Patent ID: 8138005

Claim:
A method for fabricating a high-sensitivity field-effect transistor biosensor for diagnosing cancers, comprising: (a) adding a surfactant to a nonpolar solvent at −20° C. to 0° C.; (b) adding an aqueous solution of a metal salt and an oxidizing agent to the surfactant solution with stirring to form micelles having a cylinder shape; (c) adding conductive polymer monomers and functional monomers to be copolymerized to the micelles dropwise to prepare one-dimensional conductive polymer nanomaterials with controlled surface functional groups; (d) fixing the nanomaterials on an electrode substrate with a surface modified through chemical reaction; (e) adhering an anti-VEGF aptamer to the surface of the nanomaterials through chemical reaction to obtain a sensor medium; and (f) providing a detector to detect variations in electrical properties of the sensor medium using a field-effect transistor array through a liquid-ion gate.