Patent ID: 7423157

Claim:
A compound of formula (I) represented by the formula wherein R represents phenyl, naphthyl, thienyl, furyl, thiazolyl, oxadiazolyl, thiadiazolyl, imidazolyl, pyrazolyl, pyridinyl, pyrimidinyl, benzothienyl, benzofuryl, indolyl, or benzisoxazolyl, optionally substituted by up to four substituents independently selected from alkyl, halo-lower alkyl, phenyl, optionally substituted heteroaryl, hydroxy, lower alkoxy, lower alkoxy-lower alkoxy, amino, monoalkylamino, dialkylamino, aminocarbonylamino wherein each of the two amino groups is optionally substituted by alkyl, alkenyl, alkinyl, heterocyclylcarbonylamino wherein heterocyclyl is bound via a nitrogen atom, lower alkoxycarbonylamino, lower alkylcarbonylamino wherein alkyl is optionally substituted by alkoxy or optionally substituted amino; lower alkenylcarbonylamino wherein alkenyl is optionally substituted by alkoxy or optionally substituted amino; lower alkylsulfinyl, lower alkylsulfonyl, lower alkylcarbonyl, carboxy, lower alkoxycarbonyl, cyano and halogen; and wherein two adjacent substituents on said groups represented by R may form a 5 or 6 membered carbocyclic or heterocyclic ring; X represents oxygen or a group C═Y, wherein Y stands for oxygen; Q represents N; R 1 represents a group NR 10 R 11 or OR 12 ; R 2 represents hydrogen, lower alkyl or amino; R 3 , R 4 , R 5 and R 6 , independently of each other, represent hydrogen, lower alkyl, halo-lower alkyl, cyano-lower alkyl, carboxy-lower alkyl, hydroxy, lower alkoxy, carboxy, lower alkoxycarbonyl, cyano or halogen; R 10 and R 11 , independently of each other, represent hydrogen, cyano-lower alkyl, carboxy-lower alkyl or lower alkylcarbonyl; R 12 is hydrogen; tautomers and pharmaceutically acceptable salts thereof.