Patent ID: 7879873

Claim:
A compound of the formula (I) wherein W is carbon and Y is nitrogen or, W is nitrogen and Y is carbon; Ar 1 is carbocycle, heteroaryl or heterocyclyl each optionally substituted by one to three R a ; Ar 2 is carbocycle, heteroaryl or heterocyclyl, each optionally substituted by one to three R b ; R 1 is hydrogen, C 1-6 alkyl or C 1-6 alkoxyC 1-6 alkyl; R 2 , R 3 are each independently hydrogen, C 1-6 alkyl or C 1-6 alkenyl, wherein the C 1-6 alkyl or alkenyl is optionally partially or fully halogenated or substituted with one to three groups independently selected from cyano, C 1-6 alkoxy, hydroxyl, —CO 2 C 1-6 alkyl, —C(O)N(R e )(R f ), —N(R e )(R f ) and heterocyclyl optionally substituted by oxo; R a is C 1-6 alkyl, C 3-10 cycloalkyl, C 1-6 alkoxy, C 1-6 alkylthio, C 1-6 alkylsulfonyl, C 1-6 alkoxycarbonyl, amino, mono- or di-C 1-6 alkylamino, C 3-6 cycloalkylamino, C 1-6 alkylaminocarbonyl, C 1-6 acyl, C 1-6 acylamino, C 1-6 dialkylaminocarbonyl, hydroxyl, halogen, cyano, nitro, oxo, R 4 —S(O) m —NH—, R 4 —NH—S(O) m —, aryl or carboxyl; R b is hydroxyl, carboxyl, halogen, —(CH 2 ) n —CN, —(CH 2 ) n —CO 2 C 1-6 alkyl, nitro, —SO 3 H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-10 cycloalkyl, C 1-6 alkoxy, C 1-6 alkylC(O)—, —(CH 2 ) n —NR c R d , R 4 —S(O) m (CH 2 ) 0-1 —, R 4 —S(O) m —NR e —, R 4 —NR e —S(O) m (CH 2 ) 0-1 —, —NR f —C(O)—R e , —(CH 2 ) x —C(O)—(CH 2 ) n —NR c R d , heterocyclyl, aryl or heteroaryl, each R b where possible is optionally halogenated or substituted with 1 to 3 C 1-6 alkyl, hydroxyl, C 1-6 acyl, C 1-6 alkoxycarbonyl, C 1-6 alkyl-S(O) m —, aryl or carboxyl; each R e , R d are independently hydrogen, C 1-6 alkyl, C 1-6 acyl, C 3-10 cycloalkyl, C 1-6 alkoxy, hydroxyC 1-6 alkyl, cyano-C 1-6 alkyl, C 1-6 alkylC 1-6 alkoxy, C 1-6 alkylsulfonyl, C 1-6 alkoxycarbonylC 0-3 alkyl, —(CH 2 ) n —C(O)—NR e R f or —(CH 2 ) n —NR e R f ; each R e , R f are independently hydrogen, C 1-6 alkyl, C 3-10 cycloalkyl, C 1-6 alkoxy, C 1-6 alkoxyC 1-6 alkyl, mono- or diC 1-6 alkylaminoC 1-6 alkyl, hydroxyC 1-6 alkyl or C 1-6 acyl; R 4 is hydrogen, C 1-6 alkyl, C 3-6 cycloalkyl, heterocyclyl(CH 2 ) 0-1 , mono- or di-C 1-6 alkylamino, mono- or di- 1-6 alkylamino(CH 2 ) 2-3 N(R e )—, aryl or heteroaryl each optionally substituted with 1 to 3 C 1-6 alkyl, C 3-6 cycloalkyl, C 1-6 alkoxy, halogen, hydroxyl, oxo, carboxyl, —C(O)NR e R f , amino, mono- or di-C 1-6 alkylamino, C 1-6 alkoxycarbonyl or C 1-6 acylamino; each n, x are independently 0-3; each m is independently 0-2; or a pharmaceutically acceptable salt thereof.