Patent ID: 8133898

Claim:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein Q is selected from the group consisting of —O—, —S—, and —NR 13 —; R 1 is selected from the group consisting of hydrogen, (C 1-10 )alkyl, (C 3-12 )cycloalkyl, (C 3-12 )heterocycloalkyl, aryl(C 1-10 )alkyl, (C 1-5 )heteroarylalkyl, (C 9-12 )bicycloaryl, (C 4-12 )heterobicycloaryl, carbonyl(C 1-3 )alkyl, thiocarbonyl(C 1-3 )alkyl, sulfonyl(C 1-3 )alkyl, sulfinyl(C 1-3 )alkyl, imino(C 1-3 )alkyl, amino, aryl, heteroaryl, hydroxy, alkoxy, aryloxy, heteroaryloxy, alkenyl, alkynyl, carbonyl group, cyano, imino group, sulfonyl group and sulfinyl group, each substituted or unsubstituted; R 2 is selected from the group consisting of amino(C 1-6 )alkyl, (C 3-12 )heterocycloalkyl, (C 4-12 )heterobicycloaryl, heteroaryl, and cyano, each substituted or unsubstituted; R 5 and R 7 are each independently selected from the group consisting of hydrogen, amino, sulfonamido, (C 1-10 )alkyl, (C 3-12 )cycloalkyl, (C 3-12 )heterocycloalkyl, aryl(C 1-10 )alkyl, heteroaryl(C 1-5 )alkyl, (C 9-12 )bicycloaryl, (C 4-12 )heterobicycloaryl, (C 3-12 )cycloalkyl(C 1-10 )alkyl, carbonyl(C 1-3 )alkyl, thiocarbonyl(C 1-3 )alkyl, sulfonyl(C 1-3 )alkyl, sulfinyl(C 1-3 )alkyl, imino(C 1-3 )alkyl, aryl, heteroaryl, hydroxy, alkoxy, aryloxy, heteroaryloxy, carbonyl group, imino group, sulfonyl group and sulfinyl group, each substituted or unsubstituted; R 12 is selected from the group consisting of (C 3-10 )alkyl, phenyl, phenylalkyl, naphthylalkyl, each substituted or unsubstituted; and R 13 is selected from the group consisting of hydrogen, (C 1-10 )haloalkyl, amino, thio, (C 1-10 )alkyl, (C 3-12 )cycloalkyl, (C 3-12 )heterocycloalkyl, aryl(C 1-10 )alkyl, heteroaryl(C 1-5 )alkyl, (C 9-12 )bicycloaryl, (C 4-12 )heterobicycloaryl, carbonyl(C 1-3 )alkyl, thiocarbonyl(C 1-3 )alkyl, sulfonyl(C 1-3 )alkyl, sulfinyl(C 1-3 )alkyl, imino(C 1-3 )alkyl, aryl, heteroaryl, hydroxy, alkoxy, aryloxy, heteroaryloxy, and imino group, each substituted or unsubstituted.