Patent ID: 8735378

Claim:
A method of treating inflammation that is associated with a metabolic disorder selected from the group consisting of Type II diabetes, insulin resistance, atherosclerosis, dyslipidemia, retinopathy associated with diabetic complications, nephropathy associated with diabetic complications, neuropathy associated with diabetic complications, and macular edema associated with diabetic complications, comprising administering to a patient in need thereof an effective amount of a compound of Formula III: or a pharmaceutically acceptable salt, enantiomer, or stereoisomer thereof, wherein W 1 is null and W 2 is independently null, O, or NH; represents an optional bond that when present requires that Q is null; each a and c are independently H, CH 3 , —OCH 3 , —OCH 2 CH 3 , or C(O)OH; each b is H, CH 3 , C(O)OH, or O—Z; each d is H or C(O)OH; each n, o, p, and q is independently 0 or 1; each Z is H or with the proviso that there is at least one in the compound; each r is independently 2, 3, or 7; each s is independently 3, 5, or 6; each t is independently 0 or 1; u is 0 or 1; with the proviso that when r is 7, s is 3; Q is null, C(O)CH 3 , Z, e is H or any one of the side chains of the naturally occurring amino acids; W 3 is null, —O—, or —N(R)—; R is H or C 1 -C 3 alkyl; and T is H, C(O)CH 3 , or Z.