Patent ID: 7776909

Claim:
A method of treatment of psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the treatment of damages caused by reperfusion after ischemia comprising administering a compound of formula (Ia): or a pharmaceutically acceptable salt thereof, wherein A is selected from benzene, naphthalene, pyridine, pyrimidine, pyrrole, imidazole, furane, thiophene, indole and 7-aza-indole and labels 1 and 2 mark the relevant positions on the A ring; the X atom is selected from N (nitrogen) and C (carbon); R is a substituting group on the A ring selected from: a group in the 3 position selected from a linear or branched C 1 -C 5 alkyl, C 2 -C 5 -alkenyl or C 2 -C 5 -alkynyl group, substituted or not-substituted phenyl, linear or branched C 1 -C 5 hydroxyalkyl, C 2 -C 5 -acyl, substituted or not-substituted benzoyl; a group in the 4 position selected from C 1 -C 5 alkyl, C 2 -C 5 -alkenyl or C 2 -C 5 -alkynyl group, C 3 -C 6 -cycloalkyl, C 1 -C 5 -acyloxy, substituted or not-substituted benzoyloxy, C 1 -C 5 -acylamino, substituted or not-substituted benzoylamino, C 1 -C 5 -sulfonyloxy, substituted or not-substituted benzenesulfonyloxy, C 1 -C 5 -alkanesulfonylamino, substituted or not-substituted benzenesulfonylamino, C 1 -C 5 -alkanesulfonylmethyl, substituted or not-substituted benzenesulfonylmethyl, 2-furyl; 3-tetrahydrofuryl; 2 thiophenyl; 2-tetrahydrothiophenyl groups or a C 1 -C 8 -alkanoyl, cycloalkanoyl or arylalkanoyl-C 1 -C 5 -alkylamino group; Hy is selected from the group consisting of methyl, ethyl, chlorine, bromine, methoxy and trifluoromethyl Rd is C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, or C 2 -C 6 -alkenyl.