Patent ID: 7833992

Claim:
A compound having Formula 107: wherein X comprises a short interfering RNA (siRNA) comprising 2′-fluoro pyrimidines and 2′-O-methyl purines; each W independently comprises a linker molecule selected from the group consisting of amide, phosphate, phosphate ester, phosphoramidate, thiophosphate ester linkage, and R 3 (CH 2 ) 2 O(CH 2 ) 2 (OCH 2 CH 2 ) n O(CH 2 ) 2 NHC(=0)—, where n is independently an integer from about 1 to about 20; Y comprises a linker molecule that can be present or absent; each R1, R2, R3, and R4 independently comprises O, OH, H, alkyl, alkylhalo, O-alkyl, O-alkylcyano, S, S-alkyl, S-alkylcyano, or N; and Cholesterol comprises cholesterol.