Patent ID: 8765669

Claim:
An oligosaccharide chain added GLP-1 peptide having GLP-1 activity, wherein at least two amino acids are each substituted with an oligosaccharide chain added amino acid, wherein the GLP-1 peptide is: (a) GLP-1; or (b) a peptide having the amino acid sequence of GLP-1 with deletion, substitution or addition of 1-3 amino acids, wherein each of the substituted sites is selected from the group consisting of the positions 18, 20, 22, 26, 30, 34, and 36 of GLP-1, and wherein each of said oligosaccharide chains is independently a biantennary complex-type oligosaccharide chain and represented by the following formula: wherein R 1 and R 2 are the same or different and each represents and Ac represents an acetyl group; or a pharmaceutically acceptable salt thereof.