Patent ID: 8541455

Claim:
A compound of formula (I): wherein R represents —SO 2 —NR3R4 or —SO 2 —R4; R3 and R4 being as defined below; R1 represents —W-aryl, the said aryl being optionally substituted on at least one carbon atom with at least one substituent chosen from halogen, (C1-C5)alkyl, —(C1-C5)alkylene-O—(C1-C5)alkyl, —(C1-C5)alkoxy, hydroxy, -halo(C1-C5)alkyl, cyano, —O(C1-C5)alkylene-O—(C1-C5)alkyl, —O—(C1-C5)alkylene-NR5R6, —SO 2 —(C1-C5)alkyl, —NR5R6 and —CO 2 R5, R2 represents hydrogen, —(C1-C5)alkyl, —(C1-C5)alkylene-O—(C1-C5)alkyl, -halo(C1-C5)alkyl, —W—COOR5, —W—C(O)NHR5 or —W—C(O)—NR5R6; W, R5 and R6 being as defined below; it being understood that: n represents 0, 1 or 2; W is (i) —(C1-C5)alkylene-, optionally substituted with a group chosen from —(CH 2 )n-CO 2 R5 and —(CH 2 )n-(CO)NR5R6, with n as defined above and R5 and R6 as defined below; or (ii) —(C3-C6)cycloalkylene-, R3 and R4 which may be identical or different, represent, independently of each other, hydrogen, —(C1-C5)alkyl, —(C3-C6)cycloalkyl, —(C1-C5)alkylene-O—(C1-C5)alkyl, aryl, —CH 2 -aryl, —W—OH, —W—CHOH—CH 2 OH, —W—CO 2 R5, —W—NR5R6 or —W—O—(CH 2 )n-aryl; the said —(C3-C6)cycloalkyl being optionally substituted on at least one carbon atom with at least one group chosen from —(C1-C5)alkyl, —(C1-C5)alkoxy, hydroxy, —W—NR5R6 and —W—CO 2 R5, with W and n as defined previously and R5 and R6 as defined below and provided that when R3 and R4 are identical, they cannot be hydrogen; and R5 and R6, which may be identical or different, represent, independently of each other, hydrogen, —(C1-C5)alkyl or —(C1-C5)haloalkyl, in the form of the base or an acid-addition salt.