Patent ID: 7528153

Claim:
Deoxynojirimycin analogue, or a pharmaceutically acceptable salt thereof, having the general structure (I) wherein R 1 -R 5 each independently comprise H or (CH 2 ) n CH 3 or X; n is 0-9 R 6 comprises H, CH 2 OH or CH 2 OX; m is 0 or 1; a, b, c, d, e are chiral centers having an R or S configuration; and X comprises a large hydrophobic moiety and a spacer, whereby the hydrophobic moiety is linked through the spacer to the nitrogen atom or carbon atom concerned, and wherein the large hydrophobic moiety is derived from a polycyclic alcohol containing three or more rings each sharing two or more carbon atoms with one of the other rings and is capable of inserting in lipid bilayers.