Patent ID: 8835444

Claim:
A compound of formula I; in which R 1 is a group: wherein X 1 is haloalkyl C1 to 10; X 2 is halogen; R 4 together with R 5 and the nitrogen to which they are attached forms a group of formula III; R 5 together with R 4 and the nitrogen to which they are attached forms a group of formula III; X 5 is O or —CH 2 —; X 6 is O or —CH 2 —; R 12 is hydrogen, alkyl C1 to 6, alkoxy C1 to 6, hydroxyalkyl C1 to 6, —CO 2 R 11 or phenyl optionally substituted by fluoro; R11 is alkyl C1 to 6; R 13 is hydrogen, alkyl C1 to 6 or chloro; R 14 is hydrogen, alkyl C1 to 6, methoxy, hydroxyalkyl C1 to 6, ethoxycarbonyl, pyridyl, benzo[1,3]dioxo-5-yl or phenyl, optionally substituted by fluoro, alkoxy C1 to 6; R 15 is hydrogen or methyl; R 16 , R 17 , R 18 , R 19 , R 20 , which may be the same or different, are each hydrogen or alkyl C1 to 6; and stereoisomers thereof; in free form or in salt form; provided that the compound of formula I is not: trans-2-chloro-N-[4-(3,5-dimethyl-pyrazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide; trans-2-chloro-N-[4-(3,5-di-(d3)-methyl-pyrazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide; trans-2-chloro-N-[4-(5-methyl-pyrazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide; trans-2-chloro-N-[4-(3-methyl-pyrazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide; trans-2-chloro-N-{4-[3-(4-methoxy-phenyl)-pyrazol-1-ylmethyl]-cyclohexyl}-5-trifluoromethyl-benzamide; 2-chloro-N-[4-(4-chloro-3,5-dimethyl-pyrazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide; 2-chloro-5-trifluoromethyl-N-[4-(3,4,5-trimethyl-pyrazol-1-ylmethyl)-cyclohexyl]-benzamide; 2-chloro-N-[4-(3-phenyl-pyrazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide.