Patent ID: 7112593

Claim:
A compound (I) represented by the formula: wherein R 1 represents an optionally substituted vinyl group or an aromatic ring which may be substituted; n is an integer of 0 to 2; X, Y, and Z are the same as or different from each other and each represents an optionally substituted carbon atom, or an optionally substituted nitrogen atom; CyA represents pyrrolidine or piperidine; W represents a chain expressed by (1) optionally substituted —CH 2 —CH 2 —, (2) optionally substituted —CH═CH—, (3) —C≡C—, (4) an optionally substituted phenylene group, (5) a single bond, (6) —NH—CO—, (7) —CO—NH—, (8) —NH—CH 2 —, (9) —CH 2 —NH—, (10) —CH 2 —CO—, (11) —CO—CH 2 —, (12) —O—(CH 2 ) m, —, (13) —(CH 2 ) m —O—, wherein (m represents an integer of 0 to 5, (14) —O—CH 2 —CR 2 ═, (15) —O—CH 2 —CHR 2 —, wherein R 2 represents a hydrogen atom, a C 1-6 alkyl group, or a halogen atom, (16) —NH—S(O) 1 —, (17) —S(O) 1 —NH—, (18) —CH 2 —S(O) 1 — or (19) —S(O) 1 —CH 2 —, wherein 1 represents 0, 1, or 2; and A represents a group having any of the following structural formulae: wherein R 3 and R 4 are independent of each other and each represents a hydrogen atom or an optionally substituted C 1-6 alkyl group; R 5 and R 6 are independent of each other and each represents a hydrogen atom or an optionally substituted C 1-6 alkyl group; R 7 represents a hydrogen atom, an optionally substituted C 1-6 alkyl group, a hydroxyl group, an alkoxy group, a halogen atom or an optionally substituted amino group; R 8 represents a hydrogen atom, a hydroxyl group, an alkoxy group, a halogen atom or an optionally substituted amino group, B 1 represents an optionally substituted carbon atom, or an optionally substituted nitrogen atom; B 2 represents an optionally substituted carbon atom or nitrogen atom; a and b represent an integer of 0 to 4, provided that a+b is an integer of 0 to 4, c represents 0 or 1; and represents a single bond or a double bond, provided that when c is 1 in which A is a quinuclidine having R 8 represented by the case where R 8 is a hydrogen atom or a hydroxyl group; Arl is an aromatic heterocycle selected from the group consisting of pyridine, pyrimidine, pyrazine, pyridazine and triazine thereof; and W is one of(1) to (3), (6) to (11) and (16) to (19) are excluded, a salt thereof or a hydrate thereof.