Patent ID: 8410122

Claim:
A compound having the formula: or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: R 1 is cycloalkyl, which can be unsubstituted or optionally substituted with an alkyl or halo group; R 2 is H, alkyl, halo or —O-alkyl; R 3 is alkyl, cycloalkyl, aryl or heteroaryl, wherein any R 3 group can be unsubstituted or optionally substituted with R 4 ; each occurrence of R 4 represents 1 to 4 substituents, which can be the same or different, and which are selected from alkyl, halo, —CN, —OR 5 , haloalkyl, aryl, heteroaryl, heterocycloalkyl, cycloalkyl, —N(R 5 ) 2 , —S(O) 2 R 6 , —C(O)R 5 , —C(O)OR 5 or —C(O)N(R 5 ) 2 ; each occurrence of R 5 is independently H, alkyl or aryl; each occurrence of R 6 is independently alkyl, aryl, haloalkyl, cycloalkyl, heterocycloalkyl or heteroaryl; each occurrence of R 7 is independently H, alkyl, halo, —CN, —O-alkyl or haloalkyl; each occurrence of R 8 is independently H or alkyl; J is —C(R 7 )— or —N—; K is —C(R 7 )— or —N—; L is —C(R 7 )— or —N—; Q is arylene or heteroarylene, each of which can be unsubstituted or optionally substituted with R 4 ; W is a bond, alkylene, —C(O)—, —C(O)O—, —C(O)NH— or —S(O) 2 —; Y is alkylene, —O— or —N(R 5 )—; Z is alkylene, —O— or —N(R 5 )—; p is 0, 1 or 2; q is 1, 2 or 3, such that the sum of p and q is from 1 to 4; and each occurrence of t is independently 0 or 1.