Patent ID: 7105570

Claim:
A method for preventing or treating a disorder caused or promoted by an oxidative stress mediated by a transcriptional regulatory factor NF-κB or AP-1, which method comprises applying onto the skin of a subject in need thereof a cosmetic composition or a dermatologic preparation for external use comprising, as an effective ingredient, at least one compound represented by formula (III) or a salt thereof: wherein R 10 and R 12 represent an aminocarbonyl group, an acyl group having 2–22 carbon atoms, an alkyl group having 1–22 carbon atoms, a hydroxyalkyl group having 1–22 carbon atoms or a 3-alkoxy-2-hydroxypropyl group whose alkoxyl group has 1–22 carbon atoms; each W and each X represents, each independently, a hydrogen atom or an alkyl group having 1–6 carbon atoms, and k and l stand, each independently, for an integer of 0 to 5, while R 11 and R 13 represent a hydrogen atom, an alkyl group having 1–22 carbon atoms, a hydroxyalkyl group having 1–22 carbon atoms or a 3-alkoxy-2-hydroxypropyl group whose alkoxyl group has 1–22 carbon atoms, with the proviso that when R 10 and R 12 represent an acyl group having 2 or 4 carbon atoms, and k and l are each 1, R 11 and R 13 represent an alkyl group having 1–22 carbon atoms, a hydroxyalkyl group having 1–22 carbon atoms or a 3-alkoxy-2-hydroxypropyl group whose alkoxyl group has 1–22 carbon atoms; wherein said disorder is selected from the group consisting of skin aging, wrinkles, skin inflammation, sunburn, xeroderma pigmentosum or solar urticaria, photoallergy, optical immunosuppression, rough skin caused by injury, rough skin caused by chaps, rough skin caused by cleft, atopic dermatitis, contact dermatitis, and psoriasis vulgaris.