Patent ID: 8722675

Claim:
A method for the treatment of neuropathic pain in a subject comprising administering to the subject an effective amount of an AT 2 receptor antagonist, wherein the AT 2 receptor antagonist is selected from compounds represented by the formula (IV): wherein: R 10 is selected from H, halogen, C 1-6 alkyl, phenyl, substituted phenyl, substituted C 1-6 alkyl, or C 1-6 alkoxy, R 9 is selected from —NR 13 R 14 , wherein R 13 and R 14 are independently selected from C 1-6 alkyl, substituted C 1-6 alkyl, aryl, substituted aryl, benzyl, substituted benzyl, C 1-4 alkylaryl, substituted C 1-4 alkylaryl, OH, or NH 2 ; a five or six membered, unsaturated, substituted or unsubstituted, heterocyclic ring selected from: V is selected from CH or a nitrogen atom, Y is selected from sulfur, oxygen or N—R N , where R N is selected from H, C 1-6 alkyl, substituted C 1-6 alkyl, aryl, substituted aryl, benzyl, substituted benzyl, C 1-4 alkylaryl, substituted C 1-4 alkylaryl, OH, or NH 2 , G is a five or six membered homoaromatic or heterocyclic, unsaturated, substituted ring selected from the following rings systems: where the symbol ‘*’ indicates the bond shared between the fused rings ‘A’ and ‘G’, R 5 is selected from C 1-6 alkyl, phenyl, substituted phenyl, substituted C 1-6 alkyl, or C 1-6 alkoxy, R 6 and R 8 are independently selected from H, C 1-6 alkyl, substituted C 1-6 alkyl, C 1-6 alkoxy, substituted C 1-6 alkoxy, phenyl, phenyloxy, benzyl, benzyloxy, benzylamino, biphenyl, substituted biphenyl, biphenyloxy, substituted biphenyloxy, naphthyl, substituted naphthyl, provided that one of R 6 or R 8 is not hydrogen, and R 7 is selected from phenyl, substituted phenyl, benzyl, substituted benzyl, biphenyl, substituted biphenyl, biphenylmethylene, substituted biphenylmethylene, naphthyl, substituted naphthyl, naphthylmethylene, and substituted naphthylmethylene, and pharmaceutically compatible salts thereof.