Patent ID: 8524689

Claim:
A compound having the following structure (I): or a stereoisomer or pharmaceutically acceptable salt thereof, wherein: Q 1 is Q 2 is hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted heterocyclyl, optionally substituted heterocyclylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, —C(═NH)NR 7 R 8 , Q 3 is hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted heterocyclyl, optionally substituted heterocyclylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, —C(═NH)NR 7 R 8 , each R 1 and R 2 is, independently, hydrogen or an amino protecting group; each R 3 is, independently, hydrogen or a hydroxyl protecting group; each R 4 , R 5 , R 7 and R 8 is, independently, hydrogen or C 1 -C 6 alkyl optionally substituted with one or more halogen, hydroxyl or amino; each R 6 is, independently, hydrogen, halogen, hydroxyl, amino or C 1 -C 6 alkyl; or R 4 and R 5 together with the atoms to which they are attached can form a heterocyclic ring having from 4 to 6 ring atoms, or R 5 and one R 6 together with the atoms to which they are attached can form a heterocyclic ring having from 3 to 6 ring atoms, or R 4 and one R 6 together with the atoms to which they are attached can form a carbocyclic ring having from 3 to 6 ring atoms, or R 7 and R 8 together with the atom to which they are attached can form a heterocyclic ring having from 3 to 6 ring atoms; each R 9 is, independently, hydrogen, hydroxyl, amino or C 1 -C 6 alkyl optionally substituted with one or more halogen, hydroxyl or amino; each R 10 is, independently, hydrogen, halogen, hydroxyl, amino or C 1 -C 6 alkyl; or R 9 and one R 10 together with the atoms to which they are attached can form a heterocyclic ring having from 3 to 6 ring atoms; and each n is, independently, an integer from 0 to 4, and wherein (i) at least one of Q 2 and Q 3 are other than hydrogen, and (ii) if Q 1 is —C(═O)CH(OH)CH 2 NH 2 , —C(═O)CH(OH)(CH 2 ) 2 NH 2 , or —C(═O)CH(OH)(CH 2 ) 3 NH 2 , then Q 2 is not methyl or —C(═O)OC(CH 3 ) 3 , and (iii) if Q 1 is —C(═O)CH(OH)CH 2 NH 2 or —C(═O)CH(OH)(CH 2 ) 2 NH 2 , then Q 3 is not —C(═O)OC(CH 3 ) 3 , —C(═O)OCH 2 Ph, —C(═O)CH(OH)CH 2 NH 2 or —C(═O)CH(OH)(CH 2 ) 2 NH 2 .