# EDGAR Filing Document

**Accession Number:** 0001782107
**File Stem:** 0001213900-26-053206
**Filing Date:** 2026-5
**Character Count:** 1993
**Document Hash:** 099fe3f297d477f933a60ecaa3c87b87
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-26-053206.hdr.sgml**: 20260608

**ACCESSION NUMBER**: 0001213900-26-053206

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20260507

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Onconetix, Inc.
- **CENTRAL INDEX KEY:** 0001782107
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 201 E. FIFTH STREET
- **STREET 2:** SUITE 1900
- **CITY:** CINCINNATI
- **STATE:** OH
- **ZIP:** 45202
- **BUSINESS PHONE:** 513-620-4101

**MAIL ADDRESS:**
- **STREET 1:** 201 E. FIFTH STREET
- **STREET 2:** SUITE 1900
- **CITY:** CINCINNATI
- **STATE:** OH
- **ZIP:** 45202

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Blue Water Biotech, Inc.
- **DATE OF NAME CHANGE:** 20230424

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Blue Water Vaccines Inc.
- **DATE OF NAME CHANGE:** 20190710

**Onconetix, Inc.**

**201 E. Fifth Street, Suite 1900**

**Cincinnati, OH 45202**

**<u>VIA EDGAR</u>**

May 7, 2026

U.S. Securities and Exchange Commission

Office of Life Sciences

Washington, D.C. 20549

Attn: Tim Buchmiller

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| | |
|:---|:---|
| Re: | **Onconetix, Inc.** |
|  | **Registration Statement on Form S-1** |
|  | **Filed April 28, 2026** |
|  | **File No. 333-295376** |

---

Ladies and Gentleman,

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Onconetix, Inc. hereby requests acceleration of effectiveness of the above referenced Registration Statement so that it will become effective at 5:00 p.m. EST on Thursday, May 7, 2026, or as soon as thereafter practicable.

---

| |
|:---|
| Very truly yours, |
| /s/ David Allan White |
| By: David Allan White |
| Title: Chief Executive Officer |

---

cc: Ellenoff Grossman & Schole LLP