Patent ID: 7956088

Claim:
A pharmaceutical composition comprising an effective amount of a compound or a pharmaceutically acceptable salt or hydrate thereof in combination with a physiologically acceptable carrier, wherein the compound has one of the following structures: wherein R 1 -R 4 taken independently are a hydrogen atom or a group or grouping selected from the group consisting of alkyl, substituted alkyl, ally, substituted allyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, phenyl, substituted phenyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, halo, hydroxyl, alkoxy, substituted alkoxy, alloxy, phenoxy, substituted phenoxy, aroxy, substituted aroxy, alkylthio, substituted alkylthio, phenylthio, substituted phenylthio, arylthio, substituted arylthio, cyano, isocyano, substituted isocyano, carbonyl, substituted carbonyl, carboxyl, substituted carboxyl, amino, substituted amino, amido, substituted amido, sulfonyl, substituted sulfonyl, sulfonic acid, phosphoryl, substituted phosphoryl, phosphonyl, substituted phosphonyl, polyaryl, substituted polyaryl, C1-C20 cyclic, substituted C1-C20 cyclic, heterocyclic, substituted heterocyclic, aminoacid, peptide, and polypeptide groups, wherein at least one of R 1 or R 2 in Formula Ib is hydrogen; Z is a heteroatom selected from the group consisting of oxygen, sulfur, and nitrogen groupings; and X is a heteroatom selected from the group consisting of oxygen, sulfur, and nitrogen groupings.