# EDGAR Filing Document

**Accession Number:** 0001792267
**File Stem:** 0001193125-26-262871
**Filing Date:** 2026-6
**Character Count:** 26921
**Document Hash:** abdb0bac87c87068fcbd04dcf372552f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-262871.hdr.sgml**: 20260609

**ACCESSION NUMBER**: 0001193125-26-262871

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260609

**FILED AS OF DATE**: 20260609

**DATE AS OF CHANGE**: 20260609

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Burning Rock Biotech Ltd
- **CENTRAL INDEX KEY:** 0001792267
- **STANDARD INDUSTRIAL CLASSIFICATION:** SERVICES-MEDICAL LABORATORIES [8071]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-39316
- **FILM NUMBER:** 261074492

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** NO. 5 XINGDAO RING ROAD NORTH,
- **STREET 2:** INTERNATIONAL BIO ISLAND
- **CITY:** GUANGZHOU, GUANGDONG
- **PROVINCE COUNTRY:** F4
- **ZIP:** 510005
- **BUSINESS PHONE:** 86 18501641666

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** NO. 5 XINGDAO RING ROAD NORTH,
- **STREET 2:** INTERNATIONAL BIO ISLAND
- **CITY:** GUANGZHOU, GUANGDONG
- **PROVINCE COUNTRY:** F4
- **ZIP:** 510005

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**WASHINGTON, D.C. 20549** 

**FORM 6-K** 

**REPORT OF FOREIGN PRIVATE ISSUER** 

**PURSUANT TO RULE 13a-16 OR 15d-16** 

**UNDER THE SECURITIES EXCHANGE ACT OF 1934** 

**For the month of June 2026** 

**Commission File Number: 001-39316** 

## BURNING ROCK BIOTECH LIMITED
**(Registrant's Name)** 

**No.5 Xingdao Ring Road North, International Bio Island** 

**Guangzhou, Guangdong** 

**People's Republic of China** 

**(Address of principal executive offices)** 

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

Form 20-F ☒ Form 40-F ☐

------

**<u>INCORPORATION BY REFERENCE</u>**

Exhibit 99.1 (excluding the paragraphs under the heading "Non-GAAP Measures," the table under the heading "Burning Rock Biotech Limited Reconciliations of GAAP and Non-GAAP Results," and other discussions on non-GAAP measures therein) of this current report on Form 6-K (the "Report") shall be incorporated by reference into the Company's registration statements on Form F-3, which became effective on September 30, 2022 (File no. 333-264577).

------

**EXHIBIT INDEX** 

---

| | |
|:---|:---|
| **Number** | **Description of Document** |
| Exhibit 99.1 | [Press release](d150762dex991.htm) |

---

------

**SIGNATURES** 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

---

| | |
|:---|:---|
| Burning Rock Biotech Limited | Burning Rock Biotech Limited |
| By: | /s/ Yusheng Han |
| Name: | Yusheng Han |
| Title: | Chief Executive officer |

---

Date: June 9, 2026

## Exhibit 99.1

**Exhibit 99.1** 

**Burning Rock Reports First Quarter 2026 Financial Results** 

GUANGZHOU, China, June 9, 2026—Burning Rock Biotech Limited (NASDAQ: BNR, the "Company" or "Burning Rock"), a company focused on the application of next-generation sequencing (NGS) technology in the field of precision oncology, today reported financial results for the three months ended March 31, 2026.

**Recent Business Updates** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Early Detection, Therapy Selection & MRD

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Presented multiple study results at the 2026 AACR in April, showcasing validation data on MMcall, CanCatch Surf, 25-plex ddPCR, and SPIRAL.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Presented study results at *Journal for ImmunoTherapy of Cancer* in April 2026. "A four-cycle
perioperative regimen of serplulimab combined with taxane-carboplatin demonstrated promising MPR and pCR rates with an acceptable safety profile in patients with resectable sq-NSCLC."

**First Quarter 2026 Financial Results** 

Revenues were RMB107.9 million (US$15.6 million) for the three months ended March 31, 2026, representing an 18.9% decrease from RMB133.1 million for the same period in 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Revenue generated from central laboratory business was RMB32.3 million (US$4.7 million) for the three months
ended March 31, 2026, representing a 15.3% decrease from RMB38.3 million for the same period in 2025, primarily attributable to a decrease in the number of tests, as we continued our transition towards in-hospital testing.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Revenue generated from in-hospital business was RMB52.8 million
(US$7.6 million) for the three months ended March 31, 2026, representing an 8.5% decrease from RMB57.7 million for the same period in 2025, primarily attributable to a decrease in revenue from two hospitals due to one-off issue. Excluding such two, in-hospital revenue for the three months ended March 31, 2026 would have increased by 2% year-over-year.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Revenue generated from pharma research and development services was RMB22.8 million (US$3.3 million) for the
three months ended March 31, 2026, representing a 38.6% decrease from RMB37.1 million for the same period in 2025, primarily attributable to decreased testing services performed for our pharma customers and lower milestone progress of our
pharma programs achieved due to timing of the projects.

Cost of revenues was RMB29.9 million (US$4.3 million) for the three months ended March 31, 2026, representing a 16.1% decrease from RMB35.7 million for the same period in 2025.

Gross profit was RMB78.0 million (US$11.3 million) for the three months ended March 31, 2026, representing a 19.9% decrease from RMB97.4 million for the same period in 2025. Gross margin was 72.3% for the three months ended March 31, 2026, compared to 73.2% for the same period in 2025. By channel, gross margin of central laboratory business was 88.7% for the three months ended March 31, 2026, compared to 84.1% during the same period in 2025, primarily driven by a reduction in inventory write-downs; gross margin of in-hospital business was 72.9% for the three months ended March 31, 2026, compared to 76.1% during the same period in 2025, primarily attributable to a decrease in sales volume to high margin products; gross margin of pharma research and development services was 47.4% for the three months ended March 31, 2026, compared to 57.5% during the same period of 2025, primarily due to a decrease in test volume of higher-margin projects.

Non-GAAP gross profit, which excludes depreciation and amortization expenses, was RMB80.5 million (US$11.7 million) for the three months ended March 31, 2026, representing a 20.0% decrease from RMB100.7 million for the same period in 2025. Non-GAAP gross margin was 74.6% for the three months ended March 31, 2026, compared to 75.6% for the same period in 2025. For more details on these non-GAAP financial measures, please see the table captioned "Reconciliations of GAAP and Non-GAAP Results" set forth at the end of this press release.

------

Operating expenses were RMB96.9 million (US$14.1 million) for the three months ended March 31, 2026, representing a 14.0% decrease from RMB112.6 million for the same period in 2025. The decrease was primarily driven by business cost and payment collection control to improve operating efficiency.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Research and development expenses were RMB27.6 million (US$4.0 million) for the three months ended
March 31, 2026, representing a 31.8% decrease from RMB40.4 million for the same period in 2025, primarily due to (i) a temporary decrease across different research phases, and (ii) a decrease in amortized expense on share-based
compensation.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Selling and marketing expenses were RMB41.2 million (US$6.0 million) for the three months ended
March 31, 2026, remaining relatively stable as compared with RMB40.9 million for the same period in 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• General and administrative expenses were RMB28.1 million (US$4.1 million) for the three months ended
March 31, 2026, representing a 10.3% decrease from RMB31.3 million for the same period in 2025, primarily due to a decrease in impairment expenses for accounts receivables and contract assets.

Net loss was RMB17.5 million (US$2.5 million) for the three months ended March 31, 2026, compared to RMB13.5 million for the same period in 2025.

Cash, cash equivalents and restricted cash were RMB448.7 million (US$65.1 million) as of March 31, 2026.

------

**Exchange Rate Information** 

This press release contains translations of certain Renminbi amounts into U.S. dollars at a specified rate solely for the convenience of the reader. Unless otherwise noted, all translations from Renminbi to U.S. dollars and from U.S. dollars to Renminbi are made at a rate of RMB6.8980 to US$1.00, the exchange rate on March 31, 2026, set forth in the H.10 statistical release of the Federal Reserve Board. The Company makes no representation that the Renminbi or U.S. dollars amounts referred could be converted into U.S. dollars or Renminbi, as the case may be, at any particular rate or at all.

**About Burning Rock** 

Burning Rock Biotech Limited (NASDAQ: BNR), whose mission is to guard life via science, focuses on the application of next generation sequencing (NGS) technology in the field of precision oncology. Its business consists of i) NGS-based therapy selection testing for late-stage cancer patients, and ii) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage.

For more information about Burning Rock, please visit: ir.brbiotech.com.

**Safe Harbor Statement** 

This press release contains forward-looking statements. These statements constitute "forward-looking" statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," "target," "confident" and similar statements. Burning Rock may also make written or oral forward-looking statements in its periodic reports to the SEC, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about Burning Rock's beliefs and expectations, are forward-looking statements. Such statements are based upon management's current expectations and current market and operating conditions, and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond Burning Rock's control. Forward-looking statements involve risks, uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. All information provided in this press release is as of the date of this press release, and Burning Rock does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under applicable law.

------

**Non-GAAP Measures** 

In evaluating the business, the Company considers and uses non-GAAP measures, such as non-GAAP gross profit and non-GAAP gross margin, as supplemental measures to review and assess operating performance and formulate business plans. However, the presentation of these non-GAAP financial measures is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with accounting principles generally accepted in the United States of America ("U.S. GAAP"). These non-GAAP financial measures may be different from non-GAAP methods of accounting and reporting used by other companies, including peer companies, and therefore their comparability may be limited.

The Company defines non-GAAP gross profit as gross profit excluding depreciation and amortization. The Company defines non-GAAP gross margin as non-GAAP gross profit divided by its revenue.

The Company believes presenting non-GAAP gross profit and non-GAAP gross margin excluding non-cash impact of depreciation and amortization, in addition to the Company's GAAP gross profit and gross margin, provides a better understanding of the underlying trends in the Company's operating business performance.

Reconciliation of these non-GAAP financial measures to the most directly comparable U.S. GAAP measures are set forth at the end of this press release, all of which should be considered when evaluating the Company's performance.

Contact: IR@brbiotech.com

------

**Selected Operating Data** 

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **As of** | **As of** | **As of** | **As of** | **As of** |
|  | **March 31,**<br>**2025** | **June 30,**<br>**2025** | **September**<br>**30, 2025** | **December**<br>**31, 2025** | **March 31,**<br>**2026** |
|  **In-hospital channel:** |  |  |  |  |  |
|  Pipeline partner hospitals<sup>(1)</sup> | 30 | 30 | 31 | 30 | 30 |
|  Contracted partner hospitals<sup>(2)</sup> | 63 | 63 | 63 | 64 | 64 |
|  **Total number of partner hospitals** | **93** | **93** | **94** | **94** | **94** |

---

<sup>(1)</sup> Refers to hospitals that are in the process of establishing in-hospital laboratories, laboratory equipment procurement or installation, staff training or pilot testing using the Company's products.

<sup>(2)</sup> Refers to hospitals that have entered into contracts to purchase the Company's products for use on a recurring basis in their respective in-hospital laboratories the Company helped them establish. Kit revenue is generated from contracted hospitals.

------

**Selected Financial Data** 

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,** | **June 30,** | **September** | **December** | **March 31,** |
| **Revenues** | **2025** | **2025** | **30, 2025** | **31, 2025** | **2026** |
|  |  | **(RMB in thousands)** | **(RMB in thousands)** | **(RMB in thousands)** |  |
|  Central laboratory channel | 38296 | 40861 | 36811 | 44025 | 32420 |
|  In-hospital channel | 57687 | 62496 | 52847 | 51005 | 52761 |
|  Pharma research and development channel | 37099 | 45197 | 41959 | 31285 | 22762 |
|  **Total revenues** | **133082** | **148554** | **131617** | **126315** | **107943** |

---

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,** | **June 30,** | **September** | **December** | **March 31,** |
| **Revenues by location of contracting customer** | **2025** | **2025** | **30, 2025** | **31, 2025** | **2026** |
|  |  | **(RMB in thousands)** | **(RMB in thousands)** | **(RMB in thousands)** |  |
|  Overseas | 24407 | 37458 | 17214 | 21849 | 8544 |
|  Chinese mainland | 108675 | 111096 | 114403 | 104466 | 99399 |
|  **Total revenues** | **133082** | **148554** | **131617** | **126315** | **107943** |

---

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,** | **June 30,** | **September** | **December** | **March 31,** |
| **Gross profit** | **2025** | **2025** | **30, 2025** | **31, 2025** | **2026** |
|  |  | **(RMB in thousands)** | **(RMB in thousands)** | **(RMB in thousands)** |  |
|  Central laboratory channel | 32191 | 35937 | 30126 | 39322 | 28761 |
|  In-hospital channel | 43895 | 46490 | 37925 | 38388 | 38458 |
|  Pharma research and development channel | 21315 | 25676 | 30793 | 20856 | 10789 |
|  **Total gross profit** | **97401** | **108103** | **98844** | **98566** | **78008** |

---

------

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,** | **June 30,** | **September** | **December** | **March 31,** |
| **Share-based compensation expenses** | **2025** | **2025** | **30, 2025** | **31, 2025** | **2026** |
|  |  | **(RMB in thousands)** | **(RMB in thousands)** | **(RMB in thousands)** |  |
|  Cost of revenues | 308 | 280 | 301 | 300 | 82 |
|  Research and development expenses | 1800 | (270) | 73 | 259 | (345) |
|  Selling and marketing expenses | 1025 | 364 | 624 | 748 | 164 |
|  General and administrative expenses | 1413 | 2005 | 2831 | 1815 | 1907 |
|  **Total share-based compensation expenses** | **4546** | **2379** | **3829** | **3122** | **1808** |

---

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**Burning Rock Biotech Limited** 

**Unaudited Condensed Statements of Comprehensive Loss** 

*(in thousands, except for number of shares and per share data)* 

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,**<br>**2025** | **June 30,**<br>**2025** | **September**<br>**30, 2025** | **December**<br>**31, 2025** | **March 31,**<br>**2026** | **March 31,**<br>**2026** |
|  | **RMB** | **RMB** | **RMB** | **RMB** | **RMB** | **US$** |
|  **Revenues** | **133082** | **148554** | **131617** | **126315** | **107943** | **15649** |
|  **Cost of revenues** | **(35681)** | **(40451)** | **(32773)** | **(27749)** | **(29935)** | **(4339)** |
|  **Gross profit** | **97401** | **108103** | **98844** | **98566** | **78008** | **11310** |
|  **Operating expenses:** |  |  |  |  |  |  |
|  Research and development expenses | (40389) | (49770) | (41469) | (34866) | (27559) | (3995) |
|  Selling and marketing expenses | (40888) | (38413) | (41808) | (44066) | (41206) | (5974) |
|  General and administrative expenses | (31303) | (31417) | (31698) | (31672) | (28088) | (4072) |
|  **Total operating expenses** | **(112580)** | **(119600)** | **(114975)** | **(110604)** | **(96853)** | **(14041)** |
|  **Loss from operations** | **(15179)** | **(11497)** | **(16131)** | **(12038)** | **(18845)** | **(2731)** |
|  Interest income | 2581 | 2226 | 1744 | 1502 | 1261 | 183 |
|  Interest expense |  |  | (15) | (15) | (15) | (2) |
|  Other (expense) income, net | (652) | 387 | 7 | 1 | 294 | 43 |
|  Foreign exchange (loss) gain, net | (26) | (574) | (2151) | (3960) | 65 | 9 |
|  **Loss before income tax** | **(13276)** | **(9458)** | **(16546)** | **(14510)** | **(17240)** | **(2498)** |
|  Income tax expenses | (224) | (244) | (212) | (876) | (232) | (34) |
|  **Net loss** | **(13500)** | **(9702)** | **(16758)** | **(15386)** | **(17472)** | **(2532)** |
|  **Net loss attributable to Burning Rock Biotech Limited's shareholders** | **(13500)** | **(9702)** | **(16758)** | **(15386)** | **(17472)** | **(2532)** |
|  **Net loss attributable to ordinary shareholders** | **(13500)** | **(9702)** | **(16758)** | **(15386)** | **(17472)** | **(2532)** |
|  **Loss per share for class A and class B ordinary shares:** |  |  |  |  |  |  |
|  Class A ordinary shares - basic and diluted | (0.13) | (0.09) | (0.16) | (0.15) | (0.17) | (0.02) |
|  Class B ordinary shares - basic and diluted | (0.13) | (0.09) | (0.16) | (0.15) | (0.17) | (0.02) |
|  **Weighted average shares outstanding used in loss per share computation:** |  |  |  |  |  |  |
|  Class A ordinary shares - basic and diluted | 90291658 | 90357970 | 90416619 | 87444109 | 87871026 | 87871026 |
|  Class B ordinary shares - basic and diluted | 17324848 | 17324848 | 17324848 | 17324848 | 17324848 | 17324848 |
|  **Other comprehensive loss, net of tax of nil:** |  |  |  |  |  |  |
|  Foreign currency translation adjustments | (72) | (243) | (1724) | (2050) | (3143) | (456) |
|  **Total comprehensive loss** | **(13572)** | **(9945)** | **(18482)** | **(17436)** | **(20615)** | **(2988)** |
|  **Total comprehensive loss attributable to Burning Rock Biotech Limited's shareholders** | **(13572)** | **(9945)** | **(18482)** | **(17436)** | **(20615)** | **(2988)** |

---

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**Burning Rock Biotech Limited** 

**Unaudited Condensed Consolidated Balance Sheets** 

*(In thousands)*

---

| | | | |
|:---|:---|:---|:---|
|  | **As of** | **As of** | **As of** |
|  | **December 31,**<br>**2025** | **March 31,**<br>**2026** | **March 31,**<br>**2026** |
|  | **RMB** | **RMB** | **US$** |
|  **ASSETS** |  |  |  |
|  **Current assets:** |  |  |  |
|  Cash and cash equivalents | 478392 | 446002 | 64657 |
|  Restricted cash | 2696 | 2728 | 395 |
|  Accounts receivable, net | 169611 | 164497 | 23847 |
|  Contract assets, net | 12301 | 12715 | 1843 |
|  Inventories, net | 56975 | 54294 | 7871 |
|  Prepayments and other current assets | 18611 | 20759 | 3010 |
|  **Total current assets** | **738586** | **700995** | **101623** |
|  **Non-current assets:** |  |  |  |
|  Property and equipment, net | 31099 | 26997 | 3914 |
|  Operating right-of-use assets | 42774 | 51931 | 7528 |
|  Intangible assets, net | 284 | 258 | 37 |
|  Other non-current assets | 7632 | 7603 | 1102 |
|  **Total non-current assets** | **81789** | **86789** | **12581** |
|  **TOTAL ASSETS** | **820375** | **787784** | **114204** |

---

------

**Burning Rock Biotech Limited** 

**Unaudited Condensed Consolidated Balance Sheets (Continued)** 

*(in thousands)*

---

| | | | |
|:---|:---|:---|:---|
|  | **As of** | **As of** | **As of** |
|  | **December 31,**<br>**2025** | **March 31,**<br>**2026** | **March 31,**<br>**2026** |
|  | **RMB** | **RMB** | **US$** |
|  **LIABILITIES AND SHAREHOLDERS' EQUITY** |  |  |  |
|  **Current liabilities:** |  |  |  |
|  Accounts payable | 40744 | 18043 | 2616 |
|  Deferred revenue | 107819 | 114487 | 16597 |
|  Accrued liabilities and other current liabilities | 80861 | 75381 | 10928 |
|  Customer deposits | 592 | 592 | 86 |
|  Current portion of long-term borrowings | 200 | 200 | 29 |
|  Current portion of operating lease liabilities | 16762 | 21113 | 3061 |
|  **Total current liabilities** | **246978** | **229816** | **33317** |
|  **Non-current liabilities:** |  |  |  |
|  Long-term borrowings | 1700 | 1700 | 246 |
|  Non-current portion of operating lease liabilities | 24458 | 27850 | 4037 |
|  Other non-current liabilities | 11975 | 11961 | 1734 |
|  **Total non-current liabilities** | **38133** | **41511** | **6017** |
|  **TOTAL LIABILITIES** | **285111** | **271327** | **39334** |
|  **Shareholders' equity:** |  |  |  |
|  Class A ordinary shares | 120 | 120 | 17 |
|  Class B ordinary shares | 21 | 21 | 3 |
|  Additional paid-in capital | 5010060 | 5011868 | (8291) |
|  Treasury stock | (57193) | (57193) | 726568 |
|  Accumulated deficits | (4255607) | (4273079) | (619466) |
|  Accumulated other comprehensive loss | (162137) | (165280) | (23961) |
|  **Total shareholders' equity** | **535264** | **516457** | **74870** |
|  **TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY** | **820375** | **787784** | **114204** |

---

------

**Burning Rock Biotech Limited** 

**Unaudited Condensed Statements of Cash Flows** 

*(in thousands)* 

---

| | | | |
|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,**<br>**2025** | **March 31,**<br>**2026** | **March 31,**<br>**2026** |
|  | **RMB** | **RMB** | **US$** |
|  Net cash used in operating activities | (23527) | (29304) | (4248) |
|  Net cash used in investing activities | (1531) | (364) | (53) |
|  Net cash generated from financing activities |  |  |  |
|  Effect of exchange rate on cash, cash equivalents and restricted cash | 302 | (2690) | (390) |
|  **Net decrease in cash, cash equivalents and restricted cash** | **(24756)** | **(32358)** | **(4691)** |
|  Cash, cash equivalents and restricted cash at the beginning of period | 522162 | 481088 | 69743 |
|  **Cash, cash equivalents and restricted cash at the end of period** | **497406** | **448730** | **65052** |

---

------

**Burning Rock Biotech Limited** 

**Reconciliations of GAAP and Non-GAAP Results** 

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** | **For the three months ended** |
|  | **March 31,**<br>**2025** | **June 30,**<br>**2025** | **September**<br>**30, 2025** | **December**<br>**31, 2025** | **March 31,**<br>**2026** |
|  | | **(RMB in thousands)** | **(RMB in thousands)** | **(RMB in thousands)** | |
|  **Gross profit:** |  |  |  |  |  |
|  Central laboratory channel | 32191 | 35937 | 30126 | 39322 | 28761 |
|  In-hospital channel | 43895 | 46490 | 37925 | 38388 | 38458 |
|  Pharma research and development channel | 21315 | 25676 | 30793 | 20856 | 10789 |
|  **Total gross profit** | **97401** | **108103** | **98844** | **98566** | **78008** |
|  **Add: depreciation and amortization:** |  |  |  |  |  |
|  Central laboratory channel | 562 | 456 | 231 | 490 | 412 |
|  In-hospital channel | 290 | 389 | 372 | 308 | 228 |
|  Pharma research and development channel | 2412 | 1528 | 1491 | 2057 | 1885 |
|  **Total depreciation and amortization included in cost of revenues** | **3264** | **2373** | **2094** | **2855** | **2525** |
|  **Non-GAAP gross profit:** |  |  |  |  |  |
|  Central laboratory channel | 32753 | 36393 | 30357 | 39812 | 29173 |
|  In-hospital channel | 44185 | 46879 | 38297 | 38696 | 38686 |
|  Pharma research and development channel | 23727 | 27204 | 32284 | 22913 | 12674 |
|  **Total non-GAAP gross profit** | **100665** | **110476** | **100938** | **101421** | **80533** |
|  **Non-GAAP gross margin:** |  |  |  |  |  |
|  Central laboratory channel | 85.5% | 89.1% | 82.5% | 90.4% | 90.0% |
|  In-hospital channel | 76.6% | 75.0% | 72.5% | 75.9% | 73.3% |
|  Pharma research and development channel | 64.0% | 60.2% | 76.9% | 73.2% | 55.7% |
|  **Total non-GAAP gross margin** | **75.6%** | **74.4%** | **76.7%** | **80.3%** | **74.6%** |

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