Patent ID: 7429680

Claim:
A method for the synthesis of severely sterically hindered secondary aminoether alcohols of the formula wherein R 1 and R 2 are each selected from the group consisting of alkyl, hydroxylalkyl radicals having 1 to 4 carbon atoms or in combination with the carbon atom to which they are attached they form a cycloalkyl group having 3 to 8 carbon atoms, and R 3 is selected from the group consisting of hydrogen, alkyl, hydroxyalkyl radicals having 1 to 4 carbon atoms, and mixtures thereof, and R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and R 11 are the same or different and are selected from the group consisting of hydrogen, alkyl and hydroxyalkyl radicals having 1 to 4 carbons provided that at least one of R 4 or R 5 bonded to the carbon atom directly bonded to the nitrogen atom is an alkyl or hydroxyalkyl radical when R 3 is hydrogen, the process involving reacting an organic carboxylic acid or salt of a carboxylic acid of the formula wherein R 12 is selected from the group consisting of alkyl radicals having 1 to 4 carbon atoms, aryl radicals bearing hydrogen or one or more C 1 -C 10 alkyl groups substituted thereon, and mixtures thereof, and Y is selected from the group consisting of hydrogen, alkali metal, ammonium, and mixtures thereof, with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide, or a mixed sulfuryl amide halide of the formula R 14 SO 2 X, SO 2 X 2 , R 14 OSO 2 X, or R 2 14,14′NSO 2 X wherein X is selected from the group consisting of F, Cl, Br, I, and mixtures thereof, and R 14 and R 14′ are the same or different and each is selected from the group consisting of alkyl radicals having 1 to 4 carbon atoms, haloalkyl radicals of the formula C n H (2n+1)−w Z W wherein n is 1 to 4, Z is selected from the group consisting of F, Cl, Br, I, and mixtures thereof, and w ranges from 1 to 5, and aryl radicals wherein R 15 , R 16 , R 17 , R 18 , and R 19 are the same or different and are selected from hydrogen and alkyl radicals having 1 to 20 carbon atoms, and mixtures thereof, to yield acyl sulfonate material of the general formula which is then reacted with a dioxane of the formula wherein R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , and R 11 are the same or different and are selected from hydrogen, alkyl and hydroxyalkyl radicals having 1 to 4 carbons to yield which is then aminated with an alkylamine of the formula wherein R 1 , R 2 , and R 3 are as previously defined to yield which is then hydrolyzed with base to yield