Patent ID: 7300951

Claim:
A compound of Formula (I), or pharmaceutically acceptable salt thereof, wherein Formula (I) has the structure: wherein: T is selected from the group consisting of CHO, COR 8 , and C(OH)R 1 R 2 ; R 1 and R2 are independently selected from the group consisting of hydrogen, lower alkyl, substituted lower alkyl, CF 3 , alkenyl, substituted alkenyl, alkynyl, and substituted alkynyl; R 3 is selected from the group consisting of hydrogen, lower alkyl and substituted lower alkyl; R 4 is selected from the group consisting of(CF 3 ) n alkyl, (CF 3 ) n (substitutedalkyl), (CF 3 ) n alkylphenyl, (CF 3 ) n alkyl(substitutedphenyl), and (F) n cycloalkyl; n=1 –3; R 5 is selected from the group consisting of hydrogen, halogen, CF 3 , diene fused to Y when Y═C, and substituted diene fused to Y when Y═C; W, Y and Z are independently selected from the group consisting of C, CR 6 and N with the proviso that at least one of W or Y or Z must be C; R 6 is selected from the group consisting of hydrogen, halogen, lower alkyl, and substituted lower alkyl; X is selected from the group consisting of O, S, SO 2 , and NR 7 ; R 7 is selected from the group consisting of hydrogen, lower alkyl, substituted lower alkyl, benzyl, substituted benzyl, phenyl, and substituted phenyl; and R 8 is selected from the group consisting of lower alkyl, CF 3 , phenyl, and substituted phenyl; or a pharmaceutically acceptable salt, hydrate, or prodrug thereof.