Patent ID: 8178568

Claim:
A compound of formula I, wherein R 1 is aryl optionally independently substituted with 1 to 3 substituents chosen from C 1-6 alkyl, C 3-6 cycloalkyl, C 1-6 alkoxy, C 1-6 alkylthio, C 1-6 alkylsulfonyl, C 1-6 alkoxycarbonyl, C 1-6 alkylaminocarbonyl, C 1-6 acylamino, C 1-6 dialkylaminocarbonyl, halogen, cyano, nitro, aryl and heteroaryl; or R 1 is C 1-10 alkyl, C 3-6 cycloalkyl, 3-10 membered saturated heterocyclic ring, each optionally independently substituted with 1-3 substituents chosen from C 1-10 alkyl, C 3-10 cycloalkyl, C 1-6 acyl, cyano, phenyl, oxo, hydroxyl and halogen; each R 1 and R 1 substituent where possible is optionally substituted with 1 to 3 halogen atoms; or R 1 is C 1-6 alkyl substituted with 3-10 membered saturated heterocyclic ring each optionally independently substituted with 1-3 substituents chosen from C 1-10 alkyl, C 3-10 cycloalkyl, C 1-6 acyl, cyano, phenyl, oxo, hydroxyl and halogen; R 2 is hydrogen or C 1-6 alkyl; R 3 is heteroaryl optionally independently substituted with 1 to 3 substituents chosen from C 1-6 alkyl (which is optionally partially or fully halogenated) and halogen; R 4 is C 1-6 alkyl, aryl or heteroaryl each optionally independently substituted with 1 to 3 substituents chosen from C 1-6 alkyl and C 1-6 alkoxy; each R 4 or R 4 substituent where possible is optionally partially or fully halogenated; n is 1; or a pharmaceutically acceptable salt thereof.