Patent ID: 7629318

Claim:
A compound having a structure of Formula II: wherein, as valence and stability permit, A is absent or represents a sequence of from one to four amino acid or amino acid analog residues; B represents a sequence of from two to eight amino acid or amino acid analog residues and wherein the N-terminal residues of said sequence are Tic-Nle; W represents OR 7 or NR 8 R 9 , V is C═O; X is absent or represents O, S, or NR; R, independently for each occurrence, represents H or lower alkyl; R 1 represents a substituted or unsubstituted alkyl, heteroalkyl, alkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, cycloalkyl, cycloalkylalkyl, hetaocyclyl, or heterocyclylalkyl moiety; R 2 represents a substituted or unsubstituted alkyl, heteroalkyl, alkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, cycloalkyl, cycloalkylalkyl, hetaocyclyl, or heterocyclylalkyl moiety, or R 2 and R, taken together, form a ring having from 5 to 7 members, optionally being substituted with from 1 to 5 substituents and/or forming a polycyclic structure with one or more other rings; i represents an integer from 0-1; j is 1; k is 2; and R 6 is absent or represents from 1-4 substituents on the nitrogen-containing ring to which it is attached, selected from substituted or unsubstituted lower alkyl, haloalkyl, halogen, hydroxyl, and amino. R 7 , R 8 and R 9 independently represent substituents selected from H and substituted or unsubstituted alkyl, heteroalkyl, aryl, aralkyl, heteroaralkyl, heteroaryl, cycloalkyl, cycloalkylalkyl, hetaocyclyl, and heterocyclylalkyl, or where R 8 and R 9, taken together, form a ring having from 5 to 7 members, optionally being substituted with from 1 to 5 substituents and/or forming a polycyclic structure with one or more other rings.