Patent ID: 8425757

Claim:
An amperometric method for determining the concentration of an analyte in a sample, comprising: applying an input signal to a sample, the input signal comprising at least 3 duty cycles within 180 seconds and each duty cycle comprising an amperometric excitation and a relaxation, where the input signal has redox intensity of at least 0.01 over a 10 second duration of the input signal, and where the relaxations of the at least 3 duty cycles each provide an independent diffusion and analyte reaction time during which the analyte generates measurable species; measuring an output signal from one of the amperometric excitations having a duration from 0.01 second to 1.5 seconds, the output signal responsive to the measurable species; and determining a concentration of an analyte in the sample in response to the measured output signal, where the determined concentration is responsive to a rate at which the measurable species is oxidized or reduced by the input signal.