Patent ID: 7582630

Claim:
A compound of Formula (I): or a salt thereof, wherein D is N; R 1 is phenyl, where said phenyl may be optionally substituted one or more times with C 1 -C 6 alkyl, C 1 -C 6 alkoxy, halogen, or C 1 -C 6 haloalkyl, a is 1 or 2; y is 0, 1, or 2; R 2 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 1 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 3 -C 7 cycloalkyl, halogen, tetrahydrofuranyl, pyranyl, 1,4-dioxanyl, 1,3-dioxanyl, piperidinyl, pyrrolidinyl, morpholinyl, tetrahydrothiopyranyl, tetrahydrothiophenyl, aryl, furanyl, thiophenyl, pyrrolyl, imidazolyl, pyrazolyl, triazolyl, tetrazolyl, thiazolyl, oxazolyl, isoxazolyl, oxadiazolyl, thiadiazolyl, isothiazolyl, pyridinyl, pyrazinyl, pyrimidinyl, quinolinyl, isoquinolinyl, benzofuranyl, benzothiophenyl, indolyl, indazolyl, cyano, azido, nitro, —OR 8 , —OR 6 R 8 , —R 6 R 7 , —R 6 R″, S(O) y R 7 , —C(O)R 7 , —C(O)OR 7 ,—C(O)NR 4 R 5 , —NR′(C═NR 4 )NR 4 R 5 , —OC(O)NR 4 R 5 , —OC(O)OR 7 , —C(═NR 4 )NR 4 R 5 , —NR 4 R 5 , —OC(O)R 7 , or —NR 7 C(O)R 7 ; R 3 is -(Q) p -(Q 1 ) where Q is O, N(R 8 ) or S(O) y , p is 0 or 1, y is 0, 1, or 2, and Q 1 is C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 1 -C 6 haloalkyl, aryl, aryl substituted with —C(O)N(H)R 6 NR 4 R 5 or —OC(H)(OH)R 6 NR 4 R 5 , furanyl, thiophenyl, pyrrolyl, imidazolyl, pyrazolyl, triazolyl, tetrazolyl, thiazolyl, oxazolyl, isoxazolyl, oxadiazolyl, thiadiazolyl, isothiazolyl, pyridinyl, pyridazinyl, pyrazinyl, pyrimidinyl, quinolinyl, isoquinolinyl, benzofuranyl, benzothiophenyl, indolyl, indazolyl, aralkyl, or —R 6 NR 4 R 5 ; R 4 and R 5 are independently hydrogen, C 1 -C 3 alkyl, C 3 -C 7 cycloalkyl, or R 4 and R 5 together with the nitrogen atom to which they are bound form piperidinyl, pyrrolidinyl, morpholinyl, or tetrahydrothiophenyl; R 6 is alkylene, arylene, furan-2,5-diyl, thiophene-2,4-diyl, 1,3,4-oxadiazole-2,5-diyl, 1,3,4-thiadiazole-2,5-diyl, 1,3-thiazole-2,4-diyl, 1,3,4-thiazole-2,5-diyl, pyridine-2,4-diyl, pyridine-2,3-diyl, pyridine-2,5-diyl, pyrimidine-2,4-diyl, quinoline-2,3-diyl, cycloalkylene, alkenylene, cycloalkenylene, or alkynylene; R 7 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 1 -C 6 alkynyl, —NR 4 R 5 , aryl, aralkyl, heteroaryl, cycloalkyl, heterocyclyl, —S(O) y R 8 , —C(O)R 8 , —C(O)OR 8 , —C(O)NR 4 R 5 , —S(O) 2 NR 4 R 5 , —NR′(C═NR 4 )NR 4 R 5 , —OC(O)NR 4 R 5 , —OC(O)OR 8 , —C(═NR 4 )NR 4 R 5 , —NR 4 R 5 , or —NR 7 C(O)R 7 R 8 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 1 -C 6 alkynyl, —NR 4 R 5 , aryl, aralkyl, heteroaryl, cycloalkyl, tetrahydrofuranyl, pyranyl, 1,4-dioxanyl, 1,3-dioxanyl, piperidinyl, pyrrolidinyl, morpholinyl, tetrahydrothiopyranyl, tetrahydrothiophenyl, or —S(O) 2 R 9 ; R 9 is C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; R′ is C 1 -C 3 alkylene; and R″ is —OR 7 , —OC(O)NR 4 R 5 , —OC(O)OR 7 , —OC(O)R 7 .