Patent ID: 7041449

Claim:
A method for screening a compound for the ability to inhibit expression pattern of biomarker sequences that are differentially expressed with age in mice comprising the steps of: (a) dividing test mice into first and second groups; (b) exposing the first group to a test compound; (c) analyzing samples of the first and second groups for the expression pattern of biomarker sequences M21050 (SEQ ID NO: 1), U49430 (SEQ ID NO: 2), K02782 (SEQ ID NO: 3), X66295 (SEQ ID NO: 4), and X82648 (SEQ ID NO: 5); and (d) comparing the analysis of the first and second groups and identifying test compounds that inhibit the expression pattern of the biomarker sequences of said analyzing step (c) in the first group such that the expression patterns are decreased relative to the second group and thus more similar to those observed in biologically younger animals.