Patent ID: 6932960

Claim:
A radiopharmaceutical of the formula: M(C h ) n , or pharmaceutically acceptable salt thereof, wherein: M is a radionuclide selected from: 64 Cu, 67 Cu, 67 Ga, 68 Ga, 99m Tc, 111 In, 90 Y, 149 Pr, 153 Sm, 159 Gd, 166 Ho, 169 Yb, 177 Lu, 86 Re, and 188 Re; C h is an N-substituted 3-hydroxy-4-pyridinone compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is selected from the group: CH 2 , C(O), C(S), P(O)R 3 R 4 , SO 2 , C(═NH)NH, C(O)NH, and C(S)NH; R 1 and R 2 are independently selected from: H, C 1 --C 10 alkyl substituted with 0-5 R 5 , C 2 -C 10 alkenyl substituted with 0-5 R 5 , aryl substituted with 0-3 R 5 , and heteroaryl substituted with 0-3 R 5 ; R 3 and R 4 are independently selected from: C 1 -C 10 alkyl substituted with 0-5 R 5 , C 2 -C 10 alkenyl substituted with 0-5 R 5 , aryl substituted with 0-3 R 5 , and heteroaryl substituted with 0-3 R 5 , or R 3 and R 4 may be taken together to form a C 5 -C 7 cyclic alkyl group optionally interrupted with O or NR 6 ; R 5 is selected from: OH, C(═O)R 6 , C(═O)OR 6 , C(═O)NR 6 R 7 , PO(OR 6 )(OR 7 ), and S(O) 2 OR 6 ; R 6 and R 7 are independently selected from: H, C 1 -C 10 alkyl, and aryl; and n is 2 or 3.