Patent ID: 7645770

Claim:
A pharmaceutically acceptable salt of the compound of formula (1): or a enantiomer, diastereomer, or geometric isomer thereof, wherein R 1 is a group Ar 1 L 2 Ar 2 Alk- in which: Ar 1 is [2,7]naphthyridin; L 2 is a covalent bond or a linker atom or group selected from —O— or —S— atoms or —C(O)—, —C(O)O—, —OC(O)—, —C(S)—, —S(O)—, —S(O) 2 —, —N(R 8 )—-CON(R 8 )—, —OC(O)N(R 8 )—, —CSN(R 8 )—, —N(R 8 )CO—, —N(R 8 )C(O)O—, —N(R 8 )CS—, —S(O) 2 N(R 8 )—, —N(R 8 )S(O) 2 —, —N(R 8 )O—, —ON(R 8 )—, —N(R 8 )N(R 8 )—, —N(R 8 )CON(R 8 )—, —N(R 8 )CSN(R 8 )—, and —N(R 8 )SO 2 N(R 8 )—, wherein R 8 is a hydrogen atom or an optionally substituted straight or branched C 1-8 alkyl group and wherein when the linker group contains two R 8 substituents, these are the same or different; Ar 2 is an optionally substituted arylene or heteroarylene group; Alk is a chain —CH 2 —CH(R)—, —CH═C(R)— or —CH —CH 2 R in which R is CO 2 Alk 7 , wherein Alk 7 is methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, s-butyl, t-butyl, pentyl or neopentyl; X is an —O— or —S— atom or —N(R 2 )— group in which: R 2 is a hydrogen atom or a C 1-8 alkyl group; V is an oxygen (O) or sulphur (S) atom; or R z is an atom selected from hydrogen and halogen and R x and R y are joined together to form an optionally substituted spiro linked cycloaliphatic group selected from cyclopentyl, cyclohexyl, cycloheptyl, and cyclooctyl; and N-oxides thereof.