Patent ID: 7262198

Claim:
A compound of Formula I: wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are hydrogen, lower alkyl, or —C(O)R, in which R is —OR 11 or —NR 11 R 12 , where R 11 and R 12 are independently hydrogen or lower alkyl; or R 1 and R 2 , R 3 and R 4 , R 5 and R 6 , R 7 and R 8 , when taken together with the carbon to which they are attached, represent carbonyl; or with the provisos that i. the maximum number of carbonyl groups is 1, and ii. the maximum number of —C(O)NR 11 R 12 groups is 1, R 10 is benzothiazol-5-yl optionally substituted with alkyl; R 9 and T are taken together are heterocyclyl selected from the group consisting of five and six membered monocyclic and ten to twelve membered bicyclic heterocycles having one or two heteroatoms selected from N and O optionally substituted with 1 to 3 substituents selected from acetyl, alkyl, hydroxy, alkoxy, halogen, halogen substituted alkyl, oxo, phenyl, and phenyl substituted with 1 to 3 substituents selected from alkyl, alkoxy, hydroxy, halogen, or CF 3 ; Q is —N< X is a covalent bond or an alkylene of 1-6 carbon atoms; Y is alkylene of 1-3 carbon atoms; and Z is a covalent bond, —O—, —S—, or —N(R 15 )—, wherein R 15 is hydrogen or C 1-4 alkyl.