Patent ID: 8859727

Claim:
A nanoparticle-polypeptide complex, comprising: a) a bioactive polypeptide in association with b) a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the polypeptide, the bioactive polypeptide having an amino acid sequence selected from the group consisting of: (SEQ ID NO: 13) (1) a polypeptide comprising the sequence of KLRRVHKNLPPQGPVKLDHPR; (SEQ ID NO: 14) (2) a polypeptide comprising the sequence of VLRRVHVNLPPQGPVVLDHPR; (SEQ ID NO: 17) (3) a polypeptide comprising the sequence of ETPVTVNGQVRAPLRRVHV; (SEQ ID NO: 1) (4) a polypeptide consisting of the sequence of KLRRVHKNLIPQGIVKLDHPR; or (SEQ ID NO: 16) (5) a polypeptide consisting of the sequence of ETIVTKNGQKRAKLRRVHK.