Patent ID: 7163940

Claim:
A compound of formula (I): wherein: R 1 is selected from the group consisting of halo, —NR 7 R 8 , Ay, —NR 7 Ay, Het, —NH(CH 2 ) m Het, and —NH(CH 2 ) l Ay; each R 7 and R 8 are the same or different and are independently selected from the group consisting of H, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkylhydroxy, amine, alkylamine, alkylcarboky, alkylcarboxamide, alkyl alkoxycarbonyl, alkylthioamide, alkylsulfonyl, alkylsulfonamide, alkylether, —(CH 2 ) l -cycloalkyl, —(CH 2 ) l NHCOR 9 and —(CH 2 ) m SO 2 NHCOR 9 ; l is 1–6; m is 0–6; R 9 is H, alkyl, cycloalkyl, alkylhydroxy, amine, alkylamine, alkylcarboxy and alkylether; Ay is aryl; Het is a 5- or 6-membered heterocyclic or heteroaryl group; R 2 is selected from the group consisting of H, halo, alkyl, cycloalkyl, alkenyl, cycloalkenyl, —NR 7 R 5 , —OR 7 , —OAy, —S(O) n R 7 , —S(O) n Ay, —R 10 NR 7 R 8 , —R 10 NR 7 Ay, Ay, Het, —NH(CH 2 ) m Het and —O(CH 2 ) m Het; n is 0, or 2; R 10 is alkyl or alkenyl; Y is N; R 3 and R 4 are each independently selected from the group consisting of H, halo, hydroxy, alkyl, alkylhydroxy, alkylamine, alkylether, —OR 7 , —OAy, —NR 7 R 8 , —NR 7 Ay, carboxy, carboxamide, —SO 2 NHR 9 , Het and Ay; and R 5 is halo; or a pharmaceutically acceptable salt thereof.