Patent ID: 7189416

Claim:
A method for stabilizing the salts of (−)-hydroxycitric acid with fumed silicon dioxide as the desiccating agent whereby said agent is admixed with hydrated (−)-hydroxycitrate to make a granulate which is then treated as a material for further pharmaceutical formulation by encasing the resulting powders consisting of the salts of (−)-hydroxycitric acid in acid resistant hydrophobic polymers to produce (−)-hydroxycitrate granulate resistant to environmental moisture, resistant to lactonization under acid environments and resistant to undesirable binding, said method comprising the steps of: (1) obtaining a salt of (−)-hydroxycitric acid or a combination of salts of (−)-hydroxycitric acid, (2) blending said salt or combination of said salts of (−)-hydroxycitric acid with a suitable fumed silicon dioxide, and (3) blending the resulting material with said acid resistant hydrophobic polymer wherein the polymer is selected from the group consisting of cellulose acetate phthalate, ethyl cellulose, zein, acrylic polymers, hydroxymethylpropylmethyl cellulose phthalate, polyvinyl acetate phthalate, cellulose acetate trimalleate, acrylic polymer plasticizers, polymers of poly lactic acid, polymers of glycolic acid, and mixtures thereof, wherein the encased powder product of steps (1), (2) and (3) is formulated into tablets, capsules, prepared dry drink mixes, prepared acidic liquid drinkable products and acidic edible bars.