Patent ID: 6900236

Claim:
A compound of the formula: including any optical isomers, and physiologically acceptable salts of the compound or any optical isomer, wherein, Z may be in the 4-, 5-, 6- or 7-position and is selected from nitro, nitroso, amino, alkylamino, dialkylamino, azido, cyano, isothiocyano and phenyl; X is selected from halogen; hydrogen; hydroxy, lower alkanoate, formyl, amino, cyano, isothiocyano, OTs and azido; R 1 is selected from a saturated or unsaturated C2-C7 straight carbon chain and a saturated or unsaturated C2-C7 branched carbon chain; R 2 is selected from H and lower alkyl; Y is selected from carbonyl and CH═CH (cis or trans); and when X is halogen R 3 is selected from phenyl, napthyl, 9-anthracenyl, adamantyl, pyrenyl, phenyl with no more than two substituents selected from nitro, nitroso, amino, alkylamino, dialkylamino, hydroxy, methoxy, lower alkyl, azido, cyano and isothiocyano, napthyl with no more than two substituents selected from nitro, nitroso, amino, alkylamino, dialkylamino, hydroxy, methoxy, lower alkyl, azido, cyano and isothiocyano and 9-anthracenyl with no more than two substituents selected from nitro, nitroso, amino, alkylamino, dialkylamino, hydroxy, methoxy, lower alkyl, azido, cyano and isothiocyano, or when X is not halogen R 3 is selected from phenyl, napthyl, 9-anthracenyl, adamantyl, pyrenyl, phenyl with no more than two substituents selected from halogen, nitro, nitroso, amino, alkylamino, dialkylamino, hydroxy, methoxy, lower alkyl, azido, cyano and isothiocyano, napthyl with no more than two substituents selected from halogen, nitro, nitroso, amino, alkylamino, dialkylamino, hydroxy, methoxy, lower alkyl, azido, cyano and isothiocyano and 9-anthracenyl with no more than two substituents selected from halogen, nitro, nitroso, amino, alkylamino, dialkylamino, hydroxy, methoxy, lower alkyl, azido, cyano and isothiocyano.