Patent ID: 7064122

Claim:
A compound having the structure: wherein, Y is O; XR 2 is —N([CH 2 ] 7 CH 3 )C(O)NH(CH 2 ) 7 CH 3 , —N([CH 2 ] 6 CH 3 )C(O)NH(CH 2 ) 6 CH 3 , —NH(CH 2 ) q CH 3 , —NH(C 6 H 4 )O(C 6 H 5 ), —N(CH 3 )(CH 2 ) 5 CH 3 , —NHCH[(CH 2 ) 3 CH 3 ] 2 , —NHCH(CH 3 )[(CH 2 ] 5 CH 3 , or —N([CH 2 ] 7 CH 3 ) 2 ; q is an integer from 6 to 15; R 1 is H, substituted C 1 -C 15 alkyl, or unsubstituted C 2 -C 15 alkyl, C 1 -C 8 alkylaryl, —C(O)OR 4 , —C(O)NR 4 R 5 , —CR 6 R 6′ OR 4 , —CR 6 R 6′ OC(O)R 4 , —CR 6 R 6′ OC(O)NHR 7 , —C(O)NR 8 R 9 NR 8 R 9 , —N(R 5 )C(O)NHR 5 , or CH 2 R 4 ; R 3 is H, —CH 3 , —CH 2 OCH 3 or C 3 -C 10 cycloalkyl, wherein R 4 is H or a substituted or unsubstituted, straight chain or branched, C 6 -C 30 alkyl, aryl, —CH 2 -aryl, aryl —C 1 -C 30 alkyl, heteroaryl-C 1 -C 30 alkyl or C 3 -C 10 cycloalkyl; R 6 and R 6′ are each independently H, substituted or unsubstituted C 1 -C 6 alkyl, dialkyl or C 3 -C 10 cycloalkyl or together form a 3-7 membered cycloalkyl or aryl group; R 7 is H or substituted or unsubstituted C 1 -C 12 alkyl or C 3 -C 10 cycloalkyl; and R 8 and R 9 are each independently H, substituted or unsubstituted C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkylaryl, or NR 8 R 9 together form a substituted piperazine or piperidine ring or a dihydro-1H-isoquinoline ring system, or a specific enantiomer thereof, or a specific tautomer, or a pharmaceutically acceptable salt thereof.