Patent ID: 8236809

Claim:
A compound of the Formula (I) het -X-AB (I) where het is five-membered or six-membered N-heteroaryl or fused five-membered or six-membered N-heteroaryl, wherein N-heteroaryl is optionally substituted, wherein the five-membered heteroaryl is selected from the group of imidazolyl, oxazolyl, isoxazolyl, thiazolyl, oxadiazolyl, thiadiazolyl, tetrazolyl, oxatriazolyl, and thiatriazolyl, and wherein six-membered N-heteroaryl is selected from the group consisting of pyrimidinyl, pyrazinyl, pyridazinyl, 1,2,3-triazinyl, 1,2,4-triazinyl, and 1,3,5-triazinyl; X is S; and where the N-atom of the N-heteroaryl moiety and the —X group are separated by one carbon atom; AB is the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl radical of the Formula (II) wherein AB is bound to X via the 4-position of the pyrimidine ring, wherein R3 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, aralkyl, alkenyl, cyclo-alkenyl, and alkynyl, wherein at least one atom of alkyl, cycloalkyl, aryl, aralkyl, alkenyl, cyclo-alkenyl, or alkynyl is optionally substituted with one or more elements selected from the group consisting of O, S, N, F, Cl, Br, and I; and R5 is selected from the group consisting of hydrogen, (C 1 -C 8 ) alkyl, (C 3 -C 6 ) cycloalkyl, benzyl, phenyl, F, Cl, Br, I, OH, R4—S, R4—O, and NR 1 R 2 , wherein R4 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, aralkyl, alkenyl, cyclo-alkenyl, and alkynyl, wherein at least one atom of alkyl, cycloalkyl, aryl, aralkyl, alkenyl, cyclo-alkenyl, or alkynyl is optionally substituted with one or more elements selected from the group consisting of O, S, N, F, Cl, Br, and I, and R 1 and R 2 are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, aralkyl, alkenyl, cyclo-alkenyl, and alkynyl, wherein at least one atom of alkyl, cycloalkyl, aryl, aralkyl, alkenyl, cyclo-alkenyl, or alkynyl is optionally substituted with one or more elements selected from the group consisting of O, S, N, F, Cl, Br, and I, or where R 1 and R 2 form together a ring system; or a pharmaceutically acceptable salt thereof.