Patent ID: 8614064

Claim:
A method for identifying a subject at risk of developing atherosclerosis-associated plaque rupture or myocardial infarction comprising: a) obtaining a blood, serum, or plasma sample from the subject; b) measuring the level of Apolipoprotein A-I:Apolipoprotein A-II lipoprotein particles (Lp-A-I:II) containing Apolipoprotein C-1 (ApoCI) in the sample, thereby measuring the level of ApoCI-enriched HDL in the sample; c) comparing the level of ApoCI-enriched HDL in the sample to the level of ApoCI-enriched HDL from a control; and d) identifying the subject as at risk of developing atherosclerosis-associated plaque rupture or myocardial infarction when the ApoCI-enriched HDL level is increased in the sample as compared to the control.