Patent ID: 6949646

Claim:
A compound of formula wherein A is —N═CR—CR═CR—; —CR═N—CR═CR—; —CR═CR—N═CR—; or —CR═CR—CR═N—; R 1 is selected from the group consisting of: -hydrogen; —C 1-20 alkyl or C 2-20 alkenyl that is unsubstituted or substituted by one or more substituents selected from the group consisting of: -aryl; -heteroaryl; -heterocyclyl; —O—C 1-20 alkyl, —O—(C 1-20 alkyl) 0-1 -aryl; —O—(C 1-20 alkyl) 0-1 -heteroaryl; —O—(C 1-20 alkyl) 0-1 -heterocyclyl; —C 1-20 alkoxycarbonyl; —S(O) 0-2 —C 1-20 alkyl; —S(O) 0-2 —(C 1-20 alkyl) 0-1 -aryl; —S(O) 0-2 —(C 1-20 alkyl) 0-1 -heteroaryl; —S(O) 0-2 —(C 1-20 alkyl) 0-1 -heterocyclyl; —N(R 3 ) 2 ; —N 3 ; oxo; -halogen; —NO 2 ; —OH; and —SH; and —C 1-20 alkyl-NR 3 —Q—X—R 4 or —C 2-20 alkenyl-NR 3 —Q—X—R 4 wherein Q is —CO— or —SO 2 —; X is a bond, —O— or —NR 3 — and R 4 is aryl; heteroaryl; heterocyclyl; or —C 1-20 alkyl or C 2-20 alkenyl that is unsubstituted or substituted by one or more substituents selected from the group consisting of: -aryl; -heteroaryl; -heterocyclyl; —O—C 1-20 alkyl, —O—(C 1-20 alkyl) 0-1 -aryl; —O—(C 1-20 alkyl) 0-1 -heteroaryl; —O—(C 1-20 alkyl) 0-1 -heterocyclyl; —C 1-20 alkoxycarbonyl; —S(O) 0-2 —C 1-20 alkyl; —S(O) 0-2 —(C 1-20 alkyl) 0-1 -aryl; —S(O) 0-2 —(C 1-20 alkyl) 0-1 -heteroaryl; —S(O) 0-2 —(C 1-20 alkyl) 0-1 -heterocyclyl; —N(R 3 ) 2 ; —NR 3 —CO—O—C 1-20 alkyl; —N 3 ; oxo; -halogen; —NO 2 ; —OH; and —SH; or R 4 is wherein Y is —N— or —CR—; R 2 is selected from the group consisting of: -hydrogen; —C 1-10 alkyl; —C 2-10 alkenyl; -aryl —C 1-10 alkyl —O—C 1-10 -alkyl; —C 1-10 alkyl-O—C 2-10 alkenyl; and —C 1-10 alkyl or C 2-10 alkenyl substituted by one or more substituents selected from the group consisting of: —OH; -halogen; —N(R 3 ) 2 ; —CO—N(R 3 ) 2 ; —CO—C 1-10 alkyl; —N 3 ; -aryl; -heteroaryl; -heterocyclyl; —CO-aryl; and —CO-heteroaryl; each R 3 is independently selected from the group consisting of hydrogen and C 1-10 alkyl; and each R is independently selected from the group consisting of hydrogen, C 1-10 alkyl, C 1-10 alkoxy, halogen and trifluoromethyl, or a pharmaceutically acceptable salt thereof.