Patent ID: 8106059

Claim:
A compound of Formula I: wherein: R 1 is —CF 2 X having an absolute stereochemistry of R or S, in which X is hydrogen, fluoro or chloro, or X is alkyl of 1-4 carbon atoms optionally substituted by 1, 2, or 3 substituents selected from the group consisting of fluoro, chloro, and cycloalkyl of 3-8 carbon atoms, which is optionally substituted by 1, 2, or 3 substituents selected from the group consisting of fluoro and chloro; or R 1 , and the carbon to which it is attached, form —C(═O); R 2 is selected from the group consisting of alkyl of 1-6 carbon atoms and cycloalkyl of 3-8 carbon atoms, having an absolute stereochemistry of R or S, each of which is optionally substituted by 1, 2 or 3 groups selected from the group consisting of fluoro, chloro, and cycloalkyl of 3-6 carbon atoms, and R 3 is —CF 2 Y having an absolute stereochemistry of R or S, in which Y is selected from the group consisting of hydrogen, fluoro and chloro, or Y is alkyl of 1-4 carbon atoms optionally substituted by 1, 2, or 3 substituents selected from the group consisting of fluoro, chloro, and cycloalkyl of 3-8 carbon atoms, which is optionally substituted by 1, 2, or 3 substituents selected from the group consisting of fluoro and chloro; or R 3 , and the carbon to which it is attached, form —C(═O); with the proviso that R 1 and R 3 are different; or a pharmaceutically acceptable salt thereof.