Patent ID: 7862823

Claim:
A vaccine composition comprising a dose of â€œnâ€ conjugates C1 to Cn, wherein (a) each conjugate comprises (i) a polysaccharide S1 to Sn from a Streptococcus pneumoniae serotype/serogroup, respectively, and (ii) a carrier protein P1 to Pn, respectively; (b) â€œnâ€ is a number equal to or greater than 10; (c) the polysaccharides S1 to Sn are identical or there are from 2 to â€œnâ€ different polysaccharides; and (d) the carrier proteins P1 to Pn are selected independently from a group consisting of â€œmâ€ carrier proteins, wherein â€œmâ€ is a number equal to or greater than 2; (e) at least one of P1 to Pn is Dt and at least one of P1 to Pn is Tt; and (f) the amount of conjugated Dt protein is less than or equal to 60 Î¼g/dose and the amount of conjugated Tt protein in the composition is less than or equal to 25 Î¼g/dose.