Patent ID: 7258735

Claim:
A method of making a calcium phosphate cement (CPC) paste having either a desired setting time or a desired working time, the method comprising: contacting a calcium phosphate powder comprising one or more calcium phosphates with a wetting solution to form a mixture, the calcium phosphate powder having a Ca/P molar ratio in the range of 0.5-2.5; drying the mixture by heating the mixture at a temperature of up to about 1000° C.; forming calcium phosphate cement particles from the heated mixture; and contacting the calcium phosphate cement particles with a sufficient volume of a setting solution to form an injectable paste; wherein one or more of the calcium phosphates, the wetting solution, the setting solution, and the temperature that the mixture is heated to is selected such that the injectable paste has either a setting time in the range of 2.5 min to 35 min or a working time in the range of 1.5 min to 31 min.