Patent ID: 8790874

Claim:
A device for investigation of a substantially tubular biological flow conduit comprising: a base having formed: therein a loading inlet for loading the flow conduit into the device; a main channel for receiving the flow conduit from the loading inlet, the main channel having a flow path along a first directional axis; a culture chamber in the main channel at least two fixation lines fluidly connected to the main channel for providing fixation of the flow conduit at at least two fixation locations along the length of the flow conduit within the culture chamber so that when fixed the flow conduit is substantially longitudinally aligned with the flow path along the first directional axis; the main channel having a perfusion inlet and a perfusion outlet, one of which is located before the at least two fixation lines along the flow path along the first directional axis and the other of which is located after the at least two fixation lines along the flow path along the first directional axis; and a superfusion channel fluidly connected to the main channel between the fixation locations, the superfusion channel having a flow path along a second directional axis at the point of connection to the main channel.