Patent ID: 7495027

Claim:
An ecto- or endoparasiticidal composition which comprises a pharmaceutically acceptable carrier and an effective amount of a compound of formula I wherein R is H, COR 4 or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, benzyl, aryl or heteroaryl group each optionally substituted; R 1 is phenyl optionally substituted with one, two or three halogen, CN, OR 3 , COR 4 , SO 2 R 5 , NR 6 SO 2 R 7 , NR 8 COR 9 , NR 10 R 11 , C 1 -C 6 haloalkyl or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl or C 2 -C 6 alkynyl group each optionally substituted, biphenyl optionally substituted with one, two or three halogen, CN, OR 3 , COR 4 , SO 2 R 5 , NR 6 SO 2 R 7 , NR 8 COR 9 , NR 10 R 11 , C 1 -C 6 haloalkyl or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl or C 2 -C 6 alkynyl group each optionally substituted, or naphthyl optionally substituted with one, two or three halogen, CN, OR 3 , COR 4 , SO 2 R 5 , NR 6 SO 2 R 7 , NR 8 COR 9 , NR 10 R 11 , C 1 -C 6 haloalkyl or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl or C 2 -C 6 alkynyl group each optionally substituted, or heteroaryl optionally substituted with one, two or three halogen, CN, OR 3 , COR 4 , SO 2 R 5 , NR 6 SO 2 R 7 , NR 8 COR 9 , NR 10 OR 11 , C 1 -C 6 haloalkyl or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl or C 2 -C 6 alkynyl group each optionally substituted; R 2 is a phenyl or biphenyl group substituted with one or two halogen, CN or CF 3 groups; R 3 , R 4 , R 9 , R 12 , R 13 and R 18 are each independently H, C 1 -C 8 , haloalkyl, or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, benzyl, aryl or heteroaryl group each optionally substituted; R 5 , R 7 , R 14 and R 16 are each independently a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkyl, benzyl, aryl or heteroaryl group each optionally substituted; R 6 , R 8 , R 15 and R 17 are each independently H or an optionally substituted C 1 -C 6 alkyl group; and R 10 , R 11 , R 19 and R 20 are each independently H, C 1 -C 6 , haloalkyl, or a C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, benzyl, aryl or heteroaryl group each optionally substituted or R 10 and R 11 or R 19 and R 20 may be taken together with the atom to which they are attached to form an optionally substituted 5- to 7-membered ring optionally containing one or two additional heteroatoms selected from N, O or S; or a stereoisomer thereof, a tautomer thereof or a pharmaceutically acceptable salt thereof.