Patent ID: 7879875

Claim:
A compound represented by chemical formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof, wherein: X and Y are each independently selected from —CR 4 — and —N—; R 1 is selected from: (1) hydrogen, (2) halogen, (3) OH, and (4) alkoxy; R 2 is selected from: (1) NR a , (2) aryl, (3) heteroaryl, (4) heterocycloalkyl, and (5) OR a ; said heteroaryl, aryl and heterocycloalkyl are each optionally substituted with one or more substituents selected from R 6 , R 7 and R 8 ; R 3 is selected from: (1) aryl, (2) benzyl, (3) heteroaryl, and (4) heterocycloalkyl; said heteroaryl, aryl and heterocycloalkyl are each optionally substituted with one or more substituents selected from R 6 , R 7 and R 8 ; R 4 is selected from: (1) hydrogen, (2) C 1 -C 6 alkyl, (3) alkoxy, (4) CHO, (5) CONH 2 , (6) C(O) 2 R a , (7) C 0 -C 4 alkyl-OH, (8) O—C 1 -C 4 alkyl, (9) halogen, (10) aryl, (11) heteroaryl, (12) heterocycloalkyl, (13) COR a , (14) O—C—C4alkyl-N—C(O)—C 0 -C 2 alkyl(R b R c )—NH 2 , (15) heterocycloalkyl-C(O)—C 0 -C 2 alkyl(R b R c )—NH 2 , (16) N(R a )(R a ), (17) O—R a (18) N—C(O)—N-heterocycloalkyl, (19) O—C(O)—N-heterocycloalkyl, (20) N—C 1 -C 4 alkyl-N—R a , and (21) N—C 1 -C 4 alkyl-O—R a ; said heteroaryl and aryl are each optionally substituted with one or more substituents selected from R 6 , R 7 and R 8 ; R 6 , R 7 and R 8 are each independently selected from: (1) halogen, (2) C 1 -C 6 alkyl, (3) CN, (4) OR a , (5) alkoxy, (6) cycloalkyl, (7) C═R a (R a ), (8) CON(R a )(R a ), (9) aryl, (10) N(R a )(R a ), (11) heteroaryl, (12) hydrogen, (13) C 1 -C 4 —OH, (14) heterocycloalkyl, (15) CON-alkyl-CO 2 —R a , (16) CON-alkyl-CON(R a )(R a ), (17) CON-alkyl-N(R a )(R a ), (18) C(═O)R a , and (19) C(O) 2 R a ; said heteroaryl and aryl are each optionally substituted with one or more substituents selected from R a ; R a is selected from: (1) hydrogen, (2) halogen, (3) NH—C 1 -C 4 alkyl, (4) C 1 -C 6 alkyl, (5) C 1 -C 4 -alkyl-heteroaryl, (6) C 1 -C 4 -alkyl-cycloalkyl, (7) heteroaryl, (8) C 1 -C 4 alkyl-heterocycloalkyl, (9) heterocycloalkyl, (10) C 0 -C 4 alkyl-NH 2 , and (11) C 0 -C 4 alkyl-OH; R b and R c are each independently selected from hydrogen and alkyl, or R b and R c can join together to form a cycloalkyl.