Patent ID: 7323596

Claim:
A compound of formula (I) or (IA) or a pharmaceutical or veterinarily acceptable salt, thereof: wherein: Z represents a radical of formula —N(OH)CH(═O); R 1 represents hydrogen, methyl or trifluoromethyl; R 2 represents a radical of formula R 10 —(X) n —(ALK) m — wherein R 10 represents hydrogen, or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, any of which may be unsubstituted or substituted by (C 1 -C 6 ) alkyl, (C 1 -C 6 )alkoxy, hydroxy, mercapto, (C 1 -C 6 )alkylthio, amino, halo, trifluoromethyl, cyano, intro, oxo, —COOH, —CONH 2 , —COOR A , —NHCOR A , —NR A COR B , —CONHR A , —NHR A , —NR A R B or —CONR A R B wherein R A and R B are independently a (C 1 -C 6 ) alkyl group or R A and R B taken together with the atom(s) to which they are attached form a 5, 6 or 7 membered ring; and ALK represents a straight or branched divalent C 1 -C 6 alkylene, C 2 -C 6 alkenylene, or C 2 -C 6 alkynylene radical, and may be interrupted by one or more non-adjacent —NH—, —O— or —S— linkages, X represents —NH—, —O— or —S—, and m and n are independently 0 or 1; R 3 represents hydrogen, C 1 -C 6 alkyl, or benzyl; R 4 represents (a) aryl or heterocyclic, either of which may be unsubstituted or substituted by cycloalkyl, non aromatic heterocyclyl, methylenedioxy or any of the substituents defined as permitted in R 10 ; or (b) aryl (C 1 -C 6 alkyl)- or heterocyclic(C 1 -C 6 alkyl)-, either which may be unsubstituted or substituted by cycloalkyl, non-aromatic heterocyclyl, methylenedioxy or any of the substituents defined as permitted in R 10 , EXCEPT THAT the (C 1 -C 6 alkyl)- radical in the aryl (C 1 -C 6 alkyl)- or heterocyclic(C 1 -C 6 alkyl)- may not be substituted oxo.