Patent ID: 6884804

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: G is —XR or —XAr; each X is independently selected from a C 1-4 alkylidene chain, wherein one or two non-adjacent methylene units of X are independently replaced by —S—, —SO—, —SO 2 —, —O—, or —NH—; A is N; each R is independently selected from hydrogen or an optionally substituted C 1-8 aliphatic group; Ar is an optionally substituted ring selected from phenyl, pyridyl, imidazolyl, thienyl, thiazolyl, [1,3]dioxanyl, piperidinyl, morpholinyl, pyrrolyl, pyrrolidinyl, furanyl, tetrahydrofuranyl, pyranyl, imidazolyl, benzimidazolyl, pyrrolyl, piperazinyl, thiomorpholinyl, naphthyl, oxazolyl, triazinyl, tetrazolyl, dithiolanyl, dioxalanyl, benzofuranyl, benzothienyl, or indolyl; R 1 is T (n) -R or T (n) attached to an optionally susbtituted ring selected from phenyl, cyclohexyl, pyridyl, naphthyl, quinolinyl, isoquinolinyl, or indanyl; n is zero or one; T is selected from —C(O)—, —CO 2 —, —C(O)C(O)—, —C(O)CH 2 C(O)—, —CONR—, —S(O) 2 —, or —S(O) 2 NR—; R 2 is selected from hydrogen, Ar, or a C 1-8 aliphatic group optionally substituted with 1-3 groups independently selected from oxo, OR, SR, SO 2 R, C(O)R, CO 2 R, CN, N(R) 2 , ═N—OR, ═NN(R) 2 , ═NNHC(O)R, ═NNHCO 2 R, ═NNHSO 2 R, Ar, NRC(O)N(R) 2 , NRC(O)R, NRCO 2 R, C(O)N(R) 2 , SO 2 N(R) 2 , or NRSO 2 N(R) 2 ; and R 3 is selected from R or an optionally substituted ring selected from cyclohexyl, cyclopentyl, phenyl, pyridyl, pyrimidinyl, or pyridazinyl.