Patent ID: 7807668

Claim:
A compound of formula (I) where: W is N, Y is NH or NR 2 and Z is SO or SO 2 or Z is NH or NR 2 and Y is S, SO or SO 2 where R 2 is straight or branched chain C 1 -C 6 alkyl; R 1 is CO 2 H, CO 2 R 2 , CHO, C(═O)R 3 , CN, CONH 2 , CONHR 3 , CON(R 3 ) 2 , CH(OH)(OR 3 ), CH(OR 3 ) 2 , H, halogen, NHCOR 3 , N(COR 3 ) 2 , NH 2 , NHR 3 , N(R 3 ) 2 , NO 2 , OH, OR 3 , SO 2 NHR 3 , SO 2 N(R 3 ) 2 , SO 3 H, SO 2 NH 2 SO 2 R 3 , or R 1 is straight or branched chain C 1 -C 8 alkyl, C 2 -C 8 alkenyl or C 2 -C 8 alkynyl, each of which is optionally substituted with one or more substituents selected from aryl, heteroaryl, halogen, NH 2 , NHR 4 , N(R 4 ) 2 , acyl, OH, OR 4 , or phosphate, or R 1 is a radical of formula (a), (b) or (c) where n is an integer from 1 to 6; where R 3 is straight or branched chain C 1 -C 8 alkyl, C 2 -C 6 alkenyl or C 2 -C 8 alkynyl, aryl or heteroaryl group, optionally substituted with one or more substituents selected from halogen, NH 2 , NHR 4 , N(R 4 ) 2 , OH, OR 4 , acyl or phosphate; and where R 4 is a straight or branched chain C 1 -C 8 alkyl group, or where two R 4 groups together form a cyclopentyl, cyclohexyl, morpholyl, or N-methylpiperazinyl substituent; with indicates a single bond or a double bond; provided that the following compounds are excluded: 3,4-dihydro-2H-naphtho[2,3-b]-1,4-thiazine-5,10-dione; 2,3-dihydro-7-methyl-1H-pyrido[3,2-gl[3,2-g][1,4][1,4)benzothiazine-5,10-dione; 2,3-dihydro-1H-pyrido[3,2-g][1,4]benzothlazine-5,10-dione; 3,4-dihydro-8-(4-methyl-3-pentenyl)-1,1-dioxide-2H-naphtho[2,3-b]-1, 4-thiazine- 5,10-dione; 3,4-dihydro-7-(4-methyl-3-pentenyl)-1,1-dioxide-2H-naphtho[2,3-b]-1, 4-thiazine- 5,10-dione; 3,4-dihydro-1,1-dioxide-2H-naphtho[2,3-b]-1,4-thiazine-5,10-dione; or: a pure compound of formula (II) where: W, Y, Z and R 1 are as defined above; R 5 is H, C 1 -C 6 alkyl or acyl; and indicates a single bond or a double bond; or a pharmaceutically acceptable salt thereof.