Patent ID: 8207379

Claim:
A method for producing an optically active aminoalcohol compound, said method comprising performing a hydrogenation, in presence of a ruthenium compound represented by a formula (I): [Chemical formula 1] Ru(X) 2 (P xx )[R 1 R 2 C(NH 2 )—R 3 R 4 C(NH 2 )] (I) wherein X represents a halogen atom, Pxx represents an optically active bidentate phosphine ligand represented by a formula (II): [Chemical formula 2] P(R 5 ) 2 -A-P(R 5 ) 2 (II) wherein R 5 represents a phenyl group that has substituents, represented by a formula (III): wherein R a represents a hydrogen atom, halogen atom, C1 to C6 alkyl group, C1 to C6 alkoxy group or C6 to C18 aryl group, and R b represents a halogen atom, C1 to C6 alkyl group, C1 to C6 alkoxy group or C6 to C18 aryl group, and A represents a divalent organic group, and R 1 R 2 C(NH 2 )—R 3 R 4 C(NH 2 ) represents an optically active diamine ligand, in which each of R 1 to R 4 independently represents a hydrogen atom, unsubstituted or substituted C1 to C20 alkyl group, unsubstituted or substituted C2 to C20 alkenyl group, unsubstituted or substituted C3 to C8 cycloalkyl group, unsubstituted or substituted C4 to C8 cycloalkenyl group, unsubstituted or substituted C6 to C18 aryl group, or unsubstituted or substituted C7 to C18 aralkyl group, and either of R 1 and R 2 may be bonded to either of R 3 and R 4 to form a ring, of an α-aminoketone compound represented by a formula (IV): wherein each of R 10 and R 11 independently represents an unsubstituted or substituted C1 to C6 alkyl group, or unsubstituted or substituted C6 to C18 aryl group, each of R 12 and R 13 represents a hydrogen atom, unsubstituted or substituted C1 to C6 alkyl group, unsubstituted or substituted C6 to C18 aryl group, R 14 CO— group or R 14 OCO— group, R 14 represents an unsubstituted or substituted C1 to C6 alkyl group, or unsubstituted or substituted C6 to C18 aryl group, and R 10 and R 11 , and R 12 and R 13 , may be respectively bonded together to form a ring.