Patent ID: 8658632

Claim:
A compound having the structure: wherein: R 1 is H, or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkenyl which is unsubstituted or substituted with at least one hydroxyl group; and R 2 is H, or a C 1 -C 3 alkyl or C 3 -C 6 cycloalkyl; or R 1 and R 2 form a C 3 -C 6 heterocyclic ring with the nitrogen bonded to said R 1 and R 2 ; wherein any carbon constituent of R 1 or R 2 can be replaced by O, S, or R′N wherein R′ is H or a C 1 -C 6 alkyl; R 3 is in which: R 4 is H, or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkenyl; R 5 is a C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 3 -C 6 cycloalkyl, or C 2 -C 6 alkyl ether which is unsubstituted or substituted with one or more of hydroxyl, phenyl, phenyloxy, or fluorine, or R 5 is NR 7 R 8 , or C(O)NR 7 R 8 in which R 7 and R 8 are independently selected from H, a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 cycloalkyl, or C 3 -C 6 cycloalkenyl group; R 6 is H, or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 cycloalkyl, or C 3 -C 6 cycloalkenyl group; wherein any carbon constituent of R 4 , R 5 , R 6 , R 7 or R 8 can be replaced by O, S, or R′N wherein R′ is H or a C 1 -C 6 alkyl; and n is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.