Patent ID: 7196114

Claim:
A compound of formula I wherein R5 is F, Cl or Br; R1 is H, F, Cl or Br; R2 is CF 3 , OCF 3 , NO 2 , O—(C 1 –C 6 )-alkyl, CO—(C 1 –C 6 )-alkyl, COOH, CONH 2 , CONH(C 1 –C 6 )-alkyl, CON((C 1 –C 6 )-alkyl) 2 , SO 2 —(C 1 –C 6 )-alkyl, or the A radical; R3 is H, (C 1 –C 6 )-alkyl, COO(C 1 –C 6 )-alkyl, SO 2 —(C 1 –C 6 )-alkyl, (C 1 –C 6 )-alkyl-phenyl, phenyl, SO 2 -phenyl, wherein the phenyl rings of said (C 1 –C 6 )-alkyl-phenyl, phenyl and SO 2 -phenyl groups are optionally mono- or disubstituted by F, Cl, CN, OH, (C 1 –C 6 )-alkyl, O—(C 1 –C 6 )-alkyl, CF 3 , OCF 3 , COOH, COO(C 1 –C 6 )-alkyl or CONH 2 ; R4 is H, (C 1 –C 6 )-alkyl, COO(C 1 –C 6 )-alkyl, SO 2 —(C 1 –C 6 )-alkyl, SO 2 -piperidinyl, SO 2 -piperazinyl, (C 1 –C 6 )-alkylphenyl, wherein said SO 2 -piperidinyl and SO 2 -piperazinyl groups and the phenyl ring of said (C 1 –C 6 )-alkylphenyl group are optionally mono- or disubstituted by F, Cl, CN, OH, (C 1 –C 6 )-alkyl, O—(C 1 –C 6 )-alkyl, CF 3 , OCF 3 , COOH, COO(C 1 –C 6 )-alkyl or CONH 2 ; A is a heterocyclic radical of the formula 2a, 2b, 2c or 3; X is O or NH; Y is OH or NH 2 ; Z is OH, O(C 1 –C 6 )-alkyl, NH 2 , NH(C 1 –C 6 )-alkyl or N((C 1 –C 6 )-alkyl) 2 ; and pharmaceutically acceptable salts thereof.