Patent ID: 8323617

Claim:
A sterile pharmaceutical composition comprising: (a) an effective amount of triamcinolone hexacetonide; and (b) an effective amount of a hyaluronic acid (HA) derivative, wherein the HA derivative is a cross-linked HA gel, wherein the cross-linked HA gel comprises at least one cross-link represented by the following structural formula: wherein each HA′ is a hyaluronic acid that is the same or different; each U is independently an optionally substituted O-acyl isourea or N-acyl urea; between about 1% and about 10% by mol of the carboxy functionalities of the HA gel is cross-linked, wherein the composition is formulated for administration as an intra-articular injection, and wherein the composition comprises about 2 mg/mL to about 30 mg/mL of the HA derivative.