Patent ID: 7531530

Claim:
A method for treating cancer in a mammal, wherein the cancer is of a type that is caused by a genetic defect in a gene that mediates homologous recombination and is selected from the group consisting of cancer of the: breast, lung, colon, pancreas, stomach, ovary, cervix, breast, prostate, bone, brain, and skin, the gene that mediates homologous recombination being selected from the group consisting of: XRCC1, CTPS, RPA, RPA1, RPA2, RPA3, XPD, ERCC1, XPF, MMS19, RAD51, RAD51, RAD51C, RAD51D, DMC1, XRCCR, XRCC3, BRCA1, BRCA2, RAD52, RAD54, RAD50, MRE11, NB51, WRN, BLM KU70, KU80, ATM, ATR CHK1, CHK2, FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, RAD1, RAD9 and combinations thereof, the method comprising: selecting the mammal having said genetic defect; and administering to the mammal a compound selected from the group consisting of a compound of the formula I, formula II and formula III: or a pharmaceutically acceptable salt thereof.