Patent ID: 8765773

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt thereof; wherein: each occurrence of R 1 is independently hydrogen, chloro, fluoro, —O—C 1-4 alkyl, cyano, hydroxy, C 1-4 alkyl, or C 1-4 fluoroalkyl; one of R 2a and R 2b is R 1 , and the other is —C(O)—NH—OH; X is N—R b ; R 1d is taken together with R 1b to form a double bond; R 1c is hydrogen, fluoro, bromo, —CH 2 —OR 4aa , —CH 2 N(R 4aa ) 2 , or C 1-4 alkyl; R b is hydrogen, C 1-6 alkyl, benzyl, or phenyl; or R b is taken together with R 1b to form a double bond; when X is C(R 1c )(R 1d ), R 1b is taken together with R 1d to form a double bond; and when X is N—R b , R 1b is taken together with R b to form a double bond, or is taken together with R a to form a double bond, or is taken together with R 1a to form C═O; R 1a is hydrogen, fluoro, C 1-4 alkyl, C 1-4 fluoroalkyl, or G 1 ; or when X is N—R b , R 1a can be taken together with R 1b to form C═O; R a is hydrogen, C 1-4 alkyl, or G; or when X is N—R b , R 1b can be taken together with R a to form a double bond; G is hydrogen, —R 3 , -L 1 -R 3 , or -L 2 -V 1 —R 3 ; G 1 is —NH 2 , —R 3 , -L 1 -R 3 , —V 2 —R 3 , -L 1 -V 2 —R 3 , or —V 2 -L 1 -R 3 ; V 1 is —O—, —N(R 4a )—, —S—, —N(R 4a )—C(O)—, —C(O)—N(R 4a )—, —SO 2 —N(R 4a )—, —N(R 4a )—SO 2 —, —C(O)—, —SO 2 —, or —N(R 4a )—C(O)—N(R 4a )—; V 2 is —O—, —N(R 4a )—, —C(O)—N(R 4a )—, —N(R 4a )—C(O)—N(R 4a )—, or —N(R 4a )—C(O)—O—; L 1 is an unsubstituted or substituted C 1-4 alkylene chain; L 2 is an unsubstituted or substituted C 2-4 alkylene chain; each occurrence of R 4aa is independently hydrogen or C 1-4 alkyl; R 3 is unsubstituted or substituted C 1-6 aliphatic, unsubstituted or substituted 3-10-membered cycloaliphatic, unsubstituted or substituted 4-10-membered heterocyclyl having 1-4 heteroatoms independently selected from nitrogen, oxygen, and sulfur, unsubstituted or substituted 6-10-membered aryl, or unsubstituted or substituted 5-10-membered heteroaryl having 1-5 heteroatoms independently selected from nitrogen, oxygen, and sulfur; and each occurrence of R 4a is independently hydrogen, unsubstituted or substituted C 1-4 aliphatic, unsubstituted or substituted 3-10-membered cycloaliphatic, unsubstituted or substituted 4-10-membered heterocyclyl having 1-4 heteroatoms independently selected from nitrogen, oxygen, and sulfur, unsubstituted or substituted 6-10-membered aryl, or unsubstituted or substituted 5-10-membered heteroaryl having 1-5 heteroatoms independently selected from nitrogen, oxygen, and sulfur.