Patent ID: 6933313

Claim:
A compound of the formula (I): Z is cyclohexenyl, or phenyl, R 20 is selected from groups (a), (b) and (c) where; (a) is —(C 1 -C 20 )alkyl, —(C 2 -C 20 )alkenyl, —(C 2 -C 20 )alkynyl, carbocyclic radicals, or heterocyclic radicals, or (b) is a member of (a) substituted with one or more substituents selected from hydrogen, —(C 1 -C 6 )alkyl, —(C 2 -C 6 )alkenyl, —(C 2 -C 6 )alkynyl, —(C 3 -C 8 )cycloalkyl,″ —(C 1 -C 8 )alkoxy, halogen or phenyl (C 1 -C 4 )alkyl, (c) is the group —(L)—R 80 ; where, (L)— is a divalent linking group of 1 to 12 atoms selected from carbon, hydrogen, R 21 is hydrogen, —(C 1 -C 6 )alkyl, —(C 2 -C 6 )alkenyl, —(C 2 -C 6 )alkynyl, —(C 3 -C 8 )cycloalkyl,″ —(C 1 -C 6 )alkoxy, halogen or phenyl (C 1 -C 4 )alkyl, where f is 1-3; R 1 is —NHNR 30 R 31 , —NR 30 R 31 , or —CONR 30 R 31 , where R 30 and R 31 are each independently hydrogen or —(C 1 -C 6 )alkyl; R 2 is —CONR 40 R 41 , where R 40 —OH, —O(C 1 -C 8 )alkyl, —O(C 2 -C 8 )alkenyl, —O(C 3 -C 8 )cycloalkyl, —O(aryl) and —O(C 1 -C 8 )alkylaryl; and R 41 is hydrogen, —(C 1 -C 8 )alkyl, —(C 2 -C 8 )alkenyl, —(C 3 -C 8 )cycloalkyl, aryl and —(C 1 -C 8 )alkylaryl; where j is 1 to 3 both inclusive; and R 3 is selected from hydrogen, —(C 1 -C 6 )alkyl, —(C 2 -C 6 )alkenyl, —(C 2 -C 6 )alkynyl, —(C 3 -C 8 )cycloalkyl,″ —(C 1 -C 6 )alkoxy, halogen, phenyl (C 1 -C 4 )alkyl, optionally substituted carbocyclic and optionally substituted heterocyclic, wherein the substituent is selected from hydrogen, —(C 1 -C 6 )alkyl, —(C 2 -C 6 )alkenyl, —(C 2 -C 6 )alkynyl, —(C 3 -C 8 )cycloalkyl,″ —(C 1 -C 6 )alkoxy, halogen and phenyl (C 1 -C 4 )alkyl, or a pharmaceutically acceptable solvate or salt, thereof.