Patent ID: 8058300

Claim:
A compound having the structure of Formula (I) or a pharmaceutically acceptable salt thereof: wherein, R 1 is â€”CO 2 H, â€”CO 2 R D , â€”CN, â€”C(â•O)N(R 9 ) 2 , â€”C(â•O)NHCH 2 CH 2 SO 3 H, â€”C(â•O)NHSO 2 R 10 , tetrazolyl, or 5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl; R D is H or C 1 -C 4 alkyl; R 3 is H, C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, or C 1 -C 4 fluoroalkyl; R 4 is â€”NR 7 C(â•O)OCH(R 8 )â€”CY; R 7 is H or C 1 -C 4 alkyl; R 8 is H, C 1 -C 4 alkyl, or C 1 -C 4 fluoroalkyl; CY is a substituted or unsubstituted C 3 -C 6 cycloalkyl or a substituted or unsubstituted phenyl, wherein if CY is substituted then CY is substituted with 1 or 2 R C ; R 9 is H, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 6 cycloalkyl, or a substituted or unsubstituted phenyl; R 10 is a C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 6 cycloalkyl, or a substituted or unsubstituted phenyl; each of R A , R B , and R C are independently selected from F, Cl, Br, I, â€”CN, â€”OH, C 1 -C 4 alkyl, C 1 -C 4 -fluoroalkyl, C 1 -C 4 fluoroalkoxy, C 1 -C 4 alkoxy, and C 1 -C 4 heteroalkyl; m is 0, 1, or 2; n is 1, 2, 3 or 4; and p is 0, 1, or 2.