Patent ID: 7696352

Claim:
A compound of Formula (I) or a pharmaceutically acceptable salt, ester thereof: wherein: R 1 is halogen; R 2 is hydrogen or C 1-4 alkyl; A is selected from the group consisting of: wherein the wavy line indicates the point of attachment to ring B and the dashed line indicates the point of attachment to the rest of the molecule; R 3 is hydrogen or R 3a ; R 3a is selected from the group consisting of halogen, C 1-8 alkyl, C 2-8 alkenyl, and C 2-8 alkynyl; X is C-R 4 or N; Y is C-R 5 or N provided that X and Y are not both N; R 4 is selected from the group consisting of hydrogen, halogen, and R 4a is hydrogen or C 1-8 alkyl; R 5 is selected from the group consisting of hydrogen, halogen, and C 1-8 alkoxy; R 6 is selected from the group consisting of —R 6a , —NR 7a R 7b , —NR 7a C(O)R 7c , —NR 7a C(O)OR 7c , —CONR 8a R 8b , —OR 7c , —SR 7c , —C(═NR 7a )NR 8a R 8b , —S(O) 2 NR 8a R 8b , and —S(O) 2 R 7c ; R 6a is selected from the group consisting of wherein R 8 can be at any position suitable for a substituent, and if R 8 is attached to a nitrogen atom, then it replaces the hydrogen atom attached thereto; R 7a and R 7b are independently selected from the group consisting of hydrogen, C 1-8 alkyl, and C 1-8 alkyl substituted with one to three R 9 ; R 7c is selected from the group consisting of aryl, heteroaryl, C 1-8 alkyl, and C 1-8 alkyl substituted with one to three R 9 ; R 8 is independently selected from the group consisting of nitro, hydroxyl, —CO 2 H, —C(O)R 8c , —C(O)NR 8a R 8b , —NR 8a R 8b , —SO 2 NR 8a R 8b , halogen, C 1-8 alkyl, and C 1-8 alkoxy wherein said C 1-8 alkyl and C 1-8 alkoxy are optionally substituted with one to three R 9 ; R 8a and R 8b are independently selected from the group consisting of hydrogen, C 1-8 alkyl, and C 1-8 alkyl substituted with one to three R 9 , or R 8a and R 8b together form a 5 to 7 membered heterocyclic ring optionally substituted with one to three R 9 ; R 8c is selected from the group consisting of C 1-8 alkyl and C 1-8 alkyl substituted with one to three R 9; R 9 is independently selected from the group consisting of halogen, 6-membered nitrogen-containing heterocyclic optionally containing an O atom, 5-membered nitrogen-containing heteroaryl, —OH, —R 10 , —OR 10 , —SR 10 , —S(O)R 10 , —S(O) 2 R 10 , —SO 2 NH 2 , —C(O)NH 2 , —C(O)R 10 , —C(NH)R 10 , —NHC(O)R 10 , —NHC(NH)R 10 , —NHC(O)NH 2 , —CO 2 H, —NH 2 , —NHR 10 , —N(R 10 ) 2 and —N(R 10 ) 3 + ; each R 10 is independently C 1-6 alkyl; and n is 0, 1, 2, or 3.