Patent ID: 7175861

Claim:
An anti-depression pharmaceutical composition comprising a therapeutically effective amount of an active ingredient, in admixture with a pharmaceutically acceptable carrier or diluent for the active ingredient, in which the active ingredient is an organic eluate prepared by a method comprising the following steps i) to iii) or a filtrate prepared by a method comprising the following steps i) to iv): i) extracting Polygala with a polar solvent, the polar solvent being water or a mixture of water and methanol or ethanol; ii) extracting the polar solvent extract with an organic solvent, and obtaining an aqueous fraction from said extraction; iii) introducing the polar solvent extract or the aqueous fraction into a reverse phase chromatography column, eluting the column with water and an organic solvent, and collecting an organic eluate; and iv) filtrating said organic eluate with a molecular sieve to obtain a filtrate having a molecular mass less than 30000 Dalton in the organic eluate.