Patent ID: 7498323

Claim:
A spiro-piperidine compound represented by formula (I): wherein R 1 represents hydrogen, an aliphatic hydrocarbon group which may have a substituent(s) or a cyclic group which may have a substituent(s); and ring A represents a tetrahydropyrimidin-2-(1H)-one group represented by the following formula which may have a substituent(s), in which 2,5-diketopiperazine having a spiro bond at the 3-position is excluded, wherein R 2 represents hydrogen, an aliphatic hydrocarbon group which may have a substituent(s) in which the aliphatic hydrocarbon group is selected from the group consisting of ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl, tert-butyl, pentyl, hexyl, heptyl, octyl, C2-8 alkenyl and C2-8 alkynyl, a hydroxyl group which may be protected, carboxy which may be protected, carbamoyl which may be protected, or a cyclic group which may have a substituent(s) and, R 5 represents hydrogen, an aliphatic hydrocarbon group which may have a substituent(s), hydroxyl which may be protected, carboxy which may be protected, or a cyclic group which may have a substituent(s), a salt thereof or a quaternary ammonium salt thereof, wherein the cyclic group of R 1 , R 2 and R 5 is selected from the group consisting of cyclopropane, benzene, cyclohexane, cyclohexene, thiophene, pyrazole, isothiazole, thiazole, imidazole, furan, dihydropyrazole, quinoline, benzodioxane, dioxaindane, benzofuran, pyridine, tetrahydropyran, triazole, pyrrole, oxazole, isoxazole, and oxadiazole.