Patent ID: 7419996

Claim:
A pharmaceutical composition, comprising: a) a benzimidazole derivative having the formula: wherein R 3 is selected from the group consisting of H, carboxyl (—CO 2 H), hydroxyl, amino, chloro, difluormethoxy, benzoyl, phenyl-thio, pyridinyl, propyl-thio, diphenyl, 5-methoxy, fluorophenylmethyl-2-chloro, propenyl, chloropropyl or esters (—CO 2 R 4 ) wherein R 4 is selected from the group consisting of alkoxy, haloalkyl, alkenyl, and cycloalkyl, wherein the alkyl groups have from 1-8 carbons, or CH 3 CH 2 (OCH 2 CH 2 )n-, or CH 3 CH 2 CH 2 (OCH 2 CH 2 CH 2 )n-, or (CH 3 ) 2 CH(OCH(CH 3 )CH 2 )n-, wherein n is from 1-3 wherein R 1 is OH, Cl, SH, carbamate or piperidin-4-yl, and R 2 is hydrogen, α-methylvinyl, 3-chloropropyl or piperidin-4-yl, or the pharmaceutically effective organic or inorganic salts thereof, or mixtures thereof; b) PEG 400; c) a dipolar aprotic solvent; and d) water, wherein the ratio of PEG 400:dipolar aprotic solvent:water by weight is 3:1:1 or 7:1:2.