# EDGAR Filing Document

**Accession Number:** 0001357874
**File Stem:** 0000059478-23-000022
**Filing Date:** 2023-1
**Character Count:** 8665
**Document Hash:** af814a5a38ec41d98f5bb72d4ab27a67
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000059478-23-000022.hdr.sgml**: 20230127

**ACCESSION NUMBER**: 0000059478-23-000022

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230127

**DATE AS OF CHANGE**: 20230127

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PRECISION BIOSCIENCES INC
- **CENTRAL INDEX KEY:** 0001357874
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-90975
- **FILM NUMBER:** 23564015

**BUSINESS ADDRESS:**
- **STREET 1:** 302 EAST PETTIGREW STREET
- **STREET 2:** SUITE A-100
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27701
- **BUSINESS PHONE:** 919-314-5512

**MAIL ADDRESS:**
- **STREET 1:** 302 EAST PETTIGREW STREET
- **STREET 2:** SUITE A-100
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27701
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ELI LILLY & Co
- **CENTRAL INDEX KEY:** 0000059478
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 350470950
- **STATE OF INCORPORATION:** IN
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** LILLY CORPORATE CTR
- **STREET 2:** DROP CODE 1094
- **CITY:** INDIANAPOLIS
- **STATE:** IN
- **ZIP:** 46285
- **BUSINESS PHONE:** 3172762000

**MAIL ADDRESS:**
- **STREET 1:** LILLY CORPORATE CENTER
- **STREET 2:** DROP CODE 1094
- **CITY:** INDIANAPOLIS
- **STATE:** IN
- **ZIP:** 46285

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** LILLY ELI & CO
- **DATE OF NAME CHANGE:** 19941024

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**SCHEDULE 13G/A**

**Under the Securities Exchange Act of 1934**

**(Amendment No: 1)\***

**Precision BioSciences, Inc.**

**(Name of Issuer)**

**Common Stock, par value $0.000005 per share**

**(Title of Class of Securities)**

**74019P108** 

**(CUSIP Number)**

**December 31, 2022**

**(Date of Event which Requires Filing of this Statement)**

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

🗷 Rule 13d-1(c)

☐ Rule 13d-1(d)

\*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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CUSIP No. 74019P108 <br>

&nbsp;&nbsp;&nbsp;&nbsp;1. Names of Reporting Persons Eli Lilly and Company 35-0470950

&nbsp;&nbsp;&nbsp;&nbsp;2. Check the Appropriate Box if a Member of a Group (See Instructions) &nbsp;&nbsp;&nbsp;&nbsp; (a) ☐ &nbsp;&nbsp;&nbsp;&nbsp; (b) ☐ <br>

&nbsp;&nbsp;&nbsp;&nbsp;3. SEC Use Only

&nbsp;&nbsp;&nbsp;&nbsp;4. Citizenship or Place of Organization <br> Indiana

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| | | |
|:---|:---|:---|
| NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>WITH | &nbsp;&nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power<br>3,762,190 |
| NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>WITH | &nbsp;&nbsp;&nbsp;6. | &nbsp;&nbsp;Shared Voting Power<br>0 |
| NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>WITH | &nbsp;&nbsp;&nbsp;7. | &nbsp;&nbsp;Sole Dispositive Power<br>3,762,190 |
| NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>WITH | &nbsp;&nbsp;&nbsp;8. | &nbsp;&nbsp;Shared Dispositive Power<br>0 |

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&nbsp;&nbsp;&nbsp;&nbsp;9. Aggregate Amount Beneficially Owned by Each Reporting Person <br> 3,762,190

&nbsp;&nbsp;&nbsp;&nbsp;10. Check Box if the Aggregate Amount in Row 9 Excludes Certain Shares (See Instructions) ☐ <br>

&nbsp;&nbsp;&nbsp;&nbsp;11. Percent of Class Represented by Amount in Row (9) <br> 3.4% <sup>(1)</sup>

&nbsp;&nbsp;&nbsp;&nbsp;12. Type of Reporting Person (See Instructions) <br> CO

<sup>(1)</sup> The percentage is calculated based upon 110,958,955 outstanding shares of Common Stock of the Issuer as of November 3, 2022, as reported on on Form 10-Q, filed on November 8, 2022.

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| | |
|:---|:---|
| **Item 1.** | **Name of Issuer** |

---

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| | |
|:---|:---|
| (a) | &nbsp;&nbsp;&nbsp;&nbsp;Name of Issuer: |
| | &nbsp;&nbsp;&nbsp;&nbsp;Precision Biosciences, Inc. |
| (b) | &nbsp;&nbsp;&nbsp;&nbsp;Address of Issuer's Principal Executive Offices: |
| | &nbsp;&nbsp;&nbsp;&nbsp;302 East Pettigrew Street, Suite A-100 |
| | &nbsp;&nbsp;&nbsp;&nbsp;Durham, NC 27701 |

---

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| | |
|:---|:---|
| **Item 2.** | **Name of Person Filing** |

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(a) Name: <br> Eli Lilly and Company

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| | |
|:---|:---|
| (b) | &nbsp;&nbsp;&nbsp;&nbsp;Address of Principal Business Office: |
| | &nbsp;&nbsp;&nbsp;&nbsp;c/o Lilly Corporate Center |
| | &nbsp;&nbsp;&nbsp;&nbsp;Indianapolis, Indiana 46285 |

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(c) Citizenship: <br> Indiana corporation

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| | |
|:---|:---|
| (d) | &nbsp;&nbsp;&nbsp;&nbsp;Title of Class of Securities: |
|  | &nbsp;&nbsp;&nbsp;&nbsp;Common Stock, $0.000005 par value per share |

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(e) CUSIP Number: <br> 74019P108

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| | |
|:---|:---|
| **Item 3.** | **If this statement is filed pursuant to § 240.13d-1(b) or § 240.13d-2(b) or (c), check whether the person filing is a:** |
| | Not Applicable. |

---

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| | |
|:---|:---|
| **Item 4.** | **Ownership.** |

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All ownership information is as of December 31, 2022.

(a) Amount Beneficially Owned: See Item 9 of Cover Sheet.

(b) Percent of Class: See Item 11 of Cover Sheet.

(c) Number of shares as to which the person has:

(i) sole power to vote of to direct the vote: See Item 5 of Cover Sheet.

(ii) shared power to vote or to direct the vote: See Item 6 of Cover Sheet.

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(iii) sole power to dispose or to direct the disposition of: See Item 7 of Cover Sheet.

(iv) shared power to dispose or to direct the disposition of: See Item 8 of Cover Sheet.

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| | |
|:---|:---|
| **Item 5.** | **Ownership of Five Percent or Less of a Class** |
| | If this statement is being filed to report the fact that as of the date hereof the Reporting Person has ceased to be the beneficial owner of more than five percent of the Common Stock, check the following: ☒ |

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| | |
|:---|:---|
| **Item 6.** | **Ownership of More than Five Percent on Behalf of Another Person** |
| | Not Applicable. |

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| | |
|:---|:---|
| **Item 7.** | **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company** |
| | Not Applicable. |

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| | |
|:---|:---|
| **Item 8.** | **Identification and Classification of Member of the Group** |
| | Not Applicable. |

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| | |
|:---|:---|
| **Item 9.** | **Notice of Dissolution of Group** |
| | Not Applicable. |

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| | |
|:---|:---|
| **Item 10.** | **Certification** |

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By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

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**SIGNATURES**

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

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| | | |
|:---|:---|:---|
| Dated: January 27, 2023 | ELI LILLY AND COMPANY | ELI LILLY AND COMPANY |
|  | By: | \* |
|  |  | Authorized Signatory |

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| | |
|:---|:---|
| | /s/ |
| \*By: | Christopher Anderson |
|  | Attorney-in-Fact |

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This Schedule 13G was executed pursuant to a power of attorney previously filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of attorney was filed as Exhibit 99.3 to a filing by Eli Lilly and Company on Schedule 13G for Forma Therapeutics Holdings, Inc. on February 10, 2022.

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