Patent ID: 8906367

Claim:
An isolated antibody or antigen-binding fragment thereof which binds to beta amyloid and comprises a heavy chain variable region (VH) and a light chain variable region (VL), wherein the VH comprises a first complementarity determining region (VHCDR1) with the amino acid sequence SEQ ID NO:20, a VHCDR2 with the amino acid sequence SEQ ID NO:21, and a VHCDR3 with the amino acid sequences SEQ ID NO:22, and wherein the VL comprises a VHCDR1 with the amino acid sequence SEQ ID NO:23, a VHCDR2 with the amino acid sequence SEQ ID NO:24, and a VHCDR3 with the amino acid sequence SEQ ID NO:25, wherein the antibody or fragment thereof further comprises a human IgG1constant region or fragment thereof.