Patent ID: 8921397

Claim:
A compound of formula (I) wherein n is 0, 1, 2, 3 or 4; Y is —C(O)— or —S(O) 2 —; R 1 is hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl, adamantyl, heterocycloalkyl, aryl, aryl anellated to heterocycloalkyl, heteroaryl, —NR 6 R 7 , hydroxy, alkoxy, or haloalkoxy; wherein alkyl, alkenyl, alkynyl, haloalkyl, alkoxy and haloalkoxy are each optionally substituted by one, two or three independent R 4 ; and wherein cycloalkyl, adamantyl, heterocycloalkyl, aryl, aryl anellated to heterocycloalkyl, and heteroaryl are each optionally substituted by one, two or three independent R 5 ; R 2 and R 3 are each hydrogen; R 4 is cyano, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, —C(O)NR 6 R 7 , —NR 6 R 7 , —NH(CO)-alkyl, hydroxy, alkoxy, haloalkoxy, oxo, or —S(O) 2 R 6 ; wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, are each optionally substituted by one, two or three independent R 5 ; R 5 is halogen, cyano, alkyl, haloalkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, —C(O)NR 6 R 7 , —NR 6 R 7 , —NH(CO)-alkyl, hydroxy, alkoxy, haloalkoxy, oxo, or —S(O) 2 R 6 ; wherein cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, are each optionally substituted by one, two or three substituents independently selected from halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, and oxo; R 6 and R 7 are each independently hydrogen, alkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heterocycloalkylalkyl, aryl, or heteroaryl; or a pharmaceutically acceptable salt or ester thereof.