Patent ID: 8163730

Claim:
A compound of formula (1a′): wherein R 2 is hydrogen, alkyl, cycloalkyl, nitro, or NR 11 R 12 ; R 4 and R 5 are each independently selected from: hydrogen, halogen, hydroxy, trifluoromethyl, alkyl, cycloalkyl, alkenyl and alkoxy; R 7 is —(CH 2 ) n C(O)R 9 ; R 9 is hydrogen, halogen, alkyl, cycloalkyl, trifluoromethyl or OR 10 , R 10 is hydrogen, alkyl or cycloalkyl; R 11 and R 12 are each independently selected from: hydrogen, alkyl, cycloalkyl or —(CH 2 ) n C(O)R 9 ; R 15 is H or alkyl; and n is 0, 1 or 2; where alkyl or cycloalkyl is unsubstituted or substituted by one or two of the same or different groups selected from: halogen, hydroxy, alkylcarboxy, amino, cycloalkyl, alkoxy, aryloxy, alkoxylcarbonyl, arylalkoxycarbonyl, aminocarbonyl, alkylamino, dialkylamino, cycloalkylamino, cycloalkylalkylamino, heterocyclylalkylamino, heteroaryl, heteroarylamino, heteroarylalkylamino, dialkylaminoalkylamino, aryl, aminoaryl, heteroaryl and heterocyclyl; in all its stereoisomeric and tautomeric forms and mixtures thereof in all ratios, and its pharmaceutically acceptable salts and solvates.