Patent ID: 8299111

Claim:
A compound of the formula wherein: R 1 is phenyl optionally independently substituted with 1 to 3 substituents chosen from C 1 -C 6 alkyl (which is optionally substituted with 1 to 3 halogen atoms), C 1 -C 6 cycloalkyl, C 1 -C 6 alkoxy (which is optionally substituted with 1 to 3 halogen atoms), C 1 -C 6 alkylthio, C 1 -C 6 alkylsulfonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkylamino, C 3 -C 6 cycloalkylamino, C 1 -C 6 dialkylamino, C 1 -C 6 alkylaminocarbonyl, acylamino, C 1 -C 6 dialkylaminocarbonyl, hydroxyl, halogen, cyano, nitro, oxo, heterocyclyl, aryl and heteroaryl; R 2 and R 3 are independently hydrogen or C 1 -C 6 alkyl; or R 2 and R 3 together with the carbon which they are attached to form a 3- to 6-membered cycloalkyl or heterocyclic ring; R 4 is hydrogen or methyl; R 5 is pyrazolyl optionally independently substituted with 1 to 3 substituents chosen from C 1 -C 6 alkyl (which is optionally substituted with 1 to 3 halogen atoms or with a heterocyclyl group), C 1 -C 6 alkoxy (which is optionally substituted with 1 to 3 halogen atoms), C 1 -C 6 cycloalkyl, heterocyclyl, phenoxy, halogen, cyano, dimethylaminoalkyl, phenyl (which is optionally substituted with 1 to 2 halogen atoms or C 1 -C 4 alkyl optionally substituted with halogen), thienyl (which is optionally substituted with 1 to 2 halogen atoms or C 1 -C 4 alkyl optionally substituted with halogen), and pyridinyl (which is optionally substituted with 1 to 2 C 1 -C 4 alkyl optionally substituted with halogen); wherein R 2 and R 3 , together with the carbon atom to which they are attached, do not form a cyclopropyl ring when R 5 is 1-phenyl 5-pyrazolyl, and R 1 is a phenyl, 4-chlorophenyl or 4-methylphenyl; or a tautomer or pharmaceutically acceptable salt thereof.