Patent ID: 7253169

Claim:
A compound of formula I or a pharmaceutically acceptable salt or ester thereof, wherein: n=1-3; R 1 is selected from the group consisting of —C(R 3 ) 3 , —COOR 3 , —COR 3 , —COOH, —SO 3 H, —SO 2 HNR 3 , —PO 2 (R 3 ) 2 , —CN, —PO 3 (R 3 ) 2 , —OR 3 , —SR 3 , —NHCOR 3 , —N(R 3 ) 2 , —CON(R 3 ) 2 , —CONH(O)R 3 , —CONHNHSO 2 R 3 , —COHNSO 2 R 3 , and —CONR 3 CN; R 2 is selected from the group consisting of hydrogen, C 1 -C 9 straight or branched chain alkyl, C 2 -C 9 straight or branched chain alkenyl, C 2 -C 9 straight or branched chain alkynyl, aryl, heteroaryl, carbocycle, and heterocycle, wherein said alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbocycle, and heterocycle is unsubstituted or substituted with one or more substituents selected from R 3 ; R3 is selected from the group consisting of hydrogen, C 1 -C 9 alkyl, C 2 -C 9 straight or branched chain alkenyl, C 2 -C 9 straight or branched chain alkynyl, C 1 -C 9 alkoxy, C 2 -C 9 alkenyloxy, aryloxy, phenoxy, benzyloxy, hydroxy, carboxy, (C 1 -C 9 thioalkyl, C 2 -C 9 thioalkenyl, C 1 -C 9 alkylamino, C 2 -C 9 alkenylamino, cyano, nitro, imino, sulfonyl, sulfhydryl, halo, haloalkyl, trifluoromethyl, aryl, heteroaryl, carbocycle, and heterocycle, wherein said alkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, aryloxy, thioalkyl, thioalkenyl, alkylamino, alkenylamino, aryl, heteroaryl, carbocycle, or heterocycle group is optionally substituted with a hydroxy, carboxy, cyano, nitro, imino, sulfonyl, thiocarbonyl, sulfhydryl, halo, haloalkyl, trifluoromethyl, aryl, heteroaryl, carbocyle, or heterocycle group; and X is O or S, wherein the heteroaryl, carbocycle, and heterocycle are selected from cyclopentyl, cyclohexyl, cycloheptyl, phenyl, benzyl, naphthyl, indenyl, azulenyl, fluorenyl, anthracenyl, indolyl, isoindolyl, indolinyl, benzofuranyl, benzothiophenyl, indazolyl, benzimidazolyl, benzthiazolyl, tetrahydrofuranyl, tetrahydropyranyl, pyridyl, pyrrolyl, pyrrolidinyl, pyridinyl, pyrimidinyl, purinyl, quinolinyl, isoquinolinyl, tetrahydroquinolinyl, quinolizinyl, furyl, thiophenyl, imidazolyl, oxazolyl, benzoxazolyl, thiazolyl, isoxazolyl, isotriazolyl, oxadiazolyl, triazolyl, thiadiazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, triazinyl, trithianyl, indolizinyl, pyrazolyl, pyrazolinyl, pyrazolidinyl, thienyl, tetrahydroisoquinolinyl, cinnolinyl, phthalazinyl, quinazolinyl, quinoxalinyl, naphihyridinyl, pteridinyl, carbazolyl, acridinyl, phenazinyl, phenothiazinyl, phenoxazinyl, adamantly, pyrrole groups, thiophene groups, pyridine groups, and isoxazole groups.