Patent ID: 6849646

Claim:
A compound of formula I in which R 1 is CH 2 OR 10 , COOR 10 , CONHR 10 or CON(R 12 ) 2 , R 2 is R 10 , CO—R 10 , CO—R 6 , COOR 6 , COOR 10 , SO 2 R 6 , SO 2 R 10 , CONHR 6 , CON(R 6 ) 2 , CONHR 10 or CON(R 12 ) 2 , R 3 is H, Hal, NHR 10 , N(R 12 ) 2 , —NH-acyl, —O-acyl, CN, NO 2 , OR 10 , SR 10 , SO 2 R 10 , SO 3 R 10 , COOR 10 , CONHR 6 , CON(R 6 ) 2 , CONHR 10 or CON(R 12 ) 2 , R 4 is H, A, Ar or aralkylene having 7-14 C atoms, R 5 is NH 2 , H 2 N—C(═NH) or H 2 N—(C═NH)—NH, where the primary amino groups can also be provided with conventional amino protective groups, or can be mono- di- or trisubstituted by R 10 , CO—R 10 , COOR 10 or SO 2 R 10 , or R 6 —NH—, R 6 is a mono- or binuclear heterocycle having 1 to 4 N, O and/or S atoms, which can be unsubstituted or mono-, di- or trisubstituted by Hal, A, —CO-A, OH, CN, COOH, COOA, CONH 2 , NO 2 , ═NH or ═O, R 7 , R 8 in each case independently of one another is H or together form another bond on the ring such that a double bond is formed, Z is absent, O, S, NH, NR 1 , C(═O), CONH, NHCO, C(═S)NH, NHC(═S), C(═S), SO 2 NH, NHSO 2 or CA═CA′, R 9 is H, Hal, OR 11 , NH 2 , NHR 12 , N(R 12 ) 2 , NHAcyl, OAcyl, CN, NO 2 , SR 11 , SOR 12 , SO 2 R 12 or SO 3 H, R 10 is H, A, Ar or aralkylene having 7-14 C atoms, R 11 is H or alkyl with 1-6 C atoms, R 12 is alkyl having 1-6 C atoms, A is H or alkyl having 1-15 C atoms or cycloalkyl having 3-15 C atoms, which is unsubstituted or is mono-, di- or trisubstituted by R 9 and in which one, two or three methylene groups can also be replaced by N, O and/or S, Ar is a mono- or binuclear aromatic ring system having 0, 1, 2, 3 or 4 N, O and/or S atoms, which is unsubstituted or mono-, di- or trisubstituted by A and/or R 9 , Hal is F, Cl, Br or I, m, n in each case independently of one another are 0, 1, 2, 3 or 4, or a physiologically acceptable salt or solvate or enantiomer or diastereomer thereof.