Patent ID: 8148366

Claim:
A compound of formula (I), or stereoisomers thereof: in which: R 1 represents a hydrogen atom or a —(CH 2 ) m —NH 2 , —(CH 2 ) m —NH(C 1 -C 6 )alk, —(CH 2 ) m —N[(C 1 -C 6 )alk] 2 , —(CH 2 ) m —NH —C(NH)NH 2 or —(CH 2 ) m —NH—CH═NH radical, in which m is 1 or 2; R 2 and R 3 together form a pyrazolyl, substituted on a nitrogen atom by R 4 ; R 4 represents a hydrogen atom, or a (C 1 -C 6 )alk radical or a chain of formula: -(A) n -(NH) o —(CH 2 ) p —(CHR′) q R″ A represents a C═O, C═NH or SO 2 group; R′ represents a hydrogen atom or a carboxy group; R″ represents a hydrogen atom or an NH 2 , NH(C 1 -C 6 )alk, N[(C 1 -C 6 )alk] 2 , CONH 2 , CONH(C 1 -C 6 )alk, CON[(C 1 -C 6 )alk] 2 group, a saturated heterocycle with 5 or 6 vertices containing 1 or 2 nitrogen atoms, or a saturated heterocycle with 5 or 6 vertices containing 1 or 2 nitrogen atoms and another heteroatom chosen from oxygen and sulphur, fixed to the chain by a nitrogen atom or by a carbon atom and optionally substituted by a (C 1 -C 6 )alk radical; n, o and q independently represent 0 or 1 and p represents 0, 1, 2, 3, or 4; R 5 represents an OSO 3 H, OCHFCO 2 H or OCF 2 CO 2 H group; wherein: R 1 is different from hydrogen, —(CH 2 ) m —NH 2 , —(CH 2 ) m —NH(C 1 -C 6 )alk or —(CH 2 ) m —N[C 1 -C 6 )alk] 2 when R 4 is hydrogen, —(C 1 -C 6 )alk, —(C═O) n —(CH 2 )( 0-5 )—NH 2 , —(C═O) n —(CH 2 ) (0-5 )—NH(C 1 -C 6 )alk or —(C═O) n —(CH 2 ) (0-5) —N[(C 1 -C 6 )alk] 2 and R 5 is an OSO 3 H group, or when R 4 has all of the values of R″ above except for the saturated heterocycle as defined above, and n, o, p and q cannot all be equal to 0 except when R″ is hydrogen or a CONH 2 , CONH(C 1 -C 6 )alk, CON[(C 1 -C 6 )alk] 2 group, or a saturated heterocycle; and or wherein the compound is a free base or a pharmaceutically acceptable salt form.