Patent ID: 7666861

Claim:
A compound of Formula I, or pharmaceutically-acceptable salts, tautomers or solvates thereof: wherein: X 1 =S; Y 1 =NR 6 ; Y 2 =NR 7 ; Z 1 =O or absent; Q 1 and Q 2 are independently O or S; A 1 and A 2 are independently hydrogen, halo, alkyl, or alkoxy, optionally substituted; n=1; R 1 -R 8 are independently H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, aryl, arylalkyl, arylalkenyl, arylalkynyl, heteroaryl, heteroarylalkyl, heteroaryl alkenyl, heteroaryl alkynyl, or heterocycle, optionally substituted; with a first proviso that when Z 1 =S or O; R 2 is not H; with a second proviso that when n is 1, X 1 is S, Y 1 is NR 6 , Y 2 is O, Z 1 is absent, Q 1 and Q 2 are O, and if R 2 is selected from one of the following groups: methyl, then R 1 is not 3-monomethyl-substituted alkyl, or R 1 is not: where the bond marked with an arrow denotes the point of attachment of the group R 1 to the rest of the molecule.