Patent ID: 7312233

Claim:
A compound having a formula: or a pharmaceutically acceptable salt thereof, and stereoisomers and tautomers thereof, wherein: A is CR 5 R 6 ; each of R 3′ , R 5 , R 5′ and R 6 is independently selected from H, halo, haloalkyl and hydroxyalkyl; provided that only one of R 3′ , R 5 , R 5′ and R 6 is other than H at any one time; each of W and X is independently CH, CMe, CCl or CF; each Y and Z is independently CR 4 ; R 1 is 3-quinolinyl, unsubstituted or substituted with alkyl, hydroxyalkyl, haloalkyl, amino, alkylamino, dialkylamino, arylamino, alkylarylamino, alkoxy, cycloalkylalkoxy, alkoxycarbonyl, arylalkyloxy, aralkyl, sulfo, sulfonyl, sulfanyl, aminosulfonyl, carboxy, carbamoyl, cyano, halo, hydroxy, nitro or thiol; R 3 is selected from halo, C 1 -C 6 alkyl, halo C 1 -C 6 alkyl, or hydroxy C 1 -C 6 alkyl; and each R 4 is independently hydrogen, alkyl, hydroxyalkyl, haloalkyl, amino, alkylamino, dialkylamino, arylamino, alkylarylamino, alkoxy, cycloalkylalkoxy, alkoxycarbonyl, arylalkyloxy, aralkyl, sulfo, sulfonyl, sulfanyl, aminosulfonyl, carboxy, carbamoyl, cyano, halo, hydroxy, nitro or thiol.