Patent ID: 8148557

Claim:
A microbial method of producing Δ 5 -Tibolone (C 21 H 28 O 2 ), 6β-Hydroxy-Δ 4 -tibolone (C 21 H 28 O 3 ), 6α-Hydroxy-Δ 4 -tibolone (C 21 H 28 O 3 ), 15α-Hydroxy-Δ 4 -tibolone (C 21 H 28 O 3 ), 6α-Hydroxy-Δ 1,4 -tibolone (C 21 H 28 O 3 ) and 6β-Methoxy-Δ 4 -tibolone (C 22 H 30 O 3 ) by growing Gibberella fujikuroi (ATCC 10704) in a nutrient media containing tibolone.