Patent ID: 8147666

Claim:
A crosslinked membrane structure, comprising: a sensing layer composition comprising a first polymer, an analyte responsive enzyme and a mediator; and a flux limiting membrane composition comprising a second polymer deposited over at least a portion of the sensing layer, wherein the flux limiting membrane composition comprises a crosslinker, and wherein the second polymer comprises the formula: wherein the solid horizontal line represents a polymer backbone; A is an alkyl substituted with a water-soluble constituent; D is a phenylalkyl group, a alkoxystyrene group, a hydroxyalkyl group, a alkoxyalkyl group, a alkoxycarbonylalkyl group, a a poly(ethylene glycol)-containing group, or a polyhydroxyl-containing group; and each of n, 1, p and q is independently a positive number wherein the crosslinker provides for intermolecular crosslinking between the first and second polymers.