Patent ID: 8119374

Claim:
A method for the microbial production of L-serine, which comprises the following steps: (a) obtaining a recombinant microorganism having at least one serine biosynthesis sequence selected from the group consisting of serA, serB, and serC and an endogenous nucleotide sequence according to SEQ ID NO:1, which encodes L-serine dehydratase, but whose nucleotide from positions 506 until 918 are completely deleted, so that the endogenous nucleotide sequence which encodes the L-serine dehydratase, but which is modified by the deletion does not encode a protein with L-serine dehydratase activity; (b) micro biologically producing L-serine from a carbohydrate by fermentation of the recombinant microorganism obtained according to step (a) in a culture medium; and (c) isolating the L-serine from the culture medium, while avoiding decomposition of the L-serine to pyruvate catalyzed by L-serine dehydratase.