Patent ID: 7321065

Claim:
A compound of formula I: or a stereoisomer, prodrug, pharmaceutically acceptable salt, hydrate, solvate, acid salt hydrate, N-oxide or isomorphic crystalline form thereof; wherein independently, R 1 and R 2 are: H, lower alkyl, cyclic alkyl, or benzyl; Y is —[CR 8 R 9 ]—; where R 8 is H, and R 9 is aryl optionally substituted with 1-3 substituents selected from the group consisting of lower alkyl, halo, hydroxy, and alkoxy; or benzyl wherein the phenyl portion thereof is optionally substituted with 1-3 substituents selected from the group consisting of lower alkyl, halo, hydroxy, and alkoxy; Z is: —[C(R) 2 ] n —, CHOR, O, S, NR, CONH, or NHCO; R 3 , R 4 , R 5 , and R 7 are: H, I, Br, Cl, F, CH 3 , CF 3 , CN, SR, OCH 3 , CH 2 CH 3 , or CH(CH 3 ) 2 ; R 6 is: OR, H, SH, F, CF 3 , lower alkyl, or N(R) 2 ; X is: O, S, SO, SO 2 , NR, C(R) 2 , -lower alkyl-O—, —O-lower alkyl-, COCH 2 O, or OCH 2 CO; R is H, lower alkyl, aryl optionally substituted with 1-3 substituents selected from the group consisting of lower alkyl, halo, hydroxy, and alkoxy; or benzyl wherein the phenyl portion thereof is optionally substituted with 1-3 substituents selected from the group consisting of lower alkyl, halo, hydroxy, and alkoxy; and n is 1 to 6.