Patent ID: 8236792

Claim:
A compound of Formula (I): wherein R 1 and R 2 taken together with the nitrogen to which they are attached form where m is 1 or 2; n is 1 or 2; R a is H, C 1-6 alkyl, cycloalkyl, heterocycloalkyl, or benzyl; and R b and R c are each independently H or C 1-4 alkyl; or R b and R c taken together with the nitrogen to which they are attached form a heterocycloalkyl ring; R 3 is H; C 1-6 alkyl; C 2-6 alkyl substituted with OH, —OC 1-4 alkyl, fluoro, or cycloalkyl; cycloalkyl; heterocycloalkyl; —COC 1-6 alkyl; —CO-(cycloalkyl); benzoyl; —CO 2 -benzyl; —SO 2 C 1-4 alkyl; —SO 2 -(cycloalkyl); or —SO 2 -phenyl; R 4 , R 5 , and R 6 are defined as one of a), b) or c); a) R 4 is —X—R d and R 5 and R 6 are each H; b) R 5 is —X—R d and R 4 and R 6 are each H; c) R 6 is —CH 2 —R e and R 4 and R 5 are each H; X is O; R d is H or C 1-6 alkyl, or a phenyl, benzyl, cycloalkyl, heterocycloalkyl, or monocyclic heteroaryl group, each group unsubstituted or substituted with one or two R f substituents; where each R f substituent is independently selected from the group consisting of: halo; —C 1-4 alkyl; —C 2-4 alkyl substituted with OH, F, or —OC 1-4 alkyl; —CHF 2 ; —CF 3 ; —OH; —OC 1-4 alkyl; —SC 1-4 alkyl; —SO 2 C 1-4 alkyl; —CN; —CONR g R h ; and —NO 2 ; or two R f substituents together form —O(CH 2 ) 1-2 —O—; where R g and R h are each independently —H or —C 1-4 alkyl; and R e is phenyl or monocyclic heteroaryl, each unsubstituted or substituted with one or two R f substituents; or a pharmaceutically acceptable salt thereof.