Patent ID: 8718765

Claim:
A device for analysis of an endocardial acceleration (EA) signal, wherein the device has one or more parameters, the device comprising: means for continuously collecting the EA signal over a sequence of cardiac cycles; means for dividing the collected EA signal into a plurality of EA sub-signals, wherein each of the plurality of EA sub-signals corresponds to a single cardiac cycle of the sequence of cardiac cycles; means for isolating in each of the plurality of EA sub-signals at least one EAx component, wherein the at least one EAx component is associated with one of an S 1 heart sound, an S 2 heart sound, an S 3 heart sound, or an S 4 heart sound, and wherein the means for isolating the at least one EAx component is configured to isolate the EAx component over an analysis window having a predefined duration, wherein the analysis window comprises a timeframe during which isolation of the at least one EAx component is performed; means for cross-correlating the EAx components of the plurality of EA sub-signals, wherein the means for cross-correlating comprises: means for defining a reference cycle comprising a reference EA sub-signal; means for determining, for each of the plurality of EA sub-signals, a correlation coefficient based on the cross-correlation between the respective EA sub-signal and the reference EA sub-signal; means for determining, for each of the plurality of EA sub-signals, a calibration delay to calibrate the respective EA sub-signal against the reference EA sub-signal; means for determining a plurality of validation criteria; means for selecting a subset of EA sub-signals from among the plurality of EA sub-signals based on the plurality of validation criteria; means for averaging the selected subset of EA sub-signals and generating an output average overall EA sub-signal; means for detecting one of a change in a condition of a patient or an occurrence of a predetermined event in the patient; and means for dynamically adapting, on detection of said change of the condition or said predetermined event, at least one of said validation criteria or at least one of the one or more parameters of the device.