Patent ID: 7709452

Claim:
A method for in vivo transfer into muscle cells of at least one nucleic acid comprising administering into said cells a composition comprising: at least one nucleic acid; a Tyrode's medium comprising: 140 mM NaCl, 6 mM KCl, 3 mM CaCl 2 , 2 mM MgCl 2 , 10 mM Hepes, pH 7.4, and 10 mM gluclose; and a tetrafunctional copolymer of formula (I): where: x and y represent, independently of one another, an integer of between 1 and 500, x has a value such that said tetrafunctional copolymer of formula (I) comprises at least 30% by weight of ethylene oxide units, and said tetrafunctional copolymer is in a form of a mineral salt in which said tetrafunctional copolymer is in a cationic form.