Patent ID: 7172749

Claim:
A radiolabeled compound of a formula: wherein: Q1 is Xâ€”Y(â•O)-Z and Q2 is selected from the group consisting of hydrogen, halogen, alkoxy, hydroxy, thiohydroxy, thioalkoxy, alkylamino and amino, or Q1 is selected from the group consisting of hydrogen, halogen, alkoxy, hydroxy, thiohydroxy, thioalkoxy, alkylamino and amino and Q2 is Xâ€”Y(â•O)-Z; X is selected from the group consisting of â€”NR 1 â€”, â€”Oâ€”, â€”NHâ€”NR 1 â€”, â€”Oâ€”NR 1 â€”, NHâ€”CHR 1 â€”, â€”CHR 1 â€”NHâ€”, â€”CHR 1 â€”Oâ€”, â€”Oâ€”CHR 1 â€”, â€”CHR 1 â€”CH 2 â€” and â€”CHR 1 â€”Sâ€” or absent; Y is selected from the group consisting of a non-radioactive carbon and a radioactive carbon; Z is selected from the group consisting of â€”R 2 Câ•CHR 3 , â€”Câ‰¡Câ€”R 3 and â€”R 2 Câ•Câ•CHR 3 ; R a is selected from the group consisting of hydrogen or alkyl having 1â€“8 carbon atoms; A, B, C and D are each independently selected from the group consisting of hydrogen, a non-radioactive derivatizing group, and a radioactive derivatizing group, whereas said non-radioactive group is selected from the group consisting of halogen, alkyl, haloalkyl, hydroxy, alkoxy, carboxy, carbalkoxy, thiocarboxy, thiohydroxy, thioalkoxy, alkylsulfinyl, alkylsulfonyl, amino, diamino, carbamyl, dicarbamoyl, nitro and cyano, and said radioactive derivatizing group is selected from a radioactive bromine, a radioactive iodine and a radioactive fluorine; R 1 is selected from the group consisting of hydrogen, and substituted or non-substituted alkyl having 1â€“6 carbon atoms; R 2 is selected from the group consisting of hydrogen, halogen and alkyl having 1â€“6 carbon atoms; and R 3 is a substituted alkyl having 1â€“6 carbon atoms, which comprises a substituted amino group; provided that the compound comprises at least one radioactive atom.