Patent ID: 6903218

Claim:
A compound formula wherein R is hydrogen, hydroxy, oxo, halo, C 1 -C 10 haloalkyl, C 1 -C 10 alkyl, cyano, nitro, NR 1 R 1 , SR 1 , OR 1 , SO 2 R 2 , OCOR 2 , NR 1 COR 2 , COR 2 , NR 1 SO 2 R 2 , NR 1 CO 2 R 1 , pyrrole, or Ar 2 , optionally substituted with hydroxy, halogen, cyano, NR 1 R 1 , SR 1 , trifluoromethyl, OR 1 , C 3 -C 8 cycloaklyl, phenyl, NR 1 COR 2 , COR 2 , SO 2 R 2 , OCOR 2 , NR 1 SO 2 R 2 , or NR 1 CO 2 R 1 ; R 1 is hydrogen, C 1 -C 10 alkyl optionally substituted with 1 to 4 substituents selected from hydroxy, halogen, CO 2 H, CO 2 C 1 -C 10 alkyl, SO 2 C 1 -C 10 alkyl, C 1 -C 10 alkoxy; or C 3 -C 8 cycloalkyl, phenyl or naphthyl, each optionally substituted with 1 to 4 substituents selected from halogen, nitro, oxo, C 1 -C 10 alkyl, C 1 -C 10 alkoxy, and C 1 -C 10 alkylthio; R 2 is R 1 or NR 1 R 1 ; R 3 is hydrogen, C 1 -C 10 alkyl or Ar 1 is Ar 1 —O—CH 2 , phenyl, or a 5 or 6 membered heterocyclic ring with from 1 to 4 heteroatoms selected from O, S and N, each moiety being optionally fused to a 5 membered heterocyclic ring containing from 1 to 4 hetero atoms selected from O, S, and N, the fused heterocyclic ring being optionally fused to a phenyl ring or substituted with oxo; m is 1; X is SO 2 -piperizmyl, NR 3 —SO 2 , or SO 2 —NR 3 ; n is 0, 1, 2, 3, or 4; Ar 2 is phenyl, or a 5 or 6 membered heterocyclic ring with from 1 to 4 heteroatoms selected from O, S and N, each moiety being optionally substituted with halogen, C 1 -C 10 alkyl, C 1 -C 10 alkoxy, and OR, or being fused to a 5 membered heterocyclic ring containing from 1 to 4 hetero atoms selected from O, S, and N, the fused heterocyclic ring being optionally fused to a phenyl ring or optionally substituted with oxo; Y is O—Y, NR 1 , NR 1 CO, C 3 -C 8 cycloalkyl or a 5 or 6 membered heterocyclic ring with from 1 to 4 heteroatoms selected from O, S and N, each of which is optionally substituted with oxo; p is 0 or 1; R 4 is hydrogen, R 1 , R 2 , oxo, C 1 -C 10 heteroalkyl, C 1 -C 10 alkyl, C 1 -C 10 haloalkyl, each being optionally substituted with C 3 -C 8 cycloalkyl, phenyl, naphthyl, benzofuran, carbazole, dibenzothiofuran, or a 5 or 6 membered heterocyclic ring with from 1 to 4 heteroatoms selected from O, S, and N, each ring structure being optionally substituted with halo and C 1 -C 10 alkyl.