Patent ID: 8828385

Claim:
A method for treating or inhibiting a cell proliferative disease or disorder associated with the expression of human fibroblast growth factor receptor 3 (FGFR3), comprising administering a therapeutically effective amount of a pharmaceutical composition to a subject in need thereof, wherein the pharmaceutical composition comprises as an active ingredient at least one molecule that is an antigen-binding portion of an antibody which binds to fibroblast growth factor receptor (FGFR3) and which blocks ligand-dependent activation of the FGFR3 or ligand-independent activation of the FGFR3 and heterodimeric combinations thereof, wherein the molecule comprises a V H region and a V L region, respectively, selected from the group consisting of SEQ ID NO:96 and SEQ ID NO:85; SEQ ID NO:98 and SEQ ID NO:87; and SEQ ID NO:106 and SEQ ID NO:95.