Patent ID: 7432383

Claim:
A taxane compound of formula IV C—B IV wherein B is a radical of formula V: wherein Ac is an acetyl radical, Bz is an benzyl radical, Me is a methyl radical, R 4 is an acetyl radical, or a protective group for the hydroxyl functional group, represented by GP1, and R 5 is a protective group for the hydroxyl functional group represented by GP2, wherein GP1 and GP2 are selected independently of one another from: trialkylsilyl; 2,2,2-tribromoethoxycarbonyl; 2,2,2,1-tetrachloroethoxycarbonyl; 2,2,2-trichloro-t-butoxycarbonyl; trichloromethoxycarbonyl; an acyl radical having a carbon α to the carbonyl functional group bonded to at least one oxygen atom; or a trialkylgermanyl radical; or GP1 and GP2 together form a divalent radical of formula —SiR 7 —O—SiR 8 — wherein R 7 and R 8 , independently of one another, each represent a sterically hindered alkyl radical; and wherein C is a side chain of formula IIIa or III′a: wherein Ar is an aryl radical, and R″ 2 is chosen from an aryl radical, a lower alkyl radical, a lower perhaloalkyl radical, an alkoxy radical or a linear or branched alkyl radical having at least one unsaturated bond.