Patent ID: 7893278

Claim:
A compound of formula or the pharmaceutically acceptable salts thereof, wherein R is selected from saturated and unsaturated 5- and 6-membered rings containing at least one hetero atom wherein the hetero atom is selected from S, N or O and said ring being substituted with a lower alkyl which alkyl is further substituted with at least one group selected from —C═O—R 1 , —SO 2 CH 3 , or —CH 2 C═OCH 3 , R 1 is selected from the group consisting of hydrogen, —NH 2 , —N-lower alkyl, lower alkyl substituted with hydroxy, lower alkyl substituted with NH 2 , and a 5- or 6-membered saturated ring containing at least one hetero atom selected from S, N and O, X 1 and X 2 are independently selected from the group consisting of hydrogen, lower alkoxy, —CH 2 OCH 3 , —CH 2 OCH 2 CH 3 , —OCH 2 CF 3 and —OCH 2 CH 2 F, Y 1 and Y 2 are each independently selected from the group consisting of —Cl, —Br, —NO 2 , —C≡N, and —C≡CH, and the absolute stereochemistry at the 4 and 5 position of the imidazoline ring are S and R respectively.