Patent ID: 8653091

Claim:
A compound according to formula 1a: wherein R 1 is cycloalkyl, cycloheteroalkyl, or heteroaryl unsubstituted or substituted with one or more R 4 groups; R 2 is substituted or unsubstituted C 1 -C 6 alkyl or cycloalkyl; R 3 is halo, substituted or unsubstituted C 1 -C 6 alkyl or cycloalkyl; each R 4 is independently selected from the group consisting of H, alkyl, acyl, acylamino, alkylamino, alkythio, alkoxy, alkoxycarbonyl, alkylarylamino, arylalkyloxy, arylalkyloxy, amino, aryl, arylalkyl, sulfo, substituted sulfo, substituted sulfonyl, substituted sulfinyl, substituted sulfanyl, azido, carbamoyl, carboxyl, cyano, cycloalkyl, cycloheteroalkyl, dialkylamino, halo, heteroaryloxy, heteroaryl, heteroalkyl, hydroxy, nitro, and thiol; or a pharmaceutically acceptable salt, solvate, prodrug, tautomer or isotopic variant thereof.