Patent ID: 7051906

Claim:
A pharmaceutical package comprising a closed polypropylene bottle in which is disposed a solution or gel, the solution or gel comprising a pharmaceutical product, wherein the solution or gel does not fill the bottle completely and some air is disposed in the bottle, and wherein the package is autoclaved by: a) placing the closed package into an autoclaving chamber; b) adjusting the temperature and the pressure in the chamber as a function of time in accordance to the prerequisites of the material of the package, wherein a counter pressure is generated in the chamber and wherein the counter pressure is regulated electronically by computer control; and wherein the package, after autoclaving at at least 121° C. and for at least 20 minutes, suffers no deformation, does not shrink, and does not explode, and where the package retains a sufficiently high squeezability to dispense one drop at a time the solution or gel.