Patent ID: 8507473

Claim:
A compound selected from compounds of Formula (Ia) and pharmaceutically acceptable salts, solvates and hydrates thereof: wherein: R 1 is aryl, heteroaryl, C 3 -C 10 cycloalkyl, or heterocyclyl, each optionally substituted with 1, 2, or 3 substitutents independently selected from the group consisting of C 1 -C 6 alkoxy, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkyl, C 1 -C 6 alkylthio, aryl, C 3 -C 6 cycloalkyl, halogen, C 1 -C 6 haloalkoxy, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkylthio, hydroxyl, nitro, and oxo, wherein C 1 -C 6 alkyl is optionally substituted with aryl; or two adjacent substitutents together with the atoms to which they are both bonded form a five-membered cycloalkyl or a five-membered heterocyclyl; and R 2 is H, C 1 -C 6 alkyl, C 1 -C 6 alkylthio, amino, aryl, C 3 -C 6 cycloalkyl, or halogen.