Patent ID: 7951542

Claim:
A method for treating a human subject having the potential to discontinue treatment with olanzapine due to a treatment-emergent adverse event, comprising: (a) selecting a subject that has been determined to have a SULT4A1-1 haplotype, wherein the SULT4A1 1 haplotype is defined as a haplotype comprising a C allele at rs763120, a combination of an A allele at rs2285162 and a G allele at rs2285167, or the combination of a T allele at rs2285166 and G allele at rs2285167, and treating the subject that has the SULT4A1-1 haplotype with olanzapine, wherein if the human subject comprises the SULT4A1-1 haplotype the subject is more likely to exhibit a propensity to continue treatment with olanzapine; or (b) selecting a subject that has been determined not to have the SULT4A1-1 haplotype and treating the subject that does not have the SULT4A1-1 with an anti-psychotic treatment other than olanzapine, wherein if the subject does not comprise the SULT4A1-1 haplotype the subject is more likely to exhibit a propensity to discontinue treatment due to a treatment-emergent adverse event when treated with olanzapine.