Patent ID: 8440654

Claim:
A chemical entity selected from the group consisting of compounds of Formula (I) and pharmaceutically acceptable salts of compounds of Formula (I): wherein X is O; R 1 is H, methyl, or bromo; R 2 is H or C 1-4 alkyl; —N(R 3 )R 4 is one of the following moieties, wherein R 3 and R 4 are taken together or separately as defined by each one of said moieties: where q is 0 or 1; p is 0 or 1; r is 0 or 1; R a is H or OH; R b and R c are each independently H or C 1-3 alkyl; R d is H or a C 1-3 alkyl group unsubstituted or substituted with OH or NH 2 ; R e and R f are each methyl, or R e and R f taken together form a methylene or ethylene bridge; and R 5 is H or NH 2 ; provided that when R 1 is H and R 2 is H, methyl, or tert-butyl, then —N(R 3 )R 4 is not 3-aminopyrrolidine, 3-aminopiperidine, piperazine, or N-methylpiperazine.