Patent ID: 7855215

Claim:
A compound of Formula I: wherein p is 1, 2 or 3; m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; A is CR c , S, NR C or O, where R C is H or lower alkyl; X, and Y are N, and Z is C-R3; each R a and R d are independently selected from hydrogen and lower-alkyl; each R b is hydrogen or lower-alkyl; R 1 , R 2 and R 3 are each independently selected from hydrogen; C 1 -C 7 alkyl, amino; C 1 -C 4 -alkanoylamino, halo, and azo; R 4 is selected from halo-C 1 -C 7 alkyl, carboxy, C 1 -C 7 alkoxycarbonyl, hydroxy, etherified or esterified hydroxy, C 1 -C 7 alkoxy, phenyl, phenyl- C 1 -C 7 alkoxy, C 1 -C 7 alkanoyloxy, C 1 -C 7 alkanoyl, amino, mono- or di-substituted amino, amidino, ureido, mercapto, N-hydroxy-amidino, guanidino, amidino-C 1 -C 7 alkyl, sulfo, sulfamoyl, carbamoyl, cyano, cyano-C 1 -C 7 alkyl and nitro; G is a group Ar or represents CN; Ar is selected from: where R 5 , R 6 , R 7 , R 8 and R 9 are each independently selected from hydrogen, halo, hydroxyl, etherified or esterified hydroxy, cyano, azo, nitro; substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, amino, a carbocyclic group, a heterocyclic group or mono- or di-substituted amino, being substituted by a substituted or unsubstituted hydrocarbyl moiety, the hydrocarbyl moiety selected from lower alkyl, cycloalkyl, lower alkanoyl; or any two of -L-R 5 , -L-R 6 or -L-R 7 together form a lower alkylene-dioxy bridge bound via the oxygen atoms; or any two of -L-R 5 , -L-R 6 or -L-R 7 together form a five, six or seven membered heterocyclic ring, which may be substituted or unsubstituted, especially a substituted indazole ring; wherein the carb comprises C 3 to C 6 in chain carbon atoms and is substituted or unsubstituted; and wherein the heterocyclic group especially comprises five, six or seven in-chain atoms of which at least one is a heteroatom selected from N, O or S and is substituted or unsubstituted and wherein L is a covalent bond or a moiety which comprises 1, 2, 3 or 4 in-chain atoms selected from carbon, oxygen, sulphur and nitrogen or salts, esters, or N-oxides thereof.