Patent ID: 8173627

Claim:
A method of reducing infarction volume of an ischemic stroke in a subject having an ischemic stroke, said method comprising: administering to the subject a composition comprising: (a) a bile acid material selected from the group consisting of an ursodeoxycholic acid, an aqueous soluble halo- and/or amino-derivative of an ursodeoxycholic acid, and an ursodeoxycholic acid salt; (b) a carbohydrate selected from the group consisting of an aqueous soluble starch conversion product having at least one reducing end or at least one non-reducing end and an aqueous soluble non-starch polysaccharide; and (c) water, wherein (1) the bile acid material and the carbohydrate both remain in solution for all pH values of the solution between about pH 1 and about pH 14, (2) the bile acid material is at a dosage so that the subject receives from about 25 mg/kg to about 100 mg/kg, (3) the administering comprises administering by a route selected from the group consisting of orally administering, sublingually administering, parenterally administering, intradermally injecting, subcutaneously injecting, intrathyroidally injecting, intravenously injecting, intranasally administering, transdermally administering, and transconjunctivally administering, and (4) infarction volume is reduced.