Patent ID: 7772266

Claim:
A method for treatment of benign prostatic hyperplasia BPH), an enlarged prostate, acute urinary retention, or symptoms thereof or reducing prostate size in a mammal comprising administering to a mammal in need of such treatment an effective amount of a compound of Formula I-E: wherein A, B, C, and D are independently selected from the group consisting of CR 1 and N; wherein at least one of A, B, C, and D is CR 1 ; wherein R 1 is selected from the group consisting of H, alkyl, heteroalkyl, aryl, arylalkyl, and halogen; and wherein when two adjacent of A, B, C, and D are CR 1 , the two R 1 s may combine to form a single aryl, cycloalkyl, or heterocycloalkyl group; and R 2 is selected from the group consisting of alkyl, alkoxy and amide; R 3 is selected from the group consisting of H, methyl and —C=NH(NH2); or a pharmaceutically acceptable salt thereof.