Patent ID: 7785631

Claim:
A therapeutic composition in solid dose form comprising a bioactive material and a carbohydrate, wherein a) the bioactive material is a protein, b) the therapeutic composition is a powder comprising therapeutic particles having a particle size distribution suitable for pulmonary administration, c) the therapeutic particles are in a glassy state, d) the bioactive material and the carbohydrate are dispersed within the therapeutic particles of the powder, e) the carbohydrate is selected from the group consisting of monosaccharides, disaccharides and sugar alcohols, f) the therapeutic particles remain in the glassy state when stored at elevated temperature, wherein the elevated temperature is 60° C., g) the protein is distributed homogeneously and in solid solution in the carbohydrate, and h) the therapeutic particles have a mean particle size of 0.5 to 5 μm.