Patent ID: 8071640

Claim:
A method for treating bacterial or fungal diseases in a subject in need of such treatment comprising administering to said subject an effective amount of a compound of formula: X-(A) n -Y,â€ƒâ€ƒ(I) in which: n varies from 6 to 20, X is selected from the group consisting of hydrogen, R a CO, R a OCO, R a NHCO, R a SO 2 and R a NHCS, R a is selected from the group consisting of fluorescein, (C1-C10 alkyl), (C1-C10) alkenyl, (C1-C10) alkynyl, (C5-C12) aryl, (C5-C14) aralkyl, and (C1-C5) heteroaryl, which groups are unsubstituted or substituted by 1 to 6 substituents selected from the group consisting of: halogen, NO 2 , OH, (C1-C4) alkyl, NH 2 , CN, trihalomethyl, (C1-C4) acyloxy, (C1-C4) dialkylamino, guanidino, SH, and maleimide, provided that X is not H when n is 6, A represents either: R being selected from the group consisting of hydrogen, an amino acid side chain, (C1-C10) alkyl, (C1-C10) alkenyl, (C1-C10) alkynyl, (C5-C12) aryl, (C5-C14) aralkyl and (C1-C10) heteroaryl, said groups being unsubstituted or substituted by 1 to 6 substituents selected from the group consisting of: halogen, NO 2 , OH, amidine, benzamidine, imidazole, alkoxy, (C1-C4) alkyl, NH 2 , CN, trihalomethyl, acyloxy (C1-C4), dialkylamino (C1-C4), and guanidino, and with the proviso that approximately 10% to approximately 50% of the R substituents are amino acid side chains of basic character, Y is an NR b R c group, R b and R c having the same meaning as for R, provided that the compounds of the following formulae are excluded: