Patent ID: 8410277

Claim:
A method for manufacturing a compound represented by the following formula (1): the method comprising reacting a compound represented by the following formula(III): and a compound represented by the following formula (II): in a solvent and in the presence of a palladium catalyst and a base, wherein R 1 represents a hydrogen atom; R 2 represents an amino group that may be protected with a protective group selected from acetyl, pivaloyl and tert-butoxycarbonyl; X represents an oxygen atom and Y represents a nitrogen atom; Q represents a leaving group selected from halogen, a para-toluenesulfonyloxy group, a benzylsulfonyloxy group, methanesulfonyloxy group, a trifluoromethane-sulfonyloxy group, and a chloromethanesulfonyloxy group; the ring A represents a benzene ring; Z represents —CH 2 O—; R represents a hydrogen atom or a C 1-6 alkyl group, if the two R groups are both C 1-6 alkyl groups, they together form a ring; R 3 represents pyridinyl; and R 4 represents a hydrogen atom.