Patent ID: 8349587

Claim:
An engineered cell for producing a carbon-based product, comprising: an at least partially engineered energy conversion pathway having a recombinant formate dehydrogenase or a recombinant sulfide-quinone oxidoreductase introduced into a host cell, wherein the recombinant formate dehydrogenase is encoded by SEQ ID NO:1-4 or a homolog thereof having at least 80% sequence identity thereto, or comprises any one of SEQ ID NOs:5-8 or a homolog thereof having at least 80% sequence identity thereto, the recombinant sulfide-quinone oxidoreductase is encoded by any one of SEQ ID NOs:9-16 or a homolog thereof having at least 80% sequence identity thereto, and said energy conversion pathway is capable of using energy from oxidation to produce a reduced cofactor; a carbon fixation pathway that is capable of converting inorganic carbon to a carbon-based central metabolite using energy from the reduced cofactor; and optionally, a carbon product biosynthetic pathway that is capable of converting the carbon-based central metabolite into a carbon-based product of interest.