Patent ID: 7828973

Claim:
A filtration cassette comprising: a plurality of porous membranes, each membrane having a front side, a back side and a perimeter; each membrane further having an over-molded non-porous thermoplastic frame that individually encapsulates said membrane around the entirety of said perimeter, wherein said over-molded non-porous frame has a plurality of openings that define at least one retentate port, at least one feed port and at least one filtrate port, and flow channel means proximate a perimeter of said frame for providing a mechanism by which the cassette is encapsulated and sealed in one step and allows plastic to run in and around each port on each layer thereby sealing each layer and port from one another and bonding the entire assembly together; and comprising an over-molded thermoplastic encapsulating jacket that penetrates said flow channel to seal said plurality of membranes.