Patent ID: 6960572

Claim:
A compound having the structure: or pharmaceutically acceptable salt or ester or salt of such ester thereof, wherein R A is hydrogen or an aliphatic moiety; R B is an aryl or -(alkyl)aryl group that contains a phosphorous containing moiety; X is O, S or NR H ; each occurrence of R C and R D is independently hydrogen, an aliphatic or heteroaliphatic moiety, halogen, —CN, —S(O) n R J , —NO 2 , —COR J , —CO 2 R J , —NR J COR J , —NR J (CO)NR J R J , —NR J CO 2 R J , —CONR J R J , —CO(NOR J )R J , or —ZR J , wherein Z is —O—, —S—, or NR K ; R H is hydrogen, hydroxy, —S(O) n R J , —COR J , —CO 2 R J , —CONR J R J , —CO(NOR J )R J , or an aliphatic, heteroaliphatic, aryl or heteroaryl moiety; q is 0-4 and p is 0-4, with the limitation that the sum of q and p is 0-4; wherein each occurrence of R J and R K is independently hydrogen, —COR J , —CO 2 R J , —CONR J R J , —CO(NOR J )R J , or an aliphatic, heteroaliphatic, aryl or heteroaryl moiety, and n is 1 or 2; and with the proviso that if R B is a tetralinyl or naphthalenyl moiety and R B contains only one phosphorus-containing moiety, the phosphorus-containing moiety is not —OPO(OH) 2 , —CH 2 OPO(OH) 2 or —PO(OH) 2 .