Patent ID: 8546322

Claim:
A compound of formula II: wherein R 2 is independently selected from the group consisting of H, C 1-8 alkyl, C 0-8 alkylaryl, carboxy-C 1-8 alkyl and carboxyC 0-8 alkylaryl; A is an amino acid moiety, <—NH—CHR 3 —CO—>, wherein R 3 indicates an amino acid side chain, —> and <— indicate the attachment sites to X 1 or R 1 and the rest of the molecule; p is 0; n is an integer of from 0 to 100; m is an integer of from 0 to 100; —(X 1 ) n — is a sequence of n independently selected amino acid units, —NH—R 4 —CO—, attached to A via an amide linkage to the amino terminus of the sequence and to R 1 via the carboxy terminus of the sequence, wherein each R 4 is independently an optionally substituted alkylene; R 1 is selected from the group consisting of C 1-8 alkoxy, aryl-C 0-8 alkoxy, heterocyclyl and amino, each of which is optionally substituted with from 1 to 3 substituents each independently selected from the group consisting of C 1-8 alkyl, aryl-C 0-8 alkyl and heterocyclyl; or a therapeutic agent; and —(X 2 ) m — is a sequence of m independently selected amino acid units, —NH—R 4 —CO—, attached to R 2 via the amino terminus of the sequence and the rest of the molecule via an amide linkage to the carboxy terminus of the sequence, wherein each R 4 is independently an optionally substituted alkylene or C 3-7 cycloalkylene.