Patent ID: 7244846

Claim:
A compound of formula I wherein D is CN, R 1 is Het, unsubstituted or A-substituted cycloalkyl having from 3 to 7 carbon atoms, or unbranched alkyl having from 1 to 6 carbon atoms, with the proviso that at least one CH 2 group in the alkyl group has been replaced by an O atom, by a CH═CH group or by a C≡C group, or with the proviso that at least one hydrogen atom in the alkyl group has been replaced by Hal, OH, Ar, Het, cycloalkyl having from 3 to 10 carbon atoms, N(R 4 ) 2, CN, CON(R 4 ) 2, or NR 4 COOR 4 , R 2 is H, A or R 1 , with the proviso that, if R 1 is amino, hydroxyl or cyano, R 2 is H, or NR 1 R 2 together is a three- to 7-membered saturated heterocyclic ring, in which, in addition, 1 or 2 N and/or 1 or 2 S and/or 1 or 2 O atoms and/or one S(O) m group, which may be substituted by A, Hal, cycloalkyl having from 3 to 10 carbon atoms, OR 4 , N(R 4 ) 2 , CN, COOR 4 , CON(R 4 ) 2 , NR 4 COR 4 and/or carbonyl oxygen, may be present, R 3 is OH, OA or N(R 4 ) 2 , R 4 is H or A, A is unbranched or branched alkyl having from 1 to 6 carbon atoms, in which at least one CH 2 group may be replaced by an O or S atom or by a CH═CH group, or at least one H atom may be replaced by F, Ar is phenyl, naphthyl or biphenyl, each of which is unsubstituted or monosubstituted or polysubstituted by Hal, A, OR 4 , N(R 4 ) 2 , NO 2 , CN, COOR 4 , CON(R 4 ) 2 , NR 4 COR 4 , NR 4 CON(R 4 ) 2 , NR 4 SO 2 A, COR 4 , SO 2 NR 4 or S(O) m A, Het is a saturated, unsaturated or aromatic monocyclic or bicyclic heterocyclic radical having from 5 to 10 ring members, in which from 1 to 4 N and/or from 1 to 4 S and/or from 1 to 4 O atoms may be present, and the heterocyclic radical may be monosubstituted, disubstituted or trisubstituted by Hal, A, —[C(R 4 ) 2 ] o —Ar, —[C(R 4 ) 2 ] o -cycloalkyl, OR 4, N(R 4 ) 2 , NO 2 , CN, COOR 4 , CON(R 4 ) 2 , NR 4 COA, NR 4 CON(R 4 ) 2 , NR 4 SO 2 A, COR 4 , SO 2 NR 4 S(O) m A and/or carbonyl oxygen, Hal is F, Cl, Br or I, n is 4, m is 1 or 2, o is 0, 1, 2, 3 or 4, or a physiologically acceptable salt thereof or solvate thereof.