Patent ID: 7741371

Claim:
A method of binding an androgen receptor antagonist compound to an androgen receptor, comprising the step of contacting an androgen receptor compound of formula I: wherein X is a NH, or NR; Z is NO 2 , CN, COOH, COR, or CONHR; Y is CF 3 , F, I, Br, Cl, CN or Sn(R) 3 ; R is alkyl, haloalkyl, aryl, phenyl, halogen, alkenyl or OH; and Q is alkyl, halogen, N(R) 2 , NHCOCH 3 , NHCOCF 3 , NHCOR, NHCONHR, NHCOOR, OCONHR, CONHR, NHCSCH 3 , NHCSCF 3 , NHCSR, NHSO 2 CH 3 , NHSO 2 R, OR, COR, OCOR, OSO 2 R, SO 2 R or SR; and/or its isomer, pharmaceutically acceptable salt, or any combination thereof, in an amount effective to bind the androgen receptor compound to the androgen receptor.