Patent ID: 8822688

Claim:
A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: R 1 is —CONH 2 ; R 2 and R 3 are bonded together to form a cycloalkyl ring or a monocyclic saturated hetero ring in which one cyclic atom is a hetero atom, which is condensed with the adjacent ring, wherein the cycloalkyl ring and the monocyclic saturated hetero ring may have bridge(s) and may have 1 to 5 substituent(s) selected from the group consisting of halogen, lower alkyl, mono-OH substituted lower alkyl, di-OH substituted lower alkyl, -lower alkylene amine, —O-lower alkyl, cyano, aryl, a heterocyclic group, and acyl; R 4 is a heterocyclic group which may have 1 to 5 substituents selected from the group consisting of lower alkyl, mono-OH substituted lower alkyl, di-OH substituted lower alkyl, —O-lower alkyl, -lower alkylene-(amine which may be protected), cyano, and halogen; R 5 is —H; A represents CH or CH 2 ; and a dotted line represents that the site may form a double bond.