Patent ID: 8100921

Claim:
A method for reducing gastric volume comprising: accessing an external surface of a wall of the gastrointestinal tract at a first location; positioning a distal end of at least one device in proximity to the first location; manipulating a first tissue engagement mechanism of said device to engage tissue by piercing the external surface of the wall of the gastrointestinal tract at a first tissue site and manipulating a second tissue engagement mechanism of said device to engage tissue by piercing the external surface of the wall of the gastrointestinal tract at a second tissue site spaced apart from the first tissue site; manipulating said device while the first and second tissue sites are both engaged to approximate said engaged, spaced apart tissue sites to create at least one invaginated tissue fold extending from the approximated tissue sites into an interior space of the gastrointestinal tract; and fastening the approximated tissue sites to one another to secure the tissue fold.