Patent ID: 7008958

Claim:
A compound having the formula (I), or a pharmaceutically-acceptable salt, hydrate, or prodrug thereof, wherein: R 1 is selected from optionally-substituted aryl, heteroaryl, arylkyl, and heteroarylalkyl; R 2 is selected from hydrogen, halogen, cyano, alkyl, substituted alkyl, —C(═O)R 6 , —CO 2 R 6 , —S(═O)R 7 , —SO 2 R 7 , —SO 3 R 7 , —OR 6 , —SR 6 , —NR 6 R 7 , —C(═O)NR 6 R 7 , —NR 6 C(═O)R 7 , NR 6 CO 2 R 7 , —NR 6 SO 2 R 7 , —SO 2 NR 6 R 7 , cycloalkyl, aryl, heterocyclo and heteroaryl, or alternatively, R 1 and R 2 taken together from an optionally-substituted fused (C 5-6 )carbocyclic ring or five-to-six membered heterocyclo ring; R 3 is alkyl, substituted alkyl, alkoxy, haloalkoxy, or halogen; R 4 and R 5 are independently selected from alkyl, substituted alkyl, halogen, cyano, and —OR 9 ; R 6 and R 7 are selected from hydrogen, alkyl, substituted alkyl, cycloalkyl, aryl, heterocyclo, and heteroaryl, except R 7 is not hydrogen when attached to a sulfonyl group as in —S(═O)R 7 , —SO 2 R 7 , and —SO 3 R 7 ; R 9 is hydrogen, C 1-6 alkyl, substituted C 1-6 alkyl, cycloalkyl, aryl, heterocyclo, or heteroaryl; and m and n are 0, 1 or 2.