Patent ID: 8003795

Claim:
A compound of Formula III, stereoisomers thereof, tautomers thereof, solvates thereof, and pharmaceutically acceptable salts thereof; wherein R 1 and R 2 are independently —H, —CH 2 ) 0-6 COOR′, —C(O)R″, or a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, heterocyclyl, or heterocyclylalkyl group; or R 1 and R 2 together are a methylene group; R 3 and R 8 are independently —H, —OH, —Cl, —Br, —F, —I, —CN, —NH 2 , —C(O)NH 2 , —COOH, or a substituted or unsubstituted alkyl, alkenyl, alkoxy or aralkyl group; R 3 ′ is —H, or R 3 and R 3 ′ together are an oxo group; R 4 is —H, halogen, —OR′, —OSO 2 R″, —OC(O)R″, —OC(O)OR″, —OC(O)NR′R″, —O-alkylene-NR′R′, —O-alkylene-OSO 2 R″, —O-alkylene-S(O) 0-2 R″, —O-alkylene-NR′SO 2 R″, —O-alkylene-N(R′)C(O)R′, or a substituted or unsubstituted alkyl group; R 5 and R 6 are independently —H, halogen, —OH, or a substituted or unsubstituted alkoxy group; or R 4 and R 5 together are a methylenedioxy group, or R 5 and R 6 together are a methylenedioxy group; R 7 is —H, halogen, —OH, or a substituted or unsubstituted alkyl or alkoxy group; each R′ is independently a hydrogen, or a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, heterocyclyl, or heterocyclylalkyl group; each R″ is independently a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, heterocyclyl, or heterocyclylalkyl group; with the proviso that when R 4 is —H, —OH or a C 1-4 alkoxy group, then R 5 is not —H, —OH or a C 1-4 alkoxy group; and when R 1 and R 2 are both —CH 3 or when R 1 and R 2 together are a methylene group, then R 5 is not OH and R 4 and R 5 together are not a methylenedioxy group; and when R 4 is OC(O)R″, then R 5 is not OC(O)R″ or methoxy.