Patent ID: 6946460

Claim:
A compound of the formula (I): wherein X is nitrogen or CH; Ar 1 is a carbocyclic or heterocyclic aryl, non-substituted or substituted by one or more R 2 , R 3 or R 4 ; Ar 2 is phenylene or naphthalene, non-substituted or substituted by one or more R 5 , R 6 or R 7 ; Ar 3 is a carbocyclic or heterocyclic aryl, non-substituted or substituted by one or more R 8 , R 9 or R 10 ; A is (C 1 -C 4 )-alkylene or C(O); B is (C 1 -C 4 )-alkylene-CH═CH— or (C 1 -C 4 )-alkylene-cyclopropylene, said cyclopropylene or —CH═CH— is optionally substituted by R 2 or R 3 ; R 1 is hydrogen, —SO 3 H or (C 1 -C 6 )alkyl, non-substituted or substituted by R 2 ; and wherein R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 or R 10 , are the same or different and are independently selected from the group consisting of; fluorine, chlorine, bromine, cyano, mono- bi- or trihalogeno(C 1 -C 8 )alkyl, mono- bi- or trihalogeno(C 1 -C 8 )-alkyloxy, hydroxy, nitro, carboxyl, formyl, —SO 3 H, —OSO 3 H, (R 11 O) 2 P(O)—, (R 11 O) 2 P(O)—O—, amino, (C 1 -C 8 )-alkylamino, di((C 1 -C 8 )alkyl)amino, (C 5 -C 14 )-aryl-(C 1 -C 6 )-alkylenamino or (C 5 -C 14 )-arylamino, (C 1 -C 8 )-alkyl, (C 5 -C 14 )aryl, a heterocycle optionally substituted by oxo, (C 5 -C 14 )aryl-(C 1 -C 6 )alkyl, amino-(C 1 -C 6 )-alkyl, (C 1 -C 8 )-alkylamino-(C 1 -C 6 )-alkyl, di-((C 1 -C 8 )alkyl)amino-(C 1 -C 6 )-alkyl, hydroxy-(C 1 -C 6 )alkyl, (C 1 -C 6 )-alkyloxy-(C 1 -C 6 )-alkyl, (C 1 -C 8 )-alkyloxy optionally interrupted by one or more oxygen atoms, (C 5 -C 14 )-aryl-(C 1 -C 6 )-alkylenoxy, (C 5 -C 14 )-aryloxy, hydroxy-(C 1 -C 6 )alkylenoxy, (C 1 -C 6 )-alkyloxy-(C 1 -C 6 )alkylenoxy, amino-(C 1 -C 6 )-alkylenoxy, (C 1 -C 6 )-alkylamino-(C 1 -C 6 )-alkylenoxy, di((C 1 -C 8 )-alkyl)amino-(C 1 -C 6 )-alkylenoxy, methylenedioxy, (C—C 6 )-alkyloxycarbonyl, (C 1 -C 6 )-alkylcarbonyl, (C 5 -C 14 )aryl-(C 1 -C 6 )-alkylenecarbonyl, (C 5 -C 14 )-arylcarbonyl, (C 1 -C 6 )-alkylaminocarbonyl, (C 1 -C 6 )alkanoylamino, (C 1 -C 6 )-alkylsulfonylamino, (C 5 -C 14 )-arylsulfonylamino, (C 5 -C 14 )-aryl-(C 1 -C 6 )-alkylenesulfonylamino, (C 1 -C 6 )-alkylaminosulfonyl, (C 5 -C 14 )-aryl-(C 1 - 1 )-alkylenaminosulfonyl, (C 1 -C 6 )-alkylsulfonyl, (C 5 -C 14 )-aryl-(C 1 -C 8 )-alkylenesulfonyl or (C 5 -C 14 )-aryl-sulfonyl, said alkyl, aryl or heterocycle are optionally substituted; and wherein R 11 is hydrogen, (C 1 -C 10 )-alkyl, (C 6 -C 14 )-aryl or (C 6 -C 14 )-aryl-(C 1 -C 6 )-alkyl, or an enantiomer, a stereoisomer, a tautomer or a mixture thereof, or a physiologically acceptable salt, a solvate or a derivative thereof, or a prodrug thereof.