Patent ID: 8101764

Claim:
A compound of formula: wherein: “-----” is optionally a bond to form a double bond; R 1 is independently selected from the group consisting of hydrogen, C 1 -C 4 alkyl, halo, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, and —O—C 3 -C 4 cycloalkyl; R a and R b are independently hydrogen, fluoro, chloro, or methoxy; R 2 is hydrogen or methyl; L 1 is selected from the group consisting of a bond, —OCH 2 CH 2 —, —OCH 2 CH 2 CH 2 —, —C(O)NCH 2 CH 2 —, —C(O)CH 2 CH 2 —, NHC(O)CH 2 —, and —NHC(O)CH 2 CH 2 —; —NHC(O)CH 2 CH 2 CH 2 —, and —C(O)NHCH 2 CH 2 CH 2 —R 3 and R 4 combine together with the nitrogen atom to which they are attached to form an optionally substituted 4 to 7-member heterocyclic ring; or one of R 3 and R 4 combines with L 1 at a position α, β, γ, or, δ to the nitrogen of NR 3 R 4 to form a nitrogen containing 4 to 7-member heterocyclic ring with L 1 ; wherein each 4 to 7 member nitrogen containing heterocyclic ring formed by R 3 and R 4 or L 1 and either of R 3 and R 4 is optionally substituted with one or two groups independently selected from the group consisting of oxo, hydroxy, —OR 6 , C 1 -C 4 alkyl, halo, C 1 -C 4 haloalkyl, —C 1 -C 3 alkylalcohol, —C(O)C 1 -C 3 alkyl, C 3 -C 6 cycloalkyl, NR 6 R 6′ , and C 1 -C 4 alkylNR 6 R 6′ ; R 5 is hydrogen, halo, cyano, methyl, and methoxy; R 6 and R 6′ are independently selected from the group consisting of hydrogen, C 1 -C 4 alkyl, —C 1 -C 3 alkylalcohol, —C 1 -C 3 haloalkyl, and C 3 -C 4 cycloalkyl, or R 6 and R 6′ combine together with the nitrogen atom to which they are attached to form a 4 to 6 member nitrogen containing heterocyclic ring optionally substituted with a group selected from halo, C 1 -C 2 alkyl, and hydroxy; or a pharmaceutically acceptable salt, or enantiomer, diastereomer or mixture of diastereomers thereof.