Patent ID: 6987187

Claim:
A process for producing a compound of the formula (II): wherein ring A represents a 5 to 9 membered alicyclic group, which may contain at least one of O, S, SO, SO 2 and/or NR 1 and may be substituted with at least one alkyl; R 1 is hydrogen, alkyl, esterified carboxy, carbamoyl or acyl; R is optionally substituted aryl or optionally substituted aromatic heterocyclic group; and Hal is a halogen, comprising Step 1, wherein a compound of the formula (v): wherein R 10 is optionally substituted aryl, optionally substituted aromatic heterocyclic group, optionally substituted alkyl, or optionally substituted cycloalkyl; and ring A is as defined above, is reacted with a halogenating agent in acetonitrile in the presence of dimethylformamide and then hydrolyzed to obtain a compound of the formula (IV): wherein ring A is as defined above, and Hal is a halogen, Step 2, wherein the resultant compound (IV) is reacted with a compound of the formula R—COR 11 , wherein R is optionally substituted aryl or optionally substituted aromatic heterocyclic group, and R 11 is hydroxy or halogen, in acetone in the presence of an organic base and optionally further a halogenating agent to obtain a compound of the formula (III): wherein ring A, Hal and R are as defined above, and Step 3, wherein the obtained compound of the formula (III) is reacted with a halogenating agent in acetonitrile in the presence of an organic base and then aminated.