Patent ID: 8883225

Claim:
A method of making a water-soluble pharmaceutical gel composition of isomerized hops extract, comprising the steps: heating a water-soluble non-ionic surfactant in a container to a temperature of about 90° F. to about 250° F., while mixing the non-ionic surfactant until it is clear, wherein the non-ionic surfactant is selected from the group consisting of monoglycerides, diglycerides, triglycerides, mono-fatty acid esters of polyethylene glycol, di-fatty acid esters of polyethylene glycol, sorbitan fatty acid esters, polyglycolyzed glycerides, triblock copolymers, and mixtures thereof; heating a hops extract to a temperature of about 120° F. to 250° F. such that isomerization of the hops extract occurs to yield isomerized hops; and mixing an amount of the hops extract which includes the isomerized hops extract with the non-ionic surfactant so as to yield from 0.2 wt % to 70 wt % hops extract which includes the isomerized hops extract and from 30 wt % to 99.8 wt % non-ionic surfactant, wherein the hops extract which includes the isomerized hops extract is sufficiently dispersed or dissolved in the non-ionic surfactant to yield the water-soluble pharmaceutical gel composition of isomerized hops extract which contains no visible particles.