Patent ID: 8071632

Claim:
A compound of the formula: wherein: Y is cyano or â€”C(O)R a , further wherein: R a is: hydrogen, hydroxy, halo, amino, hydroxyamino, azido or mercapto; or alkyl (Câ‰¦12) , alkenyl (Câ‰¦12) , alkynyl (Câ‰¦12) , aryl (Câ‰¦12) , aralkyl (Câ‰¦12) , heteroaryl (Câ‰¦12) , heteroaralkyl (Câ‰¦12) , alkoxy (Câ‰¦12) , alkenyloxy (Câ‰¦12) , alkynyloxy (Câ‰¦12) , aryloxy (Câ‰¦12) , aralkoxy (Câ‰¦12) , heteroaryloxy (Câ‰¦12) , heteroaralkoxy (Câ‰¦12) , acyloxy (Câ‰¦12) , alkylamino (Câ‰¦12) , dialkylamino (Câ‰¦12) , alkoxyamino (Câ‰¦12) , alkenylamino (Câ‰¦12) , alkynylamino (Câ‰¦12) , arylamino (Câ‰¦12) , aralkylamino (Câ‰¦12) , heteroarylamino (Câ‰¦12) , heteroaralkylamino (Câ‰¦12) , alkylsulfonylamino (Câ‰¦12) , amido (Câ‰¦12) , alkylthio (Câ‰¦12) , alkenylthio (Câ‰¦12) , alkynylthio (Câ‰¦12) , arylthio (Câ‰¦12) , aralkylthio (Câ‰¦12) , heteroarylthio (Câ‰¦12) , heteroaralkylthio (Câ‰¦12) , acylthio (Câ‰¦12) , alkylsilyl (Câ‰¦12) , or a substituted version of any of these groups; R 2 is: hydroxy, halo, amino; or fluoroalkyl (Câ‰¦8) , alkenyl (Câ‰¦8) , alkynyl (Câ‰¦8) , aryl (Câ‰¦8) , heteroaryl (Câ‰¦8) , alkoxy (Câ‰¦8) , aryloxy (Câ‰¦8) , acyloxy (Câ‰¦8) , alkylamino (Câ‰¦8) , arylamino (Câ‰¦8) , amido (Câ‰¦8) , or a substituted version of any of these groups; or pharmaceutically acceptable salts, tautomers, or optical isomers thereof.