Patent ID: 8729098

Claim:
A compound selected from those of general formula (I) and pharmaceutically acceptable salts and derivatives thereof, wherein R 2 and R 3 , independently from each other, are selected from: a) —C 1 -C 6 alkyl, with the proviso that R 2 and R 3 are not both methyl, b) —(CH 2 ) n -aryl, 4-halo-benzyl or 4-halo-phenyl, c) —(CH 2 ) n -cycloalkyl, d) —(CH 2 ) n -heterocycle, e) —(CH 2 ) n —OR 6 , f) —(CH 2 ) n —CN, g) —(CH 2 ) n —NR 4 R 5 , h) taken together with the nitrogen atom to which they are attached form a 5- to 8-membered heteromonocycle having from one to three additional heteroatoms selected from the group consisting of oxygen and sulphur, or i) taken together with the nitrogen atom to which they are attached form: (i) a 5- to 8-membered heteromonocycle which is fused to one or two saturated or unsaturated rings or to other heterocycles having from one to three heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur; or (ii) a halo and/or hydroxy substituted dihydroquinoline; R 4 and R 5 , independently from each other, are selected from: a) —H, b) —C 1 -C 6 alkyl, c) —(CH 2 ) n -aryl, d) —(CH 2 ) n -cycloalkyl, e) —(CH 2 ) n -heterocycle, f) —(CH 2 ) n —OR 6 , g) —(CH 2 ) n —CN, h) taken together with the nitrogen atom to which they are attached form a 5- to 8-membered heteromonocycle having from one to three heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur, or j) taken together with the nitrogen atom to which they are attached form a 5- to 8-membered heteromonocycle which is fused to one or two saturated or unsaturated rings or to other heterocycles having from one to three heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur; R 6 is selected from: a) —H, b) —C 1 -C 6 alkyl, c) —(CH 2 ) n -aryl, d) —(CH 2 ) n -cycloalkyl, or e) —(CH 2 ) n -heterocycle; and n is an integer from 0 to 6.