Patent ID: 7855273

Claim:
A method of manufacturing gelatin with reduced endotoxin content, wherein the molecular weight of the liposaccharide subunits of the endotoxin is about 20,000 Da, comprising processing a starting material gelatin-containing solution containing gelatin, wherein the average molecular weight of said geletan contained in said starting material gelatin-containing solution is in a range of from 30,000 to 300,000 Da, and an endotoxin with an ultrafiltration membrane having a molecular weight cut-off falling within a range of from 50,000 to 300,000 Da and having a molecular weight cut-off capable of passing at least a portion of the gelatin contained in the starting material gelatin-containing solution to obtain a permeate that is a gelatin-containing solution with a reduced endotoxin content, wherein the gelatin concentration in said starting material gelatin-containing solution is in a range of 1 to 30 weight percent.