Patent ID: 8183250

Claim:
A compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of hydrogen, alkenyl, alkoxy, alkoxycarbonyl, alkyl, alkynyl, cyano, haloalkoxy, haloalkyl, halogen, hydroxy, hydroxyalkyl, nitro, NR A R B , and (NR A R B )carbonyl; X is heterocyclealkyl, wherein X is unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents, Z, independently selected from the group consisting of alkyl, alkenyl, alkynyl, nitro, —CN, halogen, haloalkyl, alkoxy, alkylcarbonyl, alkylcarbonylalkyl, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, aryl, arylalkyl, arylalkoxy, arylalkoxycarbonyl, arylalkylcarbonyl, carboxy, carboxyalkyl, cycloalkyl, cycloalkylalkyl, cycloalkylalkoxy, cycloalkylcarbonyl, heteroaryl, heteroarylalkyl, heteroarylcarbonyl, heteroarylcarbonylalkyl, heterocycle, heterocyclealkyl, heterocyclealkylcarbonyl, heterocyclecarbonyl, heterocyclecarbonylalkyl, hydroxy, hydroxyalkyl, NR C R D , (NR C R D )alkyl, (NR C R D )carbonyl, (NR C R D )carbonylalkyl, and oxo; wherein the aryl and the heteroaryl moieties of Z are independently unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents selected from the group consisting of alkyl, formyl, halogen, and haloalkyl, and the heterocycle and cycloalkyl moieties of Z are independently unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents selected from the group consisting of alkyl, oxo, formyl, halogen, and haloalkyl; R C and R D are independently selected from the group consisting of hydrogen, alkyl, alkylcarbonyl, alkylcarbonyloxyalkylcarbonyl, arylcarbonyl, aryl, arylalkyl, arylalkylcarbonyl, carboxyalkyl, carboxyalkylcarbonyl, cycloalkyl, cycloalkylalkyl, haloalkyl, haloalkylcarbonyl, heteroaryl, heteroarylalkyl, heteroarylcarbonyl, heterocycle, heterocyclealkyl, heterocyclecarbonyl, heterocyclealkylcarbonyl, (NR A R B )alkyl, and (NR A R B )alkylcarbonyl; wherein if R C or R D are aryl, arylalkyl, arylalkylcarbonyl, arylcarbonyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroarylalkyl, heteroarylcarbonyl, heterocycle, heterocyclealkyl, heterocyclecarbonyl, or heterocyclealkylcarbonyl, then R C or R D may be unsubstituted or substituted with 1, 2, 3, 4, or 5 substituents independently selected from the group consisting of alkyl, alkenyl, alkynyl, nitro, —CN, halogen, haloalkyl, oxo, alkoxy, alkylcarbonyl, alkylcarbonylalkyl, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, aryl, arylalkyl, arylalkoxy, arylalkylcarbonyl, and arylalkoxycarbonyl; R A and R B are independently selected from the group consisting of hydrogen, alkyl, haloalkyl, and alkylcarbonyl; and n is 1.