Patent ID: 8309767

Claim:
A compound having the formula (I): or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is C 1-6 alkylene; R is hydrogen, haloalkyl, aryl, a heterocyclic group, a heteroaryl group, alkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, hydroxyalkyl, nitro, amino, cyano, cyanamido, guanidine, amidino, acylamido, hydroxy, thiol, acyloxy, azido, alkoxy, carboxy, carbonylamido, S-alkyl or alkylthiol, R 1 and R 2 are independently hydrogen, halo, haloalkyl, aryl, a heterocyclic group, a heteroaryl group, alkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, hydroxyalkyl, nitro, amino, cyano, cyanamido, guanidine, amidino, acylamido, hydroxy, thiol, acyloxy, azido, alkoxy, carboxy, carbonylamido, S-alkyl or alkylthiol, X is >C 1-6 alkylene, >C═O or >C═S or a single bond; and Y is halo, a heterocyclic group, alkenyl, alkynyl, arylalkenyl, arylalkynyl, hydroxyalkyl, nitro, amino, cyano, cyanamido, guanidine, amidino, acylamido, hydroxy, thiol, azido, carboxy, carbonylamido, or styryl, wherein where Y is a ring it may be ring-substituted by up to four substituents independently selected from among hydrogen, halo, haloalkyl, aryl, a heterocyclic group, a heteroaryl group, alkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, hydroxyalkyl, nitro, amino, cyano, cyanamido, guanidine, amidino, acylamido, hydroxy, thiol, acyloxy, azido, alkoxy, S-alkyl, alkylthiol, or —COQ, where Q is hydroxy, C 1-6 alkoxy, amino, mono- C 1-6 alkylamino, di- C 1-6 alkylamino, hydroxylamino, C 1-4 alkoxyamino or aryl-C 1-4 -alkoxyamino.