Patent ID: 8206896

Claim:
A method for differentiating human uterine leiomyosarcoma from human uterine leiomyoma using the degree of transcription or expression of LMP2 and cyclin E in uterine smooth muscle tissue as an indicator, wherein the method comprises: preparing a human uterine smooth muscle tissue from a patient who is suffering from a human uterine smooth muscle tumor as a sample; assaying transcription or expression of LMP2 and cyclin E in the human uterine smooth muscle tissue; and determining that the tumor is human uterine leiomyosarcoma when the LMP2 transcription or expression level is negative or lower than that in normal uterine smooth muscle tissue and the cyclin E transcription or expression level is positive or higher than that n normal uterine smooth muscle tissue to differentiate human uterine leiomyosarcoma from human uterine leiomyoma.