Patent ID: 6855722

Claim:
A compound having the Formula IV: wherein: R 1 , R 2 , R 3 , R 4 and R 5 independently represent hydrogen, halogen, akyl, aryl, aralkyl, heteroaryl or heteroarylalkyl; R 6 , R 7 , R 8 and R 9 independently represent hydrogen, alkyl, hydroxyalkyl, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, carboxyalkyl, aryl or aralkyl; or R 6 and R 7 are taken together to form —(CH 2 ) p —, where p is 2-8, while R 8 and R 9 are defined as above; or R 8 and R 9 are taken together to form —(CH 2 ) q —, where q is 2-8, while R 6 and R 7 are defined as above; or R 6 and R 8 are taken together to form —(CH 2 ) r —, while r is zero (a bond), 1 or 2, while R 7 and R 9 are defined as above; X represents oxygen, sulfur, —CH 2 —, —NH—, —(C═O)NH— or —NH(C═O)—; n is from 0 to 4; m is from 0 to 4; a is 0 or 1; D represents oxygen; v is 0 or 1; R 10 , R 11 , R 12 and R 13 independently represent: hydrogen; hydroxy; alkyl; alkoxy; cycloalkyl; aryl, optionally substituted with one or more of halogen, hydroxy, cyano, alkyl, aryl, alkoxy, haloalkyl, arylalkyl, arylalkoxy, aryloxy, alkylsulfonyl, alkylsulfinyl, alkylalcoxyaryl, monoalkylamino, dialkylamino, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, alkanoyl; monoalkylamino; dialkylamino; aminoalkyl; monoalkylaminoalkyl; dialkylaminoalkyl; alkanoyl; heteroaryl having 5-14 ring members, optionally substituted with one or more of halogen, hydroxy, cyano, alkyl, aryl, alkoxy, haloalkyl, arylalkyl, arylalkoxy, aryloxy, alkylsulfonyl, alkylsulfinyl, alkylalkoxyaryl, monoalkylamino, dialkylamino, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, alkanoyl; or wherein R 17 and R 18 together form —CH 2 CH 2 —O—, —O—CH 2 CH 2 —, —O—CH 2 —O— or —O—CH 2 CH 2 —O—; or R 10 and R 12 are taken together to form —(CH 2 ) s —, wherein s is 0 (a bond) or 1 to 4, while R 11 and R 13 are as defined as above; or R 10 and R 12 are taken together to form a double bond when i is 0 and k is 1, while R 11 and R 13 are as defined above; or R 10 and R 11 are taken together to form —(CH 2 ) t —, wherein t is 2 to 8, while R 12 and R 13 are as defined as above, or R 12 and R 13 are taken together to form —(CH 2 ) u — wherein u is 2 to 8, while R 10 and R 11 are as defined as above; i is from 0 to 4; j is from 0 to 4; k is 0 or 1; R 14 is hydrogen, alkyl, aryl, aralkyl, dialkylaminoalkyl, 1-morpholinoalkyl, 1-piperidinylalkyl, pyridinylalkyl, alkoxy(alkoxy) alkoxyalkyl, or (alkoxycarbonyl)oxyethyl; W is: wherein: R 16 is hydrogen, alkyl, haloalkyl or halogen; and R 27 , R 28 , and R 29 are independently hydrogen, halogen, alkyl, alkoxy or aryl.