Patent ID: 8088806

Claim:
A method of relieving one or more symptoms of Hepatitis C Infection in a patient, comprising administering to a patient in need thereof, a therapeutically effective amount of a compound of the formula or pharmaceutically acceptable salt or hydrate thereof; wherein: R is 0 or one or more substituents independently chosen from halogen, hydroxyl, amino, cyano, nitro, C 1 -C 2 alkyl, C 1 -C 2 alkoxy, C 1 -C 2 haloalkyl, and C 1 -C 2 haloalkoxy; R 1 is one substituent independently chosen from C 4 -C 10 alkyl, C 2 -C io alkenyl, C 2 -C io alkynyl, C 4 -C io alkoxy, and a group-YZ, where Y is a bond, or Y is C 1 -C 10 alkyl optionally having 1 or 2 oxygen or nitrogen atoms within the alkyl chain; and Z is C 3 -C 7 cycloalkyl, phenyl, or (C 3 -C 7 cycloalkyl)C 0 -C 10 alkoxy, wherein each group listed in the definition of R 1 is substituted with 0 or one or more substituents independently chosen from: halogen, hydroxyl, amino, cyano, nitro, oxo, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, C 1 -C 2 haloalkyl, and C 1 -C 2 haloalkoxy; wherein there is an R 1 substituent in either the meta or para positions of the phenyl it substitutes; R 2 is pyridyl, which is substituted with 0 or one or more substituents independently chosen from halogen, hydroxyl, cyano, —C(O)NH 2 , C 1 -C 2 haloalkyl, C 1 -C 2 haloalkoxy, mono- and di-C 1 -C 6 alkylamino, mono- and di-(C 1 -C 4 alkyl)carboxamide, and mono- and di(C 1 -C 4 alkyl)sulfonamide, R 3 is hydrogen; and R 4 is hydrogen, halogen, cyano, trifluoromethyl or C 1 -C 2 alkyl.