Patent ID: 8481533

Claim:
A method of slowing progression of cancer and/or ameliorating one or more symptoms of cancer in a subject with cancer, comprising administering to a subject an effective amount of a compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof, wherein: R a is —F, methoxy, methyl or ethyl; R 4 is —H, methyl, ethyl, 2-methoxyethyl or —CH 2 CONH 2 ; and R 6 is —C═C-(optionally substituted phenyl); wherein the cancer is selected from the group consisting of lung cancer, breast cancer, colon cancer, neuroblastoma, prostate cancer, melanoma, glioblastoma multiforme, ovarian cancer, lymphoma, leukemia, osteosarcoma, germinoma, glioma, fibrosarcoma, gastrointestinal sarcoma, fibrous histiocytoma, round cell sarcoma, synovial sarcoma, cervical cancer, anogenital cancer, head and neck cancer, and oropharyngeal cancer.