Patent ID: 6864259

Claim:
A compound of Formula I: or a pharmaceutically acceptable salt thereof wherein: R 1 is H, C 1 -C 7 alkyl and substituted alkyl, C 2 -C 7 alkenyl and substituted alkenyl, C 2 -C 7 alkynyl and substituted alkynyl, C 3 -C 7 cycloalkyl and substituted cycloalkyl, aryl and substituted aryl, heterocyclic and substituted heterocyclic, or heteroaryl and substituted heteroaryl; R 2 is H, C 1 -C 7 alkyl and substituted alkyl, C 2 -C 7 alkenyl and substituted alkenyl, C 2 -C 7 alkynyl and substituted alkynyl, C 3 -C 7 cycloalkyl and substituted cycloalkyl, aryl and substituted aryl, heterocyclic and substituted heterocyclic, heteroaryl and substituted heteroaryl, halo, NO 2 , NO, CN, OR a , wherein R a is H, C 1 -C 7 alkyl and substituted alkyl, C 2 -C 7 alkenyl and substituted alkenyl, C 3 -C 7 cycloalkyl and substituted cycloalkyl, aryl and substituted aryl, heteroaryl and substituted heteroaryl, heterocycloalkyl and substituted heterocycloalkyl, wherein R b is H, C 1 -C 7 alkyl and substituted alkyl, C 2 -C 7 alkenyl and substituted alkenyl, C 3 -C 7 cycloalkyl and substituted cycloalkyl, aryl and substituted aryl, heteroaryl and substituted heteroaryl, heterocycloalkyl and substituted heterocycloalkyl; wherein R c and R d are independantly H, C 1 -C 7 alkyl and substituted alkyl, C 2 -C 7 alkenyl and substituted alkenyl, C 3 -C 7 cycloalkyl and substituted cycloalkyl, aryl and substituted aryl, heteroaryl and substituted heteroaryl, heterocycloalkyl and substituted heterocycloalkyl; NR e R f , wherein R e and R f are each independently H, C 1 -C 7 alkyl and substituted alkyl, C 2 -C 7 alkenyl and substituted alkenyl, C 2 -C 7 alkynyl and substituted alkynyl, C 3 -C 7 cycloalkyl and substituted cycloalkyl, C 5 -C 8 cycloalkenyl and substituted cycloalkenyl, aryl and substituted aryl, or wherein R c and R d are defined as above; aryl and substituted aryl, heteroaryl and substituted heteroaryl, heterocycloalkyl and substituted heterocycloalkyl, or R e and R f are taken together with the nitrogen to which they are attached form a 4, 5, 6, 7, or 8 membered ring having from 0 to 3 heteroatoms selected from N, O, and S, wherein said ring is optionally substituted by one or more substituents; R 3 , R 4 , and R 6 independently are H, OH, (O) n C 1 -C 7 alkyl and substituted alkyl, (O) n C 2 -C 7 alkenyl and substituted alkenyl, (O) n C 2 -C 7 alkynyl and substituted alkynyl, wherein n is 0 or 1, halo, NO 2 , CN, NR e R f , wherein R e and R f are defined as above; R 5 is C 2 -C 7 alkenyl and substituted alkenyl, C 2 -C 7 alkynyl and substituted alkynyl, OR a , wherein R a is defined as above, wherein R c and R d are defined as above; halo, NO 2 , CN, NR e R f , wherein R e and R f are defined as above; aryl or fused aryl, heterocyclic or fused heterocyclic, heteroaryl or fused heteroaryl, or bicyclic heterocyclic or spiro heterocyclic, wherein fused aryl, fused heterocyclic, fused heteroaryl, bicyclic heterocyclic, or spiro heterocyclic can be substituted.