Patent ID: 7928140

Claim:
A compound of Formula V or a pharmaceutically acceptable salt thereof, wherein Q is X is S; A 1 is CH or C-halo; A 4 is CH or C-halo; A 5 is CR 3 or N; A 6 is CR 3 or N; A 7 is CR 3 or N; A 8 is CR 3 or N; provided that no more than three of A 5 , A 6 , A 7 and A 8 is N; each R 3 is independently H, C 1 -C 6 alkyl, halo, —OC 1 -C 6 alkyl, -Ohaloalkyl, —CN, or —CF 3 ; R 1 is H; R 2 is H, or C(O)R 7a , R 7a is C 1 -C 6 alkyl , —(CRR) n NR x R y , —(CRR) n aryl, —(CRR) n heteroaryl, —(CRR) n OR —(CRR) n heterocycloalkyl, —(CRR) n Ophenyl, —NR(CRR) n R x R y , or —S(O) 2 R; each R is independently H or C 1 -C 6 alkyl; each R X and R Y are independently hydrogen, or C 1 -C 6 alkyl, or R X and R Y together with the nitrogen atom to which they are attached form a 5 to 8 membered ring containing from 1 to 3 heteroatoms independently selected from N, O or S; each n is independently 0, 1, 2, 3 or 4; Y is —NRSO 2 (CRR) n aryl, —NRSO 2 C 1 -C 6 alkyl, or —NRSO 2 heteroaryl; wherein aryl or heteroaryl can be optionally substituted with from 1 to 4 substitutents selected from halo, C 1 -C 6 alkyl, —CF 3 , —CN, —OC 1 -C 6 haloalkyl, —OC 1 -C 6 alkyl, or C(O)C 1 -C 6 alkyl.