Patent ID: 7348353

Claim:
A compound of formula I wherein n is 0 or 1 and A is hydroxy X is hydrogen and Y is hydrogen, or A forms a single bond with X or with Y; R 0 is hydrogen, (C 1-4 )alkyl, (C 1-4 )alkoxy, trifluoromethyl, halogen, cyano, nitro, —COOR 1 wherein R 1 is (C 1-4 )alkyl or —COR 2 wherein R 2 is hydrogen or (C 1-4 )alkyl, and R is —COR 3 , —COOR 3 , —CONR 4 R 5 or —SO 2 R 6 , wherein R 3 is (C 1-4 )alkyl, (C 3-7 )cycloalkyl or optionally substituted phenyl, 2-pyridyl or 2-thienyl, R 4 and R 5 , independently, are hydrogen or (C 1-4 )alkyl and R 6 is (C 1-4 )alkyl, (C 3-7 )cycloalkyl or optionally substituted phenyl, R′ is hydrogen or (C 1-4 )alkyl and R″ is hydrogen, or (C 1-4 )alkyl, or R′ and R″ together form a group —CH 2 —(CH 2 ) m —wherein m is 0, 1 or 2, in which case one of n and m is different from 0, with the proviso that R 0 is different from hydrogen, trifluoromethyl and methoxy when n is 0, A is hydroxy, X and Y are both hydrogen, R is COOEt and R′ and R″ together form a group —(CH 2 ) 2 —, in free base or acid addition salt form.