Patent ID: 7858114

Claim:
A percutaneous absorption preparation of donepezil used as a plaster to skin, which comprises at least an adherent layer, an intermediate membrane, and a drug reservoir layer sequentially from the side which is plastered on skin, wherein said drug reservoir layer comprises donepezil or a salt thereof; a dialkylaminoalkyl (meth)acrylate-alkyl(meth)acrylate copolymer; a polyhydric alcohol selected from a sugar alcohol and a glycol; a carboxylic acid ester selected from an alkyl citrate ester and an alkyl sebacate ester; a sorbitan fatty acid ester; and a (meth)acrylate-vinyl ester copolymer, said intermediate membrane is a microporous membrane having pores which allow permeation of donepezil, and said adherent layer enables the plastering of the percutaneous absorption preparation to skin, is permeable to donepezil, and comprises a carboxylic acid ester selected from an alkyl citrate ester and an alkyl sebacate ester; a sorbitan fatty acid ester; and a (meth)acrylate-vinyl ester copolymer.