Patent ID: 7550450

Claim:
A method to treat prostate cancer in a subject in need thereof, comprising administering an effective amount of a compound having the structure wherein E is —C(O)— or —CR 5 R 6 —; G is —CR 3 R 4 —; K is —CR 1 R 2 —; R 1 is —OR 11 R 2 is —H, lower alkyl or substituted lower alkyl; R 3 and R 5 independently are —H, —OH or lower alkyl; R 4 and R 6 independently are —H or lower alkyl; R 11 is —H, alkyl or substituted alkyl, —C(O)—R 12 , —S(O) 0-2 —R 12 or —C(O)—OR 12 ; R 12 is —H, alkyl or substituted alkyl; R is —OH or unsubstituted lower alkoxy; R′ is —F or unsubstituted lower alkyl; n is 0 or 1; and n′ is 0 or 1.