Patent ID: 7910117

Claim:
A method of eliciting in a subject an antibody that binds the lipopolysaccharide (LPS) inner core of immunotypes L2 and L4 of galE mutants of Neisseria meningitidis comprising administering to said subject an immunogenic composition comprising the LPS inner core of a galE mutant of a strain of Neisseria meningitidis immunotype L4, wherein the LPS inner core of the galE mutant has the formula: and comprises an LPS inner core epitope, wherein the phosphoethanolamine (PEtn) moiety is linked to the 6 position of the HepII of the LPS inner core, and wherein said epitope is specifically recognized by the monoclonal antibody A4 produced by the hybridoma deposited with the accession number IDAC 260900-2.