Patent ID: 6903238

Claim:
A compound of formula I having the structure, wherein, R 1 is hydrogen, hydroxyl, halogen, trifluoroalkyl of 1-6 carbon atoms, alkyl of 1-6 carbon atoms, cycloalkyl of 3-8 carbon atoms, alkenyl of 2-7 carbon atoms, alkoxy of 1-6 carbon atoms, trifluoroalkoxy of 1-6 carbon atoms, thioalkyl of 1-6 carbon atoms, sulfoxoalkyl of 1-6 carbon atoms, sulfonoalkyl of 1-6 carbon atoms, sulfoxoalkyl of 1-6 carbon atoms, sulfonoalkyl of 1-6 carbon atoms, —CN, —NO 2 , —CHFCN, —CF 2 CN, aryl of 6-10 carbon atoms, —NR 4 R 5 , —NCOR 4 , —SR 4 , —SOR 4 , —SO 2 R 4 , or a 5 or 6-membered heterocyclic ring having 1 to 4 heteroatoms selected from O, N or S; wherein the alkyl or alkenyl moieties are optionally substituted with hydroxyl, —CN, halogen, trifluoroalkyl of 1-6 carbon atoms, trifluoroalkoxy of 1-6 carbon atoms, —COR 4 , —CO 2 R 4 , —CONR 4 R 5 , or NR 4 R 5 ; R 2 is hydrogen, hydroxyl, alkyl of 1-6 carbon atoms, halogen, phenyl substituted with one of hydrogen, hydroxyl, halogen, trifluoroalkyl of 1-6 carbon atoms, alkyl of 1-6 carbon atoms, cycloalkyl of 3-8 carbon atoms, alkenyl of 2-7 carbon atoms, alkoxy of 1-6 carbon atoms, trifluoroalkoxy of 1-6 carbon atoms, thioalkyl of 1-6 carbon atoms, sulfoxoalkyl of 1-6 carbon atoms, sulfonoalkyl of 1-6 carbon atoms, sulfoxoalkyl of 1-6 carbon atoms, sulfonoalkyl of 1-6 carbon atoms, —CN, —NO 2 , —CHFCN, —CF 2 CN, aryl of 6-10 carbon atoms, —NR 4 R 5 , —NCOR 4 , —SR 4 , —SOR 4 , —SO 2 R 4 , or a 5 or 6-membered heterocyclic ring having 1 to 4 heteroatoms selected from O, N or S; wherein the alkyl or alkenyl moieties are optionally sustituted with hydroxyl, —CN, halogen, trifluoroalkyl of 1-6 carbon atoms, trifluoroalkoxy of 1-6 carbon atoms, —COR 4 , —CO 2 R 4 , —CONR 4 R 5 , or NR 4 R 5 , provided that when R 1 =R 3 =H, R 2 is not hydroxy phenyl, alkylthio of 1-6 carbon atoms, thioalkyl of 1-6 carbon atoms, amino, aminoalkyl of 1-6 carbon atoms, alkylamino of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, or alkenyl of 2-7 carbon atoms; R 3 is hydrogen, halogen, hydroxyl, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, trifluoroalkyl of 1-6 carbon atoms, or trifluoroalkoxy of 1-6 carbon atoms; R 4 and R 5 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, or aryl of 6-10 carbon atoms; or a pharmaceutically acceptable salt thereof.