Patent ID: 8268840

Claim:
A compound of formula I including enantiomers, diastereomers, racemic mixtures and pharmaceutically acceptable salts thereof, wherein: R 1 is R 1a or R 1b ; R 1a is H, halo, acyl, lower alkyl, lower haloalkyl, lower alkoxy, —CN, or —OH; R 1b K is cycloalkyl, heterocycloalkyl, or phenyl, optionally substituted with one or more R 1b′ ; each R 1b′ is independently halo, —OH, lower alkoxy, amino, lower alkyl or lower haloalkyl; R 2 is lower alkyl, lower heteroalkyl, lower alkoxy, cycloalkyl, phenyl, heterocycloalkyl, or heteroaryl, optionally substituted with one or more R 2a ; each R 2a is independently —OH, halo, lower alkyl, amino, lower alkoxy, or R 2b ; R 2b is cycloalkyl, heterocycloalkyl, or phenyl, optionally substituted with one or more R 2b′ ; each R 2 b′ is independently halo, —OH, lower alkoxy, amino, lower alkyl or lower haloalkyl; R 3 is halo, amino, lower alkyl, lower alkoxy, or lower haloalkyl; A is O or A′; A′ is C(R 5 )(R 5′ ) or N(R 5b ); R 5 and R 5′ are independently R 5a or R 5b ; R 5a is —H, halo, —OH, or A″; R 5b is lower alkyl, A″, or lower heteroalkyl, optionally substituted with one or more R 6a ; R 6a is —OH, halo, lower alkyl, lower haloalkyl, lower alkoxy, or amino; A″ is —NHC(═O)R 7 , —NHC(═O)OR 7 , —N(R 9 )S(═O) 2 R 7 , —S(═O) 2 R 7 , —C(═O)R 8 , or —C(═O)OR 7 ; R 7 is lower alkyl or cycloalkyl; R 8 is cycloalkyl, cycloalkyl lower alkyl, heterocycloalkyl, heterocycloalkyl lower alkyl, or lower alkyl, each of which may be optionally substituted with halo, —OH, lower alkoxy, amino, or lower alkyl; R 9 is H or lower alkyl; and m is 0 to 4.