Patent ID: 8008301

Claim:
A compound structurally represented by Formula I or a pharmaceutically acceptable salt thereof wherein: Q, T, X, and D independently represent carbon or nitrogen, provided that no more than two of Q, T, X, and D are nitrogen; R1, R2, and R3 are independently at each occurrence —H, -halogen, —(C 1 -C 7 ) alkyl, —CN, —C(O)R7, —C(O)(C 3 -C 5 )cycloalkyl, —C(O)NR7R8, —OCF 3 , —OR7, —NO 2 , —NR7R8, —NR9SO 2 R7, —NR9C(O)R7, —NR9CO 2 R7, —NR9C(O)NR7R8, —SR7, —SO 2 R7, —SO 2 CF 3 , —SO 2 NR7R8, —S(O)R7, —O(CH 2 )mNR7R8, -heteroaryl-R9, -phenyl-R9, provided however that wherein D is nitrogen, then R1 or R2 or R3 are not attached to D, and provided that wherein X is nitrogen, then R1 or R2 or R3 are not attached to X, and provided that wherein T is nitrogen, then R1 or R2 or R3 are not attached to T, and provided that wherein Q is nitrogen, then R1 or R2 or R3 are not attached to Q; and further provided that when D and X are carbon, then R1 and R2 can combine to form a 5 or 6 membered ring with D and X, wherein the ring so formed may optionally include one double bond in the case of a five membered ring or two double bonds in the case of a six membered ring, and wherein one to three ring atoms may optionally be heteroatoms independently selected from N, O, or S; wherein m is 1, 2, 3 or 4; R4 and R5 are independently at each occurrence —H, —OH, -halogen, —CF 2 H, —CF 3 , —(C 1 -C3)alkyl, —O—(C 1 -C 3 ) alkyl, R6 is independently at each occurrence —H, -halogen, —CF3, —(C 1 -C 3 ) alkyl, —NH 2 , —NR7R8, —OH, —OR7; R7 and R8 are independently at each occurrence —H, —(C 1 -C 6 ) alkyl, Wherein R7 and R8 can combine with the atom to which they are attached to form a 3 to 7 membered ring; R9 is independently at each occurrence —H, —(C 1 -C 3 ) alkyl, provided the compound is not (3-Fluoro-4′-methanesulfonyl-biphenyl-4yl)-[-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone, or [4-(6-amino-5-hydroxy-pyridin-3-yl) -phenyl]-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone.