Patent ID: 8440464

Claim:
A method for evaluating or selecting a test substance that regulates an animal's blood adiponectin level, comprising the following steps (A) to (E): (A) a step of administering a test substance to an experimental animal that is a rat; (B) a step of inducing sleep deprivation in the experimental animal; (C) a step of measuring the animal's blood adiponectin level after sleep deprivation; (D) a step of comparing the animal's blood adiponectin level after sleep deprivation to a blood adiponectin level in a control animal after sleep deprivation, wherein the control animal did not receive the test substance; and (E) a step of evaluating or selecting a test substance that changes the experimental animal's blood adiponectin level relative to that of the control animal in step (D) as a substance that regulates blood adiponectin level.