Patent ID: 6867185

Claim:
A compound of formula I, including pharmaceutically acceptable salts thereof, wherein: (a) R 1 is C 1-6 alkyl or unsubstituted C 3-7 cycloalkyl; (b) R 2 is H, halo, C 1-6 alkyl, C 1-6 alkoxy, C 3-6 cycloalkoxy, C 6 or 10 aryl or heterocycle; wherein heterocyle is a five-, six-, or seven-membered saturated or unsaturated heterocycle containing from one to four heteroatoms selected from nitrogen, oxygen and sulfur; said aryl or heterocycle being substituted with R 24 ; wherein R 24 is H, halo, C 1-6 alkyl, —N(R a )(R b ), —N (R a )C(O)(OR d ), —N(R a )C(O)(R b ), —NHC(O)(R a )(R c ) or —N(R a )SO 2 R b ; wherein R a and R b are independently H, C 1-6 alkyl or C 3-6 cycloalkyl; R c is H, C 1-6 alkyl, C 3-6 cycloalkyl or C 1-6 alkoxy; R d is C 1-6 alkyl or C 3-6 cycloalkyl; (c) R 3 is H, halo, CF 3 , C 1-6 alkoxy or C 3-6 cycloalkoxy; (d) R 4 is NH 2 , or —NH—R 31 ; wherein R 31 is —C(O)—R 32 , C(O)—NHR 32 or C(O)—OR 32 ; wherein R 32 is C 1 -C 6 alkyl optionally substituted with halo, —(CH 2 ) p —C 3-7 cycloalkyl or a tetrahydrofuran ring linked through the C3 or C4 position of the ring; wherein p is 0-6; (e) R 5 is H; and (f) Q is a three to nine atom saturated or unsaturated alkylene chain optionally containing one to three heteroatoms independently selected from O or S(O) m ; wherein m is 0, 1 or 2.