Patent ID: 8796260

Claim:
A compound of formula (II): wherein: A is NR 5 or C(R 5 ) 2 ; Z is selected from: and when A is NR 5 , Z is additionally selected from: R 1A and R 1B are independently selected from: 1) H, C 1 -C 6 alkyl, C 3-6 cycloalkyl and heterocycle, wherein said alkyl, cycloalkyl and heterocycle is optionally substituted with one or more substituents each independently selected from: a) C 1-6 alkyl, b) C 3-6 cycloalkyl, c) aryl, unsubstituted or substituted with 1-5 substituents where the substituents are independently selected from R 5 , d) heteroaryl, unsubstituted or substituted with 1-5 substituents each independently selected from R 5 , e) heterocycle, unsubstituted or substituted with 1-5 substituents each independently selected from R 5 , f) (F) p C 1-3 alkyl, g) halogen, h) OR 5 , i) O(CH 2 ) s OR 5 , j) CO 2 R 5 , k) CN, l) NR 10 R 11 , and m) O(CO)R 5 ; and 2) aryl or heteroaryl, wherein said aryl or heteroaryl is optionally substituted with one or more substituents independently selected from: a) C 1-6 alkyl, b) C 3-6 cycloalkyl, c) (F) p C 1-3 alkyl, d) halogen, e) OR 5 , f) CO 2 R 5 , g) (CO)NR 10 R 11 , h) SO 2 NR 10 R 11 , i) N(R 10 ) SO 2 R 11 , j) S(O) m R 5 , k) CN, l) NR 10 R 11 , and m) O(CO)R 4 ; R 4 is hydrogen, halo, C 1-6 alkyl, or C 2-6 alkenyl; R 5 is selected from: H, C 1-6 alkyl, C 3-6 cycloalkyl, aryl, heteroaryl and benzyl, wherein said alkyl, cycloalkyl, aryl or heteroaryl moiety is optionally substituted with halogen, hydroxy or C 1 -C 6 alkoxy; R 10 and R 11 are independently selected from: H, C 1-6 alkyl, C 3-6 cycloalkyl, aryl, heteroaryl and benzyl, wherein said alkyl, cycloalkyl, aryl or heteroaryl moiety is optionally substituted with halogen, hydroxy or C 1 -C 6 alkoxy, provided that when R 10 and R 11 are bonded to the same nitrogen atom, then R 10 and R 11 and the nitrogen to which they are both attached form a ring selected from: azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl and morpholinyl, which ring is unsubstituted or substituted with 1-5 substituents each independently selected from R 5 ; p is 0 to 2q+1, for a substituent with q carbons m is 0 to 2; s is 1 to 3 or a pharmaceutically acceptable salt thereof, or individual stereoisomer thereof.