Patent ID: 8846898

Claim:
A compound having the structural formula (I), wherein R 1 is a protecting group removable by an elimination reaction; R 2 and R 3 are independently selected from the group consisting of hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl and substituted heteroatom-containing hydrocarbyl, or R 2 and R 3 are linked to form a substituted or unsubstituted, five- or six-membered nitrogen-containing heterocycle; R 4 is NR 5 R 6 , halogen or DL, wherein R 5 and R 6 are independently selected from the group consisting of hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl and substituted heteroatom-containing hydrocarbyl, or R 5 and R 6 are linked to form a substituted or unsubstituted, five- or six-membered nitrogen-containing heterocycle, D is O, S or NH, and L is a heteroatom-protecting group, unsubstituted hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl, or substituted heteroatom containing hydrocarbyl; X is O, S, NH, or NR 7 wherein R 7 is hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl or substituted heteroatom-containing hydrocarbyl; n is zero or 1; Y is —(Y′)m-(CR 8 R 9 )— wherein m is zero or 1, Y′ is hydrocarbylene, substituted hydrocarbylene, heteroatom-containing hydrocarbylene, or substituted heteroatom-containing hydrocarbylene, wherein R 8 and R 9 are independently selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl and substituted heteroatom-containing hydrocarbyl; and Z is O, S, NH or NR 10 wherein R 10 is as defined for R 7 wherein in any substituted moiety at least one hydrogen atom bound to a carbon atom is replaced by at least one of the following: alkoxy, thio, thioester, halo, amino, nitrile, nitro, sulfonyl, phosphoro, carboxyl, carbonyl, silyl and thienyl.