Patent ID: 8124781

Claim:
A process for preparing Compound 1: comprising the steps of: i) providing 2-bromo-3-methylpyridine (compound 2) and 3-(t-butoxycarbonyl)phenylboronic acid (compound 3), ii) cross coupling compound 2 and compound 3 in a biphasic mixture comprising water, a first organic solvent, a first base, and a transition metal catalyst to produce compound 4, iii) oxidizing compound 4 to produce compound 5, iv) adding an amine group to the 6 position of the pyridyl moiety to produce compound 6, v) reacting compound 6 with compound 7, in a second organic solvent in the presence of a second base to produce compound 8, vi) de-esterifying compound 8 in a biphasic mixture comprising water, a third organic solvent, and a first acid to produce compound 9, vii) slurrying or dissolving compound 9 in a solvent for an effective amount of time to produce Compound 1.