Patent ID: 7354944

Claim:
A compound of Formula I wherein: Y is â€”N(R 4 )R 5 or â€”OR 5 ; X is â€”N(R 6 ); R 1 is a heteroaryl; R 2 is H; R 3 is selected from the group consisting of â€”(CR 7 R 8 ) t (aryl) and â€”(CR 7 R 8 ) t (heteroaryl); R 4 is â€”H, C 1 -C 8 alkyl, â€”C(O)(CR 7 R 8 ) t )N(R 6 ) 2 , â€”C(O)(CR 7 R 8 ) t , â€”C(O) 2 (CR 7 R 8 ) t , â€”(CR 7 R 8 ) t (aryl), â€”(CR 7 R 8 ) t (heteroaryl), â€”(CR 7 R 8 ) t (cycloalkyl), or â€”(CR 7 R 8 ) t (heterocyclyl); R 5 and R 6 are â€”H; and R 7 and R 8 are independently selected from â€”H, C 1 -C 6 alkyl, and aryl; wherein n is 1; m is 1; and each t is independently an integer from 1 to 3; wherein each of the above alkyl, aryl, heteroaryl, cycloalkyl, and heterocyclyl moieties are optionally and independently substituted by 1-3 substituents selected from amino, aryl, heteroaryl, cycloalkyl, or heterocyclyl optionally substituted by 1-5 substituents selected from C 1 -C 6 alkoxy, C 1 -C 6 alkyl optionally substituted by halo, aryl, halo, heteroaryl, C 1 -C 6 hydroxyl, and â€”NHS(O) 2 â€”(C 1 -C 6 alkyl); C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 hydroxyalkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkylamino, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl, wherein each of which may be interrupted by one or more hetero atoms, cyano, halo, hydroxy, nitro, or â€”O-aryl; or a pharmaceutically acceptable salt, hydrate, or stereoisomer thereof.