Patent ID: 8722633

Claim:
A compound represented by structural formula (I): or a pharmaceutiacally acceptable salt thereof, wherein: ring A is a 5-, 6- or 7-membered heterocyclyl; X is O, NR 5 , S, S(O) or S(O) 2 ; V is hydrogen, halo or —OR 1b ; R 1 , R 1 a and R 1b are independently selected from the group consisting of hydrogen, C 1 - 6 alkyl, C 6-10 aryl-— 1-4 alkyl, —C(O)C 6-10 aryl and —C(O)C 1-6 alkyl1kyl; R 2 and R 2 a, for each occurrence, are independently selected from the group consisting of halo, hydroxy, cyano, carboxy, C 1-6 alkyl, C 1-6 alkoxy and C 3-10 cycloalkyl; R 3 is halo, hydroxy, C 1-6 alkyl, haloC 1-6 alkyl, C 3-10 cycloalkyl, C 1-6 alkoxy, haloC 1-3 alkoxy or a 3- to 7-membered heterocyclyl; R 4 is a C 1-6 alkyl, haloC 1-6 alkyl, C 3-10 cycloalkyl, C 6-10 aryl, or a 5- to 10-membered heteroaryl; R 5 is hydrogen, C 1-6 alkyl, C 3-10 cycloalkyl, or C 1-6 alkanoyl; or R 4 and R 5 together with the nitrogen to which they are attached form a 3- to 7-membered heterocyclyl; n is 0, 1, 2, or 3; and q is 0, 1, or 2.