Patent ID: 8008258

Claim:
A method for inhibiting weight loss, inducing weight regain or reducing macroscopic colonic damage in a patient suffering from severe Crohn's disease, comprising administering to said patient by daily injection an amount of an active agent selected from the group consisting of i) Copolymer 1 and Copolymer 1-related peptides consisting of random three- or four-amino acid copolymers made up of one amino acid selected from three or four of the following groups: (a) lysine and arginine; (b) glutamic acid and aspartic acid; (c) alanine and glycine; and (d) tyrosine and tryptophan; and ii) a Copolymer 1-related peptide having the sequence of any of SEQ ID NOs: 1-32, in an amount effective for inhibiting weight loss, inducing weight regain or reducing macroscopic colonic damage in the patient.