# EDGAR Filing Document

**Accession Number:** 0001837493
**File Stem:** 0001213900-26-001862
**Filing Date:** 2026-1
**Character Count:** 34472
**Document Hash:** 5b87fc400c5bbe931350a4979367e786
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-26-001862.hdr.sgml**: 20260106

**ACCESSION NUMBER**: 0001213900-26-001862

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 15

**FILED AS OF DATE**: 20260106

**DATE AS OF CHANGE**: 20260106

**EFFECTIVENESS DATE**: 20260106

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Inspira Technologies OXY B.H.N. Ltd
- **CENTRAL INDEX KEY:** 0001837493
- **STANDARD INDUSTRIAL CLASSIFICATION:** SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000
- **STATE OF INCORPORATION:** L3
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-292592
- **FILM NUMBER:** 26512849

**BUSINESS ADDRESS:**
- **STREET 1:** HATIDHAR 2
- **STREET 2:** 11TH FLOOR
- **CITY:** RA'ANANA
- **STATE:** L3
- **ZIP:** 4366504
- **BUSINESS PHONE:** 972-9-9664488

**MAIL ADDRESS:**
- **STREET 1:** HATIDHAR 2
- **STREET 2:** 11TH FLOOR
- **CITY:** RA'ANANA
- **STATE:** L3
- **ZIP:** 4366504

**As filed with the Securities and Exchange Commission on January 6, 2026**

**Registration No. 333 -** 

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**WASHINGTON, D.C. 20549**

**FORM S-8**

**REGISTRATION STATEMENT**

**UNDER**

**THE SECURITIES ACT OF 1933**

**INSPIRA TECHNOLOGIES OXY B.H.N. LTD.**

(Exact name of registrant as specified in its charter)

---

| | |
|:---|:---|
| **State of Israel** | **Not applicable** |
| (State or other jurisdiction of<br> incorporation or organization) | (I.R.S. Employer <br> Identification No.) |

---

**2 Ha-Tidhar St., Ra'anana, 4366504 Israel**

(Address of Principal Executive Offices)

**Inspira Technologies OXY B.H.N. LTD.** 

**Amended and Restated 2019 Equity Incentive Plan**

(Full title of the plan)

**Puglisi & Associates**

**850 Library Ave., Suite 204, Newark, DE 19711**

**Tel: (302) 738-6680** 

(Name, Address and Telephone Number of Agent for Service)

COPIES TO:

---

| | |
|:---|:---|
| Oded Har-Even, Esq.<br> Ron Ben-Bassat, Esq.<br> Sullivan & Worcester LLP<br> 1251 Avenue of the Americas<br> New York, NY 10020<br> Tel: (212)-660-3000 | Adv. Reut Alfiah<br> Adv. Gal Cohen<br> Sullivan & Worcester Tel-Aviv (Har-Even & Co.)<br> 28 HaArba'a St. HaArba'a Towers<br> North Tower, 35th floor<br> Tel-Aviv, Israel 6473925<br> Tel: +972 74-758-0480 |

---

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See definitions of "large accelerated filer," "accelerated filer," "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act.

Large accelerated filer ☐ Accelerated filer ☐ <br> Non-accelerated filer ☒ Smaller reporting company ☐ <br> Emerging growth company ☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

**EXPLANATORY NOTE**

On August 5, 2021, Inspira Technologies Oxy B.H.N. Ltd., or the Registrant or the Company, filed a Registration Statement on Form S-8 (File No. 333-259057), or the Original Registration Statement, with the Securities and Exchange Commission, or the SEC, to register an aggregate of 4,180,898 ordinary shares, no par value per share, of the Company, or the Ordinary Shares, that may be issued pursuant to the Company's 2019 Equity Incentive Plan, or the 2019 Plan. On March 15, 2024, the Company filed an additional Registration Statement on Form S-8 (File No. 333-277980) with the SEC to register an additional 2,997,671 Ordinary Shares that may be issued pursuant to the 2019 Plan. On March 5, 2025, the Company filed an additional Registration Statement on Form S-8 (File No. 333-285565) with the SEC to register an additional 3,000,000 Ordinary Shares that may be issued pursuant to the 2019 Plan. On September 10, 2025, the Company filed an additional Registration Statement on Form S-8 (File No. 333-290162) with the SEC to register an additional 1,184,910 Ordinary Shares that may be issued pursuant to the 2019 Plan.

The 2019 Plan was originally adopted by the board of directors of the Company in November 2019, amended in September 2021, and further amended and restated in March 2025, or the Amended and Restated 2019 Plan.

The Company is filing this Registration Statement on Form S-8, or this Registration Statement, to register an additional 512,498 Ordinary Shares reserved for issuance in connection with securities awards which may hereafter be granted under the Amended and Restated 2019 Plan.

Pursuant to General Instruction E to Form S-8, the contents of the Original Registration Statement are incorporated herein by reference, except for Items 3 and 8 of Part II of the Original Registration Statement, which are being updated by this Registration Statement.

**PART I**

**INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS**

The information specified in Item 1 and Item 2 of Part I of Form S-8 is omitted from this Registration Statement. The documents containing the information specified in Part I of Form S-8 will be delivered to the participants in the Plan covered by this Registration Statement as specified by Rule 428(b)(1) under the Securities Act of 1933, as amended, or the Securities Act.

**PART II**

**ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE**

The following documents filed by the Company with the SEC are incorporated by reference into this Registration Statement:

● Our Annual Report on Form 20-F for the fiscal year ended December 31, 2024, filed with the SEC on [March 10, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025022325/ea0233226-20f_inspira.htm) and as amended on [March 28, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000101376225004105/ea0235908-20fa1_inspira.htm) ;

● Our Reports on Form 6-K furnished on [March 11, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025022474/ea0233937-6k_inspira.htm) (with respect to the first paragraph, the sections titled "Recent Business and Operational Highlights," "Full Year 2024 Financial Results" and "Forward-Looking Statements" of the press release attached therewith as Exhibit 99.1), [March 13, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025023722/ea0234133-6k_inspira.htm) , [March 14, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000101376225000316/ea0234433-6k_inspira.htm) , [March 14, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025024178/ea0234381-6k_inspira.htm) , [March 25, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000101376225001866/ea0235570-6k_inspira.htm) (with respect to the first, second, fourth, and fifth paragraphs and the section titled "Forward-Looking Statements"), [April 7, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025029402/ea0237333-6k_inspira.htm) (with respect to the first, second, and fifth paragraphs and the section titled "Forward-Looking Statements"), [April 10, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025030673/ea0237837-6k_inspira.htm) , [April 15, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025031782/ea0238307-6k_inspira.htm) (with respect to the first, second, and fourth paragraphs and the section titled "Forward-Looking Statements"), [April 23, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025034345/ea0239203-6k_inspira.htm) (with respect to the first three and fifth paragraphs and the section titled "Forward-Looking Statements"), [May 7, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025040436/ea0241039-6k_inspira.htm) (with respect to the first three and fifth paragraphs and the section titled "Forward-Looking Statements"), [May 12, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025042012/ea0241780-6k_inspira.htm) , [May 27, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025047792/ea0243475-6k_inspira.htm) (with respect to the first, second, fifth and sixth paragraphs and the section titled "Forward-Looking Statements"), [May 29, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025048546/ea0243804-6k_inspira.htm) (with respect to the first, second, fourth, fifth and sixth paragraphs and the section titled "Forward-Looking Statements"), [May 30, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025049456/ea0244032-6k_inspira.htm) , [June 5, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025051371/ea0244808-6k_inspira.htm) (with respect to the first, second, fourth and fifth paragraphs and the section titled "Forward-Looking Statements"), [June 11, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025053290/ea0245402-6k_inspira.htm) , [June 23, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025056713/ea0246042-6k_inspira.htm) , [July 1, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025060005/ea0247647-6k_inspira.htm) , [July 2, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025060734/ea0247978-6k_inspira.htm) (with respect to the first, second, and fifth paragraphs and the section titled "Forward-Looking Statements"), [July 7, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025061642/ea0248259-6k_inspira.htm) (with respect to the first three paragraphs and the section titled "Forward-Looking Statements"), [July 10, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025062552/ea0248531-6k_inspira.htm) (with respect to the first two paragraphs and the section titled "Forward-Looking Statements"), [July 17, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025065216/ea0249344-6k_inspira.htm) , [July 18, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025065343/ea0249471-6k_inspira.htm) (with respect to the first two paragraphs and the section titled "Forward-Looking Statements"), [July 31, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025069677/ea0250593-6k_inspiratech.htm) (with respect to the first, second, and fourth paragraphs and the section titled "Forward-Looking Statements"); [August 19, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025078166/ea0253746-6k_inspira.htm) (with respect to the first, second, and fourth paragraphs and the section titled "Forward-Looking Statements"), [August 22, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025079586/ea0254314-6k_inspira.htm) (with respect to the first, second, and fourth paragraphs and the section titled "Forward-Looking Statements") [September 2, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025082964/ea0255477-6k_inspira.htm) (with respect to the first, second, and fourth paragraphs and the section titled "Forward-Looking Statements"); [September 11, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025086686/ea0256773-6k_inspira.htm) (with respect to the first four paragraphs and the section titled "Forward-Looking Statements"), [September 16, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025088226/ea0257602-6k_inspira.htm) ; [September 18, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025088772/ea0257867-6k_inspira.htm) (with respect to the first, second, third and fifth paragraphs and the section titled "Forward-Looking Statements"), [October 1, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025094366/ea0254604-6k_inspira.htm) ; [October 21, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025100779/ea0261918-6k_inspira.htm) (with respect to the first, second and third paragraphs and the section titled "Forward-Looking Statements"), [October 22, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025100992/ea0262097-6k_inspira.htm) (with respect to the first four paragraphs and the section titled "Forward-Looking Statements"), [November 6, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025106864/ea0264336-6k_inspira.htm) (with respect to the first, second, and fourth paragraphs and the section titled "Forward-Looking Statements"), [November 13, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025109624/ea0265512-6k_inspira.htm) (with respect to the first three and the fifth paragraphs and the section titled "Forward-Looking Statements"), [November 25, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025114738/ea0267190-6k_inspira.htm) , [December 3, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025117583/ea0268296-6k_inspira.htm) (with respect to the first four and the sixth paragraphs and the section titled "Forward-Looking Statements"), [December 9, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025119455/ea0268975-6k_inspira.htm) (with respect to the first three paragraphs and the section titled "Forward-Looking Statement Disclaimer") [December 15, 2025](https://www.sec.gov/Archives/edgar/data/1837493/000121390025121495/ea0269648-6k_inspira.htm) ; [December 23, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025124911/ea0270781-6k_inspira.htm) ; [December 31, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025127105/ea0271409-6k_inspira.htm) ; and [January 5, 2026](http://www.sec.gov/Archives/edgar/data/1837493/000121390026000794/0001213900-26-000794-index.htm) ; and

● The description of our securities contained in [Exhibit 2.1](http://www.sec.gov/Archives/edgar/data/1837493/000121390024025316/ea020216701ex2-1_inspira.htm) to our Annual Report on Form 20-F for the fiscal year ended December 31, 2024, filed with the SEC on [March 10, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000121390025022325/ea0233226-20f_inspira.htm) , and as amended on [March 28, 2025](http://www.sec.gov/Archives/edgar/data/1837493/000101376225004105/ea0235908-20fa1_inspira.htm) .

In addition to the foregoing, all documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act and all reports on Form 6-K subsequently filed by the Registrant which state that they are incorporated by reference herein, prior to the filing of a post-effective amendment which indicates that all securities offered hereunder have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be part hereof from the date of filing of such documents and reports.

Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement herein, or in any subsequently filed document which also is or is deemed to be incorporated by reference, modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.

---

| | |
|:---|:---|
| **ITEM 6.** | **INDEMNIFICATION OF DIRECTORS AND OFFICERS** |

---

 **

***Indemnification***

 **

The Israeli Companies Law, 5759-1999, or the Companies Law, and the Israeli Securities Law, 5728-1968, or the Securities Law, provide that a company may indemnify an office holder against the following liabilities and expenses incurred for acts performed by him or her as an office holder, either pursuant to an undertaking made in advance of an event or following an event, provided its articles of association include a provision authorizing such indemnification:

● a financial liability imposed on him or her in favor of another person by a judgment concerning an act performed in his or her capacity as an office holder, including a settlement or arbitrator's award approved by a court;

● reasonable litigation expenses, including attorneys' fees, expended by the office holder (a) as a result of an investigation or proceeding instituted against him or her by an authority authorized to conduct such investigation or proceeding, provided that (1) no indictment was filed against such office holder as a result of such investigation or proceeding; and (2) no financial liability as a substitute for the criminal proceeding (as defined in the Companies Law) was imposed upon him or her as a result of such investigation or proceeding, or, if such financial liability was imposed, it was imposed with respect to an offense that does not require proof of criminal intent; or (b) in connection with a monetary sanction;

● reasonable litigation expenses, including attorneys' fees, expended by the office holder or imposed on him or her by a court: (1) in proceedings that the company institutes, or that are instituted on the company's behalf, or by another person, against him or her; (2) in a criminal proceeding of which he or she was acquitted; or (3) as a result of a conviction for a crime that does not require proof of criminal intent; and

● expenses incurred by an office holder in connection with an Administrative Procedure under the Securities Law, including reasonable litigation expenses and reasonable attorneys' fees. An "Administrative Procedure" is defined as a procedure pursuant to chapters H3 (Monetary Sanction by the Israeli Securities Authority), H4 (Administrative Enforcement Procedures of the Administrative Enforcement Committee) or I1 (Arrangement to prevent Procedures or Interruption of procedures subject to conditions) to the Securities Law.

The Companies Law also permits, if a company adds provisions in the articles of association, to undertake in advance to indemnify an office holder, provided that if such indemnification relates to financial liability imposed on him or her, as described above, then the undertaking should be limited and shall detail the following foreseen events and amount or criterion:

● to events that in the opinion of the board of directors can be foreseen based on the company's activities at the time that the undertaking to indemnify is made; and

● in amount or criterion determined by the board of directors, at the time of the giving of such undertaking to indemnify, to be reasonable under the circumstances.

We have entered into indemnification agreements with all of our directors and with all members of our senior management. Each such indemnification agreement provides the office holder with indemnification permitted under applicable law and up to a certain amount, and to the extent that these liabilities are not covered by directors' and officers' insurance.

 **

***Insurance***

 **

Under the Companies Law, a company may obtain insurance for any of its office holders against the following liabilities incurred due to acts he or she performed as an office holder, if and to the extent provided for in the company's articles of association:

● breach of his or her duty of care to the company or to another person, to the extent such a breach arises out of the negligent conduct of the office holder;

● a breach of his or her duty of loyalty to the company, provided that the office holder acted in good faith and had reasonable cause to assume that his or her act would not prejudice the company's interests; and

● a financial liability imposed upon him or her in favor of another person.

***Exemption***

 ****

Under the Companies Law, an Israeli company may not exempt an office holder from liability for a breach of his or her duty of loyalty, but may exempt in advance an office holder from his or her liability to the company, in whole or in part, for damages caused to the company as a result of a breach of his or her duty of care (other than in relation to distributions), but only if a provision authorizing such exemption is included in its articles of association. Our amended and restated articles of association and our indemnification agreements provide that we may exempt, in whole or in part, any office holder from liability to us for damages caused to the company as a result of a breach of his or her duty of care. Subject to the aforesaid limitations, under the indemnification agreements, we exempt and release our office holders from any and all liability to us related to any breach by them of their duty of care to us to the fullest extent permitted by law, while acting in good faith and having reasonable cause to assume that such act or omission would not prejudice the interests of the Company, provided that the indemnitee shall not be exempt with respect to any action or omission as to which, under applicable law, the Company is not entitled to exempt the indemnitee.

 

***Limitations***

 ****

The Companies Law provides that the Company may not exempt or indemnify an office holder nor enter into an insurance contract that would provide coverage for any liability incurred as a result of any of the following: (1) a breach by the office holder of his or her duty of loyalty unless (in the case of indemnity or insurance only, but not exemption) the office holder acted in good faith and had a reasonable basis to believe that the act would not prejudice us; (2) a breach by the office holder of his or her duty of care if the breach was carried out intentionally or recklessly (as opposed to merely negligently); (3) any act or omission committed with the intent to derive an illegal personal benefit; or (4) any fine, monetary sanction, penalty or forfeit levied against the office holder.

Under the Companies Law, exemption, indemnification and insurance of office holders in a public company must be approved by the compensation committee and the board of directors)and, with respect to directors and the chief executive officer, by the shareholders). However, under regulations promulgated under the Companies Law, the insurance of office holders shall not require shareholder approval and may be approved by only the compensation committee, if the engagement terms are determined in accordance with the company's compensation policy that was approved by the shareholders by the same special majority required to approve a compensation policy, provided that the insurance policy is on market terms and the insurance policy is not likely to materially impact the company's profitability, assets or obligations. In addition, under regulations promulgated under the Companies Law, the insurance of office holders of a company in which there is a controlling shareholder who is also an office holder, a board approval is also required, subject to meeting the aforesaid conditions.

Our amended and restated articles of association permit us to exempt (subject to the aforesaid limitation), indemnify and insure our office holders to the fullest extent permitted or to be permitted by the Companies Law.

---

| | |
|:---|:---|
| **Item 8.** | **Exhibits.** |
| 4.1 | [Amended and Restated Articles of Association of Inspira Technologies Oxy B.H.N. Ltd. (incorporated by reference to Exhibit 99.1 to the Company's Report on Form 6-K (File No. 001-40303) filed on December 20, 2021).](http://www.sec.gov/Archives/edgar/data/1837493/000121390021066318/ea152692ex99-1_inspiratech.htm) |
| 5.1\* | [Opinion of Sullivan & Worcester Tel Aviv (Har-Even & Co.)](ea027200701ex5-1_inspira.htm) |
| 23.1\* | [Consent of Ziv Haft, member firm of BDO, independent registered public accounting firm.](ea027200701ex23-1_inspira.htm) |
| 23.2\* | [Consent of Sullivan & Worcester Tel Aviv (Har-Even & Co.) (included in the opinion filed as Exhibit 5.1 to this Registration Statement)](ea027200701ex5-1_inspira.htm) |
| 24.1\* | [Power of Attorney (included on signature page)](#pow_001) |
| 99.1 | [Amended and Restated Inspira Technologies Oxy B.H.N. Ltd. 2019 Equity Incentive Plan (incorporated by reference to Exhibit 99.1 to the Company's Form S-8 (File No. 333-285565) filed on March 5, 2025).](http://www.sec.gov/Archives/edgar/data/1837493/000121390025020699/ea023315301ex99-1_inspira.htm) |
| 107\* | [Filing Fee Table.](ea027200701ex-fee_inspira.htm) |

---

\* Filed herewith.

**SIGNATURES**

Pursuant to the requirements of the Securities Act, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement on Form S-8 to be signed on its behalf by the undersigned, thereunto duly authorized, in Ra'anana, Israel, on January 6, 2026.

---

| | | |
|:---|:---|:---|
| **INSPIRA TECHNOLOGIES OXY B.H.N. LTD.** | **INSPIRA TECHNOLOGIES OXY B.H.N. LTD.** | **INSPIRA TECHNOLOGIES OXY B.H.N. LTD.** |
| By: | /s/ Dagi Ben-Noon | /s/ Dagi Ben-Noon |
|  | Name: | Dagi Ben-Noon |
|  | Title: | Chief Executive Officer |

---

**POWER OF ATTORNEY AND SIGNATURES**

We, the undersigned officers and directors of Inspira Technologies Oxy B.H.N. Ltd., hereby severally constitute and appoint Dagi Ben-Noon and Yafit Tehila, and each of them individually, our true and lawful attorney to sign for us and in our names in the capacities indicated below any and all amendments or supplements, including any post-effective amendments, to this Registration Statement on Form S-8 and to file the same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney full power and authority to do and perform each and every act and thing requisite or necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming our signatures to said amendments to this Registration Statement signed by our said attorney and all else that said attorney may lawfully do and cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act, this Registration Statement on Form S-8 has been signed below by the following persons in the capacities and on the dates indicated.

---

| | | |
|:---|:---|:---|
| **Signature** | **Title** | **Date** |
| /s/ Dagi Ben-Noon | Chief Executive Officer and Director | January 6, 2026 |
| Dagi Ben-Noon | (Principal Executive Officer) |  |
| /s/ Yafit Tehila | Chief Financial Officer | January 6, 2026 |
| Yafit Tehila | (Principal Financial and Accounting Officer) |  |
| /s/ Tal Parnes | Chairman of the Board of Directors | January 6, 2026 |
| Tal Parnes |  |  |
| /s/ Lior Amit | Director | January 6, 2026 |
| Lior Amit |  |  |
| /s/ Sivan Matza | Director | January 6, 2026 |
| Sivan Matza |  |  |

---

**SIGNATURE OF AUTHORIZED REPRESENTATIVE IN THE UNITED STATES**

Pursuant to the Securities Act, the undersigned, Puglisi & Associates, the duly authorized representative in the United States of Inspira Technologies Oxy B.H.N. Ltd., has signed this Registration Statement on Form S-8 on January 6, 2026.

---

| | |
|:---|:---|
| Puglisi & Associates | Puglisi & Associates |
| Authorized U.S. Representative | Authorized U.S. Representative |
| /s/ Donald J. Puglisi | /s/ Donald J. Puglisi |
| Name: | Donald J. Puglisi |
| Title: | Managing Director |

---

## Exhibit 5.1

**Exhibit 5.1**

---

| | | |
|:---|:---|:---|
| ![](ex5-1_001.jpg) | **Sullivan & Worcester Tel Aviv**<br> 28 HaArba'a St. HaArba'a Towers North<br> Tower, 35th Floor<br> Tel-Aviv, Israel  | +972-747580480 sullivanlaw.com |

---

January 6, 2026

To:

Inspira Technologies Oxy B.H.N. Ltd.

2 Ha-Tidhar St.

Ra'anana, 4366504, Israel

---

| | |
|:---|:---|
| Re: |  **<u>Registration Statement on Form S-8</u>** |

---

Ladies and Gentlemen:

We have acted as Israeli counsel for Inspira Technologies Oxy B.H.N. Ltd., an Israeli company (the "**Company**"), in connection with the Registration Statement on Form S-8 (the "**Registration Statement**") filed by the Company on the date hereof with the U.S. Securities and Exchange Commission (the "**SEC**") under the Securities Act of 1933, as amended (the "**Securities Act**"). The Registration Statement relates to the registration of additional 512,498 of the Company's ordinary shares, no par value per share, (the "**Ordinary Shares**"), reserved for issuance in connection with securities awards which may be granted under the Company's Amended and Restated 2019 Equity Incentive Plan (the "**Plan**").

In connection herewith, we have examined the originals, or photocopies or copies, certified or otherwise identified to our satisfaction, of: (i) the Registration Statement to which this opinion is attached as an exhibit; (ii) a copy of the amended and restated articles of association of the Company (the "**Articles**"), as currently in effect; (iii) resolutions of the board of directors which relate to the Registration Statement and the Plan; and (iv) such other corporate records, agreements, documents and other instruments, and such certificates or comparable documents of public officials and of officers and representatives of the Company as we have deemed relevant and necessary as a basis for the opinions hereafter set forth. We have also made inquiries of such officers and representatives as we have deemed relevant and necessary as a basis for the opinions hereafter set forth.

In such examination, we have assumed the genuineness of all signatures, the legal capacity of all natural persons, the authenticity of all documents submitted to us as originals, the conformity to original documents of all documents submitted to us as certified, confirmed as photostatic copies and the authenticity of the originals of such latter documents. As to all questions of fact material to these opinions that have not been independently established, we have relied upon certificates or comparable documents of officers and representatives of the Company. In addition, we have assumed that the Ordinary Shares and any equity awards that provide for the acquisition thereof will be granted in accordance with the Plan and the Articles.

We are members of the Israel Bar Association and we express no opinion as to any matter relating to the laws of any jurisdiction other than the laws of the State of Israel and have not, for the purpose of giving this opinion, made any investigation of the laws of any other jurisdiction than the State of Israel.

Based upon and subject to the foregoing, we are of the opinion that the Ordinary Shares issuable under the Plan have been duly authorized and, when and if issued and paid for in accordance with the terms of the Plan, will be validly issued, fully paid and non-assessable.

We consent to the filing of this opinion as an exhibit to the Registration Statement and to the reference to our firm wherever appearing in the Registration Statement in connection with Israeli law. In giving this consent, we do not thereby admit that we are within the category of persons whose consent is required under Section 7 of the Securities Act, the rules and regulations of the SEC promulgated thereunder or Item 509 of the SEC's Regulation S-K under the Securities Act.

Very truly yours,

---

| |
|:---|
| /s/ Sullivan and Worcester (Har-Even & Co.) |
| Sullivan & Worcester Tel-Aviv (Har-Even & Co.) |

---

## Exhibit 23.1

**Exhibit 23.1**

<u>Consent of Independent Registered Public Accounting Firm</u>

Inspira Technologies Oxy B.H.N. Ltd.

2 Ha-Tidhar St.

Rananna 4366504, Israel

We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 6, 2025, relating to the financial statements of Inspira Technologies OXY B.H.N. Ltd. appearing in the Company's Annual Report on Form 20-F for the year ended December 31, 2024. Our report contains an explanatory paragraph regarding the Company's ability to continue as a going concern.

---

| |
|:---|
| /s/ Ziv Haft |
| Certified Public Accountants (Isr.) |
| BDO Member Firm |

---

Tel Aviv, Israel

January 6, 2026

## Ex-Filing

?xml version='1.0' encoding='ASCII'? Filing Fee Exhibit

**Ex-Filing Fees**

**CALCULATION OF FILING FEE TABLES**

**S-8**

**Inspira Technologies OXY B.H.N. Ltd**

**Table 1: Newly Registered Securities**

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| **Security Type** | **Security Class Title** | **Notes** | **Fee Calculation<br> Rule** | **Amount Registered** | **Proposed Maximum Offering<br> Price Per Unit** | **Maximum Aggregate Offering Price** | **Fee Rate** | **Amount of Registration Fee** |
| Equity | Ordinary Shares, no par value per share | (1) | Other | 512498 | $0.94 | $481748.12 | 0.0001381 | $66.53 |
| Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | $481748.12 |  | 66.53 |
| Total Fee Offsets: | Total Fee Offsets: | Total Fee Offsets: | Total Fee Offsets: | Total Fee Offsets: | Total Fee Offsets: |  |  | 0.00 |
| Net Fee Due: | Net Fee Due: | Net Fee Due: | Net Fee Due: | Net Fee Due: | Net Fee Due: |  |  | $66.53 |

---

**__________________________________________ Offering Note(s)**

&nbsp;&nbsp;&nbsp;&nbsp;(1) Pursuant to Rule 416(a) under the Securities Act of 1933, as amended, or the Securities Act, this Registration Statement also covers an indeterminate number of additional securities which may be offered and issued to prevent dilution resulting from stock splits, stock dividends, recapitalizations or similar transactions. Represents ordinary shares, no par value, of Inspira Technologies Oxy B.H.N. Ltd., or Ordinary Shares and the Registrant, respectively, reserved for issuance in connection with securities awards that may be granted under the Company's Amended and Restated 2019 Equity Incentive Plan, or the Amended and Restated 2019 Plan, to which this Registration Statement relates. The fee is based on the number of Ordinary Shares which may be issued in connection with securities awards that may be granted under the Amended and Restated 2019 Plan that this Registration Statement on Form S-8 relates to and is estimated in accordance with Rule 457(c) and (h) under the Securities Act solely for the purpose of calculating the registration fee based upon the average of the high and low sales price of the Registrant's Ordinary Shares as reported on the Nasdaq Capital Market on January 2, 2026.