Patent ID: 8178667

Claim:
A compound of formula (I): and pharmaceutically acceptable salts thereof, and enantiomers and diastereomers thereof, wherein R 1 is selected from the group consisting of (1) hydrogen, (2) —C 1-6 alkyl, and wherein said R 1 alkyl moiety is optionally substituted with one or more (a) halogen, (b) cyano, and (c) —O—C 1-6 alkyl, wherein said alkyl is optionally substituted with one or more halo; R 2 , R 3 , R 4 and R 5 are independently selected from the group consisting of (1) hydrogen, (2) —C 1-6 alkyl, (3) halogen, wherein said R 2 , R 3 , R 4 and R 5 alkyl is optionally substituted with one or more (a) halogen, (b) hydroxy, and (c) —O—C 1-6 alkyl; provided that when R 2 is hydrogen and R 3 is fluorine then R 4 cannot be chlorine; R 6 , R 7 , R 8 and R 9 are independently selected from the group consisting of (1) hydrogen, and (2) halogen; HET is selected from the group consisting of wherein X 1 , X 2 , X 3 , X 4 and X 5 together form a 5- or 6-membered aromatic ring, wherein each of X 1 , X 2 , X 3 , X 4 and X 5 is independently selected from the group consisting of (1) CR 12 , (2) N, (3) NR 13 , (4) O, and (5) S, provided that X 4 may alternatively be a bond, and further provided that two R 12 groups, or one R 12 group and one R 13 group, when positioned at neighboring X atoms on the ring, may be linked together to form a group selected from (1) —O—CH 2 —CH 2 —O—, (2) —CR 14 ═CR 14 —CR 14 ═CR 14 —, and (3) —NR 15 —CR 14 ═CR 14 —, or wherein X 6 is selected from the group consisting of (1) CR 14 R 14′ , (2) NR 15 , and (3) O; provided that when p is O, X 6 is CR 14 R 14′ ; R 12 are selected from the group consisting of (1) hydrogen, (2) C 1-6 alkyl, (3) —O—C 1-6 alkyl, (4) cyano, (5) halogen, and (6) —(CH 2 ) m -aryl, wherein said R 12 alkyl or aryl moiety is optionally substituted with one or more (a) halogen, (b) cyano, (c) —C 1-6 alkyl, and (d) —O—C 1-6 alkyl, wherein said alkyl moiety is optionally substituted with one or more halo; R 13 is selected from the group consisting of (1) hydrogen, (2) —C 1-6 alkyl, wherein said alkyl and cycloalkyl R 13 moiety is optionally substituted with one or more (a) halogen, (b) cyano, or (c) hydroxy; R 14 and R 14′ are independently selected from the same group as R 12 and R 12′ ; R 15 is selected from the same group as R 13 ; m is 1, 2, 3 or 4; and p is 0, 1 or 2.