Patent ID: 7855060

Claim:
A method for producing an L-amino acid, comprising: cultivating an L-amino acid producing Escherichia coli in a medium to produce and excrete said L-amino acid into the medium in an amount of at least 0.5 g/L, and collecting said L-amino acid from the medium; wherein the Escherichia coli has been modified to attenuate expression of a gene selected from the group consisting of yoeB, yafQ, mazF, relE, yeeV, hipA, and combinations thereof, wherein said gene(s) encodes a toxin of a bacterial toxin-antitoxin pair, wherein said expression is attenuated by a method selected from the group consisting of a) introducing an insertion and/or deletion that disrupts said gene(s), b) replacing one or more bases of the gene(s), c) modifying an expression regulating sequence of the gene(s), and d) combinations thereof.