Patent ID: 7601749

Claim:
A compound having Formula IV: or a pharmaceutically acceptable salt, ester or amide thereof, where said ester is derived from a C 1-6 alcohol and said amide is derived from a C 1-6 amine, wherein: the dotted line is a single or double bond; R 1 is selected from H, optionally substituted C 1-10 alkyl, optionally substituted C 2-10 alkenyl, optionally substituted C 2-10 alkynyl, optionally substituted C 1-10 alkylaryl, optionally substituted C 1-10 alkylheteroaryl, optionally substituted -C 1-10 alkyl-O-C 1-10 alkyl, optionally substituted -C 1-10 alkyl-O-aryl, optionally substituted -C 1-10 alkyl-O-heteroaryl, optionally substituted aryl, and optionally substituted heteroaryl; R 2 , R 2a , R 3 and R 3a are independently selected from H, halogen, and C 1-10 alkyl, wherein R 2a and R 3a are present only when the carbons to which they are attached are saturated; or R 2 and R 3 taken together with the carbon atoms to which they are attached, form an optionally substituted saturated, unsaturated, or aromatic 5- or 6-membered ring; or R 2 and R 2a taken together with the carbon atoms to which they are attached, form an optionally substituted saturated 3-6 membered ring; R 4 is H, C 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, or halogen, wherein R 4 is present only when the carbon to which it is attached is saturated; R 5 is H, C 1-10 alkyl, perhaloalkyl, C 2-10 alkenyl, C 2-10 alkynyl, C 1-10 alkylaryl, C 1-10 alkylheteroaryl, aryl, or heteroaryl, wherein said aryl or heteroaryl is optionally substituted with one or more substituents selected from C 1-10 alkyl, halogen, C 1-10 alkoxy, and CN; R 6 is one or more H, halogen, C 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, CN, OR 7 , SR 7 , aryl or heteroaryl groups; and R 7 is H, C 2-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, aryl, or heteroaryl, wherein unless otherwise specified, optional substituents are selected from C 1-10 alkyl, halogen, halo C 1-10 alkyl, halo C 1-10 alkoxy, cycloalkyl, hydroxy, cyano, aryl, aryloxy, carbamoyl, aralkyl, heteroaryl, heteroaryloxy, alkoxycarbonyl, amino, acyloxy, arylacyloxy, heterocyclo, heterocycloalkoxy, partially unsaturated heterocycylalkyl and partially unsaturated heterocyclylalkoxy, and where each optional substituent may be further substituted with one or more C 1-6 alkly, halogen, halo C 1-10 alkyl, C 1-10 alkoxy, haloalkoxy, aryl, or heteroaryl groups.