Patent ID: 8871212

Claim:
A polypeptide comprising a first, second and third Aβ polypeptide domain, said first Aβ polypeptide domain being N-terminal to said second Aβ polypeptide domain, and said second Aβ polypeptide domain being N-terminal to said third Aβ polypeptide domain, wherein: (A) said Aβ polypeptide domains each comprise amino acid residues 672-683 of SEQ ID NO:2 (Aβ(1-12)); (B) said first and second Aβ polypeptide domains are separated from one another by an intervening polypeptide comprising a first tetanus toxoid epitope domain; and (C) said second and third Aβ polypeptide domains are separated from one another by an intervening polypeptide comprising a second tetanus toxoid epitope domain; wherein said first and second tetanus toxoid domains are different and are selected from the group consisting of a P30 tetanus toxoid epitope domain (SEQ ID NO:6) and a P2 tetanus toxoid epitope domain (SEQ ID NO:4).