Patent ID: 8530486

Claim:
A compound of the formula Wherein X is N; Y is CR 3 ; R′ is NR x R y wherein R x and R y are each H, C 1 -C 6 alkyl or phenyl, wherein phenyl is optionally substituted with halogen, or NR x R y is a heterocyclic group that contains up to 6 C atoms and up to 3 heteroatoms selected from N, O, and S, which is saturated or partially or wholly unsaturated; wherein R 3 , R 4 , R 5 and R 6 are independently selected from H, F, Cl, Br, I, C 1-4 alkyl, C 2-5 alkenyl, C 2-5 alkynyl, C 1-4 alkoxy, C 1-4 alkylthio, C 3-6 cycloalkyl, O—C 3-6 cycloalkyl, phenyl, benzyl, O-phenyl, NH-phenyl, S-phenyl, O—C 1-4 alkyl-phenyl, C 1-4 alkyl-phenyl, CF 3 , O—CF 3 , S—CF 3 , hydroxy, nitro, cyano, O—C 1-4 alkyl-N(CH 3 ) 2 , and NR a R b , wherein R a and R b are independently selected from H, C 1-4 alkyl, phenyl, benzyl and phenethyl, and wherein any phenyl, alkyl or cycloalkyl moiety is optionally substituted with 1 to 3 substituents selected from C 1-3 alkyl, halogen, hydroxy, amino and C 1-3 alkoxy; wherein R 7 is selected from 4-7 membered heterocyclyl, C 3-7 cycloalkyl 4-7 membered heterocyclyl and bis-(4-7 membered heterocyclyl), and is optionally substituted with 1 to 3 substituents selected from C 1-3 alkyl, halogen, hydroxy, amino and C 1-3 alkoxy; or a pharmaceutically acceptable salt, ester or solvate thereof.