Patent ID: 8362243

Claim:
A compound of the formula I, wherein; n represents an integer from 0 to 35; each E, independently of each other, represents: a hydrogen atom; a substituted or unsubstituted phenyl group; a substituted or unsubstituted heterocycle; a nucleobase, optionally substituted with protecting groups; or a DNA intercalator; each R 1 , independently of each other, represents: a hydrogen atom or a side chain of a naturally occurring or non-naturally occurring amino acid; or an optionally substituted alkyl, alkenyl, alkylaryl, aryl, heterocyclic or alicyclic group having up to 20 carbon atoms; wherein at least one of the optionally substituted alkyl, alkenyl, alkylaryl, aryl, heterocyclic or alicyclic groups, having up to 20 carbon atoms, is substituted with one or more phosphonic acid ester functions or phosphononic acid functions; K represents a group of the formula —NR 2 R 3 , —N ⊕ R 2 R 3 R 4 , —NR 2 (CO)R 3 or —NR 2 (CS)R 3 wherein R 2 , R 3 and R 4 , independently of each other, represent: a hydrogen atom; an alkyl, alkaryl, alkenyl, or alkenyl group; an amino protecting group; a reporter ligand; a fluorescence marker; an intercalator; a chelator; an amino acid; a peptide; a protein; a carbohydrate; a lipid; a steroid; a fatty acid; an oligonucleotide; a quantum dot; a FRET quencher (fluorescence resonance energy transfer quencher); or a polymer soluble or insoluble in water; wherein each of the above mentioned groups optionally may be substituted; L represents a group of the formula —NR 5 R 6 , —NR 5 (CO)R 6 , —NR 5 (CS)R 6 , —OR 7 or —SR 7 wherein R 5 and R 6 , independently of each other, represent: a hydrogen atom; an alkyl, alkaryl, alkenyl, or alkinyl group; a reporter ligand; a fluorescence marker; an intercalator; a chelator; an amino acid; an amino acid amide; a peptide; a peptide amide; a protein; a carbohydrate; a lipid; a steroid; a fatty acid; an oligonucleotide; a quantum dot; a FRET quencher (fluorescence resonance energy transfer quencher); or a polymer soluble or insoluble in water; and wherein R 7 represents: a hydrogen atom; an alkyl group; a reporter ligand; a fluorescence marker; an intercalator; a chelator; an amino acid; an amino acid amide; a peptide; a peptide amide; a protein; a carbohydrate; a lipid; a steroid; a fatty acid; an oligonucleotide; a quantum dot; a FRET quencher; or a polymer soluble or insoluble in water; wherein each of the above mentioned groups optionally may be substituted; wherein the K, L or R 1 groups, independently of each other, are substituted with at least one monohydroxy mononitrophenyl group or monohydroxy dinitrophenyl group.