Patent ID: 8624025

Claim:
A method of prophylaxis of a human rhinovirus (HRV) infection in a respiratory tract of a mammal, comprising administering to the mammal an effective amount of a composition comprising a compound of formula II: wherein: R 1 is hydrogen, C 1-4 -alkyl, halo, hydroxyl, mercapto, trifluoromethyl, amino, mono or di(C 1-4 alkyl)amino, cyano, formyl, —CH═NO—C 1-4 -alkyl, C 1-4 alkoxy, C 1-4 haloalkoxy, aryloxy, C 1-4 -alkylthio, or aryl; Y is O, S, NH or NMe; Z is CH or N; Alk is C 1-6 alkylene; and R 11 is OR 10 or SR 10 , where R 10 is C 1-4 -alkyl; or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier.