Patent ID: 8551524

Claim:
A pharmaceutical composition for treating diabetes consisting of: a) a slow release core comprising metformin or a pharmaceutically acceptable salt thereof, and optionally one pharmaceutically acceptable excipient, and b) an immediate release coating comprising a dipeptidyl peptidase IV inhibitor or a pharmaceutically acceptable salt thereof; wherein the said composition exhibits a dissolution profile such that after two hours from 0 to about 25 percent of metformin is released, after four hours from about 10 to about 45 percent of metformin is released, after eight hours from about 30 to about 90 percent of metformin is released, after twelve hours not less than 50 percent of metformin is released, and after sixteen hours not less than 60 percent of metformin is released, when tested in a USP type 1 apparatus, at pH 2.0 in a HCI-0.3M KCI buffer solution.