Patent ID: 7465798

Claim:
A compound having the Formula III: or a pharmaceutically acceptable salt thereof, wherein: bond a and bond b are each a single bond; k is 1; Q 1 , Q 2 , Q 3 and Q are each CHR 2 ; L is CO 2 H or an ester thereof; Y is O, (CR 3 R 4 ) p or NR 5 ; n′ is 0 or 1; p is 1 to 3; X is OH, OR 3 , OC 1-6 alkyl, OC(═O)-aryl, OC(═O)C 1-6 alkyl OC(═O)OC 1-6 alkyl, or NR 3 R 3 ; each R 1 , R 3 , R 3 , and R 4 is independently selected from the group consisting of hydrogen, C 1-6 alkyl, C 1-6 perhaloalkyl OC 1-6 alkyl, OC 1-6 perhaloalkyl, halogen, thioalkyl, CN, OH, SH, (CH 2 ) n OSO 3 H, (CH 2 ) n SO 3 H, (CH 2 ) n CO 2 R 6 , OSO 3 R 6 , SO 3 R 6 , PO 3 R 6 R 7 ; each R 12 is independently selected from the group consisting of hydrogen, C 1-6 alkyl, C 1-6 perhaloalkyl, OC 1-6 alkyl, OC 1-6 perhaloalkyl, thioalkyl, OH, (CH 2 ) 1 OSO 3 H, (CH 2 ) 1 SO 3 H, (CH 2 ) 1 CO 2 R 6 ,(CH 2 ) 1 SO 2 NR 8 R 9 , (CH 2 ) 1 C(═O)NR 8 R 9 , NR 8 R 9 , alkenyl, alkynyl, or NHCOR 8 , wherein any of said alkyl, Oalkyl, alkenyl or alkynyl can optionally be substituted with up to three substituents selected from the group consisting of halogen, C 1-6 alkyl, OC 1-6 alkyl and CN; each n is an independently selected integer from 0 to 6; each 1 is an independently selected integer from 1 to 6; and Z is aryl, arylalkyl, heteroaryl or heterocyclo, wherein each of said aryl, arylalkyl, heteroaryl and heterocyclo is optionally substituted.