Patent ID: 8764791

Claim:
A method of treating an anorectal fistula of a human patient, the anorectal fistula having a tract extending from a primary opening positioned in the anorectum at the dentate line to a secondary opening, wherein the secondary opening is positioned outside the anorectum in the perianal skin, the method comprising inserting a plug from the anorectum into the primary opening of the tract so as to occlude said primary opening, wherein the plug comprises a taper between a first plug end and a second plug end, wherein the plug comprises bioremodelable material that promotes cellular invasion and ingrowth and reconstruction of host tissue within the plug, and wherein the bioremodelable material is selected from the group consisting of a cadaveric material from a human donor and a heterograft material from a non-human donor, and positioning the plug in the tract whereby the bioremodelable material extends along the fistula tract from the primary opening to the secondary opening and promotes cellular invasion and ingrowth and reconstruction of host tissue within the plug.