Patent ID: 8137693

Claim:
A targeted drug delivery nanocarrier, the nanocarrier comprising: a plurality of phospholipid molecules; a targeting landscape phage protein assembly that is denatured and has a spheroid conformation; and a plurality of drug molecules; wherein the phospholipid molecules form a liposome comprising a phospholipid bilayer having the drug molecules contained therein and the targeting landscape phage protein assembly is complexed to the liposome via self-assembly and proteins of the targeting landscape phage protein assembly are oriented with their N-terminus on the surface of the liposome and their C-terminus in the interior of the liposome and wherein the targeting landscape phage protein assembly displays a binding peptide on the surface of the liposome that is selected to specifically and selectively bind to a target site, and wherein the landscape phage protein assembly is a filamentous bacteriophage coat protein assembly that displays the binding peptide in a pVIII major coat protein.