Patent ID: 8774925

Claim:
A method of conducing a conditioning modulation of pain perception (CPM), said method comprises: [a] identifying a patient; [b] determining the CPM profile of said patient, comprising: [i] subjecting said patient to a conditioning stimulus (CS); [ii] subjecting said patient to a test stimuli (TS), jointly and severally to said conditioning stimulus (CS), and [iii] rating the intensities of pain sensations evoked by said TS, respectively with and without said CS; and [iv] evaluating the difference between said ratings obtained with and without said CS; thereby assessing the susceptibility of said patient to CPM therapy; [c] selecting at least one site suitable for the delivery of a therapeutic CPM stimulation; wherein said selection is performed in accordance with the Diffuse Noxious Inhibitory Control (DNIC) paradigm; [d] applying said therapeutic CPM stimulation to at least one said suitable site; thereby conducing the conditioning modulation of pain perception (CPM) by said subject, wherein said selecting at least one location suitable for the delivery of a therapeutic CPM stimulation comprises: i. diagnosing said patient for a non-localized pain; ii. Arbitrarily selecting at least one dermatome; iii. Applying a therapeutic CPM stimulation to said dermatome; iv. Empirically evaluating the conduced CPM effect; v. preselecting, in accordance with said DNIC paradigm and based upon said empirical evaluation, a plurality of dermatomes, application of stimulation to which is putatively to conduce a CPM effect; and vi. Selecting from said plurality of preselected dermatomes at least one dermatome overlaying a site that physically/anatomically facilitates an efficient application of said CPM stimulation and/or implantation of an electrical electrode therefore.