Patent ID: 7405270

Claim:
A soluble C40-L polypeptide (CD40-L) that binds CD40 and lacks a CD40-L tranamembrane region, wherein the CD40-L polypeptide is encoded by a nucleic acid selected from the group consisting of: (a) a polynucleotide comprising nucleotides 184 through 828 of SEQ ID NO:11; (b) a polynucleotide comprising nucleotides 196 through 828 of SEQ ID NO:11; (c) a polynucleotide comprising nucleotides 403 through 828 of SEQ ID NO:11; (d) a polynucleotide comprising nucleotides 382 through 828 of SEQ ID NO:11; and (e) a polynucleotide comprising nucleotides 379 through 828 of SEQ ID NO:11; wherein the CD40-L polypeptide lacks native-pattern glycosylation.