Patent ID: 7252949

Claim:
A method for determining whether a patient in need of a blood transfusion needs to be transfused with RhD negative blood comprising the step of testing a sample from said patient for the presence of a nucleic acid molecule carrying at least one missense mutation, as compared to SEQ ID NO:41, selected from any one of the following nucleic acid molecules, with reference to SEQ ID NO:41: in position 8 is from C to G, in position 29 from G to A, in position 48 from G to C, in position 340 from C to T, in position 446 from C to A, in position 544 from T to A, in position 594 from A to T, in position 602 from C to G, in position 658 from T to C, in position 667 from T to G, in position 809 from T to G, in position 819 from G to A, in position 826 from G to C, in position 830 from G to A, in position 845 from G to A, in position 880 from G to C, in position 885 from G to T, in position 919 from G to A, in position 1016 from G to A. in position 1154 from G to C and in position 1177 from T to C, wherein a positive testing for at least one of said missense mutations indicates that the patient needs to be transfused with RhD negative blood.