Patent ID: 8710203

Claim:
An isolated nucleic acid molecule comprising: (a) nucleotide sequences encoding human heavy chain framework regions, a nucleotide sequence encoding a human heavy chain CDR1 region comprising SEQ ID NO: 61, a nucleotide sequence encoding a human heavy chain CDR2 region comprising SEQ ID NO: 64, and a nucleotide sequence encoding a human heavy chain CDR3 region comprising SEQ ID NO: 67; and nucleotide sequences encoding human light chain framework regions, a nucleotide sequence encoding a human light chain CDR1 region comprising SEQ ID NO: 70, a nucleotide sequence encoding a human light chain CDR2 region comprising SEQ ID NO: 72, and a nucleotide sequence encoding a human light chain CDR3 region comprising SEQ ID NO: 74; or (b) nucleotide sequences encoding human heavy chain framework regions, a nucleotide sequence encoding a human heavy chain CDR1 region comprising SEQ ID NO: 62, a nucleotide sequence encoding a human heavy chain CDR2 region comprising SEQ ID NO: 65, and a nucleotide sequence encoding a human heavy chain CDR3 region comprising SEQ ID NO: 68; and nucleotide sequences encoding human light chain framework regions, a nucleotide sequence encoding a human light chain CDR1 region comprising SEQ ID NO: 70, a nucleotide sequence encoding a human light chain CDR2 region comprising SEQ ID NO: 72, and a nucleotide sequence encoding a human light chain CDR3 region comprising SEQ ID NO: 74.