Patent ID: 8741951

Claim:
A compound of formula I: wherein R is selected from the group consisting of: aryl, optionally substituted aryl, heteroaryl, optionally substituted heteroaryl, straight or branched C 2-10 heteroalkyl, substituted straight or branched C 2-10 heteroalkyl, C 1 -C 4 -arylalkyl, substituted C 1 -C 4 -arylalkyl, C 1-4 heteroarylalkyl, and substituted C 1-4 heteroarylalkyl; X is oxygen, sulfur, sulfinyl (—SO—), sulfonyl (—SO 2 —), —NR n —, —PR n —, or —Se—, where R n is H, or C 1 -C 4 alkyl; R 1 and R 6 are the same or different and each is independently selected from the group consisting of H, C 1-4 alkyl, halogen, —NO 2 , —CN, —SiR i 3 , —NHCOCF 3 , —NHCOR i , —NHCONHR i , —NHCOOR i , —OCONHR i , —CONHR i , —NHCSCF 3 , —NHCSR i , —NHSO 2 R i , —NCS—OR i , —COR i , —COOR i , —OSO 2 R i , —SO 2 R i , —S—R i , —R ii , and —R iii , wherein R i is H, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 di-haloalkyl, C 1-4 tri-haloalkyl, C 1-4 perfluoro-alkyl, aryl, halogen, or C 2-4 alkenyl; R ii is a fused ring with the phenyl residue, formed as R 1 and R 6 are joined together, selected from the group consisting of: X 5 is S, SO 2 , SO, or O; R iii is (C 1 -C 4 )-halo alkyl, C 1-4 di-haloalkyl, (C 1 -C 4 )-tri-haloalkyl, (C 1 -C 4 )-perfluoro-alkyl, or CF 2 CF 3 ; R 5 is H, or C 1 -C 4 -alkyl; R 4 is H, F, Cl, I or Br; and R 2 and R 3 are the same or different and each is independently selected from the group consisting of H, C 1-4 alkyl, —CN, carbamoyl methyl, —NO 2 , halogen, C 1-4 alkoxy, C 1-4 alkanoyl, C 1-4 thio-alkyl, C 1-4 alkyl-sulphinyl, C 1-4 alkyl-sulphonyl, C 1-4 perfluoro-alkyl, C 1-4 perfluoro-thio-alkyl, C 1-4 perfluoro-alkyl-sulphinyl, and C 1-4 perfluoro-alkyl-sulphonyl, with the condition that the C 1-4 alkyl, the C 1-4 alkoxy, the C 1-4 alkanoyl, the C 1-4 thio-alkyl, the C 1-4 alkyl-sulphinyl, the C 1-4 alkyl-sulphonyl, the C 1-4 perfluoro-alkyl, the C 1-4 perfluoro-thio-alkyl, the C 1-4 perfluoro-alkyl-sulphinyl, the C 1-4 perfluoro-alkyl-sulphonyl are each optionally bound to a C 1-4 alkyl, a phenyl, a thio-phenyl, a sulphinyl-phenyl, or a sulphonyl-phenyl.