Patent ID: 7211596

Claim:
An injectable pharmaceutical composition comprising water and 3 to 60 mg/mL, per total volume of the injectable pharmaceutical composition, of a pyrazolone derivative of the following formula (I): wherein R 1 represents hydrogen atom, an aryl, an alkyl having 1 to 5 carbon atoms or an alkoxycarbonylalkyl having 3 to 6 carbon atoms in total, R 2 represents hydrogen atom, an aryloxy, an arylmercapto, an alkyl having 1 to 5 carbon atoms or a hydroxyalkyl having 1 to 3 carbon atoms, or R 1 and R 2 is coupled together to form an alkylene having 3 to 5 carbon atoms, and R 3 represents hydrogen atom, an alkyl having 1 to 5 carbon atoms, a cycloalkyl having 5 to 7 carbon atoms, a hydroxyalkyl having 1 to 3 carbon atoms, benzyl, naphthyl, phenyl, or a phenyl substituted with 1 to 3 substituents, which may be the same or different and are selected from the group consisting of an alkoxy having 1 to 5 carbon atoms, a hydroxyalkyl having 1 to 3 carbon atoms, an alkoxycarbonyl having 2 to 5 carbon atoms in total, an alkylmercapto having 1 to 3 carbon atoms, an alkylamino having 1 to 4 carbon atoms, a dialkylamino having 2 to 8 carbon atoms in total, a halogen atom, trifluoromethyl, carboxyl, cyano, hydroxyl group, nitro, amino, and) acctamido, or physiologically acceptable salt thereof, or a hydrate or solvate thereof.