Patent ID: 8829033

Claim:
A compound of Formula Ib: wherein: R is: N(R′)OR′, CH 2 OCH 3 , CH 2 OCH 2 CH 3 , CH 2 OCH(CH 3 ) 2 , CH 2 OCD 3 , CH 2 OCD 2 CD 3 , CH 2 OCD 2 CH 3 , CH 2 OCD(CH 3 ) 2 , CH 2 OCD(CD 3 ) 2 , CH 2 OCF 2 H, CH 3 , CD 3 , CF 3 , CH 2 F, CH 2 CH 3 , (CH 2 ) 2 CH 3 , CH(CH 3 ) 2 , (CH 2 ) 3 CH 3 , C(CH 3 ) 3 ; each R′ is independently selected H or lower alkyl, unsubstituted or substituted with 1-3 electron-withdrawing or electron-donating groups; X′ is a covalent bond or a linker that consist of one, two, or three connected atoms and which atoms may or may not be substituted; Y′ is an aromatic or heteroaromatic moiety, unsubstituted or substituted with 1-3 electron-withdrawing or electron-donating groups; and Z′ is H, F, Cl, Br, I, CF 3 , CN, OCF 3 , or N 3 ; or a pharmaceutically acceptable salt or prodrug thereof.