# EDGAR Filing Document

**Accession Number:** 0001039803
**File Stem:** 0001752724-23-041183
**Filing Date:** 2023-2
**Character Count:** 22005
**Document Hash:** c72b2311bad074f47eb6625a4025afca
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-23-041183.hdr.sgml**: 20230227

**ACCESSION NUMBER**: 0001752724-23-041183

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230227

**DATE AS OF CHANGE**: 20230227

**PERIOD START**: 20221231

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ProFunds
- **CENTRAL INDEX KEY:** 0001039803
- **IRS NUMBER:** 522035197
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-08239
- **FILM NUMBER:** 23670975

**BUSINESS ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814
- **BUSINESS PHONE:** 2404976428

**MAIL ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PROFUNDS
- **DATE OF NAME CHANGE:** 19970521

## Series and Classes Contracts Data

### PROFUND VP PHARMACEUTICALS (Series ID: S000003975)

| Class ID   | Class Name                 | Ticker Symbol   |
|:---|:---|:---|
| C000011102 | PROFUND VP PHARMACEUTICALS |  |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ProFunds

- **b. Investment Company Act file number:** 811-08239

- **c. CIK number of Registrant:** 0001039803

- **d. LEI of Registrant:** 549300HM4OOUYSE5DP77

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 7272 Wisconsin Avenue

  - **City:** Bethesda

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 20814

  - **Telephone number:** 240-497-6400

**Item A.2. Information about the Series.**

- **a. Name of Series:** ProFund VP Pharmaceuticals

- **b. EDGAR series identifier (if any):** S000003975

- **c. LEI of Series:** 0NO8WMNO78H6WEYS4K25

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2022-12-31

- **b. Date as of which information is reported:** 2022-12-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $13622172.43

**Total Liabilities:** $101600.16

**Net Assets:** $13520572.27

**Cash Not Reported:** $220028.00

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000011102 | 6.77%                | 3.60%                | -0.27%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $67057.74                | $735570.55                                 |
| Month 2  | $13168.48                | $400349.89                                 |
| Month 3  | $615518.83               | $-636418.28                                |

**Designated Index Information**

- **Index Name:** Dow Jones U.S. Select Pharmaceuticals Index

- **Index Identifier:** DJSPHM

### Schedule of Portfolio Investments

| Name                                        | Title                                                                                | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| AMPHASTAR PHARMACEUTICALS INC               | AMPHASTAR PHARMACEUTICALS INC                                                        | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |      2105 | NS      | $58982.10     | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Ventyx Biosciences Inc                      | VENTYX BIOSCIENCES INC                                                               | CUSIP: 92332V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1550 | NS      | $50824.50     | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| CATALYST PHARMACEUTICALS, INC.              | CATALYST PHARMACEUTICALS INC                                                         | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |      5348 | NS      | $99472.80     | 0.74%             |  |  |  | No            |                  1 | On Loan: No      |
| Pliant Therapeutics Inc                     | PLIANT THERAPEUTICS INC                                                              | CUSIP: 729139105<br>LEI: 5493002Q5LITR7VHZH02 | Long             | EC               | CORP              | US        |      1879 | NS      | $36321.07     | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| JAZZ PHARMACEUTICALS PUBLIC LIMITED COMPANY | JAZZ PHARMACEUTICALS PLC                                                             | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | IE        |      3516 | NS      | $560133.96    | 4.14%             |  |  |  | No            |                  1 | On Loan: No      |
| CATALENT, INC.                              | CATALENT INC                                                                         | CUSIP: 148806102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10049 | NS      | $452305.49    | 3.35%             |  |  |  | No            |                  1 | On Loan: No      |
| ELI LILLY AND COMPANY                       | ELI LILLY CO                                                                         | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |      6801 | NS      | $2488077.84   | 18.40%            |  |  |  | No            |                  1 | On Loan: No      |
| CASSAVA SCIENCES, INC.                      | CASSAVA SCIENCES INC                                                                 | CUSIP: 14817C107<br>LEI: 529900XA0UG5JXABYF08 | Long             | EC               | CORP              | US        |      2102 | NS      | $62093.08     | 0.46%             |  |  |  | No            |                  1 | On Loan: —       |
| SOCIETE GENERALE                            | SOCIETE GENERALE                                                                     | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |      3000 | PA      | $3000.00      | 0.02%             |  |  |  | No            |                  2 | On Loan: No      |
| REATA PHARMACEUTICALS, INC.                 | REATA PHARMACEUTICALS INC                                                            | CUSIP: 75615P103<br>LEI: 5299005F094GH9QDDD80 | Long             | EC               | CORP              | US        |      1559 | NS      | $59226.41     | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| PFIZER INC.                                 | PFIZER INC                                                                           | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |     11946 | NS      | $612113.04    | 4.53%             |  |  |  | No            |                  1 | On Loan: No      |
| PERRIGO COMPANY PUBLIC LIMITED COMPANY      | PERRIGO CO PLC                                                                       | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | IE        |      7518 | NS      | $256288.62    | 1.90%             |  |  |  | No            |                  1 | On Loan: No      |
| IRONWOOD PHARMACEUTICALS, INC.              | IRONWOOD PHARMACEUTICALS INC                                                         | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |      7452 | NS      | $92330.28     | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| ROYALTY PHARMA PLC                          | ROYALTY PHARMA PLC                                                                   | CUSIP: G7709Q104<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |     14246 | NS      | $563001.92    | 4.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Amylyx Pharmaceuticals Inc                  | AMYLYX PHARMACEUTICALS INC                                                           | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2220 | NS      | $82029.00     | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| ORGANON & CO.                               | ORGANON CO                                                                           | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |     14203 | NS      | $396689.79    | 2.93%             |  |  |  | No            |                  1 | On Loan: No      |
| ROYAL BANK OF CANADA                        | ROYAL BANK OF CANADA                                                                 | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |      1000 | PA      | $1000.00      | 0.01%             |  |  |  | No            |                  2 | On Loan: No      |
| Collegium Pharmaceutical, Inc.              | COLLEGIUM PHARMACEUTICAL INC                                                         | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |      1875 | NS      | $43500.00     | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Dice Therapeutics Inc                       | DICE THERAPEUTICS INC                                                                | CUSIP: 23345J104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1890 | NS      | $58968.00     | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| PACIRA BIOSCIENCES, INC.                    | PACIRA BIOSCIENCES INC                                                               | CUSIP: 695127100<br>LEI: 549300P56LERYBDHCF69 | Long             | EC               | CORP              | US        |      2562 | NS      | $98918.82     | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| ELANCO ANIMAL HEALTH INCORPORATED           | ELANCO ANIMAL HEALTH INC                                                             | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |     24890 | NS      | $304155.80    | 2.25%             |  |  |  | No            |                  1 | On Loan: No      |
| PRESTIGE CONSUMER HEALTHCARE INC.           | PRESTIGE CONSUMER HEALTHCARE INC                                                     | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2765 | NS      | $173089.00    | 1.28%             |  |  |  | No            |                  1 | On Loan: No      |
| AMICUS THERAPEUTICS, INC.                   | AMICUS THERAPEUTICS INC                                                              | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |     13962 | NS      | $170476.02    | 1.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                                 | ARVINAS INC                                                                          | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2705 | NS      | $92538.05     | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| Atea Pharmaceuticals Inc                    | ATEA PHARMACEUTICALS INC                                                             | CUSIP: 04683R106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4232 | NS      | $20355.92     | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Intra-Cellular Therapies Inc                | INTRA CELLULAR THERAPIES INC                                                         | CUSIP: 46116X101<br>LEI: 5299002U2KGF193IJA20 | Long             | EC               | CORP              | US        |      4919 | NS      | $260313.48    | 1.93%             |  |  |  | No            |                  1 | On Loan: No      |
| REVANCE THERAPEUTICS, INC.                  | REVANCE THERAPEUTICS INC                                                             | CUSIP: 761330109<br>LEI: 549300N33TFDZHS81H11 | Long             | EC               | CORP              | US        |      4594 | NS      | $84805.24     | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| VANDA PHARMACEUTICALS INC.                  | VANDA PHARMACEUTICALS INC                                                            | CUSIP: 921659108<br>LEI: 529900AY8VOOQBKJ0O70 | Long             | EC               | CORP              | US        |      3160 | NS      | $23352.40     | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| LIGAND PHARMACEUTICALS INCORPORATED         | LIGAND PHARMACEUTICALS                                                               | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |       896 | NS      | $59852.80     | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| MERCK & CO., INC.                           | MERCK COMPANY INC                                                                    | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |      5452 | NS      | $604899.40    | 4.47%             |  |  |  | No            |                  1 | On Loan: No      |
| THERAVANCE BIOPHARMA, INC.                  | THERAVANCE BIOPHARMA INC                                                             | CUSIP: G8807B106<br>LEI: 5493007VTSXP4Z6MIW52 | Long             | EC               | CORP              | KY        |      3229 | NS      | $36229.38     | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| AXSOME THERAPEUTICS, INC.                   | AXSOME THERAPEUTICS INC                                                              | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |      1916 | NS      | $147781.08    | 1.09%             |  |  |  | No            |                  1 | On Loan: No      |
| PHIBRO ANIMAL HEALTH CORPORATION            | PHIBRO ANIMAL HEALTH CORP                                                            | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |      1136 | NS      | $15233.76     | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| INNOVIVA, INC.                              | INNOVIVA INC                                                                         | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |      3507 | NS      | $46467.75     | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| ZOETIS INC.                                 | ZOETIS INC                                                                           | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |      3995 | NS      | $585467.25    | 4.33%             |  |  |  | No            |                  1 | On Loan: No      |
| AGPXX                                       | Invesco Government & Agency Portfolio                                                | CUSIP: 825252885<br>LEI: N/A                  | N/A              | STIV             | RF                | US        |     62505 | NS      | $62504.75     | 0.46%             |  |  |  | No            |                  1 | On Loan: No      |
| MADRIGAL PHARMACEUTICALS, INC.              | MADRIGAL PHARMACEUTICALS INC                                                         | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |       678 | NS      | $196789.50    | 1.46%             |  |  |  | No            |                  1 | On Loan: No      |
| BRISTOL-MYERS SQUIBB COMPANY                | BRISTOL MYERS SQUIBB CO                                                              | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |      7509 | NS      | $540272.55    | 4.00%             |  |  |  | No            |                  1 | On Loan: No      |
| TOTAL RETURN SWAP AGREEMENT BASED ON THE    | TOTAL RETURN SWAP AGREEMENT BASED ON THE DOW JONES U.S. SELECT PHARMACEUTICALS INDEX | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |        18 | OU      | $-641.27      | -0.00%            |  |  |  | No            |                  2 | On Loan: No      |
| UMB FINANCIAL CORP                          | UMB FINANCIAL CORP                                                                   | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |      3000 | PA      | $3000.00      | 0.02%             |  |  |  | No            |                  2 | On Loan: No      |
| Nuvation Bio Inc                            | NUVATION BIO INC                                                                     | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7647 | NS      | $14682.24     | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Cara Therapeutics Inc                       | CARA THERAPEUTICS INC                                                                | CUSIP: 140755109<br>LEI: 549300COVOY41P0GZ881 | Long             | EC               | CORP              | US        |      2520 | NS      | $27064.80     | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings Inc            | HARMONY BIOSCIENCES HOLDINGS INC                                                     | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1656 | NS      | $91245.60     | 0.67%             |  |  |  | No            |                  1 | On Loan: No      |
| CREDIT AGRICOLE CIB NY                      | CREDIT AGRICOLE CIB NY                                                               | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |      2000 | PA      | $2000.00      | 0.01%             |  |  |  | No            |                  2 | On Loan: No      |
| CORCEPT THERAPEUTICS INCORPORATED           | CORCEPT THERAPEUTICS INC                                                             | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |      5350 | NS      | $108658.50    | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Aclaris Therapeutics Inc                    | ACLARIS THERAPEUTICS INC                                                             | CUSIP: 00461U105<br>LEI: 5493000B2LQ9QTW1DF52 | Long             | EC               | CORP              | US        |      2867 | NS      | $45155.25     | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| JOHNSON & JOHNSON                           | JOHNSON JOHNSON                                                                      | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |     16942 | NS      | $2992804.30   | 22.14%            |  |  |  | No            |                  1 | On Loan: No      |
| VIATRIS INC.                                | VIATRIS INC                                                                          | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |     55039 | NS      | $612584.07    | 4.53%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2023-01-30

**Name of Applicant:** ProFunds

**Signature:** Denise Lewis

**Name of Signer:** Denise Lewis

**Title:** Treasurer and Principal Financial Officer