Patent ID: 8461128

Claim:
A compound of the formula: wherein A-B is —(R A ) 2 C—C(R B ) 2 — or —R A C═CR B —, wherein each occurrence of R A and R B is independently hydrogen, halogen, cyano, azido, hydroxyl, sulfhydryl, alkoxy, amino, alkylamino, dialkylamino; cyclic or acyclic, unsubstituted or substituted, branched or unbranched, aliphatic; cyclic or acyclic, unsubstituted or substituted, branched or unbranched heteroaliphatic; substituted or unsubstituted, branched or unbranched acyl; substituted or unsubstituted, branched or unbranched aryl; substituted or unsubstituted, branched or unbranched heteroaryl; L is of the formula: Y is selected from the group consisting of hydrogen; halogen; cyclic or acyclic, substituted or unsubstituted, branched or unbranched aliphatic; cyclic or acyclic, substituted or unsubstituted, branched or unbranched heteroaliphatic; substituted or unsubstituted, branched or unbranched acyl; substituted or unsubstituted, branched or unbranched aryl; substituted or unsubstituted, branched or unbranched heteroaryl; —OR Y ; —C(═O)R Y ; —CO 2 R Y ; —CN; —SCN; —SR Y ; —SOR Y ; —SO 2 R Y ; —NO 2 ; —N 3 ; —N(R Y ) 2 ; —NHC(═O)R Y ; —NR Y C(═O)N(R Y ) 2 ; —OC(═O)OR Y ; —OC(═O)R Y ; —OC(═O)N(R Y ) 2 ; —NR Y C(═O)OR Y ; or —C(R Y ) 3 ; wherein each occurrence of R Y is independently a hydrogen; a protecting group; halogen; cyclic or acyclic, substituted or unsubstituted, branched or unbranched aliphatic; cyclic or acyclic, substituted or unsubstituted, branched or unbranched heteroaliphatic; substituted or unsubstituted, branched or unbranched acyl; substituted or unsubstituted, branched or unbranched aryl; substituted or unsubstituted, branched or unbranched heteroaryl; an acyl moiety; alkoxy; aryloxy; alkylthio; arylthio; amino, alkylamino, dialkylamino, heteroaryloxy; or heteroarylthio moiety, and pharmaceutically acceptable salts thereof; wherein when a group is substituted, the group is substituted independently with at least one moiety selected from the group consisting of aliphatic, heteroaliphatic, aryl, heteroaryl, arylalkyl, heteroarylalkyl, alkoxy, aryloxy, heteroalkoxy, heteroaryloxy, alkylthio, arylthio, heteroalkylthio, heteroarylthio, F, Cl, Br, I, —OH, —SH, —NH 2 , —NO 2 , —CN, —CF 3 , —CH 2 CF 3 , —CHCl 2 , —CH 2 OH, —CH 2 CH 2 OH, —CH 2 NH 2 , —CH 2 SO 2 CH 3 , —C(O)R X , —CO 2 (R X ), —CON(R X ) 2 , —OC(O)R X , —OCO 2 R X , —OCON(R X ) 2 , —OR X , —SR X , —N(R X ) 2 , —S(O) 2 R X , and —NR X (CO)R X , wherein each occurrence of R X is independently hydrogen, aliphatic, heteroaliphatic, aryl, heteroaryl, arylalkyl, or heteroarylalkyl.