Patent ID: 6864232

Claim:
A method for treating retinopathy, comprising administering to a subject in need thereof an effective amount of an agent comprising a tricyclo compound of formula (I) wherein adjacent pairs of R 1 and R 2 , R 3 and R 4 , and R 5 and R 6 each independently a) consist of two adjacent hydrogen atoms, wherein R 2 is optionally alkyl, or b) form another bond optionally between carbon atoms binding with the members of said pairs; R 7 is hydrogen atom, hydroxy, protected hydroxy, or alkyloxy, or optionally form oxo with R 1 ; R 8 and R 9 are each independently a hydrogen atom or hydroxy; R 10 is hydrogen atom, alkyl, alkyl substituted by one or more hydroxy, alkenyl, alkenyl substituted by one or more hydroxy or alkyl substituted by oxo; X is oxo, (hydrogen atom, hydroxy), (hydrogen atom, hydrogen atom), or a group of the formula —CH 2 O—; Y is oxo, (hydrogen atom, hydroxyl), (hydrogen atom, hydrogen atom), or a group of the formula N—NR 11 R 12 or N—OR 13 ; R 11 and R 12 are each independently a hydrogen atom, alkyl, aryrl or tosyl; R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 22 and R 23 are each independently a hydrogen atom or alkyl; R 24 is a ring that is optionally substituted and optionally contain one or more hetero atom(s); and n is 1 or 2, wherein Y, R 10 and R 23 are optionally, together with the carbon atom they bind with, a saturated or unsaturated 5 or 6-membered heterocyclic group containing nitrogen atom, sulfur atom and/or oxygen atom, the heterocyclic group being optionally substituted by one or more group(s) selected from the group consisting of alkyl, hydroxy, alkyloxy, benzyl, a group of the formula —CH 2 Se(C 6 H 5 ), and alkyl substituted by one or more hydroxyl, or a pharmaceutically acceptable salt thereof.