Patent ID: 7611839

Claim:
A method for confirming a diagnosis of renal cell carcinoma (RCC) in a human, the method comprising the steps of: a) providing at least one peripheral blood sample of a human; b) generating an expression profile comprising expression levels of two RCC disease genes in said at least one peripheral blood sample of the human; c) comparing the expression profile generated in step b) to at least one reference expression profile comprising expression levels of said two RCC disease genes wherein the reference expression profile is obtained from peripheral blood samples from patients having RCC or peripheral blood samples from disease-free humans, wherein said comparison is used to indicate the presence or absence of RCC in the human; and wherein (i) the human has a prior diagnosis of RCC and (ii) said two RCC disease genes are eukaryotic elongation factor 1 alpha 2 (EEF1A2, SEQ ID NO:285) and toll-like receptor 2 (TLR2, SEQ ID NO:1).