Patent ID: 8486897

Claim:
A compound of formula (I): or a pharmaceutically acceptable addition salt thereof with organic and inorganic acid, a tautomer, an isomer or a mixture of isomers in any proportion, wherein: X represents a fluorine atom; R represents CH 2 OH; R1, R2 and R3 represent OH; R4 represents a hydrogen atom, an halogen atom or an OH or OR 11 group; R 0 represents a hydrogen atom or OH; and A represents an aryl or aryl-(C 1 -C 6 )-alkyl-aryl group, optionally substituted with one or more groups chosen among an halogen atom, a CN, SO 2 , SiR a R b R c , (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 3 -C 7 )-cycloalkyl, 5 to 7 ring-membered heterocycloalkyl, aryl, heteroaryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl-aryl, (C 1 -C 6 )-alkyl-heteroaryl, OR 11 , COR 11 , OCOR 11 , CO 2 R 11 , NR 12 R 13 , NR 12 COR 11 , CONR 12 R 13 , SR 11 , SO 2 R 11 , CSR 11 and OSO 3 R 11 group, the whole being optionally substituted with one or more groups chosen among an halogen atom, an OH, (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy, COOH and CHO group; with: R 11 representing a (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 3 -C 7 )-cycloalkyl, 5 to 7 ring-membered heterocycloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl or (C 1 -C 6 )-alkyl-aryl group, this group being optionally substituted with one or more groups chosen among an halogen atom, an OH, COOH and CHO group; R 12 and R 13 representing, independently from one another, a hydrogen atom or a (C 1 -C 6 )-alkyl or aryl-(C 1 -C 6 )-alkyl group; and R a , R b and R c representing, independently from one another, a (C 1 -C 6 )-alkyl, aryl or aryl-(C 1 -C 6 )-alkyl group; with the proviso that when R 0 is different from a hydrogen atom, then R4 represents a hydrogen atom.