Patent ID: 8524766

Claim:
A compound of Formula 1: any of its stereoisomers or any mixture of its stereoisomers, or an N-oxide thereof, or a pharmaceutically acceptable salt thereof; wherein: X is O; R 1 is selected from the group consisting of SOR 8 , SO 2 R 8 , SO 2 NH 2 and SO 2 NH(CH 3 ); R 2 is selected from the group consisting of H, CN, F, Cl, Br, I and CH 3 ; R 3 is selected from the group consisting of C 1 -C 5 alkyl, allyl, CH 2 CH 2 OCH 3 , CH 2 CH 2 CH 2 F, CH 2 CH 2 CHF 2 , CH 2 CH 2 F, 3,3,3-trifluoropropyl, 4,4,4-trifluorobutyl, CH 2 CH 2 OH, CH 2 CH 2 CH 2 OH, CH 2 CH(OH)CH 3 , CH 2 CH 2 COCH 3 , C 3 -C 6 cycloalkyl, and R 4 is selected from the group consisting of H, C 1 -C 5 alkyl, allyl, CH 2 CH 2 OCH 3 , CH 2 CH 2 CH 2 F, CH 2 CH 2 CHF 2 , CH 2 CH 2 F, 3,3,3-trifluoropropyl, 4,4,4-trifluorobutyl, CH 2 CH 2 OH, CH 2 CH 2 CH 2 OH, CH 2 CH(OH)CH 3 , CH 2 CH 2 COCH 3 , R 5 , R 6 and R 7 are selected from the group consisting of H and CH 3 ; and R 8 is selected from the group consisting of C 1 -C 3 alkyl, CF 3 , CHF 2 , CH 2 F and CN.