Patent ID: 7456186

Claim:
A compound of formula I wherein X is N, NO or CR 19 ; Y is N, NO or CR 11 ; Z is N, NO or CR 20 with the proviso that no more than two of X, Y or Z may be N or NO; R 1 and R 2 are each independently H, CN or an optionally substituted C 1 -C 4 alkyl group; R 3 and R 4 are each independently H, or an optionally substituted C 1 -C 4 alkyl group or R 3 and R 4 may be taken together to form a 3- to 7-membered ring optionally containing one or two heteroatoms selected from O, N or S or R 3 may be taken together with the atom to which it is attached and an adjacent carbon atom to form a double bond; R 5 and R 6 are each independently H, halogen, NO 2 , CN, OR 13 , NR 14 R 15 or a C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl or C 3 -C 8 cycloalkyl group each optionally substituted or when attached to adjacent carbon atoms R 5 and R 6 may be taken together with the atoms to which they are attached to form an optionally substituted 5- to 7-membered ring optionally containing one or two heteroatoms selected from O, N or S; R 7 , R 8 , R 9 , R 10 , R 11 , R 19 and R 20 are each independently H, halogen, NO 2 , CN, OR 16 , NR 17 R 18 or a C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl or C 3 -C 8 cycloalkyl group each optionally substituted; m is 0 or 1; n is 1; ------ is a single bond or a double bond with the proviso that when m is 0 then ------ must be a single bond; R 13 and R 16 are each independently H or a C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 8 cycloalkyl or aryl group each optionally substituted; and R 14 , R 15 , R 17 and R 18 are each independently H or C 1 -C 4 alkyl; or a tautomer thereof, a stereoisomer thereof or a pharmaceutically acceptable salt thereof.