Patent ID: 6969715

Claim:
A compound having the structure: wherein Z 1 is selected from the group consisting of an optionally substituted C 2 to C 8 alkyl, optionally substituted C 3 to C 6 cycloalkyl and optionally substituted phenyl; Z 3 comprises a 5- or 6-membered heterocyclic or aromatic ring substituted with an amidine or a derivatized amidine group which, upon hydrolysis, oxidation, reduction or elimination yields an amidine group, the ring atoms of the 5- or 6-membered heterocyclic or aromatic ring of Z 3 being carbon, sulfur, nitrogen, or oxygen; Z 4 comprises a 5- or 6-membered heterocyclic or carbocyclic ring, the ring atoms of Z 4 being Z 40 , Z 41 , Z 42 , Z 44 and Z 45 , when Z 4 is a 5-membered ring and Z 40 , Z 41 , Z 42 , Z 43 , Z 44 and Z 45 when Z 4 is a 6-membered ring, Z 40 , Z 41 , Z 42 , Z 43 , Z 44 and Z 45 , being carbon, nitrogen, oxygen or sulfur, Z 40 being the ring atom through which Z 4 is attached to the heterocyclic core ring, Z 41 and Z 45 each being in an alpha position relative to Z 40 , Z 42 and Z 44 each being in a beta position relative to Z 40 , Z 43 being in the gamma position relative to Z 40 when Z 4 is a 6-membered ring, Z 4 having a substituent R 42 covalently attached to Z 42 , and a second substituent bonded to one of Z 41 , Z 43 , Z 44 , or Z 45 , the substituent being R 41 when bonded to Z 41 , the substituent being R 43 when bonded to Z 43 , the substituent being R 44 when bonded to Z 44 , and the substituent being R 45 when bonded to Z 45 ; R 42 is amino; and R 41 , R 43 , R 44 and R 45 are independently hydrogen, hydrocarbyl, substituted hydrocarbyl, heterocyclo, halogen, or a substituted or unsubstituted heteroatom selected from nitrogen, oxygen, sulfur and phosphorus, provided at least one of R 41 , R 43 , R 44 or R 45 is other than hydrogen.