Patent ID: 8524778

Claim:
A compound selected from compounds of the following formula and pharmaceutically acceptable salts thereof: wherein: Ar 1 —Ar 2 — is a group of the following formula: q is independently 0, 1, or 2; r is independently 0, 1, 2, or 3; each R P is independently a ring substituent; —R N is independently —H or —R NN ; —R NN is C 1-6 alkyl; —Ar 3 — is independently 1,3-phenylene or 1,4-phenylene, and is optionally substituted with one or more substituents —R AR3 , wherein each —R AR3 is independently a ring substituent; —Z is independently —OH or —O—W; -J- is —R alk —; —R alk — is saturated aliphatic C 1-5 alkylene, and is optionally substituted with one or more substituents —R AA , wherein each —R AA is independently —F, —Cl, —Br, —I, —OH, —OR A2 , —OCF 3 , —NH 2 , —NHR A2 , —NR A2 2 , —C(═O)NH 2 , —C(═O)NHR A2 , or —C(═O)NR A2 2 , wherein each R A2 is independently C 1-4 alkyl; —W is independently —R E1 , —C(═O)—R E2 , or —C(═O)—O—R E3 ; each of R E1 , R E2 , and R E3 is independently —H, C 1-3 alkyl, phenyl, or —CH 2 -phenyl; and each ring substituent is independently —F, —Cl, —Br, —I, —R D9 , —CF 3 , —OH, —OR D9 , —OCF 3 , —CN, —NO 2 , —NH 2 , —NHR D9 , or —NR D9 2 , wherein each —R D9 is independently saturated aliphatic C 1-3 alkyl.