Patent ID: 8168795

Claim:
A compound having a structure wherein R 1 and R 2 are each independently selected from H, C 1 -C 4 alkyl; C is a phenyl, aryl or heteroaryl, having a structure and p is 0-1 and Z 1 -Z 6 are each independently selected from C, N, O and S; R 3 and R 8 are each independently selected from H, C 1 -C 6 straight or branched chain alkyl, alkenyl, or alkynyl, alkoxy (such as O(C 1 -C 6 )), —OH, halogen, —NR 4 2 , —CN, —CO 2 R 4 , —C(O)NR 4 R 5 , —CH 2 OH, —CF 3 , —OCHF 2 , —OCF 3 , —NO 2 , alkylamino, and alkylcarboxyl; m is 0-5; n is 0-5; R 4 and R 5 are each independently selected from H, C 1 -C 6 , branched or unbranched alkyl, alkenyl, or alkynyl, C 3 -C 6 saturated or unsaturated cyclic hydrocarbon, aryl, heteroaryl, haloalkyl, hydroxyl, alkoxyl, hydroxyalkyl, alkylcarbonyl, formyl, oxycarbonyl, carboxyl, alkyl carboxylate, alkylamide, alkylamino aminocarbonyl, or amino; A is CR 6 3 , CXR 6 2 , CX 2 R 6 , CX 3 , COQ 1 , SOQ 1 , SO 2 Q 1 , CSQ 1 , amide, sulfonyl, sulfone, sulfonamide, sulfoxide, ester, thiocarbonyl, phenyl, substituted phenyl, heterocylic, heteroaromatic, cycloalkyl, and cycloalkenyl; X is a halogen; R 6 is H, C 1 -C 6 straight or branched chain alkyl, alkenyl, or alkynyl, haloalkyl, perfluorinated alkyl, partially fluorinated alkyl, perhalogenated alkyl, partially halogenated alkyl; Q 1 is an aryl or heteroaryl variably substituted with (R 3 ) n , a phenyl, heteroaromatic or cycloalkyl, cycloalkenyl, or partially saturated or saturated heterocyclic ring a bicyclic compound, NR 4 R 5 ; R 7 is H, C 1 -C 6 branched or unbranched alkyl, alkenyl, or alkynyl, haloalkyl, aryl, herteoaryl, perfluorinated alkyl and partially fluorinated alkyl, perhalogenated alkyl, partially perhalogenated alkyl, phenyl, cyano, ketyl, CF 3 , substituted aryl or heteroaryl and spirocyclic compounds; and B is phenyl, aryl, heteroaromatic or cycloalkyl, cycloalkenyl, or partially saturated or saturated heterocyclic ring, or a bicyclic compound, with the proviso that when A is CX 3 , B is not phenyl.