Patent ID: 7846945

Claim:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: A is optionally substituted aryl, cycloalkyl, or heterocycle; B is optionally substituted aryl, cycloalkyl, or heterocycle; Y is O, S, SO, SO 2 , NR 4 , (C(R 5 ) 2 ) p , (C(R 5 ) 2 ) q —C(O)—(C(R 5 ) 2 ) q , (C(R 5 ) 2 ) q —C(O)O—(C(R 5 ) 2 ) q , (C(R 5 ) 2 ) q —OC(O)—(C(R 5 ) 2 ) q , (C(R 5 ) 2 ) q —C(O)NR 4 —(C(R 5 ) 2 ) q , (C(R 5 ) 2 ) q —NR 4 C(O)—(C(R 5 ) 2 ) q , or (C(R 5 ) 2 ) q —NR 4 C(O)NR 4 —(C(R 5 ) 2 ) q ; R 1 is OR 1A , SR 1A , SOR 1A , SO 2 R 1A , or R 1A ; each R 1A is independently hydrogen or optionally substituted alkyl, aryl or heterocycle; R 2 is fluoro or OR 2A ; each of R 2A , R 2B , and R 2C is independently hydrogen, optionally substituted alkyl, C(O)alkyl, C(O)aryl, or aryl; R 3 is hydrogen or optionally substituted alkyl, aryl or heterocycle; each R 4 is independently hydrogen or optionally substituted alkyl; each R 5 is independently hydrogen, hydroxyl, halogen, amino, cyano, OR 5A , SR 5A , or optionally substituted alkyl; each R 5A is independently optionally substituted alkyl; each R 6 is independently hydrogen, hydroxyl, halogen, amino, cyano, nitro, C═CR 6A , OR 6A , SR 6A , SOR 6A , SO 2 R 6A , C(O)R 6A , CO 2 R 6A , CO 2 H, CON(R 6A )(R 6A ), CONH(R 6A ), CONH 2 , NHC(O)R 6A , NHSO 2 R 6A , or optionally substituted alkyl, aryl or heterocycle; each R 6A is independently optionally substituted alkyl, aryl or heterocycle; each R 7 is independently hydrogen, hydroxyl, halogen, amino, cyano, nitro, C≡CR 7A , OR 7A , SR 7A , SOR 7A , SO 2 R 7A , C(O)R 7A , CO 2 R 7A , CO 2 H, CON(R 7A )(R 7A ), CONH(R 7A ), CONH 2 , NHC(O)R 7A , NHSO 2 R 7A , or optionally substituted alkyl, aryl or heterocycle; each R 7A is independently optionally substituted alkyl, aryl or heterocycle; m is 1-3; n is 1-3; p is 0-3; and each q is independently 0-2; with the proviso that at least one of R 6 and R 7 is not hydrogen.