Patent ID: 7589068

Claim:
A compound of the Formula E: wherein: a is 0 or 1; b is 0 or 1; n is 0, 1 or 2: p is 0, 1 or 2; Ring K is selected from: Q is selected from: 2-azepinone, benzimidazolyl, benzimidazolonyl, 2-diazapinone, imidazolyl, 2-imidazolidinone, indolyl, isoquinolinyl, morpholinyl, piperidyl, piperazinyl, pyridyl, pyrrolidinyl, 2-piperidinone, 2-pyrimidinone, 2-pyrollidinone, quinolinyl, tetrazolyl, tetrahydrofuryl, tetrahydroisoquinolinyl, and thienyl, optionally substituted with one to three substituents selected from R 6b ; R 1 is selected from: oxo, (C═O) a O b (C 1 -C 10 )alkyl, CO 2 H, halo, OH, CN, (C 1 -C 6 )alkoxy, O(C═O)(C 1 -C 6 )alkyl and N(R b ) 2 ; R 2 is selected from: oxo, (C═O) a O b (C 1 -C 10 )alkyl, CO 2 H, halo, OH, CN, (C 1 -C 6 )alkoxy, O(C═O)(C 1 -C 6 )alkyl,(C 2 -C 10 )alkenyl and N(R b ) 2 , said alkenyl optionally substituted with oxo; R 6b is selected from: optionally substituted with 1 to 3 substituents selected from oxo, OH, N(R b ) 2 , halogen and O a (C 1 -C 6 )alkyl; and R b is independently selected from H and (C 1 -C 6 )alkyl; or a pharmaceutically acceptable salt or a stereoisomer thereof.