Patent ID: 8518989

Claim:
A method for treating a disease condition characterized by upregulation of transporter ATB 0,+ selected from the group consisting of colon cancer, inflammatory bowel disease, ulcerative colitis, Crohn's disease, lung cancer, cervical cancer, and cancers resulting from metastases from primary colon cancer sites in a patient, the method comprising: administering an effective amount of a prodrug or pharmaceutically acceptable salts of said prodrug to said patient, wherein said prodrug comprises an amino acid capable of intracellular transport by ATB 0,+ attached to a short-chain fatty acid; wherein said amino acid capable of intracellular transport by ATB 0,+ is attached to said short-chain fatty chain acid by a hydroxyl group of the amino acid to form an ester with the amino acid, or said amino acid capable of intracellular transport by ATB 0,+ is attached said short-chain fatty chain acid by the amino group of the amino acid to form an amide with the amino acid.