Patent ID: 8748453

Claim:
A compound of Formula I: or a pharmaceutically acceptable salt, or solvate thereof, wherein R 1 and R 2 are independently selected from hydrogen, deuterium, halogen, trifluoromethyl, optionally substituted alkoxy, optionally substituted deuterated alkoxy and optionally substituted aminocarbonyl; X is C—CN; R 3 to R 6 are independently hydrogen (H) or deuterium (D); R 7 -R 10 are independently selected from hydrogen, deuterium, CH 3 , CD 3 , CH 2 D, CHD 2 , halogen, cyano, trifluoromethyl, optionally substituted alkoxy, optionally substituted deuterated alkoxy, optionally substituted C 2 -C 6 alkynyl and optionally substituted deuterated C 2 -C 6 alkynyl; and R 11 is hydrogen, deuterium, halogen, trifluoromethyl, optionally substituted alkoxy, optionally substituted deuterated alkoxy, optionally substituted aminocarbonyl, or urea; provided that R 1 to R 11 contain at least one deuterium atom.