Patent ID: 7537767

Claim:
A composition comprising: (a) a virus-like particle; (b) at least one immunostimulatory substance; (i) wherein said immunostimulatory substance is an immunostimulatory nucleic acid; and (ii) wherein said immunostimulatory substance is packaged into said virus-like particle; and (c) at least one antigen or antigenic determinant; (i) wherein said antigen or antigenic determinant is bound to said virus-like particle; and (ii) wherein said antigen or antigenic determinant comprises a human melanoma MelanA peptide analogue that comprises an amino acid sequence derived from the amino acid sequence of SEQ ID NO:78 or SEQ ID NO:79 by alteration of one or two amino acid(s) or amino acid derivative(s) in said amino acid sequence, wherein said alteration comprises an amino acid substitution, deletion or insertion or a combination thereof.