Patent ID: 8417311

Claim:
A patient treatment and analysis system configured to frequently measure and control the concentration of an analyte in a body fluid of a patient whose insulin sensitivity may be rapidly changing due to trauma or injury, the system comprising: a body fluid analyzer; a fluid network coupled to the body fluid analyzer and configured to: automatically and periodically draw samples of body fluid through a catheter connected to a patient; and transport at least a portion of the samples of body fluid to the body fluid analyzer; the body fluid analyzer configured to: automatically and periodically measure a concentration of an analyte in the samples of body fluid; and access an analyte history and store measured concentrations of the analyte in the analyte history; and a treatment dosing system in communication with the fluid network and the body fluid analyzer, the treatment dosing system comprising: a source of a treatment substance; a treatment dosing algorithm stored in a computer memory; and a dose delivery device configured to automatically and periodically deliver doses to the patient from the source of a treatment substance through the fluid network in response to the treatment dosing algorithm; the treatment dosing system configured to: use the treatment dosing algorithm to calculate an updated estimated insulin sensitivity for the patient more frequently than once per hour, the calculation achieved by accessing the analyte history and a dosage history and comparing portions of the analyte history to portions of the dosage history; use the treatment dosing algorithm to calculate a recommended treatment dosage for the patient more frequently than once per hour, the calculation based at least in part on the updated estimated treatment sensitivity; administer, through the dose delivery device, a dose of the treatment substance to the patient to modify the concentration of the analyte in the body fluid of the patient based at least in part on the updated estimated treatment sensitivity; and access the dosage history and store a record of the administered dose therein.