Patent ID: 7253197

Claim:
A compound of formula I: wherein: R 1 is aryl or heteroaryl, wherein at least one of the two meta positions of each aryl and heteroaryl group is substituted with R 5 ; R 2 is hydrogen, alkyl or cycloalkyl; R 3 is cycloalkyl or aryl, wherein at least one of the two ortho positions of each cycloalkyl or aryl group is substituted with R 6 ; R 4 is hydrogen, alkyl or cycloalkyl; R 5 is cyano, trifluoromethyl, alkyl-SO 2 —, amino-SO 2 —, or alkylcarbonyl; and R 6 is hydrogen, halogen, cyano, nitro, trifluoromethyl, alkyl, alkoxy, hydroxy or alkoxycarbonyl; or a pharmaceutically acceptable salt or ester thereof.