Patent ID: 8187593

Claim:
A method for treating or ameliorating a B-cell malignancy or one or more symptoms thereof in a subject, said method comprising administering to a subject in need thereof a therapeutically effective amount of a FcγRIIB-specific antibody or antigen binding fragment thereof; wherein said FcγRIIB-specific antibody comprises a variable domain, wherein said FcγRIIB-specific antibody or fragment thereof is produced from clone 2B6, having ATCC Accession No. PTA-4591, or from clone 3H7, having ATCC Accession No. PTA-4592, and wherein said antibody and said fragment thereof bind FcγRIIB via said variable domain and bind to said FcγRIIB with greater affinity than said antibody or fragment thereof bind FcγRIIA.