Patent ID: 7972781

Claim:
A screening method for detecting or assessing degree of risk of cancer in an individual human comprising collecting samples of cellular and extracellular materials from selected areas of the body of said individual and analyzing said samples for elevated free levels of nucleotide excision products in the extracellular as compared to the cellular material, wherein the nucleotide excision products analyzed are selected from the group consisting of 8-hydroxy-2′-deoxyguanosine, O-6-methylguanine, 2′-deoxyguanosine, 7-methylguanine, 8-nitroguanine, 8-hydroxyguanine, dA-8-hydroxy-2-deoxyadenosine, 8-hydroxyandenine, 5-hydroxy-2′-deoxycytidine, 5-hydroxyuracil, 3-nitrotyrosine and 3-chlorotyrosine, and wherein increased levels of said nucleotide excision products indicate detection or degree of risk of cancer of said selected body areas, and generating a signal based on said analysis.