Patent ID: 8765723

Claim:
A method of treating a disease selected from diabetic mellitus complications, intimal proliferation, restenosis, intracranial arterial stenosis, recurrent strokes, cerebral infarction, cerebrovascular disorders, arthrosclerosis, atherothrombosis complications, peripheral vascular disease, Reynaud's Disease, sexual dysfunction, ulcers, cerebral circulation impairment, thrombolytic disorders, inflammation, hypotension, asthma, ischemic heart disease, coronary heart disease and acute coronary syndrome, in a patient in need thereof, comprising the step of administering to the patient a pyrogen-free pharmaceutical composition comprising a compound of Formula II: wherein: each Y is independently selected from hydrogen and deuterium; and Q is —CH 2 CH 2 — or —CH═CH—, wherein one or more of the hydrogen atoms in Q is optionally replaced by deuterium.