Patent ID: 8058271

Claim:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is halogen, â€”NR 2 , â€”OR, â€”SR, or a C 1-4 alkyl each R 3 is, independently, hydrogen or a C 1-4 aliphatic group; X 1 is CH; T is a bond or a C 1 -C 6 alkylidene chain, wherein up to two methylene units of T are optionally and independently replaced by â€”NRâ€²â€”, â€”Sâ€”, â€”Oâ€”, â€”C(O)NRâ€²â€”, â€”NRâ€²C(O)â€”, â€”NRâ€²C(O)Oâ€”, â€”S(O) 2 NRâ€²â€”, â€”NRâ€²S(O) 2 â€”, â€”NRâ€²C(O)NRâ€²â€”, â€”OC(O)NRâ€²â€”, or â€”NRâ€²S(O) 2 NRâ€²â€”; each R 5 is, independently, R a or halogen; n is 1 to 3; each occurrence of R a is, independently, hydrogen, an optionally substituted moiety selected from a C 1-4 alkyl group, a C 3-6 cycloalkyl group, a C 1-4 haloalkyl group, or a heterocyclic ring selected from morpholino, piperidinyl, or piperazinyl; each optionally substituted group or ring is optionally substituted with 1-5 substituents independently selected from C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 haloalkyl, halogen, or â€”ORâ€³; each occurrence of R is, independently, hydrogen, a C 1-4 alkyl group, a C 3-6 cycloalkyl group, â€”(CH 2 ) 1-2 Ph, â€”CHâ•CHPh, or a C 1-4 haloalkyl group; each occurrence of Râ€² is, independently, hydrogen or a C 1-4 alkyl group; and each occurrence of Râ€³ is, independently, hydrogen or a C 1-4 alkyl group.