Patent ID: 7092748

Claim:
Method for the Tomography of the Primary Electric Current (TPEC) of the brain (TPECc) and of the heart (TPECk) comprising the following steps of: pre-processing of a plurality of signals recorded from a subject for the elimination of artifacts and of non-physiological frequency components; conversion of a plurality of coordinates of sensors to a reference system of a respective head or torso by means of the application of a visco-elastic deformation, that puts into correspondence the coordinates of a plurality of external anatomical markers of the subject with those of a structural image stored in a computing unit (CU); calculation of respective electric Kernel and magnetic Kernel linear operators that predict the o(t) that would be produced in the subject by the presence of the PEC j(t) in any part of the brain or heart; calculation of the TPEC by means of Bayesian Hierarchical Estimation Procedure that determines the primary electric current j(t) of the brain or heart using structural information obtained from an anatomical atlas, metabolic information obtained from functional images, and an assumption that the solution belongs to a space of Besov space of given smoothness or determined by a norm in a Megadictionary; calculation of descriptive parameters either on the basis of the observations o(t) directly, or of the j(t); calculation of a probability that all or some of the DP are similar to those of a given test group; and performing the step wherein the obtained TPECc is coded by means of a pseudocolor scale and is overlaid on the anatomical atlas, a scale being fitted according to the probability previously calculated, whereby only statistically significant anatomical sites are highlighted.