Patent ID: 8067040

Claim:
A method of preparing and analyzing granules comprising Ramulus cinnamomi extract and Poria cocos extract, the method comprises the steps of: a) grinding Poria cocos into fine powder to yield Poria Powder; b) extracting Cortex moutan by steam distillation to give a Paeonol extract and a Solid Residue I; c) extracting the Solid Residue I with ethanol to give Extract I, and then extracting said Solid Residue I again with hot water to give Extract II; d) extracting Ramulus cinnamomi by steam distillation to give a volatile oil and a Solid Residue II; e) extracting the Solid Residue II with ethanol to give Extract III, and then extracting said Solid Residue II again with hot water to give Extract IV; f) extracting Radix paeoniae alba, Semen persicae , and Poria cocos with ethanol to give Extract V, and then extracting said Radix paeoniae alba, Semen persicae , and Poria cocos again with hot water to give Extract VI; g) combining Extracts I, III and V, and removing all ethanol to give Liquid A; h) combining Extracts II, IV and VI, and concentrating the combined extracts to give Liquid B; i) combining Liquids A and B, and concentrating the liquids to give a Semisolid Extract with a relative density equal to 1.15-1.35 (60-90° C.); j) dissolving the Paeonol extract from step (b) in ethanol, and adding the solution to an aqueous solution of beta-cyclodextrin, wherein the mixture is grinded and dried to give Inclusion Substance I; k) mixing the volatile oil from step (d) with beta-cyclodextrin in ethanol, wherein the mixture is grinded and dried to give Inclusion Substance II; i) mixing the Poria Powder from step (a) with the Semisolid Extract from step (i), wherein the mixture is dried and grinded into fine powders; (m) mixing the fine powders from step (i) with Inclusion Substances I and II, adding ethanol to the mixture to make a dough-like mass, and passing the wet material through a sieve to obtain granules; and (n) drying said granules, and passing the dried granules through the sieve again to give final granules comprising Ramulus cinnamomi extract and Poria cocos extract; and (o) analyzing the granules by high performance liquid chromatography to produce a fingerprint of 12 peaks.