Patent ID: 8372862

Claim:
A method for or treating osteoporosis in a mammal, comprising administering a compound selected from the group consisting of the following compounds: {2-ethyl-7-methyl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridin-5-yl}methanol; 2-butyl-5-methyl-6-pyridin-3-yl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine; methyl 2-butyl-6-pyridin-2-yl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine-5-carboxylate; {2-butyl-7-methyl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridin-5-yl}methanol; 2-butyl-5-fluoromethyl-6-(1-oxypyridin-2-yl)-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine; (2-butyl-5-dimethoxymethyl-3-{2′-[1-(1-ethoxyethyl)-1H-tetrazol-5-yl]biphenyl-4-ylmethyl}-3H-imidazo[4,5-b]pyridin-6-yl)phenylmethanol; {2-butyl-5-dimethoxymethyl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridin-6-yl}phenylmethanol; 6-bromo-2-butyl-3-{2′-[1-(1-ethoxyethyl)-1H-tetrazol-5-yl]biphenyl-4-ylmethyl}-3H-imidazo[4,5-b]pyridin-5-ylmethyl acetate; 6-bromo-2-butyl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridin-5-ylmethyl acetate; 2-butyl-7-methyl-5-((methylsulfanylmethoxy)methyl)-6-phenyl-3-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine; methyl 2-butyl-6-styryl-1-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-benzimidazol-5-carboxylate; and methyl 2-butyl-5-styryl-1-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-benzimidazol-6-carboxylate, or a pharmaceutical acceptable salt thereof to the mammal in need thereof.