Patent ID: 8492341

Claim:
A peptide capable of binding Aβ and disrupting its superoxide dismutase (SOD) activity and/or metal ion binding, wherein the peptide is selected from the group consisting of: (i) a peptide consisting of the amino acid sequence: Asn-Arg-Thr-Pro-Gln-Met-Leu-Lys-Arg (SEQ ID NO:2); (ii) a truncated form of the peptide (i) of at least 7 contiguous amino acids of SEQ ID NO:2; (iii) a peptide of 5, 6, 7, 8, or 9 amino acids, wherein the peptide sequence is at least 70% identical to SEQ ID NO:2; (iv) a peptide of 5, 6, 7, 8, or 9 amino acids, wherein the peptide sequence is at least 80% identical to SEQ ID NO:2; and (v) a peptide of 5, 6, 7, 8, or 9 amino acids, wherein the peptide sequence is at least 90% identical to SEQ ID NO:2.