Patent ID: 8871784

Claim:
A method of treatment of psoriasis, ulcerative colitis, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of ischemia-reperfusion injury comprising administering a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein A is selected from the group consisting of benzene, pyrrole, and indole; labels 1 and 2 mark the relevant positions on the A ring; the X atom is nitrogen or carbon; R is a substituting group on the A ring selected from the group consisting of: a group in the 3 (meta) position that is linear or branched C 1 -C 5 -alkyl, linear or branched C 2 -C 5 -alkenyl, linear or branched C 2 -C 5 -alkynyl, or substituted or not-substituted phenyl, linear or branched C 1 -C 5 -hydroxyalkyl, C 2 -C 5 -acyl, substituted or not-substituted benzoyl; and a group in the 4 (para) position that is C 1 -C 5 alkyl, C 2 -C 5 -alkenyl, C 2 -C 5 -alkynyl, C 3 -C 6 -cycloalkyl, C 1 -C 5 -acyloxy, substituted or not-substituted benzoyloxy, C 1 -C 5 -acylamino, substituted or not-substituted benzoylamino, C 1 -C 5 -sulfonyloxy, substituted or not-substituted benzenesulfonyloxy, C 1 -C 5 -alkanesulfonylamino, substituted or not-substituted benzenesulfonylamino, C 1 -C 5 -alkanesulfonylmethyl, substituted or not-substituted benzenesulfonylmethyl, 2-furyl; 3-tetrahydrofuryl; 2-thiophenyl; 2-tetrahydrothiophenyl, C 1 -C 8 -alkanoyl, cycloalkanoyl or arylalkanoyl-C 1 -C 5 -alkylamino; Hy is selected from the group consisting of methyl, ethyl, chlorine, bromine, methoxy and trifluoromethyl; and YR′ is OH.