Patent ID: 7196087

Claim:
A compound of the formula (I): or a pharmaceutically acceptable salt or prodrug thereof, wherein; Y is C; m is 1; n is 1; p is from 0 to 3; q is from 1 to 3; Z is —(CR a R b ) r — or —SO 2 —, where r is from 0 to 2 and each of R a and R b is independently hydrogen or alkyl; X is CH or N; each R 1 is independently halo, alkyl, haloalkyl, heteroalkyl, alkoxy, cyano, —S(O) 5 —R c , —C(═O)—NR c R d , —SO 2 —NR c R d , —N(R c )—C(═O)—R d , or —C(═O) R c , where s is from 0 to 2 and each of R c and R d is independently hydrogen or alkyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; A is —NR 3 — wherein R 3 is hydrogen, alkyl, acyl, amidoalkyl, hydroxyalkyl or alkoxyalkyl; each of R 4 and R 5 is independently hydrogen or alkyl, or R 4 and R 5 together with their shared carbon may form a carbocyclic ring of 3 to 6 members; and each of R 6 , R 7 , R 8 , R 9 and R 10 is independently hydrogen or alkyl, or one of R 6 and R 7 together wit R 10 and the atoms to which they are attached may form a heterocyclic ring of 3 to 7 members, or one of R 6 and R 7 together with one of R 8 and R 9 and the atoms to which they are attached may form a heterocyclic ring of 3 to 7 members.