Patent ID: 6875752

Claim:
A compound in all its possible isomeric forms as well as their mixtures of the formula wherein R 2 is selected from the group consisting of hydrogen, halogen, alkyl, alkenyl or alkynyl of up to 12 carbon atoms, —OH, —O-alkyl, —OCO-alkyl up to 18 carbon atoms, —O-aryl or —OCO-aryl of up to 15 carbon atoms, R 4 is selected from the group consisting of —CH 2 NH 2 , —CH 2 NHalkyl of up to 18 carbon atoms, —CH 2 N(alkyl1) (alkyl2), alkyl1 and alkyl 2 are individually alkyl of up to 18 carbon atoms or R 4 is selected from the group consisting of unsubstituted or substituted —CH 2 -guanidine, —CH 2 -amidine, —CH 2 -heterocycle, —CH 2 —NH-heterocycle, —CH 2 —NH-aryl or —CH 2 —NH-heteroaryl, R 5 is selected from the group consisting of of up to 24 carbon atoms, of up to 24 carbon atoms, —CH 2 N 3 , R 8 is hydrogen or alkyl of up to 4 carbon atoms, R 9 is selected from the group consisting of unsubstituted or substituted alkyl of up to 18 carbon atoms, carbocyclic or heterocyclic having 5 or 6 ring members, aryl or heteroaryl, R 8 and R 9 also being able to form with the nitrogen atom which carries them a substituted or unsubstituted heterocycle, or R 5 is selected from the group consisting of unsubstituted or substituted —CH 2 alkyl, —CH 2 -aryl, —CH 2 -heteroaryl, —CH 2 Oalkyl, —CO 2 alkyl, —CH 2 S-alkyl of up to 16 carbon atoms, —CH 2 S-aryl or —CH 2 S-heteroaryl, R 6 is selected from the group consisting of hydrogen, halogen, —OH, —O-alkyl, —OCO-alkyl of up to 18 carbon atoms, —S-alkyl, —S-aryl or —S-heteroaryl of up to 12 carbon atoms, all the hereinable defined alkyl, aryl, heteroaryl, carbocyclic and heterocyclic when substituted are by at least one member of the group consisting of halogen, hydroxyl, alkyl and alkoxy of 1 to 4 carbon atoms, phenyl or phenylalkyl, the phenyl being unsubstituted or substituted by at least one member of the group consisting of halogen, phenyl or alkyl of 1 to 4 carbon atoms; and carbocyclic of 4 to 6 members; R 7 is hydrogen or a free, etherified or esterified OH, and its non-toxic, pharmaceutically acceptable acid addition salts.