Patent ID: 8871179

Claim:
A method of measuring metabolism in a subject comprising the following steps: a) localizing to a tissue of interest a detectable amount of a radioactively labeled compound having the formula: wherein: A =(CH 2 ) y , O, S y =1, 2, 3, 4 cis and trans; R,R and S,S m =1-10 n =14-8 p =0-6 R =CH 3 X =radioactive label and wherein the cyclic or heterocyclic organic substituent —CH-A-CH— causes said compound to be metabolically trapped in said tissue; b) detecting a signal from said radioactively labeled compound in said tissue of interest within about 10 minutes to about 24 hours and; c) imaging said tissue of interest and; d) determining the rate of metabolism in said tissue of interest.