Patent ID: 8399453

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof: wherein m is 1 or 2; R1 is H, halogen, alkyl, haloalkyl, alkoxy, amine or aryl optionally substituted with one or more substituents; R2 is H, alkyl, arylalkyl or alkoxycarbonyl; R3 is H or alkyl; R4 is H, alkyl or hydroxyalkyl or R3 and R4 form part of a heterocyclo ring; R5 is H or alkyl; n is 1, 2 or 3; and A and B are fused to and form part of an unsubstituted or substituted indole; provided that if A and B are fused to positions 2 and 3 of an unsubstituted indole, n is 1 or 2, R2 and R3 are H, m is 1 and R1 is in position 6 of the spiro oxindole, then R1, R4 and R5 are not all H; or if R1 is H, then R4 is not methyl when R5 is H and R5 is not methyl when R4 is H; or if R1 is Br, then R4 and R5 are not both H, and R4 is not methyl when R5 is H, and R5 is not methyl when R4 is H.