Patent ID: 6903121

Claim:
A pharmaceutical composition for the treatment of a malignant disease or condition in a mammal, said disease or condition being selected from the group consisting of breast cancer, colon cancer and leukemia, the composition comprising a pharmaceutically acceptable excipient and a therapeutically effective dose of a compound of the formula where X is S or O; R 1 is, independently, H or lower alkyl of 1 to 6 carbons; R 2 and R 3 are, independently, H, lower alkyl of 1 to 6 carbons, F, Cl, Br, I, alkoxy of 1 to 6 carbons, or fluoroalkoxy of 1 to 6 carbons; m is an integer 0 to 3; o is an integer 0 to 4; n is 0-5; Y is phenyl, naphthyl, or a heteroaryl group selected from a group consisting of pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl, pyrazinyl; oxazolyl, thiazolyl, or imidazolyl; and B is COOH, a pharmaceutically acceptable salt thereof, CONR 6 R 7 or COOR 8 where R 6 and R 7 , independently, are hydrogen or an alkyl group of 1 to 6 carbons and R 8 is alkyl of 1 to 6 carbons; said composition to be used in combination with interferon.