Patent ID: 8835470

Claim:
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: Q is R 1 is: (i) C 3-6 alkyl; (ii) C 3-7 cycloalkyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; (iii) phenyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; or (iv) pyridinyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; R 2 is C 1-6 alkyl, C 1-3 fluoroalkyl, C 3-7 cycloalkyl, or phenyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; n is zero, 1, or 2; each R 3 is independently C 1-3 alkyl, F, Cl, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, —CN, C 1-3 alkoxy, and/or C 1-3 fluoroalkoxy; R 4 is H or —CH 3 ; R 5 is H or —CH 3 ; and G is: (i) H, C 1-6 alkyl, or C 3-6 cycloalkyl; (ii) C 1-6 alkyl substituted with —NH 2 , C 1-6 alkoxy, —C(O)OH, —C(O)O(C 1-6 alkyl), or —S(O) 2 C 1-6 alkyl; (iii) C 1-6 alkyl substituted with one or more substituents selected from —OH, —CN, and/or cyclopropyl; (iv) —(CH 2 ) 0-3 —R a , wherein R a is C 3-6 cycloalkyl substituted with zero to 2 substituents independently selected from —OH, —CN, and/or —CH 2 OH; (v) —(CH 2 ) 0-3 —R b , wherein R b is phenyl substituted with zero to 2 substituents independently selected from —OH, C 1-3 hydroxyalkyl, and/or —S(O) 2 NH 2 ; (vi) —(CH 2 ) 1-3 C(O)NR c R d , wherein R c is H or —CH 3 ; and R d is H, C 1-6- alkyl, C 3-6 cycloalkyl, C 1-6 hydroxyalkyl, —(CH 2 ) 0-2 (heteroaryl), or —(CH 2 ) 0-2 (heterocyclyl); (vii) —CH(CN)R e , wherein R e is phenyl, benzyl, —C(O)NH 2 , or —C(O)NH(C 1-3 alkyl); (viii) —CHR f C(O)NH(CH 3 ), wherein R f is C 1-6 alkyl, —CN, phenyl, benzyl, or —CH 2 CH 2 -phenyl; (ix) —(CH 2 ) 1-3 NHC(O)R g , wherein R g is C 1-6 alkyl or —O(C 1-6 alkyl); (x) —CHR h —(CH 2 ) 0-3 —R i , wherein R h is H or —CH 3 , and R i is heteroaryl; (xi) —(CH 2 ) 0-3 —R j , wherein R j is heterocyclyl; or (xii) —(CH 2 ) 1-3 C(O)—R k , wherein R k is and each R x is independently selected from H, F, —OH, —CH 3 , —OCH 3 , and/or —C(O)OCH 3 ; wherein each of said heteroaryl groups is substituted with zero to three substituents independently selected from C 1-3 alkyl, —OH, —NH 2 , phenyl, methylphenyl, benzyl, —CH 2 CH 2 -phenyl, pyridinyl, —C(O)OC 1-3 alkyl, and/or —CH 2 OCH 3 ; and wherein each of said heterocyclyl groups is substituted with zero to three substituents independently selected from C 1-3 alkyl, —OH, —NH 2 , phenyl, methylphenyl, benzyl, —CH 2 CH 2 -phenyl, pyridinyl, —C(O)OC 1-3 alkyl, ═O, and/or —CH 2 OCH 3 .