Patent ID: 7002019

Claim:
A method of synthesizing aromatic ketone compositions of formula I: wherein: R 1 may be hydrogen or can be selected from the group consisting of (C 1 -C 6 )-alkyl and (C 3 -C 7 )-cycloalkyl, and wherein the alkyl group can be substituted by (C 3 -C 7 )-cycloalkyl or can be mono- or polysubstituted by an aryl group, wherein the aryl group can be mono- or polysubstituted by halogen, (C 1 -C 6 )-alkyl, (C 3 -C 7 )-cycloalkyl, hydroxy and nitro groups; R 1 may be an aryl group, wherein the aryl group can be mono- or polysubstituted by halogen, (C 1 -C 6 )-alkyl, (C 3 -C 7 )-cycloalkyl, hydroxy and nitro groups; R 1 may further be a protecting group; R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 may be the same or different and are each selected from the group consisting of hydrogen, (C 1 -C 6 )-alkyl, (C 3 -C 7 )-cycloalkyl, (C 1 -C 6 )-acyl, (C 1 -C 6 )-alkoxy, alkoxycarbonyl (COOR 1 ), halogen, benzyloxy, the nitro group, the amino group, the (C 1 -C 4 )-mono or dialkyl-substituted amino group, or an aryl group, wherein the aryl group can be mono- or polysubstituted by halogen, (C 1 -C 6 )-alkyl, (C 3 -C 7 )-cycloalkyl, hydroxy and nitro groups; X and Z may be the same or different and are each selected from the group consisting of O, S and NH; comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of a compound of the formula II: wherein the stereochemical centers may have R or S configuration.