Patent ID: 8420306

Claim:
A method of identifying a dividing cell in a population of mammalian cells, the method comprising: obtaining a population of mammalian cells comprising at least one cell suspected of being a dividing cell; detecting a cell having one or more midbody scars by a method comprising contacting the population of mammalian cells with an antibody or an antigen-binding portion thereof that binds specifically to a polypeptide component of a midbody scar selected from the group consisting of: mitotic kinesin-like protein 1 (MKLP1), Epsilon tubulin (ε-tubulin), Centrosomal Protein 55KDa (Cep55), and Aurora B kinase, and detecting binding of the antibody or antigen-binding portion thereof to the polypeptide component, wherein a ring structure not at a midbody or centrosome is the midbody scar; and identifying the cell having one or more midbody scars as the dividing cell.