Patent ID: 7812045

Claim:
A compound represented by the following chemical formula 1, an isomer thereof, or a pharmaceutically acceptable salt thereof: wherein, Ar is a phenyl substituted with at least one halogen or C 1 -C 4 haloalkyl; R 1 is hydrogen, one or two fluorine atoms, or C 1 -C 3 lower alkyl; R 2 is hydrogen, halogen, C 1 -C 3 lower alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, nitro, cyano, amino, hydroxy, —NR 3 R 4 , —CONR 3 R 4 , —CH 2 —OCO—R 3 , —CO—R 3 —COOR 3 , —C (═NR 4 )NHR 3 , or —C(═NR 4 )OR 3 ; A is a benzene ring or a 5- or 6-membered heterocyclic ring containing one or more heteroatoms selected from among N, O and S, and may be non-fused or fused with a benzene ring or a 5- or 6-membered heterocyclic ring containing one or more heteroatoms selected from among N, O and S, with no or at least one substituent X therein, X being hydrogen, C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, halogen, nitro, cyano, hydroxy, benzyloxy, hydroxymethyl, —NR 3 R 4 , —NR 3 COR 4 , —NR 3 SO 2 R 4 , —CONR 3 R 4 , —CH 2 —OCO—R 3 , —CO—R 3 , —COOR 3 , —SO z R 3 , —C(═NR 4 )NHR 3 , —C(═NR 4 )OR 3 , or a 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from among N, O and S; R 3 is hydrogen, C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from among N, O and S, —CH 2 COR 4 , —CH 2 CONR 4 or aryl C 1 -C 4 alkyl, the aryl moiety being a phenyl group non-substituted or substituted with at least one halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, nitro, cyano, hydroxy, benzyloxy, phenyl or hydroxymethyl, or being a bicyclic ring in which a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from among N, O and S is fused to a benzene ring; R 4 is hydrogen, C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, —COR 3 , —COCF 3 , —CHR 7 NHR 3 R 4 , —CHR 7 COR 3 , or the same aryl C 1 -C 4 alkyl as defined in R 3 ; R 5 is hydrogen, —CONH 2 , —COCH 3 , —CN, —SO 2 NHR 3 , —SO 2 R 3 , —OR 3 , —OCOR 3 or —(C 1 -C 4 alkyl)-NH 2 ; R 6 is C 1 -C 4 alkyl; R 7 is an α- or β-amino acid residue, whether D or L type, selected from 20 amino acid residues; and z is 0, 1 or 2; wherein the nitrogen atom of position 1 or 2 in the pyrazole ring is bonded to the propanol substituted with the triazole ring, Ar and R 1 .