Patent ID: 8260411

Claim:
A catheter for use in a tissue treatment site, the catheter comprising: a. a first conductive member comprising an outer surface, a lumen capable of transporting fluids along a length of the first conductive member, an opening through the first conductive member allowing fluid communication between the lumen and the outer surface of the first conductive member, a proximal insulated portion, and a distal uninsulated portion; b. a proximal second conductive member section having an exterior surface comprising an uninsulated distal portion forming a portion of an exterior surface of the catheter and surrounding the insulated portion of the first conductive member; and c. a semi-permeable membrane having an exterior surface attached to the first conductive member and extending across the opening to regulate fluid passage through the first conductive member, wherein the exterior surface of the proximal second conductive member and the exterior surface of the semi-permeable membrane are co-planar; d. a first conductor in electrical communication with the first conductive member; and e. a second conductor in electrical communication with the second conductive member; wherein when the catheter is inserted into a patient tissue treatment site, electrical current supplied to one of the first or second conductive members passes from the uninsulated portion of the first or second conductive member, through the patient tissue, and to the uninsulated portion of the other of the first or second conductive member to electroporate the tissue at the tissue treatment site; and, wherein the semi-permeable membrane provides the external surface of a fluid collection chamber within the catheter, which in turn permits therapeutic fluid to pass into and through the lumen of the catheter, to the fluid collection chamber, through the semi-permeable membrane, and into the tissue treatment site.