Patent ID: 8426407

Claim:
A 1-(substituted phenyl)-5-trifluoromethyl-2(1H)pyridone compound, having a formula (XIII), wherein, R1-R4, and R12 are selected from: H, CN, NO 2 , a hydroxyl group, an amino group, a halogen atom, a C 1 -C 6 alkoxyl group, NR 10 R 11 , C(O)R 14 , O—C(O)R 14 , a C1-C6 alkyl group, a C 1 -C 6 haloalkyl group, a C 2 -C 6 alkenyl group, a carboxyl group and a carboxylic ether; wherein R 14 is a C 1 -C 6 alkyl group, R 10 and R 11 are selected from H, a C 1 -C 6 alkyl group, a C 1 -C 6 hydroxyalkyl group, an esterified C 1 -C 6 hydroxyalkyl group, a C 1 -C 6 alkoxyalkyl group, or formula XIV; and at least one of R1-R4, and R12 is NR 10 R 11 ; and at least one of R 10 and R 11 is of the formula XIV, and in formula XIV, R5 is selected from H, a C 1 -C 6 alkyl group, a C 1 -C 6 hydroxyalkyl group, an esterified C 1 -C 6 hydroxyalkyl group and a C 2 -C 6 alkenyl group; R6-R9 are selected from H, a C 1 -C 6 alkoxyl group, ═O, a C 1 -C 4 alkyl group, a C 1 -C 4 haloalkyl group, a C 1 -C 4 hydroxyalkyl group, and a C 2 -C 4 alkenyl group; X is selected from N or CH; Y is selected from N, O or C, with the proviso that, when Y is O, R 5 is absent; n is 1-6; and pharmaceutically acceptable salts thereof.