Patent ID: 8389732

Claim:
A compound of Formula A: wherein: n is 1; R 2 is selected from the group consisting of H, alkyl, aryl, alkoxy and halo; R 4 and R 5 are each independently selected from the group consisting of H, alkyl, aryl, heteroaryl, alkenyl, alkynyl, alkoxy, aryloxy, halo, SiR 20 R 21 R 22 , and SnR 20 R 21 R 22 , wherein R 20 , R 21 and R 22 are each independently alkyl, aryl, halo, hydroxy or alkoxy; and R 6 is independently selected from the group consisting of H, C 2 -C 12 alkyl, aryl, heteroaryl, alkenyl, alkynyl, alkoxy, aryloxy, halo, SiR 20 R 21 R 22 , and SnR 20 R 21 R 22 , wherein R 20 , R 21 and R 22 are each independently alkyl, aryl, halo, hydroxy or alkoxy; and R 7 is H or alkyl; subject to the proviso that either R 4 and R 5 , or R 5 and R 6 , together form a fused ring, wherein: when R 5 and R 6 together form a fused ring, said fused ring is selected from the group consisting of: wherein each X is independently selected from the group consisting of C(R′), N, O, SiR′, and S; and when R 5 and R 6 together form a six-membered ring, at least one X is independently selected from the group consisting of N, O, SiR′, and S; and each R′ is independently selected from the group consisting of H, alkyl, aryl, heteroaryl, alkenyl, alkynyl, alkoxy, aryloxy, and halo; or wherein an adjacent pair of R's together form a fused ring selected from the group consisting of: wherein each X′ is independently selected from the group consisting of C(R″), N, O, SiR″, and S; and each R″ is independently selected from the group consisting of H, alkyl, aryl, heteroaryl, alkenyl, alkynyl, alkoxy, aryloxy, halo; and when R 4 and R 5 together form a fused ring, said fused ring is selected from the group consisting of: wherein each X is independently selected from the group consisting of C(R′), N, O, SiR′, and S; and wherein each R′ is independently selected from the group consisting of H, alkyl, aryl, heteroaryl, alkenyl, alkynyl, alkoxy, aryloxy, and halo; or wherein an adjacent pair of R's together form a fused ring selected from the group consisting of: wherein each X′ is independently selected from the group consisting of C(R″), N, O, SiR″, and S; and each R″ is independently selected from the group consisting of H, alkyl, aryl, heteroaryl, alkenyl, alkynyl, alkoxy, aryloxy, and halo; wherein said heteroaryl is selected from the group consisting of: benzofuranyl, benzo[b]thiophenyl, indolyl, indolyl amine, benzoxazolyl, benzoimidazolyl, benzothiazolyl, isoquinolinyl, quinazolinyl, pyridinyl, furanyl, oxazolyl, isoxazolyl, thiazolyl, and imidazolyl; or a pharmaceutically acceptable salt or prodrug thereof.