Patent ID: 8729066

Claim:
A compound having Formula I, its enantiomers, diastereoisomers, tautomers or a pharmaceutically acceptable salt thereof, wherein: R 1 is H or substituted or unsubstituted C 1-6 alkyl; R 2 is H or substituted or unsubstituted C 1-6 alkyl; R 3 is C-R 7 ; R 4 is C-R 8 ; R 5 is selected from 5-isoxazol-3-ylthiophene, 2-oxo-2,3-dihydro-1,3-benzoxazole, 1,3-benzothiazole, 1,3-benzodioxole, 4-methyl-1,3-thiazol-2-yl-acetamide, 1-(phenylsulfonyl)-1H-pyrrole, 2-oxo-2H-chromene, imidazo[2,1-b][1,3]thiazole, 6-morpholin-4-ylpyridine, 2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine, 5-isoxazol-5-ylthiophene, 6-chloroimidazo[2,1-b][1,3]thiazole, 4-methyl-3,4-dihydro-2H-1,4-benzoxazine, 3,4-dihydro-2H-1,5-benzodioxepine, 2,2-dimethylchromane, 5-pyridin-2-yl-2-thienyl, 4-methyl-3,4-dihydro-2H-pyrido[3,2b][1,4]oxazine, 3-oxo-3,4-dihydro-2H-1,4-benzoxazine, 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline and 4-acetyl-3,4-dihydro-2H-1,4-benzoxazine; R 6 is 2-benzofuran; R 15 is C-R 16 ; R 17 is C-R 18 ; R 7 is H, substituted or unsubstituted C 1-6 alkyl or halogen; R 8 is H, substituted or unsubstituted C 1-6 alkyl or halogen; R 16 is H, substituted or unsubstituted C 1-6 alkyl or halogen; and R 18 is H, substituted or unsubstituted C 1-6 alkyl or halogen.