Patent ID: 8575180

Claim:
An 8-oxoadenine compound shown by the formula (1): wherein ring A represents a 6-10 membered aromatic carbocyclic ring or a 5-10 membered heteroaromatic ring; R represents a halogen atom, an alkyl group, a hydroxyalkyl group, a haloalkyl group, an alkoxy group, a hydroxyalkoxy group, a haloalkoxy group, amino group, an alkylamino group, a dialkylamino group, or a 4-7 membered cyclic group containing in the ring 1-2 hetero atoms selected from 1-2 nitrogen atoms and optionally 0-1 oxygen atom or 0-1 sulfur atom; n represents an integer of 0-2, and when n is 2, the Rs may be the same or different; Z 1 represents a substituted or unsubstituted alkylene group or a substituted or unsubstituted cycloalkylene group; X 2 represents oxygen atom, sulfur atom, SO 2 , NR 5 , CO, CONR 5 , NR 5 CO, SO 2 NR 5 , NR 5 SO 2 , NR 5 CONR 6 or NR 5 CSNR 6 (in which R 5 and R 6 are each independently hydrogen atom, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted cycloalkyl group); Y 1 , Y 2 and Y 3 represent each independently a single bond or an alkylene group; X 1 represents oxygen atom, sulfur atom, SO 2 , NR 4 (wherein R 4 is hydrogen atom or an alkyl group) or a single bond; R 2 represents hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group or a substituted or unsubstituted cycloalkyl group; and R 1 represents hydrogen atom, hydroxy group, an alkoxy group, an alkoxycarbonyl group, a haloalkyl group, a haloalkoxy group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group or a substituted or unsubstituted cycloalkyl group, or its pharmaceutically acceptable salt.