Patent ID: 8389550

Claim:
A compound of formula I wherein L is —CH 2 —CH 2 — or —CH═CH—; R 1 is lower-alkyl or aryl, wherein lower-alkyl is optionally substituted with 1-4 substituents independently selected from the group consisting of fluoro, cyano, hydroxy, lower-alkoxy and fluoro-lower-alkoxy, and wherein aryl is optionally substituted with 1-4 substituents independently selected from the group consisting of halogen, cyano, hydroxy, lower-alkyl, fluoro-lower-alkyl, cyano-lower-alkyl, hydroxy-lower-alkyl, lower-alkyl-C(O)OH, lower-alkyl-C(O)O-lower-alkyl, lower-alkyl-CO—NH 2 , lower-alkyl-CO—N(H, lower-alkyl), lower-alkyl-CO—N(lower-alkyl) 2 , lower-alkyl-N(H, lower-alkyl), lower-alkyl-N(lower-alkyl) 2 , lower-alkoxy-lower-alkyl, CO-lower-alkyl, COOH, COO-lower-alkyl, CONH 2 , CON(H, lower-alkyl), CON(lower-alkyl) 2 , NH 2 , N(H, lower-alkyl), N(lower-alkyl) 2 , lower-alkoxy, fluoro-lower-alkoxy, SO 2 -lower-alkyl, SO 2 —NH 2 , SO 2 —N(H, lower-alkyl), SO 2 —N(lower-alkyl) 2 , cycloalkyl, phenyloxy and phenyl; R 2 is lower-alkyl optionally substituted with 1-4 substituents independently selected from the group consisting of fluoro, cyano, hydroxy, lower-alkoxy and fluoro-lower-alkoxy; R 3 is —O—R 4 or N(R 5 ,R 6 ); R 4 is hydrogen or lower-alkyl; R 5 is hydrogen or lower-alkyl; and R 6 is lower-alkyl or hydroxy-lower-alkyl, or a pharmaceutically acceptable salt thereof.