Patent ID: 8187628

Claim:
A dermal composition comprising a blend of a firstacrylic-based adhesive polymer and a second acrylic-based adhesive polymer prepared by: (A) mixing in a volatile organic solvent: (I) a polymer composition comprising two or more polymers including: (a) a first acrylic-based adhesive polymer having substantially no functional groups and a first solubility parameter, wherein the first acrylic-based adhesive polymer is produced from monomers of alkyl acrylic or methacrylic esters; and (b) a second acrylic-based adhesive polymer having functional groups and a second solubility parameter, wherein: (i) the functional groups are selected from the group consisting of carboxyl groups, hydroxy groups, and epoxy groups; and (ii) the monomers containing functional groups are present in the second acrylic-based adhesive polymer in a range from 0.1 to 8% by weight, based on the dry weight of the second acrylic-based adhesive polymer; to provide an organic solution of an acrylic-based adhesive polymer blend composition having a net functionality proportional to the weight ratio of the first and second acrylic-based adhesive polymers, wherein the first and second acrylic-based adhesive polymers are present in proportions to provide a net solubility parameter for one or more drugs; and (II) a therapeutically effective amount of the one or more drugs; (III) optionally, one or more enhancers; (IV) optionally, one or more additive or excipients; (V) optionally, one or more non-volatile pharmaceutically acceptable solvents; and (B) removing the volatile organic solvent to produce the dermal composition.