Patent ID: 7385025

Claim:
A metallopeptide comprising a biologically active alpha-melanocyte stimulating hormone (α-MSH) sequence selected from the group consisting of Ac-Ser-Tyr-Ser-Nle-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2 (SEQ ID NO:1) and Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2 (SEQ ID NO:71), wherein an amino acid residue comprising a nitrogen atom and sulfur atom each available for complexation to a metal ion is inserted at any position from between the two and three position to the C-terminus position, with a rhenium or technetium metal ion complexed thereto to form an N 3 S 1 ligand, wherein any proline (Pro) residue which is either of the two residues on the immediately adjacent N-terminus side of the inserted residue comprising a nitrogen atom and sulfur atom available for complexation to a metal ion is substituted with Gly, Ala, Ser, Aib, 1-amino, 1-cyclopentane carboxylic acid or ΔAla.