Patent ID: 8889744

Claim:
A pharmaceutical composition composition a therapeutically-effective amount of a compound of the following formula: wherein R 1 is H, alkyl phosphate, dichloroacetate, trifluoromethyl, or valproate, R 2 is H, alkyl, aryl, arylalkyl, or alkylaryl, and when bonded to carbon, halo, such as fluoro, Y is N or C bonded to a substituent, G, G is a substituent selected from the group consisting of C 1-6 alkyl, alkenyl, heterocyclyl, aryl, heteroaryl, halo, —OR′, —NR 3 R 4 , —CF 3 , —CN, —NO 2 , —C 2 R 3 , —S R 3 , —N 3 , —C(═O)NR 3 R 4 , —NR 3 C(═O)R 3 , —C(═O)R 3 , —C(═O)OR 3 , —OC(═O)R 3 , —OC(═O)NR 3 R 4 , —NR 3 C(═O)OR 3 , —SO 2 R 3 , —SO 2 NR 3 R 4 , and —NR 3 SO 2 R 3 , where R 3 and R 4 are individually hydrogen, C 1-6 alkyl, cycloalkyl, heterocyclyl, aryl, or arylalkyl, and z is an integer of from 0-3, but in any case cannot exceed the number of carbon atoms in the ring, and a pharmaceutically-acceptable carrier or excipient, wherein the therapeutic amount of the compound is that which provides a dosage of between about 1 and about 500 micrograms (μg) per patient per day.