Patent ID: 7354599

Claim:
A pharmaceutical liposomal formulation for photodynamic therapy, which is stable to freeze-drying and reconstitution, comprising: a liposomal bilayer, said bilayer consisting substantially of synthetic phospholipids; a monosaccharide; a therapeutically effective amount of a hydrophobic photosensitizer, wherein said hydrophobic photosensitizer is temoporfin; wherein said monosaccharide is selected from the group consisting of fructose and glucose; wherein said synthetic phospholipids of said liposomal bilayer are dipalmitoyl phosphatidyl choline, and dipalmitoyl phosphatidyl glycerol, with a weight ratio of dipalmitoyl phosphatidyl choline to dipalmitoyl phosphatidyl glycerol of about 10:1; and wherein the weight ratio of phospholipids to monosaccharide is between 1:2 and 1:12.