Patent ID: 8755577

Claim:
A method for objective, non-invasive and in vivo assessment and rating of psoriasis lesion scaliness using digital imaging comprising: i. acquiring a 3D digital image of a patient; ii. averaging a subtraction result to determine a Psoriasis Area and Severity Index (PASI) scaliness value, wherein the subtraction result is determined by subtracting an estimated surface from an actual lesion surface; wherein said method for objective, non-invasive and in vivo assessment and rating of psoriasis lesion scaliness using digital imaging comprises sub-steps of: a. acquiring 3D and 2D images of assessed surfaces; b. segmenting a psoriasis lesion area from a normal skin area; c. mapping pixel coordinates of a segmented psoriasis lesion area in 2D image to a segmented psoriasis lesion area in 3D image; d. partitioning said segmented psoriasis lesion area into at least one sub-divided lesion area; e. constructing the estimated surface of the sub-divided lesion area using a polynomial surface fitting; f. determining a goodness of the polynomial surface fitting of the sub-divided lesion area; g. subtracting the respective estimated surface from the actual lesion surface; h. averaging an absolute value of the subtraction result to determine a surface roughness of each of the at least one sub-divided lesion area; i. averaging the surface roughness of each of the at least one sub-divided lesion area to obtain an overall surface roughness; j. correlating the overall surface roughness with a PASI scaliness score.