Patent ID: 8187220

Claim:
An automatic injection device for automatically administering a medicament upon actuation thereof, the device comprising: a housing; a chamber disposed in the housing and having a first compartment and a second compartment, the first compartment containing a first component of the medicament and the second compartment containing a second component of the medicament; a plunger rearwardly sealing the second compartment; a seal structure between the first compartment and the second compartment, the seal structure initially in a sealing condition that seals the first compartment from the second compartment, the seal structure comprising a plug having a solid core and movable within the seal structure to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment through the seal structure, the plug maintaining the same orientation with respect to the seal structure as the plug moves to convert the seal structure from the sealing condition to the mixing condition; a needle assembly connected to the first compartment; and an activation assembly carried by the housing and operatively connected to the plunger, wherein activation of the activation assembly causes (1) the seal structure to convert from the sealing condition to the mixing condition and (2) the first and second medicament components to be mixed and forced through the needle assembly.