Patent ID: 7582650

Claim:
A compound of Formula 1 wherein: R 1 is hydroxy, aminocarbonyl, hydroxyamidino, formylamino; C 1-4 alkanylaminocarbonyl; phenyl-aminocarbonyl; phenyl(C 1-4 )alkanylaminocarbonyl; and naphthyl- and phenyl- amino wherein the naphthyl and phenyl are optionally substituted with one to two substitutents independently selected from the group consisting of C 1-4 alkanyl, C 1-4 alkoxy, halogen, and hydroxy; or pyridinylamino; R 2 is selected from the group consisting of hydrogen, C 1-4 alkanyl, C 2-8 alkenyl, C 2-8 alkynyl, C 3-8 cycloalkanyl(C 1-4 )alkanyl, C 1-4 alkanyloxy(C 1-4 )alkanyl, C 1-4 alkanylthio(C 1-4 )alkanyl, hydroxyC 1-4 alkanyl, thioformyl, phenylimino(C 1-4 )alkanyl, phenyl(C 1-4 )alkanyl, and heteroaryl(C 1-4 )alkanyl wherein heteroaryl is selected from the group consisting of benzo [1,3 ]dioxolyl, imidazolyl, furanyl, pyridinyl, thienyl, indolyl, indolinyl, isoquinolinyl, pyrazinyl, pyrazolyl, pyridazinyl, pyrimidinyl, pyrrolyl, quinolinyl, benzothiophenyl, tetrazolyl; wherein phenyl and heteroaryl are optionally substituted with one to three substituents independently selected from the group consisting of C 1-6 alkanyloxy and hydroxy; or optionally, when phenyl and heteroaryl are optionally substituted with two substituents attached to adjacent carbon atoms, the two substituents together form —O(CH 2 ) 1-3 O—; A is —(CH 2 ) 2 —; Y is O; and enantiomers, diastereomers, tautomers, or pharmaceutically acceptable salts thereof.