Patent ID: 8418691

Claim:
A method of compensating for leakage in a ventilation system during delivery of pressure regulated volume control ventilation to a patient, the method performed by the ventilation system, the method comprising: monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system; modeling, by the ventilation system, leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system; estimating a leak-compensated delivered lung volume for at least one breath based on the one or more measurements, the first leakage component and the second leakage component; using the leak-compensated delivered lung volume and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance; and calculating a target pressure to be delivered to the patient for a subsequent breath based on a desired lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance.