Patent ID: 6929779

Claim:
A detection system for a bio-separation device, comprising: a separation channel having an exit and a first width; a detection section having a second width larger than the first width of the separation channel, wherein flow from the separation channel exits from the exit of the separation channel into the detection section, and wherein mixing or diffusion of analytes occurs near the exit of the separation channel; the separation channel having a first width, and the detection section having a second width larger than the first width of the separation channel and a transition in width from the first width of the separation channel to the second width of the detection section; an excitation system introducing excitation radiation at the detection section; and a detector system detecting radiation emission axially from a location along the detection section defining a detection zone as analytes pass the detection zone, said location being defined at a distance of 100 to 500 times the second width of the detection section from the exit of the separation channel, thereby allowing analytes sufficient distance to regroup from the mixing or diffusion near the exit of the separation channel, said detector system including an optic fiber having an end in close proximity to the detection zone.