Patent ID: 8414889

Claim:
A method of inhibiting growth and/or survival of a microbial pathogen in a patient, wherein said microbial pathogen is Candida albicans or Aspergillus fumigatus and has a cell wall containing β-1,3-glucan and β-1,6-glucan, said method comprising administering to the patient a composition comprising a monoclonal antibody that shows preferential binding to a β-1,3-glucan over a β-1,6-glucan, wherein the antibody is a human antibody, a chimeric antibody, a humanized antibody, a single chain antibody or a functional fragment thereof, and further wherein the antibody comprises heavy chain variable CDRs comprising the amino acid sequences of SEQ ID NOs: 4, 6, and 8, and light chain variable CDRs comprising the amino acid sequences of SEQ ID NOs: 10, 12 and 14.