Patent ID: 7468373

Claim:
A compound having the structure of Formula I or a pharmaceutically acceptable salt thereof, wherein (a) R 2 is selected from, optionally substituted aryl, (b) R 3 is from one to four groups independently selected from the group consisting of: hydrogen, halo, C 1-8 straight or branched chain alkyl, arylalkyl, C 3-7 cycloalkyl, C 1-8 alkoxy, cyano, C 1-4 carboalkoxy, trifluoromethyl, C 1-8 alkylsulfonyl, halogen, nitro, hydroxy, trifluoromethoxy, C 1-8 carboxylate, aryl and —NR 11 R 12 , wherein; R 11 and R 12 are independently selected from H, C 1-8 straight or branched chain alkyl, arylalkyl, C 3-7 cycloalkyl, carboxyalkyl and aryl, and, -NR 13 COR 14 , wherein; R 13 is selected from hydrogen or alkyl and R 14 is selected from hydrogen, alkyl, substituted alkyl, C 1-3 alkoxyl, carboxyalkyl, aryl, arylalkyl, R 15 R 16 N (CH 2 ) p —, or R 15 R 16 NCO(CH 2 ) p —, Wherein; R 15 and R 16 are independently selected from H, OH, alkyl, and alkoxy, and p is an integer from 1-6, wherein; the alkyl group may be substituted with carboxyl, alkyl, aryl, substituted aryl hydroxamic acid, sulfonamide, sulfonyl, hydroxy, thiol, alkoxy or arylalkyl; (c) R 4 is amino, (d) X is C═O.