Patent ID: 7144904

Claim:
A pharmaceutical composition comprising a compound represented by formula (I), in combination with a pharmaceutically acceptable excipient, wherein formula (I) is where: R is N(OH)R 8 ; R 1 is H, CH 3 or absent; R 2 is H, CH3 or absent, provided that R 1 and R 2 are not both absent; R 3 is H, CH 3 or R 3 is absent when one of R 1 or R 2 is absent forming a double bond between the R 1 /R 2 carbon and the R 3 carbon; R 4 is H, acyl of 1–4 carbons or alkyl of 1–4 carbons; R 5 is H, OH, O-acyl of 1–4 carbons, O-alkyl of 1–4 carbons, or (CH 2 ) a (R 10 ) b (CH 2 ) a R 10 (CH 2 ) a (R 10 ) b X; R 6 is H, OH, alkyl of 1–6 carbons, a halogen, (CH 2 ) a R 10 (CH 2 ) r R 10 Y, or is —C═C—C═C—, which, together with R 11 forms a fused ring system as follows: R 8 H is alkyl of one to four carbons, optionally substituted benzyl; R 9 is H, alkyl of one to four carbons or optionally substituted benzyl; R 10 is O or CH 2 ; R 11 is OH, O-acyl of 1–4 carbons, O-alkyl of 1–4 carbons or R 11 is part of a fused ring system when R 6 is —C═C—C═C—; A is CH or COH; B is S; a is 2 or 3; b is 0 or 1; m is an integer from 1 to 8; n is 0; p is 0; r is 2 or 3; X is Y is Z is wherein each of the substituents shown is defined above, or a compound of formula (I) where the ring containing the B and N moieties is fully reduced and contains no double bonds, or a pharmaceutically acceptable salt of the compound represented by formula (I) or a stereoisomer of the compound or mixture of stereoisomers.