Patent ID: 8124649

Claim:
A compound of Formula (I): wherein: R 1 is selected from H, alkyl, substituted alkyl; R 2 is selected from H, alkyl, and substituted alkyl; Y 1 is O or S; Y 2 is O; each X 1 , X 2 , and X 3 is independently selected from halo, CN, CF 3 , NO 2 , alkyl, substituted alkyl, OR, and NR 2 , COR, CONR, NRCONR, and NRC(O)OR; m, n and p each independently represent 0, 1 or 2; W 1 , W 2 and W 3 are each independently C, wherein each C is substituted with H or X 3 or Ar, provided that either W 2 or W 3 is the point of attachment for Ar; Ar is a 5-10 membered aromatic or heteroaromatic group that is optionally substituted with (X 2 ) n ; A is selected from the group consisting of CH 2 Q, —O—Z, —NRZ, NR—C(O)Z, NRC(O)—OZ, NRC(O)—NRZ, NRC(O)—OZ, OC(O)NRZ, and —C(═O)NRZ, where Z is H, alkyl, substituted alkyl, heterocyclyl, substituted heterocyclyl, aryl, or substituted aryl, and Q is OZ or NRZ; R is independently selected at each occurrence from the group consisting of H, alkyl or substituted alkyl, and two R on NR 2 can cyclize to form a 5-7 membered ring that can be substituted and may optionally contain one additional heteroatom selected from N, O and S as a ring member, and R and Z, when both present on A or Q, can optionally cyclize to form a 5-7 membered ring that can be substituted and can include an additional O, N or S as a ring member; and each q is independently 0, 1 or 2; or a pharmaceutically acceptable salt thereof.