Patent ID: 8030336

Claim:
A compound of formula I or a pharmaceutically acceptable salt or diastereomer thereof, wherein: A is NR 1 , where R 1 is H or C 1-4 alkyl; B is phenyl optionally substituted with 0-4 substituents independently selected from halogen, C 1-4 alkyl, CF 3 , CN, aryl, OH, OCF 3 , OC 1-4 alkyl, OC 2-5 alkylNR 2 R 3 , Oaryl, CO 2 R 2 , CONR 2 R 3 , NR 2 R 3 , NR 4 C 1-4 alkylNR 2 R 3 , NR 2 COR 3 , OC(O)NR 2 R 3 , NR 4 CONR 2 R 3 , and NR 2 SO 2 R 3 ; wherein R 2 and R 3 are each independently H, C 1-4 alkyl, aryl, or C 1-4 alkyl aryl; wherein R 4 is H or C 1-4 alkyl; and wherein R 5 is H or C 1-4 alkyl; Q is a bond when W is absent, and is C 1-4 alkyl when W is present; W is selected from H, C 1-4 alkyl, and C 2-6 alkenyl; where C 1-4 alkyl or C 2-6 alkenyl may be optionally substituted with C 1-4 alkyl, OH, OC 1-4 alkyl, NR 6 C(O)R 7 , CONR 6 R 7 , OR 6 , or NR 6 R 7 ; wherein R 6 and R 7 are each independently H, C 1-4 alkyl, C 1-4 alkyl cycloalkyl, or aryl, and Y is phenyl, optionally substituted with 0-3 substituents independently selected from halogen, C 1-4 alkyl, CF 3 , aryl, OH, OCF 3 , C 2-4 alkynyl, OC 1-4 alkyl, OC 2-5 alkylNR 9 R 10 , Oaryl, CONR 9 R 10 , C 1-4 alkylNR 9 R 10 , NR 11 C 1-4 alkylNR 9 R 10 , NR 9 COR 10 , NR 11 CONR 9 R 10 , and NR 9 SO 2 R 10 ; wherein R 9 and R 10 are each independently H, C 1-4 alkyl, aryl, or C 1-4 alkyl aryl; and wherein R 11 is H or C 1-4 alkyl.