Patent ID: 8623818

Claim:
A compound, or a tautomer or isomer thereof, or a pharmaceutically acceptable salt of said compound, tautomer, or isomer, said compound having the general structure shown in Formula (VI): wherein R 1 , R 2 , R 3 , L 1 , and Z are selected independently of each other and wherein: q is 0 to 1; L 1 is selected from the group consisting of —NH—, —N(CH 3 )—, —O(CH 2 )—, and —O—; R 1 is selected from the group consisting of: phenyl and naphthyl, wherein said phenyl and said naphthyl are each substituted with at least one group each independently selected from: halo, alkyl, haloalkyl, alkoxy, haloalkoxy, and cycloalkyl; R 2 is selected from the group consisting of: phenyl and naphthyl, wherein said phenyl and said naphthyl are each substituted with at least one group each independently selected from: halo, alkyl, haloalkyl, alkoxy, haloalkoxy, and cycloalkyl; Z is selected from the group consisting of —(CH 2 )—(CH(CH 3 ))—C(O)OH, —(CH 2 )—(CH 2 )—(CH 2 )—C(O)OH, —(CH 2 )—C(CH 3 ) 2 —C(O)OH, —(CH 2 )—C(CH 3 )(OH)—C(O)OH, —CH 2 —CH 2 —C(O)OH, —CH 2 —CH(OH)—C(O)OH, —CH(CH 3 )—CH 2 —C(O)OH, —CH 2 —CH(F)—C(O)OH, —CH 2 —CF 2 —C(O)OH, —CH(CH 3 )—CF 2 —C(O)OH, —CH 2 —CH 2 —CF 2 —C(O)OH, and R 3 is selected from H and alkyl.