Patent ID: 7943745

Claim:
A human monoclonal antibody or a functional fragment thereof that binds CD98 and that has any, pair of sequences of the following (b) to (g) as a heavy chain variable region and a light chain variable region: (b) SEQ ID NOs: 41 and 47, (c) SEQ ID NOs: 43 and 47, (d) SEQ ID NOs: 43 and 77, (e) SEQ ID NOs: 43 and 79, (f) SEQ ID NOs: 43 and 81, and (g) SEQ ID NOs: 43 and 83, wherein said functional fragment is selected from the group consisting of Fab, Fab′, (Fab′)2, Fv, scFv, and sdFv of said antibody and a combination thereof.