Patent ID: 8828980

Claim:
A pharmaceutical composition comprising (i) a copolymer of polyoxyethylene and polyoxypropylene in an amount sufficient to provide a gelation temperature of between about 19° C. and about 42° C., a gelation viscosity between about 15,000 cP and about 1,000,000 cP; and a non-gelation viscosity that allows injection with a 18-31 gauge needle through the tympanic membrane on or near the round window membrane; (ii) between about 1-70 mg/mL of a multiparticulate anti-inflammatory corticosteroid; and (iii) having an osmolarity from 100 to 1000 mOsm/L; wherein the composition provides a sustained release of the corticosteroid in to the inner ear for a period of at least 5 days after a single administration.