Patent ID: 7858606

Claim:
A compound of structural formula Ia, or a pharmaceutically acceptable salt thereof, selected from the following: No. X 1 X 4 X 5 b R 1-5 II.1 CHOAc C═O CH 2 double Me II.4 CHOAc C═O C═O double Me II.5 CHOCOCH 2 Cl C═O CH 2 double Me II.6 CHOCOCH 2 Cl C═O C═O double Me II.7 CHOH C═O C═O double Me II.8 CHOH C═O C═O double Me II.9 CHOAc C═O CH 2 double Me II.11 CHOAc C═O C═O double Me II.12 CHOAc CH 2 CH 2 single Me II.13 CHOAc CH 2 CH 2 single Me II.15 CHOAc CH 2 CH 2 single Me II.16 CHOAc C═O CHOAc double Me II.17 C═O CH 2 CH 2 single Me, (R 2 :H) II.18 CHOAc CH 2 CH 2 single Me II.19 CHOH CH 2 CH 2 single Me II.20 CHOH CH 2 CH 2 single Me II.21 CHOH CH 2 CH 2 single Me II.22 CHOH CH 2 CH 2 single Me II.23 CHOAc C═O C═O double Me II.24 CHOH CH 2 CH 2 single Me II.25 CHOH CH 2 CH 2 single Me II.26 CHOH C═O C═O double Me II.27 CHOH C═O CH 2 double Me II.30 CHOH C═O CH 2 double Me II.31 CHOH C═O CH 2 double Me II.32 CHOH C═O CH 2 double Me II.35 B C═O CH 2 double Me II.36 CHOAc C═O C═O double Me II.37 CHOH C═O C═O double Me II.38 CHOH C═O C═O double Me II.40 B C═O C═O double Me II.42 B C═O CH 2 double Me II.44 B CH 2 CH 2 single Me II.46 B CH 2 CH 2 single Me II.48 B CH 2 CH 2 single Me II.49 CHOAc CH 2 CH 2 single Me II.51 B CH 2 CH 2 single Me II.52 CHOAc CH 2 CH 2 single Me II.53 CHOAc CH 2 CH 2 single Me II.54 CHOAc C═O CH 2 double Me II.55 CHOAc CH 2 CH 2 single Me II.56 CHOAc CH 2 CH 2 single Me II.57 C═O CH 2 CH 2 single Me II.58 CHOAc CH 2 CH 2 single Me No. R 7 R 9 R 10 II.1 COOH Me Me II.4 COOMe Me Me II.5 CH 2 OAc Me Me II.6 CH 2 OAc Me Me II.7 CH 2 OAc Me Me II.8 CH 2 OH Me Me II.9 COOCH 2 O—COBu t Me Me II.11 COOCH 2 OCOBu t Me Me II.12 COOH CH 2 CN II.13 COOH CH 2 COOH II.15 COOH CH 2 CH 2 OH II.16 CH 2 OAc Me Me II.17 CH 2 OAc Me Me II.18 COOH CH 2 COH II.19 COOH (20-R)—OH Me II.20 COOH (20-S)—OH Me II.21 COOH (20-R)—CH 2 OH Me II.22 COOH (20-S)—CH 2 OH Me II.23 COOCH 2 OCOMe Me Me II.24 COOCH 2 OCOBu t CH 2 COH II.25 COOCH 2 OCOMe CH 2 COH II.26 COOMe Me Me II.27 COOCH 2 OCOBu t Me Me II.30 CH 2 OAc Me Me II.31 COOMe Me Me II.32 COOCH 2 OCOMe Me Me II.35 COOMe Me Me II.36 CH 2 OH Me Me II.37 COOCH 2 OCOMe Me Me II.38 COOCH 2 OCOBu t Me Me II.40 COOMe Me Me II.42 COOH Me Me II.44 COOH CH 2 Me II.46 COOMe CH 2 Me II.48 COOCH 2 OCOMe CH 2 Me II.49 CH 2 OTs CH 2 Me II.51 HB CH 2 Me II.52 COOCOMe CH 2 COH II.53 COOCOMe CH 2 Me II.54 COF Me Me II.55 COF CH 2 Me II.56 COF CH 2 COH II.57 COF CH 2 Me II.58 COF Me Me where: B is CHOC(O)OCH 2 -2,2-dimethyl-1,3-dioxolan-4-yl Ts is OSO 2 C 6 H 4 CH 3 .