Patent ID: 7459562

Claim:
A compound having Formula II: or an enantiomer, diastereomer, or pharmaceutically acceptable salt thereof wherein: each R 2 is independently H, halogen, OR 5 , NR 6 R 7 , alkyl, and/or haloalkyl; B is O, S, SO, or SO 2 ; W is C; X is C; n is zero to 4; R 3 , R 5 , R 6 , and R 7 are independently H and/or alkyl; R 4 is a monocyclic 5- to 6-membered nitrogen containing heteroaryl, optionally substituted with one or more substituents selected from alkyl, hydroxy, alkoxy, halogen, phenyl, fluorophenyl, ═O, and benzyl, provided that (a) if R 4 is monocyclic ring pyridyl, R 4 is monocyclic ring not substituted with both hydroxy and methoxy; and (b) if R 4 is monocyclic ring pyrimidinyl, it is not substituted with ═O; R 16 , R 17 , R 18 , and R 19 are H, halogen, NR 30 R 31 , OR 32 , alkyl, hydroxyalkyl, pyridyl, alkenyl, alkynyl, and/or alkynyl substituted with —OH, —NH 2 , —N(alkyl) 2 , or pyridyl, phenyl, phenyl substituted with aminoalkyl; R 30 and R 31 are independently selected from H, alkyl, aminoalkyl, benzyl, methoxybenzyl, phenyl, fluorophenyl, and pyridyl; and R 32 is H or alkyl.