Patent ID: 7250438

Claim:
A compound having the structure of Formula (I) and acid-addition salts and pro-drug esters thereof: wherein R 3 , R 4 , R 5 , and R 6 are each separately selected from the group consisting of hydrogen atom, halogen atom, mono-substituted, poly-substituted or unsubstituted variants of the following residues: saturated C 1 –C 10 alkyl, unsaturated C 2 –C 10 alkenyl or C 2 –C 10 alkynyl, cycloalkyl, cycloalkenyl, and hydroxy, or are separately absent when necessary to accommodate double bonds; Y has the following structure: R 1 , R 2 , and R 8 are each separately selected from the group consisting of a hydrogen atom, halogen atom, mono-substituted, poly-substituted or unsubstituted variants of the following residues: saturated C 1 –C 10 alkyl, unsaturated C 2 –C 10 alkenyl or C 2 –C 10 alkynyl, cycloalkyl, cycloalkenyl, and hydroxy; R 7 and R 9 are each separately selected from the group consisting of hydrogen atom, mono-substituted, poly-substituted or unsubstituted variants of the following residues: saturated C 1 –C 10 alkyl, unsaturated C 2 –C 10 alkenyl or C 2 –C 10 alkynyl, cycloalkyl, and cycloalkenyl; Q is an optionally substituted O or S; Z is NO 2 ; n is an integer from 0 to 10; any bond represented by a dashed and solid line represents a bond selected from the group consisting of a carbon-carbon single bond and a carbon-carbon double bond; when n is greater than 1, each unit n is bonded to any adjacent units n via carbon-carbon single bonds or carbon-carbon double bonds; and any carbon-carbon double bond has a configuration selected from the group consisting of cis and trans.