q3 R Q4 , â€”SO 2 R Q3 , alkyl-NR Q3 R Q4 , alkyl-C(â•O)â€”NR Q3 R Q4 , alkyl-C(â•O)R Q3 , or an aliphatic, alicyclic, heteroaliphatic, heterocyclic, aryl, heteroaryl, alkylaryl, alkylheteroaryl, heteroalkylaryl, or heteroalkylheteroaryl moiety, wherein each occurrence of R Q3 and R Q4 is independently hydrogen, a protecting group, or an aliphatic, heteroaliphatic, aryl or heteroaryl moiety; and r is an integer from 0-6.