Patent ID: 7045526

Claim:
A compound of formula I wherein one of R 1 and R 2 is chosen from unsubstituted (C 3 –C 9 )-cycloalkyl, and (C 3 –C 9 )-cycloalkyl which is substituted by at least one identical or different substituents chosen from (C 1 –C 4 )-alkyl, benzyl, hydroxy, amino, H—CO—O—, (C 1 –C 4 )-alkyl-CO—O—, (C 1 –C 4 )-alkyl-O—CO—O—, H—CO—NH—, (C 1 –C 4 )-alkyl-CO—NH—, (C 1 –C 4 -alkyl-O—CO—NH—, phenyl-CO—NH—, (C 1 –C 4 )-alkyl-SO 2 —NH—, and phenyl-SO 2 -NH—, and the other of R 1 and R 2 is hydrogen, wherein phenyl groups, and benzyl group present in R 1 and R 2 are unsubstituted or substituted on the aromatic ring by at least one identical or different substituents chosen from halogen, (C 1 –C 4 )-alkyl, phenyl CF 3 , NO 2 , OH, —O—(C 1 –C 4 )-alkyl, —O—(C 2 –C 4 )-alkyl-O—(C 1 –C 4 )-alkyl, (C 1 –C 2 )-alkylenedioxy, NH 2 , —NH—(C 1 –C 4 )-alkyl, —N((C 1 –C 4 )-alkyl) 2 , —NH—CHO, —NH—CO—(C 1 –C 4 )-alkyl, —CN, —CO—NH 2 , —CO—NH—(C 1 –C 4 )-alkyl, —CO—N((C 1 –C 4 )-alkyl) 2 , —CO—OH, —CO—O—(C 1 –C 4 )-alkyl, —CHO and —CO—(C 1 –C 4 -alkyl; wherein R 3 is aryl but cannot be unsubstituted phenyl; wherein aryl is chosen from unsubstituted napthyl and phenyl, naphthyl and heteroaryl, all of which are unsubstituted or substituted by at least one identical or different substituents chosen from halogen, (C 1 –C 4 )-alkyl, phenyl, OF 3 , NO 2 , OH, —O—(C 1 –C 4 )-alkyl, —O—(C 2 –C 4 )-alkyl-O—(C 1 –C 4 )-alkyl, (C 1 –C 2 )-alkylenedioxy, NH 2 , —NH—(C 1 –C 4 )-alkyl, —N((C 1 –C 4 )-alkyl) 2 , —NH—CHO, —NH—CO—(C 1 –C 4 )-alkyl, —CN, —CO—NH 2 , —CO—NH—(C 1 –C 4 )-alkyl, —CO—N((C 1 –C 4 )-alkyl) 2 , —CO—OH, —CO—O—(C 1 –C 4 )-alkyl, —CHO and —CO—(C 1 –C 4 )-alkyl; wherein heteroaryl is chosen from a radical of a monocyclic 5-membered aromatic heterocycle, a radical of a monocyclic 6-membered aromatic heterocycle, a radical of a bicyclic 8-membered aromatic heterocycle, a radical of a bicyclic 9-membered aromatic heterocycle, and a radical of a bicyclic 10-membered aromatic heterocycle, each of which contain at least one identical or different ring heteroatoms chosen from N, O and S; and in any stereoisomeric form, or mixtures thereof in any ratio, or their physiologically acceptable salts.