Patent ID: 7432281

Claim:
A compound having a formula: or a pharmaceutically acceptable salt, or a stereoisomer thereof, wherein: each of W, X, Y and Z is independently selected from N and CR 4 ; L is —(CR 5 ═CR 6 )—; G is C═O; R 1 is substituted or unsubstituted cycloheteroalkyl, or heteroaryl; R 2 is hydrogen; R 3 is CF 3 , n-propyl, or a group of formula: wherein each of R 2′ is hydrogen or alkyl provided at least two of R 2′ are alkyl; and wherein two R 2′ that are alkyl may join together to form a cycloalkyl ring of 3-8 atoms; each R 4 is independently hydrogen, alkyl, substituted or unsubstituted alkyl, acyl, acylamino, alkylamino, alkylthio, alkoxy, alkoxycarbonyl, alkylarylamino, arylalkyloxy, amino, aryl, arylalkyl, sulfinyl, sulfonyl, sulfanyl, aminosulfonyl, arylsulfonyl, sulfo, dihydroxyphosphoryl, aminohydroxyphosphoryl, azido, carboxy, carbamoyl, carboxyl, cyano, cycloheteroalkyl, dialkylamino, halo, heteroaryloxy, heteroaryl, heteroalkyl, hydroxyl, nitro or thiol; and each of R 5 and R 6 is independently H, halo, or C 1-6 alkyl.