Patent ID: 8110657

Claim:
A chimeric peptide for stimulating an immune response to HER-2 protein comprising a HER-2 B cell epitope, a T helper (Th) epitope, and a linker joining the HER-2 B cell epitope to the Th epitope, wherein: the HER-2 B cell epitope consists of a sequence selected from the group consisting of: ALVTYNTDTFESMPNPEGRYT, SEQ ID NO: 5; the Th epitope comprises a sequence selected from the group consisting of: NSVDDALINSTIYSYFPSV, SEQ ID NO: 13; PGINGKAIHLVNNQSSE, SEQ ID NO: 14; QYIKANSKFIGITEL, SEQ ID NO: 15; NNFTVSFWLRVPKVSASHLE, SEQ ID NO: 16; LSEIKGVIVHRLEGV, SEQ ID NO: 17; FFLLTRILTIPQSLN, SEQ ID NO: 18; and TCGVGVRVRSRVNAANKKPE, SEQ ID NO: 19; and the linker comprises a sequence that is from 1 to 15 amino acids in length.