Patent ID: 8586062

Claim:
A solution consisting of (a) a taxane derivative selected from paclitaxel or docetaxel (b) a polymer selected from the group consisting of polyvinylpyrrolidone, polyglutamic acid or its salts and hyaluronic acid or its salts, (c) a surfactant consisting of a mixture of caprylic acid or its salts and cholesteryl sulphate or its salts, and (d) a water miscible solvent selected from the group consisting of alcohol, polyethylene glycol and polypropylene glycol, such that dilution of the solution with an aqueous liquid vehicle or vice versa, with agitation or shaking results in the formation of a nanodispersion that remains stable for at least 4 hours with no aggregation or crystallization of the taxane derivative, and wherein the nanodispersion is administered to a patient by intravenous infusion.