Patent ID: 7153887

Claim:
A method of treating anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis in a patient resistant to corticosteroid treatment and at least one agent selected from the group consisting of cyclosphosphamide, azathioprine, mycophenolate mofetil, anti-thymocyte-globuline, methotrexate and immunoglobulin which comprises administering an effective amount of medicament comprising 15-deoxyspergualin or a pharmaceutically acceptable salt to said patient to treat said ANCA associated vasculitis, wherein said administration is performed in at least two treatment cycles and an interphase in which no drug is administered between the cycles; wherein each treatment cycle lasts from about 5 days to about 21 days; and wherein the interphase lasts from 10 days to 5 weeks.