Patent ID: 8227410

Claim:
A method of stimulating wound healing in a mammalian subject in need thereof, the method comprising administering to the subject a polypeptide that stimulates endothelial cell proliferation, wherein the polypeptide is (a) a polypeptide comprising a fragment of the amino acid sequence of SEQ ID NO: 5, wherein said fragment and said polypeptide lack amino acids of SEQ ID NO: 5 that are N-terminal to residue 92 of SEQ ID NO: 5 and lack amino acids that are C-terminal to residue 205 of SEQ ID NO: 5; (b) the polypeptide of (a) that comprises at least amino acids 101-196 of SEQ ID NO: 5; or (c) a polypeptide that lacks amino acids of SEQ ID NO: 5 that are N-terminal to residue 93 of SEQ ID NO: 5 and lack amino acids that are C-terminal to residue 201 of SEQ ID NO: 5.