Patent ID: 8338400

Claim:
A method for providing testosterone replacement therapy to a female in need thereof, which method comprises the daily and precise administering to a female of between 200 to 240 mg of a formulation that includes about 1% testosterone, an alkanol in an amount between about 5 to 80%, a polyalcohol in an amount between about 1% to 30%, and a permeation enhancer in an amount between about 1 to 30% with the formulation being substantially free of long-chain fatty alcohol, long-chain fatty acid and long-chain fatty ester compounds in order to accurately deliver between 2 to 2.4 mg of testosterone to provide an effective replacement amount of testosterone and achieve decreases in or alleviation of at least one of the clinical symptoms resulting from low testosterone levels in the female while avoiding irritation from such compounds during administration and use of the formulation.