Patent ID: 8178122

Claim:
An endo-osseous implant comprised of biocompatible metallic materials, characterized in that said implant comprises a coating comprised of nanocrystalline material comprising nanoparticles of formula (I): AO x -(L-Me n+ ) i , (I) where AO x represents TiO 2 or ZrO 2 ; Me n+ is a metallic ion having antibacterial activity, with n=1 or 2; L is a bifunctional organic molecule which can simultaneously bind to the metal oxide and to the metallic ion Me n+ ; and i is the number of L-Me n+ groups bound to one nanoparticle of AO x , wherein L is 4-mercaptophenylboronic acid wherein AO x is functionalized with 4-mercapotophenylboronic acid and 4-mercaptophenylboronic acid binds Me n+ .