Patent ID: 7129208

Claim:
An amphiphile for the formation of a synthetic ion channel in a phospholipid bilayer membrane, the amphiphile corresponding to the formula A-C-H 1 -B-H 2 -T wherein A is hydrocarbyl or —NR 1 R 2 linked to the connector, C, optionally through a nitrogen, oxygen or sulfur atom; each of R 1 and R 2 are independently hydrocarbyl or substituted hydrocarbyl; C is a single covalent bond or a hydrocarbyl, substituted hydrocarbyl or heterocyclo; H 1 is substituted hydrocarbyl, heterocyclo, or peptide, provided that H 1 contains at least one glycine residue; B is substituted hydrocarbyl, carbocyclic, or heterocyclo; H 2 is substituted hydrocarbyl, heterocyclo, or peptide, provided that H 2 contains at least one glycine residue; and T is hydrocarbyl, substituted hydrocarbyl or heterocyclo.