Patent ID: 8232410

Claim:
A molecule of formula I wherein: R 1 represents NH 2 , NHR 6 , NR 9 R 10 , NR 6 CONR 9 R 10 , NR 6 CSNR 9 R 10 , OH, OR 6 , SH, SR 6 , CHO, COOR 6 , COR 6 , CH 2 OH, CR 7 R 8 OH, CH 2 OR 6 , CR 7 R 8 OR 6 , CH 2 NH 2 , CR 7 R 8 NH 2 , CR 7 R 8 NR 9 R 10 , alkyl, cycloalkyl, aryl, or halo; R 2 and R 4 independently represent H, alkyl, cycloalkyl, or aryl; R 3 represents alkyl, cycloalkyl, or aryl; R 5 represents H, R 6 , OR 6 , SR 6 , NH 2 , NHR 6 , or NR 9 R 10 ; X represents O, S, NH, or NR 6 ; R 6 , R 7 , R 8 , R 9 , and R 10 independently represent alkyl, cycloalkyl, aryl, or halo; or R 2 and R 3 ; R 4 and R 5 ; and R 9 and R 10 independently, may be combined to represent a heterocyclic alkyl or heterocyclic aryl; or R 7 and R 8 may be combined to represent a cycloalkyl; alkyl groups are branched or unbranched, saturated or unsaturated, and have 1-18 carbon atoms in their longest chain; cycloalkyl groups are carbocyclic or heterocyclic, fused or unfused, non-aromatic ring systems having a total of 5-16 ring members including substituent rings; aryl groups are carbocyclic or heterocyclic; carbocyclic aryl groups are fused or unfused ring systems having a total of 6-16 ring members including substituent rings; heterocyclic aryl groups are fused or unfused ring systems having a total of 5-16 ring members including substituent rings; halo substituents are fluoro, chloro, or bromo; each alkyl, cycloalkyl, and aryl, independently, may be unsubstituted or substituted with one or more substituent at any position; alkyl substituents are halo, hydroxyl, OR 6 , SR 6 , NH 2 , NHR 6 , NR 9 R 10 , cycloalkyl, or aryl; cycloalkyl substituents are halo, hydroxyl, OR 6 , SR 6 , NH 2 , NHR 6 , NR 9 R 10 , alkyl, cycloalkyl, or aryl; aryl substituents are halo, hydroxyl, OR 6 , SR 6 , NH 2 , NHR 6 , NR 9 R 10 , alkyl, cycloalkyl, aryl, nitro, or carboxyl; and heterocyclic alkyl and heterocyclic aryl have at least one heteroatom selected from oxygen, nitrogen and sulfur; or a pharmaceutically acceptable salt thereof.