Patent ID: 7304087

Claim:
Compounds of Formula (Ia): wherein: A represents hydroxy; D represents aryl; E represents heteroaryl or heterocyclyl; G represents hydrogen or C 1-6 alkyl optionally substituted by one or more substituents selected from halo, OR 1 , SR 1 , C(O)NR 2 R 3 , CO 2 H, C(O)R 4 , CO 2 R 4 , NR 2 R 3 , NHC(O)R 4 , NHCO 2 R 4 , NHC(O)NR 5 R 6 , SO 2 NR 5 R 6 , SO 2 R 4 , nitro, cyano, aryl, heteroaryl and heterocyclyl; R 1 represents hydrogen, C 1-6 alkyl, arylalkyl, or heteroarylalkyl; R 2 and R 3 are independently selected from hydrogen, C 1-6 alkyl, aryl and heteroaryl; or R 2 and R 3 together with the nitrogen atom to which they are attached form a 5 or 6 membered saturated cyclic group; R 4 is selected from the group consisting of C 1-6 alkyl, aryl, heteroaryl, arylalkyl, and heteroarylalkyl; R 5 and R 6 are independently selected from the group consisting of hydrogen, C 1-6 alkyl, aryl, heteroaryl, arylalkyl, and heteroarylalkyl; or R 5 and R 6 together with the nitrogen atom to which they are attached form a 5 or 6 membered saturated cyclic group; and J represents C 1-6 alkyl, heterocyclylalkyl, arylalkyl or heteroarylalkyl; and salts, solvates and esters thereof; provided that when A is esterified to form —OR where R is selected from straight or branched chain alkyl, aralkyl, aryloxyalkyl, or aryl, then R is other than tert-butyl.