Patent ID: 8877060

Claim:
A method for removing pathogens from a platelet preparation prior to transfusion, comprising: Passing said platelet preparation through a first tangential flow filtration (TFF) device having a TFF filter with an average pore size in the range of 0.2 μm to 5 μm, said TFF filter has a retentate side and a permeate side, wherein said platelet preparation comprises a platelet activation inhibitor and an anticoagulant, said platelet activation inhibitor comprises a short to ultra-short GPIIb/IIIA inhibitor and said anticoagulant comprises a short to ultra-short acting factor Xa inhibitor; and Collecting retentate from said first TFF device, wherein said retentate comprises filtered platelets to be used for transfusion, Wherein a diafiltration solution is added to said retentate.