Patent ID: 7674244

Claim:
A system for injection of a fluid into a body, comprising: a source of a first fluid; a source of a second fluid, the first fluid being less toxic than the second fluid; at least one pressurizing system in operative connection with the source of the first fluid and with the source of the second fluid; at least one controller in operative connection with the pressurizing system; and at least a first sensor in communicative connection with the controller, the first sensor being adapted to transmit a signal of a detected change in fluid level in tissue indicative of extravasation to the controller, the controller being adapted to cause injection of the first fluid into the body to determine if extravasation of the first fluid occurs using the sensor in an administration phase before injection of the second fluid, wherein the first sensor is based on electromagnetic energy and to measure extravasation of the first fluid in at least a first volume of the tissue, wherein the at least one controller includes an extravasation protocol associated therewith, the extravasation protocol comprising a first protocol wherein at least one of operation of the first sensor or application of a detection model is set to measure extravasation of the first fluid in the administration phase during injection of the first fluid and a second protocol wherein at least one of operation of the first sensor or application of the detection model is set to measure extravasation of the second fluid during subsequent injection of the second fluid, wherein settings in the first protocol are different than settings in the second protocol.