Patent ID: 8703188

Claim:
A method of treating cancer by radiosensitizing hypoxic tumor cells, the method comprising performing radiation treatment on a patient combined with the administration to the patient of at least one solid pharmaceutical composition dosage form comprising: i) nimorazole or a pharmaceutically acceptable salt thereof; ii) a disintegrant; iii) optionally one or more additional excipients; and iv) a coating sufficient to substantially mask the taste of said nimorazole; wherein said at least one solid pharmaceutical composition dosage form allows administration both by directly swallowing the unaltered dosage form and by allowing the dosage to disintegrate or disperse in an aqueous medium and to be administered to the patient via a feeding tube, and wherein one or more of said dosage forms are dispersible at a concentration of at least 1000 mg nimorazole in 100 ml water at 25° C. within 5 minutes upon stirring, thereby providing a dispersion that passes through a sieve screen with a nominal mesh aperture of 710 μm.