Patent ID: 8906934

Claim:
A method for treating cell proliferative disorders caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I): wherein G is CH or nitrogen atom; W is an oxygen atom, NR 1 or S(O)n; n is 0, 1 or 2; R 1 and R 3 independently represent hydrogen atom or an optionally substituted group selected from alkyl, cycloalkyl, alkenyl, alkynyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heterocyclyloxy-alkyl and alkoxycarbonyl group; R 2 is hydrogen or halogen atom, or an optionally substituted group selected from aryl, cycloalkyl and heterocyclyl group; R 4 is hydrogen or halogen atom, or an optionally substituted alkyl or alkenyl group; R 5 is hydrogen or halogen atom; R 6 is hydrogen atom or NHR 7 ; R 7 is hydrogen atom, an optionally substituted group selected from alkyl, aryl, cycloalkyl and heterocyclyl group or —COR 1 wherein R 1 is as defined above; or a pharmaceutically acceptable salt thereof, with the proviso that the following compounds are excluded: 2,5-di(pyridin-4-yl)-thiophene-3-carboxylic acid amide, 2,5-di(pyridin-4-yl)-thiophene-3-carboxylic acid methylamide, 2,5-di(pyridin-4-yl)-4-methyl-pyrrole-3-carboxylic acid amide, 5-pyridin-4-yl-furan-3-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide, 5-pyridin-4-yl-furan-3-carboxylic acid (1-methyl-1,2,3,4-tetrahydro-quinolin-7-yl)-amide and N-[2-amino-1-(2,4-dichlorobenzyl)ethyl]-5-[2-(methylamino)pyrimidin-4-yl]thiophene-3-carboxamide, wherein the cell proliferative disorder is selected from the group consisting of cervical cancer, colon cancer, ovarian cancer, pancreatic cancer, breast cancer, ductal breast cancer, epidermal cancer, lung cancer, large cell lung cancer, squamous cell lung cancer, small cell lung cancer, non-small cell lung cancer, thyroid cancer, medullary thyroid cancer, papillary thyroid cancer, astrocitoma, neuroblastoma, glioblastoma, gliosarcoma, melanoma and osteosarcoma.