Patent ID: 8658616

Claim:
A compound of formula I: wherein: Ar is naphthyl; T is selected from the group consisting of hydrogen (H—), fluoro (F—), methyl (—CH 3 ) and ethyl (—C 2 H 5 ); V is selected from the group consisting of hydrogen (—H), fluoro (—F) and OT′ where T′ is selected from the group consisting of hydrogen (—H), and methyl (—CH 3 ); T″ is hydrogen (—H); n is 0 or 1, wherein when n is 1, X is ═O, and when n is 0, a double bond exists between position 3 and position 4 and X is selected from the group consisting of H, OH, F, CI, Br, I, C 1-6 alkyl and NR 5 R 6 , where each of R 5 , and R 6 is independently selected from H and C 1-6 alkyl; Z is selected from the group consisting of H, F, and Cl; Y is selected from the group consisting of H, F, Cl, Br, NH 2 and NR 5 R 6 , where each of R 5 and R 6 is independently selected from H and C 1-6 -alkyl; Q is selected from the group consisting of O, and S; each of R 1 and R 2 is independently selected from the group consisting of H, C 1-20 alkyl, C 2-20 alkenyl, C 1-20 alkoxy, C 1-20 alkoxyC 1-20 alkyl, C 1-20 alkoxyC 6-30 aryl, C 2-20 alkynyl, C 3-20 cycloalkylC 6-30 aryl, C 6-30 aryloxy and C 5-20 heterocyclyl, any of which is optionally substituted with a substituent selected from the group consisting of electron donating and electron withdrawing moieties; each of R 3 and R 4 is independently selected from the group consisting of H, C 1-20 alkyl, C 2-20 alkenyl, C 1-20 alkoxy, C 1-20 alkoxyC 1-20 alkyl, C 1-20 alkoxyC 6-30 aryl, C 2-20 alkynyl, C 3-20 cycloalkylC 6-30 aryl, C 6-30 aryloxy and C 5-20 heterocyclyl, any of which is optionally substituted with a substituent selected from the group consisting of electron donating and electron withdrawing moieties; with the proviso that —R 1 and R 4 are together defined as a —(CH 2 ) 3 — alkylene chain; and pharmaceutically acceptable salts thereof.