Patent ID: 8920839

Claim:
A press-coated orally-disintegrating tablet with an inner core which is a powder/granular material with poor formability and an outer layer surrounding the inner core wherein the inner core has a thickness in the range of 20 to 80% per that of the whole tablet, and the outer layer consisting of (a) microcrystalline cellulose, (b) one or more inorganic excipients selected from the group consisting of calcium hydrogen phosphate, calcium hydrogen phosphate anhydrate, and monobasic calcium phosphate, (c) one or more particular ingredients selected from the group consisting of crospovidone, starches and low substituted hydroxypropylcellulose, and (d) one or more additional formulation ingredients, wherein the one or more additional formulation ingredients (d) are one or two selected from the group consisting of fillers, disintegrants, binders, sweetening agents, taste correctives/odor correctives, stabilizer, surfactant, fluidizing agents, antistatic agents, coating agents, lubricants, colorants, and flavors, wherein the microcrystalline cellulose (a) is contained in the range of 5 to 80 wt % per 100 wt % of the outer layer, the total content of the inorganic excipient (b) is contained in the range of 30 to 60 wt % per 100 wt % of the outer layer, the total content of the one or more particular ingredients (c) is in the range of 1 to 40 wt % per 100 wt % of the outer layer, and the one or more additional formulation ingredients are contained in the range of 0.01 to 25 wt % per 100 wt % of the outer layer, wherein the absolute hardness of the press-coated orally-disintegrating tablet is 1.5 N/mm 2 or more.