Patent ID: 6982258

Claim:
A compound of Formula I, and pharmaceutically acceptable salts, hydrates, solvates, and prodrugs thereof: wherein R 1 and R 2 are independently selected from the group consisting of OH, OC 1-6 alkyl, and halo; R 3 is C 1-6 alkyl; R 4 is selected from the group consisting of H, C 1-6 alkyl, aryl and heteroaryl, with C 1-6 alkyl being unsubstituted or substituted with 1-4 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, halo, NH 2 , NHC 1-4 alkyl and N(C 1-4 alkyl)(C 1-4 alkyl), and with aryl and heteroaryl being unsubstituted or substituted with 1-5 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, CF 3 , OCF 3 , halo, SH, SC 1-4 alkyl, NH 2 , NHC 1-4 alkyl, N(C 1-4 alkyl)(C 1-4 alkyl), CN, C(O)OH, C(O)OC 1-4 alkyl, C(O)NHC 1-4 alkyl, NHC(O)C 1-4 alkyl, OC(O)C 1-4 alkyl, SOC 1-4 alkyl, SO 2 C 1-4 alkyl, SO 2 NHC 1-4 alkyl and SO 2 NH 2 ; R 5 is selected from the group consisting of C 1-6 alkyl, cyclo(C 3 -C 6 )alkyl, aryl and heteroaryl, aryl-C 1-6 alkyl and heteroaryl-C 1-6 alkyl, with C 1-6 alkyl being unsubstituted or substituted with 1-4 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, halo, NH 2 , NHC 1-4 alkyl and N(C 1-4 alkyl)(C 1-4 alkyl), and with cyclo(C 3 -C 6 )alkyl, aryl, heteroaryl, aryl-C 1-6 alkyl and heteroaryl-C 1-6 alkyl, being unsubstituted or substituted with 1-5 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, CF 3 , OCF 3 , halo, SH, SC 1-4 alkyl, NH 2 , NHC 1-4 alkyl, N(C 1-4 alkyl)(C 1-4 alkyl), CN, C(O))OH, C(O)OC 1-4 alkyl, C(O)NHC 1-4 alkyl, NHC(O)C 1-4 alkyl, OC(O)C 1-4 alkyl, SOC 1-4 alkyl, SO 2 C 1-4 alkyl, SO 2 NHC 1-4 alkyl and SO 2 NH 2 ; and R 6 are either both H or together from ═CH 2 .