Patent ID: 7381840

Claim:
A tetrahydro-naphthalenyl derivative of the formula (I), its tautomeric or stereoisomeric form, or a salt thereof: wherein R 1 represents hydrogen or C 1-6 alkyl; X represents —N(H)Y 1 , —N(H)—C 1-6 alkyleneY 1 , biphenyl or C 1-6 alkyl substituted by biphenyl; wherein said biphenyl is substituted by Z 1 , Z 2 or Z 3 ; Y 1 represents biphenyl substituted by Z 3 , Z 4 or Z 5 ; Z 1 and Z 2 are identical or different and represent hydrogen, halogen, carboxy, nitro, C 1-6 alkyl optionally substituted by cyano or mono-, di-, or tri- halogen, C 1-6 alkoxy optionally substituted by morpholino, or mono-, di-, or tri- halogen, C 1-6 alkylthio, amino, C 1-6 alkylamino, di(C 1-6 alkyl)amino, C 1-6 alkylsulfinyl, C 1-6 alkanoyl, or C 16 alkoxycarbonyl; Z 3 represents hydrogen, halogen, amino, pyrrolidinyl, piperidino, piperazinyl, homopiperidino, C 1-6 alkoxy optionally substituted by mono-, di-, or tri- halogen, or C 1-6 alkyl optionally substituted by mono-, di-, or tri- halogen; Z 4 represents halogen, carboxy, nitro, C 1-6 alkyl optionally substituted by cyano or mono-, di-, or tri- halogen, C 1-6 alkoxy optionally substituted by morpholino, or mono-, di-, or tri- halogen, C 1-6 alkylthio, amino, C 1-6 alkylamino, di(C 1-6 alkyl)amino, C 1-6 alkylsulfinyl, C 1-6 alkanoyl, or C 1-6 alkoxycarbonyl; and Z 5 represents hydrogen, halogen, carboxy, nitro, C 1-6 alkyl optionally substituted by cyano or mono-, di-, or tri- halogen, C 1-6 alkoxy optionally substituted by morpholino, or mono-, di-, or tri- halogen, C 1-6 alkylthio, amino, C 1-6 alkylamino, di(C 1-6 alkyl)amino, C 1-6 alkylsulfinyl, C 1-6 alkanoyl, or C 1-6 alkoxycarbonyl; or Z 4 and Z 5 together with the carbon atom to which they are attached, form a benzene ring.