Patent ID: 7041700

Claim:
A benzopyran compound of formula (1) or formula (2), or a pharmaceutically acceptable salt thereof: wherein R 1 and R 2 represent independently of each other hydrogen atom or C 1-6 alkyl group, wherein said alkyl group may be optionally substituted with halogen atom, C 1-6 alkoxy group or hydroxyl group; R 3 represents hydroxyl group or C 1-6 alkylcarbonyloxy group; R 4 hydrogen atom or C 1-6 alkyl group; R 5 represents either (a) C 1-6 alkyl group substituted with C 6-14 aryl group or heteroaryl group, wherein said C 1-6 alkyl group may be optionally substituted with hydroxyl group or methyl group, and said C 6-14 aryl group or heteroaryl group may be optionally substituted with 1 to 3 R 7 , wherein R 7 represents halogen atom, nitro group, cyano group, hydroyxl group, formyl group, formamide group, amino group, C 1-6 alkyl group optionally substituted with halogen atom, C 1-6 alkoxy group optionally substituted with halogen atom, C 3-6 cycloalkyl group, C 1-6 alkylamino group, di-C 1-6 alkylamino group, C 1-6 alkylcarbonylamino group, C 1-6 alkylsulfonylamino group, aminocarbonyl group, C 1-6 alkylaminocarbonyl group, di-C 1-6 alkylaminocarbonyl group, C 1-6 alkylcarbonyl group, C 1-6 alkoxycarbonyl group, aminosulfonyl group, C 1-6 alkylsulfonyl group, carboxyl group or benzoyl group wherein said benzoyl group may be optionally substituted with C 1-6 alkyl group, C 1-6 alkoxy group, halogen atom, nitro group or cyano group, or (b) straight-chain C 5-8 alkyl group, wherein said C 5-8 alkyl group may be optionally substituted with fluorine atom or hydroxyl group; R 6 represents (a) C 1-6 alkyl group, wherein said alkyl group may be optionally substituted with hydroxyl group, carboxyl group, amino group, C 1-6 alkylamino group, di-C 1-6 alkylamino group, C(O)OR 8 NHSO 2 R 8 , C(O)NH 2 , C(O)NHR 8 , or C(O)NR 8 R 9 , wherein R 8 and R 9 represent independently of each other C 1-6 alkyl group substituted with C 6-14 aryl group or heteroaryl group or C 1-6 alkyl group, (b) C 1-6 alkoxy group, (c) halogen atom, (d) nitro group, (e) C(O)NH 2 , (f) C(O)NHR 8 or (g) C(O)NR 8 R 9 wherein R 8 and R 9 represent independently of each other C 1-6 alkyl group substituted with C 6-14 aryl group or heteroaryl group or C 1-6 alkyl group; with a proviso that 4-benzylamino-3,4-dihydro-3-hydroxy-2,2-dimethyl-N-(2-phenylethyl)-2H-1-benzopyran-6-carboxamide and 4-(3-bromo-4-fluorobenzyl)amino-6-ethyl-3,4-dihydro2,2-dimethyl-2H-1-benzopyran-3-ol are excluded.