Patent ID: 7425649

Claim:
A compound of Formula (I): wherein X is selected from a covalent bond, S, and O; Y is S or O; Z is O or CH 2 , provided when Y is O, then Z is O; R 1 and R 2 are independently selected from H, C 1-3 alkyl, C 1-3 alkoxy, halo, and NR a R b wherein R a and R b are independently H or C 1-3 alkyl; R 3 and R 4 are independently selected from H, halo, cyano, C 1-5 alkyl, hydroxy, C 2-4 acyl, C 1-4 alkoxy, and NR c R d wherein R c and R d are independently H or C 1-3 alkyl, provided that R 3 and R 4 are not both H; R 5 and R 6 are independently selected from H, C 1-8 alkyl and substituted C 1-8 alkyl, provided that R 5 and R 6 are not both H; R 7 is selected from H, halo, C 1-8 alkyl, and phenyl; R 8 and R 9 are independently selected from halo, phenyl, C 1-9 alkyl, C 1-8 alkoxy, C 2-9 alkenyl, C 2-9 alkenyloxy, C 3-7 cycloalkyl, C 3-7 cycloalkoxy, C 3-7 cycloalkyl-C 1-7 alkyl, C 3-7 cycloalkyl-C 1-7 alkoxy, C 3-7 cycloalkyloxy-C 1-6 alkyl, and C 3-7 cycloalkyloxy-C 1-7 alkoxy, or R 8 and R 9 together form C 1-9 alkylidenyl or C 3-9 alkenylidenyl; or R 8 , R 9 and the carbon atom to which they are attached together form C 3-7 cycloalkyl or 5-or 6-membered heterocyclyl; n is 0, 1 or 2; and m is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.