Patent ID: 8661630

Claim:
A method of fabricating an implantable device, comprising: forming a coating on a surface of an implantable device, the coating comprising a semi-crystalline reservoir layer that comprises a bioactive agent and a biodegradable semi-crystalline polymer and an amorphous primer layer that comprises a biodegradable amorphous polymer; wherein the biodegradable amorphous polymer has a miscibility of at least 5% in the biodegradable semi-crystalline polymer; wherein the biodegradable semi-crystalline polymer is a semi-crystalline PLLA-GA-CL terpolymer with a content of L-lactide ranging from about 65 molar % or higher, or a combination of semi-crystalline PLLA-GA-CL terpolymers, each with a content of L-lactide ranging from about 65 molar % or higher; and wherein the biodegradable amorphous polymer is an amorphous PLLA-GA-CL terpolymer with a content of L-lactide of about 65 molar % or below, or a combination of amorphous PLLA-GA-CL terpolymers, each with a content of L-lactide of about 65 molar % or below.