Patent ID: 7094780

Claim:
A compound of Formula I or a pharmaceutically acceptable salt thereof wherein: R 1 and R 3 independently are H, C 1 –C 12 alkyl and substituted alkyl, C 2 –C 12 alkenyl and substituted alkenyl, C 2 –C 12 alkynyl and substituted alkynyl, C 3 –C 12 cycloalkyl and substituted cycloalkyl, aryl and substituted aryl, heterocyclic and substituted heterocyclic, or heteroaryl and substituted heteroaryl; R 5 , R 6 , and R 8 independently are H, (O) n C 1 –C 12 alkyl and substituted alkyl, (O) n C 2 –C 12 alkenyl and substituted alkenyl, (O) n C 2 –C 12 alkynyl and substituted alkynyl, wherein n is 0 or 1, halo, NO 2 , CN, NR′R″; R′ and R″ independently are H, C 1 –C 12 alkyl and substituted alkyl, C 2 –C 12 alkenyl and substituted alkenyl, C 2 –C 12 alkynyl and substituted alkynyl, CO—C 1 –C 12 alkyl and substituted alkyl, or R′ and R″ taken together with the nitrogen to which they are attached form a 3- to 7-membered ring containing from 1 to 3 heteroatoms selected from N, O, and S, said ring being unsubstituted or substituted with up to 4 substituent groups; R 1 and R 8 can be taken together with the atoms to which they are attached to form a cyclic ring having from 1 to 3 heteroatoms selected from N, O, and S, and optionally substituted by R′ and R″; R 7 is C 2 –C 12 alkenyl and substituted alkenyl, C 2 –C 12 alkynyl and substituted alkynyl, NO 2 , CN, NR′R″, COOR′, aryl, fused aryl, heterocyclic, fused heterocyclic, bicyclic heterocyclic, or spiro heterocyclic, wherein all ring groups can be substituted; and J and K are C.