Patent ID: 8017349

Claim:
A method for detecting a Neuronal Attachment Factor-1 (NAF-1) polypeptide comprising: (a) obtaining a biological sample from a host; (b) contacting the biological sample with an antibody or fragment thereof that specifically binds to a protein selected from the group consisting of: (i) a protein whose amino acid sequence consists of amino acid residues 1 to 331 of SEQ ID NO:2; (ii) a protein whose amino acid sequence consists of amino acid residues 2 to 331 of SEQ ID NO:2; (iii) a protein whose amino acid sequence consists of amino acid residues 24 to 331 of SEQ ID NO:2; (iv) a protein whose amino acid sequence consists of amino acid residues 27 to 331 of SEQ ID NO:2; (v) a protein whose amino acid sequence consists of amino acid residues 284 to 330 of SEQ ID NO:2; (vi) a protein whose amino acid sequence consists of amino acid residues 75 to 100 of SEQ ID NO:2; (vii) a protein whose amino acid sequence consists of amino acid residues 168 to 180 of SEQ ID NO:2; (viii) a protein whose amino acid sequence consists of amino acid residues 204 to 226 of SEQ ID NO:2; (ix) a protein whose amino acid sequence consists of amino acid residues 258 to 281 of SEQ ID NO:2; (x) a protein whose amino acid sequence consists of amino acid residues 291 to 327 of SEQ ID NO:2; (xi) a protein whose amino acid sequence consists of the amino acid sequence of the full-length polypeptide encoded by the cDNA contained in ATCC Deposit No. 97343; (xii) a protein whose amino acid sequence consists of the mature form of NAF-1 encoded by the cDNA contained in ATCC Deposit No. 97343; and (xiii) a NAF-1 protein purified from a cell culture, wherein said NAF-1 protein is encoded by a polynucleotide encoding amino acids 1 to 331 of SEQ ID NO:2; (c) allowing said antibody or fragment thereof to bind said NAF-1 polypeptide; and (d) detecting said bound antibody.