Patent ID: 8598357

Claim:
A compound of formula (I) wherein n is 0, 1, 2 or 3; Y is —C(O)— or —S(O) 2 —; R 1 is hydrogen, halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, —NR 7 R 8 , —C(O)—NR 7 R 8 , or —S(O) 2 —R 9 ; wherein alkyl, haloalkyl, and alkoxy are each optionally substituted by one, two or three independent R 5 ; and wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are each optionally substituted by one, two or three independent R 6 ; R 2 , R 3 , and R 4 are each independently hydrogen, halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy or haloalkoxy; R 5 is cyano, hydroxy, alkoxy, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are each optionally substituted by one, two or three independent R 6 ; R 6 is halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, oxo, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; R 7 and R 8 are each independently hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heterocycloalkylalkyl, aryl, or heteroaryl; wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are each optionally substituted by one, two or three independent R 10 ; R 9 is alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, or —NR 7 R 8 ; wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are each optionally substituted by one, two or three independent R 11 ; R 10 is halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, or oxo; and R 11 is halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, or oxo; or a pharmaceutically acceptable salt or ester thereof.