Patent ID: 7935502

Claim:
An isolated nucleic acid comprising a nucleotide sequence encoding an immunoglobulin light chain variable region comprising the structure CDR L1 -CDR L2 -CDR L3 , wherein (i) CDR L1 comprises the amino acid sequence of SEQ ID NO. 18, (ii) CDR L2 comprises the amino acid sequence of SEQ ID NO. 19, and (iii) CDR L3 comprises the amino acid sequence of SEQ ID NO. 20; and an immunoglobulin heavy chain variable region comprising the structure CDR H1 -CDR H2 -CDR H3 , wherein (i) CDR H1 comprises the amino acid sequence of SEQ ID NO. 15, (ii) CDR H2 comprises the amino acid sequence of SEQ ID NO. 203, and (iii) CDR H3 comprises the amino acid sequence of SEQ ID NO. 17; wherein the immunoglobulin light chain variable region and the immunoglobulin heavy chain variable region together bind human hepatocyte growth factor (HGF).