Patent ID: 8735355

Claim:
A method of inhibiting tumor growth, comprising contacting tumor cells with a therapeutically effective amount of a pharmaceutical composition comprising at least one polypeptide fragment of secreted frizzled related protein (sFRP) comprising an amino acid sequence selected from the group consisting of: (i) a polypeptide fragment denoted sFRP-Δ1 having at least 90% sequence identity to the amino acid sequence shown in SEQ ID NO: 5; (ii) a polypeptide fragment denoted sFRP-Δ2 having at least 90% sequence identity to the amino acid sequence shown in SEQ ID NO: 6; (iii) a polypeptide fragment denoted sFRP-Δ3 having at least 90% sequence identity to the amino acid sequence shown in SEQ ID NO: 7; and (iv) a polypeptide fragment denoted sFRP-ΔCRD having at least 90% sequence identity to the amino acid sequence shown in SEQ ID NO: 8.