Patent ID: 7358077

Claim:
An electroporation device for electrical treatment of biological cells comprising: a measuring chamber comprising an upper compartment and a lower compartment separated by a fixed carrier element comprising a membrane filter comprising electrically insulating material having a plurality of apertures therethrough, said apertures having a size and density such that one cell extends across 20 to 50 apertures; a pair of electrodes that (a) produce an electrical field across the carrier element, (b) measure the occupation of the carrier element by the cells, when present, and (c) monitor the progress of the electroporation of the cells, when present; wherein each said compartment comprises one electrode of the pair, each electrode being arranged in a planar arrangement extending across the compartment and a measuring and control arrangement comprising a pulse generator for generating electrical field pulses, and an alternating-current impedance measuring device adapted for measuring the alternating-current impedance on the carrier element, wherein the pair of electrodes is connected with the measuring and control arrangement.