Patent ID: 8394587

Claim:
A method for predicting prenatal loss of a male conceptus or embryo, comprising the steps of: (a) providing a biological sample from a pregnant woman; (b) isolating a nucleic acid from said biological sample; (c) performing a polymerase chain reaction (PCR) on said isolated nucleic acid to produce an amplicon; (d) assessing said amplicon for the presence of adenine (A) at SNP GTF2H4 rs3909130; and (e) predicting an increased risk of prenatal loss of said male conceptus or embryo in said pregnant woman by said presence of adenine (A) at said SNP GTF2H4 rs3909130, wherein the presence of said adenine (A) at said SNP GTF2H4 rs3909130 is indicative of an increased risk of prenatal loss of said male conceptus or embryo.