Patent ID: 7524869

Claim:
A taxane having the formula R 2 is acyloxy; R 7 is hydroxy; R 9 is keto, hydroxy, or acyloxy; R 10 is R 10a COO—; R 10a is hydrocarbyl, substituted hydrocarbyl, or heterocyclo wherein said hydrocarbyl or substituted hydrocarbyl contains carbon atoms in the alpha and beta positions relative to the carbon atom of which R 10a is a substituent and said heterocyclo is bonded to the carbonyl carbon of R 10a COO- through a ring carbon atom; R 14 is hydrogen or hydroxy; X 3 is heterocyclo; X 5 is —COX 10 , —COOX 10 , or —CONHX 10 ; X 10 is hydrocarbyl, substituted hydrocarbyl, or heterocyclo; and Ac is acetyl.