Patent ID: 6852718

Claim:
A compound of formula I, or a pharmaceutically acceptable salt thereof: wherein: Z is selected from the group consisting of halogen, hydrogen cyano, nitro, trifluoromethyl, trifluoromethoxy, —OR a , —SR a , —SOR a , —SO 2 R a , —SO 2 NR a R b , —NR a R b , —NR a COR b , —NR a CO 2 R b , —COR a , —CO 2 R a and —CONR a R b ; or R a and R b are independently selected from hydrogen and C 1-6 alkyl; or R a and R b , when linked through a nitrogen atom, together represent the residue of an azetidine, pyrrolidine, piperidine or morpholine ring; E represents a chemical bond or a straight or branched alkylene chain having from 1 to 4 carbon atoms, optionally incorporating an oxygen atom to form an ether linkage; R 1 represents an aryl(C 2-4 )alkyl group, which is unsubstituted or substituted with a substituent selected from: halogen, nitro, trifluoromethyl, trifluoromethoxy, C 1-6 alkyl, keto, hydroxy, C 1-6 alkoxy, C 1-6 alkylthio, and di(C 1-6 )alkylamino; and R 2 represents hydrogen or halogen; with the proviso that the compound is other than 1-[[4-(methylamino)phenyl]-sulfonyl]-4-[2-phenylethyl]piperazine.