Patent ID: 8052984

Claim:
A composition for topical treatment of fungal infections of nails, the composition comprising a plurality of beads, wherein the beads contain a mixture comprising: (a) about 1% to 6% weight/weight of positively charged terbinafineHCl, (b) 1%-20% weight/weight phospholipid, wherein the phospholipid comprises lecithin, (c) at least one solubilizer selected from the group consisting of water, ethanol, polyols, glycols, surfactants, phospholipids, polysorbate 20, polysorbate 80, and complexing agents, (d) at least one enhancer selected from the group consisting of ethanol, alkanols, fatty alcohols, fatty acids, fatty acid esters, polyols, polysorbate 20, polysorbate 80, propylene glycol, 1,3-butanediol, terpenes, amides, cyclic amides, pyrrolidone derivatives, essential oils, phospholipids and surfactants, (e) at least one antioxidant, (f) at least one preservative, (g) at least one humectant, and (h) at least one viscosity increasing agent, and wherein the mixture does not comprise urea, wherein the plurality of beads are suspended in a delivery vehicle.