Patent ID: 7449599

Claim:
A compound of formula (I): wherein R 1 is selected from the group consisting of: wherein R 1a and R 1b are selected from the group consisting of (a) hydrogen, (b) halogen, (c) phenyl, (d) —CN, (e) —C(═O)—R 1c , wherein R 1c is hydrogen or C 1-10 alkyl, (f) —C 3-12 cycloalkyl, and (g) —X—R 1d , wherein X is selected from the group consisting of (i) —O—, (ii) —C(═O)—, (iii) —S—, (iv) —S(═O)—, and (v) —S(═O) 2 —, and R 1d is selected from the group consisting of (i) —C 1-6 alkyl, (ii) —C 1-3 alkoxy, (iii) —C 3-12 cycloalkyl, and (iv) phenyl; or R 1a and R 1b are linked together to form the group —O—CH 2 CH 2 —O— or —CH═CH—CH═CH—; or R 1 is selected from the group consisting of (2) —C(═O)NR 1e R 1f , (3) —OSO 2 R 1g , and (4) —N(R 1g )SO 2 R 1h ; wherein R 1e , R 1f , R 1g and R 1h are independently selected from the group consisting of (a) —C 1-6 alkyl, (b) —C 2-6 alkenyl, (c) —C 2-6 alkynyl, (d) —C 0-6 alkyl-C 3-12 cycloalkyl, (e) —C 1-6 alkyl-di(C 3-12 cycloalkyl), (f) —C 0-6 alkyl-aryl, (g) —C 0-6 alkenyl-aryl, (h) —C 0-6 alkyl-di(aryl), and (i) —C 0-6 alkyl-heteroaryl; wherein said heteroaryl is selected from the group consisting of pyrazinyl, pyrazolyl, pyridazinyl, pyridyl, pyrimidinyl, pyrrolyl, tetrazolyl, furanyl, imidazolyl, triazinyl, pyranyl, thiazolyl, thienyl, thiophenyl, triazolyl, oxazolyl, isoxazolyl, thiazolyl, oxadiazolyl, indolyl, quinolinyl, isoquinolinyl, benzimidazolyl and benzoxazolyl, and said aryl is selected from the group consisting of phenyl and naphthyl, and said alkyl, alkenyl, cycloalkyl, aryl and heteroaryl are unsubstituted or substituted with one or more (i) halo, (ii) —OH, (iii) ═O, (iv) —CN, (v) —CF 3 , (vi) —OCF 3 , (vii) —C 1-6 alkyl, (viii) —C 1-3 alkoxy, (ix) —C 3-12 cycloalkyl, (x) phenyl, (xi) —N 3 , or (xii) —X—R 1d , or R 1e and R 1f are linked with the nitrogen atom to which they are attached to form a 5-7 membered heterocyclic ring, R 2 is selected from the group consisting of (1) hydrogen, and (2) —C 1-6 alkyl; and R 3a , R 3b and R 3c are independently selected from the group consisting of (1) hydrogen, (2) halo, (3) —OH, (4) —CN, (5) —CF 3 , (6) —OCF 3 (7) —C 1-6 alkyl, (8) —C 1-3 alkoxy, (9) —C 3-12 cycloalkyl, and (10) —NHC(═O)CH 2 NR 1a R 1b ; and pharmaceutically acceptable salts thereof, and individual enantiomers and diastereomers thereof.