Patent ID: 8158788

Claim:
A method for the nitration of 4,6-dihydroxy-2-methylpyrimidine comprising the steps of: (1) dissolving 4,6-dihydroxy-2-methylpyrimidine in concentrated sulfuric acid to form a solution of the 4,6-dihydroxy-2-methylpyrimidine; (2) adding halogenated organic solvent to the 4,6-dihydroxy-2-methylpyrimidine solution obtained from the above step (1) to form a mixed solution of the 4,6-dihydroxy-2-methylpyrimidine solution and the halogenated organic solvent; and (3) adding concentrated nitric acid to the mixed solution obtained from the above step (2) and stirring the solution to form a 4,6-dihydroxy-5,5-dinitro-2-(dinitromethylene)-2,5-dihydropyrimidine.