Patent ID: 7022489

Claim:
A process for preparing a composition which comprises identifying a chemical compound which specifically binds to a human or rat GALR3 receptor, recovering the chemical compound free of any receptor, and then admixing a carrier and the chemical compound, wherein the chemical compound is identified by a process which comprises: (a) contacting cells transfected with DNA or injected with RNA encoding and expressing on their cell surface the human or rat GALR3 receptor or a membrane fraction from such cells, with the compound under conditions suitable for binding, and (b) detecting specific binding of the chemical compound to the human or rat GALR3 receptor; wherein such cells prior to being transfected with such DNA do not express the human or rat GALR3 receptor, and wherein the human GALR3 receptor has an amino acid sequence identical to the amino acid sequence shown in FIG. 4 (SEQ ID NO: 4) or that encoded by plasmid pEXJ-hGalR3 (ATCC Accession No. 97827); and the rat GALR3 receptor has an amino acid sequence identical to the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2) or that encoded by plasmid pEXJ-RGalR3T (ATCC Accession No. 97826) or plasmid K1086 (ATCC Accession No. 97747).