text stringlengths 51 189 | input stringlengths 51 189 | output stringclasses 1
value | answer_choices sequencelengths 0 0 | correct_output_index float64 |
|---|---|---|---|---|
The sequence of amino acids GLLPLLSLLGKLL shows hemolytic properties. | The sequence of amino acids GLLPLLSLLGKLL shows hemolytic properties. | [] | null | |
The sequence of amino acids FAKKLAKKLKKLAKKLAKKWKL demonstrates hemolytic properties. | The sequence of amino acids FAKKLAKKLKKLAKKLAKKWKL demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids RKGSRMGKKCECP shows hemolytic properties. | The sequence of amino acids RKGSRMGKKCECP shows hemolytic properties. | [] | null | |
The sequence of amino acids AGKETIRQFLKKKIQEWKKRATIAW exhibits hemolytic properties. | The sequence of amino acids AGKETIRQFLKKKIQEWKKRATIAW exhibits hemolytic properties. | [] | null | |
The sequence of amino acids GGHKWKLFKKIGAVLKVL shows hemolytic properties. | The sequence of amino acids GGHKWKLFKKIGAVLKVL shows hemolytic properties. | [] | null | |
The sequence of AAs ERR shows hemolytic properties. | The sequence of AAs ERR shows hemolytic properties. | [] | null | |
The sequence of amino acids GFLSILKKVLKKVMAHMK shows hemolytic properties. | The sequence of amino acids GFLSILKKVLKKVMAHMK shows hemolytic properties. | [] | null | |
The sequence of AAs RRLCRIVWVIRVCRR demonstrates hemolytic properties. | The sequence of AAs RRLCRIVWVIRVCRR demonstrates hemolytic properties. | [] | null | |
The sequence of AAs IFWLFRGKADVAL demonstrates hemolytic properties. | The sequence of AAs IFWLFRGKADVAL demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids KIAGKIAKIAGKIAKIAGKIAKIA exhibits hemolytic properties. | The sequence of amino acids KIAGKIAKIAGKIAKIAGKIAKIA exhibits hemolytic properties. | [] | null | |
The sequence of AAs KWKKLLKKLLKLL demonstrates hemolytic properties. | The sequence of AAs KWKKLLKKLLKLL demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids FLPMLAGLAASMVPKLVCLITKKC shows hemolytic properties. | The sequence of amino acids FLPMLAGLAASMVPKLVCLITKKC shows hemolytic properties. | [] | null | |
The sequence of AAs GLFDVIKKVASVIGPLG shows hemolytic properties. | The sequence of AAs GLFDVIKKVASVIGPLG shows hemolytic properties. | [] | null | |
The sequence of amino acids RWCGYAYVRVRGVLVRYRRCW exhibits hemolytic properties. | The sequence of amino acids RWCGYAYVRVRGVLVRYRRCW exhibits hemolytic properties. | [] | null | |
The sequence of amino acids ILPWKWPWWAWRR shows hemolytic properties. | The sequence of amino acids ILPWKWPWWAWRR shows hemolytic properties. | [] | null | |
The sequence of amino acids GILDTIKSIASKVWNSKTVQDLKRKGINWVANKLGVSPQAA shows hemolytic properties. | The sequence of amino acids GILDTIKSIASKVWNSKTVQDLKRKGINWVANKLGVSPQAA shows hemolytic properties. | [] | null | |
The sequence of AAs KRRLIARILRLAARALVKKR exhibits hemolytic properties. | The sequence of AAs KRRLIARILRLAARALVKKR exhibits hemolytic properties. | [] | null | |
The sequence of AAs KLLLKLLLKLLK exhibits hemolytic properties. | The sequence of AAs KLLLKLLLKLLK exhibits hemolytic properties. | [] | null | |
The sequence of amino acids FFGKVLKLIRKIF shows hemolytic properties. | The sequence of amino acids FFGKVLKLIRKIF shows hemolytic properties. | [] | null | |
The sequence of amino acids DAHKLAKLAKKLAKLAK shows hemolytic properties. | The sequence of amino acids DAHKLAKLAKKLAKLAK shows hemolytic properties. | [] | null | |
The sequence of amino acids FWGTLAKWALK exhibits hemolytic properties. | The sequence of amino acids FWGTLAKWALK exhibits hemolytic properties. | [] | null | |
The sequence of AAs CLNLKALLAVAKKILC exhibits hemolytic properties. | The sequence of AAs CLNLKALLAVAKKILC exhibits hemolytic properties. | [] | null | |
The sequence of amino acids GLPVCGETCVGGTCNTPGCSCSWPVCTRN exhibits hemolytic properties. | The sequence of amino acids GLPVCGETCVGGTCNTPGCSCSWPVCTRN exhibits hemolytic properties. | [] | null | |
The sequence of AAs GIKKFLHIIWKFIKAFVGEIMNS demonstrates hemolytic properties. | The sequence of AAs GIKKFLHIIWKFIKAFVGEIMNS demonstrates hemolytic properties. | [] | null | |
The sequence of AAs AGTNRIAKELRRYIRKVGRIKRKAW shows hemolytic properties. | The sequence of AAs AGTNRIAKELRRYIRKVGRIKRKAW shows hemolytic properties. | [] | null | |
The sequence of AAs GWGDTFGKVLKNFAKVAGVKAAK exhibits hemolytic properties. | The sequence of AAs GWGDTFGKVLKNFAKVAGVKAAK exhibits hemolytic properties. | [] | null | |
The sequence of AAs IIGPVLGLVGSALGGLLKKI shows hemolytic properties. | The sequence of AAs IIGPVLGLVGSALGGLLKKI shows hemolytic properties. | [] | null | |
The sequence of AAs RWCVYAYVRVRGVLSRYRRCW exhibits hemolytic properties. | The sequence of AAs RWCVYAYVRVRGVLSRYRRCW exhibits hemolytic properties. | [] | null | |
The sequence of AAs FLPGLIKAAVGIGSTIFCKISRKC demonstrates hemolytic properties. | The sequence of AAs FLPGLIKAAVGIGSTIFCKISRKC demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids FLKGIVGMLGKLW demonstrates hemolytic properties. | The sequence of amino acids FLKGIVGMLGKLW demonstrates hemolytic properties. | [] | null | |
The sequence of AAs RVKRFKKFFRKIKKGFRKIFKKTKIFIG demonstrates hemolytic properties. | The sequence of AAs RVKRFKKFFRKIKKGFRKIFKKTKIFIG demonstrates hemolytic properties. | [] | null | |
The sequence of AAs MGIIAGIIKVIKSLIEQFTGK exhibits hemolytic properties. | The sequence of AAs MGIIAGIIKVIKSLIEQFTGK exhibits hemolytic properties. | [] | null | |
The sequence of AAs WKWPWWPWRR shows hemolytic properties. | The sequence of AAs WKWPWWPWRR shows hemolytic properties. | [] | null | |
The sequence of AAs LRFLKKILKHLF demonstrates hemolytic properties. | The sequence of AAs LRFLKKILKHLF demonstrates hemolytic properties. | [] | null | |
The sequence of AAs FLGALLKIGAKVLPSVLCGIFKKC shows hemolytic properties. | The sequence of AAs FLGALLKIGAKVLPSVLCGIFKKC shows hemolytic properties. | [] | null | |
The sequence of amino acids KLALKLALKAWKAALKLA demonstrates hemolytic properties. | The sequence of amino acids KLALKLALKAWKAALKLA demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids FLFSLIPSAIAGLVSAIRN shows hemolytic properties. | The sequence of amino acids FLFSLIPSAIAGLVSAIRN shows hemolytic properties. | [] | null | |
The sequence of AAs VWPLVIRTVIAGYNLYRAIKKK demonstrates hemolytic properties. | The sequence of AAs VWPLVIRTVIAGYNLYRAIKKK demonstrates hemolytic properties. | [] | null | |
The sequence of AAs FAKLLAKALKKLL exhibits hemolytic properties. | The sequence of AAs FAKLLAKALKKLL exhibits hemolytic properties. | [] | null | |
The sequence of AAs AIPWIWIWRLLRKG demonstrates hemolytic properties. | The sequence of AAs AIPWIWIWRLLRKG demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids VIHKLAKLAKKLAKLAK demonstrates hemolytic properties. | The sequence of amino acids VIHKLAKLAKKLAKLAK demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids LKKLLKLLKKLAKLAG demonstrates hemolytic properties. | The sequence of amino acids LKKLLKLLKKLAKLAG demonstrates hemolytic properties. | [] | null | |
The sequence of AAs ILGKLLSTAAGLLKNL demonstrates hemolytic properties. | The sequence of AAs ILGKLLSTAAGLLKNL demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids GIGKFLHKVKSFGKSWIGEIMNS demonstrates hemolytic properties. | The sequence of amino acids GIGKFLHKVKSFGKSWIGEIMNS demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids FFHHIFRGIVHVGKTIHRLVTG shows hemolytic properties. | The sequence of amino acids FFHHIFRGIVHVGKTIHRLVTG shows hemolytic properties. | [] | null | |
The sequence of AAs FLPIVAGLAANFLPKIVCKITKKC demonstrates hemolytic properties. | The sequence of AAs FLPIVAGLAANFLPKIVCKITKKC demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids RIGSILGALAKGLPTLISWIKNR exhibits hemolytic properties. | The sequence of amino acids RIGSILGALAKGLPTLISWIKNR exhibits hemolytic properties. | [] | null | |
The sequence of AAs GLWDVIKKVASVIGGL demonstrates hemolytic properties. | The sequence of AAs GLWDVIKKVASVIGGL demonstrates hemolytic properties. | [] | null | |
The sequence of AAs FLPLLLAGLPKLLCLFFKKC demonstrates hemolytic properties. | The sequence of AAs FLPLLLAGLPKLLCLFFKKC demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids MNGFILGKFFDVAKKILDTIFQK exhibits hemolytic properties. | The sequence of amino acids MNGFILGKFFDVAKKILDTIFQK exhibits hemolytic properties. | [] | null | |
The sequence of amino acids RKWWK shows hemolytic properties. | The sequence of amino acids RKWWK shows hemolytic properties. | [] | null | |
The sequence of AAs CKKLLKLCKKLLKLAG shows hemolytic properties. | The sequence of AAs CKKLLKLCKKLLKLAG shows hemolytic properties. | [] | null | |
The sequence of amino acids GLLSLLSALGKLL exhibits hemolytic properties. | The sequence of amino acids GLLSLLSALGKLL exhibits hemolytic properties. | [] | null | |
The sequence of AAs RRWQWR demonstrates hemolytic properties. | The sequence of AAs RRWQWR demonstrates hemolytic properties. | [] | null | |
The sequence of AAs KWCFRVCYRGICYRRCR demonstrates hemolytic properties. | The sequence of AAs KWCFRVCYRGICYRRCR demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids IWRIFRRIFRIF demonstrates hemolytic properties. | The sequence of amino acids IWRIFRRIFRIF demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids RWCVYAYVRVRGVLVRYRRCG demonstrates hemolytic properties. | The sequence of amino acids RWCVYAYVRVRGVLVRYRRCG demonstrates hemolytic properties. | [] | null | |
The sequence of AAs FFHHIFRGIVHVGKTAHRLVTG exhibits hemolytic properties. | The sequence of AAs FFHHIFRGIVHVGKTAHRLVTG exhibits hemolytic properties. | [] | null | |
The sequence of amino acids KWCSRVCYRGICSRRCRG demonstrates hemolytic properties. | The sequence of amino acids KWCSRVCYRGICSRRCRG demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids ILPWKWPWWPWRA demonstrates hemolytic properties. | The sequence of amino acids ILPWKWPWWPWRA demonstrates hemolytic properties. | [] | null | |
The sequence of AAs LMCTHPLDCSN shows hemolytic properties. | The sequence of AAs LMCTHPLDCSN shows hemolytic properties. | [] | null | |
The sequence of amino acids FFRHIKSFWKGAKAIFRGARQG shows hemolytic properties. | The sequence of amino acids FFRHIKSFWKGAKAIFRGARQG shows hemolytic properties. | [] | null | |
The sequence of AAs KKFLHSAKKWLKAFVKLFKNW exhibits hemolytic properties. | The sequence of AAs KKFLHSAKKWLKAFVKLFKNW exhibits hemolytic properties. | [] | null | |
The sequence of AAs FLHHIVGLIHHGKLDMYRSNN shows hemolytic properties. | The sequence of AAs FLHHIVGLIHHGKLDMYRSNN shows hemolytic properties. | [] | null | |
The sequence of amino acids AFLYRLTRQIRPWWRWLYKW demonstrates hemolytic properties. | The sequence of amino acids AFLYRLTRQIRPWWRWLYKW demonstrates hemolytic properties. | [] | null | |
The sequence of AAs LKKLLKLCKKLCKLAG shows hemolytic properties. | The sequence of AAs LKKLLKLCKKLCKLAG shows hemolytic properties. | [] | null | |
The sequence of AAs ILGKIWEGIKSLF demonstrates hemolytic properties. | The sequence of AAs ILGKIWEGIKSLF demonstrates hemolytic properties. | [] | null | |
The sequence of AAs KIAKGALKALKIAKVALKAL shows hemolytic properties. | The sequence of AAs KIAKGALKALKIAKVALKAL shows hemolytic properties. | [] | null | |
The sequence of amino acids IISTIGKLVKWIIDTV demonstrates hemolytic properties. | The sequence of amino acids IISTIGKLVKWIIDTV demonstrates hemolytic properties. | [] | null | |
The sequence of AAs AIGSILGALAKGLPTLRSWIKNR exhibits hemolytic properties. | The sequence of AAs AIGSILGALAKGLPTLRSWIKNR exhibits hemolytic properties. | [] | null | |
The sequence of amino acids RWRWWWRWRI exhibits hemolytic properties. | The sequence of amino acids RWRWWWRWRI exhibits hemolytic properties. | [] | null | |
The sequence of amino acids RWCVYAYVRGRGVLVRYRRCW demonstrates hemolytic properties. | The sequence of amino acids RWCVYAYVRGRGVLVRYRRCW demonstrates hemolytic properties. | [] | null | |
The sequence of AAs GLPICGETCVGGTCNTPGCSCSWPVCTRN exhibits hemolytic properties. | The sequence of AAs GLPICGETCVGGTCNTPGCSCSWPVCTRN exhibits hemolytic properties. | [] | null | |
The sequence of AAs IAPWKWPWWPWRR shows hemolytic properties. | The sequence of AAs IAPWKWPWWPWRR shows hemolytic properties. | [] | null | |
The sequence of amino acids KRFKKFFKKLKNSVKKRVKKFFRKPRVIGVTFPF demonstrates hemolytic properties. | The sequence of amino acids KRFKKFFKKLKNSVKKRVKKFFRKPRVIGVTFPF demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids GEILCNLCTGLINTLENLLTTKGADKVKDYISSLCNKASGFIATLCTKVLDFGIDKLIQLIEDKVDANAICAKIHAC exhibits hemolytic properties. | The sequence of amino acids GEILCNLCTGLINTLENLLTTKGADKVKDYISSLCNKASGFIATLCTKVLDFGIDKLIQLIEDKVDANAICAKIHAC exhibits hemolytic properties. | [] | null | |
The sequence of amino acids NAGSLLSGWG demonstrates hemolytic properties. | The sequence of amino acids NAGSLLSGWG demonstrates hemolytic properties. | [] | null | |
The sequence of AAs RIWR exhibits hemolytic properties. | The sequence of AAs RIWR exhibits hemolytic properties. | [] | null | |
The sequence of amino acids KIAKRIWKILRRRLFRRVKKVAG shows hemolytic properties. | The sequence of amino acids KIAKRIWKILRRRLFRRVKKVAG shows hemolytic properties. | [] | null | |
The sequence of amino acids AKRQALTKYLLEELRKRGKKAFIAW demonstrates hemolytic properties. | The sequence of amino acids AKRQALTKYLLEELRKRGKKAFIAW demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids RDAKELVELFFEEIRRAL exhibits hemolytic properties. | The sequence of amino acids RDAKELVELFFEEIRRAL exhibits hemolytic properties. | [] | null | |
The sequence of AAs GRR shows hemolytic properties. | The sequence of AAs GRR shows hemolytic properties. | [] | null | |
The sequence of amino acids FFFLPSLIGGLVSAIK exhibits hemolytic properties. | The sequence of amino acids FFFLPSLIGGLVSAIK exhibits hemolytic properties. | [] | null | |
The sequence of amino acids GFLSILKKVLKVMAHMK demonstrates hemolytic properties. | The sequence of amino acids GFLSILKKVLKVMAHMK demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids KRKLIFLAAFLAALALFKKR shows hemolytic properties. | The sequence of amino acids KRKLIFLAAFLAALALFKKR shows hemolytic properties. | [] | null | |
The sequence of AAs KLPKLLKKLLKLLK demonstrates hemolytic properties. | The sequence of AAs KLPKLLKKLLKLLK demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids LFGMALKLLKKVL shows hemolytic properties. | The sequence of amino acids LFGMALKLLKKVL shows hemolytic properties. | [] | null | |
The sequence of amino acids FLPLIAGLFGKIF demonstrates hemolytic properties. | The sequence of amino acids FLPLIAGLFGKIF demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids ILAWKWPWWPWRR demonstrates hemolytic properties. | The sequence of amino acids ILAWKWPWWPWRR demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids GLPVCGETCFTGSCYTPGCSCNWPVCNRN shows hemolytic properties. | The sequence of amino acids GLPVCGETCFTGSCYTPGCSCNWPVCNRN shows hemolytic properties. | [] | null | |
The sequence of AAs LKKLLKLLKKALKLAG shows hemolytic properties. | The sequence of AAs LKKLLKLLKKALKLAG shows hemolytic properties. | [] | null | |
The sequence of AAs IHKLVKLWLNLGKKF demonstrates hemolytic properties. | The sequence of AAs IHKLVKLWLNLGKKF demonstrates hemolytic properties. | [] | null | |
The sequence of amino acids KVNHAACAAHCLLKRKRGGYCNKRRICVCRN exhibits hemolytic properties. | The sequence of amino acids KVNHAACAAHCLLKRKRGGYCNKRRICVCRN exhibits hemolytic properties. | [] | null | |
The sequence of amino acids GLPVCGETCVGGTCNTPGCTCSWPVCTKN shows hemolytic properties. | The sequence of amino acids GLPVCGETCVGGTCNTPGCTCSWPVCTKN shows hemolytic properties. | [] | null | |
The sequence of AAs FVQWFSKALGRIL exhibits hemolytic properties. | The sequence of AAs FVQWFSKALGRIL exhibits hemolytic properties. | [] | null | |
The sequence of amino acids FLPLLLSALPSFLCLVFKKC shows hemolytic properties. | The sequence of amino acids FLPLLLSALPSFLCLVFKKC shows hemolytic properties. | [] | null | |
The sequence of amino acids HHIIGGLFSAGKAIHRLIRRRRR demonstrates hemolytic properties. | The sequence of amino acids HHIIGGLFSAGKAIHRLIRRRRR demonstrates hemolytic properties. | [] | null | |
The sequence of AAs ILPWKWPWWPWRR shows hemolytic properties. | The sequence of AAs ILPWKWPWWPWRR shows hemolytic properties. | [] | null | |
The sequence of amino acids FFPLVLGALGSILPKIF shows hemolytic properties. | The sequence of amino acids FFPLVLGALGSILPKIF shows hemolytic properties. | [] | null | |
The sequence of AAs WR exhibits hemolytic properties. | The sequence of AAs WR exhibits hemolytic properties. | [] | null |
Dataset Details
Dataset Description
Hemolysis is referred to the disruption of erythrocyte membranes that decrease the life span of red blood cells and causes the release of Hemoglobin. It is critical to identify non-hemolytic antimicrobial peptides as a non-toxic and safe measure against bacterial infections. However, distinguishing between hemolytic and non-hemolytic peptides is a challenge, since they primarily exert their activity at the charged surface of the bacterial plasma membrane. The data here comes from the Database of Antimicrobial Activity and Structure of Peptides (DBAASP v3). Hemolytic activity is defined by extrapolating a measurement assuming dose response curves to the point at which 50% of red blood cells are lysed. Activities below 100 mu g/ml, are considered hemolytic. The data contains sequences of only L- and canonical amino acids. Each measurement is treated independently, so sequences can appear multiple times. This experimental dataset contains noise, and in some observations (40%), an identical sequence appears in both negative and positive class. As an example, sequence "RVKRVWPLVIRTVIAGYNLYRAIKKK" is found to be both hemolytic and non-hemolytic in two different lab experiments (i.e. two different training examples).
- Curated by:
- License: CC BY 4.0
Dataset Sources
Citation
BibTeX:
@article{Martins2012,
doi = {10.1021/ci300124c},
url = {https://doi.org/10.1021/ci300124c},
year = {2012},
month = jun,
publisher = {American Chemical Society (ACS)},
volume = {52},
number = {6},
pages = {1686--1697},
author = {Ines Filipa Martins and Ana L. Teixeira and Luis Pinheiro
and Andre O. Falcao},
title = {A Bayesian Approach to in Silico Blood-Brain Barrier Penetration Modeling},
journal = {Journal of Chemical Information and Modeling}
@article{Wu2018,
doi = {10.1039/c7sc02664a},
url = {https://doi.org/10.1039/c7sc02664a},
year = {2018},
publisher = {Royal Society of Chemistry (RSC)},
volume = {9},
number = {2},
pages = {513--530},
author = {Zhenqin Wu and Bharath Ramsundar and Evan~N. Feinberg and Joseph
Gomes and Caleb Geniesse and Aneesh S. Pappu and Karl Leswing and Vijay Pande},
title = {MoleculeNet: a benchmark for molecular machine learning},
journal = {Chemical Science}
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