Patent ID: 7125891

Claim:
A compound of formula (I) a stereochemically isomeric form thereof, or a pharmaceutically acceptable addition salt thereof, wherein n is [an integer 0] 1; X represents [O; or ]—(CR 4 R 5 ) m — wherein m is [an integer] 1or 2; R 4 and R 5 are each independently from each other hydrogen or C 1-4 alkyl; R 1 is C 1-6 alkylcarbonyl optionally substituted with hydroxy; [C 1-6 alkylcarbonyl]; aminoC 1-6 alkylcarbonyl wherein the C 1-6 alkyl group is optionally substituted with C 3-6 cycloalkyl; mono- and di(C 1-4 alkyl)aminoC 1-6 alkylcarbonyl; aminocarbonyl substituted with aryl; C 1-6 alkylcarbonyloxyC 1-6 alkylcarbonyl; C 1-6 alkyloxycarbonylaminoC 1-6 alkylcarbonyl wherein the amino group is optionally substituted with C 1-4 alkyl; an amino acid [residue ] bound via the carbonyl group; C 1-6 alkyl substituted with amino; or arylcarbonyl, wherein aryl is phenyl, or phenyl substituted with amino, nitro or hydroxycarbonyl; R 2 is [a 5-membered heterocycle selected from] wherein m′ is an integer 1 to 2; R 6 is hydrogen or C 1-4 alkyl; R 7 is independently from each other; halo; [amino]; [hydroxy;] trifluoromethyl; C 1-6 alkyl; phenyl; aminocarbonyl; hydroxycarbonyl; or C 1-4 alkyloxycarbonyl; [C 1-4 alkylcarbonyl; or C 1-4 alkyloxycarbonylC 1-4 alkylcarbonyl;] or R 2 is benzimidazole, or benzimidazole substituted with one or two substituents each independently selected from halo, trifluoromethyl, C 1-4 alkyl, hydroxy, hydroxycarbonyl, or C 1-4 alkyloxycarbonyl; R 3 is a bivalent radical of formula wherein said (b-1)[, (b-2), or (b-3)] optionally can be substituted with one, two or three substituents each independently selected from halo, hydroxy, C 1-6 alkyl, C 1-6 alkyloxy, nitro, amino, cyano, trifluoromethyl, phenyl, or phenyl substituted with one or two subsitutents each independently selected from halo, hydroxy, cyano, C 1-6 alkyl, C 1-6 alkyloxy, nitro, cyano, and trifluoromethyl.