Patent ID: 6878736

Claim:
A compound of the formula wherein: x is from 0 to 2; R 1 is selected from the group consisting of hydroxy, C 1 to C 9 alkoxy (optionally substituted by halo), C 1 to C 9 cycloalkylalkoxy (wherein the cycloalkyl group is optionally substituted by C 1 to C 4 alkyl or halo, and the alkoxy group is optionally substituted by halo), arylalkoxy (wherein the aryl group is optionally substituted by C 1 to C 4 alkyl, C 1 to C 3 alkoxy or halo, and the alkoxy group is optionally substituted by halo) and C 1 to C 9 alkyl amino (wherein the alkyl group is optionally substituted by halo) R 2 is selected from the group consisting of H, alkyl, aryl, arylalkyl, cycloalkyl and cycloalkylalkyl, wherein alkyl moieties are optionally substituted by halo, and aryl groups are optionally substituted by C 1 to C 4 alkyl, C 1 to C 4 alkoxy and halo, R 3 is absent when —Y—Z—R 2 is attached to N, or R 3 is selected from the group consisting of H, C 1 to C 7 alkyl and benzyl, when —Y—Z—R 2 is not attached to N; Y is C 2 to C 10 alkylene, in which one non-terminal carbon atom may be replaced by O; and Z is wherein R 5 , R 6 and R 7 are independently H, aryl (C 1 to C 3 ) alkyl or cycloalkyl (C 1 to C 3 ) alkyl optionally substituted by halo, and Q is H or methyl, provided that when Z is at least one of R 5 and R 7 is aryl(C 1 to C 3 )alkyl or cycloalkyl(C 1 to C 3 )alkyl, optionally substituted by halo; or a pharmaceutically acceptable salt thereof.