Patent ID: 7465463

Claim:
A method of reducing inflammatory reaction of the eye caused by a severe chemical burn, said method comprising administering to the injured inflamed eye an effective amount of a composition comprising: a pharmaceutically acceptable carrier having a pH between 7 and 9; and about 0.001-25% by weight of microspheres in suspension in said pharmaceutically acceptable carrier, said microspheres having varying diameters in the range of about 0.01 μm to about 200 μm, said microspheres being capable of forming multi-point contacts with a cellular membrane and said microspheres being substantially non-biodegradable during the period of therapy, wherein said microspheres lack the inclusion of any other drug or therapeutic substance, wherein said composition consists of polystyrene microspheres with a size distribution 1-10 micron, with at least 80% of the particles being ranged between 3-7 microns in diameter, in a concentration of 4.5×10 6 ±25% particles/ml, the composition having a pH between 7 and 9, with a zeta potential not higher than −60 mV, an osmolality of 320-354, and a pyrogenicity of not more than 0.5 EU/ml.