Patent ID: 8168651

Claim:
A compound of Formula IA: wherein: Z 60 and Z 70 are independently N or CR 60 , provided at least one of them is N; R 30 and each R 60 is independently H or an optionally substituted C1-C8 alkyl or C2-C8 heteroalkyl, each R 40 is H or optionally substituted member selected from the group consisting of C 1 -C 6 alkyl, C2-C6 heteroalkyl, and C1-C6 acyl; each R 50 is independently an optionally substituted member selected from the group consisting of C 1-10 alkyl, C 2-10 alkenyl, C 2-10 heteroalkyl, C 3-8 carbocyclic ring, and C 3-8 heterocyclic ring optionally fused to an additional optionally substituted carbocyclic or heterocyclic ring; or R 50 can be a C 1-10 alkyl, C 2-10 alkenyl, or C 2-10 heteroalkyl substituted with an optionally substituted C 3-8 carbocyclic ring or C 3-8 heterocyclic ring; in each —NR 40 R 50 , R 40 and R 50 together with N may form an optionally substituted 3-8 membered ring, which may optionally contain an additional heteroatom selected from N, O and S as a ring member; and each R 3P represents a polar substituent selected from the group consisting of tetrazole, triazole, imidazole, oxadiazole, oxothiadiazole, thiazole, aminothiazole, and hydroxythiazole; or a pharmaceutically acceptable salt thereof.