Patent ID: 7022723

Claim:
A heterocyclic compound of the formula [1], or a pharmaceutically acceptable salt thereof: R 1 -Het-D-E [1] wherein: R 1 is aryl; said aryl being optionally substituted by the same or different one to three groups selected from alkyl, haloalky, trihaloalkyl, alkoxy, halogen and nitro; Het is an oxazole which is optionally substituted by alkyl or trihaloalkyl; D is alkylene, alkenylene, or alkynylene; and E is a group of the formula [4]: wherein Y is oxygen or sulfur; R 3 and R 4 are the same or different and each being hydrogen or alkyl; Z is carboxy, alkoxycarbonyl, hydroxymethyl, carbamoyl, N-hydroxycarbamoyl, N-alkylcarbamoyl, N,N-dialkylcarbamoyl, cyano, 1H-5-tetrazolyl, 1-alkyl-5-tetrazolyl, or 2-alkyl-5-tetrazolyl, with the proviso that compounds are excluded in which: 1) D is methylene and Y is sulfur; and 2) D is alkylene and Y is oxygen.