Patent ID: 8158612

Claim:
A method of treating undesired angiogenesis in a human or animal comprising administering to the human or animal having undesired angiogenesis an effective angiogenesis treating amount of a compound having the formula wherein R a is selected from —OCH 3 , —OCH 2 CH 3 or —CCCH 3 ; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons; and wherein the undesired angiogenesis is associated with atherosclerosis, abnormal would healing, inflammatory disorders, psoriasis, diabetic retinopathy, retinopathy of prematurity (retrolental fibroplastic), macular degeneration, corneal graft rejection, neovascular glaucoma or Osler Weber syndrome (Osler-Weber-Rendu disease).