Patent ID: 7771730

Claim:
A method of detecting hantavirus antibodies in a biological sample, comprising: (a) contacting said biological sample with at least six hantavirus recombinant antigens, wherein the at least six hantavirus recombinant antigens comprise a combination of N antigens from hantavirus serotypes Hantaan (HTNV), Puumala (PUUV), Seoul (SEOV), Dobrava (DOBV), Sin Nombre (SNV) and Andes (ANDY) wherein at least one recombinant antigen from each of the serotypes is present, said contacting performed under conditions which allow hantavirus antibodies, when present in the biological sample, to bind to at least one of said N antigens to form an antibody/antigen complex, and wherein said N antigens comprise one or more amino acid sequences selected from the group consisting of SEQ ID NO:28, SEQ ID NO:32, SEQ ID NO:34, SEQ ID NO:48, SEQ ID NO:49, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO:52 and SEQ ID NO:53; and (b) detecting the presence or absence of said antibody/antigen complex, thereby detecting the presence or absence of hantavirus antibodies in said sample.