Patent ID: 7632845

Claim:
A method of lowering cholesterol, triglycerides, Lp(a), or LDL levels; or inhibiting hypercholesteremia; or hyperlipidemia; comprising providing to said mammal an effective amount of a compound of the formula: wherein: A and A′ are each, independently, OH or OP; P is alkyl, alkenyl, benzyl, acyl, aroyl, alkoxycarbonyl, sulfonyl or phosphoryl; R 1 and R 2 are each, independently, H, halogen, C 1 -C 6 alkyl, C 2 -C 7 alkenyl, or C 1 -C 6 alkoxy; R 3 is H, halogen, or C 1 -C 6 alkyl; R 4 , R 5 and R 6 are each, independently, H, halogen, C 1 -C 6 alkyl, C 2 -C 7 alkenyl, C 2 -C 7 alkynyl, C 3 -C 7 cycloalkyl, C 1 -C 6 alkoxy, —CN, —CHO, acyl, phenyl, aryl or heteroaryl; wherein the alkyl or alkenyl moieties of R 4 , R 5 or R 6 may be optionally substituted with halogen, OH, —CN, trifluroalkyl, trifluoroalkoxy, —NO 2 , or phenyl; wherein the alkynyl moiety of R 4 , R 5 or R 6 may be optionally substituted with halogen, —CN, —CHO, acyl, trifluroalkyl, trialkylsilyl, or optionally substituted phenyl; wherein the phenyl moiety of R 4 , R 5 or R 6 may be optionally mono-, di-, or tri-subsitituted with halogen, C 1 -C 6 alkyl, C 2 -C 7 alkenyl, OH, C 1 -C 6 alkoxy, —CN, —CHO, —NO 2 , amino, C 1 -C 6 alkylamino, di-(C 1 -C 6 )alkylamino, thiol, or C 1 -C 6 alkylthio; or a N-oxide thereof or a pharmaceutically acceptable salt thereof or a prodrug thereof.