Patent ID: 6951874

Claim:
A compound of general formula m is 0, 1, 2 or 3; each R 1 independently represents halogen, cyano, nitro, carboxyl, hydroxyl, C 3 -C 6 cycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy, —NR 9 R 10 , C 3 -C 6 cycloalkylamino, C 1 -C 6 alkylthio, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkylcarbonylamino, sulphonamido, C 1 -C 6 alkylsulphonyl, —C(O)NR 11 R 12 , —NR 13 C(O)—(NH) p R 14 , phenyl, or C 1 -C 6 alkyl optionally substituted by carboxyl or C 1 -C 6 alkoxycarbonyl; p is 0 or 1; X represents an oxygen or sulphur atom or a CH 2 , CH(CH 3 ), OCH 2 , CH 2 O, CH 2 NH, NH or carbonyl group and Y represents a CH group; Z 1 represents a bond or a group (CH 2 ) q where q is 1 or 2; Z 2 represents a bond or a group CH 2 , with the proviso that Z 1 and Z 2 do not both simultaneously represent a bond; Q represents an oxygen or sulphur atom or a group CH 2 or NH; R 2 represents a group n is 0, 1 or 2; each R 3 independently represents a C 1 -C 6 alkyl, C 1 -C 6 alkoxycarbonyl, —CH 2 OH or carboxyl group; R 4 , R 5 , R 6 and R 7 each independently represent a hydrogen atom or a C 1 -C 6 alkyl group, or R 4 , R 5 , R 6 and R 7 together represent a C 1 -C 4 alkylene chain linking the two carbon atoms to which they are attached to form a 4- to 7-membered saturated carbocycle, or R 5 , R 6 and R 7 each represent a hydrogen atom and R 4 and R 8 together with the carbon atoms to which they are attached form a 5- to 6-membered saturated carbocycle; R 8 represents a hydrogen atom, a C 1 -C 6 alkyl group or is linked to R 4 as defined above; R 9 and R 10 each independently represent a hydrogen atom or a C 1 -C 6 alkyl group, or R 9 and R 10 together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocycle; R 11 and R 12 each independently represent a hydrogen atom or a C 1 -C 6 alkyl group optionally substituted by C 1 -C 6 alkoxycarbonyl; R 13 represents a hydrogen atom or a C 1 -C 6 alkyl group; and R 14 represents a hydrogen atom, or a C 1 -C 6 alkyl group optionally substituted by carboxyl, C 1 -C 6 alkoxy or C 1 -C 6 alkoxycarbonyl; provided that when X is an oxygen atom or a group CH 2 , Y is CH, Z 1 and Z 2 each represent a group CH 2 and Q is an oxygen atom, then R 2 is other than an unsubstituted indolyl group; or a pharmaceutically acceptable salt or solvate thereof.