Patent ID: 8330026

Claim:
An isolated NF-KB inducing kinase (NIK) polypeptide fragment that binds to 41 MDD (SEQ ID NO:2) or 44 MPD (SEQ ID NO:17), said fragment selected from the group consisting of: (a) a polypeptide consisting essentially of an amino acid sequence that is at least 75% identical to SEQ ID NO:18, and which binds to 41 MDD or 41 MPD; and (b) a salt or functional derivative of (a) that binds to 41MDD or 44 MPD, said functional derivative being an ester or aliphatic amide of a carboxyl group of the polypeptide or an N-acyl derivative of a free amino group of the polypeptide, or an O-acyl derivative of a free hydroxyl group of the polypeptide, or a derivative obtained by linking the polypeptide to polyethylene glycol, or a combination thereof.