Patent ID: 8309765

Claim:
A process for the preparation of D-(−)-N,N-diethyl-2-(α-naphthoxy) propionamide comprising in order: (a) reacting (L)-2-(−)halopropionic acid with a chlorinating agent and dimethylformamide to form (L)-2-(+)-halopropionyl chloride; (b) reacting the (L)-2-(+)-halopropionyl chloride with diethyl amine in presence of an aqueous solution of alkali metal hydroxide to form (L)-(+)-2-halo-N,N-diethyl propionamide; and (c) reacting the mass containing (L)-(+)-2-halo-N,N-diethyl propionamide, with α-naphthol in the presence of aqueous alkali metal hydroxide to form D-(−)-N,N-diethyl-2-α-naphthoxy)propionamide.