Patent ID: 7714012

Claim:
A compound comprising the structure Q1: wherein R 1 , R 2 , R 3 , R 4 and R 5 are each independently —H, hydroxy, amino, cyano, halo, nitro, mercapto, phosphate, sulfonic acid, sulfonate or substituted or unsubstituted versions of C 1 -C 15 -alkyl, C 2 -C 15 -alkenyl, C 2 -C 15 -alkynyl, C 6 -C 15 -aryl, C 7 -C 15 -aralkyl, C 1 -C 15 -heteroaryl, C 2 -C 15 -heteroaralkyl, C 1 -C 15 -acyl, C 1 -C 15 -alkoxy, C 2 -C 15 -alkenyloxy, C 2 -C 15 -alkynyloxy, C 6 -C 15 -aryloxy, C 7 -C 15 -aralkoxy, C 1 -C 15 -heteroaryloxy, C 2 -C 15 -heteroaralkyloxy, C 1 -C 15 -acyloxy, C 1 -C 15 -alkylamino, C 2 -C 15 -alkenylamino, C 2 -C 15 -alkynylamino, C 6 -C 15 -arylamino, C 7 -C 15 -aralkylamino, C 1 -C 15 -heteroarylamino, C 2 -C 15 -heteroaralkylamino, C 2 -C 15 -amido, C 1 -C 15 -alkylthio, C 6 -C 15 -arylthio, C 7 -C 15 -aralkylthio, C 1 -C 15 -heteroarylthio, C 2 -C 15 -heteroaralkylthio, C 1 -C 15 -acylthio, or C 0 -C 15 -silyl; X is selected from the group consisting of —H, —OH, ═O, ═NR′, and ═S, wherein R′ is —H, —OH, —NH 2 , or NHR″, wherein R″ is a substituted or unsubstituted version of C 1 -C 15 -alkyl or C 6 -C 15 -aryl; A, B, C and D, each independently signifies a single- or double-bond, provided that (1) when D is a double-bond, R 4 is absent, (2) when C is a double bond, X is ═O, ═NR′ or ═S, (3) when C is a single bond, X is —H or —OH, (4) when A is a double bond B is a single bond, and (5) when B is a double bond A is a single bond; n is 0, 1, or an integer greater than 1; the ketone group shown in the above structure may replaced by its enol tautomer, and pharmaceutically acceptable salts, hydrates, tautomers and optical isomers thereof.