Patent ID: 7943606

Claim:
A compound represented by the formula: wherein R 1 and R 3-8 are independently hydrogen, C 1 -C 26 straight, branched or cyclic alkanes or alkenes, aromatic hydrocarbons, alcohols, ethers, aldehydes, ketones, carboxylic acids, amines, amides, nitriles, or five- and/or six-membered heterocyclic moieties; wherein R 2 is —CH 2 —O-L-N+(R 11 , R 12 , R 13 ); or —O—CH 2 -L-N + (R 11 , R 12 , R 13 ); wherein Y is —S—, —Se—, —CH 2 —, —NH— or —O—; wherein L is a C 1 -C 4 straight alkane, alkene, thiol, ether, or amine; wherein R 11 , R 12 and R 13 are independently C 1 -C 4 straight alkanes, alkenes, thiols, amines, ethers or alcohols; wherein Z − is Cl − , Br − or I − ; and wherein the compound may be administered in a suitable carrier at a therapeutically effective dose to an untreated or treated mammal or human with cancer to reduce tumor size or to treat loss of lean body weight as a consequence of composition-induced reduction in tumor size, or both.