Patent ID: 8129123

Claim:
A method of determining whether a therapy is effective for treating coronary artery disease, the method comprising: a) obtaining a first sample comprising plasma from a subject; b) obtaining a second sample comprising plasma from the subject following administration of a therapy to treat coronary artery disease; and c) determining the level of oxidized phospholipid (OxPL) associated with apoB-100 particles in each of the first and second samples; d) determining the level of all detectable apoB-100 (total apoB-100) particles in each of the first sample and second sample; e) calculating a ratio of OxPL:total apoB-100 in each of the first and second samples; f) indicating based upon the calculated ratios whether the therapy to treat coronary artery disease is effective, wherein an increase in the ratio of OxPL:total apoB-100 determined from the second sample in comparison to the level of OxPL:total apoB-100 determined for the first sample, is indicative of an effective therapy for coronary artery disease.