Patent ID: 6919328

Claim:
A compound of Formula I, and pharmaceutically acceptable salts and solvates thereof: wherein R 1 is selected from the group consisting of C(O)C 1-6 alkenyl, C(O)NHR 2 , C(O)NHC 1-6 alkyl, C(O)NHC(O)R 2 , C(O)NHC(O)C 1-6 alkyl, C(O)NHC 1-6 alkenyl, C(O)NH 2 , C(S)NH 2 , C(S)NHC 1-6 alkyl, C(S)NHC 1-6 alkenyl, C(S)NHR 2 , C(S)NHC(O)R 2 , C(S)NHC(O)C 1-6 alkyl, R 2 is selected from the group consisting of Ar and heteroaryl, wherein heteroaryl is a mono- or bicyclic heteroaromatic radical containing from 6 to 10 carbon atoms of which 1-3 atoms are a heteroatom selected from the group consisting of S, O and N and wherein both Ar and heteroaryl are either unsubstituted at substituted with 1-4 groups independently selected from C 1-4 akyl, OC 1-4 alkyl, OH, CF 3 , OCF 3 , halo, NO 2 , SH, SC 1-4 alkyl, NH 2 , NHC 1-4 alkyl, N(C 1-4 alkyl)(C 1-4 alkyl), CN, C(O)OH, C(O)OC 1-4 alkyl, C(O)NHC 1-4 alkyl, NHC(O)C 1-4 alkyl, OC(O)C 1-4 alkyl, SOC 1-4 alkyl, SO 2 C 1-4 alkyl, SO 2 NHC 1-4 alkyl and SO 2 NH 2 ; X is selected from the group consisting of O, NH, NC 1-6 alkyl, and S; and n=1-4.