Patent ID: 8415098

Claim:
A method for isolating a specific genomic region while maintaining interaction of the specific genomic region with its interacting molecule(s), the method comprising the steps 1 to 5: step 1: preparing a cell in which a DNA fragment having a recognition sequence(s) for an exogenous DNA-binding molecule is inserted in genomic DNA of a genomic region to be isolated; step 2: bringing genomic DNA of the cell into contact with an exogenous molecule at least having a DNA-binding domain of the exogenous DNA-binding molecule; step 3: performing a treatment for maintaining interaction of the genomic DNA of the cell with a molecule(s) interacting with the genomic DNA; step 4: performing a treatment for fragmenting the genomic DNA; and step 5: allowing a complex to be formed by binding of a molecule capable of specifically binding to the exogenous molecule, and then collecting the complex.