Patent ID: 8535887

Claim:
A method of testing an individual having a chronic infection with a hepatitis C virus (HCV) for the presence or absence of at least one IFN-α response marker in Table 1 below, Better Heterozygous Homozygous Response IFN-α Response IFN-α Response PS SNP Allele Marker Marker rs12979860 T/C C C/T genotype C/C genotype rs28416813 G/C G G/C genotype G/G genotype rs8103142 A/G A A/G genotype A/A genotype rs12980275 A/G A A/G genotype A/A genotype rs8099917 A/C A A/C genotype A/A genotype rs12972991 T/G T T/G genotype T/T genotype rs8109886 A/C C C/A genotype C/C genotype rs4803223 T/C T T/C genotype T/T genotype rs12980602 A/G A A/G genotype A/A genotype the method comprising obtaining a nucleic acid sample from the individual and assaying the nucleic acid sample to determine the individual's genotype at a polymorphic site (PS) in Table 1, wherein if the individual is heterozygous or homozygous for the better response allele for said PS, then the IFN-α response marker is present and if the individual is homozygous for the other allele for said PS, then the IFN-α response marker is absent.