Patent ID: 7247641

Claim:
A compound of the following general formula (II): or a pharmaceutically acceptable salt, hydrate, prodrug, or mixtures thereof, wherein: m is 1 and L is —C(R 7 R 8 )—N(R 9 )— or —N(R 9 )—C(R 7 R 8 )— or m is 2, L is —(N(R 9 )) n , and n is 1; R 2 is hydrogen, lower alkyl, hydroxy, halogen, nitro, amino, alkylamino, or carboxy; R 7 and R 8 are independently any of an hydrogen, hydroxyl, halogen, or an optionally substituted amino, nitroso, sulfonamide, lower alkyl, lower alkenyl, C 1 -C 6 straight or branched alkanol, cycloalkyl, heterocycloalkyl, heteroaryl, aryl, alkoxy, aryloxy, alkylamino, arylamino, CH 2 COOH, aralkyl; R 9 is an hydrogen, hydroxyl, optionally substituted amino, nitroso, methyl or lower alkyl, sulfonamide, lower alkenyl, C 1 -C 6 straight or branched alkanol, cycloalkyl, heterocycloalkyl, heteroaryl, aryl, alkoxy, aryloxy, alkylamino, arylamino, CH 2 COOH, aralkyl or —C(O)(C 1 -C 10 alkyl)N(R 5 R 6 ); and R 5 and R 6 are independently hydrogen, optionally substituted lower alkyl, lower alkenyl, C 1 -C 6 straight or branched alkanol, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, alkylhalo, alkoxy, aryloxy, alkylamino, arylamino, alkynyl, aryl, benzyl, arylalkyl, CH 2 COOH, or R 5 and R 6 taken together form a 4, 5, 6, 7, or 8 membered substituted or unsubstituted heterocycloalkyl or cycloalkyl ring containing 1, 2 or 3 heteroatoms selected from O, N, S and combinations thereof, wherein alkyl groups are optionally substituted by mercapto, carboxy, hydroxyl, or phenyl, benzyl or phenylethyl, wherein amino groups are optionally substituted by C 1 -C 10 alkyl, wherein aryl and heteroaryl groups are optionally substituted in 1-5 positions with halo, haloalkyl, hydroxyl, nitro, trifluoromethyl, C 1 -C 10 straight or branched chain alkyl, C 2 -C 10 straight or branched chain alkenyl, C 1 -C 10 alkoxy, —C(O)—O—(C 1 -C 10 alkyl), carboxy, C 2 -C 10 alkenyloxy, phenoxy, benzyloxy, amino, thiocarbonyl, thioester, cyano, imino, alkylamino, aminoalkyl, sulfhydryl, and thioalkyl, and wherein the heterocycloalkyl is a cycloalkyl containing at least 1, 2, 3, or 4 heteroatoms selected from O, N, or S substituted for a ring carbon atom, and may be substituted by or fused to at least one 5 or 6 membered aryl or heteroaryl and/or substituted by at least one of amino, C 1 -C 10 straight or branched chain alkyl, C 1 -C 10 alkanol, C 1 -C 10 straight or branched chain alkylamino, C 1 -C 10 alkoxy, or C 1 -C 10 alkenyl, or benzyl, or phenyl or phenylethyl.