Patent ID: 6897223

Claim:
A compound of formula wherein A is —NR(C═O); wherein each R, R 1 , R 2 , and R 3 are the same or different, where ever they appear, and each is independently selected from the group consisting of (C 1 -C 6 )alkyl-, (C 2 -C 6 )alkenyl-, (C 2 -C 6 )alkynyl-, (C 3 -C 10 )cycloalkyl-, (C 6 -C 10 )aryl-, (C 1 -C 10 )heterocyclyl-, (C 1 -C 10 )heteroaryl-, (C 3 -C 10 )cycloalkyl-(C 1 -C 6 )alkyl-, (C 6 -C 10 )aryl-(C 1 -C 6 )alkyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heterocyclyl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heteroaryl-(C 1 -C 6 )alkyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkenyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkynyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkynyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkynyl-, (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkynyl-; wherein each of the aforesaid group members, (C 1 -C 6 )alkyl-, (C 2 -C 6 )alkenyl-, (C 2 -C 6 )alkynyl-, (C 3 -C 10 )cycloalkyl-, (C 6 -C 10 )aryl-, (C 1 -C 10 )heterocyclyl-, (C 1 -C 10 )heteroaryl-, (C 3 -C 10 )cycloalkyl-(C 1 -C 6 )alkyl-, (C 6 -C 10 )aryl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heterocyclyl-(C 1 -C 6 )alkyl-, (C 1 -C 10 )heteroaryl-(C 1 -C 6 )alkyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkenyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkenyl-, (C 1 -C 10 )heteroaryl-(C 2 -C 6 )alkenyl-, (C 3 -C 10 )cycloalkyl-(C 2 -C 6 )alkynyl-, (C 6 -C 10 )aryl-(C 2 -C 6 )alkynyl-, (C 1 -C 10 )heterocyclyl-(C 2 -C 6 )alkynyl-, and (C 1 -C 10 )hereroaryl-(C 2 -C 6 )alkynyl-, may be optionally independently substituted with one to three substituents selected from the group consisting of hydrogen, halogen, hydroxy, —CN, (C 1 -C 4 )alkyl-, (C 1 -C 4 )alkoxy-, CF 3 —, CF 3 O—, (C 6 -C 10 )aryl-, (C 1 -C 10 )heteroaryl-, (C 6 -C 10 )aryl-(C 1 -C 4 )alkyl-, (C 1 -C 10 )heteroaryl-(C 1 -C 4 )alkyl-, HO(C═O)—, (C 1 -C 4 )alkyl-(O)(C═O)—, (C 1 -C 4 )alkyl-(O)(C═O)(C 1 -C 4 )alkyl-, (C 1 -C 4 )alkyl-(C═O)—, (C 1 -C 4 )alkyl-(C═O)(C 1 -C 4 )alkyl-, —(S═O)R, —(SO 2 )R, and NR 7 R 8 wherein R 7 and R 8 are independently selected from hydrogen, (C 1 -C 6 )alkyl; wherein each R and R 3 may forther independently be hydrogen; R 4 is selectcd from the group consisting of hydrogen and (C 1 -C 6 )alkyl-, and R 4 may be optionally substituted with one to three substituents selected from the group consisting of halogen, hydroxy, —CN, CF 3 -, and CF 3 O—; or a pharmaceutically acceptable salt thereof.