Patent ID: 7618522

Claim:
A method of reducing interferences in an electrochemical sensor having a sample chamber with first and second working electrodes disposed in the chamber, the working electrodes including a reagent disposed thereon, the method comprising: contacting a sample of physiological fluid with the working electrodes and reagent, the physiological fluid including at least an analyte disposed therein; applying a first potential to the first working electrode to initiate a chemical reaction; applying a second potential to the second working electrode to initiate a chemical reaction, wherein said second potential is greater than the absolute value of said first potential; measuring a first current, at said first working electrode, which comprises an analyte current and an interfering compound current; measuring a second current, at said second working electrode, which comprises an analyte overpotential current and an interfering compound overpotential current, wherein said analyte overpotential current has a first directly proportional relationship to said analyte current, the first directly proportional relationship comprising X×A 1 =A 2 where X is said analyte voltage effect factor derived from calibration test data of the sensor, A 1 is said analyte current, and A 2 is said analyte overpotential current and, wherein said interfering compound overpotential current has a second directly proportional relationship to said interfering compound current, the second directly proportional relationship is Y×I 1 =I 2 where Y is said interfering compound voltage effect factor, I 1 is said interfering compound current, and I 2 is said interfering compound over potential current; and calculating a corrected current value representative of an analyte concentration of the physiological fluid using an equation which is a function of said first current, said second current, said first directly proportional relationship, and said second directly proportional relationship.