Patent ID: 7897387

Claim:
A method of screening for a compound that inhibits the amount of transport of a glycosylphosphatidylinositol (GPI)-anchored protein to the fungal cell wall, wherein the method comprises the steps of: (a) contacting a test compound with a protein having an activity of transporting the glycosylphosphatidylinositol (GPI)-anchored protein to the cell wall of the fungus wherein said protein is selected from the group consisting of: (i) a protein comprising the amino acid sequence of SEQ ID NO: 40, and (ii) a protein encoded by a DNA comprising the nucleotide sequence of SEQ ID NOs: 39, (b) detecting the binding activity between the protein and the test compound; and; (c) selecting the test compound as the compound that inhibits the amount of transport of a glycosylphosphatidylinositol (GPI)-anchored protein to the fungal cell wall as compared to the amount of transport of the GPI-anchored protein to the fungal cell wall in the absence of the test compound.