Patent ID: 8088884

Claim:
An activated polyoxazoline-2 (POZ-2) derivative of the general structure Wherein POZ a is a polyoxazoline of formula —[N(COR 2 )CH 2 CH 2 ] n —; POZ b is a polyoxazoline of formula —[N(COR 2 )CH 2 CH 2 ] x —; L(I), L(II) and L(III) are linking groups; Br is a branching moiety that is linked with or without a linking group to POZ a , POZ b and is selected from the group consisting of a nitrogen atom, a substituted or unsubstituted aryl group or a carbon atom, provided that when Br is a carbon atom, at least one of c or d is 1 and the corresponding linking group contains a substituted or unsubstituted aryl group; X is a functional group which is capable of forming a linkage with a target molecule or being converted to a group that is capable of forming a linkage with a target molecule; A is a non-reactive group; R 1 is independently selected for each of POZ a and POZ b from hydrogen, alkyl, substituted alkyl, aralkyl, or substituted aralkyl group; R 2 is independently selected for each repeating unit of POZ from an unsubstituted or substituted alkyl, alkenyl, alkyl, aralkyl or aryl group; c, d and e are independently selected from 1 or zero; f is zero when Br is a nitrogen atom or substituted or unsubstituted aryl group and is 1 when Br is a carbon atom; and n and x are independently selected for each of POZ a and POZ b from 3 to 1000.