Patent ID: 8865918

Claim:
A method for modulating an activity of an androgen receptor comprising contacting an androgen receptor with a compound of Formula (II): wherein: R 1 is NO 2 or CN; R 2 is selected from among F, Cl, Br, I, SR A , NO 2 , and CF 3 ; R 3 and R 4 are each independently selected from hydrogen, F, Cl, OR A , an optionally substituted C 1 -C 4 alkyl, and CF 3 ; R 5 is hydrogen; R 10 is hydrogen; R 6a and R 7a are each independently hydrogen or an optionally substituted C 1 -C 6 alkyl; R 9 is selected from an optionally substituted C 1 -C 8 alkyl, C 1 -C 8 heteroalkyl, CH(R D )OR A , CH(R D )NR A R B , and COR A ; R 12 and R 13 are each independently selected from hydrogen, F, Cl, OR A , and (CH 2 ) m R C ; R A is hydrogen; R B is hydrogen; R C is selected from an optionally substituted aryl and an optionally substituted heteroaryl that is optionally with a substituent selected from F, Cl, Br, I, CN, OR A , NO 2 , NR A R B , SR A , SOR A , SO 2 R A , an optionally substituted C 1 -C 4 alkyl, CF 3 , and an optionally substituted C 1 -C 4 heteroalkyl; R D is hydrogen or CF 3 ; Z is CR A R B ; n is 0; and in is 1 or 2, or a pharmaceutically acceptable salt thereof.