Patent ID: 7569571

Claim:
A compound of formula wherein R 1 is methyl, R 2 is hydrogen, n is 0, 1 or 2, R 3 is cyclopropyl, X 1 is a single bond or alkylene, A, X 2 and D are a pyrazolopyrimidine group of formula III k is an integer from 0 to 4, w is an integer from 0 to 4, R 13 is hydrogen, alkyl, OH or NH 2 , and (CR 9 R 10 ) w E is alkyl, alkoxy, halo, —CH 2 -heterocyclyl, —CONH-cycloalkyl, alkylsulfonyl, alkylthio, alkylsulfonylamino, haloalkyl, aminocarbonyl, pseudohalo or heterocyclyl, or two (CR 9 R 10 ) w E groups, which substitute adjacent atoms on D, together form alkylenedioxy, wherein alkyl is lower alkyl having 1 to 6 carbon atoms, alkylene is lower alkylene having 1 to 6 carbons, haloalkyl is an alkyl group in which one or more of the hydrogen atoms are replaced by halogen cycloalkyl is to a saturated mono- or multicyclic ring system of 3 to 10 carbon atoms, alkoxy is RO—, alkylthio is RS—, R is lower alkyl having 1 to 6 carbon atoms pseudohalo is cyanide, cyanate, thiocyanate, selenocyanate, trifluoromethoxy, or azido and heterocyclyl is a monocyclic or multicyctic non-aromatic ring system of 3 to 10 members where 1 to 3, of the atoms in the ring system is a heteroatom selected from nitrogen, oxygen or sulfur or a pharmaceutically acceptable salt thereof.