Patent ID: 8097610

Claim:
A compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein Ring Q is optionally substituted monocyclic aryl, optionally substituted monocyclic heteroaryl, optionally substituted fused aryl or optionally substituted fused heteroaryl, provided that Ring Q is not unsubstituted 11H-dibenz[b,e]-azepine-6-yl, Y 1 is a bond, —NR 6 — or —NR 6 —CO— wherein R 6 is hydrogen or optionally substituted lower alkyl, provided that Y 1 is —NR 6 —CO— when Ring Q is unsubstituted monocyclic aryl, and Ring Q is phenyl substituted with alkyl halide when Ring Q is monocyclic aryl and Y 1 is a bond, Ring A is a group of the formula: R 17 is optionally substituted lower alkyl, cyano, optionally substituted nonaromatic heterocycle, optionally substituted heteroaryl, optionally substituted amino, optionally substituted lower alkoxy, aryl lower alkyl or optionally substituted cycloalkyl, the bond from N binds with Y 1 and the bond from C binds with Y 2 , a group of the formula: —Y 2 Z 1 — is a group of the formula: provided that a group of the formula: —Y 2 Z 1 — is not —SO 2 — and, a group of the formula: —Y 2 Z 1 — is not —CH 2 —CH 2 —O— or —O— when Ring Q is unsubstituted benzothiazole-2-yl or unsubstituted benzoxazole-2-yl, R 7 are each independently hydrogen, optionally substituted lower alkyl or optionally substituted cycloalkyl, R 8 and R 9 are each independently hydrogen or optionally substituted lower alkyl, n is an integer between 0 and 3, Z 1 is a bond, —O—, —S— or —NR 9 — wherein R 9 is hydrogen, optionally substituted lower alkyl, optionally substituted acyl, optionally substituted lower alkylsulfonyl or optionally substituted arylsulfonyl, Ring B is optionally substituted aromatic carbocyclediyl or optionally substituted aromatic heterocyclediyl, Y 3 is a bond, optionally substituted lower alkylene optionally intervened by —O—, cycloalkylene optionally intervened by —O— or optionally substituted lower alkenylene, Z 2 is COOR 3 , C(═NR 3 )NR 14 OR 15 , CONHCN or a group of the formula: R 3 , R 14 and R 15 are each independently hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted aryl or optionally substituted heteroaryl, and provided that a compound wherein a group of the formula: —Y 2 Z 1 — is a group of the formula: n is 0 and Z 1 is a bond is excluded.