Patent ID: 8609394

Claim:
A recombinant microorganism producing chondroitin, defined as a linear glycosaminoglycan constituted by alternating residues of D-glucuronic acid (GlcUA) and N-acetyl-D-galactosamine (GalNAc) bound by β1-3 (GlcUA→GalNAc) and β1-4 (GalNAc→GlcUA) bonds, characterized in that in said microorganism the kfoE gene originally present which encodes an enzyme responsible for the addition of fructose residues to the linear chondroitin backbone is inactivated by deletion or substitution entirely or in part of said gene or disruption by insertion of an additional nucleotide sequence, and wherein the kfoE gene encodes a protein selected from the group consisting of: (A) a protein comprising the amino acid sequence of SEQ ID N°2.