Patent ID: 8211921

Claim:
A compound including resolved enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, said compound having the formula: where X is CR 10 ; R 10 is hydrogen, halogen, methyl, fluoromethyl, difluoromethyl, fluoromethyl or ethyl; R 9 is hydrogen, halogen, methyl, fluoromethyl, difluoromethyl, trifluoromethyl or ethyl; R 1 and R 2 are independently hydrogen, halogen, methyl, fluoromethyl, difluoromethyl, trifluoromethyl or ethyl; R 8 is halogen, hydroxyl, cyano, nitro, azido, methyl, fluoromethyl, difluoromethyl, trifluoromethyl, methoxy, fluoromethoxy, difluoromethoxy, trifluoromethoxy, amino, aminomethyl, dimethylamino, aminoethyl, diethylamino, ethyl, ethoxy or SR 11 ; R 7 is C 1 -C 4 alkyl, C 2 -C 4 alkenyl or C 2 -C 4 alkynyl, wherein said C 1 -C 4 alkyl, C 2 -C 4 alkenyl and C 2 -C 4 alkynyl may be optionally substituted with one or more groups selected from halogen, hydroxyl, cyano, nitro, azido, fluoromethyl, difluoromethyl, trifluoromethyl, methoxy, fluoromethoxy, difluoromethoxy, amino, aminomethyl, dimethylamino, aminoethyl, diethylamino, ethoxy, cycloalkyl, heterocycloalkyl, aryl or heteroaryl, wherein said cycloalkyl, heterocycloalkyl, aryl or heteroaryl rings may be optionally substituted with one or more groups selected from halogen, hydroxyl, cyano, nitro, azido, fluoromethyl, difluoromethyl, trifluoromethyl, C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 3 -C 6 cycloalkyl, C 3 -C 6 heterocycloalkyl, NR 3 R 4 and OR 3 ; R 4 and R 5 are independently hydrogen or C 1 -C 6 alkyl; R 11 is hydrogen, lower alkyl, lower alkenyl, aryl or arylalkyl; W is selected from C(O)OR 3 and C(O)NHOR 3 ; and R 3 is selected from hydrogen, C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 3 -C 6 cycloalkyl and C 3 -C 6 heterocycloalkyl, wherein any of said C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, cycloalkyl or heterocycloalkyl are optionally substituted with one or more groups selected from NR 3 R 4 and OR 3 .