Patent ID: 8795693

Claim:
A waterless composition comprising one or more active agents and a carrier for topical delivery of the one or more active agents suitable for stabilizing at least one of said one or more active agents, said carrier comprising: a) about 25% to about 98% of at least one polar solvent selected from the group consisting of a polyol, a polyethylene glycol, and combinations thereof; b) a modulating agent; c) about 0.01% to about 5% by weight of at least one polymeric agent; d) a surface active agent; and e) a foam adjuvant selected from the group consisting of a fatty alcohol having 15 or more carbons in its carbon chain, a fatty acid having 16 or more carbons in its carbon chain and mixtures of any two or more thereof; wherein the at least one active agent is chemically unstable in the carrier in the absence of a modulating agent; wherein the modulating agent is capable of and is selected to modulate or adjust the artificial pH of the carrier to an artificial pH or to provide an artificial pH buffering effect such that the chemical stability of the at least one active agent is increased as compared to its stability in the carrier without the modulating agent; and wherein if the waterless composition is packaged in an aerosol container and a liquefied or compressed gas propellant is added at a concentration of about 3% to about 25% by weight of the waterless composition, then the composition will be capable upon release from the aerosol container to expand to form a breakable foam that collapses upon application of shear force.