Patent ID: 8765775

Claim:
A compound of formula 1 wherein R 1 is hydrogen, R 2 is lower alkyl, arylsulfonyl, heteroarylsulfonyl, lower alkylsulfonyl, aminosulfonyl, lower alkylaminosulfonyl, arylcarbonyl, heteroarylcarbonyl, lower alkylcarbonyl, lower alkoxycarbonyl, aminocarbonyl, lower alkylaminocarbonyl or carboxy; R 3 is alkyl, hydroxy-lower alkyl, methoxy-lower alkyl, aryl-lower alkyl, or heteroaryl-lower alkyl; R 4 is para-fluoro or para-chloro; and R 5 is hydrogen; or wherein R 1 is hydrogen, R 2 is lower alkyl, arylsulfonyl, heteroarylsulfonyl, lower alkylsulfonyl, aminosulfonyl, lower alkylaminosulfonyl, arylcarbonyl, heteroarylcarbonyl, lower alkylcarbonyl, lower alkoxycarbonyl, aminocarbonyl, lower alkylaminocarbonyl or carboxy; R 3 is alkyl, hydroxy-lower alkyl, methoxy-lower alkyl, aryl-lower alkyl, heteroaryl-lower alkyl or aryl; and R 4 and R 5 are, independently of each other, hydrogen, ortho- or meta-fluoro, ortho- or meta-chloro, ortho- or meta-methoxy, ortho-nitro, ortho-, meta- or para-methyl, or ortho-, meta- or para-hydroxy; and wherein at least one of R 4 and R 5 is different from hydrogen; and tautomers and salts thereof.