Patent ID: 8663944

Claim:
A method for differentiating an individual with osteoarthritis from an individual with rheumatoid arthritis and a normal individual without osteoarthritis in a sample from the individual, comprising measuring in the sample the concentration of cartilage intermediate layer protein 2 C1 (SEQ ID NO: 1) performing a specific competitive ELISA technique with a specific antibody to cartilage intermediate layer protein 2 C1 (SEQ ID NO:1); correlating the concentration of cartilage intermediate layer protein 2 C1 (SEQ ID NO:1) in the sample with the absence or presence of osteoarthritis by determining that the concentration of cartilage intermediate layer protein 2 C1 (SEQ ID NO:1) in the sample from the individual is higher than in a normal control sample; and applying the information on the concentration of cartilage intermediate layer protein 2 C1 (SEQ ID NO:1) to enable correct treatment of the individual for osteoarthritis.