Patent ID: 7766658

Claim:
A method for intra-oral diagnosis and treatment, comprising: removeably placing a dental appliance on a patient's teeth, the appliance including: a number of cavities that conform to the patient's teeth, but are slightly out of alignment with a current configuration of the patient's teeth; one or more sensors attached to the dental appliance; a processor located on the dental appliance; one or more delivery nozzles that project from the dental appliance and are shaped to conform with with a respective periodontal pocket of the patient; and one or more reservoirs in fluid communication with the one or more delivery nozzles; sampling an intra-oral substance with the sensor; detecting one or more medical conditions with the processor based on output received from the sensor regarding the intra-oral substance; providing treatment in a closed-feedback loop, including: activating the one or more delivery nozzles that project from the appliance and insert into the respective periodontal pocket of the patient; and delivering drugs or therapeutic agents from one or more reservoirs through the delivery nozzles to the patient.