Patent ID: 8618110

Claim:
A compound of a structural Formula (III): or a salt, solvate, or prodrug thereof; wherein: q is 3; X and Y are O; J, K, L and M are independently CR 25 or N; R 22 is substituted cycloheteroalkyl comprising a substituent selected from the group consisting of aryl, substituted aryl, alkyl, substituted alkyl, arylalkyl, substituted arylalkyl, cycloalkyldiyl, substituted cycloalkydiyl, cycloheteroalkyldiyl, substituted cycloheteroalkyldiyl, and hydroxyl; R 25 is halo, cyano, nitro, hydrogen, OR 26 , S(O) t R 26 , CO 2 R 26 , CONR 26 R 27 or NR 26 R 27 , alkyl, substituted alkyl, heteroalkyl or substituted heteroalkyl, wherein t is 0, 1, or 2; each R 26 and R 27 are independently hydrogen, alkyl, substituted alkyl, cycloheteroalkyl, substituted cycloheteroalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroaryl, substituted heteroaryl, heteroarylalkyl, substituted heteroarylalkyl, heteroalkyl or substituted heteroalkyl; or alternatively, R 26 and R 27 , taken together with the atoms to which they are bonded, form a cycloheteroalkyl or substituted cycloheteroalkyl ring; and with the proviso that Formula (III) does not include 1-[3-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)propyl]-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxide.