Patent ID: 7186714

Claim:
A compound of formula (I): wherein: p is 0, 1, 2 or 3; each R 1 is the same or different and is independently selected from halo, alkyl, Ay, Het, —OR 7 , —NR 7 R 8 , —NR 7 Ay, —NHHet, —NHR 10 Ay and NHR 10 Het: each R 7 and R 8 are the same or different and are independently selected from the group consisting of H, alkyl, cycloalkyl, —C(O)R 9 , —R 10 cycloalkyl, —R 10 OR 9 , —R 10 CO 2 R 9 , and —R 10 NR 9 R 11 ,; each R 9 and R 11 are the same or different and are independently selected from the group consisting of H, alkyl, cycloalkyl, and —R 10 cycloalkyl; each R 10 is the same or different and is independently selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl; Ay is aryl; Het is a 5- or 6-membered heterocyclic or heteroaryl group; R 2 is selected from the group consisting of halo, alkenyl, cycloalkyl, cycloalkenyl, Ay, Het, —OR 7 , —OAy, —OHet, —OR 10 Het, —S(O) n R 9 , —NR 7 R 8 , —NHHet, —NHR 10 Het, —R 10 NR 7 R 8 and —R 10 NR 7 Ay; n is 0, 1 or 2; Y is N R 3 and R 4 are the same or different and are each independently selected from the group consisting of H, halo, alkyl, alkenyl, cycloalkyl, Ay, Het, —OR 7 , —OAy, —C(O)R 7 , —C(O)Ay, —CO 2 R 7 , —CO 2 Ay, —SO 2 NHR 9 , —NR 7 R 8 , —NR 7 Ay, —NHHet, —NHR 10 Het, —R 10 cycloalkyl, —R 10 OR 7 , —R 10 OAy, —R 10 NR 7 R 8 and —R 10 NR 7 Ay; q is 0, 1, 2, 3, 4 or 5; and each R 5 is the same or different and is independently selected from the group consisting of halo, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, Ay, Het, —OR 7 , —OAy, —OHet, —OR 10 Ay, —OR 10 Het, —C(O)R 9 , —C(O)Ay, —C(O)Het, —CO 2 R 9 , —C(O)NR 7 R 8 , —C(O)NR 7 Ay, —C(O)NHR 10 Het, —C(S)NR 9 R 11 , —C(NH)NR 7 R 8 , —C(NH)NR 7 Ay, —S(O) n R 9 , —S(O) 2 NR 7 R 8 , —S(O) 2 NR 7 Ay, —NR 7 R 8 , —NR 7 Ay, —NHHet, —NHR 10 Ay, —NHR 10 Het, —R 10 cycloalkyl, —R 10 Het, —R 10 OR 9 , —R 10 C(O)R 9 , —R 10 CO 2 R 9 , —R 10 C(O)NR 9 R 11 , —R 10 C(O)NR 7 Ay, —R 10 C(O)NHR 10 Het, —R 10 C(S)NR 9 R 11 , —R 10 C(NH)NR 9 R 11 , —R 10 SO 2 R 9 , —R 10 SO 2 NR 9 R 11 , —R 10 SO 2 NHCOR 9 , —R 10 NR 7 R 8 , —R 10 NR 7 Ay, —R 10 NHC(NH)NR 9 R 11 , cyano, nitro and azido; or two adjacent R 5 groups together with the atoms to which they are bonded form a C 5-6 cycloalkyl or aryl; or a pharmaceutically acceptable salt thereof.