Patent ID: 7629473

Claim:
A compound of the general formula IV: wherein; R 1 -R 2 are independently selected from hydrogen, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; or R 1 and R 2 together with the nitrogen form a 4-7 membered ring containing zero or one double bond, optionally said ring in addition to said nitrogen comprises one further heteroatom selected from oxygen and sulphur; R 3 -R 6 and R 8 -R 12 are independently selected from hydrogen, halogen, cyano, nitro, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl, amino, C 1-6 -alk(en/yn)ylamino, di-(C 1-6 -alk(en/yn)yl)amino, C 1-6 -alk(en/yn)ylcarbonyl, aminocarbonyl, C 1-6 -alk(en/yn)ylaminocarbonyl, di-(C 1-6 -alk(en/yn)yl)aminocarbonyl, hydroxy, C 1-6 -alk(en/yn)yloxy, C 1-6 -alk(en/yn)ylsulfanyl, halo-C 1-6 -alk(en/yn)yl, halo-C 1-6 -alk(en/yn)ylsulfonyl, halo-C 1-6 -alk (en/yn)ylsulfanyl and C 1-6 -alk(en/yn)ylsulfonyl; R 7 is selected from hydrogen, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; X is selected from the group consisting of CH 2 , CHR 13 or CR 14 R 15 ; Y is selected from the group consisting of CH 2 , CHR 16 and CR 17 R 18 ; Z is selected from the group consisting of CH 2 , CHR 19 and CR 20 R 21 ; Q is selected from the group consisting of CH 2 , CHR 22 and CR 23 R 24 ; and m, n, o and p are independently 0 or 1; wherein m+n+o+p equals 1, 2, 3, or 4, with the proviso that when m+n+o+p equals to 1 then none of X, Y, Z and Q are CH 2 ; wherein R 13 - R 24 are independently selected from the group consisting of C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; or a pharmaceutically acceptable salt thereof.