Patent ID: 7172900

Claim:
Isolated CD8+ T cells that are specifically cytotoxic for a disease causing target cell, wherein the target cell has on its surface one or more non-tumor self antigen T cell epitopes associated with Class I MHC molecules, wherein said self-antigen T cell epitopes are epitopes present on IgE protein and are selected from the group consisting of TQSPSVFPL (SEQ ID NO:64), SLNGTTMTL (SEQ ID NO:50), TMTLPATTL (SEQ ID NO:69), TLPATTLTL (SEQ ID NO:67), TLSGHYATI (SEQ ID NO:68), WVDNKTFSV (SEQ ID NO:51). WLSDRTYTC (SEQ ID NO:52), ALMRSTTKT (SEQ ID NO:65), NFMPEDISV (SEQ ID NO:79), YATISLLTV (SEQ ID NO:58), TLTVTSTLPV (SEQ ID NO:56), SVQWLHNEV (SEQ ID NO:76), QWLHNEVQL (SEQ ID NO:80), TLACLIQNFM (SEQ ID NO:59), or QVMDVDLSTA (SEQ ID NO:60), and wherein the CD8+ T cells have been selectively activated by culturing said CD8+ T cells in the presence of antigen presenting cells (APC) having Class I MHC molecules and wherein said APC are loaded with one of said non-tumor self antigen T cell epitopes.