Patent ID: 8524911

Claim:
A compound of formula (II), or a pharmaceutically acceptable salt thereof, wherein: R 1 , R 2 , R 9 , R 10 , R 11 , R 12 , R 13 and R 14 are independently selected from hydrogen, halogen, cyano, nitro, azido, —OR 3 , —NR 4 C(O)OR 6 , —OC(O)R 3 , —NR 4 S(O) j R 6 , —S(O) j NR 3 R 4 , —S(O) j NR 4 C(O)R 3 , —C(O)NR 4 S(O) j R 6 , S(O) j R 6 , —NR 4 C(O)R 3 , —C(O)NR 3 R 4 , —NR 5 C(O)NR 3 R 4 , —NR 5 C(NCN)NR 3 R 4 , —NR 3 R 4 , C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 10 cycloalkyl, C 3 -C 10 cycloalkylalkyl or —S(O) j (C 1 -C 6 alkyl); provided that R 12 is not OH, and R 13 , R 14 are not C 1 -C 10 alkyl; R 3 is selected from hydrogen, trifluoromethyl, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 10 cycloalkyl or C 3 -C 10 cycloalkylalkyl, where each alkyl, alkenyl, alkynyl and cycloalkyl is unsubstituted or substituted with primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro or trihalomethyl; R 4 is selected from hydrogen or C 1 -C 6 alkyl, whereby alkyl may be unsubstituted or substituted with primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro or trihalomethyl; R 5 is selected from hydrogen or C 1 -C 6 alkyl, whereby alkyl may be unsubstituted or substituted with primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro or trihalomethyl; R 6 is selected from trifluoromethyl, C 1 -C 10 alkyl or C 3 -C 10 cycloalkyl; W is selected from —C(O)OR 15 , —C(O)NR 4 R 15 , —C(O)NR 4 OR 15 , —C(O)NR 4 S(O) j R 6 , —C(O)NR 4 NR 4 R 15 , —NR′C(O)R′, —NR′S(O) j R′, —NRC(O)NR′R″, NR′S(O) j NR′R″ or —C(O)NR 4 NR 4 C(O)R 15 ; provided that W is not C(O)OH; R 15 is independently selected from hydrogen, trifluoromethyl, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 10 cycloalkyl, C 3 -C 10 cycloalkylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocyclyl or heterocyclylalkyl, where each alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl and heterocyclyl is unsubstituted or substituted with primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro, trihalomethyl, O—C 1 -C 4 alkyl or NR′R″; R′ and R″ are independently selected from hydrogen, C 1 -C 4 alkyl, C 2 -C 4 alkenyl, aryl or arylalkyl; X is N or N + O − ; and j is 1 or 2, with the proviso that 3-Phenylamino-isonicotinic acid methyl ester and 3-Oxo-3-(3-phenylamino-pyridin-4-yl)-propionic acid ethyl ester are not included.