Patent ID: 7939677

Claim:
An oligomeric compound having at least one 4′-thionucleoside of formula IIa: wherein, independently, for each 4′-thionucleoside of formula IIa: one of T 3 and T 4 is an internucleoside linking group linking the 4′-thionucleoside of formula IIa to the oligomeric compound and the other of T 3 and T 4 is H, a protecting group, a conjugate group or an internucleoside linking group linking the 4′-thionucleoside of formula IIa to the oligomeric compound; Bx is hydrogen or a nucleobase; X is fluoro, substituted or unsubstituted O—C 1 -C 12 alkyl, substituted or unsubstituted O—C 2 -C 12 alkenyl, or substituted or unsubstituted O—C 2 -C 12 alkynyl.