Patent ID: 7786263

Claim:
An isolated or recombinant human hT1R2 taste receptor polypeptide which contains a sequence selected from the following: (i) a polypeptide which comprises a sequence that is identical to the transmembrane or extracellular domains of the human T1R2 polypeptide in SEQ ID NO: 21 (ii) a polypeptide which comprises a sequence that possesses at least 90% sequence identity to the transmembrane or extracellular domains of the human T1R2 polypeptide in SEQ ID NO: 21; and (iii) a polypeptide encoded by a genomic or cRNA nucleic acid sequence which hybridizes to the complement of the human T1R2 encoding nucleic acid sequence contained in SEQ ID NO: 23 under stringent hybridization conditions which consist of hybridization in 50% formamide, 5×SSC and 1% SDS, incubating at 42 degrees C., with wash in 0.2 X. SSC and 0.1% SDS at 65 degrees C., wherein said hybridization and wash steps are each carried out for at least 1 minute; and (iv) a taste receptor polypeptide or the extracellular or transmembrane domains thereof which is encoded a nucleic acid sequence having the sequence in SEQ ID NO: 23.