Patent ID: 7872106

Claim:
An isolated antibody or fragment thereof that binds sclerostin of SEQ ID NO: 1 with a dissociation constant of less than or equal to 1×10 −7 M, comprising six CDRs, CDR-H1, CDR-H2, CDR-H3, CDR-L1, CDR-L2 and CDR-L3, wherein CDR-H1 has the sequence given in SEQ ID NO: 269, CDR-H2 has the sequence given in SEQ ID NO: 270, CDR-H3 has the sequence given in SEQ ID NO: 271, CDR-L1 has the sequence given in SEQ ID NO: 239, CDR-L2 has the sequence given in SEQ ID NO: 240 and CDR-L3 has the sequence given in SEQ ID NO: 241.