Patent ID: 7056527

Claim:
A patch comprising an adhesive layer formed on one surface of a flexible support, wherein said adhesive layer consists essentially of a drug, an absorption enhancer and an adhesive wherein: (i) said drug is buprenorphine hydrochloride and/or buprenorphine, and (ii) said absorption enhancer consists essentially of a mixture of polyoxyethylene mono fatty acid ester having 6 to 20 of oxyethylene units and 12 to 18 of carbor number of fatty acid ester, and at least one selected from the group consisting of liquid higher fatty acid ester, 60 to 180 of molecular weight of liquid poly hydric alcohol, lactic acid and triacetin, and (iii) said adhesive is an acrylic-based adhesive, wherein the amount of the polyoxyethylene mono fatty acid ester is 1 to 20% by weight based on the total weight of the adhesive layer, the amount of at least one component selected from the group consisting of higher fatty acid ester, poly hydric alcohol, lactic acid and triacetin is 5 to 49% by weight based on the total weight of the adhesive layer, and the total amount of the absorption enhancer mixture is 6 to 50% by weight based on the total weight of the adhesive layer.