Patent ID: 7618620

Claim:
An aqueous composition suitable for topical ophthalmic administration comprising three polymeric ingredients having a synergistic effect on the composition's viscosity wherein the three polymeric ingredients are hydroxypropyl methylcellulose in a concentration range of 0.05-0.5% (w/v) and a combination of two polymers selected from the group of combinations consisting of guar gum and a carboxyvinyl polymer; guar gum and hydroxyethyl cellulose; guar gum and dextran; hydroxyethyl cellulose and a carboxyvinyl polymer; and dextran and a carboxyvinyl polymer, provided that if the composition comprises a carboxyvinyl polymer then the composition does not contain sodium chloride or boric acid, and further provided that the viscosity of the composition is greater than 150% of the sum of the viscosities of three single polymer compositions that contain only one of the three polymeric ingredients, respectively.