Patent ID: 8431608

Claim:
A compound of Formula (IX): or a pharmaceutically acceptable salt thereof, wherein: R 11 and R 12 are each independently selected from the group consisting of —H, halogen, C 1-8 haloalkyl, —CN, C 1-8 alkyl, C 1-8 alkoxy, aryloxy and aryl-C 1-8 alkoxy; R 13 is selected from the group consisting of aryl, C 3-8 cycloalkyl, aryl-C 1-6 alkyl, C 3-8 cycloalkyl-C 1-8 alkyl, heteroaryl and heteroaryl-C 1-6 alkyl, wherein the aromatic portion of the R 13 group is optionally substituted with from 1-3 R a substituents, each R a is independently selected from the group consisting of halogen, C 1-8 haloalkoxy, C 1-8 alkoxy, C 1-8 haloalkyl, —CN and R b , wherein R b is C 1-8 alkyl optionally substituted with from 1-2 substituents selected from halogen, —CN, —OH, C 1-8 haloalkoxy or C 1-8 alkoxy; or any two adjacent R a substituents together with the atoms to which they are attached form a 5- or 6-membered carbocyclic ring, optionally substituted with a C 1-8 alkyl; R 14 is selected from the group consisting of C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-8 alkyl, aryl, aryl-C 1-8 alkyl, wherein the aromatic portion of the R 14 group is optionally substituted with from 1-3 R e substituents independently selected from the group consisting of halogen, C 1-8 haloalkyl, C 1-8 alkyl, C 1-8 alkoxy, —CN or haloalkoxy, —OH, —OC(O)O—R f , —OC(O)R f , —OC(O)NHR f , —OC(O)N(R f ) 2 , —S(O)R f , —S(O) 2 R f , —SO 2 NH 2 , —S(O) 2 NHR f , —S(O) 2 N(R) 2 , —NHS(O) 2 R f , —NR f S(O) 2 R f , —C(O)NH 2 , —C(O)NHR f , —C(O)N(R f ) 2 , —C(O)R f , —C(O)H, wherein each R f is independently a C 1-8 alkyl; and the cycloalkyl portion of the R 14 group is optionally substituted with from 1-3 substituents selected from halogen, C 1-8 alkyl or optionally fused with a 5- or 6 membered aromatic ring having from 0-2 heteroatoms as ring members selected from N, O or S; R 15 is —H; Z 1 is ═C(R 16 )— and Z 2 is ═C(R 17 )—, wherein R 16 and R 17 are each independently —H, C 1-8 alkyl, halogen, —CN, C 1-8 haloalkyl, C 1-8 haloalkoxy, —OR 9 or —N(R 9 ) 2 , wherein R 9 is independently —H, C 1-8 alkyl or aryl-C 1-8 alkyl; at each occurrence, “alkyl” by itself or as part of another substituent, is an unsubstituted, fully saturated, straight or branched chain hydrocarbon radical; at each occurrence, “cycloalkyl” by itself or as part of another substituent is an unsubstituted, fully saturated, cyclic hydrocarbon radical; and at each occurrence, “aryl” by itself or as part of another substituent is a monovalent monocyclic, bicyclic or polycyclic polyunsaturated aromatic hydrocarbon radical.