Patent ID: RE39043

Claim:
A method for promoting collagen production in a fibroblast of a subject comprising topically administering to said subject a collagen production promoter composition in an amount effective to promote collagen production in a fibroblast, wherein said composition comprises, as active components, (i) 0.0001 to 30.0% by weight, based upon the total weight of the composition, of an extract obtained by extracting a shoot of Fagus crenata with at least one solvent, wherein the advent is selected from the group consisting of water, ethanol, methanol, propanol, butanol, 1,3-butylene glycol and any mixtures thereof, and (ii) vitamin C a compound selected from the group consisting of L-ascorbic acid, L-ascorbate dipalmitate esters, L-ascorbate Monopalmitate esters, sodium L-ascorbate- 2 -sulfate, L-ascorbate phosphate esters, L-ascorbate stearate esters, L-ascorbate- 2 -glycoside or dipotassium DL-α-tocopherol-L-ascorbate phosphate diester or mixtures thereof in an amount effective for synergistic promotion of collagen production.