Patent ID: 8399485

Claim:
A compound represented by formula I or a pharmaceutically acceptable salt thereof wherein R 1 represents a 6-10 membered aryl group or a 5-10 membered heteroaryl group containing one or two rings, at least one nitrogen atom 0-2 additional nitrogen atoms, and 0-1 oxygen or sulfur atoms, said 6-10 membered aryl or 5-10 membered heteroaryl group being optionally substituted with 1-3 halo groups, wherein said 6-10 membered aryl or 5-10 membered heteroaryl group is substituted with 1-2 members selected from the group consisting of: (1) C 1-6 alkyl or C 3-6 cycloalkyl, substituted with 1-2 members selected from the group consisting of: i) S(O) x C 1-3 alkyl, wherein x is 0, 1 or 2 and the alkyl portion is optionally substituted with 1-3 halo atoms; and ii) C(O)NR d R e or NR d C(O)R e , wherein R d is selected from H and C 1-3 alkyl and R e is selected from H, C 1-6 alkyl, C 3-6 cycloalkyl, a 5-6 membered Heteroaryl group and phenyl; (2) S(O) x C 1-6 alkyl, and SO 2 NR d R e wherein the C 1-6 alkyl group is optionally substituted with 1-3 halo groups, wherein x is 0, 1 or 2 and wherein R d and R e are as defined above; and (3 ) C(O)NR d R e or NR d (O)R e wherein R d and R e are as defined above; and R 2 is selected from the group consisting of C 1-8 alkyl, C 3-6 cycloalkyl, OC 1-8 alkyl and O-Phenyl, the phenyl portion of which being optionally substituted with 1-3 halo groups and 0-1 C 1-3 alkyl, haloalkyl, alkoxy or haloalkoxy groups, and each of said C 1-8 alkyl, C 3-6 cycloalkyl and OC 1-8 alkyl being optionally substituted with 1-3 halo proups, and 0-1 members selected from the group consisting of OH, oxo CN, OC 1-6 alkyl, haloC 1-6 alkoxy, pyridyl, C(O)C 1-3 alkyl phenyl, and C(O)phenyl, said phenyl, pyridyl and the phenyl portion of C(O)phenyl being optionally substituted with 1-3 halo atoms, and 1-2 C 1-6 alkyl or OC 1-6 alkyl groups.