Patent ID: 7361348

Claim:
Immunogenic glycopeptides selected from the group consisting of a 1 ) glycopeptides essentially consisting of a glycosylated T epitope, comprising from 14 to 25 amino acids, among which at least one neutral amino acid is bonded to a disaccharide or to a trisaccharide (glycosidic bond) and at least 15% of said amino acids are prolines, one of the prolines being located in position −1 to −4, relative to the position of said neutral amino acid, which glycopeptides, obtained from a pathogenic microorganism, are: presented by a class II MHC molecule, specifically recognized by CD4+ T lymphocytes induced by immunization with the native glycoprotein from which they are obtained, but are not recognized by the CD4+ T lymphocytes induced by immunization with a non-glycosylated peptide with the same sequence and capable of inducing a proliferation of said CD4+ T lymphocytes which recognize them and the secretion of cytokines by said lymphocytes, and b 1 ) glycopeptides which have a sequence of 15 to 39 amino acids including the sequence of the glycopeptide as defined in a 1 ), excluding the glycopeptide of sequence SEQ ID NO:11.