Patent ID: 7829549

Claim:
A method for treating a subject for a bleeding disorder, the method comprising administering a therapeutically effective amount of a composition comprising a procoagulant amount of a non-anticoagulant sulfated polysaccharide (NASP) selected from the group consisting of: pentosan polysulfate (PPS); and a modified heparin selected from the group consisting of N-acetyl-heparin (NAH), N-acetyl-de-O-sulfated-heparin (NA-de-o-SH), de-N-sulfated-heparin (De-NSH), and de-N-sulfated-acetylated-heparin (De-NSAH), each having a molecular weight in the range of 10,000 Da to 1,000,000 Da; and combinations thereof, to said subject; wherein the NASP is administered at a dosage of about 0.01 mg/kg to about 100 mg/kg, and the bleeding disorder is selected from the group consisting of a chronic or acute bleeding disorder, a congenital coagulation disorder caused by a blood factor deficiency, and an acquired coagulation disorder.