Patent ID: 7998684

Claim:
A screening method for a compound or a salt thereof that promotes the binding of (a) a complex comprising a protein comprising an amino acid sequence at least 50% identical to SEQ ID NO: 23 or a partial peptide or salt thereof; and (b) a protein comprising an amino acid sequence at least 50% identical to SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3 or a partial peptide or salt thereof, comprising: (I) providing cultures of cells which express the protein (b); (II) contacting some of the cultures with a test compound; (III) precipitating the complex (a) from the cultures; (IV) measuring the amounts of protein (b) co-precipitated with the complex (a) in the presence and absence of the test compound; and (V) comparing the measurement in the presence of the test compound with the measurement in the absence of the test compound, wherein a 20% or greater increase in co-precipitation in the presence of the test compound indicates that the test compound promotes the binding of (a) and (b).