Patent ID: 8222277

Claim:
A method for treating an inflammatory disease in a patient in need thereof comprising administering to the patient a therapeutically effective amount of a composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier; wherein the compound of Formula (I) is: wherein: R m is a hydrogen or a lower alkyl group; R n is: s is an integer of 0 or 1; X is —Y—(CR 4 R 4 ′) o —C(R 4 )(ONO 2 )—(CR 4 R 4 ′) q -(T) o -(W) q -(T) o -(CR 4 R 4 ′) o —R 5 ; R 4 and R 4 ′ at each occurrence are independently a hydrogen, lower alkyl group, —OH, —CH 2 OH, —ONO 2 , —NO 2 or —CH 2 ONO 2 ; or R 4 and R 4 ′ taken together with the carbon atom to which they are attached are a cycloalkyl group or a heterocyclic ring; W is a covalent bond or a carbonyl group; T at each occurrence is independently an oxygen, (S(O) o ) o or NR j ; R j is a hydrogen, an alkyl group, an aryl group, a heterocyclic ring, an alkylcarbonyl group, an alkylaryl group, an alkylsulfinyl group, an alkylsulfonyl group, an arylsulfinyl group, an arylsulfonyl group, a sulfonamido group, a N-alkylsulfonamido group, a N,N-diarylsulfonamido group, a N-arylsulfonamido group, a N-alkyl-N-arylsulfonamido group, a carboxamido group or a hydroxyl group; q at each occurrence is independently an integer from 1 to 3; o at each occurrence is independently an integer from 0 to 2; Y is oxygen or sulfur (—S—); and R 5 is a hydrogen, a hydroxyl group, an alkyl group, an aryl group, an alkylsulfonyl group, an arylsulfonyl group, a carboxylic ester, an alkylcarbonyl group, an arylcarbonyl group, a carboxamido group, an alkoxyalkyl group, an alkoxyaryl group, a cycloalkyl group or a heterocyclic ring.