Patent ID: 7297820

Claim:
A compound of general Formula III: or a pharmaceutically acceptable salt thereof, wherein: R 28 is hydrogen or C 1-4 alkyl, n is equal to a number from zero to four, Z is —CR 15 ═CR 16 —, wherein R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 24 and R 25 are independently selected from the group consisting of: a. hydrogen b. C 1-4 alkylthio, c. hydroxy, d. C 1-4 alkoxy, e. NR 26 R 27 , wherein R 26 and R 27 are hydrogen or C 1-4 alkyl, f. phenyl(C 1-4 )alkyl, g. C 6-10 aryl, h. heteroaryl, i. heterocycle, j. heterocycle(C 1-4 )alkyl, and k. C 3-6 cycloalkyl, wherein said phenyl(C 1-4 )alkyl, C 6-10 aryl, heteroaryl, heterocycle, heterocycle(C 1-4 )alkyl or C 3-6 cycloalkyl is substituted with one of the following: C 1-4 alkylthio, C 1-4 alkyl, methoxy, hydroxy, dimethylamino or methylamino; provided that one or more of R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 24 and R 25 is other than hydrogen; and, R P is hydrogen or a sulfur protecting group.