# EDGAR Filing Document

**Accession Number:** 0002019410
**File Stem:** 0001104659-25-059442
**Filing Date:** 2025-6
**Character Count:** 3754
**Document Hash:** a9314fcf1f3cc8a62c8ff6363bdfe94c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-059442.hdr.sgml**: 20250828

**ACCESSION NUMBER**: 0001104659-25-059442

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250613

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Caris Life Sciences, Inc.
- **CENTRAL INDEX KEY:** 0002019410
- **STANDARD INDUSTRIAL CLASSIFICATION:** SERVICES-MEDICAL LABORATORIES [8071]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 852077369
- **STATE OF INCORPORATION:** TX
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 750 W JOHN CARPENTER FREEWAY
- **STREET 2:** SUITE 800
- **CITY:** IRVING
- **STATE:** TX
- **ZIP:** 75039
- **BUSINESS PHONE:** (866) 771-8946

**MAIL ADDRESS:**
- **STREET 1:** 750 W JOHN CARPENTER FREEWAY
- **STREET 2:** SUITE 800
- **CITY:** IRVING
- **STATE:** TX
- **ZIP:** 75039

June 13, 2025

*<u>VIA EDGAR</u>*

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549-6010

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| | |
|:---|:---|
| Attention: | Lauren Nguyen |
|  | Juan Grana |
|  | Michael Fay |
|  | Tayyaba Shafique |

---

---

| | |
|:---|:---|
| **Re:** | **Caris Life Sciences, Inc.** |
|  | **Registration Statement on Form S-1, as amended** |
|  | **File No. 333-287551** |
|  | **Acceleration Request** |
|  | **Requested Date: June 17, 2025** |
|  | **Requested Time: 4:00 P.M. Eastern Time** |

---

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended (the "**Act**"), we, as representatives of the several underwriters, hereby join in the request of Caris Life Sciences, Inc. (the "**Company**") for acceleration of the effective time of the above-referenced Registration Statement, requesting effectiveness as of 4:00 P.M., Eastern Time, on June 17, 2025, or at such later time as the Company or its outside counsel, Latham & Watkins LLP, may request via telephone call to the staff of the Division of Corporation Finance of the Securities and Exchange Commission.

Pursuant to Rule 460 under the Act, please be advised that we will take reasonable steps to secure adequate distribution of the preliminary prospectus to underwriters, dealers, institutions and others, prior to the requested effective time of the Registration Statement.

We, the undersigned, as representatives of the several underwriters, have complied and will comply, and we have been informed by the participating underwriters that they have complied and will comply, with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

*[Signature Page Follows]*

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| | |
|:---|:---|
| Very truly yours, | Very truly yours, |
| BOFA SECURITIES, INC. | BOFA SECURITIES, INC. |
| J.P. MORGAN SECURITIES LLC | J.P. MORGAN SECURITIES LLC |
| GOLDMAN SACHS & CO. LLC | GOLDMAN SACHS & CO. LLC |
| CITIGROUP GLOBAL MARKETS INC. | CITIGROUP GLOBAL MARKETS INC. |
| As representatives of the underwriters | As representatives of the underwriters |
| **BOFA SECURITIES, INC.** | **BOFA SECURITIES, INC.** |
| By: | /s/ Michael Liloia |
|  | Name: Michael Liloia |
|  | Title: Director |
| **J.P. MORGAN SECURITIES LLC** | **J.P. MORGAN SECURITIES LLC** |
| By: | /s/ David Ke |
|  | Name: David Ke |
|  | Title: Managing Director |
| **GOLDMAN SACHS & CO. LLC** | **GOLDMAN SACHS & CO. LLC** |
| By: | /s/ Lyla Bibi Maduri |
|  | Name: Lyla Bibi Maduri |
|  | Title: Managing Director |
| **CITIGROUP GLOBAL MARKETS INC.** | **CITIGROUP GLOBAL MARKETS INC.** |
| By: | /s/ Tai Hah |
|  | Name: Tai Hah |
|  | Title: Global Head of MedTech |

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*[Signature Page to Underwriters' Acceleration Request]*