Patent ID: 7662578

Claim:
A method for determining the renal status of a mammalian subject within 48 hours following a renal-injury causing event or onset of a condition that affects an acute change in renal status, the method comprising the steps of: a) performing an assay on a body fluid sample obtained from a mammalian subject having, or suspected or prone to having, an acute renal tubular cell injury, wherein the sample is obtained within 48 hours after said acute renal tubular cell injury; b) obtaining an assay result, wherein the assay detects in the sample the presence of a protein selected from the group consisting of aprotinin, alpha-1-microglobulin, alpha-1-acid-glycoprotein, microalbumin, and combinations thereof the presence thereof serving as an early biomarker of acute renal tubular cell injury; and c) evaluating the subject's renal status based at least in part on the assay result.