Patent ID: 7847074

Claim:
Process for preparing the compounds of general formula I, wherein R 1 denotes hydrogen, or C 1-4 -alkyl, C 3-7 -cycloalkyl, tetrahydrofuranyl, or tetrahydropyranyl, which may be substituted with one to four substituents L2, or an aryl-group or a 5- or 6-membered monocyclic heteroaryl-group or a 8-, 9- or 10-membered bicyclic heteroaryl-group wherein said heteroaryl-groups have 1 to 4 heteroatoms independently selected from the group consisting of N, O and S; and wherein said heteroaryl-group may possess 1 or 2 carbonyl groups as part of the mono- or bicyclic aromatic ring-system; and wherein an N-atom of the heteroaryl ring-system may be oxidized to form the corresponding N-oxide; and wherein one or more methine groups in said aryl- and heteroaryl-group may be substituted independently of one another with a substituent L1; and wherein one or more imino-groups in said heteroaryl-group may be substituted independently of one another with a substituent R N ; and R 2 denotes chlorine or methyl; and R 3 denotes hydrogen; R N independently of one another are selected from among C 1-3 -alkyl; and L1 independently of one another are selected from among fluorine, chlorine, bromine, C 1-3 -alkyl, C 1-4 -alkoxy and nitro; L2 independently of one another are selected from among fluorine, chlorine, hydroxy, hydroxyl-C 1-4 -alkyl, C 1-4 -alkoxy, trifluoromethoxy, C 1-4 -alkoxy-C 1-4 -alkyl, cyano, C 1-4 -alkyl, trifluoromethyl, amino, C 1-4 -alkyl-carbonylamino, C 1-3 -alkyl-amino and di(C 1-3 -alkyl)-amino; and while by the aryl groups mentioned in the definition of the above groups are meant phenyl or naphthyl groups, which may be mono- or polysubstituted with L1; characterised in that in a compound of general formula II wherein R 1 and R 2 are defined as hereinbefore and R 4 independently of one another denote hydrogen, C 3-18 -alkenyl, (C 1-18 -alkyl)carbonyl, (C 1-18 -alkyl)oxycarbonyl, (C 3-18 -alkenyl)carbonyl, (C 3-18 -alkenyl)oxycarbonyl, di-(C 1-18 -alkyl)aminocarbonyl, arylcarbonyl, aryl-(C 1-3 -alkyl)-carbonyl, aryl-C 1-3 -alkyl, C 1-6 -alkoxymethyl, aryl-C 1-3 -alkoxy, C 1-4 -alkylthioethyl, arylthioethyl, C 1-4 -alkylsulfonylethyl, arylsulfonylethyl, R a R b R c Si—, —CR a R b OR c , wherein two adjacent groups R 4 may be linked with each other to form a bridging group SiR a R b , CR a R b or CR a OR b —CR a OR b and wherein each alkyl group may be substituted with up to three substituents selected from fluorine, chlorine, C 1-3 -alkyl, R a R b R c Si, C 1-4 -alkoxy, with the proviso that at least one substituent R 4 is not hydrogen; R a , R b , R c independently of one another denote C 1-4 -alkyl, aryl or aryl-C 1-3 -alkyl, while the alkyl may be mono- or polysubstituted by halogen; L1 and L2 are defined as hereinbefore; and while by the aryl groups mentioned in the definition of the above groups are meant phenyl or naphthyl groups, which may be mono- or polysubstituted with L1; the protective groups R 4 not being hydrogen are cleaved.