Patent ID: 8260399

Claim:
A method of injecting a therapeutic agent into target intramyocardial tissue during a magnetic resonance imaging (MRI)-guided interventional procedure using an intramyocardial catheter having an injection needle, comprising: intraluminally inserting a distal end of the intramyocardial catheter into a heart of a patient during the MRI-guided procedure, wherein the intramyocardial catheter comprises a deflectable tip section having a predetermined length and a pull wire within the deflectable tip section, and wherein the pull wire is configured as a catheter antenna; obtaining a first RF output signal from the catheter antenna in the heart of the patient; tuning the first RF output signal from the catheter antenna using a first matching-tuning circuit to track the catheter antenna during the MRI-guided interventional procedure; tracking the catheter antenna in the heart of the patient during the MRI-guided interventional procedure; deflecting the deflectable tip section of the catheter in the heart to steer a distal end of the deflectable tip section toward a target intramyocardial location using the pull wire based on MRI images generated from the tracked catheter antenna; advancing an injection needle from the deflectable tip section of the catheter toward the target intramyocardial location, wherein the injection needle comprises an injection needle antenna; obtaining a second RF output signal from the injection needle antenna in the heart of the patient; tuning the second RF output signal from the injection needle antenna using a second matching-tuning circuit, different from the first matching-tuning circuit, to track the injection needle antenna during the MRI-guided interventional procedure; tracking the injection needle antenna in the heart of the patient during the MRI-guided interventional procedure; injecting a therapeutic agent from the injection needle into tissue at the target intramyocardial location, wherein positions and locations of the catheter antenna and the injection needle antenna are separately and independently tracked to visualize the deflectable tip section of the catheter in the heart of the patient separately and independently of the injection needle on MRI images generated during the MRI-guided interventional procedure.