Patent ID: 7094346

Claim:
A filtration cassette comprising: one or more filter membranes, each having at least one port for filtrate flow and at least one port for retentate flow; one or more filtrate flow screens, each having at least one port for filtrate flow and at least one port for retentate flow and further having one or more channels in proximity to and at least partially surrounding the port for retentate flow, wherein the one or more channels on the filtrate flow screen permit introduction of a sealant such that the port for retentate flow on the filtrate flow screen may be selectively blocked; and one or more retentate flow screens, each having at least one port for filtrate flow and at least one port for retentate flow and further having one or more channels in proximity to and at least partially surrounding the port for filtrate flow, wherein the one or more channels on the retentate flow screen permit introduction of a sealant such that the port for filtrate flow on the retentate flow screen may be selectively blocked; wherein the one or more filter membranes, filtrate flow screens and retentate flow screens are assembled and encapsulated about the periphery thereof by sealant; and wherein the sealant contemporaneously seals the respective channels of the one or more filtrate flow screens and retentate flow screens to selectively block one or more ports in proximity thereto.