Patent ID: 7217717

Claim:
A compound of the formula wherein Z is C or N; R 1 and R 2 are independently selected from H, lower alkyl, lower alkyl substituted with OR 6 , NR 6 R 7 , heterocycle, and heteroaryl; R 3 and R 4 are each independently selected from H, F, Cl, and Br; R 5 is selected from H, OH, SH, oxo, thione, and C 1 –C 3 alkyl; and R 6 and R 7 are each independently selected from H, and lower alkyl or, alternately NR 6 R 7 together can form a ring having 3 to 7 atoms, said ring optionally including up to three additional heteroatoms and being optionally substituted by one or more lower alkyl; or the pharmaceutically acceptable salts or esters thereof.