Patent ID: 7183320

Claim:
A compound of Formula I: where: X is O; R 1 is hydrogen, halo, C 1 –C 6 alkyl, C 1 –C 4 alkoxy, C 1 –C 4 alkylthio, CF 3 , OCF 3 , SCF 3 , (C 1 –C 4 alkoxy)carbonyl, nitro, azido, O(SO 2 )CH 3 , N(CH 3 ) 2 , hydroxy, phenyl, substituted phenyl, pyridinyl, thienyl, furyl, quinolinyl, or triazolyl; R 2 is hydrogen, halo, cyano, CF 3 , C 1 –C 6 alkyl, (C 1 –C 4 alkoxy)carbonyl, C 1 –C 4 alkoxy, phenyl, or quinolinyl; R 2a is hydrogen or C 1 –C 4 alkoxy; R 2b is hydrogen or C 1 –C 6 alkyl provided that at least one of R 2a and R 2b is hydrogen; R 3 is hydrogen, halo, C 1 –C 6 alkyl, CF 3 , or nitro; R 3a is hydrogen, halo, or C 1 –C 6 alkyl provided that when R 3a is C 1 –C 6 alkyl, R 3 is hydrogen and R 4 is halo; and R 4 is halo, C 1 –C 6 alkyl, or CF 3 provided that only one of R 3 and R 4 may be C 1 –C 6 alkyl and provided that when R 4 is halo or C 1 –C 6 alkyl only one of R 3 and R 3a is hydrogen; or a pharmaceutically acceptable base addition salt thereof, provided that: a) when R 3 and R 4 are both chloro and R 2 is hydrogen, R 1 is bromo, iodo, C 1 –C 4 alkoxy, C 1 –C 4 alkylthio, CF 3 , OCF 3 , nitro, azido, O(SO 2 )CH 3 , N(CH 3 ) 2 , hydroxy, phenyl, substituted phenyl, pyridinyl, thienyl, furyl, or triazolyl; b) when R 3 and R 4 are both chloro and R 1 is hydrogen, R 2 is bromo, fluoro, CF 3 , C 1 –C 6 alkyl, C 1 –C 4 alkoxy, phenyl, or quinolinyl.