Patent ID: 8053417

Claim:
An alpha-Hexosylceramide (alpha-HexCer) conjugate according to formula (I) wherein A is CH 2 or CO; B represents R 4 , OR 4 , NHR 4 , PO 3 R 4 , or SO 3 R 4 where R 4 is a conjugate moiety which is a water-soluble and physiologically tolerated polymer; R 1 and R 2 can be identical or different and are independently a linear or branched C 10 -C 30 alkyl- and/or alkenyl-groups; D represents CH 2 or CH(OH); R 3 represents hydrogen or OH; R 5 and R 6 are substituents where either R 5 represents hydrogen and R 6 represents hydrogen, OH, OC 1 -C 6 alkyl, NH2, NHCOC 1 -C 6 alkyl or R 6 is hydrogen and R 5 represents hydrogen, OH, OC 1 -C 6 alkyl, NH 2 , NHCOC 1 -C 6 alkyl; R 7 and R 8 are substituents where either R 7 represents hydrogen and R 8 represents hydrogen, OH, OC 1 -C 6 alkyl, NH 2 , NHCOC 1 -C 6 alkyl or R 8 is hydrogen and R 7 represents hydrogen, OH, OC 1 -C 6 alkyl, NH 2 , NHCOC 1 -C 6 alkyl; R 9 and R 10 are substituents where either R 9 represents hydrogen and R 10 represents hydrogen, OH, OC 1 -C 6 alkyl, NH 2 , NHCOC 1 -C 6 alkyl or R 10 is hydrogen and R 9 represents hydrogen, OH, OC 1 -C 6 alkyl, NH 2 , NHCOC 1 -C 6 alkyl; or salts or solvates thereof.