Patent ID: 7541369

Claim:
A compound of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereo-chemically isomeric forms thereof, wherein n and m are 1; t is 0 or 1 and when t is 0 then a direct bond is intended; Q, X, or Y can be nitrogen or carbon; with the proviso that one of Q, X, or Y is nitrogen and the others of Q, X or Y are carbon; Z is —CH 2 —; R 1 is —C(O)NR 3 R 4 , —C(O)—C 1-6 alkanediylSR 7 , —NR 8 C(O)N(OH)R 7 , —NR 8 C(O)C 1-6 alkanediylSR 7 , —NR 8 C(O)C═N(OH)R 7 wherein R 3 and R 4 are each independently selected from hydrogen, hydroxy, hydroxyC 1-6 alkyl, aminoC 1-6 alkyl; and R 7 is independently selected from hydrogen, C 1-6 alkyl, C 1-6 alkylcarbonyl, arylC 1-6 alkyl, C 1-6 alkylpyrazinyl, pyridinone, pyrrolidinone or methylimidazolyl; and R 8 is independently selected from hydrogen or C 1-6 alkyl; R 2 is hydrogen, hydroxy, amino, hydroxyC 1-6 alkyl, C 1-6 alkyl, C 1-6 alkyloxy, phenylC 1-6 alkyl, aminocarbonyl, aminoC 1-6 alkyl, C 1-6 alkylaminoC 1-6 alkyl or di(C 1-6 alkyl)aminoC 1-6 alkyl; -L- is carbonyl, or sulfonyl; wherein s is 0 or 1; and R 5 is hydrogen or phenyl.