Patent ID: 7022712

Claim:
A pharmaceutical composition comprising: a benzimidazole compound having a pKa below about 7 and having the formula: wherein X is hydrogen, halogen, alkyl of less than 7 carbon atoms or alkoxy of less than 7 carbon atoms; n is a positive integer of less than 4; Y is hydrogen, chlorine, nitro, methyl, ethyl or oxychloro; R is hydrogen, alkylaminocarbonyl wherein the alkyl group has from 3 to 6 carbon atoms or an alkyl group having from 1 to 8 carbons, and R 2 is 4-thiazolyl, NHCOOR 1 wherein R 1 is an aliphatic hydrocarbon of less than 7 carbon atoms, or an alkyl group of less than 7 carbon atoms; or a compound of formula: where n is an integer from 1 to 3 and R is hydrogen, alkyl having from 1 to 7 carbon atoms, chloro, bromo, fluoro, oxychloro, hydroxy, sulfhydryl or alkoxy having the formula —O(CH 2 ) y CH 3 wherein y is an integer from 0 to 6; its pharmaceutically acceptable salt or its conventional prodrug of the hydroxy, amine or sulfhydryl group; an aqueous buffer solution of phosphoric acid and sugar with a pH between 1 and 2; and optionally pharmaceutically acceptable additives, wherein the composition has a pH below about 4.