Patent ID: 7745428

Claim:
A compound of formula (I): wherein: R 1 is selected from halo, amino, C 1-3 alkyl, C 1-3 alkoxy, N—(C 1-3 alkyl)amino, N,N—(C 1-3 alkyl) 2 amino and a nitrogen linked 4-7 membered saturated ring which optionally contains an additional nitrogen, oxygen or sulphur atom; m is 0-4; wherein the values of R 1 may be the same or different; R 2 is selected from hydrogen, halo, amino, C 1-3 alkyl and C 1-3 alkoxy; R 3 is hydrogen or halo; R 4 is hydrogen, ethynyl, halo, cyano, hydroxy, amino, mesyl, trifluoromethyl, trifluoromethoxy, methyl, ethyl or methoxy; Ring A is a nitrogen linked 4-7 membered saturated ring which optionally contains an additional nitrogen, oxygen or sulphur atom; wherein if said ring contains an additional nitrogen atom that nitrogen may be optionally substituted by R 6 ; R 5 is a substituent on carbon and is selected from halo, cyano, hydroxy, trifluoromethoxy, amino, carboxy, carbamoyl, sulphamoyl, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 alkanoyl, N—(C 1-6 alkyl)carbamoyl, N,N—(C 1-6 alkyl) 2 carbamoyl, C 1-6 alkylS(O) a wherein a is 0 to 2, C 1-6 alkoxycarbonyl, N—(C 1-6 alkyl)sulphamoyl and N,N—(C 1-6 alkyl) 2 sulphamoyl; wherein R 5 independently may be optionally substituted on carbon by one or more R 7 ; or R 5 is —NHR 8 , —NR 9 R 10 or —O—R 11 ; n is 0-4; wherein the values of R 5 may be the same or different; R 6 is selected from C 1-6 alkyl, C 1-6 alkanoyl, C 1-6 alkylsulphonyl, C 1-6 alkoxycarbonyl, carbamoyl, N—(C 1-6 alkyl)carbamoyl and N,N—(C 1-6 alkyl)carbamoyl; wherein R 6 may be optionally substituted on carbon by one or more R 12 ; R 8 , R 9 , R 10 R 11 are independently selected from C 1-4 alkyl, C 1-4 alkanoyl, C 1-4 alkylsulphonyl, C 2-4 alkenylsulphonyl, C 2-4 alkynylsulphonyl, C 1-4 alkoxycarbonyl, carbamoyl, N—(C 1-4 alkyl)carbamoyl, N,N—(C 1-4 alkyl)carbamoyl, carbocyclyl and heterocyclyl; wherein R 8 , R 9 , R 10 and R 11 may be independently optionally substituted on carbon by a group selected from R 13 ; and wherein if said heterocyclyl contains an —NH— moiety that nitrogen may be optionally substituted by R 14 ; R 13 is selected from halo, cyano, hydroxy, amino, trifluoromethyl, trifluoromethoxy, C 1-3 alkyl and C 1-3 alkoxy; R 14 is selected from C 1-3 alkyl, C 1-3 alkanoyl, C 1-3 alkylsulphonyl, C 1-3 alkoxycarbonyl, carbamoyl, N—(C 1-3 alkyl)carbamoyl and N,N—(C 1-3 alkyl)carbamoyl; and R 7 and R 12 are independently selected from halo, cyano, hydroxy, trifluoromethoxy, trifluoromethyl, amino, carboxy, carbamoyl, sulphamoyl, methyl, ethyl, methoxy, ethoxy, acetyl, acetoxy, methylamino, ethylamino, dimethylamino, diethylamino, N-methyl-N-ethylamino, acetylamino, N-methylcarbamoyl, N-ethylcarbamoyl, N,N-dimethylcarbamoyl, N,N-diethylcarbamoyl, N-methyl-N-ethylcarbamoyl, methylthio, ethylthio, methylsulphinyl, ethylsulphinyl, mesyl, ethylsulphonyl, methoxycarbonyl, ethoxycarbonyl, N-methylsulphamoyl, N-ethylsulphamoyl, N,N-dimethylsulphamoyl, N,N-diethylsulphamoyl and N-methyl-N-ethylsulphamoyl; or a pharmaceutically acceptable salt thereof.