Patent ID: 7019004

Claim:
A compounds of formula I wherein X and Y independently are O or H, H, R 1 is a group of formula wherein the R a independently are hydrogen, C 1-4 alkyl or a CH 3 COO—CH(CH 3 )OCO-group and Z is a saturated or unsaturated aliphatic C 2-6 hydrocarbonic chain which is (a) optionally interrupted by —O— or —S— and (b) optionally substituted by C 1-4 alkyl or C 1-4 alkoxy groups, R 2 is a group of formula —SO 2 —Ar or —CH 2 —Ar wherein Ar is phenyl or naphthyl optionally mono- or di- substituted by hydroxy, halogen, C 1-4 alkyl, C 1-4 alkoxy, cyano, trifluoromethyl, aminomethyl, dimethylaminocarbonyl, benzimidazolyloxy or morpholinocarbonyl, or by a group of formula wherein Q is CH 2 , O, S or CO, the R b independently are hydrogen, C 1-4 alkyl, C 1-4 alkoxy, amino, halogen, hydroxy, a NH 2 —(CH 2 ) 4 —CH(NH 2 )—COO— group or form together a methylenedioxy, and the R c independently are hydrogen or C 1-4 alkyl, R 3 is hydrogen or C 1-4 alkyl and R 4 is a group of formula wherein R d is hydrogen, halogen, C 1-4 alkyl or C 1-4 alkoxy, and R e is hydrogen, C 1-4 alkyl or benzyl, in free base or acid addition salt form.