Patent ID: 7094464

Claim:
A multi-layer coated material comprising a substrate, a first layer, a second layer, and a third layer wherein: the substrate comprises a surface-activated porous polymeric material having an average pore size ranging from 1 μm to 200 μm; the first layer consists of polyelectrolyte molecules bound to a surface of the substrate through covalent bonds, electrostatic interactions, or combinations thereof; the second layer consists of polyelectrolyte molecules bound to the first layer through covalent bonds, electrostatic interactions, or combinations thereof; and the third layer consists of molecules of a surfactant directly bound to the second layer through covalent bonds, electrostatic interactions, or combinations thereof; wherein the polyelectrolyte molecules in the first layer and the second layer are different and are independently selected from the group consisting of polyethylenimine, quaternized polyacrylamide, polyvinylamine, polyallylamine, chitosan, poly(acrylate trialkyl ammonia salt ester), cellulose, poly(acrylic acid), polymethylacrylic acid, polyvinylsulfate, poly(styrenesulfonic acid), poly(vinylsulfonic acid), poly(toluene sulfonic acid), heparin, alginic acid, dextran sulfate, adipic acid, poly(methyl vinyl ether-alt maleic acid), surfactant, polyallylammonium chloride, and salts thereof and copolymers thereof.