Patent ID: 7109184

Claim:
A compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof, wherein: R1 and R2 are independently —H, an electron withdrawing group or a C1–C10 alkyl group; Y is a substituted methylene group and R3 is a hydrocarbyl group optionally comprising one or more amine, ammonium, ether, thioether or phenylene linking groups; a substituted hydrocarbyl group optionally comprising one or more amine, ammonium, ether, thioether or phenylene linking groups; a heteroaryl group; a substituted heteroaryl group; or a phenyl group substituted with one or more groups selected from —Cl, —Br, —F, —CN, —NO 2 , —OR a , —N(R a ) 2 , —COOR, —CON(R a ) 2 , —COR a , —S(O)R a , —S(O) 2 R a , —S(O) 2 N(R a ) 2 , —NR a S(O) 2 R a , —NR a COR a , a halogenated lower alkyl group, an aryl group, a substituted aryl group, or a halogenated alkoxy group; or Y is an unsubstituted methylene group and R3 is a C7–C18 saturated unsubstituted hydrocarbyl group, or a C7–C18 saturated monosubstituted hydrocarbyl group wherein the substituent is at the terminal position; and each Rb is independently —H, a lower alkyl group or a phosphate protecting group; and each R a is independently —H, lower alkyl, substituted lower alkyl, aryl or substituted aryl.