Patent ID: 8790295

Claim:
A system comprising: a catheter having a proximal end, a distal region including an opening, a lumen extending from the proximal end to the opening, and a one-way valve, the valve being disposed in proximity to the opening and configured to allow fluid to exit the lumen through the opening; an infusion device having a housing, and a reservoir, an infusion mechanism, electronics and a pressure sensor disposed within the housing, wherein the reservoir is configured to store therapeutic fluid, wherein the infusion mechanism is configured to cause fluid from the reservoir to be infused through the lumen of the catheter when the catheter is operably coupled to the infusion device, wherein the pressure sensor is configured and positioned such that the pressure sensor is capable of detecting pressure changes in the lumen of the catheter; the pressure sensor being operably coupled to the electronics, wherein the electronics are configured to control the rate that the therapeutic fluid is delivered from the reservoir to the lumen of the catheter and are configured to modify the rate of delivery based on intralumenal pressure detected by the pressure sensor, wherein the rate of delivery is increased if the internal pressure of the catheter is increase, and the rate of delivery is decreased if the internal pressure of the catheter is decreased.