Patent ID: 8642583

Claim:
A compound selected from the group consisting of (a) compounds of Formula (I): wherein R 1 is —H, —C 1-4 alkyl, monocyclic cycloalkyl, phenyl, or benzyl; m is 1; n is 1; R 2 and R 3 are each independently —H or —C 1-4 alkyl; R 4 is —H, F, C 1-4 alkyl, or R 4 is —OH when L is —CH 2 —, —CF 2 —, —CHF—, —OCH 2 —, or —OCH(CH 3 )—; L is —O—, —CH 2 —, —OCH 2 —, —OCH(CH 3 )—, —CH 2 O—, —CF 2 —, or —CHF—; Z is —O—, —C(O)—, —OCH(R b )—, or —OCH 2 C(R c )(R d )—; where R b is —H; a —C 1-4 alkyl group unsubstituted or substituted with OH or halo: —CO 2 C 1-4 alkyl; or —CO 2 H; and R c and R d are each independently —H, —C 1-4 alkyl, —O—C 1-4 alkyl, or halo; or R c and R d taken together form an oxime, a C 1-4 alkyl oxime, or a carbonyl group; or R c and R d taken together with the carbon to which they are attached form a C 3-6 cycloalkyl group; R 5 is: i) a phenyl, unsubstituted or substituted with one, two, or three R g substituents; where each R g substituent is selected from the group consisting of: —C 1-6 alkyl, —OH, —OC 1-6 alkyl, —CN, —NO 2 , —C(O)C 1-6 alkyl, —S(O) 0-2 —C 1-6 alkyl, —OS(O) 0-2 —C 1-6 alkyl, —SO 2 CF 3 , —SCF 3 , halo, —CF 3 , —OCF 3 , —CO 2 H, —CO 2 C 1-6 alkyl, —CH 2 OH, monocyclic cycloalkyl, phenyl, thiophenyl, benzhydryl, and oxadiazolyl; or two R g substituents taken together form —OCH 2 O—, —OCF 2 O—, or —OCH 2 CH 2 O—; ii) a naphthyl group, unsubstituted or substituted with C 1-4 alkyl or halo; iii) a monocyclic heteroaryl group, unsubstituted or substituted with one, two, or three R g substituents; iv) a fused bicyclic heteroaryl group, unsubstituted or substituted with C 1-4 alkyl or halo; v) a monocyclic cycloalkyl group, optionally fused to a phenyl ring, and unsubstituted or substituted with one or two substituents selected from the group consisting of: —C 1-4 alkyl, —OC 1-4 alkyl, halo, —CF 3 , oxime, —C 1-4 alkyl oxime, or phenyl; and vi) a monocyclic heterocycloalkyl group, optionally fused to or substituted with phenyl; X is C; R 6 or R 7 are each independently —H, halo, —CF 3 , or —C(O)N(R x )R y ; wherein R x and R y are each independently —H or —C 1-4 alkyl; and (b) pharmaceutically acceptable salts of the compounds of Formula (I).