Patent ID: 7462622

Claim:
Compounds of formula (Ia) and stereoisomers and pharmaceutically acceptable salts thereof wherein R is aryl or heteroaryl and R may be substituted by 1 to 4 groups selected from: halogen, C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo C1-C6 alkoxy, —COR 4 , nitro, —NR 3 R 4 , cyano and R 5 ; R 1 is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo C1-C6 alkyl, halo C1-C6 alkoxy, halogen, NR 3 R 4 or cyano; R 2 is CHR 6 R 7 ; R 3 is hydrogen or C1-C6 alkyl; R 4 is hydrogen or C1-C6 alkyl; R 5 is C3-C7 cycloalkyl, which may contain one or more double bonds, aryl or a 5-6 membered heterocycle; wherein each R 5 may be substituted by one or more groups selected from: halogen, C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo C1-C6 alkoxy, C1-C6 dialkylamino, nitro or cyano; R 6 is hydrogen, C2-C6 alkenyl or C1-C6 alkyl, wherein R 6 may be substituted by one or more groups selected from: C1-C6 alkoxy and hydroxy; and R 7 is hydrogen, C2-C6 alkenyl or C1-C6 alkyl, wherein R 7 may be substituted by one or more groups selected from: C1-C6 alkoxy and hydroxyl.