Patent ID: 8063021

Claim:
A compound having a structure according to formula I and the pharmaceutically acceptable salts and esters thereof, wherein m is 0 or 1; X is R 1 is C 1 -C 5 alkyl, C 2 -C 5 alkenyl, C 2 -C 5 alkynyl, aryl, heterocyclo, (heterocyclo)alkyl, biaryl, arylalkyl, arylalkenyl, arylalkynyl, biarylalkyl, biarylalkenyl, or biarylalkynyl; R 2 is H, C 1 -C 5 alkyl, C 2 -C 5 alkenyl, C 2 -C 5 alkynyl, arylalkyl, arylalkenyl, arylalkynyl, biarylalkyl, biarylalkenyl, or biarylalkynyl; or, when m is 0, R 1 and R 2 may combine with the nitrogen to which they are commonly bonded to form a 4, 5, 6, or 7-membered heterocyclic ring structure; R 3 and R 4 are independently H, C 1 -C 5 alkyl, C 2 -C 5 alkenyl, C 2 -C 5 alkynyl, arylalkyl, arylalkenyl, arylalkynyl, biarylalkyl, biarylalkenyl, or biarylalkynyl; R 5 is H or F; and R 6 is H, C 1 -C 5 alkyl, C 2 -C 5 alkenyl, or C 2 -C 5 alkynyl, or R 1 and R 6 may combine with the nitrogen to which they are commonly bonded to form a 4, 5, 6, or 7-membered heterocyclic ring structure.