Patent ID: 7572231

Claim:
A method for determining a condition associated with a live body organ by separating desired physiologic signals produced by the live body organ from superimposed signals acquired during physiologic monitoring via a plurality of physiologic signal sensors at different positions in relation to the live body organ, comprising the steps of: acquiring multivariate physiologic signals via the plurality signal sensors, wherein the physiologic signals acquired on each of the signal sensors reflects the respective sensitivity of the particular signal sensor to multiple signal sources, including a desired signal and one or more superimposed contaminant signals; inputting the acquired physiologic signals into a data processor that performs the steps of: converting the acquired physiologic signals into signal data upon which mathematical operations are performed by representing the acquired signal data as an observation vector O(t) whose values are representative of the physiologic signals acquired by the corresponding sensors; accessing a separability operator S that includes a matrix of separation coefficients; applying the separability operator S by dot product to the observation vector O(t) to produce an output; extracting one or more output signals from the output to determine a condition associated with the live body organ; and enabling the physiological monitoring of the condition associated with the live body organ; wherein the matrix of separation coefficients collectively specify a model of the conditions of physiologic and external signal sources encountered during data acquisition.