Patent ID: 7550428

Claim:
A method for treating a fungal infection in a mammal in need thereof, which comprises administering to said mammal the echinocandin/carbohydrate complex comprising a carbohydrate and an echinocandin compound represented by the following structure: wherein: R is an alkyl group, an alkenyl group, an alkynyl group, an aryl group, heteroaryl group, or combinations thereof; R 1 , R 2 , R 3 , R 6 , R 7 , and R 10 are independently hydroxy or hydrogen; R 4 is hydrogen, methyl or —CH 2 C(O)NH 2 ; R 5 and R 11 are independently methyl or hydrogen; R 8 is —OH, —OSO 3 H, —OPO 3 H 2 , —OPO 3 HR a , or —OPO 2 HR a , where R a is hydroxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, phenyl, phenoxy, p-halophenyl, p-halophenoxy, p-nitrophenyl, p-nitrophenoxy, benzyl, benzyloxy, p-halobenzyl, p-halobenzyloxy, p-nitrobenzyl, or p-nitrobenzyloxy; R 9 is —H, —OH, or —OSO 3 H; and pharmaceutically acceptable salts or hydrates thereof; wherein the carbohydrate is released upon dispersion of the echinocandin/carbohydrate complex in water.