Patent ID: 7070626

Claim:
A (p-aminohydroxyphenyl)acrylamide derivative of formula (I), or a physiologically tolerated, water-soluble salt thereof: wherein R1 denotes hydrogen, a halogen atom, a C 1 -C 4 -alkyl group, a C 1 -C 4 -hydroxyalkyl group or a C 1 -C 4 -alkoxy group; R2 and R3 independently of each other denote hydrogen or a C 1 -C 6 -alkyl group; R4 denotes a C 1 -C 2 -alkyl group, a methoxy group or a C 2 -C 4 -hydroxyalkyl group; R5 denotes a C 2 -C 4 -hydroxyalkyl group; R6 denotes hydrogen, a carboxy group or an aminocarbonyl group; R7 and R8, independently of each other, denote hydrogen, a hydroxyl group, an aminocarbonyl group, a methylthiomethyl group, a phenyl-substituted or hydroxyl-substituted phenyl group or a group of formula R9, R10, R11, R12 and R13, independently of each other, denote hydrogen, a halogen atom, a cyano group, a hydroxyl group, a C 1 -C 4 -alkoxy group, a C 1 -C 4 -hydroxyalkoxy group, a C 1 -C 6 -alkyl group, a C 1 -C 4 -alkyl thioether group, a mercapto group, a nitro group, an amino group, an alkylamino group, a C 1 -C 4 -hydroxyalkylamino group, a dialkylamino group, a di(C 1 -C 4 -hydroxyalkyl)amino group, a (C 3 -C 4 -dihydroxyalkyl)-amino group, a (C 1 -C 4 -hydroxyalkyl)-C 1 -C 4 -alkylamino group, a trifluoromethyl group, a —C(O)H group, a —C(O)CH 3 — group, a —C(O)CF 3 group, an —Si(CH 3 ) 3 group, a C 1 -C 4 -hydroxyalkyl group or a C 3 -C 4 -dihydroxyalkyl group, or two adjacent R9 to R13 groups form an —O—CH 2 —O— bridge; R14 denotes a C 1 -C 4 -alkyl group, a benzyl group or a C 2 -C 4 -hydroxyalkyl group; R15 denotes hydrogen or a C 1 -C 6 -alkyl group; R16 denotes hydrogen, a hydroxyl group, a carboxy group, an aminocarbonyl group or a hydroxymethyl group; and R17 denotes hydrogen or a C 1 -C 6 -alkyl group.