Patent ID: 7932286

Claim:
A method of reducing pain associated with colonic viscerosensitivity and spasticity induced during a colonic examination chosen from colonic endoscopy and of barium/air contrast colonic radiography and virtual colonoscopy of a non-sedated patient, said method comprising prescribing and/or administering to said patient a pharmaceutically effective oral, sub-lingual, nasal or transdermal dose of a non-centrally-acting opioid agonist chosen from trimebutine maleate and N-desmethyl trimebutine, their isomers, or enantiomers, and mixtures thereof at least once a day for a period of at least two to seven days before said colonic examination, wherein a dosage of said non-centrally-acting opioid agonist is about 300 mg to 1.2 g per day.