Patent ID: 8614302

Claim:
A compound of the formula: and its salts, wherein R 3 is L-S c , wherein L is a direct bond, or a group of 1-20 nonhydrogen atoms selected from the group consisting of C, N, O, P and S and is composed of any combination of ether, thioether, amine, ester, carboxamide, sulfonamide, hydrazide, aromatic and heteroaromatic bonds, and S c is an IgG antibody, concanavalin A, transferrin, streptavidin, R-phycoerythrin, allophycocyanin, aminophalloidin, an aminodextran, wheat germ agglutinin, amine-derivatized polystyrene microspheres, 5-(3-aminoallyl)-2′-deoxyuridine 5′-triphosphate, 5-(3-amino-1-propynyl)-2′-deoxyuridine 5′-triphosphate, 2′-(or 3′)-2-aminoethylaminocarbonyladenosine 5′-triphosphate, or tyramine; R 4 is C 1 -C 22 alkyl or C 7 -C 22 arylalkyl, each alkyl portion of which optionally incorporates up to six hetero atoms, selected from N, O and S, and each alkyl portion of which is optionally substituted one or more times by F, Cl, Br, I, hydroxy, carboxy, sulfo, phosphate, amino, sulfate, phosphonate, cyano, nitro, azido, C 1 -C 6 alkoxy, C 1 -C 6 methyl or ethyl; R 2 is C 1 -C 22 alkyl or C 7 -C 22 arylalkyl, each alkyl portion of which optionally incorporates up to six hetero atoms, selected from N, O and S, and each alkyl portion of which is optionally substituted one or more times by F, Cl, Br, I, hydroxy, carboxy, sulfo, phosphate, amino, sulfate, phosphonate, cyano, nitro, azido, C 1 -C 6 alkoxy, C 1 -C 6 sulfopropyl or sulfobutyl; R 6 is H; R 7 is sulfo; R 8 is H; R 9 is H; R 16 is H; R 17 is sulfo; R 18 is H; R 19 is H; n is 1, 2 or 3; R 12 is C 1 -C 22 alkyl or C 7 -C 22 arylalkyl, each alkyl portion of which optionally incorporates up to six hetero atoms, selected from the group consisting of N, O and S, and each alkyl portion of which is optionally substituted one or more times by F, Cl, Br, I, hydroxy, carboxy, sulfo, phosphate, amino, sulfate, phosphonate, cyano, nitro, azido, sulfopropyl or sulfobutyl; R 13 is C 1 -C 22 alkyl or C 7 -C 22 arylalkyl, each alkyl portion of which optionally incorporates up to six hetero atoms, selected from the group consisting of N, O and S, and each alkyl portion of which is optionally substituted one or more times by substituents selected from the group consisting of F, Cl, Br, I, hydroxy, carboxy, sulfo, phosphate, amino, sulfate, phosphonate, cyano, nitro, azido, C 1 -C 6 alkoxy, C 1 -C 6 methyl; R 14 is C 1 -C 22 alkyl or C 7 -C 22 arylalkyl, each alkyl portion of which optionally incorporates up to six hetero atoms, selected from the group consisting of N, O and S, and each alkyl portion of which is optionally substituted one or more times by substituents selected from the group consisting of F, Cl, Br, I, hydroxy, carboxy, sulfo, phosphate, amino, sulfate, phosphonate, cyano, nitro, azido, C 1 -C 6 alkoxy, C 1 -C 6 methyl, and wherein sulfo is sulfonic acid or sulfonate.