Patent ID: 8489334

Claim:
A computer system for evaluating user-supplied genomics data, the system comprising: a computer comprising a structured database to store and access genomics information, wherein the structured database comprises stored genomics information, wherein the computer permits the computation of complex relationships among genes and/or gene products found within the genomics information; wherein the computer is configured to: (a) define one or more profile models based on one or more profile definition criteria; (b) pre-generate a profile library by building a collection of profiles according to the profile models using the genomics information stored in the structured database; (c) receive the user-supplied genomics data; (d) identify one or more overlapped profiles from the profile library that overlap with at least a portion of the user-supplied genomics data; (e) determine, for each of the one or more overlapped profiles, whether the overlap is statistically significant, wherein the determination permits all profiles to be compared in relative terms against each other; and (f) analyze one or more statistically significant overlapped profiles together with the user-supplied genomics data including inspection of database-asserted biological interactions embodied in the one or more statistically significant overlapped profiles; wherein the computer system is a stand alone computer, a multicomponent computer, or a networked computer, and wherein the computer system further comprises hardware for electronically searching the structured database.