Patent ID: 8614308

Claim:
An isolated nucleic acid molecule comprising a region encoding a polypeptide comprising a first immunoglobulin single variable domain and a second immunoglobulin single variable domain, wherein the CDR sequences of said first immunoglobulin variable domain (CDR(1) sequences) and the CDR sequences of said second immunoglobulin variable domain (CDR(2) sequences) are defined as follows: CDR(1)1: SEQ ID NO:17 CDR(1)2: SEQ ID NO:18 CDR(1)3: SEQ ID NO:19 CDR(2)1: SEQ ID NO:14 CDR(2)2: SEQ ID NO:15 CDR(2)3: SEQ ID NO:16, or CDR(1)1: SEQ ID NO:14 CDR(1)2: SEQ ID NO:15 CDR(1)3: SEQ ID NO:16 CDR(2)1: SEQ ID NO:17 CDR(2)2: SEQ ID NO:18 CDR(2)3: SEQ ID NO:19.