Patent ID: 8702960

Claim:
A method for operating a measurement for a sample on an electrochemical test strip, wherein the sample includes an interference material and an analyte concentration, the method comprising steps of: providing the electrochemical test strip, wherein the electrochemical test strip includes two electrodes, a hydrogen peroxide and a reagent containing a mediator having a reduction state and an oxidation state; applying a detection voltage between the two electrodes during a sample presence detection period; applying an incubation voltage between the two electrodes during an incubation period succeeding a moment when the electrochemical test strip is detected to have the sample thereon, wherein: the incubation voltage has a maximum voltage value, the maximum voltage value is high enough to oxidize the mediator from the reduction state to the oxidation state and is low enough to avoid oxidizing the hydrogen peroxide, the incubation voltage includes an incubation set of plural pulse voltages, each of which is in a range of 0.1-0.6 volt, each pulse of the incubation set of plural pulse voltages has an incubation pulse width in a range of 100-500 μs, and the incubation set of plural pulse voltages has an incubation pulse interval between two adjacent pulses therein, wherein the incubation pulse interval is in a range of 100-500 ms; oxidizing the interference material by applying a first voltage between the two electrodes during an interference-removal period after the incubation period, wherein the first voltage includes one of a first fixed voltage and a first set of plural pulse voltages and is in a range of 0.15-1 volt, and the first voltage is applied for 0.1-1 s; measuring the analyte concentration by applying a second voltage between the two electrodes during a test period, wherein the first voltage is higher than the second voltage, the second voltage includes a second fixed voltage and is in a range of 0.1-0.9 volt, and the second voltage is applied for 0.2-10 s; and during a transition interval between the interference-removal period and the test period, performing one of following operations: causing a power-off to result in an open-circuit state in a measuring circuit; and applying a zero voltage between the two electrodes, wherein the transition interval lasts 0.01-0.5 s.