Patent ID: 8859545

Claim:
A compound having a formula 1: wherein A and B are independently selected from CR 2′ R 2′ , CO, and CS; Y is CR 2′ R 2′ ; W is N; Z is selected from O and NR 2 ; L is substituted or unsubstituted C 1 -C 9 alkylene or substituted or unsubstituted C 1 -C 9 heteroalkylene; R 1 is a substituted or unsubstituted carbocyclic group or a substituted or unsubstituted heterocyclic group; R 2 is selected from hydrogen, C 1 -C 6 alkyl, or C 3 -C 8 cycloalkyl; each R 2′ is independently selected from hydrogen, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, aryl and aralkyl; R 3 is a substituted or unsubstituted carbocyclic group or a substituted or unsubstituted heterocyclic group, provided that R 3 is other than substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl; and R 4′ is H; or a pharmaceutically acceptable salt, solvate, prodrug, stereoisomer, tautomer or isotopic variant thereof.