Patent ID: 8263616

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt, geometrical isomer, tautomer, optical isomer or N-oxide thereof, wherein: R 1 is selected from: (a) hydrogen, (b) C 1-6 -alkyl, and (c) —NR 4A R 4B ; R 2 is selected from: (a) hydrogen, (b) C 1-6 -alkyl, (c) halo-C 1-6 -alkyl, (d) hydroxy-C 1-6 -alkyl, (e) C 1-6 -alkoxy-C 1-6 -alkyl, (f) halo-C 1-6 -alkoxy-C 1-6 -alkyl, (g) N(R 4A R 4B )—C 1-6 -alkyl, (h) —C(O)NR 4A R 4B , and (i) —C(O)O—C 1-6 -alkyl; R 3 is selected from: (a) C 1-6 -alkyl, (b) halo-C 1-6 -alkyl, (c) hydroxy-C 1-6 -alkyl, (d) C 1-6 -alkoxy-C 1-6 -alkyl, (e) halo-C 1-6 -alkoxy-C 1-6 -alkyl, (f) N(R 4A R 4B )—C 1-6 -alkyl, (g) C 6-10 -aryl-C 1-4 -alkyl, (h) heteroaryl-C 1-4 -alkyl, (i) C 6-10 -aryloxy-C 1-4 -alkyl, (j) heteroaryloxy-C 1-4 -alkyl, (k) C 3-8 -cycloalkyl, (l) C 3-8 -cycloalkyl-C 1-4 -alkyl, (m) heterocyclyl, and (n) heterocyclyl-C 1-4 -alkyl, wherein any aryl or heteroaryl residue is optionally substituted with one more substituents independently selected from halogen, hydroxy, cyano, nitro, CF 3 , C 1-4 -alkyl, C 1-4 -alkoxy and —NR 4A R 4B , and wherein any cycloalkyl or heterocyclyl residue is optionally substituted with one or more substituents independently selected from halogen, hydroxy, C 1-4 -alkyl, C 1-4 -alkoxy and —NR 4A R 4B ; R 4A and R 4B are each independently selected from: (a) hydrogen, (b) C 1-6 -alkyl, and (c) C 1-6 -acyl provided that when R 1 and R 2 are hydrogen, then R 3 is not benzyl.