Patent ID: 6878739

Claim:
A method for treating glomerulopathy which comprises administering an effective amount of a compound of the formula (I) and a pharmaceutically acceptable carrier: wherein R 1 is optionally substituted lower alkyl or optionally substituted heteroarylalkyl; R 2 is hydrogen, optionally substituted lower alkyl, optionally substituted aryl, or optionally substituted aralkyl; R 3 is 1,4-phenylene; R 4 is a substituent represented by the formula: wherein R 5 is hydrogen atom, hydroxy, optionally substituted lower alkyloxy, mercapto, lower alkylthio, cycloalkyl, halogen, carboxy, lower alkyloxycarbonyl, nitro, cyano, lower holoalkyl, aryloxy, optionally substituted amino, guanidino, optionally substituted lower alkyl, lower alkenyl, lower alkynyl, acyl, acyloxy, —CONR A R B , —N(R C )COR D (wherein R A , R B , and R C are the same or different selected from hydrogen atom, lower alkyl, and aralkyl; R D is lower alkyl, aryl, or aralkyl), optionally substituted non-aromatic heterocyclic group, or optionally substituted heteroaryl; and Y is OH, its optically active substance, their pharmaceutically acceptable salt, or hydrate thereof.