Patent ID: 7122571

Claim:
A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound of formula I wherein: Q 1 is selected from the group consisting of hydrogen, trifluoromethyl, (C 1 –C 8 )alkyl, substituted and unsubstituted aryl, and substituted and unsubstituted heteroaryl; Q 2 is selected from the group consisting of hydrogen, trifluoromethyl, (C 1 –C 8 )alkyl, substituted and unsubstituted aryl, substituted and unsubstituted heteroaryl, substituted and unsubstituted aryl(C 1 –C 3 )alkyl, and substituted and unsubstituted heteroaryl(C 1 –C 3 )alkyl; n is zero or one; m is zero, one, two or three; X is selected from the group consisting of hydrogen and hydroxymethyl; and Y is selected from the group consisting of hydrogen, (C 1 –C 8 )alkyl, (C 1 C 8 )alkoxy, nitro, amino, sulfamyl and (C 1 –C 3 )alkylsulfonyl; provided: (i) Q 1 and Q 2 may not both be hydrogen in the same compound; (ii) Q 1 and Q 2 may not both be (C 1 –C 8 )alkyl in the same compound; (iii) when n is zero, Y must be sulfamyl or (C 1 –C 3 )alkylsulfonyl; (iv) when m and n are both zero and Q 2 is —H or (C 1 –C 8 )alkyl, then Q 1 may not be phenyl, unless substituted at the 4-position by other than hydroxy, alkyl, alkoxy or alkoxyalkyl; and (v) when n is one, Q 2 must be trifluoromethyl; or a pharmaceutically acceptable salt thereof.