Patent ID: 8344004

Claim:
A compound of formula I: wherein R1 is (C1-C6) alkyl, (C0-C6) alkylene(C3-C6) cycloalkyl, (C0-C6) alkylene-O-(C1-C6) alkyl, (C0-C6) alkylene-O-(C3-C6) cycloalkyl, (C0-C6) alkylene-(C6-C14)aryl, or (C0-C6) alkylene-(C5-C15) heteroaryl, wherein the alkyl, alkylene, aryl, heteroaryl and cycloalkyl are unsubstituted or mono-, di- or tri-substituted by F, Cl, Br, (C1-C6) alkyl, O—(C1-C6) alkyl, CF 3 , OCF 3 , CN, CO—(C1-C6) alkyl, COO(C1-C6) alkyl, CON((C0-C6) alkylene-H)(C0-C6) alkylene-H), or S(O) m (C1-C6) akyl; R2 and R3 are independently H, halogen, (C1-C6) alkyl, (C0-C4) alkylene-O-(C0-C4) alkylene-H, CN, COO(C1-C6) alkyl, CON((C0-C6) alkylene-H)((C0-C6) alkylene-H), or S(O) m (C1-C6) alkyl, wherein the alkyl and alkylene are unsubstituted or mono-, di- or tri-substituted by F; and R4, R5, R6 and R7 are independently H, (C1-C6) alkyl, (C0-C6) alkylene-(C3-C6) cycloalkyl, (C0-C6) alkylene-(C6-C14)aryl, (C0-C6) alkylene-(C5-C15) heteroaryl, (C0-C6) alkylene-(C3-C15) heterocycloalkyl, or (C0-C6) alkylene-(C3-C15) heterocycloalkenyl, wherein the alkyl, alkylene and cycloalkyl are unsubstituted or mono-, di- or tri-substituted by halogen, (C1-C6) alkyl, (C0-C6) alkylene-O-(C0-C6)-alkylene-H, CF 3 , OCF 3 , CN, CO-(C1-C6) alkyl, COO-(C1-C6) alkyl, CON((C0-C6) alkylene-H)((C0-C6) alkylene-H), or S(O) m (C1-C6) alkyl, and wherein the aryl, cycloalkyl, heterocycloalkyl, heterocycloalkenyl and heteroaryl are unsubstituted or mono-, di- or tri-substituted by halogen, CF3, (C1-C6) alkyl or (C0-C4) alkylene-O-(C0-C4) alkylene-H, and wherein at least one pair of R4 and R5, R6 and R7, R5 and R6, together with the C-atoms to which they are connected, or R6 together with the ortho C-atom of the aromatic ring, form a (C3-C9) cycloalkyl, a (C3-C9)-heterocycloalkyl or a (C3-C9)-heterocycloalkenyl, wherein the cycloalkyl, heterocycloalkyl and heterocycloalkenyl are unsubstituted or mono, di- or tri-substituted by halogen, CF3, (C1-C6) alkyl or (C0-C4) alkylene-O-(C0-C4) alkylene-H; m is 0,1 or 2; or a stereoisomer or enantiomer or a mixture in any ratio thereof, or a physiologically acceptable salt thereof, or a tautomer thereof.