Patent ID: 8362008

Claim:
A compound selected from compounds of the following formula, and pharmaceutically acceptable salts thereof: wherein: —R 2 is independently —R 3 is independently —H; —R 5 is independently —H; and ≦Z is independently -J 1 , -J 2 , or -J 3 ; with the proviso that: if: —R 2 is —R 2A , then: —Z is independently -J 2 or -J 3 ; wherein: —R 2A is independently —R 2A1 , R 2A2 or —R 2A3 ; —R 2A1 is independently saturated aliphatic C 1-6 alkyl; —R 2A2 is independently saturated aliphatic C 1-6 alkyl substituted with one or more fluorine atoms; —R 2A3 is independently saturated aliphatic C 1-6 alkyl substituted with —CN; —R 2B is independently —R 2BL -M-R 2BR ; R 2BL is independently saturated aliphatic C 1-4 alkylene; -M- is independently —O; —R 2BR is independently —R 2B1 ; —R 2B1 is independently saturated aliphatic C 1-6 alkyl, and is optionally substituted; —R 2C is independently non-aromatic C 4-7 heterocyclyl, and is optionally substituted; -J 1 is independently a monocyclic non-aromatic heterocyclyl group having from 4 to 8 ring atoms, wherein exactly 1 of said ring atoms is a ring heteroatom, and is N, or exactly 2 of said ring atoms are ring heteroatoms, and are both N, or exactly 2 of said ring atoms are ring heteroatoms, and are N and O, or exactly 2 of said ring atoms are ring heteroatoms, and are N and S, and wherein said non-aromatic heterocyclyl group is optionally substituted; -J 2 is independently a fused bicyclic non-aromatic heterocyclyl group having from 9 to 12 ring atoms, wherein: exactly 1 of said ring atoms is a ring heteroatom, and is N; or exactly 2 of said ring atoms are ring heteroatoms, and are both N; or exactly 2 of said ring atoms are ring heteroatoms, and are N and O; or exactly 2 of said ring atoms are ring heteroatoms, and are N and S; or exactly 3 of said ring atoms are ring heteroatoms, wherein one ring heteroatom is N, and the other two ring heteroatoms are selected from N, O, and S; and wherein said fused bicyclic non-aromatic heterocyclyl group is optionally substituted; and -J 3 is independently a bridged non-aromatic heterocyclyl group having from 7 to 11 ring atoms, wherein exactly 1 of said ring atoms is a ring heteroatom, and is N, or exactly 2 of said ring atoms are ring heteroatoms, and are both N, or exactly 2 of said ring atoms are ring heteroatoms, and are N and O, or exactly 2 of said ring atoms are ring heteroatoms, and are N and S, and wherein said bridged non-aromatic heterocyclyl group is optionally substituted.