Patent ID: 7618963

Claim:
A bicyclic heteroaromatic compound according to general formula I, or a pharmaceutically acceptable salt thereof, wherein R 1 is (3-8C)cycloalkyl, (2-7C)heterocycloalkyl, (6-14C)aryl or (4-13C)heteroaryl; all optionally substituted with one or more substituents selected from N(R 4 )R 5 , NHR 5 , R 5 , OR 5 and/or SR 5 ; R 2 is (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (6-14C)aryl or (4-13C)heteroaryl; R 3 is (1-8C)alkyl, (3-8C)cycloalkyl, (2-7C)heterocycloalkyl, (6-14C)aryl or (4-13C)heteroaryl; R 4 can be selected from the same groups as described for R 2 , R 5 is (2-7C)heterocycloalkylcarbonyl, (2-8C)alkenylsulfonyl, (2-8C)alkenoxycarbonyl, (6-14C)arylsulfonyl, (6-14C)arylaminocarbonyl, (6-14C)aryloxycarbonyl, (6-14C)arylaminosulfonyl, (6-14C)aryloxysulfonyl, or (1-8C)alkylsulfonyl, (1-8C)(di)alkylaminocarbonyl, (1-8C)alkoxycarbonyl, (1-8C)(di)alkylaminosulfonyl, or (1-8C)alkoxysulfonyl, the alkyl group of which may be optionally substituted with one or more substituents selected from hydroxyl, (1-8C)alkoxy, (2-7C)heterocycloalkyl(1-8C)alkoxy, (3-8C)cycloalkyl(1-8C)alkoxy, (6-14C)aryl(1-8C)alkoxy, (4-13C)heteroaryl(1-8C)alkoxy, (2-7C)heterocycloalkyl, (3-8C)cycloalkyl, (6-14C)aryl, (4-13C)heteroaryl, (1-8C)alkoxycarbonyl, (6-14C)aryloxycarbonyl, (1-8C)alkylcarbonyloxy, (6-14C)arylcarbonyloxy, (1-8C)alkylcarbonyl, (6-14C)arylcarbonyl, amine, (1-8C)alkylaminocarbonyl, (6-14C)arylaminocarbonyl, (1-8C)alkylcarbonylamino, (6-14C)arylcarbonylamino, (6-14C)(di)arylamino, (di)[(1-3C)alkoxy(1-3C)alkyl]amino and/or (1-8C)(di)alkylamino; Y is N; Z is NH 2 or OH; A is S, N(H), N(R 4 ), O or a bond; B is N(H) or a bond; and X1-X2 is S or O.