Patent ID: 7550482

Claim:
A compound selected from those of Formula I wherein R 1 represents aryl or heteroaryl; R 2 and R 3 , which may be the same or different, represent hydrogen or C 1-6 alkyl; R 4 and R 5 , which may be the same or different, represent hydrogen or C 1-6 alkyl; it being understood that: aryl represents an unsubstituted phenyl ring or a phenyl ring that is substituted with 1, 2, 3, 4 or 5 substituents, that may be the same or different, which substituents are selected from C 1-6 alkyl, which is optionally substituted with one or more fluorine, chlorine or bromine atoms, C 1-6 alkoxy, which is optionally substituted with one or more fluorine, chlorine or bromine atoms, cycloC 3-12 alkyl, hydroxyl, F, Cl, Br, I, CN, nitro, di-C 1-6 alkylamino, N-cycloC 3-12 alkyl-N-C 1-6 alkylamino, azetidinyl, pyrrolidinyl, piperidinyl, morpholinyl, 4-C 1-6 alkyl-piperazinyl, tetrazolyl, oxazolyl, furyl, thiophenyl, pyrrolyl, isoxazolyl, thiazolyl, imidazolyl, oxadiazolyl, pyridinyl, pyrimidyl, and phenyl; heteroaryl represents a (hetero)aromatic 5-, 6- or 7-membered ring having from 1 to 4 heteroatoms, said heteroatoms being independently selected from oxygen, nitrogen and sulfur, wherein said ring is unsubstituted or substituted with 1, 2 or 3 substituents, that may be the same or different, which substituents are selected from C 1-6 alkyl, which is optionally substituted with one or more fluorine, chlorine or bromine atoms, C 1-6 alkoxy, which is optionally substituted with one or more fluorine, chlorine or bromine atoms, cycloC 3-12 alkyl, hydroxyl, F, Cl, Br, I, CN, nitro, di-C 1-6 alkylamino, N-cycloC 3-12 alkyl-N—C 1-6 alkylamino, azetidinyl, pyrrolidinyl, piperidinyl, morpholinyl, 4-C 1-6 alkyl-piperazinyl, tetrazolyl, oxazolyl, furyl, thiophenyl, pyrrolyl, isoxazolyl, thiazolyl, imidazolyl, oxadiazolyl, pyridinyl, pyrimidyl, and phenyl; and optical isomers and pharmaceutically acceptable salts thereof.