Patent ID: 8134004

Claim:
A compound of the formula (I): wherein ring A is wherein one of X 1 and X 3 is N, another of X 1 and X 3 is NH or S, and X 2 is N or CR 5 , one of X 1 and X 3 is CH 2 , another of X 1 and X 3 is NH or N, and X 2 is C═O or N, one of X 1 and X 3 is CR 6 , another of X 1 and X 3 is NH, and X 2 is N or CR 5 , X 1 and X 3 are NH and X 2 is C═O, or Y 1 is N or CR 7 , Y 2 is N or CR 8 , Y 3 is N or CR 9 and Y 4 is N or CR 10 ; the substitution site of ring B is the alpha- or beta-position; E is CH or N; G, J and K are each CH; F is CH or C—CH 3 ; L is N and T is CH; R 1 and R 2 are each independently hydrogen, (C 1 -C 6 )alkyl, or hydroxy(C 1 -C 6 )alkyl; R 3 is hydrogen; R 4 is (C 1 -C 6 )alkyl, hydroxy(C 1 -C 6 )alkyl, (C 3 -C 6 )cycloalkyl, (C 1 -C 4 )alkyl(C 3 -C 6 )cycloalkyl, (C 1 -C 4 )alkoxy(C 1 -C 6 )alkyl optionally substituted with halo or halo(C 2 -C 6 )alkyl optionally substituted with hydroxy, R 5 and R 6 are each independently hydrogen, (C 1 -C 6 )alkyl, hydroxy(C 1 -C 6 )alkyl or hydroxy(C 1 -C 6 )alkoxy-(C 1 -C 6 )alkyl; R 7 , R 8 , R 9 and R 10 are each independently hydrogen, halo, (C 1 -C 6 )alkyl, hydroxy(C 1 -C 6 )alkyl or hydroxy(C 1 -C 6 )alkoxy-(C 1 -C 6 )alkyl; and each dotted bond is a single or a double bond; or a pharmaceutically acceptable salt thereof.