Patent ID: 8309584

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 is halogen, C 1-3 alkyl, C 1-3 alkoxy or trifluoromethyl; R 2 is halogen, C 1-3 alkyl, C 1-3 alkoxy or trifluoromethyl; R 3 is hydrogen or halogen; R 4 is hydrogen, NR 5 R 6 , carbocycle, substituted carbocycle, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, C 1-8 alkyl optionally substituted by alkoxy or halogen, C 2-6 alkenyl optionally substituted by alkoxy or halogen, (CH 2 ) m —C 3-6 carbocycle optionally substituted by alkoxy or halogen, or (CH 2 ) m —R 7 , m being 1 or 2; R 5 and R 6 are each independently hydrogen, C 1-6 alkyl, substituted C 1-6 alkyl, C 2-6 alkenyl, substituted C 2-6 alkenyl, C 3-7 cycloalkyl, substituted C 3-7 cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl; or R 5 and R 6 , together with the nitrogen atom to which they are bonded, form a 4- to 10-membered saturated or unsaturated heterocyclic ring which is optionally substituted by one or more C 1-3 alkyl, benzyl, phenyl, C 1-3 alkoxy or halogen; R 7 is phenyl, furanyl, benzofuranyl, thienyl, benzothienyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridizinyl, tetrahydrofuranyl, tetrahydropyranyl, dioxanyl, 1,4-benzodioxanyl or benzo[1,3]dioxolyl, each being optionally substituted by one or more groups consisting of halogen, C 1-3 alkyl and C 1-2 alkoxy, each optionally having one to three fluorine substitutes; X is a sulfur atom, a sulfoxide (S═O) or a sulfone (SO 2 ) moiety; Y is methyl or ethyl; and Z is O or S.