Patent ID: 8470597

Claim:
A method for treating a patient with a skin defect, consisting of: (a) providing said patient with a composite consisting of an N-isopropylacrylamide (NIPAAm) layer polymerized with a) a biodegradable layer and b) a layer of polypropylene (PP) non-woven, wherein said biodegradable layer consists of gelatin and a glutaraldehyde crosslinking agent, and wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivated on and is present on the biodegradable layer; (b) covering the skin defect of the patient with said composite; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven; wherein the skin defect is a wound resulting from trauma or burn injury.