Patent ID: 7074905

Claim:
An empty MHC complex comprising an sc-MHC class II molecule comprising linked in sequence an MHC Î² chain-peptide linker-MHC Î± chain, the MHC complex having the general formula: wherein, a) A represents at least one empty sc-MHC class II molecule, b) B1, B2 are each independently a joining molecule, c) C1, C2 are each independently an effector molecule or â€”H, wherein the effector molecules are each selected from the group consisting of a cell toxin other than ricin or diphtheria toxin, a chemotherapeutic drug, a radionuclide, a protein tag, a hormone, a fluor, an enzyme, an enzyme substrate, a cofactor, an enzyme inhibitor, a ligand, a hapten, biotin, a carbohydrate, and a fatty acid, and d) D represents at least one ligand binding molecule or â€”H.