Patent ID: 8916546

Claim:
A method of treating ulcerative colitis in a mammal requiring such treatment, comprising administering to said mammal: a) orally, at least once daily, from about 100 mg to about 1000 mg of R-dihydro-lipoic acid and pharmaceutically acceptable salts thereof; and b) rectally an enema comprising: i) from about 500 mg to about 5000 mg of 5 ASA; ii) from about 0.5 mg to about 10 mg of budesonide; iii) from about 10 to about 1000 mg of cromolyn sodium; and iv) from about 5 ml to about 50 ml of a 1 molar short chain fatty acid solution, wherein the short chain fatty acid is sodium butyrate; and c) allowing the contents of the enema to be retained for at least about 4 hours.