Patent ID: 7732398

Claim:
A method for inhibiting norepinephrine uptake in a mammal in need of analgesia, the method comprising administering to the mammal an effective amount of a selective mu-opioid receptor agonist peptide selected from the group consisting of: 2′,6′-dimethyl-Tyr-D-Arg-Phe-Lys-NH 2 ((Dmt 1 )DALDA); 2′,6′-dimethyl-Tyr-D-Ala-Phe-Phe-NH 2 ((Dmt 1 )TAPP); and 2′,6′-dimethyl-Tyr-D-Arg-Phe-Orn-NH 2 , wherein said effective amount is effective to reduce or inhibit norephinephrine uptake in the mammal.