Patent ID: 7022850

Claim:
A compound of formula I or II: wherein: X is O, or S Y 1 is H, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl or substituted cycloalkyl; Z is O or S; R 1 is H, or alkyl, R 2 and R 3 are, independently, H alkyl, cycloalkyl or halogen or R 2 and R 3 may be taken together to form a C 3 to C 7 cycloalkyl; n is 1 or 2; A is N; R 4 is H, C(═O)R 9 , C(═O)OR 10 , C(═O)NR 11 R 12 , or S(O) 2 R 13 , R 9 , R 10 , R 11 , R 12 , R 13 are independently H, alkyl optionally substituted with alkoxy, alkyl, halo, alkylthio, hydroxyl, cyano, carboxy, amino, amido, carbamoyl, urea or thiol; cycloalkyl, optionally substituted with halogen, alkyl, alkoxy, hydroxyl, amino, amido, carbamoyl, urea, nitro, cyano, thiol; o, aryl, optionally substituted with alkyl, alkcoxy, halo, cyano, hydroxyl, carboxy, carbamoyl, alkyoxycarbonyl, nitro, alkenyloxy, trifluoromethyl, amino, cycloalkyl, aryl, heteroaryl, cyano, alkyl, sulfoxyl, sulfonyl, or thiol; or heteroaryl, optionally substituted with halo, alkyl, alkenyl, alkynyl, aryl, nitro, cyano, hydroxyl, alkoxy, thioalkyl, carboxy, carbonyl, phenyl, benzyl, phenylethyl, phenoxy, phenylthio, cycloalkyl, heterocycloalkyl, heteroaryl, amion, amido, heteroaryl, amino or amido; and R 5 is H, or alkyl, optionally substituted with alkoxy, alkyl, halo, alkylthio, hydroxyl, cyano, carboxy, amino, amido, carbamoyl, urea or thiol.