Patent ID: 8609864

Claim:
A compound of Formula I, or a pharmaceutically acceptable salt thereof: wherein Z is deleted, C(R a R b ), O, S, C(O), N(R a ), SO 2 , OC(O), C(O)O, OSO 2 , S(O 2 )O, C(O)S, SC(O), C(O)C(O), C(O)N(R a ), N(R a )C(O), S(O 2 )N(R a ), N(R a )S(O 2 ), OC(O)N(R a ), N(R a )C(O)O, N(R a )C(O)S, or N(R a )C(O)N(R b ), in which each of R a and R b , independently, is H, alkyl, alkenyl, or alkynyl; m is 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16; and P is in which each of X 1 and X 2 independently, is halo or OSO 2 R c , in which R c is alkyl, alkenyl, or alkynyl; Q is cycloalkyl, heterocycloalkyl, cycloalkenyl, heterocycloalkenyl, aryl, or heteroaryl, each of which, independently, is optionally substituted with alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, cycloalkenyl, heterocycloalkenyl, aryl, heteroaryl, halo, nitro, oxo, —C═NH, cyano, OR d , OC(O)R d , OC(O)OR d , OC(O)SR d , SR d , C(O)R d , C(O)OR d , C(O)SR d , C(O)NR e R f , SOR d , SO 2 R d , NR e R f , or N(R e )C(O)R f , in which each of R d , R e , and R f , independently, is H, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, halo, cyano, nitro, hydroxy, or alkoxy.