Patent ID: 8071614

Claim:
A compound of formula (I): wherein represents a single or double bond, such that at least one bond within the 5 membered ring system is a double bond; Ring A may be optionally substituted by 1, 2 or 3 R a groups; B represents a â€”V-carbocyclic group or a â€”W-heterocyclyl group wherein said carbocyclic and heterocyclyl groups may be optionally substituted by 1, 2 or 3 R a groups; R e and R f independently represent hydrogen or C 1-6 alkyl; R a represents halogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl, â€”OR x , â€”Oâ€”(CH 2 ) n â€”OR x , haloC 1-6 alkyl, haloC 1-6 alkoxy, C 1-6 alkanol, â•O, â•S, nitro, Si(R x ) 4 , â€”(CH 2 ) s â€”CN, â€”Sâ€”R x , â€”SOâ€”R x , â€”SO 2 â€”R x , â€”COR x , â€”(CR x R y ) s â€”COOR z , â€”(CH 2 ) s â€”CONR x R y , â€”(CH 2 ) s â€”NR x R y , â€”(CH 2 ) s â€”NR x COR y , â€”(CH 2 ) s â€”NR x SO 2 â€”R y , â€”(CH 2 ) s â€”NHâ€”SO 2 â€”NR x R y , â€”OCONR x R y , â€”(CH 2 ) s â€”NR x CO 2 R y , â€”Oâ€”(CH 2 ) s â€”CR x R y â€”(CH 2 ) t â€”OR z or â€”(CH 2 ) s â€”SO 2 NR x R y groups; R x , R y and R z independently represent hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 alkanol, hydroxy, C 1-6 alkoxy, haloC 1-6 alkyl, â€”COâ€”(CH 2 ) n â€”C 1-6 alkoxy, C 3-8 cycloalkyl or C 3-8 cycloalkenyl; R 7 and R 8 independently represent hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl, aryl, heterocyclyl or R 7 and R 8 together with the nitrogen atom to which they are attached may form a nitrogen containing heterocyclyl ring, wherein said C 1-6 alkyl, aryl and heterocyclyl may be optionally substituted by 1, 2 or 3 R b groups; R 1 and R b independently represent an R a group or a â€”Y-carbocyclic or â€”Z-heterocyclyl group wherein said carbocyclic and heterocyclyl groups may be optionally substituted by 1, 2 or 3 R a groups; V and W independently represent a bond or a â€”(CR e R f ) n â€”group; Y and Z independently represent a bond, â€”COâ€”(CH 2 ) s â€”, â€”COOâ€”, â€”(CH 2 ) n â€”, â€”NR x â€”(CH 2 ) s â€”, â€”(CH 2 ) s â€”NR x â€”, â€”CONR x â€”, â€”NR x COâ€”, â€”SO 2 NR x â€”, â€”NR x SO 2 â€”, â€”NR x CONR y â€”, â€”NR x CSNR y â€”, â€”Oâ€”(CH 2 ) s â€”, â€”(CH 2 ) s â€”Oâ€”, Sâ€”, â€”SOâ€” or â€”(CH 2 ) s â€”SO 2 â€”; n represents an integer from 1-4; s and t independently represent an integer from 0-4; q represents an integer from 0-2; or a pharmaceutically acceptable salt thereof.