Patent ID: 7153861

Claim:
A compound of the formula (IB): in which: R a and R b together with the pyrimidine ring carbon atoms to which they are attached form a fused 5-membered carbocyclic ring; R 2 is phenyl, substituted by one to three fluorine atoms; R 3 is methyl or C (1-3) alkyl substituted by NR 8 R 9 ; or R 3 is Het-C (0-2) alkyl in which Het is a 5- to 7- membered heterocyclyl ring having N and in which N is unsubstituted or substituted by C (1-6) alkyl; R 4 and R 5 together form a 4-(4-trifluoromethylphenyl)phenyl moiety; R 8 and R 9 which may be the same or different are selected from the group consisting of hydrogen, or C (1-6) alkyl); X is S, or a pharmaceutically acceptable salt thereof; excluding the compound 1-(N-(2-(diethylamino)ethyl)-N-(4-(4-trifluoromethylphenyl)benzyl)aminocarbonylmethyl)-2-(4-fluorobenzyl)thio-5,6-trimethylenepyrimidin-4-one, and pharmaceutically acceptable salts thereof.