Patent ID: 7196189

Claim:
An isolated nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide comprising the amino acid sequence of SEQ ID NO:91 having at least one amino acid change selected from the group consisting of: (a) a phenylalanine changed to valine, isoleucine, leucine, or methionine at position 31; (b) a glutamine changed to lysine, arginine, or histidine at position 41; (c) a threonine changed to valine, isoleucine, leucine, or methionine at position 52; (d) a threonine changed to aspartic acid, glutamic acid, asparagine, or glutamine at position 52; (e) a cysteine changed to lysine, arginine, or histidine at position 73; (f) a proline changed to serine, threonine, or cysteine at position 101; (g) a proline changed to aspartic acid, glutamic acid, asparagine, or glutamine at position 101; (h) a valine changed to isoleucine, leucine, or methionine at position 111; (i) a serine changed to valine, isoleucine, leucine, or methionine at position 133; (j) a glutamic acid changed to valine, isoleucine, leucine, or methionine at position 141; (k) a glutamic acid to lysine, arginine, or histidine at position 141; (l) a cysteine changed to phenylalanine, tyrosine, or tryptophan at position 153; (m) a cysteine changed to lysine, arginine, or histidine at position 153; (n) a threonine changed to glycine, alanine, or proline at position 281; (o) an asparagine changed to valine, isoleucine, leucine, or methionine at position 367; (p) an asparagine changed to phenylalanine, tyrosine, or tryptophan at position 367; (q) a proline changed to serine, threonine, or cysteine at position 389; and (r) a proline changed to valine, isoleucine, leucine, or methionine at position 389; wherein the polypeptide further comprises the amino acid sequence of SEQ ID NO:95 immediately amino terminal to the amino acid sequence of SEQ ID NO:91.