Patent ID: 8017777

Claim:
A process for the preparation of compound 8 according to the following reaction scheme: wherein: R 0 and R 8 are independently selected from the group consisting of hydrocarbyl, and substituted hydrocarbyl; R 1 , R 7 and R 8a are independently selected from the group consisting of hydrogen, hydrocarbyl, and substituted hydrocarbyl; R 2 , R 3 , R 4 , R 5 , and R 6 are independently selected from the group consisting of hydrogen, halogen, OR b , hydrocarbyl, and substituted hydrocarbyl, or R 2 and R 3 may together form {−}=O; R a is a hydroxyl protecting group; R b is selected from the group consisting of hydrogen, hydrocarbyl, and substituted hydrocarbyl; M is selected from Group IA metal salts, and Group IIA metal salts; X, and X 2 are independently selected from the group consisting of bromide, and chloride; X 1 is bromide or chloride when R 4 is hydrogen, and X 1 is R 4 when R 4 is not hydrogen; and Y is selected from the group consisting of oxygen, sulfur, and nitrogen.