Patent ID: 7615643

Claim:
A compound of formula (I): wherein: R 1 is selected from H, halo, alkyl, haloalkyl, —OR 7 , —CN, —C(O)NR 7 R 8 , —S(O) 2 R 7 , —R 5 —S(O) 2 R 7 , —NR 7 R 8 , —NR 7 C(O)R 8 , Ph, and Het 1 ; Ph is phenyl optionally substituted 1 or 2 times with halo, alkyl, haloalkyl, —OR 7 , —CN, —S(O) 2 R 7 or —NR 7 R 8 ; Het 1 is a 5-6 membered heteroaryl having 1, 2 or 3 heteroatoms selected from N, O and S, optionally substituted 1 or 2 times with a substituent selected from halo, alkyl, haloalkyl, —OR 7 , —CN, —S(O) 2 R 7 , —NR 7 R 8 , Het 2 , —R 5 -Het 2 , and NR 7 -Het 2 ; Het 2 is a 5-6 membered heterocycle having 1 or 2 heteroatoms selected from N, O and S, optionally substituted 1 or 2 times with a substituent selected from alkyl, —OR 7 , —NR 7 R 8 , —C(O)NR 7 R 8 , —S(O) 2 R 7 , and oxo; R 2 is selected from H, halo, alkyl, haloalkyl, —OR 7 , —CN, —C(O)NR 7 R 8 , —S(O) 2 R 7 , —R 5 —S(O) 2 R 7 , —S(O) 2 NR 7 R 8 , —R 5 —S(O) 2 NR 7 R 8 , —NR 7 R 8 , and —NR 7 C(O)R 8 ; R 3 is H, alkyl or haloalkyl; Z 1 , Z 2 and Z 3 are each the same or different and are independently C, CH or N, wherein at least one of Z 1 , Z 2 and Z 3 is C or CH; d is 0, 1 or 2; each R 4 is the same or different and is independently halo, alkyl or haloalkyl; Y 1 is —O— or —N(R 7 )—; a is 0 or 1; each R 5 is the same or different and is independently C 1-3 alkylene; Ring A is a 5-6 membered heterocycle having 1 or 2 heteroatoms selected from N, O and S; b is 0, 1 or 2; each R 6 is the same or different and is independently selected from halo, alkyl, haloalkyl, alkenyl, —CN, —R 5 —CN, —CO 2 R 7 , —R 5 —CO 2 R 7 , —C(O)NR 7 R 8 , —R 5 —C(O)NR 7 R 8 , —OR 7 , —R 5 —OR 7 , —S(O) 2 R 7 , —R 5 —S(O) 2 R 7 , —S(O) 2 NR 7 R 8 , —R 5 —S(O) 2 NR 7 R 8 , —NR 7 R 8 , —R 5 —NR 7 R 8 , —NR 7 C(O)R 8 , —NR 7 S(O) 2 R 8 , —NR 7 C(O)NR 7 R 8 , —NR 7 C(O) 2 R 8 and oxo; each R 7 and each R 8 are the same or different and are each independently selected from H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, cycloalkyl and cycloalkenyl; or a pharmaceutically acceptable salt thereof.