Patent ID: 7745628

Claim:
Method for obtaining a pharmaceutically active compound, Dolasetron, characterised in that it comprises the following steps: a) Esterification of the alcohol of formula IV with indole-3-carboxylic acid (compound III) or a reactive derivative thereof, where R 1 and R 2 mean any linear or branched chain C 1 -C 4 alkyl group, in which the indole group can optionally be protected with a protective group of indoles, to give a compound of formula V: b) Dieckmann reaction of intermediate V, by reaction with a strong organic or inorganic base, to give the intermediate VI: c) Dealcoxycarbonylation of the intermediate VI, and optionally deprotection of the indole group, to give Dolasetron base and, if desired, a pharmaceutically acceptable salt thereof, hydrates or solvates of the base or of said salt.