Patent ID: 7902159

Claim:
A method for ameliorating an infectious disease, autoimmune disease or allergic condition in a subject in need thereof comprising contacting the subject with an effective amount of one or more compounds having the formula: and pharmaceutically acceptable salts thereof, wherein X is a member selected from the group consisting of —O— and —NH—; R 1 and R 2 are each members independently selected from the group consisting of (C 2 -C 24 )acyl; R 3 is a member selected from the group consisting of —H and —PO 3 R 11 R 12 , wherein R 11 and R 12 are each members independently selected from the group consisting of —H and (C 1 -C 4 )alkyl; R 4 is a member selected from the group consisting of —H, —CH 3 and —PO 3 R 13 R 14 , wherein R 13 and R 14 are each members independently selected from the group consisting of —H and (C 1 -C 4 )alkyl; and Y is a radical having the formula: wherein the subscripts n, m, p and q are each independently an integer of from 0 to 6; R 5 is (C 2 -C 24 )acyl; R 6 and R 7 are members independently selected from the group consisting of H and CH 3 ; R 8 and R 9 are members independently selected from the group consisting of H, OH, (C 1 -C 4 )alkoxy, —PO 3 H 2 , —OPO 3 H 2 , —SO 3 H, —OSO 3 H, —NR 15 R 16 ,—SR 15 , —CN, —NO 2 ,—CHO, —CO 2 R 15 , —CONR 15 R 16 , —PO 3 R 15 R 16 , —OPO 3 R 15 R 16 , —SO 3 R 15 and —OSO 3 R 15 wherein R 15 and R 16 are each members independently selected from the group consisting of H and (C 1 -C 4 )alkyl; and Z is —O— or —S—; with the proviso that when R 3 is —PO 3 R 11 R 12 , R 4 is other than —PO 3 R 13 R 14 , wherein the one or more compounds is administered in the absence of exogenous antigen.