Patent ID: 8629157

Claim:
A compound of the formula (I) X is NH; Ar 1 is chosen phenyl, benzoxazolyl, benzothiazolyl, benzimidazolyl, dioxanyl, tetrahydrofuranyl, oxazolyl, isoxazolyl, thiazolyl, pyrazolyl, pyrrolyl, imidazolyl, thienyl, thiadiazolyl, triazolyl, thiomorpholinyl, 1,1-Dioxo-1λ 6 -thiomorpholinyl, morpholinyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, triazinyl, pyrrolidinyl, piperidinyl, piperazinyl, purinyl, quinolinyl, Dihydro-2H-quinolinyl, isoquinolinyl, quinazolinyl, indazolyl, indolyl, isoindolyl, benzofuranyl, benzopyranyl and benzodioxolyl each optionally substituted by 1-3 C 1-6 alkyl, C 1-6 alkoxy, CN, halogen, NO 2 , —S(O) 2 —C 1-3 alkyl, —CO 2 —C 1-4 alkyl, C(O)—NH(C 1-3 alkyl), —C(O)—N(C 1-3 alkyl) 2 , —N(C 1-3 alkyl), —N(C 1-3 alkyl)—C(O)—C 1-4 alkyl, —N(C 1-3 alkyl)—S(O) 2 —C 1-3 alkyl, morpholinyl or piperazinyl; Ar 2 is chosen from benzoxazolyl, benzothiazolyl, benzimidazolyl, oxazolyl, isoxazolyl, thiazolyl, pyrazolyl, pyrrolyl, imidazolyl, thienyl, thiadiazolyl, triazolyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, triazinyl, quinolinyl, isoquinolinyl, quinazolinyl, indazolyl, thieno[2,3-d]pyrimidinyl, indolyl, isoindolyl and benzofuranyl, each optionally substituted by 1-3 C 1-6 alkyl, cyclopropyl, cyclohexyl, phenyl, CN, halogen, pyrimidinyl, acetyl or oxo (═O); L 1 is a bond; L 2 is chosen from a bond, —CH 2 — and —CH 2 —CH 2 —; wherein L 2 where possible is optionally substituted by halogen or C 1-3 alkyl; R 1 is chosen from oxo (═O ); m is 0, 1 or 2; wherein each Ar 1 and Ar 2 , or the substituents thereof are optionally partially or fully halogenated; the stereogenic carbon indicated with an arrow is in the (S) configuration; or a pharmaceutically acceptable salt thereof.