Patent ID: 7674813

Claim:
A compound of formula (Ia) or a pharmaceutically acceptable salt thereof, of the structure: wherein: R 1 is selected from the group consisting of lower alkyl, substituted lower alkyl, phenyl, substituted phenyl, benzyl, substituted benzyl, benzyloxy, substituted benzyloxy, and SO 2 R 5 ; R 5 is selected from the group consisting of phenyl, substituted phenyl, heterocycle, substituted heterocycle, alkyl, and substituted alkyl; R 2 is selected from the group consisting of lower alkyl, substituted lower alkyl, CF 3 , alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, phenyl, substituted phenyl, and cycloalkyl; R 3 is selected from the group consisting of hydrogen, lower alkyl, and substituted lower alkyl; R 4 is selected from the group consisting of phenyl, substituted phenyl, heterocycle, substituted heterocycle, thiophene, and substituted thiophene; R 6 is selected from the group consisting of hydrogen, lower alkyl, substituted lower alkyl, CF 3 , alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, phenyl, substituted phenyl, cycloalkyl, and substituted cycloalkyl; W, X, and Y are selected from the group consisting of (i), (ii), and (iii): (i) W is N, Y is CR 7 , and X is N; (ii) W is CR 7 , Y is CR 7 , and X is N; and (iii) W is CR 7 , Y is CR 7 , and X is CR 7 ; R 7 is selected from the group consisting of hydrogen, halogen, lower alkyl, and substituted lower alkyl.