Patent ID: 8685959

Claim:
A compound having formula (I): or a pharmaceutically acceptable salt thereof wherein: the dashed bond indicates a single or double bond; R 1 is a member selected from the group consisting of hydrogen, C 1-8 alkyl, C 1-8 haloalkyl, C 3-8 cycloalkyl, and halogen; R 2 is a member selected from the group consisting of hydrogen, C 1-8 alkyl, C 3 cycloalkyl, C 1-8 haloalkyl, halogen, CN, and C 1-8 alkoxy; R 3 is a member selected from the group consisting of H, C 1-4 lower alkyl and C 1-4 haloalkyl; R 4 is a member selected from the group consisting of H, C 1-8 alkyl, C 1-8 hydroxyalkyl, and C 1-8 hydroxyalkyl; the subscripts n are each independently selected from the group consisting of 0, 1, 2 and 3; the subscript m is 1; each A is independently C or N, and at least one A is N; B is C(O), Q, W, and Z are independently C, CH, or N with the exception that Q and W may not both be N in the same compound; X is C, CH or N; Y is N; R 5 and R 6 are each independently absent or are a member selected from the group consisting of H, OH, NH 2 ,halogen, C 1-8 alkyl, C 1-8 hydroxyalkyl, and C 1-8 alkyl- NH 2 ; R 7 is absent or a member selected from the group consisting of H, halogen, C 1-8 alkyl and C 1-8 haloalkyl; R 8 is absent or a member selected from the group consisting of H, OH, NH 2 , NHR a , CN, C 1-4 aminoalkyl, C 1-4 hydroxyalkyl and C 1-4 alkyl; R 9 is absent or a member selected from the group consisting of H, CF 3 ,C 1-4 alkyl, CN, and â€”CO 2 R a ; R 10 is absent or a member selected from the group consisting of H, CF 3 , C 1- 4 alkyl and CN; and wherein R a is selected from the group consisting of H, and C 1-8 alkyl.