Patent ID: 7208616

Claim:
A process for preparing oxaliplatin, comprising (i) conducting a process of preparing cis-diiodo-(trans-L-1,2-cyclohexanediamine) Pt (II) complex comprising: a) combining trans-L-1,2-cyclohexanediamine of formula (5) with M 2 PtX 4 and KI to obtain a mixture; b) maintaining the mixture at room temperature; and c) recovering cis-diiodo-(trans-L-1,2-cyclohexanediamine) Pt (II) complex, wherein M is Li, Na or K, and wherein X is I, Cl or Br; (ii) reacting the cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex obtained in step c) with silver oxalate to obtain a reaction mixture; (iii) mixing the reaction mixture with KY to form oxaliplatin, wherein KY is KCl, KBr or KI; and (iv) recovering the oxaliplatin.