Patent ID: 7608739

Claim:
The compound of the Formula III; wherein: R 1 is selected from: H, F and OH; R 3 is selected from: H, (C 1 -C 6 )alkyl, (C 3 -C 6 )cycloalkyl, (C 2 -C 6 )alkenyl and (C 1 -C 6 )alkyl hydroxyl; R 4 is selected from: H, oxo, OH, halo, CN, NH 2 , NO 2 , (C═O) a O b (C 1 -C 10 )alkyl, (C═O) a O b (C 2 -C 10 )alkenyl, (C═O) a O b (C 2 -C 10 )alkynyl, (C═O) a O b (C 3 -C 6 )cycloalkyl, (C═O) a O b (C 0 -C 6 )alkylene-aryl, (C═O) a O b (C 0 -C 6 )alkylene-heterocyclyl, (C═O) a O b (C 0 -C 6 )alkylene-N(R b ) 2 , C(O)H, (C 0 -C 6 )alkylene-CO 2 H, C(O)N(R b ) 2 , and S(O) 2 N(R b ) 2 ; said alkyl, alkenyl, alkynyl, cycloalkyl, aryl, alkylene and heterocyclyl is optionally substituted with up to three substituents selected from R b ; R 5 is H or CH 3 ; R a is selected from: (C 1 -C 6 )alkyl, (C 3 -C 6 )cycloalkyl, aryl and heterocyclyl; said alkyl, cycloalkyl, aryl and heterocyclyl is optionally substituted with one or more substituents selected from OH,(C 1 - 6 )alkyl, (C 1 -C 6 )alkoxy, halogen, CO 2 H, CN, (O)C═O(C 1 -C 6 )alkyl, oxo and N(R c ) 2 ; R b is independently selected from: H, oxo, OH, halogen, CO 2 H, CN, (O)C═O(C 1 -C 6 )alkyl, N(R c ) 2 , (C 1 -C 6 )alkyl, aryl, heterocyclyl, (C 3 -C 6 )cycloalkyl, (C═O)O(C 1 -C 6 )alkyl, C═O(C 1 -C 6 )alkyl and S(O) 2 R a ; said alkyl, cycloalkyl, aryl or heterocylyl is optionally substituted with one or more substituents selected from OH, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, halogen, CO 2 H, CN, (O)C═O(C 1 -C 6 )alkyl, oxo, N(R c ) 2 and optionally substituted heterocyclyl, wherein said heterocyclyl is optionally substituted with (C 1 -C 6 )alkyl, oxo or NH 2 ; R c is independently selected from: H and (C 1 -C 6 )alkyl; a is 0 or 1; b is 0 or 1; p is 1 or 2; q is 0 or 1; or a pharmaceutically acceptable salt or stereoisomer thereof.