Patent ID: 8497255

Claim:
A compound having Formula I, or individual stereoisomeric forms thereof, or individual geometrical isomers, individual enantiomers, individual diastereoisomers, individual tautomers, individual zwitterions or a pharmaceutically acceptable salt thereof: wherein: R 1 is N or C—R 9 ; R 2 is H, C 1-10 alkyl, halogen, hydroxyl or —OC 1-10 alkyl; R 3 is aromatic heterocycle, non-aromatic heterocycle, cycloalkyl, cycloalkenyl or aryl; R 4 is independently H, halogen, —OC 1-10 alkyl, hydroxyl, C 1-10 alkyl, nitrile, NR 7 R 8 , C 2-6 alkenyl, C 2-6 alkynyl, aromatic heterocycle, non-aromatic heterocycle, cycloalkyl, cycloalkenyl or aryl; R 5 is H, halogen, —OC 1-10 alkyl, hydroxyl or C 1-10 alkyl; R 6 is H, C 1-10 alkyl, halogen, hydroxyl or —OC 1-10 alkyl; R 7 is H or C 1-10 alkyl; R 8 is H or C 1-10 alkyl; R 9 is H or C 1-10 alkyl; and a is 1, 2, 3, 4 or 5; with the proviso that the compound is not of formula