Patent ID: 8906667

Claim:
An engineered Escherichia coli comprising: a. a deleted gapA (ΔgapA) gene; b. an overexpressed DNA encoding gapC (an NADP-dependent D-glyceraldehyde-3-phosphate dehydrogenase (NADP-GAPDH)); and c. an overexpressed DNA encoding: i. a β-ketothiolase, an acetoacetyl-CoA reductase and a polyhydroxybutyric acid (PHB) synthase, wherein said cell produce 5-10 fold more PHB than a control cell lacking a) and b); or ii. a cyclohexanone monooxygenase, wherein said cell produces about 1.7 fold more caprolactone than a control cell lacking a) and b), or iii. a phytoene synthase, a geranylgeranyl pyrophosphate (GGDP) synthase, and phytoene desaturase, wherein said cell produces about 2.5 fold more lycopene than a control cell lacking a) and b).