Patent ID: 7384940

Claim:
A method for treating a cancer that expresses functional epidermal growth factor receptors (EGFRs) in a patient resistant or non-responsive to a daily dose of EGFR-tyrosine kinase inhibitor selected from the group consisting of gefitinib and erlotinib, comprising: providing a resistance-surmounting quantity of a kinase inhibitor; and administering the resistance-surmounting quantity of the kinase inhibitor to the patient at a time interval selected from the group consisting of once per week and twice per week, wherein the kinase inhibitor is selected from the group consisting of gefitinib or a pharmaceutically acceptable salt thereof, the resistance-surmounting quantity of the kinase inhibitor is at least 500 mg of the kinase inhibitor and the cancer is a type of cancer selected from the group consisting of prostate cancer, lung cancer, breast cancer, gastric cancer, colorectal cancer, ovarian cancer, and a glioblastoma tumor.