Patent ID: 7220770

Claim:
A compound of Formula I wherein R 1 and R 2 are independently selected from aryl, cycloalkyl, cycloalkenyl and heterocyclo, wherein R 1 and R 2 are optionally substituted at a substitutable position with one or more radicals independently selected from alkylsulfonyl, aminosulfonyl, haloalkylsulfonyl, halo, alkylthio, alkyl, cyano, carboxyl, alkoxycarbonyl, haloalkyl, hydroxyl, alkoxy, hydroxyalkyl, alkoxyalkyl, haloalicoxy, amino, alkylarnino, arylamino and nitro; wherein R 3 is a radical selected from hydrido, alkyl, haloalkyl, aralkyl, heterocycloalkyl, acyl, cyano, alkoxy, alkylthio, alkylthioalkyl, alkylsulfonyl, cycloalkylthio, cycloalkylthioalkyl, cycloalkylsulfonyl, cycloalsufonylalkyl, cycloalkyloxy, cycloalkyloxyalkyl, haloalkylsulfonyl, arylsulfonyl, halo, hydroxyalkyl, alkoxyalkyl, alkylcarbonyl, arylcarbonyl, aralkylcarbonyl, heterocycloalkylcarbonyl, cyanoalkyl, azidoalkyl, aminoalkyl, alkylaminoalkyl, Narylaminoalkyl, N-alkyl-N-arylaminoalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxycarbonyl, haloalkylcarbonyl, carboxyl, aminocarbonyl, alkylaminocarbonyl, alkylaminocarbonylalkyl, heteroarylalkoxyalkyl, heteroaryloxyalkyl, heteroarylthioalkyl, aralkoxy, aralkylthio, heteroaralkoxy, heteroaralkylthio, heteroarylalkylthioalkyl, heteroaryloxy, heteroarylthio, arylthioalkyl, aryloxyalkyl, axylthio, aryloxy, aralkylthioalkyl, aralkoxyalkyl, aryl and heterocyclo; wherein R 4 is a radical selected from hydrido, alkyl and fluoro; wherein R 5 is selected from hydroxyl and ailkoxy; and wherein R 6 is hydrido; or wherein R 5 and R 6 together form a double bond; provided at least one of R 1 and R 2 is aryl substituted with alkylsulfonyl, haloalkylsulfonyl or aminosulfonyl; or a pharmaceutically-acceptable salt thereof.