Patent ID: 7179836

Claim:
A compound of Formula (I): wherein: A is aryl, heteroaryl, heterocyclyl, —RR 3 , —C(O)OR 4 , —C(O)NR 5 R 6 , or —C(O)R 4 , wherein the aryl, heteroaryl, and heterocyclyl may optionally be substituted; D is hydrogen, C 1 –C 6 alkyl, halo, aryl, heteroaryl, heterocyclyl, —RR 3 , —C(O)OR 4 , —C(O)NR 5 R 6 , or —C(O)R 4 , wherein the alkyl, aryl, heteroaryl, and heterocyclyl may optionally be substituted; R is independently selected from C 1 –C 6 alkylene, C 2 –C 6 alkenylene, or C 2 –C 6 alkynylene, wherein the alkylene, alkenylene, and alkynylene may optionally be substituted; R 1 is hydrogen, C 1 –C 6 alkyl, C 3 –C 7 cycloalkyl, C 1 –C 6 alkoxy, C 3 –C 7 cycloalkoxy, aryl, heteroaryl, aralkyl, aryloxy, heterocyclyl, —C(O)OR 7 , or —C(O)NR 7 R 7 , where both R 7 are not simultaneously H, and wherein the alkyl, cycloalkyl, alkoxy, cycloalkoxy, aryl, heteroaryl, aralkyl, aryloxy and heterocyclyl may optionally be substituted; R 3 is independently selected from halo, C 1 –C 6 alkyl, C 3 –C 7 cycloalkyl, C 1 –C 6 haloalkyl, C 1 –C 6 alkoxy, C 3 –C 7 cycloalkoxy, C 1 –C 6 haloalkoxy, aryl, aralkyl, aryloxy, heteroaryl, heterocyclyl, —CN, —NHC(O)R 4 , —NHC(S)R 4 , —NR 5 R 6 , RNR 5 R 6 , —SR 4 , —S(O) 2 R 4 , —RC(O)OR 4 , —C(O)OR 4 , —C(O)R 4 , —C(O)NR 5 R 6 , —NHS(O) 2 R 4 , —S(O) 2 NR 5 R 6 , or —NHC(═NH)R 4 ; wherein the alkyl, cycloalkyl, haloalkyl, alkoxy, cycloalkoxy, haloalkoxy, aryl, aralkyl, aryloxy, heteroaryl, and heterocyclyl may optionally be substituted; R 4 is independently selected from hydrogen, C 1 –C 6 alkyl, aryl, heteroaryl, heterocyclyl, —RR 3 , —NR′″R″″, or —NR′NR′″R″″; wherein the alkyl, aryl, heteroaryl, and heterocyclyl may optionally be substituted; R 5 is independently selected from hydrogen, C 1 –C 6 alkyl, C 3 –C 7 cycloalkyl, cyanoalkyl, —R′R″, aryl, aralkyl, heteroaryl, —NHC(O)OR′″, —R′NHC(O)OR′″, —R′NHC(O)NR′″R″″, or —R′C(O)OR′″; wherein the alkyl, cycloalkyl, cyanoalkyl, aryl, aralkyl, and heteroaryl may optionally be substituted; R 6 is independently selected from hydrogen, C 1 –C 6 alkyl, C 3 –C 7 cycloalkyl, cyanoalkyl, —R′R″, aryl, aralkyl, heteroaryl, —C(O)OR′″, or —R′C(O)NR′″R′″; wherein the alkyl, cycloalkyl, cyanoalkyl, aryl, aralkyl, and heteroaryl may optionally be substituted; R 7 is independently selected from hydrogen, C 1 –C 6 alkyl, or aryl, wherein the alkyl and aryl may optionally be substituted; R′ is independently selected from optionally substituted C 1 –C 3 alkylene; R′ is independently selected from optionally substituted heteroalkyl or NR′″R″″; R″ is independently selected from hydrogen, C 1 –C 6 alkyl, aryl, aralkyl, heteroaryl, or C 3 –C 7 cycloalkyl; wherein the alkyl, aryl, aralkyl, heteroaryl, and cycloalkyl may optionally be substituted; and R″″ is independently selected from hydrogen, C 1 –C 6 alkyl, aryl, heteroaryl, or C 3 –C 7 cycloalkyl; wherein the alkyl, aryl, heteroaryl, and cycloalkyl may optionally be substituted; or a salt, solvate, or physiologically functional derivative thereof.