Patent ID: 8722930

Claim:
A compound of formula (I) wherein P 1 is a bond; P 2 is a bond or C 1-3 alkyl; A is CH; B is CH or N; R 1 is —NH—SO 2 —ZR 9 R 13 , —NR 4 —CO—ZR 9 R 13 , —CO—NR 7 R 8 , —CO—O—ZR 9 R 13 , —CO—NR 4 —R X —ZR 9 R 13 , or a group of formula wherein the ring portion in formula (II) is a 5-12 membered saturated, partially saturated, or aromatic ring, which may be monocyclic or bicyclic, and which contains 0, 1, 2, or 3 heteroatoms selected from N, O, S, or combinations thereof; R 3 is —C(NR 17 )NH 2 or amino C 1-7 alkyl; R 10 , R 14 , and R 15 are independently hydrogen, halogen, hydroxy, C 1-7 alkyl, halogen C 1-7 alkyl, or —C(NR 17 )NH 2 ; Q is hydrogen or halogen; R 4 is hydrogen or C 1-7 alkyl; Z is a 5-12 membered saturated, partially saturated, or aromatic ring, wherein said ring is monocyclic or bicyclic, and which contains 0, 1, 2, or 3 heteroatoms selected from N, O, S, or combinations thereof; R 9 and R 13 are independently hydrogen, halogen, hydroxy, carboxy, C 1-7 alkyl, carboxy C 1-7 alkyl, hydroxy C 1-7 alkyl, C 1-7 alkoxycarbonyl, R A NH 2 , or —COR B NH 2 ; R A , R B , and R X are independently a bond or C 1-7 alkyl; R 7 and R 8 are independently hydrogen, amino C 1-7 , alkyl, carboxy C 1-7 alkyl, or C 1-7 alkyl, with a proviso that R 7 and R 8 are not simultaneously hydrogen; R 2 is C 1-7 alkyl, amino C 1-7 alkyl, carboxy C 1-7 alkyl, C 1-7 alkoxycarbonyl C 1-7 alkyl, C 1-7 alkylamino, carboxy C 1-7 alkylamino, R D C(NR 17 )NH 2 , or a group of formula (III) y=0-2; R D is a bond or C 1-7 alkyl; G is CH or N; R 11 is hydrogen, halogen, amino, carboxy, amino C 1-7 alkyl, C 1-7 alkoxycarbonyl, halogen C 1-7 alkoxy, —C(NR 17 )NH 2 , —NHCOR G NH 2 , R J NHCOOR U , or —CONR 19 R 20 ; R G is C 1-7 alkyl; R J is a bond or C 1-7 alkyl; R U is hydrogen or C 1-7 alkyl; R 12 and R 16 are independently hydrogen, halogen or C 1-7 alkyl; or R 12 and R 16 form, together with the carbon atoms to which they are attached, a 5 or 6 membered saturated, partially saturated, or aromatic ring, which contains 0, 1, 2, or 3 heteroatoms selected from N, O, S, or combinations thereof, wherein said ring is substituted or unsubstituted; R 17 is hydrogen, —OH, C 1-7 alkoxy, —O(CO)OR 18 , or —(CO)OR 18 ; R 18 is C 1-7 alkyl; R 19 and R 20 are independently hydrogen, C 1-7 alkyl, or C 1-7 alkoxy; or a pharmaceutically acceptable salt or ester thereof.