Patent ID: 8362056

Claim:
A compound of general Formula I: or a salt thereof, wherein: D 1 is N or CR 9 and D 2 is N or CR 10 , wherein at least one of D 1 and D 2 is not N; R 1 is Ar 1 -L 1 -W-L 2 -; L 2 is —(CR c R d ) m -; W is —CONR 3a —, —NR 3b CO— or —SO 2 NR 3c —; R 3a , R 3b and R 3c are each H or methyl; L 1 is —(CR a R b ) n — or —(CR a R b )O—; n and m are independently 0, 1 or 2; each R a , R b , R c and R d is independently H, F, methyl or cyclopropyl, or R a and R b or R c and R d together with the carbon to which they are attached form a cyclopropyl ring; Ar 1 is phenyl, naphthyl, or 2,3-dihydro-1H-indenyl, each of which is unsubstituted or substituted with one or more groups independently selected from F, Cl, CN, CF 3 , CHF 2 , CH 2 F, SF 5 , methyl, ethyl and cyclopropyl, provided that when Ar 1 is naphthyl or 2,3-dihydro-1H-indenyl then n is 0; R 2 is H or C 1 -C 6 alkyl; A is CN, CH 2 NH 2 , CH 2 NR 4a C(═O)R 5 , CH 2 NR 4b SO 2 R 6 , or Cl; R 4a and R 4b are each H or methyl; R 5 is C 1 -C 6 alkyl, C 1 -C 6 alkoxy, or C 3 -C 6 cycloalkyl; R 6 is C 1 -C 6 alkyl, NH(C 1 -C 6 alkyl), or N(C 1 -C 6 alkyl) 2 ; R 7 and R 8 are independently H or methyl; and R 9 and R 10 are independently H, methyl, ethyl, isopropyl, CF 3 , or cyclopropyl.