Patent ID: 7731945

Claim:
A method for unblocking immunization at a lymph node regional to a lesion to be treated in a cancer patient by administering a natural cytokine mixture (NCM) in combination with thymosin α 1 into lymphatics that drain into said lymph node, inducing production of CD 45 RA positive naïve T cells, promoting maturation and activation of dendritic cells in said regional lymph node and allowing presentation by resulting mature dendritic cells of tumor antigen to CD 45 RA positive naïve T cells to gain immunization of the CD 45 RA positive naïve T cells to the tumor antigen, and measuring naïve T cells by detecting CD 45 RA positive T cells, wherein the detection of an increase in CD 45 RA positive naïve T cells correlates with an improved immune response to tumor antigen.