Patent ID: 8828982

Claim:
A method for the efficient blocking of transmission of HIV infection via sexual intercourse or related intimate contact between partners, said method comprising application to a contact site an effective amount of a compound having the formula an N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine or a stereochemically isomeric form thereof; wherein n′ is 0 or 1; m is 1 or 2; R 4 is independently C 1-6 alkyl, nitro, amino, halo, or C 1-6 alkyloxy; R 3 is C 1-6 alkyl substituted with cyano or C 2-6 alkenyl substituted with cyano; X 1 is —NH— or —O—; R 1 is hydrogen; R 2 is cyano; and R 2′ is halo, C 1-6 alkyl, trihalomethyl, trihalomethyloxy, cyano, aminocarbonyl, C 1-6 alkyl substituted with cyano or aminocarbonyl.