Patent Description:
Silicone elastomers are included in cosmetic compositions to improve sensorial properties. The term silicone elastomer means cross-linked silicone polymer which swell significantly in a solvent forming a space-filling material which behaves as a visco-elastic soft solid. Generally, the silicone elastomers are dosed in the form of a blend of the elastomer with a cyclic or linear silicone solvent.

To provide sunscreen compositions having high sun protection factor (SPF) and UV-A protection factor (UVAPF), one way is to incorporate more and more amount of UV-A and UV-B sunscreens. However, it is difficult to formulate stable compositions containing such high amount of sunscreens that also comprise silicone elastomers, due to poor compatibility between the two. The structural integrity of the blend comprising the silicone elastomer and the solvent is likely to collapse which may render ineffective the elastomer which as a consequence may no longer provide desired sensorial properties.

<CIT>) discloses cosmetic compositions that comprise blend of a silicone elastomer and a solvent, where the solvent is a volatile silicone oil selected from octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, blends of methyl trimethicone and dimethicone and mixtures thereof and wherein the silicone elastomer has the chemical structure of formula (I). It is disclosed that the composition may additionally comprise an organic sunscreen.

The present inventors have unexpectedly found that cosmetic compositions comprising an organic sunscreen and a blend comprising a silicone elastomer gel having a particular structure as defined herein and a non-silicone solvent, are stable for prolonged period. This observation provides a reliable method to formulate cosmetic compositions comprising organic sunscreens in more than the usual or the standard amounts in combination with silicone elastomers.

In accordance with a first aspect is disclosed a cosmetic composition comprising:.

In accordance with a second aspect is disclosed a packaged personal care product comprising the cosmetic composition of the first aspect of this invention.

In accordance with a first aspect is disclosed a composition of the first aspect for use in treatment for providing photoprotection to skin.

All amounts are by weight of the cosmetic composition, unless otherwise specified.

It should be noted that in specifying any ranges of values, any particular upper value can be associated with any particular lower value.

By a cosmetic composition is meant a composition for external application in the form of a leave-on or wash-off format meant for cleaning or care of the skin. Such a composition includes any product applied to a human body for improving appearance, cleansing or general aesthetics. The compositions in accordance with the invention are rinse off-products. Alternatively, and more preferably they are leave-on products. The composition of the present invention may be in the form of a liquid, lotion, cream, foam or gel, or toner, or applied with an implement or via a face mask, pad or patch. "Skin" as used herein is meant to include skin on the face and body (e.g., neck, chest, back, arms, underarms, hands, legs, buttocks and scalp).

The compositions in accordance with this invention comprise an organic sunscreen.

The organic sunscreen may be a UV-A sunscreen agent selected from a group consisting of dibenzoylmethane or derivatives thereof, a triazine derivative, or benzophenone or a derivative thereof, preferably a derivative of dibenzoylmethane, for example, butyl methoxydibenzoylmethane (sold under the trade name Parsol® <NUM>).

The organic sunscreen may comprise a UV-B sunscreen agent selected from a group consisting of a benzophenone, an anthranilate, a salicylate, a cinnamate, a camphore, benzylidene malonate, a triazone or a derivative thereof, preferably a cinnamate derivative, for example, ethylhexyl methoxycinnamate (sold under the trade name Parsol® MCX).

Typically, the composition of the present invention comprises from <NUM> to <NUM>% by weight of the organic sunscreen agent, more preferably from <NUM> to <NUM>%, most preferably from <NUM> to <NUM>%, based on the total weight of the composition.

Silicone elastomer gel, as used herein, means cross-linked silicone polymer gel that swells significantly in a non-silicone solvent forming a space filling material which behaves as a visco-elastic soft solid. Alkyl mole content as used herein, means the ratio of moles of alkyl substituted dimethicone units to the total moles of dimethicone units per mole of silicone elastomer unit, unless otherwise specified. The term "gel" as used herein means that the silicone elastomer in the cosmetic compositions of the invention is not particulate.

Phenyl mole content as used herein, means the ratio of moles of phenyl substituted dimethicone units to the total number of dimethicone units per mole of silicone elastomer gel unit, unless otherwise specified.

The silicone elastomer gel has the following formula:
<CHM>
wherein:.

Silicone elastomer gels suitable for use in the cosmetic compositions of the present invention are functional silicone elastomers that are modified by grafting functional groups onto the backbones of elastomers. It is preferred that the silicone elastomer gel is alkyl modified, phenyl modified or more preferably dual (alkyl and phenyl) modified silicone elastomer gels.

Alkyl modified silicone elastomer gels may be prepared from the reaction of a) a silicone-hydride containing polysiloxane; b) an alkene; and c) a vinyl-terminated dimethylpolysiloxane by using a hydrosilylation catalyst. In the reaction, the alkene reacts with the silicone-hydride containing polysiloxane to form an alkyl modified polysiloxane, which reacts with the vinyl-terminated dimethylpolysiloxane to form the alkyl modified silicone elastomer gel.

When the silicone elastomer gel is alkyl modified or dual modified as disclosed earlier, it is preferred that the alkyl mole content is <NUM> to <NUM>, more preferably from <NUM> to <NUM>.

Preferably the silicone elastomer gel has the following general formula:
<CHM>
wherein:.

Phenyl modified silicone elastomer gel may be prepared from the reaction of a silicone-hydride containing polysiloxane; and a vinyl-terminated dimethyl phenyl polysiloxane by using a hydrosilylation catalyst. Phenyl mole content as used herein, means the ratio of moles of phenyl substituted dimethicone units to the total moles of dimethicone units of the vinyl-terminated dimethyl phenyl polysiloxane. Preferably the phenyl content of the vinyl-terminated dimethyl phenyl polysiloxane is <NUM> to <NUM>%, more preferably <NUM> to <NUM>% and most preferably from <NUM> to <NUM>%. Preferably the phenyl mole content of the phenyl modified silicone elastomer gel is typically in the range from <NUM> to <NUM>, more preferably from <NUM> to <NUM>.

As an alternative to the structure disclosed as (II) above, a phenyl modified functional silicone elastomer gel has the following preferred general formula:
<CHM>
wherein:.

Dual (alkyl and phenyl) modified silicone elastomer gel may be prepared from the reaction of a silicone-hydride containing polysiloxane; an alkene; and a vinyl-terminated dimethyl phenyl polysiloxane by using a hydrosilylation catalyst.

The alkyl mole content of the dual (alkyl and phenyl) modified silicone elastomer gel is preferably in the range of <NUM> to <NUM>, more preferably from <NUM> to <NUM>.

The phenyl mole content of the dual (alkyl and phenyl) modified silicone elastomer gel is preferably in the range of <NUM> to <NUM>, preferably from <NUM> to <NUM>.

It is preferred that the dual (alkyl and phenyl) modified silicone elastomer gel has the general formula:
<CHM>
wherein:.

Further, it is particularly preferred that in the cosmetic compositions of the present invention, the silicone elastomer gel is of the Formula (IV) (i.e., the dual functional elastomer).

The compositions of the present invention comprise less than <NUM> wt% crosslinked elastomeric silicone polyether, more preferably less than <NUM> wt%, most preferably less than <NUM> wt%. The crosslinked elastomeric silicone polyethers and method of preparing such elastomers are disclosed in <CIT>.

The compositions of the present invention comprise a non-silicone solvent for the silicone elastomer gel.

Generally, silicone elastomer gels are made available and used in the form of a blend of the silicone elastomer gel and the non-silicone solvent which is a dispersion of the silicone elastomer gel in the non-silicone solvent. The blends of silicone elastomer gel and non-silicone solvent are cross-linked gels that can be prepared by hydrosilylation reaction. The reaction involves low levels of catalyst, usually platinum derivatives, and is generally run into an adequate solvent. Silicone-hydride (SiH) containing silicone polymers are reacted with di-vinyl materials to link independent silicone chains.

The non-silicone solvent is a hydrocarbon, more preferably an alkane, most preferably an alkane having a carbon chain length of <NUM> to <NUM> carbon atoms. Examples of commercially available non-silicone solvents which are hydrocarbons include Cetiol® Ultimate from BASF which is the mixture of Undecane and Tridecane, EMOSMART® L15 (C13-C15 alkane) and EMOGREEN® L15 (C15-C19 alkane) from Seppic, LexFeel® WOW-DT from Inolex which is Heptyl Undecylenate and C13-C16 Isoparaffin.

Under a shearing force, the elastomer swells in the presence of the non-silicone solvent. Preferably the silicone elastomer gel and the non-silicone solvent for said elastomer are present in the form of a blend of which, the silicone elastomer gel forms <NUM> to <NUM> parts by weight of the blend, more preferably from <NUM> to <NUM> parts by weight, most preferably from <NUM> to <NUM> parts by weight, the balancing being the non-silicone solvent. The reference to parts by weight here is with regard to the blend and not the cosmetic composition which comprises such a blend. In the finished product, for example, in a skincare lotion, it may not be possible to identify that the elastomer and the non-silicone solvent for the elastomer were introduced/added together as a blend but usually when the silicone elastomer is a gel and the non-silicone solvent is also present in the concerned composition, that itself may serve as an indication that when the composition was prepared, the elastomer and the non-silicone solvent were co-dosed and the elastomer is in the form of a gel, as opposed to particulate elastomers which might permit the introduction of the elastomer as such in the form of particles. When the elastomer and the non-silicone solvent for the elastomer are introduced as a blend, the formulation scientist needs to know the solids content of the blend (e.g., <NUM>% solids, <NUM>% solids) so that a calculated amount of the blend can be added to the composition to ensure that the composition contains a desired amount of the elastomer.

The compositions of the present invention comprise <NUM> to <NUM> wt%, more preferably <NUM> to <NUM> wt% and most preferably <NUM> to <NUM> wt% blend of the silicone elastomer gel and the non-silicone solvent for the elastomer.

The personal care composition of the invention may be in any form including toners, lotions, creams, mousses, serum or gel that is suitable for topical application to the skin. The cosmetic composition can be either a leave-on or a rinse-off product, preferably a leave-on product, especially a skin care product including skin lotions and skin creams.

The cosmetic composition of the present invention may further comprise <NUM> to <NUM> wt% of a hydrocarbon emollient. Suitable emollients include wax, cyclic hydrocarbons, straight chain aliphatic hydrocarbons (saturated or unsaturated), and branched chain aliphatic hydrocarbons (saturated or unsaturated).

The cosmetic compositions of the invention preferably comprise a cosmetically acceptable carrier. The carrier may be a liquid or solid material. Typically, carrier forms <NUM> to <NUM>%, more preferably <NUM> to <NUM>%, most preferably <NUM> to <NUM>% of the composition. Suitable carrier classes include water, silicones other than the silicone which are covered by the silicone elastomer gel of the Formula (I); polyhydric alcohols, hydrocarbons, and thickening powders.

The cosmetic composition of the invention comprises less than <NUM> wt% volatile silicone solvent.

In one aspect the cosmetic compositions of the invention are anhydrous. Anhydrous, as used herein, refers to a composition comprises less than <NUM>% by weight of water, preferably less than <NUM>%.

Alternatively, and more preferably the compositions of the invention comprise <NUM> to <NUM> wt%, more preferably <NUM> to <NUM> wt% and most preferably <NUM> to <NUM> wt% water.

Further preferably the compositions of the invention comprise a skin lightening agent. The skin lightening agent is preferably chosen from one or more of a vitamin B3 compound or its derivative e.g. niacin, nicotinic acid or niacinamide or other well-known skin lightening agents e.g. adapalene, aloe extract, ammonium lactate, anethole derivatives, apple extract, arbutin, azelaic acid, kojic acid, bamboo extract, bearberry extract, bletilla tuber, bupleurum falcatum extract, burnet extract, butyl hydroxy anisole, butyl hydroxy toluene, citrate esters, Chuanxiong, Dang-Gui, deoxyarbutin, <NUM>,<NUM>-diphenyl propane derivatives, <NUM>,<NUM>-dihydroxybenzoic acid and its derivatives, <NUM>-(<NUM>-acetoxyphenyl)-<NUM>,<NUM>-dithane, <NUM>-(<NUM>- hydroxyphenyl)-<NUM>,<NUM>-dithane, ellagic acid, escinol, estragole derivatives, Fadeout® (Pentapharm), Fangfeng, fennel extract, ganoderma extract, gaoben, Gatuline Whitening (Gattlefosse), genistic acid and its derivatives, glabridin and its derivatives, gluco pyranosyl-<NUM>-ascorbate, gluconic acid, glycolic acid, green tea extract, <NUM>-hydroxy-<NUM>-methyl- <NUM>[<NUM>]-furanone, hydroquinone, <NUM>-hydroxyanisole and its derivatives, <NUM>-hydroxy benzoic acid derivatives, hydroxycaprylic acid, inositol ascorbate, lemon extract, linoleic acid, magnesium ascorbyl phosphate, Melawhite® (Pentapharm), morus alba extract, mulberry root extract, <NUM>-octanoyl salicylic acid, parsley extract, phellinus linteus extract, pyrogallol derivatives, <NUM>,<NUM>-resorcinol derivatives, <NUM>,<NUM>-resorcinol derivatives, rose fruit extract, salicylic acid, Song-Yi extract, <NUM>,<NUM>,<NUM>-trihydroxybenzyl derivatives, tranexamic acid, vitamins like vitamin B6, vitamin B12, vitamin C, vitamin A, dicarboxylic acids, resorcinol derivatives, extracts from plants viz. rubia and symplocos, hydroxycarboxylic acids like lactic acid and their salts e.g. sodium lactate, and mixtures thereof. Vitamin B3 compound or its derivative e.g. niacin, nicotinic acid or niacinamide are the more preferred skin lightening agent as per the invention, most preferred being niacinamide. Niacinamide, when used, is preferably <NUM> to <NUM> wt%, more preferably <NUM> to <NUM> wt%.

Other materials which can be included in the cosmetically acceptable carrier include humectants, thickeners and powders. Examples of each of these types of material, which can be used singly or as mixtures, are as follows:
Humectants include those of the polyhydric alcohol-type. Typical polyhydric alcohols include polyalkylene glycols and more preferably alkylene polyols and their derivatives, including propylene glycol, dipropylene glycol, polypropylene glycol, polyethylene glycol and derivatives thereof, sorbitol, hydroxypropyl sorbitol, hexylene glycol, <NUM>,<NUM>-butylene glycol, isoprene glycol, <NUM>,<NUM>,<NUM>-hexanetriol, glycerol, ethoxylated glycerol, propoxylated glycerol and mixtures thereof. The amount of humectant may range, for example, anywhere from <NUM> to <NUM>%, more preferably between <NUM> and <NUM>% by weight of the composition. Most preferred is glycerol (also known as glycerin). Amounts of glycerin may range, for example, from <NUM>% to <NUM>%, more preferably from <NUM> to <NUM>%, optimally from <NUM> to <NUM>% by weight of the composition.

A variety of thickening agents may be included in the compositions. Illustrative but not limiting are stearic acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer (Aristoflex® AVC), Hydroxyethyl Acrylate/Sodium Acryloyldimethyltaurate Copolymer, Aluminum Starch Octenyl Succinate, Polyacrylates (such as Carbomers including Carbopol® <NUM>, Carbopol® <NUM>, Pemulen TR-<NUM>® and the Ultrez® thickeners), Polysaccharides (including xanthan gum, guar gum, pectin, carageenan and sclerotium gums), celluloses (including carboxymethyl cellulose, ethyl cellulose, hydroxyethyl cellulose and methyl hydroxymethyl cellulose), minerals (including talc, silica, alumina, mica and clays, the latter being represented by bentonites, hectorites and attapulgites), magnesium aluminum silicate and mixtures thereof. Amounts of the thickeners may range, for example, from <NUM> to <NUM> wt%, more preferably from <NUM> to <NUM> wt% by weight of the composition.

Powders include chalk, talc, Fuller's earth, kaolin, starch, gums, colloidal silica sodium polyacrylate, tetraalkyl and/or trialkyl aryl ammonium smectites, chemically modified magnesium aluminium silicate, organically modified montmorillonite clay, hydrated aluminium silicate, fumed silica, carboxyvinyl polymer, sodium carboxymethyl cellulose and ethylene glycol monostearate.

The cosmetic compositions of the invention may further comprise other ingredients which are common in the art to enhance physical properties and performances. Suitable ingredients include, but are not limited to opacifiers, binders, colorants and pigments, pH adjusting agents, preservatives, optics, perfumes, viscosity modifiers, biological additives, buffering agents, conditioners, natural extracts, essential oils and skin benefit agents including anti-inflammatory agents, cooling agents, antiperspirant agents, anti-aging agents, anti-acne agents, anti-microbial agents and antioxidants.

A wide variety of packaging can be employed to store and deliver the cosmetic compositions. Packaging is often dependent upon the type of personal care end-use. For instance, leave-on skin lotions and creams, shampoos, hair conditioners and shower gels generally employ plastic containers with an opening at a dispensing end covered by a closure. Typical closures are screw-caps, non-aerosol pumps and flip-top hinged lids. Packaging for antiperspirants, deodorants and depilatories may involve a container with a roll-on ball on a dispensing end. Alternatively, of the compositions of the invention may be delivered as a stick formulation in a container with propel-repel mechanism where the stick moves on a platform towards a dispensing orifice. Metallic cans pressurized by a propellant and having a spray nozzle serve as packaging for antiperspirants, shave creams and other sprayable personal care products.

In accordance with another aspect is disclosed a method of providing photoprotection to skin comprising a step of topically applying a cosmetic composition of the first aspect to the skin. Preferably the method is non-therapeutic. By non-therapeutic is meant that the method is for cosmetic purpose. Alternatively, the method is therapeutic in nature.

In accordance with another aspect is disclosed use of a cosmetic composition of the first aspect for photoprotection of the skin. Preferably the use is for non-therapeutic purpose. By non-therapeutic is meant that the use is for cosmetic purpose. Alternatively, the use is therapeutic in nature.

The following examples are provided to facilitate an understanding of the present invention. The examples are not provided to limit the scope of the claims.

Silicone-hydride containing polysiloxane (Andisil XL-<NUM>), vinyl-terminated dimethylpolysiloxane (Andisil VS-<NUM>), vinyl-terminated dimethyl diphenyl polysiloxane (Andisil SF-<NUM>) were purchased from AB Specialty Silicones.

Decamethylcyclopentasiloxane (DC245) was purchased from Dow Corning Corporation. Cetiol ® Ultimate (Mixture of C11 and C13 alkane) was purchased from BASF Corporation. All the chemicals were used as received without further purification.

Solids content, as used herein, refers to the weight percentage of silicone elastomers in the blend of silicone elastomer and the non-silicone solvent.

<NUM> Andisil XL-<NUM>, <NUM> dodecene and <NUM> Cetiol® Ultimate were mixed and stirred in a vial, followed by the addition of <NUM> platinum complex catalyst. The mixture was stirred at <NUM> for <NUM> minutes. Then the reaction mixture was transferred to a flask. <NUM> Cetiol® Ultimate, <NUM> Andisil SF-<NUM> and <NUM> platinum complex catalyst were added to the mixture and the mixture was kept at <NUM> with the reflux of water and stirred at <NUM> rpm for <NUM> hours. This led to the formation of a silicone elastomer gel in the solvent which could be diluted to different solids contents at <NUM> after the reaction was complete.

<NUM> Andisil XL-<NUM>, <NUM> dodecene and <NUM> DC245 were mixed and stirred in a vial, followed by the addition of <NUM>µL platinum complex catalyst. The mixture was stirred at <NUM> for <NUM> minutes. Then the reaction mixture was transferred to a flask. <NUM> DC245, <NUM> Andisil SF-<NUM> and <NUM>µL platinum complex catalyst were added to the mixture and the mixture was kept at <NUM> with the reflux of water and stirred at <NUM> rpm for <NUM> hours. This led to the formation of a silicone elastomer gel as per structure (I) in the solvent which could be diluted to different solids contents at <NUM> after the reaction was complete.

Cosmetic compositions in the form of creams were prepared by using the blends (as described above) and certain amount of sunscreens as further described hereinafter.

Details of the compositions comprising silicone elastomer and sunscreen are shown in Table <NUM>. All ingredients are expressed by weight percent by the total composition, and as level of active ingredient, except the silicone elastomer blend.

In order to determine whether the compositions were stable or not (upon storage under varying conditions), certain tests were performed. Details thereof are described hereinafter.

DV-II PRO Digital Viscometer (from Brookfield Ltd) was used to measure the viscosities of the roll on samples at a consistent shear rate of <NUM> rpm. This viscometer was connected with PC where an automate program can control the measurement. The values measured after <NUM> at a temperature of <NUM> was used. Values are quoted in centipoises (cP=mPa·S) unless otherwise specified.

Stability, as used herein, refers to the concerned composition maintaining its appearance, odor and main structure without phase separation. Samples of the compositions were poured into plastic bottles and filled up to <NUM>/<NUM> of the bottles. Then the samples were stored at <NUM> in a fridge and <NUM> in an oven. For stability test, samples were checked daily. The appearance of samples was observed and recorded. The observation was taken when the samples were still cold/warm and then the samples were left in the fridge/oven for <NUM> hours before another observation was taken.

The observations pertaining to the compositions of Table <NUM> are tabulated in Table <NUM>.

Claim 1:
A cosmetic composition comprising:
(i) <NUM> to <NUM> wt% of an organic sunscreen; and
(ii) <NUM> to <NUM> wt% of a blend comprising a silicone elastomer gel of the Formula (I) and a non-silicone solvent selected from a hydrocarbon, an oil, a modified oil, an ester, an ether, an alcohol or a mixture thereof;
<CHM>
wherein:
each R<NUM> is independently, C<NUM>-<NUM> alkyl chain, preferably C<NUM>-<NUM> alkyl chain;
each R<NUM> is independently, phenyl or CH<NUM>;
each R<NUM> is phenyl; and
each x is independently an integer from <NUM> to <NUM>, preferably from <NUM> to <NUM>; each y is independently an integer from <NUM> to <NUM>, preferably from <NUM> to <NUM>; each z is independently an integer from <NUM> to <NUM>, preferably from <NUM> to <NUM>; each m is independently an integer from <NUM> to <NUM>, preferably from <NUM> to <NUM>; and each n is independently an integer from <NUM> to <NUM>, preferably from <NUM> to <NUM>,
and wherein: a) the composition comprises less than <NUM> wt% volatile silicone solvent; and b) said non-silicone solvent is a hydrocarbon.