Patent ID: 8524272

Claim:
A storage-stable device for the release of an active agent to the skin or mucosa of a host, said device consisting of: an outer patch having adhesive properties; an inner patch comprising an active agent layer containing an active agent and a coextensive active agent impermeable layer supporting the active agent layer, the active agent impermeable layer having a first surface in contact with the active agent layer and a second surface opposing the first surface; and, a release liner interposed between the inner patch and the outer patch, the release liner releasably adhered to a first adhesive portion of the outer patch and having an opening exposing a second adhesive portion of the outer patch to the inner patch, wherein, prior to removal of the release liner for application of the device to the skin or mucosa of a host, a portion of the second surface of the active agent impermeable layer is adhered to the second adhesive portion of the outer patch exposed by the opening in the interposed release liner, and a remaining portion of the second surface of the active agent impermeable layer is unadhered to the first or second adhesive portion of the outer patch as a result of the release liner being interposed therebetween prior to the removal of the release liner for the application of the device; and, the outer patch having a surface area greater than the surface area of the inner patch, such that removal of the release liner for the application of the device adheres the remaining portion of the active agent impermeable layer to the adhesive layer of the outer patch and exposes another adhesive portion of the outer patch extending beyond the periphery of the inner patch for adhering the device to the skin or mucosa of a host; and a second release liner releasably adhered to said inner patch.