Patent ID: 8193333

Claim:
A pharmaceutical composition comprising, in an acceptable carrier, at least: a double-stranded short interfering nucleic acid molecule specific to the Bcl-X L transcript comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and wherein each strand comprises 15 to about 30 nucleotides, and each strand comprises 15 to about 30 nucleotides that are complementary to the nucleotides of the other strand, and a short interfering nucleic acid molecule targeting the Mcl-1 transcript consisting of a sense strand of the sequence SEQ ID NO: 7 and an antisense strand of the sequence SEQ ID NO: 8.