Patent ID: 7053114

Claim:
A compound of Formula (I): wherein: R 1 and R 2 are independently selected from the group consisting of hydrogen, halo, alkyl, alkylthio, nitro, trihalomethyl, hydroxy, hydroxyalkyl, alkoxy, cyano, aryl, —C(O)R 7 (where R 7 is selected from the group consisting of alkyl, amino, hydroxy, alkoxy, aryl, aryloxy, and aminoalkylamino), —NR 8 R 9 , —NR 8 C(O)R 9 , —SO 2 R 8 , and —S(O) 2 NR 8 R 9 (where R 8 and R 9 are independently selected from the group consisting of hydrogen, alkyl and aryl); R 3 is selected from the group consisting of hydrogen, alkyl, hydroxyalkyl, aminoalkyl, —C(O)R 7 , where R 7 is as defined above, and aryl; R 4 is selected from the group consisting of hydrogen, alkyl, —C(O)R 7 , where R 7 is as defined above, and aryl; R 5 is 3-amino-2-hydroxypropylaminocarbonyl, N-(2-dimethylaminoethyl)-aminocarbonyl, N-(2-diethylaminoethyl)-N-methylaminocarbonyl, N-(3-dimethylaminopropyl)aminocarbonyl, N-(2-diethylaminoethyl)-aminocarbonyl, N-(3-ethylaminopropyl)aminocarbonyl, N-(3-ethylamino-2-hydroxypropyl)aminocarbonyl, N-(3-diethylamino-propyl)aminocarbonyl, 3-amino-2-hydroxypropylaminocarbonyl, 3-dimethylamino-2-hydroxypropylaminocarbonyl, 3-diethylamino-2-hydroxypropylaminocarbonyl, N-(3-diethylamino-2-hydroxy-propyl)aminocarbonyl, N-(2-diethylaminoethyl)-aminocarbonyl or N-(ethylaminoethyl)aminocarbonyl; R 6 is: (a) —OR 13 wherein R 13 is alkyl, trifluoromethyl, carboxyalkyl, aminoalkyl, phosphonooxyalkyl, sulfooxyalkyl, hydroxyalkyl, alkoxyalkyl, aryl, pyrrole, pyrrolidone, imidazole, thiophene, furan, tetrahydropyranyl and monosaccharides wherein the alkyl chain in carboxyalkyl, aminoalkyl, phosphonooxyalkyl, sulfooxyalkyl, hydroxyalkyl, or alkoxyalkyl is optionally substituted with one or two hydroxy group(s) and further wherein one or two carbon atoms in said alkyl chain are optionally replaced by oxygen, —NR 14 — (where R 14 is hydrogen or alkyl), —S—, or —SO 2 —; or (b) —NR 15 R 16 where are R 15 and R 16 are independently selected from the group consisting of hydrogen, alkyl, carboxyalkyl, alkoxyalkyl, aminoalkyl, phosphonooxyalkyl, sulfooxyalkyl, hydroxyalkyl, pyrrole, pyrrolidone, imidazole, thiophene, furan, tetrahydropyranyl and aryl; wherein the alkyl chain in carboxyalkyl, aminoalkyl, phosphonooxyalkyl, hydroxyalkyl, or alkoxyalkyl is optionally substituted with one or two hydroxy group(s) and further wherein one or two carbon atoms in the alkyl chain are optionally replaced by oxygen, —NR 17 —, where R 17 is hydrogen or alkyl, —S—, or —SO 2 —; or R 15 and R 16 together with the nitrogen atom to which they are attached form a heterocycloamino, wherein the heterocycloamino is pyrrole, pyrrolidone, imidazole, thiophere or furan or a pharmaceutically acceptable salt thereof.