Patent ID: 8598355

Claim:
A compound of the formula (I) or a salt thereof: wherein ring D is a group of the formula (II), R 45 is —X 1 —B 5 , R 46 is —H, halogen, C 1-6 alkyl which may be substituted with one or more halogens, or —O—C 1-6 alkyl, V and W are CH, X 1 is methylene, B 5 represents (i) a bicyclic hetero ring which may be substituted with one or more groups selected from the group consisting of halogen and C 1-6 alkyl, or (ii) monocyclic aryl, a monocyclic hetero ring, or C 3-10 monocyclic cycloalkyl, each of which is substituted with the same or different 1 to 5 groups selected from R 5 , R 5 is selected from the group consisting of halogen, —OH, —O—(C 1-6 alkyl), —O—(C 1-6 alkylene)-O—(C 1-6 alkyl), aryl which may be substituted, a hetero ring which may be substituted, (C 1-6 alkylene)-aryl, (C 1-6 alkylene)-hetero ring, —O—(C 1-6 alkylene)-aryl, and —O—(C 1-6 alkylene)-hetero ring, ring E is cyclohexane-1,4-diyl, R 1 and R 2 are both H, Y is CH, Z is a bond, and R 3 is —CO 2 H.