Patent ID: 8758726

Claim:
A method of imaging by positron emission tomography (PET) or magnetic resonance imaging (MRI) comprising: a) obtaining an 19 F- or 18 F-labeled targeting molecule comprising a bifunctional chelating agent of the structure wherein R 1 and R 2 are independently selected from the group consisting of and R 3 is selected from the group consisting of: wherein M selected from the group consisting of aluminum, gallium, indium, lutetium and thallium and X is 19 F or 18 F, wherein n=1-9 and wherein R=F, CH 2 F, CHF 2 , CH 3 or OCF 3 ; b) administering the 19 F- or 18 F-labeled targeting molecule to a subject; and c) imaging the distribution of the 19 F-labeled targeting molecule in the subject by MRI or imaging the distribution of the 18 F-labeled targeting molecule in the subject by PET.