Patent ID: 8692021

Claim:
A method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane or a pharmaceutically acceptable salt thereof, comprising the following steps: (iii) reacting 1-hydroxy-1,3,3,5,5-pentamethylcyclohexane with hydrogen cyanide in the presence of said acid, or with a compound that forms hydrogen cyanide in the presence of said acid, to yield a mixture comprising said acid, 1-formamido-1,3,3,5,5-pentamethylcyclohexane and hydrogen cyanide; (iv) hydrolyzing the mixture comprising an acid, 1-formamido-1,3,3,5,5-pentamethylcyclohexane and hydrogen cyanide obtained in step (iii) to yield 1-amino-1,3,3,5,5-pentamethylcyclohexane; and, optionally, (v) converting the 1-amino-1,3,3,5,5-pentamethylcyclohexane from step (iv) to a pharmaceutically acceptable salt thereof.