Patent ID: 8809369

Claim:
A compound of formula (I) wherein A 1 is nitrogen or —CR 10 —, A 2 is nitrogen or —CH—; A 3 is nitrogen or —CR 9 —; one of R 1 , R 2 and R 10 is -A 4 -SO 2 −R 11 and the other ones are independently selected from the group consisting of hydrogen, alkyl and halogen, A 4 is absent or —NR 12 —C(O)—; R 3 and R 4 are independently selected from the group consisting of alkyl and phenyl, or R 3 and R 4 together with the carbon atom to which they are attached form cycloalkyl, R 5 , R 6 , R 7 , R 8 and R 9 are independently selected from the group consisting of hydrogen, alkyl, haloalkyl, alkoxy, halogen, alkylamino, dialkylamino, hydroxyphenyl, morpholinyl, piperazinyl, alkylpiperazinyl, phenylpiperazinyl, phenylaminocarbonyl, oxo-oxazolidinyl, aminocarbonyl, cyano, alkylsulfonyl, alkylphenyl, alkoxyphenyl, alkylphenylpiperazinyl, dialkylphenylpiperazinyl, halophenylpiperazinyl, alkyl-1H-tetrazolyl, cycloalkyl-1H-tetrazolyl, pyrrolidinyl, carboxyalkylamino and carboxycycloalkylamino, R 11 is selected from the group consisting of alkyl, cycloalkyl, alkylamino, cycloalkylamino and morpholinyl, and R 12 is hydrogen or alkyl; or a pharmaceutically acceptable salt or ester thereof.