Patent ID: 6869967

Claim:
A compound of formula (I) wherein X is aryl, fluorenyl or heteroaryl each of which is optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy, cyano, amino, C 1-6 -alkylamino, C 1-6 -dialkylamino, C 3-6 -cycloalkylamino or carboxy; C 1-6 -alkyl, C 3-6 -cycloalkyl, C 2-6 -alkenyl, C 2-6 -alkynyl, C 1-6 -alkoxy, C 3-6 -cycloalkoxy, C 1-6 -alkylthio or C 3-6 -cycloalkylthio each of which is optionally substituted with halogen; and aryl, aryloxy, arylthio, acyl, aralkyl, aralkoxy, heteroaryl, heteroaralkyl, heteroaryloxy, heteroaralkoxy each of which is optionally substituted with halogen, perhalomethyl, perhalomethoxy or C 1-6 -alkyl; and wherein Y is aryl or heteroaryl each of which is optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy, cyano, amino, C 1-6 -alkylamino, C 1-6 -dialkylamino, C 3-6 -cycloalkyl amino, carboxy; C 1-6 -alkyl, C 3-6 -cycloalkyl, C 2-6 -alkenyl, C 2-6 -alkynyl, C 1-6 -alkoxy, C 3-6 -cycloalkoxy, C 1-6 -alkylthio or C 3-6 -cycloalkylthio each of which is optionally substituted with halogen; and aryl, aryloxy, arylthio, acyl, aralkyl, aralkoxy, heteroaryl, heteroaralkyl, heteroaryloxy, heteroaralkoxy each of which is optionally substituted with halogen, perhalomethyl or perhalomethoxy; or Y is C 1-6 -alkyl, C 3-6 cycloalkyl, C 2-6 -alkenyl, C 2-6 -alkynyl, or C 4-6 -alkenynyl; and Ar is arylene which is optionally substituted with one or more halogen; and Z is a O or S; and Q is —(CH 2 ) n — wherein n is 0, 1, 2 or 3; and R 1 in hydrogen or halogen; or R 1 is C 1-6 -alkyl, C 3-6 -cycloalkyl, C 1-6 -alkoxy, C 3-6 -cycloalkoxy each of which is optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy, carboxy, amino and cyano; and R 2 is hydrogen, C 1-6 -alkyl, C 3-6 -cycloalkyl, C 2-6 -alkenyl, C 2-6 -alkynyl, C 4-6 -alkenynyl or aryl; provided that X and Y independently is not a pyridine ring; provided that when X and Y are phenyl substituted with halogen, Ar is phenylene, O is (CH 2 ) n and n=0, then Z=S; or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, or any tautomeric forms, stereoisomers, mixture of stereoisomers racemic mixture, or polymorphs thereof.