Patent ID: 6984643

Claim:
A compound of Formula (I): wherein: Ar 1 is aryl; Ar 2 is hydrogen, cycloalkyl, aryl or heteroaryl; Z is —C(═O)— or a single bond; R 1 , R 2 , R 3 , R 4 and R 5 are independently hydrogen or alkyl optionally substituted with hydroxy; alk is an alkylene chain of one to six carbon atoms; X is —O—, —NR b -(where R b is hydrogen or alkyl), (CR 6 R 7 ) m (where R 6 and R 7 are independently in each occurrence hydrogen or alkyl and m is an integer from 0 to 3), or —S(O) n — (wherein n is an integer from 0 to 2); or predrugs and pharmaceutically acceptable salts thereof.