Patent ID: 8334263

Claim:
A method for inducing an analgesic response to neuropathic pain in a mammal, excluding neuropathic cancer pain, said method comprising administering to the mammal, a composition comprising Flupirtine with the following structure or a pharmaceutically acceptable salt thereof, wherein flupirtine is administered in an amount of 0.5 mg/kg to about 20 mg/kg of body weight of the mammal in combination with an opioid selected from the list consisting of fentanyl, oxycodone, codeine, dihydrocodeine, dihydrocodeinone enol acetate, morphine, desomorphine, apomorphine, diamorphine, pethidine, methadone, dextropropoxyphene, pentazocine, dextromoramide, oxymorphone, hydromorphone, dihydromorphine, noscapine, papverine, papavereturn, alfentanil, and buprenorphine, in an amount effective to reduce the level of or to otherwise ameliorate the sensation of neuropathic pain, excluding topical administration.