Patent ID: 7517646

Claim:
A process for producing a functional molecule having an affinity to a target, comprising: a forming step which forms a modified nucleotide n-mer (where, n represents an integer) containing a modified nucleoside prepared by introducing a substituent into a nucleoside composing a nucleic acid; a producing step which produces a modified oligonucleotide sequence by randomly polymerizing the modified nucleotide n-mer; a selecting step which selects a sequence having an affinity to a target from the modified oligonucleotide sequences; a determining step which amplifies the selected modified oligonucleotide sequence and determines the base sequence thereof; and a translating step which translates the sequence of the modified oligonucleotide sequence, of which base sequence has been determined, on the basis of a correspondence relation, wherein the correspondence relation relates at least one of 4 n kinds of nucleotide n-mers, which are presented in the correspondence relation prepared by one-to-one combination of 4 kinds of nucleosides, to a modified nucleotide n-mer.