Patent ID: 8829003

Claim:
A compound of formula I: or a pharmaceutically acceptable salt or solvate or physiologically hydrolysable, solubilising or immobilisable derivative thereof; wherein: any one of X 1 , X 2 and X 3 is a N atom and the remaining two of X 1 , X 2 and X 3 are independently CR 13 ; Y is selected from SO 2 and SO; R 1 , R 2 , R 3 , and R 7 and the one or two R 13 groups are each independently selected from R 10 , R 10 is selected from R 8 , alkyl, aryl, heteroaryl and combinations of two or more thereof and combinations with one or more R 9 , or R 10 is one or more moieties R 11 linking one or more alkyl, alkoxy, aryl, heteroaryl or R 8 or R 9 groups or combinations thereof, directly or via a moiety selected from alkylene, arylene, heteroarylene or combinations thereof, wherein alkyl, aryl, heteroaryl groups or moieties thereof may be substituted with one or more groups R 12 , or R 10 is selected from a group R 12 ; R 11 is selected from O—, N—, NH—, N═C, CO—, COO—, CON—, CONH—, SO 2 —, SO 2 N—, SO 2 NH—; R 12 is selected from halogeno, NH 2 , NO 2 , CN, OH, COOH, CONH 2 , C(═NH)NH 2 , SO 3 H, SO 2 NH 2 , SO 2 CH 3 , OCH 3 , OCH 2 CH 3 , CF 3 ; R 8 and R 9 are selected from one or more solubilising moieties independently chosen from i) ionisable organic acids, ii) ionisable organic bases, iii) chemical functions or moieties providing covalent or non-covalent attachment or binding to a solid phase or an immobile receptor and combinations thereof; R 4 , R 5 and R 6 are each independently selected from H and R 10 , or two of R 4 to R 6 are linked to form a cyclic ether or amine containing one or more additional oxygen or nitrogen atoms, and wherein at least one of R 3 , R 5 or R 7 is R 10 .