Patent ID: 7838261

Claim:
A method for inhibiting chemical crosstalk in enzyme-linked detection reactions, using a microreaction array with an array of reaction chambers for receiving substances which interact with one another, each reaction chamber having a respective volume, comprising: connecting the reaction chambers to one another via a supply volume so as to at permit mass transfer between the reaction chambers; selectively securing different enzyme labels in different reaction chambers such that different reaction chambers have a different enzyme label content; allowing enzyme-linked reactions to proceed differently in the reaction chambers based on the different enzyme label content, the enzyme-linked reactions producing a product; and closing the reaction chambers with a housing top part to inhibit chemical crosstalk, the housing top part disposed across openings in the reaction chambers to reduce the volume of the reaction chambers, and inhibit mass transfer of the product between the reaction chambers and the supply volume, in at least one direction, wherein the reaction chambers are mechanically opened and closed to connect the reaction chambers and inhibit mass transfer between the reaction chambers, respectively, and wherein the reaction chambers are closed off by the housing top part by means of a mechanical ram and opened by removing the housing top part.