Patent ID: 8853261

Claim:
A process for producing a composition with antibacterial activity, comprising an enriched Garcinia mangostana extract, said process comprising the step of: a) demethylating a hydroalcoholic extract of a fruit pericarp (fruit hull) of Garcinia mangostana in an organic solvent, wherein said hydroalcoholic extract comprises α-mangostin and minor amounts of other xanthones, said demethylating being performed in the presence of a Lewis acid, an organic base, and a catalyst to yield composition-I enriched in demethylated xanthones, wherein said composition-I comprises γ-mangostin in the range of 20% to 40% of total weight of composition-I, α-mangostin in the range of 0 to 3%, garcinone C in the range of 0.5 to 3% and 3-isomangostin in the range of 0.5 to 2.5%.