Patent ID: 7741456

Claim:
A compound of the formula: including the isolated stereoisomeric forms thereof; wherein R* is a ethyl substituted at position 2 or methyl each substituted by F, Cl, Br, N 3 , OH, O-alkyl, S-alkyl, CN, O-acyl, O-aryl, NH 2 , NH-alkyl or N(alkyl) 2 ; or wherein R* is ethyl substituted at position 1 by F, and position 2 is unsubstituted or substituted by Br, I, OH, O-alkyl, O-aryl, N 3 , CN, S-alkyl, or S-aryl; or is substituted both at the 1 and 2 positions by OH, or positions 1 and 2 are included in a ring wherein the bridge between positions 1 and 2 is —O—, —NH—, or —N-alkyl-; or wherein R* is vinyl substituted at position 1 by F, Cl or Br; or wherein R* is C(O)H, C(O)OH, C(O)O-alkyl, C(O)O-aryl, CONH 2 , CONH-alkyl, CON-(alkyl) 2 or CONH-aryl; each of R 1 -R 6 is independently H or alkyl (1-4C) wherein any alkyl at R 1 may optionally be substituted; each of X 1 -X 5 is independently H 2 , HOH or ═O; or each of X 1 -X 5 is independently H and the compound of formula (6) contains a π-bond in the ring adjacent to the position of said X at 2-3, 4-5, 6-7, 8-9 and/or 10-11; wherein at least two of R 1 -R 6 are alkyl (1-4C); and wherein any OH included in X 4 may be further substituted with desosamine and/or X 5 may be further substituted with cladinose.