Patent ID: 8748466

Claim:
A compound of Formula I or Formula II or a pharmaceutically acceptable salt thereof, wherein R 1 is (C 1 -C 3 )alkyl; R 2 is hydrogen or (C 1 -C 3 )alkyl; R 3 is hydrogen, (C 1 -C 3 )alkoxy, (C 1 -C 3 )alkyl, cyano, (C 1 -C 3 )haloalkoxy, (C 1 -C 3 )haloalkyl, halogen, or hydoxy; L is a bond, —(CH 2 ) n —, —(CH 2 ) n O(CH 2 ) p —, —(CH 2 ) n S(CH 2 ) p —, —(CH 2 ) n NR 4 (CH 2 ) p —, —(CH 2 ) n SO 2 NR 4 (CH 2 ) p —, —(CH 2 ) n NR 4 SO 2 (CH 2 ) p —, —(CH 2 ) n CONR 4 (CH 2 ) p —, or —(CH 2 ) n NR 4 CO(CH 2 ) p —; R 4 and R 5 are independently hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkylcarbonyl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkyl(C 1 -C 6 )alkyl, or formyl; n is 0, 1, 2, 3, or 4; p is 0, 1, 2, 3, or 4; R 6 is (C 1 -C 6 )alkoxy(C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxycarbonyl, (C 1 -C 6 )alkylcarbonyl, (C 1 -C 6 )alkyl-NR 4 —(C 1 -C 6 )alkyl, (C 1 -C 6 )alkylthio(C 1 -C 6 )alkyl, (C 1 -C 6 )alkylthiocarbonyl, (C 6 -C 12 )aryl, (C 6 -C 12 )aryloxy, (C 6 -C 12 )arylthio, (C 6 -C 12 )aryl-NR 4 —, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkyloxy, (C 3 -C 8 )cycloalkylthio, (C 3 -C 8 )cycloalkyl-NR 4 —, (C 5 -C 12 )heteroaryl, (C 5 -C 12 )heteroaryloxy, (C 5 -C 12 )heteroarylthio, (C 5 -C 12 )heteroaryl-NR 4 —, (C 3 -C 13 )heterocycle, (C 3 -C 13 )heterocycleoxy, (C 3 -C 13 )heterocyclethio, (C 3 -C 13 )heterocycle-NR 4 —, hydroxy(C 1 -C 10 )alkyl, mercapto(C 1 -C 6 )alkyl, (NR 4 R 5 )alkyl, or (NR 4 R 5 )carbonyl; and R 7 is absent, (C 6 -C 12 )aryl, (C 6 -C 12 )aryl(C 1 -C 6 )alkyl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkyl(C 1 -C 6 )alkyl, (C 5 -C 12 )heteroaryl, (C 5 -C 12 )heteroaryl(C 1 -C 6 )alkyl, (C 3 -C 13 )heterocycle, or (C 3 -C 13 )heterocycle(C 1 -C 6 )alkyl.