Patent ID: 7727999

Claim:
A compound of formula I, salts and stereoisomers thereof: wherein X is N(R N ); wherein R N is selected from hydrogen and C 1-6 alkyl; Y is selected from the group consisting of O and S; Z is CH; R 1 is hydrogen, or an optionally substituted substituent selected from the group consisting of C 1-6 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 3-8 cycloalkyl, aryl, heteroaryl, aryl(C 1-6 alkyl), heteroaryl(C 1-6 alkyl), heterocyclyl(C 1-6 alkyl), hydroxy(C 1-6 alkyl), amino(C 1-6 alkyl), and halo(C 1-6 alkyl); m is 0 and R 4 is absent; R 5 and R 6 are independently an optionally substituted substituent selected from the group consisting of aryl(C 1-6 alkyl), heteroaryl(C 1-6 alkyl), and heterocyclyl(C 1-6 alkyl), R 2 and R 3 are independently selected from the group consisting of hydrogen, halogen, hydroxy, and optionally substituted C 1-6 alkyl or selected such that R 2 and R 3 together form a ring system such that is selected from the group consisting of wherein R 7 and R 8 are independently selected from the group consisting of hydrogen, halogen, hydroxy, and C 1-6 alkyl.