Patent ID: 7923560

Claim:
An IRM-support complex comprising an IRM compound that is a TLR agonist selected from the group consisting of TLR6, TLR7, TLR8, and combinations thereof, and selected from the group consisting of imidazoquinoline amines; tetrahydroimidazoquinoline amines; and imidazopyridine amines; 1,2-bridged imidazoquinoline amines; 6,7-fused cycloalkylimidazopyridine amines; imidazonaphthyridine amines; tetrahydroimidazonaphthyridine amines; oxazoloquinoline amines; thiazoloquinoline amines; oxazolopyridine amines; thiazolopyridine amines; oxazolonaphthyridine amines; thiazolonaphthyridine amines; 1H-imidazo dimers fused to pyridine amines, quinoline amines, tetrahydroquinoline amines, naphthyridine amines, or tetrahydronaphthyridine amines; and combinations thereof; covalently bonded to a macromolecular support material wherein the macromolecular support material has an average largest dimension of at least 1 nm.