Patent ID: 8032198

Claim:
An apparatus for detecting an analyte in tissue of a subject comprising: an elongated conductive material having a protrudent end, the protrudent end comprising a sensor that detects the presence of an analyte, wherein the sensor comprises a plurality of layers including: a base layer; a plurality of electrodes disposed on the base layer including a working electrode, a counter electrode and a reference electrode; an analyte sensing layer comprising glucose oxidase disposed upon the working electrode; and an analyte modulating layer disposed on the glucose oxidase layer; a support comprising an intravenous infusion catheter having a lumen and having an external surface, a proximal end, and a distal end; wherein the conductive material is positioned on the support and the protrudent end of the conductive material comprising the sensor that detects the presence of an analyte: (a) protrudes beyond the distal end of the support; and (b) is positioned on the external surface of the intravenous infusion catheter in combination with a venous flow device and assembly means, wherein the sensor is affixed to the sensor end of the assembly means and the assembly means is adapted for coupling with the venous flow device.