Patent ID: 8007995

Claim:
A method for determining the responsiveness of a mammalian breast tumor cell to treatment with N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide or a pharmaceutically acceptable salt, solvate, or hydrate thereof, the method comprising determining the level of expression of yes-associated protein 1 in a biological sample comprising a breast tumor cell; and correlating a finding of elevated expression of yes-associated protein 1, as compared to the level of expression of a control, with said breast tumor cell being sensitive to said treatment with N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide or a pharmaceutically acceptable salt, solvate, or hydrate thereof.