Patent ID: 8114874

Claim:
A compound of formula: wherein: L 1 is NR 1 C(O) or C(O)NR 1 ; Ring D represents a 5- or 6-membered heterocyclic or heteroaryl ring comprising carbon atoms and 1-3 heteroatoms independently selected from O, N and S(O) r ; Ring C is a 5- or 6-membered heterocyclic or heteroaryl ring, comprising carbon atoms and 1-3 heteroatoms independently selected from O, N and S(O) r ; L 2 is —(CH 2 ) z —; each occurrence of R a is independently selected from the group consisting of halo, alkyl and cycloalkyl; each occurrence of R b is independently selected from the group consisting of halo, alkyl and cycloalkyl; each occurrence of R c is independently selected from the group consisting of halo, alkyl and cycloalkyl; each occurrence of R d is independently selected from the group consisting of halo, alkyl and cycloalkyl and —NR 2 R 3 ; each occurrence of R e is independently selected from the group consisting of halo, alkyl, cycloalkyl, —NR 2 R 3 , alkoxy, amino, —NH-alkyl, —C(O)NH-alkyl, —NHC(O)-alkyl, —NHC(O)NH-alkyl, —NHC(NH)-alkyl, —NHC(NH)NH 2 , —NH(CH 2 ) x -heteroaryl, —NH(CH 2 ) x -heterocyclyl, —NH(CH 2 ) x -aryl, and —(CH 2 ) x C(O)NH 2 , wherein x is 0, 1, 2 or 3; each of R 1 , R 2 and R 3 is independently selected from H, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl, heterocyclyl, and heteroaryl, or R 2 and R 3 , taken together with the nitrogen atom to which at least one of R 2 and R 3 is attached, form a 5- or 6-membered heterocyclyl or heteroaryl ring; each of the alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, and heterocyclyl moieties is unsubstituted or substituted with one or more groups selected from amino, alkylamino, dialkylamino, aminocarbonyl, halogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbocyclyl, heterocyclyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkylaminocarbonyloxy, dialkylaminocarbonyloxy, nitro, cyano, carboxy, alkoxycarbonyl, alkylcarbonyl, hydroxy, alkoxy, acyloxy, haloalkoxy, ═O, ═S, ═NH, ═NNR 2 R 3 , ═NNHC(O)R 2 , ═NNHCO 2 R 2 , and ═NNHSO 2 R 2 , and each of the aryl and heteroaryl moieties is unsubstituted or substituted with one or more groups selected from amino, alkylamino, dialkylamino, aminocarbonyl, halogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbocyclyl, heterocyclyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkylaminocarbonyloxy, dialkylaminocarbonyloxy, nitro, cyano, carboxy, alkoxycarbonyl, alkylcarbonyl, hydroxy, alkoxy, acyloxy, and haloalkoxy; m is 0, 1, 2, 3, or 4; p is 0, 1, 2, 3, or 4; r is 0, 1, or 2; s is 0, 1, 2, or 3; v is 0, 1, 2, 3, 4, or 5; w is 0, 1, 2, 3, 4, or 5; and z is 1, 2, 3 or 4; or a pharmaceutically acceptable salt thereof.