Patent ID: 8513289

Claim:
A compound represented by chemical formula (I) or a pharmaceutically acceptable salt thereof, wherein: L is selected from the group consisting of: (a) —C(O)—, (b) —CH(OH)— (c) —CH(NR 3 R 4 )— (d) —C(═NOR 3 )—, (e) —CH 2 —, and (f) —S(O) n —, wherein n is 0, 1 or 2; Ar 1 is an optionally mono, di- or tri-substituted phenyl or heteroaromatic ring of 6 atoms, wherein the heteroaromatic ring may contain 1, 2 or 3 heteroatoms selected from N, S and O, wherein the substituents are independently selected from the group consisting of: (a) halo, (b) —C 1-4 alkyl, (c) —O—C 1-4 alkyl, (d) —CF 3 , (e) —NH 2 , (f) —NH—CH 3 , (g) —CN, (h) —C(O)NH 2 , and (i) —S(O) n —CH 3 ; Ar 2 is an optionally substituted thiadiazole or oxadiazole ring wherein thesubstituent is a phenyl or a 5 or 6 membered mono-cyclic heteroaromatic or heterocyclic ring, or a bicyclic heteroaromatic or heterocyclic ring of 9 or 10 atoms, said heteroaromatic or heterocyclic ring containing 1, 2 or 3 hetero atoms selected from the group consisting of S, O and N, where in said phenyl, heteroaromatic or heterocyclic ring is optionally mono or di-substituted with substituents independently selected from the group consisting of: (a) halo, (b) —C 1-6 alkyl, optionally substituted with 1 to 4 fluorine atoms (c) —O—C 1-6 alkyl, (d) —CF 3 , (e) —NH 2 , (f) —NH—CH 3 , (g) —NH—CH 2 CF 3 , (h) —C(O)-morpholinyl, (i) —C(O)—NR 1 R 2 , (j) —C(O)OH, (k) —CN, (l) oxo, and (m) C 3-6 cycloalkyl; R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of (a) hydrogen, and (b) C 1-4 alkyl, or R 1 and R 2 or R 3 and R 4 may be joined together to form a 5 or 6 membered saturated ring, said ring optionally containing a heteroatom selected from S, N and O.