Patent ID: 8110352

Claim:
A method of detecting the presence or absence of a β-catenin gene (CTNNB1) related esophageal cancer in a subject, comprising: (a) obtaining a subject sample; (b) determining the proportion of 16A transcript to 16B transcript in a cell or cells from the subject sample; (c) comparing the proportion of 16A transcript to 16B transcript to a standard proportion, (d) identifying a decrease in a 16A transcript level relative to a 16B transcript level in the subject sample; and (e) identifying the subject as having a CTNNB1 related esophageal cancer; or performing said steps (a) to (c) and (f) not identifying a decrease in a 16A transcript level relative to a 16B transcript level in the subject sample; and (g) identifying the subject as not having a CTNNB1 related esophageal cancer.