Patent ID: 7618973

Claim:
A compound of formula I wherein X is O or NH; R 1 is phenyl, optionally substituted with one, two or three halo, R 2 is H, C 1-4 alkyl or C 1-4 haloalkyl; R 3 and R 4 each are independently H, C 1-7 alkyl, optionally substituted with one or more halo, cyano, or hydroxy, C 1-7 alkoxy, optionally substituted with one or more halo, CN, halo, NO 2 , —C(O)—R a , wherein R a is hydroxy, C 1-7 alkoxy, C 1-7 alkyl, phenoxy or phenyl, —C(O)—NR b R c , wherein R b and R c are each independently H, C 1-7 alkyl, optionally substituted with one or more halo, hydroxy, or cyano, —(CH 2 ) z —C 3-7 cycloalkyl, optionally substituted by one or more B, and z is 0, 1, 2, 3 or 4, —(CH 2 ) y -heterocyclyl, wherein y is 0, 1, 2, 3 or 4, and wherein heterocyclyl is optionally substituted by one or more A R b and R c together with the nitrogen to which they are bound form a heterocyclyl moiety, optionally substituted with one or more A, or or R 3 and R 4 together form an annelated benzo ring, the benzo ring is optionally substituted by one or more E; A is hydroxy, oxo, C 1-7 alkyl, C 1-7 alkoxy, C 1-7 haloalkyl, C 1-7 hydroxyalkyl, halo, or CN; B is halo, hydroxy, CN, C 1-4 alkyl, or C 1-4 haloalkyl; E is halo, CN, NO 2 , hydroxy, C 1-7 alkyl, C 1-7 alkoxy, C 1-7 haloalkyl, C 1-7 hydroxyalkyl, C 1-7 cyanoalkyl, C 1-7 haloalkoxy, or C 3-7 cycloalkyl, or a pharmaceutically acceptable salt thereof.