Patent ID: 7209781

Claim:
A method for localizing at least one lesion in a biological tissue section, said lesion exhibiting an electrical property different from said tissue section, and said electrical property in said tissue section being substantially constant, comprising the steps of: applying a sequence of electrical excitation signals with respectively different frequencies to said tissue section; measuring electrical response signals, arising due to said excitation signals, at a plurality of measurement locations at a surface of said tissue section; determining frequency-independent signal parts in said response signals and further-processing said frequency-independent signal parts to produce input values for a localization procedure; and in said localization procedure, modeling said tissue section dependent on said input values to produce a tissue section model and from said tissue section model determining a set of lead fields, and transforming said lead fields to obtain transformed lead fields, and comparing said frequency-independent signal parts to said transformed lead fields to identify a location of said transformed lead fields that best reproduces said frequency-independent signal parts, and providing said location as an output as the location of said lesion.