Patent ID: 8232269

Claim:
A compound of Formula (I): wherein, R 1 and R 2 each independently represent H, halogen, CF 3 , C 1-3 alkyl or C 1-3 alkoxy; R 3 represents C 1-6 alkyl, C 3-6 cycloalkyl, phenyl which is optionally substituted by one or more substituents each independently selected from R a ; or Het which is optionally substituted by one or more substituents each independently selected from OH, oxo, or C 1-4 alkyl; R a represents halogen, CF 3 , or CN; Het represents a 5- or 6- membered, saturated, partially saturated, or aromatic, heterocyclic ring comprising (a) from 1 to 4 nitrogen atoms, or (b) 1 or 2 nitrogen atoms and 1 oxygen atom or 1 sulphur atom, or (c) 1 oxygen atom or 1 sulphur atom; R 4 represents H or C 1-3 alkyl; R 5 represents Het 2 which is optionally substituted by one or more substituents each independently selected from R d ; where Het 2 represents a 4- to 6-membered, saturated, partially saturated, or aromatic, monocyclic heterocyclic ring, or a 7- to 12-membered saturated, partially saturated, or aromatic, bicyclic heterocyclic ring, comprising (a) from 1 to 4 nitrogen atoms, or (b) 1 or 2 nitrogen atoms and 1 oxygen atom or 1 sulphur atom, or (c) 1 oxygen atom or 1 sulphur atom; and R d represents C 1-4 alkyl, oxo, OH, COC 1-4 alkyl, COOC 1-4 alkyl, SO 2 C 1-4 alkyl, NH 2 , CONHC 1-4 alkyl, or CON(C 1-4 alkyl) 2 ; and R 6 represents C 1-3 alkyl which is optionally substituted by one or more substituents each independently selected from R f ; C 3-5 cycloalkyl which is optionally substituted by one or more halogen; CN or halogen; where R f represents halogen or phenyl; or a pharmaceutically acceptable salt or solvate thereof.