Patent ID: 8628951

Claim:
A method of driving a lab-on-a-chip, comprising: preparing a lab-on-a-chip including a first region where a lower substrate and an upper substrate are bonded to each other and a second region where the lower and upper substrates are not bonded to each other, the second region including a gap provided between the lower and upper substrates, the gap having a first distance between the lower substrate and the upper substrate after the lab-on-a-chip is prepared; controlling the gap between the lower and upper substrates at a terminal region of the second region using a gap control member so that the gap has a distance greater than the first distance to control a flow of a fluid in the second region, the terminal region of the second region opposing an interface between the first and second regions; and reducing the gap between the lower and upper substrates using a pressure application member so that the gap has a second distance less than the first distance in a center region of the second region by applying pressure to a portion of the upper substrate in the terminal region of the second region to control a reaction of the fluid in the second region.