Patent ID: 8741558

Claim:
A method for identifying a candidate molecule from a library of tagged chemicals, which comprises the steps of: a) probing a target molecule with a library of chemical compositions, wherein each composition in the library comprises: i) a microscopic bead; ii) a plurality of identical copies of a single-species, sequenceable molecule produced by at least one of BEAMing PCR or bridge amplification, each operably connected to said microscopic bead; and iii) a tag sequence comprising DNA, modified DNA or RNA, which tag sequence is complementary to, and is hybridized to, said sequenceable molecule, iv) a candidate chemical operably connected to said tag sequence, wherein said tag sequence is a unique identifier for its connected candidate chemical; b) isolating each composition which binds to said target molecule; c) sequencing said sequenceable molecule from each said composition; d) identifying, by hybridization under highly stringent conditions, the tag sequence which complements and hybridizes to the identified sequence of said sequenceable molecule; and e) identifying, from a database correlating said tag sequence to its connected candidate chemical, the candidate molecule.