Patent ID: 7429462

Claim:
A kit for rapid screening of diabetes, the kit comprising: a glucose-sensing ophthalmic device and instructions for using the glucose-sensing ophthalmic device to screen for diabetes, wherein the glucose-sensing ophthalmic device comprises a testing agent composition which specifically and reversibly interacts with glucose to form a detectable optical signal which changes in a concentration-dependent manner, wherein the testing agent composition comprises a receptor having a first label associated therewith and a competitor having a second label associated therewith, wherein one of the first and second labels is a fluorescent energy donor and the other one is a fluorescent or non-fluorescent energy acceptor, wherein the ophthalmic device comprises a glucose-sensing layer-by-layer coating which is not covalently attached to the core material of the ophthalmic device, and wherein the glucose-sensing layer-by-layer coating comprises one or more layers of a vesicle with a charged surface and with the receptor and the competitor entrapped therein.