Patent ID: 8796456

Claim:
A pharmaceutical composition comprising a compound that is of general formula (I) or is a salt, solvate, or prodrug thereof, wherein R 1 and R 2 are each independently divalent radicals selected from C 1-20 alkyl, C 2-20 alkenyl, C 7-20 alkaryl, C 2-10 alkynyl, C 7-20 aralkyl, C 2-20 heteroaralkyl, C 3-30 heterocyclylalkyl, C 3-30 alkylheterocyclyl, C 3-20 cycloalkyl, C 3-20 heterocyclyl, C 2-20 heteroaryl, C 5-20 aryl and C 1-10 alkoxy; R is H or A 2 X 4 ; wherein X 1 -X 4 are each independently selected from halo, OH, OR 3 , COH, NH 2 , NHR 3 , NR 3 R 4 , COOH, CONH 2 , COOR 3 , CONHR 3 , CONR 3 R 4 , SH, SR 3 , COR 3 and cyano, provided that at least one of groups X 1 -X 4 is a tertiary amine; wherein R 3 and R 4 are independently selected from C 1-6 alkyl, C 6-20 aryl, and C 7-20 aralkyl or R 3 and R 4 together with the nitrogen atom to which they are attached form a 3-8 membered ring, which is optionally substituted and optionally comprises other hetero atoms; A 1 and A 2 are each independently selected from NHR 5 ; wherein R 5 is a divalent radical selected from C 1-20 alkyl, C 6-20 aryl, C 7-20 alkaryl and C 7-20 aralkyl; wherein any of the groups R 1 -R 5 , A 1 and A 2 may be substituted with C 1-20 alkyl, C 2-20 alkenyl, C 7-20 alkaryl, C 2-10 alkynyl, C 7-20 aralkyl, C 2-20 heteroaralkyl, C 3-30 heterocyclylalkyl, C 3-30 alkylheterocyclyl, C 3-20 cycloalkyl, C 3-20 heterocyclyl, C 2-20 heteroaryl, C 5-20 aryl or C 1-10 alkoxy, halo, OH, OR 3 , COH, NH 2 , NHR 3 , NR 3 R 4 , COOH, CONH 2 , COOR 3 , CONHR 3 , CONR 3 R 4 , SH, SR 3 , COR 3 or cyano; and wherein the pharmaceutical composition also comprises a pharmaceutically acceptable carrier.