Patent ID: 6903215

Claim:
A compound of Formula (IA) wherein: R 1 is an aryl group optionally independently substituted with one to three substituent groups, wherein each substituent group of R 1 is independently C 1 -C 5 alkyl, C 2 -C 5 alkenyl, C 2 -C 5 alkynyl, C 3 -C 8 cycloalkyl, heterocyclyl, aryl, heteroaryl, C 1 -C 5 alkoxy, C 2 -C 5 alkenyloxy, C 2 -C 5 alkynyloxy, aryloxy, acyl, C 1 -C 5 alkoxycarbonyl, C 1 -C 5 alkanoyloxy, C 1 -C 3 alkanoyl, aroyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, aminocarbonyloxy, C 1 -C 5 alkylaminocarbonyloxy, C 1 -C 5 dialkylaminocarbonyloxy, C 1 -C 5 alkanoylamino, C 1 -C 5 alkoxycarbonylamino, C 1 -C 5 alkylsulfonylamino, aminosulfonyl, C 1 -C 5 alkylaminosulfonyl, C 1 -C 5 dialkylaninosulfonyl, halogen, hydroxy, carboxy, cyano, trifluoromethyl, trifluoromethoxy, nitro, or amino wherein the nitrogen atom is optionally independently mono- or di-substituted by C 1 -C 5 alkyl or aryl; or ureido wherein either nitrogen atom is optionally independently substituted with C 1 -C 5 alkyl; or C 1 -C 1 -C 5 alkylthio wherein the sulfur atom is optionally oxidized to a sulfoxide or sulfone, wherein each substituent group of R 1 is optionally independently substituted with one to three substituent groups selected from methyl, methoxy, halogen, hydroxy, oxo, cyano, or amino, R 2 and R 3 are each independently hydrogen or C 1 -C 5 alkyl; R 4 is C 1 -C 5 alkyl, C 2 -C 5 alkenyl, or C 2 -C 5 alkynyl, each optionally independently substituted with one to three substituent groups, wherein each substituent group of R 4 is independently C 1 -C 3 alkyl, hydroxy, halogen, amino, or oxo; and R 5 is an azaindolyl group optionally independently substituted with one to three substituent groups, wherein each substituent group of R 5 is independently C 1 -C 5 alkyl, C 2 -C 5 alkenyl, C 2 -C 5 alkynyl, C 3 -C 8 cycloalkyl, heterocyclyl, aryl, heteroaryl, C 1 -C 5 alkoxy, C 2 -C 5 alkenyloxy, C 2 -C 5 alkynyloxy, aryloxy, acyl, C 1 -C 5 alkoxycarbonyl, C 1 -C 5 alkanoyloxy, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, aminocarbonyloxy, C 1 -C 5 alkylaminocarbonyloxy, C 1 -C 5 dialkylaminocarbonyloxy, C 1 -C 5 alkanoylamino, C 1 -C 5 alkoxycarbonylamino, C 1 -C 5 alkylsulfonylamino, aminosulfonyl, C 1 -C 5 alkylaminosulfonyl, C 1 -C 5 dialkylaminosulfonyl, halogen, hydroxy, carboxy, cyano, trifluoromethyl, trifluoromethoxy, trifluoromethylthio, nitro, or amino wherein the nitrogen atom is optionally independently mono- or di-substituted by C 1 -C 5 alkyl; or ureido wherein either nitrogen atom is optionally independently substituted with C 1 -C 5 alkyl; or C 1 -C 5 alkylthio wherein the sulfur atom is optionally oxidized to a sulfoxide or sulfone, wherein each substituent group of R 5 is optionally independently substituted with one to three substituent groups selected from C 1 -C 3 alkyl, C 1 -C 3 alkoxy, halogen, hydroxy, oxo, cyano, amino, or trifluoromethyl, or a tautomer, prodrug, solvate, or salt thereof.