Patent ID: 6858740

Claim:
Process for preparing a compound of formula (B) wherein X is —CONR 5 R 6 or —COOR 7 or —CO—R 8 or CN; R 1 is hydrogen or alkyl, aryl, heterocycloalkyl, heteroaryl, halogen, hydroxy, amino, nitro, or cyano; R 2 , R 4 are the same or different and each is independently hydrogen or halogen, hydroxy, amino, nitro, cyano, acyl, acyloxy, sulfonyl, sulfinyl, alkylamino, carboxy, ester, ether, amido, sulfonic acid, sulfonamide, alkylsulfonyl, arylsulfonyl, alkoxycarbonyl, alkylsulfinyl, arylsulfinyl, alkylthio, arylthio, alkyl,alkoxy, oxyester, oxyamido, aryl, arylamino, aryloxy, heterocycloalkyl, heteroaryl, or vinyl; R 3 is hydrogen, halogen, hydroxy, amino, nitro, cyano, acyl, acyloxy, sulfonyl, sulfinyl, alkylamino, carboxy, ester, ether, amido, sulfonic acid, sulfonamide, alkylsulfonyl, arylsulfonyl, alkoxycarbonyl, alkylsulfinyl, arylsulfinyl, alkylthio, arylthio, alkyl, alkoxy, oxyester, oxyamido, aryl, arylamino, aryloxy, heterocycloalkyl, heteroaryl, (C2-C5)alkenyl, (C2-C5)alkynyl, azido, or phenylsulfonyloxy; R 5 , R 6 , R 7 are the same or different and each is independently hydrogen, hydroxy, alkyl, aryl, heterocycloalkyl, heteroaryl, alkoxy, or aryloxy; and R 8 is hydrogen, hydroxy, thiol, halogen, alkyl, aryl, heterocycloalkyl, heteroaryl, alkylthio, or arylthio; each alkenyl, alkynyl, and azido may independently be optionally substituted by one or more halogen, cyano, thiocyano, azido, alkylthio, cyclopropyl, acyl, or phenyl; which comprises reacting a compound of general formula (A), wherein R 1 , R 2 , R 3 , R 4 and X have the same meanings defined above, according to the following Scheme (6):