Patent ID: 7816357

Claim:
The compound of formula I, including all pharmaceutically acceptable salts and stereoisomers thereof, wherein: R 1 is selected from the group consisting of halogen, cyano, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, aryloxy, heteroaryloxy, —NR 8 R 9 , —CO 2 R 8 , —CONR 8 R 9 , —OR 8 , —NR 8 COR 9 , —NR 8 CONR 8 R 9 , —NR 8 CO 2 R 9 , —OCONR 8 R 9 , —NR 8 S(O) p R 9 , —NR 8 S(O) p NR 8 R 9 , —NR 8 S(O) p OR 9 and —OS(O) p NR 8 R 9 ; R 2 is selected from the group consisting of halogen, cyano, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, aryloxy, heteroaryloxy, —NR 8 R 9 , —CO 2 R 8 , —CONR 8 R 9 , —OR 8 , —NR 8 COR 9 , —NR 8 CONR 8 R 9 , —NR 8 CO 2 R 9 , —OCONR 8 R 9 , —NR 8 S(O) p R 9 , —NR 8 S(O) p NR 8 R 9 , —NR 8 S(O) p OR 9 and —OS(O) p NR 8 R 9 ; R 3 is selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heteroaryl and heteroarylalkyl; R 4 is absent when n is a double bond; R 4 is selected from the group consisting of H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heteroaryl and heteroarylalkyl when n is a single bond; R 5 is selected from the group consisting of halogen, —OR 8 , —NR 8 R 9 , —OCONR 8 R 9 , —NHCR 8 , —NHCO 2 R 8 and —NR 8 S(O) p R 9 when m is a single bond, wherein the R 5 group has a molecular weight of less than 200 atomic mass units; R 5 is O when m is a double bond; R 8 and R 9 are independently selected from H, alkyl, arylalkyl, cycloalkyl, heterocyclyl, heterocycloalkyl, aryl, heteroaryl and heteroarylalkyl; m is a single or double bond; n is a single or double bond; when m is a single bond, n is a double bond; when m is a double bond, n is a single bond; and p is an integer of 1 or 2.