Patent ID: 8501941

Claim:
A process for preparing a compound of the formula Xa: R 1 is (C 3-8 )cycloalkyl; and R 2 is hydrogen, or is selected from the group consisting of (C 1-8 )alkyl, halo(C 1-8 )alkyl, (C 3-8 )alkenyl, (C 3-8 )alkenyl(C 1-8 )alkyl, (C 3-8 )alkynyl, (C 3-8 )alkynyl(C 1-8 )alkyl, (C 1-8 )alkoxy, (C 3-8 )cycloalkyl(C 1-8 ) alkyl-,(C 4-10 ) heterocyclyl, (C 4-10 )heterocyclyl(C 1-8 )alkyl-, (C 6-10 )aryl, (C 6-10 )arloxy, (C 6-10 )aryl(C 1-8 ) alkyl-, (C 5-10 )heteroaryl and (C 5-10 )heteroaryl(C 3-8 )alkyl-; comprising: a) contacting a compound of the formula XII: with a compound of the formula NC—CH 2 —COOH with a dehydrating agent; b) hydrolyzing the resulting reaction mixture to form a mixture of the compound of the formulae Xa and Xb; and c) separating the compound of the formula Xa from the formula Xb.