Patent ID: 7642083

Claim:
A recombinant microbe comprising: (A) a 3-deoxy-D-arabino-heptulosonic acid-7-phosphate (DAHP) synthase enzyme that is insensitive to feedback inhibition by aromatic amino acids encoded by an aroF FBR gene from E. coli, (B) a 3-dehydroquinate (DHQ) synthase enzyme encoded by an aroB gene from E. coli , and (C) a shikimate dehydrogenase enzyme encoded by an aroE gene from E. coli, wherein (I) the gene of at least one of said enzymes is recombinant, (II) the microbe's DNA that encodes dehydroquinate dehydratase has been inactivated so that the recombinant microbe does not cause dehydration of 3-dehydroquinate to dehydroshikimate, and (III) the recombinant microbe is capable of producing quinic acid from a carbon source by a synthesis scheme that uses all three of said enzymes.