Patent ID: 8236935

Claim:
A gem-difluorinated glycoconjugated compound of general formula I: wherein R represents a hydrogen atom or a linear or branched alkyl, benzyl, acetyl, benzoyl group, R 1 and R 2 , either identical or different, represent a hydrogen atom or a protective linear or branched alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl group or an acetal group, of the CR′R″ type, with R′and R″, either identical or different, representing a hydrogen atom or a linear or branched alkyl, aryl, benzyl, thiophene group, R 3 represents a hydrogen atom or a protective linear or branched alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl group, R 4 represents OR′″, NGR′GR″, N 3 , or a phthalimide with R′″ representing a hydrogen atom or a linear or branched alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl protective group, and with GR′ and GR″, either identical or different representing a hydrogen atom or a linear or branched alkyl, benzyl, benzoyl, acetyl, alkyloxycarbonyl, allyloxycarbonyl, benzyloxycarbonyl group, R 5 represents a free or protective hydroxyl group or a halogen, R 6 represents a hydrogen atom or a linear or branched alkyl, acetyl, benzyl, PO 3 H, PO 3 Na group, as well as its derivatives in the state of a mineral or organic acid addition salt.