Patent ID: 8655798

Claim:
A catheter device for insertion into a vascular structure or body duct, said catheter device having a distal end and a proximal end for delivery of a medium to a lesion, said device comprising: a blood lumen for allowing blood to pass there through; a medium lumen for the delivery of a medium to the lesion, said medium lumen comprising at least one medium egress port for communication with the lesion; an expandable component disposed on said catheter device to block or impede the vascular flow of blood in the vascular structure or body duct; and said blood lumen comprising at least one blood entrance port proximally before said expandable component to allow blood to enter and at least one blood egress port distally beyond said expandable component to allow blood to pass distally beyond said expandable component, wherein, a position of said inlet ports and said exit ports is determined by application of a global optimization algorithm comprising: selecting variables including: a) geometrical shapes and dimensions of at least one of said blood lumen and said medium lumen, b) relative locations and orientations of flow planes of at least one of said blood entrance port and blood egress port, and c) concentration and residence time of the medium in the vicinity of a specific location outside said catheter device; and applying the global optimization algorithm to the variables to generate a catheter with optimized flow conditions.