Patent ID: 7371771

Claim:
A compound of formula I: wherein R 4 is selected from: X represents H, halogen, CN or methyl; R 1 represents H or C 1-4 alkyl which is optionally substituted with OH or C 1-4 alkoxy; R 2 and R 3 together with the nitrogen to which they are mutually attached complete a monocyclic heterocyclic ring system of 5-10 ring atoms selected from C, N, O and S, said ring system optionally having an additional benzene or heteroaryl ring fused thereto, said heterocyclic system and optional fused ring bearing 0-3 substituents independently selected from halogen, oxo, NO 2 , CN, R 12 , Ar, ArCH 2 O, ArO, ArOCH 2 , —OR 11 , —SR 11 , —SO 2 R 12 , —COR 11 , —CO 2 R 11 , —CON(R 11 ) 2 , —OCOR 12 , —N(R 11 ) 2 and —NR 11 COR 12 ; and when R 1 completes a ring with R 2 , R 3 represents H, C 1-6 alkyl, C 2-6 acyl, C 2-6 alkenyl or benzyl; m is 0 or 1, with the proviso that when m is 1 neither R 2 nor R 3 is H and R 3 is not acyl, and that m is 1 when X and R 1 are both H; R 11 represents H or R 12 ; R 12 represents C 1-6 alkyl which optionally bears up to 3 halogen substituents or one substituent selected from CN, OH, C 1-4 alkoxy and C 1-4 alkoxycarbonyl; R 14 represents H or C 1-6 alkyl, C 3-7 cycloalkyl, C 3-6 cycloalkylC 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, phenyl or benzyl, any of which optionally bear up to 3 halogen substituents or one substituent selected from CN, NO 2 , OH, C 1-4 alkoxy, CO 2 H, C 1-4 alkoxycarbonyl, C 2-6 acyl, C 2-6 acyloxy amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino, C 2-6 acylamino, carbamoyl, C 1-4 alkylcarbamoyl and di(C 1-4 alkyl)carbamoyl; and Ar represents phenyl or heteroaryl either of which optionally bears up to 3 substituents independently selected from halogen, CF 3 , NO 2 , CN, OCF 3 , C 1-6 alkyl and C 1-6 alkoxy; or a pharmaceutically acceptable salt thereof.