Patent ID: 7390463

Claim:
A fluidic device for performing high-throughput biological or chemical assays, the device comprising: a support structure with a first surface and a second surface; a number of microcolumns extending from said first surface; each of said microcolumns having a first and a second fluidic channel formed therein and a planar, major surface remotely located relative to said first surface; said first fluidic channel having an inlet port and extending through said microcolumn from said second surface of said support structure through said remote planar, major surface; said second fluidic channel extending at least partially through said microcolumn from said remote planar, major surface to an outlet portal; and a microplate having a plurality of wells wherein each microcolumn is sized so as to be introduced into the corresponding well of said microplate; wherein each of said microcolumns has a sealing mechanism that engages with a bottom wall of said well to form a fluid-tight space.