Patent ID: 8735623

Claim:
A method for preparation of amides of creatine, comprising the steps of: treatment of Creatine by p-Toluenesulfonic acid in an organic solvent thereby obtaining a complex; wherein said organic solvent is one of the following: Dimethylacetamide, or N-Methylpyrrolidone, or Dimethylsulfoxide, or N,N-Dimethylformamide; interaction of said complex with amino acid derivatives containing a primary or a secondary amino group in the presence of a condensation agent and a consequently introduced base soluble in organic solvents in a quantity providing the binding of evolved acid, wherein said condensation agent is represented by one of the following: dicyclohexylcarbodiimide, diisopropylcarbodiimide, iso-Butylchloroformate, and Ethylchloroformate; wherein said base is one of the following: N-methylmorpholine, triethylamine, and diisopropylethylamine.