Patent ID: 8597516

Claim:
A system for removing toxic substances from the blood of a patient and performing colloid exchange therapy, the system comprising: a removal interface for withdrawing blood from the patient; a very large pore hemofilter; a first tubing fluidly coupled to the removal interface and the very large pore hemofilter; wherein the very large pore hemofilter: has a membrane with pores for sieving, and the membrane is sized and configured to have pores with a sieving coefficient greater than or equal to 0.05 for albumin and a sieving coefficient of less than 0.03 for IgG so as to permit the passage of albumin while excluding the passage of immunoglobulins, so as to create a return stream and an ultrafiltrate stream, the return stream has retained molecules that did not pass through the pores and the ultrafiltrate stream has molecules that passed through the pores, a return tubing fluidly coupled to the very large pore hemofilter for receiving the return stream; an ultrafiltrate tubing fluidly coupled to the very large pore hemofilter for receiving the ultrafiltrate stream; a return interface for introducing the return stream into the patient; wherein the return tubing is also fluidly coupled to the return interface; a replacement fluid tubing; a control valve fluidly coupled to the replacement fluid tubing; and a fluid reservoir fluidly coupled to the return tubing, the fluid reservoir comprising fluids that contain clean target receptor molecules, including albumin, that are introduced into the patient, and wherein fluid reservoir is fluidly coupled to the return tubing via the replacement fluid tubing, and wherein the control valve on the replacement tubing is operable to regulate the flow of fluid containing albumin at a rate to maintain the patient's oncotic pressure.