Patent ID: 7833735

Claim:
A method for monitoring the progression and pathological phenomena of leukemia or lymphomas in a subject, said method comprising: A. Preparing a test sample which comprises lymphocytes and mononuclear phagocytes; B. Blocking CD4 or chemokine receptors on the plasma membranes of lymphocytes and mononuclear phagocytes in said test sample by contacting; C. Contacting said plasma membranes of said lymphocytes and mononuclear phagocytes with an immunoreagent specific for interaction with HLE on said plasma membranes, so as to form an immunocomplex; D. Monitoring the test sample for the characteristic physical change in the lymphocytes or phagocytes resulting from the immunocomplex; and E. Relating the immunocomplex to HLE density, where a change in HLE density corresponds to the progression and pathological phenomenona of leukemia or lymphomas in a subject.