Patent ID: 6906073

Claim:
A compound of Formula (I): wherein: R 1 is (C 1 -C 2 )alkylene; R 2 is a phenyl group which is optionally substituted with one or more substituents selected from the group consisting of alkyl, haloalkyl, hydroxyalkyl, heteroalkyl, acyl, acylamino, amino, alkylamino, dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, —SO 2 NR′R″ (where R′ and R″ are independently hydrogen or alkyl), alkoxy, haloalkoxy, alkoxycarbonyl, carbamoyl, hydroxy, halo, nitro, cyano, mercapto, methylenedioxy or ethylenedioxy; R 3 is hydrogen, alkyl, acyl, aryl, or arylalkyl; ring A is a heterocyclyl, or optionally a phenyl group which is optionally substituted with one or more substituents selected from the group consisting of alkyl, haloalkyl, hydroxyalkyl, heteroalkyl, acyl, acylamino, amino, alkylamino, dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, —SO 2 NR′R″ (where R′ and R″ are independently hydrogen or alkyl), alkoxy, haloalkoxy, alkoxycarbonyl, carbamoyl, hydroxy, halo, nitro, cyano, mercapto, methylenedioxy or ethylenedioxy; L is —C(═O)—, —C(═S)—, —SO 2 —, —C(═O)N(R a )—, —C(═S)N(R a )—, —SO 2 N(R a )—, —C(═O)O—, —C(═S)O—, —S(═O) 2 O—; where R a is hydrogen, alkyl, acyl, aryl, arylalkyl, alkoxycarbonyl, or benzyloxycarbonyl; X is absent, —(CR′R″)O—, —(CR′R″)S—, —(CR′R″)NR b — or alkylene; where R′ and R″ are independently hydrogen or alkyl, and R b is hydrogen or alkyl; R 4 is aryl or heteroaryl; and prodrugs, individual isomers, racemic and non-racemic mixtures of isomers, and pharmaceutically acceptable salts and solvates thereof.