Patent ID: 6908948

Claim:
A chemical composition comprising an aza-derivative having the structure R 4 R 3 C═XR 1 where X═N or NR 2 where R 1 and R 4 are independently: a substituted-ethynyl group having the structure —C≡C—R 5 , a substituted-allenyl group having the structure —CR 5 ═C═CR 6 R 7 , or a substituted-propargyl group having the structure —CR 5 R 6 —C≡C—R 7 where in each instance R 5 , R 6 , and R 7 are independently hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkyl carbonyl, alkoxy carbonyl, phenyl, aryl, aryl (C 1 -C 4 ) alkyl, hydroxy alkyl, a substituted hydroxyalkyl, an alkyl carboxylic acid derivative, an alkenyl carboxylic acid derivative, an oligonucleic acid, a peptide, a peptoid, an intercalator, a crown ether, a peptide nucleic acid, a DNA alkylating agent, an RNA alkylating agent, a DNA cleaving agent, an RNA cleaving agent, a DNA metalating agent, an RNA metalating agent, a DNA groove binding compound, a porphyrin, an aminoglycoside, a monosaccharide, a disaccharide, or an oligosaccaride, a phosphine oxide, a sulfoxide, a sulfone, a heterocycle substituent, a carbocyclic substituent, one or more aza-derivatives, or where R 5 , R 6 , and R 7 can join with themselves or each other to form a 9-26 membered ring; where R 2 is R 1 , hydrogen, alkyl, phenyl, aryl, aryl (C 1 -C 4 ) alkyl, or a heterocycle substituent; where R 3 is R 1 , alkyl, phenyl, aryl, aryl (C 1 -C 4 ) alkyl, a heterocyclic ring or substituted heterocyclic ring or a group represented by the formula —OR 8 , —SR 8 , or —NR 8 R 9 where R 8 and R 9 are independently hydrogen, alkyl, phenyl, aryl, aryl (C 1 -C 4 ) alkyl, trifluoromethylsulfonyl, silyl, substituted-ethynyl, substituted-allenyl, substituted propargyl, aminosaccharide, a disaccharide, an oligosaccharide, a C-glycoside, an oligonucleic acid, a peptide, a peptoid, an intercalator, a crown ether, a peptide nucleic acid, a DNA alkylating agent, an RNA alkylating agent, a DNA cleaving agent, an RNA cleaving agent, a DNA metalating agent, an RNA metalating agent, a DNA groove binding compound, a porphyrin, an aminoglycoside, or a heterocycle substituent; or where R 2 and R 3 along with parent iminium combine to form a heterocyclic ring.