Patent ID: 8436005

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein G 1 is C 3 -alkylene; G 2 is C 1 -alkylene; wherein each carbon of the alkylene groups of G 1 and G 2 may be optionally substituted with one or more groups selected from acyl, acyloxy, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkyl, alkylcycloalkyl, alkylsulfonyl, alkylthio, alkynyl, amido, carboxy, cyano, cyanoalkyl, cycloalkoxyalkyl, cycloalkyl, fluoro, fluoroalkoxy, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, formyl, haloalkoxy, haloalkyl, halogen, hydroxy, hydroxyalkyl, mercapto, nitro, and oxo; G 4 is a bond; R 1 is NH 2 , —NH(acyl), —NH(alkyl), —N(alkyl) 2 , —NH(C═O)aryl, —NH-alkylene(NR 8 R 9 ), —NH(C═O)-alkylene(NR 8 R 9 ), —NR 8 (C═O)NR 8 R 9 , —NH-alkylene-heteroaryl, —NHOH, or —NHOCH 3 ; R 6 at each occurrence is independently hydrogen, alkoxyalkyl, alkyl, alkylcycloalkyl, cyanoalkyl, cycloalkoxyalkyl, cycloalkyl, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, or hydroxyalkyl; R 7 is alkoxyalkyl, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, or hydroxyalkyl; R 8 and R 9 at each occurrence are independently hydrogen, acyl, alkoxyalkyl, alkoxycarbonyl, alkyl, alkylcycloalkyl, alkylsulfonyl, amido, aryl, cyanoalkyl, cycloalkoxyalkyl, cycloalkyl, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, formyl, heteroaryl, heterocycle, hydroxy, or hydroxyalkyl; R 10 is independently hydrogen, acyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, alkyl, alkylcycloalkyl, alkylsulfonyl, amido, aryl, arylalkyl, cyanoalkyl, cycloalkoxyalkyl, cycloalkyl, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, formyl, heteroaryl, heterocycle, hydroxy, or hydroxyalkyl; R 11 is independently hydrogen, acyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, alkyl, alkylcycloalkyl, alkylsulfonyl, amido, aryl, arylalkyl, cyanoalkyl, cycloalkoxyalkyl, cycloalkyl, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, formyl, heteroaryl, heterocycle, hydroxy, or hydroxyalkyl; A 1 is wherein, n is 1, 2, or 3; and m is 0, 1, or 2; wherein each carbon atom of groups A 1 may be optionally substituted with one or more groups selected from acyl, acyloxy, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkyl, alkylcycloalkyl, alkylsulfonyl, alkylthio, alkynyl, amido, carboxy, cyano, cyanoalkyl, cycloalkoxyalkyl, cycloalkyl, fluoro, fluoroalkoxy, fluoroalkyl, fluorocycloalkyl, fluorocycloalkylalkyl, formyl, haloalkoxy, haloalkyl, halogen, hydroxy, hydroxyalkyl, mercapto, and nitro.