Patent ID: 6953809

Claim:
A compound of the formula (B): wherein X 2 is carboxy, —CONHSO 2 CH 3 or —CONHSO 2 -phenyl; Z 2 is hydrogen, fluoro, chloro, bromo, iodo, methyl, trifluoromethyl, hydroxymethyl, acetyl, carboxyC 3-6 cycloalkyl or Z 2 is —(CHR 4 )r—NR 6 R 7 where r is 0-2, R 4 is hydrogen or C 1-4 alkyl R 6 and R 7 are independently selected from H and C 1-4 alkyl or R 6 and R 7 together with the nitrogen to which they are attached form a 5 or 6 membered non-aromatic ring optionally containing one further heteroatom selected from O, N or S; R w and R x are independently halogeno; R y is independently selected from trifluoromethyl, C 1-4 alkyl, halo, hydroxy, C 1-4 alkoxy, C 1-4 alkanoyl, C 1-4 alkanoyloxy, carboxy, trifluoromethoxy, amino, cyano, C 1-4 alkylamino, di(C 1-4 alkyl)amino, C 1-4 alkanoylamino, nitro, carbamoyl, C 1-4 alkoxycarbonyl, thiol, C 1-4 alkylsulphanyl, C 1- alkylsulphinyl, C 1-4 alkylsulphonyl, sulphonamido, carbamoyl C 1-4 alkyl, N-(C 1-4 alkyl)carbamoylC 1-4 alkyl, N-(C 1-4 alkyl) 2 carbamoyl-C 1-4 alkyl, hydroxy C 1-4 alkyl, C 1-4 alkoxyC 1-4 alkyl, morpholino, pyrrolidinyl, carboxy C 1-4 alkylamino, R 3 and —OR 3 (where R 3 is optionally substituted aryl or an optionally substituted 5- or 6-membered heteroaryl ring); and t is 1 or 2, and R y can have the same or different values when t is 2 with the proviso that no more than one R y can be chosen from the group amino, C 1-4 alkylamino, di(C 1-4 alkyl)amino, morpholino and pyrrolidinyl; or a pharmaceutically acceptable salt thereof.