Patent ID: 8680101

Claim:
A pharmaceutical composition containing crystalline pimobendan, the structural formula of which is: wherein the pharmaceutical composition includes no organic acid that is therapeutically inactive, and wherein the crystalline pimobendan is selected from the group consisting of: (i) form A, the diffraction pattern using powder X-ray diffractometry of which has peaks at Bragg angles (2θ) of 12,69°, 18,67° and 19,42°, with relative intensities of 9%, 100% and 37%, respectively, as the most characteristic peaks; (ii) form B, the diffraction pattern using powder X-ray diffractometry of which has peaks at Bragg angles (2θ) of 4,65°, 12,90° and 20,70°, with relative intensities of 100%, 53% and 99%, respectively, as the most characteristic peaks: (iii) form C, a dioxane solvate, of which the diffraction pattern using powder X-ray diffractometry of which has peaks at Bragg angles (2θ) of 7,88°, 14,45° and 17,94°, with relative intensities of 100%, 58% and 49%, respectively, as the characteristic peaks; (iv) form D, a methanol solvate, of which the diffraction pattern using powder X-ray diffractometry of which has peaks at Bragg angles (2θ) of 11,20°, 12,82° and 20,80°, with relative intensities of 70%, 94% and 100%, respectively, as the most characteristic peaks.