Patent ID: 8183238

Claim:
A compound of Formula X-I: wherein: A is CR 1 ; X is CR 2 ; Y is CR 3 ; Z is CR 4 ; R 1 is H, halo, alkyl, alkoxy, or cyclopropyl; R 2 , R 3 , and R 4 are independently H, halo, alkyl, aryl, aralkyl, heteroaryl, alkoxy, cycloalkyloxy, alkoxyaryl, aryloxy, aralkyloxy, heterocycloalkyloxy, heteroaryloxy, cycloalkyl, alkylaryloxy, alkylheterocycloalkyl, alkylheteroaryloxy, heterocycloalkyl, CN, CH 2 NR 7 R 8 , NR 7 R 8 , C(═O)NR 7 R 8 , SO 2 NR 7 R 8 , SO 2 R 7a , NR 7 SO 2 R 7a , or NR 7 C(═O)R 7a , wherein each of said alkyl, aryl, aralkyl, heteroaryl, alkoxy, cycloalkyloxy, alkoxyaryl, aryloxy, aralkyloxy, heterocycloalkyloxy, heteroaryloxy, cycloalkyl, alkylaryloxy, alkylheterocycloalkyl, alkylheteroaryloxy, and heterocycloalkyl may be substituted with one or more substituents selected from hydroxy, amino, halo, alkyl, haloalkyl, CN, alkoxy, haloalkoxy, alkylamino, and aminoalkyl; R 5 is C(═O)R 9 , C(═O)OR 9 , C(═O)NR 9a R 9b , or (CH 2 )R 10 ; R 6a and R 6b are independently H, methyl, halomethyl, fluoro, or methoxy; each R 7 and R 8 is independently H, alkyl, haloalkyl, aryl, or heteroaryl; each R 7a is independently alkyl, haloalkyl, aryl, or heteroaryl; R 9 is alkyl, aryl, heteroaryl, or cycloalkyl, wherein each of said alkyl, aryl, heteroaryl, and cycloalkyl may be substituted with one or more substituents selected from hydroxy, amino, halo, alkoxy, and aminoalkyl; each R 9a and R 9b is independently H, alkyl, aryl, heteroaryl, or cycloalkyl, wherein each of said alkyl, aryl, heteroaryl, and cycloalkyl may be substituted with one or more substituents selected from hydroxy, amino, halo, alkoxy, and aminoalkyl, or, R 9a and R 9b , together with the nitrogen atom to which they are attached, form a 5- or 6-membered N-containing heterocyclic ring; R 10 is R 11 is H, alkyl, aryl, heteroaryl, or cycloalkyl, wherein each of said alkyl, aryl, heteroaryl, and cycloalkyl may be substituted with one or more substituents selected from hydroxy, amino, halo, alkoxy, and aminoalkyl; or a pharmaceutically acceptable salt thereof.