Patent ID: 7709218

Claim:
A method for detecting over-expression of a polypeptide in a sample derived from a human comprising: (a) detecting the level of a polypeptide in a sample derived from a human, wherein the sample derived from the human is selected from the group consisting of blood, serum, plasma, a tissue biopsy, cancerous tissue, urine, saliva, synovial fluid, and spinal fluid; and (b) comparing the detected level in step (a) to a normal control-sample, wherein an increased detected level in step (a) as compared to the normal control is indicative of over-expression of the polypeptide in the sample derived from the human, wherein the polypeptide is selected from the group consisting of: (i) a polypeptide having the amino acid sequence of SEQ ID NO:2; (ii) a polypeptide encoded by the cDNA clone of ATCC Deposit No. 97810; (iii) a polypeptide comprising amino acid residues 31-300 of SEQ ID NO:2; (iv) a polypeptide comprising amino acid residues 31-283 of SEQ ID NO :2; (v) a polypeptide comprising the mature form of a polypeptide encoded by the cDNA clone of ATCC Deposit No. 97810, wherein the mature form lacks the leader sequence; and (vi) a polypeptide comprising the soluble extracellular domain of a polypeptide encoded by the cDNA clone of ATCC Deposit No. 97810.