Patent ID: 8389222

Claim:
A method for obtaining and reporting a profile of at least one selected apolipoprotein biomarker in a biological sample, comprising: a) obtaining the biological sample; b) treating a surface with an antibody receptor molecule; c) applying at least one antigen receptor to the treated surface to bind with the bound antibody receptor molecule, said at least one antigen receptor specific for apolipoprotein biomarker; d) applying the biological sample directly to the treated surface to bind with the at least one selected apolipoprotein biomarker isoform profile; e) removing unbound components of the biological sample; f) measuring said apolipoprotein biomarker profile, by directly analyzing the sample by spectrometry; and g) preparing the profile using the simultaneous analysis wherein the said apolipoprotein biomarker profile comprises Apo CI, Apo CII, Apo CIII, Apo CIV, Apo A1, Apo A11, Apo AIV, Apo AV, Apo B48, Apo B100, Apo D, Apo E, Apo F, Apo G, Apo H, Apo J, Apo L and Apo M.