Patent ID: 8183375

Claim:
A compound of the formula: wherein R 1 and R 41 are independently hydrogen or sulfonic acid; R 2 and R 42 are independently selected from the group consisting of hydrogen, cyano, halogen, carboxylic acid, sulfonic acid, C 1 -C 6 alkyl or alkoxy, aryl, heteroaryl, -L-R, and -L-S c , wherein said alkyl or alkoxy is optionally substituted by carboxylic acid, sulfonic acid, or halogen and said aryl or heteroaryl is optionally substituted one or more times by C 1 -C 6 alkyl, C 1 -C 6 perfluoroalkyl, cyano, halogen, azido, carboxylic acid, sulfonic acid, or halomethyl; R 3 , R 4 , R 43 , and R 44 are each methyl; R 5 and R 45 are independently selected from the group consisting of hydrogen, methyl, carboxymethyl, C 1 -C 6 alkyl, aryl, heteroaryl, -L-R x and -L-S c , wherein said alkyl is optionally substituted by carboxylic acid, sulfonic acid, amino, or halogen and said aryl or heteroaryl is optionally substituted one or more times by C 1 -C 6 alkyl, C 1 -C 6 perfluoroalkyl, cyano, halogen, carboxylic acid, sulfonic acid, or halomethyl; R 6 and R 46 are both hydrogen; one of E and X is 0 , S, or NR 8 ; the other is absent; and one of E′ and X′ is O, S, or NR 8 ; the other is absent; wherein R 8 is independently selected from the group consisting of hydrogen, methyl, carboxymethyl, C 2 -C 6 alkyl, -L-R x and -L-S c wherein said alkyl is optionally substituted by carboxylic acid, sulfonic acid, amino, or halogen; and Q is CR 28 , wherein R 28 is of the formula wherein R 30 , R 31 , R 32 , R 33 , and R 34 are independently selected from the group consisting of hydrogen, F, Cl, Br, I, sulfonic acid, carboxylic acid, CN, nitro, hydroxy, azido, amino, hydrazino, C 1 -C 18 alkyl, C 1 -C 18 alkoxy, C 1 -C 18 alkylthio, C 1 -C 18 alkanoylamino, C 1 -C 18 alkylaminocarbonyl, C 2 -C 36 dialkylaminocarbonyl, C 1 -C 18 alkyloxycarbonyl, C 7 -C 18 arylcarboxamido, -L-R x and -L-S c , wherein said alkyl or aryl portions of said R 30 , R 31 , R 32 , R 33 , and R 34 are optionally substituted one or more times by substituents selected from the group consisting of F, Cl, Br, I, hydroxy, carboxylic acid, a carboxylic acid ester of a C 1 -C 6 alcohol, amino, C 1 -C 6 alkylamino, C 1 -C 6 dialkylamino and C 1 -C 6 alkoxy; or a pair of adjacent R 31 , R 32 , R 33 , and R 34 substituents, when taken in combination, form a fused 6-membered aromatic ring that is optionally further substituted by carboxylic acid; and wherein L is a covalent linkage; R x is a reactive group; and S c is a conjugated substance.