Patent ID: 7141590

Claim:
A compound having the structure (I): and optical isomers, diastereomers, enantiomers and pharmaceutically acceptable salts thereof, wherein R 1 is R 5 —SO 2 — and R 5 is selected from alkyl, (CH 2 ) 2 —COOH, aryl, carbocycle, aryl(alkylene), and carbocycle(alkylene) R 2 is hydrogen; R 3 is substituted or unsubstituted aryl or substituted or unsubstituted aryl(alkylene); R 4 is selected from halogen, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted carbocycle aliphatic ring, substituted or unsubstituted amino, or hydroxy, wherein, when R 4 is halogen, it is not para to the N-oxide group; and n is 0 or 1.