Patent ID: 7378082

Claim:
A method for treating allergic rhinitis without causing an adverse effect of bitter taste in a subject, comprising the steps of: identifying a subject suffering from allergic rhinitis; administering to the nose of the subject one to two sprays at 50-115 μL per nostril per spray once or twice daily of an aqueous epinastine formulation; wherein said aqueous epinastine formulation consists essentially of (a) about 0.1% (w/v) of epinastine or an acid addition salt thereof, (b) 0.05-0.5% (w/v) of hydroxypropylmethylcellulose to maintain the viscosity between 1.5-10 centipoise, (c)1-2% (w/v) of propylene glycol, and (d) a buffer to maintain the pH between 5-8, said aqueous epinastine formulation has a tonicity between 200-400 mOsm/kG, said formulation does not contain a sweetening agent; whereby the subject perceives a minimal or no bitter taste and the symptoms of allergic rhinitis are reduced.