Patent ID: 8008501

Claim:
A compound according to structural formula (I): and a salt, hydrate, solvate or N-oxide thereof, wherein: R 1 is an alkyl group optionally substituted with one or more of the same or different R l0 groups; R 2 , R 3 , R 5 , R 6 , R 7 and R 8 are each, independently of one another, seleted from the group consisting of a hydrogen atom, —OR d , —SR d , (C1-C3) haloalkyloxy, (C1-C3) perhaloalkyloxy, —NR c -aryl, —NR c -heteroaryl, halogen, (C1-C3) haloalkyl, (C1-C3) perhaloalkyl, —CF 3 , —CH 2 CF 3 , —CF 2 CF 3 , (C1-C6) alkyl optionally substituted with one or more of the same or different R 10 groups, (C5-C10) aryl optionally substituted with one or more of the same or different R 10 groups, phenyl optionally substituted with one or more of the same or different R 10 groups, and 5-10 membered heteroaryl optionally substituted with one or more of the same or different R 10 groups; R 9 is selected from the group consisting of (C1-C3) haloalkyl, (C1-C3) perhaloalkyl, —CF 3 , —CH 2 CF 3 , —CF 2 CF 3 , (C1-C6) alkyl optionally substituted with one or more of the same or different R 10 groups, (C5-C10) aryl optionally substituted with one or more of the same or different R 10 groups, phenyl optionally substituted with one or more of the same or different R 10 groups; R 10 is selected from the group consisting of R a , R b , R a substituted with one or more of the same or different R a or R b , —OR a substituted with one or more of the same or different R a or R b , —(CH 2 ) m —R b , —(CHR a ) m —R b , —O—(CH 2 ) m —R b ,—S—(CH 2 ) m —R b , and-O—(CHR a ) m —R b ; each R a is independently selected from the group consisting of hydrogen, (C1-C6) alkyl, (C3-C8) cycloalkyl, cyclohexyl, (C4-C11) cycloalkylalkyl, (C5-C10) aryl, phenyl, (C6-C16) arylalkyl, benzyl; each R b is a suitable group independently selected from the group consisting of —OR d , (C1-C3) haloalkyloxy, halogen, and —CF 3 , each R c is independently a protecting group, R a or R a optionally substituted with one or more of the same or different R a or suitable R b groups; each R d is independently a protecting group, R a or R a optionally substituted with one or more of the same or different R a or suitable R b groups; each m is independently an integer from 1 to 3; A is NH or CO; and B is CO, NH or O, provided that one of A or B is C(O).