Patent ID: 7868175

Claim:
A compound of formula I: wherein: a is 0 or 1; R 1 is halo; b is 0 or 1; R 2 is halo; A is selected from: where m is 0 or 1; s is 0, 1 or 2; t is 0, 1 or 2; R 4 is hydrogen or (1-4C)alkyl; and Ar 1 represents a (3-5C)heteroarylene group selected from pyrrole, imidazole, thiazole, oxazole, furan, thiophene, pyrazole, isoxazole, isothiazole, pyridine, pyrazine, pyridazine and pyrimidine; n is 1 or 2; R 7 is selected from hydrogen, —OH, -(1-4C)alkyleneOH, —NR 7a R 7b , —C(O)NR 7c R 7d , and —CH 2 C(O)NR 7c R 7d , where R 7a , R 7b , and R 7c are independently selected from hydrogen, (1-4C)alkyl, hydroxy, (1-4C)alkoxy, (1-4C)alkyleneOR 7e , (3-6C)cycloalkyl, phenyl optionally substituted with hydroxy, and (1-4C)alkyleneC(O)NR 7f R 7g ; and R 7d is selected from hydroxy, (1-4C)alkoxy, (1-4C)alkyleneOR 7h , (3-6C)cycloalkyl, phenyl optionally substituted with hydroxy, and (1-4C)alkyleneC(O)NR 7i R 7j ; where said (3-6C)cycloalkyl is unsubstituted or substituted with 1 or 2 (1-6C)alkyl or —NR 7k R 7l groups, and where each of R 7e , R 7f , R 7g , R 7h , R 7i , R 7j , R 7k , and R 7l is independently hydrogen or (1-4C)alkyl; or R 7c is taken together with R 7d to form a 3-7 membered ring, optionally substituted with hydroxyl; wherein each alkyl and alkoxy group in R 7a-l is optionally substituted with 1 to 5 fluoro substituents; or a pharmaceutically acceptable salt or stereoisomer thereof.