Patent ID: 7371737

Claim:
A compound of formula (1): or a pharmaceutically acceptable salt, a tautomer, a stereoisomer, or a mixture of any of the foregoing wherein: R 1 is chosen from —[X—(CH 2 ) n ] m —Y, wherein X is chosen from NH and oxygen, n is chosen from 0, 1, 2 and 3, m is chosen from 0 and 1, and Y is chosen from an optionally substituted 5- or 6-membered aromatic or non-aromatic ring comprising 0, 1 or 2 hetero-atoms chosen from N, O and S; and a nitro group; R 2 is chosen from hydrogen, C 1-3 -alkyl, ribose, —CH 2 —O—CO—O-t-butyl, and aryl-(C 1-3 )alkyl; and R 3 is chosen from hydrogen; halogen; NH 2 ; —NH—(C 1-6 )alkyl; —N-di(C 1-6 )alkyl; —NH-cyclo(C 3-8 )alkyl; C 2-4 -alkenyl(hetero)aryl and C 2-4 -alkynyl(hetero)aryl, wherein the hetero-atoms are chosen from N, O, and S and optionally, wherein the (hetero)aryl groups are substituted; and an optionally substituted 5- or 6-membered aromatic and non-aromatic ring, comprising 0, 1 or 2 hetero-atoms chosen from nitrogen, oxygen and sulfur.