Patent ID: RE38963

Claim:
A derivative of pyrazoline of formula (I) wherein R 1 represents hydrogen, a methyl, fluoromethyl, difluormethyl, trifluoromethyl, carboxylic acid, lower carboxylate of 1 to 4 carbon atoms, carboxamide or cyano group; R 2 represents a hydrogen or methyl group; R 3 , R 4 , R 7 and R 8 , are the same or different, represent hydrogen, chlorine, fluorine, methyl, trifluoromethyl or methoxy group; R 5 represents hydrogen, chlorine, fluorine, methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylsulphonyl, aminosulphonyl or acetoaminosulphonyl group; R 6 represents hydrogen, chlorine, fluroine, methyl, or trifluromethyl, methoxy, trifluoromethoxy, methylsulphonyl, aminosulphonyl or acetylaminosulphonyl group, with the provisio that one of R 5 or R 6 represents hydrogen, chlorine, fluorine, methyl, trifluoromethyl, methoxy, or trifluoromethoxy and the other of R 5 or R 6 represents a methylsulfonyl, aminosulphonyl, or a acetylaminosulphonyl group; with the provision that when R 1 represents a methyl group then R 2 represents a hydrogen atom or a methyl group; R 3 and R 8 , are the same or different, and represent hydrogen, chlorine, fluorine, methyl or trifluoromethyl group; R 4 represents hydrogen, fluorine, methyl, trifluoromethyl or methoxy group; R 5 represents fluorine, triflouromethyl, trifluoromethoxy, and R 6 methylsulfonyl or amino sulphonyl group; R 6 represents hydrogen, chlorine, fluorine, methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylsulphonyl or aminosulphonyl group, with the proviso that one of R 5 or R 6 represents hydrogen, chlorine, fluorine, methyl, trifluoromethyl, and the other of R 5 or R 6 represent methylsulphonyl or aminosulphonyl; and R 7 represents hydrogen, chlorine, fluorine, methyl, trifluoromethyl or methoxy group; or a physiologically acceptable salt thereof.