Patent ID: 7626040

Claim:
A compound of formula II: wherein: n is 1, 2, or 3; p is 0, 1, 2, 3, or 4; R 3 and R 4 are independently selected from the group consisting of hydrogen, hydroxy, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic, provided that only 1 of R 3 or R 4 is hydroxy; or R 3 and R 4 together with the nitrogen atom pendent thereto join to form a heterocyclic or substituted heterocyclic; R 10 is selected from the group consisting of hydrogen, alkyl optionally substituted with a substituent selected from the group consisting of hydroxy, alkoxy, substituted alkoxy, amino, substituted amino, acylamino, halo, nitrogen-containing heterocycle, substituted nitrogen-containing heterocycle, nitrogen-containing heteroaryl, and substituted nitrogen-containing heteroaryl; R 11 is selected from the group consisting of cyano, alkyl, alkenyl, alkynyl, —CF 3 , alkoxy, halo, and hydroxy, provided that when p is 2-4, then each R 11 may be the same or different; R 12 is alkyl; R 13 is hydrogen or alkyl, R 14 is selected from the group consisting of hydrogen, halo, and alkyl; or R 4 and R 10 , together with the atoms bound thereto, form a heterocyclic or substituted heterocyclic group; A 2 is selected from the group consisting of aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, cycloalkyl, and substituted cycloalkyl; or a pharmaceutically acceptable salt or ester thereof.