Patent ID: 7420059

Claim:
A compound having the structure wherein is a 5- or 6-membered fully saturated ring which includes one nitrogen atom which is separated from the N atom of the pyridine ring by a fusion carbon 2, and wherein A is n is 0 or 1; is —CR 6 R 7 —CR 6a R 7a —, or —CR 6 ═CR 7 —; R 1 is aryl; R 2 is alkyl or cycloalkyl; R 3 is selected from H, alkyl, C(O)R 8 , or SO 2 R 8 ; R 4 and R 5 are the same or different are independently selected from H or lower alkyl; R 6 , R 7 , R 6a and R 7a are the same or different are independently selected from H or lower alkyl; R 8 is selected from H, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or heterocyclo (wherein the attachment atom in the heterocyclo group is a carbon); and including a pharmaceutically acceptable salt thereof where R 5 is H, ester thereof, prodrug ester thereof, and all stereoisomers thereof.