Patent ID: 7326698

Claim:
A compound having a formula: or a pharmaceutically acceptable salt or a C 1-6 alkyl ester prodrug thereof; wherein a dashed line represents the presence or absence of a double bond or a triple bond; A is —(CH 2 ) 6 —, cis —CH 2 CH═CH—(CH 2 ) 3 —, or —CH 2 C≡C—(CH 2 ) 3 —, wherein 1 or 2 carbon atoms may be substituted with S or O; X is selected from the group consisting of CO 2 H, CONHR 2 , CONR 2 , CON(OR)R, CON(CH 2 CH 2 OH) 2 , CONH(CH 2 CH 2 OH), CH 2 OH, P(O)(OH) 2 , CONHSO 2 R, SO 2 NR 2 , SO 2 NHR, and J is C═O, CHOH, or CH 2 CHOH; R is independently H, C 1 -C 6 alkyl, phenyl, or biphenyl; and E is C 3 -C 6 alkyl, C 4 -C 10 cycloalkyl, phenyl or napthyl having from 0 to 2 substituents, or thienyl, furyl, pyridinyl, benzothienyl, or benzofuryl having from 0 to 2 substituents, wherein said substituents are independently selected from: a hydrocarbon moiety having from 1 to 4 carbon atoms, CO 2 H, alkoxy having from 1 to 3 carbon atoms, CN, NO 2 , CF 3 , F, Cl, Br, I, and SO 3 H.