Patent ID: 8088760

Claim:
A compound of Formula (I) or Formula (II): wherein: Y is selected from the group consisting of a) an aryl group optionally substituted with 1, 2, or 3 R 5 ; wherein each R 5 is selected independently from the group consisting of alkenyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, alkyl, alkynyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, cyano, haloalkoxy, haloalkyl, halogen, hydroxyl, hydroxyalkyl, nitro, oxo, heteroaryl, heteroarylalkyl, heteroarylalkoxy, heteroaryloxy, heteroarylthio, heteroarylalkylthio, heterocycle, heterocycloalkoxy, heterocycloalkylthio, heterocyclooxy, heterocyclothio, NR A R B , (NR A R B )alkyl, (NR A R B )carbonyl, (NR A R B )carbonylalkyl, and (NR A R B )sulfonyl, wherein when Y is phenyl, the phenyl is substituted with at least one substituent selected independently from the group consisting of alkoxyalkyl, heteroaryl, heteroarylalkoxy, heteroaryloxy, heteroarylthio, heteroarylalkylthio, heterocycle, heterocycloalkoxy, heterocycloalkylthio, heterocyclooxy, heterocyclothio, and (NR A R B )alkyl; b) a heteroaryl group optionally substituted with 1, 2, or 3 R 5 ; wherein each R 5 is as previously defined; c) a L-T group where L is selected from the group consisting of alkenylene, alkylene, alkynylene, cycloalkylene and spiroheterocycle and T is selected from the group consisting of heteroaryl, heteroarylalkoxy, heteroaryloxy, heteroarylthio, heteroarylalkylthio, heterocycle, heterocycloalkoxy, heterocycloalkylthio, heterocyclooxy, heterocyclothio, and NR A R B ; d) a non-aromatic 4, 5, 6, 7, 8, 9, 10, 11, or 12-membered monocyclic or bicyclic heterocycle ring having 1 or 2 nitrogen atoms and, optionally, one sulfur or oxygen atom, wherein the heterocycle is optionally substituted with 1, 2, or 3 R 6 ; wherein each R 6 is selected independently from the group consisting of alkenyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, alkyl, alkynyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, cyano, haloalkoxy, haloalkyl, halogen, hydroxyl, hydroxyalkyl, nitro, oxo, heteroaryl, heteroarylalkyl, heteroarylalkoxy, heteroaryloxy, heteroarylthio, heteroarylalkylthio, heterocycle, heterocycloalkoxy, heterocycloalkylthio, heterocyclooxy, heterocyclothio, NR A R B , (NR A R B )alkyl, (NR A R B )carbonyl, (NR A R B )carbonylalkyl, and (NR A R B )sulfonyl and wherein when the heterocycle is bicyclic, the optional substituent(s) are attached to either one or both of the cyclic rings; R 1 , R 2 , and R 3 , are each independently selected from the group consisting of hydrogen, halogen, alkenyl, alkoxy, alkoxycarbonyl, alkyl, cycloalkyl, alkynyl, cyano, haloalkoxy, haloalkyl, hydroxyl, hydroxyalkyl, nitro, NR C R D , and (NR C R D )carbonyl; each R A , R B , R C , and R D is independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, and alkylcarbonyl; R 4 , is selected from the group consisting of hydrogen, alkyl, cycloalkyl, alkoxyalkyl, haloalkyl, hydroxyalkyl, and (NR A R B )alkyl; or stereoisomers, and salts thereof.