Patent ID: 8614324

Claim:
A compound or its pharmaceutically acceptable salt, wherein said compound corresponds in structure to Formula II wherein D and F are the same and are CH 2 , circle A is an aromatic or heteroaromatic ring system containing one ring or two fused rings; W is O; X is —S(O) 2 —; R 1 represents up to three substituent groups that themselves are the same or different, R 1a , R 1b , and R 1c , wherein each of those three groups, R 1a-c , is separately selected from the group consisting of H, C 1 -C 6 hydrocarbyl, C 1 -C 6 hydrocarbyloxy, C 1 -C 6 hydrocarbyl-oxycarbonyl, trifluoromethyl, trifluoromethoxy, C 1 -C 7 hydrocarboyl, hydroxy-, trifluoromethyl- or halogen-substituted C 1 -C 7 hydrocarboyl, C 1 -C 6 hydrocarbylsulfonyl, C 1 -C 6 hydrocarbyloxysulfonyl, halogen, nitro, phenyl, cyano, carboxyl, C 1 -C 7 hydrocarbyl carboxylate, carboxamide or sulfonamide wherein the amido nitrogen in either group has the formula NR 3 R 4 wherein R 3 and R 4 are the same or different and are H, C 1 -C 4 hydrocarbyl, or R 3 and R 4 together with the depicted nitrogen form a 5-7-membered ring that optionally contains 1 or 2 additional hetero atoms that independently are nitrogen, oxygen or sulfur, MAr, where M is —CH 2 —, —O— or —N═N— and Ar is a single-ringed aryl or heteroaryl group, and NR 5 R 6 wherein R 5 and R 6 are the same or different and are H, C 1 -C 4 hydrocarbyl, C 1 -C 4 acyl, C 1 -C 4 hydrocarbylsulfonyl, or R 5 and R 6 together with the depicted nitrogen form a 5-7-membered ring that optionally contains 1 or 2 additional hetero atoms that independently are nitrogen, oxygen or sulfur; and R 2 is C 1 -C 6 hydrocarbyl.