Patent ID: 7521551

Claim:
A compound of formula IC: wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 12 , R 13 , R 14 , R 15 , and R 16 are independently selected from hydrogen, a halogen; unsubstituted or substituted alkyl, C 3 -C 6 cycloalkyl, acetyl, aryl, alkenyl, alkynyl, amide groups, or ester groups; NR 17 R 18 ; vinyl; N(R 17 )(R 18 )(R 19 ) + Z − ; CH═CHNR 17 R 18 ; CH 2 CH 2 NR 17 R 18 ; CH═CHN(R 17 )(R 18 )(R 19 ) + Z − ; CH 2 CH 2 N(R 17 )(R 18 )(R 19 ) + Z − ; CHOHCH 3 ; CHOR 17 CH 3 ; CN; OH; OR 17 ; CHO; CH═CHCO 2 R 17 ; (CH 2 ) n OH; (CH 2 ) n SH; (CH 2 ) n O-alkoxy; (CH 2 ) n SR 17 ; (CH 2 ) n OR 17 ; (CH 2 ) n CO 2 R 17 ; (CH 2 ) n CONHR 17 ; (CH 2 ) n CON(R 17 )(R 18 ); CO 2 R 17 ; CONHR 17 ; CONR 17 R 18 ; SR 17 ; SO 3 H; SO 3 R 17 ; SO 2 NHR 17 ; SO 2 N(R 17 )(R 18 ); and SO 2 N(R 17 )(R 18 )(R 19 ) + Z − ; R 15 may be additionally selected from a cycloalkyl, aromatic, or hetereoaromatic fused ring system; R 17 , R 18 , and R 19 are independently selected from hydrogen, a physiologically acceptable salt; and unsubstituted or substituted C 1 -C 6 alkyl, aryl, alkenyl, or alkynyl; Z − is a pharmaceutically acceptable ion; R 7 , R 8 , R 9 , R 10 , and R 11 are independently selected from hydrogen, an unsubstituted or substituted alkyl or aryl; n is an integer ranging from 1 to 4; M is two hydrogens or a metal ion selected from Ag, Al, Ce, Co, Cr, Cu, Dy, Er, Eu, Fe, Gd, Hf, Ho, In, La, Lu, Mg, Mn, Mo, Nd, Ni, Pb, Pd, Pr, Pt, Rh, Sb, Sc, Sm, Sn, Tb, Th, Ti, TI, Tm, U, V, Y, Yb, Zn, and Zr; provided that when R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 8 , R 10 , R 11 , R 12 , and R 13 are hydrogen, and R 9 is selected from the group consisting of hydrogen and OCH 3 , and M is Ni, and R 7 is selected from the group consisting of CH 3 , CO 2 tBu, CO 2 Et, CO 2 iPr, and CO 2 Bu, then R 14 , R 15 , and R 16 cannot simultaneously be C 6 H 4 X where X is selected from the group consisting of hydrogen and OCH 3 .