Patent ID: 7276637

Claim:
A method of preparing a cyclohexanone of formula (1): comprising: (a) cycloaddition of a 2-trialkylsilyloxybutadiene of formula (2a) to a vinyl derivative of formula (2b): to form a silyl enol ether of formula (3): and (b) hydrolysis of said silyl enol ether to form the cyclohexanone of formula (1); wherein, in formulae (1), (2a), (2b) and (3), R represents C 1-6 alkyl; Ar 1 represents C 6-10 aryl or heteroaryl, either of which bears 0-3 substituents independently selected from halogen, CN, NO 2 , CF 3 , OH, OCF 3 , C 1-4 alkoxy or C 1-4 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy; and Ar 2 represents C 6-10 aryl or heteroaryl, either of which bears 0-3 substituents independently selected from halogen, CN, NO 2 , CF 3 , OH, OCF 3 , C 1-4 alkoxy or C 1-4 alkyl which optionally bears a substituent selected from halogen, CN, NO 2 , CF 3 , OH and C 1-4 alkoxy.