Patent ID: 7981900

Claim:
A compound of the formula (V) or a pharmaceutically acceptable salt, enantiomer, or diastereomer form thereof; wherein X 1 and X 2 are N and X 3 and X 4 are C independently substituted with Y; wherein: R 1 is H, C 1-6 alkyl, C 1-6 alkylNR 5 R 6 , where R 5 and R 6 are each independently H, C 1-4 alkyl, aryl, or hetaryl, or may be joined to form a 3-8 membered ring optionally containing one of O, S or NR 7 ; wherein R 7 is H or C 1-4 alkyl; R 2 is selected from C 1-6 alkylOH, OC 2-6 alkylOH, C 1-6 alkylNR 8 R 9 , OC 2-6 alkylNR 8 R 9 , C 1 - 6 alkylNR 8 COR 9 , OC 2-6 alkylNR 8 COR 9 , C 1 - 6 alkylhetaryl, OC 2-6 alkylhetaryl, OCONR 8 R 9 , NR 8 COOR 9 , NR 10 CONR 8 R 9 , CONR 8 R 9 , and NR 8 COR 12 ; wherein R 8 and R 9 are each independently H, C 1-4 alkyl, C 1-4 hetaryl, or cyclohetalkyl, or may be joined to form a 3-8 membered ring optionally containing one of O, S or NR 14 ; wherein R 12 is C 2-4 alkyl, C 1-4 alkylNR 11 R 13 , hetaryl, or cyclohetalkyl; wherein R 11 and R 13 are each independently H, or C 1-4 alkyl, or may be joined to form a 3-8 membered ring optionally containing one of O, S or NR 14 ; wherein R 14 is H or C 1-4 alkyl; wherein R 10 is H or C 1-4 alkyl; R 3 and R 4 are each independently H, halogen, C 1-4 alkyl, OH, OC 1-4 alkyl, CF 3 , or OCF 3 ; Q is CH; W is C 2-4 alkyl, or C 2-6 alkenyl; where C 2-4 alkyl or C 2-6 alkenyl may be optionally substituted with C 1-4 alkyl, OH, OC 1-4 alkyl or NR 15 R 16 ; R 15 , and R 16 are each independently H or C 1-4 alkyl, or may be joined to form a 3-8 membered ring optionally containing one of O, S or NR 17 ; A is aryl, or hetaryl optionally substituted with 0-2 substituents independently selected from halogen, C 1-4 alkyl, CF 3 , aryl, hetaryl, OCF 3 , OC 1-4 alkyl, OC 2-5 alkylNR 18 R 19 , Oaryl, Ohetaryl, CO 2 R 18 , CONR 18 R 19 , NR 18 R 19 , C 1-4 alkylNR 18 R 19 , NR 18 COR 19 , NR 20 CONR 18 R 19 , and NR 18 SO 2 R 19 ; wherein R 18 and R 19 are each independently H, C 1-4 alkyl, C 1-4 alkyl cyclohetalkyl, aryl, hetaryl, C 1-4 alkyl aryl, or C 1-4 alkyl hetaryl, or may be joined to form a 3-8 membered ring optionally containing one of O, S or NR 21 ; wherein R 21 is H or C 1-4 alkyl; wherein R 20 is H or C 1-4 alkyl; Y is selected from H, C 1-4 alkyl and NR 22 R 23 ; wherein R 22 R 23 are each independently H or C 1-4 alkyl.