Patent ID: 8545441

Claim:
In combination with a device, comprising a disposable injector ( 4 ) having a sterile and gastight cylinder-piston unit ( 100 ), which has a first chamber ( 105 ), a container adapter ( 200 ) mounted on the disposable injector ( 4 ), and a container ( 250 ) releasably fitted on the container adapter ( 200 ) and having a second chamber ( 255 ), or a cylinder-piston unit ( 254 ) with a second chamber ( 255 ), the cylinder-piston unit ( 254 ) releasably fitted on the container adapter ( 200 ), the second chamber ( 255 ) is at least temporarily closed in a sterile and gastight manner by means of a stopper ( 257 ), the container adapter ( 200 ) comprises a connecting tube ( 242 ) having a lateral surface ( 247 ), the connecting tube ( 242 ) having a longitudinal bore ( 244 ) initially closed by means of a cap ( 290 ) and having at least one tubular channel ( 245 ) connecting the longitudinal bore ( 244 ) to the lateral surface ( 247 ), the improvement which comprises: the cap ( 290 ) includes a detachable cap base ( 294 ), the cap base ( 294 ) is initially surrounded on its inner side by a groove ( 293 ); the stopper ( 257 ) having a lateral surface ( 277 ), the stopper ( 257 ) at the top thereof has on its underside oriented toward the second chamber ( 255 ) a central recess ( 271 ), the stopper at the top thereof includes a recess base ( 274 ) that initially lies above and aligned with the central recess ( 271 ), the recess base ( 274 ) is initially bounded on the upper side of the top of the stopper ( 257 ) by a surrounding annular groove ( 273 ), the stopper ( 257 ) below the top thereof has therein at least one stopper channel ( 275 ) connecting the lateral surface ( 277 ) of the stopper ( 257 ) to the central recess ( 271 ), the at least one stopper channel ( 275 ) having a channel base ( 278 ) nearest the top of the stopper ( 257 ), the central recess ( 271 ) is sized to receive and to hold the cap base ( 294 ) and recess base ( 274 ), both the cap base ( 294 ) and the recess base ( 274 ) are moved within the central recess ( 271 ) by means of the connecting tube ( 242 ) when the container ( 250 ) or the cylinder-piston unit ( 254 ) is pushed in or activated and the cap base ( 294 ) and the recess base ( 274 ) are held by the stopper ( 257 ) in predetermined position after activation, after the container ( 250 ) has been pushed in or activated, the connecting tube ( 242 ) connects the interior ( 110 ) of the cylinder-piston unit ( 100 ) to the interior ( 252 ) of the container ( 250 ) or the cylinder-piston unit ( 254 ) by way of the at least one stopper channel ( 275 ) and the tubular channel ( 245 ).