Patent ID: 7045503

Claim:
A method of treating a tumor, comprising administering to a human patient a radiolabeled peptide and a pharmaceutically acceptable carrier, wherein said peptide comprises a radiometal-binding moiety comprising the structure: wherein R 1 , R 2 , and R 3 independently are selected from the group consisting of H, C 1 –C 6 alkyl, substituted C 1 –C 6 alkyl, C 3 –C 6 cycloalkyl, substituted C 3 –C 6 cycloalkyl, heterocycloalkyl, C 6 –C 12 aryl, C 6 –C 12 substituted aryl, heteroaryl, substituted heteroaryl, alkaryl, and a protecting group, provided that at least one of R 1 , R 2 , or R 3 is H, R 5 , R 7 , R 8 , R 9 and R 10 independently are selected from the group consisting of H, C 1 –C 6 alkyl, substituted C 1 –C 6 alkyl, C 6 –C 12 aryl, and substituted C 6 –C 12 aryl, and R 8 and R 9 together or R 7 and R 9 together may form a cycloalkyl or substituted cycloalkyl ring, R 4 and R 6 together form a direct bond or are independently selected from the group consisting of C 1 –C 6 alkyl, substituted C 1 –C 6 alkyl, C 6 –C 12 aryl, and substituted C 6 –C 12 aryl, and wherein NR 10 is located at the N-terminus of said peptide, or is located on an amino acid side chain of said peptide.