Patent ID: 8273770

Claim:
A compound of formula I: wherein n is 0 or 1; R is an optionally substituted pyrrolidin-1-yl; R 3 and R 4 are each independently H or alkyl; B is selected from aryl, and cycloalkyl; R 5 , R 6 , R 7 are each independently selected from H, —OH, —O-alkyl, alkyl, halo, —CF 3 , —CN, and —O-aryl; and R 14 is H or —OH; wherein optional substituents are selected from the group consisting of alkyl, halogen, haloalkyl, hydroxy, lower alkoxy, carboxy, carboalkoxy, carboxamido, cyano, carbonyl, nitro, amino, alkylamino, dialkylamino, mercapto, alkylthio, sulfoxide, sulfone, acylamino, amidino, phenyl, benzyl, heteroaryl, phenoxy, benzyloxy, and heteroaryloxy; and provided that when n is 0, R 3 and R 4 are H and R is pyrrolidin-1-yl, then when B is phenyl which is substituted at the 2-position by methoxy or at the 3-position by methyl, there is at least one additional substituent on the phenyl ring; or pharmaceutically acceptable salt thereof.