Patent ID: 7705019

Claim:
A compound represented by the structural formula IA or a pharmaceutically acceptable salt thereof, wherein: Y is R—X—; X is selected from the group consisting of —C(R 13 )(R 19 )—, R is selected from the group consisting of R 6 -phenyl, and R 6 -naphthyl R 1 is selected from the group consisting of hydrogen, alkyl, and alkenyl; R 2 is selected from the group consisting of R 3 is selected from the group consisting of R 6 -phenyl, R 6 -heteroaryl and R 6 -naphthyl; R 4 is selected from the group consisting of hydrogen, alkyl, fluoroalkyl, cyclopropylmethyl, —CH 2 CH 2 OH, —CH 2 CH 2 Oalkyl, —CH 2 C(O)—O-alkyl, —CH 2 C(O)NH 2 , —CH 2 C(O)—NHalkyl, and —CH 2 C(O)—N(alkyl) 2 ; R 5 is selected from the group consisting of hydrogen and alkyl; R 6 is 1 to 3 substituents independently selected from the group consisting of hydrogen, halogen, alkyl, alkoxy, —CF 3 , CF 3 O—, CH 3 C(O)—, —CN, CH 3 SO 2 —, CF 3 SO 2 —, R 14 -phenyl, R 14 -benzyl, CH 3 C(═NOCH 3 )—, CH 3 C(═NOCH 2 CH 3 )—, —NH 2 , —NHCOCF 3 , NHCONHalkyl, —NHC(O)alkyl, —NHS(O 2 )alkyl, 5-membered heteroaryl and wherein W is —O—, —NH— or —N(CH 3 )—; each R 7 and R 8 is independently selected from the group consisting of hydrogen, alkyl, haloalkyl, halogen, —NR 11 R 12 , —OH, —CF 3 , —O-alkyl, —O-acyl, and —O-haloalkyl; R 9 is selected from the group of consisting of hydrogen, alkyl, haloalkyl, cycloalkyl, aryl, acyl, heteroaryl, arylalkyl-, and heterocyclyl; R 11 , R 12 , each R 13 , and each R 14 , R 15 , and R 16 are independently selected from the group consisting of hydrogen and alkyl; R 19 is selected from the group consisting of R 6 -phenyl, R 6 -heteroaryl, R 6 -naphthyl, cycloalkyl, cycloalkylalkyl, and alkoxyalkyl; R 34 is R 35 O—; and R 35 is selected from the group consisting of H, alkyl, haloalkyl, cycloalkyl, heterocyclyl, aralkyl, alkylaryl, aryl, and heteroaryl.