Patent ID: 8450346

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein Ar 1 is optionally substituted phenyl; Ar 2 is optionally substituted phenyl, pyridyl, pyrimidinyl, pyrazinyl or pyridazinyl; and Ar 3 is a divalent radical selected from the group consisting of optionally substituted phenylene and optionally substituted pyridinylene; wherein the term “optionally substituted” means substituted with at least one substituent selected from (C 1 -C 6 )alkyl, (C 1 -C 6 )fluoroalkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )fluoroalkoxy, (C 1 -C 6 )alkoxy-(C 1 -C 6 )alkyl, benzyloxy-(C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy-(C 1 -C 6 )alkoxy, benzyloxy-(C 1 -C 6 )alkoxy, hydroxy, hydroxy(C 1 -C 6 )alkyl, hydroxy(C 1 -C 6 )alkoxy, mercapto, mercapto(C 1 -C 6 )alkyl, (C 1 -C 6 )alkylthio, cyclopropyl, halo, nitro, nitrile, —COOH, tetrazolyl, —COOR A , —COR A , —SO 2 R A , —CONH 2 , —SO 2 NH 2 , —CONHR A , —SO 2 NHR A , —CONR A R B , —SO 2 NR A R B , —NH 2 , —NHR A , —NR A R B , —OCONH 2 , —OCONHR A , —OCONR A R B , —NHCOR A , —NHCOOR A , —NR B COOR A , —NHSO 2 OR A , —NR B SO 2 OR A , —NHCONH 2 , —NR A CONH 2 , —NHCONHR B , —NR A CONHR B , —NHCONR A R B , or —NR A CONR A R B wherein R A and R B are independently a (C 1 -C 4 )alkyl group, or R A and R B when attached to the same nitrogen may form, together with that nitrogen, a cyclic amino group.