# EDGAR Filing Document

**Accession Number:** 0001622229
**File Stem:** 0001214659-23-002279
**Filing Date:** 2023-2
**Character Count:** 16248
**Document Hash:** 5aa8908f99087627199da24499e1e519
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001214659-23-002279.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0001214659-23-002279

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230214

**DATE AS OF CHANGE**: 20230214

**GROUP MEMBERS**: CHEN YU

**GROUP MEMBERS**: TCG CROSSOVER FUND I, L.P.

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Cogent Biosciences, Inc.
- **CENTRAL INDEX KEY:** 0001622229
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 465308248
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-90431
- **FILM NUMBER:** 23627109

**BUSINESS ADDRESS:**
- **STREET 1:** 275 WYMAN STREET
- **STREET 2:** 3RD FLOOR
- **CITY:** WALTHAM
- **STATE:** MA
- **ZIP:** 02451
- **BUSINESS PHONE:** 617-945-5576

**MAIL ADDRESS:**
- **STREET 1:** 275 WYMAN STREET
- **STREET 2:** 3RD FLOOR
- **CITY:** WALTHAM
- **STATE:** MA
- **ZIP:** 02451

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Unum Therapeutics Inc.
- **DATE OF NAME CHANGE:** 20180402

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Unum Therapeutics, Inc.
- **DATE OF NAME CHANGE:** 20141014
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** TCG Crossover GP I, LLC
- **CENTRAL INDEX KEY:** 0001839947
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** 228 HAMILTON AVENUE, 3RD FLOOR
- **CITY:** PALO ALTO
- **STATE:** CA
- **ZIP:** 94301
- **BUSINESS PHONE:** 650-798-5495

**MAIL ADDRESS:**
- **STREET 1:** 228 HAMILTON AVENUE, 3RD FLOOR
- **CITY:** PALO ALTO
- **STATE:** CA
- **ZIP:** 94301

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**SCHEDULE 13G**

**Under the Securities Exchange Act of 1934**

 **(Amendment No. 2)\*** 

---

| |
|:---|
| **Cogent Biosciences, Inc.** |
| (Name of Issuer) |
| **Common Stock, $0.001 par value** |
| (Title of Class of Securities) |

---

---

| |
|:---|
| **19240Q 201** |
| (CUSIP Number) |
| **December 31, 2022** |
| (Date of Event Which Requires Filing of This Statement) |

---

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

⌧ Rule 13d-1(c)

☐ Rule 13d-1(d)

\*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP No. 19240Q 201 13G

1. NAMES OF REPORTING PERSONS TCG Crossover GP I, LLC

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (see instructions) (a) □ (b) ⌧

3. SEC USE ONLY

4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware

---

| | | |
|:---|:---|:---|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH | 5. | SOLE VOTING POWER<br>0 |
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH | 6. | SHARED VOTING POWER<br>3,631,042 (1)  |
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH | 7. | SOLE DISPOSITIVE POWER<br>0 |
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH | 8. | SHARED DISPOSITIVE POWER<br>3,631,042 (1)  |

---

9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,631,042 (1)

10. CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (see
 instructions) ☐

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.2% (2)

12. TYPE OF REPORTING PERSON (see instructions) OO

(1) Consists of 3,631,042 shares of Common Stock (as defined
 in Item 2(d) below) of the Issuer (as defined in Item 1(a) below) held of record by TCG Crossover I (as defined in Item 2(a) below).
 TCG Crossover GP I (as defined in Item 2(a) below) is the general partner of TCG Crossover I and may be deemed to have voting, investment,
 and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP I and may be deemed
 to share voting, investment and dispositive power with respect to these securities.

(2) Based on 69,893,434 outstanding shares of Common Stock as
 of November 11, 2022 as reported by the Issuer in its Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission
 (the "Commission") on November 14, 2022 (the "Form 10-Q").

CUSIP No. 19240Q 201 13G

1. NAMES OF REPORTING PERSONS TCG Crossover Fund I,
 L.P.

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (see instructions) (a) □ (b) ⌧

3. SEC USE ONLY

4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware

---

| | | |
|:---|:---|:---|
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 5. | SOLE VOTING POWER <br>0  |
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 6. | SHARED VOTING POWER <br>3,631,042 (1)  |
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 7. | SOLE DISPOSITIVE POWER <br>0  |
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 8. | SHARED DISPOSITIVE POWER <br>3,631,042 (1)  |

---

9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,631,042 (1)

10. CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
 (see instructions) ☐

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.2% (2)

12. TYPE OF REPORTING PERSON (see instructions) PN

(1) Consists of 3,631,042 shares of Common Stock of the
 Issuer held of record by TCG Crossover I. TCG Crossover GP I is the general partner of TCG Crossover I and may be deemed to have
 voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover
 GP I and may be deemed to share voting, investment and dispositive power with respect to these securities.

(2) Based on 69,893,434 outstanding shares of Common Stock as
 of November 11, 2022 as reported by the Issuer in the Form 10-Q.

CUSIP No. 19240Q 201 13G

1. NAMES OF REPORTING PERSONS Chen Yu

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (see instructions) (a) □ (b) ⌧

3. SEC USE ONLY

4. CITIZENSHIP OR PLACE OF ORGANIZATION United States of America

---

| | | |
|:---|:---|:---|
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 5. | SOLE VOTING POWER <br>0  |
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 6. | SHARED VOTING POWER <br>3,631,042 (1)  |
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 7. | SOLE DISPOSITIVE POWER <br>0  |
| NUMBER OF <br> SHARES <br> BENEFICIALLY <br> OWNED BY <br> EACH <br> REPORTING <br> PERSON <br> WITH  | 8. | SHARED DISPOSITIVE POWER <br>3,631,042 (1)  |

---

9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,631,042 (1)

10. CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
 (see instructions) ☐

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.2% (2)

12. TYPE OF REPORTING PERSON (see instructions) IN

(1) Consists of 3,631,042 shares of Common Stock of the
 Issuer held of record by TCG Crossover I. TCG Crossover GP I is the general partner of TCG Crossover I and may be deemed to have
 voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover
 GP I and may be deemed to share voting, investment and dispositive power with respect to these securities.

(2) Based on 69,893,434 outstanding shares of Common Stock as
 of November 11, 2022 as reported by the Issuer in the Form 10-Q.

CUSIP No. 19240Q 201 13G

 **Explanatory Note** <br>This Amendment No. 2 amends and restates the statement on Schedule 13G initially filed by TCG Crossover Management, LLC with the Securities and Exchange Commission on July 8, 2021, as amended by Amendment No. 1 filed with the Commission on November 17, 2021 (the "Original Schedule 13G"). <br>

---

| | |
|:---|:---|
| **Item 1(a).** | **Name of Issuer:** |

---

Cogent Biosciences, Inc. (the "Issuer").

---

| | |
|:---|:---|
| **Item 1(b).** | **Address of Issuer's Principal Executive Offices:** |

---

200 Cambridge Park Drive, Suite 2500

Cambridge, Massachusetts 02140<br>

---

| | |
|:---|:---|
| **Item 2(a).** | **Name of Person Filing:** |

---

This joint statement on Schedule 13G is being filed by TCG Crossover Fund I, L.P. ("TCG Crossover I"), TCG Crossover GP I, LLC ("TCG Crossover GP I" and together with TCG Crossover I, the "Reporting Entities") and Chen Yu (the "Reporting Individual"). The Reporting Entities and the Reporting Individual are collectively referred to as the "Reporting Persons." The Reporting Persons expressly disclaim status as a "group" for purposes of this Schedule 13G. The agreement among the Reporting Persons to file jointly in accordance with the provisions of Rule 13d-1(k)(1) under the Act is attached to this Statement as <u>Exhibit 1</u>. Other than those securities reported herein as being held directly by such Reporting Person, each Reporting Person disclaims beneficial ownership of all securities reported in this Statement except to the extent of such Reporting Person's pecuniary interest therein.

---

| | |
|:---|:---|
| **Item 2(b)** | **Address of Principal Business Office, or if None, Residence:** |

---

The address of the principal business office of each Reporting Person is 705 High St., Palo Alto, CA 94301.

---

| | |
|:---|:---|
| **Item 2(c).** | **Citizenship:** |

---

TCG Crossover GP I is a limited liability company organized under the laws of the State of Delaware. TCG Crossover I is a limited partnership organized under the laws of the State of Delaware. The Reporting Individual is a citizen of the United States of America.

---

| | |
|:---|:---|
| **Item 2(d).** | **Title of Class of Securities:** |

---

Common Stock, $0.001 par value ("Common Stock").

---

| | |
|:---|:---|
| **Item 2(e).** | **CUSIP Number:** |

---

19240Q 201

**Item 3.** **If this statement is filed pursuant to §§ 240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:** 

Not applicable.

**Item 4.** **Ownership.** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (a) Amount beneficially owned:

See Row 9 of the cover page for each Reporting Person and the corresponding footnotes.\*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (b) Percent of class:

See Row 11 of the cover page for each Reporting Person and the corresponding footnotes.\*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (c) Number of shares as to which the person has:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (i) Sole power to vote or to direct the vote

See Row 5 of the cover page for each Reporting Person and the corresponding footnotes.\*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (ii) Shared power to vote or to direct the vote

See Row 6 of the cover page for each Reporting Person and the corresponding footnotes.\*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (iii) Sole power to dispose or to direct the disposition of

See Row 7 of the cover page for each Reporting Person and the corresponding footnotes.\*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (iv) Shared power to dispose or to direct the disposition of

See Row 8 of the cover page for each Reporting Person and the corresponding footnotes.\*

\* Except to the extent of his or its pecuniary interest therein, each Reporting Person disclaims beneficial ownership of such shares of Common Stock, except for the shares, if any, such Reporting Person holds of record.

**Item 5.** **Ownership of Five Percent or Less of a Class.** 

Not applicable.

**Item 6.** **Ownership of More Than Five Percent on Behalf of Another Person.** 

Under certain circumstances set forth in the limited partnership agreements of TCG Crossover I and the limited liability company agreement of TCG Crossover GP I, the general and limited partners or members, as the case may be, of each of such entities may be deemed to have the right to receive dividends from, or the proceeds from, the sale of securities of the Issuer owned by each such entity of which they are a partner or member, as the case may be.

**Item 7.** **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.** 

Not applicable.

**Item 8.** **Identification and Classification of Members of the Group.** 

Not applicable.

**Item 9.** **Notice of Dissolution of the Group.** 

Not applicable.

**Item 10.** **Certifications.** 

Not Applicable

 <u>Material to be Filed as Exhibits.</u> 

Exhibit 1 – Joint Filing Agreement.

CUSIP No. 19240Q 201 13G

**SIGNATURE** 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: February 14, 2023

---

| | |
|:---|:---|
|  **TCG Crossover Fund I, L.P.** | **TCG Crossover Fund I, L.P.** |
|  By: | TCG Crossover GP I, LLC |
|  Its: | General Partner |

---

---

| | |
|:---|:---|
|  By: | /s/ Chen Yu |
|  | Managing Member |
|  **TCG Crossover GP I, LLC** | **TCG Crossover GP I, LLC** |
|  By: | /s/ Chen Yu |
|  | Managing Member |
|  **Chen Yu** | **Chen Yu** |
|  /s/ Chen Yu | /s/ Chen Yu |

---

 **Exhibit 1** 

 **JOINT FILING AGREEMENT** 

The undersigned hereby agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned, and any amendments thereto executed by the undersigned shall be filed on behalf of each of the undersigned without the necessity of filing any additional joint filing agreement. The undersigned acknowledge that each is responsible for the timely filing of such statement on Schedule 13G and any amendments thereto, and for the completeness and accuracy of the information concerning him, her or it contained therein, but shall not be responsible for the completeness or accuracy of the information concerning the others of the undersigned, except to the extent that he, she or it knows or has reason to believe that such information is inaccurate or incomplete. This Joint Filing Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.

Dated: February 14, 2023

---

| | |
|:---|:---|
|  **TCG Crossover Fund I, L.P.** | **TCG Crossover Fund I, L.P.** |
|  By: | TCG Crossover GP I, LLC |
|  Its: | General Partner |

---

---

| | |
|:---|:---|
|  By: | /s/ Chen Yu |
|  | Managing Member |
|  **TCG Crossover GP I, LLC** | **TCG Crossover GP I, LLC** |
|  By: | /s/ Chen Yu |
|  | Managing Member |
|  **Chen Yu** | **Chen Yu** |
|  /s/ Chen Yu | /s/ Chen Yu |

---