Patent ID: 7527947

Claim:
A method for producing a secreted polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of a secreted polypeptide, wherein the host cell comprises a nucleic acid construct comprising a first nucleotide sequence and a second nucleotide sequence, wherein said first nucleotide sequence encodes a signal peptide that either (i) consists of the amino acid sequence of SEQ ID NO:1; or (ii) consists of the amino acid sequence from position 1 through position 16 of SEQ ID NO:1; and wherein said second nucleotide sequence encodes a polypeptide foreign to the signal peptide encoded by the first nucleotide sequence and the 3′ end of the first nucleotide sequence is linked immediately to the 5′ end of the second nucleotide sequence, and (b) isolating the secreted polypeptide from the cultivation medium.