Patent ID: 8536173

Claim:
A compound corresponding to formula (I): in which: A represents a bond, an oxygen atom or an —O—CH 2 — group, Ar 1 represents a phenyl or heteroaryl group, Ar 2 represents a phenyl group, a heteroaryl group or a heterocycloalkyl group, R 1a,1b,1c and R 2a,2b,2c , which may be identical or different, each represent a hydrogen or halogen atom or an alkyl group, cycloalkyl, -alkyl-cycloalkyl optionally substituted with one or more halogen atoms; —OR 5 ; hydroxy-alkyl; alkoxy-alkyl; alkoxy-alkoxy; haloalkyl; —O-haloalkyl; oxo; —CO-alkyl; —CO-alkyl-NR 6 R 7 ; —CO-haloalkyl; —COOR 5 ; alkyl-COOR 5 ; —O-alkyl-COOR 5 ; —SO 2 -alkyl; —SO 2 -cycloalkyl; —SO 2 -alkyl-cycloalkyl; —SO 2 -alkyl-OR 5 ; —SO 2 -alkyl-COOR 5 ; —SO 2 -alkyl-NR 6 R 7 ; —SO 2 -haloalkyl; alkyl-SO 2 -alkyl; —SO 2 —NR 6 R 7 ; —SO 2 -alkyl-alkoxy-alkoxy; —CONR 6 R 7 ; -alkyl-CONR 6 R 7 or —O-alkyl-NR 6 R 7 , or R 1a , R 1b , R 1c are bound respectively to R 2a , R 2b , R 2c and to the carbon atom that bears them and represent —O-alkyl-O—; R 3 represents a hydrogen atom or an alkyl group, R 4 represents a group —CONR 6 R 7 ; hydroxy-alkyl substituted with a haloalkyl group; -alkyl-NH—SO 2 -alkyl; —NH—SO 2 -alkyl; —O—SO 2 —NR 6 R 7 ; -alkyl-CO—NR 6 R 7 ; —O-alkyl-CO—NR 6 R 7 ; -alkyl-NR 6 R 7 ; —O—CO—NR 6 R 7 ; alkyl-heteroaryl; heteroaryl optionally substituted with an alkyl group; alkoxy-imino; —CO—NH—NH—CO-alkyl; provided that R 4 is in cis position relative to the urea substituent on the adamantyl ring when it represents the group —CONR 6 R 7 and that R 6 and R 7 each represent hydrogen, an -alkyl or -alkyl-phenyl group; R 5 represent hydrogen, an alkyl group or an -alkyl-phenyl group; R 6 and R 7 , each independently represent a hydrogen atom, an alkyl or alkoxy group or an -alkyl-phenyl group, and R 8 represents a hydrogen atom, an alkyl group or a group of formula —B-Het, where B can be absent or can represent a bond, an oxygen atom or a —CO— or —SO 2 —(CH 2 ) n group wherein n is 0, 1 or 2 and where Het represents a heteroaryl or a heterocycloalkyl optionally substituted with 1 to 3 groups selected from the alkyl, —SO 2 -alkyl and —COOR 5 groups, or a pharmaceutically acceptable salt thereof.