Patent ID: 7019000

Claim:
A method of treating a disease condition caused or exacerbated by an HPV wherein said disease condition is cervical cancer or precursor lesions thereof, asymptomatic infections of the cervix and genital, common, plantar or planar warts, comprising the administration to a mammal in need thereof of an effective amount of a compound which facilitates disruption of a chelated metal cation domain of a protein encoded for by an HPV gene, wherein the compound is selected from the group of compounds consisting of formulae (I): wherein n is selected from 1–5 R 1 –R 4 are independently selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted arylalkyl optionally substituted acyl, optionally substituted heterocyclyl, halo alkyl, arylalkyl, carboxy, carboxy ester and carboxamido; or R 1 and R 2 together, and/or R 3 and R 4 together, independently form a group of formula (a): (CH 2 ) l —U m —(CH 2 ) n — (a) wherein: U is CH 2 , O, NH or S; l and n are independently selected from 0 to 6 and m is 0 or 1 when U is CH 2 and m is 1 when U is O, NH or S, such that l+m+n is greater than or equal to 2; and wherein any one or more (CH 2 ) or NH groups may be further optionally substituted or a pharmaceutically acceptable derivative thereof.