Patent ID: 7144893

Claim:
A compound selected from compounds having the following formula: wherein: Q is ═O or ═N—S(═O) 2 —R Q ; R Q , if present, is —H or optionally substituted C 1-7 alkyl, C 3-20 heterocyclyl, or C 5-20 aryl; Ar is one of the following groups, and is optionally substituted: R N is —H, C 1-7 alkyl, C 3-20 heterocyclyl, or C 5-20 aryl, R O is an oxy substituent and is —H or optionally substituted C 1-7 alkyl, C 3-20 heterocyclyl, C 5-20 aryl, C 1-7 alkyl-acyl, C 3-20 heterocyclyl-acyl, or C 5-20 aryl-acyl; and wherein either (i): the bond marked α is a double bond; the bond marked β is a double bond; R 3 and R 5 are each independently ring substituents selected from: H, halo, —S— C 1-7 alkyl, —S—C 1-7 alkyl-C 5-20 aryl, —S—C 5-20 aryl, and amino acid thioether groups; R 2 and R 6 are H; or (ii): the bond marked α is a single bond or a double bond; the bond marked β is a single bond or a double bond; R 3 and R 5 are each independently ring substituents selected from: H, halo, —S—C 1-7 alkyl, —S—C 1-7 alkyl-C 5-20 aryl, —S—C 5-20 aryl, and amino acid thioether groups; but with the proviso that one or both of R 3 and R 5 is selected from: —S—C 1-7 alkyl, —S—C 1-7 alkyl-C 5-20 aryl, —S—C 5-20 aryl, and amino acid thioether groups; R 2 and R 6 are H; and pharmaceutically acceptable salts, esters, amides, solvates, and hydrates thereof; with the proviso that, if Q is ═O, α is a double bond, β is a double bond, each of R 2 , R 3 , R 5 , and R 6 is —H; and Ar is benzothiazol-2-yl, then R O is other than: -Me, -Et, -Pr, —CH 2 —C≡CH, and —C(═O)CH 3 ; and, with the proviso that, if Q is ═O, α is a double bond, β is a double bond, then Ar is other than: thiophenyl.