Patent ID: 8613952

Claim:
A tissue adhesive composition, comprising an adhesive comprising 85 v % of a cyanoacrylate monomer selected from the group consisting of methoxyisopropylcyanoacrylate and a combination of octylcyanoacrylate and methoxyisopropylcyanoacrylate in a 50:50 v % ratio, and 15 v % of polyethylene glycol (PEG) that remains a polyether in the adhesive, and polymerized cyanoacrylate nanoparticles containing an effective amount of a therapeutic agent, wherein said nanoparticles are homogenously mixed together and miscible with the adhesive, and when mixed together with the adhesive, remain miscible in the adhesive and do not initiate polymerization of the cyanoacrylate monomer.