Patent Description:
A fluid delivery device is a medical appliance which can achieve patient disease treatment by continuously infusing a drug into a patient. The fluid delivery device is widely used in the treatment of diabetes. The fluid delivery device continuously infuses insulin into a subcutaneous tissue of a patient based on a dosage required by the patient, so as to simulate the secretion function of the pancreas and to stabilize blood glucose of the patient. The fluid is usually stored in a pump base, and a conventional fluid delivery device usually infuses the fluid into a patient via a catheter/tube connected to the pump base. The catheter, when it is used, is an obstruction for the patient's activities. In order to overcome the above-mentioned shortcomings of the conventional fluid delivery device, a tubeless fluid delivery device has been developed, which has a pump base stuck to the patient's body by a medical adhesive tape. However, in the above-mentioned tubeless fluid delivery device, the pump base is integrated in a box with a controller, and the box is a disposable medical appliance. Such a tubeless fluid delivery device has high costs. Furthermore, the existing fluid delivery device also has some shortages such as complicated operation, large size, large mass, and inconvenient wearing.

When diabetes patients are being treated by insulin infusion, they usually need to wear two sets of components, one is a glucose probe and another is an insulin delivery system. A glucose sensor of the glucose probe and an indwelling cannula of the insulin delivery system are required to be inserted into and implanted into the subcutaneous tissue of the patients. Considering the comfort level of the patients when they are wearing these components, the two components are both made of slender and soft medical polymer materials. Because of the special natures of the materials and the shapes of the two components, they both need to be put into the subcutaneous tissue of the patients with a help of a puncture needle with a certain rigidity to puncture the skin of the patients. Thereafter, the needle is pulled out, leaving the two components in the subcutaneous tissue. The glucose sensor and the indwelling cannula have similar processes of puncture and indwelling, and similar mechanical structures for realizing these processes. Moreover, the glucose sensor and the indwelling cannula are also the same in aspects such as action area on body, disposable using, aseptic production, etc. Therefore, a concept of "two in one" is introduced in the present disclosure, leading to a micro system which integrates the glucose probe and the insulin delivery system in one body and has effects of both glucose monitoring and insulin administration.

<CIT> discloses a fluid dispensing device that includes at least one reservoir to hold the therapeutic fluid, at least one other unit requiring communication with ambient air, at least partly, to operate, and at least one housing defining an interior to retain the at least one reservoir and the at least one other unit. <CIT> discloses a skin adherable device for delivering therapeutic fluid into a body of a patient. <CIT> discloses a delivery system for delivering fluidic media to a user having a second housing portion configured to be selectively operatively engaged with and disengaged from a first housing portion, the first housing portion and the second housing portion configured to be slidable relative to each other to operatively engage each other; and a fluid connector supported by one the housing portions in a position to engage a reservoir supported by an other of the housing portions in a case. <CIT> discloses a method and a device for a delivery of a chemical substance to the body of the patient are provided. The device includes an infusion catheter configured to be inserted into a tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused
region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient. <CIT> discloses a dual insertion set for supplying a fluid to the body of a patient and for monitoring a body characteristic of the patient. <CIT> discloses a catheter head including a cannula housing, a needle holder connectable to the cannula housing and a guide sleeve associated with the needle holder for positioning and guiding a connecting needle, and for being narrowly slide-guided over a portion of said cannula housing.

Regarding the above-mentioned shortcomings of the prior art, an object of the present disclosure is to provide a tubeless fluid delivery device for solving the problems of complicated operation, large size and high costs in the existing fluid delivery device.

In order to achieve the above-mentioned purposes and other related purposes, the present disclosure provides a tubeless fluid delivery device, including: a controller, including a first housing which has a first built-in circuit, where the first housing is provided with a first engagement part, and a first insertion part electrically connected to the first built-in circuit; and a pump base combined with the controller, which includes a second housing having a second built-in circuit, a reservoir, a piston, a push rod, a driving member and a battery, where the second housing is provided with a second engagement part correspondingly engaged with the first engagement part, and a second insertion part electrically connected to the second built-in circuit, where the second insertion part is correspondingly inserted in the first insertion part to realize electrical connection between the first built-in circuit and the second built-in circuit.

Optionally, the first engagement part is a clamping hole or a clamping slot. The second engagement part is a clamping hook corresponding to the clamping hole or the clamping slot, and the clamping hook is connected to a clamping hook handle which is used to disengage the clamping hook from the clamping hole or the clamping slot when needed. Or optionally, the second engagement part is a clamping hook corresponding to the clamping hole or the clamping slot, and the first housing is provided with a button used to disengage the clamping hook from the clamping hole or the clamping slot when needed.

The first insertion part is a sealed socket. The sealed socket is provided with a groove in which a connector electrically connected to the first built-in circuit is provided, and an O-shaped sealing ring is set on a surface on which the connector is attached with the sealed socket. The second insertion part is a plug which includes a plug body circumferentially set with an O-shaped sealing ring, and a bolt embedded in the plug body. When the plug is inserted into the sealed socket, the bolt is inserted into the connector and electrically connected to the connector, and the O-shaped sealing ring on the plug body and the sealed socket fit tightly to achieve waterproof sealing.

Optionally, a main frame used as a supporter for the structure of the pump body and a supporter for the second built-in circuit is embedded in the pump body, and the second built-in circuit set on the main frame is a 3D printed circuit which is electrically connected to the second insertion part.

Optionally, a first combination of functions realized by signal lines on the second insertion part includes a position detection, a left in place detection, a right in place detection, a battery positive electrode, a blockage detection, a left side drive, a right side drive and a battery negative electrode; a second combination of functions realized by signal lines on the second insertion part includes a reference electrode, a buzz left in place detection, a public right in place detection, a battery positive electrode, a working electrode, a left side drive, a right side drive and a battery negative electrode; or a third combination of functions realized by signal lines on the second insertion part includes a position detection, a left in place detection, a right in place detection, a battery positive electrode, a buzz positive electrode, a left side drive, a right side drive and a battery negative electrode. Correspondingly, if the first combination or the second combination is used, a ground wire of the second insertion part is connected to a common port of the position detection, a common port of the left in place detection, a common port of the right in place detection, a common port of the blockage detection, and the battery negative electrode; if the third combination is used, the ground wire of the second insertion part is connected to the common port of the position detection, the common port of the left in place detection, the common port of the right in place detection, the common port of the blockage detection, the buzz positive electrode, and the battery negative electrode.

Optionally, the battery of the tubeless fluid delivery device is a button battery.

Optionally, the first built-in circuit of the controller includes a control circuit and a program processing module. The first housing is provided with a first buzzer chamber in which a first buzzer is disposed, and the first buzzer is connected to the first built-in circuit of the controller via a wire. Or the second housing is provided with a second buzzer chamber in which a second buzzer is disposed, and the second buzzer is connected to the second built-in circuit of the controller via a contact.

Optionally, the pump base further includes a subcutaneous cannula installation device having a steel needle, a steel needle bed, a spring and a toggle switch. The pump base further includes an indwelling cannula of the steel needle, and the indwelling cannula is implanted subcutaneously via the aid of the steel needle. If the steel needle is a hollow needle, the indwelling cannula covers the hollow needle; or if the steel needle is a groove steel needle, the indwelling cannula is set in the groove of the groove steel needle. A glucose sensor is set on the outer surface of the indwelling cannula.

Optionally, the pump base further includes a fluid outlet which is provided with an delivery fluid plug having a plastic base, a silica gel plug and a polymer film. The delivery fluid plug is connected to the second housing via a fastener, and the delivery fluid plug is detachable from the pump base when the plastic base is lifted.

Optionally, a medical adhesive tape configured to stick to the skin of a patient is fixed on the pump base.

Optionally, the tubeless fluid delivery device further includes a skin heating device configured to heat the skin at which the fluid is infused.

Optionally, the pump base further includes an identity recognition tag which may be a near field communication (NFC) tag, a radio frequency identification (RFID) tag or an identity recognition chip.

As mentioned above, the tubeless fluid delivery device in the present disclosure uses separable structure to reduce costs. Specifically, it defines the active controller as a main control machine, and defines the pump base as passive consumables. That is, the active part are taken as a reusable part, while the passive part is deemed as disposable. The two parts are packed separately and can be used together to complete the treatment of a patient. Specifically, when the tubeless fluid delivery device is used, the patient assembles the controller and pump base together to form the delivery device, sticks the tubeless fluid delivery device to his/her skin and then uses it as normal. When the fluid stored in the pump base runs out, or the device breaks down, the controller will remind the user, by using the buzzer, to remove and discard the pump base, and to install a new pump base and stick the tubeless fluid delivery device to the skin for sequential using.

The embodiments of the present disclosure are described in the following through specific examples, and those skilled in the art can easily understand other advantages and effects of the present disclosure according to the content disclosed in the specification.

Referring to <FIG>, it should be noted that, structures, scales and sizes shown in the drawings are only used to illustrate the contents disclosed in the specification, for being understood and read by those skilled in the art, instead of limiting implementation conditions of the present disclosure. Any modification in structure, change in scale, or adjustment in size should fall within the scope of the technical solution disclosed by the present disclosure without influencing the generated efficacy and achieved objective of the present disclosure. Meanwhile, some words such as "upper", "lower", "left", "right", "middle", and "a" quoted in the specification are only used for clarity of the illustration instead of limiting the implementation scope of the present disclosure, and any change or adjustment of relative relationships should be considered as falling within the scope of implementation of the present disclosure without essentially changing the technical content.

The present disclosure provides a tubeless fluid delivery device, which is configured to achieve patient disease treatment by continuously delivering a fluid into the patient. In practical application, the fluid delivery device can be widely used in treating of diabetes. The fluid delivery device continuously delivers insulin into a subcutaneous tissue of a patient based on a dosage required by the patient, so as to simulate the secretion function of the pancreas and stabilize blood glucose of the patient. The tubeless fluid delivery device in the present disclosure includes a controller and a pump base. The bump base is combined with the controller. Specifically, the pump base is mechanically combined with the controller by engaging a first engagement part and a second engagement part, and is electrically connected to the controller by connecting a first insertion part to a second insertion part.

The controller includes a first housing having a first built-in circuit, where the first housing is provided with a first engagement part and a first insertion part electrically connected to the first built-in circuit.

The pump base includes a second housing having a second built-in circuit, a reservoir, a piston, a push rod, a driving member and a battery, where the second housing is provided with a second engagement part correspondingly engaged with the first engagement part and a second insertion part electrically connected to the second built-in circuit, where the second insertion part is correspondingly inserted in the first insertion part to realize electrical connection between the first built-in circuit and the second built-in circuit.

Referring to <FIG>, a tubeless fluid delivery device according to one embodiment of the present disclosure is schematically illustrated. As shown in <FIG>, in the embodiment, the first engagement part <NUM> is a clamping hole. A flange structure <NUM> is set inside the clamping hole, but it is not limited to this. The first engagement part <NUM> can also be a clamping slot or other structures that can be engaged with a clamping hook. Correspondingly, the second engagement part <NUM> is a clamping hook corresponding to the clamping hole, and the clamping hook is connected to a clamping hook handle <NUM>. Referring to <FIG> schematically illustrates an operation structure according to one embodiment of the present disclosure. <FIG> illustrates an enlarged view in section A of <FIG>. As shown in <FIG>, in some embodiments, the clamping hook can be disengaged from the clamping hole by controlling the clamping hook handle <NUM>. Specifically, there is a gap between the inner side of the clamping hook handle <NUM> and the bottom shell of the pump base <NUM>. When the clamping hook handle <NUM> is pressed, the clamping hook handle <NUM> pushed the clamping hook and disengages it from the clamping hole.

In some embodiments, Referring to <FIG> schematically illustrates a first insertion part according to one embodiment of the present disclosure. <FIG> illustrates an enlarged view in section B of <FIG>. As shown in <FIG>, the first insertion part <NUM> is a sealed socket. Specifically, the sealed socket is provided with a groove <NUM>, and the groove <NUM> is provided with a connector <NUM> configured to be electrically connected to the first built-in circuit, where an O-shaped sealing ring <NUM> is set on a surface on which the connector <NUM> is attached with the sealed socket.

Correspondingly, the second insertion part is a plug. Referring to <FIG>, a second insertion part according to one embodiment of the present disclosure is schematically illustrated. As shown in <FIG>, the plug includes a plug body <NUM> circumferentially set with an O-shaped sealing ring <NUM>, and a bolt <NUM> embedded in the plug body <NUM>. The bolt <NUM> is a wedge structure, which is convenient for the installation of the pump base. When the plug is inserted into the sealed socket, the bolt is inserted into the connector <NUM> and realizes electrical connection to the connector, where the O-shaped sealing ring <NUM> on the plug body and the sealed socket fit tightly to achieve waterproof sealing.

In one embodiment, as shown in <FIG>, the second housing of the pump base <NUM> includes a bottom shell of the pump base <NUM> and a top shell of the pump base <NUM>. The bottom shell of the pump base <NUM> is provided with two clamping hooks and clamping hook handles <NUM>, and the first housing of the controller <NUM> is provided with two corresponding clamping holes and the sealed socket. The connector <NUM> is set inside the sealed socket. When the pump base <NUM> and the controller <NUM> are combined, the clamping hooks are inserted into the clamping holes, and the plug is inserted into the sealed socket. The clamping hooks slide into the clamping holes guided by their front inclined plates and thus are engaged with the flange structures <NUM> of the clamping holes. Therefore, the pump base <NUM> and the controller <NUM> are tightly combined together. Two O-shaped sealing rings <NUM> on the plug body and the sealed socket are squeezed together to form a waterproof structure. There is a gap between the inner side of the clamping hook handle <NUM> and the bottom shell of the pump base <NUM>. When the clamping hook handle <NUM> is pressed inwardly, the clamping hook handle <NUM> disengages the pump base <NUM> from the controller <NUM>. From the above description, the pump base <NUM> and the controller <NUM> are combined by engaging the clamping hooks and the clamping holes, and realize electrical connection by inserting the plug into the sealed socket.

Referring to <FIG> and <FIG>, <FIG> schematically illustrates an exploded view of a first buzzer chamber and a first buzzer according to one embodiment of the present disclosure. <FIG> schematically illustrates a combined view of a first buzzer chamber and a first buzzer according to one embodiment of the present disclosure. As shown in <FIG> and <FIG>, the first housing is provided with a first buzzer chamber <NUM>, in which a first buzzer <NUM> is disposed, and the first buzzer <NUM> is connected to the first built-in circuit of the controller <NUM> via a wire (not shown). When the fluid stored in the pump base <NUM> runs out, or the device breaks down, the controller <NUM> will remind the user by using the first buzzer <NUM> to remove and discard the pump base <NUM>, and to install a new pump base <NUM> and stick the tubeless fluid delivery device to the skin for sequential using.

Referring to <FIG> and <FIG>, an inner structure of the second housing according to one embodiment of the present disclosure is schematically illustrated. As shown in <FIG> and <FIG>, a main frame <NUM> configured to be used as a structure supporter for the pump base and a supporter for the second built-in circuit is embedded in the pump body <NUM>. The second built-in circuit set on the main frame <NUM> is a 3D printed circuit (not shown), which is electrically connected to the second insertion part <NUM>. That is, the main frame <NUM> configured to be used as a structure supporter for the pump base and a supporter for the second built-in circuit is embedded in the pump body <NUM>, and the main frame <NUM> is provide with a 3D printed circuit, which is electrically connected to the second insertion part <NUM>, so that signal transmission from the connector <NUM> in the sealed socket of the controller <NUM> to the 3D printed circuit is realized. The second insertion part <NUM> is a plug which includes a plurality of signal lines. A first combination of function realized by the signal lines includes a position detection, a left in place detection, a right in place detection, a battery positive electrode, a blockage detection, a left side drive, a right side drive and a battery negative electrode. It should be noted that, in the figures according to the embodiment of the present disclosure, the signal lines is not given reference signs. That is, the arrangement of the signal lines is not limited to the above, other adjusted arrangements, including the signal lines according to the embodiment, also belong to the protection range of the present disclosure.

In one embodiment, as shown in <FIG> and <FIG>, the main frame <NUM> configured to be used as a structure supporter for the pump base and the second built-in circuit supporter is embedded in the pump body <NUM>. The main frame <NUM> has two important roles, one is to be used as a inserting supporter and a fixing supporter for all components of the pump base <NUM>, the other is to support the 3D printed circuit through which the active controller <NUM> can control the pump base <NUM>. The main frame <NUM> is manufactured by materials which can meet the temperature requirements of manual welding or even the high temperature welding of Surface Mount Technology (SMT). To prevent the interference between the shell of the pump base and the main frame <NUM> in the installing process, the main frame <NUM> is configured as a wedge structure. In the embodiment, the plug of the main frame <NUM> is configured as a bolt of the second insertion part <NUM>. The signal lines are distributed on both sides of the plug of the main frame <NUM>. The signal lines realize functions of position detection, left in place detection, right in place detection, battery positive electrode, blockage detection, left side drive, right left drive and battery negative electrode. Optionally, the signal lines near the side of the delivery fluid inlet successively realize function of blockage detection, left side drive, right left drive and battery negative electrode from top to bottom. And the signal lines in the other side successively realize function of position detection, left in place detection, right in place detection, and battery positive electrode.

The distribution of the main frame <NUM> and the ground wire in the pump base <NUM> are illustrated in <FIG> and <FIG>. In one embodiment, the pump base <NUM> and the controller <NUM> are separated. The battery is a single button battery <NUM> and is set in battery slot <NUM> set on the main frame <NUM>. The button battery <NUM> is fixed by the main frame <NUM> and a battery positive connector <NUM>. The battery positive connector <NUM>, a battery negative spring <NUM> and the 3D printed circuit of the main frame <NUM> are coupled. The ground wire <NUM> is connected to the common ports of position detection, left in place detection, right in place detection and blockage detection, and connected to the battery negative electrode.

In <FIG> and <FIG>, the reference sign <NUM> indicates a slot for setting reservoir.

Referring to <FIG>, an operation structure according to another embodiment of the present disclosure is schematically illustrated. In the embodiment, the first housing of the controller <NUM> is provided with a button <NUM> configured to disengage the clamping hook from the clamping hole. Referring to <FIG>, in the embodiment, the pump base <NUM> and the controller <NUM> are combined by the clamping hook set on the bottom shell of the pump base <NUM>, and the controller <NUM> is provided with the button <NUM> configured to disengage the pump base <NUM> from the controller <NUM>. The bottom shell of the pump base <NUM> is provided with two clamping hooks, and the controller <NUM> is provided with two buttons and the sealed socket in which the connector <NUM> is set. The top shell of the pump base <NUM> is provided with a plug. The plug of the main frame <NUM> penetrates through the gap of the plug set in the top shell of the pump base. The plug set in the top shell of the pump base and the plug of the main frame together form the plug of the pump base <NUM>. When the pump base <NUM> and the controller <NUM> are combined, the clamping hooks are inserted into the clamping holes, and the plug of the pump base is inserted into the sealed socket. The clamping hooks slide, guided by their front inclined plates, into the clamping holes, and thus being engaged with the flange structures <NUM> of the clamping holes. Therefore, the pump base <NUM> and the controller <NUM> are tightly combined. Two O-shaped sealing rings on the plug of the top shell of the pump base and the sealed socket also fit tightly. When the button is pressed, the pump base <NUM> is disengaged from the controller <NUM>. The groove configured to arrange the connector <NUM> is set in the sealed socket of the controller <NUM>. When the plug of the pump base is inserted into the sealed socket, the plug of the main frame is inserted into the connector <NUM>, realizing electrical connection between the connector <NUM> and the pump base <NUM>. An O-shaped sealing ring is set on a surface on which the connector <NUM> is attached with the shell of the controller <NUM>. The O-shaped sealing rings on the plug of the top shell of the pump base and the O-shaped sealing ring in the sealed socket achieve sealing effect and waterproof, when the controller <NUM> is combined with the pump base <NUM>.

Referring to <FIG> and <FIG>, <FIG> schematically illustrates an exploded view of a buzzer set in the second housing according to one embodiment of the present disclosure, and <FIG> schematically illustrates a buzzer set in the second housing according to one embodiment of the present disclosure. As shown in <FIG> and <FIG>, the second housing is provided with a second buzzer chamber <NUM>, in which a second buzzer <NUM> is disposed. And the second buzzer <NUM> is connected to the 3D printed circuit of the pump base via a contact <NUM>. When the fluid stored in the pump base <NUM> runs out, or the device breaks down, the controller <NUM> will remind the user by using the second buzzer <NUM> to remove and discard the pump base <NUM>, and to install a new pump base <NUM> and stick the tubeless fluid delivery device to the skin for sequential using.

To prevent interference between the shell of the pump base <NUM> and the main frame <NUM> in the installing process, the plug of the main frame <NUM> is a wedge. As shown in <FIG> and <FIG>, the signal lines are distributed on both sides of the plug of the main frame <NUM>, which realize functions of position detection, left in place detection, right in place detection, battery positive electrode, buzz positive, left side drive, right side drive and battery negative electrode. Optionally, the signal lines near the side of the delivery fluid inlet successively realize functions of buzz positive, left side drive, right left drive and battery negative electrode from top to bottom. The signal lines in the other side successively realize functions of position detection, left in place detection, right in place detection, and battery positive electrode.

Referring to <FIG>, an internal view of a second housing according to another embodiment of the present disclosure is schematically illustrated. The distribution of the main frame <NUM> embedded in the pump base <NUM> and the ground wire is illustrated in <FIG>. In the embodiment, the battery is configured as two button batteries <NUM> which are set in a battery slot <NUM> set on the main frame <NUM> and are connected via a conduction connector <NUM>. And the two batteries supply power through the ground wire <NUM> on the main frame <NUM> and the battery positive electrode <NUM>. The ground wire is connected to the common ports of position detection, left in place detection, right in place detection and blockage detection, and connected to a buzz positive electrode and the battery negative electrode.

Referring to <FIG>, <FIG> schematically illustrates a subcutaneous cannula installation device according to one embodiment of the present disclosure, <FIG> schematically illustrates a sectional view along A-A direction of <FIG>, and <FIG> schematically illustrates a steel needle, an indwelling cannula and a glucose sensor according to one embodiment of the present disclosure. As shown in <FIG>, the pump base <NUM> further includes a subcutaneous cannula installation device <NUM> having a steel needle <NUM>, a steel needle bed <NUM>, a spring <NUM> and a toggle switch <NUM>. The pump base <NUM> further includes an indwelling cannula <NUM> of the steel needle <NUM>, and the indwelling cannula <NUM> is implanted subcutaneously via the aid of the steel needle <NUM>. In one embodiment, the steel needle is a hollow needle, and the indwelling cannula covers the hollow needle. In one embodiment, the steel needle is a groove steel needle, and the indwelling cannula is set in the groove of the groove steel needle. Referring to <FIG>, a glucose sensor <NUM> is set on the outer surface of the indwelling cannula.

In the embodiment, the steel needle is a hollow needle or a groove steel needle. When the steel needle is a hollow needle, the indwelling cannula covers the hollow needle, which is shown in <FIG>. When the steel needle is a groove steel needle, the indwelling cannula is set in the groove of the groove steel needle, which is not shown.

In one embodiment, as shown in <FIG>, in the tubeless fluid delivery device, a fluid stored in a reservoir (not shown, the reservoir is set in the slot for reservoir) in the pump base <NUM> is infused into a patient's body through the indwelling cannula or the steel needle embedded subcutaneously. The indwelling cannula and/or the steel needle are both embedded subcutaneously via the subcutaneous cannula installation device <NUM>. From a structural standpoint, the subcutaneous cannula installation device <NUM> includes the steel needle <NUM>, the steel needle bed <NUM>, the spring <NUM> and the toggle switch <NUM>. From a functional standpoint, the subcutaneous cannula installation device <NUM> includes an ejection mechanism, a return needle device, or a combination thereof, where the ejection mechanism may be automatic or a manual, and the return needle device may be automatic or a manual. When the steel needle is implanted, the subcutaneous cannula installation device <NUM> directly punctures the steel needle into the skin of the patient via the ejection mechanism. When the indwelling cannula is implanted, the subcutaneous cannula installation device <NUM> uses the steel needle to puncture the skin of the patient by using the ejection mechanism, and then pulls out the steel needle by using the return needle device. The subcutaneous cannula installation device <NUM> may be set inside the pump base or be set out of the pump base. The inner structure of the subcutaneous cannula installation device <NUM> embedded in the pump base is shown in <FIG> and <FIG>. Here is an example of implanting the indwelling cannula into the skin of a patient, while the steel needle is a hollow needle, and the steel needle is set in the indwelling cannula. Initially, the steel needle and the indwelling cannula are both located in the steel needle bed. When the steel needle bed is pushed down, the steel needle punctures the skin of the patient and implants the indwelling cannula into the skin of patient. When the steel needle bed is pushed to the bottom, the toggle switch limit the steel needle bed, and the spring is in the compression state. Thereafter, the toggle switch is touched to release the spring, so as to push the steel needle base to move upward. As such, the steel needle is pulled out from the body of the patient.

Because the glucose sensor and the indwelling cannula are the same in aspects such as action area on body, disposable using, aseptic production, etc., the glucose sensor may be integrated on an outer surface of the indwelling cannula. As shown in <FIG>, the indwelling cannula and the glucose sensor are simultaneously implanted subcutaneously.

In the tubeless fluid delivery device of the present disclosure, if the glucose sensor is integrated on the outer surface of the indwelling cannula, the signal lines located on both sides of the plug of the main frame <NUM> realize functions of a reference electrode, a buzz left in place detection, a public right in place detection, a battery positive electrode, a working electrode, a left side drive, a right side drive and a battery negative electrode. Optionally, the signal lines near the side of the delivery fluid inlet successively realize functions of a working electrode, a left side drive, a right left drive and a battery negative electrode from top to bottom, and the signal lines in the other side successively realize functions of a reference electrode, a buzz left in place detection, a public right in place detection and a battery positive electrode. The ground wire is connected to the common ports of position detection, left in place detection, right in place detection and blockage detection, and connected to a battery negative electrode.

Referring to <FIG> and <FIG>, <FIG> schematically illustrates an exploded view of a delivery fluid plug according to one embodiment of the present disclosure, and <FIG> schematically illustrates a delivery fluid plug according to one embodiment of the present disclosure. As shown in <FIG> and <FIG>, the pump base <NUM> further includes a fluid outlet <NUM>, which is provided with a delivery fluid plug <NUM> having a plastic base <NUM>, a silica gel plug <NUM> and a polymer film <NUM>. The delivery fluid plug <NUM> is connected to the second housing via a fastener (an engagement structure having a clamping hook <NUM> and a clamping hole <NUM> shown in <FIG>). The delivery fluid plug <NUM> can be disengaged from the pump base <NUM>, when the plastic base <NUM> is lifted. In one embodiment, when the tubeless fluid delivery device in the present disclosure infuses the fluid into the body of the patient, a syringe is needed to infuse the fluid into the pump base through the delivery fluid inlet. To prevent the fluid leakage in the delivery process, a delivery fluid plug is set in the fluid outlet of the pump base. As shown in <FIG>, the delivery fluid plug <NUM> includes the plastic base <NUM>, the silica gel plug <NUM> and the polymer film <NUM>. The delivery fluid plug <NUM> is connected to the bottom shell of the pump base by a clamping hook of the plastic base <NUM>, and the delivery fluid plug prevents leakage of the fluid around. The polymer film <NUM> realizes a ventilation function and a waterproof function. The delivery fluid plug <NUM> can be disengaged from the pump base, when the plastic base is lifted. The reference sign <NUM> in <FIG> and <FIG> indicates the delivery fluid inlet.

Referring to <FIG>, a medical adhesive tape, a skin heating device and an identity recognition tag according to one embodiment of the present disclosure are schematically illustrated. As shown in <FIG>, the pump base <NUM> includes a medical adhesive tape <NUM> configured to be stuck to the skin of the patient. The tubeless fluid delivery device further includes a skin heating device <NUM> configured to heat the skin at which the fluid is infused. The pump base further includes an identity recognition tag <NUM>, which may be a near field communication (NFC) tag, a radio frequency identification (RFID) tag or an identity recognition chip.

In some embodiments, the tubeless fluid delivery device is stuck to the skin of the patient by the medical adhesive tape <NUM>. The pump base <NUM> is bigger and heavier than the controller <NUM>. It only needs to pre-fix the medical adhesive tape <NUM> on the bottom shell of the pump base, such that the tubeless fluid delivery device can be stably attached to the patient. When the pump base <NUM> is removed and replaced, the medical adhesive tape <NUM> is also removed and replaced together. The position at which the new pump base <NUM> is stuck may be changed, so as to avoid the physical discomfort of the patient caused by sticking the medical adhesive tape at the same position for a long time and repeated punctures. The skin heating device <NUM>, the identity recognition tag <NUM>, or a combination thereof, is set between the medical adhesive tape and the bottom shell of the pump base. When the patient is infused with the insulin, the skin heating device <NUM> may reduce the delay of the insulin peak action time. The identity recognition tag <NUM> is configured to store the personalized information of the pump base <NUM> and recognize identity, which may be a near field communication (NFC) tag, a radio frequency identification (RFID) tag or an identity recognition chip.

In summary, the tubeless fluid delivery device in the present disclosure uses separable structure to reduce costs. It uses the active controller as a main control machine, and uses the pump base as passive consumables. That is, the active part can be reused, while the passive part is disposable. The two parts are packed separately and can be used together to treat the patient. Specifically, when a tubeless fluid delivery device is needed, the patient assembles the controller and pump base together to form the delivery device, sticks the formed tubeless fluid delivery device to his/her skin and then uses it as normal. When the fluid stored in the pump base runs out, or the device breaks down, the controller will remind the user, by using the buzzer, to remove and discard the pump base. The controller further reminds the user to install a new pump base to the controller to form a new tubeless fluid delivery device, and stick the tubeless fluid delivery device to the skin for sequential using. The present disclosure overcomes the various shortcomings of the current technology and has high industrial utilization values.

Claim 1:
A tubeless fluid delivery device comprising:
a controller (<NUM>), comprising a first housing which has a first built-in circuit, wherein the first housing is provided with a first engagement part (<NUM>) and a first insertion part (<NUM>) electrically connected to the first built-in circuit; and
a pump base (<NUM>) combined with the controller (<NUM>), which comprises a second housing having a second built-in circuit, a reservoir, a piston, a push rod, a driving member and a battery, wherein the second housing is provided with a second engagement part (<NUM>) correspondingly engaged with the first engagement part (<NUM>) and a second insertion part (<NUM>) electrically connected to the second built-in circuit, wherein the second insertion part (<NUM>) is correspondingly inserted in the first insertion part (<NUM>) to realize electrical connection between the first built-in circuit and the second built-in circuit;
characterized in that
the second engagement part (<NUM>) is connected to a clamping hook handle (<NUM>), a gap is formed between an inner side of the clamping hook handle (<NUM>) and a bottom shell of the pump base (<NUM>), wherein when the clamping hook handle (<NUM>) is pressed, the clamping hook handle (<NUM>) pushes the second engagement part (<NUM>) and disengages it from the first engagement part (<NUM>);
in that the first insertion part (<NUM>) is a sealed socket, the sealed socket is provided with a groove (<NUM>) in which a connector (<NUM>) configured to be electrically connected to the first built-in circuit is disposed, wherein an O-shaped sealing ring (<NUM>) is set on a surface on which the connector (<NUM>) is attached with the sealed socket; and
in that the second insertion part (<NUM>) is a plug which comprises a plug body (<NUM>) circumferentially set with an O-shaped sealing ring (<NUM>) and a bolt (<NUM>) embedded in the plug body (<NUM>);
wherein the bolt (<NUM>) is a wedge structure;
and wherein when the plug is inserted into the sealed socket, the bolt (<NUM>) is inserted into the connector (<NUM>) and is electrically connected to the connector (<NUM>), wherein the O-shaped sealing ring (<NUM>) on the plug body (<NUM>) and the sealed socket fit tightly to achieve water proof sealing.