Patent ID: 8076354

Claim:
A compound of formula (I): wherein represents a single or double bond, such that at least one bond within the 5 membered ring system is a double bond; Ring A may be optionally substituted by 1,2 or 3 R a groups; R 4 and R 5 independently represent hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl, C 1-6 alkanol, haloC 1-6 alkyl, —(CH 2 ) n —NR x R y , —(CH 2 ) s —COOR z , —(CH 2 ) n —O—(CH 2 ) m —OH, —(CH 2 ) n -aryl, —(CH 2 ) n —O-aryl, —(CH 2 ) n -heterocyclyl or —(CH 2 ) n —O-heterocyclyl wherein said C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl, aryl and heterocyclyl groups may be optionally substituted by 1, 2 or 3 R a groups; R x , R y and R z independently represent hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 alkanol, —COOC 1-6 alkyl, hydroxy, C 1-6 alkoxy, haloC 1-6 alkyl, —CO—(CH 2 ) n —C 1-6 alkoxy, C 1-6 alkylamino, C 3-8 cycloalkyl or C 3-8 cycloalkenyl; R 2 represents a —CONR 7 R 8 or —COR x group; R 7 and R 8 independently represent hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl, aryl, heterocyclyl or R 7 and R 8 together with the nitrogen atom to which they are attached may form a nitrogen containing heterocyclyl ring, wherein said C 1-6 alkyl, aryl and heterocyclyl may be optionally substituted by 1, 2 or 3 R b groups; R a represents halogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl, —OR x , —O—(CH 2 ) n —OR x , haloC 1-6 alkyl, haloC 1-6 alkoxy, C 1-6 alkanol, ═O, ═S, nitro, Si(R x ) 4 , —(CH 2 ) s —CN, —S—R x , —SO—R x , —SO 2 —R x , —COR x , —(CR x R y ) s —COOR z , —(CH 2 ) s —, CONR x R y , —(CH 2 ) s —NR x R y , —(CH 2 ) s —NR x COR y , —(CH 2 ) s—NR x SO 2 —R y , —(CH 2 ) s —NH—SO 2 —NR x R y , —OCONR x R y , —(CH 2 ) s —NR x CO 2 R y , —O—(CH 2 ) s —CR x R y —(CH 2 ) t —OR z or —(CH 2 ) s —SO 2 NR x R y groups; R b represents an R a group or a —Y-carbocyclic or —Z-heterocyclyl group wherein said carbocyclic and heterocyclyl groups may be optionally substituted by 1, 2 or 3 R a groups; Y and Z independently represent a bond, —CO—(CH 2 ) s —, —COO—, —(CH 2 ) n —, —NR x —(CH 2 ) s —, —(CH 2 ) s —NR x —, —CONR x —, —NR x CO—, —SO 2 NR x —, —NR x SO 2 —, —NR x CONR y —, —NR x CSNR y —, —O—(CH 2 ) s —, —(CH 2 ) s —O—, —S—, —SO— or —(CH 2 ) s —SO 2 —; m and n independently represent an integer from 1-4; s and t independently represent an integer from 0-4; or a pharmaceutically acceptable salt thereof.