Patent ID: 7943603

Claim:
A method of treating atherosclerosis, said method comprising increasing levels of a sex steroid precursor selected from the group consisting of dehydroepiandrosterone, dehydroepiandrosterone sulfate, androst-5-ene-3b,17b-diol and 4-androsten-3,17-dione in a patient in need of said treatment, and further comprising administering to said patient a therapeutically effective amount of a selective estrogen receptor modulator having the following molecular structure or pharmaceutically acceptable salt thereof: wherein n is 2 and wherein R 1 and R 2 are independently selected from the group consisting of hydroxy and acyloxy, as part of a combination therapy wherein said sex steroid precursor and said selective estrogen receptor modulator are administered in synergistically effective amounts for treatment of atherosclerosis, provided that the selective estrogen receptor modulator is not: