Patent ID: 6867224

Claim:
A compound having formula 1: or a pharmaceutically acceptable salt thereof, wherein: V 1 is a saturated or unsaturated, substituted or unsubstituted hydrocarbon chain or hydrocarbon-heteroatom chain having from 3 to 6 atoms wherein the carbon atom of position 1 is connected to the carbon atom of position 2 to form a five to six member ring wherein the is attached to a substitutionally available position of said ring where the ring is selected from the group consisting of furan, pyran, and thiopyran, and; X 0 is O or S; X 1 is S 1 X 2 is absent; Ar 1 is substituted or unsubstituted aryl; R 1 , R 2 , and R 3 are independently hydrogen, lower alkyl, lower alkoxy, lower thioalkoxy, —O(CH 2 ) p CF 3 , halogen, nitro, cyano, —OH, —SH, —CF 3 , S(O) p Alkyl, S(O) p Aryl, —(CH 2 ) m OR 4 , or —(CH 2 ) m NR 5 R 6 , COR 4 , —CO 2 H, —CO 2 R 4 , or R 4 is hydrogen, alkyl, alkenyl, alkynyl, or aryl; R 5 and R 6 are independently hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, SO 2 Alkyl or, SO 2 Aryl; m is 0 to 5; n is 0 to 5; and p is 0 to 2.