Patent ID: 8100871

Claim:
A human implantable liquid therapeutic substance delivery system comprising: a delivery device including: a housing defining a discharge outlet; a reservoir maintained by the housing for containing the therapeutic substance; an access port assembly fluidly connected to the discharge outlet via a fluid pathway, wherein the access port assembly includes an access port passage wall across which an access port septum is disposed; a refill port assembly apart from the access port assembly and fluidly connected to the reservoir, wherein the refill port assembly includes a refill port passage wall across which a refill port septum is disposed; wherein the access port septum and the refill port septum each provide a resealable barrier between an exterior of the housing and an interior of the housing; and a flow restrictor mechanism fluidly connected between the discharge outlet and the access port assembly, and fluidly connected between the discharge outlet and the refill port assembly, so as to establish, relative to the discharge outlet, an outflow fluid flow direction and an inflow fluid flow direction, the flow restriction mechanism configured to have flow restriction characteristics in the outflow direction that differ from flow restriction characteristics in the inflow direction.