Patent ID: 8618090

Claim:
A method of providing prophylaxis to an animal against malaria or treating an animal afflicted with malaria comprising administering to the animal: (i) an effective amount of a compound of formula I: wherein R 1 is hydrogen or alkyl and R 2 is arylalkyl, optionally substituted on the aryl with one or more substituents selected from the group consisting of halo, hydroxyl, nitro, cyano, amino, alkyl, aminoalkyl, alkylamino, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, and formyl; or R 2 is a group of formula (II): wherein n=0 to 6; or R 1 and R 2 together with the N to which they are attached form a heterocycle of formula III: wherein X is N or CH; and Y is aryl, alkylaryl, dialkylaryl, arylalkyl, alkoxyaryl, or heterocyclic, optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, nitro, cyano, amino, aminoalkyl, alkylamino, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, and formyl; and R 3 -R 10 are hydrogen or alkyl; or a pharmaceutically acceptable salt thereof.