Patent ID: 7550458

Claim:
A compound of the following formula I: or a pharmaceutically-acceptable salt thereof; wherein the symbols have the following meanings and are, for each occurrence, independently selected: G is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; Y is O; A 1 and A 2 are each independently CO and/or CHR 1 ; X 1 is CR 1 ; X 2 is CR 1 ; Z 1 and Z 2 are each independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, cycloalkyl, substituted cycloalkyl, cycloalkylalkyl, substituted cycloalkylalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heterocyclo, substituted heterocyclo, heterocycloalkyl, and/or substituted heterocycloalkyl; Q 1 , Q 2 , Q 3 , and Q 4 are each independently H, alkyl, substituted alkyl, aryl,substituted aryl, heterocyclo, and/or substituted heterocyclo; or Q 1 and Q 2 together form ═O; or Q 3 and Q 4 together form ═O; each R 1 and each R 2 are independently H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, cycloalkylalkyl, substituted cycloalkylalkyl, arylalkyl, substituted arylalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, CN, NO 2 , F, Cl, and/or Br; R 3 is H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, cycloalkylalkyl, substituted cycloalkylalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heterocyclo, substituted heterocyclo, heterocycloalkyl, substituted heterocycloalkyl, OH, OR 1 , NR 1 R 2 , —C(═O)R 1 , —C(═O)OR 1 , —SO 2 R 1 , —SOR 1 , —C(═O)NR 1 R 2 , —SO 2 OR 1 , —SO 2 NR 1 R 2 , or —C(═N—CN)—NR 1 R 2 .