Patent ID: 8483828

Claim:
An implantable device for delivering cardiac therapy to a patient, comprising: one or more pulse generators for incorporating into one or more pacing channels for delivering pacing pulses and for incorporating into a parasympathetic stimulation channel for delivering neural stimulation pulse in order to stimulate parasympathetic nerve activity; a sensor for measuring blood pressure; a controller for controlling the delivery of pacing pulses to one or more ventricular sites during a cardiac cycle in accordance with a programmed pacing mode; wherein the controller is programmed to deliver remodeling control therapy (RCT) by controllably delivering ventricular pacing in a manner which pre-excites a region of the ventricular myocardium so as to mechanically unload that region during systole; wherein the controller is further programmed to deliver anti-remodeling therapy (ART) by controlling stimulation of parasympathetic nerve activity via the parasympathetic stimulation channel; wherein the controller is programmed to perform an assessment of cardiac function and to modulate the delivery of the RCT and ART in accordance with the assessment of cardiac function, wherein the assessment of cardiac function includes a measurement of blood pressure; and, wherein the ART is modulated in response to the assessment of cardiac function by varying the amplitude of the neural stimulation pulses.