Patent ID: RE39069

Claim:
An improved A multi-layered osmotic device for the controlled delivery of one or more active agents to one or more environments of use wherein the osmotic device comprises: a) a compressed core comprising a first active agent and an osmotic agent for controlled and continuous release of the drug first active agent ; b) a semipermeable membrane surrounding the core and having a preformed passageway therein, said semipermeable membrane being permeable to a fluid in the environment of use and substantially impermeable to the first active agent; c) an inert, completely erodible or water soluble polymer coat comprising poly(vinylpyrrolidone)-(vinyl acetate) copolymer partially or substantially completely surrounding the semipermeable membrane and plugging the passageway in the wall semipermeable membrane ; and d) an external coat comprising a second active agent for immediate release of the drug second active agent , wherein the first active agent is released from the core after the polymer coat has partially or completely dissolved or eroded, and the first and second active agents are released into the same or different environments of use to provide a controlled delivery of the one or more active agents.