Patent ID: 7012078

Claim:
A compound of the formula wherein ring A is a fused 5-7 membered saturated or unsaturated ring wherein from zero to two of the ring members are heteroatoms selected, independently, from nitrogen, oxygen and sulfur, with the proviso that no two adjacent ring members can both be heteroatoms; X is oxygen or a bond; n is an integer from two to six; and R 1 and R 2 are selected, independently, from (C 1 -C 6 ) alkyl, aryl, tetrahydronaphthalene and aralkyl, wherein said aryl and the aryl moiety of said aralkyl is phenyl or naphthyl and the alkyl moiety is straight or branched and contains from 1 to 6 carbon atoms, and wherein said (C 1 -C 6 ) alkyl, said aryl, said tetrahydronaphthalene and the aryl moiety of said aralkyl may optionally be substituted with from one to three substituents that are selected, independently, from halo, nitro, hydroxy, cyano, amino, (C 1 -C 4 ) alkoxy, and (C 1 -C 4 ) alkylamino; or R 1 and R 2 form, together with the nitrogen to which they are attached, a piperazine, azetidine, piperidine or pyrrolidine ring or an azabicyclic ring containing from 6 to 14 ring members, from 1 to 3 of which are nitrogen and the rest of which are carbon; and wherein said piperazine, azetidine, piperidine and pyrrolidine rings may optionally be substituted with one or more substituents that are selected, independently, from (C 1 -C 6 )alkyl, amino, (C 1 -C 6 ) alkylamino, [di-(C 1 -C 6 )alkyl]amino, phenyl, substituted 5 to 6 membered heterocyclic rings containing from 1 to 4 rings nitrogen atoms, benzoyl, benzoylmethyl, benzylcarbonyl, phenylaminocarbonyl, phenylethyl and phenoxycarbonyl, and wherein the phenyl moieties of any of the foregoing substituents may optionally be substituted with one or more substituents that are selected; Independently, from halo, (C 1 -C 3 )alkyl, (C 1 -C 3 )alkoxy, nitro, amino, cyano, CF 3 and OCF 3 ; wherein, provided when X is oxygen and R 1 or R 2 is alkyl, R 1 or R 2 together with the nitrogen may be connected onto the (CH2) n group to form a ring of from 4 to 7 members; or the pharmaceutically acceptable salt of such compounds.