Patent ID: 8858931

Claim:
A method of inducing an HLA-B7-restricted immune response against at least one hTERT epitope, comprising: administering to an animal a lentiviral vector comprising a polynucleotide sequence that encodes a modified hTERT protein comprising the amino acid sequence of SEQ ID NO: 39; expressing the modified hTERT protein; and inducing an HLA-B7-restricted immune response against at least one hTERT epitope selected from: SEQ ID NO: 6 a. MPRAPRCRA (p1), SEQ ID NO: 7 b. APRCRAVRSL (p4), SEQ ID NO: 8 c. APSFRQVSCL (p68), SEQ ID NO: 9 d. RPAEEATSL (p277), SEQ ID NO: 10 e. RPSFLLSSL (p342), SEQ ID NO: 11 f. RPSLTGARRL (p351).