Patent ID: 6858633

Claim:
An arylbenzazole compound represented by the structural formula 1 below, or a pharmaceutically acceptable salt thereof, wherein X represents S or O; R 1 independently represents fluoro, iodo or trimethyltin; R 2 represents hydrogen, NO 2 , N 3 , halogen, alkyl, a halo substituted or hydroxy substituted alkyl, CN or CF 3 ; R 3 represents hydrogen, halogen, alkyl, or a halo substituted or hydroxy substituted alkyl; R 4 independently represents alkyl, a halo substituted or hydroxy substituted alkyl, hydroxyl, alkoxy or aralkoxy; R 5 and R 6 each independently represent hydrogen, an amino acid, an alkyl, or a group wherein Y represents O or S, and R 7 represents alkyl or —CH(R 8 )NH 2 where R 8 represents hydrogen, or an optionally substituted alkyl; Q represents a direct bond, —CH 2 — or —CH═CH—; p represents zero, 1 or 2; and n represents zero, 1, 2 or 3; subject to the following provisos: (a) alkyl or substituted alkyl groups include linear, branched or cyclic structures but when present as linear or branched structures in the compound or as a moiety in another group such as alkoxy they are composed of less then ten carbon atoms; (b) p represents zero or 1 when n represents 3; (c) when N represents zero, at least one of R 5 or R 6 represents —C(Y)—CH(R 8 )NH 2 ; (d) when a group is optionally substituted, unless otherwise specified, the substituent is selected from one or more of the following: a halogen, OH, SH, NH 2 , COOH and CONH 2 .