Patent ID: 8084601

Claim:
An oligomer for ameliorating DMD, the oligomer comprising at least 25 contiguous bases of a base sequence selected from the group consisting of: a) (SEQ ID NO: 10) CXG XXG CCX CCG GXX CXG AAG GXG XXC XXG; (SEQ ID NO: 11) b) CAA CXG XXG CCX CCG GXX CXG AAG GXG XXC; and (SEQ ID NO: 12) c) XXG CCX CCG GXX CXG AAG GXG XXC XXG XAC, wherein X=U or T, wherein the oligomer's base sequence can vary from the above sequence at up to two base positions, and wherein the molecule can bind to a target site to cause exon skipping in an exon of the dystrophin gene.