Patent ID: 7838539

Claim:
A method for treating a disorder in a mammal having the disorder, the method comprising administering to the mammal a substantially pure nicotine receptor agonist in a therapeutically effective amount effective to stimulate long-term hematopoietic stem cells (LTHSCs) and short-term hematopoietic stem cells (STHSCs) or progeny thereof to proliferate, wherein the disorder is neutropenia, leukopenia, or an acquired immunodeficiency, wherein the acquired immunodeficiency results from radiation, chemotherapy, or a viral infection other than human immunodeficiency virus, and wherein said administering is effective to increase the number of long-term and short-term hematopoietic stem cells or progeny thereof in the bloodstream of the mammal, to increase the number of long-term and short-term hematopoietic stem cells or progeny thereof in the peripheral circulation of the mammal, or to stimulate incorporation of long-term and short-term hematopoietic stem cells or progeny thereof into a treatment site in the mammal.