Patent ID: 7704964

Claim:
A chimeric genetic construct, wherein said construct encodes a polypeptide of interest fused to a targeting polypeptide, said polypeptide of interest being selected from an antigen, a cytokine, a ligand, a receptor, an immunoglobulin, a marker polypeptide, an enzyme and an ionic channel, or a portion thereof, and said targeting polypeptide being a partial human lactadherin sequence selected from the group consisting of the C1 domain of the human lactadherin sequence consisting essentially of amino acid residues 69-225 of SEQ ID NO:7, the C2 domain of the human lactadherin sequence consisting essentially of amino acid residues 229-387 of SEQ ID NO:7, and the C1 and C2 domain of the human lactadherin consisting essentially of amino acid residues 69-387 of SEQ ID NO:7, wherein said targeting polypeptide selectively targets said polypeptide of interest to exosomes.