Patent ID: 6844355

Claim:
A stereoisomerically purified form of a compound selected from the group consisting of quinine and quinidine, wherein the stereoisomerically purified form has different effects on cardiac ion channels and on gastric motility compared to the stereoisomerically unpurified form of the compound, wherein the stereoisomerically purified form of a compound is selected from the group consisting of: (1R)((2R,4R,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2R,4R,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2R,4S,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2R,4S,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2S,4R,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2S,4R,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2S,4S,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1R)((2S,4S,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2R,4R,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2R,4R,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2R,4S,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2R,4S,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2S,4R,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2S,4R,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2S,4S,8R)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; (1S)((2S,4S,8S)-8-vinylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol; and mixtures thereof.