Patent ID: 7985427

Claim:
A gastric juice-resistant device for releasing active substance carriers which have a delayed intestinal passage from a gastric juice-resistant enclosure which disintegrates in the presence of intestinal juice, wherein the active substance carriers containing at least one active substance are present in the form of a multiparticulate preparation which is enclosed in said gastric juice-resistant enclosure, the individual particles of said multiparticulate preparation comprise a film of at least two layers, of which at least one has mucoadhesive properties and contains said active substance, the said device contains a blowing agent preparation comprising a blowing agent which generates gas on contact with liquid, said blowing agent causing the dispersion of the individual particles of the multiparticulate active substance-containing preparation, said blowing agent preparation is present as a powder mixture or as pressed pieces or as pellets or tablets, the said multiparticulate preparation and said blowing agent preparation are stacked on top of each other in an alternating fashion in said device, and said device having an elongated shape and two ends at opposite sides of the device, and said disintegration starts at said ends of the device.