Patent ID: 7550480

Claim:
A compound of the formula: wherein R 1 is an optionally substituted aryl or an optionally substituted heteroaryl ring; X is R 2 , OR 2 , S(O) m R 2 , (CH 2 ) n N(R 10 )S(O) m R 2 , (CH 2 ) n N(R 10 )C(O)R 2 , (CH 2 ) n NR 4 R 14 , NR 2 (CH 2 ) n NR 4 R 14 , O(CH 2 ) n NR 4 R 14 , S(CH 2 ) n NR 4 R 14 , (CH 2 ) n J, NR 2 (CH 2 ) n J, O(CH 2 ) n J, S(CH 2 ) n J, or (CH 2 ) n N(R 2 ) 2 ; J is an optionally substituted heteroaryl ring; n is 0 or an integer having a value of 1 to 10; m is 0 or an integer having a value of 1 or 2; q is 0 or an integer having a value of 1 to 10; R 2 is independently selected from a hydrogen, C 1-10 alkyl, aryl, arylC 1-10 alkyl, heteroaryl, or heteroarylC 1-10 alkyl moiety, which moieties, excluding hydrogen, are all optionally substituted; or R 2 is the moiety X 1 (CR 10 R 20 ) q C(A 1 )(A 2 )(A 3 ), or C(A 1 )(A 2 )(A 3 ); X 1 is N(R 10 ), O, S(O) m , or CR 10 R 20 ; X 2 is independently hydrogen, halogen or C 1-4 alkyl; A 1 is an optionally substituted C 1-10 alkyl; A 2 is an optionally substituted C 1-10 alkyl; A 3 is hydrogen or is an optionally substituted C 1-10 alkyl; G 1 is C—X 2 ; R 3 is C 1-10 alkyl, C 3-7 cycloalkyl, C 3-7 cycloalkylC 1-4 alkyl, aryl, arylC 1-10 alkyl, heteroaryl, heteroarylC 1-10 alkyl, heterocyclic, or a heterocyclylC 1-10 alkyl moiety, which moieties are optionally substituted; R 4 and R 14 are each independently selected from hydrogen, optionally substituted C 1-4 alkyl, optionally substituted aryl, or optionally substituted aryl-C 1-4 alkyl, arylC 1-10 alkyl, heteroaryl or heteroarylC 1-10 alkyl, wherein each of these moieties may be optionally substituted; R 10 and R 20 are independently selected from hydrogen or C 1-4 alkyl; or a pharmaceutically acceptable salt thereof.