Patent ID: 8303956

Claim:
A method of binding an anti-gal antibody to a cancer cell present in a subject comprising: providing an isolated glycoconjugate to a subject that has an anti-gal antibody, wherein said isolated glycoconjugate comprises: a first domain that is a ligand for a receptor on the cancer cell present in said subject or an amino acid sequence of an antibody that binds the cancer cell present in said subject; and a second domain that has at least one Gal α(1,3)Gal saccharide synthetically conjugated to said ligand or said amino acid sequence of an antibody, wherein said at least one Gal α(1,3)Gal saccharide is directly joined to the first domain at one amino acid, such that said first domain binds to said cancer cell and said second domain binds to said anti-gal antibody, thereby generating a complex in said subject that comprises said anti-gal antibody, said glycoconjugate, and said cancer cell.