Patent ID: 7414043

Claim:
A 9α-Substituted estra-1,3,5(10)-triene compound of formula I wherein R 3 is hydrogen or R 18 , R 18 is a straight-chain or branched-chain, saturated or unsaturated hydrocarbon radical with up to 6 carbon atoms, a trifluoromethyl group, an optionally substituted aryl, heteroaryl or aralkyl radical, an acyl radical COR 19 , or R 20 SO 2 , R 19 is an optionally substituted, straight-chain or branched-chain hydrocarbon radical with up to 10 carbon atoms that is saturated or unsaturated in up to three places and is optionally partially or completely halogenated, R 20 is R 21 R 22 N, R 21 and R 22 are, independently of one another, a hydrogen atom, a C 1 -C 5 -alkyl radical, or C(O)R 23 , R 23 is an optionally substituted, straight-chain or branched-chain hydrocarbon radical with up to 10 carbon atoms that is saturated or unsaturated in up to three places and is optionally partially or completely halogenated, an optionally substituted C 3 -C 7 -cycloalkyl radical, an optionally substituted C 4 -C 15 -cycloalkylalkyl radical or an optionally substituted aryl, heteroaryl or aralkyl radical, or, together with the N atom, a polymethylenimino radical with 4 to 6 C atoms or a morpholino radical, R 17 and R 17′ are, in each case independently of one another, a hydrogen atom or a halogen atom, R 9 is a straight-chain or branched-chain alkenyl or alkinyl radical with 2 to 6 carbon atoms, which is optionally partially or completely fluorinated, or an ethinyl or prop-1-inyl radical, R 13 is a methyl group or an ethyl group, R 16 is a hydroxy group or R 18 O—, R 20 SO 2 —O— or OC(O)R 23 , and R 17 and R 17′ are, in each case independently of one another, a hydrogen atom or a halogen Atom, or a pharmaceutically acceptable salt thereof.