Patent ID: 6995177

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof: wherein: represents a benzene ring or a non-aromatic carbocyclic ring and (n) is the total number of carbon atoms in the carbocyclic ring and is from 4 to 8; A is (i) cyclohexylmethyl- or (ii) phenyl optionally substituted with from 1 to 3 substituents independently selected from halo, C 1-4 alkyl, C 1-4 fluoroalkyl, —O—C 1-4 alkyl, O—C 1-4 fluoroalkyl, and R a —C(═O)O—, where R a is naphthylmethyl-, 2,2-diphenylmethyl-, or carboxycyclohexyl-; B is hydrogen, lower alkyl of 1–6 carbon atoms or is an aralkyl group containing from 7 to 18 carbon atoms in which the aryl group is optionally substituted with one or more substituents independently selected from halo, C 1-4 alkyl, C 1-4 fluoroalkyl, —O—C 1-4 alkyl, —O—C 1-4 fluoroalkyl; D is hydrogen, or a group of formula: where Y is hydrogen, an alkyl group containing 1 to 6 carbon atoms, or a cycloalkyl group containing 3 to 8 carbon atoms; each of the stereocenters a and b is independently in the R configuration or the S configuration; p is 1 or 2; and X is selected from hydroxyl, and —O—C 1-6 alkyl groups; provided that if B is hydrogen or lower alkyl, D is not also hydrogen, and if D is hydrogen B is an aralkyl group.