Patent ID: 8710076

Claim:
A compound of the formula Ia: wherein: B is isoquinoline; R 1a , R 1b and R 1c are independently selected from the group consisting of: (1) hydrogen, (2) halogen, (3) C 1-6 alkyl, (4) triazolyl, (5) oxazolyl, (6) pyrimidinyl, and (7) phenyl; R 2a , R 2b and R 2c are independently selected from the group consisting of: (1) hydrogen, (2) halogen, (3) C 1-6 alkyl, which is unsubstituted or substituted with halogen, (4) —O—C 1-6 alkyl, which is unsubstituted or substituted with halogen, and (5) —NH—C 1-6 alkyl, or —N(C 1-6 alkyl)(C 1-6 alkyl), which is unsubstituted or substituted with halogen; R 3 is C 1-6 alkyl; or a pharmaceutically acceptable salt thereof.