Patent ID: 8883207

Claim:
A controlled release formulation comprising, two or more subunits wherein at least one of said subunits is an immediate release carvedilol subunit comprising a therapeutically effective amount of carvedilol free base or carvedilol salt thereof, a matrix forming polymer, and a pharmaceutically acceptable carrier, and wherein at least one of said subunits is a slow release carvedilol subunit comprising a therapeutically effective amount of carvedilol free base or carvedilol salt thereof, a matrix forming polymer, a solubility enhancer and a pharmaceutically acceptable carrier, wherein the matrix forming polymer comprises ethycellulose having an ethoxyl content of about 20% to about 80% (w/w), or the matrix forming polymer comprises hydroethylmethylcelluose (HEMC) having a methoxyl content of from about 10% to about 60% (w/w).