Patent ID: 7388004

Claim:
A compound of the formula I, wherein R1, R2, R3, R4, R5, and R6, independently of one another, are chosen from: LAG; (C 1 -C 30 )-alkyl, wherein the (C 1 -C 30 )-alkyl is substituted by q LAG units; (C 1 -C 30 )-alkyl, wherein the (C 1 -C 30 )-alkyl is substituted by q LAG units; and wherein at least one carbon atom of the alkyl radical is replaced by a radical chosen from: —S(O) m — (wherein m=0-2), —O—, —(C═O)—, —(C═S)—, —CH═CH—, —C≡C—, —N((C 1 -C 6 )-alkyl)-, —N(phenyl), —N((C 1 -C 6 )-alkyl-phenyl)-, —N(CO—(CH 2 ) 1-10 —-COOH)— and —NH—; H, F, CI, Br, I, CF 3 , NO 2 , N 3 , CN, COO(C 1 -C 6 )-alkyl, CONH 2 , CONH(C 1 -C 6 )-alkyl, CON[(C 1 -C 6 )-alkyl] 2 , (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, or O—(C 1 -C 6 )-alkyl, wherein the alkyl radical is unsubstituted or at least one hydrogen in the alkyl radical is replaced by fluorine; C(═NH)(NH 2 ), PO 3 H 2 , SO 3 H, SO 2 —NH 2 , SO 2 NH(C 1 -C 6 )-alkyl, SO 2 N[(C 1 -C 6 )-alkyl] 2 , S—(C 1 C 6 )-alkyl, S—(CH 2 ) n -phenyl, SO—(C 1 -C 6 )-alkyl, SO—(CH 2 ) n -phenyl, SO 2 —(C 1 -C 6 )-alkyl, or SO 2 —(CH 2 ) n -phenyl, wherein n=0-6, and wherein the phenyl radical is unsubstituted or substituted one or two times, each substituent chosen independently from: F, Cl, Br, OH, CF 3 , NO 2 , CN, OCF 3 , O—(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, and NH 2 ; and NH 2 , NH—(C 1 -C 6 )-alkyl, N((C 1 -C 6 )-alkyl) 2 , NHCO(C 1 -C 6 )-alkyl, phenyl, or O—(CH 2 ) n -phenyl, wherein n=0-6, and wherein the phenyl ring is unsubstituted or substituted one, two, or three times, each substituent chosen independently from: F, Cl, Br, I, OH, CF 3 , NO 2 , CN, OCF 3 , O—(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, NH 2 , NH(C 1 -C 6 )-alkyl, N((C 1 -C 6 )-alkyl) 2 , SO 2 —CH 3 , COOH, COO—(C 1 -C 6 )-alkyl, and CONH 2 ; wherein (LAG) is —(CH 2 ) 0-10 —SO 3 H; —(CH 2 ) 0-10 —P(O)(OH) 2 , —(CH 2 ) 0-10 —O—P(O)(OH) 2 , or —(CH 2 ) 0-10 —COOH and wherein q is 1-5; and wherein at least one of the radicals R1 to R6 must have the meaning: LAG; or (C 1 -C 30 )-alkyl, wherein the (C 1 -C 30 )-alkyl is substituted by q LAG units; or (C 1 -C 30 )-alkyl, wherein the (C 1 -C 30 )-alkyl is substituted by q LAG units; and wherein at least one carbon atom of the alkyl radical is replaced by a radical chosen from: —S(O) m — (wherein m=0-2), —O—, —(C═O)—, —(C═S)—, —CH═CH—, —C≡C—, —N((C 1 -C 6 )-alkyl)-, —N(phenyl)-, —N((C 1 -C 6 )-alkyl-phenyl)-, —N(CO—(CH 2 ) 1-10 —COOH)— and —NH—, or a pharmaceutically acceptable salt thereof, in any stereoisomeric form, or a mixture of any such compounds in any ratio; with the proviso that the compound is not 2-{[4-(4-{1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenoxy)butyl]methylamino}ethanesulfonic acid, or a compound wherein the radicals R1-R6 have the meaning —O—(CH 2 ) 1-10 —COOH, (C 1 -C 6 )-alkylene-COOH or —COOH.