Patent ID: 7470720

Claim:
A pharmaceutical composition comprising a therapeutically effective amount of a compound having the formula: wherein A is a C 1-6 saturated or C 2-6 unsaturated hydrocarbon skeleton, said skeleton being unsubstituted or having between 1 and 10 substituents, inclusive, independently selected from cyano, halo, azido, oxo, and Q 1 ; each Q 1 is independently selected from OR 1 , SR 1 , SO 2 R 1 , OSO 2 R 1 , NR 2 R 1 , NR 2 (CO)R 1 , NR 2 (CO)(CO)R 1 , NR 4 (CO)NR 2 R 1 , NR 2 (CO)OR 1 , (CO)OR 1 , O(CO)R 1 , (CO)NR 2 R 1 , and O(CO)NR 2 R 1 ; each of R 1 , R 2 , R 4 , R 5 , and R 6 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 hydroxyalkyl, C 1-6 aminoalkyl, C 6-10 aryl, C 6-10 haloaryl, C 6-10 hydroxyaryl, C 1-3 alkoxy-C 6 aryl, C 6-10 aryl-C 1-6 alkyl, C 1-6 alkyl-C 6-10 aryl, C 6-10 haloaryl-C 1-6 alkyl, C 1-6 alkyl-C 6-10 haloaryl, (C 1-3 alkoxy-C 6 aryl)-C 1-3 alkyl, C 2-9 heterocyclic radical, C 2-9 heterocyclic radical-C 1-6 alkyl, C 2-9 heteroaryl, and C 2-9 heteroaryl-C 1-6 alkyl; each of D and D′ is independently selected from R 3 and OR 3 , wherein R 3 is H, C 1-3 alkyl, or C 1-3 haloalkyl; n is 0 or 1; E is R 5 or OR 5 ; G is O, S, CH 2 , or NR 6 ; each of J and J′ is independently H, C 1-6 alkoxy, or C 1-6 alkyl; or J and J′ taken together are ═CH 2 or —O-(straight or branched C 1-5 alkylene)-O—; Q is C 1-3 alkyl; T is ethylene or ethenylene, optionally substituted with (CO)OR 7 , where R 7 is H or C 1-6 alkyl; each of U and U′ is independently H, C 1-6 alkoxy, or C 1-6 alkyl; or U and U′ taken together are ═CH 2 or —O-(straight or branched C 1-5 alkylene)-O—; X is H or C 1-6 alkoxy; each of Y and Y′ is independently H or C 1-6 alkoxy; or Y and Y′ taken together are ═O, ═CH 2 , or —O-(straight or branched C 1-5 alkylene)-O—; and each of Z and Z′ is independently H or C 1-6 alkoxy; or Z and Z′ taken together are ═O, ═CH 2 or —O-(straight or branched C 1-5 alkylene)-O—; or a pharmaceutically acceptable salt thereof.