Patent ID: 6858628

Claim:
A compound having a structure according to Formula (I): wherein A is alkyl, heteroalkyl, aryl or heteroaryl, substituted or unsubstituted; R 1 alkoxy, NHOR 2 , where R 2 is hydrogen or alkyl; W is one or more of hydrogen, lower alkyl or an alkylene bridge; Y is independently one or more of hydroxy, SR 3 , SOR 4 , SO 2 R 8 , alkoxy, or amino, wherein amino is of formula NR 6 R 7 , wherein R 6 and R 7 are independently chosen from hydrogen, alkyl, heteroalkyl, heteroaryl, aryl, OR 3 , SO 2 R 8 , COR 9 , CSR 10 , and PO(R 11 ) 2 ; or R 6 and R 7 may join together to form a ring; and R 3 is hydrogen, alkyl, aryl, or heteroaryl; R 4 is alkyl, aryl, or heteroaryl; each R 8 is independently alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, diarylamino, or alkylarylamino; R 9 is hydrogen, alkoxy, aryloxy, heteroaryloxy, alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, or alkylarylamino; R 10 is alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, diarylamino, or alkylarylamino; R 11 is alkyl, aryl, heteroaryl, heteroalkyl; Z is hydrogen; hydroxy; alkyl; or an alkylene, or heteroalkylene; n is 2; or an optical isomer, diastereomer or enantiomer for formula (I), or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof.