Patent ID: 7101868

Claim:
Compound of Formula IV wherein R 2 is selected from unsubstituted or substituted phenyl, and 9-10 membered bicyclic and 11-14 membered tricyclic unsaturated or partially unsaturated heterocyclyl, wherein substituted R 2 is optionally substituted with one or more substituents selected from halo, C 1-6 -alkyl, optionally substituted C 3-6 -cycloalkyl, optionally substituted phenyl, optionally substituted phenyl-C 1- C 4 -alkylenyl, C 1-2 -haloalkoxy, optionally substituted phenyloxy, optionally substituted 4-6 membered heterocyclyl-C 1- C 6 -alkyl, optionally substituted 4-6 membered heterocyclyl-C 2- C 4 -alkenyl, optionally substituted 4-6 membered heterocyclyl, optionally substituted 4-6 membered heterocyclyloxy, optionally substituted 4-6 membered heterocyclyl-C 1-4 -alkoxy, optionally substituted 4-6 membered heterocyclylsulfonyl, optionally substituted 4-6 membered heterocyclylamino, optionally substituted 4-6 membered heterocyclylcarbonyl, optionally substituted 4-6 membered heterocyclyl-C 1-4 -alkylcarbonyl, optionally substituted 4-6 membered heterocyclylcarbonyl-C 1-4 -alkyl, optionally substituted 4-6 membered heterocyclyl-C 1-4 -alkylcarbonylamino, optionally substituted 4-6 membered heterocyclyl-oxycarbonylamino, C 1-2 -haloalkyl, C 1-4 -aminoalkyl, nitro, amino, C 1-3 -alkylsulfonylamino, hydroxy, cyano, aminosulfonyl, C 1-2 -alkylsulfonyl, halosulfonyl, C 1-4 -alkylcarbonyl, amino-C 1-4 -alkylcarbonyl, C 1-3 -alkylamino-C 1-4 -alkylcarbonyl, C 1-3 -alkylamino-C 1-4 -alkylcarbonylamino, C 1-4 -alkoxycarbonyl-C 1-4 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkoxy, C 1-3 -alkylamino-C 1-3 -alkoxy-C 1-3 -alkoxy, C 1-4 -alkoxycarbonyl, C 1-4 -alkoxycarbonylamino-C 1-4 -alkyl, C 1-3 -alkylsulfonylamino-C 1-3 -alkoxy, C 1-4 -hydroxyalkyl, and C 1-4 -alkoxy; wherein R e and R f are independently selected from H and C 1-2 -haloalkyl; wherein R g is selected from H, C 1-3 -alkyl, optionally substituted phenyl-C 1-3 -alkyl, 4-6 membered heterocyclyl, and optionally substituted 4-6 membered heterocyclyl-C 1- C 3 -alkyl, C 1-3 -alkoxy-C 1-2 -alkyl and C 1-3 -alkoxy-C 1-3 -alkoxy-C 1-3 -alkyl; and wherein R 8 is one or more substituents independently selected from halo, amino, nitro, hydroxy, C 1-6 -alkyl, C 1-6 -haloalkyl, C 1-6 -alkoxy, C 1-6 -haloalkoxy, C 1-6 -aminoalkyl, C 1-6 -hydroxyalkyl, optionally substituted phenyl, optionally substituted heterocyclyl, optionally substituted heterocyclyl-C 1-6 -alkoxy, aminosulfonyl, C 3-6 -cycloalkyl, C 1-6 -alkylamino, C 1-6 -alkylamino-C 1-6 -alkyl, optionally substituted heterocyclyl-C 1-6 -alkylamino, optionally substituted heterocyclyl-C 1-6 -alkyl, C 1-6 -alkylamino-C 2-4 -alkynyl, C 1-6 -alkylamino-C 1-6 -alkoxy, C 1-6 -alkylamino-C 1-6 -alkoxy-C 1-6 -alkoxy, and optionally substituted heterocyclyl-C 2-4 -alkynyl; and a pharmaceutically acceptable salt thereof; provided R 2 is not 3-trifluoromethylphenyl when R 8 is 4-hydroxy or 3-hydroxy.