Patent ID: 7160912

Claim:
A compound that is an oxazolidinone derivative of the formula (I) or a salt thereof, or a stereoisomer thereof, where R 1 represents —NHR 4 wherein R 4 represents thio(C 1 –C 10 )acyl, —C(═S)-cyclo(C 3 –C 8 )alkoxy, —C(═S)—(C 1 –C 10 )alkoxy, —C(═S)—(C 2 –C 10 )alkenyloxy, —C(═S)-aryloxy, —(C═S)—S—(C 1 –C 10 )alkyl, —(C═S)—NH 2 , —(C═S)—NH—(C 1 –C 10 )alkyl, —C(═S)—N—((C 1 —C,o)alkyl) 2 , —C(═S)—NH—(C 2 –C 10 )alkenyl, (C═S)—(C═O)—(C 1 –C 10 )alkoxy, —(C═S)—(C═O)-aryloxy, —C(═S)—O—(C═O)—(C 1 –C 10 )alkyl, C(═S)—C(═S)—(C 1 –C 10 )alkyl, —C(═S)—C(═S)-aryl, —C(═S)-thiomorpholinyl or —C(═S)-pyrrolidinyl; R 2 and R 3 , which may be the same or different, are each independently hydrogen, halogen, (C 1 –C 10 )alkyl, halogenated (C 1 –C 10 )alkyl, cyano, nitro, SR a , NR a or OR a , in which R a is hydrogen, (C 1 –C 10 )alkyl or halogenated (C 1 –C 10 )alkyl; is a heterocyclic moiety in which is a 5-membered heterocyclic skeleton, Z represents ═CH, —CH 2 or NR b , where R b is hydrogen or a moiety, which may be substituted or unsubstituted, straight chain or branched, selected from the group consisting of (C 1 –C 10 )alkyl, (C 2 –C 10 )alkenyl, (C 3 –C 8 )cycloalkyl, hydroxy(C 1 –C 10 )alkyl, (C 1 –C 10 )alkylhydroxy, (C 1 –C 10 )alkylamino, amino(C 1 –C 10 )alkyl, (C 1 –C 10 )alkoxy, aryl, aralkyl, aryloxy, (C 1 –C 10 )alkylcarbonyl, arylcarbonyl, (C 1 –C 10 ) alkoxycarbonyl and aryloxycarbonyl; Y 1 represents ═O or ═S group and Y 2 and Y 3 independently represent hydrogen, halogen, cyano, nitro, formyl, hydroxy, amino, ═O, ═S group or substituted or unsubstituted groups selected from (C 1 –C 10 )alkyl, hydroxy(C 1 –C 10 )alkyl, (C 1 –C 10 )alkylhydroxy, (C 1 –C 10 )alkoxy(C 1 –C 10 )alkyl, (C 1 –C 10 )alkylcarbonyl, (C 1 C 10 )alkoxycarbonyl, arylcarbonyl, carboxy(C 1 –C 10 )alkyl, (C 1 –C 10 )alkylsulfonyl, C 1 –C 10 )alkylcarbony(C 1 –C 10 )alkyl, arylcarbonylamino(C 1 –C 10 )alkyl, (C 1 –C 10 )alkylcarbonyloxy(C 1 –C 10 )alkyl, amino(C 1 –C 10 )alkyl, mono(C 1 –C 10 )alkylamino, di(C 1 –C 10 )alkylamino, arylamino, (C 1 –C 10 )alkoxy, aryl, aryloxy, aralkyl, heteroaryl, heteroaralkyl, heterocyclyl or heterocycloalkyl; Y 2 and Y 3 when present on adjacent carbon atoms together may also form a substituted or unsubstituted 5 or 6 membered aromatic or non-aromatic cyclic structure, optionally containing one or two hetero atoms selected from oxygen, sulfur and nitrogen.