Patent ID: 8278327

Claim:
A method for treating schizophrenia or psychosis in a warm-blooded animal in need thereof, comprising administering to the animal an effective amount of a compound having the following structure (I): or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: m, n and p are individually 0 or 1; x is 1, 2 or 3; A is an optionally substituted heterocycle, wherein the heterocycle is quinoline; B is —O—, —NR 6 — or —S(O) z — where z is 0, 1 or 2; R is hydrogen or oxo; R 1 is absent or represents 1, 2 or 3 substituents that are the same or different and independently halogen, C 1-6 alkyl, —CHF 2 , —CF 3 , —CH 2 NH 2 , —CH 2 NH(C 1-6 alkyl) or —CH 2 N(C 1-6 alkyl) 2 ; R 2 is at each occurrence the same or different and independently, hydrogen, C 1-6 alkyl, —C(═O)(C 1-6 alkyl), benzyl, —CH 2 CONH 2 , —CHF 2 , —or —CF 3 —; and R 3 , R 4 , R 5 and R 6 are the same or different and independently hydrogen or C 1-6 alkyl.