Patent ID: 7388027

Claim:
A compound according to formula I: or a pharmaceutically acceptable salt thereof, wherein R 1 is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, arylalkyl, substituted arylalkyl, CO 2 R 4 , CONR 4 R 4 , and CH 2 OR 4 ; R 2 is independently selected from the group consisting of H, alkyl, substituted alkyl, OR 3 , SR 3 , halo, NHR 3 , NHCOR 4 , NHCO 2 R 4 , NHCONR 4 R 4 and NHSO 2 R 4 ; R 2 ′ is independently selected from the group consisting of OR 3 , SR 3 , halo, NHR 3 , NHCOR 4 , NHCO 2 R 4 , NHCONR 4 R 4 and NHSO 2 R 4 ; R 3 is independently selected from the group consisting of H, alkyl, substituted alkyl, CHF 2 , CF 3 and COR 4 ; R 4 is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; R 5 is independently selected from the group consisting of H, OR 3 , CF 3 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl, wherein R 5 and R 5 taken together can form a double bond with O, S, NR 4 or CR 7 R 7 when is a single bond, it being understood that only one R 5 is present when is a double bond; W is CR 6 R 6 , SO, or SO 2 ; R 6 is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl, wherein at least one R 6 is H, or R 6 and R 6 taken together can form a double bond with O, S, NR 7 or CR 7 R 7 ; R 7 is independently selected from the group consisting of H, OR 4 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; G is selected from the group consisting of aryl, heterocyclo and heteroaryl, wherein said aryl, heterocyclo or heteroaryl is mono- or polycyclic, and is optionally substituted with one or more substituents selected from the group consisting of hydrogen, halo, CN, CF 3 , OR 4 , CO 2 R 4 , NR 4 R 4 , CONR 4 R 4 , CH 2 OR 4 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; and n is 1 or 2.