Patent ID: 8648070

Claim:
A compound of the formula 1, wherein R 1 is selected from the group consisting of phenyl and furanyl, optionally substituted by one or two residues selected from halogen or C 1-6 -alkyl, optionally substituted with one or more F atoms; X 1 is absent or methylene optionally substituted with C 1-5 -alkyl, said alkyl optionally substituted with one or more F atoms, C 1-4 -alkyl-O—, CN or C 3-8 -cycloalkyl, wherein optionally one carbon atom is replaced by an O; R 2 is H; R 3 is H, halogen, CN, C 1-6 -alkyl, optionally substituted with one or more F atoms; A is a N-linked 7-13 membered non-aromatic bicyclic system in which the two rings are either condensed to each other or joined in a spiro system and in which if present one CH group can be optionally replaced by N and one, two three or four CH 2 groups in said system are optionally replaced by NH, CO, O, S, SO, SO 2 , and one, two three or four positions on said ring system are optionally substituted with one or more F atoms, C 1-6 -alkyl, optionally substituted with one or more F atoms, C 1-6 -alkyl-OC(O)—, HO—C 1-6 -alkyl or C 1-6 -alkyl-O—C 1-6 -alkyl- and in which optionally two of these substituents are joined to form an additional ring or a pharmaceutically acceptable salt thereof.