Patent ID: 7153882

Claim:
A compound comprising formula I wherein R 1 and R 2 are, independently, hydrogen, branched or straight chain C 1 –C 8 alkyl, substituted or unsubstituted aryl, or aralkyl; R 3 is branched or straight chain C 1 –C 4 alkyl or heteroalkyl or C 4 –C 8 alkyl or heteroakyl, or substituted or unsubstituted aryl; X and Y are, independently, O, S, alkyl, hydrocarbon moiety, C(H)R 4 , or NR 5 , wherein R 4 and R 5 are, independently, hydrogen, oxygen, branched or straight chain C 1 –C 8 alkyl, C 2 –C 8 alkenyl, or C 2 –C 8 alkynyl, aralkyl, or substituted or unsubstituted aryl; wherein the compound is the substantially pure (+)-enantiomer, wherein the proviso that the compound is not (+)-physostigmine, (+)-octylcarbamoyleseroline, (+)-benzylcarbamoyleseroline, (+)-physovenine, (+)-N-methylphysostigmine, (+)-phenserine, (+)-3-(1-methylamino)-ethyl-2H-indol-5yl-phenylcarbamate, (+)-N 1 -benzylnorphysostigmine, (+)-N 1 -benzylnorphenserine, (+)-N 1 -benzylnortolserine, (+)-N 1 -benzylnorcymserine, (+)-N 1 -norphysostigmine, (+)-N 1 -norphenserine, (+)-N 1 -nortolserine, (+)-N 1 -norcymserine, (+)-N 8 -benzylnorphysostigmine, (+)-N 8 -benzylnorphenserine, (+)-N 8 -norphysostigmine, (+)-N 8 -norphenserine, (+)-N 1 , N 8 -bisbenzylnorphysostigmine, (+)-N 1 , N 8 -bisbenzylnorphenserine, (+)-N 1 ,N 8 -bisnorphysostigmine, or (+)-N 1 ,N 8 -bisnorphenserine, with the proviso that when the compound is formula I, X is NCH 3 , and Y is NR 5 , where R 5 is hydrogen, loweralkyl, arylloweralkyl, heteroarylloweralkyl, cycloalkylmethyl, or loweralkenyl methyl, R 3 is not methyl or at least one of R 1 or R 2 is not H or alkyl.