Patent ID: 8871728

Claim:
A compound of Formula I or II: wherein M represents a macrolide subunit, E is a C 1-6 group, optionally containing one or more heteroatoms, wherein the carbon atoms and/or heteroatoms are in a linear and/or cyclic arrangement, D is a substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl group, A is a linking group connected to D, B is an alkyl, heteroalkyl, alkylaryl or alkylheteroaryl spacer group, ZBG is a Zinc Binding Group comprising a heterocyclic moiety, R 13 is selected from hydrogen, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 2-6 alkenyl group, a substituted or unsubstituted C 2-6 alkynyl group, a substituted or unsubstituted C 1-6 alkanoate group, a substituted or unsubstituted C 2-6 carbamate group, a substituted or unsubstituted C 2-6 carbonate group, a substituted or unsubstituted C 2-6 carbamate group, or a substituted or unsubstituted C 2-6 thiocarbamate group, R 14 and R 16 is selected from hydrogen, hydroxyl, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 2-6 alkenyl group, a substituted or unsubstituted C 2-6 alkynyl group, a substituted or unsubstituted C 1-6 alkanoate group, a substituted or unsubstituted C 2-6 carbamate group, a substituted or unsubstituted C 2-6 carbonate group, a substituted or unsubstituted C 2-6 carbamate group, or a substituted or unsubstituted C 2-6 thiocarbamate group, R 15 is hydrogen or —OR 17 , R 17 is selected from a group consisting of hydrogen, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 2-6 alkenyl group, a substituted or unsubstituted C 2-6 alkynyl group, a substituted or unsubstituted C 1-6 alkanoate group, a substituted or unsubstituted C 2-6 carbamate group, a substituted or unsubstituted C 2-6 carbonate group, a substituted or unsubstituted C 2-6 carbamate group, or a substituted or unsubstituted C 2-6 thiocarbamate group.