Patent ID: 7781607

Claim:
A method for producing a coordination compound through reaction of a platinum complex with a polymer having carboxyl groups on its side chains, wherein a diaquoplatinum complex or a bis(nitrato)platinum complex and a dihalo-platinum complex which is selected from dichloro-, diiodo- or dibromo-platinum complexes are used in mixed state as the platinum complex, wherein the mixed state is formed by adding a halide ion selected from the group consisting of chloride, iodide and bromide ions to an aqueous solution of bis(nitrato)platinum complex or by adding a halide ion selected from the group consisting of chloride, iodide and bromide ions to aqueous solution of bis(nitrato)(1,2-cyclohexanediamine)platinum(II), and a block copolymer represented by the following general formula (1) or (2): wherein R 1 represents hydrogen atom or an unsubstituted or substituted linear or branched C 1 -C 12 alkyl group, L 1 and L 2 represent, independently of each other, linking groups, R 2 represents methylene group or ethylene group, R 3 represents hydrogen atom, a protecting group of amino group, hydrophobic group or polymerizable group, R 4 represents hydroxyl group, protected carboxyl group as formed together with the terminal —CO, or a hydrophobic group, R 5 s each independently represent a hydrogen atom, alkali metal ion or a protecting group of carboxyl group, m represents an integer of 5 to 20,000, n represents an integer of 2 to 5,000, and x represents an integer of 0 to 5,000, with the proviso that x is not larger than n, and hydrogen atom or alkali metal ion occupies 50% or more of n−x and x R 5 s, is used as the polymer, the method comprising a step of carrying out the reaction in an aqueous medium under the conditions in which the platinum complexes and the block copolymer mutually form a coordination compound, and a step of recovering the so formed coordination compound from the reaction mixture.