Patent ID: 7811816

Claim:
An isolated CD8 + T cells that are specifically cytotoxic for a target cell, wherein the target cell has on its surface one or more non-tumor self antigenic peptides associated with Class I MHC molecules, wherein said self-antigenic peptides are peptides from human IgE protein and are selected from the group consisting of TQSPSVFPL (SEQ ID NO: 64), SLNGTTMTL (SEQ ID NO: 50), TMTLPATTL (SEQ ID NO:69), TLPATTLTL (SEQ ID NO:67), TLSGHYATI (SEQ ID NO:68), WVDNKTFSV (SEQ ID NO: 51), WLSDRTYTC (SEQ ID NO: 52), ALMRSTTKT (SEQ ID NO: 65), NFMPEDISV (SEQ ID NO: 79), YATISLLTV (SEQ ID NO: 58), TLTVTSTLPV (SEQ ID NO:56), SVQWLHNEV (SEQ ID NO: 76), QWLHNEVQL (SEQ ID NO: 80), TLACLIQNFM (SEQ ID NO: 59), or QVMDVDLSTA (SEQ ID NO: 60), and wherein the CD8 + T cells have been selectively activated by culturing said CD8 + T cells in the presence of antigen presenting cells (APC) having Class I MHC molecules present on their cell surface and wherein said APC are loaded with one of said non-tumor self antigenic peptides.