Patent ID: 8609689

Claim:
A compound of the formula (I) wherein: one atom among Y and W is a nitrogen atom and the other atoms from Y and W, and also X and Z, are a carbon atom substituted by a substituent selected from: hydrogen, or T; A is: aryl, heteroaryl, cycloalkyl, aryloxyalkyl, arylalkoxyalkyl, arylthioalkyl, arylalkylthioalkyl, heteroarylalkyl, heteroaryloxyalkyl, heteroarylalkoxyalkyl, heteroarylthioalkyl, heteroarylalkylthioalkyl, heterocycloalkylalkyl, heterocycloalkyloxyalkyl, heterocycloalkylalkoxyalkyl, heterocycloalkylthioalkyl, heterocycloalkylalkylthioalkyl, arylalkenyl, or arylalkynyl; the heteroaryl or heterocycloalkyl groups having one or more heteroatom selected from N, O and S; each of these groups optionally substituted by one or more substituents selected from T; R1 is: alkyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyloxyalkyl, heterocycloalkylalkoxyalkyl, heterocycloalkylthioalkyl, heterocycloalkylalkylthioalkyl, R3R4N-alkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; each of these groups optionally substituted by one or more substituents selected from T; T is: hydroxy, thio, halogen, trifluoromethoxy, trifluoromethyl, carboxy, carboxymethyl, carboxyethyl, alkyl, cycloalkyl, alkoxy, alkylamino, aryl, arylsulfonylalkyl, aryloxy, arylalkoxy, NR3R4, azido, nitro, guanidino, phosphono, oxo, carbamoyl, alkylsulfonyl, alkylsulfinyl, alkylthio, or SF 5 , or two T groups together form methylenedioxy; R3 and R4 are independently selected from: hydrogen, lower alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; or R3 and R4 together form a heterocycloalkyl group which has one or more heteroatoms selected from N, O and S; and R3 and R4 are independently optionally substituted by one or more substituents selected from T; as well as its racemic forms, tautomers, enantiomers, diastereomers and epimers, and mixtures thereof, and the pharmaceutically acceptable salts thereof.