Patent ID: 7858079

Claim:
A biocompatible composition comprising: a biocompatible biotin-containing component comprising a first polymer selected from the group consisting of polyethylene glycols and absorbable polymers, wherein the first polymer is functionalized with biotin; and a biocompatible avidin-containing component comprising a second polymer selected from the group consisting of polyethylene glycols and absorbable polymers, wherein the second polymer is functionalized with avidin or streptavidin, wherein the composition is suitable for in vivo contact with tissue, wherein at least the first polymer or the second polymer is an absorbable polymer selected from the group consisting of polycaprolactone, poly-D,L-lactic acid, poly-L-lactic acid, poly(lactide-co-glycolide), poly(hydroxybutyrate), poly(hydroxybutyrate-co-valerate), polydioxanone, polyorthoester, polyanhydride, poly(glycolic acid), poly(glycolic acid-cotrimethylene carbonate), polyphosphoester, polyphosphoester urethane, polyglutamic acid, polyaspartic acid, absorbable cyanoacrylates, poly(trimethylene carbonate), copoly(ether-esters), polyalkylene oxalates, polyphosphazenes, polyiminocarbonates, aliphatic polycarbonates, and combinations thereof, and wherein the biotin-containing component and the avidin-containing component form a gel matrix when the two components are combined.