Patent ID: 8030480

Claim:
A process of preparing an iron sucrose complex having a molecular weight between 34,000 and 60,000 daltons, comprising the steps of: (a) reacting a ferric salt with a base in a solvent at a pH between 4.0 and 6.0 to form ferric oxyhydroxide and isolating the ferric oxyhydroxide as a slurry; (b) adding the ferric oxyhydroxide slurry to an aqueous solution of sucrose and adjusting the pH of the reaction mixture to between 11.3 and 12.0 with an aqueous solution of an inorganic base at a temperature between 15° C. and 40° C. to form a reaction mixture; (c) heating the reaction mixture to a temperature between 85° C. and 100° C., adjusting the pH of the reaction mixture to between 9.75 and 10.0 and stirring the reaction mixture for a period of time from 2 to 3 hours to form the iron sucrose complex; and (d) isolating the iron sucrose complex from the reaction mixture by adjusting the pH of the reaction mixture between 12.0 and 12.5, concentrating the reaction mixture, adding the concentrated reaction mixture to an organic solvent or adding an organic solvent to the concentrated reaction mixture, and filtering.