Patent ID: 8444983

Claim:
An anti-ENDO180 antibody or an antigen-binding fragment selected from the group consisting of: a. an isolated monoclonal antibody produced by the hybridoma cell line E3-8D8, deposited with the BCCM under Accession Number LMBP 7203CB, or an antigen-binding fragment of such isolated monoclonal antibody; b. a humanized version of the antibody of (a) or an antigen-binding fragment of such humanized version of the antibody of (a); and c. a chimeric version of the antibody of (a) or an antigen-binding fragment of such chimeric version of the antibody of (a); wherein upon contact with a cell expressing ENDO180, the antibody or the antigen-binding fragment binds to the ENDO180 on the surface of the cell and is internalized into the cell.