Patent ID: 7968720

Claim:
A compound of the formula (I) wherein the dotted line in the 6-membered nitrogen containing ring Z of formula (I) (said ring Z consisting of the numbered ring atoms 1 to 6) indicates that either a double bond is present at the 3,4- or at the 4,5-position of the ring Z of formula (I) or that no double bond is present in the ring Z of formula (I); and wherein a double bond can be present at the 3,4- or at the 4,5-position of the ring Z of formula (I); or or: no double bond may be present in the ring Z of formula (I) if: i) X represents N or N + —O − , or ii) V represents —O—CH 2 -Q-, or iii) W represents para-substituted phenyl or para-substituted pyridinyl, and V represents a pyrrolidinyl of the formula: X represents CH, N, or N + —O − ; W represents a para-substituted phenyl, a para-substituted pyridinyl, or a thiazolyl; V represents —O—CH 2 -Q-, wherein Q is bound to the group U of formula (I); or: V represents a pyrrolidinyl of the formula: U represents unsubstituted aryl; mono-, di-, tri- or tetra-substituted aryl, wherein the substituents are independently selected from C 1-7 -alkyl, —CF 3 , halogen and hydroxy-C 1-7 -alkyl; or five-membered heteroaryl containing two heteroatoms independently selected from nitrogen, oxygen and sulfur, wherein said heteroaryl radical is optionally mono-, di- or tri-substituted, wherein the substitutents are independently selected from C 1-7 -alkyl, C 1-7 -alkoxy, —CF 3 , —OCF 3 , and halogen; Q represents a five-membered heteroaryl with two or three heteroatoms independently selected from O and N; R 1 represents C 1-7 -alkyl or cycloalkyl; R 2 represents halogen or C 1-7 -alkyl; R 3 represents halogen, C 1-7 -alkyl, C 1-7 -alkoxy, —CF 3 , or hydrogen; R 4 represents C 1-7 -alkyl-O—(CH 2 ) 0-4 —CH 2 —; CF 3 —O—(CH 2 ) 0-4 —CH 2 —; R′R″N—(CH 2 ) 0-4 —CH 2 —, wherein R′ and R″ are independently selected from the group consisting of hydrogen, C 1-7 -alkyl (optionally substituted by one to three fluorine), cyclopropyl (optionally substituted by one to three fluorine), cyclopropyl-C 1-7 -alkyl (optionally substituted by one to three fluorine), and —C(═O)—R′″ wherein R′″ is C 1-4 -alkyl, C 1-4 -alkoxy, —CF 3 , —CH 2 —CF 3 , or cyclopropyl; or R 12 NH—C(═O)—(O)O—, —(CH 2 ) 0-4 —, wherein R 12 is C 1-4 -alkyl, C 1-4 -alkoxy, or cyclopropyl; n represents the integer 0; and salts thereof.