Patent ID: 7291614

Claim:
A process for preparation of S—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl amine (II) from R—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl azide (III) by catalytic hydrogenation comprising: (a) combining R—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl azide (III) with an organic solvent other than ethyl acetate selected from the group consisting of: C 6 -C 12 aromatic hydrocarbons, mono-,di-, or tri-C 1 -C 4 alkyl substituted or unsubstituted benzenes, and chlorinated aromatic hydrocarbons to obtain a mixture; and (b) inducing catalytic hydrogenation of the said azide (III) mixture to obtain S—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl amine (II).