Patent ID: 7803568

Claim:
A method for preparing a surface for use as a biosensor, comprising: forming a carbodithioate ligand by mixing CS 2 with a nucleophile represented by formula NHR 1 R 2 in the presence of a solvent selected from the group consisting of methanol, ethanol, n-propyl alcohol, isopropyl alcohol, water, toluene, dichloromethane, dichlorobenzene and combination thereof and immersing the surface in the mixture to cause the carbodithioate ligand to bond thereto, the surface being selected from at least one of a Group 13 metal, a Group 14 metal, a Group 15 metal, iron oxide, cadmium selenide, cadmium sulfide, indium tin oxide and gold; wherein the formed carbodithioate ligand is represented by the structure R 1 R 2 N—CS 2 ; wherein R 1 and R 2 are independently selected from —H, alkyl, acyl, aryl, heteroaryl, —OR 3 , —NR 4 R 5 , SiR 6 R 7 R 8 or SR 9 ; R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently selected from —H, alkyl, acyl, aryl, or heteroaryl; and R 9 is aryl or heteroaryl.