Patent ID: 8362249

Claim:
A compound of formula (I): wherein: A is N; B is C or N; X is —NHC(O)—; Y is —C(O)NH—; R 1 is H, —CN, halogen, —CF 3 , —OCF 3 , C 1-3 alkyl, C 1-3 alkoxy, —S(O) m CH 3 , amino, mono- or dimethylamino, —NHC(O)C 1-3 alkyl, —NO 2 —C(O)NH 2 , —C(O)NHC 1-3 alkyl or —C(O)C 1-3 alkyl; R 2 is aryl, heteroaryl or C 3-10 cycloalkyl each optionally substituted with one to three R 7 ; R 3 is heteroaryl, heterocyclyl, aryl or C 3-10 cycloalkyl each optionally substituted with one to three R 8 ; R 4 is H or C 1-6 alkyl; R 5 and R 6 are each independently selected from H, C 1-2 alkyl and phenyl; R 7 is —OH, oxo, hydroxyC 1-6 alkyl, halogen, —(CH 2 ) m —CN, nitro, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-10 cycloalkyl, C 1-6 alkoxy, phenoxy, heteroaryloxy, C 1-6 alkoxycarbonyl, carboxyl, —C(O)C 1-6 alkyl, —(CH 2 ) m —NR 9 R 10 , —S(O) m C 1-6 alkyl, —NHS(O) 2 C 1-6 alkyl, NR 9 C(O)C 1-6 alkyl, —S(O) 2 NR 9 R 10 , —C(O)NR 9 R 10 heterocyclyl, heteroaryl, phenyl or benzyl, wherein each alkyl, alkenyl, alkynyl or alkoxy is optionally partially or fully halogenated and each heterocycle, heteroaryl, phenyl or benzyl of said R 7 is optionally substituted with one to three C 1-6 alkyl, C 1-6 alkoxy(CH 2 ) m , halogen, —CN, —CF 3 , C 1-6 acyl, —NR 9 R 10 , —C(O)NR 9 R 10 , —OH, hydroxyC 1-6 alkyl or —S(O) m C 1-6 alkyl; R 8 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, carboxyl, C 3-10 cycloalkyl, C 1-6 alkoxy, halogen, oxo, or phenyl, wherein each alkyl, alkenyl, alkynyl, cycloalkyl or alkoxy is optionally partially or fully halogenated; R 9 and R 10 are independently selected from hydrogen, C 1-6 alkyl, C 1-6 acyl, C 3-10 cycloalkyl, hydroxyC 1-6 alkyl, C 1-6 alkylC 1-6 alkoxy, C 1-6 alkylsulfonyl and C 1-6 alkoxycarbonyl; m is 0-2; n is 1; is a single bond if A is N, or a single or double bond if A is C; or a pharmaceutically acceptable salt thereof.