Patent ID: 7125552

Claim:
A method for producing a high yield of purified immune globulins, comprising: suspending immune globulins in an ethanol solution; adjusting the pH of the suspension to about 5.7 to 5.8; incubating the suspension for at least two hours; adding a solution of glycine, ethanol and water to the suspension; adjusting the pH of the suspension to about 5.2 to 5.4; extracting the immune globulins from the suspension in a liquid phase to provide an extract containing immune globulins; concentrating the extract containing immune globulins, and removing any impurities from the extract containing immune globulins using an anion exchange chromatography column to provide a purified extract solution containing immune globulins; concentrating the purified extract solution containing immune globulins to provide a concentrated purified extract solution containing immune globulins; treating the concentrated purified extract solution containing immune globulins with a solvent-detergent mixture to inactivate viruses, and removing the solvent-detergent mixture from the concentrated purified extract solution containing immune globulins; and formulating the concentrated purified extract solution containing immune globulins for final use.