Patent ID: 8119143

Claim:
A single dose multivalent combination vaccine comprising an immunogenic composition that comprises 4 μg to 400 μg recombinant PCV2 ORF2 protein per dose, at least one immunogenic active component against Mycoplasma hyopneumoniae , Porcine Reproductive and Respiratory Syndrome Virus, or a combination thereof, and a polymer of acrylic or methacrylic acid, wherein said single dose immunogenic composition provides protective immunity and is effective for lessening the severity of one or more clinical symptoms associated with PCV2 infection after the administration of a single dose of said immunogenic composition, compared to those swine not receiving said immunogenic composition and wherein said one or more clinical symptoms are selected from the group consisting of wasting, paleness of the skin, unthriftiness, respiratory distress, diarrhea, icterus, jaundice, lung lesions, nasal shedding, cough, diarrhea and combinations thereof.