Patent ID: 8487090

Claim:
A preparation process of an aqueous solution of a medicinal composition comprising a 20(R)-ginsenoside Rg3, comprising step 1, step 2, step 3 and step 4, wherein step 1 comprises dissolving the 20(R)-ginsenoside Rg3 in a mixture of an organic solvent, and forming a solution comprising 0.1˜5% the ginsenoside; wherein step 2 comprises dissolving adjuvant A in water, and forming an aqueous solution comprising 0.1˜30 wt % adjuvant A, wherein the adjuvant A is selected from deoxycholic acid, deoxycholic acid sodium or sodium dodecylsulphate (SDS); wherein step 3 comprises adding all the ginsenoside solution obtained in step 1 in whole into the aqueous solution of adjuvant A obtained in step 2 at 40˜100° C. where the ratio of ginsenoside to Adjuvant A=1:1˜300, and stirring the mixture for 0.1˜3 hour to obtain a clear solution; and wherein step 4 comprises removing the solvent from the clear solution obtained in step 3 at temperature of 80˜100° C. under a vacuum of 0.01˜0.08 MPa until the solution reaches a near dryness state of about ⅔ of the original volume, adding water to the solution of the near dryness state to the original volume prior to removing the solvent, removing the solvent at temperature of 80˜100° C. under a vacuum of 0.01˜0.08 MPa into near dryness; repeating the previous procedure twice to form a near dryness material, and adding injection water or purified water into the near dryness material to dissolve the material to form a solution.