Patent ID: 7378417

Claim:
A compound according to formula (I) wherein p is 0 or 1; R 1 and R 2 are each independently H; halogen; lower alkyl optionally substituted by lower alkoxy; lower alkoxy optionally substituted by one or more halogen; or CF 3 ; R 3 is lower alkyl; hydroxy-lower alkyl; or NR a R b ; R a and R b are each independently selected from the group consisting of: H; lower alkyl optionally substituted by one or more hydroxy, fluoro, cycloalkyl, aryl, heteroaryl or NR c R d wherein R c and R d are independently selected from H or lower alkyl; cycloalkyl; aryl; and heteroaryl; or R a and R b together with the nitrogen atom to which they are attached form an optionally substituted 5 or 6 membered heterocyclic ring; R 4 is H, Cl, lower alkoxy, cycloalkyl or straight lower alkyl which is optionally substituted by one or more F; and R 5 is H; halogen or lower alkyl; or a pharmaceutically acceptable salt thereof; with the exception of the compounds: pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(difluoromethyl)-5-(4-methylphenyl)-N-[3-(4-morpholinylsulfonyl)phenyl]; pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(difluoromethyl)-N-[3-(4-morpholinylsulfonyl)phenyl]-5-phenyl; and pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[3-(4-morpholinylsulphonyl)phenyl].