Patent ID: 8901140

Claim:
A compound of formula (I), or a tautomer, racemate, enantiomer, diastereoisomer or mixture thereof, or a pharmaceutically acceptable salt thereof: wherein: A is carbon atom, R 1 is selected from the group consisting of hydrogen and alkoxyl; wherein said alkoxyl is optionally substituted with one or more groups selected from the group consisting of halogen and alkoxyl; R 2 is cyano; R 3 is a radical having the following formula: wherein: D is selected from the group consisting of aryl and heteroaryl, wherein said aryl or heteroaryl is each independently optionally substituted with one or more groups selected from the group consisting of halogen, alkyl and trifluoromethyl; T is selected from the group consisting of —(CH 2 )r-, —O(CH 2 )r-, —NH(CH 2 )r- and —S(O)r(CH 2 )r-; and L is selected from the group consisting of aryl and heteroaryl, wherein said aryl or heteroaryl is each independently optionally substituted with one or more groups selected from the group consisting of halogen and alkyl; R 4 and R 5 are each independently selected from the group consisting of hydrogen, alkyl, alkoxyl, hydroxyl, hydroxyalkyl, halogen, carbonyl, amino, cyano, nitro, carboxyl and carboxylic ester; B is selected from the group consisting of carbon atom, oxygen atom and S(O)r; when B is carbon atom, R 6 and R 7 are each independently selected from the group consisting of hydrogen, alkyl, alkoxyl, hydroxyl, hydroxyalkyl, halogen, carbonyl, amino, cyano, nitro, carboxyl and carboxylic ester; when B is oxygen atom or S(O)r, R 6 and R 7 are absent; R 8 is selected from the group consisting of hydrogen and alkyl; R 9 is selected from the group consisting of hydrogen, alkyl, aryl, carboxyl and carboxylic ester; r is 0, 1, or 2; and n is 1, 2, 3, 4, or 5.