Patent ID: 8450284

Claim:
A lipopeptide building block comprising a lipid moiety and a coiled-coil peptide domain comprising three to eight heptad motifs: wherein, i) the said coiled-coil peptide domain comprises between 21 and 80 amino acid residues, ii) the said coiled-coil peptide domain is linked covalently to the lipid moiety, optionally via a linker, iii) each heptad motif is denoted by amino acid residues ‘abcdefg’, wherein the amino acid residues at positions ‘a’ and ‘d’ are selected from the group consisting of A, I, L, M, V, F, Y and W; and amino acid residues at positions ‘b, c, e, f and g’ in each heptad motif comprises no proline, and iv) the lipopeptide is optionally linked to an antigen.