Patent ID: 6949542

Claim:
A compound of formula I wherein X is a single bond or an ethynediyl group; and wherein in case X is a single bond, R 1 is hydrogen, cyano, halogen, lower alkyl, lower alkoxy, fluoro-lower alkyl, fluoro-lower alkoxy, pyrrol-1-yl, or phenyl, which is unsubstituted or substituted by one or two substituents selected from the group consisting of halogen, lower alkyl or fluoro-lower alkyl; or in case X is an ethynediyl group, R 1 is phenyl, which is unsubstituted or substituted by one or two substituents selected from the group consisting of halogen, lower alkyl or fluoro-lower alkyl; and wherein R 2 is hydrogen, lower alkyl, lower alkenyl lower alkoxy, halogen, —NR′R″, pyrrolidin-1-yl, piperidin-1-yl, morpholine-4-yl, fluoro-lower alkyl, fluoro-lower alkoxy, or lower alkoxy-(ethoxy) m ; m is 1, 2, 3 or 4; R′ is hydrogen, lower alkyl or C 3 -C 6 -cycloalkyl; R″ is hydrogen, lower alkyl or C 3 -C 6 -cycloalkyl; Y is —CH═ or ═N—; R 3 is a six-membered aromatic heterocycle containing 1 to 3 nitrogen atoms or a pyridine-N-oxide, which rings are unsubstituted or substituted by one or two substituents selected from the group consisting of halogen, fluoro-lower alkyl, fluoro-lower alkoxy, cyano, amino, lower alkylamino, lower alkoxy-lower alkylamino, lower hydroxy-lower alkylamino, —(CH 2 ) n —C(O)—OR″, —(CH 2 ) n —C(O)—NR′R″, —(CH 2 ) n —SO 2 —NR′R″, —(CH 2 ) n —C(NH 2 )═NR″, hydroxy, lower alkoxy, lower alkylthio, C 3 -C 6 -cycloalkyl and lower alkyl, which is optionally substituted by fluoro, —NR′R″, hydroxy, lower alkoxy, pyrrolidin-1-yl, azetidin-1-yl, cyano or carbamoyloxy, whereby R′ and R″ have the meaning specified above; n is 0, 1, 2, 3 or 4; or a pharmaceutically acceptable addition salt thereof.