Patent ID: 7598423

Claim:
A compound of formula I wherein R 1 is selected from the group consisting of C1-C5 alkyl, C3-C7 cycloalkyl, C4-C8 cycloalkylalkyl, phenyl and substituted phenyl; R 2 is selected from the group consisting of hydrogen, C1-C5 alkyl, substituted C1-C5 alkyl, halo, phenyl, substituted phenyl, C1-C3 fluoroalkyl, CN, CO 2 R 3 , thiophenyl, substituted thiophenyl, thiazolyl, substituted thiazoyl, furanyl, substituted furanyl, pyridinyl, substituted pyridinyl, oxazolyl, substituted oxazloyl, isothiazolyl, substituted isothiazoyl, isoxazolyl, substituted isoxazolyl, 1,2,4-oxadiazolyl, substituted 1,2,4-oxadiazolyl, pyrimidinyl, substituted pyrimidinyl, pyridazinyl, and substituted pyridazinyl; X is selected from the group consisting of O, S(O) m , and NR 3 ; Y is selected from the group consisting of C1-C3 alkanediyl and substituted C1-C3 alkanediyl; Ar 1 and Ar 2 are independently selected from the group consisting of phenylene and substituted phenylene; L is selected from the group consisting of C1-C5 alkanediyl, substituted C1-C5 alkanediyl, and —G—C(═W)—J—; W is CR 3 R 3 , O or NR 3 ; G and J are independently selected from the group consisting of a bond and C1-C3 alkanediyl; R 3 is independently hydrogen or C1-C5 alkyl; Z is selected from the group consisting of (CH 2 ) n COOH, m is 0, 1, or 2; n and q are independently 0, 1, 2 or 3; and pharmaceutically acceptable salts thereof.