Patent ID: 7621606

Claim:
A method for converting a bovine fibroblast or a human fibroblast into a cell of neuronal cell type, the method comprising:(a) culturing the bovine fibroblast or the human fibroblast in the presence of 0.1 to 10 μg/ml cytochalasin B, and optionally, at least one inhibitor of acetylation, at least one inhibitor of methylation, or a mixture thereof, wherein the culturing is in the absence of a cell permeablizing agent; (b) culturing the fibroblast in the presence of an agent or a condition that induces differentiation of a multipotent cell capable of differentiating into a neuronal cell type into a neuronal cell type wherein step (b) is performed after step (a); and (c) identifying the cell of neuronal cell type from the culture of step (a) and step (b).