Patent ID: 7585977

Claim:
A compound of formula I: or pharmaceutical acid addition salt thereof; wherein: m, q and r are independently 0, 1 or 2; n is 0 or 1; R is H or COR 2 ; R 0 is independently at each occurrence OH, CF 3 , halo, C 1 -C 6 alkyl or C 1 -C 6 alkoxy; R 1 and R 1′ are independently C 1 -C 6 alkyl, C 1 -C 6 alkoxy, NR 3 R 3a , CF 3 or CH 2 CF 3 ; or when n and q are 0, the —SO 2 R 1 moiety may combine with the phenyl ring to which it is attached to form a moiety of formula (a) or (b): wherein t and v are 0, 1 or 2 provided that the sum of t+v must be 2; R 2 is C 1 -C 6 alkyl; C 1 -C 6 alkoxy; NR 4 R 4 ; phenoxy; or phenyl optionally substituted with halo; R 3 is C 1 -C 6 alkyl or phenyl; R 3a and R 4 are independently at each occurrence H, C 1 -C 6 alkyl, or phenyl; X is O, CH 2 or CO; X 1 is O or NR 5 ; R 5 is H or C 1 -C 6 alkyl; R 8 is H or methyl provided that if r is 1 or 2, then R 8 must be H and that if r is 0, then R 8 must be methyl; and Y is S, CH 2 CH 2 or CH═CH; provided that the Compound of Formula I is not,