Patent ID: 6916811

Claim:
A compound having the structural formula A or a pharmaceutically acceptable salt of said compound, wherein: R is selected from the group consisting of R 1 -furanyl-, R 1 -thienyl-, R 1 -pyridyl-, R 1 -oxazolyl-, R 1 -pyrrolyl- and R 2 -aryl-; X is —(CH 2 ) n —; Y is a pyrrolidinyl or azepanyl group with an aryl or heteroaryl moiety fused to two adjacent carbon atoms on Y, Y is a piperidinyl group with a pyridyl, pyrimidyl or pyrido[4,3-b]pyridyl group fused to two adjacent carbon atoms on Y, or Y is a piperidinyl group with a phenyl moiety fused to two adjacent carbon atoms on Y, wherein the piperidinyl group fused to a phenyl moiety has a substituent Q other than hydrogen, wherein X is attached to the N atom of the piperidinyl, pyrrolidinyl or azepanyl group; Q is 1-4 substituents, which can be the same or different, and are independently selected from the group consisting of hydrogen, cycloalkyl, amino, aryl, aralkyl, heteroaryl, alkyl, CF 3 , CN, halogen, NO 2 , alkoxy, alkoxyalkoxy, cycloalkylalkoxy, alkylamino, alkylsulfonamino, alkylaminosulfonyl, dialkylaminosulfonyl, NH 2 SO 2 and hydroxy; n is 1 to 4; R 1 is 1-3 substituents, which may be the same or different, and are independently selected from the group consisting of hydrogen, alkyl, CF 3 , halogen and NO 2 ; and R 2 is 1-3 substituents, which may be the same or different, and are independently selected from the group consisting of hydrogen, alkyl, CF 3 , halogen, NO 2 , alkoxy, alkylamino, alkylsulfonamido, alkylaminosulfonyl, dialkylaminosulfonyl, aminosulfonyl, and hydroxyl.