Patent ID: 8075872

Claim:
An abuse-proofed dosage form thermoformed by extrusion without discoloration and having a breaking strength of at least 500 N, which contains a mixture of: i) one or more active ingredients with abuse potential (A) selected from the group consisting of opioids, ii) optionally physiologically acceptable auxiliary substances (B), iii) from 30% by weight to 99.9% by weight of at least one polyalkylene oxide (C), having a molecular weight of from about 4,000,000 g/mol up to 15,000,000 g/mol, iv) optionally at least one wax (D), and v) a further material selected from the group consisting of hydroxypropylmethylcellulose, hydroxypropylcellulose and hydroxymethylcellulose, wherein said extrusion takes place in an extruder at a temperature of from at least the softening point of the polyalkylene oxide up to a temperature of below 180° C., and wherein component (C) and/or the optionally present component (D) serve as a controlled release matrix material in which the active ingredient with abuse potential (A) is embedded and said dosage form not being in multiparticulate form.