Patent ID: 7459141

Claim:
A method of preparing a 99m Tc-labeled organic germanium nanocolloid, comprising the steps of: (i) preparing an organic germanium colloidal solution by dispersing an organic germanium compound in an aqueous solvent; (ii) preparing a solution containing sodium pertechnetate and stannous chloride by dissolving sodium pertechnetate and stannous chloride in an acidic solvent; and (iii) adding the solution containing sodium pertechnetate and stannous chloride drop wise to the organic germanium colloidal solution to form a 99m Tc-labeled organic germanium nanocolloid, wherein the 99m Tc-labeled organic germanium nanocolloid has Chemcial Formula 1: wherein L is selected from the group consisting of bis-carboxyethylgermanium sesquioxide, spirogermanium and lactate-citrate-germanate.