Patent ID: 6900336

Claim:
A compound comprising Formula I: wherein: A is —CH 2 —CH 2 —, or —CH═CH—; B is absent, aryl, or heteroaryl; Z is —C(O)OR′, —C(O)NR′R″, —C(O)NSO 2 R′, —PR′(O)(OR′), —PO(OR′) 2 , or tetrazol-5-yl; wherein R′ and R″ are independently from each other hydrogen or (C 1 -C 6 )alkyl; m is 1, 2, 3, 4, 5, or 6; R 1 is alkyl, alkenyl, alkynyl, cycloalkylalkyl, heterocyclylalkyl, aryl, arylalkyl or heteroaryl; provided that R 1 is alkyl, alkenyl, alkynyl, cycloalkylalkyl, heterocyclylalkyl, aryl, arylalkyl or heteroaryl, when B is aryl or heteroaryl and R 3 , R 4 , R 5 and R 6 are not simultaneously hydrogen, and R 1 is heterocyclylalkyl, aryl, or heteroaryl when B is absent and R 3 , R 4 , R 5 and R 6 are simultaneously hydrogen; R 2 is hydrogen or (C 1 -C 6 )alkyl, (C 1 -C 6 )alkenyl, or (C 1 -C 6 )alkynyl; R 3 , R 4 , R 5 and R 6 are each independently from each other hydrogen or (C 1 -C 6 ) alkyl; or R 3 and R 4 , R 5 and R 6 or R 3 and R 5 taken together with the atom to which they are attached may form a (C 3 -C 7 ) alkyl ring; or a pharmaceutically acceptable salt or solvate, single isomer or racemic or non-racemic mixture of isomers thereof.