Patent ID: 7524955

Claim:
A process for the preparation of a compound of Formula (1): which comprises a) reacting a compound of formula R 1 —CO—CH 2 -E with a compound of formula R 2 —CHX 1 X 2 in the presence of a compound of formula R 3 R 4 N—C(═NH)NH 2 and a catalyst, thereby forming a dihydropyrimidine; and b) oxidising the dihydropyrimidine produced in a) to form the compound of Formula (1) wherein R 1 is H or an alkyl group; R 2 is H, an alkyl, or aryl group; R 3 and R 4 are each independently H, alkyl, or aryl; or R 3 and R 4 are linked to form, together with the nitrogen to which they are attached, a 5 to 7 membered heterocyclic ring; E is H, an unsubstituted alkyl group, an aryl group, or an electron withdrawing group; and X 1 and X 2 are each independently leaving groups; or X 1 and X 2 together are ═O.