Patent ID: 7091231

Claim:
A compound of the formula or a pharmaceutically acceptable salt or a prodrug thereof, wherein a dashed line represents the presence or absence of a covalent bond; Y is a carboxylic acid, sulfonic acid, or phosphonic acid; or an amide or ester thereof having from 0 to 12 carbon atoms; or Y is a hydroxymethyl, or tetrazolyl functional group provided that when X is C═O, Y is not an amide of a carboxylic acid; A is —(CH 2 ) 6 —, cis—CH 2 CH═CH r —(CH 2 ) 3 —, or —CH 2 C≡C—(CH 2 ) 3 —, wherein 1 or 2 carbon atoms may be substituted with S or O; or A is —(CH 2 ) m —Ar—(CH 2 ) o — wherein Ar is substituted or unsubstituted phenyl or monocyclic heteroaryl, the sum of m and o is from 1 to 4, and wherein one CH 2 may be substituted with S or O; X is C═O, CHF, CF 2 , CHCl, or CHOH; wherein if X is CHOH, then OH is in the β-configuration; R is a hydrocarbyl or a hydroxyhydrocarbyl moiety having from 1 to 12 carbon atoms; D is independently a moiety having from 1 to 6 non-hydrogen atoms; and n is an integer from 0 to 4.