Patent ID: 7294640

Claim:
A compound according to Formula I: is phenyl; X is: C(R 4 ) 2 4 ; a is independently 0 or 1; b is independently 0 or 1; m is independently 0, 1 or 2; n is independently 0, 1, 2, 3 or 4; R 1 and R 2 are independently selected from: H, CF 3 , oxo, OH, halo, CN, NH 2 , NO 2 , (C═O) a O b (C 1 -C 10 )alkyl, (C═O) a O b (C 2 -C 10 )alkenyl, (C═O) a O b (C 2 -C 10 )alkynyl, (C═O) a O b (C 3 -C 6 )cycloalkyl, (C═O) a O b (C 0 -C 6 )alkylene-aryl, (C═O) a O b (C 0 -C 6 )alkylene-N(R b ) 2 , O b (C 1 -C 3 )perfluoroalkyl, (C 0 -C 6 )alkylene-S(O) m R a , C(O)R a , (C 0 C 6 )alkylene-CO 2 R a , C(O)H, (C 0 -C 6 )alkylene-CO 2 H, C(O)N(R b ) 2 , and S(O) 2 N(R b ) 2 ; said alkyl, alkenyl, alkynyl, cycloalkyl, aryl, and alkylene is optionally substituted with up to three substituents selected from R b , OH, (C 1 -C 6 )alkoxy, halogen, CO 2 H, CN, (O)C═O(C 1 -C 6 )alkyl, oxo, and N(R b ) 2 ; R 3 is selected from: (C 1 -C 6 )alkyl, amino(C 1 -C 6 )alkyl, (C 1 -C 6 )alkyl amino, hydroxy (C 1 -C 6 )alkyl, OH and NH 2 ; two R 4 s are combined to form an alkylene diradical selected from: —CH 2 CH 2 —, —CH 2 CH 2 CH 2 —and —CH 2 CH 2 CH 2 CH 2 —; R a is selected from: (C 1 -C 6 )alkyl, (C 3 -C 6 )cycloalkyl, and aryl; said alkyl, cycloalkyl, and aryl is optionally substituted with one or more substituents selected from R 3 ; R b is independently selected from: H, oxo, OH, (C 1 -C 6 )alkyl, aryl, (C 3 -C 6 )cycloalkyl, (C═O)O(C 1 -C 6 )alkyl, C═O(C 1 -C 6 )alkyl and S(O) 2 R a ; said alkyl, cycloalkyl, or aryl is optionally substituted with one or more substituents selected from R 3 ; or a pharmaceutically acceptable salt or stereoisomer thereof.