Patent ID: RE39530

Claim:
A 3-Amino-3-arylpropan-1-ol 3 - amino - 3 - arylpropan - 1 - ol compound corresponding to formula I wherein R 1 and R 2 each independently denote C 1-6 -alkyl, or R 1 and R 2 together form a (CH 2 ) 2-6 ring, which can also be benzo-fused or phenyl-substituted; R 3 denotes H or methyl; R 4 and R 5 each independently denote C 1-6 -alkyl, C 3-6 -cycloalkyl, phenyl, benzyl or phenethyl, or R 4 and R 5 together form a (CH 2 ) 3-6 or CH 2 CH 2 OCH 2 CH 2 ring; A denotes a substituted or unsubstituted aryl radical, which optionally contains heteroatoms in the ring system; X denotes a substituted benzyl group corresponding to formula XI or a substituted benzoyl group corresponding to formula XII wherein R 12 to R 14 each independently denote H, F, Cl, Br, CHF 2 , CF 3 , OR 11 , SR 11 OR 15 , SR 15 , OCF 3 , SO 2 CH 3 , SO 2 CF 3 , C 1-6 -alkyl, phenyl, CN, COOR 11 COOR 15 or NO 2 , where R 11 R 15 denotes H, C 1-6 -alkyl, phenyl, benzyl, or phenethyl; and diastereomers or enantiomers thereof, or a salt thereof with a physiologically acceptable acid , with the proviso that if R 1 and R 2 together form a ( CH 2 ) 4 ring, R 3 is H, A is a substituted phenyl group corresponding to formula XIII in which one of R 6 to R 10 is OH and the remainder of R 6 to R 10 are H, and X is a benzyl group corresponding to formula XI in which R 12 to R 14 are all H, then R 4 and R 5 are not both C 1-2 - alkyl .