Patent ID: 7618982

Claim:
A compound represented by formula (I) wherein A is selected from the group consisting of pyridin-4-yl, 3-fluoro-pyridin-4-yl, and 2-amino-pyrimidin-4-yl; R 1 is selected from the group consisting of hydrogen, halogen and (C 1 -C 6 )alkyl; R 2 is selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 3 -C 6 )cycloalkyl, (C 1 -C 6 )haloalkyl, (C 1 -C 6 )polyfluorinated alkyl, heterocyclyl, aryl, heteroaryl, (C 3 -C 6 )cycloalkyl-(C 1 -C 6 )alkyl, heterocyclyl-(C 1 -C 6 )alkyl, aryl-(C 1 -C 6 )alkyl, heteroaryl-(C 1 -C 6 )alkyl, (C 1 -C 8 )hydroxyalkyl, (C 1 -C 8 )alkoxy-(C 1 -C 8 )alkyl, aryloxy-(C 1 -C 8 )alkyl, heteroaryloxy-(C 1 -C 8 )alkyl, (C 1 -C 8 )aminoalkyl, (C 1 -C 8 )alkylamino-(C 1 -C 8 )alkyl, (C 1 -C 8 )dialkylamino-(C 1 -C 8 )alkyl, carbamoyl-(C 1 -C 8 )alkyl, and alkoxycarbonyl, wherein each of said aryl, heteroaryl, heterocyclyl, aryloxy, and heteroaryloxy moieties can be unsubstituted or substituted by one or more substituents, each substituent being independently selected from the group consisting of alkyl, aryl, —OCF 3 , —OC(O)alkyl, —OC(O)aryl, —CF 3 , heteroaryl, aralkyl, alkylaryl, heteroaralkyl, alkylheteroaryl, hydroxy, hydroxyalkyl, alkoxy, aryloxy, aralkoxy, acyl, aryl, halo, haloalkyl, haloalkoxy, nitro, cyano, carboxy, alkoxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl, alkylsulfonyl, arylsulfonyl, heteroarylsulfonyl, alkylsulfinyl, arylsulfinyl, heteroarylsulfinyl, alkylthio, arylthio, heteroarylthio, aralkylthio, heteroaralkylthio, cycloalkyl, heterocyclyl, heterocyclenyl, —NH(alkyl), —NH(cycloalkyl), and —N(alkyl) 2 ; R 3 , R 4 , R 5 and R 6 are each independently selected from the group consisting of hydrogen, (C 1 -C 6 )haloalkyl, (C 1 -C 6 )polyfluorinated alkyl, (C 1 -C 6 )haloalkenyl, (C 1 -C 6 )polyfluroinated alkenyl, (C 1 -C 8 )hydroxyalkyl, (C 1 -C 8 )alkoxy-(C 1 -C 8 )alkyl, aryloxy-(C 1 -C 8 )alkyl, heteroaryloxy-(C 1 -C 8 )alkyl, aryl-(C 1 -C 8 )alkoxy-(C 1 -C 8 )alkyl, (C 1 -C 8 )azidoalkyl group, (C 1 -C 8 )aminoalkyl, (C 1 -C 8 )alkylamino-(C 1 -C 8 )alkyl, (C 1 -C 8 )dialkylamino-(C 1 -C 8 )alkyl, and (C 1 -C 8 )alkyl-OC(O)-amino(C 1 -C 8 )alkyl, with the proviso that at least one of: R 3 , R 4 , R 5 or R 6 is different from hydrogen; or a pharmaceutically acceptable salt or solvate thereof.