Patent ID: 7786316

Claim:
A metalloprotein inhibitor of formula (IA) or (IB): wherein X is O or S and wherein R 1 is a group of the formula —C(═O)NHR 1′ , wherein R 1′ is biphenyl, biphenyl(C 1 -C 6 )alkyl, or phenoxyphenyl, wherein the —C(═O) group of R 1 is bonded directly to a ring carbon atom, wherein any phenyl can be independently substituted; and wherein R 2 is hydrogen, or is an unsubstituted (C 1 -C 6 )alkyl, (C 3 -C 6 )cycloalkyl, (C 3 -C 6 )cycloalkyl-(C 1 -C 6 )alkyl), (C 6 -C 10 )aryl, (C 6 -C 10 )aryl-(C 2 -C 10 )alkyl, and R 3 is hydrogen, or is an unsubstituted (C 1 -C 6 )alkyl, hydroxy(C 1 -C 6 )alkyl or (C 1 -C 6 )alkanoyloxy, and R 4 , when present, is hydrogen, or is an unsubstituted (C 1 -C 6 )alkyl, (C 3 -C 6 )cycloalkyl, (C 3 -C 6 )cycloalkyl-(C 1 -C 6 )alkyl), (C 6 -C 10 )aryl, or (C 6 -C 10 )aryl-(C 2 -C 10 )alkyl; provided that R 2 and R 3 are not both hydrogen; and provided that when X is O for a compound of formula (IA) that R 3 is not methyl; or a pharmaceutically-acceptable salt thereof.