Patent ID: 7993888

Claim:
A coryneform bacterium having succinic acid-producing ability, wherein said bacterium is modified so that 2-oxoglutarate dehydrogenase activity is enhanced as compared with the corresponding unmodified bacterium by placing a gene encoding 2-oxoglutarate dehydrogenase under the control of a strong heterologous promoter or by increasing the copy number of said gene, wherein said gene encoding 2-oxoglutarate dehydrogenase has a nucleotide sequence not less than 95% homologous to SEQ ID NO: 3, and wherein the bacterium is further modified so that lactate dehydrogenase activity is decreased by introducing a deletion or insertion in a gene encoding lactate dehydrogenase, and pyruvate carboxylase activity is enhanced by placing a gene encoding pyruvate carboxylase under the control of a strong heterologous promoter or by increasing the copy number of said gene.