Patent ID: 7312241

Claim:
A compound of the formula: or a pharmaceutically acceptable salt, solvate or hydrate thereof, wherein: one of R 1 and R 2 is —CN, and the other is —H, substituted or unsubstituted lower alkyl, substituted or unsubstituted alkenyl, or substituted or unsubstituted alkynyl; each occurrence of R c and R d is independently —H, substituted or unsubstituted lower alkyl, or substituted or unsubstituted alkoxy; R 3 is substituted or unsubstituted lower alkyl substituted or unsubstituted alkoxy or R 3 with R 4 , together form —O—(C(R 16 R 17 )) 2 —O —; R 4 is substituted or unsubstituted lower alkyl or substituted or unsubstituted alkoxy; R 5 is substituted or unsubstituted lower alkyl or substituted or unsubstituted alkoxy; R 6 is —H, substituted or unsubstituted lower alkyl or substituted or unsubstituted alkoxy; R 7 is —H, substituted or unsubstituted lower alkyl or substituted or unsubstituted alkoxy; R 8 is —H, substituted or unsubstituted lower alkyl substituted or unsubstituted alkoxy, or R 8 with either R c or with R 7 , together form —O—(C(R 16 R 17 )) 2 —O—; each occurrence of R 16 and R 17 is independently —H or halogen, wherein either R 3 with R 4 , together form —O—(C(R 16 R 17 )) 2 —O— or R 8 with either R c or with R 7 , together form —O—(C(R 16 R 17 )) 2 —O—.