Patent ID: 7572821

Claim:
A compound represented by formula (IA): or a pharmaceutically acceptable salt, thereof, wherein: one of R a or R b is —H and the other is an optionally substituted phenyl; and R x is (R aa ) m , —R aa —C(O)(CH 2 ) n C(O)OH, —C(O)(CH 2 ) n C(O)OH, —C(O)YR z , —C(O)NH—R aa , or —(R aa ) q C(O)(Y 1 ); R y is —H or lower alkyl; R W is —H, an alkyl, an alkenyl, an alkynyl, cyano, a haloalkyl, an alkoxy, a haloalkoxy, a halo, an amino, an alkylamino, a dialkylamino, —OP(O)(OR 7 ) 2 , —SP(O)(OR 7 ) 2 , nitro, an alkyl ester, or hydroxyl; R 7 , for each occurrence, is independently —H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl, or an optionally substituted heteraralkyl; R aa is an amino acid residue or an amino acid residue analog; Y is CH 2 , O, or NH; R Z is Alk-NH 2 , Alk-C(O)OH, Het, or Y 1 ; Alk is an optionally substituted alkylene; Het is an optionally substituted heteroalkyl; Y 1 is a water soluble polymer with a molecular weight less than 60,000 daltons; n is 1, 2, 3, or 4; m is an integer from 1 to 10; and q is 0 or 1.