Patent ID: 8883166

Claim:
A vaccine composition comprising: (i) a diphtheria toxoid, ‘D’; (ii) a tetanus toxoid, ‘T’; (iii) a cellular pertussis antigen, ‘wP’; (iv) a hepatitis B virus surface antigen, ‘HBsAg’; (v) a Haemophilus influenzae type b (‘Hib’) capsular saccharide conjugated to a carrier protein; and (vi) at least one Neisseria meningitidis capsular saccharide conjugated to a carrier protein, wherein the at least one Neisseria meningitidis capsular saccharide comprises an O-acetyl (OAc+) Neisseria meningitidis serogroup C capsular saccharide, wherein the H. influenzae type b capsular saccharide and the N. meningitidis capsular saccharide(s) are each conjugated to a tetanus toxoid carrier protein, or the N. meningitidis capsular saccharide(s) is conjugated to a tetanus toxoid, diphtheria toxoid, or CRM197 carrier protein, and wherein the conjugate of component (v) has a weight excess of carrier, and wherein the weight ratio of saccharide to carrier is between 1:2 and 1:4.