Patent ID: 6916662

Claim:
A method for calculating the value of MCV for a fresh sample of blood, where MCV represents eryhrocyte mean cell volume and fresh means that venipuncture to obtain the sample of blood has occurred less than four hours prior to the measurement of MCV, said method comprising the steps of: (a) providing a sample of blood aged for at least 16 hours; (b) determining at least the following hematology parameters of the sample: MCV, MCH, where MCH represents erythrocyte mean cell hemoglobin, and MCHC, where MCHC represents erythrocyte mean cell hemoglobin concentration; (c) calculating the value of MCHC of said sample of blood that would have been expected for said sample when said sample was fresh, said value of MCHC that would have been expected for said sample of blood when said sample was fresh being derived from the value of MCH determined in step (b) by means of an equation derived from a regression relationship of MCH as a function of MCHC; (d) comparing said value of MCHC that would have been expected for said sample of blood when said sample of blood was fresh with the value of MCHC determined; and (e) correcting said value of MCV determined in step (b) in order to determine the value of MCV for the sample of blood when said sample was fresh, said correcting being performed by multiplying the value of MCV determined in step (b) by the ratio of the value of MCHC determined in step (b) to the calculated value of MCHC determined in step (c), wherein the calculated value of MCHC is equal to“a” times the value of MCH determined in step (b) plus “b”, where“a” represents a constant and “b” represents a constant and “a” and “b” are derived from the regression relationship of MCH as a function of MCHC.