Patent ID: 8734852

Claim:
A stable controlled release parenteral formulation for treatment of pain and inflammation, said formulation comprising an effective amount of: at least one active drug moiety, wherein said at least one active drug moiety is selected from the group consisting of aceclofenac, diclofenac, and a combination thereof; at least one solvent moiety, wherein said at least one solvent moiety is selected from the group consisting of triacetin, dimethyl isosorbide, and a combination thereof, wherein said formulation, upon administration, has a release profile comprising an immediate burst release; wherein said immediate burst release is followed by a sustained release of at least 18 to 24 hrs; wherein said immediate burst release and said sustained release of said drug moiety remains within a therapeutic window of said at least one active drug moiety; wherein said dimethyl isosorbide is present in a range of about 0.05 ml to about 0.7 ml: wherein said triacetin is present in a range of about 0.3 ml to about 3.0 ml; and wherein said at least one solvent and said at least one active drug moiety are present as a single unit injection.