Patent ID: 7067538

Claim:
A compound of Formula I or II: or a pharmaceutically acceptable salt of a compound of Formula I or II; wherein: D is (CH 2 ) n , where n is 0 or 1; R 1 , R 2 , R 3 , and R 4 are each independently selected from the group consisting of: H, C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl, C 3 –C 6 heterocycloalkyl, phenyl, halogen, and CF 3 ; W is N, CH, or CF; R 5 and R 6 are each independently H or F; Z is selected from the group consisting of: C 1 –C 6 alkyl, CH 2 Br, CH 2 Cl, CF 3 , CH 2 F, CHF 2 , CH 2 R 7 , CFR 7 R 8 , CF 2 R 7 , CH 2 OR 7 , CHFOR 7 , CF 2 OR 7 , C(O)NR 7 R 8 , CO 2 R 7 , phenyl, C 6 –C 12 aryl, and C 5 –C 12 heteroaryl; R 7 , R 8 , and R 9 , are independently selected from the group consisting of H, C 1 –C 6 alkyl, CF 3 , CCl 3 , C 6 –C 12 aryl, C 6 –C 12 aryl-C 1 –C 6 alkyl-, C 5 –C 12 heteroaryl, and C 5 –C 12 heteroaryl-C 1 –C 6 alkyl-; R 10 and R 12 are independently selected from the group consisting of F, H, C 1 –C 6 alkyl, CF 3 , CCl 3 , C 6 –C 12 aryl, C 6 –C 12 aryl-C 1 –C 6 alkyl-, C 5 –C 12 heteroaryl, and C 5 –C 12 heteroaryl-C 1 –C 6 alkyl-; and wherein 2-(diphenyl-methanesulfonyl)-1-pyridin-2-yl-ethanone is not included.