Patent ID: 7238784

Claim:
A reagent for use in a one-step hemagglutinin test to determine the presence of one or more Rh antigens on red blood cells, said reagent comprising: A) hybrid IgG anti-Rh antibody comprising: a) an IgG anti-Rh antibody that comprises two light chains and two heavy chains wherein said heavy chains each comprise an amino terminal end and a carboxy terminal end; and b) a polymeric tailpiece attached to the carboxy terminal end of each of said heavy chains, said polymeric tailpiece being selected from the group consisting of IgM tailpieces, IgA tailpieces, and peptides having a length of 30 amino acids or less, wherein said peptides comprise an accessible cysteine residue, which is capable of rendering the hybrid IgG anti-Rh antibody polymeric; and B) a carrier solution for said hybrid IgG anti-Rh antibody.