Patent ID: 8138174

Claim:
A compound of formula (1): or a tautomer, stereoisomer, N-oxide, or a pharmacologically acceptable salt of any of the foregoing, wherein: A is (A 2 ): wherein the wavy bond is the point at which the fragment is attached to moiety N (wherein N represents a non-basic nitrogen atom) in formula (1), R 1 and R 2 independently are chosen from a hydrogen atom, a trifluoromethyl group, and a halogen atom, R 4 is chosen from a hydrogen atom, a halogen atom, methyl, ethyl, trifluoromethyl, hydroxymethyl, fluoromethyl, 2,2,2-trifluoroethyl, propyl, methylsulfanyl, methylsulfinyl, methylsulfonyl, ethylsulfanyl, ethylsulfinyl, ethylsulfonyl, C 1 3 -dialkyl-aminomethyl, pyrrolidin-1-ylmethyl, piperidin-1-ylmethyl, and morpholin-4-ylmethyl group, and the NRTB sequence of formula (1) is chosen from one of the fragments (NRTB 1 ), (NRTB 2 ), (NRTB 3 ), (NRTB 5 ), (NRTB 6 ), (NRTB 7 ), (NRTB 8 ), (NRTB 9 ), and (NRTB 10 ): wherein R is chosen from a hydrogen atom and a (C 1 -C 3 )-alkyl group.