Patent ID: 8759009

Claim:
A humanized anti-α2 integrin antibody comprising: (i) a heavy chain variable region comprising: a heavy chain complementarity determining region 1 (HCDR1) having the amino acid sequence GFSLTNYGIH (SEQ ID NO: 1), a heavy chain complementarity determining region 2 (HCDR2) having the amino acid sequence VIWARGFTNYNSALMS (SEQ ID NO: 2), and a heavy chain complementarity determining region 3 (HCDR3) having the amino acid sequence ANDGVYYAMDY (SEQ ID NO: 3); and (ii) a light chain variable region comprising: a light chain complementarity determining region 1 (LCDR1) having the amino acid sequence SAQSSVNYIH (SEQ ID NO:112), a light chain complementarity determining region 2 (LCDR2) having the amino acid sequence DTSKLAS (SEQ ID NO: 5), and a light chain complementarity determining region 3 (LCDR3) having the amino acid sequence QQWTTNPLT (SEQ ID NO: 6).