Patent ID: 7304077

Claim:
A compound of formula (I): wherein R 1 is phenyl optionally substituted by cyano, S(O) 2 (C 1-6 alkyl), S(O) 2 (C 1-6 haloalkyl), halogen, C 1-6 alkyl, C 1-6 haloalkyl or C 1-6 alkoxy; n is 1, 2, 3 or 4; m is 0; q is 0; wherein R 2 and R 3 are, independently, hydrogen or C 1-6 alkyl, and R 4 is hydrogen, then R 5 is phenyl substituted at least once with a substituent selected from the group consisting of: C 1-6 alkyl substituted with at least one of NH 2 , CO 2 (C 1-6 alkyl), S(O) 2 (C 1-6 alkyl), NHS(O) 2 (C 1-6 alkyl) and S(O) 2 NR 13 R 14 , S(O) 2 (C 1-6 alkyl), S(O) 2 (C 1-6 hydroxyalkyl), S(O) 2 NH(C 1-6 alkyl), NHC(O)(C 1-6 alkyl), NHS(O) 2 (C 1-6 alkyl), C 1-6 alkoxy substituted with at least one of C 1-6 alkoxy, hydroxy, CO 2 (C 1-6 alkyl), NHC(O)O(C 1-6 alkyl) and NH 2 , C 2-6 alkenyl, pyrrolyl and Δ 3 -pyrrolinyl; and optionally further substituted with a substituent selected from the group consisting of: halogen, cyano, nitro, hydroxy, C 1-6 alkyl, C 3-6 cycloalkyl, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, C 1-6 haloalkyl, C 1-6 haloalkoxy, NR 6 R 7 , C 3-6 cycloalkylamino, C 1-6 alkylthio, C 1-6 alkylthio(C 1-6 alkyl), C 1-6 alkylcarbonylamino, C(O)NR 8 R 9 , sulphonamido (S(O) 2 NH 2 ), (di)C 1-6 alkylsulphonamido, phenyl, phenylamino, nitrophenyl, pyridyl, pyridylthio, benzodioxanyl, thienyl, furanyl, and C(O)R 10 -substituted C 1-6 alkyl or C 1-6 alkoxy groups; and when R 2 and R 3 are, independently, hydrogen or C 1-6 alkyl, and R 4 is C 1-4 alkyl or C 3-6 cycloalkyl(C 1-4 alkyl), then R 5 is a phenyl optionally substituted by halogen, cyano, nitro, hydroxy, C 1-6 alkyl optionally substituted with one or more of halogen, C 1-6 alkylthio, NH 2 , C(O)R 10 , CO 2 (C 1-6 alkyl), S(O) 2 (C 1-6 alkyl), NHS(O) 2 (C 1-6 alkyl) and S(O) 2 NR 13 R 14 , C 3-6 cycloalkyl, C 1-6 alkoxy substituted with at least one of halogen, C 1-6 alkoxy, hydroxy, C(O)R 10 , CO 2 (C 1-6 alkyl), NHC(O)O(C 1-6 alkyl) and NH 2 , C 2-6 alkenyl, C 1-6 alkoxycarbonyl, NR 6 R 7 , C 3-6 cycloalkylamino, C 1-6 alkylthio, C 1-6 alkylcarbonylamino, C(O)NR 8 R 9 , sulphonamido (S(O) 2 NH 2 ), (di)C 1-6 alkylsulphonamido, S(O) 2 (C 1-6 alkyl), S(O) 2 (C 1-6 hydroxyalkyl), S(O) 2 NH(C 1-6 alkyl), NHC(O)(C 1-6 alkyl), NHS(O) 2 (C 1-6 alkyl), phenyl, phenylamino, nitrophenyl, pyridyl, pyridylthio, benzodioxanyl, thienyl, furanyl, pyrrolyl or Δ 3 -pyrrolinyl; R 10 is hydroxy or NR 11 R 12 group; and, R 6 , R 7 R 8 , R 9 , R 11 , R 12 , R 13 and R 14 are independently hydrogen or C 1-6 alkyl; or a pharmaceutically acceptable salt thereof; or a solvate thereof.