Patent ID: 8598194

Claim:
A compound of formula I or salt thereof wherein: R 1 is selected from C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, —(CH 2 ) n C 3-7 cycloalkyl, —(CH 2 ) n C 4-7 cycloalkenyl, —(CH 2 ) n aryl, —(CH 2 ) n aryl C 1-12 alkyl, —(CH 2 ) n arylC 2-12 alkenyl, —(CH 2 ) n arylC 2-12 alkynyl, and —(CH 2 ) n heterocyclyl; n is 0-6; and said alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl and heterocyclyl groups are optionally substituted; R 2 is selected from H, O, —CH 2 R 3 , —C(═Y)R 3 , —C(═Y)OR 3 , —C(═Y)N(R 4 )R 3 , —C(═Y)CH 2 N(R 4 )R 3 , —C(═Y)CH 2 SR 3 and —S(O) w R 5 , where R 3 is selected from hydrogen, C 1-12 alkyl, C 2-12 alkenyl, C 2-12 alkynyl, —(CH 2 ) m C 3-7 cycloalkyl, —(CH 2 ) m C 4-7 cycloalkenyl, —(CH 2 ) m aryl, —(CH 2 ) m arylC 1-12 alkyl, —(CH 2 ) m arylC 2-12 alkenyl, —(CH 2 ) m arylC 2-12 alkynyl and —(CH 2 ) m heterocyclyl; and when R 2 is —CH 2 R 3 , or —C(═Y)R 3 , R 3 may also be selected from —S—R 5 and —O—R 5 ; m is 0-6; R 4 is hydrogen or C 1-6 alkyl; R 5 is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl, benzyl, aryl or heterocyclyl; w is 0, 1 or 2; and the alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl and heterocyclyl groups are optionally substituted; X is O and Y is selected from O, S and NR 6 , where R 6 is independently selected from hydrogen, C 1-6 alkyl, hydroxy and C 1-6 alkoxy; A together with the atoms to which it is attached forms an optionally substituted phenyl; B—C is —CH 2 CH 2 ; and D is —CH 2 , provided that when A together with the atoms to which it is attached forms an unsubstituted phenyl ring, and R 1 is unsubstituted phenyl, then R 2 is not H.