Patent ID: 7767391

Claim:
A method for determining the likelihood of survival, disease recurrence or response to treatment for a human subject with cancer comprising: (a) hybridizing a polynucleotide complementary to an intronic RNA sequence of a human target gene other than GRB7 or STMY3 to intronic RNA from a tissue sample that has been obtained from the human subject with cancer or a nucleic acid produced therefrom, to form a complex; (b) quantitating the complex to determine the expression level of the human target gene; (c) normalizing the expression level of the human target gene relative to the expression level of one or more reference genes in the tissue sample to determine a normalized expression level of the human target gene; (d) comparing said normalized expression level of said human target gene to data based on normalized expression of the human target gene in cancer tissue samples obtained from patients of known clinical outcome; and (e) determining the likelihood of survival, disease recurrence or response to treatment for the human subject with cancer based on results obtained from step (d).