Patent ID: 7541330

Claim:
A conjugate having a structure according to one of formulae X, XI, or XII: wherein AA 1 is a lysine, arginine, or citrulline amino acid side chain residue; AA 2 is a phenylalanine, valine, alanine, leucine, or isoleucine amino acid side chain residue; p in formulae X to XII is an integer from 1 to 6; q in formulae X to XII is an integer from 1 to 5; r in formulae X to XII is an integer from 1 to 5; —C(═O)LMB in formulae X to XII is a leptomycin B residue, having the structure x ⊖ in formulae X to XII is a pharmaceutically acceptable counteranion; and mAb is a monoclonal antibody.