Patent ID: 7488728

Claim:
A compound of formula (I) wherein —X— is —S— or —O—; each R is independently selected from H or C 1 -C 4 alkyl; R 1 is H, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, halo, cyano, trifluoromethyl, trifluoromethoxy, —NR 3 R 4 , —CONR 3 R 4 , —COOR 3 or a group of the formula (i) R 2 is C 1 -C 4 alkyl, phenyl or phenyl substituted with 1, 2 or 3 substituents each independently selected from C 1 -C 4 alkyl, C 1 -C 4 alkoxy, nitro, hydroxy, cyano, halo, trifluoromethyl, trifluoromethoxy, benzyl, benzyloxy, —NR 6 R 7 , —CONR 6 R 7 , COOR 6 , —SO 2 NR 6 R 7 and —SO 2 R 6 ; R 5 is selected from H, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, carboxy, nitro, hydroxy, cyano, halo, trifluoromethyl, trifluoromethoxy, benzyl, benzyloxy, —NR 8 R 9 , —CONR 8 R 9 , —SO 2 NR 8 R 9 and —SO 2 R 8 ; R 3 , R 4 , R 6 , R 7 , R 8 and R 9 are each independently selected from H or C 1 -C 4 alkyl; and -Z- is a bond, —CH 2 —, or —O—; or a pharmaceutically acceptable salt thereof.