Patent ID: 8513273

Claim:
A compound of formula I-A1 wherein U is ═N— or ═C(R 5 )—; V is —CH═ or —N═; W is ═CH— or ═N—; with the proviso that no more than one of U, V or W is nitrogen; R 5 is hydrogen, methyl or halogen; R 1 is phenyl or heteroaryl, each of which is optionally substituted by one or two substituents, selected from halogen, lower alkyl and lower alkoxy; R 2 and R 2′ are each independently hydrogen, lower alkyl, hydroxy, lower alkoxy, C 3 -C 6 -cycloalkyl, or CH 2 -lower alkoxy, or together with the carbon atom to which they are attached form a C 3 -C 6 -cycloalkyl group or a ring containing —CH 2 OCH 2 —; and R 3 and R 3′ are each independently hydrogen, lower alkyl, or CH 2 -lower alkoxy or together with the carbon atom to which they are attached form a C 3 -C 6 -cycloalkyl group; or R 3 and R 2 together with the carbon atom to which they are attached form a C 3-6 -cycloalkyl group or a ring containing —(CH 2 ) 2 OCH 2 —; or a pharmaceutically acceptable acid addition salt, a racemic mixture, an enantiomer, an optical isomer and/or stereoisomer thereof.