Patent ID: 7166624

Claim:
A compound according to Formula (I): wherein: X is selected from the group consisting of: (CH 2 ) n , NR2, O, NR2CO, CONR2 and a bond; Y is selected from the group consisting of: O, CH 2 and a covalent bond; Z is selected from the group consisting of: hydrogen and fluorine; R is selected from the group consisting of: C 2-6 alkyl optionally substituted by alkoxy, halogen, or C 1-3 alkylsulfanyl; C 2-6 alkenyl optionally substituted by alkoxy, halogen, or C 1-3 alkylsulfanyl; C 2-6 alkynyl optionally substituted by alkoxy, halogen, or C 1-3 alkylsulfanyl; (CH 2 ) n —C 3-6 carbocycle optionally substituted by alkoxy, halogen, or C 1-3 alkylsulfanyl; and (CH 2 ) n —R3; R1 is selected from the group consisting of: hydrogen, C 1-3 substituted alkyl, C 2-3 substituted alkenyl, C 2-3 substituted alkynyl, (CH 2 ) n —C 3-6 substituted carbocycle, aryl, heteroaryl, heterocyclic, and aminocarbonyl; provided that X is (CH 2 ) n when R 1 represents aminocarbonyl; R2 is selected from the group consisting of: hydrogen and C 1-3 substituted alkyl; R3 is selected from the group consisting of: phenyl, furan, benzofuran, thiophene, benzothiophene, tetrahydrofuran, tetrahydropyran, dioxane, 1,4-benzodioxane and benzo[1,3]dioxole, each of which is optionally substituted by one or more substituents each independently selected from: Cl, Br, I, C 1-3 alkyl optionally substituted by one to three F, and C 1-2 alkoxy, optionally substituted by one to three F; and n represents an integer between 0 and 2; or a pharmaceutically acceptable salt or solvate thereof.