Patent ID: 7238785

Claim:
A humanized RS7 antibody or fragment thereof that binds to an EGP-1 glycoprotein, wherein the complementarity determining regions (CDRs) of the light chain variable region of the humanized RS7 antibody or fragment thereof comprise CDR1 comprising the amino acid sequence of KASQDVSIAVA (SEQ ID NO:28); CDR2 comprising the amino acid sequence of SASYRYT (SEQ ID NO:29); and CDR3 comprising the amino acid sequence of QQHYITPLT (SEQ ID NO:30) and wherein the CDRs of the heavy chain variable region of the humanized RS7 antibody or fragment thereof comprise CDR1 comprising the amino acid sequence of NYGMN (SEQ ID NO:31); CDR2 comprising the amino acid sequence of WINTYTGEPTYTDDFKG (SEQ ID NO:32) and CDR3 comprising the amino acid sequence of GGFGSSYWYFDV (SEQ ID NO:33).