Patent ID: 8197802

Claim:
A method for augmenting soft or hard tissue within a mammalian body, comprising: (a) providing a first crosslinkable component having m nucleophilic groups, wherein m≧2 and the m nucleophilic groups are primary amino groups; (b) providing a second crosslinkable component having n electrophilic groups capable of reaction with the m nucleophilic groups to form covalent bonds, wherein n≧2 and m+n≧5; (c) applying the first and second crosslinkable components to the tissue; and (d) allowing the first and second crosslinkable components to crosslink in situ, wherein the first and second crosslinkable components are biocompatible, synthetic, and nonimmunogenic; and wherein the first crosslinkable component is C 2 -C 6 hydrocarbyl substituted with amino groups, or wherein the first crosslinkable component is a secondary or tertiary amine NR 1 R 2 R 3 , wherein R 1 is hydrogen or an amino-substituted lower alkyl group, and R 2 and R 3 are amino-substituted lower alkyl groups.