Patent ID: 7700634

Claim:
An (indol-3-yl)-heterocycle having the general Formula I wherein A represents a 5-membered aromatic heterocyclic ring, wherein X 1 , X 2 and X 3 are independently selected from N, O, S and CR; R is H or (C 1-4 )alkyl; R 1 is cyclohexyl or tetrahydropyranyl; R 2 is H, CH 3 or CH 2 —CH 3 ; R 3 and R 4 are independently H or (C 1-6 )alkyl the alkyl groups being optionally substituted with OH, (C 1-4 )alkyloxy, (C 1-4 )alkylthio, (C 1-4 )alkylsulfonyl, CN or halogen; or R 3 together with R 4 and the N to which they are bonded form piperidine, pyrrolidine, morpholine or thiomorpholine, optionally substituted with OH, (C 1-4 )alkyl, (C 1-4 )alkyloxy, (C 1-4 )alkyloxy-(C 1-4 )alkyl, or halogen; or R 3 together with R 5 forms a 4-8 membered ring optionally containing a further heteroatom selected from O and S, and which is optionally substituted with OH, (C 1-4 )alkyl, (C 1-4 )alkyloxy, (C 1-4 )alkyloxy-(C 1-4 )alkyl, or halogen; or R 5 is H or (C 1-4 )alkyl; or R 5 together with R 3 forms a 4-8 membered ring optionally containing a further heteroatom selected from O and S, and which is optionally substituted with OH, (C 1-4 )alkyl, (C 1-4 )alkyloxy, (C 1-4 )alkyloxy-(C 1-4 )alkyl, or halogen; R 5 ′ is H or (C 1-4 )alkyl; R 6 represents 1-3 substituents independently selected from H, (C 1-4 )alkyl, (C 1-4 )alkyloxy, CN and halogen; R 7 is H, (C 1-4 )alkyl, (C 1-4 )alkyloxy, CN or halogen; or or a pharmaceutically acceptable salt thereof.