Patent ID: 7629368

Claim:
A method for treating prostate cancer, bladder cancer, colon cancer, or human adenocarcinoma cancer in a patient in need thereof comprising administering to the patient in need thereof an effective amount of a nitroderivative or salts thereof having the following general formula (I): A—X 1 —L—(W) p —NO 2 (I) wherein: p is an integer equal to 1 or 0; A=R—T 1 —, wherein R has the following formula: T 1 =(CO) t or (X) t , wherein X=O, S or NR 1C , wherein R 1C is H or a linear or branched alkyl, having from 1 to 5 carbon atoms, t and t′ are integers and equal to zero or 1, with the proviso that t=1 when t′=0; t=0 when t′=1; X 1 =−T B —Y—T B1 — wherein T B and T B1 are equal or different; T B =(GO) when t=0, T B —X when t′=0, X being as above; T B1 =(CO) tx , or (X) txx , wherein tx and txx have the value of 0 or 1; with the proviso that tx=1 when txx=0; and tx=0 when txx=1; X is as above; Y is selected from the following: wherein: nIX is an integer in the range 0-3; nIIX is an integer in the range 1-3; R TIX , R TIX , R TIIX , R TIIX′ , equal to or different from each other, are H or a C 1 -C 4 linear or branched alkyl; Y 3 is the following bivalent radical an alkylene group R′ wherein R′ is a C 1 -C 20 linear or branched, optionally substituted with one or more of the following groups: —NHCOR 3 wherein R 3 is a C 1 -C 5 linear or branched radical, —NH 2 , or —OH; wherein n3 is an integer from 0 to 3 and n3′ is an integer from 1 to 3; wherein n3 and n3′ have the above meaning; wherein R 4 is hydroxy, hydrogen, or R 5 O— alkoxy, wherein R 5 is a C 1 -C 10 linear, branched or cyclic alkyl group; and R 2 is a C 2 -C 10 linear or branched alkenylene group which can contain one or more double bonds; or wherein R 1f =H, CH 3 , and nf is an integer from 0 to 6; L=covalent bond, CO or X, X being as defined above; W=Y T O wherein Y T has the same meanings of Y as defined above, and Y T is equal to or different from Y.