Patent ID: 7285363

Claim:
A method for crosslinking one or more molecules, comprising photoactivating a photactivatable crosslinker in the presence of the one or more molecules by multi-photon excitation, wherein the crosslinker comprises at least two photoactive groups covalently linked by a bridging moiety, and further wherein the point volume of the activation produces a structural element that has at least one dimension of less than about 1 micron; and crosslinking the one or more molecules with the activated crosslinker, wherein the crosslinking produces a three-dimensional structure, wherein the photoactive groups are selected from the group consisting of benzophenones, triazines, chromophore-substituted halomethyl-s-triazines, pyrazines, pyrimidines, pyradizines, benzotriazoles, nitrobenzenes, phenyldiazenes, pyridazine diones, phthalazine diones, and a combination comprising at least one of the foregoing photoactive groups.