# EDGAR Filing Document

**Accession Number:** 0001734005
**File Stem:** 0001213900-23-002957
**Filing Date:** 2023-1
**Character Count:** 3000
**Document Hash:** 5c71fbd8b876a5e26cb26333504760c9
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-23-002957.hdr.sgml**: 20230216

**ACCESSION NUMBER**: 0001213900-23-002957

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230117

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Aptorum Group Ltd
- **CENTRAL INDEX KEY:** 0001734005
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 17 HANOVER SQUARE
- **CITY:** LONDON
- **STATE:** X0
- **ZIP:** W1S 1BN
- **BUSINESS PHONE:** 852 3953 7700

**MAIL ADDRESS:**
- **STREET 1:** 17 HANOVER SQUARE
- **CITY:** LONDON
- **STATE:** X0
- **ZIP:** W1S 1BN

**Aptorum Group Limited**

**17 Hanover Square**

**London W1S 1BN, United Kingdom**

**+44 20 80929299**

***VIA EDGAR***

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549

January 17, 2023

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| | |
|:---|:---|
| **Re:** | **Aptorum Group Limited** |
|  | **Registration Statement on Form F-3** |
|  | **Initially Filed on December 19, 2022** |
|  | **File No. 333-268873** |

---

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Aptorum Group Limited (the "Registrant") hereby requests acceleration of effectiveness of the above referenced Registration Statement so that it will become effective at 4:30 p.m. ET on Thursday, January 19, 2023, or as soon thereafter as practicable on such date, or at such other time as the Company or its counsel, Hunter Taubman Fischer & Li LLC ("HTFL"), request by telephone that such Registration Statement be declared effective.

Please note that we acknowledge the following:

● should the U.S. Securities and Exchange Commission (the "**Commission**") or the staff, acting pursuant to delegated authority, declare the filing effective, it does not foreclose the Commission from taking any action with respect to the filing;

● the action of the Commission or the staff, acting pursuant to delegated authority, in declaring the filing effective, does not relieve the Registrant from its full responsibility for the adequacy and accuracy of the disclosure in the filing; and

● the Registrant may not assert staff comments and the declaration of effectiveness as a defense in any proceeding initiated by the Commission or any person under the federal securities laws of the United States.

Please contact Rachael Schmierer of HTFL, counsel to the Company, at (212) 530-2210 or rschmierer@htflawyers.com, as soon as the Registration Statement has been declared effective, or if you have any other questions or concerns regarding this matter.

---

| | |
|:---|:---|
| Sincerely, | Sincerely, |
| By: | */s/ Darren Lui* |
| Name: | Darren Lui |
| Title: | Chief Executive Officer |

---

cc: Louis Taubman, Esq.

Hunter Taubman Fischer & Li LLC