Patent ID: 7682799

Claim:
A method of detecting the presence of a midbody scar in a mammalian cell, the method comprising: contacting a mammalian cell suspected to have a midbody scar with an antibody or antigen-binding portion thereof that binds specifically to a polypeptide component of a midbody scar selected from the group consisting of mitotic kinesin-like protein 1 (MKLP1), Epsilon tubulin (ε-tubulin), Centrosomal Protein 55 kDa (Cep55), and Aurora B kinase; detecting binding of the antibody to its antigen; and identifying a midbody scar in the mammalian cell if binding of the antibody to its antigen is detected in a ring structure not at a midbody or centrosome, thereby detecting a midbody scar.