Patent ID: 7951824

Claim:
A compound of formula (I) wherein R 1 is a 5-member ring of formula (II): R 2 is C 1 -C 7 -alkyl; R 3 is aryl or is heteroaryl selected from the group consisting of imidazolyl, oxazolyl, thiazolyl, pyrazinyl, pyrrolyl, pyridinyl, pyrimidinyl, indolyl, isoquinolinyl, carbazol-9-yl, furanyl, benzofuranyl, benzo[1,2,3]thiadiazolyl, benzo[b]thiophenyl, 9H-thioxanthenyl, and thieno[2,3-c]pyridinyl each of which is optionally substituted by one or more substituents selected from the group consisting of CN, Cl, F, Br, CF 3 , CHF 2 , C 1 -C 7 alkyl, —O—C 1 -C 7 -alkyl, —(CO)—R b , —(CH 2 ) m —R c , —NH—(CO)—C 1 -C 7 -alkyl, —O—CH 2 F, —O—CHF 2 , —S(O) 2 —R d , and —NR g R h or wherein the heteroaryl is optionally substituted by C 1 -C 7 -alkyl; R 5 is H, —OH, Cl, F, Br, CN, CF 3 , CHF 2 , C 1 -C 7 -alkyl, —C 3 -C 6 -cycloalkyl, —O—(CO)—C 1 -C 7 -alkyl, —(CH 2 ) m —R e , or —(CO)—NR i R j ; R 7 is H, Cl, F, CN or C 1 -C 7 -alkyl; R b is C 1 -C 7 -alkyl, NR g R h or —O—C 1 -C 7 -alkyl; R c is —OH, —NR g R h or NH—(CO)—O—C 1 -C 7 -alkyl; R d is C 1 -C 7 -alkyl, —NR g R h , —NH—C 1 -C 7 -alkyl or —N-di(C 1 -C 7 -alkyl); R e is —OH, CH 2 F, CHF 2 , CF 3 , CN, C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy, —(CO)—NR i R j or —O—(CO)—C 1 -C 7 -alkyl; R g and R h are each independently H, C 1 -C 7 -alkyl, C 3 -C 6 -cycloalkyl, C 3 -C 8 -alkenyl, phenyl, benzyl, or —(CO)—R i or R g and R h can also, together with the nitrogen atom to which they are attached, form a 5- to 7-membered heterocyclic or heteroaryl ring optionally substituted with 1 or 2 OH; R i and R j are each independently H or C 1 -C 7 alkyl; R′ is —NR g R h , —NH—C 1 -C 7 -alkyl, C 1 -C 7 -alkyl, or C 1 -C 7 -alkoxy; m is 1 to 4; or a pharmaceutically acceptable salt thereof.