Patent ID: 7034005

Claim:
A method for suppressing infection and/or proliferation of human immunodeficiency syndrome virus in a macrophage derived from a human monocyte, comprising treating said macrophage with an effective amount of a macrolide derivative, wherein the macrolide derivatives is 11-(1′-hydroxypropyl)-3-[2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl]oxy]-5-[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy]-2,4,6,8,11,14-hexamethyl-10,13-15-tri-oxatricyclo[9.2.1.1. 9.6 ]-pentadecane-1-one or 4,13-Dioxabicyclo[8.2.1]tridec-12-en-5-one, 7-[(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)oxy]-3-(1,2-dihydroxy-1-methylbutyl)-2,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy], and wherein the macrophage derived from human monocytes is an M type macrophage.