Patent ID: 7176318

Claim:
A process for the preparation of a compound of formula (F) (wherein R 2 represents COOH or COO-C 1-6 alkyl; and R 3 represents hydrogen, mesylate, triflate, tosylate or carboxy-C 1-6 -alkyl) or a salt thereof comprising: (I) reacting a compound of formula (B) (wherein R 1 represents hydrogen; and R 2 is as hereinbefore defined) or a salt thereof with a copper and/or silver compound in the presence of palladium or a compound thereof to yield a compound of formula (C) (wherein R 1 and R 2 are as hereinbefore defined); (II) converting said compound of formula (C) into a compound of formula (E) (wherein R 2 and R 3 are as hereinbefore defined and R 4 represents a halogen atom) or a salt thereof; and (III) reacting said compound of formula (E) with azacyclonol.