Patent ID: 7524870

Claim:
A compound of formula (I) wherein Ar is an aromatic heterocyclic ring selected from a thiazolyl or pyridinyl ring; Ar 2 is a substituted or unsubstituted cyclic ring selected from the group consisting of benzo[1,3]dioxol-5-yl, furan-2-yl, isoquinolin-5-yl, isoxazol-4-yl, 1-naphthyl, pyrazol-1-yl, pyrazol-4-yl, pyridin-3-yl, thiophen-2-yl, thiophen-3-yl and phenyl and where substituted the substituents are selected from the group consisting of acetamido, aminocarbonyl, benzyl, benzyloxy, halogen, hydroxyl-lower alkyl, lower alkyl, lower alkoxy-lower alkyl, phenoxy, phenyl, lower alkoxy and trifluoro-methoxy; R 2 and R 3 are independently selected from the group consisting of lower alkyl, lower alkoxy, trifluoromethyl, halogen, hydroxy, amino, alkylamino, diakylamino, cyano and nitro; R 4 is hydroxy or an amino acid attached through a nitrogen atom of the amino acid; m is 0,1,2, 3 or 4; p is 0, 1 or 2, and s is 0, 1, or 2, provided that when Ar 2 is phenyl, the phenyl ring is substituted by at least one substituent selected from the group consisting of acetamido, aminocarbonyl, benzloxy, hydroxyl-lower alkyl, lower-alkoxy-lower alkyl, phenoxy, phenyl, pyrazol-1-yl and trifluoromethoxy and when Ar 2 is substituted phenyl, there are not two lower alkyl substituents ortho to the point of attachment of the Ar 2 ring to the adjacent phenyl ring or a pharmaceutically acceptable salt thereof.