Patent ID: 7709472

Claim:
A compound of formula (I) wherein: Z 1 and Z 4 are N; Z 2 , Z 3 , Z 5 , and Z 6 are each CR 1a ; A is CH 2 ; W 1 , W 2 , and W 4 are each CH 2 ; W 3 is a bond; B is a bond; R 1a is independently at each occurrence H or halo; R 1 is unsubstituted C (1-6) -alkoxy; R 6 , R 7 , R 8 , and R 11 are each H; R 12 is UR 13 ; where R 13 is 4H-pyrido[3,2-b][1,4]thiazin-3-oxo-6-yl, 4H-pyrido[3.2-b][1,4]oxazin-3-oxo-6-yl, or 2,3-dihydro-[1,4]dioxino[2,3-c]-pyridin-6-yl; U is CH 2 ; C(═O); or SO 2 ; or a pharmaceutically acceptable salt thereof.