Patent ID: 7985763

Claim:
A compound of formula (I): wherein each of R 1 and R 2 , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 3 -C 20 heterocycloalkyl, C 3 -C 20 heterocycloalkenyl, aryl, heteroaryl or C(O)R′, in which R′ is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 3 -C 20 heterocycloalkyl, C 3 -C 20 heterocycloalkenyl, aryl, or heteroaryl; R 3 is C(O)R′, in which R′ is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 3 -C 20 heterocycloalkyl, C 3 -C 20 heterocycloalkenyl, aryl, or heteroaryl; each of X, Y, and Z, independently, is O, N(R a ), S, C 1 -C 10 alkylene, C 2 -C 10 alkenylene, C 2 -C 10 alkynylene, C 3 -C 20 cycloalkylene, C 3 -C 20 heterocycloalkylene, arylene, heteroarylene, —C(O)—, —C(O)O—, —C(O)NR a —, —NR a C(O)NR b —, —NR a C(S)NR b —, —NR a C(O)O—, —SO 2 —, or —SO 2 NR a —, in which each of R a and R b , independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 1 -C 20 heterocycloalkyl, aryl, or heteroaryl; each of U, V, T, and W, independently, is CR′, in which R′ is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 3 -C 20 heterocycloalkyl, C 3 -C 20 heterocycloalkenyl, aryl, heteroaryl, O, or N(R a R b ), in which each of R a and R b , independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, or heteroaryl; is attached to U, V, or T; each of m and n is 0, 1, 2, 3, 4, 5, 6, or 7; p is 1; and each of x, y, and z, independently, is 0 or 1.