Patent ID: 8227570

Claim:
An isolated or purified peptide-type compound or a pharmaceutically acceptable salt thereof of the amino acid sequence of SEQ ID NO: 2, wherein one or more amino acid residues in position 5 to 28 of SEQ ID NO: 2 may be deleted, and/or wherein at least one amino acid residue in position 5 to 28 of SEQ ID NO: 2 may be substituted, wherein the second or third amino acid residue from the amino-terminal is a modified amino acid in which: (1) one saturated or unsaturated alkyl chain containing 1 to 35 carbon atoms is introduced at the α carbon atom of the amino acid by an ester, ether, thioether, thioester, amide, carbamide, thiocarbamide or disulfide linkage; (2) one saturated or unsaturated alkyl chain containing 1 to 35 carbon atoms is introduced at the α carbon atom of the amino acid by an alkylene group containing 1 to 10 carbon atoms and by an ester, ether, thioether, thioester, amide, carbamide, thiocarbamide or disulfide linkage; or (3) one saturated or unsaturated alkyl chain containing 1 to 35 carbon atoms is introduced at the α carbon atom of the amino acid, and wherein said peptide-type compound has an activity of increasing intracellular calcium ion concentration.