Patent ID: 8906962

Claim:
A method of growing hair, wherein the method comprises topically applying to mammalian skin a safe and effective amount of a composition comprising: A) an active ingredient selected from the group consisting of a prostaglandin F analog of the following structure: and pharmaceutically acceptable salts thereof; wherein R 1 is selected from the group consisting of C(O)NHOH, CH 2 OH, S(O) 2 R 3 , C(O)NHR 3 , C(O)NHS(O) 2 R 4 , and tetrazole; R 2 is selected from the group consisting of a hydrogen atom, a lower heterogeneous group, and a lower monovalent hydrocarbon group; R 3 is selected from the group consisting of a monovalent hydrocarbon group, a heterogeneous group, a carbocyclic group, a heterocyclic group, an aromatic group, a heteroaromatic group, a substituted monovalent hydrocarbon group, a substituted heterogeneous group, a substituted carbocyclic group, a substituted heterocyclic group, a substituted aromatic group, and a substituted heteroaromatic group; R 4 is selected from the group consisting of a monovalent hydrocarbon group, a heterogeneous group, a carbocyclic group, a heterocyclic group, an aromatic group, a heteroaromatic group, a substituted monovalent hydrocarbon group, a substituted heterogeneous group, a substituted carbocyclic group, a substituted heterocyclic group, a substituted aromatic group, and a substituted heteroaromatic group; X is selected from the group consisting of —CC—, a covalent bond, —CH═C═CH—, —CH═CH—, —CH═N—, —C(O)—, —C(O)Y—, —(CH 2 ) n —, wherein n is 2 to 4, —CH 2 NH—, —CH 2 S—, and —CH 2 O—; Y is selected from the group consisting of a sulfur atom, an oxygen atom, and NH; and Z is selected from the group consisting of a carbocyclic group, a heterocyclic group, an aromatic group, a heteroaromatic group, a substituted carbocyclic group, a substituted heterocyclic group, a substituted aromatic group, and a substituted heteroaromatic group.