Patent ID: 8277831

Claim:
A delivery vehicle suitable for local, non-systemic administration of a drug to a body and directly to tissue within a body cavity having been subjected to a surgical procedure, said vehicle comprising Pemirolast or an analog thereof in an amount effective to inhibit formation of post-operative adhesions upon local, non-systemic administration of said Pemirolast to said tissue, wherein the delivery vehicle is selected from the group consisting of microcapsules, microspheres, barriers, liposomes, fibers, filaments, gels, foams and films, and wherein said delivery vehicle comprises a polymer selected from the group consisting of poloxamers, poly(orthoester)s, poly(vinyl alcohol)s, poly(anhydride)s, poly(methacrylate)s, poly(methacryladmide)s, anionic carbohydrate polymers, poly(hydroxybutyric acid)s, polyacetals, poly(l-lactide), poly(dl-lactide), poly(dl-lactide-co-glycolide)s, poly(l-lactide-co-glycolide)s, poly(e-caprolactone), polyglycolide, poly(p-dioxanone)s, poly(trimethylene carbonate), poly(alkylene diglycolate)s, poly(oxaester)s, poly(oxaamide)s and glyceride polymers, and the Pemirolast or analog thereof is present in an amount of from about 0.01 milligram Pemirolast or analog thereof per kilogram of the body to about 3,000 milligram Pemirolast or analog thereof per kilogram of the body.