Patent ID: 6852726

Claim:
A compound of the Formula I: wherein: X is —S(O) n — or —C(O); A is C 1-6 alkyl, aryl, heteroaryl, hydroxyalkyl, or —(CH 2 ) p —NR a R b ; R 1 , R 2 , R 3 , and R 4 each independently is hydrogen, halogen, haloalkyl, C 1-6 alkyl, hydroxy, C 1-6 alkoxy, C 1-6 alkylthio, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyl, C 1-6 alkylsulfonylamino, C 1-6 alkylaminosulfonyl, cyano, nitro, —NR a R b , phenyl, benzyl or benzyloxy, wherein said phenyl, benzyl and benzyloxy are optionally substituted with C 1-6 alkyl, halogen, cyano, nitro, haloalkyl, or C 1-6 alkoxy; R 5 is hydrogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkoxyalkyl, C 1-6 alkylthio, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyl, hydroxyalkyl, hydroxyalkylamino, halogen, haloalkyl, cyano, —NR a R b , —NR c —C 1-6 alkyl-NR a R b , or R 5 and A together form a C 2 -C 3 alkylene radical; R 6 is hydrogen or C 1-6 alkyl; R′ and R″ each independently is hydrogen or alkyl; R a , R b , and R c each independently is hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, aminoalkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, alkylthioalkyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, or arylsulfonyl, or R a and R b together with the nitrogen they are attached to may also form a 5- to 7-membered non-aromatic heterocyclic ring optionally incorporating an additional ring heteroatom chosen from N, O, or S; m is 1 or 2; n is 0, 1 or 2 with the proviso that when n is 0, R 5 is not —NR a R b ; and p is 0, 1 or 2; or pharmaceutically acceptable salts thereof.