Patent ID: 7432089

Claim:
A process for the biological production of vitamin B6 which comprises cultivating a host cell transformed or transfected by an isolated DNA or by a vector or plasmid comprising the isolated DNA under conditions conducive to the production of vitamin B6, and recovering vitamin B6 from the culture, wherein the host cell is selected from Sinorhizobium or Escherichia and wherein the isolated DNA comprises a nucleotide sequence encoding PdxR, which is a flavin adenine dinucleotide-dependent D-erythronate 4-phosphate dehydrogenase, selected from the group consisting of: (a) a DNA sequence of SEQ ID NO:1; (b) a DNA sequence encoding a polypeptide which is at least 95% identical to SEQ ID NO: 2, and encodes a polypeptide having the activity of flavin adenine dinucleotide-dependent D-erythronate 4-phosphate dehydrogenase; and (c) a DNA sequence encoding a polypeptide which comprises the amino acid sequence of SEQ ID NO: 2, and encodes a polypeptide having the activity of flavin adenine dinucleotide-dependent D-erythronate 4-phosphate dehydrogenase.