Patent ID: 7342106

Claim:
An isolated DNA molecule coding for a single chain Fv (scFv) of a human anti-human MCP-1 antibody that binds to human MCP-1, said DNA molecule comprising a DNA coding for a VH chain of said human anti-human MCP-1 antibody combined with a DNA coding for a VL chain of said human anti-human MCP-1 antibody, wherein complementarity determining regions (CDR1 to CDR3) of said VH chain have the following amino acid sequences: CRD1: Ser Tyr Ala Ile Ser, (SEQ ID NO: 3) CDR2: Gly Phe Asp Pro Glu Asp Gly (SEQ ID NO: 4) Glu Thr Ile Tyr Ala Gln Lys Phe Gln Gly and CDR3: Asp Leu Gly Gly Gly Asp Tyr (SEQ ID NO: 5) Tyr Tyr Gly Met Asp Val and complementarity determining regions (CDR1 to CDR3) of said VL chain have the following amino acid sequences: CDR1: Arg Ser Ser Gln Ser Ile Asn (SEQ ID NO: 8) Thr Tyr Leu His, CDR2: Ala Ala Ser Thr Leu Gln Ser (SEQ ID NO: 9) and CDR3: Gln Gln Ser Phe Thr Thr Pro (SEQ ID NO: 10) Leu Thr.