Patent ID: 7183297

Claim:
A compound of formula (I): wherein R 1 is a phenyl group which may be optionally substituted; R 2 is selected from hydrogen, C 1-6 alkyl and —(CH 2 ) q —C 3-7 cycloalkyl; R 3 is the group —NH—CO—R 4 ; R 4 is selected from hydrogen, C 1-6 alkyl, C 1-6 alkoxy, —(CH 2 ) q —C 3-7 cycloalkyl, trifluromethyl, —(CH 2 ) r phenyl optionally substituted by R 5 and/or R 6 , —(CH 2 ) r heteroaryl optionally substituted by R 5 and/or R 6 , —(CH 2 ) r heterocyclyl optionally substituted by R 5 and/or R 6 and —(CH 2 ) r fused bicyclyl optionally substituted by R 5 and/or R 6 ; R 5 is selected from C 1-6 alkyl, C 1-6 alkoxy, —(CH 2 ) q —C 3-7 cycloalkyl, —CONR 7 R 8 , —NHCOR 8 , —SO 2 NHR 7 , —NHSO 2 R 8 , halogen, —(CH 2 ) s NR 9 R 10 , oxy, trifluoromethyl, phenyl optionally substituted by one or more R 6 groups and heteroaryl wherein the heteroaryl may be optionally substituted by one or more R 6 groups; R 6 is selected from C 1-6 alkyl, C 1-6 alkoxy, halogen, trifluromethyl and —NR 9 R 10 ; or R 5 and R 6 , together with the carbon atoms to which they are bound, form a five- or six-membered saturated or unsaturated ring to give a fused bicyclic ring system, wherein the ring that is formed by R 5 and R 6 may optionally contain one or two heteroatoms selected from oxygen, nitrogen and sulfur; R 7 is selected from hydrogen, C 1-6 alkyl and phenyl wherein the phenyl group may be optionally substituted by one or more R 6 groups; R 8 is selected from hydrogen and C 1-6 alkyl; or R 7 and R 8 , together with the nitrogen atom to which they are bound, form a five- to six-membered heterocyclic ring optionally containing one additional heteroatom selected from oxygen, sulfur and N—R x , wherein the ring may be substituted by up to two C 1-6 alkyl groups; R x is selected from hydrogen and methyl; R 9 is selected from hydrogen, C 1-6 alkyl and —(CH 2 ) q —C 3-7 cycloalkyl optionally substituted by C 1-6 alkyl; R 10 is selected from hydrogen and C 1-6 alkyl; or R 9 and R 10 , together with the nitrogen atom to which they are bound, form a three- to seven-membered heterocyclic ring optionally containing one additional heteroatom selected from oxygen, sulfur and N—R x , wherein the ring may contain up to one double bond and the ring may be substituted by one or more R 11 groups; R 11 is selected from C 1-6 alkyl, oxy, —CH 2 OC 1-6 alkyl, trichloromethyl and —N(C 1-6 alkyl) 2 ; U is selected from methyl and halogen; W is selected from methyl and chloro; X and Y are each selected independently from hydrogen, methyl and halogen; m is selected from 0, 1, 2, 3 and 4, and may be optionally substituted with up to two groups selected independently from C 1-6 alkyl; n is selected from 0, 1 and 2; q is selected from 0, 1 and 2; r is selected from 0 and 1; s is selected from 1, 1, 2 and 3; or a pharmaceutically acceptable salt or solvate thereof.