Patent ID: 7604811

Claim:
A method for inducing an immune response in mammals comprising administering a pharmaceutical composition comprising an antigenic synthetic peptide containing CFA/I pilus protein T-cell epitopes encapsulated within a biodegradable polymeric matrix comprising poly (DL-lactide-co-glycolide) having a relative ratio between the amount of lactide and glycolide components within the range of 48:52 to 58:42, wherein the CFA-I pilus protein T-cell epitopes consist of the amino acid sequence: (SEQ ID NO: 1) [4] (Asn-Ile-Thr-Val-Thr-Ala-Ser-Val-Asp-Pro), (SEQ ID NO: 11) (Gly-Asn-Tyr-Ser-Gly-Val-Val-Ser-Leu-Val), and mixtures thereof.