Patent ID: 7872005

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R 1 is —N(R c )(CH 2 ) n R c ; cycloalkyl, aryl, or heteroaryl; for each occurrence, each of R 2 and R 4 , independently, is R c , halogen, nitro, cyano, isothionitro, SR C , or OR c ; or R 2 and R 4 , taken together, is carbonyl, R 3 is R c , alkenyl, alkynyl, OR c , OC(O)R c , SO 2 R c , S(O)R c , S(O 2 )NR c R d , SR c , NR c R d , NR c COR d , NR c C(O)OR d , NR c C(O)NR c R d , NR c SO 2 R d , C(O)R c , C(O)R c , C(O)OR c , or C(O)NR c R d ; P(O)OR c OR d ; S(O) 2 NR c R d ; R 5 is H or alkyl; R 6 is Each n is independently 0, 1, 2, 3, 4, 5, or 6; G is: Hydrazide; Hydrazone; Hydrazine; Hydroxylamine; Oxime; Carbamate; Thiocarbamate; Guanidine; Alkylguanidine; —NR c —C(NR c )—NH—; Cyanoguanidine; Sulfonylguanidine; —NR c —C(NSO 2 R d )—NH—; Nitroguanidine; Acylguanidine; Urea; —NR c —C(O)—NR c —; Thiourea; —NR c —C(S)—NR c —; —NH—S(O) 2 —NH—; —NR c —S(O) 2 —NR c —; Sulfonamide; Phosphoryl; -Heteroaryl-S—; —C(N—CN)—NR c —; —Si(OH) 2 —; —B(OH)— —C(NR d )—NR c —; —N(R c )—CHR d —C(O)—; —C(O)—ON (R c )—; —C(O)—N(R c )O—; —C(S)—ON(R c )—; —C(S)—N(R c )O—; —C(N(R d ))—ON(R c )—; —C(N(R d ))—NR c O—; —OS(O) 2 —N(R c )N(R c )—; —OC(O)—N(R c )N(R c )—; —OC(S)—N(R c )N(R c )—; —OC(N(R d ))—N(R c )N(R c )—; —N(R c )N(R c )S(O) 2 O—; —N(R c )N(R c )C(S)O—; —N(R c )N(R c )C(N(R d ))O—; —OP(O) 2 O—; —N(R c )P(O) 2 O—; —OP(O) 2 N(R c )—; —N(R c )P(O) 2 N(R c )—; —P(O) 2 O—; —P(O) 2 N(R c )—; —N(R c )P(O) 2 —; —OP(O) 2 —; —O-alkyl-heterocyclyl-N(R c )—; —N(R c )CHR d C(O)N(R c )CHR d C(O)—; —N(R c )CHR d C(O)—; —N(R c )C(O)CHR d —; or —C(O)N(R c )CHR d C(O)—; X is O, S, S(O), S(O 2 ), N(SO 2 R c ), or NR c ; Y is a covalent bond, CH 2 , C(O), C═N—R c , C═N—OR c , C═N—SR c , O, S, S(O), S(O 2 ), or NR c ; Z is N or CH; U is N and V is CR c ; and W is O, S, S(O), S(O 2 ), NR c , or NC(O)R c ; wherein each of R a and R b , independently, is H, alkyl, aryl, heteroaryl; and each of R c , and R d , independently, is H, alkyl, aryl, heteroaryl, cyclyl, heterocyclyl, —S(O) 2 R d , or alkylcarbonyl.