Patent ID: 8846748

Claim:
A compound of formula (I): wherein is a single bond or a double bond; n is 0, 1, or 2; R 1 is SO 2 R a , in which R a is alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; R 2 is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, halo, cyano, nitro, OR b , SR b , S(O)R b , NHC(O)—CH═CH—C(O)R b , NHC(O)—CH═CH—C(O)NR c R d , SO 2 NR c R d , OC(O)R b , C(O)NR c R d , NR c R d , NHC(O)R b , NHC(O)NR c R d , or NHC(S)R c , in which each of R b , R c , and R d , independently, is H, hydroxy, alkoxy, aryloxy, heteroaryloxy, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; each of R 3 , R 4 , R 5 , and R 6 , independently is, H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, halo, cyano, nitro, OR b , SR b , S(O)R b , CH═CH—C(O)NR c R d , NHC(O)—CH═CH—C(O)R b , NHC(O)—CH═CH—C(O)NR c R d , SO 2 NR c R d , OC(O)R b , C(O)NR c R d , NR c R d , NHC(O)R b , NHC(O)NR c R d , or NHC(S)R c , in which each of R b , R c , and R d , independently, is H, hydroxy, alkoxy, aryloxy, heteroaryloxy, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, or heterocycloalkenyl; and when R 1 is SO 2 R a , R 2 is NHC(O)—CH═CH—C(O)R b or NHC(O)—CH═CH—C(O)NR c R d ; at least one of R 3 , R 5 , and R 6 is CH═CH—C(O)NR c R d , NHC(O)—CH═CH—C(O)R b , or NHC(O)—CH═CH—C(O)NR c R d ; or R 4 is C(O)NR c R d , CH═CH—C(O)NR c R d , NHC(O)—CH═CH—C(O)R b , or NHC(O)—CH═CH—C(O)NR c R d .