Patent ID: 7947713

Claim:
A compound of formula (I) a stereochemically isomeric form thereof, or a pharmaceutically acceptable addition salt thereof, wherein n is an integer 0; X represents —(CR 4 R 5 ) m — wherein m is an integer 1 or 2; R 4 and R 5 are each independently from each other hydrogen or C 1-4 alkyl; R 1 is C 1-6 alkylcarbonyl optionally substituted with hydroxy; C 1-6 alkyloxycarbonyl; aminoC 1-6 alkylcarbonyl wherein the C 1-6 alkyl group is optionally substituted with C 3-6 cycloalkyl; mono- and di(C 1-4 alkyl)aminoC 1-6 alkylcarbonyl; aminocarbonyl substituted with aryl; C 1-6 alkylcarbonyloxyC 1-6 alkylcarbonyl; C 1-6 alkyloxycarbonylaminoC 1-6 alkylcarbonyl wherein the amino group is optionally substituted with C 1-4 alkyl; an amino acid bound via the carbonyl group; C 1-6 alkyl substituted with amino; or arylcarbonyl; R 2 is a 5-membered heterocycle selected from wherein m′ is an integer 1 to 2; R 6 is hydrogen or C 1-4 alkyl; R 7 is independently from each other halo; amino; hydroxy; trifluoromethyl; C 1-6 alkyl; C 1-4 alkyl substituted with hydroxy, hydroxycarbonyl, C 1-4 alkyloxycarbonyl, aminocarbonyl, mono- or di(C 1-4 alkyl)aminocarbonyl, amino, or mono- or di(C 1-4 alkyl)amino; phenyl; aminocarbonyl; hydroxycarbonyl; C 1-4 alkyloxycarbonyl; C 1-4 alkylcarbonyl; or C 1-4 alkyloxycarbonylC 1-4 alkylaminocarbonyl; or R 2 is benzimidazole, or benzimidazole substituted with one or two substituents each independently selected from halo, trifluoromethyl, C 1-4 alkyl, hydroxy, hydroxycarbonyl, or C 1-4 alkyloxycarbonyl; R 3 is a bivalent radical of formula wherein said (b-1), (b-2), or (b-3) optionally can be substituted with one, two or three substituents each independently selected from halo, hydroxy, C 1-6 alkyl, C 1-6 alkyloxy, nitro, amino, cyano, trifluoromethyl, phenyl, or phenyl substituted with one or two substituents each independently selected from halo, hydroxy, cyano, C 1-6 alkyl, C 1-6 alkyloxy, nitro, cyano, and trifluoromethyl; aryl is phenyl, or phenyl substituted with amino, nitro or hydroxycarbonyl.