Patent ID: 8287860

Claim:
A pharmaceutical composition for passive immunization comprising polyclonal antibodies or antigen binding fragments thereof, wherein the polyclonal antibodies or the antigen binding fragments thereof obtained from animals immunized with a mixture from the following antigens of genus Loxosceles: sphingomyelinase D recombinant Loxosceles boneti (SMDrLb1) of SEQ ID NO: 11; sphingomyelinase D recombinant Loxosceles reclusa (SMDrLr1) of SEQ ID NO: 13; sphingomyelinase D recombinant Loxosceles laeta (SMDrLl1) of SEQ ID NO: 19; and sphingomyelinase D recombinant Loxosceles laeta (SMDrLl2) of SEQ ID NO: 21.