Patent ID: 7300929

Claim:
A method for treating a basal cell carcinoma or lung cancer in a patient, comprising administering to the patient a compound of formula (I): wherein, as valence and stability permit, R 1 , R 2 , R 3 , and R 4 , independently for each occurrence, represent H, lower alkyl, —(CH 2 ) n aryl, or —(CH 2 ) n heteroaryl; L, independently for each occurrence, is absent or represents —(CH 2 ) n —, -alkenyl-, -alkynyl-, —(CH 2 ) n alkenyl-, —(CH 2 ) n alkynyl-, —(CH 2 ) n O(CH 2 ) p —, —(CH 2 ) n NR 8 (CH 2 ) p —, —(CH 2 ) n S(CH 2 ) p —, —(CH 2 ) n alkenyl(CH 2 ) p —, —(CH 2 ) n alkynyl(CH 2 ) p —, —O(CH 2 ) n —, —NR 8 (CH 2 ) n —, or —S(CH 2 ) n —; X and D, independently, are selected from —N(R 8 )—, —O—, —S—, —(R 8 )N—N(R 8 )—, —ON(R 8 )—, and a direct bond; Y and Z, independently, are selected from O and S; E represents O, S, or NR 5 , wherein R 5 represents LR 8 or —(C═O)LR 8 , R 8 , independently for each occurrence, represents H, lower alkyl, —(CH 2 ) n aryl, or —(CH 2 ) n heteroaryl, or two R 8 taken together form a 4- to 8-membered ring; p represents, independently for each occurrence, an integer from 0 to 3; n, individually for each occurrence, represents an integer from 0 to 5; and q and r represent, independently for each occurrence, an integer from 0 to 2, or a pharmaceutically acceptable salt thereof.