Patent ID: 7423156

Claim:
A compound of Formula (I) wherein Q is O or S; A is a linker selected from wherein p is 1 or 2 and wherein m is 0 and n is 1, 2, 3, or 4, or m is 1 and n is 1, 2, or 3, and wherein said linker is optionally substituted by one or two R 8 groups; R 1 and R 2 are independently selected from hydrogen, halo, (C 1 -C 6 )alkyl, and (C 1 -C 6 )alkoxy; R 3 is selected from hydrogen, (C 1 -C 6 )alkyl optionally substituted by hydroxy, and phenyl optionally substituted with (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, or halo; R 4 is selected from hydrogen, nitro, and (C 1 -C 6 )alkyl; or R 3 and R 4 may, when taken together with the carbon atoms to which they are attached, form a benzene ring optionally substituted with up to two substituents selected from halo, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, nitro, cyano, (C 1 -C 6 )haloalkyl, (C 1 -C 6 )haloalkoxy, aminocarbonyl, (C 1 -C 6 )alkylaminocarbonyl, bis[(C 1 -C 6 )alkyl]aminocarbonyl, aminosulfonyl, (C 1 -C 6 )alkylaminosulfonyl, bis[(C 1 -C 6 )alkyl]aminosulfonyl, (C 1 -C 6 )alkylcarbonylamino, (C 1 -C 6 )alkylsulfonylamino, and hydroxy-(C 2 -C 6 )alkylaminocarbonyl, and when two of said benzene ring substituents are (C 1 -C 6 )alkyl and are attached to adjacent carbon atoms of the benzene ring, they may be joined together to form a 5-7-membered carbocyclic ring; R 6 is hydrogen; R 7 is hydrogen or (C 1 -C 6 )alkyl optionally substituted with (C 1 -C 6 )alkoxy, bis[(C 1 -C 3 )alkyl]amino or phenyl optionally substituted with halo, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, or cyano; or R 6 and R 7 are both (C 1 -C 6 )alkyl; or R 6 and R 7 may form, together with the carbon atom to which they are attached, a 3- to 5-membered carbocyclic ring, R 8 is (C 1 -C 6 )alkyl; or a pharmaceutically acceptable salts or ester thereof.