Patent ID: 7326786

Claim:
A compound of the formula: wherein R 1 is selected from lower alkyl, lower alkoxy, aryloxy lower alkyl, hydroxyl lower alkyl, lower alkoxy lower alkyl, and R 2 —(X) n —; X is selected from lower alkylene, hydroxy substituted lower alkylene, cyclo lower alkylene, aryl substituted lower alkylene, carboxy substituted lower alkylene, amido substituted lower alkylene, mono- or di-halo substituted lower alkylene, amino substituted lower alkylene, mono- or di-lower alkyl amino substituted lower alkylene and imido substituted lower alkylene; R 2 is is a carbon containing ring connected by a ring carbon atom, said ring being selected from an aryl ring, cycloalkyl ring containing from 3 to 6 carbon atoms, a 4 to 6 membered heterocycloalkyl ring containing from 3 to 5 carbon atoms and from 1 to 2 hetero atoms selected from oxygen, nitrogen and sulfur, and a 4 to 6 membered heteroaromatic ring containing from 1 to 2 hetero atoms selected from oxygen, sulfur and nitrogen; R 5 , R 6 and R 7 are independently selected from hydroxy, —SO 2 CH 3 , hydroxy-lower alkyl, amino, hydrogen, lower alkyl, halogen, lower alkoxy and mono- or di-lower alkyl amino, or when two of the substituents R 5 , R 6 and R 7 are substituted on adjacent carbon atoms on ring {circle around (P)}, these two substituents can be taken together with their adjacent, attached carbon atoms to form a group selected from an aryl ring, a 3 to 6 membered cycloalkyl ring, a 4 to 6 membered heterocycloalkyl ring or a 4 to 6 membered heteroaromatic ring with said heterocycloalkyl ring and said heteroaromatic ring containing from 1 to 2 hetero atoms selected from oxygen, nitrogen and sulfur, and n is an integer from 0 to 1; with the proviso that when {circle around (P)} is an aryl ring, then n is 1 and with the further proviso that when {circle around (P)} is an aryl ring, n is 1 and X is lower alkylene, then one of R 5 , R 6 and R 7 is other than hydrogen, halogen, or lower alkyl; and with the still further proviso that when {circle around (P)} is a cycloalkyl ring and n is 0, then one R 5 , R 6 and R 7 is other than hydrogen or lower alkyl; or N-oxides of compounds where R 2 contains a nitrogen in the heteroaromatic ring, sulfones where R 2 contains a sulfur in the heterocycloalkyl ring; or pharmaceutically acceptable salts thereof.