Patent ID: 7026472

Claim:
An N-thiolated β-lactam compound having the structure of Formula A, in which R 1 is a hydrocarbon group having 1–8 carbon atoms; R 3 is an —S-alkyl or —S-aryl wherein the alkyl or aryl group has 1–12 carbon atoms; and R 4 is cycloalkyl, heterocycloalkyl, cycloalkenyl, or heterocycloalkenyl, any of which can be optionally substituted with R 2 , wherein R 2 is one or more halides, hydroxyl, nitro, cyano, alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, cycloalkenyl, heterocycloalkenyl, alkoxy, amido, amino, —CO 2 alkyl, wherein the alkyl group has 1–10 carbons, CHO, COOH, or COX, wherein X is Cl, F, Br, or I; or a pharmaceutically acceptable salt thereof.