Patent ID: 8211893

Claim:
A method of treating diabetic retinopathy in a subject, comprising: administering a composition comprising a therapeutically effective amount of a protein kinase C zeta inhibitor having the structural formula: where R 1 and R 2 are each independently an alkoxycarbonyl group, a substituted alkoxycarbonyl group, an aryl group or a substituted aryl group, where at least one of R 1 and R 2 is an alkoxycarbonyl group or a substituted alkoxycarbonyl group and at least one of R 1 and R 2 is an aryl group or a substituted aryl group: where R 3 and R 4 are each independently H, a C 1 -C 3 alkyl group, a substituted C 1 -C 3 alkyl group or NHR5 where R 5 is H, acyl or substituted acyl, where at least one of R 3 and R 4 is NHR 5 : a pharmaceutically acceptable salt or hydrate thereof, or a combination of any two or more thereof.