Patent ID: 8039593

Claim:
An isolated polypeptide comprising an antibody heavy chain variable region (“VH”) and an antibody light chain variable region (“VL”), each variable region having an amino terminus and a carboxyl terminus and comprising four framework regions (“FRs”), which FRs are numbered sequentially FRs 1-4 starting from the amino terminus, and three complementarity determining regions (“CDRs”), which CDRs of each variable region are numbered sequentially CDR1 to CDR3 starting from the amino terminus, wherein (a) CDR1 of said VH has one of the sequences selected from the group consisting of SEQ ID NOs: 22-28, (b) CDR2 of said VH has the sequence of SEQ ID NO:29, (c) CDR3 of said VH has the sequence of SEQ ID NO:30, (d) CDR1 of said VL has the sequence of SEQ ID NO:31, (e) CDR2 of said VL has the sequence of SEQ ID NO:32, and (f) CDR3 of said VL has one of the sequences selected from the group consisting of SEQ ID NO:33-37.