Patent ID: 8029831

Claim:
A method of treating inflammation associated with idiopathic cystitis in animals which comprises administering to an animal suffering signs or symptoms of idiopathic cystitis a composition comprising effective amounts of a thymoquinine-enriched oil extract fraction from the ground seeds of Nigella sativa and at least one component selected from the group consisting of cranberry fruit, cranberry extract, cranberry juice, and methionine, whereby the oil extract fraction is obtained by: (a) extracting the ground Nigella sativa seeds with supercritical carbon dioxide at 120-130 bar at 40° C. for 6 hours to obtain a fraction and collecting the fraction; (b) extracting the ground Nigella sativa seeds with supercritical carbon dioxide at 160-190 bar at 60° C. for 2 hours to obtain a fraction and collecting the fraction; or (c) extracting the ground Nigella sativa seeds with supercritical carbon dioxide at 200 bar at 50° C. for 10 hours to obtain a fraction and collecting the fraction; and continuing administration until said signs or symptoms are reduced or eliminated.