Patent ID: 8580857

Claim:
A method for determining a therapeutically effective amount of suramin for administering to a patient, who is to receive a cytotoxic agent, which comprises the steps of: (a) determining the gender and the squared value of the body surface area (BSA) of said patient; (b) determining the time elapsed, in days, since the initiation of the last suramin treatment; and (c) calculating the dose of low dose suramin using a nomogram that shows the dose according to the parameters of gender, squared value of body surface area, and elapsed days since last suramin treatment, wherein said nomogram comprises: Nomogram for Calculating Suramin Dose Cycle 1* Days elapsed since FACTOR the initiation Man Woman of the last 125 125 suramin treatment FACTOR 7 39 33 8 43 37 9 47 40 10 51 44 11 55 47 12 58 50 13 61 53 14 64 56 15 67 58 16 70 61 17 72 63 18 74 66 19 77 68 20 79 70 21 80 72 22 82 74 23 84 75 24 86 77 25 87 79 26 88 80 27 90 82 28 91 83 29 92 84 30 93 86 31 94 87 32 95 88 33 96 89 34 97 90 35 98 91 36 98 92 37 99 93 38 100 94 39 100 95 41 102 96 42 102 97 44 103 98 47 104 100 49 105 101 52 106 102 55 106 103 where: Dose (mg)=FACTOR*BSA 2 wherein “BSA” is body surface area in units of m 2 .