Patent ID: 8716317

Claim:
Compound of the formula I: wherein A is a 5- or 6-membered mono- or a 9- or 10-membered bicyclic heterocycle, whereby R1, R2, SO2 and oxadiazolone groups are attached to a carbon atom; R1 is H, (C1-C8) alkyl, halogen, (C0-C4) alkylene —(C3-C7) cycloalkyl, (C0-C4) alkylene —0—(C0-C8) alkyl, or (C0-C4) alkylene —(C6-C10) aryl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R2 is H, (C1-C8) alkyl, halogen, (C0-C4) alkylene —(C3-C7) cycloalkyl, (C0-C4) alkylene —0—(C0-C8) alkyl, or (C0-C4) alkylene —(C6-C10) aryl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R3 is H, (C1-C8) alkyl, (C0-C4) alkylene —(C3-C7) cycloalkyl, or (C0-C4) alkylene —(C6-C 10) aryl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R4 is H, (Cl-C8) alkyl, (CO-C4) alkylene —(C3-C7) cycloalkyl, or (C0-C4) alkylene -(C6-C 10) aryl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R5 is H, (C1-C8) alkyl, (C0-C4) alkylene —(C3-C7) cycloalkyl, or (C0-C4) alkylene —(C6-C 10) aryl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R6 is H, (C1-C8) alkyl, (C0-C4) alkylene —(C3-C7) cycloalkyl, or (C0-C4) alkylene —(C6-C 10) aryl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F or R5 and R6 together with the carbon atom carrying them form a (C3-C7)cycloalkyl ring, wherein one carbon atom can be replaced by one heteroatom out of O, S, or N; R7 is H, halogen, (C1-C8) alkyl, (C0-C4) alkylene—0—(C0-C4) alkylene-H, or (C3-C7) cycloalkyl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R8 is H, halogen, (Cl-C8) alkyl, (C0-C4) alkylene—0—(C0-C4) alkylene-H, or (C3-C7) cycloalkyl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; R9 is H, halogen, (C1-C8) alkyl, (C0-C4) alkylene—0—(C0-C4) alkylene-H, or (C3-C7) cycloalkyl, wherein alkyl and alkylene are unsubstituted or 1- to 3-fold substituted by F; and X1, X2, X3, X4, X5 are independently N or CH; or stereoisomers, tautomers, and physiologically acceptable salts thereof.