Patent ID: 7888343

Claim:
A compound of the formula I, wherein: R1, R2 and R3 are independently selected from the group consisting of H, (C 1 -C 10 )-alkyl, (C 3 -C 10 )-cycloalkyl, (C 2 -C 10 )-alkenyl, (C 2 -C 10 )-alkynyl, (C 6 -C 10 )-aryl, and heterocycle, where the alkyl, cycloalkyl, alkenyl, alkynyl, aryl and heterocycle groups may be substituted one or more times by F, Cl, Br, I, CN, NO 2 , SH, OH, (C 1 -C 6 )-alkyl, —CF 3 , —OCF 3 , —SCF 3 , (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, OR7, OP(O)(OR7) 2 , NR7R8, NR7CONR7R8, COR7, OCOR7, OCOOR7, COOR7, CONR7R8, OCONR7R8, (C 1 -C 6 )-alkylene-OR7, (C 1 -C 6 )-alkylene-NR7R8, (C 1 -C 6 )-alkylene-NR7SO 2 R7, (C 1 -C 6 )-alkylene-SR7, alkylene-S(O)R7, alkylene-S(O) 2 R7, alkylene-S(O) 2 NR7R8, (C 1 -C 6 )-alkylene-COR7, (C 1 -C 6 )-alkylene-COOR7, (C 1 -C 6 )-alkylene-CONR7R8, SR7, SOR7, SO 2 R7, SO 2 NR7R8, NR7SO 2 R7, (C 1 -C 6 )-alkylene-(C 3 -C 10 )-cycloalkyl, (C 1 -C 6 )-alkylene-(C 6 -C 10 )-aryl, (C 1 -C 6 )-alkylene-heterocycle, (C 3 -C 10 )-cycloalkyl, (C 6 -C 10 )-aryl and heterocycle; R7 and R8 are independently selected from the group consisting of H, (C 1 -C 6 )-alkyl, (C 3 -C 10 )-cycloalkyl, (C 6 -C 10 -aryl, heterocycle, (C 1 -C 6 )-alkylene-CONR9R10, (C 1 -C 6 )-alkylene-COOR9, (C 1 -C 6 )-alkylene-COR9, (C 1 -C 6 )-alkylene-OR9, (C 1 -C 6 )-alkylene-NR9R10, (C 1 -C 6 )-alkylene-SR9, (C 1 -C 6 )-alkylene-S(O)R9, (C 1 -C 6 )-alkylene-S(O) 2 R9, (C 1 -C 4 )-alkylene-(C 6 -C 10 )-aryl and (C 1 -C 4 )-alkylene-heterocycle; R9 and R10 are independently selected from the group consisting of H, (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylene-(C 6 -C 10 )-aryl, and (C 1 -C 6 )-alkylene-heterocycle; R12 is selected from the group consisting of F, Cl, Br, I, (C 1 -C 6 )-alkyl, (C 3 -C 8 )-cycloalkyl, NH 2 , NH(C 1 -C 6 )-alkyl, NH(C 3 -C 7 )-cycloalkyl, N((C 1 -C 6 )-alkyl) 2 and O—(C 1 -C 6 )-alkyl, where the alkyl groups may be substituted one or more times by F, Cl, Br, I; n is 0 and wherein the portion of formula I represented by structure A is selected from the group consisting of structures A1 to A6 where optionally the carbon atoms in structures A1 to A6 may be substituted one to four times by a moiety selected from the group consisting of F, Cl, Br, I, (C 1 -C 6 )-alkyl, (C 3 -C 8 )-cycloalkyl, NH 2 , NH(C 1 -C 6 )-alkyl, NH(C 3 -C 7 )-cycloalkyl, N((C 1 -C 6 )-alkyl) 2 and O—(C 1 -C 6 )-alkyl, and wherein optionally the alkyl groups may be substituted one or more times by F, Cl, Br, I; R11 is selected from the group consisting of hydrogen, (C 1 -C 6 )-alkyl, (C 3 -C 8 )-cycloalkyl, (C 1 -C 4 )-alkylene-aryl and (C 1 -C 4 )-alkylene-heterocycle; and or a physiologically tolerated salt thereof.