Patent ID: 8470836

Claim:
A compound represented by Formula 1: wherein A is selected from a substituent of Formula 2: wherein R 1 is hydrogen or CF 3 , and R 2 is selected from the group consisting of hydrogen, substituted or unsubstituted C 1 -C 10 alkyl, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 heterocycloalkyl, substituted or unsubstituted C 4 -C 8 aryl and substituted or unsubstituted C 3 -C 7 heteroaryl; and a substituent of Formula 3: wherein R 3 is selected from the group consisting of hydrogen, halogen, and substituted or unsubstituted C 1 -C 4 alkyl; and B is selected from the group consisting of a substituent of Formula 4: wherein X is —CR 4 R 5 — or —CO—, wherein R 4 and R 5 are each independently hydrogen or hydroxy, provided that at least one of R 4 and R 5 is hydroxy, R 6 , R 7 , R 8 and R 9 are each independently selected from the group consisting of hydrogen, halogen and substituted or unsubstituted C 1 -C 4 alkyl, and n is 0 or 1; a substituent of Formula 5: wherein X is —CR 10 R 11 — or —CO—, wherein R 10 and R 11 are each independently hydrogen or hydroxy, provided that at least one of R 10 and R 11 is hydroxy, R 12 , R 13 and R 14 are each independently selected from the group consisting of hydrogen, halogen and substituted or unsubstituted C 1 -C 4 alkyl, and Y is oxygen or sulfur; a substituent of Formula 6: wherein X is —CR 15 R 16 — or —CO—, wherein R 15 and R 16 are each independently hydrogen or hydroxy, provided that at least one of R 15 and R 16 is hydroxy, Z is —CH— or oxygen, provided that when Z is oxygen, R 19 is absent, and R 17 , R 18 and R 19 are each independently selected from the group consisting of hydrogen, halogen, and substituted or unsubstituted C 1 -C 4 alkyl; and a substituent of Formula 7: wherein X is —CR 20 R 21 — or —CO—, wherein R 20 and R 21 are each independently hydrogen or hydroxy, provided that at least one of R 20 and R 21 is hydroxy, and R 22 is substituted or unsubstituted C 1 -C 4 alkyl; or a pharmaceutically acceptable salt thereof.