Patent ID: 7153946

Claim:
A compound having the formula: wherein (a) R 1 is selected from: (1) a de-hydroxyl moiety of (i) a hydroxyl-bearing biologically active molecule and analogs and derivatives thereof of formula R 1 —OH, and (2) a de-amino moiety of (i) an amino-bearing biologically active molecule and analogs and derivatives thereof of formula R 1 —NH 2 or a salt or secondary amine thereof; (b) where Z is —O— when R 1 is said de-hydroxyl moiety and Z is —NH— when R 1 is said de-amino moiety; (c) R 2 is selected from —CH(OH)CH(OH)W, and —C(O)H; (d) W is selected from: (1) H, (2) a straight or branched alkyl having 1 to 20 carbons optionally substituted with one or more phenyl, (3) a cycloalkyl optionally substituted with one or more alkyl or phenyl, and (4) an aromatic group optionally substituted with one or more alkyl or electron-withdrawing or electron-donating groups; and (e) Y is selected from: (1) a straight or branched alkyl having 1 to 20 carbons optionally substituted with one or more phenyl, (2) a cycloalkyl optionally substituted with one or more alkyl or phenyl, and (3) an aromatic group optionally substituted with one or more alkyl or electron-withdrawing or electron-donating groups.