Patent ID: 8110562

Claim:
A compound represented by the structure of formula III: wherein X 2 is O, S, SO, S(O)[=CHCH 2 N(CH 3 ) 2 ], SO 2 , NH, NR, NO, C 1-4 alkylene, C(OH)[CH 2 CH 2 N(CH 3 ) 2 ], C(=CHCH 2 N(CH 3 ) 2 ), PO(C 1-4 alkyl), N[CH 2 CH 2 N(CH 3 ) 2 ], NO[CH 2 CH 2 N(CH 3 ) 2 ]; R is NH 2 , OH, CH 3 ; R 1 is H, halide; A is (CH 2 ) n ; n is 0 or 1; R 3 is H, OH or =O; R 4 is H, oxo (=O), or Q; R 5 is H; or R 5 and R 4 are H and the carbons to which they are attached are connected by a double bond; Y and R 2 independently are H, C 1-4 alkyl, CF 3 , CN or halide; Z is H, CN, NO 2 or halide; and Q is H, CN, NO 2 , halide, C(O)CH 2 NH 2 , C(O)NH(C 1-4 alkyl), C(O)N(C 1-4 alkyl) 2 , C(O)NH 2 , NH(C 1-4 alkyl), NHC(O)NH 2 , NHCO(C 1-4 alkyl) or NHSO 2 (C 1-4 alkyl).