Patent ID: 7632805

Claim:
A method of binding a platelet derived growth factor in a subject having a condition associated with said platelet derived growth factor, comprising administering to the subject an effective amount of a growth factor binding compound of the general structure: or a pharmaceutically acceptable salt thereof, wherein R is n-butyl, n-propyl, benzyl, (C 1 -C 12 ) alkyl, (C 7 -C 18 ) aralkyl, (C 6 -C 18 ) aryl, (C 1 -C 12 ) alkenyl, (C 7 -C 18 ) aralkenyl, or (C 1 -C 12 ) alkylether, and X are independently cyclic peptide loops of the general structure: wherein R 1 , R 2 , R 3 , and R 4 are each amino acid side chains that define a tetrapeptide, wherein said tetrapeptide is covalently attached at the amino and carboxy termini of said tetrapeptide to a 3-aminomethyl-5-aminobenzarnide linking group, and wherein said tetrapeptide is GDAD (SEQ ID NO. 5), GDGY (SEQ ID NO. 6), GDDG (SEQ ID NO. 13), or GDDY (SEQ ID NO. 14).