Patent ID: 8557522

Claim:
A process for detecting or quantifying more than one nucleic acid of interest in a library comprising the steps of: a) providing: (i) an array of fixed or immobilized nucleic acids identical in part or whole to said nucleic acids of interest; (ii) a library of nucleic acid analytes isolated from a biological source, which library of nucleic acid analytes may contain the nucleic acids of interest sought to be detected or quantified, wherein each of said nucleic acids of interest comprise at least one inherent universal detection target (UDT); (iii) a universal detection element (UDE) which generates a signal directly or indirectly; and (iv) polymerizing means for synthesizing nucleic acid copies of said nucleic acid analytes; b) synthesizing one or more first nucleic acid copies which are complementary to all or part of said nucleic acid analytes and synthesizing sequences which are complementary to all or part of said UDT to form a complementary UDT; c) hybridizing said first nucleic acid copies with said array of nucleic acids (i) to form hybrids if said nucleic acids of interest are present; d) contacting said UDEs with said complementary UDTs of said first nucleic acid copies to form a complex bound to said array; and e) detecting or quantifying said more than one nucleic acid of interest by detecting or measuring the amount of signal generated from UDEs bound to said array.