Patent ID: 7022706

Claim:
A compound having the structure represented by the formula: wherein Cy represents a 5 or 6 member aromatic ring or substituted 5 or 6 member aromatic ring, B′ is ethylenic, or acetylenic, Q is (CH 2 ) m , Q′ is (CH 2 ) p , and Q″ is (CH 2 ) q where m is 1, 2, 3 or 4, p is 0, 1, 2 or 3, and q is 0, 1 or 2, and the values of m, p and q are selected such that the azabicyclic ring shown in the structure contains 7 members, and either p or q is 1; Z represents a non-hydrogen substituent group selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, heterocyclyl, substituted heterocyclyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl, substituted arylalkyl, halo, —NR′R″, —CF 3 , —OH, —CN, —NO 2 , —C 2 R′, —SH, —SCH 3 , —N 3 , —SO 2 CH 3 , —OR′, —SR′, —C(═O)NR′R″, —NR′C(═O)R′, —C(═O)R′, —C(═O)OR′, —(CH 2 ) x OR′, —OC(═O)R′, —(CR′R″) x OCH 2 C 2 R′, —(CR′R″) x C(═O)R′, —O(CR′R″) x C(═O)R′, —C 2 (CR′R″) x OR′, —(CR′R″) x NR′R″, —OC(═O)NR′R″ and —NR′C(═O)OR′, wherein x is an integer from 1 to 6, R′ and R″ are individually hydrogen or C 1 -C 8 alkyl, an aromatic group-containing species or a substituted aromatic group-containing species, where the aromatic group-containing species are selected from the group consisting of pyridinyl, quinolinyl, pyrimidinyl, phenyl, and benzyl, or R′ and R″ can form a cycloalkyl functionality, any of the foregoing groups indicated as being substituted can be suitably substituted with at least one substituent group selected from the group consisting of alkyl, hydroxyl, alkoxy, halo, and amino substituents, j is an integer from 0 to 5, Z′ represent hydrogen or lower alkyl, the dotted lines in the structure signify carbon-carbon single bonds or carbon-carbon double bonds with the proviso that where B′ is alkylenic, only one dotted line represents a carbon-carbon double bond, and when B′ is ethylenic or acetylenic, no dotted line represents a carbon-carbon double bond, and ethylenic is —CE′═CE″-, wherein E′ and E″ are hydrogen or a non-hydrogen substituent as defined above with respect to Z, and acetylenic is —C═C—, wherein the term “substituted” as applied to the terms “substituted alkyl, substituted alkenyl, substituted heterocyclyl, substituted cycloalkyl, substituted aryl, substituted alkylaryl, arylalkyl, and substituted arylalkyl refers to one or more alkyl, hydroxy, alkoxy, halo or amino substituents.