Patent ID: 7595331

Claim:
Compounds exhibiting CNS activity in mammalian species, said compounds having the formula: wherein A in formulae (I) is B is X is selected from the group consisting of N, —NH—, —NR 4 —, —0—, and —S—; R 4 is C 1-4 alkyl, NH 2, C 1-4 hydroxyalkyl, halogenated C 1-4 alkyl, C 2-4 alkenyl, C 2-4 hydroxyalkenyl, halogenated C 2-4 alkenyl, C 2-4 and alkynyl, and C 2-4 halogenated alkynyl; Y is -NH 2, -OH, =O, or-O-C(O)-R 5 ; 1 is 0, 1, or 2 ; n is 1 or 2; m is 1 or 2; o is 0, 1, 2, 3, or 4; p is 0, 1, 2, 3, or 4; q is 0, 1, 2, or 3; r is an integer from 0 to 5 R, R 1, and R 2 are selected from the group consisting of H, F, Cl, Br, I, CN, COOEt, OH, NO 2, NH 2, OR 5, wherein R 5 is C 1-8 alkyl, C 5-6 cycloalkyl, or C 2-8 alkenyl or R 2 is a 5 or 6 membered heterocycle, and where any carbon of CH 2 m may be substituted by OR 7 where R 7 is C 1-18 alkyl or C 2-18 alkylene, or where R 8 is C 1-18 alkyl or C 2-18 alkylene, or a pharmaceutically acceptable salt or derivative thereof.