Patent ID: 7332269

Claim:
A kit for the simultaneous detection of HCV antibody and HCV antigen comprising A) a solid phase coated with 1) an HCV core peptide, comprising the amino acid sequence of SEQ ID NO: 19, wherein at least two of the following amino acid segments have one or more amino acids deleted or one or more amino acids altered, i) MSTNPKPQRK (residues 1-10); ii) IVGGVYLL (residues 30-37); iii) RLGVRATR (residues 43-50); and iv) AQPGYPWPLYGNEGCGWAGWLLSPRGSRPSWGPTDPRRRSRNLGKV IDTLTCGF (residues 77-130); 2) HCV non-core protein, and 3) at least one anti-HCV monoclonal antibody that binds to HCV core antigen and does not bind with the HCV core peptide described in A) 1); and B) a labeled anti-HCV monoclonal antibody that binds to HCV core antigen and does not bind to the HCV core peptide described in A) 1) and does not bind to the same epitope as the anti-HCV monoclonal antibody described in A) 3).