Patent ID: 7745152

Claim:
A method for determining the genotoxicity of a test compound, said method comprising: (a) contacting a viable murine myoblast test cell with said test compound; (b) determining the change in expression level of a murine indicator gene selected from the group consisting of 4833427G06 Rik (RIKEN cDNA) (SEQ ID NO:5) and murine Dda3 (Differential display and activated by p53) wherein an increase in expression of at least 1.5-fold in said murine myoblast test cell, compared to a murine myoblast cell comprising 4833427G06 Rik (RIKEN cDNA) (SEQ ID NO: 5) or murine Dda3, that is not exposed to the test compound, indicates that said test compound exhibits genotoxicity.