Patent ID: 7767687

Claim:
A compound having the structure: or pharmaceutically acceptable salt thereof; wherein A-B together represent: represents a single or double bond as valency permits; n is an integer from 0-4; R 1 and R 2 are independently hydrogen, halogen, cyano, nitro, or an aliphatic, heteroaliphatic, alicyclic, heteroalicyclic, aromatic or heteroaromatic moiety; R 3 is hydrogen, or an aliphatic, heteroaliphatic, alicyclic, heteroalicyclic, aromatic or heteroaromatic moiety; L 1 is —O—, —S—, —NR L1A — or a substituted or unsubstituted C 1-6 alkylene or C 2-6 alkenylene chain wherein up to two non-adjacent methylene units are independently optionally replaced by —C(═O)—, —CO 2 —, —C(═O)C(═O)—, —C(═O)NR L1A —, —OC(═O)—, —OC(═O)NR L1A —, —NR L1A NR L1B —, —NR L1A NR L1B C(═O)—, —NR L1A C(═O)—, —NR L1A CO 2 —, —NR L1A C(═O)NR L1B —, —S(═O)—, —SO 2 —, —NR L1A SO 2 —, —SO 2 NR L1A —, —NR L1A SO 2 NR L1B —, —O—, —S—, or —NR L1A —; wherein each occurrence of R L1A and R L1B is independently hydrogen, alkyl, heteroalkyl, heterocyclyl, aromatic, heteroaromatic or acyl; L 2 is a single bond, —O—, —S—, —NR L2A —, a heteroalicyclic or heteroaromatic moiety, or a substituted or unsubstituted C 1-6 alkylene or C 2-6 alkenylene chain wherein up to two non-adjacent methylene units are independently optionally replaced by —C(═O)—, —CO 2 —, —C(═O)C(═O)—, —C(═O)NR L2A —, —OC(═O)—, —OC(═O)NR L2A —, —NR L2A NR L2B —, —NR L2A NR L2B C(═O)—, —NR L2A C(═O)—, —NR L2A CO 2 —, —NR L2A C(═O)NR L2B —, —S(═O)—, —SO 2 —, —NR L2A SO 2 —, —SO 2 NR L2A —, —NR L2A SO 2 NR L2B —, —O—, —S—, or —NR L2A —; wherein each occurrence of R L2A and R L2B is independently hydrogen, alkyl, heteroalkyl, heterocyclyl, aromatic, heteroaromatic or acyl; Y is a divalent cycloalkyl, cycloalkenyl, heterocyclic, aryl or heteroaryl moiety; and Z is an aliphatic, heteroaliphatic, alicyclic, heteroalicyclic, aromatic or heteroaromatic moiety.