Patent ID: 8560038

Claim:
A method, comprising: receiving, using one or more processors, a signal associated with a monitored analyte level from an in vivo analyte sensor; retrieving, using the one or more processors, a predetermined number of stored signals associated with the monitored analyte level; processing, using the one or more processors, the received signal and the retrieved predetermined number of prior analyte level signals to determine a tolerance parameter; comparing, using the one or more processors, the tolerance parameter to a predetermined tolerance range corresponding to a dynamically varying uncertainty parameter determined based upon a number of data available for determining a rate of change of the monitored analyte level; and determining, using the one or more processors, a glucose trend information based on the received signal and the retrieved predetermined number of stored signals when the tolerance parameter is within the predetermined tolerance range such that no more than a predetermined number of the retrieved predetermined number of stored signals is missing, wherein the tolerance parameter is related to a temporal spacing of the received signal and the retrieved stored signals.