Patent ID: 8642541

Claim:
A compound having the formula R 1 —X—Z—R 2 wherein R 1 is H, C 1-4 alkyl, acetyl, formyl, benzoyl or trifluoroacetyl; R 2 is OH or NH 2 ; X is a peptide which has the formula I: (SEQ ID NO: 4) His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Leu- Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Lys-Asp-Phe-Ile-Glu- Trp-Leu-Glu-Ser-Ala or differs from formula I at up to 4 of the following positions whereby, if different from formula I: the residue at position 20 is selected from: Gln, Glu; the residue at position 23 is: Val; the residue at position 24 is selected from: Gln, Lys; the residue at position 27 is: Met; the residue at position 28 is selected from: Asn, Arg; and the residue at position 29 is: Thr; and Z is absent or a peptide sequence of 1-20 amino acid units selected from the group consisting of Ala, Leu, Ser, Thr, Tyr, Cys, Glu, Lys, Arg, Dbu, Dpr and Orn; or a pharmaceutically acceptable salt thereof.