Patent ID: 7951783

Claim:
An isolated polynucleotide encoding a T cell receptor (TCR) alpha chain portion containing three alpha complementarity determining regions (CDRs): CDR1α: SSYSPS (SEQ ID NO: 2); CDR2α: YTSAATL (SEQ ID NO: 3); and CDR3α: SPFSGGGADGLT (SEQ ID NO: 5), wherein a TCR molecule containing the TCR alpha chain portion encoded by said polynucleotide and a TCR beta chain portion containing three beta CDRs: CDR1β: DFQATT (SEQ ID NO: 6); CDR2β: SNEGSKA (SEQ ID NO: 7); and CDR3β: RDGGEGSETQY (SEQ ID NO: 9) has affinity for an HLA-A2/RMFPNAPYL (SEQ ID NO: 1) complex.