Patent ID: 7718702

Claim:
A compound of the formula a prodrug thereof, or a pharmaceutically acceptable salt, or stereoisomer of the compound or of said prodrug; wherein: R 1 is H, alkyl, haloC 1 -C 6 alkyl, cycloalkyl, cycloalkylNH—, arylalkyl, heterocycloalkyl, heteroaryl, N(R 2 ) 2 , or NR 2 aryl, unsubstituted aryl or aryl substituted with one to three X; R 2 is the same or different in each occurrence and is independently selected from H or C 1 -C 6 alkyl; R 3 is H, C 1 -C 6 alkyl, Cl, F, CF 3 , OCF 2 H, OCF 3 , OH or C 1 -C 6 alkoxy; R 4 is heteroaryl, heterocycloalkyl, or heteroarylNH—, wherein said heteroaryl is optionally substituted with from one to three X; R 5 is H or C 1 -C 6 alkyl; R 6 is H or C 1 -C 6 alkyl; or R 5 and R 6 taken together with the carbon atom form a carbonyl group; L 1 is C 1 -C 6 alkylene, C 3 -C 6 alkenylene, L 2 is a covalent bond, C 1 -C 6 alkylene, X is the same or different, and is independently selected from H, halogen, CF 3 , CN, OCF 2 H, OCF 2 CF 3 , OCF 3 , OR 2 , C 1 -C 6 alkyl, cycloalkyl, cycloalkoxy, C 1 -C 6 alkoxy, alkoxyC 1 -C 6 alkoxy, O-cycloalkyl, cycloalkylamino, cycloalkylalkoxy, heteroalkyl, —OSO 2 R 2 , —COOR 2 , —CON(R 2 ) 2 , NHR 2 , arylNH—, N(R 2 ) 2 , or NR 2 aryl; Y is a covalent bond, Z is a covalent bond, Y, R 1 , Z and R 2 can be taken together with the nitrogen atom to form a heterocycloalkyl; with the proviso that if Y is a covalent bond, R 1 cannot form a N—N bond with the nitrogen atom; and n is an integer of 0 to 4.