Patent ID: 7304093

Claim:
A compound of the formula Ia: or a pharmaceutically acceptable salt or a mixture thereof, wherein (a) each occurrence of Z is CH 2 , wherein each occurrence of m is independently an integer ranging from 1 to 9; (b) G is (CH 2 ) x , where x is 2, 3, or 4; (c) W 1 and W 2 are independently L; (d) each occurrence of R 1 and R 2 is independently (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, phenyl, or benzyl (e) L is C(R 1 )(R 2 )—(CH 2 ) n —Y, where n is an independent integer ranging from 0 to 4; (f) each occurrence of Y is independently OH, COOH, CHO, (CH 2 ) n COOR 3 , SO 3 H, where (i) R 3 is (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, phenyl, or benzyl and is unsubstituted or substituted with one or more halo, OH, (C 1 -C 6 )alkoxy, or phenyl groups, (ii) each occurrence of R 6 is independently H, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, or (C 2 -C 6 )alkynyl and is unsubstituted or substituted with one or two halo, OH, C 1 -C 6 alkoxy, or phenyl groups; and (iii) each occurrence of R 7 is independently H, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, or (C 2 -C 6 )alkynyl; and provided that: (i) if x is 4, each occurrence of Z is CH 2 , each occurrence of m is 4, and W 1 is —CH(CH 3 )CO 2 H, then W 2 is not the same as W 1 ; (ii) if x is 4, each occurrence of Z is CH 2 , each occurrence of m is 2, and W 1 is —C(phenyl) 2 CH 2 CO 2 H, then W 2 is not the same as W 1 .