Patent ID: 8883093

Claim:
A system ( 20 ) comprising a bioassay cartridge ( 4 ), comprising at least one reaction chamber ( 6 ) containing bioaffinity reagents in a dried state, and a piercable hermetic cover ( 2 ) not allowing, before being pierced, any flow or diffusion of matter to or from said reaction chamber ( 6 ) through said cover ( 2 ), wherein a) said cover ( 2 ) comprises at least a top layer ( 8 ), a middle layer ( 10 ), a bottom layer ( 12 ), and a site intended for piercing ( 14 ); b) said top layer ( 8 ) and bottom layer ( 12 ) are spaced apart by a constant distance from each other; c) when said cartridge ( 4 ) is covered with said cover ( 2 ) said bottom layer ( 12 ) is against said cartridge ( 4 ), and said site ( 14 ) is at an opening ( 16 ) of reaction chamber ( 6 ); d) said cover ( 2 ) has, at the site ( 14 ), a hollow space ( 18 ) between said top layer ( 8 ) and said bottom layer ( 12 ), and which extends through said middle layer ( 10 ); and e) either said top layer ( 8 ) or said bottom layer ( 12 ) is hermetic until piercing; and either said bottom layer ( 12 ) or top layer ( 8 ), respectively, is pre-scored, such that i) when being pierced by a needle, a pierce joint is created which is not gas tight but instead allows gas to freely flow out from the reaction chamber ( 6 ), and ii) said layer ensures a tight closing of a needle track upon retraction of said needle.