Patent ID: 7696210

Claim:
A compound of the formula I: or a pharmaceutically acceptable salt thereof, wherein: A is optionally substituted phenyl; B is (CR 13 R 14 ) k -D; D is: each D also having up to three R 19 substituents attached to the ring of D containing at least one N; R 16 is hydrogen, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, R 20 -E-R 21 , C(═O)ER 20 , ER 20 , NR 20 R 21 , or (CH 2 ) n G, optionally substituted alkyl, optionally substituted aryl, aryl substituted with optionally substituted alkyl, alkyl substituted with optionally substituted aryl, alkyl substituted with imidazole, alkyl substituted with optionally substituted imidazole, or alkyl substituted with indole; R 17 is hydrogen, C 1 -C 6 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, (CH 2 ) m CO 2 R 20 , (CH 2 ) m C(═O)NR 20 R 21 ; R 19 is H, C 1 -C 3 alkyl, alkenyl, or alkynyl; or alternatively, R 16 and R 19 , taken together with the atoms to which they are attached, form a cyclic or heterocyclic group; R 20 and R 21 are, independently, H, C 1 -C 3 alkyl, or heteroalkyl, or alternatively, R 20 and R 21 , taken together with the atoms to which they are attached, form a cyclic or heterocyclic group; m is 0, 1, or 2; n is 0, 1, 2, 3, or 4; X is O, NR 21 , or SO m ; E is O, N, NR 21 , or SO m ; G is phenyl, 2-pyridyl, 3-pyridyl or 4-pyridyl; k is 0, 1, 2, or 3; R 1 is H or optionally substituted alkyl; R 2 , R 3 , and R 4 are H; R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , and R 12 , are, independently, H or optionally substituted alkyl; R 13 and R 14 are, independently at each occurrence, H or optionally substituted alkyl.