Patent ID: 7563806

Claim:
A compound of formula 1 wherein n denotes 0 or 1; m denotes 1, 2, 3 or 4; X denotes a single bond or one of the double-bonded groups C 2 -C 6 -alkenylene, —O—C 1 -C 6 -alkylene, —NH—C 1 -C 6 -alkylene, —S—C 1 -C 6 -alkylene or C 1 -C 6 -alkylene; R 1 and R 2 together denote a double-bonded group selected from —CH 2 —CH 2 —C(O)—NH, —CH═CH—C(O)—NH, wherein in each case one or 2 hydrogen atoms may be replaced by one or two groups selected from —C 1 -C 4 -alkyl, OH, or halogen; R 3 and R 4 which may be identical or different denote a group selected from hydrogen, OH, halogen, —C 1 -C 6 -alkyl, —C 1 -C 6 -haloalkyl, —C 1 -C 6 -hydroxyalkyl, NH 2 , NH(—C 1 -C 4 -alkyl) and N(—C 1 -C 4 -alkyl) 2 ; R 5 , R 6 , R 7 and R 8 , which may be identical or different, denote hydrogen, OR 9 , —C 1 -C 6 -alkyl, —C 1 -C 6 -haloalkyl, —C 1 -C 6 -hydroxyalkyl, —C 3 -C 6 -cycloalkyl, —C 3 -C 6 -hydroxycycloalkyl, —CN, NO 2 , —COR 9 , —COOR 9 , —CONR 10 R 11 , —NR 10 R 11 , —NR 10 COR 9 , —NR 10 SO 2 R 12 , —SR 12 , —SOR 12 , —SO 2 R 12 , —SO 2 NR 10 R 11 or halogen, or two of the groups R 5 , R 6 , R 7 and R 8 , if they are located vicinally to the substituting phenyl ring, together form a double-bonded group selected from C 2 -C 6 -alkylene, C 2 -C 6 -alkenylene and —O—C 1 -C 6 -alkylene-O— wherein in each case one or 2 hydrogen atoms may be replaced by one or two groups selected from —C 1 -C 4 -alkyl, —C 1 -C 4 -alkoxy, OH, or halogen; R 9 denotes hydrogen, C 1 -C 4 -alkyl, C 6 -C 10 -aryl or C 6 -C 10 -aryl-C 1 -C 4 -alkylene; R 10 and R 11 which may be identical or different, denote hydrogen, C 1 -C 4 -alkyl, C 6 -C 10 -aryl or C 6 -C 10 -aryl-C 1 -C 4 -alkylene; R 12 denotes C 1 -C 4 -alkyl, C 6 -C 10 -aryl or C 6 -C 10 -aryl-C 1 -C 4 -alkylene, optionally in the form of the individual optical isomers, mixtures of the individual enantiomers or racemates, in the form of the free bases or the corresponding acid addition salts thereof with pharmacologically acceptable acids.