Patent ID: 7635481

Claim:
A composition which comprises: an effective amount of an inactivated Ehrlichia canis , a pharmacologically acceptable carrier, and an immunogenically stimulating amount of an adjuvant system consisting of an antibody response inducing agent and a cell-mediated response inducing agent, wherein said antibody response inducing agent is selected from the group consisting of ethylene maleic anhydride, styrenated acrylic copolymer and a mixture thereof, and said cell-mediated response inducing agent is selected from the group consisting of an oil-in-water emulsion, an attenuated Mycobacterium bovis and a mixture thereof but not a Th1-related cytokine, wherein said inactivated Ehrlichia canis is selected from the group consisting of one or more E. canis strains designated as Ebony deposited under ATCC Accession Number PTA-5812, Broadfoot deposited under ATCC Accession Number PTA-5811 and a mixture thereof.