Patent ID: 8114402

Claim:
An isolated fully human monoclonal antibody, wherein said monoclonal antibody has the following characteristics a) binds to an epitope in the extracellular domain of the matrix 2 ectodomain (M2e) polypeptide of an influenza A virus; b) binds to influenza A infected cells; and c) binds to influenza A virus, and wherein said antibody comprises a V H CDR1 comprising the amino acid sequence of SNYMS (SEQ ID NO: 103); a V H CDR2 region comprising amino acid sequence of VIYSGGSTYYADSVK (SEQ ID NO: 105), a V H CDR3 region comprising the amino acid sequence of CLSRMRGYGLDV (SEQ ID NO: 107); a V L CDR1 region comprising the amino acid sequence of RTSQSISSYLN (SEQ ID NO: 92); a V L CDR2 region comprising the amino acid sequence of AASSLQSGVPSRF (SEQ ID NO: 94); and a V L CDR3 region comprising the amino acid sequence of QQSYSMPA (SEQ ID NO: 96).