Patent ID: 8883761

Claim:
A method of inhibiting the accumulation of LDL in a subject in need thereof, comprising the step of administering to said subject a composition comprising a compound of general formula (I): wherein R 1 is a linear, saturated, mono-unsaturated, or poly-unsaturated, alkyl chain ranging in length from 2 to 30 carbon atoms; R 2 is a linear, saturated, mono-unsaturated, or poly-unsaturated, alkyl chain ranging in length from 2 to 30 carbon atoms; Y is either nothing or a spacer group ranging in length from 2 to 30 atoms; X is a glycosaminoglycan; and n is a number from 2 to 1000; wherein if Y is nothing, the phosphatidylethanolamine is directly linked to X via an amide bond and if Y is a spacer, said spacer is a straight or branched chain alkylene selected from the group consisting of —CO-alkylene-CO—, —NH-alkylene-NH—, and —CO-alkylene-NH—, and said spacer is directly linked to X via an amide or an esteric bond and to said phosphatidylethanolamine via an amide bond, thereby inhibiting the accumulation of LDL in a said subject.