Patent ID: 7589238

Claim:
A method for treating hyperphosphatemia in an animal afflicted with renal insufficiency, the method comprising orally administering an effective amount of a phosphate binding polymer to the animal, the phosphate binding polymer being a crosslinked amine polymer comprising repeat units derived from polymerization of a non-polymeric amine and a crosslinking agent, the polymer having a swelling ratio of less than about 5 as measured in a physiological medium which is isotonic and neutral pH, the non-polymeric amine being (i) an amine of formula (I) wherein each n, independently, is equal to or greater than 3; m is equal to or greater than 1; and each R 1 , independently, is H or optionally substituted alkyl or aryl or is linked to a neighboring R 1 to form an optionally substituted alicyclic, aromatic, or heterocyclic group; or (ii) an amine of formula (IV) wherein each n, independently, is equal to or greater than 3; each r, independently, is 0, 1, or 2; and each R 1 , independently, is H or optionally substituted alkyl or aryl or is linked to a neighboring R 1 to form an optionally substituted alicyclic, aromatic, or heterocyclic group; provided the non-polymeric amine is not 1,3-diaminopropane or N,N′-(tetra-3-aminopropyl)-1,4-diaminobutane.