Patent ID: 7309699

Claim:
A compound of the formula (I): or a pharmaceutically acceptable salt, thereof, wherein: A is N or N + —O − n is 0, 1, or 2; Y is selected from the group consisting of O, S, and —N(R 1 )—; Ar 1 is a group of the formula: Ar 2 is a group of the formula: X 1 , X 2 , x 3 , and X 4 are each independently selected from the group consisting of N and —C(R 2 ); one of X 5 , X 6 , X 7 , X 8 and X 9 is —C and the others are each independently selected from the group consisting of N and —C(R 5 ), and group (b) is attached to Ar 1 through one of X 5 , X 6 , X 7 , X 8 and X 9 that is represented by C; one of H 10 , X 11 , X 12 , and X 13 is C and the others are each independently selected from the group consisting of N, —N(R 1 ), O, S and —C(R 5 ) and group (c) is attached to Ar 1 through one of X 10 , X 11 , X 12 , and X 13 that is represented by C; R 1 is hydrogen or alkyl; R 2 at each occurrence is independently selected from the group consisting of hydrogen, halogen, alkyl, —OR 3 , and —NHR 4 ; R 2a is halogen or alkyl; R 3 and R 4 are each independently selected from the group consisting of hydrogen, alkyl, alkylcarbonyl, and arylcarbonyl; R 5 is selected from the group consisting of hydrogen, halogen, nitro, alkyl, aryl, alkylcarbonyl, arylcarbonyl, —OR 6 and —NR 8 R 9 ; R 6 is independently selected from the group consisting of hydrogen, alkyl, alkylcarbonyl, and arylcarbonyl; and R 8 and R 9 are each independently selected from the group consisting of hydrogen, alkyl, aryl, arylalkyl, cycloalkylalkyl, alkylcarbonyl, —N═C(alkyl)(alkoxycarbonyl), alkoxycarbonyl, arylcarbonyl, aryloxycarbonyl, and alkylsulfonyl.