Patent ID: 7342038

Claim:
A compound having the structural formula (I): or a pharmaceutically acceptable salt or hydrate thereof wherein: the bond - - - designates a single or double bond; m is 0, 1, 2 , 3 or 4; each n is independently 0, 1, 2, 3, 4 or 5; X is N; Y is absent, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl or (C 2 -C 6 ) alkynyl; R 1 is absent, —OR, —SR, —O—C(O)R, —S—C(O)R, —O—C(S)R, or —S—C(S)R; R 2 is absent; R 3 is absent or —H; wherein, when R 1 is absent, then R 3 is also absent and the bond - - - is a double bond, R 4 is —O(C 2 -C 6 ) alkyl, —O(C 2 -C 6 ) alkenyl, —O(C 2 -C 6 ) alkynyl, —S(C 1 -C 6 ) alkyl, —S(C 2 -C 6 ) alkenyl, —S(C 2 -C 6 ) alkynyl, —N(R′) 2 , —CN, —NO 2 , (C 3 -C 8 ) cycloalkyl, 3-8 membered heterocycloalkyl, —C(O)R′, —C(S)R′, —C(O)OR′, —C(S)OR′, —C(O)SR′, —C(S)SR′, —C(O)N(R′) 2 or —C(S)N(R′) 2 ; each R 5 , R 6 and R 7 is independently selected from the group -halogen, —R′, —OR′, —SR′, —N(R′) 2 , —ON(R′) 2 , —SN(R′) 2 , —NO 2 , —CN, —C(O)R′, —C(S)R′, —C(O)OR′, —C(O)SR′, —C(S)OR′, —CS(S)R′, —C(O)N(R′) 2 , —C(S)N(R′) 2 , —C(O)NR′(OR′), —C(S)NR′(OR′), —C(O)NR′(SR′), —C(S)NR′(SR′), —CH(CN) 2 , —CH[C(O)R′] 2 , —CH[C(S)R′] 2 , —CH[C(O)OR′] 2 , —CH[C(S)OR′] 2 , —CH[C(O)SR′] 2 and —CH[C(S)SR′] 2 ; each R is independently selected from the group —H, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, (C 5 -C 20 ) aryl, substituted (C 5 -C 20 ) aryl, (C 6 -C 26 ) alkaryl and substituted (C 6 -C 26 ) alkaryl; the heterocycloalkyl substituents are each independently selected from the group —CN, —NO 2 , —N(R′) 2 , —OR′, —C(O)N(R′) 2 , —C(S)N(R′) 2 , —C(O)OR′, —C(S)OR′, —C(O)SR′, —C(S)SR′ and trihalomethyl; the aryl and alkaryl substituents are each independently selected from the group -halogen, —C(O)R′, —C(S)R′, —C(O)OR′, —C(S)OR′, —C(O)SR′, —C(S)SR′, —C(O)N(R′) 2 , —C(S)N(R′) 2 and trihalomethyl; and each R′ is independently selected from the group —H, (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl and (C 2 -C 6 ) alkynyl; with the proviso that when - - - is a double bond, and R 1 , R 3 and Y are absent, then R 4 is other than NH 2 .