Patent ID: 7053215

Claim:
A compound having the formula: or a pharmaceutically acceptable salt, racemate, diastereomer or geometric isomer thereof wherein A 4 is C; X is —C(O)—; R 1 and R 2 are each members independently selected from the group consisting of H, and (C1–C4) alkyl; R 3 is selected from the group consisting of substituted or unsubstituted pyridyl and substituted or unsubstituted imidazolyl; R 4 is a member selected from the group consisting of (C 1 –C 20 )alkyl, (C 2 –C 20 )heteroalkyl, heteroaryl, aryl, heteroaryl(C 1 –C 6 )alkyl, heteroaryl(C 2 –C 6 )heteroalkyl, aryl(C 1 –C 6 )alkyl and aryl(C 2 –C 6 )heteroalkyl; R 14 is substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl; Q is —C(O)—; L is (C 1 –C 8 )alkylene; the subscript n is an integer of from 0 to 4; and each R a is independently selected from the group consisting of halogen, —OR′, —OC(O)R′, —NR′R″, —SR′, —R′, —CN, —NO 2 , —CO 2 R′, —CONR′R″, —C(O)R′, —OC(O)NR′R″, —NR″C(O)R′, —NR″C(O) 2 R′, —NR′—C(O)NR″R′″, —NH—C(NH 2 )═NH, —NR′C(NH 2 )═NH, —NH—C(NH 2 )═NR′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —N 3 , —CH(Ph) 2 , perfluoro(C 1 –C 4 )alkoxy, and perfluoro(C 1 –C 4 )alkyl, wherein R′, R″ and R′″ are each independently selected from the group consisting of H, (C 1 –C 8 )alkyl, (C 2 –C 8 )heteroalkyl, unsubstituted aryl, unsubstituted heteroaryl, (unsubstituted aryl)-(C 1 –C 4 )alkyl, and (unsubstituted aryl)oxy-(C 1 –C 4 )alkyl.