Patent ID: 7700783

Claim:
A process for synthesizing a compound of formula I comprising contacting a compound of formula i with a compound of formula xx in the presence of a catalytically effective amount of a cross-coupling metal catalyst; wherein R 0 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, (CH 2 ) r (C 3-6 cycloalkyl), (CH 2 ) r (aryl) or (CH 2 ) r (heterocycle), wherein r is 0, 1, 2, 3, or 4; R 1 , R 2 , and R 3 are, independently, H or C 1 -C 10 alkyl; R 6 , R 7 , and R 8 are, independently, C 1 -C 10 alkyl; R 4 and R 9 are, independently, H or an acid labile hydroxyl protecting group; R 10 is hydrogen; R 25 is hydrogen or an oxidation labile hydroxyl protecting group; X 1 and X 2 are, independently, halogen; and J is R 11 and R 12 are each independently C 1 -C 10 alkyl; and R 14 and R 15 are, independently, H or an acid labile hydroxyl protecting group.