Patent ID: 8269014

Claim:
A compound selected from: 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(TRANS-4-METHOXY-CYCLOHEXYL)-(TRANS-4-METHYL-CYCLOHEXANECARBONYL)-AMINO]-THIOPHENE-2-CARBOXYLIC ACID; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(TRANS-4-METHYL -CYCLOHEXANECARBONYL)-(CIS-4-[1,2,4]TRIAZOL-1-YL-CYCLOHEXYL) -AMINO]-THIOPHENE-2-CARBOXYLIC ACID; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(TRANS-4-METHYL -CYCLOHEXANECARBONYL)-(TRANS-4-[1,2,4]TRIAZOL-1-YL-CYCLOHEXYL)-AMINO]-THIOPHENE-2-CARBOXYLIC ACID; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(CIS-4-HYDROXY-CYCLOHEXYL)-(TRANS-4-METHYL-CYCLOHEXANECARBONYL)-AMINO]-THIOPHENE-2-CARBOXYLIC ACID; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(TRANS-4-METHYL -CYCLOHEXANECARBONYL)-(1-METHYL-PIPERIDIN-4-YL)-AMINO]-THIOPHENE-2-CARBOXYLIC ACID; HYDROCHLORIDE; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-](TRANS-4-METHYL -CYCLOHEXANECARBONYL)-(4-CIS-[1,2,3]TRIAZOL-1-YL-CYCLOHEXYL)-AMINO]-THIOPHENE-2-CARBOXYLIC ACID; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(TRANS-4-METHYL -CYCLOHEXANECARBONYL)-(TRANS-4-[1,2,3]TRIAZOL-1-YL-CYCLOHEXYL) -AMINO]-THIOPHENE-2-CARBOXYLIC ACID; 5-(3,3-DIMETHYL-BUT-1-YNYL)-3-[(TRANS-4-FLUORO-CYCLOHEXYL)-(TRANS-4-METHYL-CYCLOHEXANECARBONYL)-AMINO]-THIOPHENE-2-CARBOXYLIC ACID; and pharmaceutically acceptable salts thereof.