Patent ID: 8530454

Claim:
A method for the treatment of psoriasis, comprising administering to a subject having psoriasis, an effective amount of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, or isomer thereof, wherein the compound of Formula (I) is: wherein: R 1 is —(CH 2 ) a Y or —CH═CH—(CH 2 ) p Z; Y is —SO 3 H, —SO 3 R 3 , —PO 3 H, —PO 3 − .X + , or —PO 3 R 3 , wherein when Y is —SO 3 H, —SO 3 − .X + or —SO 3 R 3 , then R 9 and R 9 ′ are independently selected from —OH and —OR 2 , wherein at least one of R 9 and R 9 ′ is a substituted or unsubstituted alkylsulfonyloxy group, a substituted or unsubstituted arylsulfonyloxy group, a substituted or unsubstituted alkylcarbonyloxy group or a substituted or unsubstituted arylcarbonyloxy group; Z is —SO 3 H, —SO 3 − .X + , —SO 3 R 3 , —PO 3 H, —PO 3 − .X + , —PO 3 R 3 , —CO 2 H, —CO 2 − .X + or —CO 2 R 3 ; X + is an organic cation or an inorganic cation, such that the general charge of the compound is neutral; R 9 and R 9 ′ are independently selected from —OH and —OR 2 , wherein when R 9 and R 9 ′ are both —OR 2 , then said R 9 and R 9 ′ can be the same or different; R 2 is a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkylsulfonyl group, a substituted or unsubstituted arylsulfonyl group, a substituted or unsubstituted alkylcarbonyl group or a substituted or unsubstituted arylcarbonyl group; R 3 is a substituted or unsubstituted alkyl group or a substituted or unsubstituted aryl group; a is a number selected from 0, 1, 2, 3, 4, 5 and 6; and p is an integer selected from 0, 1, 2, 3, 4, 5 and 6.