Patent ID: 7316908

Claim:
A method for detecting or diagnosing cancer or cellular abnormalities, said method comprising the steps of: reacting a sample of body fluid or tissue likely to contain antibodies with a protein sequence or peptide isolated from E2 early coding regions of human papillomavirus (HPV) types 16 or 18 selected from the group consisting of an E2 early coding region of HPV 18 as set forth in SEQ. ID. NO.: 1, an E2 early coding region of HPV 16 as set forth in SEQ. ID. NO.: 2, and an E2 early coding region of human HPV 16 as set forth in SEQ. ID. NO.: 3; forming an antibody-peptide complex comprising the isolated protein sequence or peptide and said sample antibodies; and detecting said antibody-peptide complex, wherein detecting the antibody-peptide complex indicates cancer or cellular abnormality, wherein said cellular abnormalities are selected from the group consisting of dysplasias, koilocytosis, hyperkeratosis, precancerous conditions, intraepithelial neoplasias, intraepithelial lesions, high-grade dysplasias, invasive cancers, malignant cancers, premalignant cells, and precancerous cells.