Patent ID: 7169805

Claim:
A compound of general formula (I) and/or a pharmaceutically acceptable salt or stereoisomer thereof wherein: Q=—CO—, —OCO—, —CONH—, —COCH(R)NH— wherein R is H, straight or branched (C 1 –C 6 )-alkyl, —(CH 2 ) 2 SCH 3 or benzyl; with the proviso that —S— is bound to —CO; n is an integer equal to 0 or 1; A=H, W (wherein W is C 1 –C 6 -alkyl, phenyl or benzyl) or is chosen from the following groups: wherein z and Y are the same or different, and are H or straight or branched (C 1 –C 4 )-alkyl; with the proviso that when A is selected from the groups 1b and 1c, Q=—CO—; wherein z and Y are as above defined; with the proviso that when A is selected from the groups 1d 1 –1d 3 , Q=—COCH(R)NH— wherein R is as above defined; R 3 is a bivalent radical having the following meanings: a) straight or whenever possible branched C 1 –C 20 alkylene, optionally substituted with at least an halogen atom or an optionally substituted cycloalkylene having from 5 to 7 carbon atoms; wherein: n3 is an integer from 0 to 20; n3′ is an integer from 1 to 20; wherein the —ONO 2 group is bound to a —CH 2 group; wherein X 1 is —O— or —S—, m is an integer from 1 to 6, m 1 is an integer from 1 to 10, Rf is a hydrogen atom or CH 3 , Rf is CH 3 ; or wherein: nIX is an integer from 0 to 10; nIIX is an integer from 1 to 10; R TIX , R TIX′ , R TIIX , R TIIX′ , are the same or different, and are H or straight or branched (C 1 –C 4 -alkyl; and wherein the —ONO 2 group is bound to Y 3 is a heterocyclic saturated, unsaturated or aromatic 5 or 6 members ring, containing one or more heteroatoms selected from nitrogen, oxygen, and sulphur, X=—O—, —S—; B=H, —R 3a —ONO 2 wherein R 3a has the same meaning of R 3 as above defined or is chosen from the following groups: wherein n3′ is as above defined; wherein the —ONO 2 group is bound to the group —(CH 2 ) n3′ ; wherein R 2 is H, a straight or branched (C 1 –C 6 )-alkyl or —R 3b —ONO 2 , R 3b has the same meaning of R 3 as above defined in a); provided that: i) when R 3a is the group as defined in f) and g) then A is W; ii) when R 3a is the group as defined in g) then X is —S—; iii) at least one of the groups A or B contains a —ONO 2 group.