Patent ID: 7157450

Claim:
A compound of formula B—R″—X 1 —NO 2 or their esters or salts, wherein B—R″ has the following structure: R″ is —(CO—L) t —(X) t1 wherein in the place of H in the CH group or H 2 in the CH 2 group there may be the following substituents: at position 1-2: a double bond; at position 2-3 at position 2, Cl or Br; at position 3, oxo, —O—CH 2 —CH 2 —Cl, or OH; at position 4-5, a double bond; at position 5-6, a double bond; at position 6, Cl, F CH 3 , or CHO; at position 7, Cl; at position 9, Cl or F; at position 11, OH, oxo or Cl; at position 16, CH 3 , OH, or ═CH 2 ; at position 17, OH, CH 3 , OCO(O) ua (CH 2 ) va CH 3 , or wherein ua is an integer equal to 0 or 1 and va is an integer from 0 to 4; at position 16-17, R and R′ are equal or different one from the other and may be hydrogen or linear or branched alkyls having from 1 to 4 carbon atoms, wherein in R″ t and t1 are integers where t is equal to 1, t1 equals 0, 1; wherein between B and X 1 there is an ester or amide linkage; the bivalent bridging member L is selected from the group consisting of (CR 4 R 5 ) na (O) nb (CR 4 R 5 ) n′a (CO) n′b (O) n″b (CO) n′″b (CR 4 R 5 ) n″a , wherein na, n′a, and n″a are equal to or different one from the other and are integers from 0 to 6, nb, n′b, n″b and n′″b are equal to or different to each other and are equal to 0 or 1; R 4 and R 5 are equal or different one from the other and are selected from the group consisting of H, linear or branched alkyls having 1 to 5 carbon atoms, X is equal to Xo where Xo is O, NH, NR 1c where R 1c is a linear or branched alkyl having from 1 to 10 carbon atoms; X 1 is selected from the group consisting of wherein n 3 is an integer from 0 to 3; and wherein B is a residue of prednicarbate.