Patent ID: 7041642

Claim:
A compound of the formula: wherein R 1 is a light-emitting moiety and R 2 is a bombesin-like peptide, fragment, derivative or analog thereof, wherein R 2 is chosen from the group consisting of Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met (SEQ ID NO:2), Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met (SEQ ID NO:3), and Dphe-Gly-Trp-Ala-Val-betaAla-His-Phe-Nle (SEQ ID NO:5), and L is a linker moiety, wherein n is 1 or 0, and (C—X) is selected from the group consisting of C═O, C═S, CH(OH), C═C═O, C═NH, CH 2 , CH(OR), CH(NR), CH(R), CR 3 R 4 , and C(OR 3 )OR 4 where R, R 3 , and R 4 are alkyl moieties or substituted alkyl moieties, and wherein (L) n —R 2 is linked to (C—X) at L or at an amino acid position selected such that the compound exhibits substantial biological activity in the presence of a receptor having affinity for bombesin-like peptides, wherein said compound exhibits substantial biological activity in the presence of a receptor having affinity for bombesin-like peptides.