Patent ID: 7112319

Claim:
A method of diagnosing and/or monitoring a neurological disorder in a mammal comprising: generating a temporally and/or spatially resolved Broderick probe microvoltammogram of said mammal; determining from said microvoltammogram the presence and concentration of a marker selected from the group consisting of serotonin, dopamine, ascorbic acid, norepinephrine, γ-aminobutyric acid, glutamate, neurotensin, somatostatin, dynorphin, homovanillic acid, uric acid, tryptophan, tyrosine, nitrous oxide, and nitric oxide; and comparing said marker concentration to a threshold value of said respective marker, wherein said threshold value is derived from a Broderick probe microvoltammogram of a mammal that does not have said neurological disorder, wherein the concentration of said marker differs from said threshold value, and wherein said neurological disorder is selected from the group consisting of athetoid, dystonic diseases, epilepsy, Lesch-Nyhan disease, disorders of the basal ganglia, white matter disease, cerebral hemorrhage, head trauma, multiple sclerosis, central nervous system infection, hydrocephalus, and Leukodystrophies.