Patent ID: 8483793

Claim:
A method for providing a substantially noise-free glucose signal for a glucose sensor implanted in a host, the method comprising: providing a sensor, the sensor comprising a first working electrode disposed beneath an active enzymatic portion of a membrane system, and a second working electrode disposed beneath an inactive-enzymatic or a non-enzymatic portion of the membrane system, wherein the membrane system is configured to substantially reduce one or more interfering species from reaching the first working electrode and the second working electrode; generating a first signal associated with the first working electrode; generating a second signal associated with the second working electrode; processing the first signal and the second signal to produce a glucose signal that is substantially without signal contribution from interfering species; and performing, using electronic circuitrty, a self-diagnosis by measuring an auxiliary signal to determine a change in sensitivity of the sensor using one or more electrodes of the sensor, independent of a blood glucose reference value.