# EDGAR Filing Document

**Accession Number:** 0001768946
**File Stem:** 0001104659-23-008366
**Filing Date:** 2023-1
**Character Count:** 15514
**Document Hash:** f0c4926e1f7cc1d5cb47ddf39061e92d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-23-008366.hdr.sgml**: 20230131

**ACCESSION NUMBER**: 0001104659-23-008366

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 3

**CONFORMED PERIOD OF REPORT**: 20230131

**FILED AS OF DATE**: 20230131

**DATE AS OF CHANGE**: 20230131

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Biophytis SA
- **CENTRAL INDEX KEY:** 0001768946
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** I0

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38974
- **FILM NUMBER:** 23570920

**BUSINESS ADDRESS:**
- **STREET 1:** SORBONNE UNIVERSITY, BC 9
- **STREET 2:** BATIMENT A 4EME ETAGE, 4 PLACE JUSSIEU
- **CITY:** PARIS
- **STATE:** I0
- **ZIP:** 75001
- **BUSINESS PHONE:** 33 1 44 37 23 00

**MAIL ADDRESS:**
- **STREET 1:** SORBONNE UNIVERSITY, BC 9
- **STREET 2:** BATIMENT A 4EME ETAGE, 4 PLACE JUSSIEU
- **CITY:** PARIS
- **STATE:** I0
- **ZIP:** 75001

**UNITED STATES SECURITIES**

**AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 6-K**

**REPORT OF FOREIGN PRIVATE ISSUER**

**PURSUANT TO RULE 13a-16 OR 15d-16**

**UNDER THE SECURITIES EXCHANGE ACT OF 1934**

**Date of report: January 31, 2023**

**Commission File Number: 001-38974**

**BIOPHYTIS S.A.**

**(Translation of registrant's name into English)**

**Stanislas Veillet<br> Biophytis S.A.**

**Sorbonne University—BC 9, Bâtiment A 4ème étage**

**4 place Jussieu**

**75005 Paris, France**

**+33 1 44 27 23 00**

**(Address of principal executive office)**

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

⌧ Form 20-F ◻ Form 40-F

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ◻

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ◻

On January 31, 2023, Biophytis S.A. issued a press release announcing the publication of its interim financial report for the first half of 2022 and its adjusted financial results as of 31 December 2021. A copy of the press release is attached as Exhibit 99.1 to this Form 6-K.

**EXHIBIT LIST**

---

| | |
|:---|:---|
| **Exhibit** | **Description** |
| [<u>99.1</u>](tm234994d1_ex99-1.htm) | [<u>Press Release dated January 31, 2023.</u>](tm234994d1_ex99-1.htm) |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  | **BIOPHYTIS S.A.** | **BIOPHYTIS S.A.** |
| Date: January 31, 2023 | By: | /s/ Stanislas Veillet |
|  |  | Name: Stanislas Veillet |
|  |  | Title: Chairman and Chief Executive Officer |

---

## Exhibit 99.1

**Exhibit 99.1**

![](tm234994d1_ex99-1img001.gif)

**Press release**

**Biophytis publishes** 

**its financial results for the first half of 2022**

&nbsp;&nbsp;&nbsp;&nbsp;· **Cash and cash equivalents: €19.7m as of June 30, 2022** 

&nbsp;&nbsp;&nbsp;&nbsp;· **Net loss down 8% at €12.4m for first half of 2022** 

**Publication of restated financial results as of December 31<sup>st</sup>, 2021**

**Paris (France), Cambridge (Massachusetts, USA), January 31st 2023, 08am CET** – Biophytis SA (NasdaqCM: BPTS, Euronext Growth Paris: ALBPS), **("Biophytis" or the "Company"),** a clinical-stage biotechnology company focused on the development of therapeutics that slow the degenerative processes associated with aging, including severe respiratory failure in patients suffering from COVID-19, today publishes its interim financial report for the first half of 2022 and its adjusted financial results as of 31 December 2021.

**<u>1/ Financial results for the first half of 2022</u>**

· Cash and cash equivalents. Cash and cash equivalents and short-term deposits included in other current financial assets as of June 30, 2022, were €19.7 million, a decrease of €4.2 million compared to €23.9 million as of December 31, 2021.

· Research and Development Expenses. Net research and development expenses were €6.9 million for the first half of 2022, a decrease of €0.7 million, compared to €7.6 million in the first half of 2021. This change is mainly due to the end of the SARA-INT clinical trial operational phase in 2021.

· General and Administrative Expenses. General and administrative expenses were €5.1 million for the first half of 2021 compared to €2.9 million for the first half of 2021, an increase of €2.1 million, primarily related to new expenses following our listing on Nasdaq in February 2021, which resulted in a significant increase in legal and accounting fees.

· Financial loss. Our financial loss has decreased significantly from €2.7 million in the first half of 2021 to €0.5 million in the first half of 2022. The first quarter of 2021 was strongly impacted by the dispute with Negma Group Ltd.

· Net Loss. The net loss decreased by 8% to €12.4 million in the first half 2022 from €13.2 million in the first half of 2021. The net loss per share (based on the weighted average number of shares outstanding during the period) was €0.08 for the first half of 2022 compared to €0.12 for the first half of 2021.

![](tm234994d1_ex99-1img001.gif)

**Press release**

Cash and cash equivalents on the 30<sup>th</sup> of June 2022 amounted to €19.7 million. The Company considers that this amount, together with the credit lines in place, is sufficient to cover the Company's cash requirements for the next 12 months.

**<u>Consolidated financial statements</u>**

---

| | | |
|:---|:---|:---|
| **(amounts in thousands of euros)** | **12/31/2021** | **06/30/2022** |
| **TOTAL NON CURRENT ASSETS** | **3506** | **3552** |
| **TOTAL CURRENT ASSETS** | **31366** | **30334** |
| &nbsp;&nbsp;&nbsp;Other debts | 6536 | 10181 |
| &nbsp;&nbsp;&nbsp;Current financial assets | 904 | 407 |
| &nbsp;&nbsp;&nbsp;Cash and cash equivalents | 23926 | 19745 |
| **TOTAL ASSETS** | **34875** | **33886** |
| **SHAREHOLDER'S EQUITY** | **5803** | **2961** |
| &nbsp;&nbsp;&nbsp;**Shareholders' equity - group share** | **5835** | **2993** |
| **TOTAL NON-CURRENT LIABILITIES** | **6259** | **5210** |
| **TOTAL CURRENT LIABILITIES** | **22809** | **25716** |
| **TOTAL LIABILITIES** | **34872** | **33886** |

---

**<u>Consolidated income statement</u>**

---

| | | |
|:---|:---|:---|
| <br>**(amounts in thousands of euros)** | **06/30/2021**<br>**6 months** | **06/30/2022**<br>**6 months** |
| Revenues | - | - |
| Cost of sales | - | - |
| **Gross margin** | **-** | **-** |
| Research and development costs, net | (7594) | (6867) |
| General and administrative costs | (2919) | (5053) |
| **Operating profit** | **(10513)** | **(11920)** |
| Financial result | (2732) | (478) |
| Tax income (expense) | - | - |
| **Net result (loss)** | **(13245)** | **(12398)** |
| Actuarial gain and losses | 7 | 40 |
| Exchange rate differences | 3 | 46 |
| **Other items of net income (net of tax)** | **10** | **86** |
| **Net income (loss)** | **(13235)** | **(12312)** |
| **Net income (loss) – Group share** | **(13235)** | **(12312)** |

---

![](tm234994d1_ex99-1img001.gif)

**Press release**

**<u>Cash flow statement</u>**

---

| | | |
|:---|:---|:---|
| <br>**(amounts in thousands of euros)** | **06/30/2021**<br>**6 months** | **06/30/2022**<br>**6 months** |
| Change in cash flow: |  |  |
| &nbsp;&nbsp;&nbsp;Cash flow from operating activities | (13492) | (10261) |
| &nbsp;&nbsp;&nbsp;Cash flow from investing activities | 12474 | 333 |
| &nbsp;&nbsp;&nbsp;Cash flow from financing activities | 18156 | 5689 |
| Impact of changes in foreign exchange rates | 2 | 58 |
| **Increase (Decrease) in cash** | **17140** | **(4181)** |

---

**2/ Preliminary remarks**

In application of IAS 8, and as announced in the October 31<sup>st</sup>, 2022 press release, the Company has decided, following the review and discussions with its Statutory Auditors, to correct the financial statements as of December 31<sup>st</sup>, 2021 to reflect the correct interpretation of the financing agreement signed with Kréos on 19 November 2021.

These technical corrections are related to an inappropriate interpretation of the various instruments of this financing, which includes straight bonds, convertible bonds, warrants and conversion options.

These technical corrections have no impact on the Company's cash position and a very marginal impact on net result (0.3%). The impact is mainly on the balance sheet (3.8%).

Full details of these corrections are described in the financial report and the 20F/A for the relevant period, available today on the company's website, and filed to the AMF and the SEC.

![](tm234994d1_ex99-1img001.gif)

**Press release**

**3/ Results of the restatement of the accounts as of December 31<sup>st</sup> 2021 is summarized below:** 

<u>Impact on the Company's consolidated financial statements</u> 

---

| | | | |
|:---|:---|:---|:---|
| | **DECEMBER 31, 2021** | **DECEMBER 31, 2021** | **DECEMBER 31, 2021** |
| <br>**(amounts in thousands of euros)** | **Previously<br> published** | **Restatements** | **Restated** |
| **ASSETS** |  |  |  |
| Patents and software | 2757 |  | 2757 |
| Tangible fixed assets | 563 |  | 563 |
| Cash and cash equivalents | 1251 | (1065) | 186 |
| **Total non-current assets** | **4571** | **(1065)** | **3506** |
| Other debts | 6536 |  | 6536 |
| Current financial assets | 1229 | (325) | 904 |
| Cash and cash equivalents | 23926 |  | 23926 |
| **Total current assets** | **31691** | **(325)** | **31366** |
| **TOTAL ASSETS** | **36262** | **(1390)** | **34872** |
| **LIABILITIES** |  |  |  |
| **Shareholder's equity** |  |  |  |
| Equity | 27191 |  | 27191 |
| Additional paid-in capital | 27781 |  | 27781 |
| Treasury shares | (51) |  | (51) |
| Exchange rate differences | (73) |  | (73) |
| Reserves - attributable to Biophytis shareholders | (17865) | 15 | (17850) |
| Result - attributable to Biophytis shareholders | (31246) | 83 | (31163) |
| **Equity - attributable to Biophytis shareholders** | **5737** | **98** | **5835** |
| Non-controlling interests | (32) | - | (32) |
| **Total equity** | **5705** | 98 | **5803** |
| Commitments to staff | 205 |  | 205 |
| Non-current financial debts | 6293 | (775) | 5518 |
| Non-current derivative liabilities | 916 | (380) | 536 |
| **Total non-current liabilities** | **7414** | **(1 155)** | **6259** |
| Current financial liabilities | 12370 | (333) | 12037 |
| Provisions |  |  |  |
| Trade creditors and related accounts | 7606 |  | 7606 |
| Tax and social security liabilities | 1998 |  | 1998 |
| Current derivative liabilities | 788 |  | 788 |
| Other creditors and miscellaneous liabilities | 381 | - | 381 |
| **Total current liabilities** | **23143** | **(333)** | **22810** |
| **TOTAL LIABILITIES** | **36262** | **(1390)** | **34872** |

---

![](tm234994d1_ex99-1img001.gif)

**Press release**

<u>Impact on the Company's consolidated income statement</u>

---

| | | | |
|:---|:---|:---|:---|
| | **FOR THE YEAR ENDED <br> DECEMBER 31, 2021** | **FOR THE YEAR ENDED <br> DECEMBER 31, 2021** | **FOR THE YEAR ENDED <br> DECEMBER 31, 2021** |
| <br>**(amounts in thousands of euros)** | **Previously Published** | **Restatements** | **Restated** |
| **Gross margin** | **-** | **-** | **-** |
| Research and development costs, net | (19665) |  | (19665) |
| General and administrative costs | (7150) | - | (7150) |
| **Operating profit** | **(26 815)** | **-** | **(26815)** |
| Financial costs | (2581) | **64** | (2517) |
| Financial proceeds | 24 | **-** | 24 |
| Change in fair value of convertible bonds | (1875) | **19** | (1856) |
| **Financial results** | **(4432)** | **83** | **(4349)** |
| **Result before tax** | **(31247)** | **83** | **(31182)** |
| Tax income (expense) | - | - | - |
| **Net result (loss)** | **(31247)** | **83** | **(31164)** |
| to Biophytis' shareholders | (31247) | **83** | (31164) |
| Non-controlling interests | (1) |  | (1) |
| Weighted average number of outstanding shares | 118282679 | - | 118282679 |
| **Earning per share (€/share)** | **(0.26)** | **-** | **(0.26)** |
| **Diluted earning per share (€/share)** | **(0.26)** | **-** | **(0.26)** |

---

**\*\*\***

![](tm234994d1_ex99-1img001.gif)

**Press release**

**About BIOPHYTIS**

Biophytis SA is a clinical-stage biotechnology company specialized in the development of therapeutics that are aimed at slowing the degenerative processes associated with aging and improving functional outcomes for patients suffering from age-related diseases, including severe respiratory failure in patients suffering from COVID-19. Sarconeos (BIO101), our leading drug candidate, is a small molecule, administered orally, being developed as a treatment for sarcopenia in a Phase 2 clinical trial in the United States and Europe (SARA-INT). It has also been studied in a clinical two-part Phase 2-3 study (COVA) for the treatment of severe respiratory manifestations of COVID-19 in Europe, Latin America, and the US. A pediatric formulation of Sarconeos (BIO101) is being developed for the treatment of Duchenne Muscular Dystrophy (DMD). The Company is based in Paris, France, and Cambridge, Massachusetts. The Company's ordinary shares are listed on Euronext Growth (Ticker: ALBPS -ISIN: FR0012816825) and ADSs (American Depositary Shares) are listed on Nasdaq Capital Market (Ticker BPTS – ISIN: US09076G1040). For more information visit www.biophytis.com

**Disclaimer**

This press release contains forward-looking statements. Forward-looking statements include all statements that are not historical facts. In some cases, you can identify these forward-looking statements by the use of words such as "outlook," "believes," "expects," "potential," "continues," "may," "will," "should," "could," "seeks," "predicts," "intends," "trends," "plans," "estimates," "anticipates" or the negative version of these words or other comparable words. Such forward-looking statements are based on assumptions that Biophytis considers to be reasonable. However, there can be no assurance that the statements contained in such forward-looking statements will be verified, which are subject to various risks and uncertainties. The forward-looking statements contained in this press release are also subject to risks not yet known to Biophytis or not currently considered material by Biophytis. Accordingly, there are or will be important factors that could cause actual outcomes or results to differ materially from those indicated in these statements. Please also refer to the "Risk and uncertainties the Company is to face" section from the Company's 2021 Half Year Financial Report available on BIOPHYTIS website (www.biophytis.com) and as exposed in the "Risk Factors" section of form 20-F as well as other forms filed with the SEC (Securities and Exchange Commission, USA). We undertake no obligation to publicly update or review any forward-looking statement, whether as a result of new information, future developments or otherwise, except as required by law.

**Biophytis Contact for Investor Relations**

Philippe Rousseau CFO

<u>Investors@biophytis.com</u>

**Media Contacts**

Antoine Denry: <u>antoine.denry@taddeo.fr</u> +33 6 18 07 83 27<br> Agathe Boggio: <u>agathe.boggio@taddeo.fr</u> +33 7 62 77 69 42