Patent ID: 8236963

Claim:
A compound according to Formula (I′) wherein: R 1 is selected from the group consisting of hydrogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, halo-C 1 -C 6 -alkyl, halo-C 1 -C 6 -alkoxy, halogen, aryl and heteroaryl; m is an integer selected from 0, 1, 2, 3 or 4; R 2 is either C 3 -C 6 -alkyl or A; wherein A is selected from the group consisting of A1, A2, A3, A4, A5 and A6: with each n being an integer independently selected from 1, 2, 3 or 4; wherein R 4 is selected from the group consisting of C 2 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -heterocycloalkyl, aryl and heteroaryl; each R 4 may optionally be substituted independently with one or more groups R 6 ; each R 6 is independently selected from the group consisting of C 1 -C 6 -alkyl, alkoxy, alkoxycarbonyl, aryl, aryl C 1 -C 6 -alkyl, heteroaryl, substituted or unsubstituted heteroaryl C 1 -C 6 -alkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -heterocycloalkyl, carboxyl, cyano, halogen, hydroxy, amino, aminocarbonyl, acylamino, nitro, sulfoxy, sulfonyl, sulfonylamine, aminosulfonyl and trihalo-C 1 -C 6 -alkyl; R 7 is either hydrogen or C 1 -C 6 -alkyl; R 3 is B, wherein B is: ←(CH 2 ) n -R 5 with n being an integer independently selected from 1, 2, 3 or 4; wherein R 5 is carboxy; X is either CH 2 or NH; each Y is independently either C(O) or CH 2 ; and z is either C(O) or CHR 7 ; as well as its geometrical isomers, optically active forms as enantiomers, diastereomers, its racemate forms, or pharmaceutically acceptable salts thereof.