Patent ID: 8153087

Claim:
A method for purifying up to 100 mg of Radium (Ra) for target preparation for 225 Ac production from a radioactive source, the method comprising: a) determining the quality of the Radium material to be purified; b) contacting the radioactive source with a diluted mineral acid such that Radium is leached from the radioactive source into the diluted mineral acid to generate a leached pool; c) separating Radium from Al, Mg, Co, Ni, Zn and Fe in the leached pool with an acidic macroporous type cation exchange resin having about 35% porosity to generate a first set of one or more Radium containing fractions, d) separating Radium from Ba, Sr, and Pb in the first set of one or more Radium containing fractions by extraction chromatography with an Sr Resin to generate a second set of one or more Radium containing fractions; e) pooling the Radium containing fractions generated in step d); and f) concentrating the pooled Ra-containing fractions to generate purified Ra-containing fractions.