Patent ID: 7388003

Claim:
Δ 15 -D-Homosteroids of formula I, wherein R 1 stands for a C 1-4 -alkyl group, and R 2 stands for a hydroxy group, a formyloxy group, a group OC(O)—R 20 , OC(O)NH—R 20 , or OR 20 , whereby R 20 means a C 1-12 -alkyl group, a C 3-8 -cycloalkyl group, an aryl group or an aryl-C 1-4 -alkyl group, which optionally is substituted, and R 3 stands for a hydrogen atom or a C 1-6 -alkyl-, vinyl-, ethinyl- or C n F 2n+1 group, with n=1, 2, 3, and R 4 stands for a hydrogen atom, or R 2 stands for a hydrogen atom or a C 1-6 -alkyl-, vinyl-, ethinyl- or C n F 2n+1 group, with n=1, 2, 3, R 3 stands for a hydroxy group, a group OC(O)—R 20 , OC(O)NH—R 20 or OR 20 , whereby R 20 means a C 1-12 -alkyl group, a C 3-8 -cycloalkyl group, an aryl group or an aryl-C 1-4 -alkyl group, which optionally is substituted, and R 4 stands for a hydrogen atom, or R 2 and R 3 together stand for an oxygen atom, and R 4 stands for a hydrogen atom, or R 2 stands for a hydroxy group, a formyloxy group, a group OC(O)—R 20 , OC(O)NH—R 20 or OR 20 , whereby R 20 means a C 1-12 -alkyl group, a C 3-8 -cycloalkyl group, an aryl group or an aryl-C 1-4 -alkyl group, which optionally is substituted, and R 3 and R 4 together form a double bond, and STEROID stands for a steroidal ABC partial ring system of formulas A, B, C, D, E and F: whereby an additional double bond can be found in A and C in 1,2-position, and one or two additional double bonds can be found in B in 9,10-position and 11,12-position, R 7 means a hydrogen atom, a halogen atom, a hydroxy group or a C n F 2n+1 group, with n=1, 2, 3, X means an oxygen atom, two hydrogen atoms or a hydroxyimino group, R 8 means a hydrogen atom, a methyl or ethyl group, R 9 means a hydrogen atom or a halogen atom or together with R 10 stands for a double bond, R 10 means a hydrogen atom, a hydroxy group, a methyl or ethyl group or together with R 9 stands for a double bond, R 11 means a hydrogen atom, a C 1-4 -alkyl group, a nitrile group, a hydroxymethylene group or formyl group, R 12 means a hydrogen atom, a C 1-4 -alkyl group or a nitrile group, R 11 and R 12 , in addition to the above-mentioned meanings, together mean a methylene bridge, R 13 means a hydrogen atom or together with R 7 means a double bond, R 16 means a hydrogen atom or together with R 13 means a double bond, R 15 means a hydroxyl group, R 14 and R 15 stand for a hydrogen atom or together for a double bond, a [2,3c]oxadiazole ring, a [3,2c]isoxazole ring or a [3,2c]pyrazole ring, and R 17 means a hydrogen atom or a methyl group, Y stands for an oxygen or nitrogen atom, whereby the wavy lines at R 4 , R 7 , R 8 , R 11 , R 12 , R 13 , R 14 and R 15 mean that these substituents can be in α- or β-position, with the proviso that 17aβ-Hydroxy-D-homo-androstane-4,15-dien-3-one is excluded.