Patent ID: RE39593

Claim:
An isolated 1-phenyl-3-dimethylaminopropane diastereoisomer having a configuration corresponding to formula Ia′: X represents OH, F, Cl, H or an OCOR 6 group in which R 6 is a C 1-3 -alkyl group; R 1 is a C 1-4 -alkyl group; R 2 represents H or a C 1-4 -alkyl group, and R 3 is different from R 2 and represents H or a straight chain C 1-4 -alkyl group, and R 5 represents H, and R 4 represents meta-O—Z, where Z is H, C 1-3 -alkyl, PO(OC 1-4 alkyl) 2 , CO(OC 1-5 -alkyl), CONH—C 6 H 4 —(C 1-3 -alkyl) or CO—C 6 H 4 —R 7 , in which R 7 is ortho-OCOC 1-3 -alkyl or meta- or para-CH 2 N(R 8 ) 2 , where R 8 is C 1-4 -alkyl or 4-morpholino, or R 4 represents meta-S-C 1-3 -alkyl, meta-Cl, meta-F, meta-CR 9 R 10 R 11 , ortho-OH, ortho-O—C 2-3 -alkyl, para-F or para-CR 9 R 10 R 11 , where R 9 , R 10 and R 11 independently represent H or F, or R 5 represents para-Cl, para-F, para-OH or para-O—C 1-3 -alkyl, and R 4 represents meta-Cl, meta-F, meta-OH or meta-O—C 1-3 -alkyl, or R 4 and R 5 together represent 3,4-OCH═CH— or 3,4-OCH═CHO—; or a salt thereof with a physiologically acceptable acid.