Patent ID: 8258100

Claim:
A method for killing or inhibiting the growth of a gonadotropin-releasing hormone, lamprey III luteinizing hormone releasing hormone (1-LHRH-III), β-subunit of luteinizing hormone (bLH), estrogen, testosterone, luteinizing hormone, chorionic gonadatropin, follicle stimulating hormone, melanocyte stimulating hormone, estradiol, dopamine, or somatostatin receptor expressing prostate, breast, ovarian, pituitary or endometrial tumor cell in a mammal, comprising administering to the mammal an effective amount of a gonadotropin-releasing hormone, 1-LHRH-III, bLH, estrogen, testosterone, luteinizing hormone, chorionic gonadatropin, follicle stimulating hormone, melanocyte stimulating hormone, estradiol, dopamine, somatostatin, or an analog of these hormones that binds to the receptor expressing prostate, breast, ovarian, pituitary or endometrial tumor cell, and an effective amount of a lytic peptide, wherein said ligand is linked to said lytic peptide, and wherein said lytic peptide consists of 10 to 39 amino acid residues, is basic, and forms an amphipathic alpha helix.