Patent ID: 7351530

Claim:
A method for detecting loss of heterozygosity in chromosome region 11p15.5 in an individual diagnosed with non-small-cell lung cancer (NSCLC) tumor comprising the steps of: a) obtaining tissue samples from the NSCLC tumor and from normal tissue; b) amplifying DNA in the tissue samples from the NSCLC tumor tissue and the normal tissue with a set of primers selected from the group consisting of: set of forward primer SEQ ID NO:3 and reverse primer SEQ ID NO:4, set of forward primer SEQ ID NO:7 and reverse primer SEQ ID NO:8, and set of forward primer SEQ ID NO:9 and reverse primer SEQ ID NO:10, or combinations thereof; c) measuring the amount of amplified products; d) comparing the amount of amplified products from the NSCLC tumor tissue with the amount of amplified products from the normal tissue; e) identifying the NSCLC tumor tissue as having LOH if the amplified products from the NSCLC tumor tissue are less than the amplified products from the normal tissue.