Patent ID: 7785873

Claim:
A composition comprising: (a) a core particle with at least one first attachment site, wherein said core particle is a virus-like particle of RNA-phage Qβ; and (b) at least one antigen or antigenic determinant with at least one second attachment site, wherein said antigen or antigenic determinant is a Receptor Activator of NFkB Ligand (RANKL) protein, RANKL fragment or RANKL peptide, and wherein said second attachment site being selected from the group consisting of: (i) an attachment site not naturally occurring with said antigen or antigenic determinant; and (ii) an attachment site naturally occurring with said antigen or antigenic determinant, wherein said second attachment site associates with said first attachment site through at least one covalent non-peptide bond; and wherein said antigen or antigenic determinant and said core particle interact through said association to form an ordered and repetitive antigen array.