Patent ID: 7083646

Claim:
A surface modified medical device comprising: a medical device comprising a functional group-containing polymeric material that comprises monomeric units having functional groups; and a coating on a substantially entire surface of said medical device, said coating comprising one or more synthetic, reactive, hydrophilic polymers, wherein said hydrophilic polymers form direct covalent bonds with said functional groups of said functional group-containing polymeric material; wherein the functional group-containing polymeric material is selected from polymers comprising monomeric units selected from the group consisting of glyceryl methacrylate, 3-hydroxypropyl methacrylamide, acrylic acid, N-carboxy-β-alanine-N-vinyl ester, 2-isopropenyl-4, 4-dimethyl-2-oxazolin-5-one, 2-vinyl-4,4-dimethyl-2-oxazolin-5-one, spiro-4′-(2′-isopropenyl-2′-oxazolin-5-one)cyclohexane, spiro-4′-(2′-vinyl-2′-oxazolin-5′-one)cyclohexane, 2-(1-propenyl)-4,4-dimethyl-oxazolin-5-one, methacrylic anhydride, acrylic anhydride, maleic anhydride, glycidyl methacrylate, and combinations thereof; fluorocarbon polymers; polyesters; polyamides; polyurethanes; fluorine-containing polysiloxane elastomers; and combinations thereof.