Patent ID: 8715734

Claim:
A process for preparing a stable granulate for reconstitution with water into an oral aqueous suspension comprising micronized amoxicillin trihydrate and sugar, the process comprising: screening a mixture of amoxicillin trihydrate and sugar through a first sieve to provide a sieved mixture; extruding the sieved mixture with a granulation liquid comprising water to obtain a wet extruded mass; screening the wet extruded mass through a second sieve to provide a sieved wet extruded mass; drying the sieved wet extruded mass to form a dried sieved extruded mass; and homogenizing the dried sieved extruded mass to obtain a granulate comprising micronized particles of amoxicillin, wherein the granulate is dissolvable in water to form a smooth suspension and wherein the granulate is free of pharmaceutically acceptable excipients other than sugar.