Patent ID: 7638291

Claim:
A system for use in an immunodiagnostic assay for detecting the presence of topiramate in a sample, the system comprising: an anti-topiramate antibody raised against an antigen, the anti-topiramate antibody including at least one binding domain having affinity, specificity or avidity for at least one topiramate analog and for topiramate, wherein the binding between the antibody and the at least one topiramate analog is at least 50% of at least one of the affinity, the specificity or the avidity of the antibody for topiramate; and the topiramate analog and the antigen having a chemical structure of Formula 1; where L is NH(CH 2 ) 2 NH; X is at least one of the group CH 2 , (CH 2 ) 2 , (CH 2 ) 3 , (CH 2 ) 4 , (CH 2 ) 5 , (CH 2 ) 6 , COCH 2 , CO(CH 2 ) 2 , CO(CH 2 ) 3 , CO(CH 2 ) 4 , CO(CH 2 ) 5 , CO(CH 2 ) 6 , CO(CH 2 ) 2 CONHCH 2 , CO(CH 2 ) 2 CONH(CH 2 ) 2 , or CONH(CH 2 ) 3 ; and Y is a chemical moiety selected from the group consisting of COOH, COO—NHS, COO-tertbutyl, OH,; or Y is a Y 1 -Z where Y 1 is selected from the group consisting of at least one of COO, CO, O, CONH, or NH and Z is an operative group.