Patent ID: 8759379

Claim:
A compound of Formula I, or a pharmaceutically acceptable salt, wherein, X 1 is selected from the group consisting of —C(O)—O—, —S(O)—, and —S(O 2 )—; X 2 is selected from the group consisting of —O—, —NR 6 —C(O)—NR 6 —, —OC(O)NR 6 —, —NR 6 —, and —NR 6 C(O)O—; L is selected from the group consisting of a covalent bond, alkylene, and —CHR 7 —; R 1 is selected from the group consisting of aryl, heteroaryl, arylalkyl, and heteroarylalkyl; each R 2 is independently selected from the group consisting of H, alkyl, arylalkyl, heterocyclylalkyl, and cycloalkylalkyl wherein at least one R 2 is arylalkyl; R 3 is selected from the group consisting of heterocyclyl, aryl, heteroaryl, arylalkyl, and heteroarylalkyl; R 4 and R 5 are each independently selected from the group consisting of H, alkyl, cycloalkyl, heterocyclyl, cycloalkylalkyl, arylalkyl, and heterocyclylalkyl; each R 6 is independently selected from the group consisting of H, alkyl, and cycloalkyl; and R 7 is selected from the group consisting of H, alkyl, substituted alkyl, and heterocyclylalkyl; wherein each aryl, heteroaryl, cycloalkyl, heterocyclyl, cycloalkylalkyl, heterocyclylalkyl, arylalkyl, and heteroarylalkyl of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 is unsubstituted or substituted.