Patent ID: 8513433

Claim:
A compound of Formula (I): wherein R 1 is one or more H, hydroxy, halogen, cyano, OR 4 , nitro, NH 2 , NR 4 R 5 , NR 4 COR 5 , NR 4 SO 2 R 5 , CONR 4 R 5 , COOR 4 , SO 2 R 4 , alkynyl, optionally substituted aliphatic, alicyclic, heteroaliphatic, or heterocyclic; R 2 is H, optionally substituted alkyl or cycloalkyl; R 3 is H, COR 4 , CONR 4 R 5 , COOR 4 , SO 2 R 4 , optionally substituted alkyl, alkenyl, alkynyl, cyclolalkyl, heterocycloalkyl, aryl or heteroaryl; R 4 and R 5 are independently selected from the group consisting of H, OH, NH 2 , alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; A and B joined together form a bicyclic ring wherein: A is nonaromatic 4, 5, 6, 7 or 8-membered ring that contains 1 or 2 nitrogen atoms and optionally one sulfur or oxygen atom, where in the nonaromatic ring is optionally substituted with 1, 2 or 3 substituents selected from the group consisting of hydroxy, halogen, cyano, OR 4 , nitro, NH 2 , NR 4 R 5 , NR 4 COR 5 , NR 4 SO 2 R 4 , CONR 4 R 5 , COOR 4 , SO 2 R 4 , alkyl, alkenyl, alkynyl, alkoxyalkyl, alkoxycarbonylalkyl, cycloalkyl, cycloalkylalkyl, haloalkyl, heterocycle, heterocycloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl and oxo; and B is aryl or heteroaryl that is optionally substituted with 1, 2 or 3 substituents selected from the group consisting of hydroxy, halogen, cyano, OR 4 , nitro, NH 2 , NR 4 R 5 , NR 4 COR 5 , NR 4 SO 2 R 5 , CONR 4 R 5 , COOR 4 , SO 2 R 4 , alkyl, alkenyl, alkynyl, alkoxyalkyl, alkoxycarbonylalkyl, cycloalkyl, cycloalkylalkyl, haloalkyl, heterocycle, heterocycloalkyl, aryl, arylalkyl, heteroaryl, and heteroarylalkyl.