Patent ID: 8053585

Claim:
A photolabile compound comprising: a coumarin family caging group covalently bound to an organic moiety containing a carboxyl group, an amino group, a sulfhydryl group, and/or a hydroxyl group, wherein: the organic moiety is an amino acid selected from the group consisting of: aspartic acid; beta alanine; saclofen; S-sulpho-L-cysteine; γ-N-oxalyl-L-α,γ-diaminobutyric acid; O-phospho-D-serine philanthotoxin 343; (±)-cis-2,3-piperidinedicarboxylic acid; piperidine-4-sulphonic acid; L-trans-pyrrolidine-2,4-dicarboxylic acid; isoguvacine; indole-2-carboxylic acid; (+)-α-methyl-4-carboxyphenylglycine; 6-nitroquinoxaline-2,3-dione; γ-D-glutamylaminoethylphosphonic acid; D-homocysteic acid; L-homocysteinesulphinic acid; (RS)-3-hydroxyphenylglycine; 3-hydroxy-2-quinoxaline-carboxylic acid; 5-7-dichlorokynurenic acid; dihydrokainic acid; domoic acid; L-glutamic acid; (S)-4-carboxyphenylglycine; 6-chlorokynurenic acid; D-cysteic acid; L-cysteine sulphinic acid; (±)-3-carboxyphenylalanine; (R)-5-bromowillardiine; aminomalonic acid; and glycine; the coumarin family caging group is 7-N,N-diethylamino-4-hydroxymethyl coumarin and is covalently bound to the organic moiety through a hydroxyl group on the coumarin compound and through the carboxyl group, amino group, sulfhydryl group, or hydroxyl group on the organic moiety; and the photolabile compound, upon absorbing visible light, releases the organic moiety.