Patent ID: 8071787

Claim:
A compound of the following formula: wherein each of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 , independently, is H, halo, alkyl, cyano, nitro, amino, boronic acid, boronic ester, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; T is C(R a R b ), NR c , O, or S; in which each of R a and R b , independently, is H, alkyl, halo, cyano, nitro, amino, alkoxy, hydroxy, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and R c is H, alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; X is C(R d R e ), NR f , O, or S; in which each of R d and R e , independently, is H, alkyl, halo, cyano, nitro, alkoxy, hydroxy, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and R f is H, alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and R is alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, â€”C(O)OR g , or â€”C(O)NR h R i ; in which R g is alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and each of R h and R i , independently, is H, alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, arylalkyl, or hydroxy, or R h and R i together with the N atom to which they are attached form a 5 or 6 membered ring, optionally substituted with alkyl, aryl, halo, hydroxy, alkoxy, nitro, amino, alkoxycarbonyl, or carboxy; and optionally fused with a 3-8 membered aromatic or non-aromatic ring containing 0, 1, 2, or 3 heteroatoms.