Patent ID: 7943760

Claim:
A compound of Formula V, or a pharmaceutically acceptable salt thereof: wherein R a ═R c ═H; R b is selected from the group consisting of: hydrogen, C 1-8 alkyl, C 1-8 alkenyl, C 1-8 alkynyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl, aralkyl, and aryl, where all rings or chains optionally bear one or more substituents; R d and R d′ are independently selected from the group consisting of: H, C 1-8 alkyl, C 1-8 alkenyl, C 1-8 alkynyl, and C 3-7 cycloalkyl; R e is absent; R f and R g are independently selected from the group consisting of: —H, halogen, C 1-8 alkyl, C 1-8 alkenyl, C 1-8 alkynyl, and C 3-7 cycloalkyl; R h is H, alkyl, aryl, or aralkyl; G is O; J is carbon; D is O; X 1 is selected from the group consisting of: N and C-M; and M is independently selected from the group consisting of: —H, halogen, —CF 3 , C 1-8 alkyl, cyano, C 1-8 alkenyl, C 1-8 alkynyl, C 3-7 cycloalkyl, C 3-7 cycloalkenyl, aryl, aralkyl, heteroaryl, saturated or unsaturated C 2-6 heterocycle, —OH, saturated or unsaturated C 1-6 alkoxy, aralkoxy, aryloxy, —SH, C 1-6 thioalkyl, thioaryl, —[(CO)OR], —[(CO)NRR], amino, —N-substituted amino, and N,N-disubstituted amino; wherein each said substituent on said amino of M is independently selected from the group consisting of: C 1-8 alkyl, C 3-7 cycloalkyl, aryl, aralkyl, —[(CO)R], —[(CO)O—(C 1-8 alkyl)], and —[(CO)—NRR]; and when M is —[(CO)NRR], —[NH(CO)NRR], —[N(C 1-8 alkyl)(CO)NRR], —[N(aryl)(CO)NRR], or —[N(aralkyl)(CO)NRR], the R groups of any said —NRR unit in M are optionally taken together such that a ring of 3 to 7 members is formed, with or without heteroatoms in place of the ring-carbon units; A 2 is CH 2 , where the hydrogen on C is optionally substituted with alkyl; or A 2 is absent.