Patent ID: 8481733

Claim:
A compound according to Formula I: wherein: A is CH; Q 1 is —X 1 —Y 1 —Z 1 ; or Q 1 is: Y 1 is selected from >C(R 2 )R 3 , >C(OR 2 )R 3 , >C═O, >C═C(R 2 )R 3 , >C═NR 2 , >C═NOR 2 , >NR 2 , >O, or >S(O) m ; and wherein when Y 1 is >O and R 1 is cyclobutyl, at least one of X 1 or Z 1 is substituted; X 1 is phenyl which can be substituted by 1 to 3 independently selected G 1 groups; Z 1 is phenyl which can be substituted by 1 to 3 independently selected G 1 groups; each instance of G 1 is independently selected from halo —CN, —CF 3 , —OCF 3 , —NO 2 , C 1-4 alkyl, phenylC 0-3 alkyl, 5-6 heteroarylC 0-3 alkyl, —OR 4 , —NR 4 R 5 , —C(O)R 4 , —C(O)NR 4 R 5 , —C(O)OR 4 , or —NR 4 C(O)R 5 , any of which can be substituted by 1 to 3 independently selected G 2 groups; each instance of G 2 is independently selected from halo, —CN, —OH, —NH 2 , oxo, —CF 3 , —OCF 3 , or C 1-4 alkyl, an of which can be substituted by 1 to 3 groups independently selected from halo, —CN, —OH, —NH 2 , C 1-4 alkyl (which may be partially or fully halogenated), —N(C 1-6 alkyl)C 1-6 alkyl (which may be partially or fully halogenated), or —OC 1-4 alkyl (which may be partially or fully halogenated); each instance of G 3 is independently selected from halo oxo —CN, —CF 3 , —OCF 3 , C 1-4 alkyl, 5-6 heterocyclicC 0-3 alkyl, phenylC 0-3 alkyl, —OR 8 , —NR 8 R 9 , —C(O)R 8 , —C(O)NR 8 R 9 , —C(O)OR 8 , —NR 8 C(O)R 9 , —(CR 8 R 9 ) n NR 6 R 7 , —(CR 8 R 9 ) n OR 6 , —NR 8 C(O)OR 9 , —O(CR 8 R 9 ) n NR 6 R 7 , —N(CR 8 R 9 ) n OR 6 , or —(CR 8 R 9 ) n NR 6 C(O)OR 7 , any of which can be substituted by 1 to 3 independently selected G 2 substituents; R 1 is selected from C 3-12 alkyl, 3-6 cycloalkyl, phenyl, or 5-6 heterocyclic, any of which can be substituted by 1 to 3 independently selected G 3 groups; each instance of R 2 and R 3 is independently selected from H, halo, or —C 1-6 alkyl; each instance of R 4 and R 5 can be independently selected from H, C 1-4 alkyl, 5-6 cyclicC 0-3 alkyl; and each instance of R 6 , R 7 , R 8 , and R 9 is independently selected from H, C 1-6 alkyl, or 3-6 cyclicC 0-6 alkyl; wherein any R 4 /R 5 , R 6 /R 7 , R 8 /R 9 pair, together with the atom to which they are attached, can form a 3-6 cyclic that can include one or more heteroatoms selected from O, N(C 0-3 alkyl), or S(O) m ; each m is independently selected from 0-2; and each n is independently selected from 0-3; or a pharmaceutically acceptable salt thereof.