Patent ID: 8350048

Claim:
A compound of the formula the salts and stereoisomeric forms thereof, wherein R is H, phenyl, pyridyl, C 1-6 alkyl or wherein A and B are independently from each other H; C 1-6 alkyl optionally substituted with alkynyl, heteroaryl or a heteroatom selected from nitrogen, oxygen or sulfur which is optionally substituted with C 1-6 alkyl; or wherein A and B together with the nitrogen to which they are attached form a 5 or 6 membered saturated, partially or completely unsaturated heterocyclic ring containing 1 to 4 hetero atoms each independently selected from nitrogen, oxygen or sulfur, said heteroatoms are optionally substituted with C 1-6 alkyl; R 1 is selected from the group comprising R 2 is C 1-6 alkyl optionally substituted with OH, aminoalkyl, pyrrolidinyl, morpholinyl, alkynyl or C 3-7 cycloalkyl optionally substituted with halogen; R 3 is OH; R 4 is H or alkyl; R 5 is pyridyl or phenyl optionally substituted with halogen; X is O, S or N optionally substituted with C 1-6 alkyl.