Patent ID: 8263591

Claim:
A compound according to formula A: wherein: W is oxygen; X, Y and Z are independently selected from the group consisting of —N, or —CR, wherein: R is H, —Br, —Cl, —F, —CN, —NO 2 , —OR 1 , —SR 1 , —NR 1 2 , —C 1 -C 6 branched or un-branched alkyl, which may be un-substituted or substituted, wherein: R 1 is H, —C 1 -C 6 branched or un-branched alkyl which, may be un-substituted or substituted, n is 0, 1, 2, 3, 4, 5 m is 0, 1, 2, 3, 4, 5 p is 1, 2, 3, 4, 5 R 2 and R 3 are each independently selected from H, a halogen (preferably F), —CN, —NO 2 , —OR 1 , —SR 1 , —NR 1 2 , CF 3 , OH, C═O, a —C 1 -C 6 branched or un-branched alkyl, which may be un-substituted or substituted, a —C 2 -C 6 branched or un-branched alkenyl, which may be un-substituted or substituted, a —C 2 -C 6 branched or un-branched alkynyl, which may be un-substituted or substituted, a —C 3 -C 7 cycloalkyl which may be un-substituted or substituted, an aryl which may be un-substituted or substituted, a heterocycle which may be un-substituted or substituted, a carboxyalkyl which may be un-substituted or substituted, a carboxyaryl which may be un-substituted or substituted, a carboxyheteroaryl which may be un-substituted or substituted, a sulfonylalkyl which may be un-substituted or substituted, a sulfonylaryl which may be un-substituted or substituted or a sulfonylheteroaryl which may be un-substituted or substituted, E and F are each independently selected from CH 2 m, CR 2 R 3 , A, CH 2 A, CR 2 ═CR 3 or are absent, with the proviso that E and F are not both absent; G is CR 2 R 3 , A, CH 2 A, CR 2 ═CR 3 , CH 2 C═O, CH 2 CR 2 R 3 , or absent, A is O, S, SO, SO 2 , C═O or CR 2 R 3 ; or a pharmaceutically acceptable salt thereof.