Patent ID: 8426438

Claim:
A compound of formula (I): wherein ring A is saturated or unsaturated, and is formed from 3 or 4 ring atoms, selected from the group consisting of S, O, CH, CH 2 , N and NH, wherein one or more of the ring atoms is optionally substituted by one or more R 1 , R 1 is optionally present at one or more of the ring A atoms, and each R 1 is selected from the group consisting of (1) halogen, (2) —C 1-6 alkyl, (3) —OC 1-6 alkyl, or (4) hydroxy, wherein the alkyl R 1 moiety is optionally substituted with one or more (a) halogen, (b) hydroxy, (c) —O—C 1-6 alkyl, or (d) —C 2-8 alkenyl, R 2 is optionally present at one or more of the ring carbon atoms, and each R 2 is selected from the group consisting of (1) halogen, (2) —C 1-6 alkyl, (3) —OC 1-6 alkyl, or (4) hydroxy, R 3 is selected from the group consisting of (1) —C 2-6 alkyl, (2) —C 6-10 aryl, or (3) heteroaryl, which is an aromatic cyclic group, having from five to twelve ring atoms, the ring atoms selected from C, O, N, N→O or S, at least one of which is O, N, N→O or S, wherein the alkyl, aryl or heteroaryl moiety is optionally substituted with one or more (a) halogen, (b) hydroxy, (c) —C 1-6 alkyl, (d) —O—C 1-6 alkyl, (e) —C 3-8 cycloalkyl, or (f) —C 6-10 aryl, or R 2 and R 3 together form a chain of 3 or 4 ring atoms, selected from the group consisting of S, CH, CH 2 , N and NH, wherein one or more of the ring atoms is optionally substituted by one or more (a) halogen, (b) —C 1-6 alkyl, or (c) —OC 1-6 alkyl; R 4 is optionally present at one or more of the ring carbon atoms, and each R 4 is selected from the group consisting of (1) halogen, (2) —C 1-6 alkyl, (3) —OC 1-6 alkyl, or (4) hydroxy; and X is CH; or a pharmaceutically acceptable salt thereof.