Patent ID: 8048443

Claim:
A method for preparing a porous and pliable medical device useful for repairing bone damage and promoting bone formation in mammals, the method comprising the steps of: (a) preparing a quantity of a hydrogel material by mixing (i) a quantity of polymer selected from sodium carboxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl methylcellulose, methylcellulose, and ethylcellulose with (ii) a quantity of glycerin, and (iii) a quantity of water; (b) mixing said hydrogel material with a quantity of anorganic bone mineral particles coated with P-15 peptide to form a putty; and (c) lyophilizing said putty, forming the porous and pliable medical device comprising about 85% (w/w) of said anorganic bone mineral particles coated with P-15 peptide and about 11.5% (w/w) glycerin, wherein prior to step (c) said hydrogel material or said putty is placed under a partial vacuum.