Patent ID: 8772526

Claim:
A method for the preparation of a glycerol dithiocarbamate (GDTC) of formula R 1 —C(OH)—CH 2 —S—C—(S)—NR 2 R 3 (I) or R′ 1 R′ 2 —N—C(S)—S—CH 2 —CH(OH)—CH 2 —S—C(S)—NR 2 R 3 (I′) or R 2 R 3 —N—C(S)—S—CH 2 —CH(OH)—CH 2 —O—CH 2 —CH(OH)—CH 2 —S—C(S)—NR 2 R 3 (I″) in which R 1 represents H; a linear or branched C 1 -C 22 alkyl radical or a C 3 -C 16 cyclo-alkyl radical optionally substituted with one or more hydroxy, —O-alkyl, thiohydroxy or —S-alkyl groups, the chain of the alkyl radical optionally being interrupted by one or more O, N or S heteroatoms; a linear or branched C 2 -C 22 alkenyl radical mono- or poly-unsaturated; a C 2 -C 6 alkynyl radical; a C 6 -C 10 aryl radical; or a C 7 to C 22 arylalkyl radical; and R 2 and R 3 , independently of each other, represent H; a linear or branched C 1 -C 22 alkyl radical or a C 3 -C 16 cyclo-alkyl radical optionally substituted with one or more hydroxy, —O-alkyl, thiohydroxy or —S-alkyl groups, the chain of the alkyl radical optionally being interrupted by one or more O, N or S heteroatoms; a linear or branched, mono- or poly-unsaturated C 2 -C 22 alkenyl radical; a C 2 -C 6 alkynyl radical; a C 6 -C 16 aryl radical; or a C 7 to C 22 arylalkyl radical; or R 2 and R 3 together with the nitrogen atom to which they are bonded form a cycloamino group; R′ 1 and R′ 2 have the same meanings as R 2 and R 3 , wherein said method comprises implementing a reaction medium with a carbon disulphide CS 2 and a primary or secondary amine NHR 2 R 3 wherein R 2 and R 3 are as defined above, said reaction medium comprising (a) a glycerol type polyol of formula R 1 —CH(OH)—CH 2 OH (II) in which R 1 has the same meanings as above and a carbonate selected from the group consisting of diethyl carbonate, dimethyl carbonate, ethylene carbonate and propylene carbonate in the presence of a basic catalyst, or (b) a cyclic carbonate comprising five ring members having the following formula (IV): wherein R 1 has the same meanings as above, or (c) a cyclic carbonate comprising five ring members of formula in which R′ 1 and R′ 2 , independently of each other, represent H; a linear or branched C 1 -C 22 alkyl radical or a C 3 -C 16 cyclo-alkyl radical optionally substituted with one or more hydroxy, —O-alkyl, thiohydroxy or —S-alkyl groups, the chain of the alkyl radical optionally being interrupted by one or more O, N or S heteroatoms; a linear or branched, mono- or poly-unsaturated C 2 -C 22 alkenyl radical; a C 2 -C 6 alkynyl radical; a C 6 -C 16 aryl radical; or a C 7 to C 22 arylalkyl radical; or R′ 1 and R′ 2 together with the nitrogen atom to which they are bonded form a cycloamino group; or (d) a cyclic polycarbonate comprising five ring members; and recovering the formed GDTC.