Patent ID: 8846672

Claim:
A compound satisfying formula I, a prodrug, N-oxide, addition salt, quaternary amine, metal complex, or a stereochemically isomeric form thereof; wherein each X independently is C or N; each Y independently is C or N; R 1 is present when X═C and R 1 is selected from the group of H, halogen, C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 1 -C 6 alkoxy, N(R 5 ) 2 , CO(R 6 ), CH 2 NH 2 , CH 2 OH, CN, C(═NOH)NH 2 , C(═NOCH 3 )NH 2 , C(═NH)NH 2 , CF 3 , OCF 3 , and B(OH) 2 ; B (O—C 1 -C 6 alkyl) 2 ; R 1 is absent when X=N R 2 is selected from the group consisting of halogen, —(CR 7 R 8 ) n —R 9 , C≡C—CH 2 —R 9 , C≡C—R 9 , and C═C—R 9 R 3 is selected from the group consisting of H, C 1 -C 10 alkyl, C 3 -C 7 cycloalkyl, C 2 -C 10 alkenyl, SO 2 —R 7 , or a 4 to 6 membered saturated ring containing an oxygen atom; R 4 is present where Y is C and is selected from the group consisting of H, C 1 -C 6 alkyl, C 1 -C 6 cycloalkyl, C 1 -C 6 alkoxy, CO(R 7 ), CF 3 and halogen, R 4 is absent when Y=N; R 5 is selected from the group consisting of H, C 1 -C 6 alkyl, COOCH 3 , and CONHSO 2 CH 3 ; R 6 is selected from the group consisting of OH, O(C 1 -C 6 alkyl), NH 2 , NHSO 2 N(C 1 -C 6 alkyl) 2 , NHSO 2 NHCH 3 , NHSO 2 (C 1 -C 6 alkyl), NHSO 2 (C 3 -C 7 cyclo-alkyl), and N(C 1 -C 6 -alkyl) 2 ; R 7 and R 8 are each independently chosen from H, C 1 -C 10 alkyl, C 3 -C 7 cycloalkyl or R 7 and R 8 taken together form a 4 to 6 membered aliphatic ring that optionally contains at least one heteroatom selected from the group N, S, O; R 9 is selected from the group consisting of H, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 3 -C 7 cycloalkyl OH, CN, F, CF 2 H, CF 3 , CONR 7 R 8 , COOR 7 , CON(R 7 )SO 2 R 8 , CON(R 7 )SO 2 N(R 7 R 8 ), NR 7 R 8 , NR 7 COOR 8 , OCOR 7 , NR 7 SO 2 R 8 , SO 2 NR 7 R 8 , SO 2 R 7 or a 4 to 6 membered saturated ring containing an oxygen atom; n is an integer from 2 to 6.