Patent ID: 8211645

Claim:
A composition comprising a first oligonucleotide probe comprising a sequence that hybridizes to a 5′ portion of a chimeric DNA or chimeric mRNA from a transcriptional regulatory region of an androgen regulated gene, wherein the androgen regulated gene is selected from the group consisting of TMPRSS2 and PSA, and a second oligonucleotide probe comprising a sequence that hybridizes to a 3′ portion of the chimeric DNA or chimeric mRNA from an ETS family member gene, wherein the ETS family member gene is selected from the group consisting of ERG, ETV1 (ER81), FLI1, ETS1, ETS2, ELK1, ETV6 (TEL1), ETV7 (TEL2), GABPα, ELF1, ETV4 (E1AF; PEA3), ETV5 (ERM), ERF, PEA3/E1AF, PU.1, ESE1/ESX, SAP1 (ELK4), ETV3 (METS), EWS/FLI1, ESE1, ESE2 (ELF5), ESE3, PDEF, NET (ELK3; SAP2), NERF (ELF2), and FEV.