Patent ID: 7858786

Claim:
A compound of formula IC: or a pharmaceutically acceptable salt thereof; wherein W is F, OR′, SR′, N(R′) 2 , CHF 2 , or CH 2 F; R 1 and R 2 , taken together with the nitrogen atom to which they are bound, form a pyrrolidinyl ring, a piperidinyl ring or a piperazinyl ring: wherein z is 0-5; y is 0-3; R 3a is hydrogen; R 3b is hydrogen; each occurrence of R 4 is independently COOR′, —NRCOR′, —CON(R′) 2 , —OCON(R′) 2 , —COR′, —NHCOOR′, or —SO 2 R′; each occurrence of R 5 is independently halogen, CN, NO 2 , —N(R′) 2 , —CH 2 N(R′) 2 , —OR′, —CH 2 OR′, —SR′, —CH 2 SR′, —NRCOR′, —CON(R′) 2 , —S(O) 2 N(R′) 2 , —OCOR′, —COR′, —CO 2 R′, —OCON(R′) 2 , —NR′SO 2 R′, —OP(O)(OR′) 2 , —P(O)(OR′) 2 , —OP(O) 2 OR′, —P(O) 2 OR′, —PO(R′) 2 , —OPO(R′) 2 , or an optionally substituted group selected from C 1 -C 6 aliphatic, aryl, heteroaryl, cycloaliphatic, heterocycloaliphatic, arylC 1 -C 6 alkyl, heteroarylC 1 -C 6 alkyl, cycloaliphaticC 1 -C 6 alkyl, or heterocycloaliphaticC 1 -C 6 alkyl; each occurrence of R is independently hydrogen or an optionally substituted C 1-6 aliphatic group; each occurrence of R′ is independently hydrogen or an optionally substituted C 1-6 aliphatic group, a 3-8-membered saturated, partially unsaturated, or fully unsaturated monocyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or an 8-12 membered saturated, partially unsaturated, or fully unsaturated bicyclic ring system having 0-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or R and R′, two occurrences of R, or two occurrences of R′, are taken together with the atom(s) to which they are bound to form an optionally substituted 3-12 membered saturated, partially unsaturated, or fully unsaturated monocyclic or bicyclic ring having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; provided that: in formula IC: when R 3a and R 3b both are hydrogen, y is 0, and W is OH, then R 1 and R 2 taken together is not piperidin-1-yl.