Patent ID: 7157098

Claim:
A nebulized liposome:DNA aerosol suitable for delivery of said DNA to the respiratory tract of an individual upon inhalation of said aerosol, comprising: (a) one of a cationic lipid dipalmitoyl-sn-glycero-ethylphosphocholine (DPEP) or dilauroyl-sn-glycero-ethylphosphocholine (DLEP) and dioleoylphosphatidylethanolamine (DOPE); and (b) a plasmid cDNA sequence encoding a protein having tumor suppressor or pro-apoptotic activity; wherein said cationic lipid and said plasmid cDNA are present in the composition in a ratio of about 2:1 μg lipid: μg DNA to about 24:1 μg lipid: μg DNA.