Patent ID: 7955798

Claim:
A method for the electrochemical production of a biopolymer array Comprising a porous membrane and bound biopolymers composed of monomeric, oligomeric or polymeric biopolymer building blocks, comprising the following steps: providing an electrode array comprising selectively addressable electrodes; providing a porous membrane comprising binding sites for biopolymer building blocks, the binding sites bearing protective groups that are electrochemically unstable; providing liquid reagents comprising monomeric, oligomeric or polymeric biopolymer building blocks, said biopolymer building blocks optionally comprise binding sites for bipolymer building blocks bearing protective groups that are electrochemically unstable, bringing said porous membrane into physical contact with said electrode array, performing at least one production cycle comprising: applying an electrical potential to at least one selected electrode of said electrode array, whereby an electrochemical reaction deprotects the protective groups of those binding sites that are arranged above said selected electrodes and that comprise electrochemically unstable protective groups being electrochemically unstable at said applied electrical potential, and bringing said porous membrane and said electrode array into physical contact with said liquid reagents, whereby said monomeric, oligomeric or polymeric biopolymer building blocks of said liquid reagents bind to the electrochemically deprotected binding sites, thereby producing the biopolymer array, and removing the produced biopolymer array comprising said porous membrane and bound biopolymers composed of monomeric, oligomeric or polymeric biopolymer building blocks from said electrode array.