Patent ID: 7807692

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: A is O or S; X is a bond or —C(R 7 ) 2 —; R 1 is selected from the group consisting of H and C 1 -C 3 alkyl, wherein C 1 -C 3 alkyl is optionally substituted with 1-3 halogens; each R 2 is independently selected from the group consisting of halogen, C 1 -C 3 alkyl, and —OC 1 -C 3 alkyl, wherein C 1 -C 3 alkyl and —OC 1 -C 3 alkyl are optionally substituted with 1-3 halogens; R 3 is selected from the group consisting of Y is selected from the group consisting of ═O and ═N—OH; D and Z are each independently selected from the group consisting of ═C(R 7 )— and ═N—; B is selected from the group consisting of —N(R 7 )—, —O— and —S—; each R 4 is independently selected from the group consisting of halogen, —OH, C 1 -C 3 alkyl, —OC 1 -C 3 alkyl, —OC(═O)C 1 -C 3 alkyl, and —S(O) q C 1 -C 3 alkyl, wherein C 1 -C 3 alkyl, —OC 1 -C 3 alkyl, —OC(═O)C 1 -C 3 alkyl, and —S(O) q C 1 -C 3 alkyl are optionally substituted with 1-5 halogens; each R 5 is independently selected from the group consisting of halogen, C 1 -C 3 alkyl, and —OC 1 -C 3 alkyl, wherein C 1 -C 3 alkyl and —OC 1 -C 3 alkyl are optionally substituted with 1-3 halogens; R 6 is selected from the group consisting of C 2 -C 5 alkyl, —CH 2 Cyclopropyl, C 3 -C 6 cycloalkyl, —OC 2 -C 5 alkyl and —C(═O)C 1 -C 3 alkyl, wherein the alkyl, cyclopropyl, and cycloalkyl groups of said R 6 substituent are optionally substituted with 1-3 halogens; each R 7 is independently selected from the group consisting of H and C 1 -C 3 alkyl, wherein C 1 -C 3 alkyl is optionally substituted with 1-3 F; m is an integer from 0-4; n is an integer from 0-5; p is an integer from 0-3; and q is an integer from 0-2.