Patent ID: 7915411

Claim:
A compound, a tautomer of the compound, or a pharmaceutically acceptable salt of the compound or tautomer, wherein the compound has Formula II: wherein: R 6 is selected from the group consisting of hydrogen and cyano; R 8 is selected from the group consisting of hydrogen and arylalkyl; R 25 is selected from the group consisting of hydrogen and alkyl; R 37 is selected from the group consisting of hydrogen, alkyl, hydroxyalkyl, and cycloalkyl; R 42 is selected from the group consisting of arylsulfanyl, heteroarylsulfanyl, and aryloxy; wherein R 42 is optionally substituted with one or more substituents independently selected from R 46 ; R 46 is one or more substituents selected from the group consisting of hydrogen, hydroxy, amino, halogen, dialkylamino, and alkoxycarbonylamino; R 70 is selected from the group consisting of aryl, and heterocyclo; wherein R 70 is optionally substituted with R 75 ; R 75 is one or more substituents independently selected from the group consisting of hydrogen, halogen, alkoxy, cyano, alkyl, haloalkyl, and aryl.