Patent ID: 7456197

Claim:
A compound useful as a gene transfer agent, the compound having Formula I: wherein R 1 is selected from the group consisting of C 1-25 alkyl; C 2-25 alkenyl; C 2-25 alkynyl; C 1-25 alkoxy; C 1-25 alkylaminomethyl; C 1-25 dialkylaminomethyl; phenyl; phenyl substituted with one or more substitutents selected from the group consisting of C 1-5 alkyl, C 2-5 alkenyl, C 2-5 alkynyl, C 1-5 alkoxy, and C 1-5 amino; styryl; and styryl substituted with one or more substitutents selected from the group consisting of C 1-25 alkyl, C 2-25 alkenyl; C 2-25 alkynyl, C 1-25 alkoxy, and C 1-25 dialkylamino; R 2 and R 3 are C 1-25 alkyl, C 2-25 alkenyl; or C 2-25 alkynyl; wherein X is selected from the group consisting of halogen, perchlorate, tetrafluoroborate, trifluoromethanesulfonate, methanesulfonate, p-toluenesulfonate, methosulfate, sulfoacetate, acetate, trifluoroacetate, hemisuccinate and hexafluorophosphate, and wherein Z is wherein R 4 and R 5 are independently selected from the group consisting of C 1-25 alkyl, C 2-25 alkenyl; C 2-25 alkynyl; C 1-25 acyl, perfluoro C 1-25 alkyl; perfluoro C 1-25 acyl; poly(ethyleneoxy)alkyl, poly(ethyleneoxy)acyl, and cholesteryloxycarbonyl.