Patent ID: 8288419

Claim:
A compound of formula (I), wherein A represents a phenyl- or a monocyclic heterocyclyl-group, wherein the phenyl- or monocyclic heterocyclyl-group is substituted in a 1,3-arrangement; or A represents propan-1,3-diyl; E represents *-(C 1 -C 4 )alkyl-Oâ€”, â€”CHâ•CHâ€” or wherein the asterisks indicate the bond which is linked to R 1 ; Q represents O, or S; R 3 represents hydrogen, (C 1 -C 4 )alkyl, cyclopropyl, (C 1 -C 4 )alkoxy-(C 1 -C 2 )alkyl, â€”CH 2 NH 2 , â€”CH 2 NHBoc, â€”CH 2 CH 2 C(O)OtBu or benzyl; R 1 represents a heterocyclyl- or an aryl-group, which group is unsubstituted, mono-, di- or tri-substituted, with halogen, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, (C 1 -C 4 )fluoroalkyl, (C 1 -C 4 )fluoroalkoxy, phenyl, cyano, di-[(C 1 -C 3 )alkyl]-amino, â€”C(O)â€”NH 2 , â€”C(O)OtBu, (C 1 -C 4 )alkoxy-(C 1 -C 2 )alkyl, hydroxy-(C 1 -C 2 )alkyl or dimethylamino-(C 1 -C 2 )alkyl; and R 2 represents â€”COâ€”(C 1 -C 3 )alkyl, â€”CO-cyclopropyl, â€”CF 2 â€”(C 1 -C 3 )alkyl, â€”CHFâ€”(C 1 -C 3 )alkyl or â€”SO 2 â€”(C 1 -C 3 )alkyl; or a salt thereof.