Patent ID: 6855822

Claim:
A compound of the formula I wherein L is selected from —(CH 2 ) a —, and a group of the formula —B—A—B— wherein a is selected from 2-20, B is —(CH 2 ) b —, —(CH 2 ) c —O—(CH 2 ) d —, or and A is selected from a group of the formula wherein R 4 is selected from halogen, lower alkyl, lower alkoxy, NO 2 , and —NRR, D and E are independently selected from O, S, Se, CRR and NR, b is selected from 1-10, c is selected from 1-8, d is selected from 1-8, e is selected from 0-4; f is selected from 0-3, and R is selected from H, lower alkyl, aralkyl and aryl; X is selected from O, or —NH—; R 1 is selected from a C 1 -C 20 alkyl which may be unsubstituted or substituted with one or more substituents selected from CN, halogen, lower alkoxy, thio-lower alkyl, nitro, phosphinos, phosphates, and protected amino; a C 1 -C 20 alkenyl which may be unsubstituted or substituted with one or more substituents selected from CN, halogen, lower alkoxy, thio-lower alkyl, nitro, phosphinos, phosphates, and protected amino; an aromatic group which may be unsubstituted or substituted with one or more substituents selected from halogen, lower alkyl, lower alkoxy, thio-lower alkyl, nitro, phosphinos, phosphates, and protected amino; and an aralkyl which may be unsubstituted or substituted with one or more substituents selected from halogen, lower alkyl, lower alkoxy, thio-lower alkyl, nitro, phosphinos, phosphates, and protected amino; R 2 is selected from halogen, hydroxy, CN, nitro, lower alkyl, lower alkoxy, thio-lower alkyl, lower alkenyl, cycloalkyl, C 2 -C 8 acyl, lower alkyl ester, and lower alkyl amide; R 3 is a group of the formula —(CH 2 ) p —Y q —(CH 2 ) r —Z s —(CH 2 ) t —R 5 wherein Y and Z are independently selected from O, S, —OCH 2 CH 2 O—, p, r and t are independently selected from values from 0 to 10; q and s are independently selected from 0 and 1, provided that when t=0 then s=0, and when r=0 then q=0; and R 5 is selected from OH, CO 2 H, n is selected from 0-4; and m is 0 or 1, with the proviso that the sum of n plus m does not exceed 4.