Patent ID: 8323649

Claim:
A method of treating one or more symptoms of a disease or condition associated with elevated interleukin 6 (IL-6), comprising administration of an anti-human IL-6 antibody or antibody fragment to a subject in need thereof, wherein the anti-human IL-6 antibody or antibody fragment comprises: a variable light (VL) region comprising the VL complementarity regions CDR1, CDR2 and CDR3, respectively having the sequences of SEQ ID NO:4, 5 and 6, and a variable heavy (VH) region comprising the VH complementarity regions CDR1, CDR2 and CDR3, respectively having the sequences of SEQ ID NO:7, 8 or 120 and 9; and wherein said anti-human IL-6 antibody or antibody fragment specifically binds to human IL-6 and antagonizes one or more activities associated with IL-6 in vivo, thereby treating one or more symptoms of said disease or condition associated with elevated interleukin 6 (IL-6).