Patent ID: 8062879

Claim:
An isolated polynucleotide comprising or consisting of a nucleic acid sequence selected from the group consisting of: (a) SEQ ID NO:2; (b) a nucleic acid sequence that is a degenerate variant of SEQ ID NO:2; (c) a nucleic acid sequence at least 95% identical to SEQ ID NO:2 wherein said nucleic acid sequence encodes a polypeptide having orotate-phosphoribosyl transferase activity; (d) a nucleic acid sequence that encodes a polypeptide having the amino acid sequence of SEQ ID NO:3; (e) a nucleic acid sequence that encodes a polypeptide at least 95% identical to SEQ ID NO:3 wherein said nucleic acid sequence encodes a polypeptide having orotate-phosphoribosyl transferase activity; (f) a nucleic acid sequence that hybridizes under stringent conditions to SEQ ID NO:2 wherein said nucleic acid sequence encodes a polypeptide having orotate-phosphoribosyl transferase activity; and (g) a nucleic acid sequence comprising a fragment of any one of (a)-(f) wherein said fragment encodes a polypeptide having orotate-phosphoribosyl transferase activity.