Patent ID: 7282515

Claim:
A method for the treatment of pain in a subject in need thereof, comprising administering to the subject a compound of general Formula II: where y 2 represents S, NH or O; X 2 represents S; R 4 and R 5 independently of each other represent hydrogen, hydroxy, formyl, carboxy, halogen, mercapto, sulfonyl, amino, amido or a —R 10 optionally substituted with a Q 4 group or jointly form an oxo or thioxo group; R 6 is hydrogen, hydroxy, amino or a —R 11 optionally substituted with a Q 5 group; Z 2 is a 4-10 membered saturated or unsaturated hydrocarbon ring optionally substituted at any ring atom with one or several substituents independently selected from hydrogen, hydroxy, formyl, carboxy, halogen, mercapto, sulfonyl, amino, amido or a—R 12 optionally substituted with a Q 6 group; R 10 , R 11 and R 12 , independently of one another, represent C 1-5 alkyl, C 3 -C 6 cycloalkyl, C 2-5 alkenyl, C 2-5 alkinyl, C 1-5 alkoxy, C 1-5 alkylcarbonyl, C 1-5 alkoxycarbonyl, C 1-5 alkylthio, C 1-5 alkylamino, C 1-5 s alkylsulfinyl, C 1-5 alkylsulfonyl, C 1-5 alkylamino-C 1-5 alkyl, C 1-5 alkylthio-C 1-5 alkyl or C 1-5 alkoxy-C 1-5 alkyl; Q 4 , Q 5 and Q 6 , independently of one another, are hydrogen, hydroxy, formyl, carboxy, halogen, mercapto, sulfonyl, amino or amido, or free base, tautomer, enantiomer, racemate thereof, or a pharmaceutically acceptable salt of any of the foregoing.