Patent ID: 8461371

Claim:
A method of enantioselective addition to imines, comprising: reacting R 3 CH═NY with R 4 ZnR 5 in the presence of a compound represented by the following formula (I), wherein each of R 1 and R 2 independently is alkyl, or R 1 and R 2 taken together is (CH 2 ) m X(CH 2 ) n ; each of R 3 , R 4 and R 5 , independently, is alkyl, alkenyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; X is O, S or CH 2 ; Y is P(O)Ph 2 ; and each of m and n, independently, is 1, 2 or 3, and the sum of m and n is 3 or 4.