Patent ID: 8563725

Claim:
A process for preparing a compound having Formula (II), wherein the compound having Formula (II) is substantially metal-free: the process comprising: a) contacting a compound having Formula (I) with a transition metal catalyst to form a reaction product comprising the compound having Formula (II); and b) contacting the reaction product of step (a) with a metal scavenger such that the metal scavenger binds the transition metal catalyst, thereby yielding the substantially metal-free compound having Formula (II), the compound of Formula (I) being: wherein: A is oxygen; R 1 , R 2 , and R 3 are independently chosen from hydrogen, halogen, hydroxy, protected hydroxy, {—}SH, {—}SR 1611 , {—}OR 1611 , and {—}NR 1611 R 1612 , hydrocarbyl, and substituted hydrocarbyl; R 5 , R 7 , R 8 , R 9 , R 10a , R 10b , R 14 , R 15a , R 15b , R 16a , R 16b , and R 17 are independently chosen from hydrogen, halogen, hydroxy, {—}SH, {—}SR 1611 , {—}OR 1611 , and {—}NR 1611 R 1612 , hydrocarbyl, and substituted hydrocarbyl; provided that any of R 10a and R 10b , R 15a and R 15b , and R 16a and R 16b may together form a moiety selected from the group consisting of {═}O, {═}S, and {═}NR 1613 ; and R 1611 , R 1612 , an R 1613 are independently chosen from hydrocarbyl, and substituted hydrocarbyl.