Patent ID: 7045527

Claim:
A compound of formula: or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof, wherein A represents a substituted or unsubstituted benzene ring ring; B is substituted or unsubstituted carbazolyl; L is (C 1 –C 4 )alkylene; X and Y are each independently CH or CH2 wherein the C is optionally substituted with —OR 3 , —N(R 3 )COR 4 , —C(O)NR 3 R 4 , —N(R 3 )CO 2 R 4 , —N(R 3 )C(O)N(R 4 )R 5 , or —(O); R 1 and R 2 are independently selected from the group consisting of H, (C 1 –C 4 )alkyl, (C 2 –C 8 )alkenyl, (C 2 –C 8 )alkynyl, (C 1 –C 8 )heteroalkyl, aryl, aryl(C 1 –C 4 )alkyl, —NR 6 C(O)R 5 , —C(O)R 5 and —NR 5 C(O)NHR 6 ; each R b is selected from the group consisting of (C 1 –C 4 )alkyl, aryl, OR 7 , C(O)R 7 and C(O)NR 7 R 8 ; R 3 and R 4 are independently selected from the group consisting of H, (C 1 –C 8 )alkyl, hetero(C 1 –C 8 )alkyl, aryl, aryl(C 1 –C 4 )alkyl, C(O)R′, CO 2 R′ and C(O)NR′R″; R 5 , R 6 , R 7 and R 8 are independently selected from the group consisting of H, (C 1 –C 8 )alkyl, C(O)R′″, CO 2 R′″, aryl and aryl(C 1 –C 4 )alkyl; optionally, R 7 and R 8 may be combined with the nitrogen to which each is attached to form a 5-, 6- or 7-membered ring; R′, R″ and R′″ are independently selected from the group consisting of H, (C 1 –C 8 )alkyl, aryl and aryl(C 1 –C 4 )alkyl; and the subscript p is an integer of from 0 to 4.