Patent ID: 7750027

Claim:
A compound of general formula (II): wherein W is chloro or fluoro; R 1 is phenyl optionally substituted with one or more substituents, selected from halo, —CN, —C 1 -C 6 alkyl, —SOR 3 , —SO 2 R 3 , —SO 2 N(R 2 ) 2 , —N(R 2 ) 2 , —NR 2 C(O)R 3 , —CO 2 R 2 , —CONR 2 R 3 , —NO 2 , —OR 2 , —SR 2 , —O(CH 2 ) p OR 2 , or —O(CH 2 ) p O(CH 2 ) q OR 2 wherein each R 2 is independently hydrogen, C 1 -C 6 alkyl, —C 3 -C 8 cycloalkyl, aryl or heteroaryl; each R 3 is independently, C 1 -C 6 alkyl, —C 3 -C 8 cycloalkyl, aryl or heteroaryl; p and q are each independently an integer from 1 to 3; and R 4 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkyl substituted with aryl, aryl, (CH 2 ) m OC(═O)C 1 -C 6 alkyl, ((CH 2 ) m O) n CH 2 CH 2 X, (CH 2 ) m N(R 5 ) 2 or CH((CH 2 ) m O(C═O)R 6 ) 2 ; m is 1 or 2; n is 1-4; X is OR 5 or N(R 5 ) 2 ; R 5 is hydrogen or methyl; and R 6 is C 1 -C 18 alkyl; or a pharmaceutically acceptable salt thereof.