Patent ID: 7053113

Claim:
A compound of the formula I: wherein R 3 , R 5 and R 6 are independently selected from the group consisting of hydrogen, alkyl, trihaloalkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, heteroalicyclic, hydroxyl, alkoxy, aryloxy, mercapto, alkylthio, arylthio, sulfinyl, sulfonyl, S-sulfonamido, N-sulfonamido, trihalomethane-sulfonamido, carbonyl, C-carboxy, O-carboxy, C-amido, N-amido, cyano, nitro, halo, O-carbamyl, N-carbamyl, O-thiocarbamyl, N-thiocarbamyl, amino, and —NR 11 R 12 where R 11 and R 12 are independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, carbonyl, acetyl, sulfonyl, trifluoromethanesulfonyl or, R 11 and R 12 , together with the nitrogen to which they are attached, combined form a five- or six-member heteroalicyclic ring; R 7 is hydrogen; R 4 is hydrogen or halo; R 1 ′ is hydrogen or methyl; R 8 and R 10 are independently unsubstituted lower alkyl; R 9 is —C(═O)NHR 13 wherein R 13 is lower alkyl substituted with amino or heteroalicyclic and optionally substituted with hydroxy; and R 3 ′ and R 4 ′, together with the nitrogen atom to which they are attached, form an unsubstituted pyrrolidin-1yl.