Patent ID: 8710073

Claim:
Compounds of general formula (I): in which: the cycle represents a 6-membered aromatic optionally comprising one or more nitrogen atoms, said nitrogen atom(s) optionally being substituted by an optionally substituted tetrahydrofuran group, such as 2-hydroxymethyl-tetrahydrofuran-3,4-diol; or by a —CH 2 -E group, wherein E represents an electron-attracting group such as —CONRR′; —CO—SR; —CO—Oalkyl; —CO—Oalkyl-OH; —O-alkyl-OAc; phenyl substituted for example by a CN or NO 2 group; wherein R and R′ are the same or different and independently represent a hydrogen atom or an alkyl group; and/or wherein said nitrogen atom(s) may be in the form of pyridinium salts, the counter ion being the anion of a halogen atom, such as bromide; represents a 5-to-10-membered mono- or bicyclic aryl group or heteroaryl group comprising one to three N atoms, substituted by one or more groups selected from the groups —OH; —(C 5 -C 20 )alkyl; —O(C 2 -C 20 )alkyl ; —S(O) p alkyl wherein p=0, 1 or 2 ; alkenyl; alkynyl; —Oalkenyl; —C(=)O-alkyl; —C(═O)-alkenyl; phenyl substituted by an alkyl group; cycloalkyl optionally substituted by an alkyl group, wherein is substituted in the ortho or meta position; R1 represents a hydrogen atom or an alkyl group and R2 and R3 together form an ═O group; or alternatively R3 represents an —OH or —Oalkyl group and R2 forms, together with R1, a single bond; the groups —C(═O)NHR1 and C(R3)(R2)- being understood to be located in two adjacent positions on the ring in the form of a base or an acid addition salt, as well as in the form of a pharmaceutically acceptable hydrate or solvate.