# EDGAR Filing Document

**Accession Number:** 0001128189
**File Stem:** 0001079973-25-001708
**Filing Date:** 2025-11
**Character Count:** 73134
**Document Hash:** b818a2fd6c73842a3a06ebaec675a598
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001079973-25-001708.hdr.sgml**: 20251113

**ACCESSION NUMBER**: 0001079973-25-001708

**CONFORMED SUBMISSION TYPE**: 10-Q

**PUBLIC DOCUMENT COUNT**: 53

**CONFORMED PERIOD OF REPORT**: 20250930

**FILED AS OF DATE**: 20251113

**DATE AS OF CHANGE**: 20251113

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ProtoKinetix, Inc.
- **CENTRAL INDEX KEY:** 0001128189
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 943355026
- **STATE OF INCORPORATION:** NV
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 10-Q
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-32917
- **FILM NUMBER:** 251478407

**BUSINESS ADDRESS:**
- **STREET 1:** 109 W. MAIN ST.
- **CITY:** DALTON
- **STATE:** OH
- **ZIP:** 44618
- **BUSINESS PHONE:** 330-445-4971

**MAIL ADDRESS:**
- **STREET 1:** 109 W. MAIN ST.
- **CITY:** DALTON
- **STATE:** OH
- **ZIP:** 44618

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** RJV NETWORK INC
- **DATE OF NAME CHANGE:** 20010130

?xml version='1.0' encoding='ASCII'?

**UNITED STATES SECURITIES AND EXCHANGE COMMISSION**

**Washington, D. C. 20549**

**FORM 10-Q**

**☒** **QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934**

For the quarterly period ended September 30, 2025

OR

**☐** **TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934**

For the transition period from _____________ to ___________________.

Commission File Number: **000-32917**

---

| |
|:---|
| <br> **PROTOKINETIX, INCORPORATED** |
| (Exact name of registrant as specified in its charter) |

---

---

| | |
|:---|:---|
| **Nevada** | **94-3355026** |
| (State or other jurisdiction of incorporation or organization) | (I.R.S. Employer Identification No.) |

---

---

| |
|:---|
| **109 W Main St.**<br> **Dalton, Ohio 44618** |
| (Address of principal executive offices, including zip code) |

---

(Registrant's telephone number, including area code**: 740-434-5041**)

Securities registered pursuant to Section 12(b) of the Act:

<u>Title of each class</u> <u>Trading Symbol</u> <u>Name of each exchange on which registered</u> <br> N/A

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. ☒ Yes☐ No

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). ☒ Yes☐ No

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

Large accelerated filer ☐ Accelerated filer ☐ <br> Non-accelerated filer☐ Smaller reporting company ☒ <br> Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes ☐ No ☒

As of November 13, 2025 there were 391,580,152 shares of ProtoKinetix, Incorporated common stock that were issued and outstanding.

**PROTOKINETIX, INCORPORATED**

**TABLE OF CONTENTS**

---

| | |
|:---|:---|
| **PART I** |  |
| &nbsp;&nbsp;&nbsp;**FINANCIAL INFORMATION** |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 1. Financial Statements | 2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Unaudited Balance Sheets | 2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Unaudited Statements of Operations | 3 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Unaudited Statement of Stockholders' Equity | 4 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Unaudited Statements of Cash Flows | 5 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Notes to Unaudited Financial Statements | 6 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations | 14 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 3. Quantitative and Qualitative Disclosures About Market Risk | 17 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 4. Controls and Procedures | 17 |
| **PART II** |  |
| &nbsp;&nbsp;&nbsp;**OTHER INFORMATION** |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 1. Legal Proceedings | 18 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 1A. Risk Factors | 18 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 2. Unregistered Sales of Equity Securities and Use of Proceeds | 18 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 3. Defaults Upon Senior Securities | 18 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 4. Mine Safety Disclosure | 18 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 5. Other Information | 18 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Item 6. Exhibits | 19 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Signatures | 20 |

---

**ITEM 1 - FINANCIAL STATEMENTS**

**PROTOKINETIX, INCORPORATED**

(A Development Stage Company)

**BALANCE SHEETS**

(Unaudited)

---

| | | |
|:---|:---|:---|
|  | **September 30, 2025** | **December 31, 2024** |
| **ASSETS** |  |  |
| Current Assets |  |  |
| Cash | $607 | $(4697) |
| Prepaid expenses (Note 3) | 1050 | 1050 |
| Total current assets | 1657 | (3647) |
| Intangible assets (Note 4) | 475966 | 469784 |
| Total assets | $477623 | $466137 |
| **LIABILITIES AND STOCKHOLDERS' EQUITY** |  |  |
| Current Liabilities |  |  |
| Accounts payable and accrued liabilities | $227196 | $124047 |
| Total liabilities | 227196 | 124047 |
| Stockholders' Equity |  |  |
| Common stock, $0.0000053 par value; 500,000,000 common shares authorized; 390,080,152 and 371,880,152 shares issued and outstanding as at September 30, 2025 and December 31, 2024 respectively (Note 7) | 2083 | 1987 |
| Additional paid-in capital | 48750153 | 48568249 |
| Accumulated deficit | (48501809) | (48228146) |
| Total stockholders' equity | 250427 | 342090 |
| Total liabilities and stockholders' equity | $477623 | $466137 |

---

**Basis of Presentation – Going Concern Uncertainties** (Note 1)

**Commitments and Contingency** (Note 9)

See Notes to Financial Statements

**PROTOKINETIX, INCORPORATED**

(A Development Stage Company)

**STATEMENTS OF OPERATIONS**

(Unaudited)

For the Three and Nine Months Ended September 30, 2025 and 2024

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three months ended <br> September 30, 2025** | **Three months ended <br> September 30, 2024** | **Nine months ended <br> September 30, 2025** | **Nine months ended <br> September 30, 2024** |
| **EXPENSES** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization – intangible assets (Note 4) | $12641 | $15120 | $38189 | $39461 |
| &nbsp;&nbsp;&nbsp;&nbsp;General and administrative | 16238 | 16254 | 45090 | 43589 |
| &nbsp;&nbsp;&nbsp;&nbsp;Professional fees | 31842 | 30845 | 107991 | 98647 |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development | 24185 | 21000 | 82392 | 78625 |
| &nbsp;&nbsp;&nbsp;&nbsp;Share-based compensation (Note 5) |  | 1354 |  | 1354 |
| **Total operating expenses** | (84906) | (84573) | (273662) | (261676) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net loss for the period | $(84906) | $(84573) | $(273662) | $(261676) |
| Net loss per common share (basic and diluted) | $(0.00) | $(0.00) | $(0.00) | $(0.00) |
| Weighted average number of common shares outstanding (basic and diluted) | 389449717 | 364849717 | 384029419 | 355171271 |

---

See Notes to Financial Statements

**PROTOKINETIX, INCORPORATED**

**STATEMENT OF STOCKHOLDERS' EQUITY**

(Unaudited)

For the Nine Months Ended September 30, 2025

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Common Stock** | **Common Stock** | | | |
|  | **Shares** | **Amount** | **Additional <br> Paid-in**<br>**capital** | **Accumulated**<br>**deficit** |<br>**Total** |
| **Balance, December 31, 2024** | 371880152 | $1987 | $48568249 | $(48228146) | $342090 |
| Issuance of common stock pursuant to private placement offering | 17750000 | 94 | 177406 |  | 177500 |
| Issuance of common stock in exchange for consulting services | 450000 | 2 | 4498 |  | 4500 |
| Net loss for the period |  |  |  | (273663) | (273663) |
| **Balance, September 30, 2025** | 390080152 | $2083 | $48750153 | $(48501809) | $250427 |

---

For the Three Months Ended June 30, 2025

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Common Stock** | **Common Stock** | | | |
|  | **Shares** | **Amount** | **Additional <br> Paid-in**<br>**capital** | **Accumulated**<br>**deficit** |<br>**Total** |
| **Balance, June 30, 2025** | 389080152 | $2078 | $48740158 | $(48416903) | $325333 |
| Issuance of common stock pursuant to private placement offering | 1000000 | 5 | 9995 |  | 10000 |
| Net loss for the period |  |  |  | (84906) | (84906) |
| **Balance, September 30, 2025** | 390080152 | $2083 | $48750153 | $(48501809) | $250427 |

---

For the Nine Months Ended September 30, 2024

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Common Stock** | **Common Stock** | | | |
|  | **Shares** | **Amount** | **Additional <br> Paid-in**<br>**capital** | **Accumulated**<br>**deficit** |<br>**Total** |
| **Balance, December 31, 2023** | 346213485 | $1850 | $48297969 | $(47863958) | $435861 |
| Issuance of common stock pursuant to private placement offering | 20766667 | 111 | 215889 |  | 216000 |
| Fair-value of share based compensation |  |  | 1354 |  | 1354 |
| Net loss for the period |  |  |  | (261676) | (261676) |
| **Balance, September 30, 2024** | 366980152 | $1961 | $48515212 | $(48125634) | $391539 |

---

For the Three Months Ended September 30, 2024

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Common Stock** | **Common Stock** | | | |
|  | **Shares** | **Amount** | **Additional <br> Paid-in**<br>**capital** | **Accumulated**<br>**deficit** |<br>**Total** |
| **Balance, June 30, 2024** | 360980152 | $1930 | $48453889 | $(48041061) | $414758 |
| Issuance of common stock pursuant to private placement offering | 6000000 | 31 | 59969 |  | 60000 |
| Fair-value of share based compensation |  |  | 1354 |  | 1354 |
| Net loss for the period |  |  |  | (84573) | (84573) |
| **Balance, September 30 , 2024** | 366980152 | $1961 | $48515212 | $(48125634) | $391539 |

---

See Notes to Financial Statements

**PROTOKINETIX, INCORPORATED**

(A Development Stage Company)

**STATEMENTS OF CASH FLOWS**

(Unaudited)

For the Nine Months Ended September 30, 2025 and 2024

---

| | | |
|:---|:---|:---|
|  | **Nine Months <br> ended<br> September 30, 2025** | **Nine Months <br> ended<br> September 30, 2024** |
| **CASH FLOWS USED IN OPERATING ACTIVITIES** |  |  |
| &nbsp;&nbsp;Net loss for the period | $(273663) | $(261676) |
| &nbsp;&nbsp;Adjustments to reconcile net loss to cash used in operating activities: |  |  |
| &nbsp;&nbsp;Amortization – intangible assets | 38189 | 39461 |
| &nbsp;&nbsp;Fair value of share-based compensation |  | 1354 |
| &nbsp;&nbsp;Changes in operating assets and liabilities: |  |  |
| &nbsp;&nbsp;Accounts payable and accrued liabilities | 99539 | 43053 |
| &nbsp;&nbsp;Net cash used in operating activities | (135935) | (177808) |
| **CASH FLOWS USED IN INVESTING ACTIVITIES** |  |  |
| &nbsp;&nbsp;Purchase of intangible assets | (36261) | (52910) |
| &nbsp;&nbsp;Net cash used in investing activities | (36261) | (52910) |
| **CASH FLOWS FROM FINANCING ACTIVITIES** |  |  |
| &nbsp;&nbsp;Issuance of common stock for cash | 177500 | 216000 |
| &nbsp;&nbsp;Net cash from financing activities | 177500 | 216000 |
| &nbsp;&nbsp;Net change in cash | 5304 | (14718) |
| Cash, beginning of period | (4697) | 20408 |
| Cash, end of period | $607 | $5690 |
| Cash paid for interest | $— | $— |
| Cash paid for income taxes | $— | $— |
| Supplementary information- non-cash transactions: |  |  |
| Shares issued to settle accounts payable | 4500 |  |
| Intangible asset costs remaining in accounts payable | 25544 |  |

---

See Notes to Financial Statements

**PROTOKINETIX, INCORPORATED**

**(A Development Stage Company)**

NOTES TO FINANCIAL STATEMENTS

September 30, 2025

**Note 1. Basis of Presentation – Going Concern Uncertainties**

ProtoKinetix, Incorporated (the "Company"), a development stage company, was incorporated under the laws of the State of Nevada on December 23, 1999. The Company is a medical research company whose mission is the advancement of human health care.

The Company is currently researching the benefits and feasibility of synthesized Antifreeze Glycoproteins ("AFGP") or anti-aging glycoproteins, trademarked AAGP. During the year ended December 31, 2015, the Company acquired certain patents and rights for cash consideration of $30,000 (25,000 Euros), as well as additional patent applications for cash consideration of $10,000 and 6,000,000 share purchase warrants with a fair value of $25,000 (Note 4).

The Company's financial statements are prepared consistent with accounting principles generally accepted in the United States applicable to a going concern.

The Company has not developed a commercially viable product, has not generated any significant revenue to date, and has incurred losses since inception, resulting in a net accumulated deficit at September 30, 2025. These factors raise substantial doubt about the Company's ability to continue as a going concern.

The Company needs additional working capital to continue its medical research or to be successful in any future business activities and continue to pay its liabilities. Therefore, continuation of the Company as a going concern is dependent upon obtaining the additional working capital necessary to accomplish its objective. Management is presently engaged in seeking additional working capital through equity financing or related party loans. In addition, any significant disruption of global financial markets, reducing our ability to access capital, could negatively affect our liquidity and ability to continue operations. The exact impact is and will remain unknown and largely dependent upon future developments, including but not limited to restrictions on the activities of our domestic and international suppliers and shipment of goods.

The accompanying financial statements do not include any adjustments to the recorded assets or liabilities that might be necessary should the Company fail in any of the above objectives and is unable to operate for the coming year.

**Note 2. Summary of Significant Accounting Policies**

**<u>Basis of Presentation</u>**

The accompanying unaudited financial statements have been prepared by the Company in conformity with accounting principles generally accepted in the United States of America ("US GAAP") applicable to interim financial information and with the rules and regulations of the United States Securities and Exchange Commission. Accordingly, certain information and footnote disclosures normally included in financial statements prepared in accordance with generally accepted accounting principles have been condensed, or omitted, pursuant to such rules and regulations. In the opinion of management, the unaudited interim financial statements include all adjustments necessary for the fair presentation of the results of the interim periods presented. All adjustments are of a normal recurring nature, except as otherwise noted below. These financial statements should be read in conjunction with the Company's audited financial statements and notes thereto for the year ended December 31, 2024, included in the Company's Annual Report on Form 10-K, filed March 28, 2025, with the Securities and Exchange Commission. The results of operations for the interim periods are not necessarily indicative of the results of operations for any other interim period or for a full fiscal year.

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 2. Summary of Significant Accounting Policies** (cont'd)

**<u>Use of Estimates</u>**

Preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and reported amounts of revenue and expenses during the reporting period. Actual results could differ from those estimates. The more significant accounting estimates inherent in the preparation of the Company's financial statements include estimates as to valuation of equity related instruments issued, deferred income taxes, and the useful life and impairment of intangible assets.

**<u>Cash</u>**

Cash consists of funds held in checking accounts. Cash balances may exceed federally insured limits from time to time.

**<u>Fair Value of Financial Instruments</u>**

Financial instruments, which includes cash, accounts payable and accrued liabilities are carried at amortized cost, which management believes approximates fair value due to the short-term nature of these instruments.

The Company measures the fair value of financial assets and liabilities pursuant to ASC 820 "Fair Value Measurements and Disclosures" which defines fair value, establishes a framework for measuring fair value, and expands disclosures about fair value measurements. ASC 820 establishes a fair value hierarchy, which requires an entity to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value. The policy describes three levels of inputs that may be used to measure fair value:

Level 1 – quoted prices in active markets for identical assets or liabilities.

Level 2 – quoted prices for similar assets and liabilities in active markets or inputs that are observable.

Level 3 – inputs that are unobservable (for example cash flow modeling inputs based on assumptions).

At September 30, 2025, there were no other assets or liabilities subject to additional disclosure.

**<u>Income Taxes</u>**

The Company accounts for income taxes following the assets and liability method in accordance with the ASC 740 "Income Taxes." Under such method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases. The Company applies the accounting guidance issued to address the accounting for uncertain tax positions. This guidance clarifies the accounting for income taxes, by prescribing a minimum recognition threshold a tax position is required to meet before being recognized in the financial statements as well as provides guidance on derecognition, measurement, classification, interest and penalties, accounting in interim periods, disclosure and transition. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years that the asset is expected to be recovered or the liability settled.

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 2. Summary of Significant Accounting Policies** (cont'd)

**<u>Intangible assets – patent and patent application costs</u>**

The Company owns intangible assets consisting of certain patents and patent applications. Intangible assets acquired separately are measured on initial recognition at cost. Following initial recognition, intangible assets are carried at cost less any accumulated amortization and any accumulated impairment losses. Subsequent expenditures are capitalized only when they increase the future economic benefits embodied in the specific asset to which they relate. All other expenditures are recognized in profit or loss as incurred.

As at September 30, 2025, the Company does not hold any intangible assets with indefinite lives.

Intangible assets with finite lives are amortized over the useful economic life and assessed for impairment whenever there is an indication that the intangible asset may be impaired. The amortization method and amortization period of an intangible asset with a finite life is reviewed at least annually.

Changes in the expected useful life or the expected pattern of consumption of future economic benefits embodied in the asset is accounted for by changing the amortization period or method, as appropriate, and are treated as changes in accounting estimates.

Amortization is recognized in profit or loss on a straight-line basis over the estimated useful lives of the Company's patents, whereas no amortization has been recognized on the not yet approved patent application costs at September 30, 2025.

**<u>Research and Development Costs</u>**

Research and development costs are expensed as incurred. This includes all research consultant's fees and costs of contract research organizations.

**<u>Loss per Share and Potentially Dilutive Securities</u>**

Basic loss per share is computed by dividing the net loss available to common stockholders by the weighted average number of common shares outstanding in the period. Diluted loss per share takes into consideration common shares outstanding (computed under basic earnings per share) and potentially dilutive securities. The effect of 94,790,000 stock options (September 30, 2024 – 94,790,000), and 23,700,000 warrants (September 30, 2024 – 6,000,000) were not included in the computation of diluted loss per share for all periods presented because it was anti-dilutive due to the Company's losses.

**<u>Share-Based Compensation</u>**

The Company has granted warrants and options to purchase shares of the Company's common stock to various parties for consulting services. The fair values of the warrants and options issued have been estimated using the Black-Scholes Option Pricing Model.

The Company accounts for stock compensation with persons classified as employees for accounting purposes in accordance with ASC 718 "Compensation – Stock Compensation", which recognizes awards at fair value on the date of grant and recognition of compensation over the service period for awards expected to vest. Cliff Vesting is used and awards vest on the last day of the vesting period. The fair value of stock options is determined using the Black-Scholes Option Pricing Model. The fair value of common shares issued for services is determined based on the Company's stock price on the date of issuance.

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 2. Summary of Significant Accounting Policies** (cont'd)

**<u>Share-Based Compensation</u>** (cont'd)

Share-based compensation for non-employees in exchange for goods and services used or consumed in an entity's own operations are also recorded at fair value on the measurement date and accounted for in accordance with ASC 718. The measurement of share-based compensation is subject to periodic adjustment as the underlying instruments vest. The fair value of stock options is estimated using the Black-Scholes Option Pricing Model and the compensation charges are amortized over the vesting period.

**<u>Common stock</u>**

Common stock issued for non-monetary consideration are recorded at their fair value on the measurement date and classified as equity. The measurement date is defined as the earliest of the date at which the commitment for performance by the counterparty to earn the common shares is reached or the date at which the counterparty's performance is complete.

Transaction costs directly attributable to the issuance of common stock, units and stock options are recognized as a deduction from equity, net of any tax effects.

**<u>Related Party Transactions</u>**

A related party is generally defined as (i) any person that holds 10% or more of the Company's securities and their immediate families, (ii) the Company's management, (iii) someone that directly or indirectly controls, is controlled by or is under common control with the Company, or (iv) anyone who can significantly influence the financial and operating decisions of the Company. A transaction is considered to be a related party transaction when there is a transfer of resources or obligations between related parties.

**<u>Recent Accounting Pronouncements</u>**

Certain new accounting pronouncements that have been issued are not expected to have a material effect on the Company's financial statements.

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 3. Prepaid Expenses** 

The following summarizes the Company's prepaid expenses outstanding as at September 30, 2025 and December 31, 2024:

---

| | | |
|:---|:---|:---|
|  | **September 30, <br> 2025** | **December 31, <br> 2024** |
| Rental deposit | $1050 | $1050 |

---

**Note 4. Intangible Assets**

Intangible asset transactions are summarized as follows:

---

| | | | |
|:---|:---|:---|:---|
| Intangible asset transactions | **Patent Rights** | **Patent Application <br> Rights** | **Total** |
| **Cost** |  |  |  |
| Balance, December 31, 2023 | $30000 | $555308 | $585308 |
| Additions |  | 63555 | 63555 |
| Balance, December 31, 2024 | $30000 | $618863 | $648863 |
| Additions |  | 44371 | 44371 |
| Balance, September 30, 2025 | $30000 | $663234 | $693234 |
| **Accumulated amortization** |  |  |  |
| Balance, December 31, 2023 | $25500 | $100709 | $126209 |
| Amortization | 3000 | 49870 | 52870 |
| Balance, December 31, 2024 | $28500 | $150579 | $179079 |
| Amortization | 1500 | 36689 | 38189 |
| Balance, September 30, 2025 | $30000 | $187268 | $217268 |
| **Net carrying amounts** |  |  |  |
| December 31, 2024 | $1500 | $468284 | $469784 |
| September 30, 2025 | $— | $475966 | $475966 |

---

During the year ended December 31, 2015, the Company entered into an Assignment of Patents and Patent Application (effective January 1, 2015) (the "Patent Assignment") with the Institut National des Sciences Appliquees de Rouen ("INSA") for the assignment of certain patents and all rights associated therewith (the "Patents"). The Company and INSA had previously entered into a licensing agreement for the Patents in August 2004. The Patent Assignment transfers all of the Patents and rights associated therewith to the Company upon payment to INSA in the sum of $30,000 (25,000 Euros) (paid). During the nine month period ended September 30, 2025, the Company recorded $38,189 (2024 - $39,461) in amortization expense associated with the Patents Rights.

During the year ended December 31, 2015, the Company entered into a Technology Transfer Agreement with Grant Young for the assignment of his 50% ownership of certain patents and all rights associated therewith (the "Patent Application Rights"). In exchange for the Patent Application Rights, the Company agreed to pay $10,000 (paid) and to issue 6,000,000 warrants (issued) to purchase shares of the Company's common stock at an exercise price of $0.10 per share for a period of five years. The Patent Application Rights had a total fair value of $35,000, which was allocated as $10,000 to the cash consideration paid, with the remaining $25,000 being allocated to the warrant component of the overall consideration. The Company incurred an additional $663,234 in direct costs relating to the Patent Application Rights, $44,371 of which were incurred during nine month period ended September 30, 2025.

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 4. Intangible Assets** (cont'd)

The remaining 50% ownership of the Patent Application Rights was acquired from the Governors of the University of Alberta in exchange for a future gross revenue royalty from any product developed as a result of research done at the University.

During the year ended December 31, 2016, the Company entered into a Universal Assignment with Grant Young for the assignment of his ownership of certain new and useful improvements in an invention entitled "Use of Anti-Aging Glycoprotein for Enhancing Survival of Neurosensory Precursor Cells" (the "New Patent Application Rights"). In exchange for the New Patent Application Rights, the Company agreed to pay $1 (paid). The Company incurred $2,415 in direct costs relating to the New Patent Application Rights during the year ended December 31, 2016.

The Company amortizes patents and licenses that have been filed over their useful lives which range between 18.5 to 20 years. The costs of provisional patents and pending applications is not amortized until the patent is filed and is reviewed each reporting period. No amortization was recorded on the Patent Application Rights or the New Patent Application Rights to September 30, 2025.

**Note 5. Stock Options**

Pursuant to an amendment on March 15, 2022, the aggregate number of shares that may be issued under the 2017 Stock Option and Stock Bonus Plan (the "2017 Plan") is 97,700,000 shares, subject to adjustment as provided therein. The 2017 Plan is administered by the Company's Board of Directors, or a committee appointed by the Board of Directors, and includes two types of options. Options intended to qualify as incentive stock options under Section 422 of the Internal Revenue Code of 1986, as amended, are referred to as incentive options. Options that are not intended to qualify as incentive options are referred to as non-qualified options. The exercise price of an option may be paid in cash, in shares of the Company's common stock or other property having a fair market value equal to the exercise price of the option, or in a combination of cash, shares, other securities and property.

As of September 30, 2025, there are 94,790,000 options granted and outstanding under the 2017 Plan.

Total share-based compensation for stock options granted during the nine-month period September 30, 2025 was $Nil (2024 - $1,354).

Stock option transactions are summarized as follows:

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Number of <br> Stock Options** | **Weighted Average Exercise Price** | **Weighted Average Remaining Life** | **Weighted Average Remaining Life** |
|  |  |  | $— | **(Years)** |
| Outstanding, December 31, 2024, and September 30, 2025 | 94790000 |  |  | 3.43 |

---

The following non-qualified stock options were outstanding and exercisable at September 30, 2025:

---

| | | |
|:---|:---|:---|
| **Expiry date** | **Exercise Price** | **Number of <br> Options <br> Exercisable** |
|  | **$** | $ |
| October 26, 2026 |  | 500000 |
| November 26, 2026 |  | 250000 |
| December 6, 2028 |  | 93540000 |
| August 6, 2030 |  | 500000 |
|  |  | 94790000 |

---

As at September 30, 2025, the aggregate intrinsic value of the Company's stock options is $Nil (September 30, 2024 – $Nil). The weighted average fair value of stock options granted during the nine-month period ended September 30, 2025 is $Nil (2024 - $0.01).

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 6. Warrants**

Warrant transactions for the nine-months September 30, 2025 are summarized as follows:

---

| | | |
|:---|:---|:---|
|  | **Number of <br> Warrants** | **Weighted Average Exercise Price** |
|  | | $ |
| Outstanding, December 31, 2024 | 6000000 | 0.028 |
| &nbsp;&nbsp;&nbsp;&nbsp;Warrants granted | 17700000 | 0.01 |
| Outstanding at September 30, 2025 | 23700000 | 0.015 |

---

The following warrants were outstanding and exercisable as at September 30, 2025:

---

| | | |
|:---|:---|:---|
| **Number of Warrants** | **Exercise Price** | **Expiry Date** |
| 6000000 | 0.028 | December 12, 2028 |
| 500,000\* | 0.01 | February 17, 2026 |
| 1,500,000\* | 0.01 | February 20, 2026 |
| 500,000\* | 0.01 | February 21, 2026 |
| 2,000,000\* | 0.01 | February 28, 2026 |
| 750,000\* | 0.01 | March 15, 2026 |
| 450,000\* | 0.01 | March 15, 2026 |
| 7,500,000\* | 0.01 | March 27, 2026 |
| 1,000,000\* | 0.01 | April 2, 2026 |
| 2,000,000\* | 0.01 | April 8, 2026 |
| 500,000\* | 0.01 | April 11, 2026 |
| 500,000\* | 0.01 | June 26, 2026 |
| 500,000\* | 0.01 | July 25, 2026 |
| 23700000 |  | Total |

---

\* Each warrant exercises into ½ share of common stock.

**Note 7. Stockholders' Equity**

The Company is authorized to issue 500,000,000 (September 30, 2024 – 500,000,000) shares of $0.0000053 par value common stock. Each holder of common stock has the right to one vote but does not have cumulative voting rights. Shares of common stock are not subject to any redemption or sinking fund provisions, nor do they have any preemptive, subscription or conversion rights. Holders of common stock are entitled to receive dividends whenever funds are legally available and when declared by the board of directors, subject to the prior rights of holders of all classes of stock outstanding having priority rights as to dividends. No dividends have been declared or paid as of September 30, 2025 (September 30, 2024 - $Nil).

During the nine-month period ended September 30, 2025, the Company:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a) Issued 17,700,000 units (each unit consisting of 1 share of common stock and 1 warrant to purchase 1/2 share of common stock at $0.01) as part of a private placement for total cash proceeds of $172,500 and $4,500 of services.

b) Issued 500,000 shares of common stock (1,000,000 shares issued at $0.01) as part of a private placement for total proceeds of $5,000 .

During the nine-month period ended September 30, 2024, the Company:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a) Issued 1,666,667 shares of common stock (1,666,667 shares issued at $0.015) as part of a private placements for total proceeds of $25,000 .

b) Issued 19,100,000 shares of common stock (19,100,000 shares issued at $0.01) as part of a private placement for total proceeds of $191,000 .

**PROTOKINETIX, INCORPORATED**<br>**(A Development Stage Company)**<br>NOTES TO FINANCIAL STATEMENTS<br>September 30, 2025<br>

**Note 8. Related Party Transactions and Balances**

During the nine-month periods ended September 30, 2025 and 2024, the Company entered into the following related party transactions:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a) Pursuant to a consulting agreement with an effective date of November 14, 2017, a total of $45,000 (September 30, 2024 - $45,000) was paid or accrued to the Company's CFO. During the nine months ended September 30, 2025, the Company reimbursed a company controlled by the CFO a total of $4,500 (September 30, 2024 - $4,500) in office rent.

As at September 30, 2025, there were $105,700 balances owing to related parties (September 30, 2024 - $21,500).

**Note 9. Commitments and Contingency**

As at September 30, 2025, the Company has the following commitments:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a) Entered into a consulting agreement with an effective date of January 1, 2017 whereby the Company would pay the consultant $7,000 per month for providing research and development services.

b) Entered into a consulting agreement effective April 1, 2019, whereby the Company would pay the consultant $1,500 per month minimum plus travel expenses for a term of 1 year for providing research consulting services. Agreement renews annually unless otherwise terminated by either party with at least 30 days' notice.

**Note 10. Subsequent Events**

Subsequent to the quarter ended September 30, 2025, the Company:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a) Issued 1,500,000 shares of common stock at $0.01 to one of its consultants as payment for services rendered in the amount of $1,500 .

**Item 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS**

*Unless the context requires otherwise, references in this document to "ProtoKinetix", "we", "our", "us" or the "Company" are to ProtoKinetix, Incorporated.*

The following discussion provides information regarding the results of operations for the nine-month period ended September 30, 2025 and 2024, and our financial condition, liquidity and capital resources as of September 30, 2025 and December 31, 2024. The financial statements and the notes thereto contain detailed information that should be referred to in conjunction with this discussion.

***<u>Cautionary Note Regarding Forward-Looking Statements</u>***

The information discussed in this Quarterly Report on Form 10-Q include "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 (the "Securities Act") and Section 21E of the Securities Exchange Act of 1934 (the "Exchange Act"). All statements, other than statements of historical facts, included herein and therein concerning, among other things, planned capital expenditures, future cash flows and borrowings, pursuit of potential acquisition opportunities, our financial position, business strategy and other plans and objectives for future operations, are forward-looking statements. These forward-looking statements are identified by their use of terms and phrases such as "may," "expect," "estimate," "project," "plan," "believe," "intend," "achievable," "anticipate," "will," "continue," "potential," "should," "could," and similar terms and phrases. Although we believe that the expectations reflected in these forward-looking statements are reasonable, they do involve certain assumptions, risks and uncertainties and are not (and should not considered to be) guarantees of future performance. Our results could differ materially from those anticipated in these forward-looking statements as a result of certain factors, including, among others:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our capital requirements and the uncertainty of being able to obtain additional funding on terms acceptable to us;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our plans to develop and commercialize products from the AAGP® molecule;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Ongoing testing of the AAGP® molecule;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our intellectual property position;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our commercialization, marketing and manufacturing capabilities and strategy;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our ability to retain key members of our senior management and key scientific consultants;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The effects of competition;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our potential tax liabilities resulting from conducting business in the United States and Canada;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The effect of further sales or issuances of our common stock and the price and volume volatility of our common stock; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our common stock's limited trading history.

Finally, our future results will depend upon various other risks and uncertainties, including, but not limited to, those detailed in our filings with the SEC under the Exchange Act and the Securities Act, including our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and our Quarterly Report on Form 10-Q for the period ended September 30, 2025. All forward-looking statements attributable to us or persons acting on our behalf are expressly qualified in their entirety by the cautionary statements in this paragraph and elsewhere in this Quarterly Report. Other than as required under securities laws, we do not assume a duty to update these forward-looking statements, whether as a result of new information, subsequent events or circumstances, changes in expectations or otherwise

**Business Overview**

ProtoKinetix, Incorporated is a research and development stage bio-technology company focused on scientific medical research of AFGPs (Anti-Freeze Glycoproteins) or anti-aging glycoproteins, trademarked as AAGP®. The Company has recently been in the process of directing major efforts to the practical side of commercial validation. The commercial applications for AAGP® in large markets such as targeted health care solutions are numerous, and ProtoKinetix is currently working with researchers, business leaders and advisors and commercial entities to bring AAGP® to market.

**Results of Operations**

The following table shows selected financial data and operating results for the periods noted. Following the table, please see management's discussion of significant changes.

---

| | | |
|:---|:---|:---|
|  | **For the Nine Months Ended<br> September 30,** | **For the Nine Months Ended<br> September 30,** |
|  | **2025** | **2024** |
| **EXPENSES** |  |  |
| Amortization | $38189 | $39461 |
| General and Administrative | 45090 | 43589 |
| Professional Fees | 107991 | 98647 |
| Research and Development | 82393 | 78625 |
| Share-Based Compensation |  | 1354 |
| **Net loss for the period** | $(273663) | (261676) |

---

*Gross Profit and Expenses*

The Company's net loss was $273,663 for the nine-month period ended September 30, 2025 compared to $261,676 for the nine-month period ended September 30, 2024. The expenses were primarily incurred for professional fees, consulting services related to the operations of the Company's business, research and development and other general and administrative expenses. Significant changes from the prior nine-month period ended September 30, 2025 include:

General and administrative fees remained almost flat with a small increase of $1,501 from $43,589 to $45,090. There are no current year marketing projects planned that will significantly increase related expenses. Increase due to higher office expenses.

Professional fees increased by $9,344 from $98,647 to $107,991 due to increases in auditing fees and legal billing associated with year- end and interim reporting.

Research and development expenditures increased year over year with a change of $3,768 from $78,625 to $82,393 as the Company paid for molecule storage and consulting fees but has no current research projects underway. The company continues to pursue research partners for cost sharing and engages in institutes with grants available for continued studies on our patented AAGP molecule.

Share-based compensation was $Nil for current year compared to $1,354 for the nine months ended September 2024.

**Liquidity and Capital Resources**

The following summarizes our balance sheet at September 30, 2025 and December 31, 2024:

---

| | | |
|:---|:---|:---|
|  | **September 30, 2025** | **December 31, 2024** |
| Cash | $607 | $(4697) |
| Working Capital | $(213539) | $(127694) |

---

At September 30, 2025, we had $607 in cash and $1,657 in total current assets and a negative working capital equity position of $(225,539). Based upon our working capital equity as of September 30, 2025, we will require additional equity and/or debt financing in order to meet cash flow projections and carry forward our business objectives.

There can be no assurance that in the future we will be able to raise capital from outside sources in sufficient amounts to fund our new business. The failure to secure adequate outside funding would have an adverse effect on our plan of operation and results therefrom and a corresponding negative impact on stockholder liquidity.

  ****

***Sources and Uses of Cash***

*Net Cash Used in Operating Activities*

Net cash used in operating activities fell by $41,873 from $177,808 to $135,935 for the nine-months ended September 30, 2024, and 2025, respectively. With the year over year change primarily from a change in accounts payable.

*Net Cash Used in Investing Activities*

Net cash used for investing activities was $36,261 for the nine-month period ended September 30, 2025 while the Company had net cash used for investing activities of $52,910 for the comparative period. The difference is attributable to a year-to-date fluctuation in patent application billings for current year.

*Net Cash Provided by Financing Activities*

Net cash provided by financing activities fell $38,500 from $216,000 to $177,500 for the nine-months ended September 30, 2024, and 2025, respectively. The decrease of funding from private placements through the third quarter of 2025 reflects investor support for our slowing of operations and focus on finding financial partners for further research and development.

**Going Concern**

The accompanying financial statements have been prepared in conformity with accounting principles generally accepted in the United States ("U.S. GAAP"), which contemplate continuation of the Company as a going concern. The history of losses and the inability for the Company to make a profit from selling a good or service has raised substantial doubt about our ability to continue as a going concern. In spite of the fact that the current cash obligations of the Company are relatively minimal, given the cash position of the Company, we have very little cash to operate. We intend to fund the Company and attempt to meet corporate obligations by selling common stock. However, the price and volume of the Company's common stock is volatile.

**Off-Balance Sheet Arrangements**

None.

**Contractual Obligations**

As a smaller reporting company, we are not required to provide the information required by paragraph (a)(5) of this Item.

**Critical Accounting Policies**

The preparation of financial statements in conformity with U.S. GAAP requires management to make a variety of estimates and assumptions that affect (i) the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities as of the date of the financial statements, and (ii) the reported amounts of revenues and expenses during the reporting periods covered by the financial statements.

Our management routinely makes judgments and estimates about the effect of matters that are inherently uncertain. As the number of variables and assumptions affecting the future resolution of the uncertainties increase, these judgments become even more subjective and complex. Although we believe that our estimates and assumptions are reasonable, actual results may differ significantly from these estimates. Changes in estimates and assumptions based upon actual results may have a material impact on our results of operation and/or financial condition. Our significant accounting policies are disclosed in Note 2 to the Financial Statements included in this Form 10-Q.

While all of the significant accounting policies are important to the Company's financial statements, the following accounting policies and the estimates derived there from have been identified as being critical.

**Share-Based Compensation**

The Company has granted warrants and options to purchase shares of the Company's common stock to various parties for consulting services. The fair values of the warrants and options issued have been estimated using the Black-Scholes Option Pricing Model.

The Company accounts for stock compensation with persons classified as employees for accounting purposes in accordance with ASC 718 "Compensation – Stock Compensation", which recognizes awards at fair value on the date of grant and recognition of compensation over the service period for awards expected to vest. Cliff Vesting is used and awards vest on the last day of the vesting period. The fair value of stock options is determined using the Black-Scholes Option Pricing Model. The fair value of common shares issued for services is determined based on the Company's stock price on the date of issuance.

Share-based compensation for non-employees in exchange for goods and services used or consumed in an entity's own operations are also recorded at fair value on the measurement date and accounted for in accordance with ASC 718. The measurement of share-based compensation is subject to periodic adjustment as the underlying instruments vest. The fair value of stock options is estimated using the Black-Scholes Option Pricing Model and the compensation charges are amortized over the vesting period.

**Sales and Marketing**

The Company is currently not selling or marketing any products.

**Inflation**

Although management expects that our operations will be influenced by general economic conditions, we do not believe that inflation had a material effect on our results of operations during the nine months ended September 30, 2025.

**Item 3. Quantitative and Qualitative Disclosure About Market Risk**

As a "smaller reporting company" as defined by Item 10 of Regulation S-K, we are not required to provide information required by this item.

**Item 4: Controls and Procedures**

**Disclosure Controls and Procedures**

Disclosure controls and procedures are controls and other procedures that are designed to ensure that information required to be disclosed in our reports filed or submitted under the 1934 Act is recorded, processed, summarized and reported, within the time periods specified in the Securities and Exchange Commission's rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed in our reports filed under the 1934 Act is accumulated and communicated to management, including our principal executive officer and our principal financial officer, as appropriate, to allow timely decisions regarding required disclosure.

Our management, under the direction of our Chief Executive Officer (who is our principal executive officer), and Chief Financial Officer (who is our principal accounting officer) has evaluated the effectiveness of our disclosure controls and procedures as required by 1934 Act Rule 13a-15(b) as of September 30, 2025 (the end of the period covered by this report). Based on that evaluation, our principal executive officer and our principal accounting officer concluded that these disclosure controls and procedures are not effective as of September 30, 2025 to provide reasonable assurance that information required to be disclosed by the Company in the reports that it files or submits under the 1934 Act is accumulated and communicated to management, including the Chief Executive Officer and the Chief Financial Officer, to allow timely decisions regarding required disclosure and are not effective to provide reasonable assurance that such information is recorded, processed, summarized and reported within the time periods specified by the SEC's rules and forms.

The Company, including its Chief Executive Officer and Chief Financial Officer, does not expect that its internal controls and procedures will prevent or detect all error and all fraud. A control system, no matter how well conceived or operated, can provide only reasonable, not absolute, assurance that the objectives of the control system are met.

**Internal Control Over Financial Reporting**

There were no changes in our internal control over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f) promulgated by the SEC under the 1934 Act) during the nine-months ended September 30, 2025, that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

**PART II - OTHER INFORMATION**

**Item 1. Legal Proceedings**

Other than previously reported, the Company and its management are not aware of any regulatory or legal proceedings or investigations pending involving the Company, any of its subsidiaries or affiliates, or any of their respective officers, directors or employees.

**Item 1A. Risk Factors**

As a "smaller reporting company" as defined by Item 10 of Regulation S-K, we are not required to provide information required by this Item. However, our current risk factors are set forth in our Annual Report on Form 10-K for the year ended December 31, 2024 as filed with the SEC on March 28, 2025.

**Item 2. Unregistered Sales of Equity Securities and Use of Proceeds**

Between July 25, 2025 and September 25, 2025, the Company issued 1,000,000 shares of common stock to accredited investors in a private placement for cash proceeds of $10,000. No solicitation was used in the offering. The Company relied on the exemption from registration available under Section 4(a)(2) of the 1933 Act and/or Rule 506(b) of Regulation D promulgated under the 1933 Act with respect to transactions by an issuer not involving any public offering. No commissions were paid in connection with these issuances of securities. The Company filed a Form D with the SEC on October 2, 2025.

**Item 3. Defaults upon Senior Securities**

None.

**Item 4. Mine Safety Disclosure**

Not applicable.

**Item 5. Other Information**

*Rule 10b5-1 trading arrangements*

 

During the Company's third quarter of 2025, no director or officer adopted or terminated a Rule 10b5-1 trading arrangement or a non-Rule 10b5-1 trading arrangement.

*Amendment to Articles of Incorporation*

 

On September 15, 2025, the Company solicited the consent of the stockholders of the Company (the "Consent Solicitation") to approve an amendment to the Company's Articles of Incorporation to increase the total number of authorized shares of common stock, par value $0.0000053, from 500,000,000 to 600,000,000, as described in the Company's Consent Solicitation Statement included in its definitive proxy statement on Schedule 14A, filed with the Securities and Exchange Commission on September 15, 2025 (the "Consent Solicitation Statement"). Such approval by the stockholders is herein referred to as the "Action."

The Action was approved by the requisite vote of a majority of outstanding shares held by the Company's stockholders as of September 5, 2025 (the "Record Date") for the Consent Solicitation. As of the Record Date, there were 389,080,152 shares of common stock outstanding and entitled to 389,080,152 votes. The Action is described in more detail in the Consent Solicitation Statement.

In the aggregate, stockholders holding 57.1% of the Company's outstanding shares of common stock consented to the Action.

A sufficient number of stockholders consented to approve the Action described above by 5:00 p.m., Eastern Time, on October 6, 2025. As a result, the Consent Solicitation, and the period during which consents could be revoked, concluded as of 5:00 p.m., Eastern Time, on October 6, 2025.

*Issuance of Shares for Services*

On October 24, 2025, the Company issued a total of 1,500,000 shares of common stock to one of its consultants as payment for services rendered. The Company relied on the exemption from registration available under Rule 903 of Regulation S promulgated under the 1933 Act and/or Section 4(a)(2) of the 1933 Act and/or Rule 506(b) of Regulation D promulgated under the 1933 Act with respect to transactions by an issuer not involving any public offering. No commissions were paid in connection with these issuances of securities.

**Item 6. Exhibits**

The following is a complete list of exhibits filed as part of this Form 10-Q. Exhibit numbers correspond to the numbers in the Exhibit Table of Item 601 of Regulation S-K.

**EXHIBIT INDEX**

The following documents are being filed with the Commission as exhibits to this Quarterly Report on Form 10-Q.

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | | **Incorporated by Reference** | **Incorporated by Reference** | **Incorporated by Reference** | |
| <br>**No.** | <br>**Exhibit Description** | **Form** | **Date Filed** | **Number** | **Filed or**<br> **Furnished**<br>**Herewith** |
| 3.1 | [Amended and Restated Articles of Incorporation as filed on February 16, 2022](http://www.sec.gov/Archives/edgar/data/1128189/000107997322000154/ex3x1.htm) | 8-K | 2/14/2022 | 3.1 |  |
| 3.2 | [Amended and Restated Bylaws of the Company as approved on December 20, 2021](http://www.sec.gov/Archives/edgar/data/1128189/000107997321001270/ex3x1.htm) | 8-K | 12/23/2021 | 3.2 |  |
| 3.3 | [Amendment to Articles of Incorporation as filed on October 9, 2025](https://www.sec.gov/Archives/edgar/data/1128189/000107997325001594/ex3x1.htm) | 8-K | 10/10/25 | 3.1 |  |
| 4.1 | [Amended 2017 Stock Option and Stock Bonus Plan](http://www.sec.gov/Archives/edgar/data/1128189/000107997318000616/ex4x1.htm) | 8-K | 11/13/2018 | 4.1 |  |
| 4.2 | [Amendment to Amended 2017 Stock Option and Stock Bonus Plan as approved on July 15, 2019](http://www.sec.gov/Archives/edgar/data/1128189/000107997319000404/ex4x1.htm) | 8-K | 7/17/2019 | 4.1 |  |
| 4.3 | [Amendment to Amended 2017 Stock Option and Stock Bonus Plan as approved on April 6, 2020](http://www.sec.gov/Archives/edgar/data/1128189/000107997320000263/ex4x1.htm) | 8-K | 4/10/2020 | 4.1 |  |
| 4.4 | [Consultant Warrant](http://www.sec.gov/Archives/edgar/data/1128189/000107997323000353/ex4x4.htm) | 10-K | 3/17/2023 | 4.4 |  |
| 4.5 | [Form of Warrant](http://www.sec.gov/Archives/edgar/data/1128189/000107997325000816/ex4x5.htm) | 10-Q | 5/15/2025 | 4.5 |  |
| 10.1 | [Royalty Agreement between the Company and The Governors of the University of Alberta, dated April 8, 2015](http://www.sec.gov/Archives/edgar/data/1128189/000107997315000278/ex10x6.htm) | 10-K | 4/14/2015 | 10.6 |  |
| 10.2 | [Collaborative Research Agreement between the Company and the University of British Columbia, dated May 31, 2016](http://www.sec.gov/Archives/edgar/data/1128189/000107997316001125/ex10x10.htm) | 10-Q | 8/15/2016 | 10.10 |  |
| 10.3 | [Consulting Agreement between the Company and Clarence E. Smith, dated December 30, 2016](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000127/ex10x9.htm) | 10-K | 2/21/2017 | 10.9 |  |
| 10.4 | [Director Consulting Agreement between the Company and Edward P. McDonough, dated December 30, 2016](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000127/ex10x11.htm) | 10-K | 2/21/2017 | 10.11 |  |
| 10.5 | [Consulting Agreement between the Company and Grant Young, dated December 30, 2016](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000662/ex10x13.htm) | 10-Q | 11/13/2017 | 10.13 |  |
| 10.6 | [First Amendment to Consulting Agreement between Clarence E. Smith and the Company dated September 1, 2017](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000543/ex10x1.htm) | 8-K/A | 9/12/2017 | 10.1 |  |
| 10.7 | [First Amendment to Consulting Agreement between Grant Young and the Company dated September 1, 2017](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000543/ex10x3.htm) | 8-K/A | 9/12/2017 | 10.3 |  |
| 10.8 | [First Amendment to Consulting Agreement between Edward P. McDonough and the Company dated September 1, 2017](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000545/ex10x2.htm) | 8-K/A | 9/12/2017 | 10.2 |  |
| 10.9 | [Consulting Agreement between ProtoKinetix Incorporated and Michael Guzzetta, dated November 14, 2017](http://www.sec.gov/Archives/edgar/data/1128189/000107997317000679/ex10x1.htm) | 8-K | 11/15/2017 | 10.1 |  |
| 31.1 | [Certification of the Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002](ex31x1.htm) |  |  |  | Filed |
| 31.2 | [Certification of the Principal Financial Officer and Principal Accounting Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002](ex31x2.htm) |  |  |  | Filed |
| 32.1 | [Certification of the Principal Executive Officer and the Principal Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002](ex32x1.htm) |  |  |  | Furnished, not filed herewith |
| 101.INS | XBRL Instance Document |  |  |  | Filed |
| 101.SCH | XBRL Schema Document |  |  |  | Filed |
| 101.CAL | XBRL Calculation Linkbase Document |  |  |  | Filed |
| 101.DEF | XBRL Definition Linkbase Document |  |  |  | Filed |
| 101.LAB | XBRL Label Linkbase Document |  |  |  | Filed |
| 101.PRE | XBRL Presentation Linkbase Document |  |  |  | Filed |
| 104 | Cover Page Interactive Data File (formatted in Inline XBRL and contained in Exhibit 101) |  |  |  | Filed |

---

**SIGNATURES**

Pursuant to the requirements of Section 12 of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

---

| | |
|:---|:---|
| Date: November 13, 2025 | **PROTOKINETIX, INCORPORATED** |
|  | By: */s/ Clarence E. Smith* |
|  | Clarence E. Smith |
|  | Chief Executive Officer |
|  | By: */s/ Michael R. Guzzetta* |
|  | Michael R. Guzzetta |
|  | Chief Financial Officer |

---

## Exhibit 31.1

EXHIBIT 31.1

**CERTIFICATION OF THE PRINCIPAL EXECUTIVE OFFICER**

**PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002**

I, Clarence E. Smith, certify that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. I have reviewed this Quarterly Report on Form 10-Q of ProtoKinetix, Incorporated for the period ended September 30, 2025;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5. The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

---

| | | |
|:---|:---|:---|
| November 13, 2025 | */s/ Clarence E. Smith* | */s/ Clarence E. Smith* |
|  | Name: | Clarence E. Smith |
|  | Title: | Chief Executive Officer<br> (Principal Executive Officer) |

---

## Exhibit 31.2

EXHIBIT 31.2

**CERTIFICATION OF THE PRINCIPAL FINANCIAL OFFICER**

**PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002**

I, Michael R. Guzzetta, certify that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. I have reviewed this Quarterly Report on Form 10-Q of ProtoKinetix, Incorporated for the period ended September 30, 2025;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5. The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

---

| | | |
|:---|:---|:---|
| November 13, 2025 | /s/ Mike R. Guzzetta | /s/ Mike R. Guzzetta |
|  | Name: | Michael R. Guzzetta |
|  | Title: | Chief Financial Officer<br> (Principal Financial Officer)<br>|

---

## Exhibit 32.1

EXHIBIT 32.1

**CERTIFICATION PURSUANT TO**

**18 U.S.C. §1350, AS ADOPTED PURSUANT TO**

**SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002**

In connection with the Quarterly Report of ProtoKinetix, Incorporated, (the "Company") on Form 10-Q for the period ended September 30, 2025 as filed with the Securities and Exchange Commission on the date hereof (the "Report"), Clarence E. Smith, Chief Executive Officer and Principal Executive Officer of the Company and Michael R. Guzzetta, Chief Financial Officer and Principal Financial Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that, to the best of the undersigned's knowledge and belief:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company as of the dates and for the periods expressed in the Report.

---

| | | |
|:---|:---|:---|
| November 13, 2025 | */s/ Clarence E. Smith* | */s/ Clarence E. Smith* |
|  | Name: | Clarence E. Smith |
|  | Title: | Chairman of the Board and<br> Chief Executive Officer<br> (Principal Executive Officer) |

---

---

| | | |
|:---|:---|:---|
| November 13, 2025 | */s/ Michael R. Guzzetta* | */s/ Michael R. Guzzetta* |
|  | Name: | Michael R. Guzzetta |
|  | Title: | Chief Financial Officer<br> (Principal Financial Officer)<br>|

---

This certification accompanies this Report pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended.