Patent ID: 8071130

Claim:
A solid preparation comprising the following part (1) and part (2): (1) a part containing coated particles in which particles containing pioglitazone or a salt thereof are coated with lactose; and (2) a part containing glimepiride, wherein part (1) the coated particles are a granulated material obtained by granulating pioglitazone or a salt thereof, an excipient and a disintegrant with a dispersion of a binder and lactose in a solvent, and the amount of lactose coating the particle containing pioglitazone or a salt thereof is 5 to 50 parts by weight based on 100 parts by weight of the particle; wherein part (2) is a composition comprising a granulated material obtained by granulating an excipient with a dispersion of glimepiride, a surfactant, a coloring agent and a binder in a solvent, said composition also comprising an excipient, a disintegrant and a lubricant; and said solid preparation is a multilayer tablet obtained by tabletting the part (1) and the part (2) in the form of a laminate.