Patent ID: 8143276

Claim:
A compound of the formula II: wherein: X is C—H; r is 0 to 6; s is 0 to 6; n is 0 to 3; A is selected from an aryl group; each R 2 is —(CH 2 ) v —N(R 22 )(R 23 ) wherein: each R 22 and R 23 are independently selected from H, alkyl, cycloalkyl, cycloalkenyl, alkyl-O-alkyl, alkyl-O-aryl, alkenyl, alkynyl, aralkyl, aryl and a heterocyclic group; or R 22 and R 23 may be taken together with the nitrogen to which they are attached form a 5- to 7-membered ring which may optionally contain a further heteroatom and may be optionally substituted with up to three substituents selected from halo, CN, NO 2 , alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, aryl, and a heterocyclic group; v is 0 to 6; p is 1 R 3 is selected from the group consisting of H, alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, aryl, a heterocyclic group, —(CH 2 ) x C(O)R 31 , —(CH 2 ) x C(O)N(R 32 )(R 33 ), (CH 2 ) x C(O)OR 31 , R 31 is selected from H, alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, aralkyl, aryl and a heterocyclic group; R 32 and R 33 are independently selected from H, alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, aralkyl, aryl and a heterocyclic group; or R 32 and R 33 may be taken together with the nitrogen to which they are attached to form a 5- to 7-membered ring which may optionally contain a further heteroatom and may be optionally substituted with up to three substituents selected from halo, CN, NO 2 , alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, aryl, and a heterocyclic group; and x is 0 to 6; or a pharmaceutically acceptable salt thereof.