Patent ID: 8728758

Claim:
A method of measuring a metabolic activity (MA) of a cell, the method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products and volatile soluble metabolic products; (ii) non-volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein said measuring acidification profile of said (ii) is effected in an air-exposed chamber, and wherein said measuring acidification profile of said (i) is effected in an air-sealed chamber, and wherein said measuring acidification profile of said (iii) is by subtracting an acidification profile of said (ii) from an acidification profile of said (i), and further wherein all of said time dependent acidification profiles are indicative of the metabolic activity of the cell.