Patent ID: 7452887

Claim:
A compound or Formula 1 or a pharmaceutically acceptable salt thereof, wherein: Ar is chosen from aryl, substituted aryl, heteroaryl, and substituted heteroaryl; A is —N— and B is —CH—, or A is —CH— and B is —N—; L is chosen from NR 1 and O; R 1 is chosen from H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, and substituted heterocycloalkyl; X and Y are independently chosen from CH and N; G is chosen from a covalent bond and NR 6 ; R 6 is chosen from hydrogen and optionally substituted alkyl; and R is chosen from optionally substituted heterocycloalkyl, with the proviso that when Ar is phenyl, A is —N—, B is —CH—, L is NR 1 , R 1 is H, X is CH, Y is CH, and G is a covalent bond, then R is not 4-methylpiperazin-1-yl.