Patent ID: 8497302

Claim:
A method of preparing molecules corresponding to formula (I) below: in which: A represents a group selected from —CH═CH— and —CH 2 —CH 2 —, x 1 is an integer selected from 0 and 1, x 2 is an integer selected from 0 and 1, R 1 , R 2 , independently of one another, represent a group selected from: H, C 1 -C 6 alkyls, phenyl, benzyl, and —CO—R 4 , and R 4 represents a group selected from: C 1 -C 6 alkyls, phenyl, and benzyl, R 3 represents a group selected from: H, C 1 -C 6 alkyls, phenyl, benzyl, and a peptide chain of amino acids comprising 1 to 30 amino acids, * represents the optical configuration L or D of the amino acid —NH—CHR—COO—, * can represent one or other of the configurations depending on the choice of R, R represents an amino acid side chain selected from: —H (glycine), —CH 3 (L-alanine, D-alanine), —CH 2 OH (L-serine), —CHOH—CH 3 (L-threonine), —CH 2 OR 5 (L-serine protected on its hydroxyl function), and —CHOR 5 —CH 3 (L-threonine protected on its hydroxyl function), R 5 represents a group selected from: H, C 1 -C 6 alkyls, phenyl, benzyl, and —CO—R 6 , and R 6 represents a group selected from: C 1 -C 6 alkyls, phenyl, and benzyl, said method comprising at least one stage of culture of at least one bacterium selected from the Bacillaceae, in the presence of at least two substrates selected from those corresponding to formulas (II) and (III) below: in which A, x 1 , x 2 , R 3 , * and R have the same definition as in formula (I), R 1 , R 2 , independently of one another, represent a group selected from: C 1 -C 6 alkyls, phenyl, benzyl, and —CO—R 4 , and R 4 represents a group selected from: C 1 -C 6 alkyls, phenyl, and benzyl.