Patent ID: 8569522

Claim:
A compound of formula I: or a salt thereof, wherein: A 1 is hydrogen, CN, Cl, F, Br, OMe, (1-4C alkyl) or cyclopropyl; A 2 is hydrogen, Cl, Br, F, (1-4C alkyl) or cyclopropyl; W is —C(═O)NR 1 — or —NR 2 C(═O)—; R 1 and R 2 are each hydrogen or methyl; L is a bond, —(CR 3 R 4 ) n —(CR a R b ) m —(CR 5 R 6 )—*, (2-4C)alkenylene, —O(1-4C alkyl)-*, -(1-4C alkyl)-O—*, -(1-4C alkyl)-S—*, (3-6C)cycloalkylene, or hetCyc 1 , wherein the * indicates the point of attachment to G, provided that when W is —NR 2 C(═O)— then L is not —(CH═CH)—; m=0, 1 or 2; n=0 or 1; R a and R b are independently selected from hydrogen and (1-4C alkyl); R 3 is hydrogen, (1-4C alkyl) or CH 2 OH; R 4 is hydrogen or methyl; R 5 is hydrogen, (1-4C alkyl), OH, —O(1-4C alkyl) or F; R 6 is hydrogen, F or methyl, or R 5 and R 6 together with the carbon to which they are attached form a cyclopropyl ring; hetCyc 1 is a group having the formula where t is 1 or 2 and p is 0 or 1, and the * indicates the point of attachment to G; G is Ar 1 , Ar 2 , naphthyl, a benzo-fused (5-6C)cycloalkyl ring optionally substituted with one or more substituents independently selected from Cl and OMe, a benzo-fused 5-6 membered heterocyclic ring having 1-2 heteroatoms independently selected from O and N, a (3-6C)cycloalkyl ring optionally substituted with one or more substituents independently selected from (1-4C)alkyl, an oxaspirononanyl ring, or t-butyl; Ar 1 is phenyl optionally substituted with one or more substituents independently selected from F, Cl, Br, CF 3 , (1-4C)alkyl, OH, —O(1-4C alkyl), —S(1-3C alkyl), —SCF 3 , cyclopropyl, —CH 2 N(1-3C alkyl) 2 , —O-(2-3C)fluoroalkyl, —O-(1-3C)difluoroalkyl —O-(1-3C)trifluoroalkyl, —OCH 2 (cyclopropyl), and (3-4C)alkynyl; Ar 2 is phenyl which is substituted with Ar 3 , —O—Ar 4 , hetAr 1 or —O-hetAr 2 , wherein Ar 2 is optionally further substituted with one or more substituents independently selected from F, Cl and CF 3 ; Ar 3 is phenyl optionally substituted with one or more substituents independently selected from F, Cl, Br and (1-4C alkyl); Ar 4 is phenyl optionally substituted with one or more substituents independently selected from F, Cl, Br and (1-4C alkyl); hetAr 1 is a 6-membered heteroaryl having 1-2 nitrogen atoms and optionally substituted with one or more substituents independently selected from (1-4C alkyl); hetAr 2 is a 6-membered heteroaryl having 1-2 nitrogen atoms and optionally substituted with one or more substituents independently selected from (1-4C alkyl) and CF 3 ; R 7a , R 7b and R 8 are each independently hydrogen or methyl; R 9 is hydrogen, methyl, fluoro or NO 2 ; and R 10 is hydrogen, methyl or fluoro.