Patent ID: 8263775

Claim:
A compound of Formula (I) wherein: A is pyridyl which may be optionally substituted; R 1 is NHCOR 8 ; X is O; R 8 is selected from hydrogen, optionally substituted alkyl and optionally substituted aryl; R 2 is CN, CO 2 R 9 , C(O)O(O)R 9 , C(O)R 9 or C(O)NR 9 R 10 wherein R 9 and R 10 are independently selected from alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbocyclyl, heterocyclyl, each of which may be optionally substituted, and hydrogen; or R 9 and R 10 , together with the nitrogen atom to which they are attached, form a 3-8-membered ring which may be optionally substituted; R 3 -R 6 are independently selected from hydrogen, halo, nitro, cyano alkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclyl, carbocyclyl, hydroxy, alkoxy, alkenyloxy, alkynyloxy, alkynyloxy, aryloxy, heteroaryloxy, heterocyclyloxy, amino, acyl, acyloxy, carboxy, carboxyester, methylenedioxy, amido, thio, alkylthio, alkenylthio, alkynylthio, arylthio, heteroarylthio, heterocyclylthio, carbocyclylthio, acylthio and azido, each of which may be optionally substituted where appropriate, or any two adjacent R 3 -R 6 , together with the atoms to which they are attached, form a 3-8-membered ring which may be optionally substituted; and Y is hydrogen or C 1-10 alkyl, or a pharmaceutically acceptable salt thereof.