Patent ID: 8450349

Claim:
A method of providing relief from symptoms associated with allergic rhinitis comprising administering a single pharmaceutical dosage form that comprises: a) a therapeutically effective amount of carbinoxamine or a pharmaceutically acceptable salt thereof in an immediate release format adapted to release at least 80% of said carbinoxamine or carbinoxamine salt in 60 minutes or less when measured in a type II dissolution apparatus according to the U.S. Pharmacopoeia in 0.1N hydrochloric acid buffer (pH=2) at 37° C.; and b) a therapeutically effective amount of a second pharmaceutically acceptable agent selected from a decongestant, an antitussive, an analgesic or an expectorant in a prolonged release format adapted to release no more than 50% of said second agent in 60 minutes or less, and at least 75% of said second agent in eight hours or less, when measure in a type II dissolution apparatus according to the U.S. Pharmacopoeia in 01.N hydrochloric acid buffer (pH=2) at 37° C.; wherein said therapeutically effective amounts of said carbinoxamine or carbinoxamine salt and said second agent are sufficient to provide relief from said symptoms for at least twelve hours.