Patent ID: 7741297

Claim:
A method of stimulating the immune system of a subject which comprises administering to the subject an immunologically effective amount of an isolated immunostimulatory molecule which comprises at least one oligonucleotide strand which comprises (1) at least one nucleotide sequence comprising a plurality of nucleotides, each nucleotide comprising a nucleobase, and thereby also comprising at least one CxG dinucleotide unit or analogue thereof, in which there are no more than six nucleobases in each oligonucleotide strand, wherein in said analogue, (1) cytosine is replaced with a cytosine analogue which is a pyrimidine other than thymine or uracil, and/or (2) guanine is replaced with a guanine analogue which is a purine other than adenine, and (2) at least one covalently incorporated lipophilic group.