Patent ID: 7175885

Claim:
A method of manufacturing a combinatorial sensor array for detecting an analyte in a fluid, comprising the steps of: providing a first solution of a first organic material at a concentration x in a first solvent, a second solution of a second organic material at a concentration y in a second solvent, and a substrate having a first preselected region and a second preselected region; contacting said first region with said first solution at said concentration x; contacting the second region with the first solution at said concentration x+a; contacting the first region with said second solution at said concentration y; and contacting the second region with the second solution at said concentration y+b, wherein, the first region forms a first sensor having a blend of the first organic material at mole fraction m and the second organic material at mole fraction 1−m and the second region forms a second sensor having a blend of the first organic material at mole fraction n and the second organic material of mole fraction 1−n, said two sensors forming a combinatorial sensor array, wherein the sensor array is configured to be optically connected with a detector, wherein the first region and the second region on the substrate are physically separated, and wherein the first region is recessed below the surface of the substrate in a first well and the second region is recessed below the surface of the substrate in a second well, the first well physically separated from the second well.