Patent ID: 8877772

Claim:
A compound having Formula (IX): or a pharmaceutically acceptable salt thereof, wherein: Y 3 is chosen from a bond, lower alkyl, lower carboxy, and lower heteroalkyl; R 3 is chosen from phenol and bicyclic heteroaryl, any of which are unsubstituted or substituted with one or more substituents chosen from hydroxy, lower amino, lower amido, lower phenylamido, lower phenylalkylamido, lower heterocycloalkyl, lower alkylheterocycloalkyl; the moiety R 14 —Y 4 —R 2 is chosen from wherein u is 0, 1, 2, or 3; wherein each R 15 is independently chosen from halogen, hydroxy, C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 1 -C 4 haloalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, lower amino, lower amido, lower sulfonamido, and lower sulfonyl, Y 4 is chosen from CHF, CF 2 , —CH 2 —, —CH 2 O—, and —CH 2 N—; and wherein R 14 is chosen from lower cycloalkyl, lower heterocycloalkyl, phenyl, and lower heteroaryl, any of which are unsubstituted or substituted with lower alkyl, lower alkenyl, lower alkynyl, lower alkanoyl, lower heteroalkyl, lower heterocycloalkyl, lower haloalkyl, lower cycloalkyl, phenyl, aryl, aryloxy, lower alkoxy, lower haloalkoxy, oxo, lower acyloxy, carboxy, lower alkylcarbonyl, lower carboxyester, lower carboxamido, halogen, hydroxy, amino, lower alkylamino, arylamino, amido, nitro, thiol, lower alkylthio, lower haloalkylthio, sulfonate, or sulfonic acid.