Patent ID: 8877975

Claim:
A compound having a structure according to Formula (II): wherein m is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10; Ar is wherein Y and Z are (i) both halogen; or (ii) one of Y and Z is CF 3 or OCF 3 , and the other is hydrogen; each X is independently H, halogen, CF 3 , OR 5 , acyl, C(O)OR 5 , NR 6 R 7 , substituted or unsubstituted alkyl, or substituted or unsubstituted heteroalkyl; wherein each R 5 is independently H, acyl, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, or substituted or unsubstituted aryl; each R 6 and R 7 is independently H, or substituted or unsubstituted alkyl; each R 1 and R 2 is independently H, or substituted or unsubstituted alkyl; and R 3 and R 4 are each independently H, substituted or unsubstituted alkyl, or substituted or unsubstituted heteroalkyl; or a pharmaceutically acceptable salt, enantiomer, diastereomer, racemic mixture, enantiomerically enriched mixture, or enantiomerically pure form thereof; wherein substituents for alkyl or heteroalkyl radicals are selected from unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted aryl, unsubstituted heteroaryl, unsubstituted heterocycloalkyl, —OR′, ═O, ═NR′, ═N—OR′, —NR′R″, —SR′, -halogen, —SiR′R″R′″, —OC(O)R′, —C(O)R′, —CO 2 R′, —CONR′R″, —OC(O)NR′R″, —NR″C(O)R′, —NR′—C(O)NR″R′″, —NR″CO 2 R′, —NR—C(NR′R″R′″)═NR″″, —NR—C(NR′R″)═NR′″, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —NRSO 2 R′, —CN and —NO 2 in a number ranging from zero to (2m′+1), where m′ is the total number of carbon atoms in such a radical; R′, R″, R′″ and R′″ are each independently selected from hydrogen, unsubstituted heteroalkyl, unsubstituted aryl, unsubstituted alkyl, alkoxy or thioalkoxy groups, or arylalkyl groups; and substituents for aryl radicals are selected from unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted aryl, unsubstituted heteroaryl, unsubstituted heterocycloalkyl, —OR′, ═O, ═NR′, ═N—OR′, —NR′R″, —SR′, -halogen, —SiR′R″R′″, —OC(O)R′, —C(O)R′, —CO 2 R′, —CONR′R″, —OC(O)NR′R″, —NR″C(O)R′, —NR′—C(O)NR″R′″, —NR″CO 2 R′, —NR—C(NR′R″R′″)═NR″″, —NR—C(NR′R″)═NR′″, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —NRSO 2 R′, —CN, —NO 2 , —R′, —N 3 , —CH(Ph) 2 , fluoro(C 1 -C 4 )alkoxy, and fluoro(C 1 -C 4 )alkyl, in a number ranging from zero to the total number of open valences on the aromatic ring system; and where R′, R″, R′″ and R′″ are each independently selected from hydrogen, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted aryl and unsubstituted heteroaryl.