Patent ID: 8783866

Claim:
A scanning Fourier Domain (FD) optical coherence tomography (OCT) imaging system for imaging structures posterior to a lens of an eye of a rodent subject, the system comprising: a source having an associated source arm path; a reference arm having an associated reference arm path coupled to the source arm path, the reference arm path having an associated reference arm path length; a sample arm having an associated sample arm path coupled to the source arm path, the sample arm comprising: an input optical fiber delivering optical radiation from the source; at least one optical element following the input optical fiber; at least one scanning mirror following the at least one optical element; and imaging optics following the at least one scanning mirror, the imaging optics including a plurality of lens elements; a reference arm path length adjustment module coupled to the reference arm, wherein the imaging optics of the sample arm images a conjugate of the at least one scanning mirror to a region posterior to the cornea of the rodent subject and anterior to a retina of the rodent subject; wherein the imaging optics of the sample arm focus the optical radiation from the input optical fiber to a substantially telecentric conjugate plane, wherein a final objective lens relays a conjugate of the optical radiation from the source to a region posterior to the imaging position of the at least one scanning mirror and substantially within a region of the retina; and wherein the reference arm is adjusted to position an OCT image of the retina of the rodent subject within a Fourier domain imaging window.