Patent ID: 7473683

Claim:
A nucleoside analog comprising a halogenated base of the structure: where R 1 is a sugar moiety; R 2 is H, CH 3 , an imaging moiety selected from 11 CH 3 , 13 N, 15 O, 18 F, 123 I, 124 I, 125 I, 128 I, 111 In, 67 Ga and 99m Tc or a cytotoxic moiety selected from 123 I, 125 I, 131 I, 90 Y, 211 At, 67 Cu, 186 Re, 188 Re, 212 Pb, and 212 Bi; and X 1 and X 2 are a combination selected from 2,4-dichloro; 2,4-dibromo; 2-chloro,4-bromo; 2-bromo,4-chloro; 2-bromo,4-fluoro; and 2-fluoro,4-bromo.