Patent ID: 7696223

Claim:
A compound of formula I: wherein: q is 0 or 1; A and B are independently selected from the group consisting ═C(R 7 )—, —N(R 8 )—, ═N—, and —S— with the proviso that at least one of the following is present: A is ═C(R 7 )— and B is —N(R 8 )—; A is —S— and B is ═N—; A ═N— and B is —S—; or A is —N(R 8 )— and B is ═C(R 7 )—; one of -A C(R 6 )— or —B C(R 6 )— is a double bond and the other is a single bond; R 1 is selected from the group consisting of hydroxyl, alkoxy, substituted alkoxy, acyloxy, cycloalkoxy, substituted cycloalkoxy, aryloxy, substituted aryloxy, heteroaryloxy, substituted heteroaryloxy, heterocyclyloxy, substituted heterocyclyloxy, mercapto, thioether, substituted alkylthio, arylsulfanyl, heteroarylsulfanyl, amino, substituted amino, acylamino, and aminoacyl; R 2 is selected from the group consisting of hydrogen, deuterium, and methyl; R 3 is selected from the group consisting of hydrogen, deuterium, alkyl, and substituted alkyl; R 4 is selected from the group consisting of hydrogen, alkyl, and substituted alkyl; R 5 is selected from the group consisting of hydrogen, halo, cyano, hydroxyl, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, cycloalkoxy, substituted cycloalkoxy, aryl, substituted aryl, aryloxy, substituted aryloxy, heteroaryl, substituted heteroaryl, heterocyclyl, substituted heterocyclyl, heterocyclyloxy, substituted heterocyclyloxy, heteroaryloxy, substituted heteroaryloxy, acyl, aminoacyl, nitro, amino, substituted amino, acylamino, sulfanyl, sulfonyl, thioether, arylthio, and substituted arylthio; R 6 and R 7 are each independently selected from the group consisting of hydrogen, halo, cyano, hydroxyl, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, cycloalkoxy, substituted cycloalkoxy, aryl, substituted aryl, aryloxy, substituted aryloxy, heteroaryl, substituted heteroaryl, heterocyclyl, substituted heterocyclyl, heterocyclyloxy, substituted heterocyclyloxy, heteroaryloxy, substituted heteroaryloxy, acyl, aminoacyl, nitro, amino, substituted amino, acylamino, sulfanyl, sulfonyl, thioether, arylthio, and substituted arylthio; or where when A or B is ═C(R 7 )—, then R 6 and R 7 together with the carbon atoms bound thereto join to form a cycloalkenyl, substituted cycloalkenyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl; and R 8 is selected from the group consisting of hydrogen, hydroxyl, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl; or a pharmaceutically acceptable salt, single stereoisomer, mixture of stereoisomers, or ester thereof.