Patent ID: 7189692

Claim:
A pseudopeptidic osteogenic growth polypeptide (OGP) analog having the general formula: wherein Z-M represent NHC(O), C(O)NH, CH 2 NH, NH 2 CH 2 , N(CH 3 )C(O), C(O)N(CH 3 ), C(O)O, OC(O), OR (CH 2 ) 1 where 1 is an integer of from 2 to 6 and A, B, D and E, which may be the same or different, represent CONH, CH 2 NH, CH 2 S, CH 2 O, NHCO, N(CH 3 )CO, (CH 2 ) 2 , CH═CH, C(O)CH 2 , CH 2 SO or C(O)O, n and m each represent an integer of from 1 to 6, X and Y, if in the ortho or para positions, each represent OH, OCH 3 , F, Cl, Br, CF 3 , CN, NO 2 , NH 2 , NH(CH 3 ) 2 , SH, SCH 3 , CH 2 OH, NHC(O)CH 3 , C(O)OH, C(O)OCH 3 , C(O)NH 2 , C(O)NH 2 , C(O)NHCH 3 , C(O)N(CH 3 ) 2 , or CH 3 , and Y, if in the meta position, represents C(O)C 6 H 5 , C(O)CH 3 , C 6 H 5 , CH 2 C 6 H 5 , and, if in the ortho or para positions can additionally represent C(O)C 6 H 5 , C(O)CH 3 , C 6 H 5 , CH 2 C 6 H 5 , CH 2 CH 3 , CH(CH 3 ) 2 , or C 6 H 11 .