Patent ID: 7618436

Claim:
A tissue puncture closure device for partial insertion into and sealing of an internal tissue wall puncture, comprising: a filament extending from a first end of the closure device to a second end of the closure device; an anchor for insertion through the tissue wall puncture attached to the filament at the second end of the closure device; a sealing plug slidingly attached to the filament adjacent to the anchor, the sealing plug configured to be compressed in an axial direction toward the anchor; a handle at the first end of the closure device, the handle comprising: a tamping assembly comprising a tamping device connected to a variable gear ratio transmission, wherein a first gear ratio of the variable gear ratio transmission is defined by engagement of a first portion of a first gear and a first portion of a second gear and is changeable to a second gear ratio defined by engagement of a second portion of the first gear with a second portion of the second gear when the sealing plug passes through an outlet of a carrier tube of the closure device, the second gear ratio providing distal advancement of the tamping device to compress the sealing plug in the axial direction.