Patent ID: 8226965

Claim:
A method of killing a fungal, yeast, or mold agent to treat a fungal, yeast, or mold infection, or a combination thereof, in a human subject in need thereof comprising administering topically or intradermally to the human subject a nanoemulsion, wherein: (a) the nanoemulsion comprises droplets have an average diameter of less than about 400 nm; (b) the nanoemulsion droplets comprise: (i) an aqueous phase, (ii) soybean oil in an amount of about 1% to about 60%, (iii) at least one surfactant in an amount of about 0.001% to about 10%, wherein the surfactant is a polysorbate, cetylpyridinium chloride (CPC), or a combination thereof, and (iv) ethanol in an amount of about 0.1% to about 10%, organic solvent is an alcohol; and (c) the fungal, yeast, or mold agent is selected from the group consisting of (i) Trichophyton species selected from the group consisting of T. ajelloi, T. concentricum, T. equinum, T. erinacei, T. flavescens, T. gloriae, T. interdigitale, T. megnini, T. phaseoliforme, T. schoenleini, T. simii, T. soudanense, T. terrestre, T. tonsurans, T. vanbreuseghemii, T. verrucosum, T. violaceum , and T. yaoundei, (ii) Candida species selected from the group consisting of C. parapsiliosis, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. lusitaniae, C. kefvr, C. guilliermondii , and C. dubliniensis , (iii) Microsporum species selected from the group consisting of M. audouini, M. gallinae, M. ferrugineum, M. distortum, M nanum, M. cookie , and M. vanbreuseghemii , (iv) Epicoccum nigrum , (v) Aspergillus species selected from the group consisting of A. sydowii, A. terreus, A. niger, A. fumigatus, A. flavus, A. clavatus, A. glaucus group, A. nidulans, A. oryzae, A. ustus , and A. versicolor , (vi) Paecilomyces species selected from the group consisting of P. lilacinus and P. variotii , (vii) Fusarium species selected from the group consisting of F. oxysporum, F. solani , and F. semitectum , (viii) Acremonium species, (ix) Chaetomium species selected from the group consisting of C. atrobrunneum C. funicola C. globosum and C. strumarium (x) Phoma species, (xi) Scopulariopsis species selected from the group consisting of S. brevicaulis, S. candida, S. koningii, S. acremonium, S. flava, S. cinerea, S. trigonospora, S. brumptii, S. chartarum, S. fusca , and S. asperula , (xii) Scytalidium species selected from the group consisting of S. dimidiatum, S. hyalinum, S. infestans, S, japonicum, and S. lignicola , (xiii) Alternaria species selected from the group consisting of A. alternate, A. chartarum, A. dianthicola, A. geophilia, A. infectoria, A. stemphyloides , and A. teunissima , (xiv) Epicoccum species, (xv) Curvularia species selected from the group consisting of C. brachyspora, C. clavata, C. geniculata, C. lunata, C. pallescens, C. senegalensis , and C. verruculosa , and (xvi) Tinea species selected from Tinea pedis, Tinea unguium, Tinea corporis, Tinea cruris, Tinea capitis, Tinea manuum, Tinea faciale, Tinea versicolor , and Tinea barbae.