Patent ID: 7538246

Claim:
A process for making (R)-5-(2-aminopropyl) -2-methoxybenzene sulphonamide comprising the following steps: a) protection of the amino group of D-alanine, b) reaction of the N-protected D-alanine with methoxybenzene to make 4′-methoxy-2-amino protected propiophenone, c) reduction of the oxo-group of the 4′-methoxy-2-amino protected propiophenone to make amino-protected 1-(4-methoxyphenyl)propane-2-amine, d) chlorosulphonation of the amino-protected 1-(4-methoxyphenyl)propane-2-amine and ammonolysis of the chlorosulphonyl group, and e) deprotecton of the amino group.