Patent ID: 7538222

Claim:
A compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R 1 is an optionally substituted (heterocyclyl)C 1-6 -alkyl; R 2 and R 3 are independently selected from the group consisting of hydrogen, C 1-6 -alkyl and halogen or such that R 2 together with R 3 forms a 3-, 4-, 5-, 6-, or 7-membered ring system with the atoms of the piperidine ring; m is 1; n is selected from the group consisting of 1, 2, and 3; Ar 1 aryl or heteroaryl, optionally substituted with a substituent selected from the group consisting of C 1-6 -alkyl, C 1-6 -alkoxy, oxo, carboxyl, amino, hydroxy, nitro, alkylsulfonyl, alkylsulfenyl, alkylsulfinyl, C 1-6 -alkoxycarbonyl, C 1-6 -alkylcarbonyl, formyl, amino, mono- and di(C 1-6 -alkyl)amino, carbamoyl, mono- and di(C 1-6 -alkyl)aminocarbonyl, amino-C 1-6 -alkyl-aminocarbonyl, mono- and di(C 1-6 -alkyl)amino-C 1-6 -alkyl-aminocarbonyl, C 1-6 -alkylcarbonylamino, C 1-6 -alkylhydroxyimino, cyano, guanidino, carbamido, C 1-6 -alkanoyloxy, C 1-6 -alkylsulphonyloxy, dihalogen-C 1-6 -alkyl, trihalogen-C 1-6 -alkyl, haloalkoxy, heterocyclyl, halo, alkylamido, C 1-6 hydroxyalkyl, C 1-6 aminoalkyl, and sulfamoyl; W is selected from the group consisting of oxygen and sulfur; X is selected from the group consisting of optionally substituted methylene, optionally substituted ethylene, optionally substituted propylene, optionally substituted vinylene, and CH 2 N(R N ), wherein R N is selected from hydrogen and C 1-6 -alkyl; and Ar 2 is an optionally substituted aryl or heteroaryl.