Patent ID: 8722352

Claim:
A method of testing a mammal for presence, progression or stage of non-septic hypovolemic shock, comprising: obtaining a blood sample from the mammal and removing a cellular fraction from the blood to so obtain a serum or plasma fraction; adding a substrate for trypsin to the serum or plasma fraction, and measuring a product formed from the substrate to thereby measure activity of the trypsin to obtain a test result; and using the test result, upon diagnosis of the mammal as having a shock condition, to ascertain at least one of presence, progression, and stage of non-septic hypovolemic shock in the mammal; wherein the step of using the test result comprises a step of correlating the test result with a corresponding test result of a healthy mammal, wherein an increased activity of the trypsin as compared to the healthy mammal is indicative of the at least one of the presence, progression, and stage of non-septic hypovolemic shock.