Patent ID: 8237131

Claim:
A system for carrying out fibre-type multiphoton imaging of a sample, comprising: a pulsed laser for generating a multiphoton excitation laser beam; an image guide comprising a plurality of optical fibres to allow the sample to be illuminated by a point-by-point scanning, a compensation device configured to compensate for non-linear effects and dispersion effects of excitation pulses in the image guide, the compensation device comprising: a section of optical fibre followed by a dispersive line, wherein the section of optical fibre comprises an optimized length and a mode diameter greater than the image guide fibre mode diameters, and wherein the optimized length is a function of at least a wavelength of the laser beam, a power and a width of pulses at an input and an output of the image guide, and a length of the image guide; wherein the compensation device is arranged between the pulsed laser and the image guide; and a scanning device positioned in the system after the section of optical fibre of the compensation device and before the image guide, for directing in succession the multiphoton excitation laser beam into individual fibres of the image guide.