Patent ID: 8741957

Claim:
A method of improving cognitive function and treating cognitive impairment, the method consisting essentially of administering to a patient in need thereof a therapeutically effective amount of a compound consisting of an alpha-aminoamide of formula (I), wherein: A is a —(CH 2 ) n —X-group, wherein n is an integer of 0 to 5, and X is CH 2 , —O—, —S— or —NH—; s is 1 or 2; R is a furyl, thienyl, pyridyl ring or a phenyl ring, optionally substituted by one or two substituents independently selected from halogen, hydroxy, cyano, C 1 -C 6 alkyl, C 1 -C 6 alkoxy or trifluoromethyl; R 1 is hydrogen or C 1 -C 6 alkyl or C 3 -C 7 cycloalkyl; one of R 2 and R 3 is hydrogen, and the other is C 1 -C 4 alkyl, optionally substituted by hydroxy or phenyl; phenyl, optionally substituted by one or two substituents independently selected from C 1 -C 6 alkyl, halogen, hydroxy, C 1 -C 6 alkoxy or trifluoromethyl; or R 2 and R 3 , taken with the carbon atom which they are linked to, form a C 3 -C 6 cycloalkyl ring; R 4 and R 5 are independently hydrogen, C 1 -C 6 alkyl or C 3 -C 7 cycloalkyl; or R 4 and R 5 , taken together with the nitrogen atom they are linked to, form a 5 to 7 atom saturated heterocyclic ring; and isomers, mixtures, and pharmaceutically acceptable salts or esters thereof.