Patent ID: 8263170

Claim:
A method for immobilizing an anti-thrombogenic material onto a coating deposited on a surface of an implantable medical device, the method comprising: preparing a base coat mixture for application to the surface of the medical device, the surface of the implantable medical device optionally coated with a primer layer; applying the base coat mixture to the surface of the medical device; polymerizing the base coat mixture to form a base coat layer on the medical device, the base coat layer comprising chemically functional groups; performing a reaction between the chemically functional groups of the base coat layer and excess amine-terminated material; rinsing the base coat layer with water; and performing a reaction between the anti-thrombogenic material and amine-terminated material on the surface of the medical device; wherein the amine-terminated material is amine-terminated hyaluronic acid or amine-terminated polyvinyl pyrrolidone.