Patent ID: 8377652

Claim:
A method for producing a polymalic acid (PMLA) comprising: culturing in a bioreactor plasmodia of a Physarum polycephalum strain that produces the PMLA under conditions suitable for decreasing spontaneous hydrolytic and enzymatic scission of a PMLA chain, wherein the strain is at least one strain selected from: MC3CVII, MCVIII, CH813xLU861, LU688, OX110xRA271, LU897xLU898 and LU887; isolating and purifying the PMLA from bioreactor culture broth; fractionating the PMLA according to molecular weight and collecting a plurality of molecular weight fractions of the PMLA, wherein each of the plurality of the molecular weight fractions is characterized by a molecular mass of 100,000 Da, or more.