Patent ID: 7714126

Claim:
A compound of the formula (I): wherein: R 1 is phenyl or phenyl substituted with a group selected from the group consisting of alkyl, —O-alkyl, haloalkoxy, methoxy-ethoxy, halogen, or cycloalkyl containing 4 to 7 carbon atoms; R 2 is C; R 3 is N; R 4 is S or O; R 5 is C; R 6 is H, alkyl, halogen, haloalkyl, or thioalkyl; R 7 is wherein one of R 8 and R 9 is nitrogen and the other is carbon; R 10 is —NR 11 R 12 , O-alkyl, hydroxy-dimethylethylamino, hydroxyl-methylethylamino, cyclohept-2-ylamino, morpholino, thiomorpholino, oxothiomorpholino, dioxothiomorpholino, alkyl-carbamoyl-alkyl-amino, difluoroazetidine, ethoxyazetidine, or a 4- to 6-membered cyclic ring having from 1 to 3 hetero ring atoms selected from the group consisting of S, N and O substituted with a group selected from the group consisting of amino, —N(CH 3 )C(O)CH 3 , cyclopropanecarbonyl-methyl, —OCH 3 , —OCH 2 C(O)OC(CH 3 ) 3 , OCH 2 C(O)OH, —CH 2 OH, —CH 2 OCH 3 and —OH; R 11 is H, lower alkyl, alkoxyalkyl, alkyl-aryl, trifluoromethyl, cyclopropylmethoxy-ethyl, —CH 2 CH 2 CN, hydroxyalkyl, cycloalkyl, or a 4- to 6-membered cyclic ring having from 1 to 3 hetero ring atoms selected from the group consisting of S, N and O, unsubstituted or substituted with a group selected from the group consisting of —OCH 3 , —CH 2 OH, —CH 2 OCH 3 , —OCH 2 C(O)OC(CH 3 ) 3 , —OCH 2 C(O)OH and —OH; R 12 is H or lower alkyl; or a pharmaceutically acceptable salt thereof.