Patent ID: 7858654

Claim:
A compound of formula I: or pharmaceutically acceptable salts thereof, wherein: R 1 is imidazolyl optionally substituted once, twice or three times with C 1-6 alkyl, halo-C 1-6 alkyl, hetero-C 1-6 alkyl, C 1-6 alkoxy, heterocyclyl-C 1-6 alkyl, C 1-6 alkoxycarbonyl, C 1-6 alkylaminocarbonyl, di-C 1-6 alkylaminocarbonyl, phenyl, heterocyclyl, C 3-6 -cycloalkyl, C 3-6 cycloalkyl-C 1-6 alkyl or cyano; R 2 is: phenyl substituted at the 4-position with methyl or halo and optionally substituted at the 2- and 6-positions with halo; or pyridinyl substituted with methyl or halo at the 5-position and optionally substituted with halo at the 3-position; R 3 is: hydrogen; C 1-6 alkyl; hetero-C 1-6 alkyl; or cyano; R 4 is: hydrogen; C 1-6 alkyl; or hetero-C 1-6 alkyl; or R 3 and R 4 together with the atom to which they are attached may form a C 3-6 carbocyclic ring; R 5 is: hydroxymethyl, methoxymethyl, pyrazin-2-yl, 5-methyl-pyrazin-2-yl, 6-methyl-pyridazin-3-yl, or 1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl; or R 4 and R 5 together with the atom to which they are attached may form a C 3-6 carbocyclic ring that is optionally substituted with hydroxy; or R 4 and R 5 together with the atom to which they are attached may form a C 4-6 heterocyclic ring containing one or two heteroatoms each independently selected from 0, N and S; or R 3 , R 4 and R 5 together with the atom to which they are attached may form a six-membered heteroaryl containing one or two nitrogen atoms, and which is optionally substituted with halo, amino or C 1-6 alkyl; and R 6 , R 7 and R 8 each independently is: hydrogen C 1-6 alkyl; C 1-6 alkyloxy; halo; C 1-6 halo alkyl; or cyano.