Patent ID: 6838457

Claim:
A fused heteroaryl compound of formula (Ib): or a salt thereof, wherein: B is a pyrazine or thiophene ring; R 2 and R 3 are combined together with the N atom adjacent thereto to form morpholino; R 4b is -an aryl which has one to five substituents selected from Group A 4 ; Group A 4 is selected from the group consisting of -a lower alkylene-OR, —CONRR′, —NR—CO-Cyc 1 , —NR—SO 2 -Cyc 1 , —OR, —NRR′, —O-a lower alkylene-NRR′ and —O-a lower alkylene-(a nitrogen-containing saturated ring which may have one to five substituents selected from Group A), wherein Cyc 1 is -an aryl which may have one to five substituents selected from Group A, -a heteroaryl which may have one to five substituents selected from Group A, or -a nitrogen-containing saturated heterocyclic group which may have one to five substituents selected from Group A; wherein Group A is selected from the group consisting of -a lower alkyl, -a lower alkenyl, -a lower alkynyl, -a halogen, -a halogenated lower alkyl, -a lower alkylene-OR, —NO 2 , —CN, ═O, —OR, —O-a halogenated lower alkyl, —O-a lower alkylene-NRR′, —O-lower alkylene-OR, —O-a lower alkylene-an aryl, —SR, —SO 2 -a lower alkyl, —SO-a lower alkyl, —COOR, —COO-a lower alkylene-an aryl, —COR, —CO-an aryl, -an aryl, —CONRR′, —SO 2 NRR′, —NRR′, —NR″-a lower alkylene-NRR′, —NR′-a lower alkylene-OR, —NR-a lower alkylene-an aryl, —NRCO-a lower alkyl, —NRSO 2 -a lower alkyl, -a cycloalkyl and -a cycloalkenyl; and wherein R, R′ and R″, which may be the same or different, represent H or a lower alkyl.