Patent ID: 8722700

Claim:
A method for administering a parenteral CCI-779 formulation to a subject in need thereof, said method comprising: (i) mixing CCI-779 with about 15 to about 60% w/v of dehydrated ethanol, about 0.01 to about 0.1% of d,1-α-tocopherol, about 0.001 to about 0.005% w/v of citric acid, and about 15 to about 60% w/v of propylene glycol to provide a cosolvent concentrate comprising about 1 to about 25 mg/mL of CCI-779; (ii) mixing about 15 to about 60% w/v of polysorbate 80, about 15 to 60% w/v of polyethylene glycol 400, and about 15 to about 60% w/v of dehydrated ethanol to provide a diluent; (iii) mixing said cosolvent concentrate and said diluent; and (iv) administering the product of step (iii) to said subject.