Patent ID: 7135164

Claim:
A gel composition for adjunct treatment of periodontitis, comprising: (i) antimicrobial extract obtained from Andrographis paniculata comprising andrographolide, deaxyandrographolide, 14-deoxy-11,12-didehydro-andrographolide, 14-deoxy-11-oxo-andographolide, 14-deoxy-11-dehydro-andrographolide, andographolide-19β-D glunoside, neoandrographolide, homo-andrographolide, andrographon, andrographan, andrographosterin, stimasterol, and peniculide, wherein the antimicrobial extract has antimicrobial or antibacterial activity against periodontal pathogens; and (ii) a gel base comprising a mixture of glyceryl monooleate and triglyceride; wherein the composition fonns a liquid crystal structure on contacting gingival fluid.