Patent ID: 7776875

Claim:
A compound of the formula wherein X is Cl, F or Br, X′ is hydrogen or F, V is F, Cl or Br, V′ is hydrogen or F, Y is hydrogen, methyl, methoxy, F or Cl, W is F, Cl, Br, I, ethynyl or isopropenyl, A is O, NH, CH 2 , C(═O), C(═O)NH, NHC(═O) or NHS(═O) 2 , B is a bond or (CH 2 ) m CR 1 R 2 (CH 2 ) n , m=0 or 1, n=0 or 1, R 1 , R 2 are hydrogen or lower alkyl, and in the case of R 1 and R 2 they may independently link to form a cyclic structure selected from a substituted or unsubstituted cycloalkyl, provided that if B is a bond, then R is selected from heterocycle, substituted heterocyle, heteroaryl, substituted heteroaryl, aryl or substituted aryl, if B is not a bond, then R is selected from OR″, NR′R″, C(═O)NR′R″, NHC(═O)R″, NHS(═O) 2 R″, NHC(═O)NR′R″ or C(═O)NR′S(═O) 2 R″, R′, R″ is independently selected from the group consisting of hydrogen, lower alkyl, aryl, lower alkenyl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, cycloalkyl and substituted cycloalkyl with the proviso that R″ is not a hydrogen, and in the case of R′ and R″ they may independently link to form a cyclic structure selected from substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl or substituted or unsubstituted heterocycle and the pharmaceutically acceptable salts and enantiomers thereof.