Patent ID: 8722629

Claim:
A compound of the formula (I) or its salt, hydrate, or hydrate of the salt, in which R 1 is hydrogen, (C 1 -C 6 )-alkyl or a group of the formula Q 1 -L 1 -* or Q 2 -L 2 -* in which * denotes the point of attachment to the nitrogen atom, Q 1 is hydroxycarbonyl, (C 1 -C 4 )-alkoxycarbonyl or benzyloxycarbonyl, L 1 is a straight-chain (C 1 -C 12 )-alkcanediyl which is optionally substituted up to four times by methyl and in which (a) two carbon atoms are optionally bridged in 1,2-, 1,3- or 1,4-relation to one another including any carbon atoms located between them to form a (C 3 -C 6 )-cycloalkyl ring or a phenyl ring or (b) up to three CH 2 groups not adjacent to one another are optionally replaced by —O—, Q 2 is hydroxyl, amino or mono-(C 1 -C 4 )-alkylamino, and L 2 is a straight-chain (C 2 -C 12 )-alkanediyl which is optionally substituted up to four times by methyl and in which (a) two carbon atoms are optionally bridged in 1,2-, 1,3- or 1,4-relation to one another including any carbon atoms located between them to form a (C 3 -C 6 )-cycloalkyl ring or a phenyl ring or (b) up to three CH 2 groups not adjacent to one another are optionally replaced by —O—, R 2 is methyl or hydroxyl, R 3 is hydrogen or methyl, R 4 is isopropyl, isobutyl, sec-butyl, tert-butyl, phenyl, benzyl, 4-hydroxybenzyl, 4-hydroxy-3-nitrobenzyl, 1-phenylethyl, diphenylmethyl, 1H-imidazol-4-ylmethyl or 1H-indol-3-ylmethyl, or R 3 and R 4 together with the carbon atom to which both are attached form a 2-phenyl-cyclopropane-1,1-diyl group of the formula in which # denotes the points of attachment to the adjacent nitrogen atom and the carbonyl group and ring A with the N—O grouping contained therein is a mono- or bicyclic, optionally substituted heterocycle of the formula in which ** denotes the point of attachment to the carbonyl group, R 5 and R 6 each is hydrogen, hydroxyl, (C 1 -C 4 )-alkcoxy or benzyloxy, and R 7 is hydrogen, fluorine, chlorine, cyano, methyl or trifluoromethyl.