Patent ID: 8262612

Claim:
An apparatus to prevent reperfusion injury within an arterial vessel, the apparatus comprising: an elongated catheter having a proximal region and a distal region, the distal region for advancement within an arterial vessel to a region proximal to a lesion; having only a single expandable member coupled to the elongated catheter near the distal region occludes blood flow proximal to the lesion causing blockage of blood flow to an ischemic region distal to the lesion; and an infusion catheter disposed within a first lumen formed within the elongated catheter, the infusion catheter slideable within the first lumen to extend a substantial length past the distal region of the elongated catheter, wherein the infusion catheter releases an anti-reperfusion drug through a distal tip opening in a distal terminal end of the infusion catheter, wherein, during release, an outer surface of the infusion catheter is exposed through the lesion, and the exposed outer surface has a diameter small enough to advance through the lesion without causing a large channel or reperfusion pathway to form through the lesion.