Patent ID: 7795316

Claim:
A topical ophthalmic composition, comprising: 0.1 to 0.5 w/v % tobramycin; 0.03 to 0.1 w/v % of dexamethasone; an aqueous, ophthalmically acceptable vehicle containing deacetylated xanthan gum at a concentration of 0.3 to 0.9%; and one or more ionizable species in an amount sufficient to limit ionic interactions between the tobramycin and the deacetylated xanthan gum, such that the in vitro viscosity of the composition is maintained within the range of 10 to 300 cps at a shear rate of 6 sec −1 and a temperature of 25° C.; wherein the ionizable species has a sodium chloride equivalent ionic concentration range of 134 to 150 mM; said composition has a pH of 5 to 6.