Patent ID: 7919254

Claim:
A method for detecting the presence of a cellular target protein and a cellular target nucleic acid associated with an identified cell type in a tissue sample, comprising the steps of: (a) applying a morphological stain to said tissue sample effective to provide a stained tissue sample; (b) identifying a cell type in said stained tissue sample; (c) contacting a section of the tissue sample with an antibody which specifically binds to the target protein associated with the identified cell type in the tissue sample; (d) determining binding of the antibody to the section of tissue sample; (e) hybridizing a labeled nucleic acid probe to the target nucleic acid in the same section of tissue sample; (f) detecting the presence of the labeled nucleic acid probe in the identified cell type in the section of tissue sample; and (g) comparing the results of step (d) with the results of step (f), whereby the presence of the cellular target protein and the cellular target nucleic acid associated with the identified cell type in the tissue sample is detected.