Patent ID: 7589083

Claim:
A method of treating a patient with a tumor, the method comprising administering to the patient a pharmaceutical comprising a heterocyclic compound having one or two quaternary ammonium groups to reduce the volume of the tumor, the compound having the formula: wherein R 1 and R 3-8 are independently hydrogen or C 1 -C 26 straight, branched or cyclic alkanes or alkenes, aromatic hydrocarbons, alcohols, ethers, aldehydes, ketones, carboxylic acids, amines, amides, nitriles or five—and/or six-membered heterocycle; wherein R 9 and R 10 considered together are ═O or ═CH-L-N + (R 11 , R 12 , R 13 ) (where -L-N + (R 11 , R 12 , R 13 ) is defined below) or R 9 and R 10 considered independently are —OH or L-N + (R 11 , R 12 , R 13 ); wherein R 2 is represented by the formula: —X-L-N + (R 11 , R 12 , R 13 ,) Z − ; —X-N + (R 11 , R 12 , R 13 ); CH 3 ; or Hydrogen; wherein V may be —S— or —Se— or —C— or —O— or —N; wherein Y may be —S—or —Se— or —C— or —O— or —N; wherein -L-N + (R 11 , R 12 , R 13 )Z − can be linked to V or Y if V or Y are —N or can be linked to V and Y if V and Y are both —N; wherein X is —CH 2 —, —OCH 2 —, —CH 2 O—, —SCH 2 — or —CH 2 S—; wherein L is a C 1 -C 4 straight alkane, alkene, thiol, ether, or amine; wherein R 11 , R 12 and R 13 are represented independently by C 1 -C 4 straight alkanes, alkenes, thiols, amines, ethers, alcohols; and wherein Z − is Cl − , Br − or I − .