Patent ID: 6960579

Claim:
A compound of the formula Wherein the dashed bond represents a single or double bond; Aryl signifies a monocyclic heteroaromatic ring selected from the group consisting of thiophene, furan, pyrrole, pyridine, pyrimidine, pyridazine, and pyrazine; R 1 is H, OH, OC 1-3 alkyl, C 1-3 alkyl, C 1-3 alkyl substituted optionally with OH, or OC 1-3 alkyl; R 2 is H, halogen, C 1-3 alkyl, CONR 5 R 6 , S(═O) m C 1-3 alkyl, or C 1-3 alkyl substituted optionally with OH, or OC 1-3 alkyl; with the proviso that if Aryl is thiophene, then R 2 ≠H or halo, and R 1 ≠OH; R 3 , R 4 are independently H, C 1-3 alkyl, or C 1-3 alkyl substituted optionally with OH or OC 1-3 alkyl; R 5 , R 6 are independently H, C 1-3 alkyl, or C 2-3 alkyl substituted optionally with OH, OC 1-3 alkyl, where R 5 and R 6 optionally can be joined together to form a pyrrolidine or piperidine ring which can be either unsubstituted or substituted optionally with C 1-3 alkyl, C 2-3 alkyl substituted optionally with OH or OC 1-3 alkyl; R 7 , R 8 are together with the nitrogen atom to which they are attached incorporated into a heterocyclic ring selected from the group consisting of pyrrolidine, piperidine, Δ 3 -piperidein, piperazine, morpholine or thiomorpholine which can be unsubstituted or substituted on carbon with one or more substituents optionally selected from C 1-3 alkyl, or C 1-3 alkyl substituted optionally with OH, OC 1-3 alkyl, or phenyl which can be unsubstituted or substituted optionally with halogen, CF 3 , OC 1-3 alkyl, or C 1-3 alkyl, or substituted on nitrogen with C 1-4 alkoxy or phenyl which can be unsubstituted or substituted optionally with halogen, CF 3 , OC 1-3 alkyl, or C 1-3 alkyl; n is 2 to 4; m is 0, 1 or 2 or a pharmaceutically acceptable salt thereof.