# EDGAR Filing Document

**Accession Number:** 0000315700
**File Stem:** 0001752724-23-067431
**Filing Date:** 2023-3
**Character Count:** 34761
**Document Hash:** 58dae1b4c03bd94ee4017928101a3003
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-23-067431.hdr.sgml**: 20230327

**ACCESSION NUMBER**: 0001752724-23-067431

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20230131

**FILED AS OF DATE**: 20230327

**DATE AS OF CHANGE**: 20230327

**PERIOD START**: 20230731

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIDELITY ADVISOR SERIES VII
- **CENTRAL INDEX KEY:** 0000315700
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** MA
- **FISCAL YEAR END:** 0731

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-03010
- **FILM NUMBER:** 23763499

**BUSINESS ADDRESS:**
- **STREET 1:** 245 SUMMER STREET
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02210
- **BUSINESS PHONE:** 617-563-7000

**MAIL ADDRESS:**
- **STREET 1:** 245 SUMMER STREET
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02210

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** FIDELITY SECURITIES TRUST
- **DATE OF NAME CHANGE:** 19920703

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PLYMOUTH SECURITIES TRUST
- **DATE OF NAME CHANGE:** 19911118

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** READY CASH FUND
- **DATE OF NAME CHANGE:** 19880207

## Series and Classes Contracts Data

### Fidelity Advisor Biotechnology Fund (Series ID: S000005321)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000014519 | Class A      | FBTAX           |
| C000014521 | Class C      | FBTCX           |
| C000014522 | Class M      | FBTTX           |
| C000014523 | Class I      | FBTIX           |
| C000204999 | Class Z      | FIJYX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** Fidelity Advisor Series VII

- **b. Investment Company Act file number:** 811-03010

- **c. CIK number of Registrant:** 0000315700

- **d. LEI of Registrant:** PM3JTBFBEM0RCCY2GO89

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 245 Summer Street

  - **City:** Boston

  - **State:** MA

  - **Foreign country:** US

  - **Zip / Postal Code:** 02210

  - **Telephone number:** 1-800-FIDELITY

**Item A.2. Information about the Series.**

- **a. Name of Series:** Fidelity Advisor Biotechnology Fund

- **b. EDGAR series identifier (if any):** S000005321

- **c. LEI of Series:** C7UWI9NYV6ZT61IPLX72

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2023-07-31

- **b. Date as of which information is reported:** 2023-01-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $1953294938.17

**Total Liabilities:** $174354769.81

**Net Assets:** $1778940168.36

**Delayed Delivery Securities:** $8105912.01

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000204999 | 1.70%                | -0.33%               | 1.17%                |
| Class ID C000014519 | -4.18%               | -6.05%               | -4.69%               |
| Class ID C000014522 | -1.92%               | -3.84%               | -2.45%               |
| Class ID C000014521 | 0.60%                | -1.40%               | 0.07%                |
| Class ID C000014523 | 1.71%                | -0.33%               | 1.14%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-21801170.82            | $52164687.25                               |
| Month 2  | $-43409736.08            | $38274189.20                               |
| Month 3  | $28450909.64             | $-10687107.87                              |

### Schedule of Portfolio Investments

| Name                              | Title                                                     | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| TERNS PHARMACEUTICALS INC         | TERNS PHARMACEUTICALS INC                                 | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |    952048 | NS      | $8635075.36   | 0.49%             |  |  |  | No            |                  1 | On Loan: —       |
| EXELIXIS INC                      | EXELIXIS INC                                              | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |   1824200 | NS      | $32142404.00  | 1.81%             |  |  |  | No            |                  1 | On Loan: No      |
| MORPHIC HOLDING INC               | MORPHIC HOLDING INC                                       | CUSIP: 61775R105<br>LEI: 549300RWWOUFLHTY1224 | Long             | EC               | CORP              | US        |    211700 | NS      | $6928941.00   | 0.39%             |  |  |  | No            |                  1 | On Loan: No      |
| T-KNIFE THERAPEUTICS INC          | T-KNIFE THERAPEUTICS INC SER B PC PP                      | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1300097 | NS      | $4979371.51   | 0.28%             |  |  |  | Yes           |                  3 | On Loan: No      |
| BIOCRYST PHARMACEUTICALS INC      | BIOCRYST PHARMACEUTICALS INC                              | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    884000 | NS      | $9326200.00   | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| AMGEN INC                         | AMGEN INC                                                 | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |     56700 | NS      | $14311080.00  | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| SAGE THERAPEUTICS INC             | SAGE THERAPEUTICS INC                                     | CUSIP: 78667J108<br>LEI: 5493000JX4BJS9W6CN35 | Long             | EC               | CORP              | US        |    215400 | NS      | $9550836.00   | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| AXSOME THERAPEUTICS INC           | AXSOME THERAPEUTICS INC                                   | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |    237500 | NS      | $17812500.00  | 1.00%             |  |  |  | No            |                  1 | On Loan: —       |
| ABBVIE INC                        | ABBVIE INC                                                | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |   2159880 | NS      | $319122270.00 | 17.94%            |  |  |  | No            |                  1 | On Loan: No      |
| BLUEPRINT MEDICINES CORP          | BLUEPRINT MEDICINES CORP                                  | CUSIP: 09627Y109<br>LEI: 5299004CC60O9T5HVM83 | Long             | EC               | CORP              | US        |   1232730 | NS      | $57617800.20  | 3.24%             |  |  |  | No            |                  1 | On Loan: No      |
| SONOMA BIOTHERAPEUTICS INC        | SONOMA BIOTHERAPEUTICS INC SER B1 PFD PP                  | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1049456 | NS      | $2130395.68   | 0.12%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AFFERENT PHARMA                   | AFFERENT PHARMACEUTICALS INC SER C PC PP                  | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1915787 | NS      | $19.16        | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| FUSION PHARMACEUTICALS INC        | FUSION PHARMACEUTICALS INC                                | CUSIP: 36118A100<br>LEI: N/A                  | Long             | EC               | CORP              | CA        |   1546014 | NS      | $4684422.42   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| SAREPTA THERAPEUTICS INC          | SAREPTA THERAPEUTICS INC                                  | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |     71500 | NS      | $8935355.00   | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| ASTRIA THERAPEUTICS INC           | ASTRIA THERAPEUTICS INC                                   | CUSIP: 04635X102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1411190 | NS      | $19403862.50  | 1.09%             |  |  |  | No            |                  1 | On Loan: No      |
| INTRA-CELLULAR THERAPIES INC      | INTRA-CELLULAR THERAPIES INC                              | CUSIP: 46116X101<br>LEI: 5299002U2KGF193IJA20 | Long             | EC               | CORP              | US        |    250700 | NS      | $12013544.00  | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| SONOMA BIOTHERAPEUTICS INC        | SONOMA BIOTHERAPEUTICS INC SER B PFD PP                   | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1967762 | NS      | $3286162.54   | 0.18%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AFFERENT PHARMA                   | AFFERENT PHARMACEUTICALS INC CONTINGENT VALUE RT 12/31/24 | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |   1915787 | NS      | $2145681.44   | 0.12%             |  |  |  | No            |                  3 | On Loan: No      |
| REGENERON PHARMACEUTICALS INC     | REGENERON PHARMACEUTICALS INC                             | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |    216992 | NS      | $164581922.24 | 9.25%             |  |  |  | No            |                  1 | On Loan: No      |
| PEPGEN INC                        | PEPGEN INC                                                | CUSIP: 713317105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    697100 | NS      | $10888702.00  | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| ZENTALIS PHARMACEUTICALS INC      | ZENTALIS PHARMACEUTICALS LLC                              | CUSIP: 98943L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    490692 | NS      | $11580331.20  | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| VERVE THERAPEUTICS INC            | VERVE THERAPEUTICS INC                                    | CUSIP: 92539P101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    630594 | NS      | $14346013.50  | 0.81%             |  |  |  | No            |                  1 | On Loan: —       |
| PROTHENA CORP PLC                 | PROTHENA CORP PLC                                         | CUSIP: N/A<br>LEI: 5299009ZXQ8NIIJ8OL30       | Long             | EC               | CORP              | IE        |    171900 | NS      | $9720945.00   | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| BIOGEN INC                        | BIOGEN INC                                                | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |     30400 | NS      | $8843360.00   | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| ARVINAS INC                       | ARVINAS INC                                               | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    244500 | NS      | $8012265.00   | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| GH RESEARCH PLC                   | GH RESEARCH PLC                                           | CUSIP: N/A<br>LEI: 875500HKJS7QQG6EWH62       | Long             | EC               | CORP              | IE        |    385500 | NS      | $3427095.00   | 0.19%             |  |  |  | No            |                  1 | On Loan: —       |
| WUGEN INC                         | WUGEN INC SER B PC PP                                     | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    580277 | NS      | $3029045.94   | 0.17%             |  |  |  | Yes           |                  3 | On Loan: No      |
| MOONLAKE IMMUNOTHERAPEUTICS       | MOONLAKE IMMUNOTHERAPEUTICS                               | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |    185500 | NS      | $2216725.00   | 0.12%             |  |  |  | No            |                  1 | On Loan: —       |
| SCHOLAR ROCK HOLDING CORP         | SCHOLAR ROCK HOLDING CORP                                 | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |    487376 | NS      | $5897249.60   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| LONGBOARD PHARMACEUTICALS INC     | LONGBOARD PHARMACEUTICALS INC                             | CUSIP: 54300N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    962713 | NS      | $4101157.38   | 0.23%             |  |  |  | No            |                  1 | On Loan: —       |
| KEROS THERAPEUTICS INC            | KEROS THERAPEUTICS                                        | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    599500 | NS      | $35112715.00  | 1.97%             |  |  |  | No            |                  1 | On Loan: No      |
| LIFEMINE THERAPEUTICS INC         | LIFEMINE THERAPEUTICS INC SER C PP                        | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1950028 | NS      | $3588051.52   | 0.20%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ARGENX SE                         | ARGENX SE SPONSORED ADR                                   | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |    199400 | NS      | $76220650.00  | 4.28%             |  |  |  | No            |                  1 | On Loan: No      |
| CEREVEL THERAPEUTICS HOLDINGS INC | CEREVEL THERAPEUTICS HOLDINGS INC                         | CUSIP: 15678U128<br>LEI: 254900RJNIRS9COSQR41 | Long             | EC               | CORP              | US        |    613338 | NS      | $20945492.70  | 1.18%             |  |  |  | No            |                  1 | On Loan: —       |
| INSTIL BIO INC                    | INSTIL BIO INC                                            | CUSIP: 45783C101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1041260 | NS      | $847481.51    | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| DICE THERAPEUTICS INC             | DICE MOLECULES HOLDING LLC                                | CUSIP: 23345J104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    328700 | NS      | $10442799.00  | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| EDGEWISE THERAPEUTICS INC         | EDGEWISE THERAPEUTICS INC                                 | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1459200 | NS      | $14927616.00  | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| ALKERMES PLC                      | ALKERMES PLC                                              | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | IE        |    484200 | NS      | $13867488.00  | 0.78%             |  |  |  | No            |                  1 | On Loan: No      |
| POSEIDA THERAPEUTICS INC          | POSEIDA THERAPEUTICS INC                                  | CUSIP: 73730P108<br>LEI: 549300USKSDMNGMN8V04 | Long             | EC               | CORP              | US        |    482846 | NS      | $3360608.16   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| TYRA BIOSCIENCES INC              | TYRA BIOSCIENCES INC                                      | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    730700 | NS      | $7760034.00   | 0.44%             |  |  |  | No            |                  1 | On Loan: —       |
| SHATTUCK LABS INC                 | SHATTUCK LABS INC                                         | CUSIP: 82024L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    706434 | NS      | $2945829.78   | 0.17%             |  |  |  | No            |                  1 | On Loan: —       |
| BOUNDLESS BIO INC                 | BOUNDLESS BIO INC SER B PC PP                             | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   3703704 | NS      | $3370370.64   | 0.19%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ARCUTIS BIOTHERAPEUTICS INC       | ARCUTIS BIOTHERAPEUTICS INC                               | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    898694 | NS      | $14891359.58  | 0.84%             |  |  |  | No            |                  1 | On Loan: —       |
| JANUX THERAPEUTICS INC            | JANUX THERAPEUTICS INC                                    | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    456700 | NS      | $10143307.00  | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| IMARA INC                         | IMARA INC                                                 | CUSIP: 45249V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    739725 | NS      | $3417529.50   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| RELAY THERAPEUTICS INC            | RELAY THERAPEUTICS INC                                    | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    360400 | NS      | $7734184.00   | 0.43%             |  |  |  | No            |                  1 | On Loan: —       |
| PRELUDE THERAPEUTICS INC          | PRELUDE THERAPEUTICS INC                                  | CUSIP: 74065P101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1480401 | NS      | $9444958.38   | 0.53%             |  |  |  | No            |                  1 | On Loan: —       |
| VAXCYTE INC                       | VAXCYTE INC                                               | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |    558329 | NS      | $25320220.15  | 1.42%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC PHARMACEUTICALS INC          | ORIC PHARMACEUTICALS INC                                  | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |   1206016 | NS      | $6826050.56   | 0.38%             |  |  |  | No            |                  1 | On Loan: —       |
| TANGO THERAPEUTICS INC            | TANGO THERAPEUTICS INC                                    | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1553891 | NS      | $10255680.60  | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| VERA THERAPEUTICS INC             | VERA THERAPEUTICS INC                                     | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    980468 | NS      | $8314368.64   | 0.47%             |  |  |  | No            |                  1 | On Loan: —       |
| VERONA PHARMA PLC                 | VERONA PHARMA PLC ADR                                     | CUSIP: 925050106<br>LEI: 213800EVI6O6J3TIAL06 | Long             | EC               | CORP              | GB        |    484367 | NS      | $10675448.68  | 0.60%             |  |  |  | No            |                  1 | On Loan: No      |
| CYTEIR THERAPEUTICS INC           | CYTEIR THERAPEUTICS INC                                   | CUSIP: 23284P103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1419670 | NS      | $2172095.10   | 0.12%             |  |  |  | No            |                  1 | On Loan: —       |
| ACELYRIN INC                      | ACELYRIN INC                                              | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |   1343629 | NS      | $8357506.74   | 0.47%             |  |  |  | No            |                  3 | On Loan: No      |
| IKENA ONCOLOGY INC                | IKENA ONCOLOGY INC                                        | CUSIP: 45175G108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   2134326 | NS      | $9092228.76   | 0.51%             |  |  |  | No            |                  1 | On Loan: —       |
| ACELYRIN INC                      | ACELYRIN INC CVR RT                                       | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |    163271 | NS      | $967627.21    | 0.05%             |  |  |  | No            |                  3 | On Loan: No      |
| KARUNA THERAPEUTICS INC           | KARUNA THERAPEUTICS INC                                   | CUSIP: 48576A100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    198167 | NS      | $39512518.13  | 2.22%             |  |  |  | No            |                  1 | On Loan: No      |
| AEROVATE THERAPEUTICS INC         | AEROVATE THERAPEUTICS INC                                 | CUSIP: 008064107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    322400 | NS      | $7366840.00   | 0.41%             |  |  |  | No            |                  1 | On Loan: —       |
| FOG PHARMACEUTICALS INC           | FOG PHARMACEUTICALS INC SER D PC PP                       | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    239281 | NS      | $2575405.33   | 0.14%             |  |  |  | Yes           |                  3 | On Loan: No      |
| VENTYX BIOSCIENCES INC            | VENTYX BIOSCIENCES INC                                    | CUSIP: 92332V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    404730 | NS      | $16998660.00  | 0.96%             |  |  |  | No            |                  1 | On Loan: —       |
| CYTOKINETICS INC                  | CYTOKINETICS INC                                          | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |   1273471 | NS      | $54097048.08  | 3.04%             |  |  |  | No            |                  1 | On Loan: —       |
| TREELINE BIOSCIENCES              | TREELINE BIOSCIENCES SERIES A PC PP                       | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |     47600 | NS      | $400316.00    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| SCHOLAR ROCK HOLDING CORP         | SCHOLAR ROCK HOLDING CORP WT 12/31/2025 PP                | CUSIP: N/A<br>LEI: 549300Z1FLPGL4OWJ459       | Long             | EC               | CORP              | US        |      6000 | NS      | $39161.68     | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| ARISTEA THERAPEUTICS INC          | ARISTEA THERAPEUTICS INC SER B PC PP                      | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    677328 | NS      | $3732077.28   | 0.21%             |  |  |  | Yes           |                  3 | On Loan: No      |
| DIANTHUS THERAPEUTICS INC         | DIANTHUS THERAPEUTICS INC SER A PC PP                     | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    906629 | NS      | $3925703.57   | 0.22%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Fidelity Revere Street Trust      | Fidelity Cash Central Fund                                | CUSIP: 31635A105<br>LEI: 549300BDV45LJNXBZC55 | Long             | STIV             | RF                | US        |  12408387 | NS      | $12410868.94  | 0.70%             |  |  |  | No            |                  1 | On Loan: No      |
| ASCENDIS PHARMA A/S               | ASCENDIS PHARMA AS SPON ADR                               | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |    506125 | NS      | $62799990.00  | 3.53%             |  |  |  | No            |                  1 | On Loan: —       |
| VERTEX PHARMACEUTICALS INC        | VERTEX PHARMACEUTICALS INC                                | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |    356227 | NS      | $115096943.70 | 6.47%             |  |  |  | No            |                  1 | On Loan: No      |
| APOGEE THERAPEUTICS               | APOGEE THERAPEUTICS SER B PC PP                           | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1039132 | NS      | $3433874.04   | 0.19%             |  |  |  | Yes           |                  3 | On Loan: No      |
| BIOHAVEN LTD                      | BIOHAVEN LTD                                              | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | VG        |    282300 | NS      | $5389107.00   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| PHARVARIS BV                      | PHARVARIS BV                                              | CUSIP: N/A<br>LEI: 9845003BE146D3B75D32       | Long             | EC               | CORP              | NL        |    372633 | NS      | $3353697.00   | 0.19%             |  |  |  | No            |                  1 | On Loan: —       |
| MADRIGAL PHARMACEUTICALS INC      | MADRIGAL PHARMACEUTICALS INC                              | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |     18100 | NS      | $5217325.00   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| EXACT SCIENCES CORP               | EXACT SCIENCES CORP                                       | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |    270800 | NS      | $18284416.00  | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ICOSAVAX INC                      | ICOSAVAX INC                                              | CUSIP: 45114M109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1897931 | NS      | $20023172.05  | 1.13%             |  |  |  | No            |                  1 | On Loan: —       |
| PTC THERAPEUTICS INC              | PTC THERAPEUTICS INC                                      | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |    486440 | NS      | $22322731.60  | 1.25%             |  |  |  | No            |                  1 | On Loan: No      |
| ARCELLX INC                       | ARCELLX INC                                               | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    177700 | NS      | $5936957.00   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| STOKE THERAPEUTICS INC            | STOKE THERAPEUTICS INC                                    | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |    446619 | NS      | $4448325.24   | 0.25%             |  |  |  | No            |                  1 | On Loan: —       |
| DAY ONE BIOPHARMACEUTICALS INC    | DAY ONE BIOPHARMACEUTICALS INC                            | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    863569 | NS      | $18799897.13  | 1.06%             |  |  |  | No            |                  1 | On Loan: No      |
| ALNYLAM PHARMACEUTICALS INC       | ALNYLAM PHARMACEUTICALS INC                               | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |    350686 | NS      | $79395310.40  | 4.46%             |  |  |  | No            |                  1 | On Loan: No      |
| Fidelity Revere Street Trust      | Fidelity Securities Lending Cash Central Fund             | CUSIP: 31635A303<br>LEI: 549300BDV45LJNXBZC55 | Long             | STIV             | RF                | US        | 164031100 | NS      | $164047503.15 | 9.22%             |  |  |  | No            |                  1 | On Loan: No      |
| XENON PHARMACEUTICALS INC         | XENON PHARMACEUTICALS INC                                 | CUSIP: 98420N105<br>LEI: 549300XV44Q9Z1MIPQ03 | Long             | EC               | CORP              | CA        |   1061058 | NS      | $41476757.22  | 2.33%             |  |  |  | No            |                  1 | On Loan: No      |
| GILEAD SCIENCES INC               | GILEAD SCIENCES INC                                       | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |    484900 | NS      | $40702506.00  | 2.29%             |  |  |  | No            |                  1 | On Loan: No      |
| ALX ONCOLOGY HOLDINGS INC         | ALX ONCOLOGY HOLDINGS INC                                 | CUSIP: 00166B105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1191906 | NS      | $11084725.80  | 0.62%             |  |  |  | No            |                  1 | On Loan: —       |
| VIKING THERAPEUTICS INC           | VIKING THERAPEUTICS INC                                   | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    547600 | NS      | $4796976.00   | 0.27%             |  |  |  | No            |                  1 | On Loan: —       |
| IMARA INC                         | ENLIVEN THERAPEUTICS INC                                  | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |   2110376 | NS      | $8774943.41   | 0.49%             |  |  |  | No            |                  2 | On Loan: No      |
| CELLDEX THERAPEUTICS INC          | CELLDEX THERAPEUTICS INC                                  | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |    901207 | NS      | $39707180.42  | 2.23%             |  |  |  | No            |                  1 | On Loan: No      |
| BRIGHT PEAK THERAPEUTICS AG       | BRIGHT PEAK THERAPEUTICS SER B PC PP                      | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | CH        |   1920122 | NS      | $5645158.68   | 0.32%             |  |  |  | Yes           |                  3 | On Loan: No      |
| NUVALENT INC                      | NUVALENT INC-A                                            | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    735406 | NS      | $22246031.50  | 1.25%             |  |  |  | No            |                  1 | On Loan: —       |
| MONTE ROSA THERAPEUTICS INC       | MONTE ROSA THERAPEUTICS INC                               | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    698958 | NS      | $5172289.20   | 0.29%             |  |  |  | No            |                  1 | On Loan: —       |

### Signature

**Date Signed:** 2023-03-02

**Name of Applicant:** Stacie M. Smith

**Signature:** Stacie M. Smith

**Name of Signer:** Stacie M. Smith

**Title:** President and Treasurer