Patent ID: 8846643

Claim:
A compound having the structure of Formula (I): wherein B N is a substituted or unsubstituted nucleobase; L 1 is a bond or —O—; R 1 is halogen, —CF 3 , unsubstituted alkyl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted aryl; provided that, if L 1 is a bond, then R 1 is halogen, and if L 1 is —O—, then R 1 is —CF 3 , unsubstituted alkyl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted aryl; R 2 is L 2 -O—R 3 (II), wherein L 2 is a substituted or unsubstituted alkylene, substituted or unsubstituted cycloalkylene, or substituted or unsubstituted arylene; and R 3 is substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted aryl; or pharmaceutically accepted salt or solvate thereof.