Patent ID: 7326712

Claim:
A compound having a structure selected from (II) or (III): or a steroisomer, prodrug or pharmaceutically acceptable salt thereof, wherein X is NH, S or O; Z is CH or N; R 1 and R 2 are the same or different and are independently hydrogen, hydroxyl, halo, —CN, —NO 2 , —NH 2 , —R, —OR, —SCH 3 , —CF 3 , —C(═O)OR or —OC(═O)R, where R is alkyl or substituted alkyl; R 3 is hydrogen, —NH 2 , alkyl, —CN, or —NO 2 ; L 1 is a direct bond, —NR′—, —OC(═S)NH— or —NHC(═S)O—, wherein R′ is H or alkyl; Cycl 1 is selected from: L 2 is —C(═S)NH—, —NHC(═S)—, —NHC(═S)NH—, —C(═O)NH—, —NHC(═O)—, —NHC(═O)NH—, —NH(CH 2 ) n —, —(CH 2 ) n NH—, —NH(CH 2 ) n NH—, —C (═S)NH(CH 2 ) n —, —NHC(═S)(CH 2 ) n —, —(CH 2 ) n C(═S)NH(CH 2 ) n —, —(CH 2 ) n NHC(═S)(CH 2 ) n —, —S(═O) 2 —, —S(═O) 2 NH—, —NHS(═O) 2 —, —NHC(═S)NHCH 2 —, —NH—, or —C(═S)—, wherein n is, at each occurrence the same or different and independently 1, 2, 3 or 4; and Cycl 2 is selected from: