Patent ID: 7112595

Claim:
A compound of Formula II or a pharmaceutically acceptable salt thereof: wherein X and Y are N, Z is O; Ar 1 is 2-pyridyl; Ar 2 is phenyl; and wherein at least one of the Ar 1 and Ar 2 moieties are substituted with one or more moieties selected from the group consisting of —F, —Cl, —Br, —I, —SR, —SOR, —SO 2 R, —SO 2 NRR′, —OCOR, —OCONRR′, —NRCOR′, —NRCO 2 R′, —CN, —CO 2 R, —CONRR′, —C(O)R, —CH(OR)R′, —CH 2 (OR), CF 3 , C 1 –C 10 alkyl, cycloalkyl, alkyl-aryl, heterocycloalkyl, and aryl; R and R′ are independently selected from the group consisting of H, CF 3 , C 1 –C 10 alkyl, cycloalkyl, alkyl-aryl, heterocycloalkyl, aryl; R and R′ may combine to form a ring; with the proviso that the compound is not 3-(2-Pyridyl)-5-(2-chlorophenyl)-1,2,4-oxadiazole or 3-(2-Pyridyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole.