Patent ID: 7572782

Claim:
A method for stimulating bone regeneration in a patient, comprising: administering to the patient an effective amount of a pharmaceutical formulation comprising: peroxidic species or reaction products resulting from oxidation of menthol or an alkene by an oxygen-containing oxidizing agent, wherein the oxygen-containing oxidizing agent is selected from the group consisting of singlet oxygen, oxygen in its triplet state, superoxide anion, periodate, hydroxyl radical, hydrogen peroxide, alkyl peroxide, carbamyl peroxide, benzoyl peroxide, oxygen bound to a transition element, and ozone, and wherein the alkene is selected from the group consisting of terpineol, citronellol, nerol, linalool, phytol, geraniol, perillyl alcohol, menthol, geranylgeraniol and farnesol, and wherein the peroxidic species or reaction products resulting from oxidation of menthol or the alkene is from about 0.001% to about 30% by weight of the pharmaceutical formulation; a penetrating solvent, wherein the penetrating solvent is selected from the group consisting of dimethylsulfoxide, sterol, lecithin, propylene glycol, and methylsulfonylmethane, and wherein the penetrating solvent is from about 50% to about 99% by weight of the pharmaceutical formulation; a dye containing a chelated divalent or trivalent metal, wherein the dye is selected from the group consisting of porphyrin, rose bengal, chlorophyllin, hemin, corrins, texaphrin, methylene blue, hematoxylin, eosin, erythrosin, lactoflavin, anthracene dye, hypericin, methylcholanthrene, neutral red, phthalocyanine, fluorescein, eumelanin, and pheomelanin, and wherein the dye is from about 0.1% to about 30% by weight of the pharmaceutical formulation; and an aromatic redox compound, wherein the redox compound is selected from the group consisting of substituted or unsubstituted benzoquinone, naphthoquinone, and anthroquinone, and wherein the aromatic redox compound is from about 0.01% to about 20% by weight of the pharmaceutical formulation.