Patent ID: 6916841

Claim:
A compound of the formulae: wherein: R 1 is R 6 is R 7 is selected from C 3 -C 5 cycloalkyl, and phenyl, the rings of these groups being optionally substituted by from 1 to 3 substituents selected from halogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —NH 2 , —NO 2 , —CF 3 , CO 2 H, or —OH; R 2 is selected from H, halogen, —CF 3 , —OH, —C 1 -C 10 alkyl, C 1 -C 10 alkoxy, —CHO, —CN, —NO 2 , —NH 2 , —NH—C 1 -C 6 alkyl, —N(C 1 -C 6 alkyl) 2 , —N—SO 2 —C 1 -C 6 alkyl, or —SO 2 —C 1 -C 6 alkyl; R 3 is selected from H, —CF 3 , —COOH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 3 -C 10 cycloalkyl, —C 1 -C 6 alkyl-C 3 -C 10 cycloalkyl, —CHO, halogen, or a moiety of the formulae: wherein n is independently selected in each appearance as an integer from 0 to 3, Y is C 1 -C 6 alkyl, C 3 -C 5 cycloalkyl, phenyl, benzyl, napthyl, pyridinyl, quinolyl, furyl, thienyl morpholinyl, pyrrolidinyl, or pyrrolyl; rings of these groups being optionally substituted by from 1 to 3 substituents selected from H, halogen, —CF 3 , —OH, —C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —NH 2 , —NO 2 or a five membered heterocyclic ring containing one heteroatom selected from N, S, or O; R 4 is selected from the group of C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —(CH 2 ) n —C 3 -C 6 cycloalkyl, —(CH 2 ) n —S—(CH 2 ) n —C 3 -C 5 cycloalkyl, —(CH 2 ) n —O—(CH 2 ) n —C 3 -C 5 cycloalkyl,or the groups of: a) —(CH 2 ) n -phenyl-O-phenyl, —(CH 2 ) n -phenyl-CH 2 -phenyl, —(CH 2 ) n —O-phenyl-CH 2 -phenyl, —(CH 2 ) n -phenyl-(O—CH 2 -phenyl) 2 , or a moiety of the formulae: wherein n is independently selected in each appearance as an integer from 0 to 3, Y is C 3 -C 5 cycloalkyl, phenyl, benzyl, napthyl, pyridinyl, quinolyl, furyl, thienyl or pyrrolyl; rings of these groups being optionally substituted by from 1 to 3 substituents selected from H, halogen, —CF 3 , —OH, —C 1 -C 6 alkyl, C 1 -C 6 alkoxy, —NH 2 , —NO 2 or a five membered heterocyclic ring containing one heteroatom selected from N, S, or O; n is an integer from 0 to 3; R 5 is R 8 is —COOH, R 9 is H; R 10 is H; or a pharmaceutically acceptable salt thereof.