Patent ID: 8034048

Claim:
A tissue patch for treatment of a lesion in an esophagus of an alimentary tract of a patient, comprising: a tissue implant having a top surface and a bottom surface; and a substrate completely surrounding the tissue implant such that the substrate forms a first layer on the top surface and a second layer on the bottom surface, wherein at least one of the first and second layers contacts the respective top or bottom surface and is entirely bio-absorbable so that the tissue implant touches an area of the patient's tissue upon dissolving of the at least one of the first and second layers, wherein the first layer has a first predetermined thickness and the second layer has a second predetermined thickness different from the first predetermined thickness, wherein the second layer is configured to contact the lesion while the first layer is configured to face a lumen of the alimentary tract, and wherein the first predetermined thickness is greater than the second predetermined thickness.