Patent ID: 8518995

Claim:
A method for treatment of irritable bowel syndrome or amelioration of a symptom thereof in a subject, comprising administering to said subject an effective amount of a compound of formula I: wherein n is an integer selected from 1 or 2; X is a C 1 -C 6 alkylene group; Y is —N(R) 2 wherein each R is independently selected from hydrogen or C 1 -C 6 alkyl, or two R along with the nitrogen bound thereto join together to form a 3 to 7 membered heterocyclic ring optionally containing an oxygen atom; and * represents a carbon atom in an R configuration, an S configuration, or a mixture thereof, a metabolite thereof, a prodrug thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein the administration of the compound reduces the incidence of one or more side effects in the subject compared to the number of such incidences, which would have been observed in the subject with the administration of terbutaline, ritodrine, or meluadrine.