Patent ID: 8501182

Claim:
An isolated monoclonal antibody, comprising: a heavy chain (H) with a H-complementarity determining region (CDR)1, H-CDR2 and H-CDR3 region and a light chain (L) with a L-CDR1, L-CDR2 and L-CDR3 region, wherein either (a) the H-CDR1 comprises the amino acid sequence set forth as amino acids 28 to 32 of SEQ ID NO: 3, the H-CDR2 comprises the amino acid sequence set forth as amino acids 47 to 55 of SEQ ID NO: 3, and the H-CDR3 comprises the amino acid sequence set forth as amino acids 95 to 111 of SEQ ID NO: 3, and wherein the antibody has a light chain with a L-CDR1, L-CDR2 and L-CDR3 region, and wherein L-CDR1 comprises the amino acid sequence set forth as amino acids 23 to 33 of SEQ ID NO: 4, L-CDR2 comprises the amino acid sequence set forth as amino acids 48 to 55 of SEQ ID NO: 4, and L-CDR3 comprises the amino acid sequence set forth as amino acids 88 to 96 of SEQ ID NO: 4; or (b) wherein H-CDR1 comprises the amino acid sequence set forth as amino acids 27 to 31 of SEQ ID NO: 5, H-CDR2 comprises the amino acid sequence set forth as amino acids 46 to 54 of SEQ ID NO: 5, and H-CDR3 comprises the amino acid sequence set forth as amino acids 94 to 110 of SEQ ID NO: 5 and wherein the antibody has light chain with a L-CDR1, L-CDR2 and L-CDR3 region, and wherein L-CDR1 comprises the amino acid sequence set forth as amino acids 22 to 32 of SEQ ID NO: 6, L-CDR2 comprises the amino acid sequence set forth as amino acids 47 to 54 of SEQ ID NO: 6, and L-CDR3 comprises the amino acid sequence set forth as amino acids 87 to 95 of SEQ ID NO: 6, wherein the antibody specifically binds poly-γ-D-glutamic acid (γDPGA).