Patent ID: 8747435

Claim:
A method for closing a blood vessel puncture site disposed at a distal end of a tissue tract, the method comprising: introducing a closure device through the tissue tract, wherein a bio-chemical agent region of the closure device is coated with at least one bio-chemical agent prior to being introduced through the tissue tract; deploying an expansible member at a distal end of the device within the blood vessel after the closure device, including the bio-chemical agent region, has been introduced through the tissue tract; and displacing a bio-chemical region sealing member disposed proximal the expansible member so as to both expose the bio-chemical agent coated on the bio-chemical agent region of the device and apply tension to the expansible member through a tensioning element of the closure device to seat the expansible member against a puncture site; and wherein the at least one bio-chemical agent hydrates into surrounding fluids to form a coagulum in the tissue tract, wherein the tensioning element is disposed proximal the expansible member and is disposed coaxially over and surrounding an inner shaft of the closure device so that the expansible member is seated against a puncture site.