# EDGAR Filing Document

**Accession Number:** 0001463928
**File Stem:** 0001104659-23-000324
**Filing Date:** 2023-1
**Character Count:** 28135
**Document Hash:** 2e0467979c106496d5fa227c3cc6c046
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-23-000324.hdr.sgml**: 20230103

**ACCESSION NUMBER**: 0001104659-23-000324

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20230103

**DATE AS OF CHANGE**: 20230103

**GROUP MEMBERS**: MARK ANGELO

**GROUP MEMBERS**: YA GLOBAL INVESTMENTS II (U.S.), LP

**GROUP MEMBERS**: YA II GP, LP

**GROUP MEMBERS**: YAII GP II, LLC

**GROUP MEMBERS**: YORKVILLE ADVISORS GLOBAL II, LLC

**GROUP MEMBERS**: YORKVILLE ADVISORS GLOBAL, LP

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** NLS Pharmaceutics Ltd.
- **CENTRAL INDEX KEY:** 0001783036
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** V8
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-92065
- **FILM NUMBER:** 23501976

**BUSINESS ADDRESS:**
- **STREET 1:** THE CIRCLE 6
- **STREET 2:** 8058
- **CITY:** ZURICH
- **STATE:** V8
- **ZIP:** CH-6370
- **BUSINESS PHONE:** 41-41-618-80-00

**MAIL ADDRESS:**
- **STREET 1:** THE CIRCLE 6
- **STREET 2:** 8058
- **CITY:** ZURICH
- **STATE:** V8
- **ZIP:** CH-6370
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** YA II PN, Ltd.
- **CENTRAL INDEX KEY:** 0001463928
- **IRS NUMBER:** 980615492
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** 101 HUDSON STREET #3700
- **CITY:** JERSEY CITY
- **STATE:** NJ
- **ZIP:** 07302
- **BUSINESS PHONE:** 201 985 8300

**MAIL ADDRESS:**
- **STREET 1:** 101 HUDSON STREET #3700
- **CITY:** JERSEY CITY
- **STATE:** NJ
- **ZIP:** 07302

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** YA GLOBAL MASTER SPV, LTD.
- **DATE OF NAME CHANGE:** 20130604

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** YA GLOBAL MASTER SPV LLC
- **DATE OF NAME CHANGE:** 20090512

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

**AMENDMENT NO. 2 TO SCHEDULE 13G**

Under the Securities Exchange Act of 1934

**<u>NLS Pharmaceutics Ltd.</u>**

**(Name of Issuer)**

------

**<u>Common Shares, nominal value of CHF 0.02 per share</u>**

**(Title of Class of Securities)**

**H57830103**

**(CUSIP Number)**

**December 31, 2022**

------

**(Date of Event, which Requires Filing of this Statement)**

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

◻ Rule 13d-1(b) <br> ⌧ Rule 13d-1(c) <br> ◻ Rule 13d-1(d)

\*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information, which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purposes of Section 18 of the Securities and Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act out shall be subject to all other provisions of the Act, (however, see the Notes).

---

| | |
|:---|:---|
| **CUSIP No. **H57830103** | **CUSIP No. **H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>YA II PN, Ltd.<br> 98-0615462 |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: Cayman Islands  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

---

| | |
|:---|:---|
| **CUSIP No. H57830103** | **CUSIP No. H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>YA Global Investments II (U.S.), LP<br> 42-1766918 |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: Delaware  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

---

| | |
|:---|:---|
| **CUSIP No. H57830103** | **CUSIP No. H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>Yorkville Advisors Global, LP<br> 90-0860458 |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: Delaware  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

---

| | |
|:---|:---|
| **CUSIP No. H57830103** | **CUSIP No. H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>Yorkville Advisors Global II, LLC<br> 81-4918579 |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: Delaware  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

---

| | |
|:---|:---|
| **CUSIP No. H57830103** | **CUSIP No. H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>YA II GP, LP<br> 80-0827189 |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: Delaware  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

---

| | |
|:---|:---|
| **CUSIP No. H57830103** | **CUSIP No. H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>YAII GP II, LLC |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: Delaware  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

---

| | |
|:---|:---|
| **CUSIP No. H57830103** | **CUSIP No. H57830103** |
| 1. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Names of Reporting Persons.I.R.S. Identification Nos. of above persons (entities only)<br>Mark Angelo |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)(a) ⌧<br> (b) ◻ |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization: U.S.A.  |

---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | &nbsp;&nbsp;5. | &nbsp;&nbsp;Sole Voting Power:  | &nbsp;&nbsp;0<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 6 | Shared Voting Power:  | 3,047,011\*<br>|
| &nbsp;&nbsp;Number of<br> Shares<br> Beneficially<br> Owned by<br> Each<br> Reporting<br> Person With | 7. | Sole Dispositive Power:  | 0<br>|
|  | 8. | Shared Dispositive Power: | 3,047,011\* |

---

9. Aggregate
 Amount Beneficially Owned by Each Reporting Person: 3,047,011\*

10. Check
 if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ◻

11. Percentage of Class Represented
 by Amount in Row (9): 9.99%\*\*

12. Type
 of Reporting Person (See Instructions): OO

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.4

**Item 1.**

&nbsp;&nbsp;&nbsp;&nbsp;(a) **Name of Issuer:** 

NLS Pharmaceutics Ltd.

&nbsp;&nbsp;&nbsp;&nbsp;(b) **Address of Issuer's Principal Executive Offices** 

Alter Postplatz 2

CH-6370 Stans, Switzerland

**Item 2.** **<u>Identity and Background</u>.**

&nbsp;&nbsp;&nbsp;&nbsp;(a) **Name of Person Filing:** 

YA II PN, Ltd.

&nbsp;&nbsp;&nbsp;&nbsp;(b) **Address of Principal Executive Office or, if none, Residence of Reporting Persons:** 

1012 Springfield Ave.

Mountainside, NJ 07092

&nbsp;&nbsp;&nbsp;&nbsp;(c) **Citizenship:** 

Cayman Islands

&nbsp;&nbsp;&nbsp;&nbsp;(d) **Title of Class of Securities:** 

Common shares, nominal value of CHF 0.02 per share

&nbsp;&nbsp;&nbsp;&nbsp;(e) **CUSIP Number:** 

H57830103

**Item 3.** **If the statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is:**

(a) ◻ Broker or dealer registered under section 15 of
 the Act (15 U.S.C. 78o);

(b) ◻ Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

(c) ◻ Insurance company as defined in section 3(a)(19) of the Act
 (15 U.S.C. 78c);

(d) ◻ Investment company registered under section 8 of the Investment
 Company Act of 1940 (15 of the Act (15 U.S.C. 78o);

(e) ◻ An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

(f) ◻ An employee benefit plan or endowment fund in accordance with
 §240.13d-1(b)(1)(ii)(F);

(g) ◻ A parent holding company or control person in accordance with
 §240.13d-1(b)(1)(ii)(G);

(h) ◻ A savings associations as defined in Section 3(b) of the Federal
 Deposit Insurance Act (12 U.S.C. 1813);

(i) ◻ A church plan that is excluded from the definition of an
 investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j) ◻ A non-U.S. institution in accordance with §240.13d-1(b)(1)(ii)(J);
 or

(k) ⌧ Group, in accordance with 240.13d(b)(1)(ii)(K).

**Item 4.** **<u>Ownership</u>**

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

&nbsp;&nbsp;&nbsp;&nbsp;(a) Amount beneficially owned: 3,047,011\*

&nbsp;&nbsp;&nbsp;&nbsp;(b) Percentage of Class: 9.99%\*\*

&nbsp;&nbsp;&nbsp;&nbsp;(c) Number of shares as to which the person has:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) Sole Power to vote or to direct the vote: 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii) Shared power to vote or to direct the vote: 3,047,011\*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii) Sole power to dispose or to direct the disposition: 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iv) Shared power to dispose or to direct the disposition: 3,047,011\*

\* 3,047,011 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,047,011 share of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

\*\* Calculation based on 30,500,614 outstanding shares of issuer's Common Stock, consisting of 27,453,603 shares of Common Stock outstanding shares as of the date of this report and an additional 3,047,011 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

**Item 5.** **<u>Ownership of Five Percent or Less of a Class</u>:**

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ◻.

**Item 6.** **<u>Ownership of more than five percent on Behalf of Another Person</u>.**

The reporting persons directly or indirectly own an aggregate of 3,047,011\* shares, or 9.99%, of Common Stock of the issuer as of December 31, 2021. YA II and the other reporting persons share the power to vote and dispose of any such Common Stock.

***Direct*** beneficial ownership of such Common Stock by the reporting persons is as follows (and therefore *excludes* any Common Stock indirectly held by such person or any securities, such as warrants, which may be exercised or converted into Common Stock of the issuer):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· YA
 II PN, Ltd. – 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· YA
 Global Investments II (U.S.), LP -- 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· YA Global II SPV, LLC – 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Yorkville
 Advisors Global, LP – 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Yorkville
 Advisors Global II, LLC – 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· YA
 II GP, LP – 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· YAII
 GP II, LLC – 0

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Mark
 Angelo – 0

***Indirect*** beneficial ownership: YA II PN, Ltd. ("<u>YA II</u>") entered into a Standby Equity Distribution Agreement ("<u>SEDA</u>") with the issuer dated as of September 27, 2021. Under the SEDA, the issuer has the option to sell its common shares to YA II at a price and on the terms and subject to the conditions set forth in the SEDA. Under the SEDA, the issuer is prohibited from selling shares to YA II to the extent that it would cause the aggregate number of shares beneficially owned by YA II and its affiliates to exceed 9.99% of the shares of the issuer. In addition to the direct beneficial ownership set forth above, each reporting person is also deemed to be the ***indirect*** beneficial owner of additional shares of Common Stock that the issuer has the right to sell to the reporting persons under a SEDA within 60 days of the date of this filing such that each reporting person is deemed to be the indirect beneficial owner of an additional 3,047,011\* shares of Common Stock.

Below is a description of the relationship among the reporting persons:

YA II is beneficially owned by YA Global Investments II (U.S.), LP (the "<u>YA Feeder</u>"). YA Global II, SPV ("<u>YA SPV</u>") is a wholly-owned subsidiary of YA II. Yorkville Advisors Global, LP (the "<u>YA Advisor</u>") is the investment manager to YA II. Yorkville Advisors Global II, LLC (the "<u>YA Advisor GP</u>") is the general partner to the YA Advisor. YA II GP, LP (the "<u>YA GP</u>") is the general partner to the YA Feeder. YAII GP II, LLC (the "<u>Yorkville GP</u>") is the general partner to the YA GP. Mark Angelo makes the investment decisions on behalf of YA II. Accordingly, each of YA II, YA SPV, YA Feeder, the YA Advisor, the YA Advisor GP, the YA GP, the Yorkville GP and Mark Angelo may be deemed affiliates and therefore may be deemed to beneficially own the same number of shares of Common Stock.

For purposes of this filing, each of the reporting persons is deemed an affiliate of each other reporting person.

**Item 7.** **<u>Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.</u>**

Not Applicable

**Item 8.** **<u>Identification and Classification of Member Group</u>**

See Item 6.

**Item 9.** **<u>Notice of Dissolution of Group</u>**

Not Applicable

**Item 10.** **<u>Certification</u>**

By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as participant in any transaction having that purpose or effect.

**<u>Additional Information</u>** **:**

Each Reporting Person disclaims beneficial ownership of any securities beneficially owned by each other Reporting Person, and its report shall not be deemed to be an admission that any Reporting Person is the beneficial owner of these securities for the purpose of Section 16 or for any other purpose.

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement in true, complete and correct.

---

| | |
|:---|:---|
| Dated: January 3, 2023 | Dated: January 3, 2023 |
|  | **<u>REPORTING PERSON:</u>** |
| **YA II PN, Ltd.** | **YA II PN, Ltd.** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **YA Global Investments II (U.S.), Ltd.** | **YA Global Investments II (U.S.), Ltd.** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **Yorkville Advisors Global, LP** | **Yorkville Advisors Global, LP** |
| **By: Yorkville Advisors Global, LLC** | **By: Yorkville Advisors Global, LLC** |
| **Its: General Partner** | **Its: General Partner** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |

---

---

| | |
|:---|:---|
| **Yorkville Advisors Global II, LLC** | **Yorkville Advisors Global II, LLC** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **YA II GP, LP** | **YA II GP, LP** |
| **By: YAII GP II, LLC** | **By: YAII GP II, LLC** |
| **Its: General Partner** | **Its: General Partner** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **YAII GP II, LLC** | **YAII GP II, LLC** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |

---

## Exhibit 99.1

**EXHIBIT 99.1**

**JOINT FILING AGREEMENT** 

The undersigned hereby agree that the statement on Schedule 13G with respect to the equity securities of NLS Pharmaceutics Ltd. is, and any amendment thereto signed by each of the undersigned shall be, filed on behalf of each of the undersigned pursuant to and in accordance with the provisions of Rule 13d-1(k) promulgated under the Securities Exchange Act of 1934, as amended. The undersigned hereby further agree that this Joint Filing Agreement be included as an exhibit to such statement and any such amendment. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him or it contained herein and therein but shall not be responsible for the completeness and accuracy of the information concerning the others. This Joint Filing Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.

Dated: January 3, 2023

---

| | |
|:---|:---|
| **YA II PN, Ltd.** | **YA II PN, Ltd.** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |

---

---

| | |
|:---|:---|
| **YA Global Investments II (U.S.), Ltd.** | **YA Global Investments II (U.S.), Ltd.** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **Yorkville Advisors Global, LP** | **Yorkville Advisors Global, LP** |
| **By: Yorkville Advisors Global, LLC** | **By: Yorkville Advisors Global, LLC** |
| **Its: General Partner** | **Its: General Partner** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **Yorkville Advisors Global II, LLC** | **Yorkville Advisors Global II, LLC** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |

---

---

| | |
|:---|:---|
| **YA II GP, LP** | **YA II GP, LP** |
| **By: YAII GP II LLC** | **By: YAII GP II LLC** |
| **Its: General Partner** | **Its: General Partner** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |
| **YAII GP II LLC** | **YAII GP II LLC** |
| By: | /s/ Robert Munro |
|  | Robert Munro |
|  | Chief Compliance Officer |

---