Patent ID: 8188080

Claim:
A method of treating cancer comprising administering to a patient in need of one or more compounds, or pharmaceutically acceptable salts thereof, having the formula: wherein A is phenyl or a heteroaryl or heterocyclic ring having from 5 to 10 ring atoms that can be further substituted by one or more R units; each R is independently chosen from: i) alkyl, alkenyl, or alkynyl; ii) aryl; iii) heterocyclic; or iv) heteroaryl; that can be further substituted by one or more organic radicals; L 1 is a direct bond or a unit containing from 1 to 3 atoms; X 1 and X 2 are each independently O, S, or NH; Y 1 is one or two carbon atoms, a carbon and a nitrogen atom, a nitrogen atom, —O—, or —S—, wherein any of the carbon or nitrogen atoms can be further substituted by one or more organic radicals; Y 2 is one or two carbon atoms, a carbon and a nitrogen atom, or a nitrogen atom, wherein any of the carbon or nitrogen atoms can be further substituted by one or more organic radicals, wherein Y 2 is not —CH— when Y 1 is —S—; L is a linking group containing 1 to 3 carbon atoms; and Z is a keto, sulfonic acid, sulfonamide, alkylsulphonamide, phosphonic acid, or phosphonic ester radical, wherein the cancer is breast cancer, cervical cancer, ovarian cancer, leukemia cancer, hepatic cancer, nephritic cancer, pancreatic cancer, brain cancer, or lung cancer.