Patent ID: 8101619

Claim:
A compound of formula (1), or a tautomer, a stereoisomer, or an N-oxide thereof, or a salt or hydrate of any of the foregoing, wherein: X is chosen from a sulphur atom and an oxygen atom; R 1 is chosen from a hydrogen atom, and (C 1 -C 6 )alkyl, CF 3 , CH 2 CF 3 , OH and O—(C 1 -C 6 )alkyl groups; R 2 is chosen from a hydrogen atom, a halogen, a cyano and a (C 1 -C 6 )alkyl group; R 3 is chosen from a hydrogen atom and a (C 1 -C 6 )alkyl group; R 4 is chosen from a hydrogen atom and a (C 1 -C 6 )alkyl group, wherein said (C 1 -C 6 )alkyl group is optionally substituted with a halogen atom; is chosen from: wherein the dot represents the point of attachment to the remaining portion of the compound of formula (1), wherein the compound of formula (1) exhibits serotonin reuptake inhibition and partial dopamine-D 2 receptor agonism, and wherein: the phenylpiperazine portion of formula (1) is chosen from: wherein the dot represents the point of attachment of said phenylpiperazine portion of formula (1) to