Patent ID: 8518934

Claim:
A compound having Formula I: or a pharmaceutically acceptable salt thereof, wherein: R 1 is optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted amino, optionally substituted carbamoyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl, R 2 is hydrogen or optionally substituted alkyl, or R 1 and R 2 can be taken together with the adjacent atoms to form a ring; Y is CR 3 R 4 or SO m ; R 3 and R 4 are each independently hydrogen, cyano, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl, or R 3 and R 4 can be taken together with the neighboring carbon atom to form a ring; Z is optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl, NR 5 R 6 , COR 5 or CONR 5 R 6 ; each X is independently ═O, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, halogen, cyano, nitro, NR 5 R 6 , OR 5 , SR 5 , COR 5 , COOR 5 , CONR 5 R 6 , NR 5 COR 6 , OCOR 5 , SOR 5 , SO 2 R 5 , SO 3 R 5 , SONR 5 R 6 , SO 2 NR 5 R 6 , NR 5 SOR 6 , or NR 5 SO 2 R 6 ; R 5 and R 6 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl; m is 1 or 2; p is 0, 1 or 2; and q is 0 or 1; and provided that when q is 0, X is not OH or COOR 5 .