Patent ID: 8173672

Claim:
A compound of formula (I) and pharmaceutically acceptable salts thereof, wherein Q is selected from the group consisting of X 1 and X 2 are CR 2 ; X 3 is —CR 2 ═CR 2 —, R 1 is optionally present at one or more of the cyclic carbon atoms of the N-heterocyclic ring, and each R 1 is selected from the group consisting of (1) —C 1-6 alkyl, (2) —C 3-8 cycloalkyl, (3) —C 6-10 aryl, (4) heteroaryl, or (5) —(═O)—OR 6A , wherein the alkyl, aryl or heteraryl moiety of R 1 is optionally substituted by one or more (a) halogen, (b) hydroxy, (c) —C 1-6 alkyl, wherein said alkyl is optionally substituted with one or more halogen, (d) —CN, (e) —C 6-10 aryl, (f) —NHC(═O)—OR 6A ; R 2 is selected from the group consisting of (1) hydrogen, (2) —C 1-6 alkyl, (3) —OC 1-6 alkyl, (4) —NO 2 , (5) S(O) p R 6A , (6) halogen, (7) hydroxy (8) —CN, (9) —NR 6A R 6B , (10) —C 6-10 aryl, (11) heteroaryl, or (12) —C(═O)—OR 6A , wherein the alkyl, aryl or heteraryl moiety of R 2 is optionally substituted by one or more (a) halogen, (b) hydroxy, (c) —C 1-6 alkyl, wherein said alkyl is optionally substituted with one or more halogen, (d) —CN, (e) —C 6-10 aryl, R 4 is selected from the group consisting of (1) hydrogen, (2) —C 1-6 alkyl, and (3) —CH 2 -aryl, wherein said alkyl or aryl moiety of R 4 is optionally substituted with one or more (a) halogen, (b) cyano, and (c) —O—C 1-6 alkyl, wherein said alkyl is optionally substituted with one or more halo; R 6A and R 6B are independently selected from the group consisting of (1) hydrogen, (2) —C 1-6 alkyl, (3) —(CH 2 ) m -aryl, or wherein said alkyl or aryl moiety of R 6A or R 6B is optionally substituted with one or more (a) halogen, (b) cyano, and (c) —O—C 1-6 alkyl, wherein said alkyl is optionally substituted with one or more halo; m is 0 or 1; and p is 0, 1 or 2.