Patent ID: 6914060

Claim:
A compound of formula I, or a pharmaceutically acceptable salt thereof: wherein: X 1 represents hydrogen, halogen, C 1-6 alkyl, trifluoromethyl or C 1-6 alkoxy; X 2 represents hydrogen or halogen; Y represents a chemical bond, an oxygen atom, or a —NH— linkage; Z represents a phenyl, pyridinyl, quinolinyl, isoquinolinyl, pyridazinyl, pyrimidinyl, pyrazinyl, furyl, benzofuryl, dibenzofuryl, thienyl, benzthienyl, pyrrolyl, indolyl, pyrazolyl, indazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, imidazolyl, benzimidazolyl, oxadiazolyl, thiadiazolyl, triazolyl or tetrazolyl group, which group is unsubstituted or substituted with one or more substituents selected from: halogen, cyano, nitro, C 1-6 alkyl, hydroxy, C 1-6 alkoxy, oxy, C 1-6 alkylsulphonyl, amino, aminocarbonyl, formyl, C 2-6 alkoxycarbonyl and —CR a ═NOR b ; R 1 represents a group selected from: C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-7 cycloalkyl, C 3-7 cycloalkyl(C 1-6 alkyl), indanyl, phenyl, phenyl(C 1-6 alkyl), azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, thiomorpholinyl, pyridinyl, quinolinyl, isoquinolinyl, pyridazinyl, pyrimidinyl, pyrazinyl, furyl, benzofuryl, dibenzofuryl, thienyl, benzthienyl, pyrrolyl, indolyl, pyrazolyl, indazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, imidazolyl, benzimidazolyl, oxadiazolyl, thiadiazolyl, triazolyl and tetrazolyl, which group is unsubstituted or substituted with one or more substituents selected from: C 1-6 alkyl, adamantyl, phenyl, halogen, C 1-6 haloalkyl, C 1-6 aminoalkyl, trifluoromethyl, hydroxy, C 1-6 alkoxy, aryloxy, keto, C 1-3 alkylenedioxy, nitro, cyano, carboxy, C 2-6 alkoxycarbonyl, C 2-6 alkoxycarbonyl(C 1-6 )alkyl, C 2-6 alkylcarbonyloxy, arylcarbonyloxy, aminocarbonyloxy, C 2-6 alkylcarbonyl, arylcarbonyl, C 1-6 alkylthio, C 1-6 alkylsulphinyl, C 1-6 alkylsulphonyl, phenylsulphonyl, —NR v R w , —NR v COR w , —NR v CO 2 R w , —NR v SO 2 R w , —CH 2 NR v SO 2 R w , —NHCONR v R w , —CONR v R w , —SO 2 NR v R w and —CH 2 SO 2 NR v R w , in which R v and R w independently represent hydrogen C 1-6 alkyl, phenyl or phenyl(C 1-6 )alkyl, or R 1 represents a group selected from: trifluoromethyl, —SO 2 R a , —SO 2 NR a R b , —COR a , —CO 2 R a and —CONR a R b ; and R a and R b independently represent hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-7 cycloalkyl, C 3-7 cycloalkyl(C 1-6 alkyl), indanyl, phenyl, or phenyl(C 1-6 alkyl).