Patent ID: 8729031

Claim:
A compound of formula (IV): wherein: X1 and X2 are Leu and Val, respectively or Val and Ile, respectively; R 3 is H or C 1-6 alkyl; L is a straight or branched C 0-15 alkyl chain wherein optionally one or more carbons are replaced by a heteroatom independently selected from the group consisting of N, O and S, wherein said chain is optionally substituted by one or more oxo or nitro groups with the proviso that a heteroatom is not bonded directly to the N of the group —NR 3 ; Ar 1 is phenyl substituted by one or two NO 2 groups, one to five halogen groups, one or two C 1-3 haloalkyl groups or a combination thereof; Z is selected from the group consisting of H, C 1-6 alkyl and an amino acid residue; and p is 0 or 1, or a pharmaceutically acceptable salt thereof.