Patent ID: 6878805

Claim:
An oligomeric compound having formula I: wherein: one of T 1 , T 2 , and T 3 is L—R 2 ; another of T 1 , T 2 , and T 3 is hydrogen, hydroxyl or a protected hydroxyl; the remaining of T 1 , T 2 , and T 3 is hydrogen, L—R 2 or an optionally protected sugar substituent group; each L is a linking moiety; each R 2 is, independently, an amphipathic peptide having formula II: —X 1 —(X 2 ) 2 —(X 3 ) 2 —X 2 —X 4 —X 3 —X 4 —X 2 —X 4 —X 3 —(X 2 ) 2 — (II) wherein each X 1 is glycine; each X 2 is, independently, lysine, arginine, ornithine or homoarginine; each X 3 is, independently, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, tryptophan, cysteine, or methionine; and each X 4 is, independently, lysine, arginine, ornithine, homoarginine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, tryptophan, cysteine, methionine, glycine, serine, threonine, aspartate, glutamate, asparagine, or glutamine; each Bx is an optionally protected heterocyclic base moiety; each R 1 is, independently, hydrogen or an optionally protected sugar substituent group; each X is, independently, S or O; and n is from 2 to about 50.