Patent ID: 6949661

Claim:
A process for the preparation of a compound of Formula (I). wherein: R 1 is a moiety R 2 is a moiety n is an integer of 1 and 3-9; m is an integer of 0 or 2; R 3 and R 4 are independently selected from the group consisting of hydrogen, alkyl of 1 to 10 carbon atoms, alkoxy of 1 to 10 carbon atoms, halogen, nitro, trifluoromethoxy, phenoxy optionally mono or di substituted, and benzyloxy optionally mono or di substituted; R 5 , and R 6 , are independently selected from the group consisting of hydrogen, alkyl of 1 to 10 carbon atoms, halogen, nitro, phenyl optionally mono or di-substituted, phenoxy optionally mono or di-substituted, trifluoromethyl, trifluoromethoxy, and methanesulphonyl wherein mono or di-substitutents of phenyl, phenoxy, or benzyloxy are independently selected from the group consisting of alkyl of 1 to 10 carbon atoms, alkoxy of 1 to 10 carbon atoms, halogen, nitro, trifluoromethyl, trifluoromethoxy, methanesulphonyl, and phenyl; or a pharmaceutically acceptable salt thereof, which comprises reacting a compound of the formula with an alkyne of the formula wherein LG is a leaving group in the presence of a base to give a compound of Formula (I) or a pharmaceutically acceptable salt thereof.