Patent ID: 7105539

Claim:
A compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein A is a zinc ligand or zinc ligand bearing moiety selected from the group consisting of: B is absent: R is hydrogen or lower alkyl; R 1 is hydrogen or lower alkyl; R 2 is hydrogen, or lower alkyl; R 3 is hydrogen or lower alkyl; R 4 is lower alkyl, substituted lower alkyl, cycloalkyl-(CH 2 ) w —, aryl-(CH 2 ) w —, substituted aryl —(CH 2 ) w — or heteroaryl-(CH 2 ) w —; R 5 is hydrogen, lower alkyl, substituted lower alkyl, cycloalkyl-(CH 2 ) x —, aryl-(CH 2 ) x —, substituted aryl-(CH 2 ) x —, or heteroaryl-(CH 2 ) x —; R 8 and R 9 are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, aryl-(CH 2 ) y —, substituted aryl-(CH 2 ) y —, heteroaryl-(CH 2 ) y —, R 10 is alkyl, substituted alkyl, cycloalkyl-(CH 2 ) y , aryl-(CH 2 ) y —, substituted aryl-(CH 2 ) y — or heteroaryl-(CH 2 ) y —; R 13 is hydrogen, lower alkyl, cycloalkyl or phenyl; R 14 is hydrogen, lower alkyl, lower alkoxy or phenyl; R 15 is lower alkyl or aryl-(CH 2 ) y —; D is —COOH, E is hydrogen, —COOH, —CONH 2 , —CONH(lower alkyl), —CON(lower alkyl) 2 , —CONH—(CH 2 ) z -aryl, —CON(—(CH 2 ) z -aryl) 2 , —CO-amino acid, —CH 2 COOH, CH 2 OH, —CH 2 CH 2 OH, or —COOR 16 ; R 16 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, aryl-(CH 2 ) y —, substituted aryl-(CH 2 ) y —, heteroaryl-(CH 2 ) y —, C is carbon; H is hydrogen; O is oxygen; N is nitrogen; S is sulfur; P is phosphorus; v is zero; w is zero or an integer ranging from 1 to 4; x is an integer ranging from 1 to 4; y is zero or an integer ranging from 1 to 6; and z is zero, one, two, or three.