Patent ID: 8501732

Claim:
A compound of formula I wherein: R is —C(═O)A, —C(═O)OA, —C(═O)NHA, —C(═N—C≡N)A, —C(═N—C≡N)NHA, or A; A is lower alkyl, phenyl, cycloalkyl, adamantyl, heterocycloalkyl, heteroaryl, or bicyclic heteroaryl, optionally substituted with one or more A 1 ; each A 1 is independently A 2 or A 3 ; each A 2 is independently hydroxy, halo, or oxo; each A 3 is independently lower alkyl, lower alkoxy, phenyl, benzyl, heterocycloalkyl, bicyclic heterocycloalkyl, heteroaryl, amino, lower alkyl amino, lower dialkyl amino, amido, lower alkyl ester, sulfonyl, sulfonamido, —C(═O), or —C(═O)O, optionally substituted with one or more halo, hydroxy, lower alkyl, lower alkoxy, phenyl, hydroxy cycloalkyl, amino, lower alkyl amino, lower dialkyl amino, carbamic acid tert-butyl ester, sulfonyl, lower alkyl sulfonyl heterocycloalkyl, or hydroxy lower alkyl; R′ is H or methyl; X is CX′; X′ is H or halo; X 1 is H, 2-oxazolyl, dimethyl amido, or lower alkyl ester; Y is CH or N; and Y 1 is H, halo, lower alkoxy, or halo lower alkyl; or a pharmaceutically acceptable salt thereof.