Patent ID: 7671076

Claim:
A compound of formula (I), or therapeutically suitable salt, ester or prodrug, thereof, wherein is a member selected from the group consisting of a single and double bond: A is a member selected from the group consisting of —C(O)—, —N(R a )—C(O)—, —C(O)—N(R a )—, N(R a )—, —N(R a )—S(O) 2 —, and —S(O) 2 —N(R a )—; D is a member selected from the group consisting of a bond, —C(O)—, —C(O)—N(R b )—, —N(R b )—, —N(R b )—C(O)—, —N(R b )—S(O) 2 —, —O—, and —S(O) 2 —N(R b )—; L is a member selected from the group consisting of a bond, —(CH 2 ) m —CR d R e —(CH 2 ) n —, aryl, cycloalkyl, and heterocycle; m and n are each independently 0, 1, 2, 3 or 4; R 1 is a member selected from the group consisting of aryl, alkyl, arylalkyl, cycloalkyl and heterocycle; R a and R b are each independently members selected from the group consisting of hydrogen, alkyl, arylalkyl and heterocyclealkyl and hydroxyalkyl; R d and R e are each independently members selected from the group consisting of hydrogen, alkyl, alkoxy, alkoxyalkyl, aryl, arylalkyl, halo, haloalkyl, heterocycle, heterocyclealkyl, hydroxy and hydroxyalkyl, and R d and R e taken together with the atom to which they are attached form cycloalkyl; and X is a member selected from the group consisting of —CH 2 —, —CHF—, —CF 2 —, —O—, —S— and —CH 2 O—.