Patent ID: 7851495

Claim:
A compound of formula I: wherein R 1 is H, C 1-6 aliphatic, or C 3-6 cycloaliphatic; G is —C(R) 2 — or —O—; L is C 0-3 aliphatic optionally substituted with 0-3 J L ; Ring A is triazolyl optionally substituted with 0-3 J A ; Ring B is 5-6 membered aromatic monocyclic ring containing 0-3 heteroatoms selected from O, N, and S; Ring B is optionally substituted with 0-5 J B and optionally fused to Ring B′; Ring B′ is a 5-8 membered aromatic or nonaromatic monocyclic ring containing 0-3 heteroatoms selected from O, N, and S; Ring B′ is optionally substituted with 0-4 J B′ ; each J A , J B , and J B′ is independently C 1-6 haloalkyl, halo, NO 2 , CN, Q, or —Z-Q; Z is independently C 1-6 aliphatic optionally interrupted with 0-3 occurrences of —NR—, —O—, —S—, —C(O)—, —C(═NR)—, —C(═NOR)—, —SO—, or —SO 2 —; each Z is optionally substituted with 0-2 J Z ; Q is H; C 1-6 aliphatic; a 3-8-membered aromatic or nonaromatic monocyclic ring having 0-3 heteroatoms independently selected from O, N, and S; or an 8-12 membered aromatic or nonaromatic bicyclic ring system having 0-5 heteroatoms independently selected from O, N, and S; each Q is optionally substituted with 0-5 J Q ; each J L and J Z is independently H, halo, C 1-6 aliphatic, C 3-6 cycloaliphatic, NO 2 , CN, —NH 2 , —NH(C 1-4 aliphatic), —N(C 1-4 aliphatic) 2 , —OH, —O(C 1-4 aliphatic), —CO 2 H, —CO 2 (C 1-4 aliphatic), —O(haloC 1-4 aliphatic), or halo(C 1-4 aliphatic); each J Q is independently M or —Y-M; each Y is independently an unsubstituted C 1-6 aliphatic optionally interrupted with 0-3 occurrences of —NR—, —O—, —S—, —C(O)—, —SO—, or —SO 2 —; each M is independently H, C 1-6 aliphatic, C 3-6 cycloaliphatic, halo(C 1-4 aliphatic), —O(haloC 1-4 aliphatic), C 3-6 heterocyclyl, halo, NO 2 , CN, OH, OR′, SH, SR′, NH 2 , NHR′, N(R′) 2 , COH, COR′, CONH 2 , CONHR′, CONR′ 2 , NHCOR′, NR′COR′, NHCONH 2 , NHCONHR′, NHCON(R′) 2 , SO 2 NH 2 , SO 2 NHR′, SO 2 N(R′) 2 , NHSO 2 R′, or NR′SO 2 R′; R is H or unsubstituted C 1-6 aliphatic; R′ is unsubstituted C 1-6 aliphatic; or two R′ groups, together with the atom to which they are bound, form an unsubstituted 3-8 membered nonaromatic monocyclic ring having 0-1 heteroatoms independently selected from O, N, and S.