Patent ID: 7879859

Claim:
A method for increasing insulin secretion in patient in need thereof comprising the step of administering to said patient an effective amount of a somatostatin subtype 3 receptor (SST3) antagonist of Formula 1: wherein is R 1 is selected from the group consisting of: wherein R 2 and R 3 is each independently selected from the group consisting of: (C 1-4 )alkoxy(C 1-4 )alkyl, (C 3-7 )cycloakyl(C 1-4 )alkyl, and, if R 1 is not an optionally substituted phenyl, (C 1-12 )alkyl; R 4 is selected from the group consisting of: hydrogen, (C 1-4 )alkyl, (C 1-4 )alkoxy, halogen, and trifluoromethyl; R 5 is selected from the group consisting of: hydrogen and (C 1-4 )alkyl; R 6 is (C 1-4 )alkyl; R 7 and R 8 is each independently selected from the group consisting of: hydrogen and (C 1-4 )alkyl; and X is selected from the group consisting of: hydrogen, (C 1-4 )alkoxy, (C 1-4 )alkylamino, and di(C 1-4 )alkylamino; or a pharmaceutically acceptable salt or solvate thereof.