Patent ID: 7214693

Claim:
A selective androgen receptor modulator (SARM) compound represented by the structure of formula I: wherein X is a bond, O, CH 2 , NH, Se, PR, NO or NR; G is O or S; R1 is CH 3 , CH 2 F, CHF 2 , CF 3 , CH 2 CH 3 , or CF 2 CF 3 ; T is OH, OR, NHCOCH 3 , or NHCOR; R is alkyl, haloalkyl, dihaloalkyl, trihaloalkyl, CH 2 F, CHF 2 , CF 3 , CF 2 CF 3 , aryl, phenyl, F, Cl, Br, I, alkenyl or OH; A is a ring selected from: B is a ring selected from: wherein A and B cannot simultaneously be a benzene ring; Z is NO 2 ,CN, COOH, COR, NHCOR or CONHR; Y is CF 3 , F, I, Br, Cl, CN, C(R) 3 or Sn(R) 3 ; Q 1 and Q 2 are independently of each other a hydrogen, alkyl, F, Cl, Br, I, CF 3 , CN C(R) 3 , Sn(R) 3 , N(R) 2 , NHCOCH 3 , NHCOCF 3 , NHCOR, NHCONHR, NHCOOR, OCONHR, CONHR, NHCSCH 3 , NHCSCF 3 , NHCSR, NHSO 2 CH 3 , NHSO 2 R, OR, COR, OCOR, OSO 2 R, SO 2 R, SR, Q 3 and Q 4 are independently of each other a hydrogen, alkyl, F, Cl, Br, I, CF 3 , CN, C(R) 3 , Sn(R) 3 , N(R) 2 , NHCOCH 3 , NHCOCF 3 , NHCOR, NHCONHR, NHCOOR, OCONHR, CONHR, NHCSCH 3 , NHCSCF 3 , NHCSR, NHSO 2 CH 3 , NHSO 2 R, OR, COR, OCOR, OSO 2 R, SO 2 R or SR; W 1 is O, NH, NR, NO or S; and W 2 is N or NO.