Patent ID: 8912318

Claim:
A compound having a formula or a pharmaceutically acceptable salt, a hydrate, a solvate, or combinations thereof, where: R 1 is selected from aliphatic, heteroaliphatic, aryl, heteroaryl, charged moieties, or metal complexes; R 2 is selected from hydrogen, aliphatic, heteroaliphatic, aryl, heteroaryl, functional group protecting groups, oligonucleotides, a phosphorous-containing compound, a sulfur-containing compound, a nitrogen-containing compound, an oxygen-containing compound, a metal-containing compound, or a selenium-containing compound; R 3 is selected from hydrogen, oligonucleotides, a phosphorous-containing compound, a sulfur-containing compound, a nitrogen-containing compound, an oxygen-containing compound, a metal-containing compound, or a selenium-containing compound; R 4 is selected from wherein each X is independently nitrogen, carbon, or any combination thereof; Y is selected from oxygen, sulfur, or N(R 5 ) where R 5 is selected from hydrogen, aliphatic, aryl, heteroaliphatic, or heteroaryl; Z is selected from ether, thioether, hydroxyl, sulfhydryl or N(R 5 ) 2 where each R 5 is independently selected from hydrogen, aliphatic, aryl, heteroaliphatic, heteroaryl, or any combination thereof; linker is selected from aliphatic, aryl, heteroaliphatic, or heteroaryl; each Y is independently selected from oxygen, sulfur, or NR 5 where R 5 is selected from hydrogen, aliphatic, aryl, heteroaliphatic, or heteroaryl, or any combination thereof; and m+n=2 to 4.