Patent ID: 8703125

Claim:
A method for treating a disorder selected from the group consisting of anxiety and stress in an individual in need thereof, said method comprising administering to said individual, a therapeutically effective amount of a sortilin-related Vps10p domain-containing receptor 2 (SorCS2) modulator or a Sortilin modulator, wherein: (A) the SorCS2 modulator is an anti-SorCS2 polyclonal antibody or a fragment thereof which binds to SorCS2, or is an anti-SorCS2 monoclonal antibody or a fragment thereof which binds to SorCS2; and (B) the Sortilin modulator is an anti-Sortilin polyclonal antibody or a fragment thereof which binds to Sortilin, or is an anti-Sortilin monoclonal antibody or a fragment thereof which binds to Sortilin.