Patent ID: 7312333

Claim:
A compound represented by the formula: or a pharmaceutically acceptable salt thereof, wherein t represents 0 or 1; R 1 is a radical selected from the group consisting of a hydrogen radical, —CH 2 SO 2 NH 2 , —CO 2 CH 3 , —CH 2 CO 2 CH 3 , —CO 2 H, —CH 2 CO 2 H, —CH 2 CH 2 CO 2 H, —CH 2 CH 2 CONH 2 , —CH 2 CONH 2 , —CONH 2 , —CONHCH 3 , —CON(CH 3 ) 2 , —CH 2 CONHCH 3 , —CH 2 CHCON(CH 3 ) 2 , —CH 2 SCH 3 , —CH 2 S(O)CH 3 , —CH 2 S(O) 2 CH 3 , alkyl, alkenyl, alkynyl, aralkyl, heteroaralkyl, aminoalkyl, hydroxyalkyl, cyanoalkyl, and cycloalkyl or a radical of a side chain of an amino acid selected from the group consisting of asparagine, S-methyl cysteine, the corresponding sulfoxide and sulfone derivatives of S-methyl cysteine, leucine, isoleucine, allo-isoleucine, tert-leucine, alanine, phenylalanine, ornithine, histidine, norleucine, glutamine, valine, threonine, allo-threonine, serine, aspartic acid and beta-cyano alanine; R 3 is a radical selected from the group consisting of a hydrogen radical, alkyl, alkenyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heteroaryl, heterocycloalkylalkyl, aryl, aralkyl, or heteroaralkyl; X′ is O, N or C(R 17 ) where R 17 is a hydrogen radical or an alkyl radical; Y′ and Y″ are each independently O or S; R 4 and R 5 together with the nitrogen atom to which they are bonded represent an N-heterocyclic moiety; R 6 is a hydrogen radical or an alkyl radical; R 30 , R 31 and R 32 are each independently a radical as defined for R 1 , or one of R 1 and R 30 together with one of R 31 and R 32 and the carbon atoms to which they are bonded form a cycloalkyl; and R 33 and R 34 are each independently a radical as defined for R 3 , or R 33 and R 34 together with X′ form a radical selected from the group consisting of cycloalkyl, aryl, heterocyclyl and heteroaryl, provided that when X′ is O, R 34 is absent.