Patent ID: 7601864

Claim:
A method for synthesizing 4,4-dihalogen-2-(dialkylamino) methylene-3-oxy-alkylbutyrate denoted by formula 3 and its derivatives comprising acts of: (a) providing N,N-dialkylamino-alkyl-acrylate denoted by formula 2 in a reaction vessel; (b) adding organic base, organic solvent and molecular sieves to the reaction vessel; (c) mixing N,N-dialkylamino-alkyl-acrylate, the organic base, the organic solvent and the molecular sieves; and (d) adding 2,2-dihalogen-acetyl-chloride denoted by formula 1 into the reaction vessel for allowing a synthetic reaction; wherein R 1 and R 2 are respectively selected from the group consisting of fluorine, chlorine and bromine; and R 3 , R 4 and R 5 are respectively selected from the group consisting of C 1 to C 5 alkyl group, C 1 to C 5 phenyl alkyl group and benzene group being selectively substituted with halogens; (e) performing solvent extraction after the step of (d) comprising adding water into the reaction vessel to allow contents of the reaction vessel to separate into two phases, wherein a lower phase is a water phase with the molecular sieves and an upper phase is an organic-solvent phase; removing the water phase with the molecular sieves and removing the organic solvent using a vacuum pump to obtain a crude product; and washing the crude product by an alkyl solvent with C 6 to C 9 ; and (f) filtering the alkyl solvent with the crude product to obtain a filtrate and drying the filtrate to obtain a product containing 4,4-dihalogen-2-(dialkylamino) methylene-3-oxy-alkylbutyrate and its derivatives.