Patent ID: 7446117

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof in which: X is selected from the group consisting of oxygen and NR 2 ; Y is CH; R 1 is selected from the group consisting of H, C 1-6 alkyl, C 1-2 alkyl substituted by one to five fluorine atoms, C 1-3 alkylOC 1-3 alkyl, C 3-6 alkenyl, C 3-6 alkynyl, C 3-10 cycloalkylC 0-6 alkyl, C 4-7 cycloalkyl substituted by C 1-3 alkyl or C 1-3 alkoxy, C 4-12 bridged cycloalkyl, and A(CR 6 R 7 ) n ; R 2 is selected from the group consisting of H and C 1-6 alkyl; R 3 is selected from the group consisting of C 1-5 alkyl and C 1-2 alkyl substituted by one to five fluorine atoms; R 4 is selected from the group consisting of C 1-6 alkyl, NH 2 and R 9 CONH; R 5 is selected from the group consisting of hydrogen, C 1-3 alkyl, C 1-2 alkyl substituted by one to five fluorine atoms, C 1-3 alkylO 2 C, halogen, cyano, (C 1-3 alkyl) 2 NCO, C 1-3 alkylS and C 1-3 alkylO 2 S; R 6 and R 7 are independently selected from H and C 1-6 alkyl; A is an unsubstituted 6-membered aryl, or a 6-membered aryl substituted by one or more R 8 ; R 8 is selected from the group consisting of halogen, C 1-6 alkyl, C 1-6 alkyl substituted by one more fluorine atoms, C 1-6 alkoxy, C 1-6 alkoxy substituted by one or more F, NH 2 SO 2 and C 1-6 alkylSO 2 ; R 9 is selected from the group consisting of H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylOC 1-6 alkyl, phenyl, HO 2 CC 1-6 alkyl, C 1-6 alkylOCOC 1-6 alkyl, C 1-6 alkylOCO, H 2 NC 1-6 alkyl, C 1-6 alkylOCONHC 1-6 alkyl and C 1-6 alkylCONHC 1-6 alkyl, R 10 is selected from the group consisting of H and halogen; and n is 0 to 4.