Patent ID: 7585997

Claim:
A compound of Formula I or a tautomer thereof, or a ester thereof; wherein X 1 is selected from the group consisting of —O— and —NH—; wherein X 2 is one or more substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, —NO 2 , —ONO 2 , —CN; an optionally substituted aliphatic, alicyclic, heteroalip hatic, aromatic, heterocyclic, heteroaromatic moiety; —OR R , —S(=O) n R d , —NR b R c , —C(=O)R a , and —C(=O)OR a , wherein n is 0-2, R R is an optionally substituted aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, heteroaromatic or acyl moiety; R a , for each occurrence, is independently hydrogen or an optionally substituted aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, or a heteroaromatic moiety; R b and R c , for each occurrence, are independently selected from the group consisting of hydrogen; hydroxy; SO 2 R d ; aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, heteroaromatic or an acyl moiety; R d , for each occurrence, is independently selected from the group consisting of hydrogen; —N(R e ) 2 ; aliphatic, aryl and heteroaryl; and R e , for each occurrence, is independently hydrogen or aliphatic; wherein A is wherein R 2 is at least one halogen, X 2 is as defined above and R 3 and R 4 are independently hydrogen or an aliphatic group, wherein D is hydroxyl; nitrate; halide; tosylate; phosphate; —OSO 2 NR x R y , where R x and R y are independently hydrogen, or an aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, heteroaromatic or acyl moiety; —O—C 6 H 4 OC(═O)CH 3 ; an alkoxy moiety; an acyl moiety; or where R 7 is hydrogen or one or more nitro groups; with the proviso that the compound does not have the following structure and that when X 1 is O and X 2 is H, D is not nitrate.