Patent ID: 7319152

Claim:
A compound of formula II: wherein: R 1 and R 2 are, independently, selected from the group consisting of H, halogen, C 1 to C 6 alkyl, CF 3 , CF 2 CF 3 , C 2 to C 6 alkenyl, C 2 to C 6 alkynyl, C 3 to C 8 cycloalkyl, aryl, and substituted aryl; provided that both R 1 and R 2 are not H; or R 1 and R 2 are fused to form (a) or (b): (a) a carbon-based 3 to 6 membered saturated spirocyclic ring; or (b) a carbon-based 3 to 6 membered spirocyclic ring having in its backbone one or more carbon-carbon double bonds; wherein rings (a)-(b) are optionally substituted by 1 to 3 substituents selected from the group consisting of F, Cl, and C 1 to C 3 alkyl; R 3 is a saturated 5 membered heteroaryl ring containing in its backbone 1 to 3 heteroatoms selected from the group consisting of O, S, SO, SO 2 , and NR C and substituted with 0 to 3 substituents selected from the group consisting of H, halogen, CN, NO 2 , OH, amino, C 1 to C 4 alkyl, C 1 to C 4 alkoxy, C 1 to C 4 alkylamino, C═NOR C , COR D , and NR C COR D ; or R C is absent, H, C 1 to C 4 alkyl, substituted C 1 to C 4 alkyl, CN, or COR D ; R D is H, C 1 to C 4 alkyl, C 1 to C 4 alkoxy, or C 1 to C 4 alkylamino; R 4 is H, halogen, CN, OH, NO 2 , alkoxy, or lower alkyl; R 5 and R 6 are, independently, H, F, or C 1 to C 3 alkyl; or a pharmaceutically acceptable salt thereof.