Patent ID: 6890930

Claim:
A compound of the formula I in which R and R 1 are independently of each other H, A, OH, OA, OCH 2 —Ar, Hal, NH 2 , NHA, NA 2 , NO 2 , CN, C(O)R 2 , CONH 2 , CONHA, CONA 2 , COOH, COOA or SO 2 A, R 2 is H, R 3 H or —C(═NH)—NH 2 , R 4 is Ar, cycloalkyl, phenylalkyl or Het, Y is absent or is alkenyl having 2 to 4 carbon atoms, Z is absent or is phenylene, A is unbranched or branched alkyl having 1 to 6 carbon atoms, Ar is phenyl, naphthyl, biphenyl or benzofuranyl, which is unsubstituted or mono-, di- or trisubstituted by A, OH, OA, CF 3 , OCF 3 , Hal, CN, COOH, COOA, NH 2 , NHA, NA 2 , NO 2 , SO 2 NH 2 , SO 2 NAH or SO 2 NA 2 , Het is a saturated, partially or completely unsaturated mono- or bicyclic heterocyclic radical and having 5 to 10 ring members, and having 1 or 2 N and/or 1 or 2 S or O atoms, which is optionally mono- or disubstituted by A, Hal, OH, OA, CF 3 , OCF 3 , NH 2 , NHA, NA 2 , COOH, COOA, phenyl, which is unsubstituted or mono-, di- or trisubstituted by A, OH, OA, CF 3 , OCF 3 , Hal, CN, COOH, COOA, NH 2 , NHA, NA 2 , NO 2 , SO 2 NH 2 , SO 2 NAH or SO 2 NA 2 , thiophenyl, or bithiophenyl, which latter two groups are unsubstituted or mono-, di- or trisubstituted by A, OH, OA, CF 3 , OCF 3 , Hal, CN, COOH, COOA, NH 2 , NHA, NA 2 , NO 2 , SO 2 NH 2 , SO 2 NAH or SO 2 NA 2 , Hal is F, Cl, Br or I, n is 1, 2 or 3, and m is 0, 1, 2 or 3, with the proviso that if Z and Y are absent, then R 4 is not phenylalkyl, and if Z and Y are absent, R 4 is Phenyl or 4-methoxyphenyl, R, R 1 , R 2 and R 3 are H, then the sum of n and m is not 2 or 3, or a pharmaceutically acceptable salt or solvate thereof.