Patent ID: 8463373

Claim:
A method of providing transdermal delivery of a plurality of doses of a charged therapeutic substance comprising: (a) providing a skin-worn device comprising: (1) a donor reservoir containing an amount of a therapeutic substance to be delivered transdermally by iontophoresis, said donor reservoir further including circuit elements configured to deliver a plurality of successive doses of a therapeutic substance by sequentially selectively connecting a plurality of separate sources of reactive material in said circuit in a manner such that each dose is delivered by a different source of reactive material; (2) a counter reservoir; (3) a source of electric power connected in a circuit between said donor reservoir and said counter reservoir; and (4) a control system for controlling current flow in said circuit and configured to enable the plurality of successive doses of said therapeutic substance to be administered from said donor reservoir; (b) applying said skin-worn device to the skin of a patient; and (c) using said control system to control current flow in said circuit to provide a plurality of doses of said therapeutic substance.