Patent ID: 7498338

Claim:
A compound of formula wherein m is 0, 1, 2, 3 or 4; each R 1 independently represents halogen, cyano, hydroxyl, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or sulphonamido; X represents a bond, —CH 2 — or —O—, Y represents a bond, —CH 2 — or —O—, and Z represents a bond, —O—, —NH— or —CH 2 —, provided that only one of X, Y and Z can represent a bond at any one time and provided that X and Y do not both simultaneously represent —O—; n is 0, 1 or 2; each R 2 independently represents halogen, C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; q is 0 or 1; t is 0, 1, 2, 3, 4 or 5; each R 3 independently represents halogen, cyano, nitro, hydroxyl, —C(O)H, —NR 9 R 10 , —CH 2 C(O)NR 11 R 12 , —CH 2 NHC(O)R 13 , —NHSO 2 R 14 , —SO 2 NR 15 R 16 , —CH 2 —R 17 , C 1 -C 6 alkylcarbonyl, phenylcarbonyl, C 3 -C 6 cycloalkyl, or a group selected from C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, phenyl and a saturated or unsaturated 5- to 10-membered heterocyclic ring system comprising at least one ring heteroatom selected from nitrogen, oxygen and sulphur, each group being optionally substituted with at least one substituent selected from halogen, cyano, hydroxyl, carboxyl, C 1 -C 6 alkyl, C 1 -C 6 alkoxy and C 1 -C 6 alkoxycarbonyl; R 4 , R 5 , R 6 , R 7 and R 8 each independently represent hydrogen, halogen, C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; R 9 and R 10 each independently represent hydrogen or C 1 -C 6 alkyl; R 11 and R 12 each independently represent hydrogen or C 1 -C 6 alkyl, or R 11 and R 12 together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring which may be optionally substituted with at least one substituent selected from hydroxyl; R 13 and R 14 each independently represent hydrogen or C 1 -C 6 alkyl; and R 15 and R 16 each independently represent hydrogen or C 1 -C 6 alkyl, or R 15 and R 16 together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring which may be optionally substituted with at least one substituent selected from hydroxyl; R 17 is a 5 to 7 membered saturated heterocyclic ring containing at least one nitrogen atom, which ring may be optionally substituted with one or more oxo groups; or a pharmaceutically acceptable salt thereof.