# EDGAR Filing Document

**Accession Number:** 0001583977
**File Stem:** 0000929638-23-000553
**Filing Date:** 2023-2
**Character Count:** 32556
**Document Hash:** a01dbaa5c53864feacc982c3bb430e9d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000929638-23-000553.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0000929638-23-000553

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230214

**DATE AS OF CHANGE**: 20230214

**GROUP MEMBERS**: BIHUA CHEN

**GROUP MEMBERS**: CORMORANT GLOBAL HEALTHCARE GP, LLC

**GROUP MEMBERS**: CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP

**GROUP MEMBERS**: CORMORANT PRIVATE HEALTHCARE FUND II, LP

**GROUP MEMBERS**: CORMORANT PRIVATE HEALTHCARE FUND III, LP

**GROUP MEMBERS**: CORMORANT PRIVATE HEALTHCARE GP II, LLC

**GROUP MEMBERS**: CORMORANT PRIVATE HEALTHCARE GP III, LP

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** VectivBio Holding AG
- **CENTRAL INDEX KEY:** 0001836379
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** V8
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-92481
- **FILM NUMBER:** 23627669

**BUSINESS ADDRESS:**
- **STREET 1:** AESCHENVORSTADT 36
- **CITY:** BASEL
- **STATE:** V8
- **ZIP:** 4051
- **BUSINESS PHONE:** 41 61 551 30 30

**MAIL ADDRESS:**
- **STREET 1:** AESCHENVORSTADT 36
- **CITY:** BASEL
- **STATE:** V8
- **ZIP:** 4051
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Cormorant Asset Management, LP
- **CENTRAL INDEX KEY:** 0001583977
- **IRS NUMBER:** 462108927
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** 200 CLARENDON STREET
- **STREET 2:** 52ND FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116
- **BUSINESS PHONE:** 857-702-0388

**MAIL ADDRESS:**
- **STREET 1:** 200 CLARENDON STREET
- **STREET 2:** 52ND FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Cormorant Asset Management, LLC
- **DATE OF NAME CHANGE:** 20130807

---

| |
|:---|
| **UNITED STATES**<br> **SECURITIES AND EXCHANGE COMMISSION**<br> **Washington, D.C. 20549**<br> **<br>** <br>|
| **SCHEDULE 13G**<br>|
| **Under the Securities Exchange Act of 1934**<br>|
| **(Amendment No. 1)**\*<br>|
| **VectivBio Holding AG** |
| (Name of Issuer)<br>|
| **Ordinary Shares** |
| (Title of Class of Securities) |

---

---

| |
|:---|
| **H9060V101** |
| (CUSIP Number) |

---

---

| |
|:---|
| **December 31, 2022** |
| (Date of Event which Requires Filing of this Statement) |

---

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

[ ] Rule 13d-1(b)

[x] Rule 13d-1(c)

[ ] Rule 13d-1(d)

___________________________________

\* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, *see* the Notes).

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Global Healthcare Master Fund, LP | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Global Healthcare Master Fund, LP |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Cayman Islands | Citizenship or Place of Organization.<br>Cayman Islands |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>1,515,087 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>1,515,087 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1,515,087 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1,515,087 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>2.42%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>2.42%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>PN (Partnership) | Type of Reporting Person (See Instructions)<br>PN (Partnership) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Global Healthcare GP, LLC | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Global Healthcare GP, LLC |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Delaware | Citizenship or Place of Organization.<br>Delaware |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>1,515,087 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>1,515,087 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1,515,087 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1,515,087 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>2.42%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>2.42%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>OO (Limited Liability Company) | Type of Reporting Person (See Instructions)<br>OO (Limited Liability Company) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare Fund II, LP | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare Fund II, LP |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Delaware | Citizenship or Place of Organization.<br>Delaware |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>453,963 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>453,963 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>453,963 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>453,963 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>0.72%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>0.72%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>PN (Partnership) | Type of Reporting Person (See Instructions)<br>PN (Partnership) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare GP II, LLC | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare GP II, LLC |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Delaware | Citizenship or Place of Organization.<br>Delaware |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>453,963 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>453,963 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>453,963 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>453,963 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>0.72%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>0.72%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>OO (Limited Liability Company) | Type of Reporting Person (See Instructions)<br>OO (Limited Liability Company) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare Fund III, LP | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare Fund III, LP |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Delaware | Citizenship or Place of Organization.<br>Delaware |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>567,567 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>567,567 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>567,567 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>567,567 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>0.90%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>0.90%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>PN (Partnership) | Type of Reporting Person (See Instructions)<br>PN (Partnership) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare GP III, LLC | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Private Healthcare GP III, LLC |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Delaware | Citizenship or Place of Organization.<br>Delaware |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>567,567 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>567,567 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>567,567 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>567,567 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>0.90%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>0.90%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>OO (Limited Liability Company) | Type of Reporting Person (See Instructions)<br>OO (Limited Liability Company) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Asset Management, LP | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Cormorant Asset Management, LP |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>Delaware | Citizenship or Place of Organization.<br>Delaware |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>2,536,617 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>2,536,617 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2,536,617 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2,536,617 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>4.04% <br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>4.04% <br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>PN (Partnership) | Type of Reporting Person (See Instructions)<br>PN (Partnership) |

---

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CUSIP NO. H9060V101

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| | | |
|:---|:---|:---|
| 1 | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Bihua Chen | Names of Reporting Persons.<br> I.R.S. Identification Nos. of above persons (entities only)<br>Bihua Chen |
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) [ ] | (a) [ ] |
|  | (b) [x] | (b) [x] |
| 3 | SEC Use Only | SEC Use Only |
| 4 | Citizenship or Place of Organization.<br>United States | Citizenship or Place of Organization.<br>United States |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 5 Sole Voting Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 6 Shared Voting Power<br>2,536,617 shares<br>Refer to Item 4 below. |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7 Sole Dispositive Power<br>0 shares |
| Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | Number<br> of Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;&nbsp;&nbsp; 8 Shared Dispositive Power<br>2,536,617 shares<br>Refer to Item 4 below. |
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2,536,617 shares<br>Refer to Item 4 below. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2,536,617 shares<br>Refer to Item 4 below. |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)<br> &nbsp;&nbsp;&nbsp;&nbsp;[ ] N/A |
| 11 | Percent of Class Represented by Amount in Row (9)\*<br>4.04%<br>Refer to Item 4 below. | Percent of Class Represented by Amount in Row (9)\*<br>4.04%<br>Refer to Item 4 below. |
| 12 | Type of Reporting Person (See Instructions)<br>IN (Individual) | Type of Reporting Person (See Instructions)<br>IN (Individual) |

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CUSIP NO. H9060V101

#### <br>

#### Item 1.

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| | |
|:---|:---|
| (a) | Name of Issuer<br>|
|  | VectivBio Holding AG<br>|
| (b) | Address of Issuer's Principal Executive Offices |
|  | <br> Aeschenvorstadt 36, 4051 Basel, Switzerland |

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#### Item 2.

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| | |
|:---|:---|
| (a) | Name of Person Filing |
|  | <br> Cormorant Global Healthcare Master Fund, LP<br> Cormorant Global Healthcare GP, LLC<br> Cormorant Private Healthcare Fund II, LP<br> Cormorant Private Healthcare GP II, LLC<br> Cormorant Private Healthcare Fund III, LP<br> Cormorant Private Healthcare GP III, LLC<br> Cormorant Asset Management, LP<br> Bihua Chen<br>|
| (b) | Address of Principal Business Office or, if none, Residence |
|  | 200 Clarendon Street, 52nd Floor<br> Boston, MA 02116<br>|
| (c) | Citizenship |
|  | <br> Cormorant Global Healthcare Master Fund, LP - Cayman Islands<br> Cormorant Global Healthcare GP, LLC - Delaware<br> Cormorant Private Healthcare Fund II, LP - Delaware<br> Cormorant Private Healthcare GP II, LLC - Delaware<br> Cormorant Private Healthcare Fund III, LP - Delaware<br> Cormorant Private Healthcare GP III, LLC - Delaware<br> Cormorant Asset Management, LP - Delaware<br> Bihua Chen - United States<br>|
| (d) | Title of Class of Securities |
|  | Ordinary Shares<br>|
| (e) | CUSIP Number |
|  | H9060V101 |

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CUSIP NO. H9060V101

**Item 3.** **If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:**<br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) [ ] Insurance Company as defined in Section 3(a)(19) of the Act

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) [ ] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e) [ ] An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(f) [ ] An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(g) [ ] A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(j) [ ] A non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(k) [ ] Group, in accordance with §240.13d-1(b)(1)(ii)(K).

**Item 4.** **Ownership\*\*\***<br>

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

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| | |
|:---|:---|
| (a) | Amount Beneficially Owned\*\*\* |
|  | <br> The information set forth in Rows 5 through 11 on the cover page for each Reporting Person is hereby incorporated by reference into this Item 4(a) for each such Reporting Person. |

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CUSIP NO. H9060V101

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| | |
|:---|:---|
| (b) | Percent of Class |
|  | <br> The information set forth in Rows 5 through 11 on the cover page for each Reporting Person is hereby incorporated by reference into this Item 4(b) for each such Reporting Person. |

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| | | |
|:---|:---|:---|
| (c) | Number of shares as to which such person has: | Number of shares as to which such person has: |
|  | (i) | sole power to vote or to direct the vote |
|  | (ii) | shared power to vote or to direct the vote |
|  | (iii) | sole power to dispose or to direct the disposition of |

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CUSIP NO. H9060V101

(iv) shared power to dispose or to direct the disposition of <br>The information set forth in Rows 5 through 11 on the cover page for each Reporting Person is hereby incorporated by reference into this Item 4(c) for each such Reporting Person.

\*\*\* Shares reported herein for Cormorant Asset Management, LP represent shares which are beneficially owned by Cormorant Global Healthcare Master Fund, LP (the "Master Fund"), Cormorant Private Healthcare Fund II, LP ("Fund II") and Cormorant Private Healthcare Fund III, LP ("Fund III"), as reported herein. Cormorant Global Healthcare GP, LLC, Cormorant Private Healthcare GP II, LLC and Cormorant Private Healthcare GP III, LLC serve as the general partners of the Master Fund, Fund II and Fund III, respectively. Cormorant Asset Management, LP serves as the investment manager to the Master Fund, Fund II and Fund III. Bihua Chen serves as the managing member of Cormorant Global Healthcare GP, LLC, Cormorant Private Healthcare GP II, LLC, Cormorant Private Healthcare GP III, LLC and the general partner of Cormorant Asset Management, LP. Each of the Reporting Persons disclaims beneficial ownership of the shares reported herein except to the extent of its or his pecuniary interest therein.

The percentages reported herein with respect to the Reporting Persons' holdings are calculated based upon a statement in an amendment to the Issuer's Registration Statement on Form F-3 filed with the Securities and Exchange Commission on November 10, 2022, that there were 62,732,542 ordinary shares outstanding as of November 10, 2022.

**Item 5.** **Ownership of Five Percent or Less of a Class**<br>

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [X].

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CUSIP NO. H9060V101

**Item 6.** **Ownership of More than Five Percent on Behalf of Another Person**<br>

Not applicable.

**Item 7.** **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company**<br>

Not applicable.

**Item 8.** **Identification and Classification of Members of the Group**<br>

Not applicable.

**Item 9.** **Notice of Dissolution of Group**<br>

Not applicable.

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| | |
|:---|:---|
| **Item 10.** | **Certification** |

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By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

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| | |
|:---|:---|
| **Exhibits**  | **Exhibit** |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;99.1 Joint Filing Agreement by and among the Reporting Persons, incorporated by reference to Exhibit 99.1 to the Schedule 13G filed by the Reporting Persons with the
 Securities and Exchange Commission on June 17, 2022.

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**CUSIP NO. H9060V101**

#### <br>

#### SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this Statement is true, complete and correct.

February 14, 2023

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| |
|:---|
| CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP |
| By: Cormorant Global Healthcare GP, LLC |
| its General Partner |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| CORMORANT GLOBAL HEALTHCARE GP, LLC |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| CORMORANT PRIVATE HEALTHCARE FUND II, LP |
| By: Cormorant Global Healthcare GP II, LLC |
| its General Partner |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| CORMORANT PRIVATE HEALTHCARE GP II, LLC |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| CORMORANT PRIVATE HEALTHCARE FUND III, LP |
| By: Cormorant Global Healthcare GP III, LLC |
| its General Partner |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| CORMORANT PRIVATE HEALTHCARE GP III, LLC |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| CORMORANT ASSET MANAGEMENT, LP |
| By: Cormorant Asset Management GP, LLC |
| its General Partner |
| By: <u>/s/ Bihua Chen</u> |
| Bihua Chen, Managing Member |
| <u>/s/ Bihua Chen</u> |
| Bihua Chen |

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