Patent ID: 7304085

Claim:
A compound of the formula I: wherein: R 1 is selected from the group consisting of—OR 7 , and—NR 8 R 9 ; where R 7 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic; R 8 and R 9 are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic or, alternatively, R 8 and R 9 , together with the nitrogen atom pendent thereto, form a heterocyclic or substituted heterocyclic ring group; R 2 and R 12 are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, heterocyclic, and substituted heterocyclic; or, R 2 and R 12 , together with the carbon atom pendent thereto, form a cycloalkyl, substituted cycloalkyl, heterocyclic or substituted heterocyclic ring group; R 3 is selected from the group consisting of hydrogen and alkyl; or R 2 and R 3 , together with the nitrogen atom pendent to R 3 , form a heterocyclic or substituted heterocyclic ring group; each R 4 is selected from the group consisting of halo, nitro, amino, substituted amino, cyano and hydroxyl; Q is selected from the group consisting of oxygen, —S(O) q — where q is zero, one or two and —N(R 3 )— where R 3 is as defined above; X is selected from the group consisting of oxygen, sulfur, and ═NR 11 , where R 11 is hydrogen or alkyl: R 5 is alkylene or substituted alkylene; R 6 is selected from the group consisting of substituted aryl, and substituted heteroaryl; n is 0 to 3; or pharmaceutically acceptable salts thereof.