Patent ID: 8618247

Claim:
A peptide, having an N-terminal and a C-terminal, said peptide comprising a first peptide region located N-terminal to a second peptide region, wherein said first peptide region is a heavy chain variable region of an antigen-binding site or a light chain variable region of an antigen-binding site, and said second peptide region has the sequence: 1) RIIIRRIRR (SEQ ID NO:2); 2) RAIARRIRR (SEQ ID NO:3); 3) RLLLRRLRR (SEQ ID NO:4); 4) RVVVRRVRR (SEQ ID NO:5); 5) RAAARRARR (SEQ ID NO:6); 6) RGGGRRGRR (SEQ ID NO:7); 7) RMMMRRMRR (SEQ ID NO:8); 8) RSSSRRSRR (SEQ ID NO:9); or 9) RTTTRRTRR (SEQ ID NO:10), wherein R is arginine, I is isoleucine, L is leucine, V is valine, A is alanine, G is glycine, M is methionine, S is serine and T is threonine.