Patent ID: 7589108

Claim:
A compound of formula I wherein W is N; R is halogen, CN, OCO 2 R 9 , CO 2 R 10 , CONR 11 R 12 , SO x R 13 , NR 14 R 15 , OR 16 , COR 17 or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 7 cycloalkyl, aryl or heteroaryl group each optionally substituted; R 1 is an optionally substituted C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, aryl, or heteroaryl group or an optionally substituted 8- to 13-membered bicyclic or tricyclic ring system having a N atom at the bridgehead and optionally containing 1,2 or 3 additional heteroatoms selected from N, O or S; R 3 and R 4 are each independently H or an optionally substituted C 1 -C 6 alkyl group; R 5 is H or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 7 cycloalkyl, cycloheteroalkyl, aryl or heteroaryl group each optionally substituted; R 6 is a C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 2 -C 6 alkenyl or C 2 -C 6 alkynyl group each optionally substituted; R 7 and R 8 are each independently H or a C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 2 -C 6 alkenyl or C 2 -C 6 alkynyl group each optionally substituted; m, n and p are each independently 0 or an integer of 1, 2 or 3; q and x are each independently 0 or an integer of 1 or 2; R 9 , R 10 , R 13 and R 17 are each independently H or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, cycloheteroalkyl, aryl or heteroaryl group each optionally substituted; R 11 and R 12 are each independently H or an optionally C 1 -C 6 alkyl group or R 11 and R 12 may be taken together with the atom to which they are attached to form a 5- to 7-member ring optionally containing another heteroatom selected from O, N or S; R 14 and R 15 are each independently H or an optionally substituted C 1 -C 4 alkyl group or R 14 and R 15 may be taken together with the atom to which they are attached to form a 5- to 7-membered ring optionally containing another heteroatom selected from O, NR 18 or SO x ; R 16 is a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 7 cycloalkyl, cycloheteroalkyl, aryl or heteroaryl group each optionally substituted; and R 18 is H or a C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 7 cycloalkyl, cycloheteroalkyl, aryl or heteroaryl group each optionally substituted; or the stereoisomers thereof or the pharmaceutically acceptable salts thereof.