Patent ID: 7524849

Claim:
A compound of Formula (I) wherein: Z is selected from: and C 6 -C 8 cycloalkyl; R is a moiety n is an integer of 2, 3, or 4; L 1 and L 2 , are each independently H, F, Cl or Br; L 3 and L 4 are H; X is Cl or Br; Y is O, S, or —NR 2 ; Q is OH or —NR 3 R 4 ; R 1 is H or C 1 -C 3 alkyl; R 2 is H or C 1 -C 3 alkyl; R 3 and R 4 are each independently H or C 1 -C 3 alkyl; or R 3 and R 4 when optionally taken together with the nitrogen atom to which each is attached form a saturated 4 to 6 member heterocyclic ring which contains 1-2 nitrogen atoms, 0-1 oxygen atoms and 0-1 sulfur atoms within the ring where said ring is optionally substituted with R 7 ; R 5 is CF 3 or C 2 F 5 ; W′ is —NHR 6 , —N(CN)R 6 , aryl of 6 to 12 carbon atoms optionally substituted with 1-3 groups independently selected from halogen, azido, nitro, cyano, hydroxy, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, amino, C 1 -C 3 alkylamino, C 1 -C 3 dialkylamino, formyl, C 1 -C 3 alkoxycarbonyl, carboxyl, C 1 -C 3 alkanoyl, C 1 -C 3 alkylthio, C 1 -C 3 alkylamido, phenyl, phenoxy, benzyl, benzoxy, furyl, and cyclopropyl groups; or heteroaryl of 5 to 10 ring atoms having from 1 to 4 heteroatoms selected from S, O and N and optionally substituted with 1-3 groups independently selected from halogen, azido, nitro, cyano, hydroxy, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, amino, C 1 -C 3 alkylamino, C 1 -C 3 dialkylamino, formyl, C 1 -C 3 alkoxycarbonyl, carboxyl, C 1 -C 3 alkanoyl, C 1 -C 3 alkylthio, C 1 -C 3 alkylamido, phenyl, phenoxy, benzyl, benzoxy, furyl, and cyclopropyl groups; R 6 is C 1 -C 3 alkyl; R 7 is C 1 -C 3 alkyl; or a pharmaceutically acceptable salt thereof.