Patent ID: 7759389

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: m is from 0 to 3; p is 2; q is 0, 1 Or 2; Ar is optionally substituted aryl or optionally substituted heteroaryl; each R 1 is independently halo, alkyl, haloalkyl, heteroalkyl, cyano, —S(O) t —R a , —C(═O)—NR b R c , —SO 2 —NR b R c , —N(R d )—C(═O)—R e , —C(═O)N(R d )—, or —C(═O)—R e , where t is from 0 to 2, and R a , R b , R c , R d and R e each independently is hydrogen or alkyl, and; R 2 is n is from 1 to 3; R 3 and R 4 each independently is hydrogen or alkyl; R 5 and R 6 each independently is hydrogen or alkyl, or R 5 and R 6 together may form ═NR f wherein R f is hydrogen or alkyl; and R 7 and R 8 each independently is hydrogen or alkyl, or one of R 7 and R 8 is hydrogen and the other is an optionally substituted 5- or six membered heteroaryl or heterocyclyl containing one or two nitrogens, or R 7 and R 8 together with the nitrogen to which they are attached may form an amidinyl group, a urea group, a guanidinyl group, or a five- or six-membered heterocyclic ring that optionally includes an additional heteroatom selected from O, N and S and which is optionally substituted with amino, or one of R 7 and R 8 and one of R 5 and R 6 together with the atoms to which they are attached may form a five- or six-membered heterocyclic ring that optionally includes an additional heteroatom selected from O, N and S.