Patent ID: 7645578

Claim:
A method of sample analysis comprising: a) obtaining a set of oligodeoxynucleotides, the set of oligodeoxynucleotides comprising member oligodeoxynucleotides, each member oligodeoxynucleotide directed to a redundant RNA cleavage site, wherein said redundant RNA cleavage site occurs in at least two different positions in the RNA molecules in said sample; b) contacting the sample of RNA with a solution comprising the set of oligodeoxynucleotides under stringent assay conditions to provide DNA/RNA duplexes, c) contacting the DNA/RNA duplexes with an enzyme having a DNA:RNA nuclease activity to provide a digested RNA sample; d) labeling the digested RNA with an observable label to provide labeled RNA; e) contacting the labeled RNA with an array under conditions that provide for specific binding of the labeled RNA to the array; and f) interrogating the array to provide data on binding of the labeled RNA to the array.