Patent ID: 7399626

Claim:
An isolated C5-epimerase polypeptide that has glucuronyl C5-epimerase activity that converts D-glucuronic acid to L-iduronic acid, or an enzymatically active fragment thereof that has said C5-epimerase activity, said polypeptide comprising an amino acid sequence at least 97% identical to sequence (n) below and at least 97% identical to at least one of sequences (a) to (m), or (o) below: (a) amino acids 1 to 118 of FIG. 3 (SEQ ID No. 2); (b) amino acids 1 to 119 of FIG. 3 (SEQ ID No. 2); (c) amino acids 1 to 120 of FIG. 3 (SEQ ID No. 2); (d) amino acids 1 to 121 of FIG. 3 (SEQ ID No. 2); (e) amino acids 119 to 618 of FIG. 3 (SEQ ID No. 2); (f) amino acids 120 to 618 of FIG. 3 (SEQ ID No. 2); (g) amino acids 121 to 618 of FIG. 3 (SEQ ID No. 2); (h) amino acids 122 to 618 of FIG. 3 (SEQ ID No. 2); (i) amino acids 34 to 147 of FIG. 3 (SEQ ID No. 2); (j) amino acids 35 to 154 of FIG. 3 (SEQ ID No. 2); (k) amino acids 34 to 154 of FIG. 3 (SEQ ID No. 2); (l) amino acids 1 to 154 of FIG. 3 (SEQ ID No. 2); (m) amino acids 155-618 of FIG. 3 (SEQ ID No. 2); and (n) amino acids 1-618 of FIG. 3 (SEQ ID No. 2); and (o) amino acids 34-618 of FIG. 3 (SEQ ID No. 2).