Patent ID: 8906602

Claim:
A method for identifying a compound that reduces production of a 4-hydroxy-2-alkylquinoline (HAQ) molecule, 4-hydroxy-2-heptylquinoline (HHQ) molecule, or a derivative or precursor thereof, said method comprising: (a) contacting a Pseudomonas cell with a compound; (b) measuring the production of a molecule selected from the group consisting of a HAQ molecule, HHQ molecule, or a derivative or precursor thereof in said Pseudomonas cell; and (c) comparing the production of said molecule in step (b) relative to production of said molecule by said Pseudomonas cell when not contacted with said compound, thereby identifying said compound tha reduces production of said HAQ molecule, HHQ molecule, or a derivative or precursor thereof, wherein said HAQ molecule, said HHQ molecule, or said derivative or precursor thereof is selected from any one of the following: wherein R 1 , R 2 , and R 4 are independently —C 5 H 11 , —C 6 H 13 , —C 7 H 15 , —C 8 H 17 , —C 9 H 19 , —C 11 H 23 , —C 7 H 13 , —C 8 H 15 , —C 9 H 17 , or —C 11 H 21 ; R 3 is —C 5 H 11 , —C 6 H 13 , —C 7 H 15 , —C 8 H 17 , —C 9 H 19 , —C 11 H 23 , —C 9 H 17 , or —C 11 H 21 ; R 5 is —C 5 H 11 , —C 6 H 13 , —C 7 H 15 , —C 8 17 , —C 9 H 19 , or —C 11 H 23 .