Patent ID: 8222285

Claim:
A compound having the structure or stereoisomers or a pharmaceutically acceptable salt thereof; wherein R 1 is selected from alkyl optionally substituted with —OH or alkoxy, aryl, arylalkyl, or heteroaryl optionally substituted with F or Cl; R 2 is selected from alkyl, aryl optionally substituted with —S(O) 2 (alkyl), arylalkyl, or heteroaryl optionally substituted with —S(O) 2 (alkyl) or —C(O)(heterocyclo); Z is selected from , O, S, S(O), or S(O) 2 ; R 4 is selected from H or alkyl; R 6 and R 7 are independently selected from H, halogen, or alkyl; R 8 is selected from aryl or heteroaryl; wherein R 8 is substituted with at least one substituent selected from where R f and R g are independently selected from H, alkyl and aryl; R h is alkyl or aryl; and R i and R j are independently selected from H, alkyl and aryl; provided that at least one of R i and R j is other than H; and n is 0, 1, 2, or 3.