Patent ID: 8193155

Claim:
A skin care composition containing at least one keratinocyte CLOCK or PER1 gene activator selected from the group consisting of: (SEQ ID No: 2) Tyr-Val-Ser-Thr-Pro-Tyr-Asn-NH 2 (SEQ ID No: 3) Val-Ser-Thr-Pro-Glu-NH 2 (SEQ ID No: 1) Ser-Thr-Pro-NH 2 (SEQ ID No: 4) Leu-His-Ser-Thr-Pro-Pro-NH 2 (SEQ ID No: 5) H 3 C-Arg-His-Ser-Thr-Pro-Glu-NH 2 (SEQ ID No: 6) H 3 C-His-Ser-Thr-Pro-Glu-NH-CH 3 and mixtures thereof; and at least one DNA repair enzyme selected from the group consisting of: base excision repair (BER) enzymes, nucleotide excision repair (NER) enzymes, DNA polymerases, DNA helicases, Mismatch repair (MMR) enzymes; and mixtures thereof.