Patent ID: 8062350

Claim:
A method comprising implanting in a human being a medical device comprising a chemo-attractant attached to a surface layer of polymer on the medical device, wherein the chemo-attractant is attached to the surface layer through a spacer compound comprising a hydrophobic moiety and a hydrophilic moiety, said hydrophobic moiety comprising a phospholipid, wherein the chemo-attractant is attached to the hydrophilic moiety of the spacer compound, wherein the hydrophobic moiety of the spacer compound is grafted to or embedded within the surface layer of polymer on the medical device, and wherein the hydrophilic moiety of the spacer compound projects from the surface layer of polymer, wherein the method treats or ameliorates a medical condition selected from atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, urethra obstruction, tumor obstruction, diabetic vascular disease, and combinations thereof.