Patent ID: 8691267

Claim:
A patch, comprising: a backing layer; and an adhesive layer disposed on the backing layer, the adhesive layer comprising pergolide mesylate and an adhesive base agent comprising a styrene-isoprene-styrene block copolymer, 2-ethylhexyl acrylate-vinyl acetate copolymer, wherein the weight ratio of the content of the styrene-isoprene-styrene block copolymer to 2-ethylhexyl acrylate-vinyl acetate copolymer is from 1:1 to 9:1, and a basic nitrogen-containing polymer comprising a basic nitrogen and having no adhesion properties at normal temperature, the basic nitrogen-containing polymer being selected from the group consisting of methyl methacrylate-butyl methacrylate-dimethylaminoethyl methacrylate terpolymer, and polyvinyl acetal diethylamino acetate, wherein the patch is configured to have a maximum skin permeation rate of 1.5 μg/cm 2 /hr and to have improved adhesion, cohesion or stability.