Patent ID: 7910321

Claim:
A method for determining the level of a TR2 polypeptide in a biological sample from an individual comprising: (a) contacting the biological sample from the individual with an antibody or fragment thereof which binds to said polypeptide; (b) allowing a complex to form between said polypeptide and said antibody or fragment thereof; and (c) detecting said complex; wherein said TR2 polypeptide has an amino acid sequence selected from the group consisting of: (i) the amino acid sequence at positions from about −36 to about 247 in SEQ ID NO:2; (ii) the amino acid sequence at positions from about −35 to about 247 in SEQ ID NO:2; (iii) the amino acid sequence at positions from about 1 to about 247 in SEQ ID NO:2; (iv) the amino acid sequence encoded by the cDNA clone contained in ATCC™ Deposit Number 97059; (v) the amino acid sequence of the mature TR2 polypeptide encoded by the cDNA clone contained in ATCC™ Deposit Number 97059; (vi) the amino acid sequence at positions from about 1 to about 164 in SEQ ID NO:2; (vii) the amino acid sequence at positions from about −36 to about 149 in SEQ ID NO:5; (viii) the amino acid sequence at positions from about −35 to about 149 in SEQ ID NO:5; (ix) the amino acid sequence at positions from about 1 to about 149 in SEQ ID NO:5; (x) the amino acid sequence encoded by the cDNA clone contained in ATCC™ Deposit Number 97058; (xi) the amino acid sequence of the mature TR2 polypeptide encoded by the cDNA clone contained in ATCC™ Deposit Number 97058; (xii) the amino acid sequence in SEQ ID NO:8; (xiii) the amino acid sequence at positions from about 2 to about 136 in SEQ ID NO:8; and (xiv) the amino acid sequence encoded by the cDNA clone contained in ATCC™ Deposit Number 97057.