Patent ID: 7939261

Claim:
A method for determining the likelihood of breast cancer recurrence or response to hormonal therapy in a human subject comprising: (a) measuring the expression levels of the RNA transcripts of SURV, Ki.67, MYBL2, CCNB1, STK15, CTSL2, and STMY3, or their expression products, in a biological sample containing tumor cells obtained from said subject; (b) calculating a recurrence score (RS) for said subject by weighting the measured expression levels of gene subsets by contribution to breast cancer recurrence, wherein the gene subsets comprise: (i) a proliferation subset: SURV, Ki.67, MYBL2, CCNB1, and STK15; and (ii) an invasion subset: CTSL2, and STMY3; and (c) creating a report providing the RS; wherein the RS is indicative of the likelihood of breast cancer recurrence in said subject or response of said subject to hormonal therapy.