Patent ID: 8114152

Claim:
An expandable intraluminal graft for use within a body passageway including a body member, intermediate compound, and biological agent, said body member having first and second ends and a wall surface disposed between said first and second ends defining a longitudinal axis of said body member, said body member having a first cross-sectional shape having a first cross-sectional area which permits intraluminal delivery of said body member into the body cavity, and a second expanded cross-sectional shape having a second cross-sectional area which is greater than said first cross-sectional area, said biological agent at least partially secured to said body member, said biological agent including one or more agents selected from the group consisting of Trapidil, GM-CSF, Trapidil derivative and GM-CSF derivative, said intermediate compound at least partially securing said biological agent to said body member, said intermediate compound including one or more compounds selected from the group consisting of a polymer and copolymer, said intermediate compound at least partially encapsulating at least a portion of said biological agent in said intermediate compound, between said body member and said intermediate compound, or combinations thereof, said intermediate compound at least partially delays delivery of said biological agent into said body passageway, said biological agent is at least partially releasably coated on said graft, said intermediate compound having a coating thickness of about 5,000 to 250,000 Å, said biological agent present in an amount of at least 1 μg and up to about 10 mg.