Patent ID: 7312224

Claim:
A compound of formula I in which R 1 and R 2 are each, independently of one another, H, A, OH, OA or Hal, R 1 and R 2 together are alternatively alkylene having 3-5 carbon atoms, —O—CH 2 —CH 2 —, —CH 2 —O—CH 2 —, —O—CH 2 —O— or —O—CH 2 —CH 2 —O—, R 3 and R 4 together are —(CH 2 ) 3 —, —(CH 2 ) 4 — or —CH═CH—CH═CH—, W is H or alkyl having 1, 2, 3 or 4 carbon atoms, X is CH or N, Y is (CH 2 ) q —R 7 or R 5 , R 6 or R 9 , each of which is unsubstituted or monosubstituted by (CH 2 ) n R 20 , Z is O, NH or NA′, A′ is alkyl having 1-6 carbon atoms, —CHAr or —CHAr-A″, A″ is alkyl having 1-6 carbon atoms, R 5 is linear or branched alkyl having 1-10 carbon atoms, in which one or two CH 2 groups may be replaced by —CH═CH— groups, —C≡C— groups, —O—, CO, —S—, —SO—, SO 2 , —NH— or —NA—, R 6 is cycloalkyl or cycloalkylalkylene having 5-12 carbon atoms, R 7 is a saturated or unsaturated 5-7-membered heterocyclic radical having 1-4 N, O or S atoms which is unsubstituted or monosubstituted, disubstituted or trisubstituted by R 20 , A, Hal or CF 3 , R 9 is Ar or (CH 2 ) k —Ar, R 20 is —COOH, —COOA, —CONH 2 , —CONHA, —CONA 2 , —CN, tetrazol-5-yl, —S(O) m A, —S(O) m NH 2 or —S(O) m OH, A is alkyl or alkenyl having from 1 to 6 carbon atoms, in which 1-7 H atoms may be replaced by F, Ar is a phenyl radical which is unsubstituted or monosubstituted, disubstituted or trisubstituted by Hal, A, OA, OH, SO 2 NH 2 , SO 2 NHA, SO 2 NA 2 or CN, Hal is F, Cl, Br or I, k and q are each, independently of one another, 0, 1, 2, 3 or 4, m is 1 or 2 and n is 0, 1, 2 or 3, or a pharmaceutically acceptable salt, stereoisomer, or mixture thereof.