Patent ID: 7928137

Claim:
A serine protease inhibitor compound of formula (I) where R 1 and R 2 each independently is hydrogen or hydroxyl, alkoxy, alkyl, aminoalkyl, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, acyloxymethoxycarbonyl or alkylamino optionally substituted by hydroxy, alkylamino, alkoxy, oxo, aryl or cycloalkyl; each R 3 independently is R 1 , R 2 , amino, halo, cyano, nitro, thiol, alkylthio, alkylsulphonyl, alkylsulphenyl, alkylsulphonamido, alkylaminosulphonyl, haloalkoxy and haloalkyl; X—X is —CONH—; L is an organic linker group containing 1 to 5 backbone atoms selected from C, N, O and S, or a branched alkyl or cyclic group; Y is a CR 1 group; Cy is an aryl group having 5 to 10 ring atoms including 1, 2, or 3 heteroatoms selected from O, N, or S, wherein Cy is optionally substituted by groups R 3 ; and Lp(D) n is a lipophilic organic group, selected from an alkyl, heterocyclic, alkenyl, alkaryl, cycloalkyl, polycycloalkyl, cycloalkenyl, aryl, aralkyl or haloalkyl group or a combination of two or more such groups optionally substituted by one or more of oxa, oxo, aza, thio, halo, amino, hydroxy or R 3 groups; or a physiologically tolerable salt thereof.