Patent ID: 8309554

Claim:
A compound having a structure of formula: or a pharmaceutically acceptable salt thereof, wherein each of X 1 and X 2 is independently selected from the group consisting of chloro, bromo, iodo, and sulfonate; Y is selected from the group consisting of O and NR 6 ; each of R 1 and R 2 is independently selected from the group consisting of hydrogen, halogen, and optionally substituted C 1-6 alkyl; each of R 3 and R 4 is independently selected from the group consisting of hydrogen and optionally substituted C 1-6 alkyl; R 5 is a bioreductive group selected from the group consisting of: R 6 is selected from the group consisting of hydrogen and optionally substituted C 1-6 alkyl; R 7 is selected from the group consisting of hydrogen and optionally substituted C 1-6 alkyl; R 37 is hydrogen, or together with R 7 and the carbon atoms to which they are bonded, form an optionally substituted cycloalkyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl moiety; R 8 is optionally substituted C 1-6 alkyl; and q is 0, 1, or 2.