Patent ID: 8569284

Claim:
A method for treating an influenza A virus-affected disease state or infection comprising the step of administering to a subject in need thereof a composition comprising a compound of formula (I): wherein (a) X and Y are independently a bond or alkylene; R 1 is alkyl, hydroxyl, carbonyl, carboxyl, cyano, amino, —CH(R 5 )(R 6 ), or forms an oxo group together with R 2 ; R 2 is alkyl, hydroxyl, carbonyl, carboxyl, cyano, amino, or —CH(R 5 )(R 6 ); R 3 and R 4 are independently hydrogen or —CH(R 7 )(R 8 ); R 5 and R 6 are independently hydrogen, alkyl, hydroxyl, carbonyl, or amino; R 7 and R 8 are independently hydrogen, alkyl, alkoxy, hydroxyl, carbonyl, or amino; dashed lines a and b are optional bonds; and, n is 0-3, or, (b) X and Y are independently a bond or alkylene; R 1 is hydrogen, alkyl, hydroxyl, carbonyl, carboxyl, cyano, —CH(R 5 )(R 6 ), or forms an oxo group together with R 2 ; R 2 is hydrogen, alkyl, hydroxyl, carbonyl, carboxyl, cyano, or —CH(R 5 )(R 6 ); R 3 and R 4 are independently hydrogen or —CH(R 7 )(R 8 ); R 5 and R 6 are independently hydrogen, alkyl, hydroxyl, or carbonyl; R 7 and R 8 are independently hydrogen, alkyl, alkoxy, hydroxyl, or carbonyl; dashed lines a and b are optional bonds; and, n is 0-3, or, (c) X and Y are independently a bond or alkylene; R 1 is amino, —CH(R 5 )(R 6 ), or forms an oxo group together with R 2 ; R 2 is hydrogen, alkyl, hydroxyl, carbonyl, carboxyl, cyano, amino, or —CH(R 5 )(R 6 ); R 3 is hydrogen or —CH(R 7 )(R 8 ); R 4 is —CH(R 7 )(R 8 ); R 5 and R 6 are independently hydrogen, alkyl, hydroxyl, carbonyl, or amino; R 7 and R 8 are independently hydrogen, alkyl, alkoxy, hydroxyl, carbonyl, or amino; dashed lines a and b are optional bonds; and, n is 0-3, or, (d) X and Y are independently a bond or alkylene; R 1 is hydrogen, alkyl, hydroxyl, carbonyl, carboxyl, cyano, amino, —CH(R 5 )(R 6 ), or forms an oxo group together with R 2 ; R 2 is hydrogen, alkyl, hydroxyl, carbonyl, carboxyl, cyano, amino, or —CH(R 5 )(R 6 ); R 3 and R 4 are independently hydrogen or —CH(R 7 )(R 8 ); R 5 and R 6 are independently hydrogen, alkyl, hydroxyl, carbonyl, or amino; R 7 and R 8 are independently hydrogen, alkyl, alkoxy, hydroxyl, carbonyl, or amino; at least one of lines a and b represents a bond; and, n is 0-3, or, or a stereoisomer, partial stereoisomer, prodrug, pharmaceutically acceptable salt, hydrate, solvate, acid hydrate, or N-oxide thereof.