Patent ID: 7355051

Claim:
A compound of formula (I) wherein Q is C 1âˆ’6 alkyl optionally substituted with one or more substituents each independently selected from the group consisting of trifluoromethyl, C 3-7 cycloalkyl, Ar 2 , hydroxy, C 1âˆ’4 alkoxy, C 1âˆ’4 alkylthio, Ar 2 -oxy-, Ar 2 -thio-, Ar 2 (CH 2 ) n oxy, Ar 2 (CH 2 ) n thio, hydroxycarbonyl, aminocarbonyl, C 1âˆ’4 alkylcarbonyl, Ar 2 carbonyl, C 1âˆ’4 alkoxycarbonyl, Ar 2 (CH 2 ) n carbonyl, aminocarbonyloxy, C 1âˆ’4 alkylcarbonyl-oxy, Ar 2 -carbonyloxy, Ar 2 (CH 2 ) n carbonyloxy, C 1âˆ’4 alkoxycarbonyl(CH 2 ) n oxy, mono- or di(C 1âˆ’4 alkyl)aminocarbonyl, mono- or di(C 1âˆ’4 alkyl)aminocarbonyloxy, aminosulfonyl, mono- or di(C 1âˆ’4 alkyl)aminosulfonyl or a heterocycle selected from the group consisting of pyrrolidinyl, pyrrolyl, dihydropyrrolyl, imidazolyl, triazolyl, piperidinyl, homopiperidinyl, piperazinyl, pyridyl and tetrahydro-pyridyl, wherein each of said heterocycle may optionally be substituted with oxo or C 1âˆ’6 alkyl; or Q is C 1âˆ’6 alkyl substituted with two substituents wherein one substituent is selected from the group consisting of amino, mono- and diC 1âˆ’4 alkyl-amino and Ar 2 -C 1âˆ’4 alkylamino and the other substituent is selected from the group consisting of carboxyl, C 1âˆ’6 alkyloxycarbonyl, Ar 2 -C 1âˆ’4 alkyloxycarbonyl, aminocarbonyl and aminosulfonyl; wherein Ar 2 is phenyl or phenyl substituted with one substituent selected from the group consisting of halo, hydroxy, C 1âˆ’6 alkyl, hydroxyC 1âˆ’6 alkyl, polyhaloC 1âˆ’6 alkyl, and C 1âˆ’6 alkyloxy; each n is independently 1, 2, 3, or 4; t is 2; G is methylene; R 3b is C 1âˆ’6 alkyl; R 5 is hydrogen; and R1 is 3-hydroxy-6-methylpyrid-2-yl.