Patent ID: 8630703

Claim:
A method of enhancing a cytotoxicity of an imidazoacridinone chemotherapeutic agent towards cells in a region that comprises a tumor in a body of a subject in need thereof, the method comprising administering to the subject said imidazoacridinone chemotherapeutic agent and illuminating said region, wherein said imidazoacridinone chemotherapeutic agent is a hydrophobic weak base and acts as a photosensitizer when exposed to illumination at a wavelength in a range of from 400 to 800 nm, wherein said imidazoacridinone chemotherapeutic agent is selected from the group consisting of C-1330, C-1375, C-1379 and C-1311 and wherein said imidazoacridinone chemotherapeutic agent and a wavelength of said illumination are selected such that said chemotherapeutic agent acts as a therapeutically effective photosensitizer when exposed to said illumination.