Patent ID: 8067582

Claim:
A compound of Formula (I): or a pharmaceutically-acceptable salt or stereoisomer thereof, wherein: L is a bond, CR 8 R 9 , or CR 8 R 9 CR 10 R 11 ; R 1 is H, C 1-4 alkyl optionally substituted with OH, —CH 2 OCH 2 (phenyl), —C(═O)OR a wherein R a is H or C 1-4 alkyl, or —C(═O)NR b R c wherein R b and R c are independently H and/or C 1-4 alkyl; R 2 is i) H, ii) C 1-4 alkyl optionally substituted with OH, iii)-C(═O)OR a wherein R a is H or C 1-4 alkyl optionally substituted with aryl, or iv)-C(═O)NHR c wherein R c is phenyl or C 1-2 alkyl optionally substituted with aryl or —CF 3 ; R 3 is 1- or 2-ring aryl or heteroaryl which is optionally substituted with 1-3 substituents independently selected from methyl, cyclopropyl, —CF 3 , halogen, —C≡CH, —CN, —NH 2 , —NO 2 , and/or —OR a wherein each R a is independently C 1-3 alkyl optionally substituted with 1 or more halogens; R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , and R 11 are independently H and/or C 1-4 alkyl; and Q 1 , Q 2 , Q 3 , and Q 4 are each independently: i) H, ii) OH, iii) —N 3 , iv) CN, v) C 1-4 alkyl optionally substituted with OH, —C(═O)NHCH 3 , or —C(═O)N(CH 3 ) 2 vi) monocyclic heterocycle, vii) —NHOR a wherein R a is C 1-4 alkyl, viii) —C(═O)R b wherein R b is H or C 1-4 alkyl; ix) —C(═O)OR a wherein R a is H or C 1-4 alkyl, x) —C(═O)NR b R c wherein R b and R c are independently H or C 1-4 alkyl, xi) —NHC(═O)OR a wherein R a is C 1-4 alkyl optionally substituted with OH, OCH 3 , or monocyclic heterocycle, xii) —NHC(═O)R a wherein R a is C 1-4 alkyl optionally substituted with —OCH 3 , —N(CH 3 ) 2 , or monocyclic heterocycle, xiii) —NR b R c wherein R b and R c are independently H or monocyclic heterocycle optionally substituted with halogen or —CF 3 , xiv) —NHSO 2 R a wherein R a is monocyclic heterocycle, C 1-4 alkyl optionally substituted with —CF 3 , C 3-6 cycloalkyl, or phenyl, or phenyl optionally substituted with halogen or —NHC(═O)(C 1-4 alkyl), xv) —NHSO 2 NR b R c wherein R b and R c are independently H and/or C 1-4 alkyl, or xvi) —SO 2 R a wherein R a is C 1-4 alkyl or phenyl optionally substituted with halogen; or Q 1 and Q 2 together or Q 3 and Q 4 together are: i) ═CHR d wherein R d is H, —C(═O)OR a or —C(═O)NR b R c wherein R a , R b , and R c are independently H and/or C 1-4 alkyl, ii) ═O, iii) ═NOR b wherein R b is H, phenyl, monocyclic heterocycle, or C 1-4 alkyl optionally substituted with phenyl, iv) ═NR d wherein R d is monocyclic heterocycle, v) ═NNR c R d wherein R c and R d are independently H or C 1-4 alkyl; or Q 1 and Q 3 together are ═O wherein Q 2 and Q 4 are each H.