Patent ID: 7179874

Claim:
A biodegradable cationic polymer, which has amino groups in a backbone and side chains for delivering nucleic acids into a cell, and a formula (V a ) of the biodegradable cationic polymer shown as below: wherein U is (R 1 —O) d , in which R 1 is a C 2 –C 20 alkylene or substituted alkylene radical, d is an integer of 4 to 200, L is X is an amino acid group containing additional amino or amide group of the formula (II a ): in which R 8 is selected from the group consisting of —CH 2 CONH 2 —, —CH 2 CH 2 CONH 2 —, and —CH 2 CH 2 CH 2 NH 2 —, V is —COO—, Y is an amino group of the formula (VI a ): in which R 2 is hydrogen or C 1 –C 20 alkyl radical, R 3 and R 4 is the same C 1 –C 20 alkylene radical, Z is an another amino group of the formula (VII a ): in which R 5 is C 2 –C 20 alkylene radical, R 6 and R 7 are the same or different C 1 –C 5 alkyl radicals, m is an integer of 1 to 10, and n is an integer of 1 to 20.