Patent ID: 8685437

Claim:
A process for forming a self-supporting, edible film having a substantially uniform distribution of components comprising at least one anti-emetic compound, said film being dissolvable or disintegrable, comprising the steps of: (a) providing a wet matrix having a uniform distribution of edible components, said components comprising a water-soluble polymer component, an active component comprising at least one anti-emetic compound in the form of particles and water to form an edible matrix with a compositionally uniform distribution of said components; (b) deaerating said matrix by mixing to prevent cavitation of the matrix in a manner which pulls air into the matrix; (c) forming a wet film from said deaerated wet matrix by coating or casting the film; (d) drying said film within about 10 minutes or fewer, wherein said drying step further comprises: (i) rapidly forming a visco-elastic film having said anti-emetic particles uniformly distributed throughout within about the first 4.0 minutes by applying hot air currents at temperatures of about 60Â° C. to about 100Â° C. to said film to prevent flow migration and intermolecular forces from creating aggregates or conglomerates of said anti-emetic particles thereby maintaining the compositional uniform distribution of components; and (ii) further drying said visco-elastic film to form a self-supporting edible film having anti-emetic particles uniformly distributed throughout; and (e) dividing said self-supporting film into dosage forms of substantially equal dimensions, wherein each of said dosage forms is compositionally equal, and wherein said dosage forms are each dissolvable or disintegrable in liquid.