Patent ID: 8546433

Claim:
A method for treating or managing cancer associated with Axl catalytic activity in a patient in need thereof, wherein the method comprises administering to the patient a therapeutically effective amount of an Axl inhibitor selected from 1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N 3 -(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulene-2-yl)-1H-1,2,4-triazole-3,5-diamine, an isolated stereoisomer or mixture thereof or a tautomer or mixture thereof, or a pharmaceutically acceptable salt or N-oxide thereof; and a therapeutically effective amount of one or more chemotherapeutic agents.