Patent ID: 8183249

Claim:
A method for inhibiting the Akt/PKB pathway in a cancer cell in which said pathway is present, wherein said cell constitutively expresses an Akt protein or said cell expresses elevated levels of an Akt protein, said method comprising contacting the cell with an effective amount of a compound according to formula (I): wherein X is N; Y is O, NH, or S; R 1 is, independently, —H, —OH, —NH 2 , —NO 2 , halogen, alkyl optionally substituted with —OH, or alkoxy optionally substituted with —OH; R 2 is —C(O)NH 2 or alkoxy optionally substituted with —OH, halogen, alkyl, or alkoxy; R 3 is —OH, —NH 2 , —C(O)NH 2 , or alkoxy optionally substituted with —OH, halogen, alkyl, or alkoxy; or a pharmaceutically acceptable salt thereof; or a composition comprising said compound.