Patent ID: 8710044

Claim:
A compound of Formula (I) and pharmaceutically acceptable salts, thereof, wherein: X is N, Y is NH, O or absent, R 1 is L 1 -R 4 -L 2 -R 5 or L 1 -R 4 , R 2 is A, Hal, OH, OA, SH, CN, NH 2 , NO 2 , NHA, NH-L 1 -Ar, NHCOA, NHCO-L- 1 -Ar, NHSO 2 A, NHSO 2 -L 1 -Ar, NHCONHA, NHCONH-L 1 -Ar, L 1 -Ar, O-L 1 -Ar, L 1 -R 4 , L 1 is a single bond, methylene, or methyl substituted methylene, wherein the methylene, or the methyl group of the methyl substituted methylene may be unsubstituted or mono- or disubstituted with Hal, OH, CN, NH 2 , NH(LA), N(LA) 2 , NO 2 , COOH, N 3 , ethenyl or ethynyl, and/or monosubstituted with R 4 , and in which one or two CH 2 groups may be replaced by an O or S atom or by an —NH—, —N(LA)-, —CONH—, —N(LA)COO—, —SO 2 — or —NHCO— group, R 3 is H, A, Hal, OH, COOH, SH, NH 2 , NO 2 or CN, R 4 , R 5 each, independently of one another, are Ar, or cyclic A which may be mono- or disubstituted by Hal or LA, L 2 is —NHCO—, —NHCOO—, —NHCONH—, —NHCONA-, —NHCOA—, —O—, —S—, —NH—, —NHSO 2 —, —SO 2 NH—, —CONH—, —CONHCONH—, —NHCONHCO—, or -A-, Ar is a mono- or bicyclic aromatic homo- or heterocycle having 0, 1, 2, 3 or 4 N, O and/or S atoms and 5, 6, 7, 8, 9, or 10 skeleton atoms, which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, A, OH, SH, OA, NH 2 , NHA, NA 2 , NO 2 , CN, OCN, SCN, COOH, COOA, CONH 2 , CONHA, CONA 2 , NHCOA, NHCONHA, NHCONH 2 , NHSO 2 A, CHO, COA, SO 2 NH 2 , SO 2 A and/or SO 2 Hal, and in which a ring N-atom may be substituted by an O-atom to form an N-oxide group, and in which in the case of a bicyclic aromatic cycle on of the two rings may be partly saturated, A is unbranched or branched linear or cyclic alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 C atoms, in which one or two CH 2 groups may be replaced by an O or S atom and/or by an —NH—, —CO—, —NHCOO—, —NHCONH—, —N(LA)-, —CONH—, —NHCO— or —CH═CH— group, and in which 1-3 H atoms may be replaced by Hal, and in which one or two CH 3 groups may be replaced by OH, SH, NH 2 , NH(LA), N(LA) 2 , NHCOOH, NHCONH 2 or CN, LA is unbranched or branched, linear alkyl having 1, 2, 3 or 4 C atoms, wherein 1, 2 or 3 H atoms may be replaced by Hal, Hal is F, Cl, Br or I.