Patent ID: 7115634

Claim:
A compound of the formula in racemic, enantiomeric form or all combinations of these forms, wherein R 1 is —(CH 2 ) m -Y-Z 11 or —(CH 2 ) m -Z 12 , Z 11 is (C 1 -C 6 )alkyl or optionally substituted aryl, Z 12 is bis-phenyl optionally substituted aryl or -optionally substituted heteroaryl, R 2 is selected from the group consisting of —C(Y)NHX 1 , —C(O)X 2 and SO 2 X 3 ; R 3 is selected from the group consisting of hydrogen, an optionally substituted alkyl, alkenyl and alkynyl, X 1 is selected from the group consisting of (C 1 -C 15 )alkyl, alkenyl, alkynyl, —(CH 2 ) m -Y-Z 21 and —(CH 2 ) p Z 22 , Z 21 is (C 1 -C 6 )alkyl Z 22 is selected from the group consisting of cyclohexenyl, indanyl, bis-phenyl, (C 3 -C 7 )cycloalkyl and (C 3 -C 7 )heterocycloalkyl, aryl and heteroaryl optionally substituted X 2 is selected from the group consisting of alkenyl optionally substituted by phenyl optionally substituted, alkynyl, —(CH 2 ) m -W-(CH 2 ) q -Z 23 and —(CH 2 ) p -U-Z 24 wherein Z 23 is (C 1 -C 6 )alkyl or aryl optionally substituted; Z 24 is selected from the group consisting of cyclohexenyl, bis-phenyl, (C 3 -C 7 )cycloalkyl optionally substituted, (C 3 -C 7 )heterocycloalkyl, cyano, amino, mono and di-alkylamino, aryl and heteroaryl optionally substituted, X 3 is selected from the group consisting of (C 1 -C 10 )alkyl, alkenyl optionally substituted by phenyl optionally substituted, —CF 3 , and —(CH 2 ) p Z 25 , Z 25 is aryl optionally substituted, Y is oxygen or sulfur, W is oxygen or sulfur or SO 2 ; U is a covalent bond or oxygen; n is an integer from 0 to 4; m is an integer from 1 to 6; p is an integer from 0 to 6; q is an integer from 0 to 2, and their addition salts with pharmaceutically acceptable acids.