Patent ID: 8629282

Claim:
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: W is CH 2 or O; Q is R 1 is: (i) C 3-6 alkyl; (ii) C 3-7 cycloalkyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; (iii) phenyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; or (iv) pyridinyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; R 2 is C 1-6 alkyl, C 1-3 fluoroalkyl, C 3-7 cycloalkyl, or phenyl substituted with zero to 3 substituents independently selected from halo, —CN, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, and/or C 1-2 fluoroalkoxy; n is zero, 1, or 2; each R 3 is independently C 1-3 alkyl, F, Cl, C 1-3 fluoroalkyl, C 1-3 chloroalkyl, —CN, C 1-3 alkoxy, and/or C 1-3 fluoroalkoxy; R 4 is H or —CH 3 ; G is: (i) —NR a R a ; (ii) —NH(CR d R d ) 1-3 C(O)OR a , —NH(CR d R d ) 1-4 OH, —NHR e , or NR e R e ; (iii) —NH(CR d R d ) 1-3 CR b R c C(O)OR a , wherein R b and R c together with the carbon atom to which they are attached form a C 3-6 spirocycloalkyl ring; (iv) —NR a [(CR a R a ) 0-3 (C 3-6 cycloalkyl)], wherein said C 3-6 cycloalkyl is substituted with zero to 2 substituents independently selected from —(CR d R d ) 1-3 C(O)OR a and/or —(CR d R d ) 1-4 OH; (v) 5- to 6-membered heterocyclyl having at least one nitrogen heteroatom, wherein said heterocyclyl is substituted with zero to 2 substituents independently selected from —(CR d R d ) 0-3 C(O)OR a and/or —(CR d R d ) 0-4 OH; or (vi) —NR a C(O)OR a ; each R a is independently H, C 1-4 alkyl, and/or C 1-3 hydroxyalkyl; each R d is independently H, —OH, F, and/or —CH 3 ; and each R e is independently —(CR a R a ) 1-3 C(O)OR a .