Patent ID: 8486706

Claim:
A method for identifying a subject that benefits from a cardiac therapy without a risk of renal failure, wherein the subject is suffering from heart failure and is without an apparent renal disorder as assessed by glomerular filtration rate or creatinine clearance, the method comprising the steps of a) contacting a sample from the subject with a ligand having specific binding affinity for liver fatty acid binding protein (L-FABP), b) contacting a sample from the subject with a ligand having specific binding affinity for an additional polypeptide from the group consisting of a cardiac troponin and a natriuretic peptide; c) calculating an amount of L-FABP based on the contacting step (a); d) calculating an amount of additional polypeptide based on contacting step (c); e) comparing the calculated amount of the L-FABP to a reference amount of L-FABP; f) comparing the calculated amount of additional polypeptide to a reference amount of additional polypeptide, and g) identifying the subject as one who will benefit from cardiac therapy without a risk of renal failure only when the calculated amount of L-FABP is lower than the reference amount of L-FABP and when the calculated amount of the additional polypeptide is greater than the reference amount of additional polypeptide.