Patent ID: 8193218

Claim:
A method of treating a disorder induced by substance P selected from the group consisting of: pain, migraines, anxiety, vomiting, schizophrenia, depression; motor disorders such as Parkinson's disease, inflammatory diseases such a rheumatoid arthritis, iritis and conjunctivitis, diseases of the respiratory organs such as asthma and chronic bronchitis, diseases of the gastrointestinal system such as ulcerative colitis and Crohn's disease, and hypertension, comprising: administering a therapeutically effective amount of a compound according to formula 1, wherein Y is ═N or ═N(O)—, R is OH when Y is ═N— and R is H when Y is ═N(O)— and the ring A is unsubstituted or mono- or poly-substituted by substituents selected from the group consisting of lower alkyl, lower alkoxy, halogen, nitro and trifluoromethyl, provided that when R is OH and Y is ═N— the ring A is not unsubstituted, and pharmaceutically acceptable salts thereof, to an animal in need thereof.