Patent ID: 7230021

Claim:
A compound of the formula: and its pharmaceutically accepted salts, wherein A—B is ethane, (E) and (Z)-ethene, (E) and (Z)-substituted ethene, ethyne, K is hydrogen or one-to-three carbon alkyl group, Q═NH or O, X is hydrogen, hydroxy, alkoxy, alkyl, aminocarbonyl, amino, alkylamino, dialkylamino, alkoxycarbonylamino, Y is S, NH, or O, Z is hydrogen, hydroxy, aminocarbonyl, alkylamino, dialkylamino, alkoxycarbonylamino, but not t-butoxycarbonylamino when R 4 is dimethylamino, R 1 is hydrogen or one-to-three carbon alkyl group, and R is selected from the following: (a) Alkene of the formula: wherein R 2 is optionally substituted with one or more substituents selected from alkyl, alkylhydroxy, alkylalkoxy, alkylamino, alkylaminoalkyl, or alkylaminodialkyl; (b) Alkenylaryl of the formula: wherein R 3 is optionally substituted with one or more substituents selected from hydrogen, alkyl, alkenyl, alkynyl, hydroxy, alkoxy, amino, alkylamino, dialkylamino, trifluoromethane, or fluoro; and (c) Methyldienylpentyl of the formula: wherein R 4 is optionally substituted with one or more substituents selected from hydrogen, alkyl, alkenyl, alkynyl, hydroxy, alkoxy, amino, alkylamino, or dialkylamino; and (d) Methylalkenylpentyl of the formula: wherein R 4 is optionally substituted with one or more substituents selected from hydrogen, alkyl, alkenyl, alkynyl, hydroxy, alkoxy, amino, alkylamino, or dialkylamino.