Patent ID: 8623372

Claim:
A method for preventing the development of attaching and effacing (A/E) intestinal lesions associated with an attaching and effacing Escherichia coli (AEEC) in a mammal, said method comprising: passive immunization by oral administration to the mammal of IgY antibodies immunologically specific to AEEC virulence-associated proteins, wherein the IgY antibodies are a mixture of an IgY antibody immunologically specific to porcine attaching-effacing associated protein Paa and one or more IgY antibodies immunologically specific to an AEEC virulence-associated protein selected from the group consisting of intimin (Eae), translocated intimin receptor (Tir) and secreted protein EspA, and wherein the antibodies prevent the development of A/E intestinal lesions associated with an AEEC in the mammal.