Patent ID: 7608400

Claim:
A method for detecting a single nucleotide polymorphism (SNP) associated with hereditary equine regional dermal asthenia (HERDA) phenotype in an equine, the method comprising: isolating from the equine a DNA molecule comprising a cyclophilin B (PPIB) sequence at least 95% identical to SEQ ID NO: 1 or an mRNA molecule transcribed from the PPIB sequence; and detecting a G to A substitution at position 115 counted from the start codon of the PPIB sequence; wherein the presence of a single copy of G to A substitution at position 115 of the PPIB sequence indicates that the equine is carrier for the SNP associated with HERDA and the presence of two copies of a G to A substitution at position 115 indicates that the animal is affected with HERDA.