Patent ID: 8753627

Claim:
A pharmaceutical composition comprising a pharmaceutically acceptable excipient and an isolated antibody or antigen binding fragment thereof, comprising: a. a light chain variable domain (VL) comprising: i. a CDR1 sequence of the amino acid sequence set forth in SEQ ID NO:11; ii. a CDR2 sequence of the amino acid sequence set forth in SEQ ID NO:12; and iii. a CDR3 sequence of the amino acid sequence set forth in SEQ ID NO:13; and b. a heavy chain variable domain (VH) comprising: i. a CDR1 sequence of the amino acid sequence set forth in SEQ ID NO:62; ii. a CDR2 sequence of the amino acid sequence set forth in SEQ ID NO:63; and iii. a CDR3 sequence of the amino acid sequence set forth in SEQ ID NO:64, wherein the antibody or antigen binding fragment thereof binds specifically to human activin A.