Patent ID: 7605153

Claim:
A method of treating mucoviscidosis in a subject, the method comprising administering to the subject in need thereof a therapeutically effective amount of a paullone derivative represented by the formula (I): Wherein —X represents a C=0, C—S—CH 3 , C—S or —C—NHOH group; Z represents C or N; Y represents a phenyl or a thienyl residue, together with the adjacent ring; the ring(s) that constitute such derivatives being substituted as the case may be with one or more halogen atoms, hydroxyl, alkylenehydroxyl, alkynalkylenehydroxyl, alkynhydroxycyclohexyl, alkyl, alkoxyl, alkylenealkoxyl, alkylenecyano groups, the alkylene group being saturated or unsaturated, such C1 to C18 radicals having a straight or branched chain, said chain may be substituted with one or more hydroxyl or amino groups, one or more trifluoromethyl groups, —COM, —COOM, or —CH 2 COOM group (where M represents a hydrogen atom or a C1 to C18 alkyl group with a straight or branched chain substituted as the case may be with one or more hydroxyl and/or amino groups), a nitroso or a cyano group; R 5 represents a hydrogen atom or a C1 to C5 alkyl group R 12 represents a hydrogen atom or a —C—CO 2 —(CH 3 ) 3 group, and the physiologically acceptable salts of these derivatives.