Patent ID: 8821929

Claim:
A process of preparing a solid oral extended release pharmaceutical dosage form comprising an extended release matrix comprising a composition, said process comprising the steps of: (a) combining at least (1) at least one polyethylene oxide having, based on rheological measurements, an approximate molecular weight of 4,000,000, and (2) oxycodone or a pharmaceutically acceptable salt thereof to form a blend; (b) shaping said blend to form a shaped tablet; and (c) convection curing said shaped tablet by subjecting the shaped tablet to a temperature from about 60 to about 90° C. for a time of from about 15 minutes to about 10 hours, wherein said convection cured shaped tablet comprises: (i) 5, 7.5, 10, 15, 20, or 30 mg of said oxycodone or pharmaceutically acceptable salt thereof and at least 79% by weight, based upon the total weight of said composition, of said at least one polyethylene oxide; (ii) 40 mg of said oxycodone or pharmaceutically acceptable salt thereof and at least 72% by weight, based upon the total weight of said composition, of said at least one polyethylene oxide; (iii) 60 mg of said oxycodone or pharmaceutically acceptable salt thereof and at least 57% by weight, based upon the total weight of said composition, of said at least one polyethylene oxide; or (iv) 80 mg of said oxycodone or pharmaceutically acceptable salt thereof and at least 54% by weight, based upon the total weight of said composition, of said at least one polyethylene oxide.