Patent ID: 8729227

Claim:
A therapeutic composition capable of suppressing appetite, comprising a therapeutically effective amount of a compound together with a pharmaceutically acceptable carrier substance, the compound having the formula: wherein: each X, independently, is an aromatic amino acid other than Trp or any homologs of Trp; each Y, independently, is an amino acid having a guanidino group; each Z, independently, is an aliphatic amino acid; A1 and A2, independently, are selected from Cys, Pen, Glu, Asp, Lys, and Dpr; and wherein the compound optionally includes one or two pseudopeptide bonds where each pseudopeptide bond is independently selected from —CH 2 —NH—, —CH 2 —S—, —CH 2 —CH 2 —, —CH 2 —O— and CH 2 —CO—.