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0 | Kim, J.; Scott, S.V.; Oda, M.N.; Klionsky, D.J. | Transport of a large oligomeric protein by the cytoplasm to vacuole protein targeting pathway | J. Cell Biol. | 137 | 609-618 | 1,997 | 9,151,668 | /home/data/brenda/literatur/neuePDFsVonTool/9151668.pdf | 2,139,888 | true | 10.1083/jcb.137.3.609 | 2025-01-15T19:04:03.596837+00:00 | [2477] | {} | [] | {'984': 'Saccharomyces cerevisiae'} | {'HasEnzyme': [{'subject': 984, 'object': 2477}]} | Aminopeptidase I (API) is transported into the yeast vacuole by the cytoplasm to vacuole targeting (Cvt) pathway. Genetic evidence suggests that autophagy, a major degradative pathway in eukaryotes, and the Cvt pathway share largely the same cellular machinery. To understand the mechanism of the Cvt import process, we ... | 2025-01-15T19:04:03.596837+00:00 | [] | <jats:body xmlns:jats="https://jats.nlm.nih.gov/ns/archiving/1.3/">
<jats:p>The faithful transport of resident organellar proteins is a hallmark in maintaining the functional characteristics and integrity of eukaryotic cells. All nuclearencoded proteins delivered to their respective organelles must cross at least o... |
1 | Scott, S.V.; Baba, M.; Ohsumi, Y.; Klionsky, D.J. | Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism | J. Cell Biol. | 138 | 37-44 | 1,997 | 9,214,379 | /home/data/brenda/literatur/neuePDFsVonTool/9214379.pdf | 2,139,945 | true | 10.1083/jcb.138.1.37 | 2025-01-15T19:04:04.644486+00:00 | [2477] | {} | [] | {'984': 'Saccharomyces cerevisiae'} | {'HasEnzyme': [{'subject': 984, 'object': 2477}]} | The yeast vacuolar protein aminopeptidase I (API) is synthesized as a cytosolic precursor that is transported to the vacuole by a nonclassical targeting mechanism. Recent genetic studies indicate that the biosynthetic pathway that transports API uses many of the same molecular components as the degradative autophagy pa... | 2025-01-15T19:04:04.644486+00:00 | [] | <jats:body xmlns:jats="https://jats.nlm.nih.gov/ns/archiving/1.3/">
<jats:p>The yeast vacuole plays a key role in cellular protein metabolism. During periods of nitrogen starvation, amino acid supplies are maintained by protein degradation reactions that take place in this organelle (<jats:xref ref-type="bibr" rid=... |
2 | Shi, G.P.; Bryant, R.A.R.; Riese, R.; Verhelst, S.; Driessen, C.; Li, Z.; Brömme, D.; Ploegh, H.L.; Capman, H.A. | Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages | J. Exp. Med. | 191 | 1177-1185 | 2,000 | 10,748,235 | /home/data/brenda/literatur/neuePDFsVonTool/10748235.pdf | 2,193,169 | true | 10.1084/jem.191.7.1177 | 2025-01-15T19:34:17.284676+00:00 | [19204] | {} | [] | {'3474': 'Mus musculus'} | {'HasEnzyme': [{'subject': 3474, 'object': 19204}]} | The major histocompatibility complex (MHC) class II-associated invariant chain (Ii) regulates intracellular trafficking and peptide loading of MHC class II molecules. Such loading occurs after endosomal degradation of the invariant chain to a approximately 3-kD peptide termed CLIP (class II-associated invariant chain p... | 2025-01-15T19:34:17.284676+00:00 | [] | <jats:body xmlns:jats="https://jats.nlm.nih.gov/ns/archiving/1.3/">
<jats:sec>
<jats:title>Introduction</jats:title>
<jats:p>The MHC class II–associated invariant chain (Ii) is a type II transmembrane protein that binds to the peptide binding groove of newly synthesized MHC class II α/β heterodimers, th... |
3 | Weinreich, F.; Riordan, J.R.; Nagel, G. | "Dual effects of ADP and adenylylimidodiphosphate on CFTR channel kinetics show binding to two diffe(...TRUNCATED) | J. Gen. Physiol. | 114 | 55-70 | 1,999 | 10,398,692 | /home/data/brenda/literatur/neuePDFsVonTool/10398692.pdf | 2,229,643 | true | 10.1085/jgp.114.1.55 | 2025-01-15T19:45:00.982708+00:00 | [26828] | {} | [] | {'2681': 'Homo sapiens'} | {'HasEnzyme': [{'subject': 2681, 'object': 26828}]} | "The CFTR chloride channel is regulated by phosphorylation by protein kinases, especially PKA, and b(...TRUNCATED) | 2025-01-15T19:45:00.982708+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:sec>\n <jats:(...TRUNCATED) |
4 | Ahmad, F.J.; Yu, W.; McNally, F.J.; Baas, P.W. | An essential role for katanin in severing microtubules in the neuron | J. Cell Biol. | 145 | 305-315 | 1,999 | 10,209,026 | /home/data/brenda/literatur/neuePDFsVonTool/10209026.pdf | 2,133,110 | true | 10.1083/jcb.145.2.305 | 2025-01-15T19:45:25.739545+00:00 | [26836] | {} | [] | {'6140': 'Strongylocentrotus purpuratus', '5301': 'Rattus norvegicus', '2681': 'Homo sapiens'} | "{'HasEnzyme': [{'subject': 2681, 'object': 26836}, {'subject': 5301, 'object': 26836}, {'subject': (...TRUNCATED) | "Several lines of evidence suggest that microtubules are nucleated at the neuronal centrosome, and t(...TRUNCATED) | 2025-01-15T19:45:25.739545+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:p>A<jats:sc>xons</(...TRUNCATED) |
5 | Pollock, N.; de Hostos, E.L.; Turck, C.W.; Vale, R.D. | "Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A f(...TRUNCATED) | J. Cell Biol. | 147 | 493-506 | 1,999 | 10,545,495 | /home/data/brenda/literatur/neuePDFsVonTool/10545495.pdf | 2,151,178 | true | 10.1083/jcb.147.3.493 | 2025-01-15T19:45:31.074383+00:00 | [26837] | {} | [] | "{'3474': 'Mus musculus', '1045': 'Caenorhabditis elegans', '2711': 'Thermomyces lanuginosus', '1939(...TRUNCATED) | "{'HasEnzyme': [{'subject': 1045, 'object': 26837}, {'subject': 1939, 'object': 26837}, {'subject': (...TRUNCATED) | "Motor-powered movement along microtubule tracks is important for membrane organization and traffick(...TRUNCATED) | 2025-01-15T19:45:31.074383+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:p>M<jats:sc>ovemen(...TRUNCATED) |
6 | Tomishige, M.; Vale, R.D. | "Controlling kinesin by reversible disulfide cross-linking. Identifying the motility-producing confo(...TRUNCATED) | J. Cell Biol. | 151 | 1081-1092 | 2,000 | 11,086,009 | /home/data/brenda/literatur/neuePDFsVonTool/11086009.pdf | 2,174,365 | true | 10.1083/jcb.151.5.1081 | 2025-01-15T19:45:31.843846+00:00 | [26837] | {} | [] | {'2681': 'Homo sapiens'} | {'HasEnzyme': [{'subject': 2681, 'object': 26837}]} | "Conventional kinesin, a dimeric molecular motor, uses ATP-dependent conformational changes to move (...TRUNCATED) | 2025-01-15T19:45:31.843846+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:sec>\n <jats:(...TRUNCATED) |
7 | Titorenko, V.I.; Chan, H.; Rachubinski, R.A. | "Fusion of small peroxisomal vesicles in vitro reconstructs an early step in the in vivo multistep p(...TRUNCATED) | J. Cell Biol. | 148 | 29-44 | 2,000 | 10,629,216 | /home/data/brenda/literatur/neuePDFsVonTool/10629216.pdf | 2,156,211 | true | 10.1083/jcb.148.1.29 | 2025-01-15T19:45:40.914889+00:00 | [26840] | {} | [] | "{'984': 'Saccharomyces cerevisiae', '2681': 'Homo sapiens', '1122': 'Yarrowia lipolytica', '4827': (...TRUNCATED) | "{'HasEnzyme': [{'subject': 984, 'object': 26840}, {'subject': 1122, 'object': 26840}, {'subject': 2(...TRUNCATED) | "We have identified and purified six subforms of peroxisomes, designated P1 to P6, from the yeast, Y(...TRUNCATED) | 2025-01-15T19:45:40.914889+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:sec>\n <jats:(...TRUNCATED) |
8 | "Kubata, B.K.; Duszenko, M.; Kabututu, Z.; Rawer, M.; Szallies, A.; Fujimori, K.; Inui, T.; Nozaki, (...TRUNCATED) | Identification of a novel prostaglandin F2.alpha. synthase in Trypanosoma brucei | J. Exp. Med. | 192 | 1327-1337 | 2,000 | 11,067,881 | null | 2,193,354 | true | 10.1084/jem.192.9.1327 | 2025-01-15T20:03:42.066966+00:00 | [44016] | {} | [] | {'6519': 'Trypanosoma brucei'} | {'HasEnzyme': [{'subject': 6519, 'object': 44016}]} | "Members of the genus Trypanosoma cause African trypanosomiasis in humans and animals in Africa. Inf(...TRUNCATED) | 2025-01-15T20:03:42.066966+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:sec>\n <jats:(...TRUNCATED) |
9 | Frumento, G.; Rotondo, R.; Tonetti, M.; Damonte, G.; Benatti, U.; Ferrara, G.B. | "Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell prolifer(...TRUNCATED) | J. Exp. Med. | 196 | 459-468 | 2,002 | 12,186,838 | /home/data/brenda/literatur/neuePDFsVonTool/12186838.pdf | 2,196,046 | true | 10.1084/jem.20020121 | 2025-01-15T20:19:32.413643+00:00 | [64042] | {} | [] | {'1749': 'Oryctolagus cuniculus'} | {'HasEnzyme': [{'subject': 1749, 'object': 64042}]} | "Macrophages exposed to macrophage colony-stimulating factor acquire the capacity to suppress T cell(...TRUNCATED) | 2025-01-15T20:19:32.413643+00:00 | [] | "<jats:body xmlns:jats=\"https://jats.nlm.nih.gov/ns/archiving/1.3/\">\n <jats:sec>\n <jats:(...TRUNCATED) |
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