Patent ID: 6875761

Claim:
A compound represented by the following formula, its pharmaceutically acceptable salt or hydrates thereof wherein, ring A represents a pyridine ring; R 1 represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxyl group; R 2 represents a 1-R 4 -piperazin-4-yl group; R 4 represents a hydrogen atom, a lower alkyl group, a hydroxy lower alkyl group, a halogenated lower alkyl group, a lower cycloalkyl group, an aryl group, an aralkyl group, a 1-piperidyl group, an alkenyl group, a cyano lower alkyl group, a carbamoyl lower alkyl group, a lower acyl group, an aromatic acyl group, a lower alkoxyl carbonyl group, an aryloxycarbonyl group or an aralkyloxycarbonyl group; n represents 0 or an integer of 1 to 6; and B represents an optionally substituted aryl group, an optionally substituted aralkyloxy group, an aryl(hydroxy)alkyl group, an aromatic acyl amino group, an arylsulfonylamino group, a lower alkoxyl arylsulfonylamino group, a hydroxy lower alkoxyl styryl group, a lower alkoxy aryloxy group, a 4-phenylpiperidin-1-yl group, a 4-pyridylpiperidin-1-yl group, an arylalkenyl group, an arylalkynyl group, an aromatic acyl alkynyl group, an optionally N-substituted amino lower alkyl group, an optionally substituted arylamino group, an optionally substituted aralkylamino group or a group selected from the groups represented by the following formulae: wherein p represents 0 or an integer of 1 to 6; R 13 , R 14 , R 16 , R 17 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 25 , R 27 and R 29 independently represent a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, a hydroxy lower alkyl group, a hydroxy lower alkoxy group or tetrahydropyranyl group; R 24 represents a hydrogen atom or a lower alkyl group; R 26 represents a hydrogen atom or a hydroxy lower alkyl group; R 28 represents a hydrogen atom or a lower alkyl group; R 30 represents a hydrogen atom, a lower alkyl group; a lower alkoxy group, a hydroxy lower alkyl group or a hydroxy lower alkoxy group; W represents sulfur atom or oxygen atom; and the bond represented by the following formula: ----- is a single or double bond.