Patent ID: 8247407

Claim:
A method for the treatment of non-insulin-dependent diabetes, comprising administering to a patient having non-insulin-dependent diabetes a pharmaceutical composition comprising a therapeutically effective amount of a compound of general formula (I): where: R 1 is selected from the group consisting of an optionally substituted alkyl, an optionally substituted oxyalkyl, an optionally substituted cycloalkyl, an optionally substituted heterocyclil, and an optionally substituted aryl, wherein the optional substituent(s) may be one or more members selected from lower alkyl, halogen, oxyalkyl, hydroxyl, and amino; R 2 is —H, or —CH 2 NR′R″; where R′ and R″, independently of each other, are each selected from the group consisting of hydrogen, optionally substituted alkene, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted alkoxy, optionally substituted heterocyclil, and optionally substituted aryl, or where R′ and R″, along with the nitrogen atom with which they are bound, form guanidyl or optionally substituted azaheterocyclil; R 3 is an alkoxy group, or —OH; or R 2 and R 3 form together an optionally substituted oxazine cycle; R 4 is selected from the group consisting of hydrogen, halogen, cyano, NO 2 , trifluoromethyl, optionally substituted aryl and optionally substituted heterocyclil; A represents —S—, —SO—, —SO 2 —, and n =0-1; B represents —(CH 2 ) k —R 5 , where k =0-2, and where R 5 is an optionally substituted aryl, an optionally substituted alkyl, an optionally substituted oxyalkyl, or an optionally substituted heterocyclil, or where R 5 represents a substituent of the type: where Rn 1 , and Rn 2 are defined according to the definitions of the substituents R′ and R″ above; or hydrates and/or pharmaceutically acceptable salts thereof.