Patent ID: 7335477

Claim:
An assay for detecting antibody to scrub typhus comprising: a) Obtaining a sample from a subject; and b) Exposing the sample to at least one polypeptide, selected from the group consisting of: an isolated polypeptide consisting of SEQ ID NO: 4, an isolated polypeptide consisting of SEQ ID NO: 5, or a combination thereof, said polypeptide or polypeptides being the refolded expressed product or products of truncated non-fusion r56 genes from Orientia tsutsugamushi; c) Incubating said sample, wherein said antibody binds said at least one polypeptide forming a complex; d) Binding a detectable label to said complex wherein a detectable signal is produced; e) Detecting the signal, wherein the signal indicates the presence of said antibody.