Patent ID: 7902240

Claim:
A compound of Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof: wherein: R 1 is selected from the group consisting of alkyl and substituted alkyl; R 2 is selected from the group consisting of hydrogen, alkyl, and substituted alkyl; R 3 is selected from the group consisting of -L 1 -A 1 , wherein L 1 is selected from the group consisting of —C(O)—, —C(S)—, and —S(O), and A 1 is selected from the group consisting of alkyl, substituted alkyl, alkoxy, substituted alkoxy, aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, and NR 8 R 9 ; R 4 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, and substituted alkynyl; or R 3 and R 4 together with the nitrogen atom bound thereto join to form a five to seven membered heterocycloalkyl or substituted heterocycloalkyl group where optionally one additional ring atom is selected from the group consisting of O, S, or NR 11 ; X is N; R 6 is selected from the group consisting of cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, all of which may be optionally substituted with —(R 10 ) m where R 10 is as defined herein, m is 1, 2, 3, or 4, and each R 10 may be the same or different when m is 2, 3, or 4; R 7 is -L 2 -A 2 wherein L 2 is C 1 -C 5 alkylene and A 2 is selected from the group consisting of aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, and substituted heterocycloalkyl, provided that R 7 is not attached to X; R 8 is selected from the group consisting of hydrogen and alkyl; R 9 is selected from the group consisting of hydrogen, hydroxy, alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, and substituted heterocycloalkyl; or R 8 and R 9 together with the nitrogen atom pendent thereto join to form a heterocycloalkyl or substituted heterocycloalkyl; R 10 is selected from the group consisting of cyano, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, —CF 3 , alkoxy, substituted alkoxy, halo, and hydroxy; and R 11 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, —SO 2 alkyl, and —SO 2 substituted alkyl.