Patent ID: 8202988

Claim:
A method for preparing brown algae-derived fucoidan compositions, the method comprising: a) extracting fucoidan from brown algae including: washing brown algae to remove salts and foreign materials, followed by drying such that brown algae have a moisture content of 5 to 10%; crushing the brown algae, followed by roasting at 100 to 130° C. for 10 to 30 min together with stirring to provide roasted brown algae; adding a 5- to 15-fold weight of water to the roasted brown algae and heat-extracting the resulting mixture at 100 to 120° C. for 3 to 6 hours to separate the supernatant comprising fucoidan from the solid filtrate; and heating the supernatant comprising fucoidan to obtain a 7-8 brix fucoidan solution; and b) subjecting the 7-8 brix fucoidan solution to low-molecularization to a point where at least 70% of fucoidan molecules have a molecular weight of 100,000 or less and at least 50% of fucoidan molecules have a molecular weight of 10,000 or less; including: fermenting 1 L of the 7-8 brix fucoidan solution in 0.1 to 0.2 g on a dry weight basis of a bacterial culture containing Vibrio halioticoli , Accession No. KCTC 10998BP, and a glycosyltransferase thereof for 20 min to 4 hours; and heating the resulting solution at 90 to 130° C. for 20 min to 2 hours to sterilize and inactivate the Vibrio halioticoli and the glycosyltransferase.