Patent ID: 7585880

Claim:
A compound represented by the formula (I) wherein X is S or O, R 1 and R 2 are the same or different and each is a hydrogen atom, an optionally substituted C 6-14 aryl group, an optionally substituted heterocyclic group or an optionally substituted C 1-6 alkyl group, or R 1 and R 2 are bonded to each other to form a ring together with the carbon atom they are bonded to, E is —W 1 —N(R 5 )—W 2 —, —W 1 —CH(R 6 )—O—W 2 —, —W 1 —O—CH(R 6 )—W 2 —, —W 1 —S(O)n-W 2 — or —W 1 —CH(R 6 )—W 2 — (W 1 and W 2 are the same or different and each is a bond or an optionally substituted C 1-3 alkylene group, R 5 and R 6 are each an optionally substituted heterocyclic group or an optionally substituted hydrocarbon group, and n is 1 or 2, provided that when X is S, then R 5 and R 6 are not C 1-6 alkyl groups), ring S 1 is a benzene ring or pyridine ring each optionally further having substituent(s) selected from an optionally substituted C 1-6 alkyl group, an optionally substituted C 1-6 alkoxy group and a halogen atom, R 3 and R 4 are the same or different and each is a hydrogen atom, a halogen atom, an optionally substituted C 1-6 alkyl group or an optionally substituted C 1-6 alkoxy group, R 9 and R 10 are the same or different and each is a hydrogen atom, a halogen atom or a C 1-6 alkoxy group, and R is an optionally substituted hydroxy group or an optionally substituted amino group, or a prodrug or a salt thereof.