Patent ID: 7022696

Claim:
A compound of formula I in which R1 and R2 are both hydrogen or together form an additional bond, R3 represents a benzene derivative of formula (a) or (b) wherein R4 is 1–4C-alkoxy or 1–4C-alkoxy which is completely or predominantly substituted by fluorine, R5 is 1–8C-alkoxy, 3–7C-cycloalkoxy, 3–7C-cycloalkylmethoxy, or 1–4C-alkoxy which is completely or predominantly substituted by fluorine, R6 is 1–4C-alkoxy, 3–5C-cycloalkoxy, 3–5C-cycloalkylmethoxy, or 1–4C-alkoxy which is completely or predominantly substituted by fluorine, R7 is 1–4C-alkyl and R8 is hydrogen or 1–4C-alkyl, or wherein R7 and R8 together and with inclusion of the two carbon atoms, to which they are bonded, form a spiro-linked 5-, 6- or 7-membered hydrocarbon ring, optionally interrupted by an oxygen or sulphur atom, A is a bond or methylene (—CH 2 —), R9 is —C(O)R10, —(CH 2 ) m —C(O)R11, —(CH 2 ) n R12, Aryl, Hetaryl, phenylprop-1-en-3-yl or 1-methyl-piperidin-4-yl, R10 hydrogen, 1–4C-alkyl, —OR13, furanyl, indolyl, phenyl, pyridyl, phenyl substituted by R16 and/or R17 or pyridyl substituted by R18 and/or R19, R11 is —N(R14)R15, R12 is —N(R14)R15, tetrahydrofuranyl or pyridinyl, R13 is 1–4C-alkyl, R14 is hydrogen, 1–4C-alkyl, 3–7C-cycloalkyl or 3–7C-cycloalkylmethyl, R15 is hydrogen, 1–4C-alkyl, 3–7C-cycloalkyl or 3–7C-cycloalkylmethyl, or R14 and R15 together and with inclusion of the nitrogen atom to which they are bonded, form a 4-morpholinyl-, 1-pyrrolidinyl-, 1-piperidinyl- or 1-hexahydroazepinyl-ring, Aryl is phenyl, pyridyl, pyrimidinyl, phenyl substituted by R16 and/or R17, pyridyl substituted by R18 and/or R19, R16 is halogen, nitro, 1–4C-alkyl, trifluoromethyl or 1–4C-alkoxy, R17 is halogen or 1–4C-alkyl, R18 is halogen, nitro, 1–4C-alkyl, trifluoromethyl or 1–4C-alkoxy, R19 is halogen or 1–4C-alkyl, Hetaryl is indol-4-yl, 2-methyl-quinolin-4-yl, 5-chloro-6-oxo-1-phenyl-1,6-dihydro-pyridazin-4-yl, 3-phenyl-1,2,4-thiadiazol-5-yl or 3-o-tolyl-1,2,4-thiadiazol-5-yl, n is an integer from 1 to 4, m is an integer from 1 to 4, s is an integer from 1 to 2, X is —C(O)— or —S(O) 2 —, or a hydrate, salt, or hydrate of a salt thereof.