Patent ID: 8354454

Claim:
A compound of formula I, or a pharmaceutically acceptable salt thereof: wherein R 1 is selected from H and C 1-4 alkyl, which is optionally substituted with 1-5 F groups; Each R 2 is independently selected from the group consisting of halogen, —CN, C 1-4 alkyl, and —OC 1-4 alkyl, wherein C 1-4 alkyl and —OC 1-4 alkyl are optionally substituted with 1-5 halogens; R 3 is selected from the group consisting of H, halogen, C 1-4 alkyl, and —OC 1-4 alkyl, wherein C 1-4 alkyl and —OC 1-4 alkyl are optionally substituted with 1-5 halogens; R 4 and R 5 are each independently selected from the group consisting of halogen, C 1-4 alkyl, and —OC 1-4 alkyl, wherein C 1-4 alkyl and —OC 1-4 alkyl are optionally substituted with 1-5 halogens; R 6 is selected from H and C 1 -C 5 alkyl optionally substituted with 1-5 halogens and optionally substituted with 1-2 phenyl groups, wherein phenyl is optionally substituted with 1-3 groups independently selected from halogen, C 1 -C 3 alkyl, —OC 1 -C 3 alkyl, CF 3 , and —OCF 3 ; R 7 is selected from H and C 1 -C 3 alkyl optionally substituted with 1-3 F; X is selected from —OZ and —SZ, wherein Z is selected from: (a) C 1 -C 5 alkyl which optionally includes an —O— atom between 2 adjacent carbon atoms, wherein C 1 -C 5 alkyl is optionally substituted with 1-5 halogens and is optionally substituted with 1-2 substituent groups independently selected from phenyl, —C(═O)OR 6 , —OP(═O)(OR 7 ) 2 , and —P(═O)(OR 7 ) 2 , wherein phenyl is optionally substituted with 1-3 groups independently selected from halogen, —C(═O)OR 7 , and C 1 -C 3 alkyl optionally substituted with 1-3 halogens; and (b) phenyl, wherein phenyl is optionally substituted with 1-3 groups independently selected from halogen; C 1 -C 5 alkyl; —OC 1 -C 5 alkyl; —C(═O)OR 7 ; and C 5 -C 7 cycloalkyl optionally substituted with 1-2 groups independently selected from halogen, C 1 -C 3 alkyl, —OC 1 -C 3 alkyl, CF 3 , and —OCF 3 ; wherein C 1 -C 5 alkyl and —OC 1 -C 5 alkyl are optionally substituted with 1-5 F and are optionally substituted with 1-2 groups independently selected from —C(═O)OR 7 , —N(R 7 ) 2 , —OP(═O)(OR 7 ) 2 , and —P(═O)(OR 7 ) 2 ; a and b are integers independently selected from 0-4; and c is an integer from 0-2.