Patent ID: 7456203

Claim:
A compound of the formula: wherein L b is a group of formula (i) or (j): wherein: R 46 is alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, or heterocycle; R 47 is alkyl, substituted alkyl, aryl, acyl, heterocycle, or —COOR 49 where R 49 is alkyl; or R 46 and R 47 together with the nitrogen atom to which they are attached form a heterocycle; R 48 is a covalent bond that attaches (i) or (j) to X; R 49 is alkyl; and X is a group of the formula: —X a -Z-(Y a -Z) m -Y b -Z-X a — wherein m is 1; x a at each separate occurrence is a covalent bond; Z at the first and third occurrence is alkylene; Z at the second occurrence is selected from the group consisting of alkylene, substituted alkylene, alkenylene, substituted alkenylene, alkynylene, and substituted alicynylene; Y a and Y b at each separate occurrence are selected from the group consisting of a covalent bond, —O—, —C(O)—, —OC(O)—, —C(O)O—, —NR—, —S(O) n —, —C(O)NR′—, —NR′C(O)—, —NR′C(O)NR′—, —NR′C(S)NR′—, —C(=NR′)NR′—, —NR′C(=NR′)—, —OC(O)NR′—, —NR′C(O)O—, —P(O)(OR′)O—, —OP(O)(OR′)—, —S(O) n CR′R″—, —S(O) n NR′—, —NR′S(O) n —and —S—S—; n is 0, 1 or 2; and R, R′ and R″ at each separate occurrence are selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, cycloalkenyl, substituted cycloalkenyl, alkynyl, substituted alkynyl, aryl, heteroaryl and heterocyclic; or a pharmaceutically-acceptable salt thereof.