Patent ID: 7060718

Claim:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein X is a member selected from the group consisting of O, S and NH; R 1 and R 2 are each members independently selected from the group consisting of hydrogen, (C 1 –C 6 )alkyl and (C 1 –C 6 )heteroalkyl; R 3 is a member selected from the group consisting of hydrogen, (C 1 –C 6 )alkyl and (C 1 –C 6 )heteroalkyl, or is combined with Y and the nitrogen atom to which each is attached to form a 5-, 6- or 7-membered heterocyclic ring; R 4 is a member selected from the group consisting of hydrogen, halogen, (C 1 –C 8 )alkyl, (C 1 –C 8 )heteroalkyl, —OR 11 , —SR 11 and —NR 11 R 12 , wherein R 11 and R 12 are each independently selected from the group consisting of hydrogen, (C 1 –C 8 )alkyl and (C 1 –C 8 )heteroalkyl; Y is a member selected from the group consisting of hydrogen, a heterocyclic ring, (C 1 –C 8 )alkyl, (C 1 –C 8 )heteroalkyl, aryl, aryl(C 1 –C 4 )alkyl, aryl(C 1 –C 4 )heteroalkyl, heterocyclyl(C 1 –C 4 )alkyl and heterocyclyl(C 1 –C 4 )heteroalkyl, or is optionally linked together with R 3 to form a 5-, 6- or 7-membered heterocyclic ring; and Ar is a member selected from the group consisting of: wherein X 1 and X 2 are each independently selected from the group consisting of F, Cl and Br.