Patent ID: 8426442

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt thereof wherein: A represents a chemical moiety having formula (II): X and Y are independently selected from the group consisting of CH 2 , CH(R 5 ) and C(R 5 )(R 6 ); R 1 is selected from the group consisting of optionally substituted arylalkyl and optionally substituted heteroarylalkyl; R 2 is selected from the group consisting of optionally substituted aryl, optionally substituted heteroaryl, and NR 7 R 8 ; R 3 is selected from the group consisting of hydrogen, halogen, hydroxyl, alkoxy, aryloxy, optionally substituted alkyl, optionally substituted amino, optionally substituted amino sulfonyl, and cyano; R 4 is selected from the group consisting of optionally substituted alkyl, wherein the alkyl substituents are selected from the group consisting of cyano, halogen, hydroxyl, alkylamino, dialkylamino, amido, alkylamido, dialkylamido, alkanoyl, alkoxy, sulfonamido, nitro, aryl, and heteroaryl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, (C═O)R 23 , optionally substituted sulfonyl, optionally substituted sulfamoyl, optionally substituted aryl, optionally substituted arylalkyl, and optionally substituted heteroaryl; R 5 and R 6 for each occurrence is optionally substituted alkyl; R 7 and R 8 are the same or different and each represents hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted arylalkyl, optionally substituted aryl or optionally substituted heteroaryl; R 23 is optionally substituted alkyl, wherein the alkyl substituents are selected from the group consisting of cyano, halogen, hydroxyl, alkylamino, dialkylamino, amido, alkylamido, dialkylamido, alkanoyl, alkoxy sulfonamido, nitro, and heteroaryl; optionally substituted aryl, wherein the aryl substituents are selected from the group consisting of cyano, halogen, hydroxyl, nitro, trifluoromethyl, alkyl, alkylthio, alkoxy, amino, alkylamino, dialkylamino, alkanoyl, amido, N-alkylamido, NN-dialkylamino, sulfonamido, aryl, and heteroaryl; optionally substituted heteroaryl; or optionally substituted alkylheteroaryl; n=0, 1, 2 or 3; o=0, 1 or 2; with the proviso that when o=0, then n is 1, 2 or 3 and when o=1, then n is 1 or 2.