Patent ID: 7723399

Claim:
Compounds of the formula Ia and IIa wherein A is unsubstituted ethylene or propylene, ethylene or propylene substituted by C 1 -C 18 alkyl, C 6 -C 14 aryl, aralkyl, C 5 -C 12 cycloalkyl, halogen, OH, C 1 -C 18 alkoxy, C 1 -C 18 alkylthio, carboxy, C 1 -C 18 alkoxycarbonyl, carbamoyl (C(O)NH 2 ), C 1 -C 18 alkylcarbamoyl, di-C 1 -C 18 alkylcarbamoyl, acyl, nitro, amino, C 1 -C 18 alkylamino or di-C 1 -C 18 alkylamino; or A is —CH 2 —X—CH 2 — wherein X is O, NH, N(C 1 -C 18 alkyl); or —N(OH)—CO—N(OH)—; or A together with the adjacent —CO—N—CO— group may form a bicyclic or polycyclic ring, said ring having up to 20 non hydrogen atoms, and wherein said ring may contain the structural element more than once; R 12 and R 13 independently of one another are hydrogen, C 1 -C 18 alkyl, cyclohexyl, phenyl, benzyl, or R 12 and R 13 form together with the N atom to which they are attached a 5 or 6 membered ring, optionally interrupted by —NH—, —N(C 1 -C 8 alkyl)-, —O— and/or S-atoms, A′ is unsubstituted ethylene or propylene, ethylene or propylene substituted by C 1 -C 18 alkyl, C 6 -C 14 aryl, aralkyl, C 5 -C 12 cycloalkyl, halogen, OH, C 1 -C 18 alkoxy, C 1 -C 18 alkylthio, carboxy, C 1 -C 18 alkoxycarbonyl, carbamoyl (C(O)NH 2 ), C 1 -C 18 alkylcarbamoyl, di-C 1 -C 18 alkylcarbamoyl, acyl, nitro, amino, C 1 -C 18 alkylamino or di-C 1 -C 18 alkylamino; or A′ is —CH 2 —X—CH 2 — wherein X is O, NH, N(C 1 -C 18 alkyl); or —N(OH)—CO—N(OH)—; or A′ together with the adjacent —CO—N—CO— group may form a bicyclic or polycyclic ring, said ring having up to 20 non hydrogen atoms, and wherein said ring may contain the structural element more than once; R 6 is hydrogen, C 1 -C 18 alkyl, cyclohexyl, phenyl, benzyl, NR 14 R 15 ; wherein R 14 and R 15 independently of one another are hydrogen, C 1 -C 18 alkyl, cyclohexyl, phenyl or R 14 and R 15 form together with the N atom to which they are attached a 5 or 6 membered ring, optionally interrupted by —NH—, —N(C 1 -C 8 alkyl)-, —O— and/or S-atoms, R 7 is hydrogen, C 1 -C 18 alkyl, cyclohexyl, phenyl, benzyl; or R 7 and R 14 or R 7 and R 15 form together with the N-atom attached to R 7 a 5-6 membered ring, optionally interrupted by —NH—, —N(C 1 -C 8 alkyl)-, —O— and/or S-atoms.