Patent ID: 7772239

Claim:
A method of treating a disorder of reduced motility of the gastrointestinal tract in a mammal, the method comprising administering to the mammal a pharmaceutical composition comprising a pharmaceutically-acceptable carrier and a compound of formula (I): wherein: R 1 is hydrogen or C 1-3 alkyl; R 2 is hydrogen or C 1-3 alkyl; R 3 is C 1-3 alkyl; R 4 is —C(O)R 5 , —S(O) 2 R 6 , or R 3 and R 4 together with the nitrogen atom to which they are attached form R 5 is hydrogen, C 1-3 alkyl, —NH 2 , or pyridinyl, wherein C 1-3 alkyl is optionally substituted with hydroxy; R 6 is C 1-3 alkyl, —NH 2 , or imidazolyl, wherein imidazolyl is optionally substituted with C 1-3 alkyl; R 7 is —NR 9 S(O) 2 C 1-3 alkyl, —NR 10 C(O)R 11 , or R 8 is —S(O) 2 C 1-3 alkyl or —C(O)R 12 ; R 9 , R 10 , and R 11 are each independently C 1-3 alkyl; and R 12 is hydrogen, C 1-3 alkyl, or tetrahydrofuranyl; or a pharmaceutically-acceptable salt or stereoisomer thereof.