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Parse 10K PBMC Cytokines (IFN-γ vs PBS)
Balanced 10,000-cell subsample of the ~10 million cell cytokine stimulation dataset from Parse Biosciences.
In the original experiment, peripheral blood mononuclear cells (PBMCs) from twelve healthy donors were treated with either one of 90 different cytokines or a phosphate-buffered saline (PBS) control for 24 hours, yielding (90 + 1) × 12 = 1,092 experimental conditions.
For the brisc test suite, the data is restricted to the interferon-gamma
(IFN-γ) versus PBS contrast and subsampled to 5,000 cells per condition,
stratified by cell type. The result is 10,000 cells × 40,352 genes of raw
counts across 24 samples (12 donors × 2 conditions) and 18 annotated cell
types, with obs columns sample, donor, cell_type, treatment, and
cytokine.
Source
- https://www.parsebiosciences.com/datasets/10-million-human-pbmcs-in-a-single-experiment/
- https://www.biorxiv.org/content/10.64898/2025.12.12.693897v1
All credit to Parse Biosciences.
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