Patent ID: 7642277

Claim:
A compound of formula 1: Ar 1 —X—W—Ar 2 1 wherein Ar 1 is wherein R 12 is selected from the group consisting of R 13 represents Cl, Br, COO(C 1-4 )alkyl and if R 9 is NO 2 , Cl or Br, then R 13 may also represent F or CH 3 ; R 14 , R 15 , R 31 , R 32 , R 33 are each independently selected from the group consisting of H, (C 1-6 )alkyl, (C 3-7 )cycloalkyl, (C 3-7 )cycloalkyl-(C 1-3 )alkyl, (C 2-6 )alkenyl, O—(C 1-4 )alkyl, S-(C 1-4 )alkyl, halo, CF 3 , OCF 3 , OH, NO 2 , CN, SO 2 NH 2 , SO 2 —(C 1-4 )alkyl, C(O)OR 1 wherein R 1 is H or (C 1-4 )alkyl, or NR 2 R 3 wherein R 2 and R 3 each independently is H or (C 1-4 )alkyl; R 30 represents H, Cl, Br, COO(C 1-4 )alkyl; and X is S or O; W is CH 2 C(O)NR 6 wherein R 6 is H or (C 1-4 )alkyl; and Ar 2 is selected from the group consisting of wherein R 9 is halo or NO 2 ; and if R 13 is Cl or Br, then R 9 may also represent (C 1-3 )alkyl; R 10 , R 11 are independently of each other selected from the group consisting of H, (C 1-6 )alkyl, (C 3-7 )Cycloalkyl, (C 3-7 )Cycloalkyl-(C 1-3 )alkyl, (C 2-6 )alkenyl, O(C 1- 6 )alkyl, S(C 1-6 )alkyl, halo, CF 3 , OCF 3 , OH, NO 2 , CN, —NR N1 R N2 , —C(O)R 21 , —(C 1-3 )alkyl-C(O)R 21 , —C(O)OR 22 , —(C 1-3 )alkyl-C(O)OR 22 , —SO 2 —(C 1-3 )alkyl-C(O)OR 22 , wherein R 21 is (C 1-4 )alkyl and R 22 is H or (C 1-4 )alkyl; —(C 1-3 )alkyl-C(O)NH 2 , C(O)NH 2 , S(O)—(C 1-6 )alkyl, —SO 2 —(C 1-6 )alkyl, —SO 2 -phenyl, —SO 2 —NH 2 , phenyl, phenylmethyl, 2-, 3- or 4-pyridinyl, 1-pyrrolyl, whereby said phenyl, pyridinyl and pyrrolyl may have one or more substituents selected from the group consisting of halo, NO 2 , C 1-3 -alkyl and CF 3 ; wherein R N1 , R N2 each independently represent H or (C 1-6 )alkyl, whereby R N1 and R N2 may be covalently bonded to each other to form together with the N-atom to which they are attached to a 4 to 7-membered heterocycle whereby the —CH 2 -group at the position 4 of a 6 or 7-membered heterocycle may be replaced by —O—, —S— or —NR N3 - wherein R N3 represents H, —C(O)OR 22 , (C 1-6 )alkyl,(C 3-7 )cycloalkyl or (C 3-7 )cycloalkyl-(C 1-3 )alkyl, wherein R 22 is H or (C 1-4 )alkyl; or a pharmaceutically acceptable salt thereof.