Patent ID: 6951724

Claim:
An isolated and purified nucleic acid fragment comprising nucleic acid having complementarity or identity to a mutation in the ataxia-telangiectasia mutated (ATM) gene, the mutation being selected from the group consisting of: (a) 10744A>G; (b) 11482G>A; (c) IVS3-558A>T; (d) 381delA; (e) IVS8-3delGT; (f) 1028delAAAA; (g) 1120C>T; (h) 1930ins16; (i) IVS16+2T>C; (j) IVS21+1G>A; (k) 3085delA; (l) 3381delTGAC; (m) 3602delTT; (n) 4052delT; (o) 4396C>T; (p) 5188C>T; (q) 5546delT; (r) 5791G>CCT; (s) 6047A>G; (t) IVS44-1G>T; (u) 6672delGC/6677delTACG; (v) 6736del11/6749del7; (w) 7159insAGCC; (x) 7671delGTTT; (y) 7705del14; (z) 7979delTGT; (aa) 8177C>T; (ab) 8545C>T; (ac) 8565T>A; (ad) IVS64+1G>T; and (ae) 9010del28.