Patent ID: 7452880

Claim:
A compound of the formula I: or a pharmaceutically acceptable salt thereof, wherein: R 1 is 2,4-difluorophenyl, 4-fluorophenyl, 3-fluorophenyl, 2-fluorophenyl, phenyl, 2-chlorophenyl, 3,4-difluorophenyl, 4-trifluoromethylphenyl, 3-trifluoromethylphenyl, 2-trifluoromethylphenyl, 4-methylphenyl, 4-methoxyphenyl, 3,4-dichlorophenyl, or 1,3-benzodioxol-5-yl; R 2 is phenyl optionally substituted with halo, alkyl, amino, alkoxy, haloalkyl, hydroxy, hydroxyalkoxy, alkylsulfanyl, alkoxyamino, heteroaryl, heterocyclyl, heterocyclylalkyl, heterocyclyloxy, heterocyclylalkoxy, aminoalkoxy, hydroxyalkylamino, hydroxyalkylaminoalkyl, aralkyloxy, or pyridylalkyloxy; R 3 is hydrogen or alkyl; X and Y are N and Z is CR 4 ; R 4 is hydrogen; A is O; k is 0 or 1; B is O, NR 8 , S(O) j , CH(OR 9 ), CH═CH, or C(═O), wherein j is 0, 1 or 2; and R 8 is hydrogen, alkyl, —C(—O)—R 10 , or —SO 2 R 5 , wherein R 10 is alkyl, hydroxy, alkoxy, amino, heteroalkyl, aryl, aralkyl, heteroaryl or heterocyclyl; and R 5 is alkyl; and R 9 is hydrogen or alkyl.