Patent ID: 7563813

Claim:
A compound of Formula 1: or a pharmaceutically acceptable salt thereof, wherein R 2 is hydrogen; straight chain alkyl of 1 to 8 carbon atoms; branched chain alkyl of 3 to 12 carbons atoms; alkenyl of 2 to 8 carbon atoms; cycloalkyl or bicycloalkyl of 3 to 12 carbon atoms; heterocycloalkyl or heterobicycloalkyl of 3 to 12 ring atoms having 1 to 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; aryl of 6 to 10 carbon atoms; or heteroaryl of 5 to 10 ring atoms having 1 to 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; R 3 , R 4 , R 5 , and R 6 are, independently, hydrogen; straight chain alkyl of 1 to 8 carbon atoms; branched chain alkyl of 3 to 12 carbons atoms; straight chain alkenyl of 2 to 8 carbon atoms; branched chain alkenyl of 3 to 12 carbons atoms; straight chain alkynyl of 2 to 8 carbon atoms; branched chain alkynyl of 5 to 12 carbons atoms; or cycloalkyl of 3 to 12 carbon atoms; R 1 is a group of the following Formula (2): wherein R 7 is hydrogen; straight chain alkyl of 1 to 8 carbon atoms; branched chain alkyl of 3 to 12 carbons atoms; alkenyl of 2 to 8 carbon atoms; cycloalkyl of 3 to 12 carbon atoms; heterocycloalkyl of 3 to 12 ring atoms having 1 to 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; aryl of 6 to 10 carbon atoms; heteroaryl of 5 to 10 ring atoms having 1 to 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; —C(O)OR; —CONR 2 ; —N(R)COR; or halogen; R is straight chain alkyl of 1 to 8 carbon atoms; or branched chain alkyl of 3 to 12 carbons atoms; R 8 and R 9 are, independently, hydrogen; straight chain alkyl of 1 to 8 carbon atoms; branched chain alkyl of 3 to 12 carbons atoms; alkenyl of 2 to 8 carbon atoms; cycloalkyl of 3 to 12 carbon atoms; heterocycloalkyl of 3 to 12 ring atoms having 1 to 3 heteroatoms independently selected from oxygen, nitrogen, and sulfur; aryl of 6 to 10 carbon atoms; heteroaryl of 5 to 10 ring atoms having 1 to 3 heteroatoms independently selected from nitrogen, oxygen, and sulfur; —C(O)OR; —CONR 2 ; —N(R)COR; or halogen; or R 8 and R 9 , together with the carbon atoms to which they are attached, form a cycloalkyl, heterocycloalkyl, aryl, or heteroaryl group of 5 to 9 atoms, wherein the heterocycloalkyl and heteroaryl groups have 1 to 3 heteroatoms independently selected from oxygen, nitrogen, and sulfur; and W is S.