Patent ID: 7799845

Claim:
A polymeric ophthalmic or otorhinolaryngological device material comprising a) 65 to 95% (w/w) of a monofunctional acrylate or methacrylate monomer of formula [1]: wherein B=—O(CH 2 ) n —, —(OCH 2 CH 2 ) n —; —NH(CH 2 ) n —, or —NCH 3 (CH 2 ) n —; R 1 =H, CH 3 , CH 2 CH 3 , or CH 2 OH; n=0-12; A=C 6 H 5 or O(CH 2 ) m C 6 H 5 , where the C 6 H 5 group is optionally substituted with —(CH 2 ) n H, —O(CH 2 ) n H, —CH(CH 3 ) 2 , —C 6 H 5 , —OC 6 H 5 , —CH 2 C 6 H 5 , F, Cl, Br, or I; and m=0-18; b) a difunctional acrylate or methacrylate cross-linking monomer of formula [2]: wherein R 2 , R 3 independently=H, CH 3 , CH 2 CH 3 , or CH 2 OH; W, W′ independently=O(CH 2 ) d , NH(CH 2 ) d , NCH 3 (CH 2 ) d , O(CH 2 ) d C 6 H 4 , O(CH 2 CH 2 O) d CH 2 , O(CH 2 CH 2 CH 2 O) d CH 2 , O(CH 2 CH 2 CH 2 CH 2 O) d CH 2 , or nothing; J=(CH 2 ) a , O(CH 2 CH 2 O) b , O, or nothing, provided that if W and W′=nothing, then J≠nothing; d=0-12; a=1-12; and b=1-24; and c) 5 to 35% (w/w) of a di-block or tri-block macromer of formula [3a], [3b], [3c], [3d], or [3e]: wherein for formulas [3a], [3b], [3c], [3d], and [3e] a independently=1-18; Z 1 =—(OCH 2 CH 2 ) p O—, —(OCH 2 CH(CH 3 )) p O—, —(NHCH 2 CH 2 ) p NH—, or —N(COR 7 )CH 2 CH 2 ) p O; X=O, NH—, N(CH 3 )—, N(CH 2 CH 3 )—, or N(C 6 H 5 )—; Y=—(CH 2 ) a H, —CH 2 C(CH 3 ) 2 ; —CH 2 CH 2 N(C 6 H 5 ) 2 , —CH 2 CH(OH)CH 2 OC 6 H 5 , —(CH 2 CH 2 O) p C 6 H 5 , —(CH 2 ) t C 6 H 5 , or —(CH 2 ) t OC 6 H 5 ; Z 2 —(OCH 2 CH 2 ) p O—, —(OCH 2 CH(CH 3 )) p O—, —(NHCH 2 CH 2 ) p NH—, or —O(CH 2 CH 2 (COR 7 )N) p —R 8 —(N(COR 7 )CH 2 CH 2 ) p O—; R 4 , R 5 , R 6 independently=H, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , CH(CH 3 ) 2 , CH 2 CH 2 CH 2 CH 3 , or CH 2 CH(CH 3 ) 2 ; R 7 =CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , CH(CH 3 ) 2 , CH 2 CH 2 CH 3 , or CH 2 CH(CH 3 ) 2 ; R 8 =CH 2 , (CH 2 ) 2 , (CH 2 ) 3 , (CH 2 ) 4 , (CH 2 ) 5 , or (CH 2 ) 6 ; p=1-500; e=1-200, provided that p≧e; t=0-6; R 9 =CH 2 ═C(R 6 )C(O)—, CH 2 ═C(R 6 )CO 2 CH 2 CH 2 NHC(O)—, or CH 2 ═CHC 6 H 4 C(O)CH 2 ═CHC 6 H 4 CH 2 ; and L=H, Cl, Br, —CH 2 C(O)CH 3 , CH 2 C(O)C(CH 3 ) 3 , —CH 2 C(O)C 6 H 5 , —CH 2 C(O)C 6 H 4 OH, —CH 2 C(O)C 6 H 4 OCH 3 , or CH 2 CH═CH 2 .