Patent ID: 7438911

Claim:
An antibody or an antibody fragment thereof, which (i) specifically binds to IGF-I and IGF-II to inhibit both human IGF-I and human IGF-II, and (ii) binds to both human IGF-I and human IGF-II with almost equivalent strength of affinity and with a binding constant of 5×10 9 M −1 or more measured with a biosensor BIACORE™, the CDR1, CDR2 and CDR3 of the VH chain of said antibody or said antibody fragment thereof comprising SEQ ID NOS:5, 6 and 7 respectively, and/or CDR1, CDR2 and CDR3 of the VL chain of said antibody or said antibody fragment comprising SEQ ID NOS: 8, 9 and 10 respectively.