Patent ID: 8420689

Claim:
A method of treating pain associated with diabetic neuropathy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound of formula (IA): or an analog thereof, pharmaceutically acceptable salt thereof, pharmaceutically acceptable ester thereof, tautomer thereof, stereoisomer thereof, enantiomer thereof, or diastereomer thereof, wherein each occurrence of R is independently substituted or unsubstituted alkyl, substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl; R 1 is hydrogen; R 2 is substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heterocyclic group, substituted or unsubstituted heteroaryl group, substituted or unsubstituted heteroarylalkyl, or NR 3 R 4 ; or R 1 and R 2 may be joined together to form an optionally substituted piperidinyl R 3 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl or substituted or unsubstituted cycloalkyl and R 4 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted cycloalkyl; or R 3 and R 4 may be joined together to form an optionally substituted 3 to 7 membered saturated or unsaturated cyclic ring, which may optionally include at least two heteroatoms selected from O, NR 3 or S; p is 1; and A is wherein each of the dotted lines in A independently represents an optional bond, and each occurrence of R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , and R 14 is the same or different and selected from hydrogen, substituted or unsubstituted alkyl or substituted or unsubstituted aryl; with the proviso that the compound does not have the formula: wherein R 1 and R 2 are as defined above.