Patent ID: 8772295

Claim:
A compound of Formula Ic: wherein X n and X y are each independently H, C, N, O, or a halogen; where n is the integer 0 or 1; where y is the integer 0 or 1; wherein (dotted line) is an optional bond; wherein z is the integer 0, 1, or 2, with the provisos that: 1) z =0 when X =halogen and is not a bond; and 2) when z =0, X =O, is not a bond, and one or more oxygen atoms (X) are present, oxygen is attached to a methyl group; where Ar is selected from a substituted phenyl and a substituted thiophene group; wherein the phenyl group is substituted with one or more C 1 to C 7 alkyl and an isoxazolyl group, and the thiophene group is substituted with C(O)NH 2 ; or a pro-drug, a pharmaceutically acceptable salt, or a derivative thereof.