Patent ID: 8039474

Claim:
A compound of Formula I: wherein R 1 , R 2 , R 3 , and R 4 independently represent hydrogen, alkyl, alkoxy, halogen, nitro, cyano, trifluoromethyl, or formyl; R 5 represents hydrogen, alkyl, or —CF 3 ; and R 6 represents alkoxy, benzyloxy, 1-phenyl-ethoxy, or —NR 7 R 8 , wherein R 7 and R 8 independently represent hydrogen; alkyl; cyano-alkyl alkenyl; a phenyl or naphthyl group, said groups being optionally mono-substituted by halogen, alkyl, alkoxy, —CF 3 , —OCF 3 , phenyl-alkyl or phenyl-carbonyl; a phenyl or naphthyl group, said groups being di-substituted with a halogen, alkoxy or phenyl; phenyl-alkyl optionally substituted in the alkyl chain by phenyl or optionally substituted in the phenyl ring by methylendioxy; phenyl-alkyl which is di-substituted by halogen or mono-substituted by halogen, —CF 3 , —OCHF 2 , alkyl or alkylsulfanyl; naphthyl-alkyl; phenylcarbonyl; cycloalkyl, wherein cycloalkyl refers to a cyclopentyl or cyclohexyl group, wherein said groups are optionally substituted with an annulated benzene ring; pyridyl-alkyl; thienyl-alkyl; furanyl-alkyl; or imidazolyl-alkyl; or R 7 and R 8 , together with the nitrogen atom to which they are attached, form a heterocyclic 5-, 6-, 7-, or 8-membered ring system with 1 or 2 nitrogen and which ring system is optionally substituted with (i) one or two annulated benzene rings, wherein the benzene rings are unsubstituted or substituted with one or two C1-C4 alkyl, C1-C4 alkoxy, halogen, —CF 3 , or —OCF 3 ; (ii) an unsubstituted phenyl ring; (iii) a mono- or di-substituted phenyl ring, wherein the substituents are halogen, C1-C4 alkyl, C1-C4 alkoxy, —CF 3 , and —OCF 3 ; or (iv) phenyl-alkyl wherein the alkyl chain is substituted by phenyl; or an optically pure enantiomer, a mixture of enantiomers, an optically pure diastereomer, a mixture of diastereomers, a mixture of an enantiomer and a diasteromer, a meso form, or a geometric isomer, thereof; or a pharmaceutically acceptable salt thereof.