Patent ID: 7713996

Claim:
A compound of formula (I): wherein X is N or CR 8 ; Y is N or CR 9 ; A is —C(R 10 R 11 )C(R 12 R 13 )—, —C(R 10 R 11 )C(R 12 R 13 )C(R 14 R 15 )—, —C(R 10 R 11 )C(R 12 R 13 )C(R 14 R 15 )C(R 16 R 17 )—, —C(R 10 R 11 )C(R 12 R 13 )C(R 14 R 15 )C(R 16 R 17 )C(R 18 R 19 )— or —C(R 10 )═C(R 11 )—; R 1 , R 2 , R 3 , R 4 and R 5 independently from each other are hydrogen, halogen, cyano, hydroxy, lower-alkyl, fluoro-lower-alkyl, lower-alkoxy, fluoro-lower-alkoxy, lower-alkyl-C(O), lower-alkyl-C(O)—NH, lower-alkyl-C(O)—N(lower-alkyl), lower-alkyl-S(O) 2 , NH 2 —S(O) 2 , N(H, lower-alkyl)-S(O) 2 or N(lower-alkyl) 2 -S(O) 2 , NH 2 —C(O), N(H, lower-alkyl)-C(O), N(lower-alkyl) 2 -C(O) or lower-alkoxy-C(O), wherein lower-alkyl is optionally substituted with hydroxy, lower-alkoxy, NH 2 , N(H, lower-alkyl) or N(lower-alkyl) 2 ; R 6 is hydrogen, halogen, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl, fluoro-lower-alkoxy, hydroxy or hydroxy-lower-alkyl; R 7 is hydrogen, halogen, hydroxy, cyano, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl, fluoro-lower-alkoxy or hydroxy-lower-alkyl; R 8 is hydrogen, halogen, cyano, lower-alkyl, fluoro-lower-alkyl, lower-alkoxy, fluoro-lower-alkoxy, lower-alkyl-C(O), lower-alkyl-C(O)—NH, lower-alkyl-C(O)—N(lower-alkyl), lower-alkyl-S(O) 2 , NH 2 —S(O) 2 , N(H, lower-alkyl)-S(O) 2 , N(lower-alkyl) 2 -S(O) 2 , NH 2 —C(O), N(H, lower-alkyl)-C(O), N(lower-alkyl) 2 -C(O), lower-alkoxy-C(O), COOH, 1H-tetrazolyl, 4H-[1,2,4]oxadiazol-3-yl-5-one, 4H-[1,2,4]thiadiazol-3-yl-5-one, 4H-[1,2,4]oxadiazol-3-yl-5-thione, 3H-[1,2,3,5]oxathiadiazol-4-yl-2-oxide, SO 3 H, 3-hydroxy-isooxazolyl, 3-hydroxy-pyran-4-one-yl or P(O)(OCH 2 CH 3 )OH, wherein lower-alkyl is optionally substituted with hydroxy, NH 2 , N(H, lower-alkyl) or N(lower-alkyl) 2 , and wherein fluoro-lower-alkyl is optionally substituted with hydroxy; R 9 is hydrogen, halogen, hydroxy, cyano, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl, fluoro-lower-alkoxy or hydroxy-lower-alkyl; R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 independently from each other are hydrogen, halogen, hydroxy, lower-alkyl, lower-alkoxy, fluoro-lower-alkyl, fluoro-lower-alkoxy, hydroxy-lower-alkyl or cyano; and pharmaceutically acceptable salts and esters thereof.