Patent ID: 8841304

Claim:
A compound of Formula I: or a stereoisomer or pharmaceutically acceptable salts thereof, wherein: G is cyclohexyl or phenyl optionally substituted by 1-3 independent R 4 groups, or when m is 0, G may additionally be absent or C 1 -C 4 alkyl; R 1 is —C(═O)OR a , —OR e , C 3 -C 6 cycloalkyl, 5 or 6 membered heteroaryl, phenyl or —O-phenyl, wherein the heteroaryl, phenyl or —O-phenyl may be optionally substituted with one or two R b groups; R 2 is hydrogen, CH 3 , or —NHC(═O)R f , R 3 is hydrogen or C 1 -C 3 alkyl; each R 4 is independently halogen, CF 3 , OCF 3 or CN; R 5 and R 6 are independently hydrogen or CH 3 ; R 7 and R 8 are independently hydrogen or C 1 -C 6 alkyl; R a is C 1 -C 4 alkyl; each R b group is independently halogen, CN, OCH 3 or C 1 -C 4 alkyl optionally substituted with halogen, OH, oxo, 5 or 6 membered heteroaryl or NR g R h ; R e is C 1 -C 4 alkyl substituted with OH or 5 or 6 membered heterocycle; R f is C 1 -C 4 alkyl optionally substituted with OH, a 5 or 6 membered heterocycle optionally substituted with one or two groups selected from the group consisting of oxo, halogen, CN, CF 3 and C 1 -C 3 alkyl, or a 5 or 6 membered heteroaryl optionally substituted with one or two groups selected from the group consisting of halogen, CN, CF 3 and C 1 -C 3 alkyl; R g and R h are independently hydrogen or C 1 -C 4 alkyl; m, n and p are independently 0 or 1; or R 5 is hydrogen, R 6 and R 7 together with the atoms to which they are attached form an optionally substituted 5-6 membered heterocyclic ring having one ring nitrogen atom, and R 8 is selected from the group consisting of hydrogen and C 1 -C 4 alkyl optionally substituted with OH or O(C 1 -C 3 alkyl) such that the compound of Formula I has the structure of Formula II: wherein R c and R d are independently hydrogen or C 1 -C 4 alkyl; and r is 1 or 2.