Patent ID: 7605166

Claim:
A method for treating rheumatoid arthritis in a mammal in need thereof comprising administering in therapeutically effective amounts a combination therapy comprising methotrexate and a compound of Formula X below: wherein each X is independently fluoro, chloro or bromo; p is an integer from 0 to 3; R 1 and R 3 together with the nitrogen atom to which they are bound form an azetidinyl, pyrrolidinyl, pyrrolyl, 2,5-dihydopyrrol-1-yl, piperidinyl, or 1,2,3,6-tetrahydro-pyridin-1-yl; R 2 is selected from the group consisting of lower alkyl, lower alkenyl, and lower alkylenecycloalkyl; and pharmaceutically acceptable salts thereof.