Patent ID: 7521555

Claim:
A process for producing a substituted aniline compound represented by the following general formula (6): wherein R 1 , R 2 and R 3 are each independently an alkyl group, an alkoxy group, an alkoxyalkyl group, a haloalkyl group, a carboxyl group, a nitro group, an aryl group, an arylalkyl group, an aryloxy group, a halogen atom or a hydrogen atom; and X and Y are each independently a hydrogen atom, an alkyl group, an alkoxy group, an alkoxyalkyl group, a haloalkyl group, a carboxyl group, or a halogen atom, the process comprising: oxidizing a substituted indole compound represented by the following general formula (3): wherein R 1 , R 2 , R 3 , X and Y have the same definitions as given above, to open the indole ring to produce an acetanilide compound represented by the following general formula (4): wherein R 1 , R 2 , R 3 , X and Y have the same definitions as given above; and Ac is an acetyl group; and reducing and deacetylating the acetanilide compound of general formula (4) to give compound 6; and further comprising: producing the substituted indole compound of general formula (3) by reacting, in the presence of an acid, a (pyrimidine-2-yl)-2-propanone compound represented by the following general formula (1): wherein R 1 , R 2 and R 3 have the same definitions as given above, with a hydrazine compound represented by the following general formula (2): wherein X and Y have the same definitions as given above.