Patent ID: 8710189

Claim:
An isolated anti-FGFR3 antagonist antibody, wherein the antibody comprises: (a) a light chain variable region comprising: (i) HVR-L1 comprising the amino acid sequence of SEQ ID NO:48, (ii) HVR-L2 comprising the amino acid sequence of SEQ ID NO:49, and (iii) HVR-L3 comprising the amino acid sequence of SEQ ID NO:50; and (b) a heavy chain variable region comprising: (i) HVR-H1 comprising the amino acid sequence of SEQ ID NO:51, (ii) HVR-H2 comprising the amino acid sequence of SEQ ID NO:52, and (iii) HVR-H3 comprising the amino acid sequence of SEQ ID NO:53, wherein the antibody specifically binds FGFR3.