Patent ID: 6908929

Claim:
A compound of formula (I)(A): wherein both dashed lines complete a carbon-carbon double bond, or both are absent; R 3 is H, C 1-6 alkyl, phenyl, or benzyl; each of R 5 , R 6 , R 7 and R 8 is independently H, C 1-6 alkyl, C 1-6 alkoxy, halo, or amino, with the proviso that R 7 is methyl when both dashed lines complete a carbon-carbon double bond; one of R a , R b , R c , R d , and R e is —WYZ and the others are independently selected from H, C 1-6 alkyl, C 1-6 alkoxy, halo, and amino; W is O—R 9 , wherein R 9 is C 1-6 alkylene, C 2-6 alkynylene, phenylene, or C 2-5 heterocyclic bivalent radical; Y is absent, C 1-6 alkyl, C 2-6 alkynyl, C 2-6 alkenyl, or C 1-6 alkoxy; Z is C 2-8 heterocyclic radical with at least one basic nitrogen atom in the ring, optionally including in the ring up to 3 additional heteroatoms or moieties independently selected from O, C═O, N, NH, NG, S, SO, and SO 2 , wherein G is R 15 , COR 15 , COOR 15 , SO 2 R 15 , SO 2 N or CSR 15 ; and R 15 is C 1-6 alkyl, C 2-6 alkynyl, C 2-6 alkenyl, C 3-7 cycloalkyl, or C 4-7 cycloalkenyl; and each of the above hydrocarbyl or heterocyclic groups being optionally substituted with between 1 and 3 substituents selected from C 1-3 alkyl, halo, hydroxy, C 2-5 heterocyclic radical, phenyl, and phenyl(C 1-3 alkyl); and wherein each of the above heterocyclic groups may be attached to the rest of the molecule by a carbon atom or a heteroatom; or a pharmaceutically acceptable salt, amide, ester, or hydrate thereof.