Patent ID: 7892297

Claim:
A cyanine modified with an alkynyl-linker arm, selected from the group consisting of: wherein M is a counterion; R 8 is a linear, saturated or unsaturated alkyl chain, having from 1 to 30 carbon atoms, wherein one or more carbon atoms are each optionally substituted by a component independently selected by an oxygen or a sulfur atom, a —NH— or a —CONH— group, or a cyclic 4-, 5- or 6-membered grouping of carbon atoms, aromatic or not aromatic, wherein one or more carbon atoms are each optionally substituted by a heteroatom independently selected from oxygen, sulfur, nitrogen or selenium; Q is a polymethinic chain selected from: wherein R 7 is selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, phenoxy, thiophenoxy, anilino, cyclohexylamino, piridine, —R 8 —Y, —O—R 8 —Y, —S—R 8 —Y, —NH—R 8 —Y, wherein Y is selected from the group consisting of carboxyl, carbonyl, amino, sulphydryl, thiocyanate, isotyocianate, isocyanate, maleimide, hydroxyl, iodoacetamido, hydrazine, aldehyde, nitrophenyl, dinitrophenyl, and trinitrophenyl, R 8 is as defined above, and aryl optionally substituted by one or more substituents independently selected from the group consisting of —SO 3 H, carboxyl (—COOH), amino (—NH 2 ), carbonyl (—CHO), thiocyanate (—SCN), isothiocyanate (—CNS), epoxy and —COZ wherein Z represents a leaving group; and n is an integer between 1 and 100.