Patent ID: 7166086

Claim:
A method for delivering substance into skin via an abrasion device comprising the steps of: providing an abrader having a plurality of microprotrusion arrays, each array having a plurality of frustoconical protrusions, each protrusion having at least one scraping edge, wherein the frustroconical protrusions within each individual array have aligned scraping edges and each array is positioned within the abrader such that the scraping edges of each array are not aligned with the scraping edges of another array; positioning the abrader device at a delivery site on the skin of a patient; applying a substance to the skin of a patient at the delivery site; and, mechanically rotating the protrusions of the abrader device against the skin with sufficient force to disrupt and substantially penetrate the stratum corneum of the skin, thereby creating intersecting furrows in the skin by the rotation of scraping edges of the abrader.