Patent ID: 8618128

Claim:
A compound, or pharmaceutically acceptable salt thereof, having the structure of Formula I: wherein: R 1 is H; R 2 is independently selected from the group consisting of H and â€”(C 1-9 alkyl) n N(R 9 ) 2 ; R 3 is H; R 4 is independently selected from the group consisting of -aryl(R 13 ) q , -furyl(R 15 ) q , and -thiophenyl(R 15 ) q ; R 5 is H; each R 8 is a substituent attached to the heterocyclyl ring and independently selected from the group consisting of H, halide, and â€”C 1-4 alkyl; each R 9 is independently selected from the group consisting of H, â€”C 1-9 alkyl, â€”(C 1-3 alkyl) n carbocyclyl and â€”(C 1-9 alkyl)N(R 16 ) 2 ; each R 13 is 1-2 substituents each attached to the aryl ring and independently selected from the group consisting of H, halide, â€”(C 1-3 alkyl) n heterocyclyl(R 8 ) q , â€”(C 1-9 alkyl) n N(R 9 ) 2 and â€”(C 1-9 alkyl) n NHSO 2 R 18 ; each R 15 is a substituent attached to the heteroaryl ring and independently selected from the group consisting of H, lower alkyl, halide, â€”CF 3 , CN, and â€”C(â•O)(C 1-3 alkyl); each R 16 is independently selected from the group consisting of H and lower alkyl; each R 18 is a lower alkyl; A is C; each q is independently an integer of 1 or 2; and each n is independently an integer of 0 or 1.