Patent ID: 7547507

Claim:
A method of diagnosing in a mammal the presence of a breast tumor in which a polynucleotide encoding a polypeptide is significantly upregulated, wherein the polypeptide comprises: (a) the amino acid sequence shown in FIG. 2 (SEQ ID NO:2); (b) the amino acid sequence shown in FIG. 2 (SEQ ID NO:2), lacking its associated signal peptide; (c) the amino acid sequence encoded by the full-length coding sequence of the cDNA deposited under ATCC Accession Number 203127, or (d) the amino acid sequence encoded by the full-length coding sequence of the cDNA deposited under ATCC Accession Number 203127, lacking its associated signal peptide, the method comprising (i) determining the level of expression of the polynucleotide in a test sample of tissue cells obtained from said mammal and (ii) comparing the level of expression of (i) with the level of expression of the polynucleotide in a control sample of known normal cells of the same tissue origin, wherein a significantly higher level of expression of said polynucleotide in the test sample, as compared to the control sample, is indicative of the presence of a breast tumor in which the polynucleotide is significantly upregulated.