Patent ID: 8404728

Claim:
A composition comprising a compound of Formula (IIA): or a pharmaceutically acceptable salt or derivative thereof, wherein: R 1 is chosen from NH 2 , aryl, and heteroaryl; R 2 is chosen from NR 2a R 2b ; R 2a and R 2b are chosen from (CH 2 ) m NH 2 ; m is an integer from 4 to 12; R 3 is chosen from thiol, imidazole, sulfonamide, COOH, and CONHOH; R 4 and R 5 are independently chosen from aryl and heteroaryl; R 6 is chosen from H, OH, CH 2 OH, NH 2 , aryl and heteroaryl; U and X are independently (CH 2 ) m1 V(CH 2 ) m2 ; V is chosen from C, C(OH), 0, S, and NH, or is absent; m1 is an integer from 0 to 2; m2 is an integer from 0 to 2; W is chosen from 0 and S, or is absent; Y is chosen from CO(CH 2 ) m3 , (CH 2 ) m3 , and CONH(CH 2 ) m3 ; m3 is an integer from 1 to 10; and all non-hydrogen atoms in the pyrrole ring can be substituted by N, S, or O provided the substitution maintain aromaticity.