Patent ID: 7517993

Claim:
A method for making pioglitazone hydrochloride in Form I, having an X-ray diffraction pattern characterized by major peaks at about 8.7, 12.9, 19.8, 20.1, 20.8, 22.9, 26.2, 27.5, and 28.4±0.2 degrees two theta, and a DSC thermogram characterized by a peak at 195° C. when heated at 10° C. per minute, comprising the steps of: a) dissolving pioglitazone hydrochloride in a solubilizing solvent selected from dimethyl formamide, dimethyl acetamide, acetic acid to form a solution, b) cooling the solution whereby a precipitate forms, and c) collecting pioglitazone hydrochloride Form I.