Patent ID: 6939680

Claim:
A method for determining whether a ligand not known to be capable of binding to a human dopamine D 1β receptor can bind to a human dopamine D 1β receptor which comprises contacting a mammalian cell transfected with and expressing the human dopamine D 1β receptor on the surface of such cell, or contacting a membrane preparation of such a cell, with the ligand under conditions permitting binding of ligands known to bind to a human dopamine D 1β receptor, detecting the presence of any of the ligand bound to the human dopamine D 1β receptor, and thereby determining whether the ligand binds to a human dopamine D 1β receptor; wherein the human dopamine D 1β receptor has the amino acid sequence shown in SEQ ID NO: 2 or an amino acid sequence identical to that encoded by the nucleic acid sequence contained in plasmid pdop-D1-GL-30 (ATCC Accession No. 40839).