Patent ID: 7494646

Claim:
A method of delivering a cytotoxic agent or a diagnostic agent to a cell that expresses a STEAP-1 protein (SEQ ID NO:2), comprising providing a cytotoxic agent, a therapeutic agent or a diagnostic agent conjugated to: (a) an antibody or antibody fragment, comprising all heavy and light chain complementarity determining regions (CDRs) from an antibody designated X92.1.30.1.1(1) (ATCC Accession number PTA-5802) or X120.545.1.1 (ATCC Accession number PTA-5803), or (b) an antibody or antibody fragment, comprising the heavy chain variable region sequence of SEQ ID NO:50 and a light chain variable region sequence selected from the group consisting of SEQ ID NO:52, SEQ ID NO:54 and SEQ ID NO:56, wherein the antibody or antibody fragment of (a) and (b) binds to the STEAP-1 protein (SEQ ID NO: 2), to form an antibody-agent or antibody fragment-agent conjugate; and exposing the cell to the antibody-agent or antibody fragment-agent conjugate.