Patent ID: 7132445

Claim:
A compound of the formula: and the pharmaceutically acceptable salts and solvates thereof, wherein: A is selected from the group consisting of: wherein said A group is substituted with 1 to 6 substituents each independently selected from the group consisting of: unsubstituted alkyl; wherein said A group is substituted with 1 to 6 substituents each independently selected from the group consisting of: unsubstituted alkyl; wherein one or both rings of said A group is substituted with 1 to 6 substituents each independently selected from the group consisting of: unsubstituted alkyl; wherein one or both rings of said A group is substituted with 1 to 6 substituents each independently selected from the group consisting of: unsubstituted alkyl; B is: wherein R 3 is selected from the group consisting of: —C(O)NR 13 R 14 , n is 0; R 2 is selected from the group consisting of: hydrogen, OH, —C(O)OH, —SH, —SO 2 NR 13 R 14 , —NHC(O)R 13 , —NHSO 2 NR 13 R 14 , —NHSO 2 R 13 , —NR 13 R 14 , —C(O)NR 13 R 14 , —C(O)NHOR 13 , —C(O)NR 13 OH, —S(O 2 )OH, —OC(O)R 13 ; R 4 is independently selected from the group consisting of: hydrogen, cyano, halogen, alkyl, alkoxy, —OH, —CF 3 , —OCF 3 , —NO 2 , —C(O)R 13 , —C(O)OR 13 , —C(O)NHR 17 , —C(O)NR 13 R 14 , —SO (t) NR 13 R 14 , —SO (t) R 13 , —C(O)NR 13 OR 14 , and unsubstituted or substituted aryl, wherein there are 1 to 6 substituents on said substituted aryl group and each substituent is independently selected from the group consisting of: R 9 groups; each R 5 and R 6 are the same or different and are independently selected from the group consisting of hydrogen, halogen, alkyl, alkoxy, —CF 3 , —OCF 3 , —NO 2 , —C(O)R 13 , —C(O)OR 13 , —C(O)NR 13 R 14 , —SO (t) NR 13 R 14 , —C(O)NR 13 OR 14 , cyano, and unsubstituted aryl; each R 7 and R 8 is independently selected from the group consisting of: H, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl, alkynyl and alkenyl; and wherein there are one or more substituents on said substituted R 7 and R 8 groups, wherein each substituent is independently selected from the group consisting of: a) halogen, b) —CF 3 , c) —COR 13 , d) —OR 13 , e) —NR 13 R 14 , f) —NO 2 , g) —CN, h) —SO 2 OR 13 , i) —CO 2 R 13 , j) —C(O)NR 13 R 14 , k) —NR 13 C(O)R 14 , and l) —NR 13 CO 2 R 14 ; each R 9 is independently selected from the group consisting of: —R 13 ; each R 13 and R 14 is independently selected from the group consisting of: H and unsubstituted alkyl; each R 15 is independently selected from the group consisting of: H, alkyl, aryl, arylalkyl, cycloalkyl and heteroaryl; R 17 is selected from the group consisting of: —SO 2 alkyl, —SO 2 aryl, —SO 2 cycloalkyl, and —SO 2 heteroaryl; R 30 is selected from the group consisting of: alkyl, cycloalkyl, —CN, —NO 2 , or —SO 2 R 15 provided that R 15 is not H; and t is 0, 1 or 2.