Patent ID: 8202240

Claim:
An integrated pre-connected disposable set for separating whole blood into plasma protein fractions comprising: a first hollow fiber membrane separator having an inlet and a first outlet for separating whole blood into plasma and other blood components; a plasma collect tubing pre-connected to the first outlet of the first membrane separator; a plasma protein collection container; and a second hollow fiber membrane separator comprising an inlet pre-connected to the plasma collect tubing; and a first outlet connected to the plasma protein collection container to connect the second hollow fiber membrane separator between the first outlet of the first hollow fiber membrane separator and the plasma protein collection container wherein separated plasma exiting the first hollow fiber membrane separator from the first membrane first outlet passes through the collect tubing to the second hollow fiber membrane separator for separation into desired plasma proteins and wherein such plasma proteins are collected in the plasma protein collection container; wherein the set further comprises a cassette having internal passageways for fluidly connecting the first membrane separator to the second membrane separator.