Patent ID: 8628508

Claim:
An adapter configured to couple a withdrawal spike with a multidose vial for maintaining sterility therein, the adapter comprising: a hollow body defined by an outer wall having a first end and a second end; a first retaining member at the first end adapted to irreversibly engage at least a portion of the multidose vial such that once the adapter has been engaged with the vial, it is permanently locked in place to prevent removal of the adapter from the vial; and a second retaining member at the second end adapted to irreversibly engage at least a portion of the withdrawal spike, such that the withdrawal spike is locatable in a predetermined position with respect to the multidose vial such that once the spike has been engaged with the adapter, it is permanently locked in place as to prevent removal of the spike from the adapter, wherein the adapter irreversibly couples the withdrawal spike to the multidose vial such that the sterility of the vial contents is maintained after withdrawal of a first and subsequent doses using first and subsequent injection devices.