Patent ID: 8426430

Claim:
A compound of the following formula: and/or a pharmaceutically acceptable salt thereof, in which each of R 1 , R 2 , and R 5 , independently, is H, halo, nitro, amino, cyano, hydroxy, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, alkoxy, alkylthio, alkylcarbonyl, carboxy, alkoxycarbonyl, carbonylamino, sulfonylamino, aminocarbonyl, or aminosulfonyl; one of R 3 and R 4 is in which R a is H, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and each of R d and R e , independently, is H, alkyl, alkenyl, or alkynyl, provided that R d and R e are not H simultaneously; or R d and R e , together with the nitrogen to which they are attached, form a 3-12 membered saturated, unsaturated, or aromatic ring containing 1-3 heteroatoms selected from N, O, and S; and the other of R 3 and R 4 is H, halo, nitro, amino, cyano, hydroxy, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, alkoxy, alkylthio, alkylcarbonyl, carboxy, alkoxycarbonyl, carbonylamino, sulfonylamino, aminocarbonyl, or aminosulfonyl; X is NR f , wherein R f is H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, or aminosulfonyl; Y is phenyl optionally substituted with akynyl, or optionally fused with 3-8 membered ring; and Z is N.