Patent ID: 7790728

Claim:
A compound of formula (I) wherein: A is a monocyclic, polycyclic aryl or heteroaryl group optionally substituted by one or more substituents each independently chosen from halogen atoms, C 1-4 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-4 alkyl, C 1-4 alkoxy, aryl-C 1-4 alkoxy, C 1-4 alkylthio, mono or di-C 1-4 alkylamino, trifluoromethyl, hydroxy and cyano groups; B is a monocyclic nitrogen-containing heteroaryl group optionally substituted by one or more substituents each independently chosen from halogen atoms, C 1-4 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-4 alkyl, aryl, mono or di-C 1-4 alkylamino, trifluoromethyl and cyano groups; and R 1 is a group of formula: -L-(CR′R″) n -G wherein L is a direct bond or a linking group chosen from —(CO)—, —(CO)O—, —(CO)NR′—, SO 2 — and —SO 2 NR′—; R′ and R″ are each independently chosen from a hydrogen atom and C 1-4 alkyl groups; n is an integer from 0 to 6; and G is chosen from a hydrogen atom and C 1-4 alkyl, aryl, heteroaryl, C 3-8 cycloalkyl and saturated or unsaturated heterocyclic groups, wherein the C 1-4 alkyl, C 3-8 cycloalkyl, aryl or heteroaryl groups are each independently unsubstituted or substituted with one or more substituents chosen from halogen atoms, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkylthio, mono or di-C 1-4 alkylamino, trifluoromethyl, trifluoromethoxy, carbamoyl, carboxy and cyano groups; and R 2 is chosen from a hydrogen atom, halogen atoms and C 1-4 alkyl, C 2-5 alkenyl, C 2-5 alkynyl, C 1-4 alkoxy, C 1-4 alkylthio, mono or di-C 1-4 alkylamino, NH 2 , mono or di-C 1-4 alkylamino-(CO)— and cyano groups, wherein the C 1-4 alkyl, C 2-5 alkenyl and C 2-5 alkynyl groups may be each independently unsubstituted or substituted by one aryl or heteroaryl group; or a pharmaceutically acceptable salt thereof, or a N-oxide thereof; with the proviso that the compound is not chosen from N-[6-(1-methyl-1H-indol-3-yl)-5-pyridin-2-ylpyrazin-2-yl]benzamide, N-[3-ethoxycarbonyl-6-(1-methyl-1H-indol-3-yl)-5-pyridin-2-yl-pyrazin-2-yl]-benzamide and N-[3-ethoxycarbonyl-6-(1-methyl-1H-indol-3-yl)-5-pyridin-2-yl-pyrazin-2-yl]-formamide.