Patent ID: 8853423

Claim:
A compound of Formula (VI), or a pharmaceutically acceptable salt, or solvate thereof: wherein, R 1 is H, F, C 1 -C 6 alkyl, or C 1 -C 6 fluoroalkyl; is azetidinyl or pyrrolidinyl; each R 4 is independently selected from F, Cl, —OH, —CH 3 , —CF 3 , —OCF 3 and —OCH 3 ; each R 5 is independently selected from halogen, —CN, —OH, —OR 7 , substituted or unsubstituted C 1 -C 6 alkyl, and substituted or unsubstituted C 1 -C 6 fluoroalkyl; each R 6 is independently selected from halogen, —CN, —OH, —OR 7 , —SR 7 , —S(═O)R 8 , —S(═O) 2 R 8 , —NHS(═O) 2 R 8 , substituted or unsubstituted C 1 -C 6 alkyl, and substituted or unsubstituted C 1 -C 6 fluoroalkyl; each R 7 is independently selected from H, —C(═O)R 8 , —C(═O)OR 8 , —C(═O)NHR 8 , C 1 -C 6 alkyl, C 1 -C 6 heteroalkyl, or C 1 -C 6 fluoroalkyl; R 8 is independently selected from C 1 -C 6 alkyl, C 1 -C 6 heteroalkyl, or C 1 -C 6 fluoroalkyl; each R 9 is independently selected from F, Cl, —OH, C 1 -C 4 alkyl, C 1 -C 4 fluoroalkyl, C 1 -C 4 fluoroalkoxy, C 1 -C 4 alkoxy, and C 1 -C 4 heteroalkyl; each R 10 is independently H, F, or C 1 -C 4 alkyl; or both R 10 are taken together with the carbon atom to which they are attached to form —C(═O)—; X is —O—; m is 0, or 1; n is 0, 1, or 2; p is 0, 1, 2, or 3; t is 1, or 2; wherein substituted groups are substituted with one or more groups selected from halogen, —CN, —NH 2 , —OH, —NH(CH 3 ), —N(CH 3 ) 2 , —CH 3 , —CH 2 CH 3 , —CF 3 , —OCH 3 , and —OCF 3 .