Patent ID: 8440410

Claim:
A method of assessing a prognosis of a patient having a lung tumor of the squamous cell carcinoma subclass, the method comprising steps of: obtaining a tumor sample from a patient with a lung tumor of the squamous cell carcinoma subclass; contacting the tumor sample with a panel of antibodies that includes an antibody directed to biomarker CYP4Z1 and at least one antibody selected from the group consisting of antibodies directed to biomarkers SLC7A5, DDH1 and ABCG2; and assessing the patient's likely prognosis based upon a pattern of binding or lack of binding of the panel to the tumor sample, wherein across a population of patients with lung tumors of the squamous cell carcinoma subclass, a lower level of binding of CYP4Z1 and the at least one antibody selected from the group consisting of antibodies directed to biomarkers SLC7A5, DDH1 and ABCG2 correlates with a higher likelihood that the patient will die from lung cancer or have a recurrence.