Patent ID: 7485627

Claim:
A method for ameliorating gastrointestinal inflammation in a subject comprising: administering to a subject suffering from gastrointestinal inflammation a formulation comprising an immunomodulatory nucleic acid to the subject, wherein said immunomodulatory nucleic acid is isolated or synthetic, wherein the immunomodulatory nucleic acid comprises a nucleotide sequence selected from: a) Purine-Purine-[C]-[G]-Pyrimidine-Pyrimidine-3′; b) 5′-Purine-TCG-Pyrimidine-Pyrimidine-3′; c) 5′-[TCG] n -3′, where n is any integer that is 1 or greater; d) 5′-Purine-Purine-CG-Pyrimidine-Pyrimidine-CG-3′; and e) 5′-Purine-TCG-Pyrimidine-Pyrimidine-CG-3′, said administering being in an amount effective to ameliorate a symptom of gastrointestinal inflammation in the subject; wherein gastrointestinal inflammation is ameliorated in the subject.