Patent ID: 7786095

Claim:
An amphiphilic macrocyclic derivative, characterised in that the macrocyclic derivative is a cyclodextrin derivative of the following formula: in which n equals 6-8, and indicates the number of modified glucose units in the macrocycle which are the same or different, depending on the X- and R-groups, X 1 , X 2 , X 3 independently, provide linking groups; R 1 independently, provide groups which are lipophilic; and R 2 and R 3 , independently, provide groups which are polar and/or capable of hydrogen-bonding, and are selected from the group comprising: (CH 2 ) 2-4 OH, CH 2 CH(OH)CH 2 OH, CH 2 CH(OH)CH 2 NH 2 , CH 2 CH 2 NH 2 , a cation, an anion, sulfate, sulfonato, any pharmaceutically acceptable ion, a polyamino acid, a peptide, an oligo-saccharide, and a predominantly hydrophilic group; wherein at least one of R 2 , and R 3 is wholly or in part an oligo/poly(ethyleneoxy) entity.