Patent ID: 7713974

Claim:
A compound according to formula I wherein: A is A-2 wherein X 2 and one of X 1 and X 3 are N and the other of X 1 and X 3 is CR 3 ; R 1 is fluorine or hydrogen; R 2 is hydrogen, halogen, C 1-6 alkyl, C 3-7 cycloalkyl, C 1-6 haloalkyl, C 1-6 alkoxy, or C 1-6 alkylsulfonyl; Ar is phenyl substituted with one to three groups independently selected in each occurrence from the group consisting of hydrogen, halogen, cyano, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl and C 3-7 cycloalkyl; R 3 is independently selected in each occurrence from the group consisting of: (i) hydrogen, (ii) hydroxy, (iv) halogen, (v) NR 4a R 4b , (vi) C 1-6 acylamino, (vii) C 1-6 alkylsulfonylamino, (viii) cyano, (ix) nitro, (x) NHNH 2 ; and (xi) phenyl optionally substituted with one to three substituents independently selected from the group consisting of halogen, C 1-6 alkyl, C 1-6 alkoxy, cyano, intro; R 4a and R 4b are independently hydrogen or C 1-6 alkyl; R 5 is hydrogen or C 1-3 alkyl; R 6 is hydrogen or C 1-6 alkyl; and, pharmaceutically acceptable salt thereof.