Patent ID: 7102009

Claim:
A compound of formula XI wherein R is selected from unsubstituted or substituted 9- or 10-membered fused nitrogen-containing heteroaryl selected from 6-indazolyl, 1-oxo-2,3-dihydro-1H-isoindol-4-yl, 2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl, and 4-oxo-3,4-dihydro-quinazolin-6-yl; wherein R 1 is selected from unsubstituted or substituted aryl, cycloalkyl, 5-6 membered heteroaryl and 9-10 membered bicyclic and 11-14 membered tricyclic heterocyclyl, wherein substituted R 1 is substituted with one or more substituents selected from halo, C 1-6 -alkyl, optionally substituted C 3-6 -cycloalkyl, optionally substituted phenyl, optionally substituted phenyl-C 1- C 4 -alkylenyl, C 1-2 -haloalkoxy, optionally substituted phenyloxy, optionally substituted 4-6 membered heterocyclyl-C 1- C 6 -alkyl, optionally substituted 4-6 membered heterocyclyl-C 2- C 4 -alkenyl, optionally substituted 4-6 membered heterocyclyl, optionally substituted 4-6 membered heterocyclyloxy, optionally substituted 4-6 membered heterocyclyl-C 1-4 -alkoxy, optionally substituted 4-6 membered heterocyclylsulfonyl, optionally substituted 4-6 membered heterocyclylamino, optionally substituted 4-6 membered heterocyclylcarbonyl, optionally substituted 4-6 membered heterocyclyl-C 1-4 -alkylcarbonyl, optionally substituted 4-6 membered heterocyclylcarbonyl-C 1-4 -alkyl, optionally substituted 4-6 membered heterocyclyl-C 1-4 -alkylcarbonylamino, optionally substituted 4-6 membered heterocyclyl-oxycarbonylamino, C 1-2 -haloalkyl, C 1-4 -aminoalkyl, nitro, amino, C 1-3 -alkylsulfonylamino, hydroxy, cyano, aminosulfonyl, C 1-2 -alkylsulfonyl, halosulfonyl, C 1-4 -alkylcarbonyl, amino-C 1-4 -alkylcarbonyl, C 1-3 -alkylamino-C 1-4 -alkylcarbonyl, C 1-3 -alkylamino-C 1-4 -alkylcarbonylamino, C 1-4 -alkoxycarbonyl-C 1-4 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkoxy, C 1-3 -alkylamino-C 1-3 -alkoxy-C 1-3 -alkoxy, C 1-4 -alkoxycarbonyl, C 1-4 -alkoxycarbonylamino-C 1-4 -alkyl, C 1-3 -alkylsulfonylamino-C 1-3 -alkoxy, C 1-4 -hydroxyalkyl, and C 1-4 -alkoxy; and wherein R e and R f are independently selected from H and C 1-2 -haloalkyl; and wherein R 7 is selected from H, C 1-3 -alkyl, optionally substituted phenyl, optionally substituted phenyl-C 1-3 -alkyl, 4-6 membered heterocyclyl, optionally substituted 4-6 membered heterocyclyl-C 1- C 3 -alkyl, C 1-3 -alkoxy-C 1-2 -alkyl and C 1-3 -alkoxy-C 1-3 -alkoxy-C 1-3 -alkyl; and pharmaceutically acceptable derivatives thereof.