Patent ID: 8507001

Claim:
A method for reducing or retarding burst release of a drug from a dosage form that has been tampered with comprising providing a dosage form comprising a drug and a TPTA (Tamper Prone Therapeutic Agent) trap, wherein the dosage form comprises a multiplicity of subunits and/or layers, and wherein the drug and the TPTA trap are maintained separately in different subunits or layers of the dosage form, and wherein if the TPTA trap comprises a gelling agent, the TPTA trap comprises a TPTA trap activator and, either (a) the gelling agent and the TPTA trap activator are sequestered from each other within the dosage form or (b) the gelling agent and the TPTA trap activator are not sequestered from each other and the gelling agent is in a gelled state within the dosage form.