Patent ID: 7413871

Claim:
A method for determining if a pancreas isolated from a member of a species will be a source of therapeutically useful islets, comprising: (i) determining warm ischemia time of said isolated pancreas, and at least two of: (ii) determining color of said isolated pancreas, (iii) determining fat content of said isolated pancreas, (iv) determining demarcation of islets in said pancreas, and (v) determining average size of islets isolated from said isolated pancreas, wherein: (a) in (i) a warm ischemia time of 20 minutes or less is assigned a score of +1, and one greater than 20 minutes is assigned a score of −1; (b) in (ii), determining color comprises determining a reflectance ratio and if said reflectance ratio is 60 or more, assigning a score of +1, and if said ratio is less than 60 assigning a score of −1; (c) a fat content below 25% is assigned a score of +1, and 25% or above is scored at −1; (d) in (iv), determining demarcation comprises assessing demarcation of islets and assigning a score of +1, if more than 50% of islets are well demarcated and assigning a score of −1 if 50% or less of islets are well demarcated, and (e) an average diameter for islets equal to or greater than the average value for said species is assigned a score of +1, and an average diameter for islets below the average value for said species is assigned a score of −1, and (f) comprising adding the scores obtained in (a) through (e), whereby a final positive score indicates said pancreas is a source of therapeutically useful islets.