Patent ID: 7696241

Claim:
A compound according to formula I: or a pharmaceutically acceptable salt thereof, wherein R 1 is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, arylalkyl, substituted arylalkyl, CO 2 R 4 , CONR 4 R 4 ′, and CH 2 OR 4 ; R 2 is independently selected from the group consisting of alkyl, substituted alkyl, OR 3 , SR 3 , halo, NHR 3 , NHCOR 4 , NHCO 2 R 4 , NHCONR 4 R 4 ′ and NHSO 2 R 4 ; R 2 ′ is independently selected from the group consisting of H, alkyl, substituted alkyl, OR 3 , SR 3 , halo, NHR 3 , NHCOR 4 , NHCO 2 R 4 , NHCONR 4 R 4 ′ and NHSO 2 R 4 ; R 2 ″ is independently selected from the group consisting of H, alkyl, substituted alkyl, OR 3 , SR 3 , halo, NHR 3 , NHCOR 4 , NHCO 2 R 4 , NHCONR 4 R 4 ′ and NHSO 2 R 4 ; R 2 ′″ is independently selected from the group consisting of H, alkyl, substituted alkyl, OR 3 , SR 3 , halo, NHR 3 , NHCOR 4 , NHCO 2 R 4 , NHCONR 4 R 4 ′ and NHSO 2 R 4 ; R 3 is independently selected from the group consisting of H, alkyl, substituted alkyl, CHF 2 , CF 3 and COR 4 ; R 4 is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; R 4 ′ is independently selected from the group consisting of H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; R 5 is independently selected from the group consisting of H, CF 3 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; R 5 ′ is independently selected from the group consisting of H, CF 3 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; X is —C(═O)—N(R 6 )— where N is attached to the carbon bearing the R 5 substituent; R 6 is selected from the group consisting of G and CH 2 G; G is aryl, wherein said aryl is mono- or polycyclic, and is optionally substituted with one or more substituents selected from the group consisting of hydrogen, halo, CN, CF 3 , OR 4 , CO 2 R 4 , NR 4 R 4 ′, CONR 4 R 4 , CH 2 OR 4 , alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, arylalkyl, substituted arylalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl; and n is 1.