Patent ID: 7414051

Claim:
A compound of formula I wherein X is a bond, O, S, NR or CONR; m is 0 or an integer of 1; R is H or an optionally substituted alkyl group; R 1 and R 7 are each independently H or an optionally substituted alkyl group; R 2 is an alkyl, cycloalkyl, aryl or heteroaryl group each group optionally substituted or an optionally substituted 8- to 13-membered bicyclic or tricyclic ring system having a N atom at the bridgehead and optionally containing 1, 2 or 3 additional heteroatoms selected from N, O or S; R 3 and R 4 are each independently H, or an optionally substituted alkyl group; n is 0 or an integer of 2, 3, 4, 5, or 6; R 5 and R 6 are each independently H or an alkyl, alkenyl, alkynyl or cycloalkyl, group each group optionally substituted or R 5 and R 6 may be taken together with the atom to which they are attached to form an optionally substituted 3- to 7-membered ring optionally containing an additional heteroatom selected from NR, O or S; R 8 is H, halogen, OR 9 , or an optionally substituted alkyl group; and R 9 is H, alkyl or haloalkyl; or a stereoisomer thereof or a pharmaceutically acceptable salt thereof, wherein the optional substituents are selected from the group consisting of halogen atoms, nitro, cyano, thiocyanato, hydroxyl, alkyl, haloalkyl, alkoxy, haloalkoxy, amino, alkylamino, dialkylamino, formyl, alkoxycarbonyl, carboxyl, alkanoyl, alkylthio, alkylsulphinyl, alkylsulphonyl, carbamoyl, alkylamido, phenyl, phenoxy, benzyl, benzyloxy, heterocyclyl and cycloalkyl groups.