Patent ID: 7973159

Claim:
A compound having the following Formula I, or a pharmaceutically acceptable salt thereof: wherein, A is CR 2 ; R 1 , R 1b and R 1a are the same or different and are each independently selected from the group consisting of H, halo, lower alkyl, cycloalkyl, CF 3 , alkoxy, and thioalkoxy; R 2 is H or lower alkyl; R 3 is H, halo, lower alkyl, cycloalkyl, CF 3 , lower alkoxy, thioalkoxy, or CN; R 4 is —OH or -G-D-Z n ; R 5 and R 5b are the same or different and are each independently selected from the group consisting of H, halo, and lower alkyl; n is 1 to 3; G is O or S; D is selected from the group consisting of lower alkyl, cycloalkylalkyl, cycloalkyl and wherein X is —O—, —S—, —SO— or —SO 2 —; Z is independently hydrogen, hydroxyl, polyhaloalkyl, lower alkyl, lower alkoxy, cycloalkyl, cycloalkoxy, OCONR 6 R 7 , CN, CONR 8 R 9 , SOR 10 , SO 2 R 11 , NR 12 COR 13 , NR 14 CO 2 R 15 , COR 16 , a 5- to 6-membered heteroaryl, or a 4- to 6-membered heterocycloalkyl containing no more that two heteroatoms wherein the heteroatoms are independently —O—, —S—, —SO— or —SO 2 —; R 6 , R 7 , R 8 , R 9 , R 12 and R 14 are the same or different and are each independently selected from the group consisting of H, lower alkyl and cycloalkyl or R 6 and R 7 and/or R 8 and R 9 together with the atoms to which they are attached may form a 4- to 7-membered ring; and R 10 , R 11 R 13 , R 15 and R 16 are the same or different and are each independently selected from the group consisting of lower alkyl, and cycloalkyl.