Patent ID: 7229984

Claim:
A compound of the formula I: or a pharmaceutically accentable salt thereof, wherein A is C(═O) or CH 2 ; X is O—, S(O) q —, or —NR 8 —; Y is —N— or —CH—; Z is —(CR 6 R 7 ) r —, or —S(O) t —; Ar is phenyl optionally substituted with halo, alkyl, haloalkyl, heteroalkyl, alkoxy, cyano, —S(O) q —R c , —C(═O)—NR c R d , —SO 2 —NR c R d , —N(R c )—C(═O)—R d , or —C(═O)—R c ; or heteroaryl selected from pyridin-3-yl, 2-chlorothien-5-yl and indolyl-3-yl; each R 1 is independently hydrogen or alkyl; each of R 2 , R 6 , R 7 and R 8 is independently hydrogen or alkyl; each of R 3 and R 4 is independently halo, alkyl, haloalkyl, alkoxy, cyano, —S(O) s —R c , —C(═O)—NR c R d , —SO 2 —NR c R d , —N(R c )—C(═O)—R d , or —C(═O)—R c ; each of R c and R d is independently hydrogen or alkyl; each of m and n is independently an integer from 0 to 3; r is an integer from 1 to 3; and each of k, q, s, and t is independently an integer from 0 to 2.