Patent ID: 7741454

Claim:
A crosslinked high-molecular-weight product obtained by crosslinking a high-molecular-weight compound with a biological low-molecular-weight compound, the crosslinked high-molecular-weight product comprising a gel that is metabolized in vivo after application in vivo, wherein the high-molecular-weight compound is collagen, wherein the biological low-molecular-weight compound is obtained by modifying at least one carboxyl group of malic acid, oxalacetic acid, citric acid, cis-aconitic acid or 2-ketoglutaric acid with N-hydroxysuccinimide or N-hydroxysulfosuccinimide, wherein the crosslinked high-molecular-weight product has a water content of 96 to 98%, and wherein the crosslinked high-molecular-weight product has a chemical formula selected from the group consisting of: