Patent ID: 8236762

Claim:
A compound according to Formula (IA): A-B-C-E (IA) wherein: A is camptothecin or a derivative thereof; B is, rvAhp, rvAla, rvAnc, rvApn, rvArg, rvAsp, rvCha, rvDap(Z), rvGlu, or rvPhe; C is D 1 -D 2 -D 3 -D 4 wherein D 1 is glutaryl, succinyl, or deleted, D 2 is (Doc) m wherein m is, independently for each occurrence thereof, 4, 5 or 6 or [Peg]x, wherein x is, independently for each occurrence thereof, 0-100; D 3 is (Aepa) n wherein n is, independently for each occurrence thereof, 0 or 1; and D 4 is D-Phe or Lys-D-Tyr-D-Tyr; E is a somatostatin analog of the formula c (Cys-A 2 -A 3 -D-Trp-Lys-A 6 -Cys)-A 8 -R wherein A 2 is Phe or deleted; A 3 is Phe, 3-(I)Tyr or Tyr, A 6 is Abu, Thr or deleted; A 8 is Thr or deleted; and R is NH 2 or OH; or a pharmaceutically acceptable salt thereof.