Patent ID: 8212011

Claim:
Compounds according to the formula: wherein R 1 is an amido which is NR′COR″, and R′ is hydrogen and R″ is aryl or heterocycle; wherein R 2 is hydrogen, hydroxy, or —R 8 —OR 9 , wherein R 8 is a covalent bond or alkyl, and R 9 is C-amido or acyl; or R 2 together with R 3 and the atoms to which they are attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein R 3 is hydrogen, hydroxy, or —R 10 —O—R 11 , wherein R 10 is a covalent bond or alkyl, and R 11 is C-amido or acyl; or R 3 together with R 2 and the atoms to which they are attached form a heterocyclic ring having 4 to 8 ring members with at least one heteroatom selected from oxygen or nitrogen; wherein R 4 is hydrogen, hydroxy, alkyl, carboxyl, —R 12 —O—R 13 , or —R 12 -R 14 , and wherein R 12 is a covalent bond or alkyl, and R 13 is C-amido or acyl, and R 14 is N-amido, —POR 15 R 16 , —SO 2 R 17 , or sulfonamido and wherein R 15 , R 16 , R 17 are independently alkoxy; wherein R 5 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or aralkyl; wherein R 6 is hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, alkoxy, aryloxy, or aralkoxy; wherein X 1 is —O—, —CO—, or —N—; wherein X 2 is —O—, —N—, —CR 19 — or —CO—, wherein R 19 is hydrogen, alkyl, alkenyl, alkynyl; wherein X 4 is —CR 20 —, wherein R 20 is hydrogen, alkyl, alkenyl, or alkynyl; wherein X 5 is —CR 21 , wherein R 21 is hydrogen, alky, alkenyl, alkynyl, or alkoxy; wherein X 6 , is —CR 22 wherein R 22 is hydrogen, alkyl, alkenyl, alkynyl, alkoxy, aryl, aralkyl, halogen, or nitro; wherein X 8 , is —CR 23 , wherein R 23 is hydrogen, alkyl, alkenyl, alkynyl, aryl, alkoxy; wherein X 9 is alkyl, alkenyl, alkynyl, ether, secondary or tertiary amino, or sulfanyl; wherein n is 0, 1, 2, or 3.