Patent ID: 7205303

Claim:
A compound of the formula: wherein: R 1 and R 2 are independently cycloalkyl or aryl and may be optionally substituted with 1 to 3 substituents selected from acetyl, alkyl, hydroxy, alkoxy, halogen, halogen substituted alkyl, phenyl, and phenyl substituted with alkyl, alkoxy, hydroxy, halogen, or CF 3 ; R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10 , are independently hydrogen, lower alkyl, or —C(O)R; in which R is —OR 11 or —NR 11 R 12 , where R 11 and R 12 are hydrogen or lower alkyl; or R 3 and R 4 , R 5 and R 6 , R 7 and R 8 , R 9 and R 10 , when taken together with the carbon to which they are attached, represent carbonyl; with the proviso that the maximum number of carbonyl groups is 1; and the maximum number of —C(O)NR 11 R 12 groups is 1; T is oxygen or sulfur; X is a covalent bond or —(CR 15 R 16 ) p —, in which R 15 and R 16 are hydrogen, lower alkyl, or —C(O)OR 17 and p is 1, 2 or 3, in which R 17 is hydrogen, lower alkyl, or phenyl substituted with alkyl, alkoxy, hydroxy, or halogen; Y 1 and Y 2 are independently —(CR 18 R 19 ) q —, in which q is 1, 2 or 3 and R 18 and R 19 are independently hydrogen, hydroxy, or lower alkyl; with the proviso that R 18 and R 19 are not hydroxy when q is 1; and Z is a covalent bond, —C(O)NR 20 —, or —NR 20 C(O)—, where R 20 is hydrogen or lower alkyl; with the provisos, that (a) when R 1 and R 2 axe optionally substituted phenyl and X is a covalent bond, Z is not a covalent bond, and (b) when Z —C(O)NR 20 , X is a covalent bond.