Patent ID: 7550487

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: X is C—R 6 ; R 1 is selected from the group consisting of: (1) hydrogen, (2) C 1-7 alkyl, (3) C 3-10 cycloalkyl, (4) C 3-10 cycloalkyl-C 1-7 alkyl, (5) fluoro-C 1-7 alkyl, (6) hydroxy-C 1-7 alkyl, (7) CN—C 1-7 alkyl, (8) hydroxy substituted fluoro-C 1-7 alkyl, (9) C 2-7 alkinyl, (10) R 10 C(O)—, (11) R 10 OC(O)—, (12) N(R 11 ,R 12 )C(O)—, (13) R 10 OC(O)—C 1-7 alkyl, (14) N(R 11 ,R 12 )C(O)—C 1-7 alkyl, (15) R 10 —SO 2 , (16) R 10 —SO 2 —C 1-7 alkyl, (17) N(R 11 ,R 12 )—SO 2 , (18) N(R 11 ,R 12 )—SO 2 —C 1-7 alkyl, (19) aryl-C 1-7 alkyl, (20) heteroaryl, (21) heteroaryl-C 1-7 alkyl, (22) C 1-7 alkoxy-C 1-7 alkyl, (23) C 1-7 alkoxycarbonyl-C 3-10 cycloalkyl-C 1-7 alkyl, and (24) heterocyclyl-C 1-7 alkyl; R 2 is hydrogen or C 1-7 alkyl; R 3 is aryl, aryl-C 1-7 alkyl, heteroaryl or heteroaryl-C 1-7 alkyl; R 4 is hydrogen, C 1-7 alkyl or hydroxy; R 5 , R 6 , R 7 and R 8 independently from each other are selected from the group consisting: of (1) hydrogen, (2) halogen, (3) C 1-7 alkyl, (4) C 1-7 alkoxy, (5) fluoro-C 1-7 alkyl, (6) fluoro-C 1-7 alkyloxy, and (7) CN; R 9 is aryl, heterocyclyl, heteroaryl or heterocyclyl-C(O)—; R 10 is selected from the group consisting of: (1) hydrogen, (2) C 1-7 alkyl, (3) C 3-10 cycloalkyl, (4) C 3-10 cycloalkyl-C 1-7 alkyl, (5) hydroxy-C 1-7 alkyl, (6) fluoro-C 1-7 alkyl, (7) C 1-7 alkyl-SO 2 —C 1-7 alkyl, (8) aryl, (9) aryl-C 1-7 alkyl, (10) heteroaryl, (11) heteroaryl-C 1-7 alkyl, and (12) heterocyclyl; R 11 and R 12 independently from each other are selected from the group consisting of: (1) hydrogen, (2) C 1-7 alkyl, (3) hydroxy-C 1-7 alkyl, (4) fluoro-C 1-7 alkyl, (5) C 3-10 cycloalkyl, (6) C 3-10 cycloalkyl-C 1-7 alkyl, (7) aryl, (8) aryl-C 1-7 alkyl, (9) heteroaryl, and (10) heteroaryl-C 1-7 alkyl; or R 11 and R 12 , together with the nitrogen atom to which they are attached, form a heterocyclic ring selected from the group consisting of: (1) piperidinyl, (2) piperazinyl, (3) morpholinyl, (4) pyrrolidinyl, (5) pyrrolinyl and (6) azetidinyl, which said heterocyclic ring can optionally be substituted with C 1-7 alkyl, halogen or hydroxy.