Patent ID: 7135495

Claim:
An indole derivative compound represented by formula (I): wherein R 1 represents —COR 6 , R 6 represents a hydroxyl group, C1–6 alkoxy group, —NR 8 R 9 , C1–6 alkoxy group substituted by phenyl group, or C2–6 alkenyloxy group, R 8 and R 9 represent hydrogen atom, C1–6 alkyl group or —SO 2 R 10 , R 10 represents C1–6 alkyl group, carbocyclic ring or heterocycle, D represents a single bond, C1–6 alkylene group, C2–6 alkenylene group, or —O—(C1–6 alkylene)- group, R 2 represents C1–6 alkyl group, C1–6 alkoxy group, halogen atom, trihalomethyl group, cyano group, or hydroxyl group, R 3 and R 4 each independently represent a hydrogen atom, C1–6 alkyl group, and C1–6 alkoxy group, C1–6 alkyl group substituted by C1–6 alkoxy group, a halogen atom, nitro group, —NR 11 R 12 , trihalomethyl group, cyano group, hydroxyl group, or trihalomethoxy group, R 11 and R 12 represent a hydrogen atom or C1–6 alkyl group, m represents 1 to 4, n represents 1 to 4, R 5 represents C1–6 alkyl group substituted by C1–6 alkoxy group, or C1–6 alkoxy group substituted by C1–6 alkoxy group, G represents a single bond, C1–6 alkylene group, which may be substituted by hydroxyl group or C1–4 alkoxy group, wherein each of 1 or 2 carbon atoms of the C1–6 alkylene group independently may be replaced by an oxygen atom or a sulfur atom, C2–6 alkenylene group, which may be substituted by hydroxyl group or C1–4 alkoxy group, wherein each of 1 or 2 carbon atoms of the C2–6 alkenylene group independently may be replaced by an oxygen atom or a sulfur atom, —CONR 13 —, —NR 14 CO—, —SO 2 NR 15 —, —NR 16 SO 2 —, or —N═N—, R 13 , R 14 , R 15 , and R 16 each independently represent a hydrogen atom or C1–6 alkyl group, represents carbocyclic ring or heterocycle, carbocyclic ring represents C3–15 monocycle, dicyclic or tricycle carbocyclic ring aryls that may be saturated all or partially, heterocycle represents C6 monocyclic, dicyclic, or tricyclic heterocyclic ring aryls that may be saturated all or partially, which contain 2 hetero atom(s) independently selected from oxygen atom and nitrogen atom, each carbocyclic ring and each heterocycle independently may be substituted by 1–5 group(s) selected from C1–6 alkyl group, C1–10 alkoxy group, C1–6 alkyl group substituted by C1–6 alkoxy group, halogen atom, hydroxyl group, trihalomethyl group, nitro group, —NR 17 R 18 , phenyl group, phenoxy group, oxo group, C2–6 acyl group, cyano group, and —SO 2 R 19 , R 17 and R 18 each independently represent hydrogen atom or C1–6 alkyl group, R 19 represents C1–6 alkyl group, and represents a single bond or a double bond, except for 2-(1-(4-benzyloxybenzoyl)-2-methyl-5-methoxyindol-3-yl) acetic acid methyl or a non-toxic salt thereof.