Patent ID: 8513218

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt or boronic acid anhydride thereof, wherein: A is 0, 1, or 2; P is hydrogen or an amino-group-blocking moiety; each R a2 independently is hydrogen, C 1-6 aliphatic, C 1-6 fluoroaliphatic, —(CH 2 ) m —CH 2 —R B , —(CH 2 ) m —CH 2 —NHC(═NR 4 )NH—Y, —(CH 2 ) m —CH 2 —CON(R 4 ) 2 , —(CH 2 ) m —CH 2 —N(R 4 )CON(R 4 ) 2 , —(CH 2 ) m —CH(R 6 )N(R 4 ) 2 , —(CH 2 ) m —CH(R 5 )—OR 5 , or —(CH 2 ) m —CH(R 5 )—SR 5 ; each Y independently is hydrogen, —CN, —NO 2 , or —S(O) 2 R 10 ; each R B independently is a substituted or unsubstituted mono- or bicyclic ring system; each R 4 independently is hydrogen or a substituted or unsubstituted aliphatic, aryl, heteroaryl, or heterocyclyl group; or two R 4 on the same nitrogen atom, taken together with the nitrogen atom, form a substituted or unsubstituted 4- to 8-membered heterocyclyl ring having, in addition to the nitrogen atom, 0-2 ring heteroatoms independently selected from N, O, and S; each R 5 independently is hydrogen or a substituted or unsubstituted aliphatic, aryl, heteroaryl, or heterocyclyl group; each R 6 independently is a substituted or unsubstituted aliphatic, aryl, or heteroaryl group; each R 10 independently is C 1-6 aliphatic, C 6-10 aryl, or —N(R 4 ) 2 ; m is 0, 1, or 2; and Z 1 and Z 2 are each independently hydroxy, alkoxy, aryloxy, or aralkoxy; or Z 1 and Z 2 together form a moiety derived from a boronic acid complexing agent.