Patent ID: 7709496

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 is hydrogen; fluorine; or chlorine; R 2 is hydrogen; fluorine; chlorine; or CN; A is CR 3 R 4 ; R 3 is hydrogen; R 4 is hydrogen or hydroxyl; W 1 is CR 5 or N; R 5 is hydrogen or hydroxyl; R 6 is hydrogen, (C 1-6 )alkyl; fluorine; chlorine; NR 1a R 1a′ ; (C 1-6 )alkylNR 1a R 1a′ ; (C 1-6 )alkoxy; (C 1-6 )alkyl(C 1-6 )alkoxy; (C 1-6 )hydroxyalkyl; hydroxyl; aryl; heteroaryl; heterocyclyl; (C 1-6 )aralkyl; thiol; (C 1-6 )alkylthio; C(═O)NR 1a R 1a′ ; (C 1-6 )alkylC(═O)NR 1a R 1a′ ; C(═O)R 1b ; (C 1-6 )alkyl(C═O)R 1b ; CO 2 R 1b ; or (C 1-6 )alkylCO 2 R 1b ; each R 1a and R 1a′ are independently hydrogen; acyl; (C 1-6 )alkyl; aryl; heteroaryl; or together with the nitrogen they are attached form an aziridine, azetidine, pyrrolidine, piperidine or hexamethyleneimine ring (wherein said aziridine, azetidine, pyrrolidine, piperidine or hexamethyleneimine ring is optionally substituted with 1 to 3 substitutents selected from halogen, (C 1-6 )alkyl, hydroxyl or aryl); each R 1b is independently hydrogen; (C 1-6 )alkyl; aryl; or heteroaryl; R 7 is hydrogen; (C 1-6 )alkyl(C 1-6 )alkoxy; (C 1-6 )alkylNR 1a R 1a′ ; or (C 1-6 )alkyl; R 8 is represented by the following structure: R 10 , R 12 and R 13 are at each occurrence independently selected from the group consisting of: H; (C 1-4 )alkylthio; halo; (C 1-4 )alkyl; (C 2-4 )alkenyl; hydroxy; hydroxy(C 1-4 )alkyl; mercapto(C 1-4 )alkyl; (C 1-4 )alkoxy; trifluoromethoxy; nitro; cyano; carboxy; and amino or aminocarbonyl unsubstituted or substituted by (C 1-4 )alkyl; and where U is C(═O); SO 2 ; or CH 2; “acyl” is C(═O) (C 1-13 )alkyl or C(═O)aryl; and “aryl” is optionally substituted phenyl or naphthyl.