Patent ID: 7307073

Claim:
A compound of the formula I wherein X represents CO or SO 2 ; R 1 , R 2 , R 3 and R 4 are independently selected from H, (C 1,4 )alkyl, (C 1-4 )alkyloxy, (C 1-4 )alkyloxy(C 1-4 )alkyl, CF 3 , halogen, nitro, cyano, NR 8 R 9 , NR 8 COR 10 , and CONR 8 R 9 ; R 5 , R 6 and R 7 are independently H or (C 1-4 )alkyl; R 8 and R 9 are independently H or (C 1-4 )alkyl; or R 8 and R 9 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR 11 ; R 10 is (C 1-4 )alkyl; R 11 is (C 1-4 )alkyl; A is a C 2-5 alkylene wherein a carbon atom may be replaced by an oxygen, the ring being optionally substituted with 1-3 substituents selected from (C 1-4 )alkyl, (C 1-4 )alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof; with the proviso that the compounds of formula I wherein X is CO; each of R 1 -R 7 is H, and A represents (CH 2 ) 3 or (CH 2 ) 4 ; the compound of formula I wherein X is CO; R 1 is H; R 2 is methyl; each of R 3 -R 7 is H; and A represents (CH 2 ) 3 ; the compound of formula I wherein X is CO; R 1 and R 2 are H; R 3 is methyl; each of R 4 -R 7 is H; and A represents (CH 2 ) 3 ; the compound of formula I wherein X is CO; each of R 1 -R 3 is H; R 4 is methyl; each of R 5 -R 7 is H; and A represents (CH 2 ) 3 ; and the compound of formula I wherein X is CO; each of R 1 -R 4 is H; R 5 is methyl; R 6 and R 7 are H; and A represents (CH 2 ) 3 ; are excluded.