Patent ID: 6943253

Claim:
A 6-phenylpyrrolopyrimidinedione derivative of formula (I) wherein: —X—C—Y— represents or —X—C—Y— represents R 1 , R 2 and R 3 each independently represent: a hydrogen atom; an alkyl group which is unsubstituted or substituted by one or more hydroxy, alkoxy, alkylthio, amino, mono- or di-alkylamino, hydroxycarbonyl, alkoxycarbonyl, acylamnino, carbamoyl or alkylcarbanioyl groups; or a group of formula —(CH 2 ) n —R 7 wherein n is an integer from 0 to 4 and R 7 represents: a cycloalkyl group; a phenyl group which may be unsubstituted or substituted by one or more halogen atoms or alkyl, hydroxy, alkylenedioxy, alkoxy, amino, mono- or di-alkylamino, nitro, cyano or trifluoromethyl groups; or a 3 to 7-membered ring comprising from 1 to 4 heteroatoms selected from nitrogen, oxygen and sulphur. which ring may be unsubstituted or substituted by one or more halogen atoms or hydroxy, phenyl, alkoxycarbonyl, amino, mono-alkylamino, di-alkylarnino or hydroxycarbonyl groups or one or more alkyl groups which may in turn be unsubstituted or substituted by one or more halogen atoms or hydroxy, alkoxy, hydroxyalkoxy, phenyl, alkoxycarbonyl, amino, mono- or di-alkylamino or hydroxycarbonyl groups, either R 4 and R 5 together with the nitrogen atom to which they are attached form a 3 to 7-membered ring comprising a total of from 1 to 4 heteroatoms selected from nitrogen, oxygen and sulphur, which ring may be unsubstituted or substituted by one or two substituents selected from (a) halogen atoms and hydroxy, oxoalkyl, carbamoyl, hydroxycarbonyl, alkoxycarbonyl, amino, mono- and di-alkylamino groups and (b) alkyl, alkenyl and divalent alkylene groups which may in turn be unsubstituted or substituted by one or more hydroxy, alkoxy, hydroxyalkoxy, amino or mono- or di-alkylamino groups, or R 4 and R 5 independently represent a hydrogen atom or an alkyl group which may be unsubstituted or substituted by one or more hydroxy, alkoxy, alkylthio, amino, mono- or di-alkylaniino groups, or R 4 represents hydrogen or an alkyl group and R 5 represents a group of formula —(CH 2 ) n —R 7 as defined above, R 6 represents a hydrogen or halogen atom, or a nitro or alkoxycarbonyl group, or an alkyl group which is unsubstituted or substituted by one or more hydroxy, alkoxy, alkylthio, amino, mono- or di-alkylamino, hydroxycarbonyl, alkoxycarbonyl, acylamino, carbamoyl or alkylcarbamoyl groups, or an N-oxide or a pharmaceutically acceptable salt thereof.