Patent ID: 6887863

Claim:
A compound of formula (I), or a therapeutically acceptable salt or prodrug thereof, wherein R 1 is selected from the group consisting of alkyl, aryl, arylalkyl, cycloalkyl, (cycloalkyl)alkyl, (heterocycle)alkyl, and R 5 S-(alkylene)-; wherein each group is drawn with its right-hand end being the end that is attached to the parent molecular moiety; R 3 is selected from the group consisting of hydrogen, alkyl, and arylalkyl; R 4 is selected from the group consisting of â€”NR 6 R 7 , and â€”OR 8 ; wherein each group is drawn with its left-hand end being the end that is attached to the parent molecular moiety; R 5 is selected from the group consisting of alkyl, aryl, arylalkyl, cycloalkyl, and (cycloalkyl)alkyl; R 6 and R 7 are independently selected from the group consisting of hydrogen, alkanoyl, alkenyl, alkenyloxyalkyl, alkoxyalkyl, alkoxycarbonylalkyl, alkyl, alkylsulfanylalkyl, aryl, arylalkanoyl, arylalkoxyalkyl, arylalkoxycarbonyl, arylalkyl, aryloxyalkyl, (aryl)oyl, arylsulfonyl, carboxyalkyl, cycloalkyl, (cycloalkyl)alkyl, (cycloalkyl)alkanoyl, (cycloalkyl)oyl, haloalkanoyl, haloalkyl, heterocycle, (heterocycle)alkanoyl, (heterocycle)oyl, hydroxyalkyl, a nitrogen protecting group, and â€”C(O)NR 9 R 10 ; or R 6 and R 7 together are arylalkylidene; or R 6 and R 7 , together with the nitrogen atom to which they are attached, form a heterocycle; R 8 is selected from the group consisting of hydrogen, alkanoylalkyl, alkenyl, alkoxycarbonylalkyl, alkyl, amidoalkyl, aryl, arylalkyl, arylalkoxycarbonylalkyl, (aryl)oylalkyl, carboxyalkyl, and (cycloalkyl)alkyl; and R 9 and R 10 are independently selected from the group consisting of hydrogen, alkyl and aryl.