Patent ID: 7718426

Claim:
A composition comprising a hair dermal papilla cell preparation and epidermal cells, wherein the hair dermal cell preparation is prepared by a method comprising: (a) providing a skin tissue; (b) removing epidermal tissue from the skin tissue, thereby producing a dermal tissue fraction; (c) subjecting the dermal tissue fraction to collagenase treatment, thereby producing a cell suspension comprising hair dermal papilla cells; and (d) cryopreserving the cell suspension to kill follicular epidermal cells present in the cell suspension, thereby producing the hair dermal papilla cell preparation; wherein the composition is prepared by mixing the hair dermal papilla cell preparation with an amount of active epidermal cells to obtain a ratio of the number of hair dermal papilla cells to the number of active epidermal cells from 1:10 to 10:1, thereby producing the composition; and wherein the hair dermal papilla cells and the active epidermal cells are each obtained from a mammal selected from the group consisting of a mouse, a rat, and a human.