Patent ID: 8575116

Claim:
A method of protecting against atrophy of pancreatic islets, comprising: administering a pharmaceutical composition comprising: (a) an effective amount of a compound of formula (I) wherein R is H or COCH2COOH; m=3 or 4; n=0 or 1; o=2; and p=1 or 2, and (b) a pharmaceutically acceptable carrier; to a human who has any three of the following conditions: i) waist measurement of 40 inches or more for men and 35 inches or more for women; ii) triglyceride levels of 150 milligrams per deciliter (mg/dL) or above, or taking medication for elevated triglyceride levels; iii) HDL cholesterol level below 40 mg/dL for men and below 50 mg/dL for women, or taking medication for low HDL levels; and iv) blood pressure levels of 130/85 or above, or taking medication for elevated blood pressure levels.