Patent ID: 8618303

Claim:
A compound of formula I wherein R 1 is or is phenyl, pyridinyl or pyridazinyl, wherein phenyl, pyridinyl and pyridazinyl are each optionally substituted by cyano, lower alkyl, halogen-substituted phenyl, lower alkyl-substituted [1,2,4]oxadiazol-3-yl or by 2-oxo-piperidin-1-yl; X is NR or O; R is â€”C(O)-lower alkyl, â€”C(O)-cycloalkyl substituted by lower alkyl, cycloalkyl or is phenyl, pyridinyl or pyridazinyl, wherein phenyl, pyridinyl and pyridazinyl are each optionally substituted by lower alkyl, lower alkoxy, cyano, â€”C(O)-lower alkyl, halogen or lower alkyl substituted by halogen; R 2 is hydrogen or lower alkyl; R 3 is hydrogen, halogen, cyano, lower alkyl or lower alkyl substituted by halogen; R 4 is hydrogen or lower alkyl; wherein R 2 and R 4 are not simultaneously hydrogen or lower alkyl; R 5 is lower alkyl; and R 6 is halogen, hydroxy, lower alkyl, lower alkoxy, lower alkyl substituted by halogen, S(O) 2 -lower alkyl or cyano; or a pharmaceutically active salt, sterioisomer or racemic or non-racemic mixture thereof.