Patent ID: 7214502

Claim:
A method for identifying a compound capable of modulating cellular proliferation comprising: a) contacting a test compound with a sample comprising a polypeptide selected from the group consisting of: i) a polypeptide comprising an amino acid sequence which is at least 95% identical to the amino acid sequence of SEQ ID NO:5, wherein said polypeptide has kinase activity; ii) a polypeptide which is encoded by a nucleic acid molecule comprising a nucleotide sequence which is at least 95% identical to a nucleic acid comprising the nucleotide sequence of SEQ ID NO:4 or 6, wherein said polypeptide has kinase activity; iii) a polypeptide which is encoded by a nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:4 or 6; and iv) a polypeptide comprising the amino acid sequence of SEQ ID NO:5; b) assaying the ability of the test compound to modulate the kinase activity of the polypeptide; c) contacting cells which express the polypeptide with the compound identified in b); and d) determining the effect of the compound on cellular proliferation; thereby identifying a compound capable of modulating cellular proliferation.