Patent ID: 8362084

Claim:
A method for inhibiting a histone deacetylase in a subject, comprising administering to the subject a pharmaceutically acceptable composition comprising a therapeutically effective amount of a compound represented by the general formula A-B-C, or a pharmaceutically acceptable salt thereof, formulated together with one or more pharmaceutically acceptable carriers or diluents, wherein: A is R 1 is an alkyl group substituted by one or more moieties selected from the group consisting of halogen, hydroxyl, carboxylate, alkoxycarbonyl, aryloxycarbonyl, alkylcarbonyl, arylcarbonyl, aldehyde, thiocarbonyl, alkoxyl, unsubstituted amino, monosubstituted amino, disubstituted amino, amido, amidine, imine, nitro, azido, sulfhydryl, alkylthio, cyano, trifluoromethyl, sulfonato, sulfamoyl, sulfonamido, heterocyclyl, aralkyl, aromatic, and heteroaromatic moieties; B is a substituted or unsubstituted C 2 -C 8 alkenylidene; and C is wherein Y is O.