Patent ID: 7235661

Claim:
A compound of formula (II) or a pharmaceutically acceptable salt, or N-oxide, thereof, wherein A is selected from the group consisting V is selected from the group consisting of CR V and N; R V , is independently selected from the group consisting of hydrogen, alkoxy, alkenyl, alkyl, alkylsulfinyl, alkylsulfonyl, alkylthio, alkynyl, alkoxycarbonyl, alkylcarbonyl, alkylcarbonyloxy, carboxy, cyano, formyl, halogen, haloalkoxy, haloalkyl, hydroxy, hydroxyalkyl, mercapto, nitro, —NZ 1 Z 2 , (NZ 3 Z 4 )carbonyl, and (NZ 3 Z 4 )sulfonyl; R Y is selected from the group consisting of hydrogen, alkenyl, alkoxycarbonyl, alkyl, arylalkyl, and (NZ 3 Z 4 )carbonyl; Z 1 and Z 2 are each independently selected from the group consisting of hydrogen, alkyl, alkylcarbonyl, alkylsulfonyl, aryl, arylalkyl, arylalkylsulfonyl, arylsulfonyl, and formyl; Z 3 and Z 4 are each independently selected from the group consisting of hydrogen, alkyl, aryl, and arylalkyl; L is alkylene; D is selected from the group consisting of wherein the left end is attached to L and the right end is attached to B 1 ; R A is selected from the group consisting of hydrogen and alkyl; Z is N; --- is absent; B 1 is selected from the group consisting of R 1 , R 2 , R 3 , R 4 and R 5 are each independently selected from the group consisting of hydrogen, alkoxy, alkenyl, alkyl, alkylsulfinyl, alkylsulfonyl, alkylthio, alkynyl, alkoxycarbonyl, alkylcarbonyl, alkylcarbonyloxy, carboxy, cyano, formyl, halogen, haloalkoxy, haloalkyl, hydroxy, hydroxyalkyl, mercapto, nitro, —NZ 1 Z 2 , (NZ 3 Z 4 )carbonyl, and (NZ 3 Z 4 )sulfonyl; X 1 is selected from the group consisting of N(R 6 ), O and S; Y 1 is selected from the group consisting of C(R 7 ) and N; R 6 is selected from the group consisting of hydrogen and alkyl; and R 7 is selected from the group consisting of hydrogen and alkyl.