Patent ID: 7132112

Claim:
A pharmaceutical composition for the administration of diazepam to the nasal mucosal membranes of a mammal in a rate-controlled manner of absorption comprising diazepam and an aqueous vehicle comprising: about 60% by volume of an aliphatic alcohol having from 1 to 5 carbon atoms; about 30% by volume of a glycol selected from the group consisting of propylene glycol, polyethylene glycol 200, polyethylene glycol 300, polyethylene glycol 400, and polyethylene glycol 600; about 1% by weight of a biological surfactant selected from the group consisting of a bile salt selected from the group consisting of sodium cholate, sodium deoxycholate, sodium glycocholate, sodium taurocholate, and sodium ursodeoxycholate and a lecithin selected from the group consisting of lysophosphotidylcholine, dipalmitoylphosphotidylcholin, distearoylphosphotidylcholin, dipalmitoylphosphotidylethanolamine, and dipalmitoylphosphotidylglycerol; and about 10% by volume of water.