Patent ID: 8809362

Claim:
A method for determining sensitivity of a subject having colorectal cancer to an anti-cancer agent selected from the group consisting of irinotecan, a salt of irinotecan, SN-38, and a salt of SN-38, comprising measuring a level, in a specimen derived from the subject, of at least one substance selected from the group consisting of: a substance detected as an anion at m/z of 149.05 to 149.06; a fragment of a substance detected as an anion at m/z of 149.05 to 149.06; a substance detected as an anion at m/z of 152.99 to 153.00; a fragment of a substance detected as an anion at m/z of 152.99 to 153.00; a substance detected as a cation at m/z of 724.34 to 724.35; a fragment of a substance detected as a cation at m/z of 724.34 to 724.35; glycerol 3-phosphate; dihydrobiopterin; GABA; lactic acid; asparagine; aspartic acid; 2-methylbutyroylcarnitine; 1-methyladenosine; and glutathione; wherein a value of m/z is obtained by mass spectrometry.