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End of preview.

ENCODE ChIP-seq Vetorizado

Saída do pipeline de vetorização do fabricioslv/encode-chip-seq-subset.

3 estratégias

Stage 1 — Bins fixos (10kb)

Matriz densa (n_bins × n_tracks) por cromossomo. Formato: .npz.

Stage 2 — Peak detection (5σ) + embeddings

Picos detectados por threshold estatístico. Embedding de 9 features por pico. Formato: peaks.tsv + embeddings.npz.

Stage 3 — Janelas sliding (10kb, stride 5kb) + DL tensors

Tensores normalizados (z-score) prontos para CNN/Transformer. Formato: .h5.

Parâmetros

  • Bin size: 10000 bp
  • Peak threshold: 5.0σ
  • Window: 10000 bp, stride: 5000 bp
  • Sub-sampling: 100 pontos por janela (Stage 3)
  • Device: cpu
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