Patent ID: 7818154

Claim:
A method for modeling fluorescence of a turbid medium and for using the model to determine intrinsic fluorescence in the turbid medium, the method comprising: illuminating a turbid medium of interest with an electromagnetic radiation source using a probe of a particular geometry that comprises one or more collection fibers and one or more illumination fibers and detecting measured fluorescence for the turbid medium using the probe; running at least one set of Monte Carlo simulations to determine an escape energy probability map and an absorbed energy density map for the turbid medium; and determining, in a manner that accounts for the geometry of the probe using a function that considers the surface areas of the one or more collection fibers and the one or more illumination fibers of the probe and photons escaping the turbid medium, and using the measured fluorescence, the absorbed energy density map, and the escape energy probability map, an indication of intrinsic fluorescence of the turbid medium.