Patent ID: 8252908

Claim:
An isolated monoclonal antibody or binding fragment thereof that binds to a melanocortin-4 receptor or a portion of the melanocortin-4 receptor, wherein said antibody or binding fragment thereof binds to a portion of the melanocortin-4 receptor comprising the amino acid sequence set forth in SEQ ID NO:2, wherein the isolated monoclonal antibody or binding fragment comprises amino acids 24 to 31 of SEQ ID NO:5, amino acids 49 to 56 of SEQ ID NO: 5, amino acids 94 to 107 of SEQ ID NO: 5, amino acids 24 to 34 of SEQ ID NO: 7, amino acids 50 to 57 of SEQ ID NO: 7 and amino acids 89 to 97 of SEQ ID NO: 7.