Patent ID: 8435520

Claim:
A method of suppressing the rejection and prolonging the survival of a xenograft from a pig transgenic for hDAF in a baboon or human recipient, the method comprising: administering to a baboon or human recipient of a porcine xenograft, pharmaceuticals comprising cyclosporine A, cyclophosphamide, a compound comprising mycophenolic acid, a pharmaceutically acceptable salt of mycophenolic acid, or a mycophenolic combination thereof, and a steroid comprising prednisolone, methylprednisolone, or a steroidal combination thereof; treating a bodily fluid of the baboon or human recipient extracorporeally to remove at least pre-formed xenoreactive antibodies using an immunoadsorbent column; and reintroducing the treated body fluid into the baboon or human recipient, thereby suppressing the rejection and promoting the survival of the porcine xenograft.