Patent ID: 8361490

Claim:
A method for treating bladder cancer, comprising steps of: a. forming a drug carrier solution by incorporating into a hydrogel based biocompatible matrix each of the following components: i. a hydrogel-based biocompatible elastic adhesion substance comprising an agent adapted to increase adherence of a treatment solution to an internal wall of the bladder, said adhesion substance adapted to conform to anatomical morphology of said internal wall; ii. at least one treatment solution comprising (i) at least one drug carrier polymeric material selected from the group consisting of polvinylpyrrolidone (PVP) with water as a solvent, polyethylene glycol (PEG) with water as a solvent, and any combination thereof; and (ii) a cancer-fighting drug; iii. a buffering polymer for controlling concentration of said cancer-fighting drug reaching said internal wall of said bladder, said buffering polymer selected from the group consisting of polyurethanes, polyethylene terephthalate, polyactones, polycaprolactone, polyacrylonitrile, polyethylene glycol and any combination thereof; and, iv. a blocking polymer for controlling the concentration of said cancer-fighting drug reaching said inner volume of said bladder; said blocking polymer selected from the group consisting of polyvinylchloride, polyurethanes, polyanhydride, polyethylene glycol and any combination thereof; b. coating at least a part of said bladder with said drug carrier solution by directly and homogeneously contacting said drug carrier solution with the lining of at least a portion of said internal wall of said bladder, such that said drug carrier solution conforms to the anatomical morphology of at least a portion of said internal wall of said bladder; c. actively curing at least a portion of said drug carrier solution by use of at least one curing element selected from the group consisting of light, pressure, heat, a curing agent, and any combination thereof, thereby solidifying said portion of said drug carrier solution containing said cancer-fighting drug such that said solid drug carrier coating adheres to at least a part of said internal wall of said bladder; and, d. controlling (i) said concentration of said cancer-fighting drug reaching said internal wall of said bladder by means of said buffering solution; and, (ii) said concentration of said cancer-fighting drug reaching said inner volume of said bladder by means of said blocking polymer such that said cancer-fighting drug does not depart from said inner volume of said bladder with urine; thereby treating bladder cancer.