Patent ID: 7064125

Claim:
A method for inhibiting LPAAT-β (lysophosphatidic acid acyltransferase β) comprising contacting LPAAT-β with an effective amount of a compound of the Formula: wherein, R 1 is halo, hydroxy, alkylmercapto, mercapto, alkoxy, aryloxy or —NRR wherein each R group is independently selected from hydrogen, alkyl, substituted alkyl, cycloalkyl, aryl, or the R groups are joined together to form a heterocyclic ring with the N; R 2 , R 3 , R 4 and R 5 , each of which may be same or different, are hydrogen, alkyl, substituted alkyl, alkenyl, alkynyl, aryl or aryl substituted with 1 to 3 substituents selected from hydroxy, alkoxy and halogen; or R 2 and R 3 or R 4 and R 5 , together with the nitrogen to which they are attached, form a piperidine, piperazine, or a morpholine ring; or pharmaceutically acceptable salt thereof; thereby inhibiting LPAAT-β.