Patent ID: 7220725

Claim:
A topical pharmaceutical composition, consisting of a pharmaceutically acceptable excipient, and an analgesic effective amount of a peptide comprising L-amino acids of the formula pGlu-X—Y-Z (I), wherein X is an amino acid selected from the group consisting of GLY, VAL, GLU, ASP, SER, ALA, ASN, GLN, ILE, LEU, PRO, LYS and ARG, Y is TRP or THR, and Z is any L-amino acid, or Z is null; wherein Z is any L-amino acid, one but not both of Y and Z is TRP, and when Z is null, Y=TRP, or a peptide thereof having a (C 2 –C 30 ) alkyl group attached thereto, wherein the topical pharmaceutical composition is formulated for topical administration.