Patent ID: 8288404

Claim:
A compound of Formula (I): or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein: X is selected from the group consisting of: O, S, CH 2 , CH(C 1-4 alkyl), C(C 1-4 alkyl) 2 , CH(C 1-4 alkoxy-phenyl), and C(O); ring A is phenyl substituted with 0-2 R 5 , pyridinyl substituted with 0-2 R 5 , or pyrimidinyl substituted with 0-2 R 5 ; R 1 is â€”(CH 2 ) n -phenyl substituted with 0-3 R 2 , â€”(CH 2 ) n -naphthyl substituted with 0-3 R 2 , or â€”(CH 2 ) n -5- to 6-membered heteroaryl containing carbon atoms and 1-4 heteroatoms selected from the group consisting of N, O, and S(O) p ; wherein said heteroaryl is substituted with 0-3 R 2 ; R 2 , at each occurrence, is independently selected from the group consisting of: halo, CF 3 , CN, NO 2 , OCF 3 , SCF 3 , C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylthio, NH 2 , NH(C 1-4 alkyl), N(C 1-4 alkyl) 2 , â€”(CH 2 ) n â€”C 3-10 carbocycle, â€”(CH 2 ) n â€”Oâ€”C 3-10 carbocycle, and â€”(CH 2 ) n -3- to 10-membered heterocycle containing carbon atoms and 1-4 heteroatoms selected from the group consisting of N, O, and S(O) p ; wherein said carbocycle and heterocycle are substituted with 0-3 R 6 ; R 3 and R 4 , at each occurrence, are independently selected from the group consisting of: H, OH, halo, CF 3 , C 1-4 alkyl, and C 1-4 alkoxy; R 5 , at each occurrence, is independently selected from the group consisting of: halo and C 1-4 alkyl; R 6 , at each occurrence, is independently selected from the group consisting of: halo, CF 3 , C 1-4 alkyl, and C 1-4 alkoxy; n, at each occurrence, is independently 0, 1, 2 or 3; and p, at each occurrence, is independently 0, 1 or 2.