Patent ID: 6943169

Claim:
A compound of the formula: and pharmaceutically acceptable salts or prodrugs thereof, wherein: m is from 0 to 4; p is from 1 to 3; q is from 1 to 3; r is from 1 to 3; A is optionally substituted arylene; E is N; X is —CR a R b — wherein R a and R b each independently is hydrogen or alkyl; each R 1 independently is halo, alkyl, haloalkyl, hydroxy, nitro, alkoxy, cyano, —S(O) s R c , —NR c R d , —C(═O)—NR c R d , —SO 2 —NR c R d —N(R c —C(═O)—R d or —C(═O)—R c , wherein s is from 0 to 2 and R c and R d each independently is hydrogen or alkyl; Y is —(CR 2 R 3 ) n — wherein n is 1 or 2 and R 2 and R 3 each independently is hydrogen or alkyl, or X and Y together form a —CH═CH— group; R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 each independently is hydrogen or alkyl; and R 10 is hydrogen, alkyl, arylalkyl, or aryloxyalkyl.