Patent ID: 7705018

Claim:
A compound having the structure: or any pharmaceutically-acceptable salt thereof, wherein: Y is N(R 11 ), O or S; R 1 is phenyl substituted by R 2 , and the phenyl is additionally substituted by 0, 1, 2 or 3 substituents independently selected from halo, nitro, cyano, C 1-4 alkyl, OC 1-4 alkyl, OC 1-4 haloalkyl, NHC 1-4 alkyl, N(C 1-4 alkyl)C 1-4 alkyl and C 1-4 haloalkyl; R 2 is selected from halo, C 1-4 haloalkyl, cyano, nitro, —C(═O)R a , —C(═O)OR a , —C(═O)NR a R a , —C(═NR a )NR a R a , —OR a , —OC(═O)R a , —OC(═O)NR a R a , —OC(═O)N(R a )S(═O) 2 R a , —OC 2-6 alkylNR a R a , —OC 2-6 alkylOR a ,—SR a , —S(═O)R a , —S(═O) 2 R a , —S(═O) 2 NR a R a , —S(═O) 2 N(R a )C(═O)R a , —S(═O) 2 N(R a )C(═O)OR a , —S(═O) 2 N(R a )C(═O)NR a R a , —NR a R a , —N(R a )C(═O)R a , —N(R a )C(═O)OR a —N(R a )C(═O)NR a R a , —N(R a )C(═NR a )NR a R a , —N(R a )S(═O) 2 R a , —N(R a )S(═O) 2 NR a R a —NR a C 2-6 alkylNR a R a and —NR a C 2-6 alkylOR a ; R 3 is selected from F, Cl, C 1-6 alkyl, phenyl, benzyl, heteroaryl and heterocycle, wherein the C 1-6 alkyl, phenyl, benzyl, heteroaryl and heterocycle are additionally substituted by 0, 1, 2 or 3 substituents selected from C 1-6 haloalkyl, OC 1-6 alkyl, Br, Cl, F, I and C 1-6 alkyl; R 5 methyl; R 6 is H; R 7 is selected from C 1-6 haloalkyl, Br, Cl, F, I, OR a , NR a R a , C 1-6 alkyl, phenyl, benzyl, heteroaryl and heterocycle, wherein the C 1-6 alkyl, phenyl, benzyl, heteroaryl and heterocycle are additionally substituted by 0, 1, 2 or 3 substituents selected from C 1-6 haloalkyl, OC 1-6 alkyl, Br, Cl, F, I and C 1-6 alkyl; R 8 is selected from H, halo, C 1-4 haloalkyl, cyano, nitro, —C(═O)R a , —C(═O)OR a , —C(═O)NR a R a , —C(═NR a )NR a R a , —S(═O)R a , —S(═O) 2 NR a R a , —S(═O) 2 N(R a )C(═O)R a ,—S(═O) 2 N(R a )C(═O)OR a and —S (═O) 2 N(R a )C(═O)NR a R a ; R 9 is H; R 11 is H or C 1-4 alkyl; R a is independently, at each instance, H or R b ; and R b is independently, at each instance, phenyl, benzyl or C 1-6 alkyl, the phenyl, benzyl and C 1-6 alkyl being substituted by 0, 1, 2 or 3 substituents selected from halo, C 1-4 alkyl, C 1-3 haloalkyl, —OC 1-4 alkyl, —NH 2 , —NHC 1-4 alkyl, —N(C 1-4 alkyl)C 1-4 alkyl.