Patent ID: 6849723

Claim:
A compound having Formula: wherein: Z is a phosphodiester or phosphorothioate intersugar linkage; each T 1 and T 2 is, independently, —OH, —OR 1 , —CH 2 R 1 , —NH(R 1 ), —SH, —SR 1 , or a blocked hydroxyl; R 1 is C 1 -C 12 alkyl; B X is a heterocyclic base; and X is F, —OCH 2 CH 2 OCH 3 or —OCH 2 CH 2 CH 2 NH 2 when Z is a phosporothioate intersugar linkage or X is —OCH 2 CH 2 OCH 3 or —OCH 2 CH 2 CH 2 NH 2 when Z is a phosphodiester intersugar linkage.