Patent ID: 7303924

Claim:
A method of functionalising a solid support comprising, at the surface, hydroxyl or hydride functions comprising the following steps: a) grafting by covalent attachment at least one bifunctional molecule comprising a protected carboxylic acid function of formula (I) below: A—X—COOR (I) in which: A represents a group which allows the covalent attachment of the bifunctional molecule of formula (I) to the hydroxyl or hydride functions of the support, R represents a group for protecting the carboxylic acid function, X represents a saturated or unsaturated, linear or branched C 2 -C 18 hydrocarbon-based chain; b) deprotecting the carboxylic acid functions which were not deprotected during the grafting step a); and, c) passivation of the residual hydroxyl or hydride functions of the support which have not reacted with said molecule(s) of formula (I); wherein step a) is carried out at a temperature of between 50 and 200° C. with a compound of formula (I) in which A is a monofunctional group.