Patent ID: 8034814

Claim:
A compound of the formula I, wherein r is 1 or 2, n is 0-3, t is 0, 1 or 2, R1 and R2 together form a bridge of subformula 1**, wherein one or two of the ring members T 1 , T 2 , T 3 and T 4 are nitrogen, and the others are in each case CH, and the bond is achieved via atoms T 1 and T 4 ; G is CH 2 ; A is N and B, D, E and T are CH; Q is either lower alkoxy or O, with the proviso that if Q is lower alkoxy, the waved line representing the bonding of Q is a single bond and the ring carrying Q has three double bonds, and if Q is O, the waved line representing the bonding of Q is a double bond and for each Q═O, one of the double bonds in the ring is changed to a single bond; and with the proviso that any Q is bonded to a ring C atom; Q′ is halogen, NHR Q , NR Q 2 , OR Q , SR Q , alkyl, aryl-alkyl, cycloalkyl-alkyl, perfluoroalkyl, acyl, substituted or unsubstituted aryl, or substituted or unsubstituted hetaryl, wherein R Q represents acyl, alkyl, or alkyl substituted by hydroxy, halogen, substituted or unsubstituted aryl, substituted or unsubstituted cycloalkyl or substituted or unsubstituted heterocyclyl; R a and R a ′ are each independently H, halogen or lower alkyl; X is imino, oxa, or thia; and Y is hydrogen, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or unsubstituted or substituted cycloalkyl; or an N-oxide of a compound of formula I, wherein 1 or more N atoms carry an oxygen atom; or a tautomer or mixture of tautomers of a compound of formula I or an N-oxide thereof; or a pharmaceutically acceptable salt of a compound of formula I, of an N-oxide or of a tautomer or mixture of tautomers thereof.