Patent ID: 7148247

Claim:
A method of treating or inhibiting prostatitis or interstitial cystitis in a mammal in need thereof, which comprises providing to said mammal an effective amount of a compound of formula I, having the structure wherein R 1 is alkenyl of 2–7 carbon atoms; wherein the alkenyl moiety is optionally substituted with hydroxyl, —CN, halogen, trifluoroalkyl, trifluoroalkoxy, —CORS 5 —CO 2 R 5 , —NO 2 , CONR 5 R 6 , NR 5 R 6 or N(R 5 )COR 6 ; R 2 and R 2a are each, independently, hydrogen, hydroxyl, halogen, alkyl of 1–6 carbon atoms, alkoxy of 1–4 carbon atoms, alkenyl of 2–7 carbon atoms, alkynyl of 2–7 carbon atoms, trifluoroalkyl of 1–6 carbon atoms, or trifluoroalkoxy of 1–6 carbon 10 atoms; wherein the alkyl, alkenyl, or alkenyl moieties are optionally substituted with hydroxyl, —CN, halogen, trifluoroalkyl, trifluoroalkoxy, —COR 5 , —CO 2 R,i —NO 2 , CONR 5 R 6 , NR 5 R 6 or N(R 5 )COR 6 , R 3 , and R 3a are each, independently; hydrogen, alkyl of 1–6 carbon atoms, alkenyl of 2–7 carbon atoms, alkenyl of 2–7 carbon atoms, halogen, alkoxy of 1–4 carbon 15 atoms, trifluoroalkyl of 1–6 carbon atoms, or trifluoroalkoxy of 1–6 carbon atoms; wherein the alkyl, alkenyl, or alkenyl moieties are optionally substituted with hydroxyl, —CN, halogen, trifluoroalkyl, trifluoroalkoxy, —COR 5 , —CO 2 R 5 , —NO 2 ; CONR 5 R 6 , NR 5 R 6 or N(R 5 )COR 6 , R 5 , R 6 are each, independently hydrogen, alkyl of 1–6 carbon atoms, aryl of 6–10 carbon atoms; X is O; or a pharmaceutically acceptable salt thereof.