Patent ID: 7625918

Claim:
A form of hydrocodone bitartrate which is selected from the group consisting of: Form II, Form III, Form IV, Form V, Form VI, Form VII, Form VIII, Form IX, Form X, and an amorphous form; wherein Form II has the following XRPD °2θ peaks and relative intensities (I/Io): °2θ I/Io 10.39 100 10.66 11 14.36 12 16.61 12 16.98 14 17.13 43 18.32 28 20.86 27 21.22 17 21.37 53 23.01 25 24.81 19 27.17 12 28.29 10 30.24 19 33.55 20 Form III has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 4.86 14 6.74 10 8.82 21 9.10 13 9.40 19 10.40 100 13.44 22 14.16 23 14.61 12 16.30 45 16.64 24 16.96 35 17.48 19 18.91 10 19.94 60 20.33 40 21.78 20 22.24 10 22.60 16 23.57 51 23.96 12 24.41 14 25.38 18 26.74 35 27.42 34 27.68 17 29.51 10 30.87 19 31.54 10 36.40 11 Form IV has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 7.54 22 11.21 66 12.09 16 15.24 57 15.66 24 17.87 16 19.21 49 19.98 19 21.74 11 22.80 100 23.54 18 24.58 26 25.02 27 Form V has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 6.57 56 8.96 27 12.16 30 14.54 53 15.16 10 19.88 14 20.76 100 22.62 12 24.04 17 24.82 15 Form VI has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 6.54 12 6.85 51 9.39 40 12.54 36 12.92 62 13.30 37 14.10 28 15.23 48 16.62 78 17.00 24 18.01 100 18.82 15 19.67 23 20.75 43 21.22 24 21.85 92 23.21 17 23.76 16 24.52 27 26.15 48 27.74 14 28.06 30 28.52 10 28.91 30 29.38 13 30.03 11 31.40 33 31.88 12 32.74 10 34.46 10 35.14 29 35.66 20 35.96 11 37.28 13 37.80 10 38.58 22 39.08 11 Form VII has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 6.90 40 9.42 12 9.56 14 13.08 42 15.22 20 20.37 25 20.85 24 21.38 71 21.64 81 21.98 100 27.95 11 28.70 13 35.03 11 Form VIII has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 6.82 16 7.35 100 9.79 56 12.70 49 13.00 64 14.70 57 16.04 39 16.78 11 17.08 12 18.11 37 19.43 14 22.27 33 23.07 49 24.33 10 25.50 78 26.54 34 28.62 13 32.09 17 Form IX has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 5.28 47 8.21 10 12.66 52 13.81 19 15.02 20 16.32 58 17.78 73 18.70 42 19.74 85 22.22 100 23.80 29 24.86 12 26.33 37 28.52 26 29.86 16 31.92 12 33.21 19 34.67 16 38.15 25 39.54 11 Form X has the following XRPD °2θ peaks and relative intensities: °2θ I/Io 8.75 36 9.67 18 10.56 100 11.28 24 13.51 26 14.82 34 15.80 19 16.04 35 16.32 16 17.61 20 18.07 28 19.26 24 20.30 42 20.78 13 21.33 26 21.98 14 22.87 41 24.00 14 24.28 19 26.06 43 26.44 25 26.78 17 27.45 22 27.80 11 28.06 14 28.26 12 30.86 11 38.11 11 and the amorphous form has a single broad peak from 7.28-30.76 XRPD °2θ.