Patent ID: 8466128

Claim:
A composition suitable for topical administration to a mammalian subject, the composition comprising, by mass, from about 0.05% to about 5% of a sodium hyaluronate blend of at least three types of sodium hyaluronate with distinct molecular weight ranges and a pharmaceutically acceptable excipient, wherein from about 0.1 wt % to about 5 wt % of the sodium hyaluronate blend in the composition has a molecular weight ranging between about 0.01 megadaltons and about 0.4 megadaltons, wherein from about 0.1 wt % to about 5 wt % of the sodium hyaluronate blend in the composition has a molecular weight ranging between about 0.5 megadaltons and about 1.6 megadaltons, and wherein from about 50 wt % to about 95 wt % of the sodium hyaluronate blend in the composition has a molecular weight ranging between about 1.7 megadaltons and about 4.0 megadaltons; and wherein the pharmaceutically acceptable excipient is predominantly in the liquid phase at ambient temperature.