Patent ID: 8592467

Claim:
A compound of formula: wherein: m is 0 or 1; one of R 1 and R 2 is hydrogen, acyl, acyloxy, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxyimino, alkoxysulfonyl, alkyl, alkylcarbonyl, alkylsulfonyl, alkynyl, amido, carboxy, cyano, cycloalkyl, fluoroalkoxy, haloalkoxy, haloalkyl, halogen, hydroxy, hydroxyalkyl, mercapto, nitro, alkylthio, —NR A R B , (NR A R B )carbonyl, —SO 2 N(R 14a )(R 14b ), —N(R 14a )SO 2 (R 14b ), a group of the formula -L 2 -R 6 , or a group of the formula -L 3a -R 6a -L 3b -R 6b ; the other of R 1 and R 2 is selected from the group consisting of hydrogen, cyano, halogen, alkyl, cycloalkyl, fluoroalkyl, alkoxy, alkoxyalkyl, fluoroalkoxy, alkylthio, —SO 2 N(R 14a )(R 14b ), and —N(R 14a )SO 2 (R 14b ); R 3a and R 3b are each independently selected from the group consisting of hydrogen, cyano, halogen, alkyl, cycloalkyl, fluoroalkyl, alkoxy, alkoxyalkyl, fluoroalkoxy, alkylthio, —SO 2 N(R 14a )(R 14b ), and —N(R 14a )SO 2 (R 14b ); R 4 and R 5 are each independently selected from the group consisting of alkyl, fluoroalkyl, hydroxyalkyl, alkoxyalkyl, and cycloalkyl; or R 4 and R 5 taken together with the nitrogen atom to which each is attached form a non-aromatic ring; R 6 is aryl, heterocycle or heterocyclealkyl; R 6a is aryl or heterocycle; R 6b is aryl or heterocycle; L is a bond or alkylene; L 2 is a bond, —O—, alkylene, —C(═O)—, —S—, —SO 2 N(R 14a )—, —N(R 14a )SO 2- —, —C(O)N(R 14a )—, —N(R 14a )C(O)—, or —N(R 15 )—; L 3a and L 3b are each independently selected from the group consisting of a bond, —O—, alkylene, —C(═O)—, —S—, —SO 2 N(R 14a )—, —N(R 14a )SO 2- —, —C(O)N(R 14a )—, —N(R 14a )C(O)—, and —N(R 15 )—; R 10 is selected from the group consisting of hydrogen, cyano, fluoro, hydroxy, and alkyl; R 14a and R 14b are each independently selected at each occurrence from the group consisting of hydrogen, alkyl, and cycloalkyl; R 15 is selected from the group consisting of hydrogen, alkyl, acyl, alkoxycarbonyl, and (R 14a )(R 14b )NC(O)—; and R A and R B are independently selected at each occurrence from the group consisting of from hydrogen, alkyl, acyl, haloalkyl, alkoxycarbonyl, cycloalkyl, and formyl; wherein at least one atom of the compound is a radioactive atom or radioactive isotope.