Patent ID: 8055041

Claim:
A method of correcting motion for functional magnetic resonance imaging (fMRI), said method comprising: (a) having a plurality of images, wherein each of said images has a plurality of voxels, wherein said images are aligned, wherein said alignment corresponds said voxels of each of said images with said voxels of another of said images, and wherein said alignment provides one or more translational distances between said voxels in each of said images with said corresponding voxels in another of said images; (b) defining a time-series vector for each of said voxels, wherein said time-series vector represents the value of said corresponding voxels over a number N of said plurality of aligned images; (c) calculating a motion correction estimator for each of said voxels, wherein said motion correction estimator is calculated based on said time-series vector and a plurality of correction parameters, wherein said correction parameters can be different for each of said N images, wherein said correction parameters are based on said translational distances of said corresponding voxels, and wherein said correction parameters are: (i) approximately periodic in the size of the same said voxels; and (ii) approach zero if said translational distances approach zero; and (d) correcting the value of each of said voxels of said plurality of images based on said motion correction estimator and said time-series vector for each of said voxels.