Patent ID: 8383785

Claim:
A compound represented by formula (I): or a pharmaceutically acceptable salt or ester thereof, wherein V is —R 1 —(C═N-E-R 3 )—R 2 —, where E is and R 3 is C 1 -alkyl substituted with a monocyclic heteroaryl group or monocyclic aryl group wherein said monocyclic heteroaryl group or monocyclic aryl group is substituted with a substituted or unsubstituted monocyclic heteroaryl group R is hydrogen; W is selected from: (a) hydrogen; (b) hydroxy prodrug group; (c) —R 4 ; (d) —C(O)R 12 ; (e) —C(O)O—R 12 ; and (f) —C(O)N(R 9 R 10 ); one of A and B is R 11 and the other is OR 11 , wherein R 11 is independently selected from: (a) hydrogen; (b) —R 4 ; (c) —C(O)R 12 ; (d) —C(O)NHR 12 ; (e) —S(O) 2 R 12 ; (f) monosaccharide; and (g) —disaccharide; alternatively, A and B are taken together with the carbon atom to which they are attached to form: (a) C═O; or (b) C═CH-J-R 6 ; L is independently selected from R 4 ; Q is: (a) —R 12 ; (b) —C(O)R 12 ; (c) —C(O)NHR 12 ; (d) —C(O)OR 12 ; (e) —S(O) 2 R 12 ; (f) monosaccharide; (g) disaccharide; or (h) trisaccharide; Z is: (a) hydrogen; (b) —N 3 ; (c) —CN; (d) —NO 2 ; (e) —CONH 2 ; (f) —COOH; (g) —CHO; (h) —R 4 ; (i) —COOR 4 ; (j) —(C═O)R 4 ; or (k) —(C═O)NR 9 R 10 each of X and Y is independently: a) hydrogen; b) hydroxy; c) halogen; or d) —R 4 ; R 1 and R 2 are independently substituted or unsubstituted —C 1 -C 8 alkylene, or —C 2 -C 8 alkenylene—each containing 0, 1, 2, or 3 heteroatoms selected from O, S or N; R 4 is substituted or unsubstituted —C 1 -C 8 alkyl, —C 2 -C 8 alkenyl or —C 2 -C 8 alkenyl each containing 0, 1, 2, or 3 heteroatoms selected from O, S or N; R 5 is substituted or unsubstituted —C 3 -C 12 cycloalkyl each containing 0, 1, 2, or 3 heteroatoms selected from O, S or N; R 6 is selected from halogen and R 12 ; R 9 and R 10 are each independently selected from R 12 ; alternatively, R 9 and R 10 taken together with the nitrogen atom to which they are connected form a substituted or unsubstituted 3-to 10-membered ring which may optionally contain one or more heterofunctions selected from the group consisting of: —O—, —N(R 12 )—, —S(O) n —, wherein n =0, 1 or 2; and R 12 is selected from the group consisting of: (i) hydrogen; (ii) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (iii) R 4 ; and (iv) R 5 .