Patent ID: 8383815

Claim:
A method for preparing a compound of Formula II from a compound of Formula I: the method comprising contacting the compound of Formula I with an acid and a non-supported, heterogeneous ruthenium metal catalyst in a reaction mixture to convert the compound of Formula I to the compound of Formula II, wherein: R 1 is chosen from hydrogen and substituted or unsubstituted alkyl, substituted or unsubstituted allyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aryl alkyl, substituted or unsubstituted aryl sulfonyl, substituted or unsubstituted alkyl sulfonyl, substituted or unsubstituted acyl, substituted or unsubstituted formyl, hydroxyl, substituted or unsubstituted carboxyester and substituted or unsubstituted carboxyamide; R 2 is chosen from hydrogen and substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aryl alkyl, substituted or unsubstituted acyl, substituted or unsubstituted aryl sulfonyl, substituted or unsubstituted alkyl sulfonyl, substituted or unsubstituted carboxyester, substituted or unsubstituted carboxyamide, substituted or unsubstituted trialkylsilyl, and substituted or unsubstituted heterocycloalkyl; R 8 and R 9 are independently chosen from hydrogen, hydroxyl, substituted or unsubstituted hydrocarbyl, or R 8 and R 9 together form a carbonyl group; R 10 , R 11 , R 14 and R 15 are independently chosen from hydrogen, substituted or unsubstituted hydrocarbyl, and a halogen, or R 14 and R 15 together form a carbonyl group; and, R 16 and R 17 are independently chosen from hydrogen, substituted or unsubstituted hydrocarbyl, or R 16 and R 17 together form a carbonyl group.