Patent ID: 7375101

Claim:
A compound of Formula (I), or pharmaceutically acceptable salt, diastereomer, or enantiomer thereof: wherein R 1 is selected from optionally substituted acyl, optionally substituted alkyloxycarbonyl, optionally substituted alkyl, optionally substituted heteroalkyl, optionally substituted cycloalkyl, optionally substituted naphthyl, optionally substituted isoquinolyl, optionally substituted acridinyl, optionally substituted coumarinyl, optionally substituted carbazolyl, optionally substituted heterocyclyl, optionally substituted aryl-C 1-6 alkyl, and optionally substituted heterocyclyl-C 1-6 alkyl; X is —NHC(═S)N(R 2 )—; R 3 is substituted aryl, optionally substituted C 1-12 alkyl, optionally substituted C 3-12 cycloalkyl, or optionally substituted heterocyclyl; R 4 is, at each position, independently halogen, optionally substituted alkyl, optionally substituted heteroalkyl, nitro, cyano, hydroxy, —OR 6 , —SR 6 , —S(═O)R 6 , —S(═O) 2 R 6 , —C(═O)R 6 , —C(═S)R 6 , —NR 7 R 6 , —C(═O)NR 7 R 6 , —NR 7 C(═O)R 6 , —SO 2 NR 7 R 6 , —NR 7 SO 2 R 6 , or —C(═O)OR 6 ; R 5 , R 6 and R 7 are independently —H, or optionally substituted C 1-6 alkyl; and R 2 is selected from —H, optionally substituted C 1-12 alkyl, optionally substituted C 1-12 heteroalkyl, substituted aryl, and optionally substituted heterocyclyl.