Patent ID: 8615298

Claim:
A method of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes, comprising: a) pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes; b) determining a weighted electrical dyssynchrony for the first one, the weighted electrical dyssynchrony includes a weighting factor associated with each of the other ones of the left ventricular electrodes based on its distance from the first one; c) pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes; and d) determining a weighted electrical dyssynchrony for the second one, the weighted electrical dyssynchrony includes a weighting factor associated with each of the other ones of the left ventricular electrodes based on its distance from the second one, wherein the weighted electrical dyssynchrony is determined through a weighted electrical dyssynchrony equation (“ED (j, A, D)”) defined as: ED (j,A,D)=Σ i=1 n w(i,j)AT(i,A,D) wherein factor w(i, j) is a distance of a sensing electrode i from a pacing electrode j, n is a total number of left ventricular electrodes, A is atrio-ventricular delay, and D is time delay between pacing pulses in a right ventricle and a left ventricle.