Patent ID: 7268232

Claim:
A compound represented by the Formula (I): wherein R 1 and R 2 are each independently selected from the group consisting of hydrogen, lower alkyl, alkenyl, alkynyl, halo, nitro, cyano, hydroxy, amino, lower aminoalkyl, lower alkoxy, aryl, heteroaryl, COOR 4 , CONR 4 R 5 , NHCOR 4 , NHSO 2 R 4 , OCOR 4 , COR 4 , SR 4 , S(O) n R 8 , SO 2 NR 8 R 9 ; R 3 is selected from the group consisting of cyano, nitro, S(O) n R 8 , SO 2 NR 8 R 9 , OSO 2 R 4 , P(O)(OR 4 )(OR 5 ), P(O)(OH)(NR 4 R 5 ), PO(NR 4 R 5 ) 2 , COOR 4 ; ring A is a 6-membered, optionally aromatic, partially saturated or completely saturated carbocycle or heterocycle, containing up to two heteroatoms, selected from the group consisting of NR 6 R 7 , O, SO 2 , S, C═O and C═S; ring B is an optionally substituted tropane; Y 1 and Y 2 are CR 6 R 7 ; R 4 and R 5 are each independently selected from the group consisting of hydrogen, cyano, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted heterocyclylalkyl, optionally substituted arylalkyl, optionally substituted aryl, optionally substituted heteroarylalkyl, optionally substituted heteroaryl; R 6 and R 7 are each independently selected from the group consisting of hydrogen, halo, cyano, hydroxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted heterocyclylalkyl, optionally substituted arylalkyl, optionally substituted aryl, optionally substituted heteroarylalkyl, optionally substituted heteroaryl, OR 4 , NR 4 R 5 , SR 4 , COR 4 , COOR 4 , CONR 4 R 5 , NHCOR 4 , OCOR 4 , CSR 4 , CSOR 4 , CSNR 4 R 5 , NHCSR 4 , OCSR 4 , S(O) n R 4 , SO 2 NR 4 R 5 , OSO 2 R 4 , NHSO 2 R 4 ; R 8 and R 9 are each independently selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted heterocyclylalkyl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl; and n is an integer from 1 to 3; or pharmaceutically acceptable salts, amides, or stereoisomers thereof.