Patent ID: 8653132

Claim:
A pharmaceutical composition, comprising; at least one isolated monomeric pyrophosphate-platinum complex comprising a platinum center selected from Pt(II) and Pt(IV) and having a formula selected from I, II, III, and IV: wherein each R 1 and R 2 is independently selected from NH 3 , methyl amine, ethyl amine, propyl amine, isopropyl amine, butyl amine, cyclohexane amine, aniline, pyridine, and substituted pyridine; wherein R 1 and R 2 are not both NH 3 for formula (I); wherein each R 3 is selected from substituted or unsubstituted aliphatic or aromatic diamines; and wherein each S is independently selected from hydroxide, acetic acid, butyric acid, and alpha-hydroxy acids; or pharmaceutically acceptable salts thereof; wherein the composition does not comprise diammine(dihydrogen pyrophosphato)platinum(II) or 1,2-Ethanediamine(dihydrogen pyrophosphato)platinum (II).