Patent ID: 8455211

Claim:
A method of detecting the presence of an anti- Anaplasma translocated substrate-1 (Ats-1) antibody against Anaplasma phagocytophilum in a biological sample of a patient suspected of having an infection of Anaplasma phagocytophilum , comprising the steps of: (i) immobilizing an isolated Ats-1 protein antigen onto a surface of a support; (ii) contacting said immobilized Ats-1 protein with a biological sample from a patient suspected of containing an anti-Ats-1 antibody against Anaplasma phagocytophilum , under conditions that allow formation of a complex of the antibody and the protein antigen; and (iii) detecting the formation of said antibody-protein antigen complex, wherein said detected antibody-protein antigen complex is indicative of the presence of said anti-Ats-1 antibody against Anaplasma phagocytophilum in said biological sample of said patient.