Patent ID: 8603758

Claim:
A method of diagnosing prostate cancer in a subject comprising: (a) obtaining a tissue sample from the prostate of a human subject; (b) determining in the sample a level of expression for PKC-ι, wherein said determining step comprises: contacting the sample with an antibody that recognizes PKC-ι protein in an immunoassay selected from western blot assay, enzyme-linked immunosorbent assay (ELISA), and immunohistochemical assay, and detecting the complex between the antibody and the PKC-ι protein; (c) comparing the expression level determined in (b) to a control, wherein the control is a level of expression of PKC-ι in a benign human prostate tissue; and (d) informing the human subject as having prostate cancer if the PKC-ι expression level determined in (b) is higher than the control or informing the human subject as not having prostate cancer if the PKC-ι expression level determined in (b) is lower than the control.