Patent ID: 6852751

Claim:
A compound having a structure according to formula (I): wherein: (A) A is selected from a covalent bond, C 1 -C 3 alkyl, O, S, SO, and SO 2 ; (B) R 1 is selected from hydrogen, alkoxy, halogen, —CN, alkyl, alkene, alkyne, haloalkyl, aryl, arylalkyl, cycloalkyl, and cycloalkylalkyl; (C) X is selected from a covalent bond and C 1 -C 3 alkyl optionally substituted with a hydroxy group; (D) Y is selected from a covalent bond; (E) Z is selected from 3-indolyl; and (F) G is selected from —S—, —O—, —N(R 3 )— and —CH═CH—, where R 3 is selected from hydrogen, alkyl, and acyl; or an optical isomer, diasteromer or enantiomer for Formula (I), or a pharmaceutically-acceptable salt, or biohydrolyzable ester thereof or conjugates thereof.