Patent ID: 7592347

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt or thereof: wherein: R 1 represents aryl, heteroaryl, -aryl-X—C 3-7 cycloalkyl, -heteroaryl-X—C 3-7 cycloalkyl, -aryl-X-aryl, -aryl-X-heteroaryl, -aryl-X-heterocyclyl, -heteroaryl-X-heteroaryl, -heteroaryl-X-aryl or -heteroaryl-X-heterocyclyl; wherein said aryl, heteroaryl and heterocyclyl groups of R 1 may be optionally substituted by one or more substituents which may be the same or different, and which are selected from the group consisting of halogen, hydroxy, cyano, nitro, oxo, haloC 1-6 alkyl, polyhaloC 1-6 alkyl, haloC 1-6 alkoxy, polyhaloC 1-6 alkoxy, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylthio, C 1-6 alkoxyC 1-6 alkyl, C 3-7 cycloalkylC 1-6 alkoxy, —COC 1-6 alkyl, —COC 1-6 alkyl-halogen, —COC 1-6 alkyl-cyano, C 1-6 alkoxycarbonyl, C 1-6 alkylsulfonyl, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyloxy, C 1-6 alkylsulfonylC 1-6 alkyl, C 1-6 alkylsulfonamidoC 1-6 alkyl, C 1-6 alkylamidoC 1-6 alkyl, aryl, arylsulfonyl, arylsulfonyloxy, aryloxy, arylsulfonamido, arylcarboxamido, aroyl, NR 15 R 16 , —CONR 15 R 16 , —NR 15 COR 16 , —C(R 15 )═NOR 16 , —NR 15 SO 2 R 16 and —SO 2 NR 15 R 16 , wherein R 15 and R 16 independently represent hydrogen or C 1-6 alkyl or together form a heterocyclic ring; X represents a bond, O, CO, SO 2 , OCH 2 or CH 2 O; each R 2 and R 4 independently represents C 1-4 alkyl; R 3 represents C 3-8 alkyl, C 3-6 alkenyl, C 3-6 alkynyl, C 3-6 cycloalkyl, C 5-6 cycloalkenyl or —C 1-4 alkyl-C 3-6 cycloalkyl; wherein said C 3-6 cycloalkyl groups of R 3 may be optionally substituted by one or more substituents which may be the same or different, and which are selected from the group consisting of halogen, C 1-4 alkyl and trifluoromethyl; m and n independently represent 0, 1 or 2; p and q independently represent 1.