Patent ID: 7049300

Claim:
A regime or regimen for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans, by fibroblasts and/or keratinocytes, comprising administering to an individual in need of such treatment, an effective amount of at least one C-glycoside derivative corresponding to formula (I) below: in which S is a monosaccharide or a polysaccharide containing up to 20 sugar units, in pyranose and/or furanose form and of L and/or D series, said monosaccharide or polysaccharide containing at least one hydroxyl function that is necessarily free and/or optionally one or more optionally protected amine functions; the bond S—CH 2 X is a bond of anomeric-C nature; X is a group consisting of —CO—, —CH(OH)—, —CH(NR 1 R 2 )—, —CHR′—, and —C(═CHR′)—; R is a linear or branched, saturated or unsaturated alkyl, perfluoroalkyl or hydrofluoroalkyl radical, a cycloalkyl, cycloperfluoroalkyl or cyclohydrofluoroalkyl radical containing from 1 to 18 carbon atoms, a phenyl or benzyl radical, said chain, said ring or said radical optionally being interrupted with one or more hetero atoms selected from among oxygen, sulfur, nitrogen and silicon, and optionally substituted with at least one radical selected from among —OR′ 1 , —SR″ 1 , —NR″′ 1 R′ 2 , —COOR″ 2 , —CONHR″′ 2 , —CN, halogen, perluoroalkyl and hydrofluoroalkyl and/or at least one optionally substituted cycloalkyl, aryl or heterocyclic radical, the radicals R′, R 1 and R 2 , which may be identical or different, are each a radical R or a hydrogen atom or a hydroxyl radical; and the radicals R′ 1 , R′ 2 , R″ 1 , R″ 2 , R″′ 1 and R″′ 2 , which may be identical or different, are each a hydrogen atom or a radical selected from among a linear or branched, saturated or unsaturated alkyl radical, hydroxyl, perfluoroalkyl and/or hydrofluoroalkyl radical having from 1 to 30 carbon atoms or a phyflouralkyl and/or acceptable salt or an optical isomer or a geometric isomer thereof, alone or as a mixture in all proportions.