Patent ID: 8227455

Claim:
A method of treating a cell proliferative disorder, comprising: administering to a subject in need thereof an amount of a prodrug, or a salt thereof, of a Syk kinase inhibitory compound effective to treat the cell proliferative disorder, the prodrug having the structure wherein each R 30 , R 31 and R 32 is independently selected from hydrogen, lower alkyl, lower alkenyl, lower alkynyl, (C6-C14) aryl, phenyl, 5-14 membered heteroaryl, (C7-C20) arylalkyl, benzyl, 7-20 membered heteroarylalkyl, —OR, chloro, fluoro, bromo, cyano, nitro, —C(O)R, —C(O)OR, —NRR, —S(O) 2 NRR, —C(O)NRR, —N(R)S(O) 2 R and —NC(O)OR, where each R is independently selected from hydrogen and lower alkyl; and R P is selected from —CH 2 —O—P(O)(OH) 2 , —CH 2 CH 2 —O—P(O)(OH) 2 , —CH 2 OH.