Patent ID: 7297343

Claim:
A wound dressing comprising a polymeric film having complexed thereto by hydrophobic interaction a construct comprising a polyanion covalently bonded to a hydrophobic prosthetic moiety, with a first bioactive molecule directly complexed to the polyanion wherein the polyanion is a construct of Formula I: wherein R 1 is an C 1-18 alkyl or C 6-32 aryl group, each R 2 is independently selected from the group consisting of C 1-18 alkyl and C 6-32 aryl, R 3 is N or O, n is a number from 1 to 10, x is a number from 1 to about 30, and heparin is a heparin-activity molecule bonded to R 3 via a covalent bond, thereby forming a silyl-heparin covalent complex, with a first bioactive molecule directly complexed to the heparin-activity molecule.