Patent ID: 8538515

Claim:
An internal medical device comprising: (a) electrodes that are adapted to be positioned in a body lumen that is created by surrounding tissue upon implantation or insertion of said medical device in a subject, said electrodes further being adapted to have said surrounding tissue positioned between them upon deployment of said medical device within said body lumen, (b) a power source adapted to apply a voltage across said electrodes, thereby generating an electric field having a vector that is directed into said surrounding tissue, and (c) a therapeutic agent source adapted to introduce a therapeutic agent into said electric field, wherein said body lumen is a lumen of the cardiovascular system that comprises a main vessel and a side vessel, wherein said device comprises a main balloon having a cylindrical central portion that is configured to occupy said main vessel upon deployment and a side balloon extending from a lateral surface of said central cylindrical portion that is configured to occupy said side vessel upon deployment, wherein said electrodes comprise a main balloon electrode disposed upon said main balloon and a side balloon electrode disposed upon said side balloon, and wherein said therapeutic agent source comprises a polymeric layer that comprises a charged drug and is disposed over the main balloon, the side balloon, or both, wherein the main balloon electrode is adapted to be biased at a first potential, and the side balloon electrode is adapted to be biased at a second potential that is different from the first potential such that an electric field is generated between the electrodes that urges the charged drug out of the polymeric layer and into said surrounding tissue.