Patent ID: 8586627

Claim:
A method for treating a cancer or a benign tumor in a mammal, comprising administering to the mammal a therapeutically effective amount of the formula: W is (CHR 2 )n, O—(CHR 2 )n, S—(CHR 2 )n, or NR 2 —(CHR 2 )n, wherein the (CHR 2 )n portion of the W moiety can be fluorinated with anywhere from one fluorine atom to complete perflourination, X is O, CR 2 , or a bond between the two carbons to which it is attached, R 1 is H, C 1-8 alkyl phosphate, or dichloroacetate, R 2 is H, C 1-8 alkyl, or alkylaryl, or, when bonded to carbon, can be halo, n is an integer from 1-4, G is selected from the group consisting of C 1-6 alkyl, C 2-8 alkenyl, halo, —OR 1 , —NR 3 R 4 , —CF 3 , —CN, —NO 2 , —C 2 R 3 , —SR 3 , —N 3 , —C(═O)NR 3 R 4 , —NR 3 C(═O)R 3 , —C(═O)R 3 , —C(═O)OR 3 , —OC(═O)R 3 , —OC(═O)NR 3 R 4 , —NR 3 C(═O)OR 3 , —SO 2 R 3 , —SO 2 NR 3 R 4 , and —NR 3 SO 2 R 3 , where R 3 and R 4 are individually hydrogen, C 1-6 alkyl, or C 3-8 cycloalkyl, z is an integer of from 0-3, wherein only 0 or 1 of the X variables can be a bond between the two carbons to which it is attached, in an amount sufficient to induce apoptosis and/or inhibit angiogenesis, such that the growth of the tumor is at least partially inhibited, wherein the cancer is selected from the group consisting of melanoma, rectal carcinoma, colon carcinoma, breast carcinoma, ovarian carcinoma, small cell lung carcinoma, chronic lymphocytic carcinoma, esophageal carcinoma, prostate carcinoma, breast cancer, myeloma, and lymphoma, and the benign tumor is a hemangioma.