Patent ID: 7691645

Claim:
A method for producing and recovering a modified sample, said method comprising: removing at least a first protein and a second protein from a sample, said removing step comprising contacting said sample with an affinity binding composition comprising a first solid phase matrix with a first receptor immobilized thereon capable of specific binding to said first protein but not said second protein and a second solid phase matrix with a second receptor immobilized thereon capable of specific binding to said second protein but not said first protein, wherein each said solid phase matrix is a plurality of particles and said first and second solid phase matrices are present as a mixture in said binding composition; so that when said sample is contacted with said affinity binding composition, said first protein present in said sample binds to said first receptor present on said first solid phase matrix such that said first protein is removed from said sample and said second protein present in said sample binds to said second receptor present on said second solid phase matrix such that said second protein is removed from said sample and said modified sample is thereby produced, wherein said modified sample is not bound by a solid phase matrix; and recovering said modified sample.