Patent ID: 8313778

Claim:
A particulate drug delivery system, comprising: a polymeric carrier, at least one signal peptide for transport through a biological barrier consisting of the amino acid sequence of SEQ ID No: 3, and at least one active ingredient selected from the group consisting of antibodies, peptide hormones, receptors or peptidic ligands thereof, enzymes, interferons, tumor necrosis factor, cachectin, dihydrofolate reductase, lymphotoxin, interleukins, tumor suppressor proteins, plasmin, urokinase, hirudin, streptokinase, urokinase, tissue plasminogen activator, protein C, protein S, phospholipase A 2 , uromodulin, Tamm-Horsfall protein, insulin, trypsin inhibitor, lysozyme, thymopoietin, peptide antibiotics, erythropoietin, hepatotherapeutic substances, neuroprotective substances, immunotherapeutics, immunosuppressants, low molecular weight active ingredients for cardiovascular disorders or cancer, analgesics, low molecular weight anti-inflammatory, antibiotic antimicrobial active ingredients, low molecular weight hormones, nucleic acid fragments, nucleic acids, nucleoside analogs, β-interferons, α-lipoic acid, peptide analogs, enzyme or receptor agonists, enzyme or receptor antagonists, prostaglandins, steroids, cytostatics, heterocyclic antibiotics and prodrugs thereof, wherein the polymeric carrier, signal peptide and active ingredient have no covalent linkages with one another.