Patent ID: 8485985

Claim:
A method of determining Fractional Flow Reserve (FFR) in a patient, the method comprising: measuring, with a hemodynamic transducer or a sensor coupled to an intravascular sensor delivery device, a first blood pressure upstream of a location of interest in the patient during a phase of a cardiac cycle, measuring, with the sensor, a second blood pressure downstream of the location of interest in the patient in substantially the same phase of the cardiac cycle in which the first blood pressure was measured, and calculating, with a processor, FFR as a ratio of the first blood pressure to the second blood pressure, wherein the intravascular sensor delivery device comprises a distal sleeve and a proximal portion, the distal sleeve having a guidewire lumen for sliding over and receiving a separate medical guidewire and being insertable in a leading direction into a body of the patient, the proximal portion having a main section extending proximally from the distal sleeve and a distal transition extending distally from the main section, wherein the distal transition is fixedly coupled to an outer surface of the distal sleeve, the proximal portion comprises a communication channel for communicating a signal from the sensor to a location outside of the patient, and the proximal portion is adapted to facilitate positioning of the sensor within an anatomical structure of the patient.