Patent ID: 8632770

Claim:
A Factor IX peptide conjugate comprising a glycosyl linking group attached to an amino acid residue of a Factor IX peptide comprising SEQ ID NO: 1, wherein the glycosyl linking group is attached to an amino acid of SEQ ID NO: 1 selected from the group consisting of Asn 157 and Asn 167, the glycosyl linking group comprising a modified sialyl residue having the formula: wherein R 2 is H, CH 2 OR 7 , COOR 7 or OR 7 wherein R 7 represents H, substituted or unsubstituted alkyl or substituted or unsubstituted heteroalkyl; R 3 and R 4 are members independently selected from H, substituted or unsubstituted alkyl, OR 8 , NHC(O)R 9 wherein R 8 and R 9 are independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl or sialic acid; L a is a linker selected from a bond, substituted or unsubstituted alkyl and substituted or unsubstituted heteroalkyl′ R 16 and R 17 are independently selected polymeric arms; X 2 and X 4 are independently selected linkage fragments joining polymeric moieties R 16 and R 17 to C; and X 5 is a non-reactive group.