Patent ID: 8258177

Claim:
A method for treating a condition selected from the group consisting of diabetes, cardiovascular diseases, Metabolic X Syndrome, hypercholesterolemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia, dyslipidemia, atherosclerosis, and obesity comprising administering to a patient in need of such treatment an effective amount of a compound of Formula (I): wherein X is selected from a covalent bond, S, and O; Y is S or O; Z is O or CH 2 , provided when Y is O, then Z is O; R 1 and R 2 are independently selected from H, C 1-3 alkyl, C 1-3 alkoxy, halo, and NR a R b wherein R a and R b are independently H or C 1-3 alkyl; R 3 and R 4 are independently selected from H, halo, cyano, C 1-5 alkyl, hydroxy, C 2-4 acyl, C 1-4 alkoxy, and NR c R d wherein R c and R d are independently H or C 1-3 alkyl, provided that R 3 and R 4 are not both H; R 5 and R 6 are independently selected from halo, phenyl, C 1-9 alkyl, C 1-8 alkoxy, C 2-9 alkenyl, C 2-9 alkenyloxy, C 3-7 cycloalkyl, C 3-7 cycloalkoxy, C 3-7 cycloalkyl-C 1-7 alkyl, C 3-7 cycloalkyl-C 1-7 alkoxy, C 3-7 cycloalkyloxy-C 1-6 alkyl, and C 3-7 cycloalkyloxy-C 1-7 alkoxy, or R 5 and R 6 together form C 1-9 alkylidenyl or C 3-9 alkenylidenyl; or R 5 , R 6 and the carbon atom to which they are attached together form C 3-7 cycloalkyl or 5- or 6-membered heterocyclyl; n is 0, 1 or 2; and m is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.