Patent ID: 6982286

Claim:
A compound having the Formula I: or an isomer or a pharmaceutically acceptable solvate, hydrate, or salt thereof; wherein: R 1 is hydrogen or (C 1 -C 4 )alkyl, aralkyl, (C 2 -C 5 )alkanoyl, aroyl or heteroaroyl; R 2 is hydrogen, optionally substituted (C 1 -C 4 )alkyl, or optionally substituted aralkyl; R 3 -R 5 and R 10 , which can be the same or different, are hydrogen, optionally substituted (C 1 -C 4 )alkyl, optionally substituted aralkyl, optionally substituted phenyl or optionally substituted heteroaryl; R 3 and R 10 are cis or trans arranged; R 11 is hydrogen, (C 1 -C 4 )alkyl, (C 2 -C 5 )alkanoyl or aralkyl; R 6 -R 9 , which can be the same or different, are hydrogen, optionally substituted (C 1 -C 4 )alkyl, halogen, hydroxy, optionally substituted (C 14 -C 4 )alkoxy, optionally substituted aralkyloxy, or (C 1 -C 4 )alkylamino; n is 1 or 3, provided that R 1 is not methyl when R 2 is methyl, n is 1 and R 3 to R 11 are hydrogen.