Patent ID: 7029862

Claim:
A method of detecting or identifying an agent which binds a mammalian CXC Chemokine Receptor 3 (CXCR3) protein or ligand binding variant thereof, comprising combining an agent to be tested and a composition comprising an isolated and/or recombinant mammalian CXCR3 protein or ligand binding variant thereof under conditions suitable for binding of ligand to said mammalian CXCR3 protein or ligand binding variant, and detecting or measuring the formation of a complex between said agent and said mammalian CXCR3 protein or ligand binding variant, wherein said mammalian CXCR3 protein or ligand binding variant selectively binds at least one chemokine selected from the group consisting of IP-10 and Mig, and shares at least 90 amino acid sequence identity with SEQ ID NO:2.