Patent ID: 8835647

Claim:
A process for preparing 2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide in a solid crystalline form, wherein the crystalline form is Form I which, when measured at about 25° C. with radiation at 1.54178 Å, is characterized by a powder diffraction pattern having respective 2θ values of about 9.9°, 11.0° and 11.8° and one or more than one additional peaks having respective 2θ values of about 14.6°, 15.2°, 18.2°, 19.6°, 20.3°, 21.3°, 22.5°, 22.8°, 24.7°, 28.5°, and 29.1°, comprising a) providing a mixture comprising 2-((R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide and 2-propanol, wherein the 2-((R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide is dissolved in the 2-propanol; b) causing 2-((R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide Form 1 to exist in the mixture between about 0° C. and ambient temperature; and c) isolating 2-((R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide in a solid crystalline form.