Patent ID: 7160914

Claim:
A compound of Formula I: wherein: X is NH; Y is N; A is N; B is NH; R 1 is selected from the group consisting of H, loweralkyl, halogen, oxyalkyl, oxyaryl, and oxyarylakyl; R 2 and R 9 are each independently selected from the group consisting of H, H 2 , hydroxy, lower alkyl, cycloalkyl, aryl, alkylaryl, alkoxyalkyl, hydroxycyoloalkyl, alkoxycycloalkoxy, hydroxyalkyl, aminoalkyl and alkylaminoalkyl; and R 3 , R 4 , R 13 and R 14 are each independently selected from the group consisting of H, lower alkyl, alkoxyalkyl, cycloalkyl, aryl, alkylaryl, hydroxyalkyl, aminoalkyl, and alkylaminoalkyl, or R 3 and R 4 together or R 13 and R 14 together represent a C 2 to C 10 alkyl, hydroxyalkyl, or alkylene, or R 3 and R 4 together or R 13 and R 14 together are: wherein n is a number from 1 to 3, and R 10 is H or —CONHR 11 NR 15 R 16 , wherein R 11 is lower alkyl and R 15 and R 16 are each independently selected from the group consisting of H and lower alkyl; L is selected from the group consisting of: wherein R 5 , R 6 , R 7 , and R 8 are each individually selected from the group consisting of H, alkyl, halo, aryl, arylalkyl, aminoalkyl, aminoaryl, oxoalkyl, oxoaryl, and oxoarylalkyl; and wherein said compound of Formula I binds the minor groove of DNA as a dimer.