Patent ID: 8822479

Claim:
A method for the treatment of an impairment of learning and/or memory in a human or animal which comprises administering to the human or animal an amount effective for such treatment of a compound of the formula (I): in which R 1 is C 1 -C 8 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl or C 3 -C 8 -cycloalkyl, where C 1 - C 8 -alkyl is optionally substituted by oxo, and where C 1 -C 8 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl and C 3 -C 8 -cycloalkyl are optionally substituted by up to 3 radicals independently of one another selected from the group of C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, hydroxycarbonyl, cyano, amino, nitro, hydroxy, C 1 -C 6 -alkylamino, halogen, trifluoromethyl, trifluoromethoxy, C 6 -C 10 -arylcarbonylamino, C 1 -C 6 -alkylcarbonylamino, C 1 -C 6 -alkylamino-carbonyl, C 1 -C 6 -alkoxycarbonyl, C 6 -C 10 -arylaminocarbonyl, heteroarylamino-carbonyl, heteroarylcarbonylamino, C 1 -C 6 -alkylsulphonylamino, C 1 -C 6 -alkylsulphonyl, C 1 -C 6 -alkylthio, where C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkylamino, C 6 -C 10 -arylcarbonylamino, C 1 -C 6 -alkylcarbonylamino, C 1 -C 6 -alkylaminocarbonyl, C 1 -C 6 -alkoxy-carbonyl, C 6 -C 10 -arylaminocarbonyl, heteroarylaminocarbonyl, heteroarylcarbonylamino, C 1 -C 6 -alkylsulphonylamino, C 1 -C 6 -alkyl-sulphony and C 1 -C 6 -alkylthio are optionally substituted by one to three radicals independently of one another selected from the group of hydroxy, cyano, halogen, trifluoromethyl, trifluoromethoxy, hydroxy-carbonyl and a group of the formula —NR 3 R 4 , where R 3 and R 4 are independently of one another hydrogen or C 1 -C 6 -alkyl, or R 3 and R 4 together with the nitrogen atom to which they are bonded are 5- to 8-membered heterocyclyl, R 2 is phenyl or heteroaryl, where phenyl is substituted by 1 to 3 radicals and heteroaryl is optionally substituted by 1 to 3 radicals in each case independently of one another selected from the group of C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, hydroxycarbonyl, cyano, trifluoromethyl, trifluoromethoxy, amino, nitro, hydroxy, C 1 -C 6 -alkylamino, halogen, C 6 -C 10 -arylcarbonylamino, C 1 -C 6 -alkylcarbonylamino, C 1 -C 6 -alkylaminocarbonyl, C 1 -C 6 -alkoxycarbonyl, C 6 -C 10 -arylaminocarbonyl, heteroarylaminocarbonyl, heteroarylcarbonylamino, C 1 -C 6 -alkylsulphonyl amino, C 1 -C 6 -alkylsulphonyl and C 1 -C 6 -alkylthio, where C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkylamino, C 6 -C 10 -arylcarbonyl-amino, C 1 -C 6 -alkylcarbonylamino, C 1 -C 6 -alkylaminocarbonyl, C 1 -C 6 -alkoxycarbonyl, C 6 -C 10 -arylaminocarbonyl, heteroarylaminocarbonyl, heteroarylcarbonylamino, C 1 -C 6 -alkylsulphonylamino, C 1 -C 6 -alkylsulphonyl and C 1 -C 6 -alkylthio are optionally substituted by one to three radicals independently of one another selected from the group of hydroxy, cyano, halogen, trifluoromethyl, trifluoromethoxy, hydroxycarbonyl and a group of the formula —NR 3 R 4 , where R 3 and R 4 have the meanings indicated above, or a salt, solvate or solvate of a salt thereof.