Patent ID: 8034917

Claim:
An oligonucleotide composition comprising: a mixture of at least 2 sets of oligonucleotides, wherein each of said sets of oligonucleotides comprises at least 10 different oligonucleotides of the following formula: X 1 —V—X 2 , wherein: X i and X 2 provide binding sites for a pair of PCR primers; V is a variable region that has a variable nucleotide sequence that is complementary to one or more regions of a mammalian genome; the nucleotide sequence of X 1 is the same for each oligonucleotide of a set and different for oligonucleotides of different sets; the nucleotide sequence of X 2 is the same for each oligonucleotide of a set and different for oligonucleotides of different sets; and the variable regions of each set are complementary to a plurality of different regions of said mammalian genome.