Patent ID: 7232821

Claim:
A compound of formula (II): wherein: R 1 is CO 2 H; R 2 is halo, optionally substituted C 1-6 alkyl, CN, SC 1-6 alkyl, or SO 2 C 1-6 alkyl; each R 3 is independently halo, optionally substituted OC 1-6 alkyl, or optionally substituted C 1-6 alkyl; R 5 is hydrogen or an optionally substituted alkyl; R 6 is hydrogen or an optionally substituted alkyl, optionally substituted SO 2 aryl, optionally substituted SO 2 heterocyclyl group, CN, optionally substituted CH 2 aryl or COR 7 ; R 7 is hydrogen, optionally substituted heteroaryl or optionally substituted aryl; R 10 and R 11 together with the nitrogen atom to which they are attached form a morpholine ring, a 5- or 6-membered lactam ring or a 5- or 6-membered cyclic sulphonamide m is an integer from 0 to 3; n is an integer from 0 to 2; W, X, Y and Z are each CR 12 or N wherein at least two of W, X, Y or Z is CR 12 ; and when each of W, X, Y, and Z is CR 12 then each R 12 is independently selected from hydrogen, halogen, NR 5 R 6 , NHCOC 1-6 alkyl, NHSO 2 C 1-6 alkyl, C 1-6 alkyl and NR 10 R 11 , and when at least one of W, X, Y and Z is N then each R 12 is selected from hydrogen and NH 2 ; or a pharmaceutically acceptable salt, ester, salt of such ester, or solvate thereof.