Patent ID: 8252790

Claim:
A compound of the following general formula (I) or its pharmaceutically acceptable salt, wherein, A is a 3 to 8 membered ring and may contain 0 to 4 heteroatoms selected from O, S, and N; R 1 is a C 1 -C 6 alkyl group, or a C 1 -C 6 haloalkyl group; R 2 is a saturated or partially or all unsaturated monocyclic or bicyclic aryl group, which may be substituted by R 4 ; R 3 is a hydrogen or halogen atom; R 4 is a C 1 -C 6 alkyl group, a C 1 -C 6 haloalkyl group, OH, OR 1A , halogen, —(CH 2 )aOH, CO 2 H, CONH 2 , CONHR 1A , CONR 1A R 1A , CN, COR 1A , NH 2 , NHR 1A , NR 1A R 1A , NHCOR 1A , SR 1A , SOR 1A , SO 2 R 1A , SO 2 NH 2 , SO 2 NHR 1A , SO 2 NR 1A R 1A , or NHSO 2 R 1A ; when R 4 has two R 1A , they may be same or different, or R 1A may combine with the other R 1A ; R 5 is a C 1 -C 6 alkyl group, —(CH 2 )aOH, —(CH 2 )aOR 1B , halogen, CONH 2 , CONR 1B R 1B , COR 1B , SO 2 R 1B , —OCH 2 CH 2 NR 1B R 1B or a C 1 -C 6 haloalkyl group; when p is plural; R 5 may be the same or different, or R 5 may combine with another R 5 ; R 1A and R 1B are each independently a C 1 -C 6 alkyl group or a C 1 -C 6 haloalkyl group; a is 0, 1, or 2; n is 1, or 2; and p is 0, 1, 2, 3, 4, or 5.