Patent ID: 8828996

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein, independently for each occurrence: R 1 is C1-C6 alkyl, C1-C6 fluoroalkyl, C3-C8 cycloalkyl, halo, NR 8 SO 2 R 8 , SO 2 R 8 , SR 8 , SOR 8 , NR 8 COR 8 , NR8CO 2 R 8 , CN, CON(R 8 ) 2 , SO 2 N(R 8 ) 2 , CF 3 , optionally substituted heterocycloalkyl, phenyl, heteroaryl, or a straight chain, branched, or cyclic-(C3-C8)—R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2 , N, CF 2 , or NR 8 ; R 2 is H, C1-C6 alkyl, C1-C6 fluoroalkyl, an optionally substituted cycloalkyl, aryl, heteroaryl, or heterocycloalkyl, COR 8 , CO 2 R 8 , CON(R 8 ) 2 , CF 3 , CHF 2 , or a straight chain, branched, or cyclic-(C3-C8)—R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2 , N, CF 2 , or NR 8 ; R 3 is C1-C6 alkyl or halo; R 8 is H, C1-C6 alkyl, or C3-C8 cycloalkyl, a straight chain, branched, or cyclic (C3-C8)—R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2 , N, CF 2 , or NR, or 2 R 8 taken together with the atoms to which they are attached form a ring; R 9 is H, CF 3 , CHF 2 , CH 2 F, CO 2 R, OH, optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl, heterocycloalkyl, N(R) 2 , NRCOR, CON(R) 2 , CN, or SO 2 R; R is H, C1-C6 alkyl, optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl, or heterocycloalkyl; A is an aryl, heteroaryl or heterocyclic in which each is optionally substituted with C1-C6 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkoxy , C1-C6 alkoxy, halo, CN, OH, OR 8 , N(R 8 ) 2 , NR 8 SO 2 R 8 , SO 2 R 8 , SOR 8 , SR 8 , CO 2 R 8 , NR 8 COR 8 , NR 8 CO 2 R 8 CON(R 8 ) 2 , SO 2 N(R 8 ) 2 , CHF 2 , CF 3 , OCF 3 , OCHF 2 , R 9 , heterocycloalkyl, heterocycloalkoxy, aryl, heteroaryl, or a straight chain, branched, or cyclic (C3-C8)—R 9 wherein up to three CH 2 units may be replaced with O, CO, S, SO, SO 2 , N, CF 2 , or NR 8 ; n is an integer from 0 to 4 inclusive; and o is an integer from 0 to 4 inclusive.