Patent ID: 8691861

Claim:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein Ar is an aromatic ring selected from the group consisting of benzene, pyridine and pyrimidine; m is an integer from 0-5; each R a is independently selected from the group consisting of cycloalkyl, haloalkyl, halogen, —OH, —OR 1 , —OSi(R 1 ) 3 , —OC(O)O—R 1 , — OC(O)R 1 , —OC(O)NHR 1 , —OC(O)N(R 1 ) 2 , —SH, —SR 1 , —S(O)R 1 , —S(O) 2 R 1 , —SO 2 NH 2 , —S(O) 2 NHR 1 , —S(O) 2 N(R 1 ) 2 , —NHS(O) 2 R 1 , —NR 1 S(O) 2 R 1 , —C(O)NH 2 , —C(O)NHR 1 , —C(O)N(R 1 ) 2 , —C(O)R 1 , —C(O)H, — C(═S)R 1 , —NHC(O)R 1 , —NR 1 C(O)R 1 , —NHC(O)NH 2 , —NR 1 C(O)NH 2 , —NR 1 C(O)NHR 1 , —NHC(O) NHR 1 , —NR 1 C(O)N(R 1 ) 2 , —NHC(O)N(R 1 ) 2 , —CO 2 H, —CO 2 R 1 , —NHCO 2 R 1 , —NR 1 CO 2 R 1 , — R 1 , —CN, —NO 2 , —NH 2 , —NHR 1 , —N(R 1 ) 2 , —NR 1 S(O)NH 2 , —NR 1 S(O) 2 NHR 1 , —NH 2 C(═NR 1 )NH 2 , — N═C(NH 2 )NH 2 , —C(═NR 1 )NH 2 , —NH—OH, —NR 1 —OH, —NR 1 —OR 1 , —N═C═O, —N═C═S, —Si(R 1 ) 3 , — NH—NHR 1 , —NHC(O)NHNH 2 , NO, —N═C═NR 1 and —S—CN, wherein each R 1 is independently alkyl or aryl; L is a linking group selected from the group consisting of a bond, CH 2 and SO 2 ; Q a , Q b , and Q c are each members independently selected from the group consisting of N, S, O and C(R q ) wherein each R q is independently selected from the group consisting of H, C 1-8 alkyl, halogen and phenyl; and Y is C or N; and the ring having Q a , Q b , Q c and Y as ring vertices is a five-membered ring having two double bonds.