Patent ID: 7161006

Claim:
A compound of formula I: where n is 2, 3 or 4; Ar 1 represents phenyl or heteroaryl, either of which bears 0–3 substituents independently selected from halogen, CN, NO 2 , CF 3 , CHF 2 , OH, OCF 3 , C 1-4 alkoxy or C 1-4 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; Ar 2 represents phenyl or heteroaryl, either of which bears 0–3 substituents independently selected from halogen, CN, NO 2 , CF 3 , CHF 2 , OH, OCF 3 , C 1-4 alkoxy or C 1-4 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; R 1 represents C 1-4 alkyl, or together with R 2 completes a pyrrolidine, piperidine or homopiperidine ring; R 2 represents H or C 1-6 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; or together with R 1 completes a pyrrolidine, piperidine or homopiperidine ring; or together with R 3 completes a tetrahydroisothiazole-1,1-dioxide ring; and R 3 represents phenyl, naphthyl or heteroaryl, any of which may bear up to 3 substituents selected from halogen, CN, NO 2 , CF 3 , CHF 2 , OH, OCF 3 , C 1-4 alkoxy, C 1-4 alkoxycarbonyl, C 2-6 acyl, C 2-6 acyloxy, C 2-6 acylamino, amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino or C 1-4 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; or R 3 represents CF 3 or a non-aromatic hydrocarbon group of up to 6 carbon atoms optionally bearing one substituent selected from halogen, CN, CF 3 , OH, OCF 3 , C 1-4 alkoxy, C 1-4 alkoxycarbonyl, C 2-6 acyl, C 2-6 acyloxy, C 2-6 acylamino, amino, C 1-6 alkylamino, di(C 1-4 alkyl)amino or phenyl, naphthyl or heteroaryl, any of which may bear up to 3 substituents selected from halogen, CN, NO 2 , CF 3 , CHF 2 , OH, OCF 3 , C 1-4 alkoxy, C 1-4 alkoxycarbonyl, C 2-6 acyl, C 2-6 acyloxy, C 2-6 acylamino, amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino or C 1-4 alkyl which op bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; or R 3 together with R 2 completes a tetrahydroisothiazole-1,1-dioxide ring; or a pharmaceutically acceptable salt thereof.