Patent ID: 7396846

Claim:
A compound of the Formula I wherein: R1 is NHR10, (substituted or unsubstituted C 1 -C 6 alkyl)NHR10 or (unsubstituted or substituted C 3 -C 8 cycloalkyl)NHR10; R10 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 alkyl(OH), C 1 -C 6 alkylidenyl(OH)R11, or an amino protecting group; R11 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 1 -C 6 alkyl(O)C 1 -C 6 alkyl, C(O)O—C 1 -C 6 alkyl, aryl, or C 1 -C 6 alkylaryl; R2 is hydrogen, C 1 -C 6 alkyl, aryl, or C 1 -C 6 alkylaryl; R4 is hydrogen, C 1 -C 6 alkyl, aryl, C 1 -C 6 alkylaryl, or C 2 -C 6 alkenyl; R5 is hydrogen, aryl, C 1 -C 6 alkylaryl, hydroxy, C 1 -C 6 alkoxy or, unsubstituted or substituted C 1 -C 6 alkyl; R6 and R7 are independently hydrogen, unsubstituted or substituted C 1 -C 6 alkyl, unsubstituted or substituted C 2 -C 6 alkenyl, or R6 and R7 together with the carbon atom to which they are attached form a carbocyclic ring of up to 8 atoms which is optionally partly unsaturated or a substituted C 3 -C 8 cycloalkyl group which is optionally partly unsaturated; R8 is hydrogen, unsubstituted or substituted C 1 -C 6 alkyl, unsubstituted or substituted aryl, unsubstituted or substituted (C 1 -C 6 alkyl)C 3 -C 8 cycloalkyl, or unsubstituted or substituted C 1 -C 6 alkylaryl; Q is —S(O) 2 — or —C(O)—; m is a number selected from 1 or 2; R3 is substituted C 1 -C 6 alkylaryl, substituted C 1 -C 6 alkyl(O)—C 1 -C 6 alkylaryl, substituted C 3 -C 8 cycloalkyl, substituted (C 1 -C 6 alkyl)C 3 -C 8 cycloalkyl, or aryl substituted by at least one —SO 2 CF 3 group; and R9 is hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkenyl, cyano, optionally substituted aryl, optionally substituted —O-aryl, optionally substituted —N-aryl, optionally substituted —S-aryl, -aryl-aryl(K1)(K2), —O-aryl-aryl(K1)(K2), —N-aryl-aryl(K1)(K2), —S-aryl-aryl(K1)(K2), —O—C 1 -C 6 alkyl, or C 1 -C 6 alkylaryl, wherein K1 is halo or —CF 3 , and K2 is hydrogen, halo or —CF 3 or K1 and K2 together form a methylenedioxy group; or R3 is optionally substituted aryl, C 1 -C 6 alkylaryl, C 1 -C 6 alkyl(O)—C 1 -C 6 alkylaryl, C 3 -C 8 cycloalkyl, or (C 1 -C 6 alkyl)C 3 -C 8 cycloalkyl; and R9 is aryl substituted by at least one —SO 2 CF 3 group, —O-aryl substituted by at least one —SO 2 CF 3 group, —N-aryl substituted by at least one —SO 2 CF 3 group, or —S-aryl substituted by at least one —SO 2 CF 3 group; or a pharmaceutically acceptable salt thereof.