Patent ID: 7332579

Claim:
An isolated antibody or an antigen binding fragment thereof that specifically binds to human ErbB4 of SEQ ID NO:2 with a Kd less than 100 nM and that comprises all of the complementarity determining regions (CDRs) of a heavy chain and all of the complementarity determining regions (CDRs) of a light chain from an antibody produced by a hybridoma selected from the group consisting of HER4.10H1.1A1 (ATCC Accession number PTA-2828), HER4.1C6.A11 (ATCC Accession Number PTA-2829), HER4.3B9.2C9 (ATCC Accession Number PTA-2826), HER4.1A6.5B3 (ATCC Accession Number PTA-2827) and HER4.8B1.2H2 (ATCC Accession Number PTA-2825), wherein both the heavy chain CDRs and the light chain CDRs are from the same hybridoma.