Patent ID: 6949581

Claim:
A water-soluble mono-PEGylated tetrapyrrole derivative selected from the group consisting of formula 1, 2, and 3: wherein Y is a residue of a functionalized aminopolyethylene glycol H—Y, wherein Y is selected from the group consisting of: wherein B is a ring having the structure: wherein: R 1 =—CH═CH 2 , —CH(OAlk)CH 3 , —CHO, —C(O)CH 3 , —CH 2 CH 3 , —CH(Alk)CH(COAlk) 2 , —CH 2 CH(COAlk) 2 , —CH(Alk)CH 2 COAlk, —CH(Alk)CH 2 CH(OH)CH 3 , and —CH 2 CH 2 CH(OH)CH 3 ; R 2 =—CH 3 , —CHO, —CH(OH)Alk, —CH═CHAlk, —CH 2 OH, and —CH 2 OAlk; R 3 =—OH, —OAlk, —NH-Alk; R 4 =—OH, —OAlk, —NH-Alk; R 5 =—OH, —OAlk, —NH-Alk; R 6 =H and —COOAlk; R 8 =H and -Alk; R 10 =—OH, —OAlk, —NH 2 , —NHAlk, —NHAcyl, —NAcyl 2 , —NR 12 R 13 , —COR 14 , —OCH 2 COR 14 ; R 11 =—CH 2 CONR 8 —, —NHCOO—; R 12 =H and -Alk; R 13 =H and -Alk; and R 14 =—OH, —OAlk, —NR 12 R 13 ; Wherein: m=2-12; n=8-500; and Alk=an alkyl substituent.