Patent ID: 7256206

Claim:
A compound of Formula I: wherein: Y is —CH 2 CH 2 —, —CH 2 CH(OH)—, —CH(OH)CH 2 —, —C(O)CH 2 —, —CH 2 C(O)—, —CH═CH— or 1,2-cyclopropylene; X is arylene or C 5-6 heteroarylene optionally substituted by one to three substituents selected from halo, C 1-10 alkyl and halo-substituted C 1-6 alkyl; R 1 is a group of formula (a), (b), (c), (d), (e) or (f): in which n is 0, 1, 2, 3, 4 or 5; m is 0, 1 or 2; R 6 is C 1-10 alkyl, cycloalkyl, C 1-10 alkoxy, C 2-10 alkenyl, C 2-10 alkynyl, C 1-10 alkylthio, C 1-10 alkylsulfonyl, C 1-10 alkylsulfinyl or halo-substituted-C 1-10 alkyl; in each of which any aliphatic part of the group can be straight chain or branched and can be optionally substituted by up to three hydroxy, cycloalkyl, or C 1-4 alkoxy groups and optionally interrupted by a double or triple bond or one or more C(O), NR 12 , S, S(O), S(O) 2 or O groups, R 7 is aryl or C 5-6 heteroaryl optionally substituted by aryl, C 5-6 heteroaryl or C 3-8 heterocycloalkyl wherein any aryl, heteroaryl or heterocycloalkyl group of R 7 can be optionally substituted by one to three substituents selected from halogen, C 1-10 alkyl, C 1-10 alkoxy, halo-substituted-C 1-10 alkyl and halo-substituted-C 1-10 alkoxy; R 2 is hydrogen; C 1-4 alkyl optionally substituted with one or more halogens; C 2-6 alkenyl, C 2-6 alkynyl, or cycloalkyl optionally substituted by halogen; or C 1-4 alkyl optionally substituted on the terminal C atom by OH or a residue of formula (g): in which Z is O, S, (CH 2 ) 1-2 , CF 2 or NR 11 where R 11 is H, (C 1-4 )alkyl or halo substituted (C 1-4 )alkyl; and R 9 and R 10 , independently, are H, OH, (C 1-4 )alkyl optionally substituted by one to three halo groups, or (C 1-4 )alkoxy; with the proviso that R 9 and R 10 are not both hydrogen; R 3 and R 4 , independently, are H or C 1-4 alkyl optionally substituted by halogen or acyl; and R 5 is —OH, —Oacyl, —NHacyl, or a residue of formula (g) as defined above; or a salt thereof.