Patent ID: 8324202

Claim:
A compound of formula (I) a pharmaceutically acceptable salt thereof or a pure (R) or (S) enantiomer thereof, wherein X is C═O or CH 2 ; R 4 is hydrogen or C 1 -alkyl, and R 1 , R 2 , R 3 , and R 5 are independently hydrogen, (C 1 -C 4 )-alkyl, halogen, NO 2 , (C 1 -C 4 ) alkoxy, (C 1 -C 4 )alkylthio, amino, (C 1 -C 4 )dialkylamino or -A-CONHOH, with A selected from the group consisting of: (C 1 -C 8 )alkylene, (C 2 -C 8 )alkenylene, (C 2 -C 8 )alkynylene, (C 1 -C 8 ) alkylene-NH—CH 2 —, (C 2 -C 8 )alkenylene-NH—CH 2 —, and (C 0 -C 8 ) alkylene-Y—(C 1 -C 8 )alkylene, and Y selected from the group consisting of —NHCO—, —O—, —NH—, and —S—; provided that at least one of R 1 , R 2 , R 3 , and R 5 is -A-CONHOH, and wherein when R 3 is -A-CONHOH, A is not (C 1 )-(C 3 ) alkylene or alkenylene.