Patent ID: 7655793

Claim:
A process for separating and/or purifying a genomic DNA, comprising: a) contacting an aqueous solution containing the genomic DNA with an anion exchanger bound to a solid support matrix under conditions such that the anion exchanger binds the genomic DNA; and b) eluting the anion exchanger with an aqueous mobile phase comprising a basic genomic DNA elution salt solution; wherein the basic elution salt solution comprises an additive having the formula (I): wherein: R is a moiety selected from the group consisting of hydrogen, a lower alkyl, optionally substituted by amino, and the group: where n is 1, 2 or 3; wherein the presence of the additive in the elution solution increases the pH of said aqueous mobile phase to between about pH 10 and about pH 13, and thereby provides an increase in the recovery of genomic DNA from the anion exchanger, as compared with the recovery of the genomic DNA from the same anion exchanger and in the absence of the additive in the elution solution, all other conditions being equal.