Patent ID: 8709818

Claim:
A method for analyzing the size distribution of lipoproteins, said method not including centrifugation, said method comprising: a) admixing a solution comprising lipoproteins and non-lipoproteins with one or more polyanionic compounds and one or more divalent cations; b) allowing a precipitate containing lipoproteins to form in said admixed solution; c) after step b), collecting the precipitated lipoproteins; and d) subjecting said one or more lipoproteins to differential charged particle mobility analysis, said analysis comprising: (i) determining a particle size distribution in one or more regions of particle sizes; (ii) subtracting contribution to the particle size distribution of a non-lipoprotein reagent or a non-lipoprotein sample material to obtain a lipoprotein particle size distribution; and (iii) outputting the lipoprotein particle size distribution to a display, a printer or a memory thereby determining the size distribution of said lipoproteins, wherein the determining a particle size distribution includes determining a best fit for the one or more regions.