Patent ID: 7632801

Claim:
A method for inhibiting or reducing influenza A virus growth, comprising contacting a first composition comprising a cell and an influenza A virus with a second composition comprising a compound that inhibits or reduces the interaction between amino acid residues 2 to 20 of an influenza A virus nucleoprotein (NP) and nucleoprotein interactor 1 (NPI-1), wherein the compound is a polypeptide which comprises the amino acid sequence of the formula Ala Xaa 2 Xaa 3 Gly Thr Lys Arg Xaa 8 Tyr Xaa 10 Gln Met Glu Thr Xaa 15 Gly Xaa 17 Arg Xaa 19 (SEQ ID NO: 44) or Xaa 2 Xaa 3 Gly Thr Lys Arg Xaa 8 Tyr Xaa 10 Gln Met (SEQ ID NO: 45), wherein Xaa 2 is Ser or Thr, Xaa 3 is Gln or Lys, Xaa 8 is Ser or Pro, Xaa 10 is Glu or Gly, Xaa 15 is Asp or Gly, Xaa 17 is Glu or Asp, and Xaa 19 is Gln or is absent.