Patent ID: 7632666

Claim:
A method of production of optically active halohydrocarbons and alcohols using hydrolytic dehalogenation catalysed by a haloalkane dehalogenase wherein haloalkane dehalogenase DbjA having the amino acid sequence SEQ ID NO: 2 is applied to at least one racemic or prochiral chlorinated, brominated or iodinated compound at a temperature range between +10 and +70° C. and pH value between 4.0 and 12.0, in an aqueous system or in a monophasic organic solution or in a monophasic organic/aqueous solution or in organic/aqueous biphasic systems, wherein the chlorinated, brominated or iodinated compounds have at least one halogen atom bound directly to the chiral or prochiral carbon and the nucleophilic attack takes place directly on the chiral or prochiral carbon.