Patent ID: 8617143

Claim:
A device for controlled release of one or more active ingredients, the device comprising: a) at least two release apertures, each release aperture operably associated with a deflectable member comprising a rupturable membrane and/or a deflectable cap; b) a base comprising a porous membrane layer, and a non-porous substrate layer in contact with the porous membrane layer; and c) at least two chambers, each chamber juxtaposed between a respective one of the release apertures and the porous membrane layer, each chamber containing a matrix comprising one or more active ingredients and an agent that expands when contacted with an aqueous solution, wherein the non-porous substrate layer comprises a plurality of channels configured with at least two pre-determined patterns, each pre-determined pattern adapted for fluid communication with a respective one of the chambers, and wherein each channel of the plurality of channels is suitable for contacting the porous membrane layer with an aqueous solution, wherein the device is suitable for implantation in a biological system.