Patent ID: 8859001

Claim:
A non-infusion pharmaceutical formulation, comprising a composition formulated for delivery of fenoldopam or a derivative of fenoldopam to the human body, which comprises particles of a size of about 5 to 500 nm in an aqueous medium, comprising: (i) at least one surfactant; (ii) at least one solid component which is a solid at room temperature; (iii) an amphiphilic solvent; and (iv) a compound of the formula wherein either (i) R, R′, R″ and R′″ are H or (ii) R, R′ and R″ are the same or different residues that form an electrostatic salt with the phenolate anion, a metal ion or organometallic molecules that form a complex with one or more phenolic groups, or an organic residue covalently bound to the phenolic residue via a bio-cleavable ester or carbonate bond, and R′″ is a specific residue that forms an electrostatic salt with the amine, a metal ion or atom or an organic residue covalently bound to the amino residue via a bio-cleavable amine, amide, or urea bond.