Patent ID: 8318747

Claim:
A compound of formula Ia, or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof: wherein: X is S, SO, or SO 2 ; Y is NR 5 ; Z is ═O, CO 2 R 6 , or C 1-6 alkyl optionally substituted by aryl, hydroxy, carboxy, alkoxy, carbamoyl, or halo; R 1 and R 2 are each independently halogen, C 1-6 alkyl, or C 1-6 haloalkyl; R 3 is CN or NO 2 ; R 4 is hydrogen or C 1-6 alkyl optionally substituted by aryl, hydroxy, carboxy, alkoxy, carbamoyl, or halo; R 5 is hydrogen or C 1-6 alkyl; and R 6 is hydrogen or C 1-6 alkyl.