Patent ID: 7018537

Claim:
Chiral stationary phase represented by the structure (I): in which: P is: (i): a chiral group in an enantiomerically pure form, chosen between: —(CH 2 ) n NHCOCH(R 1 )NH(R 2 ) where: n ranges from 2 to 4, R 1 is C 1 –C 5 linear or branched alkyl, aryl; R 2 is COAr or Ar, where Ar is an aryl or alkylaryl group, optionally substituted with one or more groups chosen among: NO 2 , CN, Cl, CH 3 , OCH 3 —COCH(R 1 )NH(R 2 ) where: R 1 and R 2 are defined as above; (ii) or P is a spacer group covalently bound to a solid support for chromatography Q is: (i) a chiral group in an enantiomerically pure form, chosen among: —CHR 10 R 11 where: R 10 is H, C 1 –C 5 linear or branched alkyl; R 11 is cycloalkyl, arylalkyl, aryl, optionally substituted with one or more groups chosen among: NO 2 , CN, Cl, CH 3 , OCH 3 —CH(R 13 )CONH(R 14 ) where: R 13 is H, C 1 –C 5 linear or branched alkyl, aryl, optionally substituted with NO 2 , CN, Cl, CH 3 , OCH 3 ; R 14 is alkylaryl, aryl, optionally substituted with one or more groups chosen among: NO 2 , CN, Cl, CH 3 , OCH 3 —CH(R 3 )CH(R 4 )(NHR 5 ) where: R 3 and R 4 independently of each other are C 1 –C 5 linear or branched alkyl, aryl, alkylaryl, optionally substituted with NO 2 , CN, Cl, CH 3 , OCH 3 , or R 3 forms with R 4 and with the carbon atoms bound to R 3 and R 4 a 5–6 term ring; R 5 is an aryl, benzoyl group, optionally substituted with one or more groups chosen among: NO 2 , CN, Cl, CH 3 , OCH 3 . (ii) or Q is a spacer group covalently bound to a solid support for chromatography, and in which the aforesaid formula (I) always contains one chiral group and one spacer group bound to a solid support for chromatography, as defined above.