Patent ID: 7622456

Claim:
A method for inhibiting DSG3 expression in cancer individuals by using a RNA jamming sequence to inhibit cell growth, invasion and migration in head neck cancer (HNC), wherein the method comprises the steps of: (a) designing a RNA jamming sequence, named DSG3-RNAi, wherein the DSG3-RNAi is set forth in SEQ ID NO: 2; (b) synthesizing two clones of DSG3-RNAi comprising SEQ ID NO: 2 in the structure of symmetrical complementary sequence, wherein one clone is set forth in SEQ ID NO: 3 and the other clone is set forth in SEQ ID NO: 4; (c) linking SEQ ID NO: 3 and SEQ ID NO: 4 into an expression vector and making a plasmid comprising the expression vector; (d) transfecting the plasmid into cancer individuals respectively for inhibiting cell growth of cancer.