Patent ID: 8088935

Claim:
A compound of formula I wherein R 1 and R 2 are chosen from hydroxy, C 1 , C 2 , C 3 , C 4 , C 5 , and C 6 straight and branched alkoxy, -G-O(C═O)R 4 , R 5 , —NHR 6 , —OR 7 and —O − X + , wherein X + is a pharmaceutically acceptable cation; R 3 is chosen from hydrogen, —(C═O)R 4 , —(C═O)-G-O(C═O)R 4 , —(C═O)R 5 , —(C═O)NHR 6 and —(C═O)OR 7 ; —O(C═O)R 4 is the deshydrogen residue of a carboxylic acid, the parent of which, R 4 COOH, is chosen from the group consisting of: —(C═O)R 4 is the deshydroxy residue of a carboxylic acid, the parent of which, R 4 COOH, is chosen from the group consisting of: R 5 is —O—R 20 —U, wherein U is chosen from hydrogen, (1,2-dithiolan-3-yl) and phenyl, and R 20 is a divalent C 1 to C 20 alkane or oxaalkane residue; —NHR 6 is the deshydrogen residue of an amine, the parent of which, R 6 NH 2 , is chosen from the group consisting of: —OR 7 is G is chosen from —OCH 2 — and —OCH(CH 3 )—; at least one of R 1 , R 2 and R 3 must be -G-O(C═O)R 4 , —NHR 6 , —OR 7 , —(C═O)R 4 , —(C═O)-G-O(C═O)R 4 , —(C═O)R 5 , —(C═O)NHR 6 or —(C═O)OR 7 R 50 is chosen from C 1 to C 4 alkyl, C 3 to C 4 cycloalkyl, C 1 to C 4 hydroxyalkyl and C 1 to C 4 haloalkyl; Q is chosen from —CH 2 CH═CHCH 2 —, —(CH 2 ) p X(CH 2 ) q —, —O—, —NR 51 — and —(CH 2 ) r A(CH 2 ) s —; p is 2 or 3; q is 1 or 2; X is S(O) x x is 0, 1 or 2; R 51 is H or C 1-6 alkyl; r is 1 or 2; s is 1 or 2; and A is cyclobutyl, phenyl or pyridyl.