Patent ID: 8134013

Claim:
A compound represented by the formula (1), a tautomer thereof, or a pharmaceutically acceptable salt thereof: wherein A is a nitrogen atom or CH, when A is a nitrogen atom, B is NR 9 , wherein R 9 is a C 1-10 alkyl group, and when A is CH, B is a sulfur atom, R 1 is a phenyl group, wherein said phenyl group is substituted with one or more substituents selected from the group consisting of: a halogen atom, an unsubstituted C 1-10 alkyl group, a C 1-10 alkyl group substituted with one or more halogen atom, an unsubstituted C 1-10 alkoxy group, and a C 1-10 alkoxy group substituted with one or more halogen atom, L 1 is a bond, X is OH, R 2 is a C 1-6 alkyl group, L 2 is a bond, L 3 is NH, L 4 is a bond or NH, Y is an oxygen atom or a sulfur atom, and R 3 is a dihydrobenzo[1,4]dioxine group, a benzo[1,4]oxazinone group, and a thienyl group, wherein said thienyl group is substituted with a 2-(4-oxopyridin-1(4H)-yl)acetyl group) or a substituent represented by CONR 29 R 30 , where R 29 is a hydrogen atom or a C 1-10 alkyl group, and R 30 is selected from the group consisting of an unsubstituted amino group, a pyridyl-substituted amino group, a mono-C 1-10 alkylamino group, a di-C 1-10 alkylamino group, a N-methylpiperazinyl group, a piperidino group, a morpholino group, and a C 1-10 alkyl group substituted with one or more substituents selected from the group consisting of: a carboxyl group, a carbamoyl group, a pyrrolidinyl group, a tetrahydrofuryl group and a morpholino group, or R 29 and R 30 mean, together with each other, —(CH 2 ) m3 -G-(CH 2 ) m4 —, wherein G is CR 31 R 32 , wherein R 31 is a hydrogen atom, and R 32 is a C 1-10 alkylcarbonylamino group or a pyrrolidinyl group, and each of m3 and m4 is independently an integer of from 0 to 5, provided that m3+m4 is 3, 4 or 5), or NR 29 R 30 , as a whole, is selected from the group consisting of a di-substituted piperidino group or a di-substituted pyrrolidinyl group, wherein the substitutents independently selected from the group consisting of: a hydroxyl group and a C 1-10 alkoxy group.