Patent ID: 8921319

Claim:
A compound having the following formula or a pharmaceutically acceptable salt thereof; wherein R 2 is selected from the group consisting of: a branched, unbranched or cyclic alkyl group having 1 to 10 C atoms; a 5- or 6-membered heteroaromatic ring having 1-3 heteroatoms independently selected from N, S and O; an aryl group; a CH 2 group bearing a 5- or 6-membered heteroaromatic ring having 1-3 heteroatoms independently selected from N, S and O; and a CH 2 group bearing an aryl group; wherein said aryl group may have 6 or 10 C atoms, and wherein said heteroaromatic or aryl groups may be unsubstituted or substituted with 1 to 3 residues independently selected from the group consisting of —CH 2 NH 2 , —CN, —CF 3 , tetrazol-5-yl, F, Cl, Br, —CO 2 H, —CO 2 Me, —CO 2 Et, methyl, ethyl, propyl, and isopropyl; wherein Z and Z′ are independently selected from the group consisting of: wherein the values of m and n are independently in the range 0-3; and wherein L is selected from the group consisting of: wherein k is 1 or 2, Y and Y′ are independently selected from the group consisting of a covalent bond, —(CH 2 ) p —, —(CH 2 ) p O(OH 2 ) q —, —(CH 2 ) p NH(CH 2 ) q —, —(CH 2 ) p S(CH 2 ) q —, —(CH 2 ) p SS(OH 2 ) q —, (CH 2 ) p C(═O)(CH 2 ) q —, —(CH 2 ) p NHC(═O)(CH 2 ) q —, —(CH 2 ) p OC(═O)NH(CH 2 ) q —, —(CH 2 ) p OC(═O)(CH 2 ) q —, —(CH 2 ) p OC(═O)NH(CH 2 ) q —, —(CH 2 ) p NHC(═O)—O—(CH 2 ) q —, —(CH 2 ) p NHC(═O)NH(CH 2 ) q —, —(CH 2 ) p NHC(═NH)NH(CH 2 ) q —, and —(CH 2 ) p NHC(═O)(CH 2 ) q S—; and p and q independently range from 0 to 3.