Patent ID: 8710249

Claim:
A process of producing an aldehyde of formula 1, which comprises the steps of: (i) reacting a pyrone of formula 2 with an aldehyde of formula A-CHO to produce an alcohol of formula 3; (ii) reacting the alcohol of the formula 3 with a dehydrating reagent to produce a triene of formula 4; and (iii) reacting the triene of the formula 4 with an oxidating reagent to produce the aldehyde of the formula 1, wherein: P 1 is hydrogen or a hydroxyl protecting group; R x is halogen or R 2 —X—NR 1 —C(O)—; R 1 is hydrogen or lower alkyl; X is a single bond, a heteroatom group selected from the group consisting of O, S, SO, SO 2 and NH, a loweralkylene or a loweralkylene wherein each alkyl may be intervened by a heteroatom; R 2 is optionally substituted aryl; and A is aryl.