Patent ID: 7358266

Claim:
A compound of formula I, wherein X is a diradical selected from the group consisting of —O—, —C(Y 1 )(Y 2 )—, and —C(Y 1 )(Y 2 )—C(Y 1 )(Y 2 )—, Y 1 and Y 2 are each radicals independently selected from the group consisting of —H, —F, —Cl and —Br; and Ar is a radical represented by the following structure: wherein R 1 either forms a first fused ring structure with R 2 or is a radical selected from —H and a C1-C6 branched or straight chain alkyl represented by —(C(Z 1 )(Z 2 )(Z 3 )) n , where 1≦n≦6 and Z 1 , Z 2 , and Z 3 are each a radical independently selected from the group consisting of —H, —F, —Cl, —Br, —OH, —NH 2 , and —(C(Z 1 )(Z 2 )(Z 3 )), with a proviso that, if any one of Z 1 , Z 2 , or Z 3 is —OH or —NH 2 , then each of the remaining Z 1 , Z 2 , and Z 3 is independently selected from the group consisting of —H and —(C(Z 1 )(Z 2 )(Z 3 )); R 2 either forms the first fused ring structure with R 1 or forms a second fused ring structure with R 3 or is a radical selected from the group consisting of —H and a C1-C6 branched or straight chain alkyl represented by —(C(Z 1 )(Z 2 )(Z 3 )) n , where 1≦n≦6 and Z 1 , Z 2 , and Z 3 are each a radical independently selected from the group consisting of —H, —F, —Cl, —Br, —OH, —NH 2 , and —(C(Z 1 )(Z 2 )(Z 3 )), with a proviso that, if any one of Z 1 , Z 2 , or Z 3 is —OH or —NH 2 , then each of the remaining Z 1 , Z 2 , and Z 3 is independently selected from the group consisting of —H and —(C(Z 1 )(Z 2 )(Z 3 )); R 3 either forms said second fused ring structure with R 2 is a radical selected from the group consisting of —H and a C1-C6 branched or straight chain alkyl represented by —(C(Z 1 )(Z 2 )(Z 3 )) n , where 1≦n≦6 and Z 1 , Z 2 , and Z 3 are each a radical independently selected from the group consisting of —H, —F, —Cl, —Br, —OH, —NH 2 , and —(C(Z 1 )(Z 2 )(Z 3 )), with a proviso that, if any one of Z 1 , Z 2 , or Z 3 is —OH or —NH 2 , then each of the remaining Z 1 , Z 2 , and Z 3 is independently selected from the group consisting of —H and —(C(Z 1 )(Z 2 )(Z 3 )); said first or second fused ring structure is either an aromatic or heteroaromatic 5- or 6-membered fused ring with or without C1-C6 branched or straight chain alkyl substituents; and the stereogenic center in 15-position can have R or S configuration, or a salt thereof.