Patent ID: 7910740

Claim:
A compound of formula I wherein hetaryl I is hetaryl II is R 1 is hydrogen, lower alkoxy or cyano; R 2 and R 3 are each independently hydrogen, lower alkyl, lower alkyl substituted by halogen, CHO, —CRR′-phenyl, wherein the phenyl rings are unsubstituted or substituted by one or more halogen, cyano, lower alkyl, lower alkyl substituted by halogen, lower alkoxy substituted by halogen or lower alkoxy, —C(O)O-lower alkyl, —CH 2 —C(O)O-lower alkyl, —CH 2 —C(O)-piperidin-1-yl, —CH 2 —C(O)NH-lower alkyl, —CH 2 —C(O)NH-phenyl optionally substituted by halogen, —CHR—NHC(O)O-lower alkyl, —CHR—NH 2 , —CHR—NH—CH 2 -phenyl optionally substituted by halogen, —CHR—NH—(CH 2 ) 2 -phenyl optionally substituted by halogen, —CHR—NH—phenyl optionally substituted by halogen, —CHR—NH—cycloalkyl, —CHR—NHC(O)—CH 2 -phenyl optionally substituted by halogen, —CHR—NHC(O)—CH 2 O-lower alkyl, —CHR—NHC(O)-lower alkyl, —CHR—NHC(O)O-lower alkyl substituted by halogen, —CHR—NHC(O)-phenyl optionally substituted by halogen, —CHR—NHCH 2 CH 2 O-lower alkyl, —CHR—NH—S(O) 2 -phenyl optionally substituted by halogen or lower alkyl, —CHR—NH—S(O) 2 —CH 2 -phenyl optionally substituted by halogen, —CHR—NH—S(O) 2 -lower alkyl, —CH 2 -piperidin-1-yl, —CH 2 -morpholinyl or -indole-2-carboxylic acid-(3,4-difluoro-phenyl)amide; R and R′ are each independently hydrogen, lower alkyl, benzyl or hydroxy; R 4 is hydrogen, —C(O)O-lower alkyl, —C(O)-phenyl optionally substituted by halogen, —C(O)-lower alkyl substituted by halogen, —C(O)-lower alkyl, —S(O) 2 -phenyl optionally substituted by halogen, —S(O) 2 -lower alkyl, —S(O) 2 —CH 2 - phenyl, -benzyl optionally substituted by halogen, —CH 2 —CH 2 -phenyl, —C(O)—CH 2 -phenyl optionally substituted by halogen or —C(O)—CH 2 -lower alkoxy; R 5 is halogen, lower alkyl substituted by hydroxy, or is lower alkyl; and n is 0 or 1; or a pharmaceutically active acid addition salt thereof.