Patent ID: 7897338

Claim:
A mobility-modified sequence-specific nucleobase polymer comprising a mobility-modifying polymer linked to a sequence-specific nucleobase polymer, according to Structural formula (II) or (III): or a salt thereof, wherein: R 2 is selected from the group consisting of alkyl comprising at least two carbon atoms, aryl, (R 8 ) 3 Si— where each R 8 is independently selected from the group consisting of linear and branched chain alkyl and aryl, base-stable protecting groups, and R 5 —X—[(CH 2 ) a —O] b —(CH 2 ) a —; each R 10 is independently selected from the group consisting of hydrogen and R 2 ; R 5 is selected from the group consisting of hydrogen, protecting group, reporter molecule, and ligand; each R 4 is independently selected from the group consisting of hydrogen and R 2 ; each X is O; each a is independently an integer from 1 to 6; each b is independently an integer from 0 to 40; each d is independently an integer from 1 to 200; and OLIGO is a sequence-specific nucleobase polymer, with the proviso that at least one R 10 or at least one R 4 is other than hydrogen.