# EDGAR Filing Document

**Accession Number:** 0001174940
**File Stem:** 0001641172-25-013324
**Filing Date:** 2025-6
**Character Count:** 1826
**Document Hash:** 9604438a3e2761fbfc477a99242c0624
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001641172-25-013324.hdr.sgml**: 20250902

**ACCESSION NUMBER**: 0001641172-25-013324

**CONFORMED SUBMISSION TYPE**: DRSLTR

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250602

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ORAGENICS INC
- **CENTRAL INDEX KEY:** 0001174940
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 593410522
- **STATE OF INCORPORATION:** FL
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DRSLTR

**BUSINESS ADDRESS:**
- **STREET 1:** 1990 MAIN STREET
- **STREET 2:** SUITE 750
- **CITY:** SARASOTA
- **STATE:** FL
- **ZIP:** 34236
- **BUSINESS PHONE:** 8132867900

**MAIL ADDRESS:**
- **STREET 1:** 1990 MAIN STREET
- **STREET 2:** SUITE 750
- **CITY:** SARASOTA
- **STATE:** FL
- **ZIP:** 34236

June 2, 2025

**VIA EDGAR**

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street NE

Washington, D.C. 20549

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| | |
|:---|:---|
| **Re:** | **Oragenics, Inc.** |
|  | **Draft Registration Statement on Form S-1** |
|  | **File No. 333-** |
|  | **Filed June 2, 2025** |

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Ladies and Gentlemen:

The Company affirms that the above-referenced Registration Statement on Form S-1 (the "Registration Statement") confidentially submitted on June 2, 2025 and the subsequent public filing of the Registration Statement shall be publicly available on the EDGAR system at least two business days prior to any requested effective time and date.

If you have any questions regarding this filing, please do not hesitate to contact our counsel Mark Catchur at (813) 227-2264 or Julio Esquivel at (813) 227-2325.

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| |
|:---|
| Very truly yours, |
| */s/ Janet Huffman* |
| Janet Huffman<br> Chief Executive Officer |

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