Patent ID: 7112671

Claim:
A texaphyrin of Formula II: its hydrate, pharmaceutically acceptable salt, or a pro drug form thereof wherein, M is a monovalent, divalent, trivalent, or tetravalent metal cation; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently chosen from the group consisting of hydrogen, halogen, hydroxyl, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted haloalkyl, nitro, acyl, optionally substituted alkoxy, saccharide, optionally substituted amino, carboxyl, optionally substituted carboxyalkyl, optionally substituted carboxyamide, optionally substituted carboxyamidealkyl, optionally substituted heterocycle, optionally substituted cycloalkyl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl, optionally substituted heterocycloalkylalkyl, and the group —X—Y, in which X is a covalent bond or a linker and Y is a catalytic group, a chemotherapeutic agent, or a with the proviso that R 1 is different from R 6 , R 2 is different from R 5 and R 5 does not represent (CH 2 ) 2 —CO—N ((CH 2 ) 2 —OH) 2 , CH 2 CH 3 , or (CH 2 ) 2 —CO—N(CH 3 )(CH 2 —(CHOH) 4 —CH 2 —OH); AL is an apical ligand; and n is an integer of 1–5.