Patent ID: 7632640

Claim:
A method of detecting a mutant TSPYL gene carrying a 457 — 458 insertion comprising: hybridizing an isolated nucleic acid sequence to a nucleic acid sample wherein said isolated nucleic acid sequence comprises at least 16 contiguous nucleotides of SEQ ID NO. 4 or its complement, spans positions 457 and 458 of the coding region of the TSPYL gene and comprises the 457 — 458ins mutation, under conditions where the nucleic acid sequence hybridizes with a nucleic acid derived from a TSPYL gene having the 457 — 458ins mutation to generate a hybridization complex but not to a nucleic acid derived from a wild type TSPYL gene; and detecting the presence or absence of said hybridization complex, wherein the presence of said hybridization complex indicates the presence of a TSPLY gene carrying a 457 — 458 insertion.