Patent ID: 7135575

Claim:
A compound including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, said compound having the Formula: wherein Y is C, N; W is C or N, provided that W is N, when Y is C, and W is C when Y is N; U is CH; V is C-E; X is O, S, SO, SO 2 , or NR 7 ; Z is alkylene having from 1 to 4 carbons, or alkenylene or alkynylene each having from 2 to 4 carbons, wherein said alkylene, alkenylene, or alkynylene may be substituted or unsubstituted; R 7 is H or substituted or unsubstituted methyl; Ar 1 is aryl which may be substituted or unsubstituted; A is H, alkyl, allyl, alkenyl, or alkynyl, wherein said alkyl, allyl, alkenyl, and alkynyl, may be substituted or unsubstituted; R 2 and R 3 are independently H, OH, an amine protecting group, alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n -cycloalkyl, or Z n -Ar 1 , wherein said alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n -cycloalkyl, or Z n -Ar 1 may be substituted or unsubstituted, B is H, NH 2 , or substituted or unsubstituted methyl; E is Z n -(C═O)R 4 ; R 4 is NR 2 R 3 ; and n is 0 or 1, provided that when B is H and A is CH═CH—R 8 where R 8 is a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, then X is not O, S, SO NH, or N(C 1 -alkyl).