Patent ID: 8455646

Claim:
A compound of formula (I): wherein: R1 is H or a group selected from the group consisting of (C 1 -C 10 )-alkyl, aryl, (C 3 -C 8 )-cycloalkyl, arylalkyl, and heteroaryl, each of which may be optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (═O), SH, NO 2 , CN, CON(R5) 2 , COOH, NHCOR5, COR5, CO 2 R5, CF 3 , (C 1 -C 10 )-alkoxycarbonyl, (C 1 -C 10 )-alkylsulfanyl, (C 1 -C 10 )-alkylsulfinyl, (C 1 -C 10 )-alkylsulfonyl, (C 1 -C 10 )-alkyl, and (C 1 -C 10 )-alkoxyl; R2 is a group selected from the group consisting of (C 1 -C 10 )-alkyl, aryl, (C 3 -C 8 )-cycloalkyl, arylalkyl, and heteroaryl, each of which may be optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (═O), SH, NO 2 , CN, CON(R5) 2 , COOH, NHCOR5, COR5, CO 2 R5, CF 3 , (C 1 -C 10 )-alkoxycarbonyl, (C 1 -C 10 )-alkylsulfanyl, (C 1 -C 10 )-alkylsulfinyl, (C 1 -C 10 )-alkylsulfonyl, (C 1 -C 10 -alkyl, and (C 1 -C 10 )-alkoxyl; R3 is aryl, (C 3 -C 8 )-cycloalkyl, heteroaryl, arylalkyl, or heteroarylalkyl, each of which may be optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (═O), SH, NO 2 , CN, CON(R5) 2 , COOH, CO 2 R5, CF 3 , (C 1 -C 10 )-alkoxycarbonyl, (C 1 -C 10 )-alkylsulfinyl, (C 1 -C 10 )-alkylsulfonyl, (C 1 -C 10 -alkyl, and (C 1 -C 10 )-alkoxyl; R6 represents a group of formula (I) or (ii) or (iii) or (iv): wherein * indicates the position at which R6 is bonded to formula (I); m=1, 2, or 3; n=1, 2, or 3; A − is a physiologically acceptable anion; R4 is a group of formula (Y) —(CH 2 ) p —P—(CH 2 ) q —W (Y) wherein p is 0 or an integer from 1 to 4; q is 0 or an integer from 1 to 4; P is absent or is selected from the group consisting of O, S, SO, SO 2 , CO, NR5 CH═CH, N(R5)SO 2 , N(R5)COO, N(R5)C(O), SO 2 N(R5), CO(O)N(R5), and C(O)N(R5); W is H or a group selected from the group consisting of (C 1 -C 6 )-alkyl, (C 3 -C 8 )-cycloalkyl, aryl, and heteroaryl, each of which may be optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (═O), SH, NO 2 , CN, CON(R5) 2 , COOH, NH 2 , NHCOR5, CO 2 R5, (C 1 -C 10 )-alkoxycarbonyl, (C 1 -C 10 )-alkylsulfanyl, (C 1 -C 10 )-alkylsulfinyl, (C 1 -C 10 )-alkylsulfonyl, (C 1 -C 10 )-alkyl, and (C 1 -C 10 )-alkoxyl; R5 is H or a group selected from the group consisting of (C 1 -C 10 )alkyl, (C 1 -C 6 )alkylhalo, (C 2 -C 6 )alkynyl, (C 2 -C 6 )alkenyl, (C 3 -C 7 )cycloalkyl, (C 3 -C 7 )cycloalkyl-(C 1 -C 6 )alkyl, heteroaryl, (C 1 -C 6 )alkyl-heteroaryl, and aryl, each of which may be optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (═O), SH, NO 2 , CN, CONH 2 , COOH, (C 1 -C 10 )-alkoxycarbonyl, (C 1 -C 10 )-alkylsulfanyl, (C 1 -C 10 )-alkylsulfinyl, (C 1 -C 10 )-alkylsulfonyl, (C 1 -C 10 )-alkyl, and (C 1 -C 10 )-alkoxyl; or a pharmaceutically acceptable salt thereof.