Patent ID: 8080574

Claim:
A method for treating or delaying the onset of cancer, wherein the cancer is selected from the group consisting of leukemia, non-small cell lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer, and breast cancer, in a subject in need of such treatment, the method comprising administering a therapeutically effective amount of a compound of formula I: wherein X is selected from the group consisting of alkyl and haloalkyl; Ar is selected from the group consisting of phenyl, biphenyl, naphthyl, anthryl, phenanthrenyl, and fluorenyl; wherein Ar is optionally substituted with one or more substituents at any suitable position; R is selected from the group consisting of —CN, —CH 2 CN, —CH 2 CH 2 CN, —CH 2 CH 2 CH 2 CN, or pharmaceutically acceptable salts thereof, to the subject in need of such treatment.