Patent ID: 8460665

Claim:
A method of stimulating remyelination of central nervous system axons in a human with an antibody comprising the heavy chain variable regions CDR1, CDR2 and CDR3 sequences as set out in FIG. 5 and SEQ ID NO:7 and the light chain variable region CDR1, CDR2 and CDR3 sequences as set out in FIG. 6 and SEQ ID NO:9; the antibody selected from the group consisting of: a human monoclonal antibody mAb sHIgM22 (LYM 22), active fragments thereof, or recombinant antibodies derived therefrom; the method comprising: administering said antibody to a patient in an amount of 1.25 μg antibody/kg body weight to 2.5 μg antibody/kg body weight.