Patent ID: 7037925

Claim:
A compound of formula (IA): in which Ar is phenyl substituted by ethyl, propyl, hydroxymethyl or CO 2 H or disubstituted by methyl and hydroxymethyl; R 1 is methoxy, ethoxy or a group OCH 2 CONH 2 , OCH 2 CH 2 OCH 3 , or O(CH 2 ) p NR 4 R 5 where p is 2 or 3 and R 4 and R 5 are hydrogen, methyl, ethyl or propyl or together R 4 and R 5 form a pyrrolidine, imidazole or morpholine ring; R 2 is methoxy, ethoxy or O(CH 2 ) p NR 4 R 5 where p is 2, 3 or 4 and R 4 and R 5 are hydrogen, methyl or ethyl or one of R 4 or R 5 is methyl and the other is pyridyl or pyrazole or R 4 and R 5 form a piperidine, hydroxypiperidine, thiomorpholine, morpholine, pyrrolidine, 2,6-dimethylmorpholine imidazole or triazole ring, or a pharmaceutically acceptable salt or solvate thereof, provided that when A is phenyl substituted by ethyl or propyl or disubstituted by methyl, then R 1 and R 2 are not both methoxy, R 1 and R 2 are not both ethoxy or one of R 1 /R 2 is not methoxy when the other is ethoxy.