Patent ID: 7759376

Claim:
A compound of Formula (I) wherein Q is O, NR 11 , or S; is a fused ring selected from an aromatic 6-membered ring containing 0 or 1 N atoms; R 1 is independently selected from halo, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, nitro, cyano, (C 1 -C 6 )haloalkyl, (C 1 -C 6 )haloalkoxy, aminocarbonyl, (C 1 -C 6 )alkylaminocarbonyl, bis[(C 1 -C 6 )alkyl]aminocarbonyl, aminosulfonyl, (C 1 -C 6 )alkylaminosulfonyl, bis[(C 1 -C 6 )alkyl]aminosulfonyl, (C 1 -C 6 )alkylcarbonylamino, (C 1 -C 6 )alkylsulfonyl, (C 1 -C 6 )alkylsulfonylamino, hydroxy-(C 2 -C 6 )alkylaminocarbonyl, 1-morpholinylcarbonyl, and 1-piperidinylcarbonyl, and when two of said R 1 substituents are (C 1 -C 6 )alkyl and are attached to adjacent carbon atoms of the Ring A, they may be joined together to form a 5-7-membered carbocyclic ring; n is 0, 1, or 2; R 2 and R 3 are independently selected from hydrogen, halo, hydroxy, (C 1 -C 6 )alkyl, trifluoromethyl, (C 1 -C 6 )alkoxy, and trifluoromethoxy; R 4 is selected from wherein R 6 is H or CH 3 ; and R 7 wherein R 9 is selected from (C 1 -C 6 )alkyl optionally substituted with one or two groups selected from vinyl, CF 3 , OH, methoxy, SCH 3 , NH 2 , —CO 2 H, and —CONH 2 , (CH 2 ) m phenyl wherein m is 0 to 3, and where the phenyl ring is optionally substituted with one or two groups selected from halo, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, OH, nitro, and cyano, piperidinyl optionally substituted on C with halo and optionally substituted on C or N with (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, nitro, or cyano, tetrahydropyran-4-yl; R 10 is H or methyl; or R 9 and R 10 may form, together with the carbon to which they are attached, a 3- to 6-membered carbocyclic ring, R 8 is hydrogen, (C 1 -C 4 )alkyl, hydroxy, or methoxy; R 5 is selected from H, (C 1 -C 6 )alkyl, and hydroxy-(C 2 -C 6 )alkyl; R 11 is selected from H, (C 1 -C 6 )alkyl, and hydroxy-(C 2 -C 6 )alkyl; and the pharmaceutically acceptable salts and esters thereof.