Patent ID: 7709606

Claim:
An interacting polypeptide comprising the following elements: (a) a heptapeptide motif with the sequence N X 1 WX 3 X 4 X 5 X 6 X 7 C in which X 1 , X 3 , X 4 , X 5 , X 6 and X 7 are amino acids independently selected from natural or modified amino acids, in which X 4 and/or X 5 is a cysteine and in which W is tryptophan; (b) a transduction domain; and (c) a stabilization domain which is a fragment of ubiquitin or SUMO-1, the amino acid sequence of which fragment comprises SEQ ID NO.:1 or SEQ ID NO.:15; characterized in that it is a chimeric polypeptide, in that the amino acid X 7 is 5 to 35 amino acids from the C-terminal end of said polypeptide, in that domain (b) is located C-terminally with respect to motif (a), and in that the stabilization domain (c) is located N-terminally with respect to the heptapeptide motif of said polypeptide.