Patent ID: 8163740

Claim:
A compound of formula (I) wherein X is a bond, —NH—, —NH—S(O) 2 —, —NH—CH 2 —, —CH 2 —, —NH—C(O)—, —CH 2 —NH—C(O)—, —NH—C(O)—CH 2 —, —NH—C(O)—CH 2 —NH—, —NR a —C(O)—NR b —, or —NH—S(O) 2 —NH—; R 1 is halo; C 1-7 -alkyl, optionally substituted by OH, C 1-7 alkoxy or CN; C 1-7 -alkoxy; —NR a R b ; —C(NH 2 )N(OH); cyano; nitro; cycloalkyl; heterocycloalkyl; aryl; heteroaryl; or vinyl; wherein each of said cycloalkyl, heterocycloalkyl, aryl and heteroaryl is optionally substituted by one or more halo, cyano, nitro, C 1-7 -alkyl, C 1-7 -haloalkyl, C 1-7 -hydroxyalkyl, C 1-7 -cyanoalkyl, C 1-7 -alkoxy, C 1-7 -alkoxy-alkyl, —NR a R b , or 3- to 7-membered monocyclic cycloalkyl; and wherein said vinyl is optionally substituted by phenyl or a 5- or 6-membered monocyclic heteroaryl; Y is a bond, —CH 2 — or —CH 2 —CH 2 —O—; R 2 is cycloalkyl; heterocycloalkyl; aryl; heteroaryl; or 5- or 6-membered cycloalkyl or heterocycloalkyl, anellated with a benzo ring; wherein each of said cycloalkyl, heterocycloalkyl, aryl, heteroaryl, 5- or 6-membered cycloalkyl or heterocycloalkyl anellated with a benzo ring is optionally substituted by one or more halo, hydroxyl, C 1-7 -alkyl, C 1-7 -alkoxy, or 3- to 7-membered monocyclic cycloalkyl; and R a and R b are each independently hydrogen or C 1-7 -alkyl; or a pharmaceutically acceptable salt or ester thereof.