Patent ID: 8071595

Claim:
A compound of Formula (I) or pharmaceutically acceptable salt thereof Wherein: HET is a heterocyclic ring selected from Formulas A1-A26 and A29-42 below and the left most radical is connected to the X group; W is selected from halogen, cyano, nitro, alkoxy, amino, alkylamino, dialkylamino, carboxy, amido, alkylamido, and dialkylamido; X is selected from C 3 -C 8 alkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 4 -C 7 cycloalkylalkyl, optionally substituted heterocycloalkyl, optionally substituted heterocycloalkylalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl and optionally substituted heteroarylalkyl; Y is a bond or a divalent linker group selected from â€”CH 2 â€”, â€”Oâ€”, â€”SO 2 â€”, â€”CH 2 Oâ€”, â€”OCH 2 â€” and â€”CH 2 CH 2 â€” with the rightmost radical of the Y group connected to the Z substituent; Z is optionally substituted heteroaryl; R 1a is selected from C 1 -C 4 alkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 4 -C 7 cycloalkylalkyl and optionally substituted C 4 -C 7 alkoxyalkyl; R 1b is selected from C 1 -C 4 alkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 4 -C 7 cycloalkylalkyl and optionally substituted C 4 -C 7 alkoxyalkyl; Each R 2 is independently selected from C 1 -C 4 alkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 4 -C 7 cycloalkylalkyl and optionally substituted C 4 -C 7 alkoxyalkyl, or two R 2 groups taken together form a 3-6 membered cycloalkyl ring; R 3 and R 4 are independently selected from C 1 -C 4 alkyl, CF 3 , optionally substituted C 3 -C 6 cycloalkyl, or R 3 and R 4 taken together form a 3-6 membered cycloalkyl ring; R 5 is selected from C 1 -C 4 alkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 4 -C 7 cycloalkylalkyl and optionally substituted C 4 -C 7 alkoxyalkyl; R 6 is selected from hydrogen, C 1 -C 6 alkyl, optionally substituted C 3 -C 6 cycloalkyl and optionally substituted C 3 -C 6 cycloalkylalkyl; R 7 is selected from hydrogen, C 1 -C 4 alkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 4 -C 7 cycloalkylalkyl and optionally substituted C 4 -C 7 alkoxyalkyl; n is independently selected from 1 and 2.