Patent ID: 8663678

Claim:
A solid dosage form for the ocular administration of an active principle, consisting of: a compressed powder mixture or compressed granulation, wherein said compressed powder mixture or compressed granulation comprises: a pharmacologically active substance, at least one of a disintegrating agent and a lubricating agent, said disintegrating agent being selected from the group consisting of sodium carboxymethylcellulose, croscarmellose sodium, crospovidone and povidone, and said lubricant being selected from the group consisting of sucroesters, polyethylene glycol, leucine and sodium borate, and at least one water-soluble excipient biocompatible with an ophthalmic use selected from the group consisting of carbohydrates, gums, sodium salts, calcium salts, magnesium salts, maltodextrins, hydroxyalkylcelluloses, carboxymethylcelluloses, chitosans, destructured starches, partially hydrolyzed starches, crosslinked starches, polyvinyl alcohols and acrylic acid polymers, said at least one water-soluble excipient is directly soluble or partially soluble in water, without passing through a gel state, wherein said compressed powder mixture or compressed granulation is obtained by a process selected from the group consisting of: direct compression, dry compression, wet compression, and compression of a lyophilisate, and the compression is carried out at a temperature of less than 45° C. and at a sufficient compression force so that said compression process in combination with said at least one water-soluble excipient confer onto said dosage form a disintegration time of less than two hours to release the active principle in the conjunctival cul-de-sac.