Patent ID: 7041506

Claim:
A cell culture system comprising a pentameric peptide which enhances cell growth and/or secretion, wherein said peptide comprises a pentameric structure of at least one of(a) xxxkx, (b) xxkxx, (c) xxxxk, (d) xkxxx, and (e) kxxxx, wherein k represents lysine and each x may be the same or different amino acid independently selected from the group consisting of lysine, alanine, isoleucine, phenylalanine, proline, valine, glycine, glutamine, leucine, methionine, asparagine, serine, threonine, tyrosine, aspartic acid, glutamic acid, histidine, and derivatives thereof, and wherein said peptide is covalently linked to a growth factor, wherein said growth factor comprises at least one of bFGF, GCSF, an ILGF-1, or VEGF.