Patent ID: 7863305

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: p is 1; Ar is: indolyl selected from indol-1-yl, indol-2-yl and indol-3-yl, each optionally substituted; 2,3-dihydroindolyl selected from 2,3-dihydroindol-1-yl, 2,3-dihydroindol-2-yl and 2,3-dihydroindol-3-yl, each optionally substituted; indazolyl selected from indazol-1-yl, indazol-2-yl and indazol-3-yl, each optionally substituted; benzimidazolyl selected from benzimidazol-1-yl and benzimidazol-2-yl, each optionally substituted; benzofuranyl selected from benzofuran-2-yl and benzofuran-3-yl, each optionally substituted; benzothiophenyl selected from benzothiophen-2-yl and benzothiophen-3-yl, each optionally substituted; optionally substituted benzoxazol-2-yl; or optionally substituted benzothiazol-2-yl; R 1 is: aryl selected from phenyl and naphthyl, each optionally substituted; heteroaryl selected from thienyl, furanyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, imidazolyl, pyrazolyl quinolinyl and isoquinolinyl, each optionally substituted; optionally substituted arylalkyl; optionally substituted heteroarylalkyl; cycloalkyl; cycloalkylmethyl; or branched alkyl; one of R 2 and R 3 is hydrogen and the other is alkyl; R a is: hydrogen; fluoro; or alkyl; R b is: hydrogen; alkyl; hydroxy; alkoxy; fluoro; or hydroxyalkyl; R c and R d each independently is: hydrogen; or alkyl; and R e is hydrogen or alkyl.