Patent ID: 8835419

Claim:
A compound having formula (I): and any pharmaceutically acceptable salts thereof, wherein R 1 is a member selected from the group consisting of hydrogen, C 1-8 alkyl, C 1-8 haloalkyl, C 1-8 hydroxyalkyl, C 3-8 cycloalkyl, halogen, —CN, —SO 2 Me and —C(O)NH 2 ; each R 2 is a member selected from the group consisting of C 1-8 alkyl, C 1-8 haloalkyl, halogen, —CN and C 1-8 alkoxy; or two R 2 groups attached to adjacent carbon atoms are optionally connected to form a 5- or 6-member ring which is optionally substituted with additional R 2 groups; R 3 is a member selected from the group consisting of hydrogen, methyl and C 1-4 haloalkyl; R 4 is a member selected from the group consisting of hydrogen, C 1-8 alkyl, C 1-8 haloalkyl and C 1-8 hydroxyalkyl; each of the subscripts n is independently an integer from 0 to 3; B is a bond or C(O); Q is a member selected from the group consisting of C, CH, N, O, S, S(O) and SO 2 ; W, X, Y, and Z are independently selected from the group consisting of C, CH and N, but Q and W are not both N; R 5 and R 6 are absent or are members independently selected from the group consisting of H, —OH, C 1-8 alkyl, C 1-8 hydroxyalkyl, C 1-4 alkoxy-C 1-4 alkyl, —C(O)NR a R b , C 1-8 alkylene-C(O)NR a R b , —NH—C 1-4 alkylene-C(O)NR a R b , —C(O)—C 1-4 alkylene-NR a R b , —CO 2 H and acid isosteres, C 1-8 alkylene-CO 2 H and acid isosteres, —N(R a )C(O)NR a R b , C 1-8 alkylene N(R a )C(O)NR a R b , —NR a R b , C 1-8 alkylene-NR a R b , C 1-8 alkoxy, —C(O)OR a , C 1-8 alkylene-C(O)OR a , —CN, —C(O)R a , —SO 2 R a and —N(R a )C(O)R b ; wherein each R a and R b are independently selected from the group consisting of hydrogen, C 1-8 alkyl, C 1-8 hydroxyalkyl, C 1-8 haloalkyl, and C 1-8 alkoxy; and R 7 is absent or is selected from the group consisting of H, C 1-8 alkyl and C 1-8 haloalkyl.