Patent ID: 6900048

Claim:
An apparatus for fabricating an addressable array of biopolymers on a substrate according to a target pattern, comprising: (a) a deposition system which can separately dispense onto a substrate, fluid compositions of different biomonomers each with a first linking group which must be activated for linking to a substrate bound moiety, and a fluid composition of a solid activator; (b) a processor to operate the deposition system, which processor derives from the target array pattern a target drive pattern for operating the deposition system to form the array, the target drive pattern comprising instructions to the deposition system to perform the following at each of multiple regions at which a biomonomer is to be deposited: (i) deposit the fluid composition of solid activator separate from and preceding deposition of the biomonomer; (ii) allow sufficient time for evaporation to leave solid activator at the region; and (iii) then deposit the biomonomer.