Patent ID: 7335666

Claim:
A compound of Formula I: wherein Q is R 1 , R 2 and R 3 are, independently, hydrogen, hydroxy, halo, cyano, carboxamido, carboalkoxy of two to six carbon atoms, trifluoromethyl, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alkanoyl of 2 to 6 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, alkanesulfonyl of 1 to 6 carbon atoms or alkanesulfonamido of 1 to 6 carbon atoms; X and Y are, independently, hydrogen, hydroxy, halo, cyano, carboxamido, carboalkoxy of two to six carbon atoms, trifluoromethyl, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alkanoyl of 2 to 6 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, alkanesulfonyl of 1 to 6 carbon atoms or alkanesulfonamido of 1 to 6 carbon atoms, or X and Y, taken together, form —N═C(R 4 )—C(R 5 )═N—, —N═C(R 4 )—N═CH—, —N═C(R 4 )—O—, —NH—C(R 7 )═N— or —NH—C(R 8 )═CH—; R 4 and R 5 are, independently, hydrogen, halo, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms or alkyl of 1 to 6 carbon atoms; R 7 is hydrogen, halo, trifluoromethyl, pentafluoroethyl, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms or alkyl of 1 to 6 carbon atoms; R 8 is hydrogen, halo, trifluoromethyl, pentafluoroethyl, or alkyl of 1 to 6 carbon atoms; Z is O, S, or NR 9 , in which R 9 is hydrogen or alkyl of 1 to 6 carbon atoms; n is an integer 0, 1, or 2; m is an integer from 1 to 4, provided that m+n≦4 and that when m=n=2, and Q is b then X and Y are not NH—C(R 8 )═CH—; and p is an integer from 1 to 3, provided that p+n is 2 or 3; or a pharmaceutically acceptable salt thereof.