Patent ID: 8858981

Claim:
A bone healing material comprising a matrix carrying cultivated bone-forming cells selected from the group consisting of osteocytes, osteoblasts, stromal stem cells and stem cells committed to differentiation into bone-forming osteoblasts, wherein said matrix is selected from a group consisting of (1) a membrane which comprises a sheet of a purified collagen material derived from natural collagen-containing tissue, said membrane comprising a barrier layer including an outer smooth barrier face to inhibit passage of cells therethrough and further including a fibrous face opposite said smooth barrier face, said membrane comprising collagen I, collagen III or a mixture of collagen I and collagen III; (2) a collagen II sheet comprising collagen II having an open texture; and (3) a multi-layer collagen sheet comprising said membrane and said collagen II sheet wherein said collagen II sheet is adhered to said fibrous face of said membrane.