Patent ID: 8299087

Claim:
A method of inhibiting an activity of a JAK kinase, comprising contacting the JAK kinase with an amount of a compound according to formula I effective to inhibit an activity of the JAK kinase or therapeutically acceptable salt thereof, wherein: ring A is phenyl; ring B is benzofuranyl; q is 0, 1, 2 or 3; p is 0; R is hydrogen or lower alkyl; X is selected from the group consisting of hydrogen, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, amino, substituted amino, carboxyl, carboxyl ester, cyano, halo, nitro, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkynyl, substituted cycloalkynyl; Y is a covalent bond; alk is a covalent bond; R 1 is —C(O)NR 4 R 5 each R 2 independently is selected from the group consisting of alkyl, substituted alkyl, alkoxy, substituted alkoxy, amino, substituted amino, aryl, substituted aryl, aryloxy, substituted aryloxy, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heteroaryloxy, substituted heteroaryloxy, heterocyclic, substituted heterocyclic, heterocyclyloxy, substituted heterocyclyloxy, carboxyl, carboxyl ester, alkynyl, substituted alkynyl, hydroxyl, acyl, halo, acylamino, aminocarbonyl, and cyano; R 4 is hydrogen; and R 5 is morpholinoethyl.