Patent ID: 7893216

Claim:
A monoclonal antibody which binds specifically to TRAIL receptor DR-5, said monoclonal antibody comprising a light chain which has a variable region, with three CDR regions, wherein CDR1 consists of amino acids 24-39 of SEQ ID NO: 1, CDR2 consists of amino acids 55-61 of SEQ ID NO: 1, and CDR3 consists of amino acids 94-102 of SEQ ID NO: 1, and a heavy chain which has a variable region with three CDR regions wherein the first heavy chain CDR region consists of amino acids 31-35 of SEQ ID NO: 2, the second heavy chain CDR region consists of amino acids 50-66 of SEQ ID NO: 2, and the third heavy chain CDR region consists of amino acids 99-101 of SEQ ID NO: 2.