Patent ID: 8906888

Claim:
A compound selected from a compound of Formula 1, and pharmaceutically acceptable salts thereof: wherein R 1 is selected from the group consisting of C 1-6 alkyl, C 2-6 alkenyl, cyclo(C 3 -C 6 )alkyl and cyclo(C 3 -C 6 )alkenyl, with C 1-6 alkyl and C 2-6 alkenyl being unsubstituted or substituted with one or more halo groups or with 1-4 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, NH 2 , NHC 1-4 alkyl and N(C 1-4 alkyl)(C 1-4 alkyl), and with cyclo(C 3 -C 6 )alkyl and cyclo(C 3 -C 6 )alkenyl being unsubstituted or substituted with 1-5 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, CF 3 , OCF 3 , halo, SH, SC 1-4 alkyl, NH 2 , NHC 1-4 alkyl, N(C 1-4 alkyl)(C 1-4 alkyl), CN, C(O)OH, C(O)OC 1-4 alkyl, C(O)NHC 1-4 alkyl, NHC(O)C 1-4 alkyl, OC(O)C 1-4 alkyl, SOC 1-4 alkyl, SO 2 C 1-4 alkyl, SO 2 NHC 1-4 alkyl and SO 2 NH 2 ; R 2 is selected from the group consisting of H, C 1-6 alkyl and C 2-6 alkenyl, with C 1-6 alkyl and C 2-6 alkenyl being unsubstituted or substituted with one or more halo groups or with 1-4 groups independently selected from C 1-4 alkyl, OC 1-4 alkyl, OH, halo, NH 2 , NHC 1-4 alkyl and N(C 1-4 alkyl)(C 1-4 alkyl); R 3 is selected from the group consisting of OH, OC 1-6 alkyl, and halo; and R 4 are either both H or together form ═CH 2 .