Patent ID: 7371829

Claim:
An antibody for use in a method for detecting ketamine and norketamine, said antibody possessing a cross-reactivity of 100-175% for norketamine and a cross-reactivity of 100% for ketamine, wherein said antibody is raised against an immunogen comprising a norketamine hapten, wherein said norketamine hapten is derivatised with a crosslinker at the nitrogen of the norketamine, wherein the norketamine hapten has the following structural formula: wherein R is a bivalent link and X is a terminal group, wherein R is an alkylene moiety; and X is selected from the group comprising a carboxylic acid or an ester thereof, an amine, a maleimide, a halocarboxylic acid or an ester thereof, an aldehyde, a dithiopyridyl moiety, a vinylsulphone moiety or a thiocarboxylic acid or an ester thereof and said antibody binds at least one structural epitope of each of norketamine and ketamine.