Patent ID: 8361469

Claim:
A monoclonal antibody that is capable of binding the Kunitz 2 (K2) domain of tissue factor pathway inhibitor (TFPI), wherein the heavy chain of said antibody comprises: a CDR1 sequence of amino acids 31 to 35 (NYAMS) of SEQ ID NO: 18 and a CDR2 sequence of amino acids 50 to 66 (TISRSGSYSYFPDSVQG) of SEQ ID NO: 18 and a CDR3 sequence of amino acids 99 to 110 (LGGYDEGDAMDS) of SEQ ID NO: 18 and wherein the light chain of said antibody comprises: a CDR1 sequence of amino acids 24 to 39 (KSSQSLLESDGKTYLN) of SEQ ID NO: 15; and a CDR2 sequence of amino acids 55 to 61 (LVSILDS) of SEQ ID NO: 15; and a CDR3 sequence of amino acids 94 to 102 (LQATHFPQT) of SEQ ID NO: 15.