Patent ID: 7094578

Claim:
A method for producing an alpha-1,2-fucosylated oligosaccharide blood type antigen, the method comprising contacting a Helicobacter alpha-1,2-fucosyltransferase polypeptide or bioactive fragment thereof with a type 1 or type 2 oligosaccharide substrate for sufficient time and under conditions such that an alpha-1,2-fucosylated oligosaccharide blood type antigen is produced, wherein the alpha-1,2-fucosyltransferase polypeptide is encoded by a polynucleotide identical to a polynucleotide that is amplified using Helicobacter genomic DNA as a template by PCR using a first primer comprising 5′-GAACACTCACACGCGTCTT-3′ (SEQ ID NO:3) and a second primer comprising 5′-TAGAATTAGACGCTCGCTAT-3′ (SEQ ID NO:4), wherein the bioactive fragment has alpha-1,2-fucosyltransferase activity.