Patent ID: 7323567

Claim:
A compound of formula (Ia), or an enantiomer or a salt thereof: wherein R 1 is —(CH═CH) 0-1 —(C 6 or C 10 )aryl or —(CH═CH) 0-1 -5-, 6-, 9- or 10-membered heteroaryl, said aryl or heteroaryl being optionally substituted with one, two or three substituents, each independently selected from: (C 1-6 )alkyl optionally substituted with amino, halo, (C 1-6 )haloalkyl, hydroxy, (C 1-6 )alkoxy, (C 1-6 )alkylthio, nitro, azido, cyano, amino, (C 1-6 )alkylamino, di((C 1-6 )alkyl)amino, aryl and heteroaryl; R 2 is H, (C 1-6 )alkyl, hydroxy, halo, (C 1-6 )haloalkyl, amino, (C 1-6 )alkylamino, di((C 1-6 )alkyl)amino, or (C 2-6 )alkynyl; R 3 is (C 6 , C 10 or C 14 )aryl or 5-, 6-, 9- or 10-membered heteroaryl, each of which being optionally substituted with one, two or three substituents, each independently selected from: (C 1-6 )alkyl, halo, (C 1-6 )haloalkyl, hydroxy, (C 1-6 )alkoxy, (C 1-6 )alkylthio, nitro, amino, (C 1-6 )alkylamino, di((C 1-6 )alkyl)amino and COO(C 1-6 )alkyl; and R 4 and R 5 are each independently H or (C 1-6 )alkyl; or R 4 and R 5 are linked, together with the carbon atom to which they are attached, to form a (C 3-7 )cycloalkyl group; with the proviso that R 1 is not 2-methoxyphenyl, when R 2 is H, R 3 is 3,4-dimethoxyphenyl, R 4 is CH 3 and R 5 is CH 3 .