Patent ID: 6974591

Claim:
A method for producing a controlled-release pharmaceutical preparation with a particle-containing coating comprising the steps of: a) preparing a drug-containing solid core; b) suspending a pore-forming agent having a balanced solubility in an aqueous dispersion of a film-forming, essentially water insoluble polymer in order to form a coating suspension having a predetermined amount of solid particles of the pore-forming agent suspended therein c) coating the solid core with the obtained suspension; and d) drying the coating; wherein the pore-forming agent is soluble in body fluids; wherein the mean particle size of the pore-forming agent is 0.5-100 μm; and wherein the amount of the pore-forming agent is 40-95% by weight of the total weight of the dry coating and; wherein the coating provides good mechanical strength requiring a force of from 18N to 27N to break, compared to a force below 1N.