Patent ID: 8273762

Claim:
A compound of formula (I): wherein n is 0 or 1; m is 0; R 2 and R 3 may be taken together with the nitrogen to which they are attached to form a 4-8 membered heterocyclic ring, said heterocyclic ring having 0 or 1 additional heteroatom members separated from the nitrogen of attachment by at least one carbon member and selected from >O, >S(O) 0-2 , and >NH, having 0 or 1 double bonds, having 0, 1, or 2 carbon members separated from the nitrogen of attachment by at least one carbon member which is a carbonyl, optionally benzo or pyrido fused, optionally having one carbon member that forms a bridge, and having 0-1 substituents R ff , R ff is selected from the group consisting of —C 1-6 alkyl halo, and —C 1-6 alkylOH; R 5 is selected from the group consisting of —H, —C 1-6 alkyl, —OH, —OC 1-6 alkyl, —SC 1-6 alkyl, and halo; Ar 1 is a heteroaryl ring selected from the group consisting of: d) a monocyclic aromatic hydrocarbon group having five ring atoms, having a carbon atom which is the point of attachment, having one carbon atom replaced by >O, >S, >NH, or >N(C 1-4 alkyl), having up to one additional carbon atom optionally replaced by —N═, optionally mono- or di-substituted with R t R t is a substituent independently selected from the group consisting of: —OH, —C 1-6 alkyl, —OC 1-6 alkyl, phenyl, —CN, —NO 2 , —N(R u )R v (wherein R u and R v are independently —H or —C 1-6 alkyl), —C(O)N(R u )R v , —N(R u )C(O)R v , —N(R u )SO 2 C 1-6 alkyl, —C(O)C 1-6 alkyl, —S(O) 0-2 -C 1-6 alkyl, —SO 2 N(R u )R v , —SCF 3 , halo, —CF 3 , —OCF 3 , —OCHF 2 , —COOH, and —COOC 1-6 alkyl; e) a monocyclic aromatic hydrocarbon group having six ring atoms, having a carbon atom which is the point of attachment, having one or two carbon atoms replaced by —N═, optionally mono- or di-substituted with R t ; and enantiomers, diastereomers thereof, and pharmaceutically acceptable salts, esters and amides thereof.