Patent ID: 7671080

Claim:
A 1-benzylindole-2-carboxamide compound of formula I, wherein R 1 is H or F; R 2 is H, halogen, C 1-4 alkyl, C 1-4 alkyloxy, C 3-6 cycloalkyl or C 3-6 cycloalkylC 1-2 alkyl, said C 1-4 alkyl and C 1-4 alkyloxy being optionally substituted with one to three halogens or R 2 is a five or six membered heteroaryl ring comprising one or two heteroatoms selected from N and O or R 2 is a five or six membered saturated heterocyclic ring comprising one or two heteroatomic moieties selected from O and NR 8 ; R 3 is H or F; R 4 is H, halogen, CH 3 , OCH 3 or CF 3 or together with R 5 and the phenyl ring R 4 forms an indol-4-yl or a quinolin-5-yl; R 5 is H, halogen, C 1-4 alkyl, CF 3 , C 1-4 alkyloxy, OCF 3 or together with R 4 and the phenyl ring R 5 forms an indol-4-yl or a quinolin-5-yl; provided that one to three of R 1 -R 5 are not H; R 6 is one or two substituents selected from Cl, Br and CN; R 7 is C 1-6 alkyl optionally substituted with one to three halogens, C 3-6 cycloalkyl or C 3-6 cycloalkylC 1-2 alkyl each being substituted with 1-2 substituents selected from hydroxy, hydroxyC 1-2 alkyl, C 1-4 alkyloxy and C 1-2 thioalkyloxy, or R 7 is C 4-6 oxacycloalkylC 1-2 alkyl, said C 1-2 alkyl being optionally substituted with hydroxy or hydroxyC 1-2 alkyl or R 7 is C 4-6 oxacycloalkyl and R 8 is H, C 1-4 alkyl or C 1-4 acyl or a pharmaceutically acceptable salt thereof.