Patent ID: 8304449

Claim:
A method for the treatment of cancer in a mammal in need thereof, comprising administering to said mammal an effective amount of a compound of the formula (Ig), or a stereoisomer, optical isomer, a pharmaceutically acceptable salt, or a pharmaceutically acceptable solvate thereof; wherein: R 1 is phenyl, which is unsubstituted or substituted by 1, 2, or 3 identical or different substituents selected from: halogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, nitro, SR 11 , trifluoromethyl, hydroxyl, cyano, carboxy, C 1 -C 4 alkoxycarbonyl and —C 1 -C 4 -alkylenehydroxyl, R 2 , and R 4 are hydrogen; R 3 and R 5 are hydroxy or C 1 -C 4 alkoxy; Z is O; A is a saturated 5-membered ring represented by the following formula (i); R 6 is —C 1 -C4-alkyleneOR 11 ; R 11 is hydrogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkanoyl, or C 1 -C 4 -alkoxycarbonyl; and R 13 is hydrogen or C 1 -C 4 -alkyl; wherein said cancer is selected from the group consisting of breast cancer, lung cancer, cancer of the cervix, prostate cancer and hystiolytic lymphoma.