Patent ID: 7563456

Claim:
A Process for producing a controlled release encapsulated composition having venlafaxine as active ingredient, the process comprising the steps of: A) preparing a non-active core by: wetting sugar crystals in a coating boiler with a diluted solution of sugar in water; powdering the crystal with corn starch to obtain spherical micro granules; drying the spherical micro granulates; classifying the dried spherical micro granulates by granulometry; B) preparing an active core by: placing the dried spherical micro granulates of the previous step in a coating boiler; wetting the dried spherical micro granulates in the coating boiler with PVP dissolved in isopropyl alcohol; powdering the wet spherical micro granulates with powdered venlafaxine HCl; wetting the granulated powder with venlafaxine HCL with additional PVP dissolved in isopropyl alcohol and powdering with talc; drying the granulates; C) applying a coating over the active core, wherein the coating contains at least one of ethyl cellulose, Shellac, or Cellulose Esters; and D) encapsulating the coated active core.