Patent ID: 7427370

Claim:
A process for producing at least one Grignard compound, said process comprising reacting magnesium in a liquid reaction medium under a protective gas atmosphere with microwave irradiation with at least one aromatic halogen compound of the formulae I or II: in which n in formula I represents 1, 2 or 3; X in formulae I and II represents F, Cl, Br or I; and R in formulae I and II represents a member selected from the group consisting of F, Cl, Br, I, C 1-5 -alkyl optionally at least mono-substituted with F, C 1-5 -alkoxy, NO 2 , N(R 1 ) 2 , CON(R 1 ) 2 , SR 1 , SOR 1 , SO 2 R 1 , SO 2 N(R 1 ) 2 , a group of the Formula III to VI: and an aryl or heteroaryl group, which is optionally at least mono-substituted with R′; wherein A and B are identical or different and represent O, S or NH; R 1 represents in each case C 1-6 -alkyl; or in formula III the two R 1 groups optionally combine to form —CH 2 —CH 2 — or —CH 2 —CH 2 —CH 2 —; R 2 , R 3 , R 4 , R 5 , R 6 and R 7 independently represent H, C 1-6 -alkyl, optionally substituted aryl or optionally substituted heteroaryl; and R′ represents F, Cl, Br, I, C 1-5 -alkyl optionally at least mono-substituted with F, C 1-5 -alkoxy, NO 2 , N(R 1 ) 2 , CON(R 1 ) 2 , SR 1 , SOR 1 , SO 2 R 1 , SO 2 N(R′) 2 , or a group of the Formula III to VI.