Patent ID: 8124629

Claim:
A compound of formula I: or a pharmaceutically acceptable salt or ester thereof, wherein: Q is C(H) or N; X is selected from the group consisting of: (1) C(O), (2) C(H)(H), (3) C(H)(OH), (4) C(F)(F), (5) C(H)(O—CH 3 ), and (6) C(H)(CH 3 ); R 1 and R 2 , independently of each other, are selected from the group consisting of: (1) hydrogen, (2) halogen, (3) lower alkyl, optionally substituted by halogen, and (4) lower alkoxy, or alternatively, R 1 and R 2 are bonded together to form methylenedioxy; R 3 is selected from the group consisting of: (1) hydrogen, (2) halogen, (3) lower alkyl, optionally substituted by halogen, (4) lower alkoxy, and (5) cyano; R 4 is S(O) 2 —R 7 wherein R 7 is selected from the group consisting of: (a) lower alkyl optionally substituted by halogen or phenyl, (b) amino, (c) lower alkylamino, (d) lower dialkylamino, (e) acetylamino, (f) N-acetyl-N-lower alkylamino, (g) lower heterocycloalkyl optionally substituted by a substituent selected from the group consisting of: (i) lower alkyl, (ii) phenyl optionally substituted by halogen, and (iii) lower alkoxycarbonyl; and (h) phenyl or benzyl, wherein said phenyl or benzyl is optionally substituted by halogen or trifluoromethyl; and R 5 and R 6 , independently of each other, are hydrogen or methyl.