Patent ID: 7119088

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt, solvate, ester, or amide thereof, wherein V represents —(CH 2 ) d (O) e —, —CO—, or —CH(C 1-6 alkyl)—; W is —O—, —S(O) a —, or —N(R 1 )— R 1 represents H, C 1-6 alkyl, (CH 2 ) b COR 2 , CO(CH 2 ) b NR 2 R 3 , SO 2 R 2 , (CH 2 ) c OR 2 , (CH 2 ) c NR 2 R 3 , or (CH 2 ) b het 1 ; het 1 represents a saturated or unsaturated heterocycle of from 3 to 8 atoms containing one or more heteroatoms selected from O, N, or S, optionally substituted with C 1-6 alkyl; X and Y independently represent H, C 1-6 alkyl, halogen, OH, CF 3 , OCF 3 , OR 4 ; Z represents —(CH 2 ) f (O) g —, —CO— or —CH(C 1-6 alkyl)—; Ring A represents a 4–7 membered, saturated N-containing heterocycle, optionally substituted with OH, and in which optionally at least one ring N is substituted with O; Ring B represents phenyl or a 4–7 membered unsaturated N-containing heterocycle, optionally substituted with OH, halogen, CN, CONH 2 , CF 3 , OCF 3 , and in which optionally at least one ring N is substituted with O; R 2 and R 3 independently represent H, C 1-6 alkyl [optionally substituted with OH, halogen, N(C 1-6 alkyl) 2 , or C 1-6 alkyloxy], C 1-6 alkyloxy, N(C 1-6 alkyl) 2 , or [C 3-8 cycloalkyl]; or R 2 and R 3 , together with the nitrogen atom to which they are attached independently represent a heterocycle of from 3 to 8 atoms, optionally substituted with C 1-6 alkyl; R 4 represents straight or branched C 1-6 alkyl; a and c independently represent 0, 1, or 2; b, e and g independently represent 0 or 1; and d and f independently represent 1 or 2.