Patent ID: 7105567

Claim:
A urea derivative of the formula (1) wherein R 1 , R 2 and R 3 are the same or different and each is hydrogen, alkyl optionally having a substituent, cycloalkyl optionally having a substituent, alkenyl optionally having a substituent, alkynyl optionally having a substituent, hydroxy, alkoxy optionally having a substituent, mercapto, alkylthio optionally having a substituent, halogen, nitro, nitrile, amino, alkylamino, cyclic amino, alkylsulfonyl, carbamoyl, acylamino, sulfamoyl, acyl, carboxy, alkoxycarbonyl, aryl optionally having a substituent or heteroaryl optionally having a substituent, D is a bond or alkylene optionally having a substituent, A is alkyl optionally having a substituent, cycloalkyl optionally having a substituent, aryl optionally having a substituent or heteroaryl optionally having a substituent, R 4 and R 5 are the same or different and each is alkyl optionally having a substituent, alkoxy optionally having a substituent, hydroxy or halogen, R 6 is hydrogen, alkyl optionally having a substituent, alkoxy optionally having a substituent, hydroxy or halogen, and X is oxygen atom or sulfur atom, or a pharmaceutically acceptable salt thereof, wherein the urea derivative is a non-heterocyclic.