Patent ID: 8637507

Claim:
A compound, or pharmaceutically acceptable salt of said compound, the compound being represented by the Formula IB or a stereoisomer or tautomer of said compound, wherein the bond denoted by represents a single bond; E is O; F is C(R 4 R 4 ); G is C(R 4 R 4 ); H is N(R 4′ ); R 4 is present depending on the allowed vacancy and is selected from H, alkyl, or hydroxyalkyl; R 4′ is present depending on the allowed vacancy and is R 1 ; R 1 is selected from the group consisting of (alkylamino)carbonyl, (cycloalkylamino)carbonyl, (heterocycloalkylamino)carbonyl, and (arylamino)carbonyl, wherein each of these R 1 groups is unsubstituted or optionally independently substituted with 1-4 substituents independently selected from halogen, amino, alkylamino, hydroxy, alkoxy, alkyl, cycloalkyl, carboxy, carboxyester, methylenedioxy, CN, cyanoalkyl-, nitro and CF 3 ; A is CR 5 ; B is CR 5 ; C is CR 5 ; D is CR 5 ; R 5 is selected from H, alkyl, or halogen, wherein each of these R 5 groups is unsubstituted or optionally independently substituted with 1-4 substituents independently selected from halogen, amino, alkylamino, hydroxy, alkoxy, alkyl, cycloalkyl, CN and CF 3 ; R 2 is heteroaryl, wherein said heteroaryl is a six-membered aromatic ring system containing 1 to 2 N atoms, and wherein said heteroaryl is unsubstituted or optionally independently substituted with 1-4 substituents independently selected from halogen, amino, alkylamino, hydroxy, alkoxy, alkyl, cycloalkyl, CN and CF 3 ; Z is O; and R 3 is selected from the group consisting of alkyl or cycloalkyl.