Patent ID: 7005254

Claim:
A method for identifying a compound that activates or inhibits cellular proliferation, the method comprising the steps of: (i) contacting the compound with a LETM1 polypeptide, the polypeptide encoded by a nucleic acid that hybridizes under stringent conditions to a nucleic acid encoding a polypeptide having the amino acid sequence of SEQ ID NO:2, wherein the stringent conditions comprise 50% formamide, 5×SSC, and 1% SDS, incubating at 42° C., or in 5× SSC, 1% SDS, incubating at 65° C., with wash in 0.2×SSC, and 0.1% SDS at 65° C.; and (ii) determining the functional effect of the compound upon the LETM1 polypeptide.