Patent ID: 8273403

Claim:
A method of forming a library of surface coating synthons of formula B-S-F on a substrate, the method comprising: a) providing a substrate; b) applying compound B to the substrate thereby enabling compound B to attach to the substrate, wherein compound B is a copolymer of passive constituent P and active constituent A; c) applying compound S to the substrate thereby enabling compound S to attach to constituent A of compound B, wherein compound S is a spacer unit; and d) applying compound F to the substrate thereby enabling compound F to attach to spacer unit S, wherein compound F is a compound in the form of a biological or chemical functional group; wherein steps a) to d) result in the formation of a synthon of formula B-S-F on the substrate, and wherein steps b) to d) are performed such that each synthon formed on the substrate differs from other synthons on the substrate by having a combination selected from the group consisting of: a combination of constituent P and constituent A that is not found in other synthons on the substrate; a combination of constituent P and compound S that is not found in other synthons on the substrate; a combination of compound S and constituent A that is not found on other synthons on the substrate; a combination of compound F and constituent P that is not found in other synthons on the substrate; a combination of compound F and constituent A that is not found in other synthons on the substrate; and a combination of compound F and constituent S that is not found in other synthons on the substrate, thereby forming a library of surface coating synthons of formula B-S-F on the substrate.