Patent ID: 8329706

Claim:
A compound of formula (I) wherein Y represents CH 2 , CHR 1 , or CR 1 R 2 ; wherein R 1 and R 2 independently represent (C 1-4 )alkyl; R 3 represents Ar 1 or Ar 3 —Z—Ar 2 —* wherein the asterisk indicates the bond that is attached to the rest of the molecule; wherein Ar 1 represents aryl or heteroaryl, wherein the aryl or heteroaryl is independently unsubstituted, or mono-, di-, or tri-substituted, wherein the substituents are independently selected from the group consisting of (C 1-4 )alkyl, (C 1-4 )alkoxy, halogen, (C 1-3 )fluoroalkyl, (C 1-3 )fluoroalkoxy, (C 1-3 )fluoroalkyl-thio-, and (C 3-6 ) cycloalkyl-(C 1-4 )alkoxy; Ar 2 represents phenyl or 5- to 6-membered heteroaryl; Z represents a bond, O, or —CH 2 —O—* wherein the asterisk indicates the bond that is attached to Ar 2 ; Ar 3 represents phenyl or 5- to 6-membered heteroaryl wherein the phenyl or 5- to 6-membered heteroaryl is independently unsubstituted, or mono-, di-, or tri-substituted, wherein the substituents are independently selected from the group consisting of (C 1-4 )alkyl, (C 1-4 )alkoxy, halogen, (C 1-3 )fluoroalkyl, and (C 1-3 ) fluoroalkoxy; and R 4 represents aryl or heteroaryl, wherein the aryl or heteroaryl is independently mono-, di-, or tri-substituted, wherein the substituents are independently selected from the group consisting of (C 1-4 )alkyl, (C 1-4 )alkoxy, halogen, (C 1-3 )fluoroalkyl, (C 1-3 )fluoroalkoxy, hydroxy-(C 1 4alkoxy, and (C 1-4 )alkoxy-(C 1-4 )alkoxy; wherein, in the specific case wherein said aryl or heteroaryl is a bicyclic ring, the aryl or heteroaryl may also be unsubstituted; with the exception of the following compounds: 2-(2-bromophenyl)-3-[(4-methoxyphenyl)methyl]-4-oxazolidinone; 2-(2-bromophenyl)-3-{[4-(trifluoromethyl)phenyl]methyl}-4-oxazolidinone; 2-(2-bromophenyl)-3-(phenylmethyl)-4-oxazolidinone; and 2-(4-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-5-methyl-4-oxazolidinone; in a free or a pharmaceutically acceptable salt.