Patent ID: 8389573

Claim:
A compound selected from a compound of Formula (I): wherein R 1 is selected from CN, halo, NO 2 , CO 2 R 3 , C 1-6 alkyl, fluoro-substituted C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, OR 3 , SR 3 , SOR 3 , SO 2 R 3 , NR 3 R 4 , C(O)NR 3 R 4 , C(O)R 3 , OC(O)R 3 , NHC(O)R 3 , P(O)R 3 R 4 , —C═C—R 3 , —CR 3 ═CR 4 R 5 , aryl and heteroaryl; R 2 is selected from OC 1-6 alkyl, fluoro-substituted OC 1-6 alkyl, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl)(C 1-6 alkyl), SH and SC 1-6 alkyl; R 3 , R 4 and R 5 are independently selected from H, C 1-6 alkyl, fluoro-substituted C 1-6 alkyl, aryl and heteroaryl; and one of X and Y is C═O while the other is CH 2 , and if X is C═O then - - - adjacent to X represents a single bond and - - - adjacent to Y represents a double bond and if Y is C═O then - - - adjacent to Y represents a single bond and - - - adjacent to X represents a double bond; and pharmaceutically acceptable salts and solvates thereof, and mixtures thereof in any ratio, with the proviso that R 1 is not —OH or —OCH 3 .