Patent ID: 7781469

Claim:
A compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: Y is a group of the formula: wherein R 5 , R 6 , R 7 and R 8 are each independently hydrogen, halogen, hydroxy, cyano, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted lower alkoxy, optionally substituted lower alkylthio, optionally substituted acyl, optionally substituted amino, optionally substituted aryl, optionally substituted aryloxy, optionally substituted arylthio or optionally substituted heterocycle, R 9 and R 10 are each independently hydrogen, halogen, cyano, optionally substituted lower alkyl, optionally substituted lower alkoxy, optionally substituted amino or optionally substituted aryl, X 3 is COOR 17 or C(═NR 17 )NR 18 OR 19 , wherein R 17 , R 18 and R 19 are each independently hydrogen or optionally substituted lower alkyl, R 1 is optionally substituted aryl or optionally substituted heterocycle, R 2 is optionally substituted lower alkyl, R 3 and R 4 are each independently hydrogen, halogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted aryl or optionally substituted heterocycle, and X 1 is O, S or —ON═CR 14 - wherein R 14 is hydrogen or optionally substituted lower alkyl.