Patent ID: 8828429

Claim:
A controlled release capsule preparation for oral administration, which comprises (i) an enteric granule comprising a plain granule wherein a core particle is coated with a coating layer comprising (1) a physiologically active substance which is (+)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide or a salt thereof, (2) a hydrophilic polymer which is hydroxypropylmethylcellulose, (3) an excipient which is microcrystalline cellulose, (4) a disintegrant which is croscarmellose sodium, (5) (a) an enteric coating agent which is methacrylic acid copolymers, (b) a lubricant which is talc, and (c) a plasticizer which is triethyl citrate, (ii) a fluidizer which is light anhydrous silicic acid, and (iii) a lubricant which is talc.