Patent ID: 7598353

Claim:
A fusion molecule comprising: a first portion that targets cells bearing the OX-2/CD200 antigen, wherein the first portion is an anti-CD200 antibody or antigen binding fragment thereof that binds to CD200 comprising: (i) a light chain CDR1 having the sequence set forth in residues 26-36 of SEQ ID NO: 209, (ii) a light chain CDR2 having the sequence set forth in residues 52-58 of SEQ ID NO: 209, (iii) a light chain CDR3 having the sequence set forth in residues 91-99 of SEQ ID NO: 209, (iv) a heavy chain CDR1 having the sequence set forth in SEQ ID NO: 149, (v) a heavy chain CDR2 having the sequence set forth in SEQ ID NO: 174, and (vi) a heavy chain CDR3 having the sequence set forth in SEQ ID NO: 195; and a second portion that is a toxin.