Patent ID: 8906928

Claim:
A compound having formula I: or a pharmaceutically acceptable salt or ester thereof, wherein: R 1 is -Q-T or -Q-X-T; R 2 is H, halogen, unsubstituted or substituted C 6 -C 10 aryl or unsubstituted or substituted heteroaryl comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C 3 -C 10 carbocycle or unsubstituted or substituted heterocycle comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S; R 3 is H, unsubstituted or substituted C 1 -C 6 alkyl, unsubstituted or substituted C 6 -C 10 aryl or unsubstituted or substituted C 6 -C 10 aryl-C 1 -C 6 alkyl; Q is a bond or unsubstituted or substituted C 1 -C 6 alkyl linker; X is O, S, NR 4 , C(O), C(O)O, C(O)NR 4 or CR 5 R 6 ; T is substituted C 1 -C 10 alkyl, unsubstituted or substituted C 2 -C 8 alkenyl, unsubstituted or substituted C 2 -C 8 alkynyl, unsubstituted or substituted amino, unsubstituted or substituted C 1 -C 6 alkylamino, unsubstituted or substituted di-C 1 -C 6 alkylamino, unsubstituted or substituted C 6 -C 14 aryl, unsubstituted or substituted C 6 -C 14 aryl-C 1 -C 6 alkyl, unsubstituted or substituted heteroaryl comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C 3 -C 10 carbocycle or unsubstituted or substituted heterocycle comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S; R 4 is H or unsubstituted or substituted C 1 -C 6 alkyl; and R 5 and R 6 are each independently H, unsubstituted or substituted C 1 -C 6 alkyl or unsubstituted or substituted C 1 -C 6 alkoxy.