Patent ID: 8048442

Claim:
An stent comprising: a device body having an outer surface; a first coating layer disposed over the outer surface of the device body comprising a hydrophobic polymer; and a second coating layer above the first coating layer, the second coating layer comprising a glycosaminoglycan which is covalently bound to at least one coating material, a second drug which is not a glycosaminoglycan, and either at least one hydrophobic polymer or at least one amphiphile; wherein the coating material in the second layer to which the glycosaminoglycan is bound is not the second drug; there are no coating layers above the second coating layer; the second drug in the second coating layer is ionic; and the second coating layer further comprises an ionic component to bind with the second drug, the ionic component being copoly(ethylene glycol-dimethylaminoethyl methacrylate).