Patent ID: 7456279

Claim:
A process for perparing a substituted quinolone according to Formula I: wherein: R 1 is C 1 -C 4 alkyl; R 2 is C 1 -C 4 alkyl or C 3 -C 6 cycloalkyl; R 4 and R 5 are each independently selected from a group consisting of amino, C 1 -C 4 alkylamino, protected amino, and C 1 C 4 alkyl; and n is 1 or 2; said process comprising: the step of reacting a compound of Formula II with compound of Formula III in the presence of a suitable base at about 20° C. to about 80° C., followed by hydrolysis: wherein: R 3 is acetoxy; and R 1 ,R 2 ,R 4 ,R 5 , and n are as defined for Formula I above.