Patent ID: 6953570

Claim:
A compound comprising the following porphyrin structure: or any pharmaceutically acceptable salt thereof, wherein: R 1 is independently -TPA, -L-TPA, —H, —Ar, —(CH 2 ) n CH 3 , —CH═CH 2 , —(CH 2 O) n -G, -t-Butyl, or —C(O)OG; R 2 is independently -TPA, -L-TPA, —H, —Ar, —(CH 2 ) n CH 3 , —CH═CH 2 , —(CH 2 O) n -G, -t-Butyl, or —C(O)OG; R 3 is independently -TPA, -L-TPA, —H, —Ar, —(CH 2 ) n CH 3 , —CH═CH 2 , —(CH 2 O) n -G, -t-Butyl, or —C(O)OG; or independently R 2 and R 3 are linked by —C 4 H 4 — to form a six-member ring; M is either two hydrogen atoms or a metal ion; each n is independently an integer ranging from 1 to 20; each G is independently —H, or a C 1 to C 20 alkyl; TPA is independently selected from the group consisting of the following structures TPA A through TPA H: wherein in TPA A, R is independently selected from the group consisting of H, alkyl, alkyloxy, and —(OCH 2 CH 2 ) m OG, G is H or alkyl, and m and n independently=1 to 5; wherein in TPA B, R is alkyl, and n=1 to 5; wherein in TPA C, R is independently selected from the group consisting of H, CN, alkyl, and alkyloxy, R′ is independently selected from the group consisting of alkyl, alkyloxyphenyl, phenyl, and phenyl-(OCH 2 CH 2 ) m OG, G is H or alkyl, and m and n independently=1 to 3; wherein in TPA D, R′ is independently selected from the group consisting of alkyl, alkyloxyphenyl, and phenyl-(OGH 2 CH 2 ) m OG, G is H or alkyl, and m and n independently=1 to 5; wherein in TPA E, R is independently selected from the group consisting of H, alkyl, and —OCH 2 CH 2 ) m OG, R′ is alkyl, G is H or alkyl, and m and n independently=1 to 5; wherein in TPA F, R is independently selected from the group consisting of H, alkyl, and —(OCH 2 CH 2 ) m OG, R′ is alkyl, G is H or alkyl, and m and n independently=1 to 3; wherein in TPA G, R is independently selected from the group consisting of H, CN, alkyl, alkyloxy, and —(OCH 2 CH 2 ) m OG, R′ is independently selected from the group consisting of H, alkyl, alkyloxy, and —(OCH 2 CH 2 ) m OG, G is H or alkyl, and m=1 to 6; and wherein in TPA H, R is independently selected from the group consisting of alkyl, phenyl, alkyloxyphenyl, and phenyl-[(OCH 2 CH 2 ) m OG] x , G is H or alkyl, m=1 to 4; and x=1 to 4; wherein in TPA A through TPA H, alkyl is C 1 to C 20 and the selected TPA is attached to the porphyrin structure at the point indicated by the wiggle line; Ar is independently C 6 H 4 X, C 6 H 3 X 2 , C 6 H 2 X 3 , C 6 HX 4 , or C 6 X 5 , wherein X is independently F, Cl, Br, or I; and L is a linking moiety between the porphyrin structure and the TPA and is independently selected from the group consisting of ethenyl, ethynyl, —(CH 2 ) n — where n is equal to 1 to 20, ortho-phenyl, meta-phenyl, para-phenyl, —C(═O)—O—, and 4-phenyl-2′-ethynyl; wherein at least one of R 1 , R 2 or R 3 is a -TPA or -L-TPA moiety, and at least one of R 1 , R 2 or R 3 is not —H or a -TPA or -L-TPA moiety.