Patent ID: 7608639

Claim:
The compound having a structural formula III, or a pharmaceutically acceptable salt thereof wherein: A is: a bond, CH 2 , (CH 2 ) 2 , O, S; or A and R 1 or A and R 2 together being a 3- to 6-membered carbocyclyl when A is a carbon; n is: 1, 2, 3, 4, 5 or 6 p is: 1 or 2; r is: 1, 2, 3, or 4; R 1 and R 2 are each independently: hydrogen, C 1 -C 6 alkyl, or R 1 and R 2 together being a 3- to 8-membered carbocyclic ring; R 3 and R 4 are each independently: hydrogen, nitro, cyano, hydroxyl, halo, haloalkyl, haloalkyloxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, or C 3 -C 8 cycloalkyl R 5 is: hydrogen, nitro, cyano, hydroxyl, halo, haloalkyl, haloalkyloxy, aryloxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, [T]-aryl, [T]-heteroaryl, [T]-heterocyclyl, [T]-(CH 2 ) n , C 3 -C 8 cycloalkyl, C(O) p R 7 , O(CH 2 ) n R 7 , SR 7 , S(O) p R 7 or OS(O) p R 7 , wherein aryl, aryloxy, alkyl, heteroaryl, heterocyclyl and cycloalkyl are being optionally substituted with one or more substituents independently selected from R 8 ; [T] is: a bond, O, C(O), S, NR 7 , or C 1 -C 6 alkyl; R 6 is: hydrogen, C 1 -C 6 alkyl or aminoalkyl; R 7 is: hydrogen, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, aryl, heteroaryl or heterocyclyl, wherein alkyl, cycloalkyl, aryl, heteroaryl or heterocyclyl being optionally substituted with one or more substituents independently selected from R 8 ; and R 8 is: hydrogen, nitro, cyano, hydroxyl, halo, haloalkyl, haloalkyloxy, aryloxy, oxo, acyl, C 1 -C 6 alkyl, C 1 -C 6 alkoxy or C 3 -C 8 cycloalkyl.