Patent ID: 7741361

Claim:
A compound of Formula (I) wherein: R 1 is hydrogen or C 1 -C 3 alkyl, each optionally independently substituted with one to three substituent groups selected from hydroxy, halogen, or oxo; R 2 is aryl independently substituted with one to five substituent groups, wherein each substituent group of R 2 is independently C 1 -C 5 alkyl, C 2 -C 3 alkenyl, C 2 -C 3 alkynyl, C 1 -C 5 alkoxy, hydroxy, nitro, trifluoromethyl, trifluoromethoxy, halogen, cyano, acylamino, C 1 -C 5 alkoxycarbonylamino, C 1 -C 5 alkylsulfonylamino, C 1 -C 5 alkylthio, amino wherein the nitrogen atom is optionally independently mono- or di-substituted by C 1 -C 5 alkyl, or ureido wherein either nitrogen atom is optionally independently substituted with C 1 -C 5 alkyl, wherein each substituent group of R 2 is optionally independently substituted with C 1 -C 3 alkyl, halogen, hydroxyl, or amino; R 3 is C 1 -C 8 alkyl independently substituted with one to five substituent groups, wherein each substituent group of R 3 is independently C 3 -C 6 cycloalkyl, aryl, halogen, trifluoromethyl, trifluoromethoxy, or trifluoromethylthio and wherein at least one substituent is a halogen; R 4 is a hydrogen or C 1 -C 5 alkyl, each optionally independently substituted with one to three substituent groups, wherein each substituent group of R 4 is independently selected from halogen, hydroxy, oxo, cyano, amino, or trifluoromethyl; R 5 and R 6 are each independently hydrogen, C 1 -C 5 alkyl, or phenyl, or R 5 and R 6 together with the carbon atom they are commonly attached to form a C 3 -C 8 spiro cycloalkyl ring, each optionally independently substituted with one to three substituent groups, wherein each substituent group of R 5 and R 6 is independently selected from halogen, hydroxy, oxo, cyano, amino, or trifluoromethyl; and R 7 is a heteroaryl group optionally independently substituted with one to three substituent groups, wherein each substituent group of R 7 is independently C 1 -C 3 alkyl, C 2 -C 5 alkenyl, C 2 -C 5 alkynyl, heterocyclyl, aryl, heteroaryl, C 1 -C 5 alkoxy, aminocarbonyl, C 1 -C 3 alkylaminocarbonyl, C 1 -C 3 dialkylaminocarbonyl, halogen, hydroxy, carboxy, cyano, trifluoromethyl, trifluoromethoxy, trifluoromethylthio, nitro, amino wherein the nitrogen atom is optionally independently mono- or di-substituted by C 1 -C 5 alkyl, or C 1 -C 5 alkylthio wherein the sulfur atom is optionally oxidized to a sulfoxide or sulfone, wherein each substituent group of R 7 is optionally independently substituted with one to three substituent groups selected from C 1 -C 3 alkyl, C 1 -C 3 alkoxy, aryl, acyl, acylamino, halogen, hydroxy, oxo, cyano, trifluoromethyl, or amino wherein the nitrogen atom is optionally independently mono- or di-substituted by C 1 -C 5 alkyl, or a tautomer, ester or amide prodrug, or pharmaceutically acceptable salt thereof.