Patent ID: 8440692

Claim:
A phosphate derivative of 2-aryl-4-quinolone having the following formula Ia, wherein R 2 ′, R 3 ′, R 4 ′, R 5 ′ and R 6 ′ independently are H, (CH 2 ) n CH 3 , (CH 2 ) n YH, Y(CH 2 ) n CH 3 , Y(CH 2 ) n YH, Y(CH 2 ) n NR 8 R 9 , X, (CH 2 ) n NR 8 R 9 , wherein n is an integer of 0-4, Y is O or S, X is F, Cl, or Br, and R 8 and R 9 independently are H, (CH 2 ) n YH, (CH 2 ) n N(C n H 2n+1 )(C m H 2m+1 ) or (CH 2 ) n CH 3 , wherein n and Y are defined as above, and m is an integer of 0-4; R 2 , R 3 , R 4 and R 5 independently are H, (CH 2 ) n CH 3 , (CH 2 ) n YH, Y(CH 2 ) n CH 3 , Y(CH 2 ) n YH, Y(CH 2 ) n NR 8 R 9 , X, (CH 2 ) n NR 8 R 9 , or R 3 and R 4 together is —Y(CH 2 ) n Y—, wherein n, Y, X, R 8 and R 9 are defined as above; and R 1 and R 1 ′ independently are H, Li + , Na + , K + , N + R 8 R 9 R 10 R 11 or benzyl wherein R 10 and R 11 independently are H, (CH 2 ) n YH, (CH 2 ) n N(C n H 2n+1 )(C m H 2m+1 ) or (CH 2 ) n CH 3 , n, m, Y, R 8 and R 9 are defined as above.