Patent ID: 7575574

Claim:
An implantable apparatus for infusing a plurality of medicating agents to a specific desired location at a tumor site for non-systemic treatment of a tumor, when implanted within a patient's body, comprising: an implantable pouch comprised of synthetic human skin having one or more collapsible and disintegratable chambers composed of a bioabsorbable material, the one or more chambers being structurally defined by a matrix, each one or more chambers storing a corresponding one of the plurality of the medicating agents in a macroscopic amount sufficient for tumor treatment, and wherein the chambers and the synthetic human skin are arranged and configured to substantially completely collapse and disintegrate within the patient's body with depletion of the plurality of medicating agents which is selectively dispensed from the chambers; where at least one of the plurality of medicating agents are stored in the corresponding one or more collapsible chambers; at least one implantable piezoelectric pump fabricated in the pouch which forms a skeleton of the pump, the pump being configured to transfer the at least one medicating agent to the patient, the skin being an implantable, syngeneic and biodegradable human skin substitute covering the pouch and pump; at least one implanted sensor to measure a local homeostatic response related to at least one of the plurality of medicating agents; and a processor coupled to the pump, disposed on a biodegradable substrate on or in the pouch and including a programmable memory having a tangible memory medium in which is stored instructions for controlling the processor to differentiate malignant versus normal cells as determined from at least one biometric measurement from the at least one implanted sensor communicated to the tumor and coupled to the processor, where the processor selectively controls the at least one pump to selectively adjust the scheduling with which the medicating agents are delivered in response to selective user commands delivered to processor and alterable during a treatment process after implantation.