Patent ID: 7579020

Claim:
A controlled release oral dosage formulation comprising: arginine alpha-ketoglutarate in an amount of 60%; and excipient materials comprising microcrystalline cellulose in an amount of 14%, cellulose acetate phthalate aqueous dispersion in an amount of 15%, polyvinylpyrrolidone in an amount of 3%, ethyl acetate in an amount of 2.5%, hydrous magnesium silicate in an amount of 1%, carboxy methyl ether in an amount of 4% and magnesium stearate in an amount of 0.5%; wherein the formulation is characterized by releasing the arginine alpha- ketoglutarate in a manner so as to maintain a constant therapeutic level of arginine alpha-ketoglutarate in the blood over a period of four hours or more.