Patent ID: RE39419

Claim:
A metabolite of (−)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalene-2-ol corresponding to formula I: wherein R 1 is selected from or NH(CH 2 ) 3 COR 6 ; R 5 is selected from H or CH 3 ; R 2 , R 3 , R 4 and R 7 are the same or different and are selected from H and OR 5 ; and R 6 is selected from —OH, or —NHCH 2 COOH, provided that: (a) if R 1 is or —NH(CH 2 ) 3 COOH and (b) R 2 is OH or OCH 3 and R 3 and R 7 are H, or if R 1 is as defined in (a) above and (c) R 2 and R 7 are H and R 3 is OH or OCH 3 , then R 4 is not H; and further provided that when R 2 , R 3 , R 4 and R 7 are H, then R 1 is not or an optical, stereo, regio or configurational isomer or geometric isomer thereof or a tautomer, pharmaceutically acceptable salt, N-oxide, ester, quaternary ammonium salt, or prodrug thereof.