Patent ID: 7763627

Claim:
A compound according to Formula IV or a pharmaceutically acceptable salt thereof, wherein X is selected from —H, —OR 6 , —S(O) 0-2 R 6 , —(R 6 )R 7 , —O—N(R 6 )R 7 , —N(R 6 )R 6 , —N(R 6 )N(R 6 )R 7 , absent, oxo, thiono, and imino; R 1 and R 2 , at each occurance, are each independently selected from —H, halogen, —CN, —NH 2 , —NO 2 , —OR 6 , —N(R 6 )R 7 , —S(O) 0-2 R 7 , —SO 2 N(R 6 )R 7 , —CO 2 R 6 , —C(O)N(R 6 )R 7 , —N(R 6 )SO 2 R 7 , —N(R 6 )C(O)R 7 , —N(R 6 )CO 2 R 7 , —C(O)R 6 , optionally substituted lower alkyl, optionally substituted aryl, optionally substituted lower arylalkyl, optionally substituted heterocyclyl, absent, and optionally substituted lower heterocyclylalkyl; optionally, two of R 1 are paired, together with the corresponding atom or atoms of the ring to which they are attached to form a second ring consisting of three and seven annular carbon atoms, said second ring optionally substituted with between zero and three of R 1 ; R 3 is selected from —H and optionally substituted lower alkyl; each of R 4 is independently selected from —H, halogen, —CN, —NH 2 , —NO 2 , —OR 6 , —N(R 6 )R 7 , —S(O) 0-2 R 7 , —SO 2 N(R 6 )R 7 , —CO 2 R 6 , —C(O)N(R 6 )R 7 , —N(R 6 )SO 2 R 7 , —N(R 6 )C(O)R 7 , —N(R 6 )CO 2 R 7 , —C(O )R 6 , optionally substituted lower alkyl, optionally substituted aryl, optionally substituted lower arylalkyl, optionally substituted heterocyclyl, and optionally substituted lower heterocyclylalkyl; n is zero to four; each R 5 is independently selected from —H, halogen, —CN, —NH 2 , —NO 2 , —OR 6 , —NR 6 R 7 , —S(O) 0-2 R 7 , —SO 2 NR 6 )R 7 , —CO 2 R 6 , —C(O)NR 6 R 7 , —N(R 6 )SO 2 R 7 , —N(R 6 )C(O)R 7 , —N(R 6 )CO 2 R 7 , —C(O)R 6 , optionally substituted lower alkyl, optionally substituted aryl, optionally substituted lower arylalkyl, optionally substituted heterocyclyl, and optionally substituted lower heterocyclylalkyl; and R 6 is —H or optionally substituted lower alkyl; R 7 is selected from optionally substituted lower alkyl, optionally substituted aryl, optionally substituted lower arylalkyl, optionally substituted heterocyclyl, and optionally substituted lower heterocyclylalkyl; and R 6 and R 7 , when taken together with a common nitrogen to which they are attached, form an optionally substituted five- to seven-membered heterocyclyl ring, said optionally substituted five- to seven-membered heterocyclyl ring optionally containing at least one additional heteroatom selected from N, O, S, and P.