Patent ID: 8058299

Claim:
A compound of formula (I): wherein: R 1 is phenyl or 5- or 6-membered heteroaryl, said phenyl and heteroaryl being unsubstituted or substituted with halogen, lower alkyl, alkoxy or Oâ€”CF 3 ; R 2 is halogen, haloloweralkyl or alkoxy; R 3 is hydroxy, amine, lower alkyl amine, haloloweralkyl, lower alkoxy, lower alkenyloxy, cycloloweralkyl, unsubstituted or substituted with one to four substituents from lower alkyl, hydroxy, halogen, â€”C(O)OH, â€”C(O)O-lower alkyl or â€”C(O)O-lower alkyl-phenyl, 5- or 6-membered heterocycloalkyl, unsubstituted or substituted, with one to four substituents from lower alkyl, hydroxy, halogen, â€”SO 2 -loweralkyl, â€”C(O)OH, â€”C(O)O-lower alkyl or â€”C(O)O-lower alkyl-phenyl, 6-membered aryl, unsubstituted or substituted with one to four substituents from lower alkyl, hydroxy, halogen, â€”C(O)OH, â€”C(O)O-lower alkyl or â€”C(O)O-lower alkyl-phenyl, 5- or 6-membered heteroaryl, unsubstituted or substituted with one to four substituents from lower alkyl, hydroxy, halogen, â€”C(O)OH, C(O)O-lower alkyl or â€”C(O)O-lower alkyl-phenyl, (CH 2 ) n C(O)OH, CH 2 C(lower alkyl) 2 C(O)OH, CH 2 (cycloalkyl)C(O)OH, (cycloalkyl)C(O)OH, CH 2 C(CH 3 ) 3 , (CH 2 ) n -cycloalkyl, cycloalkenyl, bicycloalkenyl-C(O)OH, Oâ€”C(â•C)-lower alkyl, Oâ€”(CH 2 ) n -phenyl, NSO 2 -loweralkyl, NSO 2 -cycloalkyl, NSO 2 -aryl, N-lower alkyl, N-cycloalkyl, said cycloalkyl being unsubstituted or substituted with â€”C(O)OH, N-heterocycloalkyl, N-aryl, Nâ€”(CH 2 ) n -aryl, N-heteroaryl, said heteroaryl being unsubstituted or substituted with alkyl, Nâ€”CH(lower alkyl)C(O)OH, N-(cycloalkyl)C(O)OH, Nâ€”CH(lower alkyl)C(O)O-lower alkyl, or phenylâ€”C(O)OH; X is 6-membered aryl, said aryl being unsubstituted or substituted with lower alkyl, halogen or cyano; Y is 6-membered heterocycloalkyl, said heterocycloalkyl being unsubstituted or substituted with lower alkyl, halogen or cyano; and n is 1, 2 or 3, or pharmaceutically acceptable salts thereof.