Patent ID: 8377981

Claim:
An N-acyl O-amino CBI derivative represented by Formula I: wherein: R 1 is selected from the group of radicals consisting of —C(O)(C 1 -C 6 alkyl), —C(O)O(C 1 -C 10 alkyl), —C(O)(C 2 -C 6 alkenyl), —C(O)O(C 2 -C 6 alkenyl), and —C(O)aryl; R 2 is selected from the group of radicals consisting of hydrogen, —C(O)(C 1 -C 6 alkyl), —C(O)O(C 1 -C 10 alkyl), —C(O)(C 2 -C 6 alkenyl), and —C(O)O(C 2 -C 6 alkenyl); or, alternatively, R 1 and R 2 are combined to form a cyclic structure selected from the group consisting of divalent radicals represented as follows: R 3 is selected from group consisting of radicals represented as follows: wherein: R 4 is selected from group consisting of radicals represented as follows: R 5 , R 6 , R 7 and R 8 are each independently selected from the group of radicals consisting of —H, —OH, —O(C 1 -C 6 alkyl), —(C 1 -C 6 alkyl) and halogen; and R 9 is selected from the group of radicals consisting of —H, —C(O)O(C 1 -C 6 alkyl), —C(O) (C 1 -C 6 alkyl), —C(O)NH 2 , —C(O)NHNH 2 , and —C(O)NHNHC(O)O(C 1 -C 6 alkyl).