Patent ID: 7202249

Claim:
A compound of formula (I) including enantiomers, diastereomers, tautomers, and pharmaceutically acceptable salts, thereof wherein: A, B, D, and E, are selected from N or, and exactly one of A, B, D, and E is N; M is CH or N; Z is C(═O)GR 2 or C(H) 2 GR 2 ; G is O or NH or none, or when Z is C(═O)GR 2 , G can also be alkylene; n is 0–4; R 1 is selected from halogen, —CN, —CF 3 , substituted alkyl, aryl, and heteroaryl; R 2 is a 5- to 6-membered heterocycloalkyl containing one N; and R 4 and R 5 are H; or R 4 and R 5 may be taken together with the atoms to which they are attached to form a ring wherein the ring is selected from piperidine and piperazine; and R 10 is selected from H, alkyl, substituted alkyl, alkenyl, and substituted alkenyl.