Patent ID: 8808520

Claim:
A vertical slice gel electrophoresis cell for causing charged granules to migrate vertically within an upright slice shaped gel matrix, said electrophoresis cell comprising: (a) an upper buffer chamber for housing a volume of pH buffer solution and an upper electrode said upper buffer chamber having a base-plate, sidewalls and two opposite U-shaped side openings with a U-shaped rubber sealing gasket rimmed along each U-shaped side opening so as to enable a vertical slice gel cassette to join said upper buffer chamber at one of said U-shaped side opening in a water tight manner; (b) a vertical slice gel cassette for said gel matrix to be cast in and said electrophoresis to be performed in it, said vertical slice gel cassette having two spacer-spaced side walls, closed left and right margins, a lower opening, and a U-notched upper opening open to one face of said gel cassette; (c) a tightening mechanism for forcing said vertical slice gel cassette to join said upper buffer chamber at one of said U-shaped side openings; (d) a lower buffer chamber having a base-plate and sidewalls, for housing a volume of pH buffer solution, a lower electrode and the lower opening of said vertical slice gel cassette; and (e) a heat absorbing device for absorbing the Joule-heat during running of said electrophoresis; wherein said tightening mechanism comprises at least one piece of a large diameter screw urging ring to be held to face to one U-shaped side opening of said upper buffer chamber at an interval from said U-shaped side opening, into which interval said vertical slice gel cassette may be installed in, the tightening mechanism configured so it is able to force at least one piece of said vertical slice gel cassette to join said upper buffer chamber tightly, as long as said screw urging ring is turning in a tightening direction.