# EDGAR Filing Document

**Accession Number:** 0001039803
**File Stem:** 0000910472-26-004815
**Filing Date:** 2026-3
**Character Count:** 55456
**Document Hash:** 9032e5254e417e1d410567cb92c19b72
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000910472-26-004815.hdr.sgml**: 20260331

**ACCESSION NUMBER**: 0000910472-26-004815

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20260131

**FILED AS OF DATE**: 20260331

**DATE AS OF CHANGE**: 20260331

**PERIOD START**: 20260731

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ProFunds
- **CENTRAL INDEX KEY:** 0001039803

**ORGANIZATION NAME:**
- **EIN:** 522035197
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-08239
- **FILM NUMBER:** 26817508

**BUSINESS ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814
- **BUSINESS PHONE:** 2404976428

**MAIL ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PROFUNDS
- **DATE OF NAME CHANGE:** 19970521

## Series and Classes Contracts Data

### BIOTECHNOLOGY ULTRASECTOR PROFUND (Series ID: S000003107)

| Class ID   | Class Name                                       | Ticker Symbol   |
|:---|:---|:---|
| C000008429 | BIOTECHNOLOGY ULTRASECTOR PROFUND INVESTOR CLASS | BIPIX           |
| C000008430 | BIOTECHNOLOGY ULTRASECTOR PROFUND SERVICE CLASS  | BIPSX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ProFunds

- **b. Investment Company Act file number:** 811-08239

- **c. CIK number of Registrant:** 0001039803

- **d. LEI of Registrant:** 549300HM4OOUYSE5DP77

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 7272 Wisconsin Avenue

  - **City:** Bethesda

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 20814

  - **Telephone number:** 240-497-6400

**Item A.2. Information about the Series.**

- **a. Name of Series:** BIOTECHNOLOGY ULTRASECTOR PROFUND

- **b. EDGAR series identifier (if any):** S000003107

- **c. LEI of Series:** ZWFZRAZNVXWXUXSEEF10

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-07-31

- **b. Date as of which information is reported:** 2026-01-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $324712895.48

**Total Liabilities:** $147340110.60

**Net Assets:** $177372784.88

**Cash Not Reported:** $203.56

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000008429 | 13.54%               | -1.42%               | 2.93%                |
| Class ID C000008430 | 13.45%               | -1.50%               | 2.84%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $517570.36               | $5649248.81                                |
| Month 2  | $-56590.11               | $242409.56                                 |
| Month 3  | $635991.83               | $2346426.55                                |

**Designated Index Information**

- **Index Name:** Dow Jones U.S. Biotechnology Index

- **Index Identifier:** DJUSBT

### Schedule of Portfolio Investments

| Name                                | Title                                         | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Adma Biologics Inc                  | ADMA Biologics, Inc.                          | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     81625 | NS      | $1412112.50   | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Absci Corp.                         | Absci Corporation                             | CUSIP: 00091E109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     57421 | NS      | $171688.79    | 0.10%             |  |  |  | No            |                  1 | On Loan: —       |
| AbbVie Inc.                         | AbbVie, Inc.                                  | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |      7243 | NS      | $1615261.43   | 0.91%             |  |  |  | No            |                  1 | On Loan: No      |
| Acadia Pharmaceuticals Inc          | ACADIA Pharmaceuticals, Inc.                  | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |     55582 | NS      | $1396775.66   | 0.79%             |  |  |  | No            |                  1 | On Loan: No      |
| Invivyd Inc                         | Invivyd, Inc.                                 | CUSIP: 00534A102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     79776 | NS      | $138810.24    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc              | Spyre Therapeutics, Inc.                      | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |     14973 | NS      | $478836.54    | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Agios Pharmaceuticals Inc           | Agios Pharmaceuticals, Inc.                   | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     30134 | NS      | $826876.96    | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Akebia Therapeutics Inc.            | Akebia Therapeutics, Inc.                     | CUSIP: 00972D105<br>LEI: 549300CBQEHMKEEGNX42 | Long             | EC               | CORP              | US        |    139787 | NS      | $197099.67    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc.        | Alnylam Pharmaceuticals, Inc.                 | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |      4032 | NS      | $1363057.92   | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc.                      | Altimmune, Inc.                               | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |     54882 | NS      | $307339.20    | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc.                          | Amgen, Inc.                                   | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |      5171 | NS      | $1767861.48   | 1.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Amicus Therapeutics Inc.            | Amicus Therapeutics, Inc.                     | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |    138235 | NS      | $1975378.15   | 1.11%             |  |  |  | No            |                  1 | On Loan: No      |
| AnaptysBio Inc.                     | AnaptysBio, Inc.                              | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |      9899 | NS      | $469311.59    | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp.          | Anavex Life Sciences Corporation              | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |     43818 | NS      | $205944.60    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon Inc                         | Annexon, Inc.                                 | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     39710 | NS      | $247790.40    | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals Inc         | Apellis Pharmaceuticals, Inc.                 | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |     48067 | NS      | $1085352.86   | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc.            | Apogee Therapeutics, Inc.                     | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13630 | NS      | $892901.30    | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp.             | Arbutus Biopharma Corporation                 | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | US        |     32809 | NS      | $135501.17    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcellx Inc                         | Arcellx, Inc.                                 | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     19488 | NS      | $1331225.28   | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardelyx Inc                         | Ardelyx, Inc.                                 | CUSIP: 039697107<br>LEI: 549300F542QR4SXHCY32 | Long             | EC               | CORP              | US        |    109395 | NS      | $841247.55    | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcus Biosciences Inc.              | Arcus Biosciences, Inc.                       | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     26052 | NS      | $548134.08    | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcutis Biotherapeutics Inc.        | Arcutis Biotherapeutics, Inc.                 | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     48238 | NS      | $1223798.06   | 0.69%             |  |  |  | No            |                  1 | On Loan: No      |
| ArriVent BioPharma Inc.             | ArriVent Biopharma, Inc.                      | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8096 | NS      | $182079.04    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Arrowhead Pharmaceuticals Inc       | Arrowhead Pharmaceuticals, Inc.               | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |     23681 | NS      | $1641803.73   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Avidity Biosciences Inc.            | Avidity Biosciences, Inc.                     | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22857 | NS      | $1658732.49   | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicara Therapeutics Inc.            | Bicara Therapeutics, Inc.                     | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     16749 | NS      | $281383.20    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc.              | Beam Therapeutics, Inc.                       | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49582 | NS      | $1369454.84   | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| BioCryst Pharmaceuticals  Inc.      | BioCryst Pharmaceuticals, Inc.                | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    107248 | NS      | $705691.84    | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Biomarin Pharmaceutical Inc.        | BioMarin Pharmaceutical, Inc.                 | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |     30370 | NS      | $1717119.80   | 0.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                          | Biogen, Inc.                                  | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |      9185 | NS      | $1652289.65   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | BIPIX_SPSIBI_GOLDMAN                          | CUSIP: N/A<br>LEI: N/A                        | Long             | DE               |  | US        |      6864 | OU      | $-1830393.12  | -1.03%            |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | BIPIX_SPSIBI_GOLDMAN                          | CUSIP: N/A<br>LEI: N/A                        | Short            | DE               |  | US        |       -30 | OU      | $4618.62      | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | BIPIX_SPSIBI_UB                               | CUSIP: N/A<br>LEI: N/A                        | Long             | DE               |  | US        |      7243 | OU      | $-1927428.39  | -1.09%            |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | BIPIX_SPSIBI_UB                               | CUSIP: N/A<br>LEI: N/A                        | Short            | DE               |  | US        |      -590 | OU      | $45137.82     | 0.03%             |  |  |  | No            |                  2 | On Loan: No      |
| Bridgebio Pharma Inc                | Bridgebio Pharma, Inc.                        | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |     22433 | NS      | $1733397.91   | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Caredx Inc                          | CareDx, Inc.                                  | CUSIP: 14167L103<br>LEI: 549300NQOFKL9NON0U06 | Long             | EC               | CORP              | US        |     25549 | NS      | $525031.95    | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc.       | Catalyst Pharmaceuticals, Inc.                | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |     43464 | NS      | $1056175.20   | 0.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Celcuity Inc.                       | Celcuity, Inc.                                | CUSIP: 15102K100<br>LEI: 25490070W7UU7W2SEY87 | Long             | EC               | CORP              | US        |     16016 | NS      | $1752470.72   | 0.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc.           | Celldex Therapeutics, Inc.                    | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |     32024 | NS      | $787790.40    | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| CG Oncology Inc.                    | CG oncology, Inc.                             | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     29731 | NS      | $1547498.55   | 0.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences Inc.             | Cogent Biosciences, Inc.                      | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     31144 | NS      | $1118381.04   | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Compass Therapeutics Inc            | Compass Therapeutics, Inc.                    | CUSIP: 20454B104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     42540 | NS      | $272256.00    | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Corvus Pharmaceuticals Inc          | Corvus Pharmaceuticals, Inc.                  | CUSIP: 221015100<br>LEI: 549300I3AVJ8F75NCX65 | Long             | EC               | CORP              | US        |     27957 | NS      | $578709.90    | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc           | Cullinan Therapeutics, Inc.                   | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     17290 | NS      | $206788.40    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                    | Cytokinetics, Inc.                            | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |     27039 | NS      | $1708594.41   | 0.96%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytomx Therapeutics Inc             | CytomX Therapeutics, Inc.                     | CUSIP: 23284F105<br>LEI: 5493004VW2FW0QLL3345 | Long             | EC               | CORP              | US        |     76698 | NS      | $436411.62    | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc.     | Day One Biopharmaceuticals, Inc.              | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     44017 | NS      | $491229.72    | 0.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc             | Denali Therapeutics, Inc.                     | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |     53705 | NS      | $1167546.70   | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc           | Dianthus Therapeutics, Inc.                   | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |     16225 | NS      | $866252.75    | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Disc Medicine Inc                   | Disc Medicine, Inc.                           | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10119 | NS      | $782401.08    | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | Eli Lilly & Company                           | CUSIP: N/A<br>LEI: N/A                        | Long             |  | CORP              | US        |      9511 | NS      | $5991.93      | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Dynavax Technologies Corp.          | Dynavax Technologies Corporation              | CUSIP: 268158201<br>LEI: 549300T5URIXWDILX594 | Long             | EC               | CORP              | US        |     51561 | NS      | $798422.09    | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Dyne Therapeutics Inc.              | Dyne Therapeutics, Inc.                       | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     65698 | NS      | $1175337.22   | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Emergent Biosolutions Inc           | Emergent BioSolutions, Inc.                   | CUSIP: 29089Q105<br>LEI: 549300YW6TUOX8BE5103 | Long             | EC               | CORP              | US        |     24956 | NS      | $283001.04    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Erasca Inc                          | Erasca, Inc.                                  | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     36680 | NS      | $385506.80    | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corporation          | Exact Sciences Corporation                    | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |     16107 | NS      | $1648390.38   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Exelixis, Inc.                      | Exelixis, Inc.                                | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |     39710 | NS      | $1642405.60   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| 4D Molecular Therapeutics Inc       | 4D Molecular Therapeutics, Inc.               | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23384 | NS      | $207182.24    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Geron Corp.                         | Geron Corporation                             | CUSIP: 374163103<br>LEI: 549300T282D7Z2YESL90 | Long             | EC               | CORP              | US        |    230413 | NS      | $315665.81    | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc.                | Gilead Sciences, Inc.                         | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |     13441 | NS      | $1907949.95   | 1.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Gossamer Bio Inc                    | Gossamer Bio, Inc.                            | CUSIP: 38341P102<br>LEI: 549300ZOC0N2W6PSFR58 | Long             | EC               | CORP              | US        |     87693 | NS      | $199940.04    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| GRAIL Inc                           | GRAIL, Inc.                                   | CUSIP: 384747101<br>LEI: 2549009XSNESW3VE8024 | Long             | EC               | CORP              | US        |     17181 | NS      | $1680645.42   | 0.95%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc           | Halozyme Therapeutics, Inc.                   | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |     26032 | NS      | $1866754.72   | 1.05%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEAYA Biosciences Inc.             | Ideaya Biosciences, Inc.                      | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |     35425 | NS      | $1140330.75   | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Immuneering Corp.                   | Immuneering Corp.                             | CUSIP: 45254E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     36653 | NS      | $169703.39    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| ImmunityBio Inc                     | ImmunityBio, Inc.                             | CUSIP: 45256X103<br>LEI: 529900J9XLBR4HFL4B83 | Long             | EC               | CORP              | US        |    170262 | NS      | $1064137.50   | 0.60%             |  |  |  | No            |                  1 | On Loan: —       |
| Immunome Inc                        | Immunome, Inc.                                | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     31790 | NS      | $782669.80    | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant Inc                      | Immunovant, Inc.                              | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     37102 | NS      | $964652.00    | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corporation.                 | Incyte Corporation                            | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |     17136 | NS      | $1714799.52   | 0.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Inhibrx Biosciences  Inc.           | Inhibrx Biosciences, Inc.                     | CUSIP: 45720N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2406 | NS      | $183505.62    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                          | Insmed, Inc.                                  | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |      8590 | NS      | $1347513.30   | 0.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc           | Intellia Therapeutics, Inc.                   | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |     60394 | NS      | $794181.10    | 0.45%             |  |  |  | No            |                  1 | On Loan: —       |
| Ionis Pharmaceuticals, Inc.         | Ionis Pharmaceuticals, Inc.                   | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |     20741 | NS      | $1714658.47   | 0.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics Inc         | Iovance Biotherapeutics, Inc.                 | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |    198050 | NS      | $505027.50    | 0.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Ironwood Pharmaceuticals, Inc.      | Ironwood Pharmaceuticals, Inc.                | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |     18178 | NS      | $88890.42     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Janux Therapeutics Inc              | Janux Therapeutics, Inc.                      | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49130 | NS      | $673572.30    | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals Inc.       | KalVista Pharmaceuticals, Inc.                | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |     18388 | NS      | $287036.68    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Keros Therapeutics Inc.             | Keros Therapeutics, Inc.                      | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8488 | NS      | $152020.08    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Kodiak Sciences Inc                 | Kodiak Sciences, Inc.                         | CUSIP: 50015M109<br>LEI: 254900IXI5NI8C9OQE24 | Long             | EC               | CORP              | US        |     16686 | NS      | $379940.22    | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech Inc                 | Krystal Biotech, Inc.                         | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |      6803 | NS      | $1899669.72   | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology Inc.                  | Kura Oncology, Inc.                           | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |     52534 | NS      | $426576.08    | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc             | Kymera Therapeutics, Inc.                     | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     16443 | NS      | $1195241.67   | 0.67%             |  |  |  | No            |                  1 | On Loan: No      |
| Lexeo Therapeutics Inc              | Lexeo Therapeutics, Inc.                      | CUSIP: 52886X107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     28639 | NS      | $212214.99    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Madrigal Pharmaceuticals Inc        | Madrigal Pharmaceuticals, Inc.                | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |      2952 | NS      | $1444443.12   | 0.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Mannkind Corporation                | MannKind Corporation                          | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |    126848 | NS      | $733181.44    | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| MiMedx Group Inc.                   | MiMedx Group, Inc.                            | CUSIP: 602496101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     19429 | NS      | $99282.19     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Mineralys Therapeutics Inc.         | Mineralys Therapeutics, Inc.                  | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     35860 | NS      | $1107715.40   | 0.62%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharmaceuticals Inc.          | Mirum Pharmaceuticals, Inc.                   | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |     20449 | NS      | $2110745.78   | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                         | Moderna, Inc.                                 | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |     56187 | NS      | $2476161.09   | 1.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics Inc         | Monte Rosa Therapeutics, Inc.                 | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     18906 | NS      | $387951.12    | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Myriad Genetics Inc.                | Myriad Genetics, Inc.                         | CUSIP: 62855J104<br>LEI: 52990044IHUOUMETT163 | Long             | EC               | CORP              | US        |     41835 | NS      | $235112.70    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc.                         | Natera, Inc.                                  | CUSIP: 632307104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6996 | NS      | $1617055.44   | 0.91%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc          | Neurocrine Biosciences, Inc.                  | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |     10479 | NS      | $1425772.74   | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Novavax Inc                         | Novavax, Inc.                                 | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |     92370 | NS      | $817012.65    | 0.46%             |  |  |  | No            |                  1 | On Loan: —       |
| Nuvalent Inc                        | Nuvalent, Inc.                                | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12881 | NS      | $1325326.09   | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics Inc.             | Nurix Therapeutics, Inc.                      | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     25375 | NS      | $419195.00    | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Olema Pharmaceuticals Inc.          | Olema Pharmaceuticals, Inc.                   | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12617 | NS      | $324509.24    | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC Pharmaceuticals Inc.           | ORIC Pharmaceuticals, Inc.                    | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |     49671 | NS      | $509624.46    | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics Inc              | Oruka Therapeutics, Inc.                      | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |     10789 | NS      | $369307.47    | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| PTC Therapeutics, Inc.              | PTC Therapeutics, Inc.                        | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |     22009 | NS      | $1662339.77   | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Palvella Therapeutics Inc.          | Palvella Therapeutics, Inc.                   | CUSIP: 697947109<br>LEI: 254900AJDH8PAOOI5T33 | Long             | EC               | CORP              | US        |      4413 | NS      | $338432.97    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc      | Praxis Precision Medicines, Inc.              | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6235 | NS      | $1957790.00   | 1.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Precigen Inc                        | Precigen, Inc.                                | CUSIP: 74017N105<br>LEI: 549300XCWNQU35K64G19 | Long             | EC               | CORP              | US        |    104906 | NS      | $471027.94    | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Prime Medicine Inc                  | Prime Medicine, Inc.                          | CUSIP: 74168J101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     52624 | NS      | $200497.44    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc        | Protagonist Therapeutics, Inc.                | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     17847 | NS      | $1459884.60   | 0.82%             |  |  |  | No            |                  1 | On Loan: No      |
| RAPT Therapeutics Inc.              | RAPT Therapeutics, Inc.                       | CUSIP: 75382E208<br>LEI: 549300MB473BIU78ES48 | Long             | EC               | CORP              | US        |      9247 | NS      | $533366.96    | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Recursion Pharmaceuticals Inc       | Recursion Pharmaceuticals, Inc.               | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    271602 | NS      | $1138012.38   | 0.64%             |  |  |  | No            |                  1 | On Loan: —       |
| Regeneron Pharmaceuticals, Inc.     | Regeneron Pharmaceuticals, Inc.               | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |      2246 | NS      | $1665296.70   | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Regenxbio Inc.                      | REGENXBIO, Inc.                               | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |     16596 | NS      | $185211.36    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc              | Relay Therapeutics, Inc.                      | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     54319 | NS      | $416083.54    | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc                 | Replimune Group, Inc.                         | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |     39527 | NS      | $277874.81    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Revolution Medicines Inc            | Revolution Medicines, Inc.                    | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |     20967 | NS      | $2032750.65   | 1.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                        | Rezolute, Inc.                                | CUSIP: 76200L309<br>LEI: 549300T05L48T72P2G08 | Long             | EC               | CORP              | US        |     39079 | NS      | $130523.86    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc          | Rhythm Pharmaceuticals, Inc.                  | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |     15566 | NS      | $1595826.32   | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Rigel Pharmaceuticals Inc.          | Rigel Pharmaceuticals, Inc.                   | CUSIP: 766559702<br>LEI: 529900KPTNUS5J8K9K66 | Long             | EC               | CORP              | US        |     12082 | NS      | $421178.52    | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc              | Sana Biotechnology, Inc.                      | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     76860 | NS      | $340489.80    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics Inc            | Sarepta Therapeutics, Inc.                    | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |     54739 | NS      | $1113391.26   | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara Inc                          | Savara, Inc.                                  | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |     25191 | NS      | $136031.40    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp.          | Scholar Rock Holding Corporation              | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |     36201 | NS      | $1605152.34   | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| ARS Pharmaceuticals Inc             | ARS Pharmaceuticals, Inc.                     | CUSIP: 82835W108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     32398 | NS      | $323656.02    | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Sionna Therapeutics Inc.            | Sionna Therapeutics, Inc.                     | CUSIP: 829401108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6922 | NS      | $292523.72    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Soleno Therapeutics Inc             | Soleno Therapeutics, Inc.                     | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |     26800 | NS      | $1033408.00   | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc              | Stoke Therapeutics, Inc.                      | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |     25285 | NS      | $767146.90    | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Summit Therapeutics Inc.            | Summit Therapeutics, Inc.                     | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     80686 | NS      | $1168333.28   | 0.66%             |  |  |  | No            |                  1 | On Loan: —       |
| Syndax Pharmaceuticals Inc.         | Syndax Pharmaceuticals, Inc.                  | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |     45401 | NS      | $922094.31    | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics Inc.             | Tango Therapeutics, Inc.                      | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     63527 | NS      | $737548.47    | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Taysha Gene Therapies Inc.          | Taysha Gene Therapies, Inc.                   | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96659 | NS      | $435932.09    | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| TG Therapeutics Inc                 | TG Therapeutics, Inc.                         | CUSIP: 88322Q108<br>LEI: 529900X21UKABN9NJ529 | Long             | EC               | CORP              | US        |     53297 | NS      | $1568530.71   | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Travere Therapeutics Inc            | Travere Therapeutics, Inc.                    | CUSIP: 89422G107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     47437 | NS      | $1474816.33   | 0.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corporation        | Twist Bioscience Corporation                  | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |     32028 | NS      | $1315389.96   | 0.74%             |  |  |  | No            |                  1 | On Loan: No      |
| Tyra Biosciences Inc                | Tyra Biosciences, Inc.                        | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4333 | NS      | $133543.06    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceuticals Inc      | Ultragenyx Pharmaceutical, Inc.               | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |     44032 | NS      | $1059850.24   | 0.60%             |  |  |  | No            |                  1 | On Loan: No      |
| United Therapeutics Corporation     | United Therapeutics Corporation               | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |      3364 | NS      | $1579364.36   | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Upstream Bio Inc                    | Upstream Bio, Inc.                            | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10845 | NS      | $337062.60    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Vaxcyte Inc                         | Vaxcyte, Inc.                                 | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |     37500 | NS      | $2008875.00   | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Verastem Inc                        | Verastem, Inc.                                | CUSIP: 92337C203<br>LEI: 549300IY0EFBIU8NQC81 | Long             | EC               | CORP              | US        |     36258 | NS      | $221173.80    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                        | Veracyte, Inc.                                | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |     24212 | NS      | $921992.96    | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| Vera Therapeutics Inc.              | Vera Therapeutics, Inc.                       | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     24064 | NS      | $1041008.64   | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| Vericel Corporation                 | Vericel Corporation                           | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |     21193 | NS      | $762524.14    | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Incorporated | Vertex Pharmaceuticals, Inc.                  | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |      3668 | NS      | $1723593.20   | 0.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Viking Therapeutics Inc.            | Viking Therapeutics, Inc.                     | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |     43455 | NS      | $1261933.20   | 0.71%             |  |  |  | No            |                  1 | On Loan: No      |
| VIR Biotechnology Inc               | Vir Biotechnology, Inc.                       | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     37500 | NS      | $279000.00    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Viridian Therapeutics Inc           | Viridian Therapeutics, Inc.                   | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |     27964 | NS      | $922812.00    | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor Inc                          | Xencor, Inc.                                  | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |     27403 | NS      | $331302.27    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| AGPXX                               | Invesco Government & Agency Portfolio         | CUSIP: 825252885<br>LEI: N/A                  | Long             | STIV             | RF                | US        |   4141972 | NS      | $4141971.50   | 2.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes PLC                        | Alkermes plc                                  | CUSIP: G01767105<br>LEI: N/A                  | Long             | EC               | CORP              | IE        |     56984 | NS      | $1931187.76   | 1.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                        | Biohaven Ltd.                                 | CUSIP: G1110E107<br>LEI: N/A                  | Long             | EC               | CORP              | VG        |     58678 | NS      | $694160.74    | 0.39%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corporation PLC            | Prothena Corp plc                             | CUSIP: G72800108<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | IE        |     23144 | NS      | $203898.64    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                | Roivant Sciences Ltd.                         | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | US        |     80577 | NS      | $1742074.74   | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| CRISPR Therapeutics AG              | CRISPR Therapeutics A.G.                      | CUSIP: H17182108<br>LEI: 506700O6IRRIQLT3W370 | Long             | EC               | CORP              | CH        |     28319 | NS      | $1414817.24   | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | HSBC SECURITIES (USA), INC.  3.55 , 2/02/2026 | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |  10728000 | PA      | $10728000.00  | 6.05%             |  |  |  | No            |                  2 | On Loan: No      |
| Uniqure N.V.                        | uniQure N.V.                                  | CUSIP: N90064101<br>LEI: 724500RPCTZLFYJZ3S98 | Long             | EC               | CORP              | NL        |     46240 | NS      | $1050572.80   | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | NATWEST MARKETS PLC  3.53 , 2/02/2026         | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |  11158000 | PA      | $11158000.00  | 6.29%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | ROYAL BANK OF CANADA  3.45 , 2/02/2026        | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |   6007000 | PA      | $6007000.00   | 3.39%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | SOCIETE' GENERALE  3.55 , 2/02/2026           | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |  13948000 | PA      | $13948000.00  | 7.86%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | UMB FINANCIAL CORP. B 3.4 , 2/02/2026         | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |   5979000 | PA      | $5979000.00   | 3.37%             |  |  |  | No            |                  2 | On Loan: No      |

### Signature

**Date Signed:** 2026-02-02

**Name of Applicant:** Biotechnology UltraSector ProFund

**Signature:** Rebecca Colvin

**Name of Signer:** Rebecca Colvin

**Title:** Treasurer and Principal Financial Officer