Patent ID: 7824853

Claim:
A method for the production of a biomolecular complex, said method comprising the steps of: i) reacting a first functional element (FE 1 ) with a first binding element (BE 1 ), BE 1 comprising a nucleotide sequence that binds to a first target molecule or area (T 1 ), and forming a stock solution FE 1 -BE 1 , ii) reacting FE 1 with a second binding element (BE 2 ), BE2 comprising a nucleotide sequence that binds to a second target molecule or area (T 2 ), and forming a stock solution FE 1 -BE 2 , iii) reacting a second functional element (FE 2 ) with BE 1 , and forming a stock solution FE 2 -BE 1 , iv) reacting FE 2 with BE 2 , and forming a stock solution FE 2 -BE 2 , v) reacting a first linker molecule (L) with T 1 and T 2 and forming T 1 -L-T 2 , L being a nucleic acid and having a pre-determined physical property, and vi) reacting the stock solution of step i) and the stock solution of step iv), or the stock solution of step ii) and the stock solution of step iii), with T 1 -L-T 2 and producing said biomolecular complex wherein said biomolecular complex is and, in said biomolecular complex, each of FE 1 and FE 2 is attached to one of BE 1 and BE 2 , BE 1 is bound to T 1 and BE2 is bound to T 2 , and T 1 and T 2 are connected to each other by L.