Patent ID: 7718414

Claim:
A transformed microorganism that belongs to the Enterobacteriacae genus, the microorganism comprising: a polynucleotide encoding a polypeptide having S-adenosylmethionine-6-N-lysine methyltransferase activity from Neurospora crassa , wherein the polynucleotide is a polynucleotide encoding the amino acid sequence of SEQ ID NO: 11; a polynucleotide encoding a polypeptide having 6-N-trimethyllysine hydroxylase activity wherein the polynucleotide is a polynucleotide encoding the amino acid sequence of SEQ ID NO: 12; a polynucleotide encoding a polypeptide having 3-hydroxy-6-N-trimethyllysine aldolase activity wherein the polynucleotide is a polynucleotide encoding the amino acid sequence of SEQ ID NO: 13; a polynucleotide encoding a polypeptide having γ-trimethylaminoaldehyde dehydrogenase activity wherein the polynucleotide is a polynucleotide encoding the amino acid sequence of SEQ ID NO: 14, and a polynucleotide encoding a polypeptide having γ-butyrobetaine hydroxylase activity wherein the polynucleotide is a polynucleotide encoding the amino acid sequence of SEQ ID NO: 15.