Patent ID: 8703991

Claim:
A method for producing a compound of Formula I wherein n is 1, 2 or 3; R 1 and R 2 are each independently selected from the group consisting of halo, alkyl having one or two carbon atoms, perfluoromethyl, alkoxy having one or two carbon atoms, perfluoromethoxy, and hydroxy; comprising: (a) reacting the corresponding compound of Formula II with a halogenating agent in an ethereal solvent to yield crude compound of Formula III, wherein X is fluoro, chloro, bromo or iodo; (b) reacting the compound of Formula III from the previous step with a malonate ester represented by the formula R 3 OC(O)CH 2 C(O)OR 3 and a base in a solvent, wherein the solvent comprises an alcohol represented by the formula R 3 OH, wherein R 3 is lower alkyl, to yield a crude preparation of the compound of Formula IV; (c) hydrolyzing the compound of Formula IV from step (b) to yield the compound of Formula V; and (d) decarboxylating the compound of Formula V from the previous step to yield the compound of Formula I.