Patent ID: 7179832

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof: wherein: n is 0, 1, 2 or 3; R 1 , R 2 and R 3 are each independently hydrogen, hydroxy, halogen or morpholin-1-yl-ethylamino; R 4 is hydrogen; and R 5 is linear or cyclic C 1 –C 6 alkyl optionally having one or more substituents, the carbon of the alkyl being optionally replaced with nitrogen, sulfur or oxygen, wherein the substituent is: hydroxy; halogen; allyloxy; alkyl; amino; alkylamino; carboxyl; nitro; sulfonylamido; alkanesulfonyl; amido; an aromatic group optionally having one or more substituents selected from the group consisting of hydroxy, halogen, alkyloxy, alkyl, amino, alkylamino, carboxyl, nitro, amido, dioxoisoindole and sulfonylamino; an aromatic group having one or more substituents selected from the group consisting of hydroxy, halogen, alkyloxy, alkyl, amino, alkylamino, carboxyl, nitro and amido, the aromatic ring having nitrogen, sulfur or oxygen; or cyclic C 3 –C 8 alkyl optionally having one or more substituents selected from the group consisting of hydroxy, halogen, alkyloxy, alkyl, amino, alkylamino, carboxyl, nitro and amido; an aromatic group optionally having one or more substituents, the aromatic ring having optional nitrogen, sulfur or oxygen, wherein the substituent is; hydroxy; halogen; alkyloxy; alkyl; amino; alkylamino; carboxyl; nitro; sulfonylamido, alkanesulfonyl; amido; or linear or cyclic C 1 –C 6 alkyl optionally having one or more substituents, the alkyl having an optional nitrogen, sulfur or oxygen linkage and the substituent of the alkyl being: hydroxy; halogen; alkyloxy; alkyl; amino; alkylamino; carboxyl; nitro; sulfonylamido, alkanesulfonyl; amido; an aromatic group optionally having one or more substituents selected from the group consisting of hydroxy; halogen; alkyloxy; alkyl; amino; alkylamino; carboxyl; nitro; amido; dioxoisoindole; and a sulfonylamino having an aromatic group substituted with hydroxy, halogen, alkyloxy, alkyl, amino, alkylamino, carboxyl, nitro, sulfonylamido, alkanesulfonyl or amido; an aromatic group optionally having one or more substituents selected from the group consisting of hydroxy, halogen, alkyloxy, alkyl, amino, alkylamino, carboxyl, nitro, sulfonylamide, alkanesulfonyl and amido, the aromatic ring containing nitrogen, sulfur or oxygen; or a cyclic C 3 –C 8 alkyl optionally having one or more substituents selected from the group consisting of hydroxy, halogen, alkyloxy, alkyl, amino, alkylamino, carboxyl, nitro and amido; or R 4 and R 5 form, together with the —N—(CH 2 ) n — moiety to which they are attached, a nitrogen heterocycle optionally having one or more substituents selected from the group consisting of OH, NH 2 , NO 2 , the heterocycle containing optional nitrogen or oxygen.