Patent ID: 8808979

Claim:
A method for diagnosing liver enzyme induction as a predisposition for liver toxicity and diseases or disorders accompanied therewith comprising: (a) determining the amount of at least five of the following analytes: Stearic acid (C18:0), Galactose, Lignoceric acid (C24:0), Behenic acid (C22:0), Nervonic acid (C24:1), 3- and 5-Methoxysphingosine, Cholesterol, Threonic acid, Phosphatidylcholine (C18:0/C18:2), 1,2-Dioleoyl-sn-glycero-3-phosphatidyl-L-serine, Eicosapentanoic acid, Phosphatidylcholine (C18:0/C22:6) in a test bodyfluid sample of a male subject suspected to suffer from liver enzyme induction; or at least five of the following analytes: Glycerol, Palmitic acid (C16:0), Linoleic acid (C18:cis[9,12]2), Stearic acid (C18:0), Arachidonic acid (C20:cis-[5,8,11,14]4), Docosahexaenoic acid (C22:cis[4,7,10,13,16,19]6), Cholesterol, Glycerolphosphate, Galactose, Lignoceric acid (C24:0), Dodecanol, Heptadecanoic acid (C17:0), Eicosanoic acid (C20:0), myo-Inositol-2-monophosphate, Behenic acid (C22:0), Nervonic acid (C24:1), gamma-Linolenic acid (C18:cis[6,9,12]3), 3- and 5-Methoxysphingosine, Threonic acid, Phosphatidylcholine (C18:2, C20:4), Phosphatidylcholine (C18:0/C18:2) in a test bodyfluid sample of a female subject suspected to suffer from liver enzyme induction as a predisposition for liver toxicity and diseases or disorders accompanied therewith; (b) comparing the amounts determined in step (a) to a reference; and, thereby, (c) diagnosing liver enzyme induction as a predisposition for liver toxicity and diseases or disorders accompanied therewith.