Patent ID: 8417319

Claim:
A method for imaging neovasculature, the method comprising: acquiring an angiographic image; filtering the angiographic image based on blood vessel diameter for two or more different small blood vessel diameters to identify vasculature of two or more different small blood vessel diameters as neovasculature; computing a density of the identified neovasculature of the different small blood vessel diameters to determine a measured neovasculature density ρ(σ) as a function of small blood vessel diameter σ; and estimating an angiogenesis rate R(t) based on the measured neovasculature density ρ(σ) as a function of small blood vessel diameter σ and a neovasculature growth model t=f(σ) indicating the time t since angiogenesis for neovasculature to grow to vessel diameter σ.