Patent ID: 6977265

Claim:
A compound of Formula (I): wherein: R 1 is (C 1 -C 2 )alkylene; R 2 is optionally substituted phenyl; R 3 is hydrogen, alkyl, acyl, aryl, or arylalkyl; ring A and the two carbons it is attached to form, a ring selected from cyclopropyl, cyclobutyl, or cyclopentyl and cyclohexyl; L is —C(═O)—, —C(═S)—, —SO 2 —, —C(═O)N(R a )—, —C(═S)N(R a )—, —SO 2 N(R a )—, —C(═O)O—, —C(═S)O—, —S(═O) 2 O—; where R a is hydrogen, alkyl, acyl, aryl, arylalkyl, alkoxycarbonyl, or benzyloxycarbonyl; X is absent, —(CR′R″)O—, —(CR′R″)S—, —(CR′R″)NR b — or alkylene; where R′ and R″ are independently hydrogen or alkyl, and R b is hydrogen or alkyl; R 4 is optionally substituted aryl or optionally substituted heteroaryl; and R 5 is hydrogen or alkyl; provided that when R 1 is —CH 2 —, R 2 is phenyl, R 3 is hydrogen, R 5 is hydrogen, A is phenyl, L is —C(═O)NH— and X is absent, then R 4 is not 2,5-difluorophenyl; or individual isomers, racemic and non-racemic mixtures of isomers, and pharmaceutically acceptable salts thereof.