Patent ID: 7960383

Claim:
A compound of formula (I) wherein R 1 represents: a hydrogen atom; an alkyl, alkenyl or alkynyl group, which is optionally substituted by one or more substituents chosen from halogen atoms and hydroxy, alkoxy, aryloxy, alkylthio, arylthio, oxo, amino, mono-alkylamino, di-alkylamino, acylamino, hydroxycarbonyl, alkoxycarbonyl, carbamoyl, mono-alkylcarbamoyl, and di-alkylcarbamoyl groups; R 2 represents a monocyclic or polycyclic heteroaryl group, which is optionally substituted by one or more substituents chosen from: halogen atoms; alkyl and alkylene groups, which are optionally substituted by one or more substituents chosen from halogen atoms and phenyl, hydroxy, alkoxy, aryloxy, alkylthio, arylthio, oxo, amino, mono-alkylamino, di-alkylamino, acylamino, hydroxycarbonyl, alkoxycarbonyl, carbamoyl, mono-alkylcarbamoyl, and di-alkylcarbamoyl groups; and phenyl, hydroxy, hydroxycarbonyl, hydroxyalkyl, alkoxycarbonyl, alkoxy, cycloalkoxy, nitro, cyano, aryloxy, alkylthio, arylthio, alkylsulfinyl, alkylsulfonyl, alkylsulfamoyl, acyl, amino, mono-alkylamino, di-alkylamino, acylamino, hydroxycarbonyl, alkoxycarbonyl, carbamoyl, mono-alkylcarbamoyl, di-alkylcarbamoyl, ureido, N′-alkylureido, N′, N′-dialkylureido, alkylsulfamido, aminosuphonyl, mono-alkylaminosulfonyl, di-alkylaminosulfonyl, cyano, difluoromethoxy, and trifluoromethoxy groups; R 3 represents a hydrogen atom or an alkylcarbonyl group wherein the alkyl group is optionally substituted by one or more substituents chosen from halogen atoms and phenyl, hydroxy, hydroxyalkyl, alkoxy, aryloxy, alkylthio, arylthio, oxo, amino, mono-alkylamino, di-alkylamino, acylamino, hydroxycarbonyl, alkoxycarbonyl, carbamoyl, mono-alkylcarbamoyl, and di-alkylcarbamoyl groups; and R 4 represents a group of formula: G-L1-(CRR′) n — wherein n is an integer from 0 to 3; R and R′ are each independently chosen from hydrogen atoms or lower alkyl groups; L1 is a linker chosen from a direct bond, or —O—, —CO—, —NR″—, —O(CO)NR″—, —O(CO)O—, —O—(CO)—, —(CO)O—, —NR″—(CO)— or —O(R″O)(PO)O— groups wherein R″ is chosen from hydrogen atoms or lower alkyl groups; G is chosen from hydrogen atoms or alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocyclyl, aryl, arylalkyl or heteroaryl groups, said groups being optionally substituted with one or more substituents chosen from: halogen atoms; alkyl and alkenyl groups, which are optionally substituted by one or more substituents chosen from halogen atoms; and hydroxy, alkoxy, cycloalkyloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylsulfamoyl, amino, mono- or di-alkylamino, acylamino, nitro, acyl, hydroxycarbonyl, alkoxycarbonyl, carbamoyl, mono-alkylcarbamoyl, di-alkylcarbamoyl, ureido, N′-alkylureido, N′,N′-dialkylureido, alkylsulfamido, aminosuphonyl, mono-alkylaminosulfonyl, di-alkylaminosulfonyl, cyano, difluoromethoxy and trifluoromethoxy groups; or pharmaceutically acceptable salts or N-oxides thereof.