Patent ID: 7067541

Claim:
A compound of the formula (1): or a pharmaceutically acceptable salt thereof, wherein the CH 2 —C(═O)NH-benzyl-Q 1 -Q 2 -Q 3 -Q 4 group is substituted on the meta or para position of the benzene ring to which it is attached; R 1 and R 2 are independently H or C 1 –C 4 alkyl; Q 1 is (CH 2 ) n ; Q 2 is —C(═O)NH—, —NHC(═O)—, or —SO 2 NH—; Q 3 is a single bond, C 1 –C 4 alkylenyl optionally substituted with OH, or —(CH 2 ) m —O—(CH 2 ) p —; Q 4 is * represents the attachment point to Q 3 ; R 3 , R 4 , R 5 , R 6 and R 7 are independently H, C 1 –C 4 alkyl, OR 8 , SR 8 , halo, CF 3 , OCF 3 , COOR 9 , SO 2 NR 8 R 9 , CONR 8 R 9 , NHR 8 R 9 , NHCOR 9 , or CH 2 NHC(═O)NHR 9 , provided at least 2 of R 3 , R 4 , R 5 , R 6 and R 7 are H; R 8 is H or C 1 –C 4 alkyl; R 9 is H, C 1 –C 4 alkyl, benzyl optionally substituted with 1, 2, 3 or 4 C 1 –C 4 alkoxy, or n is 0 or 1; m and p are independently 1, 2 or 3; and q is 0, 1, 2 or 3.