Patent ID: 8524870

Claim:
An isolated antibody or antigen-binding fragment thereof that specifically binds to loop 9 in domain 2 of human platelet glycoprotein VI (GPVI), wherein said antibody or antigen-binding fragment thereof comprises a variable heavy chain (VH) with 3 complementarity determining regions (CDR) and a variable light chain (VL) with 3 complementarity determining regions (CDR), comprising the following VH CDR1, VH CDR2, VH CDR3, VL CDR1, VL CDR2, and VL CDR3, respectively of: (i) SEQ ID NOs: 335, 336, 337, 377, 378 and 379; (ii) SEQ ID NOs: 344, 345, 346, 386, 387 and 388; (iii) SEQ ID NOs: 347, 348, 349, 389, 390 and 391; (iv) SEQ ID NOs: 356, 357, 358, 398, 399, and 400; or (v) SEQ ID NOs: 371, 372, 373, 413, 414, 415.