Patent ID: 7041819

Claim:
A β-substituted calix[n]pyrrole macrocycle compound consisting of structure I: wherein n is 4, 5, 6, 7, or 8; and when n is 4; p=q=r=s=0, even numbered R substituents are fluoro, chioro, or bromo, odd numbered R substituents are independently as listed in paragraph i) below, and R A –R D are independently substituents as listed in paragraph ii) below; when n is 5; p=1, q=r=s=0, even numbered R substituents are fluoro, chioro, or bromo, odd numbered R substituents are independently as listed in paragraph i) below, and R A –R E are independently substituents as listed in paragraph ii) below; when n is 6; p=q=1; r=s=0, even numbered R substituents are fluoro, chloro, or bromo, odd numbered R substituents are independently as listed in paragraph i) below, and R A –R F are independently substituents as listed in paragraph ii) below; when n is 7; p=q=r=1, s=0, even numbered R substituents are fluoro, chloro, or bromo, odd numbered R substituents are independently as listed in paragraph i) below, and R A –R F are independently substituents as listed in paragraph ii) below; when n is 8; p=q=r=s=1, even numbered R substituents are fluoro, chloro, or bromo, odd numbered R substituents are independently as listed in paragraph i) below, and R A –R H are independently substituents as listed in paragraph ii) below; i) alkyl, alkenyl, alkynyl, aryl, alkylaryl, formyl, acyl, hydroxyalkyl, hydroxyalkoxy, hydroxyalkenyl, hydroxyalkynyl, saccharide, carboxy, carboxyalkyl, carboxyamide, carboxyamidealkyl, alkyl sulfoxide, alkyl sulfone, alkyl sulfide, tetrahydropyran, tetrahydrothiapyran, thioalkyl, haloalkyl, haloalkenyl, haloalkynyl, alkyl ester, a site-directing molecule, a catalytic group, a reporter group, a binding agent, or a couple that is coupled to a site-directing molecule, to a catalytic group, to a reporter group, or to a binding agent; ii) hydrogen, alkyl, aminoalkyl, alkylsulfone, carboxy alkyl, carboxyamidealkyl, phospho alkyl, alkyl sulfoxide, alkyl sulfone, alkyl sulfide, haloalkyl, aryl, N-oxide, dialkylamino, carbamate, or arylsulfonyl.