Patent ID: 8163280

Claim:
A method for treating a hyperproliferative disorder in which c-Met is expressed in a subject in need thereof, comprising the step of administering to said subject a human monoclonal antibody or an antigen-binding portion thereof that specifically binds to c-Met, wherein the heavy chain and light chain of said antibody comprise the heavy chain CDR1, CDR2 and CDR3 amino acid sequences and the light chain CDR1, CDR2 and CDR3 amino acid sequences, respectively, of an antibody selected from the group consisting of: 13.3.2; 9.1.2; 8.70.2; 8.90.3; 13.3.2H-E42K; 13.3.2H-E42K,S97T; 13.3.2H-S97T; 13.3.2L-A91T; 13.3.2H-E42K/13.3.2L-A91T; 13.3.2H-E42K,S97T/13.3.2L-A91T; and 13.3.2H-S97T/13.3.2L-A91T.