Patent ID: 7741480

Claim:
A process for the preparation of 5-aminomethyl substituted oxazolidinones of formula I: wherein X is O, S, SO or SO 2 ; R 1 is H, CH 3 or CN; R 2 is independently H, F or Cl; R 3 is H or CH 3 ; n is 0, 1 or 2; which comprises: converting the chlorine atom of the chloromethyl oxazolidinone compound of formula V: wherein X is O, S, SO or SO 2 ; R 1 is H, CH 3 or CN; R 2 is independently H, F or Cl; R 3 is H or CH 3 ; n is 0, 1 or 2; to azide using an azide source selected from the group consisting of sodium azide and potassium azide to prepare an azide compound of formula VI: wherein R1, R3, X, R2 and n are as defined in formula I; and hydrogenating the azide compound using a palladium/carbon catalyst to provide the compounds of formula I.