Patent ID: 7842453

Claim:
A method of identifying an agent that modulates the function of ChemerinR polypeptide, wherein said ChemerinR polypeptide sequence is SEQ ID NO: 2, or 4, or 6, said method comprising: contacting said ChemerinR polypeptide with a Chemerin polypeptide comprising an amino acid sequence selected from the group consisting of YFPGQFAFS (SEQ ID NO: 61) and FLPGQFAFS (SEQ ID NO: 47) in the presence or absence of a candidate modulator; and measuring a signaling activity of said ChemerinR polypeptide, wherein a change in the activity in the presence of said candidate modulator relative to the activity in the absence of said candidate modulator identifies said candidate modulator as an agent that modulates the function of said ChemerinR polypeptide.