Patent ID: 7807188

Claim:
A physiologically compatible composition consisting of a plurality of hydrated synthetic cells in an effective amount to provide water in an effective concentration of about 65% to about 85% of the total composition to a skin surface, the hydrated synthetic cells dispersed in a lipid matrix in an effective amount to provide a minimum surface free energy of about 20 dynes/cm to the skin surface; wherein at least one lipid component of the lipid matrix is selected from the group consisting of cholesterol esters in a range of about 20% to about 35% of the lipid matrix, ceramides in a range of about 10% to about 20% of the lipid matrix, triglycerides in a range of about 10% to about 20% of the lipid matrix, cholesterol in a range of about 5% to about 10% of the lipid matrix, free fatty acids in a range of about 5% to about 10% of the lipid matrix, phospholipids in a range of about 5% to about 10% of the lipid matrix, wax esters in a range of about 2% to about 8% of the lipid matrix, squalene in a range of about 0.5% to about 5% of the lipid matrix, wax diesters in a range of about 0.5% to about 6% of the lipid matrix, and cholesterol sulfate in a range of about 0.1% to about 3% of the lipid matrix, the concentration of the at least one lipid component providing from about 5% to about 30% of lipid in the composition.