Patent ID: 8101706

Claim:
A target molecule-POZ conjugate comprising at least one target molecule linked to a heterofunctional polyoxazoline derivative of the general structure: R 1 —{[N(COX)CH 2 CH 2 ] o —[N(COR 2 )CH 2 —CH 2 )] n } a —S-U-W wherein: R 1 is an initiating group; R 2 is an unsubstituted or substituted alkyl, an unsubstituted or substituted alkenyl, an unsubstituted or substituted aralkyl or an unsubstituted or substituted heterocyclylalkyl group; U is a linking group; X is a pendent moiety containing a first functional group; W comprises a moiety bearing a second functional group; a is random which indicates a random copolymer or block which indicates a block copolymer; o is an integer selected from 1-50; n is an integer selected from 0-1000; and wherein the first and second functional groups are chemically orthogonal to one another; and wherein the at least one target molecule is linked to the polyoxazoline derivative through at least one of the first or second functional groups.