Patent ID: 7915264

Claim:
A compound of formula (I) wherein R 1 and R 2 , together, are —NR 11 —X—NR 12 C(O)—, wherein X is C(O) or C(S), R 11 is hydrogen; C 1 -C 4 alkyl; C 1 -C 4 alkyl substituted by C(O)OC 1 -C 4 alkyl; or phenyl substituted by C 1 -C 4 alkyl; R 12 is hydrogen, NH 2 or phenyl substituted by C 1 -C 4 alkyl; R 3 is hydrogen; OH; CN; C 1 -C 6 alkyl; phenyl; or C(O)OC 1 -C 4 alkyl; R 4 is CN; phenyl; phenyl substituted by OH, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl or C 1 -C 6 alkoxy; benzyl; benzoyl substituted by OH; R 5 is C 1 -C 6 alkyl; C 1 -C 6 alkyl substituted by halobenzyl; C 3 -C 6 cycloalkyl; phenyl; or pyridinyl; with the proviso that R 1 and R 2 together are not —NH—C(O)—NH—C(O)— when R 3 is phenyl, R 4 is —CN, and R 5 is —CH 3 ; in free base or acid addition salt form.