Patent ID: 6967242

Claim:
A compound of formula I: wherein R 1 and R 2 are independently amino or protected amino; X is O, S, NH or CH 2 ; Y is (CH 2 ) n ; n is 1 to 10; R 3 is aryl or heteroaryl; or R 3 is a substituted aryl or a substituted heteroaryl having at least one substituent group selected from the list consisting of OH, SH, Cl, F, Br, I, CN, NH 2 , NO 2 , amidine, guanidine, COOH, C 1-8 alkyl, C 2-8 alkenyl, alkynyl, CF 3 , OCF 3 , saturated or unsaturated carbocycle, saturated or unsaturated heterocycle, aryl, heteroaryl, OR 14 , SR 14 , NHR 14 , N(R 14 ) 2 , C(S)R 14 , C(O)R 14 , C(O)NHR 14 , C(O)OR 14 , OC(O)R 14 , wherein R 14 is hydrogen, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, carbocyclic, heterocyclic, aryl or a heteroaryl group; one of R 4 and R 5 is hydroxyl or protected hydroxyl, and the other is selected from the group consisting of formula II and IV: wherein R 6 and R 7 are independently hydroxyl or protected hydroxyl; R 8 , R 9 , R 10 , and R 11 are independently hydroxyl, protected hydroxyl, amino or protected amino; R 12 and R 13 are independently H or alkyl; and Z is O, S or NH.