Patent ID: 8784782

Claim:
A method for modulating the savory taste of a comestible composition comprising combining the comestible composition with a savory flavor modulating amount of at least one compound having the formula: or a comestibly acceptable salt thereof, so as to form a modified comestible composition; wherein i) Ar is a monocyclic or bicyclic aryl or heteroaryl radical comprising one or two aromatic rings independently selected from benzene rings and five or six membered heteroaryl rings, each aromatic ring optionally having one, two, or three R 20 substituent radicals bound thereto, wherein each R 20 radical is independently selected from hydroxyl, NH 2 , SH, halogen, or a C 1 -C 4 organic radical; ii) hAr 1 is a five or six-membered heteroaryl ring radical comprising at least two ring carbon atoms and one to three ring heteroatoms independently selected from O, N, or S, wherein any remaining members of the heteroaromatic ring are independently selected from CR 6 , N, NR 7 ; iii) X is O, S, S(O), SO 2 , CR 8 R 9 , or NR 10 ; iv) n is the integers zero, one, two, or three; v) R 3 , R 4 , R 8 and R 9 are independently selected from hydrogen, oxygen, hydroxyl, NH 2 , SH, halogen, or a C 1 -C 4 organic radical, and R 7 and R 10 are independently selected from hydrogen, hydroxyl, or a C 1 -C 4 organic radical, and R 6 is hydrogen, halogen, or a C 1 -C 4 organic radical; and vi) hAr 2 is a five or six-membered heteroaryl ring having at least one ring carbon atom and at least one ring nitrogen atom, and wherein the remaining members of the heteroaryl ring are independently selected from CR 30 , CH, N, NR 31 , O, and S, wherein the number of CR 30 is zero, one or two, and each R 30 is independently selected from hydroxyl, NH 2 , NO 2 , SH, SO 3 H, P(O)(OH) 2 , a halogen, or a C 1 -C 4 organic radical, and each R 31 is independently selected from hydrogen, or a C 1 -C 4 organic radical.