Patent ID: 8324355

Claim:
An antibody comprising an antigen recognition region capable of specifically binding a compound having the general Formula (I): wherein: m and n are each independently an integer from 1 to 6; X 1 -X 3 and Y 1 -Y 3 are each O; R 1 -R 3 are each independently selected from the group consisting of hydrogen or alkyl; and R is O—(CH 2 )x-C(═O)NR′—(CH 2 )y-NHR′ whereas: x and y are each independently an integer from 1 to 6; and R′ is selected from the group consisting of hydrogen and alkyl; the antibody being capable of inhibiting the activity of matrix metalloproteinase-9 (MMP-9) and matrix metalloproteinase-2(MMP-2) with a Ki of less than 5 μM.