Patent ID: 8911773

Claim:
A medicine system, comprising: 1) first and second opposing flexible plies forming an enclosure; 2) a seal, extending along at least a portion of a perimeter of the opposing plies with an enclosed cavity between the plies; 3) first and second opposing tabs, formed by a portion of the respective first and second opposing plies which extend beyond the seal; 4) a transdermal matrix or liquid reservoir system patch, disposed in the enclosed cavity between the first and second opposing plies, comprising: a) a backing layer; b) a compound selected from the group consisting of: i) a salt of testosterone; ii) methyltestosterone, androstenedione, adrenosterone, dehydroepiandrosterone, oxymetholone, fluoxymesterone, methandrostenolone, testolactone, pregnenolone, 17 a -methylnortestosterone, norethandrolone, dihydrotestosterone, danazol, androsterone, nandrolone, stanozolol, ethylestrenol, oxandrolone, bolasterone, mesterolone, testosterone propionate, testosterone cypionate, testosterone phenylacetate, testosterone enanthate, testosterone acetate, testosterone buciclate, testosterone heptanoate, testosterone decanoate, testosterone caprate, testosterone isocaprate and combinations thereof; and iii) combinations thereof; c) an adhesive layer with an exposed perimeter, wherein the adhesive layer comprises an adhesive; and d) a resilient release liner, removably attached over the adhesive layer so as to generate a spring force when displaced out of the flat configuration sufficient to overcome an adhesive force between the patch and one of the plies created by the adhesive layer leaking an adhesive from the exposed perimeter onto one of the plies; the seal including a resin; and the first and second opposing flexible plies having: i) a closed configuration in which a majority of the two plies are disposed in a planar layer; and ii) an open configuration in which at least a portion of the two plies are separated along the seal and pulled out of the planar layer and back across the planar layer to present the transdermal patch between the two plies.