Patent ID: 8142815

Claim:
An injectable composition suitable for dermal augmentation in a mammal which comprises biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres autologous cells associated with surfaces of at least a portion of the microspheres prior to injection, and a biocompatible carrier, wherein said composition is injectable through needles of about 30 gauge or smaller, wherein said microspheres swell to a predetermined size after injection, wherein there is no aggregation or clumping of the microspheres prior to and during injection, wherein the microspheres comprise a polymer selected from: sodium acrylate polymer, acrylamide polymer, acrylamide derivative polymer or copolymer, sodium acrylate and vinyl alcohol copolymer, vinyl acetate and acrylic acid copolymer, vinyl acetate and methyl maleate copolymer, isobutylene-maleic anhydride crosslinked copolymer, starch-acrylonitrile graft copolymer, crosslinked sodium polyacrylate polymer, crosslinked polyethylene oxide, or mixtures thereof, wherein the autologous cells are selected from: fat cells, muscle cells, subcutaneous cells, dermal cells, epidermal cells, or combinations thereof, and wherein the microspheres appear smooth under magnification of up to 1000 times.