Patent ID: 7465740

Claim:
A compound having the structural formula or a pharmaceutically acceptable salt thereof, wherein R is R 1 -isoxazolyl, R 1 -oxadiazolyl, R 1 -dihydrofuranyl, R 1 -pyrazolyl, R 1 -imidazolyl, R 1 -pyrazinyl or R 1 -pyrimidinyl; R 1 is 1, 2 or 3 substituents independently selected from the group consisting of H, alkyl, alkoxy and halo; Z is R 2 -aryl or R 2 -heteroaryl; R 2 is 1 to 5 substituents independently selected from the group consisting of hydrogen, alkyl, hydroxyalkyl, -alkylene-O—C(O)alkyl, alkoxyalkyl, (hydroxy)haloalkyl, (cycloalkyl)hydroxyalkyl, hydroxycycloalkyl, (halo)alkoxyalkyl, —C(O)alkyl, hydroxyalkoxy, alkoxyalkoxy, oxetanyloxy, halo, cyanoalkyl, haloalkyl, dialkylamino, R 3 -heteroaryl and R 3 -heteroarylalkyl; and R 3 is 1 to 3 substituents independently selected from the group consisting of H, alkyl, alkoxyalkyl, hydroxyalkyl, dialkylamino and cycloalkylaminocarbonyl.