Patent ID: 8524458

Claim:
A method of identifying a high efficiency cell or cell culture comprising: (a) determining the expression level of a high efficiency cell or cell culture biomarker panel in the cell or cell culture, wherein said biomarker panel comprises guanine binding protein subunit beta 1, heat shock protein beta 1, and 14-3-3 protein zeta/delta, and (b) comparing the expression level of that high efficiency cell or cell culture biomarker panel in the cell or cell culture to the expression level of the biomarker panel in a known high efficiency cell or cell culture, wherein an expression level of heat shock protein beta 1, and 14-3-3 protein zeta/delta higher than the level in the known high efficiency cell or cell culture and an expression level of guanine nucleotide binding protein subunit beta 1 less than the level in the known high efficiency cell or cell culture is indicative of a high efficiency cell or cell culture.