Patent ID: 7604946

Claim:
A cardiac troponin assay method, comprising: measuring the concentration of cardiac troponin I in a body fluid sample obtained from a human subject using an immunoassay for cardiac troponin I on said body fluid sample, wherein said immunoassay uses antibodies comprising (a) a first antibody that specifically binds to uncomplexed cardiac troponin I, wherein said first antibody also specifically binds to cardiac troponin I complexed to troponin T and troponin C; or (b) another first antibody that specifically binds to cardiac troponin I, uncomplexed to either troponin T or troponin C and a second antibody that specifically binds to cardiac troponin I, complexed to troponin T and troponin C; or (c) a combination thereof; and wherein said immunoassay is configured to provide assay results that are within a factor of two for (i) cardiac troponin I, uncomplexed to either troponin T or troponin C, at a concentration between 1 and 15 ng/mL; and (ii) an equivalent concentration of cardiac troponin I in a complex with troponin T and troponin C.