Patent ID: 7129246

Claim:
A compound of formula wherein m represents 1, 2 or 3; each R 1 independently represents a hydrogen or halogen atom; A represents C(O)NH or NHC(O); Ar represents a group one of R 2 and R 3 represents halogen, nitro, amino, hydroxyl, or a group selected from (i) C 1 –C 6 alkyl optionally substituted by at least one halogen atom, (ii) C 3 –C 8 cycloalkyl, (iii) C 1 –C 6 alkoxy optionally substituted by at least one halogen atom, and (iv) C 3 –C 8 cycloalkyloxy, and the other of R 2 and R 3 represents a hydrogen or halogen atom; R 4 represents a group X represents an oxygen or sulphur atom or a group >N—R 8 ; n is 0 or 1; R 5 represents a C 1 –C 5 alkyl group which may be optionally substituted by at least one substituent selected from hydroxyl, halogen and C 1 –C 6 alkoxy; R 6 and R 7 each independently represent a hydrogen atom, C 1 –C 6 alkyl (optionally substituted by at least one substituent selected from hydroxyl, halogen, C 1 –C 6 alkoxy, and (di)-C 1 –C 4 alkylamino (itself optionally substituted by at least one hydroxyl group)), or C 3 –C 8 cycloalkyl (optionally substituted by at least one substituent selected from hydroxyl, halogen and C 1 –C 6 alkoxy); and R 8 represents a hydrogen atom or a C 1 –C 5 alkyl group which may be optionally substituted by at least one substituent selected from hydroxyl, halogen and C 1 –C 6 alkoxy; with the provisos that: (a) when n is 0, then A is NHC(O), and (b) when n is 1, X represents oxygen and A is C(O)NH, then R 6 and R 7 do not both simultaneously represent a hydrogen atom or do not both simultaneously represent an unsubstituted C 1 –C 6 alkyl, or when one of R 6 and R 7 represents a hydrogen atom, then the other of R 6 and R 7 does not represent an unsubstituted C 1 –C 6 alkyl; and (c) when n is 1, X is oxygen, sulphur or NH and A is NHC(O), then R 6 and R 7 do not both simultaneously represent a hydrogen atom or do not both simultaneously represent an unsubstituted C 1 –C 6 alkyl, or when one of R 6 and R 7 represents a hydrogen atom, then the other of R 6 and R 7 does not represent an unsubstituted C 1 –C 6 alkyl or —CH 2 CH 2 OH; or a pharmaceutically acceptable salt or solvate thereof.