Patent ID: 8153693

Claim:
A method of treatment of the immune-inflammatory component of celiac disease comprising, administering to a patient in need thereof, a therapeutically effective amount of a composition comprising a compound of formula (I) or pharmaceutically acceptable salts or esters thereof wherein R 1 and R 2 , equal or different from each other, are selected from the group comprising —H or a linear or branched alkyl group having 1 to 6 carbons, Y and Z, equal or different from each other, are selected from the group comprising —H, —OH, —COOH, OR 3 , —CH(OR 3 )COOH, and wherein R 3 is selected from H, a linear or branched alkyl group having 1 to 6 carbons, wherein administration of the composition treats the disease, and wherein said compound is selected from the group consisting of: -(±) 3-(3′-aminophenyl)-2-hydroxy-propionic acid of formula 2-(4-aminophenyl)-2-methoxyacetic acid, 2-(3-aminophenyl)-2-ethoxyacetic acid, 2-(4-aminophenyl)-2-ethoxyacetic acid, 3-(4′-aminophenyl)-2-methoxypropionic acid of formula 3-(4′-aminophenyl)-2-ethoxypropionic acid of formula 3-(3′-aminophenyl)-2-methoxypropionic acid of formula and 3-(3′ aminophenyl)-2-ethoxypropionic acid of formula