Patent ID: 7260431

Claim:
An implantable device for delivering cardiac therapy to a patient, comprising: one or more pacing channels for delivering pacing pulses to one or more ventricular sites; a sympathetic inhibition channel for stimulating nerves which inhibit sympathetic nerve activity; a controller for controlling the delivery of pacing pulses to one or more ventricular sites during a cardiac cycle in accordance with a programmed pacing mode; wherein the controller is programmed to deliver remodeling control therapy (RCT) by delivering ventricular pacing in a manner which pre-excites a region of the ventricular myocardium so as to mechanically unload that region during systole; wherein the controller is further programmed to delivery anti-remodeling therapy (ART) in conjunction with RCT by inhibiting sympathetic nerve activity via the sympathetic inhibition channel; means for assessing cardiac function and wherein the controller is programmed to deliver RCT and ART as modulated by an assessment of cardiac function; and, wherein ART is modulated in response to the assessment of cardiac function by varying the duty cycle of neural stimulation pulses.