Patent ID: 8030311

Claim:
A compound of the formula I, wherein each of R1 and R2, independently of the other, is selected from the group consisting of hydrogen, halo and C 1 -C 7 -alkyl; R3 is absent if Z is nitrogen or, if Z is C, then R3 is hydrogen, unsubstituted or substituted aryl or unsubstituted or substituted heterocyclyl; X is N (nitrogen) or CH (hydrogen-substituted carbon), Y is CH or N, Z is C or N, and Q is a moiety of the formula (A) wherein R4 is hydrogen, halo, unsubstituted or substituted amino, unsubstituted or substituted aryl, unsubstituted or substituted heterocyclyl bound via a ring atom other than nitrogen, unsubstituted or substituted cycloalkyl, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl or unsubstituted or substituted alkynyl; R5 is hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted amino, unsubstituted or substituted aryl or unsubstituted or substituted heterocyclyl; and R6 is hydrogen, unsubstituted or substituted cycloalkyl or unsubstituted or substituted alkyl; or a moiety of the formula (B) wherein R7 is unsubstituted or substituted aryl or unsubstituted or substituted heterocyclyl and R8 is alkyl or cycloalkyl; where the asterisk * in formulae (A) and (B) marks the bond through which the moiety is bound to the NH of the amide group in formula I; and (a) each of R9 and R10, independently of the other, is selected from the group consisting of hydrogen, hydroxyl and C 1 -C 7 -alkyl; or (b) R9 and R10 together represent oxo; or R1 and R9 together form a group —C(O)—CH2—or —CH2—CH2—, R2 is selected from the group consisting of hydrogen, halo and C 1 -C 7 -alkyl, and R10 represents hydrogen; or a pharmaceutically acceptable salt thereof.