Patent ID: 8257730

Claim:
A biodegradable intraocular implant comprising a steroid associated with a biodegradable polymer in the form of an intraocular implant, the implant having a steroid release-rate profile, the release-rate profile having a first portion in which the steroid is released substantially independently of a hydrolytic property of the biodegradable polymer, and a second portion in which the steroid release is more dependent on the hydrolytic property of the biodegradable polymer than during the first portion, wherein the biodegradable polymer comprises a combination of a slow degrading poly(D,L-lactide) polymer and a fast degrading poly(D,L-lactide-co-glycolide) polymer, wherein the slow degrading poly(D,L-lactide) polymer has terminal free acid groups and a molecular weight of about 10-20 kD and the fast degrading poly(D,L-lactide-co-glycolide) polymer has a 50:50 D,L-lactide to glycolide ratio, terminal free acid groups, and a molecular weight of about 9-40 kD.