Patent ID: 7883724

Claim:
A method of collecting and quantifying a sample of saliva from the oral cavity in order to detect a test substance, comprising the steps of (a) cleaning the oral cavity, (b) stimulating saliva secretion with a saliva-collecting solution, said saliva collecting solution comprising an aqueous solution comprising a substance with taste-stimulating properties, which stimulates saliva secretion, in a range of 0.0005% by weight per volume lower limit up to 10% by weight per volume upper limit; an indicator substance, tartrazine in concentration in a range of 0.0001% by weight per volume lower limit up to 5% by weight per volume upper limit to indicate the ratio of saliva saliva-collection solution; and said saliva-collection solution having an optical density at a wavelength of 450 nm within a range of 1.5 up to 2.6; (c) removing the saliva-saliva collecting solution mixture from the oral cavity and collecting it in a container ( 1 ) in FIG. 1 , and (d) transferring the saliva-saliva collecting solution mixture to a sealable, optionally evacuated, collection vessel, (e) measuring optical density of the collected solution and comparing with the measurement of control solution, wherein the difference in measurement indicates the presence of the test substance.