Patent ID: 7601840

Claim:
A compound of Formula (I′): or a pharmaceutically acceptable salt, racemate or stereoisomer thereof, wherein, X is hydrogen; C 1 to C 6 alkyl optionally substituted with one or more halogen hydroxyl; halogen; or C 1 to C 5 alkoxy optionally substituted with phenyl; R 0 is halogen; cyano; nitro; sulfonyl substituted with C 1 to C 6 alkyl or morpholinyl; amino optionally substituted with C 1 to C 6 alkyl, —C(O)—R b , —C(O)O—R b , alkylsulfonyl, morpholinyl or tetrahydropyranyl; C 1 to C 6 alkyl optionally substituted with one or more substituents independently selected from hydroxyl, halogen or amino; —C(O)—R n ; or —OR a ; R a is hydrogen; C 2 to C 8 alkenyl; —C(O)O—R b ; —C(O)—NH—R b ; C 1 to C 8 alkyl optionally substituted with one or more substituents independently selected from hydroxyl, halogen, C 1 to C 4 alkoxy, C 1 to C 4 alkoxy-C 1 to C 4 alkoxy, amino, alkylamino, dialkylamino, acetamide, —C(O)—R b , —C(O)O—R b , aryl, morpholinyl, thiomorpholinyl, pyrrolidinyl, piperidinyl, piperazinyl, 1,3-dioxolan-2-one, oxiranyl, tetrahydrofuranyl, tetrahydropyranyl, 1,2,3-triazole, 1,2,4-triazole, furan, imidazole, isoxazole, isothiazole, oxazole, pyrazole, thiazole, thiophene or tetrazole; wherein amino is optionally substituted with C 1 to C 4 alkoxycarbonyl, imidazole, isothiazole, pyrazole, pyridine, pyrazine, pyrimidine, pyrrole, thiazole wherein pyridine and thiazole are each optionally substituted with C 1 to C 4 alkyl; wherein alkylamino and dialkylamino are each optionally substituted on alkyl with hydroxyl, C 1 to C 4 alkoxy, imidazole, pyrazole, pyrrole or tetrazole; and, wherein morpholinyl, thiomorpholinyl, pyrrolidinyl, piperidinyl, piperazinyl and oxiranyl are each optionally substituted with —C(O)—R n , —C(O)O—R n or C 1 to C 4 alkyl, wherein C 1 to C 4 alkyl is optionally substituted with hydroxyl; R b is hydroxyl; amino; alkylamino, optionally substituted on alkyl with hydroxyl, amino, alkylamino or C 1 to C 4 alkoxy C 1 to C 4 alkoxy; C 2 to C 8 alkenyl; C 2 to C 8 alkynyl; aryl optionally substituted with one or more substituents independently selected from halogen and C 1 to C 4 alkoxy; furan; or C 1 to C 8 alkyl optionally substituted with one or more substituents independently selected from C 1 to C 4 alkoxy, aryl, amino, morpholinyl, piperidinyl or piperazinyl; R d is phenyl substituted by one or more substituents independently selected from halogen, nitro, C 1 to C 6 alkyl, —C(O)O—R e , and —OR e ; R c is hydrogen; C 1 to C 6 alkyl optionally substituted with one or more substituents independently selected from halogen and alkoxy; or phenyl, wherein phenyl is optionally substituted with one or more substituents independently selected from halogen and alkoxy; and R d is hydroxyl, C 1 to C 4 alkoxy, amino or C 1 to C 6 alkyl.