Patent ID: 6849660

Claim:
A compound having the formula I: wherein: X is O or S; Y is CH; n is 0; one of R 1 and R 1′ is —C(O)NR 5 R 5′ , —C(O)—Q—NR 5 R 5′ , —CH 2 NR 5 R 5′ or —S(O) 2 NR 5 R 5′ and the other is R 3 ; one of R 2 and R 2′ is —NHC(O)R 6 or —NHS(O) 2 R 6 and the other is R 4 ; Q is an amino acid or peptide; R 3 is —NR 5 R 5′ ; R 4 is selected from the group consisting of H, halogen, hydroxyl, amino, carboxyl, alkyl, alkenyl, alkynyl, alkoxy, a carbocycle radical and a heterocycle radical; R 5 is selected from the group consisting of H and alkyl optionally substituted with an amino, hydroxyl or urea radical; R 5′ is H; and R 6 is selected from the group consisting of H; amino; alkyl, alkenyl or alkynyl, each optionally substituted with halogen, amino, amidinyl, guanidinyl, urea radical, carboxyl or carboxamide radical; a 5-16 member carbocycle radical or heterocycle radical; and a 5-16 member heterocycle-substituted alkyl or carbocycle-substituted alkyl, wherein said carbocycle radical and heterocycle radical are optionally substituted with halogen, OH, amino, alkyl, carboxyl, oxo or carboxamide radical.