Patent ID: 7612065

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof; wherein Y is selected from —(CH 2 )-Q 1 ; —(CO)-Q 1 ; —(CO)NH-Q 1 ; —(CO)—O-Q 1 ; —(SO 2 )-Q 1 or —(SO 2 )NH-Q 1 ; Q 1 is a C 1 -C 6 straight chain or branched alkyl or alkenyl group; a 5-7 membered aromatic or non-aromatic heterocyclic ring; or a 9-14 membered bicyclic or tricyclic aromatic or non-aromatic carbocyclic or heterocyclic ring system, wherein said alkyl, alkenyl, ring or ring system is optionally substituted with one to four substituents, each of which is independently selected from NH 2 , NH—R, N(R) 2 , NO 2 , OH, OR, CF 3 , halo, CN, CO 2 H, C(O)—NH 2 , C(O)—NH—R, C(O)—N(R) 2 , C(O)—R, SR, S(O)—R, S(O) 2 —R, S(O) 2 —NH—R or —R; W is N; R 8 is a lone pair of electrons; A 1 is CR 1 ; A 2 is CR 2 ; A 3 is CR 3 ; A 4 is CR 4 ; R 1 is —NHR 5 , —OR 5 , —SR 5 , or —R 5 ; R 2 , R 3 , and R 4 are independently selected from —(CO)NH 2 , —(CO)NHR, —(CO)N(R) 2 , —NHR 5 , —NHCH 2 R 5 , —OR 5 , —SR 5 , —R 5 , —NH(CO)—R 6 , —NH(CO)—NHR 6 , —NH(CO)—NH(CO)R 6 , —NH(CO)—OR 6 , —NH(SO 2 )—R 6 , —NH(SO 2 )—NHR 6 , —C(O)OH, —C(O)OR, —(CO)-Q 1 , —(CO)NH-Q 1 , —(CO)NR-Q 1 , —(CO)—O-Q 1 , —(SO 2 )-Q 1 or —(SO 2 )NH-Q 1 ; R 5 and R 6 are each independently selected from H; N(R) 2 , NHOH, NO 2 , C(O)OR or halo; a C 1 -C 6 straight chain or branched alkyl, alkenyl or alkynyl group; a 5-7 membered aromatic or non-aromatic carbocyclic or heterocyclic ring; or a 9-14 membered bicyclic or tricyclic aromatic or non-aromatic carbocyclic or heterocyclic ring; wherein said alkyl, alkenyl, ring or ring system is optionally substituted with one to four substituents, each of which is independently selected from NH 2 , NHR, NHC(O)OR, N(R) 2 , NO 2 , OH, OR, CF 3 , halo, CN, Si(R) 3 , CO 2 H, COOR, CONH 2 , CONHR, CON(R) 2 , COR, SR, S(O)R, S(O) 2 R, S(O) 2 NHR or R; R is a C 1 -C 6 straight chain or branched alkyl or alkenyl group, a 5-7 membered aromatic or non-aromatic carbocyclic or heterocyclic ring, or a 9-10 membered bicyclic aromatic or non-aromatic carbocyclic or heterocyclic ring system.