Patent ID: 8039492

Claim:
A substituted cyclic compound of the following general formula I or II or pharmaceutically acceptable salts thereof: wherein: n is 0 or 1; X and Y are NH; wherein, R 1 and R 2 independently are one of the substituents selected from the group consisting of: aryl; 2-, 3- or 4-pyridyl; aryl substituted with one, two or three groups selected from C 1 -C 4 alkyl, alkoxy, mercapto, methylthio, ethylthio, —O—C 1 -C 6 alkanoyl substituted with one, two or three groups selected from halogen, C 1 -C 6 alkoxy, or hydroxyl, and thienyl-2-carboxylate; and 2-, 3- or 4-pyridyl substituted with one, two or three groups selected from C 1 -C 4 alkyl, alkoxy, mercapto, methylthio, ethylthio, —O—C 1 -C 6 alkanoyl substituted with one, two or three groups selected from halogen, C 1 -C 6 alkoxy, or hydroxyl, and thienyl-2-carboxylate; and R 3 and R 4 independently are one of the substituents selected from the group consisting of: aryl; 2-, 3- or 4-pyridyl; aryl substituted with one, two or three groups selected from C 1 -C 4 alkyl, alkoxy, mercapto, methylthio, ethylthio, —NH—C 1 -C 6 alkanoyl substituted with one, two or three groups selected from halogen, C 1 -C 6 alkoxy, or hydroxyl, —NH—C 3 -C 6 cycloalkanoyl, and —NH—C 3 -C 6 cycloalkanoyl substituted with one, two or three groups selected from halogen, C 1 -C 6 alkoxy, and hydroxyl; and 2-, 3- or 4-pyridyl substituted with one, two or three groups selected from C 1 -C 4 alkyl, alkoxy, mercapto, methylthio, ethylthio, and —NH—C 1 -C 6 alkanoyl substituted with one, two or three groups selected from halogen, C 1 -C 6 alkoxy, or hydroxyl.