Patent ID: 8178525

Claim:
An oxazolidinone compound with cyclic amidoxime or cyclic amidrazone group, represented by formula 1, an in vivo hydrolysable ester formed on ring A of formula 1, an isomer or a pharmaceutically acceptable salt thereof: wherein, ring A is a residue selected from the group consisting of following structure: R 1 through R 12 , independently of one another, represent hydrogen, a (C 1 -C 7 )alkyl, (C 3 -C 7 )cycloalkyl, (C 6 -C 12 )aryl or (C 4 -C 12 )heteroaryl containing one to four heteroatom(s) selected from the group consisting of O, S and N, or R 3 and R 4 form a ring by connecting with (C 3 -C 5 )alkylene, carbon atom of the alkylene can be substituted with an oxo, alkyl, cycloalkyl, aryl or heteroaryl of the R 1 through R 12 may be substituted with any one selected from the group consisting of (C 1 -C 7 )alkyl, halo(C 1 -C 7 )alkyl, (C 1 -C 7 )alkoxy and halogen; and R 13 is H, (C 1 -C 7 )alkyl, (C 3 -C 7 )cycloalkyl, formyl, (C 1 -C 7 )alkylcarbonyl, (C 1 -C 7 )alkoxycarbonyl or (C 6 -C 12 )aryl.