Patent ID: 7476682

Claim:
A method of inhibiting an activity of a 5HT2A receptor comprising contacting the 5HT2A receptor with an amount of one or more of the compounds of Formula I that is effective in inhibiting the activity of the 5HT2A receptor, wherein the compound of Formula I has the structure: or a pharmaceutically acceptable salt thereof, wherein: R 1 is an optionally substituted heterocyclyl; R 2 and R 3 are independently selected from the group consisting of hydrogen, C 1-6 -alkyl and halogen or such that R 2 together with R 3 forms a 3-, 4-, 5-, 6-, 7-membered ring system with the atoms of the piperdinyl ring; m is 1; n is selected from the group consisting of 1, 2, and 3; Ar 1 is an optionally substituted aryl or heteroaryl; W is selected from the group consisting of oxygen and sulfur; X is selected from the group consisting of optionally substituted methylene, optionally substituted ethylene, optionally substituted propylene, optionally substituted vinylene, and CH 2 N(R N ), wherein R N is selected from hydrogen and C 1-6 -alkyl; and Ar is an optionally substituted aryl or heteroaryl.