Patent ID: 6919464

Claim:
A compound of the formulae (1A) or (2A) wherein R3 is a group having one of the following formulas (3a) through (3v) R 4 is H, OH, OR 15 , or ═O; R 5 is H or CH 3 ; R 6 and R 7 are H or combine to form a double bond or combine to form an epoxide group; R 8 in formula (1) is trans-1-butenyl, 1,3-butadienyl, n-butyl, 3-hydroxy-1-butenyl, n-propyl, 1-propenyl, 1,2-epoxy-2-butyl, 3-oxo-1-butenyl, CH 3 CH(OCH 3 )CH═CH—, CH 3 CH(OR 15 )CH═CH—, CH 3 CH═CHCH(CH 2 CO 2 Me)—, or CH 3 CH═CHCH(CH 2 CON(Me 2 ))— R 9 is H or a group having one of the following formulas (9a) through (9p): R 15 is C2-C6 alkyl, C3-C6 branched alkyl, C3-C7 cycloalkyl, C1-C6 alkoxy-C1-C6 alkyl, C1-C6 alkylthio-C1-C6 alkyl, halo C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, formyl, C1-C6 alkylcarbonyl, or C3-C6 branched alkylcarbonyl, C3-C7-cycloalkylcarbonyl, C1-C6 alkoxy-C1-C6 alkylcarbonyl, halo C1-C6 alkylcarbonyl, C2-C6 alkenylcarbonyl, C2-C6 alkynylcarbonyl; R 16 in formula (9m) is C1-C6 alkyl, C1-C6 alkenyl, formyl, C1-C6 alkylcarbonyl, or C3-C6 branched alkylcarbonyl; n in formula (9n) is an integer from 1 to 4; provided that at least one of the following conditions is satisfied: a) R 3 is selected from the group consisting of formulas (3g) to (3v); b) R 4 is —OCH 3 , —OR 15 or ═O; c) R 6 and R 7 are H or R 6 and R 7 combine to form an epoxide group; d) R 8 is propyl, 1,2-epoxy-1-butyl, CH 3 C(O)CH═CH—, CH 3 CH(OCH 3 )CH═CH—, CH 3 CH(OR 15 )CH═CH—, CH 3 CH═CHCH(CH 2 CO 2 Me)—, or CH 3 CH═CHCH(CH 2 CON(Me 2 ))— e) R 9 is selected from the group consisting of formulas (9j) through (9p); and provided further that the compound 22,23-dihydro-rham-I is excluded.