Patent ID: 8420848

Claim:
A process for the preparation of a compound of Formula (VI), the process comprising: (a) contacting a compound of Formula (I) with a protecting agent comprising R p to form a compound of Formula (II) (b) contacting the compound of Formula (II) with a phosphorylating agent comprising Z in the presence of a proton acceptor to form a compound of Formula (III) (c) contacting the compound of Formula (III) with water to form HZ and a compound of Formula (IV) (d) contacting the compound of Formula (IV) with a proton acceptor comprising at least one metal ion (M) to form a compound of Formula (V) (e) deprotecting the compound of Formula (V) to form the compound of Formula (VI); wherein: R p is a protecting group; Z is halogen; and M is selected from the group consisting of Group IA, Group IIA, and transition metal ions.