Patent ID: 8227576

Claim:
An isolated therapeutic antibody which is an antibody or antigen binding fragment which binds β-amyloid peptide and which comprises the following CDRs: CDRH1: DNGMA (SEQ ID No:1) CDRH2: FISNLAYSIDYADTVTG (SEQ ID No:2) CDRH3: GTWFAY (SEQ ID No:3) within a human heavy chain variable region originating from the VH3 gene family and: CDRL1: RVSQSLLHSNGYTYLH (SEQ ID No:4) CDRL2: KVSNRFS (SEQ ID No:5) CDRL3: SQTRHVPYT (SEQ ID No:6) within a human light chain variable region originating from the amino acid sequence disclosed in GenPept entry CAA51135 (SEQ ID No:24).