Patent ID: 7173047

Claim:
A compound of formula (I): and pharmaceutically acceptable derivatives thereof wherein: R 1 is selected from the group consisting of H, halogen, C 1-6 alkyl, Sâ€”C 1-6 alkyl, C 1-6 alkoxy, OCF 3 , OCH 2 CF 3 , O-cyclopropyl, OCH 2 -cyclopropyl, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl) 2 , NO 2 , OH, CH 2 OC 1-6 alkyl and CH 2 OH; R 2 each independently selected from C 1-4 alkyl; R 3 is H or O; R 4 is H or C 1-6 alkyl; R 5 is selected from the group consisting of C 1-6 alkyl, phenyl, phenyl substituted by one or more R 6 , naphthyl, phenylC 1-6 alkyl, pyridyl, oxazolyl, isoxazolyl, isoxazolyl substituted with one or two C 1-6 alkyl, thiophenyl, C 1-6 alkylCO 2 C 1-6 alkyl, pyrrolyl, furanyl, thiazolyl, isothiazolyl, imidazolyl, pyrazolyl, thiadiazolyl, isothiadiazolyl, indolyl, indazolyl, and benzothiophenyl; R 6 is selected from the group consisting of halogen, C 1-6 alkyl, C 1-6 alkyl substituted by one or more fluorine atoms, C 1-6 alkoxy, cyano, CO 2 H, CO 2 C 1-6 alkyl, OH, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl) 2 , S(O) n C 1-6 alkyl wherein n=0, 1 or 2, CONH 2 , CON(C 1-6 alkyl) 2 , COC 1-6 alkyl, and NHCO(C 1-6 alkyl); R 7 to R 10 each independently are selected from the group consisting of H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkoxy substituted by one or more fluorine atoms, O-cyclopropyl, OCH 2 -cyclopropyl, Sâ€”C 1-6 alkyl, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl) 2 , halogen, NO 2 , OH, CH 2 OC 1-6 alkyl, and CH 2 OH; R 11 is selected from the group consisting of H, OH, halogen, dihalogen, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl) 2 , C 1-6 alkyl, C 1-6 dialkyl, C 1-6 alkoxy, NHCO(C 1-6 alkyl), and â•O; and provided that is a single bond, when R 3 is O, a double bond.