Patent ID: 6894052

Claim:
A compound of the formula wherein each of Ar and Ar′ is independently selected from the group consisting of phenyl and pyridyl, each optionally substituted by one or more members selected from the group consisting of alkyl, alkoxy, cyano, nitro, amino, alkylsulfonylamino, and alkylamino; Y is a member selected from the group consisting of nitrogen atom, CH, C—OH, and C—CN; R is a hydrogen atom or a lower alkyl group; B is selected from the group consisting of (i) phenyl, (ii) naphthyl, (iii) benzodioxanyl, and (iv) indolyl; wherein a phenyl ring of said B is optionally substituted with one or more substituents selected from the group consisting of hydrogen atom, alkyl, alkoxy, halogen, cyano, nitro, amino, alkylsulfonylamino and alkylamino; with the provisos that 1) when B is methoxyphenyl and Y is C—CN then Ar and Ar′ are not simultaneously unsubstituted phenyl; alkylphanyl; 2) when Y is CH, Ar and Ar′ cannot both be optionally substituted pyridyl; 3) when Y is CH and one of Ar and Ar′ is optionally substituted phenyl, the other of Ar′ and Ar cannot be optionally substituted pyridyl; and 4) when Y is CH or a nitrogen atom and each of Ar and Ar′ are optionally substituted phenyl wherein said substitution is methyl, then B is selected from the group consisting of (i) phenyl, (ii) naphthyl, (iii) benzodioxanyl, and (iv) indolyl; wherein a phenyl rind of said B is optionally substituted with one or more substituents selected from the group consisting of alkoxy, halogen, cyano, nitro, amino, alkylsulfonylamino and alkylamino groups; and enantiomers, diastereomers, N-oxides crystalline forms, hydrates and pharmaceutically acceptable salts thereof.