Patent ID: 7670607

Claim:
A composition consisting of a recombinant virus into the genome of which is inserted DNA sequences coding for (i) the early E6 polypeptide of a papillomavirus; (ii) the early E7 polypeptide of a papillomavirus; (iii) the late L1 polypeptide of a papillomavirus; (iv) the late L2 polypeptide of a papillomavirus; and (v) a polypeptide having an immunostimulatory activity; wherein each of said DNA sequences is placed under the control of the independent elements necessary for its expression in a host cell or organism; wherein said polypeptide having an immunostimulatory activity is selected from the group consisting of interleukin-2, interleukin-7, and the co-adhesion molecule B7.2; wherein said recombinant virus is provided in combination with a pharmaceutically acceptable carrier; and wherein said recombinant virus is a vaccinia virus selected from the group consisting of a Vaccinia virus Copenhagen, a Vaccinia virus Wyeth, and a Modified Vaccinia Ankara virus.