Patent ID: 7538128

Claim:
A method of inhibiting DPP-IV in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound of formula (I) wherein: Y is —S(O) m , —CH 2 —, CHF, or —CF 2 ; m is 0, 1, or 2; X is a bond, C 1 -C 5 alkyl, or —C(═O)—; the dotted line [----] in the carbocyclic ring represents an optional double bond; R 1 is CN, or a substituted or unsubstituted heteroaryl ring or substituted or unsubstituted heterocyclic ring, wherein the ring is a five-membered ring having at least one nitrogen atom; R 2 is hydrogen, nitrile (—CN), or COOH; or a tautomeric form, stereoisomer, enantiomer, diastereomer, N-oxide, or pharmaceutically acceptable salt thereof.