Patent ID: 7968590

Claim:
A compound represented by formula (3): or a pharmaceutically acceptable salt thereof where A 1 is H, lower alkyl, or optionally-substituted lower alkyl; R 1a and R 1b are separately H, lower alkyl, optionally-substituted lower alkyl, lower alkylene, optionally substituted lower alkylene; or A 1 together with either R 1a or R 1b form an optionally substituted heterocycloalkyl of 3 to 6 atoms; Y is H, an alkyl group, an alkynyl group, a cycloalkyl group of 3 to 7 carbon atoms, aryl, heteroaryl, arylalkyl, optionally-substituted versions of these groups, hydroxy substituted versions of these groups, or Y together with Z, M, G, or R 10 forms a carbocyclic ring, or a heterocyclic ring containing 1 to 5 heteroatoms, where Y is linked to Z, M, G, or R 10 ; Z is H, alkyl, hydroxy, amino, alkylamino, diakylamino, alkoxy, cycloalkyl, cycloalkyloxy, aryl, heteroaryl, aryloxy, or heteroaryloxy; or Z together with Y, M, G, or R 10 form a carbocyclic ring, or a heterocyclic ring containing 1 to 5 heteroatoms, where Z is linked to Y, M, G, or R 10 ; M is an optionally-substituted alkyl, alkenyl, or alkynyl; an optionally-substituted alkyl, alkenyl, or alkynyl of 1 to 5 carbon atoms; an optionally-substituted alkylene, alkenylene, or alkynylene; or an optionally-substituted alkylene, alkenylene, or alkynylene of 1 to 5 carbon atoms; G is a bond, a heteroatom, —(C═O)—; —S(O) t — where t=0,1, or 2; —NR 18 —; —NCOR 18 —; or —NS(O) x R 18 — where x=0, 1, or 2, and R 18 is lower alkyl, optionally-substituted lower alkyl, or cycloalkyl or R 18 is contained within a carbocyclic, or heterocyclic ring containing 1 to 5 heteroatoms, where R 18 is linked to Z, M, or R 10 ; and R 10 is any one of structures (4a), or (4b): where independently R 11 , R′ 11 , or any of R 14-17 is H, halogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, hydroxyl, alkoxy, polyalkylether, amino, alkylamino, dialkylamino, alkyloxyalkyl, sulfonate, aryloxy or heteroaryloxy; independently R 11 , R′ 11 , or any of R 14-17 is H, optionally-substituted alkyl, alkenyl, alkynyl, aryl, heteroaryl, hydroxyl, alkoxy, polyalkylether, amino, alkylamino, dialkylamino, alkyloxyalkyl, aryloxy, or heteroaryloxy; or independently R 11 , R′ 11 , or any of R 14-17 is acyl or acetyl groups, carboxylate, sulfonate, sulfone, imine, or oxime groups; or groups R 11 , R′ 11 , or any of R 14-17 is contained within a carbocyclic ring, or a heterocyclic ring containing 1 to 5 heteroatoms, and linked to groups at position Y, Z, M, G, R 11 , R′ 11 , or any of R 14-17 .