Patent ID: 8268817

Claim:
A chemical entity selected from compounds of Formula (I): wherein: n is 0, 1, 2, or 3; R 1 is —CF 3 ; —CN; —CHO; —C(O)C 1-4 alkyl unsubstituted or substituted with one, two, or three fluoro substituents; —CO 2 C 1-4 alkyl; —CO 2 H; —C(O)N(R a )R b ; —CH 2 NR a R b ; —SO 2 N(R c )R d ; —SC 1-4 alkyl; —SO 2 C 1-4 alkyl; —SO 2 CF 3 ; or halo; where R a and R b are each independently —H, —C 1-6 alkyl, or —C 3-6 cycloalkyl, or R a and R b taken together with the nitrogen to which they are attached form a saturated monocyclic heterocycloalkyl group, unsubstituted or substituted with —C 1-4 alkyl, —OH, —OC 1-4 alkyl, or halo; and R c and R d are each independently —H or —C 1-6 alkyl; and R 2 is —H; —C 1-6 alkyl; —C 3-6 cycloalkyl; —CF 3 ; —CN; —C(O)C 1-4 -alkyl optionally substituted with one, two, or three fluoro substituents; —CO 2 C 1-4 alkyl; —CO 2 H; —C(O)N(R f )R g ; —OH; —OC 1-6 alkyl; halo; —NO 2 ; —NR f R g ; —N(R f )COR g ; —N(R f )SO 2 R g ; —SO 2 N(R f )R g ; or —S(O) 0-2 R h ; where R f and R g are each independently —H, —C 1-6 alkyl, or —C 3-6 cycloalkyl; and R h is —C 1-4 alkyl unsubstituted or substituted with one, two, or three fluoro substituents; and pharmaceutically acceptable salts of compounds of Formula (I).