Patent ID: 8658614

Claim:
An isolated nucleic acid molecule that selectively binds to an E-selectin protein and comprises a contiguous 29-30 nucleotide sequence that includes at least one monothiophosphate or a dithiophosphate modified nucleotide and which contains at least one motif selected from the group consisting of ACTYCWCYTCAC (SEQ ID NO.: 18), TCCTC (SEQ ID NO.: 50), TCCGTT (SEQ ID NO.: 51), TCCCCK (SEQ ID.: 52), ACCCWM (SEQ ID NO.: 53), ACTHC (SEQ ID NO.: 54), TCCCK (SEQ ID NO.: 55), ATCC (SEQ ID NO.: 56), CCGTY (SEQ ID NO.: 57) and CTTCW (SEQ ID NO.: 58), wherein Y=T or C, W=A or T, K=T or G, and M=A, or C, or has the nucleotide sequence of SEQ ID NO.: 31.