Patent ID: 7228163

Claim:
A method for monitoring an effect of at least one non-insulin-containing pharmaceutical composition on glucose levels in a subject receiving said pharmaceutical composition, the method comprising: monitoring glucose amount or concentration in the subject by a glucose monitoring method comprising: transdermally extracting a sample comprising glucose from the subject using a sampling system that is in operative contact with a skin or mucosal surface of said subject, wherein the extracting is carried out using an iontophoretic system comprising first and second iontophoretic electrodes; contacting the sample with a sensor element in the presence of glucose oxidase that reacts with glucose to produce hydrogen peroxide; detecting the hydrogen peroxide with the sensor element that reacts electrochemically with the hydrogen peroxide to produce a detectable signal, wherein said detectable signal is specifically related to glucose amount or concentration in the subject; measuring the detectable signal; correlating the signal measurement to an amount or concentration of glucose in the subject; and repeating said glucose monitoring method to obtain a series of glucose amounts or concentrations, in the subject, at selected time intervals; maintaining a record of treatment with the pharmaceutical composition; and comparing said series of glucose amounts or concentrations and said record to evaluate the effect of the pharmaceutical composition on glucose levels in the subject receiving said pharmaceutical composition, wherein the pharmaceutical composition is not used in the subject for the treatment of diabetes and is selected from the group consisting of pentamidine, quinine, saquinavir and indomethacin.