# EDGAR Filing Document

**Accession Number:** 0002026172
**File Stem:** 0001892688-25-000149
**Filing Date:** 2025-8
**Character Count:** 13622
**Document Hash:** 8ddf6e8444f4114dab76092608249376
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001892688-25-000149.hdr.sgml**: 20250814

**ACCESSION NUMBER**: 0001892688-25-000149

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250814

**DATE AS OF CHANGE**: 20250814

**EFFECTIVENESS DATE**: 20250814

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** DIADEMA PARTNERS LP
- **CENTRAL INDEX KEY:** 0002026172

**ORGANIZATION NAME:**
- **EIN:** 991928849
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-25172
- **FILM NUMBER:** 251215128

**BUSINESS ADDRESS:**
- **STREET 1:** 2140 HEADQUARTERS PLAZA
- **STREET 2:** EAST TOWER, 2ND FLOOR
- **CITY:** MORRISTOWN
- **STATE:** NJ
- **ZIP:** 07960
- **BUSINESS PHONE:** 917-513-8539

**MAIL ADDRESS:**
- **STREET 1:** 2140 HEADQUARTERS PLAZA
- **STREET 2:** EAST TOWER, 2ND FLOOR
- **CITY:** MORRISTOWN
- **STATE:** NJ
- **ZIP:** 07960

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 06-30-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** DIADEMA PARTNERS LP<br>**Address:** 2140 HEADQUARTERS PLAZA<br>EAST TOWER 2ND FLOOR<br>MORRISTOWN, NJ 07960

**Form 13F File Number:** 028-25172

**CRD Number (if applicable):** 000331527

**SEC File Number (if applicable):** 801-130477

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Zachary Canonico<br>**Title:** Chief Compliance Officer and Chief Operating Officer<br>**Phone:** 646-979-8432

**Signature, Place, and Date of Signing:**

Zachary Canonico  MORRISTOWN, NJ  08-14-2025<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 96

**Form 13F Information Table Value Total:** $328219079

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 89BIO INC | COM | 282559103 |  | 966111 | 98382 | SH |  | SOLE |  | 98382 | 0 | 0 |
| ACADIA PHARMACEUTICALS INC | COM | 004225108 |  | 1917573 | 88900 | SH | Call | SOLE |  | 88900 | 0 | 0 |
| ARS PHARMACEUTICALS INC | COM | 82835W108 |  | 4898215 | 280700 | SH | Call | SOLE |  | 280700 | 0 | 0 |
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 |  | 4061046 | 122100 | SH | Call | SOLE |  | 122100 | 0 | 0 |
| ALECTOR INC | COM | 014442107 |  | 372432 | 266023 | SH |  | SOLE |  | 266023 | 0 | 0 |
| ALTIMMUNE INC | COM NEW | 02155H200 |  | 4887423 | 1262900 | SH | Call | SOLE |  | 1262900 | 0 | 0 |
| ALTIMMUNE INC | COM NEW | 02155H200 |  | 663318 | 171400 | SH | Put | SOLE |  | 171400 | 0 | 0 |
| AMGEN INC | COM | 031162100 |  | 14546841 | 52100 | SH |  | SOLE |  | 52100 | 0 | 0 |
| AMGEN INC | COM | 031162100 |  | 17338941 | 62100 | SH | Put | SOLE |  | 62100 | 0 | 0 |
| AMICUS THERAPEUTICS INC | COM | 03152W109 |  | 752922 | 131400 | SH | Call | SOLE |  | 131400 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 459142 | 10572 | SH |  | SOLE |  | 10572 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 6788109 | 156300 | SH | Call | SOLE |  | 156300 | 0 | 0 |
| ARVINAS INC | COM | 04335A105 |  | 709909 | 96455 | SH |  | SOLE |  | 96455 | 0 | 0 |
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 |  | 10602449 | 192877 | SH |  | SOLE |  | 192877 | 0 | 0 |
| BIOHAVEN LTD | COM | G1110E107 |  | 1411000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| BIOMEA FUSION INC | COM | 09077A106 |  | 889020 | 493900 | SH | Call | SOLE |  | 493900 | 0 | 0 |
| BIOMEA FUSION INC | COM | 09077A106 |  | 135000 | 75000 | SH | Call | SOLE |  | 75000 | 0 | 0 |
| BRIDGEBIO PHARMA INC | COM | 10806X102 |  | 5673852 | 131400 | SH | Call | SOLE |  | 131400 | 0 | 0 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 |  | 5447680 | 112000 | SH | Call | SOLE |  | 112000 | 0 | 0 |
| CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 |  | 1058538 | 106600 | SH | Put | SOLE |  | 106600 | 0 | 0 |
| CARDIFF ONCOLOGY INC | COM | 14147L108 |  | 655515 | 208100 | SH | Call | SOLE |  | 208100 | 0 | 0 |
| CLIMB BIO INC | COM | 28658R106 |  | 870647 | 702135 | SH |  | SOLE |  | 702135 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 2816089 | 392213 | SH |  | SOLE |  | 392213 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 49542 | 6900 | SH | Call | SOLE |  | 6900 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 1446052 | 201400 | SH | Put | SOLE |  | 201400 | 0 | 0 |
| CORCEPT THERAPEUTICS INC | COM | 218352102 |  | 7354680 | 100200 | SH | Put | SOLE |  | 100200 | 0 | 0 |
| ELEDON PHARMACEUTICALS INC | COM | 28617K101 |  | 175101 | 64613 | SH |  | SOLE |  | 64613 | 0 | 0 |
| ELEVATION ONCOLOGY INC | COM | 28623U101 |  | 133233 | 362935 | SH |  | SOLE |  | 362935 | 0 | 0 |
| ELI LILLY  CO | COM | 532457108 |  | 11549516 | 14816 | SH |  | SOLE |  | 14816 | 0 | 0 |
| ELI LILLY  CO | COM | 532457108 |  | 16136271 | 20700 | SH | Put | SOLE |  | 20700 | 0 | 0 |
| ELI LILLY  CO | COM | 532457108 |  | 7795300 | 10000 | SH | Call | SOLE |  | 10000 | 0 | 0 |
| GILEAD SCIENCES INC | COM | 375558103 |  | 3326100 | 30000 | SH |  | SOLE |  | 30000 | 0 | 0 |
| GOSSAMER BIO INC | COM | 38341P102 |  | 1014504 | 824800 | SH | Call | SOLE |  | 824800 | 0 | 0 |
| IMMUNOCORE HLDGS PLC | ADS | 45258D105 |  | 3275570 | 104384 | SH |  | SOLE |  | 104384 | 0 | 0 |
| ITEOS THERAPEUTICS INC | COM | 46565G104 |  | 2055814 | 206200 | SH |  | SOLE |  | 206200 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 |  | 11086675 | 104473 | SH |  | SOLE |  | 104473 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 |  | 5306000 | 50000 | SH | Call | SOLE |  | 50000 | 0 | 0 |
| MANNKIND CORP | COM NEW | 56400P706 |  | 1944426 | 519900 | SH | Call | SOLE |  | 519900 | 0 | 0 |
| MERCK  CO INC | COM | 58933Y105 |  | 1583200 | 20000 | SH |  | SOLE |  | 20000 | 0 | 0 |
| MEREO BIOPHARMA GROUP PLC | SPON ADS | 589492107 |  | 106774 | 39400 | SH | Put | SOLE |  | 39400 | 0 | 0 |
| MEREO BIOPHARMA GROUP PLC | SPON ADS | 589492107 |  | 3570696 | 1317600 | SH | Call | SOLE |  | 1317600 | 0 | 0 |
| MIND MEDICINE MINDMED INC | COM NEW | 60255C885 |  | 1028899 | 158536 | SH |  | SOLE |  | 158536 | 0 | 0 |
| MODERNA INC | COM | 60770K107 |  | 2759000 | 100000 | SH | Put | SOLE |  | 100000 | 0 | 0 |
| MODERNA INC | COM | 60770K107 |  | 2816939 | 102100 | SH | Call | SOLE |  | 102100 | 0 | 0 |
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 |  | 1949360 | 41300 | SH | Put | SOLE |  | 41300 | 0 | 0 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 |  | 85871 | 47474 | SH | Call | SOLE |  | 47474 | 0 | 0 |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 |  | 11820139 | 94042 | SH |  | SOLE |  | 94042 | 0 | 0 |
| NOVO-NORDISK A S | ADR | 670100205 |  | 6902000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| NUVALENT INC | COM | 670703107 |  | 381500 | 5000 | SH |  | SOLE |  | 5000 | 0 | 0 |
| OCULAR THERAPEUTIX INC | COM | 67576A100 |  | 1268576 | 136700 | SH | Call | SOLE |  | 136700 | 0 | 0 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 |  | 1080579 | 253657 | SH |  | SOLE |  | 253657 | 0 | 0 |
| PACIRA BIOSCIENCES INC | COM | 695127100 |  | 1408331 | 58926 | SH |  | SOLE |  | 58926 | 0 | 0 |
| PFIZER INC | COM | 717081103 |  | 4848000 | 200000 | SH | Call | SOLE |  | 200000 | 0 | 0 |
| PHATHOM PHARMACEUTICALS INC | COM | 71722W107 |  | 386419 | 40294 | SH |  | SOLE |  | 40294 | 0 | 0 |
| PROQR THRAPEUTICS N V | SHS EURO | N71542109 |  | 321696 | 157694 | SH |  | SOLE |  | 157694 | 0 | 0 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 |  | 4210745 | 76185 | SH |  | SOLE |  | 76185 | 0 | 0 |
| PROTHENA CORP PLC | SHS | G72800108 |  | 607000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| PURETECH HEALTH PLC | ADS | 746237106 |  | 126339 | 7324 | SH |  | SOLE |  | 7324 | 0 | 0 |
| RECURSION PHARMACEUTICALS IN | CL A | 75629V104 |  | 3533904 | 698400 | SH | Call | SOLE |  | 698400 | 0 | 0 |
| REGENERON PHARMACEUTICALS | COM | 75886F107 |  | 2943675 | 5607 | SH |  | SOLE |  | 5607 | 0 | 0 |
| RELAY THERAPEUTICS INC | COM | 75943R102 |  | 150911 | 43616 | SH |  | SOLE |  | 43616 | 0 | 0 |
| REPLIMUNE GROUP INC | COM | 76029N106 |  | 301767 | 32483 | SH |  | SOLE |  | 32483 | 0 | 0 |
| REVIVA PHARMACEUTCLS HLDGS I | COM | 76152G100 |  | 1042483 | 2735457 | SH |  | SOLE |  | 2735457 | 0 | 0 |
| REVIVA PHARMACEUTCLS HLDGS I | COM | 76152G100 |  | 1524400 | 4000000 | SH | Call | SOLE |  | 4000000 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 |  | 2909316 | 79079 | SH |  | SOLE |  | 79079 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 |  | 7358000 | 200000 | SH | Call | SOLE |  | 200000 | 0 | 0 |
| SPDR SERIES TRUST | S BIOTECH | 78464A870 |  | 8293000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| SCHOLAR ROCK HLDG CORP | COM | 80706P103 |  | 2228839 | 62926 | SH |  | SOLE |  | 62926 | 0 | 0 |
| SELLAS LIFE SCIENCES GROUP I | COM NEW | 81642T209 |  | 876000 | 400000 | SH | Call | SOLE |  | 400000 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 |  | 23806255 | 284152 | SH |  | SOLE |  | 284152 | 0 | 0 |
| SUMMIT THERAPEUTICS INC | COM | 86627T108 |  | 19833 | 932 | SH |  | SOLE |  | 932 | 0 | 0 |
| SUMMIT THERAPEUTICS INC | COM | 86627T108 |  | 1589616 | 74700 | SH | Call | SOLE |  | 74700 | 0 | 0 |
| SUMMIT THERAPEUTICS INC | COM | 86627T108 |  | 1064000 | 50000 | SH | Put | SOLE |  | 50000 | 0 | 0 |
| TG THERAPEUTICS INC | COM | 88322Q108 |  | 13368414 | 371448 | SH |  | SOLE |  | 371448 | 0 | 0 |
| TANGO THERAPEUTICS INC | COM | 87583X109 |  | 1024000 | 200000 | SH | Call | SOLE |  | 200000 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 969248 | 259852 | SH |  | SOLE |  | 259852 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 600157 | 160900 | SH | Call | SOLE |  | 160900 | 0 | 0 |
| TREVI THERAPEUTICS INC | COM | 89532M101 |  | 1016490 | 185830 | SH |  | SOLE |  | 185830 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 1962895 | 53985 | SH |  | SOLE |  | 53985 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 4483188 | 123300 | SH | Put | SOLE |  | 123300 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 7890120 | 217000 | SH | Call | SOLE |  | 217000 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 |  | 1451154 | 104100 | SH | Call | SOLE |  | 104100 | 0 | 0 |
| UROGEN PHARMA LTD | COM | M96088105 |  | 2055000 | 150000 | SH |  | SOLE |  | 150000 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 6446245 | 198285 | SH |  | SOLE |  | 198285 | 0 | 0 |
| VERTEX PHARMACEUTICALS INC | COM | 92532F100 |  | 4452000 | 10000 | SH |  | SOLE |  | 10000 | 0 | 0 |
| VIKING THERAPEUTICS INC | COM | 92686J106 |  | 5232902 | 197468 | SH |  | SOLE |  | 197468 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 |  | 1706413 | 122061 | SH |  | SOLE |  | 122061 | 0 | 0 |
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 |  | 807844 | 403922 | SH |  | SOLE |  | 403922 | 0 | 0 |
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 |  | 400 | 200 | SH | Call | SOLE |  | 200 | 0 | 0 |
| ZAI LAB LTD | ADR | 98887Q104 |  | 13236 | 3785 | SH |  | SOLE |  | 3785 | 0 | 0 |
| ZYMEWORKS INC | COM | 98985Y108 |  | 2250215 | 179300 | SH | Call | SOLE |  | 179300 | 0 | 0 |
| ATYR PHARMA INC | COM NEW | 002120202 |  | 386334 | 76200 | SH | Put | SOLE |  | 76200 | 0 | 0 |
| ATYR PHARMA INC | COM NEW | 002120202 |  | 652509 | 128700 | SH | Call | SOLE |  | 128700 | 0 | 0 |
| ARGENX SE | SPONSORED ADR | 04016X101 |  | 3292988 | 5974 | SH |  | SOLE |  | 5974 | 0 | 0 |
| SCPHARMACEUTICALS INC | COM | 810648105 |  | 829144 | 217623 | SH |  | SOLE |  | 217623 | 0 | 0 |
| SCPHARMACEUTICALS INC | COM | 810648105 |  | 1853565 | 486500 | SH | Call | SOLE |  | 486500 | 0 | 0 |

---