Patent ID: 7744908

Claim:
A pharmaceutical formulation, comprising a weakly basic pharmaceutically active ingredient, a liquid base, a clay selected from the group consisting of laponite, bentonite, montmorillonite, beidelite, hectorite, saponite and stevensite and mixtures thereof in an amount from about 0.25% (w/w) to about 0.5% (w/w), and at least one water soluble cellulose ether in an amount from about 0.8% (w/w) to about 2.0% (w/w), wherein the pharmaceutical formulation is orally ingestible and exhibits the following spill resistant characteristics: a) a viscosity within the range of about 5,000 to about 25,000 cps using a Brookfield viscometer at a spindle speed of 20 rpm; b) a viscometric yield value of a semi-solid; a spill-resistant consistency permitting the composition to be squeezed by light manual pressure through a channel of about 1-5 mm; c) the yield value allows the formulation to spread in a spoon bowl sufficiently quickly for accurate measurement, and to remain in the spoon bowl without spilling for several seconds on spoon inversion, tilting and vibration; d) homogeneity such that the components do not separate under conditions of use; and e) a storage stability such that the foregoing properties are retained for at least two months of storage at accelerated stability conditions of elevated temperature and humidity.