Patent ID: 8450494

Claim:
Compounds having the structure of Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable enantiomers, diastereomers, wherein R 1 and R 3 are independently selected from halo, cyano, or optionally substituted groups selected from amino, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, aryl, cycloalkyl, carbocycle, heterocycloalkyl, cycloalkyl(C 1-6 )alkyl, or heterocycloalkyl(C 1-6 )alkyl groups; n=0, 1, 2; m =0,1,2,3; & p=0,1,2,3,4; R 2 at each occurrence is independently selected from halo, amino, cyano, nitro, (C 1-4 )alkyl, (C 2-6 )alkenyl, (C 2-6 )alkynyl, —(CH 2 ) n COO(C 1-4 )alkyl, —(CH 2 ) n COOH, S(O) n , S(O) n NH 2 , or S(O) n NH(C 1-6 )alkyl; q=0, 1, 2; and R a & R b at each occurrence is independently selected from halo, cyano, nitro, hydroxyl, or optionally substituted groups selected from alkoxy, perfluoroalkoxy, amino, C 1-4 alkyl, C 2 - 6 alkenyl, C 2-6 alkynyl, cycloalkyl, —(CH 2 ) n COO(C 1-4 )alkyl, or —(CH 2 ) n COOH groups, wherein the groups representing R 1 , R 2 , R 3 , and R a and R b may be further substituted on available carbon atom with one or three substituent(s).