Patent ID: 7169899

Claim:
A macrocyclic compound of the formula (1): and its pharmaceutically acceptable salts, wherein A 1 is: wherein X 1 is —CH—, and R 1 is A 2 is: wherein X 2 is —CH—, and R 2 is H; A 3 is: wherein X 3 is —CH—, and R 3 is W 1 , W 2 , W 3 , and W 5 are each selected from the group consisting of hydrogen and protecting groups used for orthogonal protection in peptide synthesis; wherein the carbonyl carbon of A 1 is covalently bonded to the nitrogen atom of A 2 , and the carbonyl carbon of A 2 is covalently bonded to the nitrogen atom of A 3 ; T is a radical selected from the group consisting of: wherein (N) is the nitrogen atom of A 1 of formula (1) and (C) is the carbonyl carbon of A 3 of formula (1).