Patent ID: 7989454

Claim:
A compound of formula (I): wherein: R 1 is phenyl, unsubstituted or mono- or bi-substituted with alkoxy, halogen, hydroxy, lower alkyl, amino or amino-lower alkyl, heteroaryl, unsubstituted or substituted with lower alkyl or halogen, benzo[1,3]dioxole, unsubstituted or substituted with lower alkyl, dihydro-benzo[1,4]dioxine, unsubstituted or substituted with lower alkyl, benzo[b][1,4]dioxepine, unsubstituted or substituted with lower alkyl, dihydro-benzofuran, unsubstituted or substituted with lower alkyl, or benzo[1,4]oxazin, unsubstituted or substituted with lower alkyl; R 2 and R 3 , independently of each other, are: hydrogen, lower alkyl, cycloalkyl, phenyl, lower alkyl-cycloalkyl, lower alkyl-heteroaryl, lower alkyl-alkoxy, alkoxy-lower alkyl, lower alkyl-heterocycloalkyl, unsubstituted or substituted with lower alkyl, C(O)-amino, lower alkyl-phenyl, said phenyl being unsubstituted or mono- or bi-substituted with lower alkyl, halogen, alkoxy or O-haloloweralkyl, benzo[1,3]dioxole, unsubstituted or substituted with lower alkyl, dihydro-benzo[1,4]dioxine, unsubstituted or substituted with lower alkyl, benzo[b][1,4]dioxepine, unsubstituted or substituted with lower alkyl, benzofuran, unsubstituted or substituted with lower alkyl, benzo[1,4]oxazin, unsubstituted or substituted with lower alkyl, CH 2 -benzo[1,3]dioxole, unsubstituted or substituted with lower alkyl, CH 2 -dihydro-benzo[1,4]dioxine, unsubstituted or substituted with lower alkyl, CH 2 -benzo[b][1,4]dioxepine, unsubstituted or substituted with lower alkyl, CH 2 -benzofuran, unsubstituted or substituted with lower alkyl CH 2 -benzo[1,4]oxazin, unsubstituted or substituted with lower alkyl, or R 2 and R 3 , together with the nitrogen atom to which they are attached, form a heterocycloalkyl ring, optionally having a second heteroatom from N, O or S, said heterocycloalkyl ring being unsubstituted or mono- or bi-substituted with halogen, lower alkyl, carbonyl, C(═O) or hydroxy; X is O or C; and “a” is a single bond or an alkynyl bond, and pharmaceutically acceptable salts thereof.