Patent ID: 7842818

Claim:
A method for producing a compound represented by formula (VII): wherein R represents an aryl group which may have a substituent, an aralkyl group which may have a substituent, a C1 to C6 alkyl group which may have a substituent, or a chiral auxiliary which can form an ester bond with carboxylic acid; and R 1 represents an aralkyl group which may have a substituent, which comprises: reacting a compound represented by formula (I): wherein R and R 1 have the same meanings as defined above, with a methylating reagent in the presence of a base to produce a compound represented by formula (II): wherein R 1 and R have the same meanings as defined above; reacting the compound represented by formula (II) with a compound represented by formula (III): wherein R′ represents a protective group for hydroxy group, and X represents a halogen atom or a leaving group employed in nucleophilic substitution, in the presence of a base to produce a compound represented by formula (IV): wherein R 1 , R, and R′ have the same meanings as defined above; removing the protective group for hydroxy group from the compound represented by formula (IV) to produce a compound represented by formula (V): wherein R 1 and R have the same meanings as defined above; transforming the hydroxy group of the compound represented by formula (V) to a halogen atom or a leaving group employed in nucleophilic substitution to form a compound represented by formula (VI): wherein Y represents a halogen atom or a leaving group employed in nucleophilic substitution, and R 1 and R have the same meanings as defined above; and treating the compound represented by formula (VI) under basic conditions.