Patent ID: 8003693

Claim:
A method of inhibiting fatty acid amide hydrolase activity in a mammal having pain, anxiety or depression, said method comprising administering to the mammal a therapeutically effective amount of a compound of the formula wherein X is O or S; Q is O or S; R is unsubstituted naphthyl or naphthyl substituted with halogen, —OR′, —NR′R″, —SR′, —OC(O)R′, —C(O)R′, —CO 2 R′, —CONR′R″, —OC(O)NR′R″, —NR″C(O)R′, —NR′—C(O)NR″R″′, —NR″C(O) 2 R′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —CN and —NO 2 , —R′, fluoro(C 1 -C 4 )alkoxy, or fluoro(C 1 -C 4 )alkyl, wherein R′, R″, R″′ and R″″ are preferably independently selected from hydrogen and (C 1 -C 8 )alkyl, and R 1 and R 2 are independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, wherein the substituents are independently selected from —OR′, ═O, ═NR′, ═N—OR′, —NR′R″, —SR′, -halogen, —OC(O)R′, —C(O)R′, —CO 2 R′, —CONR′R″, —OC(O)NR′R″, —NR″C(O)R′, —NR′—C(O)NR″R″′, —NR″C(O) 2 R′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —CN and —NO 2 ; wherein R′, R″, R″′ and R″″ are defined as above; and the pharmaceutically acceptable salts thereof, and whereby the anxiety, pain, or depression is treated.