Patent ID: 8859577

Claim:
A compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein R 1 is (C 1 -C 6 )alkyl, (C 3 -C 7 )cycloalkyl, tetrahydrofuranyl or oxetanyl; wherein said (C 1 -C 6 )alkyl is optionally substituted with 1 to 3 substituents independently selected from (C 1 -C 3 )alkoxy, hydroxy, fluoro, phenyl, tetrahydrofuranyl or oxetanyl; R 2 is hydrogen, halo, (C 1 -C 3 )alkyl, or cyano; R 3 are each independently hydrogen or (C 1 -C 3 )alkyl; L is a direct bond or a (C 1 -C 6 )alkylene wherein one carbon of the (C 1 -C 6 )alkylene is optionally replaced by —C(O)—, —C(O)NH—, —NHC(O)—, —O—, —S—, NH or N(C 1 -C 3 )alkyl; Z is CH 2 or O; A 1 and A 2 are each independently (C 6 -C 10 )aryl, 5 to 12 membered heteroaryl or 8 to 12 membered fused heterocyclicaryl; wherein said (C 6 -C 10 )aryl, 5 to 12 membered heteroaryl or 8 to 12 membered fused heterocyclicaryl are each optionally substituted with one to three substituents independently selected from (C 1 -C 3 )alkyl, (C 1 -C 3 )alkoxy, halo, amino, (C 1 -C 3 )alkylamino, di(C 1 -C 3 )alkylamino, hydroxy, cyano and amido wherein the alkyl portion of the (C 1 -C 3 )alkyl, (C 1 -C 3 )alkoxy, (C 1 -C 3 )alkylamino and di(C 1 -C 3 )alkylamino are optionally substituted with one to five fluoro; and wherein one of A 1 or A 2 is substituted by CO 2 R 4 , (C 1 -C 6 )CO 2 R 4 , tetrazolyl or (C 1 -C 6 )tetrazolyl; and R 4 is (C 1 -C 8 )alkyl, (C 3 -C 8 )cycloalkyl or (C 1 -C 6 )alkyl-(C 3 -C 8 )cycloalkyl; or a pharmaceutically acceptable salt thereof.