Patent ID: 8518972

Claim:
A compound of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: X is C═0 or CH 2 ; R 1 is —Y—R 3 ; R 2 is H or (C 1 -C 6 )alkyl; Y is: 6 to 10 membered aryl optionally substituted with one or more halogen; R 3 is: —(CH 2 ) n -aryl, —O—(CH 2 ) n -aryl or —(CH 2 ) n —O-aryl, wherein the aryl is optionally substituted with one or more: (C 1 -C 6 )alkyl, itself optionally substituted with one or more halogen; (C 1 -C 6 )alkoxy, itself substituted with one or more halogen; oxo; amino; carboxyl; cyano; hydroxyl; halogen; 6 to 10 membered aryl or heteroaryl, optionally substituted with one or more (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy or halogen; —CONH 2 ; or —COO—(C 1 -C 6 )alkyl, wherein the alkyl may be optionally substituted with one or more halogen; —(CH 2 ),-heterocycle, —O—(CH 2 ) n -heterocycle or —(CH 2 ) n , —O-heterocycle, wherein the heterocycle is optionally substituted with one or more: (C 1 -C 6 )alkyl, itself optionally substituted with one or more halogen; (C 1 -C 6 )alkoxy, itself substituted with one or more halogen; oxo; amino; carboxyl; cyano; hydroxyl; halogen; 6 to 10 membered aryl or heteroaryl, optionally substituted with one or more (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy or halogen; —CONH 2 ; or —COO—(C 1 -C 6 )alkyl, wherein the alkyl may be optionally substituted with one or more halogen; or —(CH 2 ) n -heteroaryl, —O—(CH 2 ) n -heteroaryl or —(CH 2 ) n —O-heteroaryl, wherein the heteroaryl is optionally substituted with one or more: (C 1 -C 6 )alkyl, itself optionally substituted with one or more halogen; (C 1 -C 6 )alkoxy, itself substituted with one or more halogen; oxo; amino; carboxyl; cyano; hydroxyl; halogen; 6 to 10 membered aryl or heteroaryl, optionally substituted with one or more (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy or halogen; —CONH 2 ; or —COO—(C 1 -C 6 )alkyl, wherein the alkyl may be optionally substituted with one or more halogen; and n is 0, 1, 2 or 3.