Patent ID: 8785436

Claim:
A compound of formula I, wherein X is selected from the group consisting of aryl, aryl substituted by 1-2 substituents individually selected from R 1 , heteroaryl, heteroaryl substituted by 1-2 substituents individually selected from R 1 and halogen-aryl, C 3-6 -cycloalkyl, and C 3-6 -cycloalkyl substituted by 1-2 substituents individually selected from R 1 ; Y is selected from the group consisting of —C═O—NH—, —CH 2 —, —NH— —NH—CHR 7 —, —O—CH 2 —, and absent; Z is selected from the group consisting of aryl, aryl substituted by 1-2 substituents individually selected from R 8 , heteroaryl, heteroaryl substituted by 1-2 substituents individually selected from R 8 , C 3-6 -cycloalkyl, C 3-6 -cycloalkyl substituted by 1-2 substituents individually selected from R 8 , heterocyclyl, heterocyclyl substituted by 1-2 substituents individually selected from R 8 , C 2-6 -alkynyl, C 1-6 -alkyl, and C 1-6 -alkyl substituted by 1-3 substituents individually selected from R 9 ; R 1 is selected from the group consisting of hydrogen, halogen, and C 1-6 -alkyl; R 2 is selected from the group consisting of hydrogen, C 1-6 -alkyl, and halogen-C 1-3 -alkyl; R 3 is selected from the group consisting of hydrogen, halogen, and C 1-6 -alkyl; R 4 is selected from the group consisting of hydrogen halogen, and C 1-6 -alkyl; R 5 is selected from the group consisting of hydrogen and C 1-6 -alkyl; R 6 is selected from the group consisting of hydrogen and C 1-6 -alkyl; R 7 is selected from the group consisting of hydrogen and C 1-6 -alkyl; R 8 is selected from the group consisting of halogen, cyano, C 1-6 -alkyl, halogen-C 1-6 -alkyl, C 1-6 -alkoxy, halogen-C 1-6 -alkoxy, aryl, halogen-aryl, and C 3-6 -cycloalkyl; and R 9 is selected from the group consisting of halogen, cyano, C 1-6 -alkoxy, and halogen-C 1-6 -alkoxy; or a pharmaceutically acceptable salt thereof.