Patent ID: 8410133

Claim:
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: Ht is I-c: wherein any substitutable carbon in ring I-c is optionally substituted with —R 10 ; Ring D is phenyl, wherein the phenyl is optionally substituted with 1-5 —R 5 ; Z 1 is N; each R X , R Y , and R Z is independently H, halo, or C 1-6 aliphatic, wherein the aliphatic is optionally substituted with 1-5 groups selected from halo, —CN, and —OR; each R 10 is independently selected from haloC 1-6 alkyl, C 1-6 alkyl, halo, OR, C(═O)R, CO 2 R, COCOR, NO 2 , CN, S(O)R, SO 2 R, SR, N(R 4 ) 2 , CON(R 4 ) 2 , SO 2 N(R 4 ) 2 , OC(═O)R, N(R 4 )COR, N(R 4 )CO 2 R; each R 4 is independently selected from H, C 1-6 alkyl, or haloC 1-6 alkyl; each R 5 is independently selected from halo, haloC 1-6 alkyl, C 3-6 cycloalkyl, or C 1-6 alkyl; and each R is independently selected from H, C 1-6 alkyl, or haloC 1-6 alkyl.