Patent ID: 7718659

Claim:
A compound of formula (I): R d —C(O)—N(R e )—R c —CH 2 —C(O)—N(R a )(R b ) (I) or a pharmaceutically acceptable salt thereof; wherein: R a and R b , together with the nitrogen atom to which they are attached, form piperazinyl-A-R b3 , wherein said piperazinyl is optionally substituted by halogen or C 1-6 alkyl; wherein: A is a bond or —CH 2 —C(O)—; and R b3 is selected from the group consisting of: (1) amino, optionally mono- or di-substituted by a substituent independently selected from the group consisting of C 1-6 alkyl, C 2-6 alkenyl and C 2-6 alkynyl, (2) aryl, (3) heteroaryl, (4) C 3-7 cycloalkyl and (5) heterocyclyl; wherein one or two carbon atoms of said aryl, heteroaryl, C 3-7 cycloalkyl or heterocyclyl is optionally replaced with a carbonyl group, and wherein said aryl, heteroaryl, C 3-7 cycloalkyl or heterocyclyl is optionally substituted by one or more substituents independently selected from the group consisting of: C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 alkoxy, halogen, cyano, nitro, amino, mono- or di-C 1-6 alkyl substituted amino, hydroxy, hydroxy C 1-6 alkyl, aminocarbonyl, mono- or di-C 1-6 alkyl substituted aminocarbonyl, halo C 1-6 alkyl, C 1-6 alkylsulfonyl, C 1-6 alkylsulfinyl, C 1-6 alkylthio, amino C 1-6 alkyl, mono- or di-C 1-6 alkyl substituted amino C 1-6 alkyl, aminosulfonyl, and mono- or di-C 1-6 alkyl substituted amino sulfonyl; R c is thiazole optionally substituted by one or more substituents independently selected from the group consisting of halogen and C 1-6 alkyl; and one or two carbon atoms of said thiazole is optionally replaced with a carbonyl group; R d is heteroaryl or heterocyclyl; wherein said heteroaryl or heterocyclyl is optionally substituted by one or more substituents independently selected from the group consisting of halogen, C 1-6 alkyl and C 1-6 alkoxy; R e is hydrogen or C 1-6 alkyl; and R f is hydrogen or C 1-6 alkyl.