Patent ID: 8790684

Claim:
A vascular closure device comprising: a preshaped, cylindrical fibrous plug formed prior to delivery from a non-woven fabric of at least one randomly oriented and entangled fiber, the thickness of the nonwoven fabric ranging from about 0.25 to 2 mm, the basis weight of the nonwoven fabric ranging from about 0.01 to 0.2 g/in 2 , the at least one randomly oriented fiber having a density from about 120 to about 150 denier and a tenacity from about 3 to about 7 g/denier, the cylindrical fibrous plug being configured for occluding blood flow from a puncture and sealing a wound in a tract of a puncture wound, the fibrous plug having a definite cylindrical shape and volume ex vivo, the randomly oriented fiber comprising at least one polymer; and at least one agent, in therapeutic dosage, dispersed in the fiber matrix of the at least one randomly oriented fiber, and configured for controlled elution therefrom.