Patent ID: 6992215

Claim:
A compound of formula II or a pharmaceutically acceptable equivalent of said compound, wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are independently hydrogen or C 1 –C 3 alkyl; and A 1 , A 2 , A 3 , A 4 and A 5 are independently hydrogen, C 1 –C 6 alkyl, C 1 –C 6 alkoxy, C 1 –C 3 perhaloalkyl, phenyl, phenoxy, benzyl, benzyloxy, hydroxy, halo, cyano, nitro, —SO 2 R 9 , —(C═O)NR 9 R 10 , —(C═O)NR 9 (CH 2 ) n COOH, —NR 9 (C═O)R 10 , —(CH 2 ) n COOH or —COOH, or any adjacent two of A 1 , A 2 , A 3 , A 4 and A 5 form with the benzene ring a fused 5- or 6-membered carbocyclic or heterocyclic aromatic ring, said heterocyclic aromatic ring containing 1 or 2 oxygen, nitrogen and/or sulfur heteroatom(s); R 9 and R 10 are independently hydrogen, C 1 –C 6 alkyl, phenyl or benzyl; and n is 1–3; provided that if A 1 , A 3 and A 5 are independently hydrogen, C 1 –C 6 alkyl, C 1 –C 6 alkoxy, halo, nitro, phenyl, phenoxy, benzyl, benzyloxy or —COOH, then neither A 2 nor A 4 are —COOH; and provided that if any adjacent two of A 3 , A 4 and A 5 form with the benzene ring a fused 5- or 6-membered carbocyclic or heterocyclic aromatic ring, said heterocyclic aromatic ring containing 1 or 2 oxygen, nitrogen and/or sulfur heteroatom(s), then A 2 is not —COOH.