Patent ID: 8461145

Claim:
A compound of formula (I) or any stereochemically isomeric form thereof wherein A is CH 2 , CO, or O; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are each independently selected from hydrogen, halo, hydroxy, C 1-6 alkyl, polyhaloC 1-6 alkyl, C 3-6 cycloalkyl, C 1-6 alkyloxy, polyhaloC 1-6 alkyloxy, COOR 9 or CONR 10 R 11 ; wherein R 9 , R 10 and R 11 are each independently selected from hydrogen, C 1 - 6 alkyl, C 1-4 alkyloxyC 1-4 alkyl, polyhaloC 1-6 alkyl, polyhaloC 1-4 alkyloxyC 1-4 alkyl, C 3-6 cycloalkyl, C 3-6 cycloalkylC 1-4 alkyl, aminoC 2-5 alky, mono- or (diC 1-4 alkyl)aminoC 2-5 alkyl; and wherein NR 10 R 11 may form a heterocyclic ring selected from pyrrolidine, piperidine, morpholine, piperazine, or piperazine substituted with C 1-4 alkyl; provided that at least one of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 is defined as COOR 9 or CONR 10 R 11 ; and provided that when radical A represents O then the substituents R 5 , R 6 , R 7 and R 8 are not COOR 9 ; or a pharmaceutically acceptable salt thereof, or an N-oxide thereof.