Patent ID: 8821919

Claim:
A method for debridement of a wound on a soft tissue site of a mammalian host comprising: placing a first glass-based composition comprising from about 40 to about 90 wt % B 2 O 3 against an area of the wound comprising non-viable tissue comprising black necrotic eschar; retaining the first glass-based composition against said area of the wound; replacing the composition by removing the first glass-based composition from against said area of the wound and placing against said area of the wound a subsequent glass-based composition also comprising a glass-based composition comprising from about 40 to about 90 wt % B 2 O 3 ; and repeating said replacing and retaining steps so that said retaining is performed cumulatively for a period of at least 24 hours, said repeating of the replacing and retaining steps resulting in removal of the black necrotic eschar.