Patent ID: 8275468

Claim:
A medical electrical lead comprising: a lead body including a proximal end configured to be coupled to a pulse generator and a distal end adapted to be implanted at an implantation site within a patient's heart; at least one conductor extending within the lead body from the proximal end to the distal end; at least one electrode located along the lead body and operatively coupled to the at least one conductor; a helical fixation member coupled to the distal end of the lead body and configured to engage cardiac tissue at the implantation site, the helical fixation member formed from a hollow tube defining a hollow extending through the hollow tube, an internal wall laterally dividing the hollow into a first internal reservoir in a distal region of the helical fixation member and a second internal reservoir in a proximal region of the helical fixation member, a first plurality of elution ports located along a length of the helical fixation member in fluid communication with the first internal reservoir, a second plurality of elution ports located along a length of the helical fixation member in fluid communication with the second internal reservoir and a sealed distal tip; a first therapeutic agent composition comprising a therapeutic agent and a first carrier contained within the first internal reservoir; and a second therapeutic agent composition comprising the therapeutic agent and a second carrier contained within the second internal reservoir; wherein one of the first and second carriers is selected for rapid release of the therapeutic agent and the other of the first and second carriers is selected for extended release of the therapeutic agent.