Patent ID: 7642272

Claim:
A compound having the formula II, or a pharmaceutically acceptable salt thereof, wherein R 1 , L 1 , M 1 , M 2 , Y and Z are selected from the groups consisting of: R 1 L 1 M 1 -Y —CH(CH 3 ) 2 —CH 2 — —CH(CH 3 ) 2 —CH 2 — —CH(CH 3 ) 2 —CH 2 — —CH(CH 3 ) 2 —CH 2 — —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —CH 2 — —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —N(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 Covalent bond —CH(CH 3 ) 2 —S(O 2 )— —S(O 2 )— —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —S(O 2 )— —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —S(O 2 )— —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —OCH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— —CH(CH 3 ) 2 —S(O 2 )— M 2 -Z Y Z —CF 3 F, —CF 3 —OCF 3 F, —OCF 3 —NH(CH 2 ) 2 OH, —OCF 3 —CH 3 , —OCF 3 F, —OCF 3 H, H F, —OCF 3 H, H F, Cl F, H H, N(CH 2 ) 2 F, H H, —CH(CH 3 ) 2 H, —N(CH 3 ) 2 H, —CH(CH 3 ) 2 H, OH F, F, —CH(CH 3 ) 2 —CH 3 , H, —CH(CH 3 ) 2 H, —OCH 3 H, —CH(CH 3 ) 2 H, —CH(CH 3 ) 2 H, H, H, —CN H, H, —CF 3 H, H F, —OCF 3 F, —OCH 3 H, —OCH 3 F, H, —CH(CH 3 ) 2 H, —OCH(CH 3 ) 2 F, —OCH(CH 3 ) 2 H, —CH(CH 3 ) 2 H, —OCH(CH 3 ) 2 —COOCH 3 , H F, H H, H H, —CF 3 H, and H H.