Patent ID: 8357732

Claim:
A method of synthesizing hydroxyapatite nanorods (HAp) having purity, crystallinity, aspect ratio comprises: preparing an ionic solution of calcium ion (Ca 2+ ) by dissolving Ca(NO 3 ) 2 ·4H 2 O salt in deionized water; preparing an ionic solution of phosphate ion (HPO 4 2− ) by dissolving (NH 4 ) 2 HPO 4 salt in deionized water; adding said phosphate ion solution in drop wise into said calcium ion solution with continuous stirring to obtain a reaction mixture; adjusting molar ratio of said calcium to said phosphate ion solutions, Ca/P to about 1.67; performing a chemical precipitation reaction of said reaction mixture under alkaline or acidic conditions to obtain a HAp precursor suspension in water wherein said alkaline condition is obtained by adding urea or ammonia solution to said reaction mixture; performing a hydrothermal treatment of said HAp precursor suspension in water in a 100 ml auto-clave at a temperature about 90 or 200° C. for 60 hrs to obtain suspension of HAp nanorods, washing said suspension of HAp nanorods in a deionized water; performing filtration of said suspension of HAp nanorods by centrifugation to obtain a nanosized Hap rods; and crushing said nanosized HAp rods to powder form.