Patent ID: 7083915

Claim:
A method of detecting the absence of a mutation in the sequence of polycystic kidney disease type 2 (PKD2) gene in a human subject, comprising the steps of: (a) obtaining a polynucleotide sample containing the sequence of PKD2 gene from a human subject; (b) comparing the polynucleotide sample to a reference human wild-type PKD2 sequence comprising SEQ ID NO:6; and (c) determining the differences, if any, between the sequence of PKD2 gene in the polynucleotide sample and the reference wild-type PKD2 sequence comprising SEQ ID NO:6, wherein an absence of differences between the sequence of PKD2 gene in the polynucleotide sample and the reference wild-type PKD2 sequence comprising SEQ ID NO:6 is indicative of the absence of a mutation in the sequence of PKD2 gene in a human subject.