Patent ID: 6951864

Claim:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is selected from: (a) hydrogen, halogen, nitro and cyano; and (b) groups of the formula: wherein: G is a bond, C 1 -C 8 alkyl, —N(R B )—, —O—, —C(═O)—, —C(═O)N(R B )—, —N(R B )C(═O)—, —S(O) m —, —CH 2 C(═O)—, —S(O) m N(R B )— or —N(R B )S(O) m —; wherein m is 0, 1 or 2; and R A and each R B are independently selected from: (a) hydrogen; and (b) C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl and 3- to 12-membered carbocycles and heterocycles, each of which is substituted with from 0 to 4 substituents independently selected from halogen, hydroxy, nitro, cyano, amino, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, C 1 -C 4 alkanoyl, mono- and di(C 1 -C 4 alkyl)amino, C 1 -C 4 haloalkyl and C 1 -C 4 haloalkoxy; R 2 is hydrogen, halogen, hydroxy, nitro, cyano, amino, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 3 -C 7 cycloalkyl, or mono- or di-(C 1 -C 4 alkyl)amino; R 3 is hydrogen, halogen, hydroxy, nitro, cyano, amino, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 3 -C 7 cycloalkyl, C 1 -C 8 haloalkyl, C 1 -C 8 alkoxy, C 1 -C 8 haloalkoxy, C 2 -C 8 alkyl ether, C 2 -C 8 haloalkyl ether, or mono- or di-(C 1 -C 8 alkyl)amino; R 4 represents 0, 1 or 2 substituents independently chosen from halogen, hydroxy, nitro, cyano, amino, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, mono- and di(C 1 -C 4 alkyl)amino, C 3 -C 7 cycloalkyl, C 1 -C 2 haloalkyl and C 1 -C 2 haloalkoxy; Ar represents phenyl, naphthyl or 5- to 10-membered heteroaryl, each of which is substituted with from 0 to 4 substituents independently selected from halogen, hydroxy, nitro, cyano, amino, C 1 -C 8 alkyl, C 1 -C 8 alkenyl, C 1 -C 8 alkynyl, C 3 -C 7 cycloalkyl(C 0 -C 8 alkyl), C 1 -C 8 haloalkyl, C 1 -C 8 alkoxy, C 3 -C 7 cycloalkyl(C 1 -C 8 alkoxy), C 1 -C 8 haloalkoxy, C 1 -C 8 alkyl ether, C 1 -C 8 alkanone, C 1 -C 8 alkanoyl, 3- to 7-membered heterocycloalkyl(C 0 -C 8 alkyl), oxo, C 1 -C 8 hydroxyalkyl, C 1 -C 8 aminoalkyl, and mono- and di-(C 1 -C 8 alkyl)amino(C 0 -C 8 alkyl); and R 5 and R 6 are independently hydrogen, halogen, methyl or ethyl.