Patent ID: 7846923

Claim:
A compound of Formula I: in which: A is selected from CR 5a and N; wherein R 5a is selected from hydrogen, C 1-6 alkyl and C 3-8 heterocycloalkyl-C 0-4 alkyl; wherein said heterocycloalkyl of R 5a is optionally substituted with C 1-6 alkyl; B is selected from CR 5b and N; wherein R 5b is selected from hydrogen and C 1-6 alkyl; n is selected from 1, 2, 3 and 4; m is selected from 0 and 1; R 1 is selected from hydrogen and —X 1 C(O)OR 6 ; wherein X 1 is selected from a bond and C 1-6 alkylene; and R 6 is selected from hydrogen and C 1-6 alkyl; R 2 is selected from C 1-6 alkyl, C 3-8 heterocycloalkyl-C 0-4 alkyl, C 3-12 cycloalkyl-C 0-4 alkyl and —X 2 NR 7a R 7b ; wherein X 2 is selected from a bond and C 1-6 alkylene; and R 7a and R 7b are independently selected from hydrogen and C 1-6 alkyl; wherein any heterocycloalkyl of R 2 is optionally substituted with C 1-6 alkyl; R 3 is selected from halo, C 1-6 alkyl and C 1-6 alkoxy; R 4 is selected from —OR 9 , —NR 8a C(O)NR 8b R 9 , —C(O)NR 8b R 9 , —NR 8a C(O)R 9 , —C(O)OR 8a and —C(O)NR 8a X 3 OR 9 ; wherein X 3 is selected from a bond and C 1-6 alkylene; R 8a and R 8b are independently selected from hydrogen and C 1-6 alkyl; and R 9 is selected from C 1-6 alkyl, C 6-10 aryl-C 0-4 alkyl, C 3-12 cycloalkyl and C 1-10 heteroaryl; wherein any aryl, heteroaryl or cycloalkyl of R 9 is optionally substituted with 1 to 3 radicals independently selected from halo-substituted-C 1-6 alkyl and C 3-8 heterocycloalkyl optionally substituted with C 1-6 alkyl; or R 8b and R 9 together with the nitrogen atom to which R 8 and R 9 are attached form C 1-10 heterocycloalkyl optionally substituted with C 1-6 alkyl; or a pharmaceutical salt thereof.