Patent ID: 6911477

Claim:
A compound of the formula wherein X is (C 1 -C 10 )alkyl or (C 3 -C 10 )cycloalkyl, wherein said (C 3 -C 10 )cycloalkyl may optionally be substituted with from one to three substituents independently selected from the group consisting of —OR 6 , (C 1 -C 4 )alkyl, oxo and a ketal of the formula —O—(CH 2 ) n —O—; n is an integer from one to three; m is an integer from one to three; p is an integer from one to three; Y is N or CH; Z is NR 7 R 8 , (C 3 -C 10 )cycloalkyl, (C 1 -C 10 )alkyl, pyridyl or phenyl; wherein said phenyl or (C 3 -C 10 )cycloalkyl may optionally be substituted with from one to three substituents independently selected from the group consisting of (C 1 -C 6 )alkyl, halo, hydroxy, (C 1 -C 6 )alkoxy, amino, (C 1 -C 6 )-alkylamino, di(C 1 -C 6 )alkylamino and trifluoromethoxy; R 2 is phenyl optionally substituted with from one to three substituents independently selected from the group consisting of (C 1 -C 6 )alkyl, halo, hydroxy, (C 1 -C 6 )alkoxy, amino, (C 1 -C 6 )alkylamino, di(C 1 -C 6 )-alkylamino, —CF 3 , —CN, —COR 6 , NHCOR 6 and trifluoromethoxy; R 3 is phenyl optionally substituted with from one to three substituents independently selected from the group consisting of (C 1 -C 6 )alkyl, halo, hydroxy, (C 1 -C 6 )alkoxy, amino, (C 1 -C 6 )alkylamino, di(C 1 -C 6 )-alkylamino and trifluoromethoxy; R 6 is hydrogen or (C 1 -C 6 )alkyl; and R 7 and R 8 are independently (C 1 -C 10 )alkyl or R 7 and R 8 taken together with the nitrogen atom to which they are attached form a (five to seven)-membered saturated heterocyclic ring in which one of the ring atoms may optionally be replaced with a heteroatom selected from the group consisting of nitrogen, oxygen and sulfur, wherein said (five to seven)-membered saturated heterocyclic ring may optionally be substituted with from one to three substituents independently selected from the group consisting of —OR 6 , (C 1 -C 4 )alkyl, oxo and a ketal of the formula —O—(CH 2 ) p —O—; with the proviso that said substituted heterocycles may not be substituted in the two position by hydroxy or a ketal; and the pharmaceutically acceptable salts thereof.