Patent ID: 8106191

Claim:
A compound of the formula: in which B 1 and B 2 are the same or different and are each independently H or a substituted or unsubstituted aliphatic, heteroaliphatic, aryl or heteroaryl moiety, selected such that G is one of the following: (a) —CH(B 2 )(YR 2 ) wherein B 2 is a branched, unbranched or cyclic, saturated or unsaturated, aliphatic moiety which may optionally contain a heteroatom in place of one or more —CH 2 — or CH units; and YR 2 is a substituted aryl or heteroaryl moiety; (b) —CH(B 1 )(YR 2 ) wherein Y is NH, —NH(C═O)—, —NH(SO 2 )— or NR 3 ; where B 1 is H or a substituted or unsubstituted aliphatic, heteroaliphatic, aryl or heteroaryl moiety; and (c) —C(B 1 )(B 2 )(OR 2 ) X is O; R 2 and R 3 are each independently a substituted or unsubstituted aliphatic, heteroaliphatic, aryl or heteroaryl moiety; R 4 is a substituted or unsubstituted, heterocyclic, aryl or heteroaryl group; R 5 is a substituted or unsubstituted, aliphatic moiety of 1 to 8 carbon atoms which may be branched, unbranched or cyclic; R 6 is a substituted or unsubstituted aliphatic, heteroaliphatic, heterocylic, aryl or heteroaryl moiety; and R 7 is H or —(CH 2 ) m CH═CH 2 , —(CH 2 ) m COOH, —(CH 2 ) m CHO, —(CH 2 ) m OH, —(CH 2 ) m SH, —(CH 2 ) m NH 2 or —(CH 2 ) m NH(alkyl), where m is 0, 1, 2, 3 or 4 and n is 2; wherein two or more of B 1 , B 2 and R 2 may be covalently linked to form a C 3 -C 7 cyclic moiety and wherein each aliphatic group comprises an alkyl group having 1-8 carbon atoms, an alkenyl group having 2-6 carbon atoms, an alkynyl group having 2-6 carbon atoms, or a cycloalkyl, cycloalkenyl, or cycloalkynyl group having 3-6 carbon atoms; and each heteroaliphatic group is an aliphatic group in which one or more carbon atoms are each replaced with an oxygen, nitrogen or sulfur atom.