Patent ID: 7888330

Claim:
A compound of formula I: wherein R 1 is H, F, or (C 1 -C 4 )alkyl; X is F; R 4 is phenyl, optionally substituted with 1-3 nitro, 1-5 halo, 1-3 (C 1 -C 6 )alkyl, 1-2 CF 3 groups, or a combination thereof; R 2 and R 3 are individually H or (C 1 -C 6 )alkyl optionally substituted with 1 or 2 hydroxy, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkylthio, phenyl, (C 6 -C 12 )aryloxy, cyano, (C 1 -C 6 )alkoxycarbonyl, amido, (C 1 -C 6 )alkyl-amido, (C 1 -C 6 )alkylsulfonyl, (C 6 -C 12 )arylsulfonyl, (C 1 -C 6 )perfluoroalkyl-sulfonyl, (C 1 -C 6 )alkylsulfinyl, and (C 6 -C 12 )arylsulfinyl, or R 2 and R 3 taken together with N are a 5- or 6-membered heteroaryl or heterocyclic ring optionally containing 1 or 2 additional S, N, or O atoms, wherein N is substituted with R 5 , and R 5 is H, O, (C 1 -C 4 )alkyl, phenyl, or benzyl; with the proviso that one of R 2 and R 3 is not H; or a pharmaceutically acceptable salt thereof.