Patent ID: 8791142

Claim:
A compound of formula (I): wherein: R 1 denotes —CO 2 R 3 , —CON(H) 2-p (A) p , —N(H)(CH 2 ) n CO 2 R 3 , —N(R 3 )(CH 2 ) n CO 2 R 3 , —NH—CO-A, Hal, —CF 3 , —OCF 3 , —OH, —OA, —CN, or —NO 2 , —(CH 2 ) s N(H) 2-p (A) p , —CH(CH 3 )(CH 2 ) n N(H) 2-p (A) p , —CH(R 3 )(CH 2 ) n N(H) 2-p (A) p , —(CH 2 ) s N(R 3 )(CH 2 ) n CO 2 R 3 , —(CH 2 ) s NH—CO-A, —(CH 2 ) n N(R 3 ) 2 , —CH(CH 3 )(CH 2 ) n N(R 3 )CH(CH 3 )(CH 2 ) n CO 2 R 3 , or —CH(R 3 )(CH 2 ) n N(R 3 )CH(R 3 )(CH 2 ) n CO 2 R 3 , or when in position meta or para to the oxadiazole ring, R 1 also denotes —N(H) 2-p (A) p or A, R 2 is H, Hal, —CN, —NO 2 , —OH, OA, —CO 2 R 3 , —CON(H) 2-p (A) p , —N(H)(CH 2 ) n CO 2 R 3 , —NH—CO-A, —CF 3 , or —OCF 3 , or when in position meta or para to the oxadiazole ring, R 2 also denotes —N(H) 2-p (A) p or A, R a and R b are independently from each other A, —CF 3 , Hal, —CH 2 —OR 3 , OR 3 , —OCF 3 , (C 1 -C 7 )alkyl, —(CH 2 ) n O(CH 2 ) n OMe or CH(CH 3 )OCH 3 , W, Y are independently from each other CH, Z denotes Ar, A is branched or linear alkyl having 1 to 12 C-atoms, wherein one or more H-atoms are optionally substituted Hal, OR 3 , CN, CO 2 R 3 or N(R 3 ) 2 and wherein one or more non-adjacent CH 2 -groups are optionally substituted by O, NR 3 or S and/or by —CH═CH— or —C≡C— groups, or A denotes a cycloalkyl or cycloalkylalkylene having 3-7 ring C atoms, Ar denotes a monocyclic or bicyclic, aromatic carbocyclic ring having 6 carbon atoms, which is unsubstituted, monosubstituted, disubstituted or trisubstituted by Hal, —CF 3 , —OCF 3 , —NO 2 , —CN, perfluoroalkyl, A, OA, —OH, —NH 2 , —COH, —COOR 3 , —CONH 2 , —CON(H) 2-q A q , —NR 3 (CH 2 ) n COA, —NR 3 (CH 2 ) n COOA, —NR 3 (CH 2 ) n COR 3 , —N(H) 2-q A q , —NHSO 2 A, —NHSO 2 —N(H) 2-m (A) m , —N(H) 1-q A q COA, —N(H) 1-q A q SO 2 —N(H) 2-m (A) m , —N(H) 1-q A q CON(H) 2-m (A) m , —COOA, —SO 2 A, —SO 2 N(H) 2-m (A) m , or —(CH 2 ) n OR 3 , Hal is F, Cl, Br or I, R 3 is H or A, m is 0, 1 or 2, p is 0, 1 or 2, q is 0 or 1, s is 1, 2, 3, 4 or 5, n is 0, 1, 2, 3, 4 or 5, and pharmaceutically acceptable salts thereof.