Patent ID: 7759085

Claim:
A method for identifying a compound which binds to a 14189 polypeptide having kinase activity, comprising the steps of: a) contacting a purified 14189 polypeptide with a test compound; and b) determining whether the purified 14189 polypeptide binds to the test compound, wherein the purified 14189 polypeptide comprises a polypeptide selected from the group consisting of: i) the polypeptide encoded by the nucleotide sequence of SEQ ID NO:1, nucleotides 48-1682 of SEQ ID NO:1, or the cDNA insert of the plasmid deposited with ATCC as Accession Number PTA-2333, ii) a polypeptide having the amino acid sequence of SEQ ID NO:2, iii) a polypeptide comprising the serine kinase domain of 14189 (amino acid residues 13-304 of SEQ ID NO:2), iv) a polypeptide comprising the amino acid sequence shown in SEQ ID NO:2 and a non-kinase polypeptide, and v) a polypeptide comprising the serine kinase domain of 14189 (amino acid residues 13-304 of SEQ ID NO:2) and a non-kinase polypeptide, wherein the purified 14189 polypeptide is immobilized on a solid surface.