Patent ID: 7070810

Claim:
A vesicle having an interior, an exterior, and a wall, wherein the wall comprises one or more layers, wherein each layer comprises a substituted fullerene having structure I: (B) b —C n -(A) a (I) wherein C n is a fullerene moiety comprising n carbon atoms, wherein n is an integer and 60≦n≦240; B is an organic moiety comprising from 1 to about 40 polar headgroup moieties; b is an integer and 1≦b≦5; each B is covalently bonded to the C n through 1 or 2 carbon-carbon, carbon-oxygen, or carbon-nitrogen bonds; A is an organic moiety comprising a terminus proximal to the C n and one or more termini distal to the C n , wherein the termini distal to the C n each comprise —C x H y , wherein x is an integer and 8≦x≦24, and y is an integer and 1≦y≦2x+1; a is an integer, 1≦a≦5; 2≦b+a≦6; and each A is covalently bonded to the C n through 1 or 2 carbon-carbon, carbon-oxygen, or carbon-nitrogen bonds, wherein the vesicle wall comprises at least about 50 mol % the substituted fullerene; and, wherein the interior of the vesicle, a portion of the wall between two layers, or both comprise a therapeutic agent.