Patent ID: 7041688

Claim:
A compound of formula I: wherein X represents Ar, L-N(R 1 ) 2 , L-CON(R 1 ) 2 , L-CO 2 R 1 or L-CN; L represents a hydrocarbon chain of 1–7 carbon atoms which, when the chain consists of 2 or more carbon atoms, is optionally interrupted by an oxygen atom; R 1 represents H or R 2 ; or two R 1 groups attached to a single nitrogen atom may complete a heterocyclic ring of 3–7 members bearing 0–3 substituents selected from halogen, oxo, NO 2 , CN, CF 3 , R 2 , C 2-6 acyl, C 2-6 alkenyl, OH, OR 2 , CO 2 H, CO 2 R 2 , Ar, ArCH 2 O, and ArO; R 2 represents C 1-6 alkyl which is optionally substituted with halogen, Ar, NO 2 , CN, CF 3 , OH or C 1-4 alkoxy; R 14 represents H or C 1-6 alkyl, C 3-7 cycloalkyl, C 3-6 cycloalkylC 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, phenyl or benzyl, any of which optionally bear up to 3 halogen substituents or one substituent selected from CN, NO 2 , OH, C 1-4 alkoxy, CO 2 H, C 1-4 alkoxycarbonyl, C 2-6 acyl, C 2-6 acyloxy, amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino, C 2-6 acylamino, carbamoyl, C 1-4 alkylcarbamoyl and di(C 1-4 alkyl)carbamoyl; and Ar represents phenyl or heteroaryl either of which optionally bears up to 3 substituents independently selected from halogen, CF 3 , NO 2 , CN, OCF 3 , C 1-6 alkyl and C 1-6 alkoxy; or a pharmaceutically acceptable salt thereof.