Patent ID: 7563785

Claim:
A method of modulating sleep in a subject, comprising administering a therapeutically effective amount of a compound of Formula IV to a subject in need thereof: or a pharmaceutically effective salt thereof, wherein: t is 1 or 2; R 2 , R 3 , R 6 , and R 7 are, independently, selected from H, F, Cl, Br, CF 3 , OH, CH 3 , OCH 3 , CH 2 OCH 3 , and CH 2 OCH 2 CH 3 ; R 9 and R 10 are, independently, H, CH 3 , CH 2 CH 3 , or R 9 and R 10 , together with the carbon to which they are attached, are connected to form a three-membered spirocyclopropyl ring; Z is selected from CO 2 H and provided that when Z is COOH and R 6 is H, F, Cl, or Br, then R 2 , R 3 , R 7 , R 9 , and R 10 are not each hydrogen.