Patent ID: 8273304

Claim:
A device comprising: a) a substrate comprising at least one array, wherein the array comprises at least 25 different reactant binding agents each specific for a different target biomolecule in a plurality of target biomolecules, wherein said reactant binding agents are immobilized on a surface of the substrate at discrete, known locations arranged in a two-dimensional array format so that each different reactant binding agent is present at a different known location and wherein the reactant binding agents are synthesized on the surface of the substrate; b) a holder, wherein the substrate comprising the at least one array is attached to a surface of the holder, and wherein said surface of the holder and the at least one array fits within a corresponding sample well of a microtiter plate; and c) a microtiter plate comprising a plurality of sample wells, wherein the holder and the microtiter plate are arranged such that the substrate comprising the at least one array, further comprising the at least 25 different reactant binding agents, is fitted into a single sample well of the microtiter plate.