Patent ID: 8734868

Claim:
A method of treating diabetes-related symptoms of a patient comprising: administering a therapeutically effective amount of a pomegranate composition to a patient to affect at least one diabetes-related symptom, wherein said pomegranate composition is obtained by a process comprising: crushing, squeezing, and enzymatically treating whole fruits of pomegranate including inner and outer peels and seeds to yield a juice component and an insoluble by-product component; separating the juice component from the insoluble by-product component; resuspending the insoluble by-product component in an aqueous medium; crushing, squeezing, and mixing the resuspended by-product component to yield a soluble portion and an insoluble portion; separating the soluble portion from the insoluble portion; and combining the soluble portion with the juice component to produce the pomegranate composition, wherein said pomegranate composition comprises about 1979 mg/L of tannins, and wherein said therapeutically effective amount of said pomegranate composition comprises an amount sufficient to result in anti-atherogenic effects with a significant reduction in oxidative stress in said patient's serum and monocytes-macrophages, as well as in macrophage uptake of Ox-LDL.