Patent ID: 7157463

Claim:
A compound of formula I: or a pharmaceutically acceptable salts or stereoisomers thereof, wherein G is N; L and L 1 are independently hydrogen or together oxo; is a 5- or 6-membered carbocyclyl wherein the carbocyclyl being saturated, partially saturated or aromatic ring, and the carbocyclyl being optionally substituted with one to three substituents independently selected from R; T is: R is independently: hydrogen, halo, C 1 –C 8 alkyl, C 1 –C 8 alkoxy, C 1 –C 4 haloalkyl, (D)C(O)R 8 , C 1 –C 8 alkyl-N(R 8 ) 2 , (D)OCOR 8 , (D)OC(O)N(R 8 ) 2 , (D)N(R 8 ) 2 , (D)NR 8 C(O)R 8 , (D)NR 8 C(O)OR 8 , (D)NR 8 SO 2 R 8 , or (D)SOR 8 , R 1 is independently: hydrogen, CONH(C 1 –C 8 alkyl), C 1 –C 8 alkyl, (D)phenyl, (D)C 3 –C 7 cycloalkyl or oxo provided that oxo is not attached to the ring carbon adjacent to G; R 3 is aryl; wherein the aryl is optionally substituted with one to three substituents selected from the group consisting of: cyano, halo, C 1 –C 8 alkyl, (D)C 3 –C 7 cycloalkyl, C 1 –C 4 alkoxy, C 1 –C 4 haloalkyl benzyloxy and C 1 –C 4 haloalkyloxy; R 4 is independently: hydrogen, C 1 –C 8 alkyl, C(O)R 8 , C(O)OR 8 , C 3 –C 7 cycloalkyl or (CH 2 ) n O(C 1 –C 8 alkyl), wherein n is 2–8; each R 8 is independently; hydrogen, aryl, wherein aryl being phenyl or naphthyl, C 1 –C 8 alkyl, C 1 –C 8 alkoxy, or (CH 2 ) n C 1 –C 4 haloalkyl, wherein n is 2–8; each R 10 is independently: hydrogen, (C 1 –C 8 )alkyl, C(O)C 1 –C 8 alkyl, aryl, or C 3 –C 7 cycloalkyl; each R 11 is independently: hydrogen, C 1 –C 8 alkyl, (CH 2 ) n N(R 8 ) 2 , wherein n is 2–8; each R 12 is independently: hydrogen, C 1 –C 8 alkyl, (D)C 3 –C 7 cycloalkyl, (D)phenyl C(O)C 1 –C 8 alkyl, C(O)phenyl, SO 2 C 1 –C 8 alkyl or SO 2 -phenyl; D is a bond or —(CH 2 ) n —; n is 0–8; p is 0–4; and q is 0–1.