Patent ID: 7622487

Claim:
A compound represented by the formula: wherein Ar is a phenyl group optionally having 1 to 4 substituents selected from (A) a halogen atom, (B) a C 1-6 alkyl group, and (C) a 5- or 6-membered aromatic heterocyclic group having 1 to 4 hetero atoms of one or two kinds selected from a nitrogen atom, an oxygen atom and a sulfur atom in addition to carbon atoms, R 1 is an acyl group represented by the formula: —(C═O)—Ra, wherein Ra is (A) a hydrogen atom, or (B) (a) a C 1-6 alkyl group, or (b) a 5- or 6-membered aromatic or 4- to 6-membered non-aromatic heterocyclic group having 1 to 4 hetero atoms of one or two kinds selected from a nitrogen atom, an oxygen atom and a sulfur atom in addition to carbon atoms, each of which optionally has 1 or 2 substituents selected from (i) a halogen atom, (ii) a C 1-6 alkyl group optionally substituted with a 5- or 6-membered aromatic or non-aromatic heterocyclic group having 1 to 4 hetero atoms of one or two kinds selected from a nitrogen atom, an oxygen atom and a sulfur atom in addition to carbon atoms, a C 1-6 alkanoyl group, or a C 6-14 aryl-carbonyl group, (iii) a C 1-6 alkoxy group, (iv) an amino group, (v) a mono- or di-C 1-6 alkylamino group, (vi) a C 1-6 alkanoylamino group, (vii) a N—C 1-6 alkyl-N ′ —C 1-6 alkanoylamino group, (viii) a C 1-6 alkoxy-carbonyl group, (ix) a C 1-6 alkanoyl group optionally substituted with C 1-6 alkoxy, mono- or di-C 1-6 alkylamino, halogeno C 1-6 alkyl or a halogen atom, (x) a C 6-14 aryl-carbonyl group, (xi) a C 7-19 aralkyl-carbonyl group, (xii) a C 3-6 cycloalkyl-carbonyl group, (xiii) a 5- or 6-membered aromatic or non-aromatic heterocyclic-carbonyl group having 1 to 4 hetero atoms of one or two kinds selected from a nitrogen atom, an oxygen atom and a sulfur atom in addition to carbon atoms, (xiv) a hydroxy group, (xv) a C 7-19 aralkyloxy group, (xvi) a C 3-6 cycloalkyloxy group, (xvii) a C 1-6 alkoxy-C 1-6 alkoxy group, (xviii) a carbamoyl group, (xix) a mono- or di-C 1-6 alkylcarbamoyl group, (xx) a C 1-6 alkylsulfonyl group, (xxi) a mono- or di-C 1-6 alkylaminosulfonyl group, (xxii) a formyl group, (xxiii) a formylamino group, (xxiv) an oxo group, and (xxv) a 5- or 6-membered aromatic or non-aromatic heterocyclic group having 1 to 4 hetero atoms of one or two kinds selected from a nitrogen atom, an oxygen atom and a sulfur atom in addition to carbon atoms, which optionally has 1 or 2 substituents selected from C 1-6 alkanoyl and C 1-6 alkoxy-C 1-6 alkanoyl, X is an imino group, Z is a methylene group, Ring A is a piperidine ring, and Ring B is a phenyl group substituted with a C 1-6 alkoxy group and a tetrazolyl group substituted with a halogenated C 1-6 alkyl group, or a salt thereof.