Patent ID: 7763619

Claim:
A method for treating a disorder of the outer retina in a patient suffering from such a disorder, which comprises administering a pharmaceutically effective amount of a compound with 5-HT 1A agonist activity to the eye of said patient, wherein the compound is selected from the group consisting of: tandospirone, ziprasidone, repinotan hydrochloride, xaliproden hydrochloride (SR-57746A), buspirone, flesinoxan, 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide (EMD-68843), bifeprunox mesylate (DU-127090), gepirone, alnespirone, (R)-5,6-dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2-(1H)-one (Z)-2-butenedioate maleate (PNU-95666), [N-piperonyl-2-amino-1,2,3,4-tetrahydrobenzo(b)thieno(2,3-c)pyridine]-3-carbamide hydrochloride (AP-521), flibanserin, 5-{3-[((2S)-1,4-benzodioxan-2-ylmethy)amino]propoxy}-1,3-benzodioxole HCl (MKC-242), lesopitron, sarizotan hydrochloride, 4-(4-fluorophenil)-1,2,3,6-tentrahydro-1-[4-(1,2,4-triazol-1-il)butyl]pyridine citrate (E-5842), 3-chloro-4-[4-[4-(2-pyridinyl)-1,2,3,6-tetrahydropyridin-1-yl]butyl]-1,4-benzoxazepin-5(4H)-one (SUN-N4057), 1-(4-trifluoromethyl-2-pyridinyl)-4-[4-[2-oxo-1-pyrrolidinyl]butyl]piperazine (E)-2-butenedioate (Org-13011), and 8-OH-DPAT, and wherein the disorder is selected from the group consisting of: age-related macular degeneration (AMD), retinitis pigmentosa (RP), retinal detachment, retinal tears, macular pucker, ischemia affecting the outer retina, diabetic retinopathy, damage associated with laser therapy (grid, focal, and panretinal) including photodynamic therapy (PDT), retinal trauma, surgical or light-induced iatrogenic retinopathy, and preservation of retinal transplants.