Patent ID: 7442802

Claim:
A compound of Formula (I), (II) or a pharmaceutically acceptable salt thereof; wherein the compound of Formula (I) is: wherein: R 1 is —S(O) 2 —CH 3 ; R 1 ′ at each occurrence is independently a hydrogen, a halogen, a methyl or CH 2 OH; R 2 is a substituted lower alkyl group, a cycloalkyl group, an aryl group or a heteroaryl; R 3 is: (a) —(C(R 4 )(R′ 4 )) k —Y—(C(R 4 )(R′ 4 )) n —O—V; (b) —C(Z)-(C(R 4 )(R′ 4 )) k —O—V; (c) —C(Z)-(C(R 4 )(R′ 4 )) k —Y—(C(R 4 )(R′ 4 )) n —O—V; (d) —(C(R 4 )(R′ 4 )) k —Y—(C(R 4 )(R′ 4 )) n —C(Z)—(C(R 4 )(R′ 4 )) n —O—V; (e) —(C(R 4 )(R′ 4 )) k —CH═CH—(C(R 4 )(R′ 4 )) p —O—V; (g) —(C(R 4 )(R′ 4 )) n —W-Q-(C(R 4 )(R′ 4 )) k —O—V; (h) —(C(Z)-W-Q-(C(R 4 )(R′ 4 ) k —O—V; (i) —C(O)—N(R i )—O—(C(R 4 )(R′ 4 ) n —O—V; (j) —(C(R 4 )(R′ 4 )) k —C≡C—(C(R 4 )(R′ 4 )) p —O—V; (k) —(C(R 4 )(R′ 4 )) k —Y—(C(R 4 )(R′ 4 )) k —Y—(C(R 4 )(R′ 4 )) k —O—V; (l) —(C(R 4 )(R′ 4 )) p -E-N(R i )—O—W-Q-(C(R 4 )(R′ 4 ) k —O—V; (m) —(C(R 4 )(R′ 4 )) p -E-N(R i )—O—(C(R 4 )(R′ 4 ) k —O—V; (n) —(C(R 4 )(R′ 4 )) p —N(R i )—O—(C(R 4 )(R′ 4 ) k —O—V; (o) —(C(R 4 )(R′ 4 )) p —O—N(R i )—(C(R 4 )(R′ 4 ) k —O—V; (p) —(C(R 4 )(R′ 4 )) p —O—N(R i )-E-(C(R 4 )(R′ 4 ) k —O—V; or (q) —(C(R 4 )(R′ 4 )) p —O—N(R i )-E-W-Q-(C(R 4 )(R′ 4 ) k —O—V; R 4 and R′ 4 at each occurrence are independently a hydrogen, a halogen, a lower alkyl group, or an alkoxy group; V is —NO, —NO 2 , or a hydrogen; Y at each occurrence is independently an oxygen,—S(O) o — or —N(R a )R i —; Z is an oxo, a thial, an oxime or a hydrazone; Q is Y or a covalent bond; W at each occurrence is independently an aryl group, an alkylaryl group, a heterocyclic ring or an alkylheterocyclic ring; E is —C(O) or —S(O) o ; R a is a lone pair of electron, a hydrogen or a lower alkyl group; R i is a hydrogen, an alkyl, an aryl, an alkylcarboxylic acid, an arylcarboxylic acid, an alkylcarboxylic ester, an arylcarboxylic ester, an alkylcarboxamido, an arylcarboxamido, an alkylaryl, an alkylsulfinyl, an alkylsulfonyl, an arylsulfinyl, an arylsulfonyl, a sulfonamido, a carboxamido, a carboxylic ester, an aminoalkyl, an aminoaryl, —(C(R 4 )(R′ 4 )) n —O—V, or —(N 2 O 2 —) − •M + , wherein M + is an organic or inorganic cation; o is an integer from 0 to 2; k is an integer from 1 to 6; p at each occurrence is independently an integer from 0 to 10; n at each occurrence is independently an integer from 2 to 10; wherein the compound of Formula (II) is: wherein R 1, R 1 ′, R 2 and R 3 are as defined herein.