Patent ID: 7622492

Claim:
A compound of the formula (I): wherein: R 1 is aryl, heteroaryl, aralkyl, heteroaralkyl, lower alkyl, lower-alkoxy-benzyl, lower-alkoxy-carbonyl-lower-alkyl, halo-lower-alkyl, hydroxy-lower-alkyl, lower-alkoxy-lower-alkyl, (CH 2 )s-aryl, (CH2)s-heteroaryl or (CH 2 )s-cycloalkyl, wherein said aryl, heteroaryl, aralkyl, heteroaralkyl (CH 2 )s-aryl, (CH2)s-heteroaryl or (CH 2 )s-cycloalkyl is unsubstituted or substituted with one or more substituents selected from the group consisting of halogen, lower alkyl, lower alkoxy, cyano, lower-alkoxy-carbonyl, halo-lower-alkyl, phenyl-(oxo-lower-alkyl) and hydroxy-lower-alkyl; p is 0 or 1; s is 0, 1 or 2; and R 2 is phenyl, which may be unsubstituted or substituted with one or more substituents selected from the group consisting of halogen, hydroxy, halo-lower-alkyl, lower alkoxy, trifluoromethoxy, aminocarbonyl, lower-alkyl, nitro, cyano, sulfonamido, lower-alkyl-sulfonyl, lower acyl and lower-alkoxy-carbonyl, halo-lower-alkyl, unsubstituted or substituted naphthyl, biphenyl, which may be unsubstituted or substituted with one or more substituents selected from the group consisting of acetyl, halogen, lower-alkoxy and lower-alkyl, a 5- or 6-membered monocyclic heterocycle with 1-3 atoms selected from N, O and S, which may be unsubstituted or substituted with halogen, lower-alkyl, unsubstituted or substituted phenyl, or halo-lower-alkyl, or unsubstituted or substituted benzothiophene, with the proviso that the following compounds are excluded: 1,7,8,8-Tetramethyl-2-phenyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one, 2,7,8,8-Tetramethyl-1-phenyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one, 1,7,8,8-Tetramethyl-2-naphthalen-2-yl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one, 1,7,8,8-Tetramethyl-2-p-tolyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one, 2-(4-Methoxy-phenyl)-1,7,8,8-tetramethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one and 1,7,8,8-Tetramethyl-2-o-tolyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one.