Patent ID: 8431700

Claim:
A compound having a structure represented by a formula: wherein each ---- is a covalent bond; wherein each R is independently hydrogen or optionally substituted C1-6 aliphatic, or two R groups on the same nitrogen are taken together with the nitrogen to form a 4-8 membered heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur; wherein R 1 is optionally substituted organic residue comprising 1 to 12 carbon atoms; wherein R 2 is hydrogen; wherein R 3 is hydrogen; wherein R 4 is hydrogen; wherein R 5 is hydrogen; wherein each Y is C—R 6 ; wherein each R 6 is independently selected from hydrogen, halogen, OR, nitrile, nitro, SR, N(R) 2 , and optionally substituted organic residue comprising from 1 to 6 carbon atoms; wherein Ar comprises an optionally substituted aromatic cyclic moiety having from 4 to 16 carbons; or a pharmaceutically acceptable salt thereof.