Patent ID: 7875730

Claim:
A process for the manufacture of Carvedilol comprising the steps of : a) reacting 4-(oxiran-2-ylmethoxy)-9H-carbazole (epoxide) (compound of formula-II) with 2-(2-methoxyphenoxy) ethylamine (compound of formula-III) at a ratio of 1:1.15 to 1:1.45, at temperature 30° C. to 90° C. in a suitable organic solvent; b) preparing the salt of Carvedilol with suitable organic acid in a solvent; c) isolating the product as a salt with organic acid from an organic solvent; d) purifying the salt from organic solvent; e) treating said salt with a base to get free Carvedilol; and, f) purifying Carvedilol from organic solvent.