Patent ID: 8435982

Claim:
A pharmaceutical composition for oral administration comprising: a therapeutically effective quantity of insoluble or practically insoluble in water lipophilic active ingredient or a pharmaceutically acceptable salt thereof; wherein the lipophilic active ingredient comprises a non-steroidal anti-inflammatory drug or a pharmaceutically acceptable salt thereof; an effective amount of milk as a solubilizing/dispersing agent to enhance bioavailability and/or improve solubility; and an alkaline buffer with a nominal pH value from 11 to 12 which is selected from the group consisting of NaH 2 PO 4 /NaOH 0.2M, NaH 2 PO 4 /NaOH 0.01M, KH 2 PO 4 /KOH 0.2M and Glycine/NaOH 0.05M; wherein a solution of said active ingredient with said alkaline buffer with a nominal pH value from 11 to 12 is formed and an appropriate volume of said solution containing the therapeutic dose of the active ingredient is dispersed in a volume of milk between 20 and 500 mL and subsequently is gently agitated prior to oral administration.