Patent ID: 8785131

Claim:
A method of determining prognosis of lung cancer in a human patient, the method comprising: (a) obtaining a biological sample from a human patient classified as having early stage non-small cell lung cancer; (b) contacting the biological sample with a set of chromosomal probes comprising at least two probes selected from the group consisting of a chromosome 10q23.3 locus specific probe and a chromosome 10 enumeration probe under conditions sufficient to enable hybridization of probes in the set to chromosomes in the sample, if any; (c) identifying a hybridization pattern of the set of chromosomal probes to the biological sample; and (d) determining prognosis of lung cancer in the subject based upon the hybridization pattern identified in step (c), wherein the hybridization pattern is identification of a ratio of the number of probe signals for the chromosome locus 10q23.3 to the number of probe signals of chromosome 10, wherein a ratio of less than 0.80 indicates non favorable prognosis.