Patent ID: 8367836

Claim:
A compound having a structure according to Formula (Ia): or a salt or solvate or single stereoisomer or mixture of stereoisomers thereof, wherein m is an integer selected from 0 to 4; n is an integer selected from 0 to 3; p is an integer selected from 0 to 4; ring A is a member selected from substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; Cy is a member selected from substituted or unsubstituted (C 3 -C 10 )cycloalkyl, substituted or unsubstituted 3- to 10-membered heterocycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; each R 1 and each R 2 is a member independently selected from H, substituted or unsubstituted (C 1 -C 10 )alkyl, substituted or unsubstituted 2- to 10-membered heteroalkyl, substituted or unsubstituted (C 3 -C 10 )cycloalkyl, substituted or unsubstituted 3- to 10-membered heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, nitro, CN, halogen, OR 12 , SR 12 , NR 12 R 13 , C(O)R 14 , C(O)NR 12 R 13 , OC(O)NR 12 R 13 , C(O)OR 12 , NR 15 C(O)R 14 , NR 15 C(O)OR 12 , NR 15 C(O)NR 12 R 13 , NR 15 C(S)NR 12 R 13 , NR 15 S(O) 2 R 14 , S(O) 2 NR 12 R 13 and S(O) z R 14 , wherein z is 1 or 2; R 12 , R 13 and R 15 are members independently selected from H, acyl, substituted or unsubstituted (C 1 -C 10 )alkyl, substituted or unsubstituted 2- to 10-membered heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted (C 3 -C 10 )cycloalkyl, substituted or unsubstituted 3- to 10-membered heterocycloalkyl; and R 14 is a member independently selected from substituted or unsubstituted (C 1 -C 10 )alkyl, substituted or unsubstituted 2- to 10-membered heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted (C 3 -C 10 )cycloalkyl, substituted or unsubstituted 3- to 10-membered heterocycloalkyl, wherein R 12 and R 13 , together with the nitrogen atoms to which they are attached, are optionally joined to form a 4- to 7-membered ring, and wherein two adjacent R 1 , together with the atoms to which they are attached, are optionally joined to form a 5- to 7-membered ring, and wherein two adjacent R 2 , together with the atoms to which they are attached, are optionally joined to form a 5- to 7-membered ring; R 3 , R 4 and R 5 are members independently selected from H, substituted or unsubstituted (C 1 -C 4 )alkyl, halogen and CN; and R 6 is a member selected from H and substituted or unsubstituted (C 1 -C 4 )alkyl.