Patent ID: 7202245

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof wherein: R a and R b are, independently: (i) hydrogen; (ii) acetyl; (iii) —(C 1 –C 6 )alkyl, optionally, and independently, substituted with from 1–3 of: (a) halogen; (b) —NR 3 R 4 ; (c) —COR 5 ; (d) —OR 6 ; (e) aryl, optionally, and independently, substituted with from 1–3 of halogen; —(C 1 –C 6 )alkyl; or —(C 1 –C 6 )alkoxy; (f) heteroaryl, optionally, and independently, substituted with from 1–3 of trifluoromethyl or —(C 1 –C 6 )alkyl; (g) —(C 3 –C 11 )cycloalkyl; or (h) —(C 3 –C 11 )heterocycloalkyl, optionally, and independently, substituted with from 1–3 of —(C 1 –C 6 )alkyl or —(C 1 –C 6 )alkoxy; wherein: R 3 and R 4 are independently: (j) hydrogen; (k) amidino; (l) aryl, optionally, and independently, substituted with from 1–3 of halogen; cyano; nitro; —(C 1 –C 6 )alkyl, —(C 1 –C 6 )alkoxy, or —COR 5 ; (m) —(C 1 –C 6 )alkyl, optionally, and independently, substituted with from 1–3 of —(C 3 –C 11 )heterocycloalkyl; —(C 3 –C 11 )cycloalkyl; —(C 1 –C 6 )alkoxy; aryl; or heteroaryl; (n) heteroaryl, optionally, and independently, substituted with from 1–3 of halogen; trifluoromethyl; cyano; nitro; —COR 5 ; —(C 1 –C 6 )alkyl, optionally substituted with —(C3–C 11 )heterocycloalkyl; or —(C 1 –C 6 )alkoxy; (o) —(C 3 –C 11 )heterocycloalkyl, optionally substituted with from 1–3 of —(C 1 –C 6 )alkyl; or (p) —COR 5 ; R 5 is (q) hydroxy; (r) —(C 1 –C 6 )alkyl, optionally, and independently, substituted with from 1–3 of —(C 1 –C 6 )alkoxy or aryl; (s) —(C 1 –C 6 )alkoxy; (t) heteroaryl; or (u) —(C 3 –C 11 )heterocycloalkyl, optionally substituted with from 1–3 of —(C 1 –C 6 )alkyl; and R 6 is (v) —(C 1 –C 6 )alkyl, optionally, and independently, substituted with from 1–3 of —(C 1 –C 6 )alkoxy or aryl; (w) heteroaryl; or (x) —(C 3 –C 11 )heterocycloalkyl, optionally substituted with from 1–3 of —(C 1 –C 6 )alkyl; (iv) —(C 3 –C 11 )cycloalkyl; or (v) —(C 3 –C 11 )heterocycloalkyl, optionally, and independently, substituted with from 1–3 of halogen; —COR 5 ; —(C 1 –C 6 )alkyl; and —(C 1 –C 6 )alkoxy; or R a and R b , taken together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocycloalkyl ring, optionally having from 1–3 additional heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur, wherein said 5- or 6-membered heterocycloalkyl ring is optionally, and independently, substituted with from 1–3 of halogen; —(C 1 –C 6 )alkyl; or heteroaryl, optionally, and independently, substituted with from 1–3 of halogen; trifluoromethyl; and cyano; and R 1 and R 2 are independently selected from the group consisting of amino; halogen; hydrogen; trifluoromethyl; nitro; —COR 5 ; —NR 3 R 4 ; —CONR 3 R 4 ; and —(C 1 –C 6 )alkyl, optionally, and independently, substituted with from 1–3 of —(C 3 –C 11 )heterocycloalkyl; —NR 3 R 4 ; aryl; heteroaryl; or hydroxy; provided that when R a is hydrogen, and R b is hydrogen or isopropyl, R 1 is not halogen.