Patent ID: 8615369

Claim:
A method of improving the resolution of compounds eluted from a chromatography device comprising: (a) measuring spectroscopic data from an effluent eluted from a chromatography device as a function of elution time, the effluent containing eluted compounds; (b) identifying at least some peaks in intensity as a function of time in at least some of the measured spectroscopic data to form a first set of identified peaks; (c) discarding from the first set of identified peaks those peaks that are not due to an eluted compound thereby forming a second set of peaks from those retained; (d) transforming each peak in the second set of peaks into a first model peak centered on the elution time of each peak in the second set of peaks; (e) adding together some or all the model peaks created in step (d) to create a new chromatogram; (f) identifying at least some peaks in intensity in the new chromatogram; (g) grouping together all identified peaks in intensity in the second set of peaks having elution times within a given time period of identified peaks in intensity in the new chromatogram and assigning them to a single eluted compound thereby forming a processed data set; wherein steps (b)-(g) are performed by at least one of: (i) a computer running computer software or (ii) a dedicated electronic processor.