Patent ID: 7700553

Claim:
A polypeptide fusion construct that inhibits signalling via NF-κB comprising: a polypeptide having a high transduction potential, and an amino acid sequence selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 7, SEQ ID NO: 14, SEQ ID NO: 16, SEQ ID NO: 30, SEQ ID NO: 31, SEQ ID NO: 32, SEQ ID NO: 33, SEQ ID NO: 34, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, and SEQ ID NO: 39, or a variant thereof having one amino acid substitution; wherein said polypeptide having a high transduction potential and said amino acid sequence are optionally linked by an amino acid spacer sequence.