Patent ID: 7714008

Claim:
A compound having the formula I: or a pharmaceutically acceptable salt, stereoisomer, or C 1 -C 6 alkyl ester thereof or a tautomer or a pharmaceutically acceptable salt, stereoisomer, or C 1 -C 6 alkyl ester thereof; or a mixture thereof, wherein X is absent or is selected from H, (C 1 -C 6 )alkyl, Cl, Br, F, I, CN, NO 2 , perfluoro(C 1 -C 4 )alkyl, (C 1 -C 6 )alkoxy, perfluoro(C 1 -C 4 )alkoxy, or an optionally substituted aryl(C 1 -C 4 )alkoxy; Q is an optionally substituted (C 4 -C 8 )cycloalkyl, or an optionally substituted (C 5 -C 8 )cycloalkenyl; L 1 is a bond; P is an optionally substituted aromatic ring or an optionally substituted heteroaromatic ring; L 2 is a bond, (C 1 -C 6 )alkylene, (C 2 -C 6 )heteroalkylene, oxymethylene, O, S(O) k , N(R a ), C(O)N(R b ), SO 2 N(R b ), (C 1 -C 4 )alkylene-C(O)N(R b ), (C 1 -C 4 )alkylene-N(R b )C(O), (C 2 -C 4 )alkenylene-C(O)N(R b ), (C 2 -C 4 )alkenylene-N(R b )C(O), (C 1 -C 4 )alkylene-SO 2 N(R b ), (C 1 -C 4 )alkylene-N(R b )SO 2 , (C 2 -C 4 )alkenylene-SO 2 N(R b ), or (C 2 -C 4 )alkenylene-N(R b )SO 2 ; M is an optionally substituted phenyl; R a is H, (C 1 -C 6 )alkyl, aryl(C 1 -C 3 )alkyl, or (C 2 -C 6 )heteroalkyl; R b is H, (C 1 -C 6 )alkyl, or (C 2 -C 6 )heteroalkyl; R 1 , R 2 , R 3 , R 4 , and R 5 are independently selected from H, or (C 1 -C 6 )alkyl; the subscript k is, in each instance, independently selected from 0, 1, or 2; and the dashed line indicates that there is a single or double bond between the carbon atom bearing the R 1 and the carbon atom bearing the R 2 .