Patent ID: 7285562

Claim:
A pharmaceutical composition useful for inhibiting the enzyme malonyl-CoA decarboxylase which comprises an effective amount of a member selected from the group consisting of compounds of the formula (I): wherein R 1 and R 2 are independently selected from hydrogen, hydroxyl, alkoxyl, phenoxyl, substituted phenoxyl, C 1 -C 12 substituted alkyl, C 1 -C 12 substituted alkenyl, C 1 -C 12 substituted alkynyl, phenyl, substituted phenyl, aryl, heteroaryl or form a 5 to 7 membered ring with each other; R 3 is selected from hydrogen, C 1 -C 12 alkyl, substituted C 1 -C 12 alkyl, phenyl, substituted phenyl, aryl or heteroaryl; X is C or N; Y is S or O; its corresponding enantiomers, diastereoisomers or tautomers, or a pharmaceutically acceptable salt, or a prodrug thereof in an pharmaceutically-acceptable carrier.