Patent ID: 7238658

Claim:
A method of treating a mammal suffering from an agonist disorder, said method comprising administering to said mammal an effective amount of a composition comprising a crystal formed by insulin-like growth factor-1 (IGF-1) of SEQ ID NO: 1 that diffracts x-ray radiation to produce a diffraction pattern representing the three-dimensional structure of the IGF-1, and has approximately the following cell constants a=31.831 Å, b=71.055 Å, c=65.995 Å, and a space group of C2221 1 , and α=β=γ, wherein the IGF-1 is biologically active when resolubilized, wherein said agonist disorder is selected from the group consisting of hyperglycemic disorders, obesity, increased mass-to-lean ratio, heart dysfunctions, wasting, kidney disorders, lung diseases, neurological disorders, neuromuscular disorders, GH- insufficiency, whole body growth disorders, Turner's syndrome, and immunological disorders.