Patent ID: 8143428

Claim:
A compound according to Formula I: wherein: each Q is independently O, or S; each R 1 is independently selected from the group consisting of halogen, —(C 1 -C 8 )hydrocarbyl, —(═O)R y , —NR w 2 , —N(R w )C(═O)R y , —N(R w )CH(R z )C(═O)R y , —N(R w )SO 2 R y , —N(R w )(C 1 -C 4 )alkylene-CO 2 R w , —NO 2 , —CN, —OR w , —OC(═O)R y , —OCH(R z )C(═O)R y , —OSO 2 R y , —O(C 1 -C 4 )alkylene-CO 2 R w , —OP(═O)(OR w ) 2 , —O(C 2 -C 6 )alkylene-N(CH 3 ) 2 , —O(C 1 -C 6 )haloalkyl, —P(═O)(OR w ) 2 , —NHC(═NH)NHR x , —(C 1 -C 6 )haloalkyl and heteroalkyl; wherein two hydrocarbyl R 1 groups on adjacent carbon atoms of the phenyl ring of I may combine to form a phenyl ring fused to the compound of Formula I at the 5-6, the 6-7, or the 7-8 bond; R w is —(C 1 -C 8 )hydrocarbyl; R x is —H, —(C 1 -C 8 )hydrocarbyl or —C(═O)(C 1 -C 8 )hydrocarbyl; R y is selected from the group consisting of —H, —(C 1 -C 8 )hydrocarbyl, —O(C 1 -C 8 )hydrocarbyl, substituted phenyl, substituted heterocyclyl(C 1 -C 3 )alkyl, heteroaryl(C 1 -C 3 )alkyl, —(C 2 -C 10 )heteroalkyl, —(C 1 -C 6 )haloalkyl, —CH(R z )NHR x , —N(R w )R x , —(C 1 -C 3 )alkyleneNH 2 , —(C 1 -C 3 )alkyleneN(CH 3 ) 2 , —(C 1 -C 3 )perfluoroalkyleneN(CH 3 ) 2 , —(C 1 -C 3 )alkyleneN + ((C 1 -C 3 )alkyl) 3 , —(C 1 -C 3 )alkylene-N + (CH 2 CH 2 OH) 3 , —(C 1 -C 3 )alkylene-OR x , —(C 1 -C 4 )alkylene-CO 2 R x , —(C 1 -C 4 )alkylene-CO 2 N(R w )R x , —(C 1 -C 4 )alkylene-C(═O)halogen, halo(C 1 -C 3 )alkyl and —(C 1 -C 4 )perfluoroalkylene-CO 2 R x ; R z is selected from the group consisting of —H, —(C 1 -C 6 )alkyl, —(CH 2 ) 3 —NH—C(NH 2 )(═NH), —CH 2 C(═O)NH 2 , —CH 2 COOH, —CH 2 SH, —(CH 2 ) 2 C(═O)—NH 2 , —(CH 2 ) 2 CO 2 H, —CH 2 -(2-imidazolyl), —(CH 2 ) 4 —NH 2 , —(CH 2 ) 2 —S—CH 3 , phenyl, —CH 2 -phenyl, —CH 2 —OH, —CH(OH)—CH 3 , —CH 2 -(3-indolyl) and —CH 2 -(4-hydroxyphenyl); each n is independently selected from the group consisting of 1, 2, 3 and 4; M is selected from the group consisting of (a), (b), (c), (d) and (e): R 2 is substituted or unsubstituted aryl; R 3 and R 4 are independently selected from the group consisting of —H and —(C 1 -C 6 )alkyl; A is —SO 2 — or —C(═O)—; and m is 1; provided that: (i) when Q is O and M is: then R 1 is other than —NO 2 ; or a salt thereof.