Patent ID: 7498352

Claim:
A method for promoting the production and/or secretion of a TGF-β superfamily protein in a mammal, which comprises administering a compound represented by the formula: wherein R 1 is a halogen atom, an optionally substituted heterocyclic group, an optionally substituted hydroxy group, an optionally substituted thiol group or an optionally substituted amino group; A is an optionally substituted formyl group, an optionally substituted C 1-10 alkyl-carbonyl group, an optionally substituted C 3-10 cycloalkyl-carbonyl group, an optionally substituted C 2-10 alkenyl-carbonyl group, an optionally substituted C 3-10 cycloalkenyl-carbonyl group, an optionally substituted C 6-12 aryl-carbonyl group, an optionally substituted phosphono group, an optionally substituted heterocyclic group, an optionally substituted hydroxy group or an optionally esterified carboxyl group; B is an optionally substituted aromatic group; X is an oxygen atom; and Y is a divalent hydrocarbon group or heterocyclic group, or a salt thereof to the mammal.