Patent ID: 8420115

Claim:
An oral preparation comprising: a complex having a particle size of 10 to 1,000 μm, which is obtained by dispersing or dissolving clarithromycin and aminoalkylmethacrylate copolymer E in molten glyceryl monostearate and granulating the resulting mixture; and a coating composition comprising aminoalkylmethacrylate copolymer RS and carboxymethylcellulose sodium at a weight ratio of from 80:20 to 99:1 and polysorbate 80 and applied on said complex to form a coating film on said complex through curing at 35 to 45 °C., wherein the surface of said coating composition is treated with at least one inorganic compound selected from the group consisting of magnesium oxide, talc and light anhydrous silicic acid prior to curing.