Patent ID: 6875771

Claim:
A compound of Formula I or a nontoxic pharmaceutically acceptable salt or solvate thereof, wherein: R 1 is napthyl or phenyl, said phenyl optionally substituted with one to three substituents each independently selected from the group consisting of halogen, C 1-4 alkyl, and trifluoromethoxy; R 2 is 5-methylpyridin-2-yl or C 1-4 alkyl, said C 1-4 alkyl optionally substituted with hydroxy; R 3 is hydrogen, halogen, C 1-4 alkyl, or benzyloxy; R 4 is hydrogen or C 1-4 alkyl; the dashed line, taken with R 3 and R 4 together, optionally forms a 5 to 6 member aromatic ring structure having zero to 2 heteroatoms; R 5 is hydrogen, halogen, C 1-4 alkyl, benzyl, or C(O)R 8 ; X is NR 6 , O, or S(O) m ; Y is NR 7 or O; m is 0, 1 or 2; R 6 is hydrogen or C 1-4 alkyl; R 7 is hydrogen, C 1-4 alkyl, or C(O)C 1-4 alkyl; and R 8 is C 1-4 alkoxy, amino, (C 1-4 alkyl)amino, di(C 1-4 alkyl)amino, or hydroxy.