Patent ID: 8684903

Claim:
A therapeutic method for improving overall microcirculation in organs, for improving hemodynamics, for restoring and preserving deficient endothelial function in a diseased patient, the method comprising: maintaining circulatory flow dynamics of blood in systemic and pulmonary circuits of the diseased patient; and temporarily relieving a pumping function of a heart of the diseased patient; wherein the method further comprises using at least one device external to a body of the diseased patient and connected via a connection element, to: increase a preload of a right ventricle of the heart so as to improve myocardium oxygenation and its contractility; or unload a left ventricle of the heart and diffuse regular pulsatile flow in a proximity of an aortic root of the heart so as to improve hemodynamics of the left ventricle; or stimulate an endothelium of the diseased patient mechanically by shear stress enhancement so as to reduce afterload of the systemic and pulmonary circuits and release several mediators of endothelial vasodilators, in such a manner as to improve microcirculation of main vital organs of the diseased patient by means of the several endothelial vascular vasodilators mediators secreted in particular in response to an application of quasi-physiological tangential forces of shear stresses on endothelial walls of the diseased patient.