Patent ID: 7585510

Claim:
A method of eliciting in a subject an antibody that binds to the lipopolysaccharide (LPS) inner core of L3, L1, L7, L8, L9, L10, L11 and L12 immunotypes of Neisseria meningitidis comprising administering to said subject an immunogenic composition comprising the LPS inner core of galE mutant of Neisseria meningitidis immunotype L3, wherein the LPS inner core of the galE mutant has the formula: and comprises an LPS inner core epitope wherein a phosphoethanolamine moiety is linked to the 3-position of HepII of the LPS inner core, wherein said epitope is specifically recognized by the monoclonal antibody B5 produced by the hybridoma deposited with the accession number IDAC 260900-1.