Patent ID: 7157101

Claim:
A pharmaceutical composition comprising: (a) about 25 mg to about 100 mg of particulate eplerenone having a D 90 particle size of about 25 microns to about 400 microns, (b) about 0.5 to about 30 weight percent of one or more pharmaceutically acceptable disintegrants, (c) about 5 to about 99 weight percent of one or more pharmaceutically acceptable diluents, and (d) about 0.5 to about 25 weight percent of one or more pharmaceutically acceptable binding agents, wherein the composition is an immediate release composition wherein at least about 80% of the eplerenone is dissolved in vitro within about 30 minutes in 0.1N HCl at 37° C., and wherein the composition substantially disintegrates within about 30 minutes when placed in a water bath maintained at a temperature of 37° C.±2° C.