Patent ID: 8128944

Claim:
A composition comprising a single-stranded nucleotide polymer comprising an immunostimulatory RNA motif -C-U-C-A-, wherein said polymer is selected from A-A-A-C-G-C-U-C-A-G-C-C-A-A-A-G-C-A-G (SEQ ID NO 3); A-A-A-C-G-C-U-C-A-C-C-C-A-A-A-G-C-A-G (SEQ ID NO 17); A-A-A-C-A-C-U-C-A-G-C-C-A-A-A-G-C-A-G (SEQ ID NO 22); and A-A-A-C-C-C-U-C-A-G-C-C-A-A-A-G-C-A-G (SEQ ID NO 23); and a delivery vehicle, wherein the delivery vehicle is a liposome, a noisome, a lipoplexe, a polyplexe, a lipopolyplexe, a water-in-oil emulsion, an oil-in-water emulsion, a water-in-oil-in water multiple emulsion, a micro-emulsion, a nano-emulsion, a micelle, a dendrimer, a virosome, a virus-like particle, a polymeric nanoparticle, or a polymeric microparticle and wherein the composition does not include lipofectin, and wherein “-” depicts a phosphodiester backbone.