Patent ID: 8871726

Claim:
A compound represented by the following general formula (I): wherein: X is O or S; each of R 1 and R 2 is independently hydrogen, —OH, —SH, —NH 2 , —NO 2 , —CN, —COH, —COOH, —CONH 2 , halogen, C 1 -C 4 alkyl, —O—C 1 -C 4 alkyl, —S—C 1 -C 4 alkyl, —SO—C 1 -C 4 alkyl, —SO 2 —C 1 -C 4 alkyl, —CO—C 1 -C 4 alkyl, —CO 2 —C 1 -C 4 alkyl, —CONH—C 1 -C 4 alkyl, —C≡C—C 1 -C 4 alkyl, —NHSO 2 —C 1 -C 4 alkyl, —NHCO—C 1 -C 4 alkyl or —C 3 -C 6 cycloalkyl; R 3 is hydrogen, —OH, —SH, —NH 2 , —NO 2 , —CN, —COH, —COOH, —CONH 2 , halogen, —C 1 -C 4 alkyl, —O—C 1 -C 4 alkyl, —S—C 1 -C 4 alkyl, —CO—C 1 -C 4 alkyl, —CO 2 —C 1 -C 4 alkyl, —CONH—C 1 -C 4 alkyl, an aryl having 1-3 substituents selected from the groups in Group A, a heteroaryl having 1-3 substituents selected from the groups in Group A, a C3-C8cycloalkyl having 1-3 substituents selected from the groups in Group A, a nitrogen-containing saturated heterocyclic group having 1-3 substituents selected from the groups in Group A or a nitrogen-containing partially unsaturated heterocyclic group having 1-3 substituents selected from the groups in Group A, wherein, the group in Group A is selected from the group consisting of: hydrogen, halogen, —OH, —SH, —NH 2 , —NO 2 , —CN, —COH, —COOH, —CONH 2 , C 1 -C 4 alkyl, —O—C 1 -C 4 alkyl, —NH—C 1 -C 4 alkyl, —S—C 1 -C 4 alkyl, —SO 2 —C 1 -C 4 alkyl, —CO—C 1 -C 4 alkyl, —CO 2 —C 1 -C 4 alkyl, —CONH—C 1 -C 4 alkyl, —CONH—C 3 -C 6 cycloalkyl, —C 1 -C 4 alkyl-OH, -aryl, —O-aryl, —NH-aryl, —S-aryl, —SO 2 -aryl, —CO-aryl, —CO 2 -aryl, —CONH-aryl, -cycloalkyl, -heteroaryl, -a nitrogen-containing saturated heterocyclic group, —C 1 -C 4 alkyl-a nitrogen-containing saturated heterocyclic group and -a nitrogen-containing partially unsaturated heterocyclic group; R 4 is —O—R 5 , —S—R 5 , —SO—R 5 , —SO 2 —R 5 , R 5 is —C 1 -C 4 alkyl or —C 3 -C 8 cycloalkyl; m is 1, 2 or 3; and n is 1 or 2, or a pharmaceutically acceptable salt thereof.