Patent ID: 7511064

Claim:
A compound according to the formula or a pharmaceutically acceptable salt thereof, wherein R 1 is selected from the group consisting of ethyl, propyl, isopropyl, butyl, isobutyl, pentyl, hexyl, ethoxy, propoxy, isopropoxy, butoxy, isobutoxy, phenoxy, trifluoromethyl, trifluoromethoxy, amino, dimethylamino, â€”CON(CH 3 ) 2 and â€”CON(C 2 H 5 ) 2 ; R 2 is a methyl, ethyl, propyl, isopropyl, butyl, isobutyl, pentyl, hexyl, hydroxy or hydrogen, or R 1 and R 2 together form a five-membered heterocycle, wherein a heteroatom in said heterocycle is an oxygen atom; R 3 is selected from the group consisting of methyl, ethyl, propyl, isopropyl, butyl isobutyl, pentyl, hexyl, hydroxy and hydrogen; R 4 is selected from the group consisting of hydroxy, methoxy, ethoxy, propoxy, isopropoxy, butoxy, isobutoxy, trifluoromethyl, amino, dimethylamino, diethylamino, fluorine, bromine, methyl, ethyl, propyl, isopropyl, butyl and hydrogen; R 5 is methyl or hydrogen; R 6 is methyl or ethyl; and X is N or Se; wherein said compound is a selective 5-HT2B receptor antagonist relative to 5-HT2A and 5-HT2C receptors.