Patent ID: 8846839

Claim:
A medical device comprising a supporting structure having a coating associated therewith, the coating comprising a polymer having the formula in which, R 1 -R 4 are independently a methacryl, acryl, styryl, acrylamido, methacrylamido, sulfovinyl, amido, ester, ethyl, or propyl; R 5 is a hydrocarbon chain, cycloaliphatic group, ester group, amide group, thiol, sulfone, carbonate, saccharide, PEG, or combination thereof; R 6 includes a zwitterion group, a linker being a chain of 2-12 carbon atoms, and an ester or amide attachment to the methacryl group; R 7 is a methyl, ethyl, or hydrogen group; n is in a range from about 0.005 to about 0.5; o is in a range from about 0.005 to about 0.4; p is in a range from 0 to about 0.25; q is in a range from 0 to about 0.98; and r is in a range from 0 to about 0.4; wherein the zwitterion group has a formula selected from the group consisting of wherein the moieties A 2 and A 3 , which are the same or different, are —O—, —S—, —NH— or a valence bond, W + is a group comprising an ammonium, phosphonium or sulphonium cationic group and a group linking the anionic and cationic moieties which is a C 1-12 -alkanediyl group; -A 4 -R 3 —N + (R 4 ) 2 —R 5 —V − ,wherein (II) A 4 is a valence bond, —O—, —S—, or —NH—; V is a carboxylate or phosphate diester (monovalently charged) anion; R 3 is a valence bond (together with A 4 ) or alkanediyl, —C(O)alkylene- or —C(O)NH alkylene; the groups R 4 are the same or different and each is hydrogen or alkyl of 1 to 4 carbon atoms or the groups R 4 together with the nitrogen to which they are attached form a heterocyclic ring of 5 to 7 atoms; and R 5 is an alkyanediyl of 1 to 20 carbon atoms, of 1 to 10 carbon atoms, or of 1 to 6 carbon atoms; and wherein A 5 is a valence bond. —O—, —S—, or —NH—; R 16 is a valence bond (optionally together with A 5 ) or alkanediyl, —C(O)alkylene- or —C(O)NH alkylene; the groups R 17 are the same or different and each is hydrogen or alkyl of 1 to 4 carbon atoms or the groups R 17 together with the nitrogen to which they are attached form a heterocyclic ring of 5 to 7 atoms.