Patent ID: 8492407

Claim:
A compound having the formula IId: where: X − is an anion of a pharmaceutically acceptable acid; R 3 is selected from H and —C 0-1 alkylene-OH; or R 3 can form a double bond with the carbon atom on the cyclopentyl group; Z is selected from a bond, —O—, and —C(O)—; wherein the cyclopentyl group is optionally substituted with 1 to 5 R groups independently selected from —C 1-4 alkyl, —C 2-4 alkenyl, —C 2-4 alkynyl, —C 3-6 cycloalkyl, cyano, halo, —OR a , —SR a , —S(O)R a , —S(O) 2 R a , and —NR b R c ; where each R a is independently selected from H, —C 1-4 alkyl, —C 2-4 alkenyl, —C 2-4 alkynyl, and —C 3-6 cycloalkyl; and each R b and R c is independently selected from H, —C 1-4 alkyl, —C 2-4 alkenyl, —C 2-4 alkynyl, and —C 3-6 cycloalkyl; wherein R Q is selected from halo, —C 1-4 alkyl, —C 0-4 alkylene-OH, cyano, —C 0-2 alkylene-COOH, —C(O)O—C 1-4 alkyl, —O—C 1-4 alkyl, and —N + (O)O; wherein each alkyl, alkylene, alkenyl, alkenylene, alkynyl, and cycloalkyl group in R, R 3 , and R Q , is optionally substituted with 1 to 5 fluoro atoms; and each —CH 2 — group in —(CH 2 ) 1-4 — is optionally substituted with 1 or 2 substituents independently selected from —C 1-2 alkyl, —OH, fluoro, and phenyl; or a pharmaceutically acceptable salt thereof.