Patent ID: 7709445

Claim:
A colloidal suspension comprising submicronic particles, wherein the particles: comprise at least one amphiphilic copolymer comprising at least one block of hydrophilic polyalkylene glycol polymer and at least one linear, α-peptide-linked copolyamino acid comprising at least one block of hydrophilic amino acid monomers with one or more ionizable chains which are at least partially ionized and having an absolute length of greater than or equal to 5 IAA monomers and a block of hydrophobic amino acid monomers having an absolute length of greater than or equal to 5 OAA monomers, wherein the copolyamino acid has a block structure; are individualized supramolecular arrangements; are in a nondissolved state; will spontaneously associate with at least one active principle by adsorption, and without the aid of organic solvents or surfactants, when at least one active principle is added to the colloidal suspension; and release of the at least one active principle is in either or both a sustained manner or a delayed manner.