Patent ID: 8003677

Claim:
A compound of formula I, wherein: R is hydrogen, (C 1 -C 16 )-alkyl, (C 1 -C 5 )-alkyloxy, (C 1 -C 5 )-alkylthio, (C 1 -C 5 )-alkylamino, di-(C 2 -C 8 -alkylamino, (C 0 -C 4 )-alkylene-(C 6 -C 10 )-aryl, (C 0 -C 4 )-alkylene-(C 5 -C 12 )-heteroaryl, (C 0 -C 4 )-alkylene-(C 3 -C 12 )-heterocyclyl, (C 0 -C 4 )-alkylene-(C 3 -C 12 )-cycloalkyl, or a bicyclic (C 8 -C 14 ) ring system, wherein the aryl, heteroaryl, heterocyclyl, cycloalkyl or bicyclic (C 8 -C 14 ) ring system may be mono- or polysubstituted by halogen, (C 1 -C 6 )-alkyl, (C 1 -C 3 )-alkyloxy, hydroxyl, (C 1 -C 6 )-alkylmercapto, amino, (C 1 -C 6 )-alkylamino, di-(C 2 -C 12 )-alkylamino, mono-(C 1 -C 6 -alkylaminocarbonyl, di-(C 2 -C 6 -alkylaminocarbonyl, (C 1 -C 6 )-alkoxycarbonyl, (C 1 -C 6 -alkylcarbonyl, cyano, trifluoromethyl, trifluoromethyloxy, (C 1 -C 6 )-alkylsulfonyl or aminosulfonyl; R1 is hydrogen, (C 1 -C 10 )-alkyl, (C 1 -C 10 )-alkyloxy, amino, mono-(C 1 -C 10 )-alkylamino, or di-(C 2 -C 12 )-alkylamino, wherein the alkyl may be substituted by halogen, (C 1 -C 6 )-alkyl, (C 1 -C 3 )-alkyloxy, hydroxyl, (C 1 -C 6 )-alkylmercapto, amino, (C 1 -C 6 )-alkylamino, di-(C 2 -C 12 )-alkylamino, -(C 6 -C 10 )-aryl, —(C 5 -C 12 )-heteroaryl, —(C 3 -C 12 )-heterocyclyl or —(C 3 -C 12 )-cycloalkyl, wherein the aryl, heteroaryl, heterocyclyl or cycloalkyl may be mono- or polysubstituted by halogen, (C 1 -C 6 )-alkyl, (C 1 -C 3 )-alkyloxy, hydroxyl, (C 1 -C 6 )-alkylmercapto, amino, (C 1 -C 6 )-alkylamino, or di-(C 2 -C 12 )-alkylamino; R2 is hydrogen, (C 1 -C 16 )-alkyl, or (C 0 -C 4 )-alkylene-(C 6 -C 10 )-aryl; R3 is hydrogen, (C 1 -C 6 )-alkyl, (C 1 -C 3 )-alkyloxy, hydroxyl, (C 1 -C 6 )-alkylmercapto, amino, (C 1 -C 6 )-alkylamino, di-(C 2 -C 12 )-alkylamino, cyano, (C 1 -C 6 )-alkylcarbonyl, halogen, trifluoromethyl, trifluoromethyloxy, (C 1 -C 6 )-alkylsulfonyl, or aminosulfonyl; A is S; B is C(R3); D is N; n is 1; L is a bond, —C(═O)—, —C(═S)—, —C(═O)—N(R2)—, —C(═O)—O—, —S(O) 0-2 —, —S(O) 0-2 —N(R2)—, or a mono- or bicyclic ring system in which one or more ring members may be N(R3), O, S or —C(═O)—; and M is —C(═O)—N(R2)—, —N(R2)—C(═O)—, —S(O) 0-2 —, —S(O) 0-2 —N(R2)—, —N(R2)—S(O)—O—, or —O—C(═)—; or a physiologically compatible salt thereof.