Patent ID: 8871747

Claim:
A compound of the formula (I) wherein X is selected from ═O and ═S; A is selected from —C(═O)— and —S(═O) 2 —; B is selected from —(CH 2 ) 3-6 —, —O—, and —O—(CH 2 ) 2-5 —; D is selected from a single bond —O—, and —NR 9 , wherein R 9 is selected from hydrogen, optionally substituted C 1-12 -alkyl, optionally substituted C 1-12 -alkenyl, optionally substituted aryl, optionally substituted heterocyclyl, and optionally substituted heteroaryl; m is an integer of 2-8 and n is 0; p is an integer of 0-2; R 1 is selected from optionally substituted heteroaryl; R 2 is selected from hydrogen, optionally substituted C 3-12 -cycloalkyl, —[CH 2 CH 2 O] 1-10 -(optionally substituted C 1-6 -alkyl), CH 2 ) 0-2 -(optionally substituted aryl), —(CH 2 ) 0-2 -(optionally substituted heteroaryl) and —(CH 2 ) 0-2 -(optionally substituted heterocyclyl); and R 3 is selected from optionally substituted C 3-12 -cycloalkyl, —[CH 2 CH 2 O] 1-10 -(optionally substituted C 1-6 -alkyl), optionally substituted C 1-12 -alkenyl, optionally substituted aryl, optionally substituted heterocyclyl, and optionally substituted heteroaryl; R 4 is independently selected from hydrogen, optionally substituted C 3-12 -cycloalkyl, —(CH 2 ) 0-2 -(optionally substituted aryl), —(CH 2 ) 0-2 -(optionally substituted heteroaryl) and —(CH 2 ) 0-2 -(optionally substituted heterocyclyl); and R 4* is hydrogen; with the provisos that R 1 is not optionally substituted thiazol-2-yl when p is 0; and with the proviso that the compound is not phenyl-NH—C(═O)—(CH 2 ) 5 —NH—C(═S)—NH-(4-pyridyl); and pharmaceutically acceptable salts thereof, and prodrugs thereof.