Patent ID: 7371778

Claim:
A spiro or dispiro 1,2,4-trioxolane, wherein the spiro or dispiro 1,2,4-trioxolane is selected from the group consisting of: cis-Adamantane-2-spiro-3′-8′-[2′-(1′H-tetrazol-5′-yl)ethyl]-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[(1′-piperidinylsulfonyl)methyl]-1′,2′,4′trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[[1′-(2′-amino-2′-methylpropyl)-1′H-tetrazol-5′-yl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[4′-hydroxy-3′-(methoxymethyl)phenyl]-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[4′-[2′-[(aminoiminomethyl)amino]ethoxy]phenyl]-1′,2′,4′-trioxaspiro[4.5]decane hydrochloride, cis-Adamantane-2-spiro-3′-8′-[4′-(2′-aminoethoxy)phenyl]-1′,2′,4′-trioxaspiro[4.5]decane hydrochloride, cis-Adamantane-2-spiro-3′-8′-[4′-(2′-aminomethoxy)phenyl]-1′,2′,4′-trioxaspiro[4.5]decane maleate, cis-Adamantane-2-spiro-3′-8′-[4′-(2′-aminoethoxy)phenyl]-1′,2′,4′-trioxaspiro[4.5]decane citrate, cis-Adamantane-2-spiro-3′-8′-carboxymethyl-1′,2′,4′-trioxaspiro[4.5]decane sodium salt, trans, cis-5-Hydroxyadamantane-2-spiro-3′-8′-carboxymethyl-1′,2′,4′-trioxa-spiro[4.5]decane, trans, cis-5-Hydroxyadamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)-amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane p-tosylate, cis-Adamantane-2-spiro-3′-8′-[4′-hydroxy-3′-(hydroxymethyl)phenyl]-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[3′-[(acetylamino)methyl]-4′-hydroxyphenyl]-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adaniantane-2-spiro-3′-8′-[[(3′-amino-3′-oxopropyl)amnino]methyl]-1′,2′,4′-trioxaspiro[4.5]decane p-tosylate, cis-Adamantane-2-spiro-3′-8′-[3′-(aminomethyl)-4′-hydroxyphenyl]-1′,2′,4′-trioxaspiro[4.5]decane p-tosylate, trans-Adamantane-2-spiro-3′-8′-hydroxymethy-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-formyl-1′,2′,4′-trioxaspiro[4.5]decane, Adamantane-2-spiro-3′-8′,8′-bis(ethoxycrbonyl)-1′,2′,4′-trioxaspiro[4.5]de-cane, Adamantane-2-spiro-3′-8′,8′-dicarboxy-1′,2′,4′-trioxaspiro[4.5]decane, Adamantane-2-spiro-3′-8′,8′-bis(hydroxymethyl)-1′,2′,4′-trioxaspiro[4.5]de-cane, Adamantane-2-spiro-3′-7′,7′-dimethyl-1′,2′,4′-trioxaspiro[4.5]decane, trans-Adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane p-tosylate, cis,cis-5-Hydroxyadamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)-amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane p-tosylate, cis-Adaxnantane-2-spiro-3′-8′-[2′-(methoxycarbonyl)ethyl]-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[[[4′-(2′-hydroxyethyl)-1′-piperazinyl]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, 4-Oxoadamantane-2-spiro-3′-1′,2′,4′-trioxaspiro[4.5]decane, cis-Adamantane-2-spiro-3′-8′-[4′-(3′-aminopropoxy)phenyl]-1′,2′,4′-trioxaspiro[4.5)decane mesylate, and 6-Oxoadamantane-2-spiro-3′-1′,2′,4′-trioxaspiro[4.5]decane.