Patent ID: 7645761

Claim:
A method of inducing contraception in a mammal, the method comprising administering to a mammal in need thereof a pharmaceutically effective amount of a compound of the structure: wherein: R 1 and R 2 form a double bond to C(CH 3 ) 2 , C(cycloalkyl), O, or C(cycoether); R 3 is selected from the group consisting of H, OH, NH 2 , C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, C 3 to C 6 alkenyl, alkynyl, substituted alkynyl, and COR A ; R A is selected from the group consisting of H, C 1 to C 3 alkyl, substituted C 1 to C 3 alkyl, C 1 to C 3 alkoxy, substituted C 1 to C 3 alkoxy, C 1 to C 3 aminoalkyl, and substituted C 1 to C 3 aminoalkyl; R 4 is selected from the group consisting of H, halogen, CN, NH 2 , C 1 to C 6 alkyl, substituted C 1 to C 6 alkyl, C 1 to C 6 alkoxy, substituted C 1 to C 6 alkoxy, C 1 to C 6 aminoalkyl, and substituted C 1 to C 6 aminoalkyl; R 5 is a five membered ring of the structure: wherein: U is O, S, or NR 6 , R 6 is H, C 1 to C 3 alkyl, or C 1 to C 4 CO 2 alkyl, X′ is selected from the group consisting of halogen, CN, NO 2 , C 1 to C 3 alkyl and C 1 to C 3 alkoxy; with the proviso that when X′ is CN, U is not NR 6 ; Y′ is selected from the group consisting of H, F, CN, NO 2 , and C 1 to C 4 alkyl; or a pharmaceutically acceptable salt thereof.