Patent ID: 8268310

Claim:
An isolated anti-Factor D antibody, or a binding fragment thereof, wherein said antibody or said binding fragment comprises the Complementarity Determining Regions (CDRs) of antibody 20D12 light and heavy chain variable domains (SEQ ID NOS: 1 and 2, respectively), and wherein the light chain CDR1 sequence comprises amino acid residues 24-34, the light chain CDR2 sequence comprises amino acid residues 50-56, and the light chain CDR3 sequence comprises amino acid residues 89-97 of SEQ ID NO: 1, and the heavy chain CDR1 sequence comprises amino acid residues 31-35, the heavy chain CDR2 sequence comprises amino acid residues 50-65, and the heavy chain CDR3 sequence comprises amino acid residues 95-102 of SEQ ID NO: 2.