Patent ID: 8101714

Claim:
An isolated antimicrobial non-scavenger Receptor A, non-toll like receptor polypeptide optionally having a molecular weight of about 22 kD to about 30 kD and having properties selected from the group consisting of (a) comprising an amino acid sequence selected from the group consisting of (i) (amino acid residues 1-60 of SEQ ID NO: 3); MSAQAEETAPEAAAPVQPSQPAAKKKGPASKAKPASAEKKNKKKKGKGPG KYSQLVINAI (ii) (amino acid residues 1-118 of SEQ ID NO: 3); MSAQAEETAPEAAAPVQPSQPAAKKKGPASKAKPASAEKKNKKKKGKGPG KYSQLVINAIQTLGERNGSSLFKIYNEAKKVNWFDQQHGRVYLRYSIPAL LQNDTLVQVKGLGANGSF (iii) (amino acid residues 27-51 of SEQ ID NO: 3); GPASKAKPASAEKKNKKKKGKGPGKY (iv) (amino acid residues 136-159 of SEQ ID NO: 3) PRKTAKPTKKPAKKAAKKKKRVSG and (v) (amino acid residues 173-203 of SEQ ID NO: 3); PKKADKSPAVSAKKASKPKKAKQTKKTAKKT (b) being a polypeptide depicted in SEQ ID NO:3; (f) being a polypeptide depicted in SEQ ID NO:3 with conservative amino acid substitutions and (g) being a fragment of (a)-(f), wherein said fragment comprises at least 24 contiguous amino acids and antimicrobial activity.