Patent ID: 7534791

Claim:
A compound of the general formula IV: wherein; U is sulphur; R 1 -R 2 are independently selected from the group consisting of hydrogen, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; or R 1 and R 2 together with the nitrogen to which they are attached form a 4-7 membered ring containing zero or one double bond, optionally said ring in addition to said nitrogen comprises one further heteroatom selected from oxygen and sulphur; R 3 -R 6 are independently selected from the group consisting of hydrogen, halogen, cyano, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl, halo-C 1-6 -alk(en/yn)yl, halo-C 3-8 -cycloalk(en)yl and halo-C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; R 7 is selected from the group consisting of hydrogen, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; R 8 -R 11 are independently selected from the group consisting of hydrogen, halogen, cyano, C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl, C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl, halo-C 1-6 -alk(en/yn)yl, halo-C 3-8 -cycloalk(en)yl, halo-C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl, nitro, amino, C 1-6 -alk(en/yn)ylamino, di-(C 1-6 -alk(en/yn)yl)amino, C 3-8 -cycloalk(en)ylamino, C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)ylamino, hydroxy, C 1-6 -alk(en/yn)yloxy, C 3-8 -cycloalk(en)yloxy, C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yloxy, C 1-6 -alk(en/yn)ylsulfanyl, C 3-8 -cycloalk(en)ylsulfanyl and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)ylsulfanyl; m+n+o+p equals to 1, wherein m, n, o, and p are independently 0 or 1; X is selected from the group consisting of CH 2 , CHR 12 and CR 13 R 14 ; Y is selected from the group consisting of CH 2 , CHR 15 and CR 16 R 17 ; Z is selected from the group consisting of CH 2 , CHR 18 and CR 19 R 20 ; and Q is selected from the group consisting of CH 2 , CHR 21 and CR 22 R 23 ; wherein R 12 -R 23 are independently selected from the group consisting of C 1-6 -alk(en/yn)yl, C 3-8 -cycloalk(en)yl and C 3-8 -cycloalk(en)yl-C 1-6 -alk(en/yn)yl; or a pharmaceutically acceptable salt thereof.