Patent ID: 8105626

Claim:
A capsule comprising lansoprazole-containing granules, wherein said granules comprise: a principal ingredient layer comprising lansoprazole or an optically active isomer thereof or a pharmaceutically acceptable salt thereof in an amount of 12% by weight or more based on the total granules, and one or more basic inorganic salts in an amount of 0.2 part by weight to 0.4 part by weight based on 1 part by weight of lansoprazole or the optically active isomer thereof or the pharmaceutically acceptable salt thereof; an intermediate coating layer which is formed on the principal ingredient layer; an enteric coating layer which is formed on the intermediate coating layer; and a core; wherein: the principal ingredient layer is formed on the core, the amount of the intermediate coating layer to be coated is 0.02 part by weight to 1.5 parts by weight on 1 part by weight of the granules containing lansoprazole or the optically active isomer thereof or the pharmaceutically acceptable salt thereof, the amount of the enteric coating layer to be coated is 10% by weight to 70% by weight based on the total amount of the granules before coating of the enteric coating, and the average particle size of the granules is 600 μm to about 2500 μm.