Patent ID: 7863329

Claim:
A compound structurally represented by Formula I or a pharmaceutically acceptable salt thereof wherein; R1 and R2 are independently â€”H or -halogen; R3 is â€”(C 1 -C 8 )alkyl (optionally substituted with 1 to 3 halogens), â€”(C 3 -C 7 )cycloalkyl, â€”(C 1 -C 6 )alkyl-(C 3 -C 7 )cycloalkyl, or â€”(C 3 -C 7 )cycloalkyl-(C 1 -C 6 )alkyl (optionally substituted with 1 to 3 halogens); R4 and R5 are independently â€”H, -halogen, -hydroxy, -hydroxymethyl, â€”CN, â€”(C 1 -C 7 )alkoxy, â€”(C 2 -C 7 )alkenyl, or â€”(C 1-C 6 )alkyl (optionally substituted with 1 to 3 halogens); R6 is â€”H, -halogen, or wherein the zig-zag mark shows the point of attachment to the parent molecule; R7 and R8 are independently â€”H, -halogen, â€”(C 1 -C 6 )alkyl (optionally substituted with 1 to 3 halogens), â€”(C 1 -C 6 )alkoxy, â€”(C 3 -C 7 )cycloalkyl, â€”C(O)R10, â€”COOR10, â€”OC(O)R10, â€”OS(O) 2 R10, â€”SR10, â€”S(O)R10, â€”S(O) 2 R10, or â€”O(C 2 -C 7 )alkenyl; R9 is independently â€”H, -halogen, â€”CN, â€”(C 3 -C 7 )cycloalkyl, â€”C(O)R10, â€”COOR10, â€”OC(O)R10, â€”OS(O) 2 R10, â€”SR10, â€”S(O)R10, â€”S(O) 2 R10, or â€”O(C 2 -C 7 )alkenyl, â€”(C 1 -C 3 )alkoxy (optionally substituted with 1 to 3 halogens), or â€”(C 1 -C 6 ) alkyl (optionally substituted with 1 to 3 halogens), and R10 is independently at each occurrence -hydrogen, or â€”(C 1 -C 6 )alkyl (optionally substituted with 1 to 3 halogens).