Patent ID: 6846637

Claim:
A method of obtaining one or more human antibody molecules containing a binding site that binds human Fas, the method comprising bringing into contact a population of human antibody molecules and a peptide of 10-20 amino acids in length which is a fragment of human Fas, said fragment comprising an amino acid sequence selected from the group consisting of: (i) GQFCHKPCPPGERKARDCTV (SEQ ID NO. 1), (ii) QEGKEYTDKAHFSSKCRRCR (SEQ ID NO. 2), (iii) HFSSKCRRCRLCDEGHGLEV (SEQ ID NO. 3), (iv) EINCTRTQNTKCRCKPNFFC (SEQ ID NO. 4), (v) KCRCKPNFFCNSTVCEHCDP (SEQ ID NO. 5), (vi) WLCLLLLPIPLIVWVKRKEV (SEQ ID NO. 6), (vii) LIVWVKRKEVQKTCRKHRKE (SEQ ID NO. 7), and (viii) QKTCRKHRKE (SEQ ID NO. 9); said fragment comprising an immunogenic amino acid sequence which is found within an amino acid sequence selected from said group; and selecting one or more human antibody molecules able to bind said peptide.