Patent ID: 7132435

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: R 1 is H, halo or (C 1 –C 4 ) alkyl; X is S and Y is —CH 2 —; Z is CO or SO 2 ; R 2 is selected from the group consisting of pyrazolyl, indazolyl, imidazolyl, and benzimidazolyl, each of which may be optionally substituted by one to three moieties independently selected from the group consisting of methyl, N(CH 3 )SO 2 CH 3 , NHSO 2 CH(CH 3 ) 2 , hydroxyl, hydroxymothyl, chioro, fluoro, ethyl, isopropyl, methoxy, OC 2 H 4 OH, C 2 H 4 OH, O(CH 2 ) 3 OH, trifluoromethyl, ethoxy, cyclopropylmethoxy and cyclopentyloxy; and R 3 and R 4 are each independently H, (C 1 –C 4 )alkyl or SO 2 (C 1 –C 4 alkyl).