Patent ID: 7470435

Claim:
A controlled release composition for oral administration, comprising: (1)an immediate release pellet comprising: (a) venlafaxine, its o-desmethylvenlafaxine active metabolite, or a pharmaceutically acceptable salt thereof; (b) an inert sugar pellet; and (c) a binder; (2) an extended release pellet comprising: (i) a core comprising: (a) venlafaxine, its o-desmethylvenlafaxine active metabolite, or a pharmaceutically acceptable salt thereof; (b) an inert sugar pellet; and (c) a binder; (ii) a coating surrounding the core comprising: (a) a water-insoluble polymer; wherein the maximum plasma concentration of venlafaxine, its o-desmethylvenlafaxine active metabolite, or a pharmaceutically acceptable salt thereof, is obtained in less than four hours, and said inert pellet has a diameter rangina from about 15 to about 50 mesh.