Patent ID: 7524954

Claim:
A process for the preparation of 5-aminomethyl substituted oxazolidinones of formula I: wherein X is O, S, SO or SO 2 ; R 1 is H, CH 3 or CN; R 2 is independently H, F or Cl; R 3 is H or CH 3 ; n is 0,1 or 2; which comprises; a) reacting a compound of formula II: wherein R 1 , R 3 , X, R 2 and n are as defined in formula I with R-epichlorohydrin of formula III: to produce a compound of formula IV: wherein R 1 , R 3 , X, R 2 and n are as defined in formula I; (b) converting the product of step (a) to chloromethyl oxazolidinone compound of formula V: wherein R 1 , R 3 , X, R 2 and n are as defined in formula I; and (c) converting the chloromethyl oxazolidinone compound of step (b) to aminomethyl oxazolidinone of formula I.