Patent ID: 8372842

Claim:
A compound selected from Formula I: and stereoisomers and pharmaceutically acceptable salts thereof, wherein: G is phenyl optionally substituted by 1-3 independent R 4 groups, or when m is 0, G may additionally be absent or C 1 -C 4 alkyl; R 1 is selected from hydrogen, halogen, CN, C 1 -C 4 alkyl optionally substituted with halogen, —OR e , C 3 -C 6 cycloalkyl, 5 or 6 membered heteroaryl, phenyl or —O-phenyl, wherein the heteroaryl, phenyl or —O-phenyl may be optionally substituted with one or two R b groups; R 2 is selected from hydrogen, CH 3 , CH 2 CH 3 , CF 3 , C 2 -C 4 alkenyl optionally substituted with one or two R c groups, NHR a or —OR f , provided that when R 1 is hydrogen, then R 2 is —OR f ; R 3 is selected from hydrogen or C 1 -C 4 alkyl; R 4 is selected from halogen, CF 3 , OCF 3 and CN; R 5 and R 6 are independently selected from hydrogen or CH 3 ; R 7 and R 8 are independently selected from hydrogen or C 1 -C 6 alkyl; R 9 is hydrogen or CH 3 ; R a is hydrogen or a five to six membered heterocycle optionally substituted with an oxo group; R b is halogen; R c is OH, OCH 3 , oxo, or a 5 to 6 membered heteroaryl; R e is C 1 -C 4 alkyl optionally substituted with OH or a 5-6 membered heterocycle; R f is C 1 -C 4 alkyl optionally substituted with one or more OH groups; m, n and p are independently 0 or 1; or R 5 is hydrogen, R 6 and R 7 together with the atoms to which they are attached form an optionally substituted 5-6 membered heterocyclic ring having one ring nitrogen atom, and R 8 is selected from the group consisting of hydrogen or C 1 -C 4 alkyl optionally substituted with OH or O(C 1 -C 3 alkyl), such that the compound of Formula I has the structure of Formula II: wherein R c and R d are independently selected from hydrogen or C 1 -C 4 alkyl; and r is 1 or 2.