Patent ID: 7279477

Claim:
A compound of the following formula (Ia) or (Ib): wherein R 1 is independently chosen from halo, haloalkyl, hydroxy, thiol, substituted thiol, sulfonyl, sulfinyl, nitro, cyano, amino, substituted amino, C 1 -C 6 alkyl and C 1 -C 6 alkoxy, and when R 1 is hydroxy, C 1 -C 6 alkoxy, thiol, substituted thiol, amino, substituted amino, or C 1 -C 6 alkyl, such radical may be combined with R 2 to form a ring of 5-7 members when R 1 is ortho to R 2 ; R 2 is selected from NR 3 C(S)NR 4 R 5 , NR 3 C(═NR 3 )NR 4 R 5 , NR 3 C(═NCN)NR 4 R 5 , NR 3 C(═CHNO 2 )NR 4 R 5 , NR 3 P(O)R 4 R 5 , NR 3 P(O)(OR 4 )(OR 5 ), NR 3 P(O)(OR 4 )(NR 5 ), NR 3 P(O)(NR 4 )(NR 5 ), NR 3 C(═NR 3 )R 6 , COR 6 , R 6 C(OH)R 7 , CR 8 ═NOR 4 , CR 8 ═NR 3 , CR 8 ═NNR 4 R 5 , SOR 7 , SO 2 R 7 , P(O)(OR 4 )(OR 5 ), P(O)(R 4 )(R 5 ), P(O)(OR 4 )(OR 5 ), P(O)(NR 3 )(OR 4 ), P(O)(NR 4 )(NR 5 ), a 3-7 membered ring containing from zero to three heteroatoms selected from O, N, or S, which may be substituted by R 9 , R 10 , R 11 , R 12 or R 13 , with the exception of the following groups: or may be combined with R 1 to form a ring of 5-7 members when R 1 is ortho to R 2 ; R 3 is hydrogen, alkyl, aryl, heterocyclyl, acyl, or may form a ring of 5-7 members with R 4 or R 5 ; R 4 is hydrogen, alkyl, aryl, heterocyclyl, acyl, or may form a ring of 5-7 members with R 5 or R 3 ; R 5 is hydrogen, alkyl, aryl, or heterocyclyl, acyl or may form a ring of 5-7 members with R 3 or R 4 ; R 6 and R 7 may be equal or different and are selected from hydrogen, alkyl, aryl, or heterocyclyl; R 8 is hydrogen, alkyl, aryl, heterocyclyl, amino or substituted amino; R 9 , R 10 , R 11 and R 12 may be equal or different and are selected from hydrogen, alkyl, aryl, heterocyclyl, nitro, cyano, carboxylic acid, ester, amide, halo, hydroxyl, amino, substituted amino, alkoxy, acyl, ureido, sulfonamido, sulfamido, sulfonyl, sulfinyl, or guanadinyl; R 13 is hydrogen, alkyl, aryl, heterocyclyl, acyl, ester, sulfonyl, ureido, or guanadinyl; A is O, S, or NR 3 ; m is from zero to four; X is H, CF 2 Z, or CF 3 , or together with Y forms a double bond when A is O; Y is hydrogen, or together with X forms a double bond when A is O; and Z is F, Br, Cl, I or CF 3 ; its corresponding enantiomers, diastereoisomers or tautomers; or a pharmaceutically acceptable salt, or a prodrug thereof.