Patent ID: 7176322

Claim:
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: represents a double; R 1 is R b ; R 2 is C 1-8 alkyl or C 1-4 haloalkyl; R 3 is H, C 1-4 haloalkyl or C 1-8 alkyl; R 4 is H, C 1-4 haloalkyl or C 1-8 alkyl; R 5 is, independently, in each instance, H, C 1-8 alkyl, C 1-4 haloalkyl, halogen, —OC 1-6 alkyl, —NR a R d or NR d C(═O)R d ; R 6 is R d , C 1-4 haloalkyl, —C(═O)R c , —OC 1-6 alkyl, —OR b , —NR a R a , —NR a R b , —C(═O)OR c , —C(═O)NR a R a , —OC(═O)R c , —NR a C(═O)R c , cyano, nitro, —NR a S(═O) m R c or —S(═O) m NR a R a ; R 7 is R d , C 1-4 haloalkyl, —C(═O)R c , —OC 1-6 alkyl, —OR b , —NR a R a , —NR a R b , —C(═O)OR c , —C(═O)NR a R a , —OC(═O)R c , —NR a C(═O)R c , cyano, nitro, —NR a S(═O) m R c or —S(═O) m NR a R a ; or R 6 and R 7 together form a 3- to 6-atom saturated or unsaturated bridge containing 0, 1, 2 or 3 N atoms and 0, 1 or 2 atoms selected from S and O, wherein the bridge is substituted by 0, 1 or 2 substituents selected from R 5 ; wherein when R 6 and R 7 form a benzo bridge, then the benzo bridge may be additionally substituted by a 3- or 4-atoms bridge containing 1 or 2 atoms selected from N and O, wherein the bridge is substituted by 0 or 1 substituents selected from C 1-4 alkyl; R a is, independently, at each instance, H, C 1-4 haloalkyl or C 1-6 alkyl; R b is, independently, at each instance, phenyl, benzyl, naphthyl or a saturated or unsaturated 5- or 6-membered ring heterocycle containing 1, 2 or 3 atoms selected from N, O and S, with no more than 2 of the atoms selected from O and S, wherein the phenyl, benzyl or heterocycle are substituted by 0, 1, 2 or 3 substituents selected from C 1-6 alkyl, halogen, C 1-4 haloalkyl, —OC 1-6 alkyl, cyano and nitro; R c is, independently, at each instance, C 1-6 alkyl, C 1-4 haloalkyl, phenyl or benzyl; R d is, independently, at each instance, H, C 1-6 alkyl, phenyl, benzyl or a saturated or unsaturated 5- or 6-membered ring heterocycle containing 1, 2 or 3 atoms selected from N, O and S, with no more than 2 of the atoms selected from O and S, wherein the C 1-6 alkyl, phenyl, benzyl, naphthyl and heterocycle are substituted by 0, 1, 2, 3 or 4 substituents selected from C 1-6 alkyl, halogen, C 1-4 haloalkyl, —OC 1-6 alkyl, cyano and nitro, R b , —C(═O)R c , —OR b , —NR a R a , —NR a R b , —C(═O)OR c , —C(═O)NR a R a , —OC(═O)R c , —NR a C(═O)R c , —NR a S(═O) m R c and —S(═O) m NR a R a ; X is —NR d —; Y is ═CR 6 ; and Z is —CR 7 ; and m is 1 or 2.