Patent ID: 8889683

Claim:
A compound of the formula I: or a pharmaceutically acceptable salt thereof, wherein: wherein X and Y represent carbon atoms and Z represents a nitrogen atom; each R 1 is H or is selected from the group consisting of: halo, CN, OH, C 1-6 alkyl, OC 1-6 alkyl, haloC 1-6 alkyl, OC 1-6 haloalkyl, S(O) x C 1-6 alkyl, and S(O) x C 1-6 haloalkyl, wherein x is 0, 1 or 2; R 2 represents OH, halo, C 1-6 alkyl, OC 1-6 alkyl, C 1-6 haloalkyl, OC 1-6 haloalkyl, NH 2 , NHC 1-6 alkyl and N(C 1-6 alkyl) 2 , the alkyl portions of NHC 1-6 alkyl and N(C 1-6 alkyl) 2 being optionally substituted with 1-3 halo atoms; R 3 and R 4 taken together with the N atom to which they are attached represent a 4-7 membered ring consisting of carbon atoms and 1 N atom, wherein the 4-7 membered ring is substituted with 1-3 groups selected from R b ; each R b is selected from the group consisting of: a) C 1-6 alkyl optionally substituted with 1-2 Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, O—C 1-6 Alkyl, O-Aryl, O-Heteroaryl, NH—C 1-6 Alkyl, NH-Aryl, and NH-Heteroaryl groups, the Aryl, Heteroaryl, Heterocyclyl and Alkyl portions being further optionally substituted with 1-3 C 1-3 alkyl, halo, OC 1-6 alkyl, C 1-6 haloalkyl and OC 1-6 haloalkyl groups; b) CO 2 C 1-6 Alkyl, CO 2 -Aryl, CO 2 -Heteroaryl, and CO 2 C 3-6 Cycloalkyl, each being optionally substituted with 1-2 C 1-3 alkyl, halo, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, O—C 1-6 Alkyl, NH—C 1-6 Alkyl, and NH-Aryl groups, the Aryl, Heteroaryl, and Heterocyclyl portions, and the alkyl portions of O—C 1-6 Alkyl and NH—C 1-6 Alkyl being further optionally substituted with 1-3 C 1-6 alkyl, halo, OC 1-6 alkyl, haloC 1-6 alkyl and OC 1-6 haloalkyl groups; c) Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, O—C 1-6 Alkyl, NH—C 1-6 Alkyl, and NH-Aryl, each being optionally substituted with 1-3 alkyl, halo, OC 1-6 alkyl, haloC 1-6 alkyl and OC 1-6 haloalkyl groups; or 2 R b groups are taken together and represent a fused phenyl ring, optionally substituted with 1-3 halo atoms or C 1-6 alkyl groups.