Patent ID: 7713750

Claim:
A method for patterning one or more biomolecules on a substrate, the method comprising: coating the substrate with the one or more biomolecules; applying a focused laser onto the one or more biomolecules; and ablating a portion of the one or more biomolecules with the laser in a predetermined pattern, the predetermined pattern having one or more ablated portions and one or more non-ablated portions on the substrate, the one or more ablated portions having one or more predetermined ranges of biological function or activity from less than 100% functional or less than 100% active to 0% functional or 0% active or the one or more ablated portions having one or more predetermined ranges of biochemical function or activity from less than 100% functional or less than 100% active to 0% functional or 0% active, and the one or more non-ablated portions having one or more active or functional biomolecules of the one or more biomolecules on the substrate; and wherein one or more ablated portions having at least one dimension in the plane of the substrate from at least about 0.1 nanometer, at least about 1 nanometer, at least about 10 nanometers, at least about 100 nanometers, or at least about 250 nanometers to about 1 meter; and the one or more non-ablated portions having at least one dimension in the plane of the substrate from at least about 0.1 nanometer, at least about 1 nanometer, at least about 10 nanometers, at least about 100 nanometers, or at least about 250 nanometers to about 1 meter.