Patent ID: 7271270

Claim:
A compound of the formula: or a pharmaceutically acceptable salt, prodrug or hydrate thereof, wherein: n is an integer from 0 to 3; R 2 is chosen from optionally substituted C 1 –C 8 alkyl, optionally substituted C 3 –C 8 cycloalkyl, optionally substituted C 3 –C 8 cycloalkyl(C 1 –C 8 )alkyl optionally substituted C 2 –C 8 alkenyl, optionally substituted C 2 –C 8 alkynyl, haloalkyl, and aminoalkyl, each of which is unsubstituted or substituted with one or more substituents selected from oxo, hydroxy, alkoxy, amide, ester, cyano, acetoxy and nitro; R 4 is hydrogen or alkyl, alkenyl, alkynyl, cycloalkyl, (cycloalkyl)alkyl or haloalkyl, each of which is substituted or unsubstituted; or R 4 is optionally substituted carbocyclic aryl, optionally substituted arylalkyl, or an optionally substituted heteroaromatic or heteroalicyclic group having from 1 to 3 rings, 3 to 8 members in each ring and from 1 to 3 heteroatoms; R 3 and R 3A are the same or different and represent hydrogen or alkyl; or R 3 and R 3A , taken together with the carbon atom to which they are attached, form a cycloalkyl ring; R 5 and R 6 are the same or different and represent hydrogen, halogen, hydroxy, alkyl, or alkoxy; or R 5 and R 6 , taken together with the carbon atom to which they are attached form a cycloalkyl ring; R 5a and R 6a are independently selected at each occurrence from hydrogen, halogen, hydroxy, alkyl, and alkoxy; R 7 represents hydrogen or alkyl; Ar 1 is optionally substituted carbocyclic aryl, optionally substituted arylalkyl, or an optionally substituted heteroaryl or heteroalicyclic group having from 1 to 3 rings, 3 to 8 members in each ring and from 1 to 3 heteroatoms; and Ar 2 is optionally substituted carbocyclic aryl, optionally substituted arylalkyl, or an optionally substituted heteroaryl or heteroalicyclic group having from 1 to 3 rings, 3 to 8 members in each ring and from 1 to 3 heteroatoms.