# EDGAR Filing Document

**Accession Number:** 0001734005
**File Stem:** 0001213900-25-116477
**Filing Date:** 2025-12
**Character Count:** 2347
**Document Hash:** f92065b81b006a975b8c3a49b44ea817
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-25-116477.hdr.sgml**: 20260417

**ACCESSION NUMBER**: 0001213900-25-116477

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20251201

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Aptorum Group Ltd
- **CENTRAL INDEX KEY:** 0001734005
- **STANDARD INDUSTRIAL CLASSIFICATION:** MEASURING & CONTROLLING DEVICES, NEC [3829]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 17 HANOVER SQUARE
- **CITY:** LONDON
- **STATE:** X0
- **ZIP:** W1S 1BN
- **BUSINESS PHONE:** 852 3953 7700

**MAIL ADDRESS:**
- **STREET 1:** 17 HANOVER SQUARE
- **CITY:** LONDON
- **STATE:** X0
- **ZIP:** W1S 1BN

**APTORUM GROUP LIMITED**

17 Hanover Square

London W1S 1BN, United Kingdom

December 1, 2025

**<u>VIA EDGAR</u>**

U.S. Securities and Exchange Commission

Division of Corporation Finance

Office of Life Science

100 F Street, N.E.

Mail Stop 4631

Washington, DC 20549

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| | |
|:---|:---|
| **Re:** | **Aptorum Group Ltd** |
|  | **Registration Statement on Form F-1** |
|  | **Filed November 17, 2025** |
|  | **File No. 333-291593** |

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Dear Sir and Madam:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Aptorum Group Limited hereby respectfully requests acceleration of effectiveness of the above referenced Registration Statement so that it will become effective at 2:00 p.m. Eastern Time on Wednesday, December 3, 2025, or as soon as thereafter practicable.

The Company understands that the Commission will consider this request for acceleration of the effective date of the Registration Statement as a confirmation of the fact that the Company is aware of its responsibilities under the Securities Act as they relate to the offering of the securities specified in the Registration Statement.

We thank the Staff for your review of the foregoing. If you have any further concerns, we ask that you forward them by electronic mail to our counsel, Louis Taubman at <u>ltaubman@htflawyers.com</u> or by telephone at (917) 512-0827.

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| |
|:---|
| /s/ Ian Huen |
| Ian Huen<br> CEO |

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cc: Louis Taubman <br> Hunter Taubman Fischer& Li LLC