Patent ID: 8759373

Claim:
A method of treating anemia, the method comprising administering to a patient in need thereof a therapeutically effective amount of a pharmaceutical composition comprising one or more compounds represented by formula I: wherein: R is selected from the group consisting of hydrogen, alkyl, and substituted alkyl; R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of hydrogen, halo, cyano, hydroxyl, alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, amino, substituted amino, —OR 7 , —SR 7 , —SOR 7 , and —SO 2 R 7 wherein R 7 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl; R 5 and R 6 are independently selected from the group consisting of hydrogen or C 1-3 alkyl; or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof; or an ester or amide of the carboxylic acid moiety on the glycine or alanine-based substituent of the cyanoisoquinoline ring, and a pharmaceutically acceptable excipient.