Patent ID: 8614195

Claim:
A compound represented by structural formula (I): or a pharmaceutiacally acceptable salt thereof, wherein: A is selected from the group consisting of V is hydrogen, halo or —OR 1b ; R 1 , R 1a and R 1b are independently selected from the group consisting of hydrogen, C 1-6 alkyl, C 6-10 aryl-C 1-4 alkyl, —C(O)C 6-10 aryl and —C(O)C 1-6 alkyl; R 2 and R 2a , for each occurrence, are independently selected from the group consisting of halo, hydroxy, C 1-6 alkyl, and C 1-6 alkoxy; R 3 is halo, hydroxy, C 1-6 alkyl, haloC 1-6 alkyl, C 3-10 cycloalkyl, C 1-6 alkoxy, or haloC 1-3 alkoxy; R 4 is selected from the group consisting of: R 5 is an amino acid sidechain; R 6 is a C 1-6 alkyl, C 3-10 carbocyclyl, C 3-10 carbocyclyl-C 1-4 alkyl, 3- to 10-membered heterocyclyl, (3- to 10-membered heterocyclyl)-C 1-4 alkyl, C 6-10 aryl, C 6-10 aryl-C 1-4 alkyl, 5- to 10-membered heteroaryl, or (5- to 10-membered heteroaryl)-C 1-4 alkyl; R 7 , for each occurrence, is independently hydrogen, C 1-6 alkyl, C 3-10 carbocyclyl, C 3-10 carbocyclyl-C 1-4 alkyl, 3- to 10-membered heterocyclyl, (3- to 10-membered heterocyclyl)-C 1-4 alkyl, C 6-10 aryl, C 6-10 aryl-C 1-4 alkyl, 5- to 10-membered heteroaryl, or (5- to 10-membered heteroaryl)-C 1-4 alkyl; n is 0, 1, 2, or 3; and q is 0, 1, or 2.