Patent ID: 7479561

Claim:
A compound of Formula I wherein: R 1 and R 2 may be the same or different and are selected from H, alkyl of 1 to 6 carbon atoms, (CH 2 ) n XR 4 , (CH 2 ) n NZZ′, alkenyl of 2-6 carbon atoms, alkynyl of 2-6 carbon atoms, aryl, or heteroaryl; R 1 and R 2 can be taken together with the nitrogen to which they are attached to form a heterocyclic ring optionally having an additional heteroatom selected from nitrogen, oxygen, and sulfur, wherein the sulfur can be mono or di-oxidized, optionally substituted with at least one —R 3 on a carbon or nitrogen, or on nitrogen by a group —(CH 2 ) n XR 4 , —(CH 2 ) n NZZ′, or on carbon by a group —(CH 2 ) q XR 4 , —(CH 2 ) q NZZ′, halogen Z and Z′ are selected from H, alkyl of 1 to 6 carbon atoms alkenyl of 2-6 carbon atoms, alkynyl of 2-6 carbon-atoms, aryl, or heteroaryl; and Z and Z′ can be taken together with the nitrogen to which they are attached to form a heterocyclic ring optionally containing an additional heteroatom selected from nitrogen, oxygen and sulfur; R 3 is alkyl of 1 to 6 carbon atoms, alkenyl of 2-6 carbon atoms, alkynyl of 2-6 carbon atoms, oxygen, alkylaryl, alkylheteroaryl, cycloalkyl, aryl or heteroaryl, wherein the aryl or heteroaryl are optionally substituted with one or more alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, halogen, —OH, alkylhydroxy or trifluoromethyl; R 4 is H, alkyl of 1 to 6 carbon atoms, alkenyl of 2-6 carbon atoms, alkynyl of 2-6 carbon atoms, aryl or heteroaryl; X is O, S, NR 4 ; n is 2-5; q is 0-5; and pharmaceutically acceptable salts thereof.