Patent ID: 6897319

Claim:
A compound selected from the Formula (I) or Formula (II): wherein A is selected from the group consisting of phenyl and naphthalenyl optionally substituted with 1 to 4 substituents; B is selected from heteroaryl optionally substituted on 1 to 4 available carbon atom ring members with a substituent selected from the group consisting of halogen, C 1-8 alkyl, C 1-8 alkoxy, hydroxy, hydroxy(C 1-8 )alkyl, hydroxy(C 1-8 )alkoxy, (halo) 1-3 (C 1-8 )alkyl and (halo) 1-3 (C 1-8 ) alkoxy; and, optionally substituted on available nitrogen atom ring members with a substituent selected from the group consisting of C 1-8 alkyl, C 2-8 alkenyl, hydroxy(C 1-8 )alkyl, (halo) 1-3 (C 1-8 )alkyl and oxido; Z is selected from the group consisting of oxo and hydroxy; R 1 is selected from the group consisting of: C 1-8 alkyl {wherein alkyl is optionally substituted on a terminal carbon with one substituent selected from the group consisting of C 1-8 alkoxy, —C(O)— (substituted with one substituent selected from the group consisting of H, OH, C 1-8 alkyl, C 1-8 alkoxy, NH 2 , —NH(C 1-8 )alkyl, —N((C 1-8 )alkyl) 2 ), —NHC(O)— (substituted with one substituent selected from the group consisting of H, OH, C 1-8 alkyl, C 1-8 alkoxy, NH 2 , —NH(C 1-8 )alkyl, —N((C 1-8 )alkyl) 2 ), —OC(O)— (substituted with one substituent selected from the group consisting of H, OH, C 1-8 alkyl, C 1-8 alkoxy, NH 2 , —NH(C 1-8 )alkyl, —N((C 1-8 )alkyl) 2 ), NH 2 , —NH(C 1-8 )alkyl, —N((C 1-8 )alkyl) 2 , —S(C 1-8 )alkyl, —SO 2 (C 1-8 )alkyl, cyano, (halo) 1-3 ; hydroxy and nitro}, cycloalkyl and aryl {wherein cycloalkyl and aryl are optionally substituted with 1 to 4 substituents independently selected from the group consisting of cyano, halo, hydroxy and nitro; and, wherein cycloalkyl and aryl are optionally substituted with one substituent selected from the group consisting of C 1-8 alkyl, (wherein alkyl is optionally substituted on a terminal carbon with one substituent selected from the group consisting of NH 2 , —NH(C 1-8 )alkyl, —N((C 1-8 )alkyl) 2 , cyano, (halo) 1-3 , hydroxy and nitro), C 1-8 alkoxy, NH 2 , —NH(C 1-8 )alkyl and —N((C 1-8 )alkyl) 2 }; R 2 and R 3 are independently selected from the group consisting of hydrogen, C 1-8 alkyl and halogen; or a pharmaceutically acceptable acid addition salt, a quaternary ammonium salt or a N-oxides thereof.