Patent ID: 7790373

Claim:
A set of materials comprising two separate compositions of matter, wherein: a) the first composition of matter is a sample comprising an analyte and an undesired constituent, wherein the analyte is a polynucleotide, and the undesired constituent is selected from a nucleotide, an anionic detergent or a chelator; and b) the second composition of matter is a material comprising a composition comprising a solid phase that is coated with polynucleotides at least 20 nucleotides in length, wherein: i) the solid phase can bind both the undesired constituent and the analyte; ii) the polynucleotide coating covers the exposed surface of the solid phase to an extent that any binding of the solid phase to the analyte is impeded; iii) said polynucleotides are attached to said solid phase ionic interactions; and iv) the sample and the second material are not in contact with each other.