Patent ID: 7495068

Claim:
A compound having the formula A-B-C-X-Y or a pharmaceutically acceptable salt, ester or ester prodrug thereof, wherein A is absent or a nitrogen protecting group; Y is absent or a carboxylic acid protecting group; B is absent or is from 1 to 97 naturally-occurring amino acid residues corresponding to the sequence from amino acid position 334 to amino acid position 530 of SEQ ID NO: 1; C is R 1 —R 2 —R 3 —R 4 wherein R 1 is lysyl; R 2 is leucyl or arginyl; R 3 is tyrosyl, 3-I-tyrosyl or phenylalanyl; R 4 is aspartyl; and X is absent or is from 1 to 12 naturally-occurring amino acid residues corresponding to the sequence from amino acid position 535 to about amino acid position 546 of SEQ ID NO: 1.