Patent ID: 6949345

Claim:
A kit for serological diagnosis of mycobacterial infections comprising at least: a) a reactant consisting of: (i) an HBHA protein purified from a preparation of mycobacterium cell walls, or a fragment thereof, determined by epitope mapping; or (ii) a fragment comprised in the last 30 to 50 amino acids in a C-terminal portion of said HBHA protein or in the last 50 C-terminal amino acids of SEQ ID NO. 19; or (iii) a recombinant peptide sequence which is obtainable by expression in a host cell of a polynucleotide sequence of SEQ ID NO. 19, and wherein said recombinant peptide sequence is an HBHA mycobacterial antigen enabling the adhesion of mycobacteria to the sulphated glucides of epithelial cells; said reactant being coupled to or adsorbed on a support; b) an anti-antibody antibody, modified such that a detection signal can be coupled thereto.