Patent ID: 8455512

Claim:
A method of inhibiting scar formation, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is a thieno[3,2-c]pyridinyl which may be optionally substituted with one to three substituents each independently selected from the group consisting of: C 1 -C 3 -alkyl, —(C 1 -C 3 -alkyl)-S—(C 1 -C 3 -alkyl), —S—C 1 -C 3 -alkyl, —(C 1 -C 3 -alkyl)-O—(C 1 -C 3 -alkyl), —O—C 1 -C 3 -alkyl, —C(O)O—C 1 -C 3 -alkyl, —C(O)O—H, —C(O)NR 30 R 31 , halo, —CN, and —OH, wherein R 30 and R 31 are each independently selected from the group consisting of: H, C 1 -C 3 alkyl-OH, C 1 -C 3 -alkyl, halo, and —O—C 1 -C 3 -alkyl; R 2 and R 3 are independently selected from the group consisting of hydrogen, C 1 -C 3 -alkyl, —(C 1 -C 3 -alkyl)-S—(C 1 -C 3 -alkyl), —S—C 1 -C 3 -alkyl, —(C 1 -C 3 -alkyl)-O—(C 1 -C 3 -alkyl), —O—C 1 -C 3 -alkyl, —C(O)O—C 1 -C 3 -alkyl, —C(O)O—H, —C(O)NR 2 , —C(O)NH(C 1 -C 3 alkyl), —C(O)N(C 1 -C 3 alkyl) 2 , halo, —CN, —OH, and a C 3 -C 6 -cycloalkyl; and R 4 , R 5 , R 6 , and R 7 are selected from the group consisting of: H, —OH, C 3 -cycloalkyl, C 1 -C 3 -alkyl, —(C 1 -C 3 -alkyl)-S—(C 1 -C 3 -alkyl), —S—C 1 -C 3 -alkyl, —(C 1 -C 3 -alkyl)-O—(C 1 -C 3 -alkyl), —O—C 1 -C 3 -alkyl, —C(O)O—C 1 -C 3 -alkyl, —C(O)O—H, —C(O)NH 2 , —C(O)NH(C 1 -C 3 alkyl), —C(O)NH(O—C 1 -C 3 alkyl), —C(O)N(H)(halo), —C(O)N(C 1 -C 3 alkyl) 2 , —C(O)N(C 1 -C 3 alkyl)(O—C 1 -C 3 alkyl), —C(O)N(C 1 -C 3 alkyl)(halo), —C(O)N(O—C 1 -C 3 alkyl) 2 , —C(O)N(O—C 1 -C 3 alkyl)(halo), —C(O)N(halo) 2 , halo, —CN, and —OH.