Patent ID: 7973182

Claim:
A process for the preparation of an salt of a carboxylic acid with an aminoalcohol of formula: wherein R 1 is selected from the group consisting of 2-thienyl, 2-furanyl, phenyl, 2-thienyl substituted with at least one halogen and/or at least one C 1-4 -alkyl or C 1-4 -alkoxy, 2-furanyl substituted with at least one halogen and/or at least one C 1-4 -alkyl or C 1-4 -alkoxy, and phenyl substituted with at least one halogen and/or at least one C 1-4 -alkyl or C 1-4 -alkoxy, and wherein R 2 is selected from the group consisting of C 1-4 -alkyl, phenyl, C 1-4 -alkyl substituted with at least one halogen and/or at least one C 1-4 -alkyl or C 1-4 -alkoxy, and phenyl substituted with at least one halogen and/or at least one C 1-4 -alkyl or C 1-4 -alkoxy, comprising asymmetrically hydrogenating a salt of a carboxylic acid with an aminoketone of formula: wherein R 1 and R 2 are as defined above, in the presence of a catalytic amount of a catalyst comprising a transition metal complex of a diphosphine ligand.