Patent ID: 7345190

Claim:
A dual prodrug compound or a pharmaceutically acceptable salt thereof of Formula 1, wherein A is a single bond, —O—, or —CH 2 —; m and n vary from 1 to 15; p and q vary from 0 to 1; B is —CR 3 R 4 ; D is selected from the group consisting of —CO 2 R 5 —OR 6 , —OCOR 7 , —SO 3 R 8 , —SO 2 NH 2 , —OPO(OR 9 )(OR 10 ), —OPO(OR 9 )(NH 2 ), —OPO(OR 9 )—O—PO(OR 10 )(OR 11 ), wherein R 1 to R 4 are independently selected from C 1 -C 6 alkyl; and R 5 to R 11 are independently selected from the group consisting of hydrogen; C 1 -C 6 alkyl; C 3 -C 6 cycloalkyl; C 2 -C 6 alkenyl; C 6 alkynyl; C 5 -C 10 aryl unsubstituted or substituted with C 1 -C 6 alkyl, hydroxyl, C 1 -C 6 alkoxyl, 1,3-dioxolanyl, cyano, halo, nitro, trihaloalkyl, carboxyl, C 1 -C 6 acyl, C 1 -C 6 hydroxyalkyl, amino, C 1 -C 6 alkylamino, C 1 -C 6 dialkylamino, C 1 -C 6 acylamino, and C 1 -C 6 alkxoylcarbonyl; C 5 -C 6 arylalkyl unsubstituted or substituted with C 1 -C 6 alkyl, hydroxyl, C 1 -C 6 alkoxyl, 1,3-dioxolanyl, cyano, halo, trihaloalkyl, carboxyl, C 1 -C 6 acyl, C 1 -C 6 hydroxyalkyl, amino, C 1 -C 6 alkylamino, C 1 -C 6 dialkylamino, and C 1 -C 6 alkxoylcarbonyl; C 1 -C 6 carboxyalkyl; C 1 -C 6 acylamino; C 1 -C 6 sulfonatoalkyl; C 1 -C 6 sulfamylalkyl; and C 1 -C 6 phosphonatoalkyl.