Patent ID: 8076480

Claim:
A process of preparing an optically active allyl compound represented by formula (III): wherein R 1 , R 3 , and R 4 each represent a hydrogen atom; R 2 and R 5 each represent a phenyl group; Nu represents a nucleophilic group selected from an α-ketocarbanion group, an amino group, and a substituted amino group; and the asterisk * indicates an asymmetric center, or an optically active allyl compound represented by formula (IV): wherein R 1 , R 2 , R 3 , R 4 , R 5 , Nu, and * are as defined above, or a mixture of the compound of formula (III) and the compound of formula (IV), the process comprising asymmetrically coupling an allyl compound represented by formula (I): wherein R 1 , R 2 , R 3 , R 4 , and R 5 are as defined above; and E represents a leaving group which is a carboxylic ester group, with an organic nucleophilic compound represented by formula (II): Nu-H (II) wherein Nu is as defined above, in the presence of a Pd complex compound catalyst having a quinoxaline derivative represented by formula (a) as a ligand: wherein * is as defined above.