Patent ID: 7790742

Claim:
A compound of formula I wherein: R1, R2, R3 and R4 are independently hydrogen, F, Cl, Br, I, CN, NO 2 , or R11-(C m H 2m )-A n -; m is zero, 1, 2, 3 or 4; n is zero or 1; R11 is hydrogen, methyl, C p F 2p+1 or phenyl; p is 1, 2 or 3; A is oxygen, NH, N(CH 3 ) or S(O) q ; q is zero, 1 or 2; R5 is hydrogen, an alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms which may be partially or completely fluorinated, or cycloalkyl having 3, 4, 5 or 6 carbon atoms; R6 is hydrogen, OH, F, CF 3 , methyl, ethyl, isopropyl or cyclopropyl; R7 is hydrogen, an alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms, cycloalkyl having 3, 4, 5 or 6 carbon atoms, OR12 or NR13R14; R12 is hydrogen, an alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms which may be partially or completely fluorinated, or cycloalkyl having 3, 4, 5 or 6 carbon atoms; R13 and R14 are independently hydrogen, cycloalkyl having 3, 4, 5 or 6 carbon atoms, alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms which may be partly or completely fluorinated, phenyl, phenylalkyl having 1, 2 or 3 carbon atoms in the alkyl moiety, heteroaryl or heteroarylmethyl, wherein the phenyl and heteroaryl radicals are un-substituted or substituted by 1, 2, 3, 4 or 5 substituents selected from the group consisting of fluorine, chlorine, methyl, CF 3 , methoxy and OH; and wherein the alkyl radicals are un-substituted or are substituted by 1, 2 or 3 substituents selected from the group consisting of alkoxy having 1, 2, 3 or 4 carbon atoms, NR15R16 and cycloalkyl having 3, 4, 5 or 6 carbon atoms, or R13 and R14 taken together with the nitrogen atom to which they are attached form a 3, 4, 5, 6, 7, 8 or 9-membered ring, wherein one carbon atom of the ring may be replaced by an oxygen atom or an NCH 3 group; R15 and R16 are independently hydrogen or alkyl having 1, 2, 3 or 4 carbon atoms; R8 and R9 are independently hydrogen, F, Cl, OH, CH 3 , CH 3 O, CF 3 , CF 3 CH 2 O or CH 3 SO 2 ; and R10 is hydrogen, methyl or ethyl; or a pharmaceutically acceptable salt or trifluoroacetate thereof.