Patent ID: 7371857

Claim:
A method of preparing a compound according to Structure 3 comprising: reacting a heterocyclic base according to Structure 1 with a compound according to Structure 2 in dimethylacetamide to form a product according to Structure 3; wherein X, Y and Z are N; wherein R 1 is NH 2 ; wherein R 2 is H; wherein R 3 is H; wherein R 4 , R 5 , R 6 , and R 7 are independently H, halogen, OH, NH 2 , CO(NH 2 ), CNH(NH 2 ), N 3 , or substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, or alkaryl; wherein n is an integer between 1 and 3; and isolating Structure 3 from the dimethylacetamide solvent using isopropanol or tert-butylmethylether.