Patent ID: 7968307

Claim:
A method for detecting the presence of a STEAP-1 polynucleotide in a biological sample, comprising (a) contacting the sample with a polynucleotide probe which specifically hybridizes under hybridization and wash conditions comprising hybridization in 50% formamide/6×SSC/0.1% SDS/100 μg/ml ss DNA at a temperature above 37° C. and washing in 0.1×SSC/0.1% SDS at a temperature above 55° C. to a polynucleotide selected from the group consisting of (i) the STEAP-1 cDNA contained within plasmid 8P1D4 clone 10.1 as deposited with American Type Culture Collection as Accession No. 98849; (ii) a polynucleotide having the sequence as shown in SEQ ID NO. 1, wherein T can also be U; and (iii) a polynucleotide encoding a STEAP-1 protein comprising the amino acid sequence shown in SEQ ID NO:2 or the complements thereof; and (b) detecting the presence of a hybridization complex formed by the hybridization of the probe with STEAP-1 polynucleotide in the sample, wherein the presence of the hybridization complex indicates the presence of STEAP-1 polynucleotide within the sample.