Patent ID: 8916174

Claim:
A DNA composition capable of stimulating an immune response comprising: a promoter sequence derived from Caprine Arthritis Encephalitis Goat Lentivirus (CAEV) operably linked to a coding sequence, wherein the coding sequence encodes a gag gene, a pro gene, a vpx gene, a vpr gene, a vpu gene, a nef gene, a tat gene, an env gene, and a rev gene, wherein the genes are of an immunodeficiency viral genome selected from the group consisting of Human Immunodeficiency Virus (HIV), Simian Immunodeficiency Virus (SIV), and combinations thereof, wherein the coding sequence is operably linked to a polyadenylation sequence, and wherein the DNA composition does not include functional reverse transcriptase (rt), integrase (int), and viral infectivity factor (vif).