Patent ID: 7196096

Claim:
A method of treatment of psychotic disorders or intellectual impairment disorders, which comprises administering a therapeutically effective amount of a compound of formula I, wherein NRR 1 is attached at the 5- or 6-position of the furopyridine ring; R is hydrogen, C 1 –C 4 alkyl, or COR 2 ; R 1 is CH 2 CH═CHAr or CH 2 C≡CAr; n is 0 to 3; A is N or NO; Ar is a 5- or 6-membered aromatic or heteroaromatic ring which contains zero to four nitrogen atoms, zero to one oxygen atoms, and zero to one sulfur atoms; or; an 8-, 9- or 10-membered fused aromatic or heteroaromatic ring system containing zero to four nitrogen atoms, zero to one oxygen atoms, and zero to one sulfur atoms; any of which may optionally be substituted with one to two substituents independently selected from: halogen, trifluoromethyl, or C 1 –C 4 alkyl; R 2 is hydrogen, C 1 –C 4 alkyl; C 1 –C 4 alkoxy; or phenyl ring optionally substituted with one to three of the following substituents: halogen, C 1 –C 4 alkyl, C 2 –C 4 alkenyl, C 2 –C 4 alkynyl, OH, OC 1 –C 4 alkyl, CO 2 R 5 , —CN, —NO 2 , —NR 3 R 4 , or —CF 3 ; R 3 , R 4 and R 5 are independently hydrogen; C 1 –C 4 alkyl; or phenyl ring optionally substituted with one to three of the following substituents: halogen, C 1 –C 4 alkyl, C 2 –C 4 alkenyl, C 2 –C 4 alkynyl, OH, OC 1 –C 4 alkyl, —CN; —NO 2 , or —CF 3 ; or an enantiomer thereof, and pharmaceutically acceptable salts thereof.