Patent ID: 7199140

Claim:
A compound of Formula (II) or a salt, solvate, or prodrug thereof wherein A is pyridyl; R 3 is selected from OH, —O-C 1-6 alkyl, and NHR 6 ; each R 4 is independently from halo, —C 3-a F a , CN, NO 2 , NH 2 , C 1-6 alkyl, —OC 1-6 alkyl, —COOH, —C(O)OC 1-6 alkyl, OH, phenyl optionally substituted with C 1-6 alkyl, or —C(O)OC 1-6 alkyl, and R 5 —X 1 —; R 5 is selected from hydrogen, C 1-6 alkyl, —CH 3-a F a , phenyl, naphthyl, heterocyclyl, and C 3-7 cycloalkyl; wherein R 5 is optionally substituted with halo, C 1-6 alkyl, —CH 3-a F a , CN, NO 2 , NH 2 , COOH, or —C(O)OC 1-6 alkyl, and wherein each phenyl, naphthyl, or heterocyclyl ring in R 5 is optionally substituted with halo, CH 3-a F a , CN, NO 2 , NH 2 , C 1-6 alkyl, —OC 1-6 alkyl, COOH, —C(O)OC 1-6 alkyl, or OH; R 6 is selected from hydrogen, C 1-6 alkyl, OC 1-6 alkyl, SO 2 C 1-6 alkyl, and (CH 2 ) 0-3 OH; each X is a linker independently selected from —O—Z—, —O—Z—O—Z—, —OC(O)—Z—, —S—Z—, —SO—Z—, —SO 2 —Z—, —SO 2 N(R 7 )—Z—, and —S(O) 2 N(R 7 )C(O)—Z—; each X 1 is a linker independently selected from —Z—, —O—Z—, —O—Z—O—Z—, —C(O)O—Z—, —OC(O)—Z—, —S—Z—, —SO—Z—, —SO 2 —Z—, —N(R 7 )—Z—, —N(R 7 )SO 2 —Z—, —SO 2 N(R 7 )—Z—, —(CH 2 ) 1-4 —, —CH═CH—Z—, —C≡C—Z—, —N(R 7 )CO—Z—, —C(O)N(R 7 )—Z—, —C(O)N(R 7 )S(O) 2 —Z—, —S(O) 2 N(R 7 )C(O)—Z—, —C(O)—Z—, and a direct bond; each R 7 is independently selected from hydrogen, C 1-6 alkyl and —C 2-4 alkyl-O-C 1-4 alkyl; each Z is a direct bond; each Z 1 is independently selected from a direct bond, C 2-6 alkenylene and a group of the formula —(CH 2 ) p —C(R 6 ) 2 —(CH 2 ) q —; each a is independently 1, 2 or 3; p is 0, 1 or 2; q is 0, 1 or 2; and p+q<4.