Patent ID: 7947706

Claim:
A compound of formula (I): wherein: 1) A and Ar are independently selected from the group consisting of: aryl, heteroaryl, substituted aryl, substituted heteroaryl, cycloalkyl, and substituted cycloalkyl; 2) L is selected from the group consisting of: bond, CO, NH, CO—NH, NH—CO, NH—SO, NH—SO 2 , SO 2 NH, NH—CH 2 , CH 2 —NH, CH 2 —CO—NH, NH—CO—CH 2 , NH—CH 2 —CO, CO—CH 2 —NH, NH—CO—NH, NH—CS—NH, and NH—CO—O, O—CO—NH; 3) one from among Y and Z is chosen from N and NO, and the other from among Y and Z is C(R5), and W is C(R6); 4) R1, R5, and R6 are each independently chosen from the group consisting of: H, halogen, R2, CN, O(R2), OC(O)(R2), OC(O)N(R2)(R3), OS(O 2 )(R2), N(R2)(R3), N═C(R2)(R3), N(R2)C(O)(R3), N(R2)C(O)O(R3), N(R4)C(O)N(R2)(R3), N(R4)C(S)N(R2)(R3), N(R2)S(O 2 )(R3), C(O)(R2), C(O)O(R2), C(O)N(R2)(R3), C(═N(R3))(R2), C(═N(OR3))(R2), S(R2), S(O)(R2), S(O 2 )(R2), S(O 2 )O(R2), and S(O 2 )N(R2)(R3); in which each R2, R3, R4 is independently selected from the group consisting of H, alkyl, alkylene, alkynyl, aryl, heteroaryl, cycloalkyl, heterocyclyl, substituted alkyl, substituted alkylene, substituted alkynyl, substituted aryl, substituted heteroaryl, substituted cycloalkyl, substituted heterocyclyl, alkylene, substituted alkylene, and substituted alkynyl; in which, when R2 and R3 are simultaneously present on one of the groups R1, R5 and R6, they may be linked together to form a ring; 5) Ra is selected from the group consisting of H, (C1-C4)alkyl and (C3-C4)cycloalkyl; or a pharmaceutically acceptable salt, hydrate or solvate of the compound of formula (I).