Patent ID: 7074833

Claim:
A method for limiting the risk of cardiovascular disturbances and/or the risks of organ and/or tissue toxicity in the treatment of a living animal body afflicted with disorders which may be treated by double inhibition of serotonin (5-HT) and norepinephrine (NE) reuptake, said method comprising administering to the living animal body an effective amount of a mixture of enantiomers of milnacipran (Z(Â±)-2-(amino methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide), as well as their pharmaceutically-acceptable salts, other than the hydrochloride salt, such mixture being substantially pure in the (1S,2R) enantiomer, wherein the administration of said mixture limits the risks of cardiovascular disturbances and/or the risks of organ and/or tissue toxicity, relative to administration of racemic milnacipran.