Patent ID: 8476028

Claim:
A method for determining whether a subject has a bacterial infection comprising: contacting detectably labeled antibodies specific for CD49e, TLR2, and TLR4 with blood leucocytes in a sample obtained from the subject; forming a measurable amount of CD49e-antibody complex, TLR2-antibody complex, and TLR4-antibody complex; identifying abnormal expression of CD49e on blood leucocytes in a sample obtained from the subject from the amount of CD49e-antibody complex; and identifying abnormal expression of one or both of TLR2 and TLR4 on the blood leucocytes in the sample from the amount of TLR2-antibody complex and TLR4-antibody complex, wherein abnormal expression of CD49e and of one or both of TLR2 and TLR4 is indicative of the subject having a bacterial infection.