Patent ID: 8518677

Claim:
A method for the production of a cis- or trans-stilbenoid of the general formula 1: in which each or R 1 R 2 , R 3 , R 4 and R 5 independently is hydrogen or hydroxyl, or a glycosylated or oligomeric form thereof, comprising cultivating a micro-organism producing said stilbenoid, wherein said cultivation is performed in a multi-phase system comprising an aqueous first phase containing said micro-organism and a second phase immiscible with said aqueous phase in which said stilbenoid accumulates, wherein said second phase comprises an ester, and said ester is of the general formula R 6 —COO—R 7 , and R 6 is H or an aliphatic straight or branched chain hydrocarbon moiety of from 1-6 carbon atoms and R 7 is an aliphatic straight or branched chain hydrocarbon moiety of from 2-16 carbon atoms, or a heteroatom containing hydrocarbon moiety of from 2to 16 carbon atoms or an aromatic or heteroaromatic moiety of from 5 to 16 carbon atoms.