Patent ID: 7491745

Claim:
A method for treating cervical cancer, prostate cancer, ovarian cancer, lung cancer, breast cancer, colorectal cancer, or melanoma, comprising administering to a patient in need of such treatment a therapeutically effective amount of a compound of Formula (V): or a pharmaceutically acceptable salt thereof, wherein, in the compound of Formula (V): each R 1 is selected from the group consisting of —H, —CH 3 , —CH 2 CH 3 , —CH 2 C 6 H 5 , —C(O)OC(CH 3 ) 3 , —C(O)OCH 2 C 6 H 5 , and —C(O)CH 3 ; R 2 is selected from the group consisting of —H, C 1 -C 12 straight chain alkyl, —CH 2 C 6 H 5 , —SiR 10 R 11 R 12 , —C(O)CH 3 , —C(O)C 6 H 5 , -2-tetrahydropyranyl, —OCH 2 OCH 3 , and —C(O)OCH 2 CCl 3 ; R 7 is selected from the group consisting of —H, C 1 -C 15 straight chain alkyl, —(CH 2 ) 9 CH═CH 2 , —(CH 2 ) 6 F, —(CH 2 ) 5 OC 6 H 5 , —(CH 2 ) 6 OH, —(CH 2 ) 7 CN, —CH 2 CH 2 C 6 H 5 , —(CH 2 ) 4 COOH, —(CH 2 ) 5 COOH, —(CH 2 ) 5 COOMe, —(CH 2 ) 11 COOH, —(CH 2 ) 12 COOH, —(CH 2 ) 12 OH, —(CH 2 ) 13 OH, —(CH 2 ) 11 CN, —(CH 2 ) 11 OC(O)NH 2 , —(CH 2 ) 11 COOEt, —C(O)(CH 2 ) 9 CH 3 , —(CH 2 ) 5 C(O)N(CH 2 CH 2 ) 2 O, C 3 -C 7 cycloalkyl, —C 6 H 5 , 2-pyrrolyl, -3-pyrrolyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furanyl, and 3-furanyl, the phenyl being substituted with one or more halo, methyl, methoxyl, hydroxyl, methoxycarbonyl or trifluoromethyl groups; R 8 is selected from the group consisting of —H, C 1 -C 11 straight chain alkyl, —(CH 2 ) 4 COOEt, and —C 6 H 5 ; when R 7 is other than 2-pyrrolyl, then R 9 is selected from the group consisting of —H, —CH 3 , —CH 2 CH 3 , and —CH 2 CH 2 CH 3 ; when R 7 is 2-pyrrolyl, then R 9 is selected from the group consisting of —H, —CH 3 , —CH 2 CH 3 , —CH 2 CH 2 CH 3 , and —OCH 3 ; R 10 is selected from the group consisting of C 1 -C 4 straight or branched chain alkyl and —C 6 H 5 ; R 11 and R 12 are independently selected from the group consisting of —CH 3 , —CH 2 CH 3 , and —C 3 H 7 ; R 16 is selected from the group consisting of —H, —CH 3 , —CH 2 CH 2 CH 3 , and —(CH 2 ) 6 CH 3 ; and R 17 is selected from the group consisting of —H, —CN, —COOMe, —COOEt, and —COOH.