Patent ID: 7951949

Claim:
A compound of formula (II): wherein: Y is selected from the group consisting of (1) hydrogen, (2) —C 1-3 alkyl, wherein said alkyl is optionally substituted with one or more halogen, (3) halogen, and (4) cyano; A is selected from the group consisting of (1) hydrogen, (2) —C 1-10 alkyl, R 2 is selected from the group consisting of: (1) (R 5 —SO 2 )N(R 6 )—, wherein R 5 is (a) —C 1-10 alkyl, wherein said alkyl is unsubstituted or substituted with one or more (i) halo, (ii) —OH, (iii) —CN, (iv) —O—C 1-10 alkyl, and (v) —C 1-10 alkyl; R 6 is selected from the group consisting of (a) hydrogen, (b) —C 1-10 alkyl, and (e) —C 6-10 aryl wherein said alkyl, is unsubstituted or substituted with one or more (i) halo, (ii) —OH, (iii) —CN, (iv) —O—C 1-10 alkyl, R 3 is wherein if the dotted line leading to Q 3 is absent, then Q 3 is selected from the group consisting of (a) —CH 2 — (c) —NR x —, wherein R x is selected from the group consisting of (i) hydrogen, (ii) —C 1-10 alkyl, (v) —C 3-8 cycloalkyl, (vi) —C 0-6 alkylene-C 6-10 aryl, and (viii) —CO 0-6 alkyl-C 3-8 cycloalkyl, and if the dotted line leading to Q 3 represents a bond, then Q 3 is —CH— or —CH 2 —CH—, if the dotted line leading to R y is absent, then R y is selected from the group consisting of (a) hydrogen, (b) —C 1-10 alkyl, and if the dotted line leading to R y represents a bond, then R y is selected from the group consisting of (a) ═CH—C 1-10 alkyl, (b) ═CH—C 0-6 alkyl-C 6-10 aryl, Q 4 is —CH 2 : R 4 is —(CH 2 ) s -Q 2 -(CH 2 ) t , wherein Q 2 is selected from the group consisting of (1) —O— (2) —O—C(═O)—, and (3) —C(═O)—O—, m is 1; n is 1; r is 0; s is 1; and t is 0 or 1; and pharmaceutically acceptable salts thereof, and individual enantiomers and diastereomers thereof.