Patent ID: 7816328

Claim:
A method for treating diabetes or Syndrome X, or associated symptoms or complications thereof in a subject, comprising (a) administering to said subject a jointly effective amount of a compound of formula IV: wherein: one of the dashed lines between NR 1 and X or between X and Y is present and represents a double bond, or both are absent; two of V, M, and W are H and the third is R 1 is C 1-4 alkyl; or, where the dashed line between NR 1 and X is present, R 1 is absent; X is N, C═O, CH, or C-Q-Z; Y is N-Q-Z or C-Q-Z, where X is N, C═O, or CH; Y is CH, where X is C-Q-Z; Q=—(CH 2 ) n — where n=1 or 2; P=H, C 1-7 acyl, or C 1-6 alkoxycarbonyl; Z is substituted or unsubstituted, and is selected from C 3-7 cycloalkyl, phenyl, a 5- or 6-membered heteroaryl having 1 or 2 heteroatoms independently selected from N, O, and S, a biaryl, a 9- or 10-membered fused bicyclyl, and a fused heterobicyclyl, wherein said fused heterobicyclyl has between 1 and 4 heteroatoms independently selected from N, O, and S; or a pharmaceutically acceptable salt, thereof; (b) administering to said subject a jointly effective amount of a second antidiabetic agent, and (c) administering to said subject a jointly effective amount of a third antidiabetic agent.