Patent ID: 8883413

Claim:
An isolated nucleic acid molecule encoding one or more peptides that inhibits complement activation, wherein the peptide produced by expression of the nucleic acid molecule comprises amino acid sequence: (SEQ ID NO: 15) Xaa1-Cys-Val-Xaa2-Gln-Asp-Trp-Gly-Xaa3-His-Arg- Cys-Xaa4; wherein: Xaa1 is Ile, Val, Leu, or a dipeptide comprising Gly-Ile; Xaa2 is Trp; Xaa3 is His, Ala, Phe or Trp; and Xaa4 is L-Thr, D-Thr, Ile, Val, Gly, or a tripeptide comprising Thr-Ala-Asn; wherein the two Cys residues are joined by a disulfide bond.