Patent ID: 8212077

Claim:
A process for the synthesis of a compound of formula (I) wherein 7-methoxy-1-naphthol of formula (II): is subjected to appropriate reaction conditions to convert the hydroxy function into a leaving group and then condensed, in the presence of palladium, with a compound of formula (III): CH 2 ═CH—R (III), wherein R represents wherein R′ and R″, which may be the same or different, each represent a linear or branched (C 1 -C 6 )alkyl group or R′ and R″ together form a (C 2 -C 3 )alkylene chain and the ring formed may be fused with a phenyl group, to yield a compound of formula (IV): wherein R is as defined hereinbefore, which is subjected to catalytic hydrogenation to yield a compound of formula (V): wherein R is as defined hereinbefore, which is subjected to base or acid hydrolysis or to a binary reducing agent/acid system to yield a compound of formula (VI) or its hydrochloride salt: which is successively subjected to the action of sodium acetate and then acetic anhydride to yield the compound of formula (I), which is isolated in the form of a solid.