Patent ID: 8592625

Claim:
A process for resolving S-3-(Aminomethyl)-5-methylhexanoic acid, comprising the following steps: a. Resolving racemic 3-aminomethyl-5-methylhexanoic acid as a raw material in a polar solvent by using benzoyl-L-glutamic acid, or 4-methyl-benzoyl-L-glutamic acid, or benzene sulfonyl-L-glutamic acid, or 4-methyl benzene sulfonyl-L-glutamic acid as a resolution agent, so as to obtain a resolution salt product; b. Hydrolyzing the resolution salt product by adding an acid, separating the resolution agent by extraction, adjusting pH to be neutral, then precipitating the product S-3-(Aminomethyl)-5-methylhexanoic acid by distillation.