Patent ID: 8617514

Claim:
A method of imaging an organ or a tissue in a patient comprising: 1) administering to the patient prior to performing said imaging an antibody- or antibody fragment-targeted cationic immunoliposome complex comprising: a) a cationic liposome, b) an antibody or antibody fragment which binds to a receptor that is differentially expressed on a target cell, and c) an imaging agent, wherein said antibody- or antibody fragment-targeted cationic immunoliposome complex was prepared by: i) preparing a cationic immunoliposome comprising said antibody or antibody fragment and said cationic liposome, wherein said antibody or antibody fragment is not chemically conjugated to said cationic liposome, and ii) mixing said cationic immunoliposome with said imaging agent at a ratio in the range of about 1.0:10 to about 1.0:35 (mg imaging agent:Î¼g liposome); and 2) imaging said organ or said tissue.