Patent ID: 7438906

Claim:
A. method of inhibiting IgE in a human subject comprising administering to the human subject a therapeutically effective amount of an anti-human CD23 antibody that (a) binds human CD23; (b) comprises the complementarity-determining regions CDR1, CDR2, and CDR3 of the light and heavy chains of antibody 6G5, wherein CDR1, CDR2, and CDR3 of the light chain of antibody 6 G5 consist of amino acids 23-36,52-58, and 91-100, respectively, of SEQ ID NO: 2; and CDR1, CDR2, and CDR3 of the heavy chain of antibody 6G5 consist of amino acids 31-36,51-67, and 100-111, respectively, of SEQ ID NO: 4; and (c) inhibits IL4-induced IgE production by B-cells.