Patent ID: 8779132

Claim:
A compound having the formula (VIII): wherein Q 1 is a bond or a group CH 2 ; R 1 is hydroxy or O—R z and R 2a is hydroxy or O—R z ; provided that at least one of R 1 and R 2a is O—R z ; R z is L p -R p1 ; SO 3 H; a glucuronide residue; a mono-, di- or tripeptide residue; or L p is C═O, (C═O)O, (C═O)NR p1 or S(O) x NR p1 ; x is 1 or 2; R p1 is hydrogen or a C 1-25 hydrocarbyl group containing 0, 1 or 2 carbocyclic rings and 0, 1, 2, 3, 4, 5 or 6 carbon-carbon multiple bonds, the C 1-25 hydrocarbyl group being optionally substituted by hydroxy, amino, mono- or di-C 1-6 alkylamino, C 1-6 acylamino, halogen or C 1-4 alkoxy or C 1-4 alkyl groups wherein the C 1-4 alkoxy or C 1-4 alkyl groups are each optionally substituted by two or more fluorine atoms; and wherein up to 3 non-terminal carbon atoms in the C 1-25 hydrocarbyl group may optionally be replaced by oxygen, and up to one pair of adjacent non-terminal carbon atoms may optionally be replaced by C(═O)O or O(C═O); provided that R p1 is not hydrogen when L p is C═O or (C═O)O; and provided also that O—R z does not contain an O—O moiety; and R p2 and R p3 are the same or different and each is a group R p1 .