Patent ID: 8883841

Claim:
A method of inhibiting activity of a Ras protein comprising contacting a cell expressing elevated levels of Ras protein or expressing a mutant Ras protein with a compound, or a salt thereof, in an amount sufficient to inhibit the activity of the mutant Ras protein, wherein the compound has a formula: wherein: R 1 is halo, hydrogen, carboxymethyl, carboxyethyl, carboxypropyl, or carboxybutyl; R 2 is methanol, —C(O)H, —OC(O)CH 3 , or amino; R 3 is halo or hydrogen; R 4 is halo or hydrogen; R 5 is halo or hydrogen; R 6 is halo or hydrogen; R 7 is halo or hydrogen; R 8 is halo, hydrogen, —CF 3 , —NO 2 , or —CH 3 ; R 9 is halo, hydrogen, —CF 3 , —NO 2 , or —CH 3 ; R 10 is halo, hydrogen, —CF 3 , —NO 2 , or —CH 3 ; and R 11 is halo, hydrogen, —CF 3 , —NO 2 , or —CH 3 .