Patent ID: 8252163

Claim:
A capillary electrophoresis apparatus, comprising an electrophoresis chip comprising a substrate; a capillary channel; and a plurality of liquid reservoirs in communication with each other via the capillary channel, wherein the volume of the liquid reservoirs is from about 10 mm 3 to about 100 mm 3 ; a voltage application unit comprising an electrode in communication with the capillary channel; an absorbance measurement unit; a pre-filter component; an air vent structure; a stray light removing unit; and a position adjustment unit, wherein the apparatus is capable of electrophoretic separation and detection of a sample introduced into the capillary channel wherein the detection is measured by the absorbance measurement unit; wherein the sample comprises hemoglobin that is at least one of hemoglobin A1c, hemoglobin F, hemoglobin A2, hemoglobin S, and hemoglobin C; and wherein the electrophoresis chip surface has been treated with at least one of phosphoric acid, UV radiation, alkali dipping, an inorganic nanomicroparticle coating, graft co-polymerization and corona discharge to minimize adsorption of the sample.