Patent ID: 7531546

Claim:
A compound of formula I, or a pharmaceutically acceptable salt thereof: wherein E is a radical of formula b wherein A is CH 2 , CH 2 —CH 2 or C═O; L is H, OCH 3 , halo, or lower alkoxy; Q is H, lower alkyl, hydroxy substituted lower alkyl, optionally substituted aryl lower alkyl, lower alkyl sulfonyl, carbocyclic aryl lower alkyl, lower alkoxy-substituted carbocyclic aryl lower alkyl, halo-substituted carbocyclic aryl lower alkyl, N-heterocyclyl-substituted lower alkyl, lower alkoxy substituted carbocyclic aryl, amino carbonyl, cycloalkyl amino carbonyl, N-heterocyclyl substituted lower alkyl carbonyl, halo-substituted carbocyclic aryl lower alkyl, lower alkoxy carbonyl, or lower alkyl carbonyl; and R is lower alkyl, para-chlorophenylethyl, cyclohexylethyl, dimethylbutyl, difluorocyclohexylethyl, cyclopentylethyl or cycloheptylethyl.