Patent ID: 7927626

Claim:
A process for making a flowable hemostatic composition, comprising: introducing a volume of a biocompatible liquid into a double planetary mixer, introducing a volume of a biocompatible gas into said volume of liquid while said double planetary mixer is operating under conditions effective to mix said liquid and said gas together to form a foam comprising a discontinuous gas phase comprising said gas substantially homogenously dispersed throughout a continuous liquid phase comprising said liquid, introducing into said foam an amount of solid particles having average diameters from 40 to 1200 microns of a biocompatible polymer suitable for use in hemostasis and which is substantially insoluble in said liquid, at a ratio of from about 1:2 to about 1:12, based on grams particles/ml liquid; and mixing said foam and said solid particles together under conditions effective to form a substantially homogenous composition comprising said discontinuous gas phase and said particles substantially homogenously dispersed throughout said continuous liquid phase, wherein the ratio of said volume of liquid, said volume of gas and said amount of solid particles is effective to provide said substantially homogeneous composition with hemostatic properties, thereby forming said flowable hemostatic composition.