Patent ID: 7091347

Claim:
A compound represented by Formula V: wherein: A is N; X is O, NR 3 or S, wherein R 3 is hydrogen, alkyl or aryl; and Y is a bond, O, NR′, C(═O), CH(OR′), CH(R′), or S(O) n , wherein n is 0, 1, or 2; and R′ is hydrogen or alkyl; R is aryl or heteroaryl; and L is R a —S(O) n1 , where R a is alkyl or aryl and n1 is 0, 1 or 2 wherein aryl is unsubstituted or substituted with 1, 2, or 3 substituents selected from the group alkyl, haloalkyl, halo, hydroxy, amino, haloalkoxy, cyano, nitro, heteroalkyl, methylenedioxy, ethylenedioxy, —Y-aryl, —Y-heteroaryl, —Y-cycloalkyl, —Y-heterocyclyl, —Y—OR p , —Y—NR p R q , —Y—C(O)—R p , —YS(O) 0-2 R p , —Y—N—S(O) 0-2 R p , —Y—S(O) 2 NR p R q , —Y—N—C(O)NR p R q , where Y is a bond or C 1 –C 3 alkylene, R p and R q are each independently selected from hydrogen, alkyl, haloalkyl, hydroxy, alkoxy, aryl, heteroaryl, cycloalkyl, and heterocyclyl, with the proviso that when the substituent is —YS(O) 1-2 R p or —Y—N—S(O) 2 R p said R p is not hydrogen; heteroalkyl is unsubstituted or substituted with 1 or 2 substituents selected from the group alkyl, haloalkyl, heteroalkyl, heterocyclyl, halo nitro, cyano, carboxy, acyl, —(alkylene) n —COOR, and —(alkylene) n —CONR a R b , where n is 0 or 1, R is hydrogen, alkyl, optionally substituted phenylalkyl, or optionally substituted heteroaralkyl, R a and R b are each independently hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, hydroxyalkyl, aryl, or R a and R b together with the nitrogen atom to which they are attached form heterocyclyl or heteroaryl.