Patent ID: 7501407

Claim:
A compound having the structure: wherein, R 13 is a substituted or unsubstituted (C 1 -C 4 )alkyl, branched alkyl or (C 3 -C 7 )cycloalkyl, wherein the substituent is —OH, —OR, —NH 2 , —NR 18 R 19 , —R 20 NHOCR 21 , R 22 R 23 NCO—, carboxyl, carbamoyl (—R 20 NHOCNR 22 R 23 ), carbamate (—R 20 NHOCOR) , or a heterocyclic ring; or a substituted or unsubstituted aryl or heterocyclic ring wherein any substituent, if present, is —OH, —OR, halogen, —NH 2 , or —NHR; wherein R is alkyl, cycloalkyl, aryl, heteroaryl, susbtituted alkyl, aryl, arylalkyl, or heterocyclic; R 14 is substituted or unsubstituted phenyl, wherein the substituent, if present, is halogen, —OH, —NH 2 , —OR, —NHR or a 5-6 membered heterocyclic ring; R 15 is H, or alkyl; R 16 is H, substituted or unsubstituted alkyl or aryl, or R 15 and R 16 are joined to form a heterocyclic ring; X is —CHR 17 , —CR 24 R 25 , O or —NR; R 17 is H, substituted or unsubstituted alkyl, aryl, arylalkyl, heterocyclic, heterocyclic alkyl, —OH, —OR, —NH 2 , —NR 18 R 19 , R 22 R 23 NCO —, carboxyl, carbamoyl (—R 20 NHOCNR 22 R 23 ), carbamate (—R 20 NHOCOR), or (C 3 -C 7 ) cycloalkyl; R 18 and R 19 are each independently hydrogen, substituted or unsubstituted alkyl or aryl or R 18 NR 19 together form a heterocyclic ring of between 4 and 8 members; R 20 and R 21 are each independently a substituted or unsubstituted alkyl, aryl, or alkylaryl moiety; R 22 and R 23 are each independently hydrogen, substituted or unsubstituted alkyl, aryl or alkylaryl, or R 22 NR 23 together form a heterocyclic ring of between 4 and 8 members; R 24 and R 25 are each independently hydrogen, substituted or unsubstituted alkyl, cycloalkyl, aryl, heterocyclic or R 24 and R 25 together form a 3-7 membered ring system or a dioxalane or dioxane ring system; and p is 0, 1 or 2.