Patent ID: 7482487

Claim:
A compound of formula (1): wherein the CH 2 —C(═O)NH-benzyl-Q 1 -Q 2 -Q 3 -Q 4 group is in the meta or para position; R 1 and R 2 are independently selected from H and C 1 -C 4 alkyl; Q 1 is —(CH 2 ) n —; n is 0 or 1; Q 2 is selected from —NH—, —C(═O)NH—, —NHC(═O)—, —NH—C(═O)—NH—, and —SO 2 NH—; Q 3 is a single bond or a C 1 -C 4 alkylene optionally substituted with OH; Q 4 is selected from wherein * represents the attachment point to Q 3 ; R 3 , R 4 , R 5 , R 6 and R 7 are independently selected from H, C 1 -C 4 alkyl, phenyl, phenoxy, OR 8 , SR 8 , halo, CN, CF 3 , OCF 3 , COOR 9 , SO 2 NR 8 R 9 , CONR 8 R 9 , NR 8 R 9 , NHCOR 9 and CH 2 —NHC(═O)NH—R 9 ; and R 8 and R 9 are independently selected from H and C 1 -C 4 alkyl; or a pharmaceutically acceptable salt, isomer, tautomer, solvate or isotopic variation thereof.