Patent ID: 8691235

Claim:
A bioactive hydroforming luminal liner composition comprising: at least one absorbable crystalline amphiphilic polyether-ester-urethane comprising at least one polyalkylene glycol end-grafted with at least one cyclic monomer selected from the group consisting of ε-caprolactone, p-dioxanone, a lactide, glycolide, 1,5dioxapan-2-one, trimethylene carbonate, and a morpholinedione to form an end-grafted product, wherein polyether-ester is interlinked with a diisocyanate to form a polyether-ester-urethane with an alternating structure (C-[A-B-A])m, wherein C is derived from the diisocyanate, A is the polyester, and B is the polyether, wherein the molar ratio of cyclic monomer to polyalkylene glycol is about 20:1, the molar ratio of polyalkylene glycol to diisocyanate is about 1.5:1, and any unreacted isocyanate group is converted to a urethane group through reaction with an aliphatic alcohol, said polyether-ester-urethane having a molecular weight of at least 10 kDa and a heat of fusion greater than 5 J/g; a liquid derivative of a polyether glycol; and at least one bioactive agent selected from the group consisting of antimicrobial, antiretroviral, antiviral, antiretroviral, anti-inflammatory, antiproliferative, immunosuppressing, antineoplastic, and anesthetic agents.