Patent ID: 7820823

Claim:
Compounds of Formula (I): wherein, (a) A is a group of the formula —V—W—, V being a group of the formula O, S, SO, or SO 2 , W being a heterocycloalkyl group with 4 to 7 ring atoms or a alkylheterocycloalkyl group with 4 to 7 ring atoms and 1 to 4 carbon atoms in the alkyl chain, heteroatoms of the heterocycloalkyl group or the alkylheterocycloalkyl group consisting of 1 N, W being optionally substituted by at least one substituent selected from the group consisting of F, Cl, Br, OH, NH 2 , SH, N 3 , NO 2 , an alkyl group, and a heteroalkyl group; (b) X is CR5; (c) Y is CR6 or N; (d) U is F or Cl; (e) n is 0 or 1; (f) R1 is H, F, Cl, Br, I, OH, NH 2 , an alkyl group or a heteroalkyl group; (g) R2 is H, F or Cl; (h) R3 is an ethyl, a 2-propyl, a C3-C6 cycloalkyl, a phenyl or a pyridyl group wherein all these groups may be substituted by one, two or more fluorine atoms or amino groups; (i) R4 is a group of the formula —NHCOCH═CHAryl, —O-Hetero-aryl, —NHSO 2 Me, —NHCOOMe, —NHCS 2 Me, —NHCSNH 2 , —NHCSOMe or —NHCOMe; (j) R5 is H, F, Cl, OH, NH 2 , an alkyl group or a heteroalkyl group, or (k) R3 and R5 together form a bridge of the formula —O—CH 2 —N(Me)- or —O—CH 2 —CH(Me)-; and (l) R6 is H, F, Cl or OMe; or a pharmacologically acceptable salt, hydrate or formulation thereof.