Patent ID: 7442839

Claim:
A compound of formula (I): or a salt, solvate, or physiologically functional derivative thereof, wherein: m is an integer of from 2 to 8; and n is an integer of from 3 to 11; with the proviso that m+n is 5 to 19; R 1 is SR 6 , SOR 6 , or SO 2 R 6 , wherein R 6 is a C 3-7 cycloalkyl or C 3-7 cycloalkenyl group; R 2 and R 3 are independently selected from hydrogen, C 1-6 alkyl, C 1-6 alkoxy, halo, phenyl, and C 1-6 haloalkyl; R 4 and R 5 are independently selected from hydrogen and C 1-4 alkyl with the proviso that the total number of carbon atoms in R 4 and R 5 is not more than 4; Ar is a group selected from wherein R 8 represents hydrogen, halogen, —(CH 2 ) q OR 11 , —NR 11 C(O)R 12 , —NR 11 SO 2 R 12 , —SO 2 NR 11 R 12 , —NR 11 R 12 , —OC(O)R 13 or OC(O)NR 11 R 12 , and R 7 represents hydrogen, halogen, or C 1-4 alkyl; or R 8 represents —NHR 14 and R 7 and —NHR 14 together form a 5- or 6-membered heterocyclic ring; R 9 represents hydrogen, halogen, —OR 11 or —NR 11 R 12 ; R 10 represents hydrogen, halogen, haloC 1-4 alkyl, —OR 11 , —NR 11 R 12 , —OC(O)R 13 or OC(O)NR 11 R 12 ; R 11 and R 12 each independently represents hydrogen or C 1-4 alkyl, or in the groups —NR 11 R 12 , —SO 2 NR 11 R 12 and —OC(O)NR 11 R 12 , R 11 and R 12 independently represent hydrogen or C 1-4 alkyl or together with the nitrogen atom to which they are attached form a 5-, 6- or 7-membered nitrogen-containing ring, R 13 represents an aryl group which may be unsubstituted or substituted by one or more substituents selected from halogen, C 1-4 alkyl, hydroxy, C 1-4 alkoxy or halo C 1-4 alkyl; and q is zero or an integer from 1 to 4.