Patent ID: 7868196

Claim:
A process for the regioselective preparation of 1-R 1 -2-R 2 -3-acetyl-glycerol derivative of the following Formula 1 comprising the steps of: obtaining 1-R 1 -3-protecting group-glycerol of Formula 3 by introducing a protecting group to 3-position of 1-R 1 -glycerol of Formula 2; obtaining 1-R 1 -2-R 2 -3-protecting group-glycerol of Formula 4 by introducing R 2 group into 2-position of 1-R 1 -3-protecting group-glycerol of Formula 3; and carrying out the deprotection reaction and the acetylation reaction of 1-R 1 -2-R 2 -3-protecting group-glycerol of Formula 4 at the same time, wherein, the compounds of Formula 1 to 4 are racemic compounds or optically active compounds; R 1 and R 2 are fatty acid groups having 16 to 22 carbon atoms, and are different from each other; and P is trityl group or trialkylsilyl group as the protecting group, and the alkyl in trialkylsilyl group is alkyl group having 1 to 5 carbon atoms.