Patent ID: 7914991

Claim:
A method for detecting the presence or absence of nucleic acid having specific sequences in a sample comprising the step of: a) contacting a sample containing nucleic acids with nucleolipids comprising a lipophilic moiety and oligo- or poly-nucleotide moiety, whereby the oliqo- or poly- nucleotide moiety comprises a sequence which is substantially complementary to a specific sequence of a nucleic acid present in the sample and which hybridizes under hybridizing conditions with the nucleic acid having a specific sequence and the nucleic add present in the sample under hybridizing conditions; b) detecting the formation of hybridization products of nucleolipids and a specific sequence of a nucleic acid present in the sample, wherein the nucleolipids includes a nucleolipid compound comprising a lipophilic moiety (F) and a nucleoside, oligo- or polynucleotide moiety being connected with each other via a linker (L) and a spacer (S), wherein the linker is an amine group or a molecule having at least two functional groups, being connected with lipophilic moiety, and the nucleoside, oligo- or polynucleotide-moiety is linked via the functional moiety of a phosphoric acid diester.