Patent ID: 8877171

Claim:
A pharmaceutical composition comprising a pharmaceutically acceptable carrier, and a conjugate of a sulfated polyol and a therapeutic effector molecule suitable for treating a disease selected from the group consisting of cancer, inflammation, autoimmune disease and fibrosis of the following formula P(OSO 3 − M + ) n (L-G-E) m , wherein P is a polyol macromolecule wherein a number n of the hydroxyl groups of the polyol macromolecule is substituted by sulfate groups OSO 3 − M + , n is a number >10, M is a cationic inorganic or organic counter ion to the anionic sulfate group, E is a therapeutic effector molecule suitable for treating a disease selected from the group consisting of cancer, inflammation, autoimmune disease and fibrosis, L is a linker or spacer between P and E, G is a reactive group suitable for the covalent attachment between L and E, and m is a number of from 1 to 100.