Patent ID: 8694099

Claim:
A method of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes, comprising: a) pacing using the right ventricular electrode and a pacing left ventricular electrode using a first A-V delay; b) measuring activation times at other ones of the left ventricular electrodes in response to pacing the right ventricular electrode and a pacing left ventricular electrode; c) determining a weighted electrical dyssynchrony associated with the first A-V delay; d) pacing using the right ventricular electrode and the pacing left ventricular electrodes using a second A-V delay; e) measuring activation times at other ones of the left ventricular electrodes the right ventricular electrode and a pacing left ventricular electrode; and f) determining a weighted electrical dyssynchrony for the second A-V delay; g) comparing weighted electrical dyssynchrony for the first and the second A-V delays; and h) selecting an optimal A-V delay in response to comparing weighted electrical dyssynchrony for the first and the second A-V delays, wherein the weighted electrical dyssynchrony is determined using ED ⁡ ( I , A , D ) = ∑ i = 1 n ⁢ w ⁡ ( 1 , I ) ⁢ AT ⁡ ( 1 , A , D ) wherein factor w(i, j) is a distance of a sensing electrode I from a pacing electrode, n is a total number of left ventricular electrodes, atrio-ventricular delay, and D is a time delay between pacing pulses in a right ventricle and a left ventricle.