Patent ID: 7858631

Claim:
A compound of formula IA or IC wherein Z 1 is N; Z 2 is CR 5 : Z 3 is CR 6 : R 1 is a substituted or unsubstituted arylalkyl, or alkyl group; R 3 is H; R 5 and R 6 are each H; W is a group of formula IIA or IIB; R 1′ and R 2′ , together with the nitrogen to which they are bound, form a substituted or unsubstituted heterocyclyl group, wherein the heterocyclyl group is piperazine; R 3′ is a substituted or unsubstituted cycloalkyl group; R 4′ is H; and pharmaceutically acceptable salts thereof, stereoisomers thereof, or tautomers thereof; wherein the term “substituted” refers to a group in which one or more bonds to a hydrogen atom contained therein are replaced by a bond to a halogen atom, hydroxyl groups, alkoxy groups, aryloxy groups, and ester groups; thiol groups, alkyl and aryl sulfide groups, sulfone groups, sulfonyl groups, and sulfoxide groups; imines, amides, alkylamines, dialkylamines, arylamines, alkylarylamines, diarylamines, N-oxides, imides, and enamines; trialkylsilyl groups, dialkylarylsilyl groups, alkyldiarylsilyl groups, and triarylsilyl groups; substituted alkyl groups and substituted cycloalkyl groups also include groups in which one or more bonds to a carbon (s) or hydrogen (s) atom is replaced by a bond to oxygen in carbonyl, carboxyl, and ester groups; or nitrogen in imines, oximes, hydrazones, and nitriles; substituted cycloalkyl, substituted aryl, substituted heterocyclyl and substituted heteroaryl also include rings and fused ring systems in which a bond to a hydrogen atom is replaced with a bond to an alkyl group.