Patent ID: 7691825

Claim:
A compound of the formula wherein R 1 is an optionally substituted aryl or heteroaryl; n is zero or 1; R 2 is H or halogen; R 3 is CH 2 OR 4 in which R 4 is H or C 1 -C 6 alkyl provided that R 4 is not H when n is zero and R 1 is unsubstituted phenyl; or R 3 is C(O)NH—R 5 in which R 5 is C 1 -C 6 alkyl; or R 3 is in which R 6 , R 7 , and R 8 are H or C 1 -C 6 alkyl; or a pharmaceutically acceptable salt thereof; and wherein optionally substituted aryl refers to an unsaturated aromatic carbocyclic group of from 6 to 14 carbon atoms having a single ring or multiple condensed rings which may be optionally substituted with from 1 to 3 substituents selected from the group consisting of hydroxy, acyl, alkyl, alkoxy, alkylthio, alkenyl, alkynyl, amino, acyloxy, acylamino, aryl, aralkyl, aryloxy, azido, carboxy, cyano, halo, nitro, heteroaryl, heteroaryloxy, trihalomethoxy, dihalomethyl, trihalomethyl and perhaloalkyl; and optionally substituted heteroaryl refers to an unsaturated aromatic heterocyclic group having a single ring or multiple condensed rings, from 1 to 15 carbon atoms and from 1 to 4 hetero atoms selected from the group consisting of nitrogen, sulfur and oxygen within the ring, and which may be optionally substituted with from 1 to 3 substituents selected from the group consisting of hydroxy, acyl, alkyl, alkoxy, alkylthio alkenyl, alkynyl, amino, acyloxy, acylamino, aralkyl, aryloxy, azido, carboxy, cyano, halo, nitro, heteroaryl, heteroaryloxy, trihalomethoxy, dihalomethyl, perhaloalkyl and trihalomethyl.