Patent ID: 7517538

Claim:
A solid support, comprising at least one surface covalently functionalized with phosphorus-containing dendrimers having a central core that contains at least two functional groups and comprising at their periphery several functions binding said dendrimers to said surface and also allowing the binding or the in situ synthesis of molecules of interest, said dendrimers being between 1 and 20 nm in size, characterized in that the dendrimers are chosen from those consisting of: a central layer in the form of a central core P 0 , optionally containing phosphorus, comprising from 2 to 12 functionalized groups, n intermediate layers, which may be identical or different, each of said intermediate layers consisting of P 1 units corresponding to formula (I) below: in which: L is an oxygen, phosphorus, sulfur or nitrogen atom, M represents one of the following groups: an aromatic group di-, tri- or tetrasubstituted with alkyl groups, alkoxy groups, unsaturated groups of the C 1 -C 12 olefinic, azo or acetylenic type, all these groups possibly incorporating phosphorus, oxygen, nitrogen or sulfur atoms or halogens, or an alkyl or alkoxy group comprising several substituents as defined when M is an aromatic group, R 1 and R 2 , which may be identical or different, represent a hydrogen atom or one of the following groups: alkyl, alkoxy, aryl, optionally comprising phosphorus, oxygen, sulfur or nitrogen atoms or halogens with R 2 usually being different than R 1 , n is an integer between 1 and 11, E is an oxygen, sulfur or nitrogen atom, said nitrogen atom possibly being linked to an alkyl, alkoxy or aryl group, all these groups possibly incorporating phosphorus, oxygen, nitrogen or sulfur atoms or halogens, an external layer consisting of units P 2 , which may be identical or different, and corresponding to formula II below: in which: W represents one of the following groups: alkyl, alkoxy, aryl, all these groups possibly comprising phosphorus, oxygen, nitrogen or sulfur atoms or halogens, X represents an aldehyde, thiol, amine, epoxide, carboxylic acid, alcohol or phenol group.