Patent ID: 6855715

Claim:
A compound of formula (I) where R 2 represents (i) phenyl optionally being substituted in the 3 and/or 4 position by halo, nitro, thiol, haloalkoxy, hydrazido, alkylhydrazido, amino, haloalkyl, alkylthio, alkenyl, alkynyl, acylamino, tri or difluoromethoxy, carboxy, acyloxy, MeSO 2 — or R 1 , and optionally substituted at the 6 position by amino, hydroxy, halo, alkyl, carboxy, alkoxycarbonyl, cyano, amido, aminoalkyl, alkoxy or alkylthio; or (ii) naphth-2-yl optionally substituted at the 6 or 7 position by halo, haloalkoxy, haloalkyl, cyano, nitro, amino, hydrazido, alkylthio, alkenyl, alkynyl or R 1j and optionally substituted at the 3 position by amino, hydroxy, halo, alkyl, carboxy, cyano, amido, aminoalkyl, alkoxy or alkylthio; —X—X— is CONH; R 1j represents hydrogen or hydroxyl, alkoxy, alkyl, aminoalkyl, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, alkylaminocarbonyl, alkoxycarbonylamino, acyloxymethoxycarbonyl or alkylamino optionally substituted by hydroxy, alkylamino, alkoxy, oxo, aryl or cycloalkyl; R 1 is as defined for R 1j , provided that R 1 is not unsubstituted aminoalkyl; L is CO; Y is a CH group; Cy is a saturated or unsaturated, mono or poly cyclic, homocyclic group optionally substituted by groups R 3a or phenyl optionally substituted by R 3a ; each R 3a independently is R 1c , amino, halo, cyano, nitro, thiol, alkylthio, alkylsulphonyl, alkylsulphenyl, triazolyl, imidazolyl, tetrazolyl, hydrazido, alkyl iymidazolyl, thiazolyl, alkyl thiazolyl, alkyl oxazolyl, oxazolyl, alkylsulphonamido, alkylaminosulphonyl, aminosulphonyl, haloalkoxy and haloalkyl; Lp(D) n is a lipophilic organic group selected from wherein R 3 is as defined for R 3a ; R 4 represents hydrogen, (CH 2 ) w COOH or (CH 2 ) w CONH 2 ; w represents an integer from 0 to 4; and when X is in the ring bonded to L, X is N and, otherwise X represents CH or N; and R 1c is as defined for R 1j , or a physioloqically tolerable salt thereof.