Patent ID: 8680328

Claim:
A process for producing an optically active cyclopropanecarboxylic acid ester compound represented by the formula (4): (wherein R 5 , R 6 and * each represents the same meaning as defined below), comprising reacting a diazoacetic acid ester represented by the formula (2): N 2 CHCO 2 R 5 (2) (wherein R 5 represents an alkyl group having 1 to 15 carbon atoms or an aryl group having 6 to 10 carbon atoms) with a compound represented by the formula (3): (wherein R 6 represents an alkyl group having 1 to 15 carbon atoms, an aryl group having 6 to 10 carbon atoms or an aralkyl group having 7 to 20 carbon atoms), in the presence of an asymmetric copper complex obtained by reacting a copper compound and an optically active salicylideneaminoalcohol compound represented by the formula (1): (wherein R 1 represents an alkyl group having 2 to 4 carbon atoms, an aryl group having 6 to 10 carbon atoms or an aralkyl group having 7 to 20 carbon atoms, R 2 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 10 carbon atoms, R 3 represents a hydrogen atom, a nitro group or a bromine atom, R 4 represents a hydrogen atom or a nitro group, and * represents an asymmetric center); wherein the optically active cyclopropanecarboxylic acid ester compound has a cis form ratio (ratio (%) of a cis form relative to a total of a cis form and a trans form) of 85% or more.