Patent ID: 8268965

Claim:
An in vitro assembly for use in protein assays, said assembly comprising: a plurality of a first membrane-associated receptor protein domain component; and a lipid bilayer membrane comprising a first phospholipid component modified for binding with said first membrane-associated receptor protein domain component, said first membrane-associated receptor protein domain component having a binding affinity for said modified binding component and being coupled with said lipid bilayer membrane by interaction with said modified binding component to promote a two dimensional cooperatively interactive organization of said plurality of first membrane-associated receptor protein domain component that mimics a natural organization of said first membrane-associated modified phospholipid receptor protein component on a cell membrane; wherein said first-membrane-associated receptor protein domain component, when coupled with said lipid bilayer membrane, exhibits biological function that more closely mimics its function than the first membrane-associated receptor protein domain component in solution in the absence of the lipid bilayer membrane.