Patent ID: 7626023

Claim:
A compound selected from the group consisting of: N,β,β,3-Tetramethyl-L-phenylalanyl-N 1 -[(1S,2E)-1-isopropyl-3-methyl-4-(4-methylpiperazin-1-yl)-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β,3,4-Pentamethyl-L-phenylalanyl-N 1 -[(1S,2E)-1-isopropyl-3-methyl-4-(4-methylpiperazin-1-yl)-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β,3,5-Pentamethyl-L-phenylalanyl-N 1 -[(1S,2E)-1-isopropyl-3-methyl-4-(4-methylpiperazin-1-yl)-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β,3,4-Pentamethyl-L-phenylalanyl-N 1 -[(1S,2E)-4-(4-benzylpiperazin-1-yl)-1-isopropyl-3-methyl-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β,3,4-Pentamethyl-D-phenylalanyl-N 1 -[(1S,2E)-4-(4-benzylpiperazin-1-yl)-1-isopropyl-3-methyl-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β,3,5-Pentamethyl-L-phenylalanyl-N 1 -[(1S,2E)-4-(4-benzylpiperazin-1-yl)-1-isopropyl-3-methyl-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β,3-Tetramethyl-L-phenylalanyl-N 1 -[(1S,2E)-4-(4-benzylpiperazin-1-yl)-1-isopropyl-3-methyl-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; 3-Chloro-N,β,β-trimethyl-L-phenylalanyl-N 1 -[(1S,2E)-4-(4-benzylpiperazin-1-yl)-1-isopropyl-3-methyl-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β-trimethyl-L-phenylalanyl-N 1 -[(1S,2E)-1-isopropyl-3-methyl-4-(4-methyl-1-piperazinyl)-4-oxo-2-butenyl]-N 1 ,3-dimethyl-L-valinamide; N,β,β-trimethyl-L-phenylalanyl-N 1 -((1S,2E)-4-{4-[3-(dimethylamino)propyl]piperazin-1-yl}-1-isopropyl-3-methyl-4-oxobut-2-enyl)-N 1 ,3-dimethyl-L-valinamide; and N,β,β-trimethyl-L-phenylalanyl-N 1 -[(1S,2E)-4-(4-benzylpiperazin-1-yl)-1-isopropyl-3-methyl-4-oxobut-2-enyl]-N 1 ,3-dimethyl-L-valinamide; or pharmaceutically acceptable salts thereof.