Patent ID: 7820705

Claim:
A compound of Formula I: in which R 1 is selected from C 1-6 alkyl, C 3-12 cycloalkyl, C 3-8 heterocycloalkyl, C 6-10 aryl and C 5-10 heteroaryl; wherein any alkyl, aryl, heteroaryl, cycloalkyl and heterocycloalkyl of R 1 is optionally substituted with 1 to 3 radicals independently selected from halo, nitro, cyano, C 1-6 alkyl, C 1-6 alkoxy, halo-substituted-C 1-6 alkyl, halo-substituted-C 1-6 alkoxy, —XC(O)YR 5 and —XYC(O)R 5 ; wherein X is a bond or C 1-4 -alkylene and Y is selected from a bond, O, S, and NR 6 ; and R 5 is selected from C 1-6 alkyl, C 3-12 cycloalkyl, C 3-8 heterocycloalkyl, C 6-10 aryl and C 5-10 heteroaryl; and R 6 is selected from hydrogen, C 1-6 alkyl, C 3-12 cycloalkyl, C 3-8 heterocycloalkyl, C 6-10 aryl and C 5-10 heteroaryl; R 2 is —C(O)NR 4 XOR 5 ; wherein X is a bond or C 1-4 alkylene; R 4 is selected from hydrogen and C 1-6 alkyl; R 5 is selected from C 3-12 cycloalkyl, C 3-8 heterocycloalkyl, C 6-10 aryl and C 5-10 heteroaryl; wherein any alkylene group of R 2 is optionally substituted by halo, C 1-6 alkyl and phenyl; wherein any aryl, heteroaryl, cycloalkyl and heterocycloalkyl of R 2 is substituted with 2 to 3 radicals independently selected from halo, nitro, cyano, methyl, C 1-6 alkoxy, halo-substituted-C 1-6 alkyl and halo-substituted-C 1-6 alkoxy; R 3 is selected from C 3-12 cycloalkyl, C 3-8 heterocycloalkyl, C 6-10 aryl and C 5-10 heteroaryl; wherein any aryl, heteroaryl, cycloalkyl and heterocycloalkyl of R 3 is optionally substituted with 1 to 3 radicals independently selected from halo, nitro, cyano, C 1-6 alkyl, C 1-6 alkoxy, halo-substituted-C 1-6 alkyl, halo-substituted-C 1-6 alkoxy, —XOXC(O)OR 5 , —XC(O)OR 5 wherein X is independently selected from a bond and C 1-4 alkylene; and R 5 is selected from hydrogen and C 1-6 alkyl; or a pharmaceutically acceptable salts thereof.