Patent ID: 8679500

Claim:
A method of treating CD5+ HLA-DR+ B or T cell related diseases in a subject in need thereof, comprising the step of administering to said subject at least one CD5 antibody and at least one HLA-DR antibody, wherein said at least one CD5 antibody comprises: (i) a variable light chain comprising the CDR1 (L1) of sequence SEQ ID NO: 3, the CDR2 L2 of sequence CDR3 L3 of sequence SEQ ID NO: 5 and, (ii) a variable heavy chain comprising the CDR1 (H1) of sequence SEQ ID NO: 6, the CDR2 (H2) of sequence SEQ ID NO: 7, and the CDR3 (H3) of sequence SEQ ID NO: 8, and wherein said at least one HLA-DR antibody comprises: (i) a variable light chain comprising the CDR1 (L1) of sequence SEQ ID NO: 11, a CDR2 (L2) of sequence SEQ ID NO: 12, and a CDR3 (L3) of sequence SEQ ID NO: 13 and, (ii) a variable heavy chain comprising the CDR1 (H1) of sequence SEQ ID NO: 14, a CDR2 (H2) of sequence SEQ ID NO: 15, and a CDR3 (H3) of sequence SEQ ID NO: 16.