Patent ID: 8410071

Claim:
A method for treating cancer, said method comprising administering a composition comprising a therapeutically effective amount of an LNA oligonucleotide consisting of the sequence: 5′-T s G s G s c s a s a s g s c s a s t s c s c s T s G s T s a-3′ (SEQ ID NO. 1) wherein capital letters designate a beta-D-oxy-LNA nucleotide analogue, lower case letters designate a 2-deoxynucleotide, and subscript “s” designates a phosphorothioate link between neighboring nucleotides/LNA nucleotide analogues, and an agent selected from the group consisting of a chemotherapeutic agent, an anti-inflammatory agent, an antiviral agent, a cytostatic agent, an anti-angiogenic agent, an anti-proliferative agent, a pro-apoptotic agent, a signal transduction modulating agent, a kinase inhibitor and an immuno-modulating agent, to a patient in need thereof.