Patent ID: 8492375

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 represents branched C 3-6 alkyl, C 3-5 cycloalkyl or —C 1-4 alkylC 3-4 cycloalkyl; R 2 represents halogen, C 1-6 alkyl, C 1-6 alkoxy, cyano, amino or trifluoromethyl; n represents 0, 1 or 2; R 3 represents —X-aryl, —X-heteroaryl, —X-heterocyclyl, —X-aryl-aryl, —X-aryl-heteroaryl, —X-aryl-heterocyclyl, —X-heteroaryl-aryl, —X-heteroaryl-heteroaryl, —X-heteroaryl-heterocyclyl, —X-heterocyclyl-aryl, —X-heterocyclyl-heteroaryl or —X-heterocyclyl-heterocyclyl; such that when R 3 represents —X-piperidinyl, —X-piperidinyl-aryl, —X-piperidinyl-heteroaryl or —X-piperidinyl-heterocyclyl said piperidinyl group is attached to X via a nitrogen atom; wherein R 3 is attached to the phenyl group of formula (I) at the 3 or 4 position; X represents a bond, O, CO, SO 2 , CH 2 O, OCH 2 , NR 4 , NR 4 CO or C 1-6 alkyl; R 4 represents hydrogen or C 1-6 alkyl; wherein said aryl, heteroaryl or heterocyclyl groups of R 3 may be optionally substituted by one or more halogen, hydroxy, cyano, nitro, oxo, haloC 1-6 alkyl, haloC 1-6 alkoxy, C 1-6 alkyl, C 1-6 alkoxy, arylC 1-6 alkoxy, C 1-6 alkylthio, C 1-6 alkoxyC 1-6 alkyl, C 3-7 cycloalkylC 1-6 alkoxy, C 3-7 cycloalkylcarbonyl, —COC 1-6 alkyl, C 1-6 alkoxycarbonyl, arylC 1-6 alkyl, heteroarylC 1-6 alkyl, heterocyclylC 1-6 alkyl, C 1-6 alkylsulfonyl, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyloxy, C 1-6 alkylsulfonylC 1-6 alkyl, arylsulfonyl, arylsulfonyloxy, arylsulfonylC 1-6 alkyl, aryloxy, —CO-aryl, —CO-heterocyclyl, —CO-heteroaryl, C 1-6 alkylsulfonamidoC 1-6 alkyl, C 1-6 alkylamidoC 1-6 alkyl, arylsulfonamido, arylaminosulfonyl, arylsulfonamidoC 1-6 alkyl, arylcarboxamidoC 1-6 alkyl, aroylC 1-6 alkyl, arylC 1-6 alkanoyl, or a group NR 15 R 16 , —NR 15 CO-aryl, —NR 15 CO-heterocyclyl, —NR 15 CO-heteroaryl, —CONR 15 R 16 , —NR 15 COR 16 , —NR 15 SO 2 R 16 or —SO 2 NR 15 R 16 groups, wherein R 15 and R 16 independently represent hydrogen or C 1-6 alkyl; with the proviso that 1) when X is CH 2 , R 3 is not phthalazin-1-one, 2) when X is NHCO, R 1 is not isopropyl.