Patent ID: 7385063

Claim:
A method for preparing a compound represented by one of structural formulae XIIIa and XIIIb, comprising: forming a compound represented by structural formula XI by treating an aniline derivative represented by structural formula III with R 7 CN in the presence of (1) a Lewis acid at elevated temperature or (2) a strong base; and forming the compound represented by one of structural formulae XIIIa and XIIIb by treating the compound represented by structural formula XI with an α-haloketone or an α-haloaldehyde in a solvent, wherein R 7 , R 8 , and R 9 , are independently hydrogen, alkyl, aryl, heterocyclyl, nitro, cyano, carboxylic acid, ester, amide, halo, hydroxyl, amino, substituted amino, alkoxy, acyl, ureido, sulfonamido, sulfamido, sulfonyl, sulfinyl, or guanadinyl.