Patent ID: 7115636

Claim:
A compound of the general formula (I) in which R 2 and R 3 are identical or different and represent hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, trifluoromethoxy, (C 1 –C 6 )-alkyl, (C 1 –C 6 )-alkoxy or a group of the formula in which R 5 , R 6 and R 7 are identical or different and in each case represent hydrogen or (C 1 –C 6 )-alkyl, which for its part can be substituted by one or two substituents selected from the group consisting of hydroxyl, halogen, cyano, trifluoromethyl and trifluoromethoxy, A represents a five- or six-membered heteroaryl linked via a C atom to the adjacent phenyl ring, R 1 represents the radical in which R 11 represents the side group of an amino acid, and the amino group in R 1 can optionally be mono- or polysubstituted by (C 1 –C 6 )alkyl, alkylcarbonyl, or phenyl, or R 1 represents a straight-chain or branched (C 1 –C 5 )-alkyl radical, which for its part can be substituted by one or more groups selected from phenyl, piperidinyl, pyridinyl, thiazolyl, thienyl, or a group in which R 12 and R 13 are identical or different and can represent hydrogen, (C 1 –C 6 )alkyl, alkylcarbonyl, an amino protective group, or phenyl, or R 1 represents a radical or R 1 represents a straight-chain or branched (C 1 –C 5 )-alkyl radical, which for its part is substituted by a group in which R 14 , R 15 , R 16 are identical or different and represent hydrogen or (C 1 –C 6 )alkyl and n can assume the values 2 or 3, or R 1 represents piperidinyl or the radical in which R 12 and R 13 have the meaning indicated above, n represents a number from 1 to 4 and the ring can be up to trisubstituted in an identical or different manner by halogen, (C 1 –C 6 )-alkyl, halogeno-(C 1 –C 6 )-alkyl, amino, or hydroxyl, R 4 represents tert-butyl, which is optionally up to trisubstituted, in an identical or different manner, by hydroxyl, fluorine or chlorine, or represents cyclopropyl or cyclobutyl, which are mono- to trisubstituted in an identical or independent manner by halogen or (C 1 –C 6 )-alkyl, (C 1 –C 6 )-alkyl optionally being substituted by hydroxyl, fluorine or chlorine, and in which X represents oxygen or sulphur, and in which nitrogen-containing heterocycles can also be present as N-oxides, or a tautomer, stereoisomer, or mixture of stereoisomers of said compound, or a pharmacologically tolerable salt of said compound, tautomer, stereoisomer, or mixture of stereoisomers.