Patent ID: 8754123

Claim:
An aqueous ophthalmic pharmaceutical solution composition suitable for topical application to an eye of a human, comprising: a prostaglandin suitable for lowering intraocular pressure of the eye, the prostaglandin being in the composition at a concentration that is at least 0.001 w/v % but less than 0.01 w/v %; a surfactant in the composition at a concentration that is at least 0.03 w/v % but less than 0.3 w/v %, wherein: i. the surfactant is entirely ethoxylated and/or hydrogenated vegetable oil and the ethoxylated and/or hydrogenated castor oil is the only surfactant in the composition; and ii. the composition is free of benzalkonium chloride; and a polymeric quaternary ammonium compound in the composition at a concentration that is greater than 0.0003 w/v % but less than 0.003 w/v %; and water.