Patent ID: 7321040

Claim:
A compound of the formula wherein the molecular weight of the compound of formula I is less than 1000 AMU; X is >CH 2 >NH, sulfur, >S═O, >SO 2 or oxygen; R 1 is selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl; R 2 is selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl; s is an integer from 0-4; R 3 is R 4 , R 5 —(NR 6 )—, R 5 —S—, R 5 —(S═O)—, R 5 —(SO 2 )—, R 5 —SO 2 —NR 6 —, R 5 —(NR 6 )—SO 2 —, R 5 —O—, R 5 —(C═O)—, R 5 —(NR 6 )—(C═O)—, R 5 —(C═O)—NR 6 —, R 5 —O—(C═O)—, R 5 —(C═O)—O—, R 5 —CR 7 ═CR 8 — or R 5 —C≡C—; such that the molecular weight of R 3 is less than 500 AMU; R 4 , R 5 and R 6 are each selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl; wherein the molecular weight of the compound of formula I is less than 1000 AMU; or a pharmaceutically acceptable salt thereof.