Patent ID: 8309108

Claim:
A liquid aqueous formulation for the intranasal administration of apomorphine, which comprises: (a) at least about 15 mg/ml of apomorphine; and (b) a solubilising agent consisting essentially of at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer) having an average molecular mass of from about 1,065 Da to about 9,700 Da, and a general formula HO(C 2 H 4 O) a (C 3 H 6 O) b (C 2 H 4 O) a H, wherein a is from 2 to 90 and b is from 15 to 40; wherein the formulation does not contain a poloxamer of a type and in an amount resulting in a formulation too viscous to be dispersed into droplets at a temperature of 18° C. to 22° C.