Patent ID: 7749528

Claim:
An implantable delivery device for delivery of at least a first therapeutic agent into a target tissue, comprising: a housing, said housing comprising a reservoir with a drug release port for release of at least a first therapeutic agent into a target tissue, said reservoir having at least a first wall that is substantially impermeable to a first therapeutic agent to be placed therein, a sealing base for sealing said release port to a target tissue, wherein when said release port is sealed to a target tissue a first therapeutic agent in said reservoir is substantially prohibited from release by said device other than through said release port into the target tissue, and an attachment mechanism to facilitate sealing of said release port to a target tissue, said attachment mechanism comprising at least one member of the group consisting of a sufficient amount of an adhesive for adhering said sealing base to a target tissue wherein said adhesive is held within at least one cavity or channel within said sealing base, a suture holder for engaging at least one suture operatively attached to the surrounding tissue, and a band for engaging said device with a target tissue, wherein said reservoir comprises a first cavity that is connected to a first refilling port through a first tube.