Patent ID: 8436044

Claim:
A pharmaceutical composition or a combination drug, comprising as active ingredients thereof, (a) a coordination compound composed of a block copolymer represented by the following formula I or formula II and cisplatin coordinated in the block copolymer: wherein, R 1 independently represents a hydrogen atom or an alkyl group that may be substituted by a functional group or substituent, A independently represents NH, CO, R 5 (CH 2 ) p R 6 or a direct bond, R 5 represents O, OCO, OCONH, NHCO, NHCOO, NHCONH, CONH or COO, R 6 represents NH or CO, p represents an integer of 1 to 6, R 2 independently represents a hydrogen atom, alkaline metal, alkyl group or aralkyl group, R 3 independently represents a hydrogen atom, hydroxyl group or hydrophobic residue, m independently represents an integer of 40 to 450, and n independently represents an integer of 20 to 80, and (b) gemcitabine hydrochloride which is separate from any polymeric carrier wherein the cisplatin coordination compound is at an amount of at least 5 mg/kg and the gemcitabine hydrochloride is at an amount of at least 75 mg/kg.