Patent ID: 7622114

Claim:
A method for aiding in the differential diagnosis of ischemic versus hemorrhagic stroke comprising: a) obtaining a test sample of blood, plasma or serum from a human subject at the time said subject is suspected of suffering from an ischemic or hemorrhagic stroke; b) analyzing the obtained test sample for the amount of (i) NR2A N-terminal domain fragment peptide having SEQ ID NO: 3 and NR2B N-terminal domain fragment peptide having SEQ ID NO: 12 (NR2A-B receptor peptides) or (ii) NR2 antibody that binds NR2A N-terminal domain fragment peptide having SEQ ID NO: 3; c) comparing the result of step (b) with a corresponding reference amount of said NR2A-B receptor peptides or NR2 antibody, or a combination thereof, wherein the corresponding reference amount is derived from a population of apparently healthy human subjects; and d) if the amount determined in step (b) exceeds the corresponding reference amount, diagnosing said human as having an increased probability of having an ischemic stroke over hemorrhagic stroke.