Patent ID: 8404088

Claim:
A method for preparing a compound with an aglain core structure, the method comprising steps of: producing an oxidopyrylium species (I T ) by photoinduced excited state intramolecular proton transfer of a 3-hydroxychromone derivative (I); and reacting the oxidopyrylium species with a dipolarophile (IV) to obtain the aglain core-containing compound (V), wherein compounds (I), (I T ), (IV) and (V) have the following chemical structures: wherein R 1 , R 2 , R 3 , R 4 , R, R a and R b are identical or different and selected from the group consisting of hydrogen, halogen, hydroxy, alkoxy, aryloxy, heteroalkoxy, heteroaryloxy, thioalkyl, thioaryl, acyl, aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, heteroaromatic, aryl, heteroaryl, alkylamino, amino alkyl, arylamino, amino aryl, a protecting group, —NO 2 , —CN, —CF 3 , —CH 2 CF 3 , —CHCl 2 , —CH 2 OH, —CH 2 CH 2 OH, —CH 2 SO 2 CH 3 , —C(═O)R x , —CO 2 (R x ), —C(═O)N(R x ) 2 , —OC(═O)N(R x ) 2 , —OC(═O)R x , —OCO 2 R x , —S(O)R x , —S(O) 2 R x , —NR x (CO)R x , —N(R 2 )CO 2 R x , —N(R x )C(═O)N(R x ) 2 , —N(R x )S(O) 2 R x , and —S(O) 2 N(R x ) 2 , wherein each occurrence of R x is independently selected from the group consisting of hydrogen, aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, heteroaromatic, aryl, and heteroaryl, and wherein the steps of producing the oxidopyrylium species and of reacting the oxidopyrylium species with a dipolarophile are carried out in the presence of a TADDOL derivative selected from the group consisting of: