Patent ID: 7727982

Claim:
A compound of the formula: A-D-E-G-J-K wherein: A is a 5-10 membered saturated monocyclic heterocyclic ring system containing 1-4 heteroatoms selected from N, O and S, wherein 1-2 ring atoms of the heterocyclic ring system are substituted with 1-2 R 1 groups; R 1 is C 1-6 -alkyl; D is phenyl or pyridine where the phenyl is attached to rest of the compound in the 1,4-position and the pyridine is attached to the rest of the compound in the 2,5-position; E is —C(═O)—NH— or —NH—C(═O)—; G is a phenylene group wherein the ring carbon atoms of the phenylene group are substituted with 0-2 R 1d groups and the phenylene group is attached to the rest of the compound at the 1,2-position; R 1d is —(CH 2 ) 0-6 OR 2d ; R 2d is H or C 1-6 -alkyl; J is —C(═O)—NH— or —NH—C(═O)—; K is a phenyl substituted with 0-3 R 1e groups; R 1e is a member independently selected from the group consisting of: halo and —(CH 2 ) 0-2 —O—R 2e ; R 2e is independently a member selected from the group consisting of: H and —C 1-4 -alkyl; or a pharmaceutically acceptable isomer, salt, hydrate, or prodrug derivative thereof.