Patent ID: 7368438

Claim:
A method of treating diseases or conditions associated with increased platelet aggregation comprising: administering to a subject a pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula III, or a pharmaceutically acceptable hydrate, solvate or salt thereof, wherein said amount is effective to inhibit platelet aggregation, wherein R is H, or saturated or unsaturated C 1-8 alkyl; R a and R c is H; R b is selected from the group consisting of: saturated or unsaturated C 1-8 alkyl, saturated or unsaturated C 3-7 cycloalkyl, aralkyl, and aryl; where all rings or chains optionally bear one or more desired substituents; R d and R d′ are independently selected from the group consisting of: H, saturated or unsaturated C 1-8 alkyl, saturated or unsaturated C 3-7 cycloalkyl, aralkyl, aryl; R e is absent; R f and R g are independently selected from the group consisting of: H, halogen, saturated or unsaturated C 1-8 alkyl, saturated or unsaturated C 3-7 cycloalkyl, aryl, aralkyl; G is O; J is carbon: X 1 is selected from the group consisting of: N and C-M; and M is selected from the group consisting of: —H, halogen, —CF 3 , saturated or unsaturated C 1-8 alkyl, saturated or unsaturated C 3-7 cycloalkyl, —OH, saturated or unsaturated C 1-6 alkoxy, amino, —N-substituted amino, and N,N-disubstituted amino.