Patent ID: 7951809

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: each of Q 1 and Q 2 are independently selected from 5-6 membered aromatic carbocyclic or heterocyclic ring systems, or 8-10 membered bicyclic ring systems consisting of aromatic carbocyclic rings, aromatic heterocyclic rings or a combination of an aromatic carbocyclic ring and an aromatic heterocyclic ring; wherein: Q 1 is substituted with 1 to 4 substituents, independently selected from N(R′)C(O)R 4 ; N(R′)C(O)OR 4 ; N(R′)C(O)C(O)R 4 ; N(R′)S(O 2 )R 4 ; N(R′)R 4 ; N(R 4 ) 2 ; OR 4 ; OC(O)R 4 ; OP(O) 3 H 2 ; N═CH—N(R′) 2 ; 3,4-methylenedioxy; —NH—C(O)—O—CH 2 -4-pyridine; —NH—C(O)CH 2 -morpholine; —NH—C(O)CH 2 -piperazine; or —NH—C(O)CH 2 -pyrrolidine; and Q 2 is optionally substituted with up to 4 substituents, independently selected from halo; C 1 -C 3 straight or branched alkyl optionally substituted with NR′ 2 , OR′, CO 2 R′, S(O 2 )N(R′) 2 , N═CH—N(R′) 2 , R 3 , or CONR′ 2 ; O—(C 1 -C 3 )-alkyl optionally substituted with NR′ 2 , OR′, CO 2 R′, S(O 2 )N(R′) 2 , N═CH—N(R′) 2 , R 3 , or CONR′ 2 ; NR′ 2 ; OCF 3 ; CF 3 ; NO 2 ; CO 2 R′; CON(R′) 2 ; R 3 ; OR 3 ; NHR 3 ; SR 3 ; C(O)R 3 ; C(O)N(R′)R 3 ; C(O)OR 3 ; SR′; S(O 2 )N(R′) 2 ; SCF 3 ; N═CH—N(R′) 2 ; CN; —NH—C(═NH)—NH 2 ; —CH 2 —NH—C(═NH)—NH 2 ; or —CH 2 —NH-imidazole; wherein R′ is selected from hydrogen, (C 1 -C 3 )-alkyl; (C 2 -C 3 )-alkenyl or alkynyl; phenyl or phenyl substituted with 1 to 3 substituents independently selected from halo, methoxy, cyano, nitro, amino, hydroxy, methyl or ethyl; R 3 is selected from a 5-6 membered aromatic carbocyclic or heterocyclic ring system; and R 4 is (C 1 -C 4 )-alkyl optionally substituted with N(R′) 2 , OR′, CO 2 R′, CON(R′) 2 , or SO 2 N(R 2 ) 2 ; or a 5-6 membered carbocyclic or heterocyclic ring system optionally substituted with N(R′) 2 , OR′, CO 2 R′, CON(R′) 2 , or SO 2 N(R 2 ) 2 ; each R is independently selected from hydrogen, —R 2 , —N(R 2 ) 2 , —OR 2 , SR 2 , —C(O)—N(R 2 ) 2 , —S(O 2)—N(R 2 ) 2 , or —C(O)—OR 2 , wherein two adjacent R are optionally bound to one another and, together with each Y to which they are respectively bound, form a 4-8 membered carbocyclic or heterocyclic ring; R 2 is selected from hydrogen, (C 1 -C 3 )-alkyl, or (C 2 -C 3 ) -alkenyl; each optionally substituted with -N(R′) 2 , —OR′, SR′, —C(O)—N(R′) 2 , —S(O 2 )—N(R′) 2 , —C(O)—OR′, or R 3 ; Y is C; and R 1 is selected from hydrogen, (C 1 -C 3 )-alkyl, OH, or O—(C 1 -C 3 )-alkyl.