Patent ID: 7589087

Claim:
A chemical entity that is a compound of Formula (I) or Formula (II): wherein each of R 1-4 is independently H, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, phenyl, —CF 3 , —OCF 3 , —CN, halo, —NO 2 , —OC 1-4 alkyl, —SC 1-4 alkyl, —S(O)C 1-4 alkyl, —SO 2 C 1-4 alkyl, —C(O)C 1-4 alkyl, —C(O)phenyl, —C(O)NR a R b , —CO 2 C 1-4 alkyl, —CO 2 H, —C(O)NR a R b , or —NR a R b ; wherein R a and R b are each independently H or C 1-4 alkyl, n is 1 or 2; Z is N, CH, or C(C 1-4 alkyl); at least one of R 5 and R 5′ is H, and the other is H, methyl, ethyl, ethyl, propyl, isopropyl, —CF 3 , cyclopropyl, or cyclobutyl; R 6 is H, C 1-6 alkyl, or monocyclic cycloalkyl; each of R 7 is H; or both R 7 groups taken together form a carbonyl; R 8 is H or C 1-4 alkyl; R 9 and R 10 are each independently H or C 1-4 alkyl; and R 11 is H or C 1-4 alkyl, with the proviso that where both R 7 groups taken together form a carbonyl, R 11 is not H; a pharmaceutically acceptable salt of compound of Formula (I) or Formula (II), or a pharmaceutically acceptable prodrug of compound of Formula (I) or Formula (II).