Patent ID: 7504509

Claim:
A compound having the chemical structure of Formula I, or a pharmaceutically acceptable salt thereof, where, with reference to Formula I: R 1 and R 5 are hydrogen; R 2 is —CH 2 -(optionally substituted aryl), —CH 2 -(optionally substituted heteroaryl), —C(O)R 20 , or —S(O) n R 21 ; one of R 3 and R 4 is hydrogen and the other of R 3 and R 4 is halo, hydroxy, optionally substituted alkoxyl, optionally substituted thioalkoxy, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, —C(X)R 20 , C(X)NR 16 R 17 , S(O) 2 NR 16 R 17 , —NR 22 R 23 , or —S(O) n R 21 ; R 16 and R 17 are independently hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, or optionally substituted heteroaralkyl, or R 16 and R 17 together form a 5-7 membered carbocyclic or heterocyclic ring; R 20 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, or optionally substituted heteroaralkyl; R 21 is substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, or optionally substituted heteroaralkyl; R 22 and R 23 are independently hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, optionally substituted heteroaralkyl, —C(X)R 20 , C(X)NR 16 R 17 , or —S(O) 2 R 21 ; X=O or S; and n=0, 1, or 2.