Patent ID: 8754240

Claim:
A process for the manufacture of a compound of Formula II the process comprising the steps of: (a) in the presence of a solvent, reacting a compound of Formula III: wherein R 1 and R 2 are independently selected from the group consisting of chlorine, bromine, fluorine, iodine, triflyl and tosyl; with an ester of Formula IV wherein R 3 is C 1-6 alkyl or benzyl; to form a compound of Formula V: (b) in the presence of an arylalkyl ammonium salt or a tetraalkyl ammonium salt, reacting a compound of Formula V with hydroxide ion to form a compound of Formula VI (c) in the presence of an acid, decarboxylating a compound of Formula VI to form a compound of Formula VII; and (d) reducing the compound of Formula VII to form the compound of Formula II.