Patent ID: 7105178

Claim:
A cardiotonic composition comprising micronized digoxin wherein the micronized digoxin is such that at least 50% of the particles are less than 15 microns, at least 90% of the particles are less than 25 microns, at least 99% of the particles are less than 50 microns, and about 13% of the particles are from 10 to 50 microns, hydrophilic polymer(s) and optionally pharmaceutically acceptable excipient(s) in the form of a tablet that releases not more than 50% digoxin in 5 minutes and at least 85% digoxin in 60 minutes when tested in vitro in United States Pharmacopoeia Type I Dissolution apparatus using 500 ml of 0.1N HCl at rpm of 120 for 60 minutes at 37° C.