Patent ID: 8889184

Claim:
A pharmaceutical composition for oral administration comprising at least one particle containing an active ingredient, said at least one particle comprising: a) a core which contains the active ingredient of the particle and, optionally, suitable adjuvants, and b) one or more coating layers applied to the core, such that either a single coating layer, when only one coating layer is present, or an outermost coating layer, when more than one coating layer is present, contains: (i) at least one polymer capable of forming a gel with water, (ii) at least one polymer not capable of forming a gel with water, wherein said polymer is substantially insoluble in water at a pH of 7.0 and soluble at or below a pH of 3.5, (iii) at least one compound capable of releasing carbon dioxide, and (iv) optionally, additional adjuvants, wherein at least one of the polymers set forth in b)(i) and b)(ii) is an acidic polymer or the single coating layer or outermost coating layer includes an acidic compound, further wherein the weight ratio between the polymer set forth in b) (ii) and the polymer set forth in b) (i) ranges from 3:1 to 1:5.