Patent ID: 7585874

Claim:
An aryl-isoxazol-4-yl-imidazo[1,2-a]pyridine derivative of formula I wherein R 1 is hydrogen, halogen, hydroxy, lower alkyl, benzyloxy or —O—(CH 2 )—(CO)-5 or 6 membered heteroaryl optionally substituted by aryl or by lower alkyl; R 2 is hydrogen, halogen, lower alkyl, lower alkynyl, amino, —NHC(O)—R a or —(CO)—R a ; R 3 is hydrogen, halogen, cyano, lower alkyl, lower alkynyl, amino, —NHC(O)—R a , —(CO)—R a , -5 or 6-membered heterocycloalkyl in the 1-position, optionally substituted by ═O or is a -5 or 6-membered heteroaryl in the 1-position; R 4 is hydrogen or -5 or 6-membered heteroaryl; R 5 is lower alkyl or cycloalkyl; R a is lower alkoxy or NR′R″, wherein R′ and R″ are each independently hydrogen, lower alkyl optionally substituted by hydroxy, lower alkynyl, —(CH 2 ) n -cycloalkyl, —(CH 2 ) n -5 or 6-membered heterocycloalkyl or —(CH 2 ) n -5 or 6-membered heteroaryl; and n is 0 to 3; or a pharmaceutically acceptable acid addition salt thereof.