Patent ID: 8076502

Claim:
A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester compound, or a pharmaceutically acceptable salt thereof, represented by formula [I] wherein, R 1 and R 2 are identical or different, and each represents a C 2-10 alkenyl group, a C 2-10 alkynyl group, a halogenoC 1-10 alkyl group, an azidoC 1-10 alkyl group, an aminoC 2-10 alkyl group, a C 1-10 alkoxycarbonylC 1-10 alkyl group, a farnesyl group, a C 1-10 alkyl group substituted by a group represented by formula-C(O)NR a R b (wherein R a and R b are identical or different, and each represents a hydrogen atom or a C 1-10 alkyl group), a group represented by formula-CHR c OC(O)ZR d (wherein Z represents an oxygen atom, a nitrogen atom, a sulfur atom or a single bond; R c represents a hydrogen atom, a C 1-10 alkyl group, a C 2-10 alkenyl group; and R d represents a C 1-10 alkyl group, a C 2-10 alkenyl group or an aryl group), in the case where either R 1 or R 2 represents a hydrogen atom, the other represents a C 2-10 alkenyl group, a C 2-10 alkynyl group, a C 1-10 alkyl group substituted by one or two phenyl groups substituted by a methoxy group, a fluorine atom or a methyl group, a halogenoC 1-10 alkyl group, an azidoC 1-10 alkyl group, an aminoC 2-10 alkyl group, a C 1-10 alkoxycarbonylC 1-10 alkyl group, a farnesyl group, a C 1-10 alkyl group substituted by a group represented by formula-C(O)NR a R b (wherein R a and R b are the same as described above), a group represented by formula-CHR c OC(O)ZR d (wherein Z, R c and R d are the same as described above), X represents a fluorine atom; and Y is 3,4-dichlorobenzyloxy.