Datasets:

einarolafsson
/

spacr-example-control-chart

plate stringclasses 24 values	run_order int64 1 24 ⌀	plate_condition stringclasses 7 values	cell_line stringclasses 2 values	timepoint_h int64 24 48	well stringclasses 384 values	well_type stringclasses 5 values	pert_iname stringclasses 303 values	broad_sample stringclasses 307 values	Cells_Number_Object_Number float64 1 176 ⌀	Cells_AreaShape_Area float64 394 294k ⌀	Nuclei_AreaShape_Area float64 102 1.94k ⌀	Cells_AreaShape_FormFactor float64 0.01 0.93 ⌀	Cells_Intensity_MeanIntensity_DNA float64 0 0.12 ⌀	Cells_Intensity_MeanIntensity_Mito float64 0 0.37 ⌀	Cells_Intensity_MeanIntensity_ER float64 0 0.16 ⌀	Cells_Intensity_MeanIntensity_RNA float64 0.01 0.23 ⌀	Cells_Intensity_MeanIntensity_AGP float64 0 0.21 ⌀	Nuclei_Intensity_IntegratedIntensity_DNA float64 2.16 175 ⌀	Cytoplasm_Granularity_1_Mito float64 15.3 92.8 ⌀
BR00116991	1	A549 24-hour Compound	A549	24	A01	trt	gabapentin-enacarbil	BRD-A86665761-001-01-1	84.691	4,302.6	695.55	0.53783	0.024286	0.054997	0.044066	0.071225	0.065334	64.856	69.011
BR00116991	1	A549 24-hour Compound	A549	24	A02	negcon	DMSO	DMSO	114.01	3,584.8	617.29	0.54316	0.027667	0.043052	0.048182	0.083867	0.068606	62.979	65.071
BR00116991	1	A549 24-hour Compound	A549	24	A03	trt	amlodipine	BRD-A22032524-074-09-9	87.507	4,014.4	581.53	0.52357	0.027221	0.051587	0.049429	0.08187	0.073072	66.294	58.863
BR00116991	1	A549 24-hour Compound	A549	24	A04	trt	hexestrol	BRD-A01078468-001-14-8	99.803	3,554.1	583.02	0.54072	0.029177	0.032825	0.047319	0.082457	0.06676	67.252	66.983
BR00116991	1	A549 24-hour Compound	A549	24	A05	trt	quinine	BRD-K48278478-001-01-2	78.307	3,548.9	428.22	0.47584	0.033284	0.0242	0.040654	0.064468	0.056559	80.604	71.637
BR00116991	1	A549 24-hour Compound	A549	24	A06	trt	LOXO-101	BRD-K36574127-001-01-3	65.898	3,675.1	638.12	0.55071	0.02877	0.026089	0.049978	0.084058	0.076348	69.553	71.675
BR00116991	1	A549 24-hour Compound	A549	24	A07	trt	brinzolamide	BRD-K74913225-001-14-0	87.123	3,757.6	612.64	0.55054	0.029041	0.029238	0.053748	0.089959	0.070782	70.277	68.838
BR00116991	1	A549 24-hour Compound	A549	24	A08	trt	NS-11021	BRD-K94342292-001-01-3	81.73	4,032.4	610.47	0.52594	0.026773	0.027271	0.051959	0.087213	0.066666	69.443	70.538
BR00116991	1	A549 24-hour Compound	A549	24	A09	negcon	DMSO	DMSO	92.191	3,716.2	665.58	0.53775	0.026067	0.03263	0.050827	0.085263	0.065723	62.677	65.114
BR00116991	1	A549 24-hour Compound	A549	24	A10	trt	GNF-5837	BRD-K19975102-001-01-2	77.458	3,954.4	689.55	0.53717	0.024458	0.029989	0.053885	0.092031	0.068549	60.583	61.423
BR00116991	1	A549 24-hour Compound	A549	24	A11	trt	apatinib	BRD-K25244359-066-02-6	73.113	3,477.8	684.26	0.53973	0.026531	0.036429	0.059641	0.098005	0.074628	59.916	62.22
BR00116991	1	A549 24-hour Compound	A549	24	A12	trt	ethoxzolamide	BRD-K18131774-001-18-4	88.158	3,852.8	707.26	0.53936	0.025611	0.035926	0.053081	0.087324	0.062297	61.449	64.828
BR00116991	1	A549 24-hour Compound	A549	24	A13	trt	ascorbic-acid	BRD-A85242401-001-11-5	74.392	3,790.7	698.88	0.51964	0.025359	0.033641	0.055608	0.089092	0.062953	61.709	64.349
BR00116991	1	A549 24-hour Compound	A549	24	A14	trt	ryuvidine	BRD-K06426971-001-02-7	22.956	3,774.3	742.16	0.56372	0.035927	0.035424	0.056605	0.090328	0.079711	79.533	57.583
BR00116991	1	A549 24-hour Compound	A549	24	A15	trt	BAN-ORL-24	BRD-K47049295-300-03-1	47.589	3,980.3	739.87	0.58877	0.025679	0.033576	0.063819	0.10237	0.081564	63.21	60.034
BR00116991	1	A549 24-hour Compound	A549	24	A16	trt	NNC-55-0396	BRD-K78122587-300-04-3	51.626	4,227.6	684.68	0.51777	0.021845	0.03358	0.065498	0.11901	0.086167	55.79	56.749
BR00116991	1	A549 24-hour Compound	A549	24	A17	negcon	DMSO	DMSO	72.099	3,920.8	712.79	0.54894	0.02588	0.026496	0.057331	0.093542	0.065588	64.065	65.907
BR00116991	1	A549 24-hour Compound	A549	24	A18	trt	WH-4-023	BRD-K50199947-001-03-4	53.682	2,871	703.35	0.54506	0.032685	0.035901	0.086641	0.13617	0.10709	63.253	57.659
BR00116991	1	A549 24-hour Compound	A549	24	A19	trt	flupirtine	BRD-K50720187-051-03-1	62.604	4,325.8	741.49	0.53534	0.024901	0.02145	0.052651	0.086516	0.062991	66.873	63.873
BR00116991	1	A549 24-hour Compound	A549	24	A20	trt	ZK811752	BRD-K91825936-001-03-9	69.429	3,666.1	702.78	0.53467	0.027115	0.021281	0.061302	0.097308	0.071185	63.787	64.873
BR00116991	1	A549 24-hour Compound	A549	24	A21	trt	dexamethasone	BRD-K38775274-001-22-1	71.53	4,792.7	711.73	0.55063	0.022173	0.018111	0.051623	0.085479	0.059393	61.206	72.106
BR00116991	1	A549 24-hour Compound	A549	24	A22	trt	PP-1	BRD-K47598052-001-14-1	60.331	2,363.4	684.5	0.59119	0.038353	0.02205	0.08682	0.1439	0.10065	67.724	65.222
BR00116991	1	A549 24-hour Compound	A549	24	A23	trt	DDR1-IN-1	BRD-K61845293-300-01-9	62.541	4,135	699.61	0.52685	0.021214	0.017434	0.05721	0.090854	0.06967	55.093	62.65
BR00116991	1	A549 24-hour Compound	A549	24	A24	trt	AVL-292	BRD-K87782578-001-01-4	49.894	3,110.3	726.24	0.56717	0.029289	0.016958	0.071355	0.1134	0.088527	61.303	64.47
BR00116991	1	A549 24-hour Compound	A549	24	B01	trt	H2L-5765834	BRD-K26439554-001-01-3	102.34	3,682.4	697.61	0.55437	0.025135	0.071932	0.056579	0.11135	0.070123	57.792	60.369
BR00116991	1	A549 24-hour Compound	A549	24	B02	trt	thiostrepton	BRD-K58049875-001-03-9	74.697	3,422.3	680.71	0.58529	0.026151	0.068674	0.069328	0.13226	0.094315	57.719	50.955
BR00116991	1	A549 24-hour Compound	A549	24	B03	negcon	DMSO	DMSO	94.619	3,368.7	690.36	0.55009	0.027095	0.059024	0.058943	0.11135	0.067824	59.547	59.725
BR00116991	1	A549 24-hour Compound	A549	24	B04	trt	arcyriaflavin-a	BRD-K72726508-001-02-1	79.684	4,101.8	757.05	0.52729	0.021396	0.052099	0.056357	0.11115	0.071322	52.625	66.083
BR00116991	1	A549 24-hour Compound	A549	24	B05	trt	CYM-5520	BRD-K29151923-001-01-5	85.704	3,448.6	683.23	0.55257	0.026212	0.051496	0.059129	0.11003	0.07344	57.996	59.008
BR00116991	1	A549 24-hour Compound	A549	24	B06	trt	fludarabine	BRD-K66788707-001-14-3	61.717	4,862	789.8	0.54024	0.021182	0.052087	0.055682	0.10532	0.067986	60.313	60.391
BR00116991	1	A549 24-hour Compound	A549	24	B07	trt	alda-1	BRD-K06890060-001-09-1	75.882	3,783.7	705.07	0.54866	0.025615	0.052277	0.059312	0.10767	0.069296	61.824	59.387
BR00116991	1	A549 24-hour Compound	A549	24	B08	trt	meclofenamic-acid	BRD-K50398167-236-22-7	86.441	3,632.2	678.46	0.55585	0.026238	0.053712	0.05973	0.1107	0.067773	59.086	59.241
BR00116991	1	A549 24-hour Compound	A549	24	B09	trt	GNF-5	BRD-K87632963-001-03-0	76.959	4,438.2	694.79	0.52741	0.023	0.047401	0.050605	0.094403	0.062137	62.214	60.348
BR00116991	1	A549 24-hour Compound	A549	24	B10	trt	NS-309	BRD-K37602296-001-01-6	84.506	3,231.8	682.58	0.5578	0.028047	0.048265	0.062325	0.11174	0.071923	60.008	58.914
BR00116991	1	A549 24-hour Compound	A549	24	B11	trt	AK-7	BRD-K09143580-001-01-0	72.995	3,525.1	673.07	0.54777	0.025772	0.046312	0.057732	0.10148	0.071892	56.924	58.715
BR00116991	1	A549 24-hour Compound	A549	24	B12	trt	BVT-948	BRD-A22713669-001-04-3	76.025	3,293.3	686.61	0.55604	0.027759	0.045978	0.059035	0.10733	0.069099	60.09	57.908
BR00116991	1	A549 24-hour Compound	A549	24	B13	trt	SirReal-2	BRD-K16472653-001-01-6	69.412	3,489	695.68	0.5538	0.026595	0.040373	0.059847	0.10587	0.06984	59.328	60.226
BR00116991	1	A549 24-hour Compound	A549	24	B14	negcon	DMSO	DMSO	81.79	3,706.6	694.04	0.5475	0.024831	0.031116	0.057403	0.09842	0.064154	57.444	62.39
BR00116991	1	A549 24-hour Compound	A549	24	B15	trt	BMS-536924	BRD-K34581968-001-05-3	47.228	2,669.5	736.4	0.57122	0.035579	0.037325	0.082198	0.13946	0.10333	67.739	56.088
BR00116991	1	A549 24-hour Compound	A549	24	B16	trt	PP-121	BRD-K81801188-001-02-8	33.867	1,874.4	607.54	0.5814	0.045546	0.035059	0.09467	0.16243	0.12766	66.856	39.733
BR00116991	1	A549 24-hour Compound	A549	24	B17	trt	MCOPPB	BRD-K73276278-305-01-1	75.58	3,509.2	682.99	0.55602	0.026422	0.023021	0.068113	0.11545	0.084999	60.567	57.83
BR00116991	1	A549 24-hour Compound	A549	24	B18	trt	ozagrel	BRD-K53061490-003-13-9	77.326	3,566.4	699.06	0.56528	0.027367	0.016552	0.060467	0.10962	0.068505	63.01	65.88
BR00116991	1	A549 24-hour Compound	A549	24	B19	trt	CYM-5442	BRD-A43005764-003-01-5	61.931	3,944.1	710.39	0.55792	0.024748	0.015066	0.061229	0.10528	0.07145	62.243	64.135
BR00116991	1	A549 24-hour Compound	A549	24	B20	trt	CVT-10216	BRD-K60659193-001-01-0	77.122	3,588	696.99	0.55091	0.025348	0.011939	0.057627	0.095634	0.064572	59.799	69.084
BR00116991	1	A549 24-hour Compound	A549	24	B21	trt	TCN201	BRD-K09787262-001-02-7	92.491	3,350	685.88	0.56921	0.027221	0.010769	0.060634	0.10044	0.069128	59.034	70.592
BR00116991	1	A549 24-hour Compound	A549	24	B22	trt	fomepizole	BRD-K56810756-003-07-7	83.269	3,379.6	687.57	0.56925	0.02908	0.011893	0.062218	0.10837	0.070862	65.463	69.44
BR00116991	1	A549 24-hour Compound	A549	24	B23	trt	benzamil	BRD-K87158025-003-08-7	73.544	3,710.5	701.64	0.55599	0.02712	0.01201	0.058146	0.10024	0.067627	65.069	70.092
BR00116991	1	A549 24-hour Compound	A549	24	B24	trt	lercanidipine	BRD-A18992208-003-02-7	68.5	3,553.1	689.39	0.55391	0.026112	0.013766	0.061791	0.1038	0.074857	59.247	68.693
BR00116991	1	A549 24-hour Compound	A549	24	C01	trt	4-CMTB	BRD-A54139254-001-09-2	109.94	3,391.8	631.07	0.5496	0.0283	0.057484	0.049226	0.08127	0.066547	62.091	64.403
BR00116991	1	A549 24-hour Compound	A549	24	C02	trt	ML-228	BRD-K44432556-001-05-5	90.419	3,517.6	592.24	0.55209	0.029753	0.045131	0.049112	0.084265	0.066651	67.36	63.094
BR00116991	1	A549 24-hour Compound	A549	24	C03	negcon	DMSO	DMSO	101.9	3,335.2	570.52	0.53607	0.029557	0.046264	0.04966	0.081124	0.066902	64.747	61.269
BR00116991	1	A549 24-hour Compound	A549	24	C04	trt	GSK1070916	BRD-K36740062-001-06-6	49.845	3,932	751.6	0.52549	0.036415	0.04916	0.070232	0.11791	0.09846	90.366	58.921
BR00116991	1	A549 24-hour Compound	A549	24	C05	trt	ML-193	BRD-K27539181-001-08-5	85.776	3,226.7	587.41	0.55831	0.030729	0.030372	0.053714	0.091171	0.072669	67.076	66.289
BR00116991	1	A549 24-hour Compound	A549	24	C06	negcon	DMSO	DMSO	82.341	3,593.5	622.17	0.55779	0.027943	0.03081	0.0523	0.088138	0.068652	65.47	67.128
BR00116991	1	A549 24-hour Compound	A549	24	C07	trt	M-25	BRD-K51265828-001-01-0	93.772	3,639.6	619.28	0.5445	0.026996	0.032617	0.04947	0.08211	0.062579	63.929	65.795
BR00116991	1	A549 24-hour Compound	A549	24	C08	trt	azeliragon	BRD-K51899933-001-02-6	61.51	2,989.8	549.01	0.55256	0.031649	0.034369	0.079047	0.13181	0.10147	63.956	46.818
BR00116991	1	A549 24-hour Compound	A549	24	C09	poscon_diverse	CYT-997	BRD-K23363278-001-02-1	15.405	3,826.8	667.37	0.59501	0.049345	0.027026	0.066263	0.099371	0.083893	132.94	72.31
BR00116991	1	A549 24-hour Compound	A549	24	C10	trt	AR-12	BRD-K90497590-001-05-9	18.429	2,175.1	415.84	0.51781	0.050188	0.045195	0.05494	0.072809	0.056203	86.241	50.908
BR00116991	1	A549 24-hour Compound	A549	24	C11	trt	CYM-50260	BRD-K69877120-001-01-7	81.085	3,649.1	693.7	0.55581	0.027164	0.038778	0.060263	0.095988	0.067027	63.413	64.027
BR00116991	1	A549 24-hour Compound	A549	24	C12	negcon	DMSO	DMSO	81.376	3,529.3	682	0.55171	0.029643	0.042601	0.068706	0.12458	0.069946	68.775	62.5
BR00116991	1	A549 24-hour Compound	A549	24	C13	poscon_cp	KG-5	BRD-K90747162-001-01-4	26.621	4,056.2	887	0.69132	0.03957	0.045488	0.086944	0.13942	0.10321	103.93	58.583
BR00116991	1	A549 24-hour Compound	A549	24	C14	trt	JTE-607	BRD-K81405859-300-01-4	68.528	4,440.8	768.31	0.53501	0.022529	0.035516	0.057805	0.088965	0.063108	62.56	66.477
BR00116991	1	A549 24-hour Compound	A549	24	C15	negcon	DMSO	DMSO	70.197	3,508.2	687.35	0.55154	0.027181	0.033219	0.060888	0.097088	0.067954	62.117	61.989
BR00116991	1	A549 24-hour Compound	A549	24	C16	trt	ilomastat	BRD-K51662849-001-05-4	80.003	3,703	709.23	0.54048	0.026811	0.032273	0.062432	0.10059	0.067096	62.864	65.045
BR00116991	1	A549 24-hour Compound	A549	24	C17	trt	RX-821002	BRD-A65597028-003-08-1	76.896	3,680.7	701.13	0.5422	0.02663	0.029038	0.05783	0.095255	0.06569	63.034	63.136
BR00116991	1	A549 24-hour Compound	A549	24	C18	negcon	DMSO	DMSO	76.645	3,697.5	702.08	0.55668	0.028127	0.028176	0.060942	0.10411	0.068605	66.216	64.269
BR00116991	1	A549 24-hour Compound	A549	24	C19	trt	TUG-891	BRD-K24282351-001-01-4	69.914	3,677.8	696.92	0.55513	0.025553	0.024672	0.057955	0.090661	0.065287	60.055	64.518
BR00116991	1	A549 24-hour Compound	A549	24	C20	trt	ponatinib	BRD-K44227013-001-08-0	15.473	2,037	630.37	0.65612	0.042207	0.040459	0.077676	0.1007	0.081636	72.51	62.843
BR00116991	1	A549 24-hour Compound	A549	24	C21	negcon	DMSO	DMSO	82.594	3,462.6	677.36	0.5549	0.029007	0.021732	0.060162	0.10297	0.067557	64.955	66.109
BR00116991	1	A549 24-hour Compound	A549	24	C22	trt	puromycin	BRD-K01824976-300-02-9	26.485	2,070.8	600.02	0.71012	0.041874	0.041968	0.079644	0.12693	0.081667	60.696	52.847
BR00116991	1	A549 24-hour Compound	A549	24	C23	trt	SRC-kinase-inhibitor-I	BRD-K50495309-001-02-0	55.049	3,489.7	719.14	0.56132	0.029084	0.017026	0.06612	0.11444	0.076989	67.904	68.251
BR00116991	1	A549 24-hour Compound	A549	24	C24	trt	acetylcysteine	BRD-K59058747-001-19-1	88.043	3,599.1	692.45	0.55845	0.028037	0.014863	0.063588	0.1084	0.067872	65.343	69.133
BR00116991	1	A549 24-hour Compound	A549	24	D01	trt	NSC-625987	BRD-K62949423-001-03-1	111.47	3,590.1	680.14	0.55229	0.024542	0.058678	0.057167	0.1084	0.069421	55.229	61.715
BR00116991	1	A549 24-hour Compound	A549	24	D02	trt	dalfampridine	BRD-K22482860-001-20-6	108.97	3,214	656.9	0.55675	0.027464	0.064195	0.063009	0.12139	0.072991	56.06	59.494
BR00116991	1	A549 24-hour Compound	A549	24	D03	trt	NSC-95397	BRD-K68143200-001-11-7	94.163	3,342.1	686.76	0.55718	0.027587	0.055477	0.067943	0.12791	0.077442	58.193	56.656
BR00116991	1	A549 24-hour Compound	A549	24	D04	trt	alrestatin	BRD-K35498378-001-06-1	107.39	3,348.1	658.03	0.5588	0.027301	0.054822	0.06324	0.1273	0.071262	58.187	59.498
BR00116991	1	A549 24-hour Compound	A549	24	D05	poscon_diverse	PF-03758309	BRD-K37764012-001-03-3	90.14	3,390.7	677.54	0.55957	0.025752	0.050015	0.058956	0.10868	0.067782	57.599	60.544
BR00116991	1	A549 24-hour Compound	A549	24	D06	trt	IRL-2500	BRD-K98357249-001-02-9	85.864	3,516.7	685.38	0.54735	0.025996	0.053618	0.061164	0.11558	0.072996	59.575	59.247
BR00116991	1	A549 24-hour Compound	A549	24	D07	poscon_cp	PF-04217903	BRD-K73319509-001-08-0	84.297	3,402.1	661.55	0.5599	0.02726	0.05132	0.062517	0.11947	0.072803	59.117	57.309
BR00116991	1	A549 24-hour Compound	A549	24	D08	poscon_diverse	FK-866	BRD-K58550667-001-08-7	91.453	3,563.7	684.71	0.55155	0.0264	0.048334	0.060391	0.11399	0.068851	60.253	61.615
BR00116991	1	A549 24-hour Compound	A549	24	D09	trt	amlexanox	BRD-K29530284-001-06-2	73.995	3,637.1	682.68	0.56383	0.026268	0.047263	0.062045	0.11908	0.069681	60.652	58.097
BR00116991	1	A549 24-hour Compound	A549	24	D10	trt	GW-311616	BRD-K37864785-001-01-0	83.973	3,389.2	684.37	0.54611	0.027687	0.044298	0.065065	0.12262	0.073088	60.965	60.411
BR00116991	1	A549 24-hour Compound	A549	24	D11	poscon_diverse	buparlisib	BRD-K42191735-001-08-7	31.533	3,044	695.69	0.68872	0.038503	0.052656	0.078636	0.13742	0.092261	80.901	50.441
BR00116991	1	A549 24-hour Compound	A549	24	D12	trt	amiloride	BRD-K97181089-003-24-7	83.457	3,193.7	678.03	0.56469	0.03075	0.043314	0.068066	0.13423	0.074119	65.026	61.22
BR00116991	1	A549 24-hour Compound	A549	24	D13	trt	DG-172	BRD-K75748943-300-01-3	79.747	3,355.3	690.93	0.55381	0.027741	0.042792	0.06936	0.12216	0.074348	61.188	58.527
BR00116991	1	A549 24-hour Compound	A549	24	D14	negcon	DMSO	DMSO	70.62	3,614.8	706.06	0.54818	0.025851	0.033036	0.060352	0.10463	0.068253	60.508	61.932
BR00116991	1	A549 24-hour Compound	A549	24	D15	negcon	DMSO	DMSO	87.152	3,503.3	687.29	0.54471	0.026324	0.03384	0.058978	0.10528	0.065902	60.429	61.004
BR00116991	1	A549 24-hour Compound	A549	24	D16	poscon_cp	NVP-ADW742	BRD-K15179513-001-04-2	41.5	2,856.4	626.18	0.60831	0.030459	0.043815	0.082527	0.14278	0.11601	58.217	43.073
BR00116991	1	A549 24-hour Compound	A549	24	D17	trt	misoprostol	BRD-A72351335-001-04-5	79.172	3,855.2	700.91	0.55194	0.024933	0.028392	0.05661	0.10256	0.064807	61.843	61.624
BR00116991	1	A549 24-hour Compound	A549	24	D18	trt	conivaptan	BRD-K37385792-003-02-1	66.609	3,906.1	699.74	0.54265	0.024704	0.025453	0.05963	0.10565	0.070531	61.505	60.974
BR00116991	1	A549 24-hour Compound	A549	24	D19	trt	spiroxatrine	BRD-A72483914-001-03-7	75.919	3,699.7	706.41	0.5461	0.025317	0.019674	0.058347	0.098749	0.069349	61.043	64.17
BR00116991	1	A549 24-hour Compound	A549	24	D20	trt	diacerein	BRD-K69122748-001-10-1	65.329	3,522.6	681.36	0.54607	0.025916	0.015437	0.058878	0.10145	0.071358	59.728	65.369
BR00116991	1	A549 24-hour Compound	A549	24	D21	negcon	DMSO	DMSO	75.521	3,605.2	695.51	0.5608	0.027353	0.013126	0.059209	0.10408	0.067751	65.453	66.537
BR00116991	1	A549 24-hour Compound	A549	24	D22	negcon	DMSO	DMSO	84.976	3,530.5	682.69	0.56379	0.027009	0.01249	0.05961	0.10074	0.066438	61.11	68.185
BR00116991	1	A549 24-hour Compound	A549	24	D23	trt	glyburide	BRD-K36927236-001-36-7	83.705	3,574.6	702.76	0.5588	0.02605	0.012025	0.059437	0.095587	0.067354	60.124	70.234
BR00116991	1	A549 24-hour Compound	A549	24	D24	trt	ANR-94	BRD-K31170746-001-01-6	73.712	3,666.1	702.38	0.54322	0.028165	0.013462	0.06089	0.10913	0.066978	68.513	69.175
BR00116991	1	A549 24-hour Compound	A549	24	E01	trt	TFC-007	BRD-K57708067-001-01-3	116.34	3,371.9	611.54	0.55272	0.02812	0.068031	0.04571	0.078302	0.06081	61.827	59.475
BR00116991	1	A549 24-hour Compound	A549	24	E02	trt	trihexyphenidyl	BRD-A48180038-003-24-3	103.3	3,441.3	571.13	0.54761	0.029862	0.046757	0.051379	0.088089	0.069814	66.251	63.609
BR00116991	1	A549 24-hour Compound	A549	24	E03	trt	epoprostenol	BRD-K64054020-001-02-7	87.606	3,411.4	605.25	0.54299	0.029598	0.050295	0.051891	0.085915	0.072343	67.421	61.796
BR00116991	1	A549 24-hour Compound	A549	24	E04	trt	sacubitril	BRD-K91456750-001-01-9	100.93	3,564	578.18	0.54114	0.02942	0.037208	0.049058	0.085708	0.067349	67.742	65.111

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spaCR — Control Chart example (CPJUMP1)

Well-level Cell Painting profiles of the 24 compound plates of the CPJUMP1 pilot, cut to plate, well and control metadata and eleven CellProfiler features. It is the data behind Load test data… on spaCR's Control Chart screen (an alpha feature): the screen opens control_chart_wells.csv, charts the DMSO negative-control wells plate by plate, and marks the plates whose controls drift outside the limits.

9,131 wells, 1,586 kB as spacr-example-control-chart.tar (one uncompressed tar, what spaCR downloads) and the same table loose as control_chart_wells.csv.

Source

Cell Painting Gallery cpg0000-jump-pilot, source_4, batch 2020_11_04_CPJUMP1, file workspace/profiles/2020_11_04_CPJUMP1/<plate>/<plate>_augmented.csv.gz (median-aggregated, well-level CellProfiler profiles).
Plates: BR00116991, BR00116992, BR00116993, BR00116994, BR00116995, BR00117008, BR00117009, BR00117010, BR00117011, BR00117012, BR00117013, BR00117015, BR00117016, BR00117017, BR00117019, BR00117024, BR00117025, BR00117026, BR00117050, BR00117051, BR00117052, BR00117053, BR00117054, BR00117055.
Plate conditions (plates.csv) from the CPJUMP1 paper's experiment metadata, benchmark/input/2020_11_04_CPJUMP1.csv in jump-cellpainting/2024_Chandrasekaran_NatureMethods_CPJUMP1.

Columns

control_chart_wells.csv: plate, run_order (rank of the plate barcode, 1 = lowest; the barcode order, not a recorded acquisition time), plate_condition, cell_line, timepoint_h, well, well_type (negcon = DMSO, poscon_cp, poscon_diverse, poscon_orf, trt), pert_iname, broad_sample, then the features Cells_Number_Object_Number, Cells_AreaShape_Area, Nuclei_AreaShape_Area, Cells_AreaShape_FormFactor, Cells_Intensity_MeanIntensity_DNA, Cells_Intensity_MeanIntensity_Mito, Cells_Intensity_MeanIntensity_ER, Cells_Intensity_MeanIntensity_RNA, Cells_Intensity_MeanIntensity_AGP, Nuclei_Intensity_IntegratedIntensity_DNA, Cytoplasm_Granularity_1_Mito. Cells_Number_Object_Number is CellProfiler's median object number per well, which rises with the number of cells in a field.

The plates mix two cell lines, two time points and three seeding densities, so a chart of every plate shows those design changes as shifts. Filter on plate_condition to chart one condition.

Licence and citation

CC0 1.0, as the Cell Painting Gallery publishes it. Please cite:

Chandrasekaran SN, Cimini BA, Goodale A, et al. Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations. Nature Methods 21, 1114–1121 (2024). doi:10.1038/s41592-024-02241-6
Weisbart E, Kumar A, Arevalo J, et al. Cell Painting Gallery: an open resource for image-based profiling. Nature Methods 21, 1775–1777 (2024). doi:10.1038/s41592-024-02399-z

Built by tools/build_control_chart_example_dataset.py in spaCR.

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