Patent ID: 7514579

Claim:
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, where: Ar is aryl or heteroaryl, each of which may be unsubstituted or substituted with a substituent selected from the group consisting of F, Cl, Br, I, alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n -cycloalkyl, Z n -heterocycloalkyl, Z n -OR 1 , Z n -NO 2 , Z n -CN, Z n -CO 2 R 1 , Z n -(C═O)R 1 , Z n -O(C═O)R 1 , Z n -O-alkyl, Z n -OAr, Z n -SH, Z n -SR 1 , Z n -SOR 1 , Z n -SO 2 R 1 , Z n -S-Ar, Z n -SOAr, Z n -SO 2 Ar, Z n -Ar, Z n -heteroaryl, Z n -(C═O)NR 1 R 2 , Z n -NR 1 (C═O)R 1 , Z n -SO 2 NR 1 R 2 , PO 3 H 2 , and SO 3 H 2 ; W is H, Z n -F, Z n -Cl, Z n -Br, Z n -I, Z n -CF 3 , Z n -NO 2 , Z n -OR 1 , Z n -NR 1 R 2 , Z n -COOR 1 , Z n -SR 1 , Z n -(C═O)R 1 , Z n -O(C═O)R 1 , Z n -NR 1 (C═O)R 1 , Z n -(C═O)NR 1 , alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n -cycloalkyl, Z n -heterocycloalkyl, Z n -Ar or Z n -heteroaryl, wherein said alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n , -cycloalkyl, Z n -heterocycloalkyl, Z n -Ar or Z n -heteroaryl may be substituted or unsubstituted; X is Z n , Z n -O, Z n -S, Z n -NR 1 , Z n -NR 1 (C═O), Z n -C═O, Z n -OC(═O), or Z n -C(═O)O; R 1 and R 2 are independently H, an amine protecting group, an alcohol protecting group, an acid protecting group, a sulfur protecting group, alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n -cycloalkyl, Z n -heterocycloalkyl, Z n -Ar or Z n -heteroaryl, wherein said alkyl, allyl, alkenyl, alkynyl, heteroalkyl, heteroallyl, heteroalkenyl, heteroalkynyl, alkoxy, heteroalkoxy, Z n -cycloalkyl, Z n -heterocycloalkyl, Z n -Ar or Z n -heteroaryl may be substituted or unsubstituted, or R 1 together with R 2 and N forms a saturated or partially unsaturated heterocycle ring having 1 or more heteroatoms in said ring, wherein said heterocycle may be substituted or unsubstituted and wherein said heterocycle may be fused to an aromatic ring; Z is an alkylene having at least 1 carbon, or an alkenylene or alkynylene each having at least 2 carbons, wherein said alkylene, alkenylene, or alkynylene may be substituted or unsubstituted; and n is zero or any integer.