Patent ID: 7033823

Claim:
A cell-cultivating device, comprising: a first chamber having a first end, a second end, an interior surface, and an exterior surface, wherein the interior surface has at least one structure to receive at least one cell and allow cell anchorage and/or adhesion, and wherein a gaseous environment is disposed within the first chamber; a second chamber connected to the second end of the first chamber, the second chamber having a first end, a second end, an interior surface, and an exterior surface, the second chamber being a compressible body; and communicating means disposed between the second end of the first chamber and the first end of the second chamber; wherein culture medium is disposed within the second chamber, the culture medium being movable between the first and the second chambers through the communicating means when the second chamber is compressed and decompressed, such that when the second chamber is compressed the structure where at least one cell is anchored and/or adhered is submerged by the culture medium, and when the second chamber is decompressed the structure where at least one cell is anchored and/or adhered emerges from the culture medium and is indirectly exposed to the gaseous environment of the first chamber through a thin gas-growth medium interface to provide oxygenation.