Patent ID: 7169926

Claim:
A compound of the formula: wherein Q is CO or C═NR 5 ; Z is nitrogen; R 1 is selected from the group consisting of halo, perhalo(C 1-10 )alkyl, amino, cyano, thio, (C 1-10 )alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, carbonyl (C 1-3 )alkyl, thiocarbonyl (C 1-3 )alkyl, sulfonyl (C 1-3 )alkyl, sulfinyl (C 1-3 )alkyl, imino (C 1-3 )alkyl, hydroxy, alkoxy, aryloxy, heteroaryloxy, carbonyl group, imino group, sulfonyl group and sulfinyl group, each substituted or unsubstituted; R 2 is hydrogen or is selected from the group consisting of (C 1-6 )alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, each substituted or unsubstituted; R 3 and R 4 are taken together to form a substituted or unsubstituted 4, 5, 6 or 7 membered ring; R 5 is hydrogen or is selected from the group consisting of (C 1-10 )alkyl, cycloalkyl, heterocycloalkyl, arylalkyl, heteroarylalkyl, bicycloaryl, and heterobicycloaryl, each substituted or unsubstituted; R 6 is hydrogen or is selected from the group consisting of (C 1-10 )alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, each substituted or unsubstituted; L is a substituent linking the ring nitrogen to X that is 1, 2 or 3 atoms in length as measured from the ring nitrogen to X; connecting the M substituent to the carbon atom alpha to the L substituent; and X is selected from the group consisting of (C 1-10 )alkyl, (C 3-12 )cycloalkyl, hetero(C 3-12 )cycloalkyl, aryl(C 1-10 )alkyl, heteroaryl(C 1-5 )alkyl, (C 9-12 )bicycloaryl, hetero(C 4-12 )bicycloaryl, carbonyl (C 1-3 )alkyl, thiocarbonyl (C 1-3 )alkyl, sulfonyl (C 1-3 )alkyl, sulfinyl (C 1-3 )alkyl, imino (C 1-3 )alkyl, amino, aryl, heteroaryl, hydroxy, alkoxy, aryloxy, heteroaryloxy, carbonyl group, cyano, imino group, sulfonyl group and sulfinyl group, each substituted or unsubstituted; with the provisos that (i) R 1 is not —SCH 3 when Q is CO, Z is N, LX is —CH 2 —OEt, R 2 is H and R 3 and R 4 are taken together to form indole, and (ii) R 1 is not —CH 3 or phenyl when Q is CO, Z is N, LX is —CH 2 —Ph, R 2 is phenyl and R 3 and R 4 are taken together to form pyridine.