Patent ID: 8193340

Claim:
A preparation method of a porous hyaluronic acid sponge comprising the steps of: dissolving hyaluronic acid in an aqueous sodium hydroxide solution; adding an epoxy-based crosslinking agent to the aqueous sodium hydroxide solution in which hyaluronic acid is dissolved and homogenizing the hyaluronic acid solution; hydrogelating the homogenized hyaluronic acid solution; washing the hydrogelated hyaluronic acid hydrogel with ultrapure water to remove at least excess crosslinking agent; swelling the washed hyaluronic acid hydrogel solely with ultrapure water for 1 to 7 days to attain porosity; and freeze-drying the hyaluronic acid hydrogel to obtain a porous hyaluronic acid sponge, the sponge including a pore size of 30 μm to 500 μm as a scaffold for delivering cells, the cells selected from the group consisting of chondrocytes, stem cells, neurocytes, brain cells, myocytes, sensory cells and blood cells.