Patent ID: 7691857

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: A is CH or nitrogen; B is —CH 2 —, —CHF—, —CF 2 —, NR 4 or O, with the proviso that when A is N, B is —CH 2 —, —CHF— or —CF 2 —; G is oxygen, R 1 is hydrogen or C 1-6 alkyl; R 2 is C 1-8 alkyl, —CH 2 -aryl, —CH 2 -heterocycle, —CH 2 -substituted C 5 cycloalkyl or a —CH 2 -substituted hetero cycle, each of which may be optionally substituted with one or more of halo, hydroxyl, C 1-6 alkyl, C 1-6 haloalky, C 1-8 alkoxy, C 1-6 haloalkoxy, C 2-6 alkenyl, C 2-6 haloalkenyl, C 2-6 alkynyl or C 2-6 haloalkynyl; R 3 is hydrogen; cyclobutyl, cyclopropyl, methyl, ethyl, isopropyl, butyl, secbutyl; R 5 is a 5-membered unsaturated heterocyclic ring having one of the following structures: R 6 is methyl, aralkyl, arylamino, aralkyl substituted by one or more halo and having a methylene group linking the aryl to the unsaturated 5-membered ring, aralkyl substituted by one or more halo and having an ethylene group linking the aryl to the unsaturated 5-membered ring; or R 5 may also be C 2 -C 4 -aralkyl, —CH 2 —O—R 7 where R 7 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 2 -C 4 aralkyl which groups may be optionally substituted with fluoro or hydroxy; and R 8 is hydrogen phenyl or halo-substituted phenyl; with the proviso that when either R 3 or R 8 is not hydrogen, the other is hydrogen.