Patent ID: 8916690

Claim:
A method for preparing growth-inhibited hydroxyapatite with the steps providing prestructured collagen templates that are denatured or broken up so that fibrillogenesis of the prestructured collagen templates is inhibited, wherein the prestructured collagen templates are capable of diffusion or migration; mineralizing the prestructured collagen templates by; incubating in a first step the prestructured collagen templates in supersaturated solutions containing Ca ions, wherein the Ca ions deposit in a predetermined way on the prestructured collagen templates, and subsequently incubating in a second step the prestructured collagen templates in a phosphate-containing solution to grow epitactic hydroxyapatite crystallites on the prestructured collagen templates, wherein the Ca ions deposited in the first step determine decisively growth inhibition of the hydroxyapatite crystallites, agglomerating the prestructured collagen templates with grown-on hydroxyapatite crystallites by diffusion or migration of the prestructured collagen templates, separating the agglomerates.