Patent ID: 7541033

Claim:
An antibody, or an antigen-binding portion thereof, that specifically binds human IL-1β, comprising a light chain variable region and a heavy chain variable region selected from the group consisting of: (a) a light chain variable region encoded by the polynucleotide sequence of SEQ ID NO:60 and a heavy chain variable region encoded by the polynucleotide sequence of SEQ ID NO:55; (b) a light chain variable region encoded by the polynucleotide sequence of SEQ ID NO:61 and a heavy chain variable region encoded by the polynucleotide sequence of SEQ ID NO:56; (c) a light chain variable region encoded by the polynucleotide sequence of SEQ ID NO:62 and a heavy chain variable region encoded by the polynucleotide sequence of SEQ ID NO:57; (d) a light chain variable region encoded by the polynucleotide sequence of SEQ ID NO:63 and a heavy chain variable region encoded by the polynucleotide sequence of SEQ ID NO:58; and, (e) a light chain variable region encoded by the polynucleotide sequence of SEQ ID NO:64 and a heavy chain variable region encoded by the polynucleotide sequence of SEQ ID NO:59.