Patent ID: 8524667

Claim:
A method of treating gout and gouty arthritis in a patient in need thereof, comprising administering to said patient an effective amount of a human IL-1beta binding antibody comprising an antigen binding site comprising: a) at least one immunoglobulin heavy chain variable domain (V H ) which comprises in sequence hypervariable regions CDR1, CDR2 and CDR3, said CDR1 comprising the amino acid sequence set forth as SEQ ID NO:3, said CDR2 comprising the amino acid sequence set forth as SEQ ID NO:4, and said CDR3 comprising the amino acid sequence set forth as SEQ ID NO:5; and b) at least one immunoglobulin heavy chain variable domain (V L ) which comprises in sequence hypervariable regions CDR1′, CDR2′ and CDR3′, said CDR1′ comprising the amino acid sequence set forth as SEQ ID NO:6, said CDR2′ comprising the amino acid sequence set forth as SEQ ID NO:7, said CDR3′ comprising the amino acid sequence set forth as SEQ ID NO:8, wherein said antibody is parenterally administered at a dose between 0.1-50 mg of said antibody per kg body weight of the patient.