Patent ID: 8759537

Claim:
A compound of formula I in which R 1 and R 2 independently represent halo; W represents —C(O)—, or —C(O)O—, which groups are bound to the nitrogen of the —NH— moiety via the carbon atom; M represents —C 1-6 alkyl, or —C 3-7 cycloalkyl, both of which groups are optionally substituted by one or more groups selected from —F, —OH, —CN, —NH 2 , —NH(C 1-2 alkyl), —N(C 1-2 alkyl) 2 , —OC 1-3 alkyl, —C 1-5 alkyl, or —C 3-4 cycloalkyl, in which latter three groups the alkyl or cycloalkyl groups are optionally substituted by one or more fluorine atoms; or oxetanyl-, tetrahydrofuranyl-, tetrahydropyranyl-, azetidinyl-, pyrrolidinyl-, or piperidinyl-, all of which groups are optionally substituted by one or more substituents selected from fluoro, —CN, or —C 1-3 alkyl, which latter alkyl group is optionally substituted by one or more fluorine atoms; or phenyl-, pyridyl-, thienyl-, pyrrolyl-, pyrazolyl-, imidazolyl-, thiazolyl-, oxazolyl-, or isoxazolyl-, all of which groups are optionally substituted by one or more substituents selected from halo, —CN or —C 1-3 alkyl, which latter alkyl group is optionally further substituted by one or more fluorine atoms; R 8 represents —H, halogen, or —C 1-3 alkyl, which latter alkyl group is optionally substituted by one or more fluorine atoms; R 6 represents —H, —C 1-5 alkyl, or —C 3-5 cycloalkyl-C 0-2 alkyl, in which latter two groups the alkyl or cycloalkyl fragments are optionally substituted by one or more fluorine atoms; R 7 represents halo, C 1-5 alkyl-O—, C 3-7 cycloalkyl-C 0-2 alkyl-O—, or 4-7-membered heterocycloalkyl-C 0-2 alkyl-O—, in which latter three groups the alkyl, cycloalkyl or heterocycloalkyl fragments are optionally substituted by one or more substituents selected from —F and —OC 1-3 alkyl which latter alkyl group is optionally further substituted by one or more fluorine atoms; represents C 1-8 alkyl-, phenyl-, indanyl-, naphthyl-, 1,2,3,4-tetrahydronaphthyl-, pyridyl-, thienyl-, benzothienyl-, pyrrolyl-, indolyl-, pyrazolyl-, indazolyl-, thiazolyl-, benzothiazolyl-, oxazolyl-, benzooxazolyl-, isoxazolyl-, benzisoxazolyl-, phenyl-C 1-3 alkyl-, thienyl-C 1-3 alkyl-, pyridyl-C 1-3 alkyl-, C 3-7 cycloalkyl-C 0-3 alkyl-, oxetanyl-C 0-3 alkyl-, tetrahydrofuranyl-C 0-3 alkyl, or tetrahydropyranyl-C 0-3 alkyl, in which groups the alkyl-, cycloalkyl- and heterocycloalkyl fragments are optionally substituted by one or more substituents selected from R 9a and the aryl and heteroaryl fragments are optionally substituted by one or more substituents selected from R 9b ; each R 9a independently represents —F, —Cl, or —C 1-3 alkyl which is optionally substituted by one or more substituents selected from —F, or —OC 1-3 alkyl; each R 9b represents independently -halo, —CN; or —C 1-3 alkyl which is optionally substituted by one or more fluorine atoms; or a salt thereof.