Patent ID: 8399406

Claim:
A reconstituted surfactant composition, comprising: (a) 1.2 to 1.8% by weight of a polypeptide analog of the native surfactant protein SP-C having the sequence represented by the formula: (SEQ. ID NO: 1) IPSSPVHLKRLKLLLLLLLLILLLILGALLLGL; or a pharmaceutically acceptable salt thereof; (b) 0.1 to 0.5% by weight of a polypeptide analog of the native surfactant protein SP-B having the sequence represented by the formula: (SEQ. ID NO: 2) CWLCRALIKRIQALIPKGGRLLPQLVCRLVLRCS; and or a pharmaceutically acceptable salt thereof; and (c) a monounsaturated and a saturated phospholipid in a weight ratio of 45:55 to 55:45; all the amounts being calculated relative to the total weight of (a), (b), and (c), wherein the C residues at positions 1 and 33 of SEQ. ID NO:2 may be linked by a disulfide bond and the C residues at positions 4 and 27 of SEQ. ID NO:2 may be linked by a disulfide bond.