Patent ID: 8207335

Claim:
Method of preparing compounds of general formula I wherein m denotes the number 1 or 2, n denotes the number 0, 1 or 2, R 1 denotes C 1-3 -alkyl or C 3-6 -cycloalkyl and R 2 denotes H or C 1-3 -alkyl, the enantiomers, the diastereomers, the mixtures and the salts thereof, comprising the steps of: (a) reacting 3,5-dimethylanisol with chlorosulphonic acid; (b) reacting 4-methoxy-2,6-dimethylsulphonyl chloride obtained in step (a) with a compound of general formula II wherein R 2 is defined as mentioned hereinbefore; (c) reacting a compound of general formula III obtained in step (b) wherein R 2 is defined as mentioned hereinbefore, with a compound of general formula IV wherein X denotes a hydrogen atom, an alkali metal or a C 1-4 -alkyl group, and Y denotes a halogen atom; (d) coupling a compound of general formula V obtained in step (c) wherein R 2 is defined as mentioned hereinbefore and X denotes a hydrogen atom, an alkali metal, or a C 1-4 -alkyl group, with a compound of general formula VI wherein m, n, R 1 and R 2 are defined as mentioned hereinbefore and o denotes one of the numbers 0, 1, 2 or 3; and (e) isolating a compound of general formula I obtained in step (d).