Patent ID: 8658172

Claim:
A method of treating human metastatic breast cancer in a subject said method comprising administering to a human an anti-EpCAM antibody comprising SEQ ID Nos. 3, 4, 5, 6, 7 and 8, wherein said subject exhibits high EpCAM expression showing a total immunostaining score for EpCAM of greater than 4, wherein said antibody is administered as at least one loading dose of 2 mg/kg body weight followed by multiple maintenance doses, each maintenance dose being 2 mg/kg body weight, wherein each loading dose is administered every week and each maintenance dose is administered every second week, wherein one loading dose is administered at the beginning of each of therapy weeks 1, 2 and 3 followed by 11 maintenance doses, and one maintenance dose is administered at the beginning of each of therapy weeks 4, 6, 8, 10, 12, 14, 16, 18, 20, 22 and 24.