Patent ID: 8750968

Claim:
A device for a diagnosis and/or therapy monitoring of inflammatory diseases, comprising: at least a housing with a rest or a support device ( 1 ) for holding two extremities ( 11 ) of a person, at least one excitation source ( 2 ) for at least partially illuminating ( 11 ) with radiation of at least one defined excitation wavelength, wherein said excitation wavelength is selected from the wavelength range of 650 nm to 900 nm, at least one image sensor ( 3 ) for capturing at least one reference signal from at least one of said two extremities ( 11 ) and a plurality of signals from the regions of medical interest (ROI) of at least one of said two extremities ( 11 ), and a comparator ( 4 ) for comparing said at least one reference signal with the plurality of signals from the regions of medical interest (ROI), wherein said comparator ( 4 ) is configured to compare an area under the curve value (AUC value) from said at least one reference signal to determine a mean AUC reference value (mean AUC REF ) and a correction factor (CF) from the equation 100=mean AUC REF /CF, and an area under the curve value, determined for each of said plurality of signals from the regions of medical interest (ROI), and a corrected AUC value (AUC CORR value) is then determined for each of said plurality of signals from the regions of medical interest (ROI) using the equation AUC CORR =AUC/CF, and the AUC CORR value can be used to diagnose and/or therapy monitor the inflammatory diseases, wherein both said at least one reference signal and said plurality of signals from the region of medical interest originate from one extremity, and wherein the device is suitable for comparing the detected signals on the basis of the fluorescence of an administered dye by means of the comparator ( 4 ).