Patent ID: 7736668

Claim:
A method for providing a therapeutic program that delays the delivery of verapamil followed by delivering verapamil to a patient, wherein the method comprises: administering orally to the patient a dosage form comprising (i) a drug composition comprising 0.05 ng to 1.0 g of verapamil and polyethylene oxide having a molecular weight of between 250,000 and 350,000; (ii) a push composition comprising 60 wt. % to 85 wt. % polymer comprising 2.0 wt. % to 15 wt. % hydroxypropylalkylcellulose having a molecular weight of between 9,000 and 25,000, and 15 wt. % to 30 wt. % of an osmagent capable of expanding and pushing the drug composition from the dosage form; (iii) a non-erodible and fluid-insoluble wall surrounding the drug and push compositions, the wall having a thickness of between 2 mils to 20 mils and comprising between 15 wt. % to 85 wt. % of a cellulose polymer; and (iv) an exit in the wall for delivery of verapamil from the dosage form, said exit having a diameter up to 30 mil, wherein the dosage form delays the delivery of verapamil up to 7 hours followed by delivery of verapamil over a prolonged period of time to provide the therapeutic program.