Patent ID: 8921305

Claim:
A method for treating cancer comprising: administering to a cancer patient at least one Crotoxin dosage of from about 0.04 to about 0.32 mg/m 2 , the dosage being intravenously administered in an intra-patient dose escalation procedure, the intra-patient dose escalation procedure comprising consecutive administration of: about 0.04 mg/m 2 /day for a 3-5 day treatment period; about 0.12 mg/m 2 /day for a 3-5 day treatment period; about 0.16 mg/m 2 /day for a 3-5 day treatment period; about 0.20 mg/m 2 /day for a 3-5 day treatment period; about 0.24 mg/m 2 /day for a 3-5 day treatment period; about 0.28 mg/m 2 /day for a 3-5 day treatment period; and about 0.32 mg/m 2 /day for a 3-5 day treatment period; wherein each dose is co-administered with an antihistamine; and wherein each successive dose escalation is conditioned upon the absence of dose-limiting toxicity from the previous dose.