Patent ID: 8012901

Claim:
A method of synthesizing enantiopure Mexiletine Analogues and Novel β-Thiophenoxy and Pyridyl ethers comprising: reducing an O-benzyl oxime having the formula I: where R is a substituted or unsubstituted, alkyl, aryl group; Y is an oxygen atom or a sulfur atom and Ar is an aryl, alkyl, Pyridyl group; wherein said reduction is done in the presence of a catalyst agent having the formula II: where, the R and R1 groups are equal or different; a hydrogen atom or a substituted or unsubstituted, aryl, alkyl, cycloalkyl or aralkyl; R2 and R 3 groups are different; a hydrogen atom or a substituted or unsubstituted, alkyl, aryl, aralkyl group; and the R4 group is a H or a cycloalkyl or aralkyl group; and wherein the substituents R, R1, R2, R3, and R4 groups are substantially non-reactive.