Patent ID: 8084036

Claim:
A compound that comprises: at least one human or bacterial sialidase or active portion thereof, wherein the sialidase or active portion has sialidase activity that cleaves α(2,3)-Gal and/or α(2,6)-Gal linkages; and at least one peptide or protein that binds to a glycosaminoglycan (GAG) on the surface of a target cell, wherein the peptide or protein that binds to a GAG comprises the GAG-binding amino acid sequence of: human platelet factor 4 (SEQ ID NO:2), human interleukin 8 (SEQ ID NO:3), human antithrombin III (SEQ ID NO:4), human apoprotein E (SEQ ID NO:5), human angio-associated migratory protein (SEQ ID NO:6), or human amphiregulin (SEQ ID NO:7).