Patent ID: 7750020

Claim:
A compound of the formula wherein R 1 is alkoxy; R 2 is C 3 -C 6 cycloalkyl or C 3 -C 6 heterocyclyl; R 3 is hydrogen, halogen, cyano, lower alkyl or lower alkoxy; R 4 is hydrogen, optionally substituted alkyl, or cycloalkyl; R 5 is —(CR 6 R 7 ) m —W—R 8 in which R 6 and R 7 are independently hydrogen, optionally substituted alkyl or cycloalkyl; or R 6 and R 7 combined are alkylene which together with the carbon atom to which they are attached form a 3- to 7-membered ring; m is zero or an integer from 1 to 5; W is —NR 9 — in which R 9 is hydrogen, optionally substituted alkyl or heterocyclyl; or R 9 is —C(O)R 10 , —C(O)OR 10 , or —C(O)NR 10 R 11 in which R 10 is optionally substituted alkyl, cycloalkyl, aryl, heteroaryl, aralkyl or heteroaralkyl; R 11 is hydrogen or lower alkyl; or R 11 and R 10 combined are alkylene which together with the nitrogen atom to which they are attached form a 4- to 7-membered ring; or W is absent; R 8 is hydrogen, optionally substituted C 1 -C 7 alkyl, cycloalkyl, aryl or heterocyclyl; or R 8 and R 9 combined are alkylene which together with the nitrogen atom to which they are attached form a 4- to 7-membered ring; or R 5 and R 4 combined are alkylene which together with the nitrogen atom to which they are attached form a 4- to 7-membered ring; or R 5 and R 4 taken together with the nitrogen atom to which they are attached form a 6- to 12-membered fused, bridged or spiral bicyclic ring, which may be optionally substituted or may contain 1 to 3 other heteroatoms selected from oxygen, nitrogen and sulfur; or an enantiomer thereof; or an enantiomeric mixture thereof; or a pharmaceutically acceptable salt thereof.