Patent ID: 8598212

Claim:
A method of treating Alzheimer's disease comprising administering a therapeutically effective amount of a cyclohexane derivative represented by the Formula (I): wherein A is a substituent represented by the Formula (IIa) or (IIb): R 1 and R 2 are each independently a hydrogen atom, a chlorine atom, a C 1 -C 3 haloalkyl group, a C 1 -C 4 alkyl group or a C 1 -C 4 alkoxy group; R 3 is a hydrogen atom or a chlorine atom; R 4 is a fluorine atom, a hydroxymethyl group or a hydroxyl group; R 5 and R 6 are each independently a hydrogen atom, a fluorine atom, a C 1 -C 3 haloalkyl group, a carboxyl group, a methoxycarbonyl group, an ethoxycarbonyl group, a C 1 -C 4 alkoxy group, a hydroxyl group or a C 2 -C 5 alkylcarbonyloxy group, or optionally together form an oxo group; R 7 and R 8 are each independently a hydrogen atom or a fluorine atom; Y is an oxygen atom or a sulfur atom; Z is a nitrogen atom or a methine group or a pharmaceutically acceptable salt thereof or a prodrug thereof.