Patent ID: 8718958

Claim:
A computer implemented method for detecting early signal attenuation in an analyte sensor, comprising: receiving a first plurality of analyte sensor related signals within a first predetermined time period after insertion of an analyte sensor into a user, wherein the first predetermined time period occurs within the first 24 hours of insertion; determining a probability of early signal attenuation associated with the analyte sensor based at least in part on the first plurality of analyte sensor related signals; receiving a second plurality of analyte sensor related signals during a second predetermined time period, wherein the second predetermined time period is offset from the first predetermined time period by a predetermined offset time; receiving a reference analyte measurement during the second predetermined time period; determining a sensitivity of the analyte sensor based on the second plurality of analyte sensor related signals and the reference analyte measurement; determining a sensitivity ratio based on the determined sensitivity of the analyte sensor divided by a nominal sensitivity, the nominal sensitivity determined at the time the analyte sensor is manufactured; verifying a presence of early signal attenuation when the determined sensitivity ratio is less than a first predetermined threshold level; and generating a first output signal with a processor associated with the verification of the presence of early signal attenuation.