Patent ID: 7491735

Claim:
A compound or a pharmaceutically acceptable salt thereof, having the formula: where n is 0 or 1; R 1 is pyridinyl or pyrimidinyl, each optionally substituted by one or more halogen, alkyl, amine or heteroaryl; R 2 is phenyl, pyridinyl, thiazolyl, furanyl, or thiophenyl, each of which is optionally linked to one or more C1-C6 alkyl, alkoxy, trifluoromethyl, carboxylalkyl, cyano, or halogen; R 3 is phenyl, pyridinyl, thiazolyl, oxazolyl, pyrimidinyl, indolyl, indolinyl, isoindolinyl, 1,3-benzodioxolyl, 1,4-benzodioxanyl, benzofuranyl, 2,3-dihydroxybenzofuranyl or phthalanyl, each of which is optionally linked to one or more C1-C6 alkyl, trifluoromethyl, oxotrifluoromethyl, carboxylalkyl, cyano, halogen, sulfanyl, SO 2 R 9 , where R 9 is alkyl, amine or amino alkyl, C(O)R 10 , where R 10 is alkyl, amine, morpholine, NMe 2 , N(OMe)Me, NHPh, piperidine, NHMe, piperazine, NHCH 2 C(O)OMe or PhC(O)OH, OR 11 , where R 11 is H, alkyl, (CH 2 ) 2 OMe, CH 2 C(O)NH 2 , CH 2 C(O)NHNH 2 , CH 2 C(O)OCMe 3 , CH 2 C(O)OMe, CH 2 C(O)OH, PhC(O)OH, PhC(O)NH 2 , SO 2 Me, C(O)Me, C(O)OMe, C(O)NEt 2 , C(O)NMe 2 or NHR 12 , where R 12 is H, C(O)Me, C(O)CF 3 , SO 2 Me, C(O)NH 2 , C(O)NMe 2 or NO 2 , CH 2 PhC(O)OH, SOMe, CH 2 NHC(O)Me, morpholine, CH═CHC(O)OMe, CH═CHC(O)OH, and R 4 is hydrogen or alkyl.