Patent ID: 7364739

Claim:
An isolated lipopolysaccharide moiety consisting essentially of a triheptosyl inner-core moiety having the structure II: wherein R 1 is hydrogen, β-D-Glcp(1→4), or PCho→6)-β-D-Glcp(1→4); R 2 is phosphate (P) or pyrophosphoethanolamine (P-PEtn); R 3 is hydrogen, β-D-Glcp or β-D-Galp, and when R 1 is hydrogen or β-D-Glcp(1→4), then R 3 may also be β-D-Galp-(1→4)-β-D-Glcp, α-D-Galp-(1→4)-β-D-Galp-(1→4)-β-D-Glcp, β-D-GalpNAc-(1→3)-α-D-Galp-(1→4)-β-D-Galp-(1→4)-β-D-Glcp, or α-NeuAc(2→3)-β-D-Galp-(1→4)-β-D-Glcp-(1→3), wherein R 3 is attached at either the O-3 or O-2 position of HepIII; Kdo is 3-deoxy-D-manno-2-octulosonic acid; and Lipid A is detoxified.