Patent ID: 8394794

Claim:
A compound of formula (I): wherein: R 1 is (C 1 -C 6 )alkoxy or NR a R b ; R 2 is cyano, (C 1 -C 6 )alkoxycarbonyl or —C(O)NR e R f ; R 3 is halo, cyano, (C 1 -C 6 )alkyl, cycloalkyl, aryl, heteroaryl, aryl(C 1 -C 6 )alkyl or (C 1 -C 6 )alkoxycarbonyl; each of R 6 , R 7 and R 8 is independently hydrogen, halo, cyano, (C 1 -C 6 )alkyl, cycloalkyl, aryl, heteroaryl, aryl(C 1 -C 6 )alkyl or (C 1 -C 6 )alkoxycarbonyl; R c and R d are independently hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkanoyl or arylcarbonyl; or R c and R d taken together with the nitrogen to which they are attached form a pyrrolidino, piperidino, piperazino, or morpholino ring; R e and R f are independently hydrogen or (C 1 -C 6 )alkyl; or R c and R d taken together with the nitrogen to which they are attached form a pyrrolidino, piperidino, piperazino, or morpholino ring; R 4 and R 5 are each hydrogen; or R 4 is (C 1 -C 6 )alkyl and R 5 is cyano; R a and R b are independently hydrogen or (C 1 -C 6 )alkyl; or R a and R b taken together with the nitrogen to which they are attached form a pyrrolidino, piperidino, piperazino, or morpholino ring; wherein any aryl or heteroaryl of R 3 , R 6 , R 7 or R 8 is optionally substituted with one or more groups independently selected from halo, hydroxy, cyano, CF 3 , OCF 3 , OCHF 2 , (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkanoyl, aryloxy, NR g R h , benzyloxy, (C 1 -C 6 )alkoxycarbonyl, and (C 1 -C 6 )alkanoyloxy; and each R g and R h is independently hydrogen or (C 1 -C 6 )alkyl; or R g and R h taken together with the nitrogen to which they are attached form a pyrrolidino, piperidino, piperazino, or morpholino ring; or a salt thereof.