Patent ID: 7179489

Claim:
A process for preparing a pharmaceutical composition comprising, in admixture, an active ingredient which is micronised formoterol or an enantiomer thereof, optionally in the form of a salt or solvate or a solvate of a salt, and a micronised carrier/diluent, which process comprises (a) preparing a mixture of micronised active ingredient and carrier/diluent, followed by (b) addition of further pre-micronised carrier/diluent which is mixed in at a pressure of less than 2 bar, and (c) either subjecting the mixture to agglomeration and spheronisation, or adding coarse carrier/diluent. wherein the pharmaceutical composition exhibits a storage stability such that the decomposition of formoterol on the composition will be less than 10% (w/w) when stored in open dishes at 40° C. and 75% relative humidity for 6 months when the content of formoterol is less than about 1.0% (w/w) in the composition.