Patent ID: 8853255

Claim:
A method of treating a patient that is suffering from a disorder or disease that is treated by the inhibition of the serotonin and/or the norepinephrine transporter, comprising administering a therapeutically effective amount of a compound of formula I: where: R 1 is selected from —CH 2 OH, —C 1-2 alkylene-O—C 1-6 alkyl, —C 1-2 alkylene-S—C 1-6 alkyl, —C 1-2 alkylene-O-phenyl, —C 1-2 alkylene-S-phenyl, —C 1-2 alkylene-O-benzyl, —C 1-2 alkylene-S-benzyl, tetrahydropyranyl, and tetrahydrofuranyl; and R 2 through R 6 are independently selected from hydrogen, halo, —C 1-6 alkyl, —CF 3 , —O—C 1-6 alkyl, —CN, —C(O)—C 1-6 alkyl, —S—C 1-6 alkyl, —C 3-8 cycloalkyl, and —NO 2 ; or R 4 and R 5 are taken together to form —CH═CH—CH═CH—; or R 5 and R 6 are taken together to form —CH—CH═CH—CH—; or a pharmaceutically acceptable salt thereof; wherein the disorder or disease is selected from a pain disorder, a depressive disorder, an affective disorder, attention deficit hyperactivity disorder, a cognitive disorder, stress urinary incontinence, chronic fatigue syndrome, obesity, and vasomotor symptoms associated with menopause.