Patent ID: 7381801

Claim:
A chimerized GM-CSF specific antibody consisting of a light chain, the amino acid sequence of which consists of, in N terminal to C terminal order, the amino acids encoded by nucleotides 1357-1752 of SEQ ID NO: 35, followed by the amino acid sequence encoded by nucleotides 1886-2203 of SEQ ID NO: 35, and a heavy chain, the amino acid sequence of which consists of, in N terminal to C terminal order, the amino acids encoded by nuoleotides 1357-1764 of SEQ ID NO: 36, followed by the amino acid sequence encoded by nucleotides 1839-2825 of SEQ ID NO: 36, wherein said chiinerized GM-CSF specific antibody inhibits TF-1 cell growth by more than 50% at a concentration of 10 μg/ml in the presence of 0.5 ng/ml recombinant human GM-CSF.