Patent ID: RE39128

Claim:
A compound of general formula (IA) or (IB): in which: each of n and m is independently 0, 1 or 2; and X is selected from —O—, —S—, —S(O)—, —SO 2 —, —CO.O—, —NH—, —CONH—, —NHCONH— and a bond; or n is 1 or 2 and m is 2 and X is —S—; and R 1 is vinyl or ethyl; R 2 is optionally substituted quinuclidinyl, azabicyclo[2.2.1]heptyl, azabicyclo[4,3,0]nonyl, azabicyclo[3.2.1]octyl, azabicyclo[3,3,0]octyl, azabicyclo[2.2.2]octyl, azabicyclo[3.2.1]octenyl, azabicyclo[3.3.1]nonyl or azabicyclo[4.4.0]decyl; wherein R 2 is attached through a ring carbon atom; R 3 is H or OH; or the moiety R 2 (CH 2 ) m X(CH 2 ) n CH 2 COO at position 14 of (IA) or (IB) is replaced by R a R b C=CHCOO in which one of R a and R b is hydrogen and the other is R 2 or R a and R b together form R 2 ; or a pharmaceutically acceptable salt thereof.