Patent ID: 8802678

Claim:
Compounds of the formula (I): wherein NR 1 R 2 is: Z is: R representing; cyanoalkyl; monohalogenocyanoalkyl; polyhalogenocyanoalkyl; hydroxyalkyl; monohalogenoalkyl; polyhalogenoalkyl; monhalogenocycloalkyl; polyhalogenocycloalkyl; cyanocycloalkyl; monohalogenoalkoxy; polyhalogenoalkoxy; alkoxyalkyl; monohalogeno-alkoxyalkyl; polyhalogenoalkoxyalkyl; alkoxyalkoxyalkyl; monohalogeno-alkoxyalkoxyalkyl; polyhalogenoalkoxyalkoxyalkyl; alkylcarbonyl; aryloxy; aryloxyalkyl; mono- or polyhalogenoaryloxyalkyl; arylalkoxy; alkenyl; cycloalkenyl; cycloalkenylalkyl; cycloalkenyl fused with benzene; alkynyl, dialkylaminoalkyl; halodialkylaminoalkyl; polyhalogenodialkylaminoalkyl; where is a non aromatic heterocycle selected from the group consisting of pyrrolidinyl, tetrahydrofuranyl, piperidyl, dihydropyranyl, and 2,3-dihydrofuranyl, optionally substituted with one or more moieties selected from the group consisting of acyl, alkyl and halogen; arylaminoalkyl; alkoxyalkylamino; alkoxy(alkyl)amino; cyanoalkylamino; alkylcarbonylalkyl; acylaminoalkyl; aminocarbonylalkyl; alkylsulfanylalkyl; alkylsulfinylalkyl; alkylsulfonylalkyl; n being an integer from 1 to 3; m being an integer from 0 to 4; Ar representing an aryl; an heteroaryl selected from the group consisting of pyridyl, pyrimidinyl, quinolinyl and benzothienyl or an aryl fused with a cycloalkyl or an heterocycle selected from the fused systems resulting from the condensation of a phenyl group with a dioxolanyl or a dioxanyl; Ar being optionally substituted with one or more alkyl; alkenyl; alkynyl; cyano; halogeno; alkoxy; monohalogenoalkoxy; polyhalogenoalkoxy; alkoxyalkyl; dialkylamino; alkylsulfanyl; alkylsulfinyl; alkylsulfonyl; monohalogenoalkylsulfanyl; monohalogenoalkylsulfinyl; monohalogenoalkylsulfonyl; polyhalogenoalkylsulfanyl; polyhalogenoalkylsulfinyl; polyhalogenoalkylsulfonyl; oxazolyl; aryl; aralkyl; aryloxy; alkoxy-carbonylamino; acyl; acylamino; aminocarbonyl; monoalkylaminocarbonyl; dialkylaminocarbonyl; alkylsulfonylamino; monohalogenoalkyl; polyhalogenoalkyl; hydroxyl; hydroxyalkyl; oxoalkyl; with the proviso that: when Z is NHCH and NR1R2 is with Ar representing a phenyl substituted with two chlorine atoms or fused with a carbocycle, then R is not alkenyl; or their pharmaceutically acceptable salts, or the polymorphic, crystalline structures of these compounds or their optical isomers, racemates, diastereomers or enantiomers.