Patent ID: 7745472

Claim:
A method of treatment for use in the therapy of breast cancer, prostate cancer, ovarian cancer or endometrial cancer comprising administration of a pharmaceutical composition comprising a compound of Formula IIId wherein i) E is an optional linker group; R is a 5-, 6- or 7-membered carbocyclic ring; P is an optionally substituted 5- or 6-membered heterocyclic ring containing 1 to 3 hetero atoms selected from the group consisting of N, O and S; Q is a polycyclic ring system: at least Q comprises a sulphamate group; and at least one of P, Q and R is optionally substituted by one or more halo atoms or ii) E is an optional linker group; R is a 5-, 6- or 7-membered carbocyclic P is an optionally substituted 5- or 6-membered heterocyclic ring containing 1 to 3 hetero atoms selected from the group consisting of N, O and S; Q is a 5-, 6- or 7-membered ring: at least Q comprises a sulphamate group; and at least one of P, Q and R is substituted by one or more halo atoms.