Patent ID: 6975902

Claim:
An agent-containing reservoir for incorporation into an electrotransport delivery system adapted to be placed in agent-transmitting contact with a subject body surface for delivering the agent through the body surface by means of an electrotransport current (i) applied to the reservoir via a reservoir-contacting electrode, the reservoir being permeable to electrically assisted flux of the agent and having: (a) a predetermined volume that holds a quantity of the agent sufficient to achieve therapeutically effective delivery of the agent during the entire intended duration of use, wherein the predetermined volume for a given reservoir thickness is defined by the reservoir average cross-sectional area A RES ; (b) a surface that is placed in contact with the body of the subject during use, the body-contacting surface having an area A BODY that provides at least one of (i) a reservoir/body surface current density I BODY , wherein I BODY =i/A BODY , greater than a minimum current density level above which electrotransport delivery Rate/i is approximately maximal and substantially independent of current density occurring at the body-contacting surface during therapeutic use of the device, and (ii) a drug flux j that is biocompatible; and (c) a surface in contact with the electrode, the electrode-contacting surface having an area A ELECTRODE that provides a reservoir/electrode current density I ELECTRODE , wherein I ELECTRODE =i/A ELECTRODE , that results in at least one of (i) a desired electrochemical reaction along the electrode-contacting surface, and (ii) avoidance of undesired polarization along the electrode-contacting surface.