Patent ID: 7629376

Claim:
A compound selected from the group consisting of formula I and formula II, or a stereoisomer, an enantiomer, a racemate or a tautomer of said compound, or a pharmaceutically acceptable salt thereof, wherein X is S or S(O) n ; R 1 is H or C 1 -C 6 alkyl; R 2 is NR 5 R 6 ; R 3 is aryl or heterocycle; R 4 is C 1 -C 6 alkyl or halogen; R 5 is H or C 1 -C 6 alkyl; R 6 is H or C 1 -C 6 alkyl; R 7 is CH 2 NR 8 R 9 wherein R 8 is H, C 1 -C 10 alkyl, C 3 -C 8 cycloalkyl, aryl, aryl(C 1 -C 6 alkyl), aryl(C 2 -C 6 alkenyl), diaryl(C 2 -C 6 alkenyl), heterocycle, heterocycle(C 1 -C 6 alkyl), heterocycle(C 2 -C 6 alkenyl), hydroxy(C 1 -C 6 alkyl), dihydroxy(C 2 -C 6 alkyl), acyl, C 1 -C 6 alkoxycarbonyl, aryl(C 1 -C 6 alkoxy)carbonyl, carbamoyl(C 1 -C 6 alkyl), or P; R 9 is H, C 1 -C 10 alkyl, heterocycle(C 1 -C 6 alkyl) or heterocycle(C 2 -C 6 alkenyl); or R 8 and R 9 together with the nitrogen to which they are attached form a heterocycle; and wherein P is Gly, or L- or D-Ala, Val, Leu, Ile, Ser, Cys, Thr, Met, Pro, Phe, Tyr, Trp, His, Lys, Arg, Asp, Gly, Asn or Gln; m is 0, 1 or 2; and n is 1.