Patent ID: 7771366

Claim:
A method for tissue bioassay comprising the following steps: a) placing in a vagina of a female human an elongated probe having at least two metallic electrodes positioned close to an insertion end of said elongated probe, none of said at least two electrodes extends around the entire periphery of said elongate probe, wherein said probe is positioned so that at least one of said at least two metallic electrodes contacts an epithelium of a cervix or a fornix of said vagina of said female human; b) applying across said at least two metallic electrodes contacting said epithelium an alternating voltage; c) measuring across said at least two metallic electrodes an epithelium responsive parameter; d) generating a value of said epithelium responsive parameter representative of a hormonal status of said epithelium of said female human, and wherein use of said metallic electrodes to measure said epithelium responsive parameter increases amplitude of said value as compared to use of non-metallic electrodes; e) comparing said value of said epithelium responsive representative of said hormonal status of said epithelium of said female human to a reference value; and f) predicting an occurrence of ovulation in said female human.