Patent ID: 8481584

Claim:
A method for treating cell proliferative disorders, the disorder selected from the group consisting of psoriasis, arthritis, glomerulonephritis, post-surgical stenosis, restenosis, benign hyperplasia, ovarian cancer, breast cancer, colon cancer, colorectal cancer, cervical cancer, bone cancer, thyroid cancer and melanoma, the method comprising: administering to a mammal in need thereof an effective amount of a compound of formula (I) wherein R is an optionally substituted aryl or heteroaryl group; R 1 and R 2 represent, the same or different and independently from each other, a hydrogen atom, a straight or branched C 1 -C 3 alkyl or a group —CONH 2 or —CH 2 NR′R″ or, taken together with the carbon atom to which they are bonded, R 1 and R 2 may form a C 3 -C 6 cycloalkyl group; with the proviso that compounds of formula (I), when one of R 1 and R 2 is hydrogen, the other of R 1 and R 2 is a C 1 -C 3 alkyl and R is 4-(1-methyl-piperazin-4-yl)phenyl, are excluded; R′ and R″ represent, the same or different and independently from each other, a hydrogen atom or a straight or branched C 1 -C 3 alkyl group or, taken together with the nitrogen atom to which they are bonded, R′ and R″ may form a heterocyclic ring of formula wherein R′″ is a hydrogen atom or a straight or branched C 1 -C 3 alkyl group; R 3 is a hydrogen or halogen atom or a group selected from hydroxy, cyano, straight or branched C 1 -C 3 alkyl or C 1 -C 3 alkoxy; or optical isomers, tautomers and pharmaceutically acceptable salts thereof.