Patent ID: 8134001

Claim:
A compound of the formula wherein X is CI, F or Br R is a substituted phenyl or substituted heteroaryl with the substituted phenyl or substituted heteroaryl selected from group consisting of: W is selected from the group consisting of F, CI, Br, I, methyl, ethyl, cyclopropyl, cyano, methoxy, hydroxymethyl, COOMe, ethynyl, CF 3 , vinyl, isopropenyl, 1-propynyl, 3-methyl-1-butynyl, 3,3-dimethyl-1-butynyl, 3-trifluoroethynyl, phenyl, 2-furany, 2-thiophenyl and 4-thiazolyl, Y is hydrogen, F, CI or Me, V is hydrogen, F, CI or methyl, A is selected from the group consisting of O and NH, n=1, 2 or 3, R′ is selected from the group consisting of heterocycle, substituted heterocyle, heteroaryl, substitluted heteroaryl, aryl, substituted aryl, substituted cycloalkyl, and CR 1 R 2 C(═O)NR 3 R 4 wherein R 1 , R 2 are hydrogen or lower alkyl, or may independently link to form a cyclic structure selected from a substituted or unsubstituted cycloalkyl and R 3 , R 4 are independently selected from the group consisting of hydrogen, lower alkyl, aryl, lower alkenyl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, cycloalkyl and substituted cycloalkyl with the proviso that R 3 , R 4 are not both hydrogen, or R 3 /R 4 may independently link to form a cyclic structure selected from a substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl or a substituted or unsubstituted heterocycle and the pharmaceutically acceptable salts and esters thereof.