Patent ID: 8546563

Claim:
A method of treating pain comprising administering to a patient a therapeutically effective amount of a compound of the formula (I) wherein, R 1 is C 1-10 alkyl, C 3-10 cycloalkyl-C 0-2 alkyl- or heterocycle-C 0-2 alkyl- wherein the heterocycle is chosen from tetrahydropyranyl, tetrahydrofuranyl, dioxanyl, thiomorpholinyl, 1,1-dioxo-1λ 6 -thiomorpholinyl, morpholinyl, piperidinyl, pyrrolidinyl, tetrahydrothienyl, tetrahydrothiopyranyl, 1,1-dioxo-tetrahydrothiopyranyl, imidazolidinyl, pyrazolidinyl or oxetanyl, each R 1 is optionally substituted with 1 to 3 substituents chosen from halogen, C 1-5 alkyl, C 3-10 cycloalkyl, hydroxy or C 1-6 alkoxy; R 2 is hydrogen or C 1-5 alkyl; or R 1 and R 2 together with the N atom to which they are attached form a 3- to 6-membered heterocyclic ring optionally substituted with 1-3 substituents chosen from C 1-10 alkyl, C 1-10 alkoxy, C 3-10 cycloalkyl, hydroxyl, C 1-3 alkylaminocarbonyl, C 1-3 dialkylaminocarbonyl, C 1-3 alkylcarbonyl, C 1-3 alkyl sulfonyl or halogen; R 3 is methyl, ethyl, or isopropyl; R 4 is H or methyl; or R 3 and R 4 together with the carbon they are attached to form a 3-4 membered cycloalkyl ring; R 5 is furanyl, pyranyl, benzoxazolyl, benzothiazolyl, benzimidazolyl, oxazolyl, imidazolyl, thienyl, pyrimidinyl, pyridazinyl, pyrazinyl, triazinyl, isoxazolyl, thiazolyl, thiadiazolyl, oxadiazolyl, pyrazolyl, triazolyl, pyridinyl or benzothiazolyl each optionally independently substituted with 1 to 3 substituents chosen from C 1-6 alkyl, C 1-5 alkoxycarbonyl, cyano or halogen, each R 5 or it's substituents where possible are optionally partially or fully halogenated; or a pharmaceutically acceptable salt thereof.