Patent ID: 8535687

Claim:
A method of inducing a protective immune response in a mammal to pox virus, including a neutralizing antibody response, comprising: injecting into tissue of said mammal by intradermal injection a DNA vaccine comprising eight distinct DNA plasmids, wherein one DNA plasmid comprises a nucleotide sequence that encodes A4L, one DNA plasmid comprises a nucleotide sequence that encodes A27L, one DNA plasmid comprises a nucleotide sequence that encodes B5R, one DNA plasmid comprises a nucleotide sequence that encodes A33R, one DNA plasmid comprises a nucleotide sequence that encodes A56R, one DNA plasmid comprises a nucleotide sequence that encodes F9L, one DNA plasmid comprises a nucleotide sequence that encodes H3L, and one DNA plasmid comprises a nucleotide sequence that encodes L1R; and electroporating said tissue with an electroporating amount of electrical energy.