Patent ID: 7087798

Claim:
A method of producing a spirofluorenol compound represented by the following formula (1), by protecting a hydroxyl group bonded to a fluorenone compound represented by the following formula (2), with a protecting group which is a substituted silyl group in which the sum of carbon atoms of substituents bonded to a silicon atom is 5 to 12, then, reacting the fluorenone compound with an organometal compound represented by the following formula (3), wherein M is Li, MgCl, MgBr, MgI or CuLi, to thereby obtain a hydroxy-arylfluorenol of which the hydroxyl group is protected with said protecting group, and transforming the obtained hydroxy-arylfluorenol into a spiro form and removing the protection therefrom, wherein in the above formulas (1) to (3): X is either a single bond or a divalent group selected from the following group A; Y is a group forming an aromatic hydrocarbon cyclic group or an unsaturated heterocyclic group together with two carbon atoms of a benzo ring; when X is a single bond, R 1 and R 2 are, respectively, hydrogen atoms or monovalent groups selected from the following group B, or are bonded together to form a divalent group selected from the following group A (except, -Z- and —CR 5 R 6 —); when X is a group selected from the group A, R 1 and R 2 are, respectively, hydrogen atoms or monovalent groups selected from the following group B; R 3 and R 4 are, respectively, hydrogen atoms or monovalent groups selected from the following group B; and p and q are, independently from each other, integers of 0 to 3; group A: -Z-, —(CR 5 R 6 ) n —, —(CR 5 R 6 ) m -Z-, -Z-(CR 5 R 6 ) l -Z-, —(CR 5 R 6 ) a -Z-(CR 5 R 6 ) b —, —(CR 5 ═CR 6 ) k —, and CR 5 ═N— wherein -Z- is —O—, —S— or —NR 5 —, R 5 and R 6 are, independently from each other, hydrogen atoms, or monovalent groups selected from the following group B, wherein when there are a plurality of -Z-, R 5 or R 6 in one group, the plurality of -Z-, R 5 or R 6 may be different from each other, and a, b, k and 1 are, independently from each other, integers of 1 to 4, and m and n are, independently from each other, integers of 1 to 6; group B: alkyl group, aralkyl group, substituted or unsubstituted aryl group, hydroxy group, alkoxy group, aralkoxy group, amino group, monosubstituted amino group, disubstituted amino group, cyano group, nitro group, halogen atom, trufluoromethyl group, substituted or unsubstituted heterocyclic group having a bond on a carbon atom or on a nitrogen atom, and substituted or unsubstituted condensed heterocyclic group to which aromatic hydrocarbon ring or hetero ring is condensed and having a bond on a carbon atom or on a nitrogen atom.