Patent ID: 8349275

Claim:
A microfluidic device with microstructure, comprising: a base having a channel for accommodating a solution therein, the channel including a sensing section, and the sensing section having at least one microstructure, which is consisting of a plastic material without surface electric charge, arranged therein, wherein a plurality of ions migrate to a surface of the at least one microstructure to form a field-induced electrical double layer when the surface of the microstructure has been polarized by an electric field, wherein the base comprises an upper substrate and a lower substrate, one of the upper substrate and the lower substrate being formed with a band-like groove, such that the band-like groove forms the channel when the upper substrate and the lower substrate are assembled together, wherein the upper and the lower substrate are made of the plastic material; a sensing element being arranged in the sensing section, the sensing element being provided on an outer surface thereof with a noble metal nanoparticle layer; and two electrodes being electrically and respectively connected to two ends of the sensing section and receiving a high-frequency alternating-current (AC) signal to make a plurality of induced charges not neutralized and the field-induced electrical double layer maintained.