Patent ID: 7960588

Claim:
A compound of the formula: wherein R 4 is C, CH, or N; R 5 , R 6 and R 7 are independently CH, CH 2 , O, S, N, or NR a ; X is hydroxyl, carboxylic acid, methylene carboxylic acid, alpha-substituted carboxylic acid, phosphate, phosphonate, or alpha-substituted phosphonate; R 1 is hydrogen, halo, tri-fluoromethyl, (C 1 -C 10 )alkyl, halo(C 1 -C 10 )alkyl, hydroxy-(C 1 -C 10 )alkyl, (C 1 -C 10 ) alkoxy(C 1 -C 10 )alkyl, or cyano(C 1 -C 10 )alkyl; and R 2 is hydrogen, halo, (C 1 -C 20 )alkyl, (C 1 -C 20 )alkoxy; (C 2 -C 26 ) alkoxyalkyl; (C 2 -C 20 )alkenyl, (C 2 -C 20 )alkynyl, (C 3 -C 12 )cycloalkyl, (C 1 -C 20 )alkyl-(C 3 -C 12 )cycloalkyl, (C 6 -C 10 )aryl, (C 1 -C 20 )alkyl(C 6 -C 10 )aryl, (C 6 -C 10 )aryl(C 1 -C 20 )alkyl, and aryl substituted arylalkyl; wherein one or more of the carbon atoms in the R 2 groups can be independently replaced with non-peroxide oxygen, sulfur or NR a ; the alkenyl, alkynyl, cycloalkyl, aryl, heterocyclic, or heteroaryl groups of R 1 , R 2 , or X are optionally substituted with 1, 2, 3, or 4 groups where the substituent groups are independently hydroxy, halo, cyano, (C 1 -C 10 )alkyl, (C 1 -C 10 )alkoxy, C 6 -aryl, (C 7 -C 24 )arylalkyl, oxo (═O), or imino (═NR a ); R a is hydrogen, or (C 1 -C 10 )alkyl; and n is 0, 1, 2, 3, or 4; indicates one or more optional double bonds, and the alkyl groups of R a are optionally substituted with 1, or 2 hydroxy groups; or a pharmaceutically acceptable salt or ester thereof.