Patent ID: 8618296

Claim:
The compound of formula I-B 1 wherein U is â•Nâ€” or â•C(R 5 )â€”; V is â€”CHâ• or â€”Nâ•; W is â•CHâ€” or â•Nâ€”; with the proviso that only one of U, V or W is nitrogen; R 5 is hydrogen, methyl or halogen; R 1 is phenyl or heteroaryl, each of which is optionally substituted by one or two substituents, selected from halogen, lower alkyl and lower alkoxy; R 2 and R 2â€² are each independently hydrogen, lower alkyl, hydroxy, lower alkoxy, C 3 -C 6 -cycloalkyl, or CH 2 -lower alkoxy, or together with the carbon atom to which they are attached form a C 3 -C 6 -cycloalkyl group or a ring containing â€”CH 2 OCH 2 â€”; R 3 and R 3â€² are each independently hydrogen, lower alkyl, or CH 2 -lower alkoxy or together with the carbon atom to which they are attached form a C 3 -C 6 -cycloalkyl group; or R 3 and R 2 together with the carbon atom to which they are attached form a C 3-6 -cycloalkyl group or a ring containing â€”(CH 2 ) 2 OCH 2 â€”; and R 7 and R 7â€² are each independently hydrogen, hydroxy, lower alkyl or lower alkoxy; or a pharmaceutically acceptable acid addition salt, a racemic mixture, an enantiomer, an optical isomer and/or stereoisomer thereof.