Patent ID: 7579345

Claim:
A compound of formula (I) as indicated below: wherein R1 and R2 are, independently, selected from the group consisting of a bond, hydrogen, (C 1 -C 12 )alkyl, (C 2 -C 10 )alkenyl, (C 1 -C 6 )alkyl(C 3 -C 6 )cycloalkyl, (C 1 -C 10 )alkyl-aryl, (C 1 -C 10 )alkyl-OH, (C 1 -C 6 ) alkyl-CN,(C 1 -C 10 )alkyl-halogen, (C 1 -C 6 )alkyl-CF 3 , (C 1 -C 6 )alkyl-alkoxy, and (C 1 -C 6 )alkyl-O—(C 1 -C 6 )alkyl-OCH 3 ; R3 and R4 are, independently, selected from the group consisting of straight or branched chain lower alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 5 to 6 carbon atoms, cycloalkyl-alkyl having 6 to 10 carbon atoms, 2-thienyl, aryl, aryl, heteroaryl having 5 to 6 carbon atoms and N or O as the heteroatom, heteroaryl having 5 to 6 carbon atoms and N or O as the heteroatom, heterocycloalkyl having 5 to 6 carbon atoms and N or O as the heteroatom, and heterocycloalkyl-alkyl having 6 to 10 carbon atoms and N or O as the heteroatom; Y is hydroxy or cyano; and X − is a physiologically acceptable anion associated with the positive charge of the N atom.