Patent ID: 8580783

Claim:
A compound of the formula (I): wherein: m is 0, 1 or 2; X is phenyl, naphtyl, pyridine, furan or thiophene; any R1, if present, is independently halogen, trifluoromethyl, cyano, nitro, CONHRa, ORa, NRbRc, NHCORa, NHSO 2 Ra, SO 2 Rd, COORe or an optionally substituted group selected from linear or branched C 1 -C 7 alkyl, C 2 -C 7 alkenyl, C 2 -C 7 alkynyl, C 3 -C 8 cycloalkyl, C 4 -C 8 cycloalkenyl and C 4 -C 8 heterocyclyl, wherein Ra is hydrogen, trifluoromethyl or an optionally substituted group selected from linear or branched C 1 -C 7 alkyl, C 2 -C 7 alkenyl, C 2 -C 7 alkynyl, C 3 -C 8 cycloalkyl, C 4 -C 8 cycloalkenyl, C 4 -C 8 heterocyclyl, aryl and heteroaryl; Rb and Rc, the same or different, are hydrogen or an optionally substituted group selected from linear or branched C 1 -C 7 alkyl, C 2 -C 7 alkenyl, C 2 -C 7 alkynyl, C 3 -C 8 cycloalkyl, C 4 -C 8 cycloalkenyl, C 4 -C 8 heterocyclyl, aryl and heteroaryl or Rb and Rc together with the nitrogen atom to which they are bonded form an optionally substituted heterocyclyl group comprising oxygen, sulfur or nitrogen atom, Rd is an optionally substituted linear or branched C 1 -C 7 alky, Re is hydrogen or an optionally substituted linear or branched C 1 -C 7 alky; W is a substituted linear or branched C 1 -C 7 alkyl or an optionally substituted aryl or heteroaryl, optionally fused with C 3 -C 8 cycloalkyl or C 4 -C 8 heterocyclyl; Z is CH 2 , CH(OR2) or CH(NHR3), wherein R2 is hydrogen or an optionally substituted linear or branched C 1 -C 7 alky, R3 is hydrogen or COR4, wherein R4 is O—C 1 -C 7 Alkyl, and pharmaceutically acceptable salts thereof, provided that 5-benzyl-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine is excluded.