Patent ID: 6855724

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof wherein: X and Y are selected from CH 2 and NR 4 such that one of X and Y is CH 2 and the other is NR 4 ; R 1 and R 4 are independently R 5 ; COR 5 ; CO 2 R 5 ; CONR 6 R 7 ; SO 2 R 5 ; or (C 1-6 alkylene)phenyl, wherein phenyl is substituted by 0 to 3 atoms or groups selected from C 1-6 alkyl, C 1-6 alkylcarbonyl, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, halogen, CF 3 , OH, CN, NR 6 R 7 , COR 7 , CO 2 R 7 or CONR 6 R 7 ; R 2 is phenyl substituted by 0 to 3 atoms or groups selected from C 1-6 alkyl, C 1-6 alkylcarbonyl, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, halogen, CF 3 , OH, CN, NR 6 R 7 , CO 2 R 7 or CONR 6 R 7 ; R 3 is C 1-4 alkyl substituted by 0 to 3 fluorine atoms; R 5 is C 1-6 alkyl; C 2-6 alkenyl; C 2-6 alkynyl; C 3-7 cycloalkyl; a 5 or 6-membered aromatic heterocycle; or a 4 to 7-membered saturated heterocycle; wherein said alkyl, alkenyl, alkynyl and cycloalkyl are substituted by 0 to 3 atoms or groups selected from oxo, halogen, CF 3 , OR 7 , CN, NR 6 R 7 , COR 7 , CO 2 R 7 or CONR 6 R 7 ; wherein said heterocycles contain one to three heteroatoms selected from N, O or S; and wherein said heterocycles are substituted by 0 to 3 atoms or groups selected from C 1-6 alkyl, C 1-6 alkylcarbonyl, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, halogen, CF 3 , OH, CN, NR 6 R 7 , COR 7 , CO 2 R 7 or CONR 6 R 7 ; R 6 is H; C 1-6 alkyl; C 2-6 alkenyl ; C 2-6 alkynyl; C 3-7 cycloalkyl; a 5 or 6-membered aromatic heterocycle; or a 4 to 7-membered saturated heterocycle; wherein said alkyl, alkenyl, alkynyl and cycloalkyl are substituted by 0 to 3 atoms or groups selected from oxo, halogen, CF 3 , OR 7 , CN, COR 7 or CO 2 R 7 ; wherein said heterocycles contain one to three heteroatoms selected from N, O or S; and wherein said heterocycles are substituted by 0 to 3 atoms or groups selected from C 1-6 alkyl, C 1-6 alkylcarbonyl, C 1-6 alkoxy, C 1-6 alkoxycarbonyl, halogen, CF 3 , OH, CN, COR 7 or CO 2 R 7 ; R 7 is H or C 1-6 alkyl; or, when R 6 and R 7 are both attached to the same N atom, NR 5 R 7 may also represent a 5 to 7 membered, saturated, partially unsaturated or aromatic, heterocycle containing from 0 to 2 additional heteroatoms selected from O, N or S.