Patent ID: 8653049

Claim:
A compound of Formula I or Formula II wherein R 1 , R 4 , R 5 , R 6 and R 7 are each independently selected from hydrogen, acetyl, C10-C80 hydrocarbyl, a lipid moiety and a lipid acyl moiety; R 2 is a hydroxyl, a hydrocarbyl, a lipid moiety, a lipid acyl moiety; or an amino hydrocarbyl group optionally substituted with a hydrocarbyl, a lipid moiety or a lipid acyl moiety; R 3 and R 8 are each independently selected from acetyl, a hydrocarbyl, a lipid moiety and a lipid acyl moiety; X is a peptide chain; wherein the compound contains a lipid acyl selected from: a) the formula R 10 —C(O)— wherein R 10 is a C10-C80 saturated or unsaturated and branched, cyclic or polycylic hydrocarbyl group; b) a mycolic acid compound of formula VI wherein R 11 is a C10 to C30 hydrocarbon group, and R 12 is a C20 to C70 hydrocarbon group optionally bearing one or more carbon-carbon double bonds, cyclopropane rings, keto, hydroxyl, alkoxy, acyloxy, and carboxylic ester groups; c) cholesteryl hemisuccinyl; or d) dihydrocholesteryl hemisuccinyl; and with the proviso that the compound is other than: (i) a compound of formula I with R 1 is 2-tetradecylhexadecanoyl, R 2 is —OH, R 4 and R 5 are hydrogen, R 8 is acetyl; and X is -L-Abu-D-isoGln-; and (ii) a compound of formula II with R 1 is 2-tetradecylhexadecanoyl, R 2 is —OH; R 3 and R 8 are acetyl, R 4 , R 5 , R 6 and R 7 are hydrogen; and X is -L-Abu-D-isoGln-.