Patent ID: 8575158

Claim:
A compound of formula (I): wherein X represents —NH—, —O— or a bond; Y represents (C 1 -C 4 )alkandiyl; Z represents O or S; n represents 0 or 1; R 1 represents (C 4 -C 6 )alkyl; (C 1 -C 4 )alkyl which is mono-substituted with (C 3 -C 6 )cycloalkyl, (C 1 -C 4 )alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted aryl-(C 1 -C 2 )alkoxy, optionally substituted heteroaryl-(C 1 -C 2 )alkoxy, optionally substituted heteroarylsulfanyl or —NR 8 R 9 ; (C 2 -C 4 )alkenyl which is mono-substituted with optionally substituted aryl; (C 2 -C 4 )alkynyl which is mono-substituted with optionally substituted aryl; (C 3 -C 6 )cycloalkyl which is mono- or di-substituted with (C 1 -C 4 )alkyl, mono-substituted with (C 1 -C 4 )alkoxy, mono-substituted with optionally substituted aryl or mono-substituted with optionally substituted heteroaryl; optionally substituted aryl; or a 10-membered partially unsaturated ring system; R 2 represents hydrogen, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, (C 1 -C 4 )fluoroalkyl, halogen, (C 1 -C 4 )alkylsulfonyl, phenylsulfonyl or (C 1 -C 4 )alkylsulfonylamino; R 3 represents hydrogen, (C 1 -C 4 )alkoxy or halogen; R 4 represents hydrogen, (C 1 -C 4 )alkoxy, halogen, (C 1 -C 4 )alkylsulfonyl, optionally substituted aryl or optionally substituted heteroaryl; R 5 represents hydrogen, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, (C 1 -C 4 )fluoroalkyl, halogen, cyano, —CONH 2 , optionally substituted aryl, optionally substituted heteroaryl, (C 1 -C 4 )alkylsulfonyl, phenylsulfonyl or dimethylamino-sulfonyl; and R 6 represents hydrogen or halogen; or R 5 and R 6 together form a methylendioxy-group; R 7 represents hydrogen or methyl; R 8 represents hydrogen or methyl; R 9 represents optionally substituted aryl, optionally substituted arylsulfonyl or optionally substituted heteroarylsulfonyl; and R 10 represents —C(O)OH, —C(O)NH—CN, —C(O)NH—OH, —C(O)NH—S(O) 2 CF 3 or optionally substituted heteroaryl; with the proviso that R 1 is different from optionally substituted aryl if X represents —NH— or a bond; or a salt thereof.