Patent ID: 7824611

Claim:
A device for detecting one or more target ligands in a sample, comprising: a nonporous surface comprising one or more particles immobilized to said surface, wherein said particles comprise antibodies or fragments thereof immobilized to said particles, wherein the antibodies or fragments thereof bind specifically to said one or more target ligands, wherein said particle size range is from 1 nm to 5 μm, wherein said surface is a textured surface comprising one or more depressions and/or protrusions extending between 1 nm and 0.5 mm from said surface, wherein one or more of said particles are entrapped within depressions and/or between protrusions on the textured surface, and wherein said assay device comprises a capillary space between said nonporous surface and a second surface spaced at a capillary forming distance from said nonporous surface.