Patent ID: 8367606

Claim:
A method comprising treating a skin pathology, disorder, or condition associated with aging by topically administering to the skin of an individual who is aging, a cosmetically effective amount of at least one agent capable of restoring an impaired physiological condition of the skin associated with said skin pathology, disorder, or condition, wherein said at least one agent is a PKC isoform modulator capable of modulating at least one of the expression or activity of at least one PKC isoform selected from PKCα, PKCβ, PKCδ, PKCε, PKGη, PKCξ, PKCγ, PKCθ, PKCλ, or PKCτ, wherein said at least one agent is a PKC isoform inhibitor, which may be a PKC isoform pseudosubstrate inhibitor, a peptide binding to the PKC isoform substrate region, a peptide binding to the ATP-binding site of a PKC isoform, or Copolymer-1.