Patent ID: 8552191

Claim:
A process for making a lactam compound of Formula I the process comprising reacting a compound of the Formula 27a-sulfonate with zinc in the presence of acetic acid, thereby forming the lactam of Formula I, wherein: R 1 is selected from linear, branched, or cyclic alkyl having up to 6 carbon atoms, phenyl, 2-methoxy-ethyl, 2-(dimethylamino)ethyl, (L)-menthyl, (D)-menthyl, dimethylamide, (R)-benzyl-oxazolidinonamide, (S)-benzyl-oxazolidinonamide, isobornyl, norbornyl, cis-pinan-2-yl, isopinocampheyl, adamantylmethyl, 2-adamantyl, 1-adamantyl, and (−)-8-phenylmenthyl; and R 5 is selected from methyl, alkyl, benzyl, and p-toluoyl.