Patent ID: 7223605

Claim:
A method comprising steps of: acquiring mass spectral data from a sample derived from a dry blood spot on filter paper, wherein said data includes values comprised of a citrulline concentration (cit) and optionally a citrulline concentration after an mrm scan (cit[mrm]); comparing said values, respectively, with a cit flag threshold and optionally a cit[mrm] flag threshold; identifying whether or not there is an elevation of any of said values above any of said flag thresholds; interpreting said sample as being normal for citrullinemia, provided there is no said elevation of any of said values; and flagging the sample for re-analysis provided any of the following occur: i. said cit is greater than said cit flag threshold; or ii. said cit(mrm) is greater than said cit(mrm) flag threshold.