Patent ID: 8501996

Claim:
A self-assembled monolayer solid substrate comprising aminocalixarene as following Formula 5 or 6 and a solid substrate selected from the group consisting of glass, siliconwafer, quartz, and gold, wherein the surface of the glass, silicon wafer, quartz, and gold is functionalized with amine or thiol, wherein the aminocalixarene derivatives are attached to the solid substrate through at least one of the thiol, the aldehyde, and the carboxyl groups of the aminocalixarene: wherein, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R′ 1 , R′ 2 , R′ 3 , R′ 4 , R′ 5 , R′ 6 , R′ 7 , R′ 8 are independently selected from the group consisting of —CH 3 , —C 2 H 5 , —C 3 H 7 , —OCH 3 , —Cl, —C 6 H 5 , —OH, —OCH 2 CH 3 , —Br, —CF 3 , —OCH 2 C 6 H 5 , —OC 6 H 5 , —OC 6 H 4 CH 3 , —OC 6 H 4 C(CH 3 ) 3 , —OC 6 H 4 CF 3 , —OC 6 H 4 Cl, —OCOCH 3 , —NHCOCH 3 , —CONHCH 3 , —CN, COOH, and —COOR, and in said —COOR, R represents —CH 3 or —C 2 H 5 ; wherein R 1 =R 2 =R 3 =R 4 =R 5 =R 6 =R 7 =R 8 , and R′ 1 =R′ 2 =R′ 3 =R′ 4 =R′ 5 =R′ 6 =R′ 7 =R′ 8 , but R 1 ≠R′ 1 ; wherein, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R′ 1 , R′ 2 , R′ 3 , R′ 4 , R′ 5 , R′ 6 , R′ 7 , R′ 8 are independently selected from the group consisting of —CH 3 , —C 2 H 5 , —C 3 H 7 , —OCH 3 , —Cl, —C 6 H 5 , —OH, —OCH 2 CH 3 , —Br, —CF 3 , —OCH 2 C 6 H 5 , —OC 6 H 5 , —OC 6 H 4 CH 3 , —OC 6 H 4 C(CH 3 ) 3 , —OC 6 H 4 CF 3 , —OC 6 H 4 Cl, —OCOCH 3 , —NHCOCH 3 , —CONHCH 3 , —CN, COOH, and —COOR, and in said —COOR, R represents —CH 3 or —C 2 H 5 ; Y 1 , Y 2 , Y 3 and Y 4 are independently selected from the group consisting of —H, —(CH 2 ) n —CH═O, —(CH 2 ) n —SH, —(CH 2 CH 2 O) m —CH 2 CH 2 —CH═O, —(CH 2 CH 2 O) m —CH 2 CH 2 —SH, —(CH 2 ) m —C 6 H 4 (CH 2 ) c —Z, and —CO—(CH 2 ) m-1 —C 6 H 4 —(CH 2 ) c —Z; n=2-15, m=1-10, c=0-10, Z=—SH, —CHO, —COOH, —NH 2 , and —C 6 H 4 — and —C 6 H 5 are phenyl group; wherein R 1 =R 2 =R 3 =R 4 =R 5 =R 6 =R 7 =R 8 , and R′ 1 =R′ 2 =R′ 3 =R′ 4 =R′ 5 =R′ 6 =R′ 7 =R′ 8 , but R 1 ≠R′ 1 .