Patent ID: 7632484

Claim:
A reagent for preparing a scintigraphic imaging agent comprising a targeting ligand covalently linked to ethylenedicysteine (EC), wherein the targeting ligand is an anticancer agent that is methotrexate, doxorubicin, tamoxifen, paclitaxel, topotecan, LHRH, mitomycin C, etoposide tomudex, podophyllotoxin, mitoxantrone, camptothecin, colchicine, endostatin, fludarabin, gemcitabine, or tomudex; an agent that mimics glucose; a folate receptor targeting ligand; or a tumor apoptotic cell targeting ligand or a tumor hypoxia targeting ligand that is annexin V, colchicine, nitroimidazole, mitomycin, or metronidazole.