Patent ID: 7238774

Claim:
A compound of formula (I) wherein R 1 represents a) a carboxy-C 1-6 -alkyl-, b) a C 1-6 -alkyl-O—CO—C 1-6 -alkyl-, c) a C 3-8 -cycloalkyl- or C 3-8 -cycloalkyl-C 1-3 -alkyl-, d) a heterocyclyl-, e) a aryl-, or a aryl-C 1-3 -alkyl-, or f) a heteroaryl-group wherein each of said groups may be optionally substituted by one or more substituents independently selected from the group consisting of C 1-6 -alkyl-, aryl-CO—, C 1-6 -alkyl-O—, C 1-6 -alkyl-O—CO—, C 1-6 -alkyl-CO—, C 1-6 -alkyl-CO—NR 8 —, halogen-, carboxy-, hydroxy-, nitro-, oxo- or (R 8 ) 2 N—SO 2 -groups, R 2 represents (a) a C 1-6 -alkyl- or C 2-6 -alkenyl-group, optionally substituted by one or more substituents independently selected from the group consisting of heteroaryl-, phenyl-, C 3-8 -cycloalkyl- or heterocyclyl-groups, wherein the phenyl group may be optionally substituted by one or more substituents independently selected from the group consisting of C 1-3 -alkyl-groups which may be optionally substituted with a hydroxyl-group, cyano-, C 1-3 -alkynyl-, halogen, hydroxy-, carboxy-, nitro-, (R 8 ) 2 N—CO—, (R 8 ) 2 N— or C 1-3 -alkyl-N(R 8 )C(O)N(R 8 )-groups, or (b) a bicyclic carbocyclic ring, optionally substituted by one or more substituents independently selected from the group consisting of C 1-3 -alkyl-, halogen, hydroxy-, carboxy-, nitro-, (R 8 ) 2 N—CO— or (R 8 ) 2 N-groups, R 3 represents a C 1-6 -alkyl-, C 1-6 -alkylthio-C 1-3 -alkyl-, C 2-6 -alkenyl, C 2-6 -alkinyl or a C 3-8 -cycloalkyl-C 1-3 -alkyl-group, optionally substituted by one or more substituents independently selected from the group consisting of fluor or cyano-, R 4 represents a C 1-6 -alkyl-, C 2-6 -alkenyl-, C 3-8 -cycloalkyl-C 1-3 -alkyl-, aryl-, aryl-C 1-3 -alkyl- or a heteroaryl-C 1-3 -alkyl-group, wherein each of said groups may be optionally substituted by one or more substituents independently selected from the group consisting of C 1-6 -alkyl-, C 1-6 -alkyl-O—, (R 8 ) 2 N—CO—, aryl-C 1-3 -alkyl-O— or hydroxy-groups, R 5 represents a C 1-6 -alkyl-, C 3-8 -cycloalkyl-C 1-3 -alkyl- or a aryl-C 1-3 -alkyl-group, wherein each of said groups may be optionally substituted by one or more substituents independently selected from C 1-6 -alkyl-S— or a halogen atom, R 6 and R 7 each independently represent hydrogen or a halogen atom, R 8 represents hydrogen or a C 1-6 -alkyl-group, or a pharmaceutically acceptable salt or solvate thereof.