Patent ID: 8148385

Claim:
A compound of Formula (I): wherein: R 1 is selected from hydrogen, hydroxy-C 1-8 alkyl, C 1-8 alkoxy-C 1-8 alkyl or carboxy-C 1-8 alkyl; R 2 is selected from C 1-8 alkyl, C 1-8 alkoxy-C 1-8 alkyl, C 1-8 alkyl-thio-C 1-8 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-8 alkyl, phenyl-C 1-8 alkyl, heterocyclyl, heterocyclyl-C 1-8 alkyl, heteroaryl-C 1-8 alkyl or halo-C 1-8 alkyl, wherein each instance of C 3-8 cycloalkyl, heterocyclyl and heteroaryl is optionally substituted with C 1-8 alkyl, phenyl or benzyl, wherein phenyl is optionally substituted with C 1-4 alkyl, C 1-4 alkoxy, amino, C 1-4 alkyl-amino, hydroxy, cyano, halo-C 1-4 alkyl or halogen; R 3 and R 4 are each selected from hydrogen or are optionally taken together with the carbon atoms of attachment to form a heterocyclyl ring having 5 or 6 ring members, wherein said heterocyclyl ring is optionally substituted with one or two C 1-8 alkyl substituents; and, X 1 and X 2 are each selected from CH, CH 2 or CH(OH), wherein when either X 1 or X 2 is CH, then X 1 and X 2 must both be CH and the dashed line represents a double bond, and enantiomers, stereoisomers, and pharmaceutically acceptable salts thereof.