Patent ID: 8067226

Claim:
A device comprising: a substrate; a sample-distribution network defined by the substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, (iii) at least one sample delivery channel in fluid communication with the sample inlet, and (iv) a channel means providing fluid communication between the two or more detection chambers and the at least one sample delivery channel; and detection reagents in the two or more detection chambers; wherein (1) the substrate comprises two or more layers, a high thermal conductivity metal surface, and a plastic polymer on the high thermal conductivity metal surface, (2) each of the two or more detection chambers comprises an opaque lower wall that minimizes reflection, (3) each of the two or more detection chambers is at least partially defined by the plastic polymer, (4) the plastic polymer prevents corrosion of the high thermal conductivity metal surface, and (5) the plastic polymer separates the high thermal conductivity metal surface from each of the two or more detection chambers such that the high thermal conductivity metal surface does not contact the detection reagents.