Patent ID: 8710010

Claim:
A peptide with general formula (I) R 1 -AA 2 -AA 3 -AA 4 -R 2 (I) its stereoisomers, mixtures thereof, or its cosmetically or its pharmaceutically acceptable salts comprising: AA 1 is selected from the group consisting of -Lys-, -Orn-, -Dab-, -Dpr-, -Agl-, -3,4-dehydrolysine and -4,5-dehydrolysine; AA 2 is -Ala-; AA 3 is selected from the group consisting of -Asp-, -Ala-, -Asn-, -Glu- and -Pro-; AA 4 is -His-; R 1 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and R 5 —CO—; and R 2 is selected from the group consisting of —NR 3 R 4 , —OR 3 and —SR 3 ; where R 3 and R 4 are independently selected from the group consisting of H, unsubstituted noncyclic aliphatic group, substituted or unsubstituted alicycyl, unsubstituted heterocyclyl, unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, and unsubstituted aralkyl; and where R 5 is selected from the group consisting of H, substituted or unsubstituted noncyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted heterocyclyl and substituted or unsubstituted heteroarylalkyl, and wherein when R 1 or R 5 is a substituted non-cyclic aliphatic group, each substituent of said substituted non-cyclic aliphatic group is selected from the group consisting of hydroxyl , C 1 -C 4 alcoxyl, C 1 -C 4 oxycarbonyl, halogen, cyano, nitro, azido, C 1 -C 4 alkylsulfonyl, thiol, alkylthio, aryloxyl, and -NR b (C=NR b )NR b R c , where R b and R c are independently selected from the group consisting of H, C 1 -C 4 alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 3 -C 10 cycloalkyl, C 6 -C 18 aryl, C 7 -C 17 aralkyl, and 3-10-membered-heterocyclyl.