Patent ID: 7050911

Claim:
A method of identifying differences between biopolymers, the method comprising the steps: a) providing at least one pair of different sets of labeled detector molecules wherein the different sets of labeled detector molecules of one pair are specifically bondable to a certain region in said biopolymers; and the labels of the one set of labeled detector molecules of said one pair differs from the labels of another one set of labeled detector molecules of said one pair; b) exposing said labeled detector molecules to said biopolymers under conditions permitting bonding reactions to occur between said labeled detector molecules and said biopolymers; wherein said one set of labeled detector molecules of said one pair binds to a certain region of the biopolymer overlapping with the certain region bound by said another one set of labeled detector molecules of said one pair; c) recording the presence, intensity and intensity ratios of the labeled detector molecules at selected regions of said biopolymers by scanning the biopolymers in longitudinal direction using a scanning device; d) evaluating the recorded intensities and intensity ratios, whereby the biopolymer is divided into a number of sections and by means of an appropriate calculation program, a false color is assigned to each of these sections based on the relative intensity ratios; and e) identifying differences between said biopolymers by comparing the result to that obtained for a different biopolymer, wherein the bonded labeled detector molecules of one set display a continuously changing label-signal intensity along the longitudinal direction of the biopolymer.