Patent ID: 6933384

Claim:
A compound having the structure: wherein: X 1 and X 2 is, independently, H, Me, F, Cl, Br, I, SO 3 H, CO 2 H, CONH 2 , CONMe 2 , CN, or NO 2 ; X 3 is NHCH 2 R, or NHSO 2 R, wherein R is CH 2 COOH, CH 2 CH 2 NG 1 G 2 , substituted 2-hydroxyphenyl, or a five or six-membered heterocyclic ring, G 1 and G 2 is, independently, H, Me, Et, CH 2 CH 2 OH, or together are —(CH 2 ) 4 —, —(CH 2 ) 5 —, —CH 2 CH 2 OCH 2 CH 2 —, or —CH 2 CH 2 NHCH 2 CH 2 —; X 4 is H, Me, F, Cl, Br, I, SO 3 H, CO 2 H, CN, OMe, NHCH 2 R, or NHSO 2 R, wherein R is as defined above; each of Y 1 and Y 2 is H, or taken together are —O—, —S—, —Se—, —CMe 2 -, —NH—, —NMe-, or —NPh-; A is N, CH, C—CN, C—CF 3 , C—CH 2 CH 2 COOH, C—CH═CHCOOH, or: wherein: Z 1 is H, CO 2 H, or SO 3 H; each of Z 2 and Z 5 is, independently, H, F, or Cl; each of Z 3 and Z 4 is, independently, H, F, Cl, CO 2 H, NO 2 , NH 2 , NCS, NHCOCH 2 I, SCH 2 COOH, SCH 2 CH 2 NH 2 , (N-succinimidyl)oxycarbonyl, (N-succinimidyl)oxycarbonylmethylthio, N-maleimidyl, 3,5-dichloro-2,4,6-triazinylamino, CONHQ, or SO 2 NHQ, wherein Q is H, C 1 -C 20 alkyl, (CH 2 ) m COOH, (CH 2 ) n NH 2 , or (CH 2 CH 2 O) k CH 2 CH 2 NH 2 , wherein m is 1 to 11, n is 2 to 12, and k is 1 to 3, or tautomers and physiologically acceptable salts thereof.