Patent ID: 7173107

Claim:
A process for preparing a protected glycopeptide of formula 1 comprising: coupling a muramylamide compound of formula 2 with a glucopyranosyl compound of formula 3 to form said glycopeptide of formula 1, wherein: A is Br or Cl; Pg 0 is an acyl hydroxy-protecting group; Pg 1 is a hydroxy-protecting group which is not electron withdrawing; Pg 2 is an amine-protecting group which does not lead to oxazoline formation; Pg 5 is a hydroxy-protecting group; Pg 0 , Pg 1 , Pg 2 and Pg 5 are orthogonal protecting groups; and Y is a residue of an amino acid or peptide of 2 to 5 amino acid residues, wherein: Y forms an amide linkage with the attached carbonyl; and Y comprises a protected terminal carboxy group.