Patent ID: 7648999

Claim:
A compound of the formula (I): or a salt thereof, wherein: R 1 is phenyl, naphthyl, pyridyl, thienyl, furyl, quinolyl or benzothienyl optionally substituted with C 1-8 alkyl, C 1-8 alkyl having halogen, C 1-8 alkoxy, C 1-8 alkoxy having halogen, C 2-8 alkenyl, C 2-8 alkynyl, halogen, C 2-7 acyl, benzoyl, hydroxyl, nitro, amino, phenyl or pyridyl; R 2 is C 2-8 alkyl, C 1-8 alkyl having halogen, C 2-8 alkenyl, C 2-8 alkynyl, 3-7 membered cycloalkyl, C 1-8 alkyl having 3-7 membered cycloalkyl or C 1-6 alkyl substituted with phenyl, naphtyl or pyridyl, any of which is optionally substituted with C 1-8 alkyl, C 1-8 alkyl having halogen, C 1-8 alkoxy, C 1-8 alkoxy having halogen, C 2-8 alkenyl, C 2-8 alkynyl, halogen, C 2-7 acyl, benzoyl, hydroxyl, nitro, amino, phenyl or pyridyl; A is sulfur; X is a C 1-8 alkylene chain optionally substituted with C 1-8 alkyl, C 1-8 alkoxy or hydroxyl; Y is C(═O), C(═N—OR 10 ), CH(OR 11 ), CH═CH, C≡C, or C(═CH 2 ), in which each of R 10 and R 11 is halogen or C 1-8 alkyl; each of R 3 , R 4 and R 5 is hydrogen, C 1-8 alkyl, C 1-8 alkyl having halogen, C 1-8 alkoxy, C 1-8 alkoxy having halogen, C 2-8 alkenyl, C 2-8 alkynyl, halogen, C 2-7 acyl, benzoyl, hydroxyl, nitro, amino, phenyl, or pyridyl; B is CH; Z is oxygen or sulfur; each of R 6 and R 7 is hydrogen, C 1-8 alkyl, or C 1-8 alkyl having halogen; and R 8 is hydrogen or C 1-8 alkyl; provided that at least one of R 3 , R 4 and R 5 is not hydrogen.