Patent ID: 7968578

Claim:
A compound of Formula I or a pharmaceutically acceptable salt thereof, wherein: each of A, B and C is independently selected from CH and C(R 1 ); -D-E-F- is selected from the group consisting of: —C(R 5 )═C(R)—N—, —C(R)═N—C(R)—, —C(R)═N—N—, —N═C(R)—N—, —N═N—N—, —C(R) 2 —N═C—, —N(R)—C(R)═C—, —N(R)—N═C—, —O—N═C— and —S—N═C— wherein each R is independently selected from the group consisting of: hydrogen, C 1-4 alkyl, C 1-4 fluoroalkyl, C 1-4 alkoxy, C 1-4 fluoroalkoxy and acetyl; R 5 is selected from the group consisting of: hydrogen, halo, C 1-4 alkyl, C 1-4 fluoroalkyl, C 1-4 -alkoxy, C 1-4 -fluoroalkoxy and acetyl; X is a bond, —CH 2 — or —CH 2 —CH 2 —, and X may additionally be —S—when -D-E-F- is —C(R 5 )═N—C(R)—; Ar 1 and Ar 2 are independently selected from the group consisting of: C 3-6 cycloalkyl, aryl, heteroaryl and heterocyclyl, or a fused analog of C 3-6 cycloalkyl, aryl, heteroaryl and heterocyclyl, wherein Ar 2 is optionally substituted with one to three R 2 groups and Ar 1 is optionally substituted with one to three R 4 groups; and R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of: halo, C 1-4 alkyl, C 1-4 -fluoroalkyl, C 1-4 alkoxy, C 1-4 -fluoroalkoxy and acetyl.