Patent ID: 7557232

Claim:
A composition comprising a compound covalently bound to a substrate, said compound having a structure according to Formula (I): wherein n is a member selected from 0 and 1; R 1 , R 2 and R 3 are members independently selected from halogen, OR 10 , NR 10 R 11 , OC(O)R 12 , OS(O) 2 R 12 , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocycloalkyl and a bond to said substrate, wherein each R 10 and each R 11 is a member independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocycloalkyl and a bond to said substrate; and each R 12 is a member independently selected from substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocycloalkyl, with the proviso that at least one of R 1 , R 2 and R 3 is covalently bound to said substrate; L 1 and L 2 are linker groups independently selected from substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl and substituted or unsubstituted heterocycloalkyl, with the proviso that if n is 1, then at least one of L 1 and L 2 comprises a carbon chain having at least 8 carbon atoms in sequence, and if n is 0, then L 2 comprises a carbon chain having at least 8 carbon atoms in sequence, wherein at least two of said carbon atoms in sequence are optionally part of a 5- or 6-membered ring, wherein said ring is a member selected from aryl, heteroaryl and cycloalkyl, and wherein said ring is optionally substituted with a non-polar substituent; R 4 is a member selected from H, acyl, substituted or unsubstituted C 1 -C 4 alkyl, substituted or unsubstituted C 1 -C 4 heteroalkyl, wherein R 4 and a substituent of L 2 , together with the atoms to which they are attached, are optionally joined to form a 3- to 7-membered ring; R 20 is a member selected from H, substituted alkyl, substituted heteroalkyl and substituted heterocycloalkyl, provided that if R 20 is not H, at least one substituent of R 20 is OH; and Y is a member selected from ether, thioether, amide, sulfonamide, carbonate, carbamate, urea and thiourea.