Patent ID: 6890916

Claim:
A compound of formula I wherein (a) one of Y 1 and Y 2 is N, which is bound to Y 4 , and the other of Y 1 and Y 2 is CO, CS, SO, or SO 2 and Y 4 is CH 2 ; (b) one of Y 1 and Y 2 is N, which is bound to Y 4 , and the other of Y 1 and Y 2 is CH 2 and Y 4 is CO, CS, SO or SO 2 ; or (c) one of Y 1 and Y 2 is N, which is bound to Y 4 , and the other of Y 1 and Y 2 is CH 2 and Y 4 is CH 2 ; Y 3 is Z-CH 2 , CH 2 -Z or CH 2 CH 2 , and Z is O or S; provided that when Y 1 is N, Y 3 may not be Z-CH 2 ; W is a bond or an O, S, CO, CS, SO or SO 2 group; n is 0-5, m is 0-5 and m+n is 1 to 10; provided that when W is O or S, then n≧2 and m≧1; when W is CO, CS, SO or SO 2 , then n≧1 and m≧1; X is C or CH provided that when X is C, the dotted line indicates a bond, and when X is CH, the dotted line is absent; R 1 —R 9 are independently selected from hydrogen, halogen, cyano, nitro, amino, hydroxy, C 1-6 -alkyl-amino, di-C 1-6 -alkyl-amino, C 1-6 -alkyl, C 2-6 -alkenyl, C 2-6 -alkynyl, C 1-6 alkoxy, C 1-6 -alkylthio, C 1-6 -alkyl substituted with hydroxy or thiol, C 3-8 -cycloalkyl, C 3-8 -cycloalkyl-C 1-6 -alkyl, acyl, thioacyl, aryl, trifluoromethyl, trifluoromethylsulfonyl, and C 1-6 alkylsulfonyl; R 10 is hydrogen, C 1-6 -alkyl, C 2-6 -alkenyl, C 2-6 -alkynyl, C 1-6 -alkyl substituted with hydroxy or thiol, C 3-8 -cycloalkyl, C 3-8 -cycloalkyl-C 1-6 -alkyl, aryl, aryl-C 1-6 -alkyl, acyl, thioacyl, C 1-6 -alkylsulfonyl, trifluoromethylsulfonyl or arylsulfonyl, or a pharmaceutically acceptable acid addition salt thereof.