Patent ID: 8597699

Claim:
A method of increasing a prostate specific antigen (PSA) doubling time in treating a patient comprising: selecting a subject with rising serum PSA; and administering to said subject a composition comprising a therapeutically effective amount of a pomegranate extract comprising a higher content of high molecular weight polyphenol compared to pomegranate juice from arils, wherein said therapeutically effective amount increases a prostate specific antigen doubling time, wherein said pomegranate extract is formed by: crushing and squeezing pomegranate solids suspended in an aqueous solution; heating said aqueous solution to between about 60° F. to about 210° F.; adding at least one enzyme to said aqueous solution; and processing said aqueous solution to separate a supernatant from residual insoluble solid materials, wherein said pomegranate extract comprises said supernatant.