Patent ID: 7253282

Claim:
A compound of formula (I) wherein R 1 is hydrogen, lower-alkyl, fluoro-lower-alkyl, lower-alkyl-carbonyl, fluoro-lower-alkyl-carbonyl, aryl-lower-alkyl, cycloalkyl-lower-alkyl, cycloalkyl-carbonyl or cycloalkyl-lower-alkyl-carbonyl; R 2 is hydrogen or lower-alkyl; R 3 is lower-alkyl, aryl-lower-alkyl, heterocyclyl-lower-alkyl or lower-alkoxy-carbonyl, or, if X is not a single bond, or, if X is a single bond and m is not 0, R 3 can also be hydroxy; R 4 is aryl or heterocyclyl; X is a single bond, SO 2 , CO, C(O)O or C(O)N(R 5 ); R 5 is hydrogen, lower-alkyl, aryl, heterocyclyl, aryl-lower-alkyl or heterocyclyl-lower-alkyl; m is 0, 1, 2 or 3; n is 0 or 1; and pharmaceutically acceptable salts and esters thereof.