Patent ID: 8877711

Claim:
A method for detoxifying human plasma, comprising administering extracorporeally to a patient in need thereof an amount of a pasteurized and stabilizer-reduced, but not stabilizer free, albumin preparation, wherein the amount is effective to detoxify plasma, and wherein the albumin preparation is produced by: (i) forming an albumin preparation by adding a sufficient amount of one or more substances that block albumin binding sites such that an adequate number of albumin binding sites are bound to inhibit albumin aggregation during pasteurization, (ii) pasteurizing the albumin preparation, and (iii) removing more than 50% of the one or more substances that block albumin binding sites after pasteurization, wherein aggregation stabilizers are not added to the albumin preparation after pasteurization, and wherein the one or more substances binding albumin comprise octanoate and/or N-acetyl-tryptophan.