Patent ID: 8486996

Claim:
A compound of formula (I) wherein ring A is selected from rings of formula (A 1 ), (A 4 ) and (A 5 ) W represents CR 7 , N, or N→O; X represents CR 5 , N, or N→O; Y represents O or S; R 0 is NR 16 R 17 , lower alkoxymethyl, optionally substituted cyclohexyl, optionally substituted cyclohexenyl, lower alkyl or lower alkoxy substituted phenyl, optionally substituted pyridyl, optionally substituted dihydropyridyl, optionally substituted tetrahydropyridinyl, optionally substituted pyrimidinyl, optionally substituted tetrahydropyranyl, or optionally substituted dihydropyranyl, and wherein the optional substituents are lower alkyl or lower alkoxy; R 1 is hydrogen or NHR 15 ; R 5 represents hydrogen, lower alkyl, halo-lower alkyl or fluoro; R 6 is hydrogen; R 7 represents hydrogen, lower alkyl, hydroxy, lower alkoxy, lower alkenyloxy, lower alkinyloxy, cyano, halogen, or nitro; R 8 represents hydrogen or fluoro; R 9 represents hydrogen, lower alkyl or halogen; R 10 represents hydrogen, lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, cycloalkyl, hydroxy, lower alkoxy, halo-lower alkoxy, lower alkoxy-lower alkoxy, cycloalkyloxy, alkenyloxy, alkinyloxy, alkylmercapto, alkylsulfinyl, halo-lower alkylsulfinyl, alkylsulfonyl; amino optionally substituted by one or two substitutents selected from lower alkyl, cycloalkyl, cycloalkyl-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, di-lower alkylamino-lower alkyl, alkylcarbonyl, alkoxycarbonyl or aminocarbonyl, and wherein alkyl or lower alkyl in each case may be substituted by halogen, lower alkoxy, aryl, heteroaryl or optionally substituted amino, or wherein the two substituents on nitrogen form together with the nitrogen heterocyclyl; lower alkylcarbonyl, halo-lower alkylcarbonyl, optionally substituted phenylcarbonyl, carboxy, lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl; cyano, halogen, or nitro; R 11 represents hydrogen, lower alkyl, lower alkoxy, lower alkylamino, or halogen; R 12 represents hydrogen, lower alkyl, halo-lower alkyl or fluoro; R 15 represents hydrogen, lower alkylcarbonyl or lower alkylsulfonyl wherein lower alkyl may be substituted by hydroxy, lower alkoxy or halogen; or lower alkoxycarbonyl; R 16 and R 17 , independently of each other, represent lower alkyl, lower alkenyl or halo-lower alkyl, or R 16 and R 17 together with the nitrogen atom they are bound to form heterocyclyl; or pharmaceutically acceptable salts thereof.