Patent ID: 8481558

Claim:
A compound of formula (XIV): wherein: R 1 is: O(Ra) wherein Ra is H, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyl, (C i -C 6 )alkanoyloxy, (C 6 -C 10 )aryl or (C 6 -C 10 )heteroaryl; or N(Rb)(Rc) wherein each Rb and Rc is independently H or (C 1 -C 6 )alkyl; R 2 is: O(Ra) wherein Ra is H, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyl, (C 1 -C 6 )alkanoyloxy, (C 6 -C 10 )aryl or (C 6 -C 10 )heteroaryl; or N(Rb)(Rc) wherein each Rb and Rc is independently H or (C 1 -C 6 )alkyl; R 3 is H, C(═O) or C(═S); R 4 is: H, C(═O), C(═S), O(Ra), or N(Rb)(Rc) wherein each Ra is H, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyloxy, (C 1 -C 6 )alkanoyl, (C 6 -C 10 )aryl or (C 6 -C 10 )heteroaryl, and each Rb and Rc is independently H or (C 1 -C 6 )alkyl; and n is an integer between 1 and 6, inclusive; wherein any (C 6 -C 10 )aryl, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyloxy, (C 6 -C 10 )heteroaryl or (C 1 -C 6 )alkanoyl or the benzo ring in formula (XIV) is optionally substituted with at least one substituent selected from the group consisting of halo, cyano, nitro, trifluoromethyl, trifluoromethoxy, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkanoyl, (C 1 -C 6 )alkanoyloxy, (C 1 -C 6 )alkoxycarbonyl, methoxydioxy, hydroxy, C(═O), sulfino (SO 2 H), sulfo (SO 3 H), and N(Rb)(Rc); or a pharmaceutically acceptable salt thereof.