Patent ID: 6897287

Claim:
A peptide forming a linear epitope for a human autoantibody selected from the group of peptides of less than forty amino acids. wherein the sequence of the epitope begins with the amino acid numbered from the amino terminus followed by the listed amino acid sequence consisting of the Ro/SSA epitopes: 30, MNRLHRFL (SEQ ID NO:37), 37, LCFGSEGGT (SEQ ID NO:38), 38, CFGSEGGT (amino acids 2-9 of SEQ ID NO:38), 41, SEGGTYYIKEQ (SEQ ID NO:39), 42, EGGTYYIKEQ (amino acids 2-11 of SEQ ID NO:39), 44, GTYYIKEQ (amino acids 4-11 of SEQ ID NO:39), 44, GTYYI (amino acids 4-8 of SEQ ID NO:39), 76, EIKSFSQEGRT (SEQ ID NO:40), 78 KSFSQEGR (amino acids 3-10 of SEQ ID NO:40), 81, SQEGRTTKQ (SEQ ID NO:41), 84, GRTTKQEPM (SEQ ID NO:42), 106, STKQKAFKAV (amino acids 2-11 of SEQ ID NO:43), 105, ISTKQAAFKAVS (SEQ ID NO:43), 108, KQAAFKAV (amino acids 4-11 of SEQ ID NO:43), 111, AFKAVSEVC (SEQ ID NO:44), 126, FTFIQFKKDLKESMK (SEQ ID NO:45), 130, QFKKDLKE (amino acids 5-12 of SEQ ID NO:45), 138, SMKCGMWGRA (SEQ ID NO:46), 139, MKCGMWGRA (amino acids 2-10 of SEQ ID NO:46), 142, GMWGRALRKAIA (SEQ ID NO:47), 145, GRALRKAI (amino acids 4-11 of SEQ ID NO:47), 165, ALAVTKYKQRNGWSSHKDLLRLSH (SEQ ID NO:48), 169, TKYKQRNG (amino acids 5-12 of SEQ ID NO:48), 173, QRNGWSHK (amino acids 9-16 of SEQ ID NO:48), 182, LLRLSHLKPSS (SEQ ID NO:49), 184, RLSHLKPS (amino acids 3-10 of SEQ ID NO:49), 199, TKYITKGW (amino acids 3-10 of SEQ ID NO:71), 202, ITKGWKEV (amino acids 6-13 of SEQ ID NO:71), 210, HELYKEKA (SEQ ID NO:50), 212, LYKEKALSV (SEQ ID NO:51) 216, KALSVETEKLLKYL (SEQ ID NO:52), 222, TEKLLKYL (amino acids 7-14 of SEQ ID NO:52), 224, KLLKYLEA (SEQ ID NO:53), 229, LEAVEKIVKRTKDE (SEQ ID NO:54), 234, KVKRTKDE (amino acids 6-13 of SEQ ID NO:54), 257, HLLTNHLKSKEVWKALLQEMPL (SEQ ID NO:55), 263, LKSKEVWK (amino acids 7-14 of SEQ ID NO:55), 264, KSKEVWKA (amino acids 8-15 of SEQ ID NO:55), 265, SKEVWK (amino acids 9-14 of SEQ ID NO:55), 280 ALLRNLGKMTA (SEQ ID NO:56), 283, RNLGKMT (amino acids 4-10 of SEQ ID NO:56), 285, LGKMTANS (SEQ ID NO:57), 308, LCNEKLLKKARIHPFHI (SEQ ID NO:58), 313, LLKKARI (amino acids 6-12 of SEQ ID NO:58), 315, KKARIHPF (amino acids 8-15 of SEQ ID NO:58), 330, TYKTGHGLRGKLKWRPDE (SEQ ID NO:59), 331 YKTGHGL (amino acids 2-8 of SEQ ID NO:59), 352, ALDAAFYK (SEQ ID NO:60), 355, AAFYKTFKTVEPTGKRFLLA (SEQ ID NO:61), 379, ASMNQRVLGS (SEQ ID NO:62), 365, EPTGKRFL (amino acids 11-18 of SEQ ID NO:61), 398, AMCMVVTR (SEQ ID NO:63), 414, AFSDEMVP (SEQ ID NO:64), 420, VPCPVTTD (SEQ ID NO:65), 433, VLMAMSQI (SEQ ID NO:66), 445, TDCSLPMI (SEQ ID NO:67), 449, LPMIWAQKTNTPA (amino acids 3-15 of SEQ ID NO:68), 472, TFAGGVHPAI (SEQ ID NO:69), 472, TFAGGVHP (amino acids 1-8 of SEQ ID NO:69), 481, IALREYRKKMDIPAKL (SEQ ID NO:70), 484, REYRKKMD (amino acids 4-11 of SEQ ID NO:70).