Patent ID: 7989477

Claim:
A method for treating cancer in a patient in need thereof, wherein the cancer overexpresses MET receptor, wherein said cancer is colon cancer, kidney cancer, lung cancer, pancreatic cancer or stomach cancer, comprising administering to the patient a therapeutically effective amount of a compound having Formula II: or an enantiomer, diastereomer, or pharmaceutically acceptable salt thereof wherein: each R 2 is independently H, halogen, OR 5 , NR 6 R 7 , alkyl, and/or haloalkyl; B is O, S, SO, or SO 2 ; W is C; X is C; n is zero to 4; R 3 , R 5 , R 6 , and R 7 are independently H and/or alkyl; R 4 is pyridinone or pyridyl-N-oxide substituted with phenyl, fluorophenyl or benzyl; A is R 16 , R 17 , R 18 , and R 19 are H, halogen, NR 30 R 31 , OR 32 , alkyl, hydroxyalkyl, pyridyl, alkenyl, alkynyl, and/or alkynyl substituted with —OH, —NH 2 , —N(alkyl) 2 , or pyridyl, phenyl, phenyl substituted with aminoalkyl; R 30 and R 31 are independently H, alkyl, aminoalkyl, benzyl, methoxybenzyl, phenyl, fluorophenyl, and pyridyl; and R 32 is H or alkyl.