Patent ID: 7176195

Claim:
A compound according to formula 1 or 2, or a tautomer or a pharmaceutically acceptable salt thereof: wherein: W is either N or C—R 4 ; R 1 –R 4 are independently selected from H, F, Cl, Br, alkyl, CF 3 , phenyl, OH, O-alkyl, NH 2 , NH-alkyl, N(alkyl) 2 , NO 2 and CN, or R 2 and R 3 together can be —CH═CH—CH═CH—; G 1 is a bicyclic fused azepine derivative according to formula 8: in which A 16 and A 17 are both CH 2 , or one of A 16 and A 17 is CH 2 and the other is selected from CH(OH), CF 2 , O, SO a and NR 5 ; R 5 is selected from H, alkyl, CO-alkyl and (CH 2 ) b R 6 ; R 6 is selected from phenyl, pyridyl, OH, O-alkyl, NH 2 , NH-alkyl, N(alkyl) 2 , NO 2 , CO 2 H and CN; a is 0, 1 or 2; b is 1, 2, 3 or 4; Y is CH or N; Z is CH═CH or S; and G 2 is a group according to formula 9: in which Ar is selected from phenyl, pyridyl, naphthyl and mono- or polysubstituted phenyl or pyridyl wherein the substituents are selected from F, Cl, Br, alkyl, OH, O-alkyl, NH 2 , NH-alkyl, N(alkyl) 2 , NO 2 and CN; V is O, N—CN or S; c is 0 or 1; d is 0 or 1; and e is 0 or 1, provided that d and e are not both 0.