Patent ID: 7884125

Claim:
A 1-substituted-7-azabicyclo[2.2.1]heptyl derivative represented by the structural formula (I): or the structural formula (II): wherein: R 0 is selected from the group consisting of hydrogen, benzyl, naphthylmethyl, C 3-4 alkenyl and C 1-8 alkyl, wherein said benzyl is optionally substituted with one to three substituents independently selected from the group consisting of halogen, C 1-4 alkyl, C 1-4 alkoxy, trifluoromethyl, trifluoromethoxy, dimethylaminoethoxy, dimethylaminopropoxy, morpholinoethoxy, phenoxy, phenoxymethyl, heteroaryl and heteroaryl-methyl; R 1 is hydrogen and R 2 is hydroxyl, or R 1 in combination with R 2 is oxo or imino; R 3 is a substituent selected from the group consisting of fluoro, chloro, bromo, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkylthio, cyano, phenyl, trifluoromethyl, trifluoromethoxy, amino, dimethylamino and tert-butylcarboxylate; and n is 0, 1 or 2; and Aryl is an arylene or heteroarylene divalent group, or a pharmaceutically acceptable salt thereof, or a stereochemically isomeric form thereof, or a solvate thereof.