Patent ID: 7265130

Claim:
A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula (I): wherein R 1 is optionally substituted lower alkyl or optionally substituted cycloalkyl, R 2 is hydrogen or lower alkyl, and R 1 and R 2 taken together may form lower alkylene, n is 1 or 2, R 3 , R 4 , R 5 and R 6 are each independently hydrogen or lower alkyl, is optionally substituted cycloalkylene or optionally substituted bicycloalkylene, provided that is not and p and q are each independently 0 or 1, R 7 is hydrogen or lower alkyl, and Z is optionally substituted phenyl, optionally substituted phenyl fused with a nonaromatic ring selected from cyclopentane, cyclopentene or cyclohexane; optionally substituted naphthyl, optionally substituted anthryl, optionally substituted biphenyl or a fused heterocyclyl consisting of two rings, selected from the group consisting of indolyl, isoindolyl, indazolyl, indolizinyl, indolinyl, isoindolinyl, quinolyl, isoquinolyl, cinnolinyl, phthalazinyl, quinazolinyl, naphthyridinyl, quinoxalinyl, purinyl, pteridinyl, benzopyranyl, benzimidazolyl, benzisoxazolyl, benzoxazolyl, benzoxadiazolyl, benzisothiazolyl, benzothiazolyl, benzothiadiazolyl, benzofuryl, isobenzofuryl, benzothienyl, benzotriazolyl, imidazopyridyl, triazolopyridyl, imidazothiazolyl, pyrazinopyridazinyl, tetrahydroquinolyl and tetrahydrobenzothienyl; or a pharmaceutically acceptable salt thereof.