Patent ID: 8802136

Claim:
A storage-stable device for the release of an active agent to the skin or mucosa of a host, said device comprising: an outer patch including an adhesive layer having adhesive properties; an inner patch comprising an active agent layer containing an active agent and an active agent impermeable layer supporting the active agent layer, the active agent impermeable layer having a first surface in contact with the active agent layer and a second surface opposing the outer patch; a release liner having an opening interposed between the second surface of the active agent impermeable layer and the outer patch, the release liner releasably adhered to a first portion of the adhesive layer of the outer patch such that the opening exposes a second portion of the adhesive layer of the outer patch to the second surface of the active agent impermeable layer, and, wherein a portion of the second surface of the active agent impermeable layer is directly adhered to the second portion of the adhesive layer of the outer patch exposed by the opening in the interposed release liner prior to removal of the release liner for application of the device to the skin or mucosa of the host whereby there are no intermediate layers between the portion of the second surface of the active agent impermeable layer and the second portion of the adhesive layer of the outer patch, and a remaining portion of the second surface of the active agent impermeable layer is unadhered to the adhesive layer of the outer patch prior to removal of the release liner for application of the device to the skin or mucosa of the host as a result of the release liner being interposed therebetween; and the outer patch having a surface area greater than the surface area of the inner patch, whereby removal of the release liner adheres the remaining portion of the active agent impermeable layer to the adhesive layer of the outer patch and exposes another portion of the adhesive layer of the outer patch extending beyond the periphery of the inner patch for adhering the device to the skin or mucosa of a host.