Patent ID: 7820195

Claim:
A micronized device for delivery of a therapeutic dose of a biologically active molecule to the eye comprising a capsule, the capsule comprising: a) a core comprising between about 5×10 2 and 90×10 3 living cells that produce a biologically active molecule, wherein the core has a volume of less than 0.5 μl, and b) a biocompatible jacket surrounding said core, the jacket having a molecular weight cutoff permitting diffusion of the biologically active molecule into the eye, wherein the device is configured as a cylinder with an outer diameter of between 200 and 350 μm and a length of between 0.5 and 6 mm, wherein the therapeutic dosage of the biologically active molecule that diffuses into the eye is between 0.1 pg and 1000 ng per eye per patient per day for a period greater than three months.