Patent ID: 8653271

Claim:
A codrug comprising: (a) hydroxybupropion; and (b) an opioid antagonist or an opioid agonist selected from the group consisting of Naltrexone, Buprenorphine, Butorphanol, Codeine, Dihydrocodeine, Dihydromorphine, Ethylmorphine, Hydromorphone, Levallorphan, Levorphanol, Nalbuphine, Nalmefene, Nalorphine, Naloxone, 6-β-Naltrexol, Phenazocine, Pholcodine, and 6-α-Naltrexol; wherein hydroxybupropion is linked via a carbonate linker to the opioid antagonist or opioid agonist to form a single chemical entity.