Patent ID: 8440220

Claim:
A transdermal system for administering an analgesic through the skin, the system having a reduced potential for abuse and including a multilaminate comprising: (a) an analgesic reservoir comprising an analgesic, the analgesic being selected from the group consisting of fentanyl and analogs thereof; (b) an antagonist reservoir layer comprising an antagonist for said analgesic, the antagonist reservoir layer comprising an external edge of the system; (c) a barrier layer, said barrier layer separating said antagonist reservoir layer from said analgesic reservoir, said barrier layer being impermeable to said analgesic and to said antagonist, wherein the system (i) has an antagonist release rate controlling layer that substantially prevents release of the antagonist from the system upon securing the system to a human patient for a period of up to about 7 days; and (ii) provides release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the system is subject to abuse, such that the antagonist reservoir layer releases the antagonist through the external edge of the antagonist reservoir layer.