Patent ID: 7259163

Claim:
A compound of formula (I) wherein: A represents OR 1 , NR 1 R 2 , or R 1 wherein R 1 and R 2 are independently selected from the group consisting of hydrogen, C 1-6 alkyl, aryl, heteroaryl, arylalkyl, and heteroarylalkyl; or R 1 and R 2 together with the nitrogen atom to which they are attached form a 5 or 6 membered saturated cyclic group; B represents C(O)R 3 wherein R 3 is selected from the group consisting of aryl and heteroaryl; C represents C 1-6 alkyl, aryl, heteroaryl or heterocyclyl; D represents a saturated or unsaturated 6-membered heterocyclic ring comprising three or more carbon atoms, each of which may independently be optionally substituted by R 4 and R 5 , and one to three heteroatoms independently selected from N, optionally substituted by hydrogen, C 1-6 alkyl, C(O)R 3 , SO 2 R 3 , aryl, heteroaryl, arylalkyl, or heteroarylalkyl; O; and S, optionally substituted by one or two oxygen atoms; wherein the 6 membered ring may be attached at any endocyclic carbon atom, and may be optionally fused to a saturated or unsaturated 5 or 6 membered carbocyclic or heterocyclic ring which may itself be optionally substituted on a non-fused carbon atom by C 1-6 alkyl, halo, OR 8 , C(O)NR 6 R 7 , C(O)R 3 , CO 2 H, CO 2 R 3 , NR 6 R 7 , NHC(O)R 3 , NHCO 2 R 3 , NHC(O)NR 1 R 2 , SO 2 NR 1 R 2 , SO 2 R 3 , nitro, cyano, oxo, aryl, heteroaryl and heterocyclyl; R 4 and R 5 are independently selected from hydrogen, C 1-6 alkyl, halo, OR 8 , C(O)NR 6 R 7 , C(O)R 3 , CO 2 H, CO 2 R 3 , NR 6 R 7 , NHC(O)R 3 , NHCO 2 R 3 , NHC(O)NR 1 R 2 , SO 2 NR 1 R 2 , SO 2 R 3 , nitro, oxo, aryl, heteroaryl and heterocyclyl; R 6 and R 7 are independently selected from hydrogen, C 1-6 alkyl, aryl and heteroaryl; and R 8 represents hydrogen, C 1-6 alkyl, arylalkyl, or heteroarylalkyl; E represents hydrogen or C 1-6 alkyl; F represents hydrogen, C 1-6 alkyl, aryl or heteroaryl; and G represents hydrogen, C 1-6 alkyl, heterocyclylalkyl, arylalkyl or heteroarylalkyl; and salts, hydrates and individual enantiomers thereof, provided that when A is OR 1 then R 1 is other than tert-butyl.