Patent ID: 8809770

Claim:
A system for quantitating detectable compounds of a sample, comprising: a processor that receives sample product ion spectra for each mass selection window of a plurality of precursor mass selection windows for each time step of a plurality of time steps, wherein the sample product ion spectra are produced by separating detectable compounds in a sample over time, and at each time step analyzing the detectable compounds by performing a plurality of product ion scans for a plurality of precursor mass selection windows selected across a mass range of the sample using a tandem mass spectrometer; and searches the received product ion spectra for the presence of one or more known compounds with known product ion spectra by: a) retrieving the known product ion spectra from a library, b) retrieving the sample product ion spectra corresponding to the precursor mass selection window expected to contain a precursor ion corresponding to the known product ion spectra, c) generating product ion traces in time for the sample product ion spectra for one or more of the known product ion spectra, d) calculating a score for the product ion traces and product ion spectra that represents how well the known product ions and sample product ions match, and e) calculating a quantitative value for a known compound from the product ion traces when the score exceeds a threshold value.