Patent ID: 7820630

Claim:
A method for treating diabetes or Syndrome X, or associated symptoms or complications thereof in a subject, comprising (a) administering to said subject a jointly effective amount of a compound of formula (I) wherein R 1 is H, C 1-4 alkyl, or R 4 R 5 N—(CO)—; each of R 4 and R 5 is independently C 1-5 alkyl; R 2 is H, F, Cl or C 1-4 alkyl; R 3 is H or C 1-4 alkyl, provided that where R 3 is C 1-4 alkyl, then R 2 is H; Q is —C(O)—, or —(CH 2 ) n — where n=0, 1, or 2; P=H, C 1-7 acyl, or (C 1-6 alkoxy)carbonyl; Z is substituted or unsubstituted, and is selected from C 3-7 cycloalkyl, phenyl, 5- or 6-membered heterocyclyl having 1 or 2 heteroatoms independently selected from N, O, and S, a biaryl, a 9- or 10-membered fused bicyclyl or fused heterobicyclyl, wherein said fused heterobicyclyl has between 1 and 4 heteroatoms independently selected from N, O, and S; or a pharmaceutically acceptable salt, thereof, (b) administering to said subject a jointly effective amount of a second antidiabetic agent, and (c) administering to said subject a jointly effective amount of a third antidiabetic agent.