Patent ID: 8685961

Claim:
A compound of the formula Ia: wherein: R 1 is selected from the group consisting of: (1) phenyl, (2) biphenyl, (3) 2,6-dimethoxyphenyl, (4) 2,4-dichlorophenyl, (5) 2,6-dichlorophenyl, (6) 2,3-difluorophenyl, (7) 2,4-difluorophenyl, (8) 2,6-difluorophenyl, (9) 2-methoxy-4-methyl-phenyl, (10) 3-methoxy-biphenyl, (11) 3-methyl-biphenyl, and (12) 5-methyl-2-triazolyl-phenyl; R 2 is selected from the group consisting of: (1) benzimidazolyl, (2) benzothiazolyl, (3) benzoxazolyl, (4) quinazolinyl, (5) quinolinyl, (6) thiadiazolyl, which is unsubstituted or substituted with halogen, hydroxyl, C 1-6 alkyl, â€”Oâ€”C 1-6 alkyl or phenyl; R 3 and R 4 are selected from the following options: R 3 and R 4 are hydrogen, R 3 is fluoro and R 4 is hydrogen, R 3 is hydroxyl and R 4 is hydrogen, R 3 is â€”NHâ€”C 1-6 alkyl and R 4 is hydrogen, R 3 is â€”Oâ€”C 1-6 alkyl and R 4 is hydrogen, or R 3 and R 4 taken together form Câ•O; or a pharmaceutically acceptable salt thereof.