Patent ID: 8603489

Claim:
A composition comprising: a non-allergenic protein preparation, extracted from latex of Hevea brasiliensis ; and material selected from a group consisting of pharmaceutically acceptable vehicles, excipients, stabilizers and combinations thereof, wherein the concentration of the protein preparation in the composition is less than 15 μg/mL, the protein preparation comprising acidic proteins having a negative charge density, and molecular weight less or equal to 60 kDa, wherein the protein preparation is prepared with chromatographic purification of the latex, the protein preparation providing a spectrophotometric absorbance peak at 280 nm upon spectrophotometric monitoring of a chromatograph profile of the protein preparation at 1.5 moles of NaCl when eluted with 0.01 molar ammonium bicarbonate through a diethylaminoethyl cellulose chromatographic column.