Patent ID: 8241893

Claim:
A device for analyzing molecular targets contained in a complex mixture, said device comprising: a capillary network allowing primary probes of different types to circulate, each type of primary probe being capable of being bound by a specific bond to one type of target among said molecular targets, a matrix of secondary probes organized in spots inside said capillary network and capable of retaining a specific type of primary probe by specific bonding, a network of functionalized electrodes, onto which the secondary probes are attached, this network being set out in such a way that each line of spots of the spot matrix is linked to one of the functionalized electrodes of said network, and a network of non-functionalized electrodes, which is disposed in such a way that the capillary network is situated between the two networks of electrodes, wherein said network of functionalized electrodes is formed by a square mesh pattern of superimposed and coplanar line and column electrodes, and contains, in each square of the mesh, one spot electrode onto which the secondary probes are attached and which is connected to a line electrode and a column electrode of the mesh by a first field effect transistor, said first field effect transistor having a transistor drain connected to said spot electrode, a transistor grid connected to said line electrode and a transistor source connected to said column electrode, and wherein said networks of non-functionalized electrodes is formed by a square mesh pattern of superimposed and coplanar line and column electrodes, and contains, in each square of the mesh, one spot electrode connected to a line electrode and a column electrode of the mesh by a second field effect transistor, said second field effect transistor having a transistor grid connected to said spot electrode, a transistor drain connected to said line electrode and a transistor source connected to said column electrode, so that the field effect transistor acts as a detector, said second field effect transistor being configured so that a state of closure of said second field effect transistor is modified in function of electrical potential or current variation induced at its transistor grid when a voltage is applied to the spot electrode of the first field effect transistor.