# EDGAR Filing Document

**Accession Number:** 0001773195
**File Stem:** 0001999371-25-007159
**Filing Date:** 2025-6
**Character Count:** 11117
**Document Hash:** 2a79989a325cf461d9d85ed82189db97
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001999371-25-007159.hdr.sgml**: 20250604

**ACCESSION NUMBER**: 0001999371-25-007159

**CONFORMED SUBMISSION TYPE**: SCHEDULE 13G

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250604

**DATE AS OF CHANGE**: 20250604

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Lexeo Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001907108
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 854012572
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-94231
- **FILM NUMBER:** 251023088

**BUSINESS ADDRESS:**
- **STREET 1:** 345 PARK AVENUE SOUTH
- **STREET 2:** FLOOR 6
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10010
- **BUSINESS PHONE:** (212) 547-9879

**MAIL ADDRESS:**
- **STREET 1:** 345 PARK AVENUE SOUTH
- **STREET 2:** FLOOR 6
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10010
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Affinity Asset Advisors, LLC
- **CENTRAL INDEX KEY:** 0001773195

**ORGANIZATION NAME:**
- **EIN:** 821567490
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G

**BUSINESS ADDRESS:**
- **STREET 1:** 450 PARK AVENUE
- **STREET 2:** SUITE 1403
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022
- **BUSINESS PHONE:** 917-826-4533

**MAIL ADDRESS:**
- **STREET 1:** 450 PARK AVENUE
- **STREET 2:** SUITE 1403
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## SCHEDULE 13G

### Under the Securities Exchange Act of 1934

**Issuer:** Lexeo Therapeutics, Inc.

**Title of Class of Securities:** Common Stock, par value $0.0001 per share

**CUSIP Number:** 52886X107

**Date of Event Which Requires Filing of this Statement:** 05/28/2025

**Check the appropriate box to designate the rule pursuant to which this Schedule is filed:**

- [ ] Rule 13d-1(b)

- [x] Rule 13d-1(c)

- [ ] Rule 13d-1(d)

---

| 1. | Names of Reporting Persons<br>Affinity Healthcare Fund, LP | Names of Reporting Persons<br>Affinity Healthcare Fund, LP |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>4252005.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>4252005.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>4252005.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>4252005.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>7.75% | Percent of Class Represented by Amount in Row (9)<br>7.75% |
| 12. | Type of Reporting Person (See Instructions)<br>PN | Type of Reporting Person (See Instructions)<br>PN |

---

| 1. | Names of Reporting Persons<br>Affinity Asset Advisors, LLC | Names of Reporting Persons<br>Affinity Asset Advisors, LLC |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>4252005.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>4252005.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>4252005.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>4252005.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>7.75% | Percent of Class Represented by Amount in Row (9)<br>7.75% |
| 12. | Type of Reporting Person (See Instructions)<br>IA | Type of Reporting Person (See Instructions)<br>IA |

---

**Item 1(a). Name of Issuer:**
Lexeo Therapeutics, Inc.

**Item 1(b). Address of Issuer's Principal Executive Offices:**
345 Park Avenue South, Floor 6, New York, NY 10010

**Item 2(a). Name of Person Filing:**
Affinity Healthcare Fund, LP
Affinity Asset Advisors, LLC

**Item 2(b). Address of Principal Business Office:**
450 Park Avenue
Suite 1403
New York, NY 10022

**Item 2(c). Citizenship:**
Affinity Healthcare Fund, LP and Affinity Asset Advisors, LLC - Delaware

**Item 2(d). Title of Class of Securities:**
Common Stock, par value $0.0001 per share

**Item 2(e). CUSIP Number:**
52886X107

**Item 3. If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:**

(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d) [ ] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).

(e) [ ] An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);

(f) [ ] An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);

(g) [ ] A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j) [ ] A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), if filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:

(k) [ ] Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).

**Item 4. Ownership:**

**(a) Amount beneficially owned:**

Affinity Asset Advisors, LLC (the "Advisor") is the investment manager of Affinity Healthcare Fund, LP (the "Fund") and exercises investment discretion with regard to the securities reported herein.  As of June 4, 2025, the Fund beneficially owned an aggregate of 4,252,005 shares of Common Stock of the Issuer, including warrants to purchase 867,302 shares of Common Stock within the next sixty (60) days, or 7.75% of the outstanding shares of Common Stock of the Issuer, and the Advisor may be deemed to be the beneficial owner of such 4,252,005 shares of Common Stock of the Issuer owned by the Fund by virtue of its position as investment manager of the Fund.  The Fund and the Advisor have the shared power to vote or to direct the vote and to dispose or direct the disposition of 4,252,005 shares of Common Stock of the Issuer.

**(b) Percent of class:**

The percentage set forth in the preceding paragraph and in Row 11 of the cover page for each reporting person is based on 54,854,419 shares of Common Stock of the Issuer outstanding as of May 28, 2025 comprised of (a) the 33,196,997 shares of Common Stock of the Issuer outstanding as of May 12, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 15, 2025, (b) the 20,790,120 shares of Common Stock of the Issuer issued in connection with a private placement by the Issuer on May 28, 2025 as set forth in the Issuer's Current Report on Form 8-K filed with the Securities and Exchange Commission on May 27, 2025 and (c) the 867,302 shares of Common Stock of the Issuer issuable to the Fund upon exercise of Common Warrants of the Issuer sold to the Fund in such private placement.

**(c) Number of shares as to which the person has:**

**(i) Sole power to vote or to direct the vote:**

Affinity Healthcare Fund, LP - 0
Affinity Asset Advisors, LLC - 0

**(ii) Shared power to vote or to direct the vote:**

Affinity Healthcare Fund, LP - 4,252,005
Affinity Asset Advisors, LLC - 4,252,005

**(iii) Sole power to dispose or to direct the disposition of:**

Affinity Healthcare Fund, LP - 0
Affinity Asset Advisors, LLC - 0

**(iv) Shared power to dispose or to direct the disposition of:**

Affinity Healthcare Fund, LP - 4,252,005
Affinity Asset Advisors, LLC - 4,252,005

**Item 5. Ownership of Five Percent or Less of a Class.**

[x] If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following.

**Item 6. Ownership of More than 5 Percent on Behalf of Another Person.**

Not Applicable

**Item 7. Identification and Classification of the Subsidiary**

Not Applicable

**Item 8. Identification and Classification of Members of the Group**

Not Applicable

**Item 9. Notice of Dissolution of Group**

Not Applicable

**Item 10. Certification:**

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

### SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Affinity Healthcare Fund, LP**

**Date:** 06/04/2025

**By:** /s/ Andrew Weinstein

**Name & Title:** Andrew Weinstein

**Affinity Asset Advisors, LLC**

**Date:** 06/04/2025

**By:** /s/ Andrew Weinstein

**Name & Title:** Andrew Weinstein