Patent ID: 7015246

Claim:
Compounds of the general formula (I) in which Z is O, S, SO, SO 2 , CHF or CF 2 , R 1 and R 2 are identical or different and are hydrogen, halogen, cyano, (C 1 –C 6 )-alkyl, CF 3 , CHF 2 , CH 2 F, vinyl or (C 3 –C 7 )-cycloalkyl, R 3 is hydrogen, halogen, cyano, (C 1 –C 6 )-alkyl or CF 3 , R 4 is hydrogen, hydroxyl, halogen, cyano, nitro, (C 1 –C 4 )-alkyl or the radical of the formula NR 9 R 10 , where R 9 and R 10 are identical or different and are in each case hydrogen, phenyl, benzyl, (C 1 –C 6 )-alkyl or (C 3 –C 8 )-cycloalkyl, which, for their part, are optionally substituted, once or more than once, identically or differently, by halogen, hydroxyl, amino, carboxyl, (C 1 –C 4 )-alkoxy, (C 1 –C 4 )-alkoxycarbonyl, (C 1 –C 4 )-alkoxycarbonylamino, (C 1 –C 5 )-alkanoyloxy, or phenyl which is optionally substituted by halogen or hydroxyl, R 5 forms, together with the two carbon atoms of the phenyl ring, a saturated or unsaturated furan ring which is optionally substituted, once or twice, identically or differently, R 6 is hydrogen, cyano, halogen or a group of the formula -M a -R 11 in which; M is a carbonyl group, a sulfonyl group or a methylene group, a is the number 0 or 1 or, in the case where M is a methylene group, is a number 0, 1, 2 or 3, and R 11 is hydrogen, OR 15 , NR 16 R 17 , (C 1 –C 10 )-alkyl, (C 3 –C 8 )-cycloalkyl, (C 2 –C 6 )-alkenyl, (C 6 –C 10 )-aryl, or (C 6 –C 10 )-arylmethyl, where the abovementioned radicals are optionally substituted by one, two or three identical or different substituents selected from the group halogen, hydroxyl, oxo, cyano, nitro, amino, NR 18 R 19 , trifluoromethyl, (C 1 –C 6 )-alkyl, (C 1 –C 6 )-alkoxy which is optionally substituted by R 20 , (C 3 –C 8 )-cycloalkyl, (C 6 –C 10 )-aryl which is, for its part, optionally substituted by halogen, (C 1 –C 4 )-alkyl, (C 1 –C 4 )-alkoxy, trifluoromethyl, nitro or cyano, —O—C(O)—R 21 , —C(O)—OR 22 , —C(O)—NR 23 R 24 , —SO 2 —NR 25 R 26 , —NH—C(O)—R 27 and —NH—C(O)—OR 28 , where R 15 to R 28 have the meanings given for R 9 or R 10 and, independently of each other, are identical to or different from this substituent, R 7 is hydrogen cation alkyl or acctyl, and also their pharmaceutically tolerated salts, solvates, hydrates and hydrates of the salts.