Patent ID: 7378485

Claim:
A compound having the formula: wherein: n is at least 2, each L 1 –L n is independently selected from the group consisting of hydrogen, hydroxy, (C 1 –C 4 ) alkanoyl, thymine, adenine, cytosine, guanine, and uracil; each pair of A 1 –A n and B 1 –B n is >N—C(O)—CH 2 — or >N + (R 3 )—C(O)—CH 2 —; each R 3 is independently selected from the group consisting of hydrogen, (C 1 –C 4 )alkyl, hydroxy- or alkoxy- or alkylthio-substituted (C 1 –C 4 )alkyl, hydroxy, alkoxy, alkylthio and amino; each of T 1 –T n is CR 6 R 7 , CHR 6 CHR 7 or CR 6 R 7 CH 2 , where R 6 and R 7 are independently selected from the group consisting of hydrogen, (C 2 –C 6 )alkyl, aryl, aralkyl, heteroaryl, hydroxy, (C 1 –C 6 )alkoxy, (C 1 –C 6 )alkylthio, NR 3 R 4 and SR 5 , where R 3 and R 4 are as defined above, and R 5 is hydrogen, (C 1 –C 6 )alkyl, hydroxy-, alkoxy-, or alkylthio- substituted (C 1 –C 6 )alkyl, or R 6 and R 7 taken together complete an alicyclic or heterocyclic system; each of D 1 –D n is CR 6 R 7 , CH 2 CR 6 R 7 or CHR 6 CHR 7 , where R 6 and R 7 are as defined above; each of G 1 –G n−1 is −NR 3 CO—, —NR 3 CS—, —NR 3 SO— or —NR 3 SO 2 —, in either orientation, where R 3 is as defined above; Q is —CO 2 H, —CONR′R″, —SO 3 H or —SO 2 NR′R″ or an activated derivative of —CO 2 H or —SO 3 H; and I is —NHR′″R″″ or —NR′″C(O)R″″, where R′, R″, R′″ and R″″ are independently selected from the group consisting of hydrogen, alkyl, amino protecting groups, reporter ligands, chelators, peptides, proteins, carbohydrates, lipids, steroids, and LysNH 2 .