Patent ID: 7728130

Claim:
A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: n is 1; R 1 is chosen from H, lower alkyl and substituted lower alkyl; R 2 is H; R 3 and R 4 are each H; R 5 is chosen from OH, SH, NH 2 , lower alkyl, substituted lower alkyl, lower alkoxy, substituted lower alkoxy and sulfanyl; R 6 is OH; and each of R 7 , R 8 , R 9 and R 10 is independently chosen from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, NR 3′ R 4′ , C(O)OH, OR 13 , SR 13 , SO 2 R 13 , CN, NO 2 , halo, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heteroarylalkyl, substituted heteroarylalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkylsilyl, substituted alkylsilyl, alkynylsilyl, substituted alkynylsilyl, alkoxy, substituted alkoxy, alkoxycarbonyl, substituted alkoxycarbonyl, and —X—R 12 , wherein: R 3′ and R 4′ are independently chosen from H, lower alkyl, substituted lower alkyl, lower haloalkyl, substituted lower haloalkyl; X is chosen from —N(R 11 )—Y and —Y—N(R 11 )—; Y is chosen from C(O), SO 2 , alkylene, substituted alkylene, alkenylene, substituted alkenylene, alkynylene, and substituted alkynylene; R 11 is chosen from H, lower alkyl, and substituted lower alkyl; R 12 is chosen from H, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; and R 13 is chosen from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl and substituted alkynyl; wherein optionally at least one of adjacent pairs R 7 and R 8 , R 8 and R 9 , and R 9 and R 10 , join together to form a 4 to 7 membered ring or a substituted 4 to 7 membered ring.