Patent ID: 7915252

Claim:
A compound represented by structural formula I or a pharmaceutically acceptable salt thereof; wherein: Q represents NR 2 R 3 or a group selected from the following: wherein said group may be optionally substituted with from one to five substituents selected from the group consisting of halo, C 1-3 alkyl, C 1-3 alkoxy, C 1-3 haloalkyl and hydroxyl; L represents the linking group —(CH 2 ) a —X—(CH 2 ) b —, wherein: X represents a bond or is selected from the group consisting of: O, S, NH, N(C 1-3 alkyl), C(O)NH, NHC(O), vinyl, Aryl, Aryloxy and HAR, when L is other than a bond, said group L is optionally substituted with 1-5 groups selected from: halo, cyano, C 1-4 alkoxy, C 1-4 alkylthio, hydroxy and amino; said Aryl, Aryloxy and HAR groups being optionally substituted with 1-5 groups selected from halo, cyano, C 1-4 alkoxy, C 1-4 alkylthio, hydroxy and amino; when X is O, S, NH or N(C 1-3 alkyl), a represents an integer of from 2-6 and b represents an integer of from 0-4, such that the sum of a and b is from 2-6; and when X is a bond, C(O)NH, NHC(O), vinyl, Aryl, Aryloxy or HAR, a and b each represent integers of from 0-6, such that the sum of a and b is 0 to 6; R 1 selected from the group consisting of: C 1-6 alkyl, C 2-6 alkenyl, Aryl or HAR, optionally substituted with one to five of the following groups: halo, cyano, C 1-4 alkoxy, C 1-4 alkylthio, hydroxy, amino, Aryl and HAR, said Aryl and HAR being further optionally substituted with one to three substituents independently selected from cyano, halo, hydroxy, amino, carboxy, trifluoromethyl, trifluoromethoxy, C 1-4 alkyl, and C 1-4 alkoxy; R 2 is H or C 1-3 alkyl; and R3 is a bicyclic or tricyclic alkyl moiety having 6-12 carbon atoms, optionally substituted with 1-4 substituents selected from the group consisting of C 1-4 alkyl, halo, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, OH, C 1-6 alkyl-SO 2 — and phenyl-SO 2 —, the alkyl and phenyl portions of C 1-6 alkyl-SO 2 — and phenyl-SO 2 — being optionally substituted with 1-3 halo, C 1-3 alkyl, haloC 1-3 alkyl, C 1-3 alkoxy and haloC 1-3 alkoxy groups.