Patent ID: 8729114

Claim:
A compound of the formula (I): wherein the ring is chosen from: each optionally substituted by C 1-3 alkyl; R 1 is C 1-7 alkyl, C 3-7 cycloalkyl, aryl, heterocyclyl or heteroaryl each optionally substituted by one or more R c ; R 2 is hydrogen or C 1-7 alkyl; or R 1 and R 2 taken together form a C 3-7 cycloalkyl or C 3-7 heterocyclyl ring optionally substituted by one or more halogen or C 1-7 alkyl; R 3 is —C(O)C 1-7 alkyl, —C(O)C 3-7 cycloalkyl, —C(O)aryl, —C(O)heteroaryl, —C(O)heterocyclyl, —C(O)NR a R b , —C(O)OR a , —CH(R f )-heteroaryl, —CH(R f )-aryl, —CH(R f )-heterocyclyl, aryl, C 3-7 cycloalkyl or heteroaryl, each ring is optionally substituted by one or more R d ; R 4 and R 5 are each independently hydrogen, C 1-7 alkyl, aryl, or heteroaryl, or R 4 and R 5 taken together may form a C 3-7 cycloalkyl or C 3-7 heterocyclyl ring each ring being optionally substituted by C 1-5 alkyl; R a , R b each independently are hydrogen, C 1-7 alkyl, aryl or heteroaryl, or may be taken together to form a saturated or unsaturated C 3-7 cycloalkyl or C 3-7 heterocyclyl ring; R c is C 1-7 alkyl, C 1-7 alkoxy, C 3-7 cycloalkyl, aryl, benzyl, halogen or —C(O)—O-benzyl; R d each is independently chosen from C 1-7 alkyl, C 1-7 alkoxy, C 1-7 acyl, —C(O)NR a R b , —NH—C(O)—C 1-7 alkyl, halogen, —CN, —S(O) m —R e , —NH—S(O) m —R e ; R e is chosen from C 1-7 alkyl and amino; R f each is independently chosen from hydrogen or C 1-7 alkyl; m is 0-2; wherein one or more hydrogens on any one or more of R 1 , R 2 , R 3 , R 2 , R 4 , R 5 , R a , R b R c , R d , R e , R f or may be replaced by a halogen or deuterium atom; with the proviso that when is (i), and neither R 1 nor R 2 is hydrogen, and R 3 is —C(O)C 1-7 alkyl, —C(O)C 3-7 cycloalkyl, —C(O)aryl, —C(O)heteroaryl, —C(O)heterocyclyl, —CH(R f )-heteroaryl, —CH(R f )-aryl, —CH(R f )-heterocyclyl, aryl, C 3-7 cycloalkyl or heteroaryl then R 4 and R 5 must either both be hydrogen or they must form a ring, or a pharmaceutically acceptable salt thereof.