Patent ID: 7101856

Claim:
A compound of the formula I: wherein R1 is hydrogen, CF 3 , (C 1 -C 4 )-alkyl, or phenyl; R2 is hydrogen; A is═CH═CH—CH 2 — or (C 1 -C 4 )-alkanediyl, wherein one or two CH 2 groups are optionally replaced by —(C═O)—, —CH═CH—, —CH(OH)—, —NH—, —CHF—, —CF 2 —, or —O—; n is a number 2 or 3; Cyc1 is unsaturated ring, wherein 1 carbon atom is optionally replaced by O or S; R3, R4, R5 are, independently of each other, hydrogen, F, Cl, Br, I, OH, NO 2 , CN, COOH, COO(C 1 -C 6 )-alkyl, CO(C 1 -C 4 )-alkyl, CONH 2 , CONH(C 1 -C 6 )-alkyl, CON[(C 1 -C 6 )-alkyl] 2 , (C 1 -C 8 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 12 )-alkoxy, HO—(C 1 -C 6 )-alkyl, or (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, wherein one, more than one or all hydrogens in the alkyl and alkoxy radicals are optionally replaced by fluorine; SO 2 —NH 2 , SO 2 NH(C 1 -C 6 )-alkyl, SO 2 N[(C 1 -C 6 )-alkyl] 2 , S—(C 1 -C 6 )-alkyl, S—(CH 2 ) o -phenyl, SO—(C 1 -C 6 )-alkyl, SO—(CH 2 ) o -phenyl, SO 2 —(C 1 -C 6 )-alkyl, or SO 2 —(CH 2 ) o -phenyl, wherein o is 0-6 and wherein the phenyl radical is optionally substituted up to twice, each substituent chosen independently from F, Cl, Br, OH, CF 3 , NO 2 , CN, OCF 3 , (C 1 -C 6 )-alkoxy, (C 1 -C 6 )-alkyl, and NH 2 ; NH 2 , NH—(C 1 -C 6 )-alkyl, N((C 1 -C 6 )-alkyl) 2 , NH(C 1 -C 7 )-acyl, phenyl, (CH 2 ) o -phenyl, O—(CH 2 ) o -phenyl, wherein o is 0-6 and wherein the phenyl ring is optionally substituted one to 3 times, each substituent chosen independently from F, Cl, Br, I, OH, CF 3 , NO 2 , CN, OCF 3 , (C 1 -C 8 )-alkoxy, (C 1 -C 6 )-alkyl, NH 2 , NH(C 1 -C 6 )-alkyl, N((C 1 -C 6 )-alkyl) 2 , SO 2 —CH 3 , COOH, COO—(C 1 -C 6 )-alkyl, and CONH 2 ; or R3 and R4 together with the carbon atoms carrying them are a 5- to 7-membered, saturated, partially or completely unsaturated ring Cyc2, wherein 1 or 2 carbon atoms in the ring are optionally replaced by N, O or S, and wherein Cyc2 is optionally substituted by (C 1 -C 6 )-alkyl, (C 2 -C 5 )-alkenyl, (C 2 -C 5 )-alkynyl, wherein, in each substituent of Cyc2, one CH 2 group is optionally replaced by O, or substituted by H, F, Cl, OH, CF 3 , NO 2 , CN, COO(C 1 -C 4 )-alkyl, CONH 2 , CONH(C 1 -C 4 )-alkyl, or OCF 3 , and R5 is hydrogen; or a pharmaceutically acceptable salt thereof.