Patent ID: 8900297

Claim:
A polymeric ophthalmic or otorhinolaryngological device material formed by polymerizing a composition comprising a) 70 to 98% (w/w) of a monofunctional acrylate or methacrylate monomer of formula [1]: wherein B=—O(CH 2 ) n —, —(OCH 2 CH 2 ) n —, —NH(CH 2 ) n —, or —NCH 3 (CH 2 ) n —; R 1 ═H, CH 3 , CH 2 CH 3 , or CH 2 OH; n=0-12; A=C 6 H 5 or O(CH 2 ) m C 6 H 5 , where the C 6 H 5 group is optionally substituted with —(CH 2 ) n H, —O(CH 2 ) n H, —CH(CH 3 ) 2 , —C 6 H 5 , —OC 6 H 5 , —CH 2 C 6 H 5 , F, Cl, Br, or I; and m=0-18; b) a difunctional acrylate or methacrylate cross-linking monomer of formula [2]: wherein R 2 , R 3 independently=H, CH 3 , CH 2 CH 3 , or CH 2 OH; W, W′ independently=O(CH 2 ) d , NH(CH 2 ) d , NCH 3 (CH 2 ) d , O(CH 2 ) d C 6 H 4 , O(CH 2 CH 2 O) d CH 2 , O(CH 2 CH 2 CH 2 O) d CH 2 , O(CH 2 CH 2 CH 2 CH 2 O) d CH 2 , or nothing; J=(CH 2 ) a , O(CH 2 CH 2 O) b , O, or nothing, provided that if W and W′=nothing, then J≠nothing; d=0-12; a=1-12; and b=1-24; and c) 2 to 4% (w/w) of a hydrophilic side-chain macromer of formula [3c]: wherein for formula [3c]: e=1-50; X=—O—, NH—, —N(CH 3 )—, —N(CH 2 CH 3 )—, or —N(C 6 H 5 )—; Y=—H, —(CH 2 ) p OH, —CH 2 CH 2 N(CH 3 ) 2 , —CH 2 CH 2 N(CH 2 CH 3 ) 2 , —CH 2 CH(OH)CH 2 OH, —(CH 2 CH 2 O) p CH 3 , —(CH 2 CH 2 O) p H, —(CH 2 CH 2 O) p C 6 H 5 , or p=1-12; q=1-230; T, T′ independently=O(CH 2 ) d′ , NH(CH 2 ) d′ , NCH 3 (CH 2 ) d′ , O(CH 2 ) d′ C 6 H 4 , O(CH 2 CH 2 O) d′ CH 2 , O(CH 2 CH 2 CH 2 O) d′ CH 2 , O(CH 2 CH 2 CH 2 CH 2 O) d′ CH 2 , or nothing; K═(CH 2 ) a′ , O(CH 2 CH 2 O) b′ , O, or nothing, provided that if T and T′=nothing, then K≠nothing; d′=0-12; a′=1-12; b′=1-24; L=H, CI, Br, —CH 2 C(O)CH 3 , CH 2 C(O)C(CH 3 ) 3 , —CH 2 C(O)C 6 H 5 , —CH 2 C(O)C 6 H 4 OH, —CH 2 C(O)C 6 H 4 OCH 3 , or —CH 2 CH═CH 2 ; R 4 , R 5 independently=H, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , CH(CH 3 ) 2 , CH 2 CH 2 CH 2 CH 3 , or CH 2 CH(CH 3 ) 2 ; and R 7 ═H, CH 3 , CH 2 CH 3 , or CH 2 OH.