Patent ID: 8021895

Claim:
A method for the diagnosis and/or prognosis of renal damage in a human patient, said renal damage being caused by chronic transplant rejection following renal transplantation, the method comprising (i) detecting the amount of at least one marker protein in a sample from said patient, said patient sample being selected from the group consisting of blood sample, serum sample, plasma sample and urine sample; (ii) comparing the amount of said at least one marker protein to a control sample, wherein an alteration of the amount of said marker protein in said patient sample, compared to the control sample, is indicative of renal damage; wherein said at least one marker protein is selected from the group consisting of N-acetylmuramoyl-L-alanine amidase precursor, adiponectin, AMBP protein precursor (α 1 -microglobulin), C4b-binding protein α-chain precursor, ceruloplasmin precursor, complement C3 precursor, complement component C9 precursor, complement factor D precursor, α 1B -glycoprotein, B 2 -glycoprotein I precursor, heparin cofactor II precursor, Ig μ Chain C region protein, Leucine-rich α 2 -glycoprotein precursor, pigment epithelium-derived factor precursor, plasma retinol-binding protein precursor and translation initiation factor 3 subunit 10.