Patent ID: 8343993

Claim:
A compound of Formula I: wherein: n is 1 or 2; R 1 is selected from the group consisting of: alkyl, aminoalkyl, dihydroxyalkyl, haloalkyl, hydroxyalkyl, heterocyclylalkylenyl that can be unsubstituted or substituted by one or more C 1-4 alkyl groups; —X—Y—R 4 , and —X—R 5 ; X is straight chain or branched chain C 1-6 alkylene which can be optionally interrupted by one —O— group; Y is —N(R 8 )-Q-; R 4 is selected from the group consisting of straight chain or branched chain alkyl, cycloalkyl, aryl, arylalkylenyl, and heteroaryl that is unsubstituted or substituted by methyl, wherein-the aryl and arylalkylenyl groups can be unsubstituted or substituted by a-substituent selected from the group consisting of alkyl halogen hydroxy and cyano; R 5 is selected from the group consisting of R 6 is ═O; R 7 is propylene; R 8 is selected from the group consisting of hydrogen and alkyl; A is —O—; Q is selected from the group consisting of —C(R 6 )—, —S(O) 2 , —C(R 6 )—N(R 8 )—, and —S(O) 2 —N(R 8 ); and a and b are each 2; or a pharmaceutically acceptable salt thereof.