Patent ID: 6900015

Claim:
A method for monitoring the status of a transplanted organ in a host, the method comprising: a) providing a post-transplantation sample from the host; b) determining the level of gene expression in the post-transplantation sample of at least one gene, wherein the at least one gene is heme oxygenase 1 (HO1) or A20; c) comparing the level of gene expression of the at least one gene in the post-transplantation sample to a baseline level of gene expression of the at least one gene or to a baseline level of gene expression of a constitutively expressed gene; and d) determining whether the at least one gene is upregulated relative to the baseline level of gene expression of the at least one gene or to the baseline level of gene expression of a constituitively expressed gene, wherein upregulation of the at least one gene indicates that the host is likely to experience transplant rejection; thereby monitoring the status of the transplanted organ.