Patent ID: 7989624

Claim:
A compound of formula I: wherein: B is a selected from the group consisting of: C 3-10 cycloalkyl, phenyl, indanyl, indolinyl, indolyl, isoquinolinyl, tetrahydroisoquinolinyl and tetrahydroquinolinyl, where B is linked to A 1 via a carbon atom in B, and where B is unsubstituted or substituted with 1-5 substituents, each substituent independently selected from C 1-6 alkyl, halo, acetyl and oxo; R 9 is selected from: hydrogen, —C 5-6 cycloalkyl, benzyl, phenyl, and —C 1-6 alkyl which is unsubstituted or substituted with 1-6 fluoro, R 10 is selected from: hydrogen, —C 5-6 cycloalkyl, benzyl, phenyl, —COR 9 , —SO 2 R 12 , and —C 1-6 alkyl which is unsubstituted or substituted with 1-6 fluoro, R 12 is selected from: —C 5-6 cycloalkyl, benzyl, phenyl and —C 1-6 alkyl which is unsubstituted or substituted with 1-6 fluoro, A 1 and A 2 are each independently selected from: (1) a bond, (2) —CR 13 R 14 —, wherein R 13 and R 14 are independently selected from: hydrogen, hydroxyl and C 1-6 alkyl which is unsubstituted or substituted with 1-6 fluoro, (3) —NR 10 —, (4) —CR 13 R 14 —NR 10 —, (5) —CR 13 R 14 —CH 2 —, (6) —CH 2 —CR 13 R 14 —, (7) —O—CR 13 R 14 —, (8) —CR 13 R 14 —O—, and (9) —C≡C—, (10) —C(R 13 )═C(R 14 )—, and (11) —C(═O)—, or wherein one of A 1 and A 2 is absent; J is ═C(R 6a )—; K is ═C(R 6b )—; X is —CO— or —SO 2 —; R 4 is selected from: hydrogen, C 5-6 cycloalkyl, benzyl, phenyl and C 1-6 alkyl which is unsubstituted or substituted with 1-6 fluoro; R 5a , R 5b and R 5c are each independently selected from: hydrogen, C 1-6 alkyl, —O—C 1-6 alkyl, —OCF 3 , trifluoromethyl, halo, hydroxy and —CN; R 6a and R 6b and the atom(s) to which they are attached are joined together to form a ring selected from phenyl, pyridyl and pyrimidinyl, where said ring is unsubstituted; m is 1; n is 1; and pharmaceutically acceptable salts thereof and individual enantiomers and diastereomers thereof.