Patent ID: 8163530

Claim:
An attenuated recombinant respiratory syncitial virus (RSV) comprising; a RSV B strain 9320 backbone encoded by a polynucleotide comprising at least one artificially mutated nucleotide relative to SEQ ID NO: 1, or the complementary polynucleotide sequence thereof, wherein the mutated nucleotide comprises one or more of a deleted nucleotide, an inserted nucleotide, or a substituted nucleotide, and wherein the polynucleotide comprises; a) a polynucleotide sequence that is greater than 97.8% identical to SEQ ID NO: 1, as determined by Nucleotide-Nucleotide Basic Local Alignment Search Tool (BLASTN) using default parameters; or b) a polynucleotide sequence encoding an amino acid sequence or unique subsequence that is an amino acid sequence that is greater than 99.5% identical to SEQ ID NO: 9 or an amino acid sequence that is greater than 96.4% identical to SEQ ID NO: 10, as determined by Protein-Protein Basic Local Alignment Search Tool (BLASTP) using default parameters.