Patent ID: 7473788

Claim:
A compound having the structure: wherein R 1 is H or OH, wherein R 3 is H or OH; and wherein R 2 is Cl or I and R 4 is H, (C 1 -C 10 ) alkyl, (C 2 -C 10 ) alkenyl, (C 2 -C 10 ) alkynyl, -A-Ar, -A-Z-Ar, —SO 2 —Ar, or -A-NR 6 , or —R 6 , where A is (C 1 -C 8 ) alkyl, (C 2 -C 8 ) alkenyl, (C 2 -C 8 )alkynyl, which is unsubstituted or substituted by a straight or branched alkyl chain group having 1 to 5 carbon atoms; Z is carbon, oxygen, sulfur or nitrogen; Ar is a phenyl group, a pyridyl group, a naphthyl group, a pyrimidyl group, or a quinolyl group, each of which may be unsubstituted or substituted by one to five substituents selected from the group consisting of hydrogen, halogen, a hydroxy group, a carboxylic acid group, substituted or unsubstituted (C 1 -C 10 ) alkyl, (C 2 -C 10 ) alkenyl, (C 2 -C 10 ) alkynyl, (C 1 -C 10 ) haloalkyl, (C 1 -C 10 ) alkoxy, (C 2 -C 10 ) alkenyloxy, (C 2 -C 10 ) alkynyloxy, (C 1 -C 10 ) haloalkoxy, a phenyl group, a phenoxy group, an aralkyl group, an aralkyloxy group, a substituted phenyl group, a substituted phenoxy group, a substituted aralkyl group, a substituted aralkyloxy group, —COR 6 , —CONR 6 R 6 , —CO 2 R 6 , —NHCOR 6 , —NH(OH), —N(OH)COR 6 , —CH 2 OR 6 , —OCH 2 CO 2 R 6 , —CH 2 SR 6 , —CH 2 NR 6 R 6 , —SR 6 , —OSR 6 , —NR 6 R 6 , —NR 6 SO 2 R 6 , where R 6 is hydrogen, (C 1 -C 10 ) alkyl, (C 3 -C 10 ) cycloalkyl, —SCX 3 in which X is a halogen, —CN, —NO 2 or -Z-A-Z′- in which Z and A are as defined above and Z′ represents carbon, oxygen, sulfur, or nitrogen; or wherein R 2 is OH or halogen and R 4 is (C 2 -C 10 ) alkenyl, (C 2 -C 10 ) alkynyl, -A-Ar, -A-Z-Ar, or -A-NR 6 where A is (C 2 -C 8 ) alkenyl, or (C 2 -C 8 )alkynyl, which is unsubstituted or substituted by a straight or branched alkyl chain group having 1 to 5 carbon atoms where R 6 is hydrogen, (C 1 -C 10 ) alkyl, (C 3 -C 10 ) cycloalkyl, —SCX 3 in which X is a halogen, —CN, —NO 2 or -Z-A-Z′- in which Z and A are as defined above and Z′ represents carbon, oxygen, sulfur, or nitrogen; or an optically pure enantiomer, or a tautomer, or a salt of the compound.