Patent ID: 7560253

Claim:
A method for detecting the level of expression of a hemopoietic linkage switch-5 (HLS-5) polynucleotide in a biological sample from a suspected or known cancer patient comprising: (a) providing a biological sample from the patient comprising a nucleic acid; (b) contacting, under stringent hybridizing conditions, the biological sample with a polynucleotide probe or primer capable of hybridizing to an HLS-5 polynucleotide selected from the group consisting of: (i) polynucleotides comprising the nucleotide sequence set out in SEQ ID NO:1 or SEQ ID NO:3; (ii) polynucleotides fully complementary to the polynucleotides of (i); and (iii) polynucleotides encoding an HLS-5 polypeptide comprising at least 95% sequence identity with the sequence set out in SEQ ID NO:2 or SEQ ID NO:4; (c) determining a total amount of duplex formed in the sample between the probe or primer and HLS-5 polynucleotide selected from the group consisting of (b)(i), (b)(ii), and (b)(iii); and (d) comparing the total amount of duplex in step (c) to a control or standard comprising a known amount of an HLS-5 polynucleotide found in a comparable biological sample taken from a non-cancer patient.