Patent ID: 7981862

Claim:
A composition of formula II: wherein: X is a peptide chain that (i) has a minimum of three amino acid residues, (ii) has a maximum of about fifty amino acid residues, and (iii) binds specifically to a cell surface receptor, wherein X is selected from the group consisting of SEQ ID NOs: 7-19; R 1 is independently hydrogen, such that the terminal group is NH 2 ; R 4 is OH such that the terminal group is a carboxyl; R 5 is lysine; R 6 is lysine; Y is Hx-Hx-Hx covalently bonded to R 5 and Z; and Z is a non-signaling peptide chain that includes a heparin binding domain comprising an amino acid sequence that comprises (i) a minimum of one heparin binding motif, (ii) a maximum of about ten heparin binding motifs, and (iii) a maximum of about thirty amino acids, wherein Z is selected from the group consisting of SEQ ID NOs: 1-6.