Patent ID: 8063247

Claim:
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein X and Y are CH, or one of X and Y is N and the other is CH; R is (CR 7 R 8 ) n R 6 ; n is 0, 1, 2 or 3; when n is 0, R 6 is selected from cyclopropyl, cyclobutyl, cyclopentyl, decahydronaphthyl, 1,2,3,4-tetrahydronaphthyl, and spirofused ring systems; when n is 1, R 6 is selected from methyl, ethyl, propyl, isopropyl, butyl, sec-butyl, pentyl, hexyl, naphthyl, C 5 -C 10 heteroaryl, a 4- to 7-membered oxygen containing heterocycle, cyclopropyl, cyclobutyl, cyclopentyl, decahydronaphthyl, adamantyl, indanyl, 1,2,3,4-tetrahydronaphthyl, bi-cyclic or tri-cyclic saturated carbocycle, fused or bridged ring system, cyclohexyl substituted with one to three substituents selected from C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy and halogen, and phenyl substituted with one to three substituents selected from C 1 -C 6 alkyl and C 1 -C 6 alkoxy; when n is 2, R 6 is selected from methyl, ethyl, propyl, butyl, sec-butyl, tert-butyl, pentyl, hexyl, cyclopropyl, cyclobutyl, cyclopentyl, decahydronaphthyl, adamantyl, indanyl, 1,2,3,4-tetrahydronaphthyl, naphthyl, bi-cyclic or tri-cyclic saturated carbocycle, fused or bridged ring system, C 5 -C 10 heteroaryl, a 4- to 7-membered oxygen containing heterocycle, phenyl and cyclohexyl, wherein said phenyl or cyclohexyl is substituted with one to three substituents selected from C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy and halogen; when n is 3, R 6 is selected from ethyl, propyl, isopropyl, butyl, sec-butyl, tert-butyl, pentyl, hexyl, C 6 -C 10 aryl, C 5 -C 10 heteroaryl, C 3 -C 10 cycloalkyl, and a 4- to 7-membered oxygen containing heterocycle; wherein any R 6 groups are optionally substituted with one to three substituents selected from C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy and halogen; R 1 is hydrogen, C 1 -C 3 alkyl or halogen; R 2 is hydrogen, C 1 -C 3 alkyl or halogen; R 3 and R 4 are independently selected from hydrogen and C 1 -C 3 alkyl; R 5 is hydrogen, C 1 -C 6 alkyl or —C 2 -C 3 alkyl-O—C 1 -C 3 alkyl; and R 7 and R 8 are independently selected from hydrogen and C 1 -C 3 alkyl, or when n is 2 or 3 one of R 7 and R 8 may be hydroxy, provided the hydroxy group is not attached to the carbon adjacent to N—R 5 .