Patent ID: 8865882

Claim:
A probe set for detecting biomarkers in a sample indicative of HPV-associated precancer and cancer, said probe set consisting of a probe that hybridizes to 3q26, a probe that hybridizes to 5p15, a probe that hybridizes to 20q13, and a probe that hybridizes to cen7, wherein: (a) the probe that hybridizes to 3q26 comprises a probe preparation of seven different nick-translated clones corresponding to chromosome 3, clones 1-7 of Table 4; (b) the probe that hybridizes to 5p15 comprises a probe preparation of five different nick-translated clones corresponding to chromosome 5, clones 1-5 of Table 4; (c) the probe that hybridizes to 20q13 comprises a probe preparation of three different nick-translated clones corresponding to chromosome 20, clones 1-3 of Table 4; and (d) the probe that hybridizes to cen7 comprises a probe preparation of a nick-translated clone corresponding to chromosome 7, clone 1 of Table 4.