# EDGAR Filing Document

**Accession Number:** 0000836487
**File Stem:** 0001752724-23-041541
**Filing Date:** 2023-2
**Character Count:** 21563
**Document Hash:** 2a178ecef4cf5d85c9f4e45c22423021
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-23-041541.hdr.sgml**: 20230227

**ACCESSION NUMBER**: 0001752724-23-041541

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230227

**DATE AS OF CHANGE**: 20230227

**PERIOD START**: 20221231

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MORGAN STANLEY INSTITUTIONAL FUND INC
- **CENTRAL INDEX KEY:** 0000836487
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** MD
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-05624
- **FILM NUMBER:** 23671524

**BUSINESS ADDRESS:**
- **STREET 1:** 522 FIFTH AVENUE
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10036
- **BUSINESS PHONE:** 800-548-7786

**MAIL ADDRESS:**
- **STREET 1:** 522 FIFTH AVENUE
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10036

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MORGAN STANLEY DEAN WITTER INSTITUTIONAL FUND INC
- **DATE OF NAME CHANGE:** 19990329

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MORGAN STANLEY INSTITUTIONAL FUND INC
- **DATE OF NAME CHANGE:** 19920703

## Series and Classes Contracts Data

### Vitality Portfolio (Series ID: S000074797)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000233002 | Class I      |  |
| C000233003 | Class A      |  |
| C000233004 | Class C      |  |
| C000233005 | Class IS     |  |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** MORGAN STANLEY INSTITUTIONAL FUND INC

- **b. Investment Company Act file number:** 811-05624

- **c. CIK number of Registrant:** 0000836487

- **d. LEI of Registrant:** 54930067DYRSUSGS4E97

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 522 FIFTH AVENUE

  - **City:** NEW YORK

  - **State:** NY

  - **Foreign country:** US

  - **Zip / Postal Code:** 10036

  - **Telephone number:** 800-548-7786

**Item A.2. Information about the Series.**

- **a. Name of Series:** Vitality Portfolio

- **b. EDGAR series identifier (if any):** S000074797

- **c. LEI of Series:** 549300V9WWJX6LPH4Y61

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2022-12-31

- **b. Date as of which information is reported:** 2022-12-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $2143235.76

**Total Liabilities:** $159129.27

**Net Assets:** $1984106.49

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000233003 | 4.97%                | 4.74%                | -6.49%               |
| Class ID C000233002 | 4.96%                | 4.72%                | -6.44%               |
| Class ID C000233004 | 4.83%                | 4.77%                | -6.52%               |
| Class ID C000233005 | 4.96%                | 4.72%                | -6.39%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-38576.85               | $135821.38                                 |
| Month 2  | $-200734.73              | $296425.84                                 |
| Month 3  | $0.00                    | $-134311.73                                |

### Schedule of Portfolio Investments

| Name                                               | Title                                                                        | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| GH Research PLC                                    | GH Research PLC                                                              | CUSIP: 000000000<br>LEI: 875500HKJS7QQG6EWH62 | Long             | EC               | CORP              | IE        |       932 | NS      | $9012.44      | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc                                   | 10X Genomics Inc                                                             | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |      2312 | NS      | $84249.28     | 4.25%             |  |  |  | No            |                  1 | On Loan: No      |
| HSBC Securities (USA) Inc.                         | HSBC TRI PARTY   A REPO                                                      | CUSIP: 000000000<br>LEI: CYYGQCGNHMHPSMRL3R97 | Long             | RA               | CORP              | US        |      5872 | PA      | $5871.54      | 0.30%             |  |  |  | No            |                  2 | On Loan: No      |
| Alnylam Pharmaceuticals Inc                        | Alnylam Pharmaceuticals Inc                                                  | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |       355 | NS      | $84365.75     | 4.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc                             | Relay Therapeutics Inc                                                       | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1196 | NS      | $17868.24     | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Inc                         | Vertex Pharmaceuticals Inc                                                   | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |       268 | NS      | $77393.04     | 3.90%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc                             | UnitedHealth Group Inc                                                       | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |       208 | NS      | $110277.44    | 5.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corp                                | Exact Sciences Corp                                                          | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |      1174 | NS      | $58124.74     | 2.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Merrill Lynch, Pierce, Fenner & Smith Incorporated | MERRILL LYNCH TRI PARTY A REPO                                               | CUSIP: 000000000<br>LEI: 8NAV47T0Y26Q87Y0QP81 | Long             | RA               | CORP              | US        |      5872 | PA      | $5871.54      | 0.30%             |  |  |  | No            |                  2 | On Loan: No      |
| agilon health Inc                                  | agilon health Inc                                                            | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2736 | NS      | $44159.04     | 2.23%             |  |  |  | No            |                  1 | On Loan: No      |
| AbCellera Biologics Inc                            | AbCellera Biologics Inc                                                      | CUSIP: 00288U106<br>LEI: 9845000861BC95FF9F73 | Long             | EC               | CORP              | CA        |      1793 | NS      | $18163.09     | 0.92%             |  |  |  | No            |                  1 | On Loan: —       |
| Thermo Fisher Scientific Inc                       | Thermo Fisher Scientific Inc                                                 | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |       191 | NS      | $105181.79    | 5.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Century Therapeutics Inc                           | Century Therapeutics Inc                                                     | CUSIP: 15673T100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1415 | NS      | $7258.95      | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| iRhythm Technologies Inc                           | iRhythm Technologies Inc                                                     | CUSIP: 450056106<br>LEI: 549300FJI72RJGDQS384 | Long             | EC               | CORP              | US        |       111 | NS      | $10397.37     | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc                              | Beam Therapeutics Inc                                                        | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       995 | NS      | $38914.45     | 1.96%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc                          | Intellia Therapeutics Inc                                                    | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |      1153 | NS      | $40228.17     | 2.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Zoetis Inc                                         | Zoetis Inc                                                                   | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |       331 | NS      | $48508.05     | 2.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc                        | Inspire Medical Systems Inc                                                  | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |       315 | NS      | $79342.20     | 4.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc                               | Align Technology Inc                                                         | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |       204 | NS      | $43023.60     | 2.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                                  | Veeva Systems Inc                                                            | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |       252 | NS      | $40667.76     | 2.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                                        | Moderna Inc                                                                  | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |       298 | NS      | $53526.76     | 2.70%             |  |  |  | No            |                  1 | On Loan: No      |
| Morgan Stanley & Co. LLC                           | Morgan Stanley Institutional Liquidity Funds - Treasury Securities Portfolio | CUSIP: 61747C525<br>LEI: 549300OJY9IZ31SGS926 | Long             | STIV             | RF                | US        |     53020 | NS      | $53020.06     | 2.67%             |  |  |  | No            |                  1 | On Loan: No      |
| ATAI Life Sciences NV                              | ATAI Life Sciences NV                                                        | CUSIP: 000000000<br>LEI: 391200Z8UWPJSNBNCA11 | Long             | EC               | CORP              | NL        |      8657 | NS      | $23027.62     | 1.16%             |  |  |  | No            |                  1 | On Loan: —       |
| Illumina Inc                                       | Illumina Inc                                                                 | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |       283 | NS      | $57222.60     | 2.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                                       | Doximity Inc                                                                 | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1315 | NS      | $44131.40     | 2.22%             |  |  |  | No            |                  1 | On Loan: No      |
| SomaLogic Inc                                      | SomaLogic Inc                                                                | CUSIP: 83444K105<br>LEI: 549300D3W3Q8CN30YO25 | Long             | EC               | CORP              | US        |      6954 | NS      | $17454.54     | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health Inc                                | Guardant Health Inc                                                          | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |       880 | NS      | $23936.00     | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Fate Therapeutics Inc                              | Fate Therapeutics Inc                                                        | CUSIP: 31189P102<br>LEI: 549300L14Q4UHOODLA90 | Long             | EC               | CORP              | US        |      1528 | NS      | $15417.52     | 0.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc                             | Intuitive Surgical Inc                                                       | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |       297 | NS      | $78808.95     | 3.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Abbott Laboratories                                | Abbott Laboratories                                                          | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |       310 | NS      | $34034.90     | 1.72%             |  |  |  | No            |                  1 | On Loan: No      |
| ViewRay Inc                                        | ViewRay Inc                                                                  | CUSIP: 92672L107<br>LEI: 5493006XTUBSKFU3W106 | Long             | EC               | CORP              | US        |      9399 | NS      | $42107.52     | 2.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Dexcom Inc                                         | Dexcom Inc                                                                   | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |       697 | NS      | $78928.28     | 3.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Argenx SE                                          | Argenx SE                                                                    | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |       238 | NS      | $90161.54     | 4.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Abcam PLC                                          | Abcam PLC                                                                    | CUSIP: 000380204<br>LEI: 213800B9N83DSNT33F79 | Long             | EC               | CORP              | GB        |      1859 | NS      | $28926.04     | 1.46%             |  |  |  | No            |                  1 | On Loan: No      |
| Schrodinger Inc/United States                      | Schrodinger Inc/United States                                                | CUSIP: 80810D103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1942 | NS      | $36295.98     | 1.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc                                      | Altimmune Inc                                                                | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |      1009 | NS      | $16598.05     | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| Evotec SE                                          | Evotec SE                                                                    | CUSIP: 30050E105<br>LEI: 529900F9KI6OYITO9B12 | Long             | EC               | CORP              | DE        |      3384 | NS      | $27376.56     | 1.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Morgan Stanley & Co. LLC                           | Morgan Stanley Institutional Liquidity Funds - Treasury Securities Portfolio | CUSIP: 61747C525<br>LEI: 549300OJY9IZ31SGS926 | Long             | STIV             | RF                | US        |     63282 | NS      | $63282.17     | 3.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Chewy Inc                                          | Chewy Inc                                                                    | CUSIP: 16679L109<br>LEI: 254900NPQSTG9I422879 | Long             | EC               | CORP              | US        |       982 | NS      | $36412.56     | 1.84%             |  |  |  | No            |                  1 | On Loan: —       |
| Stevanato Group SpA                                | Stevanato Group SpA                                                          | CUSIP: 000000000<br>LEI: 81560033F7E1CD477507 | Long             | EC               | CORP              | IT        |      2617 | NS      | $47027.49     | 2.37%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Inc                   | West Pharmaceutical Services Inc                                             | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |       140 | NS      | $32949.00     | 1.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                                     | Eli Lilly & Co                                                               | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |       286 | NS      | $104630.24    | 5.27%             |  |  |  | No            |                  1 | On Loan: No      |
| 4D Molecular Therapeutics Inc                      | 4D Molecular Therapeutics Inc                                                | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1237 | NS      | $27473.77     | 1.38%             |  |  |  | No            |                  1 | On Loan: No      |
| MaxCyte Inc                                        | MaxCyte Inc                                                                  | CUSIP: 57777K106<br>LEI: 54930053YHXULRFCU991 | Long             | EC               | CORP              | US        |      7901 | NS      | $43139.46     | 2.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Royalty Pharma PLC                                 | Royalty Pharma PLC                                                           | CUSIP: 000000000<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |      1535 | NS      | $60663.20     | 3.06%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEXX Laboratories Inc                             | IDEXX Laboratories Inc                                                       | CUSIP: 45168D104<br>LEI: OGMTXK0LUU1HKV2P0J84 | Long             | EC               | CORP              | US        |        91 | NS      | $37124.36     | 1.87%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2023-01-17

**Name of Applicant:** MORGAN STANLEY INSTITUTIONAL FUND INC

**Signature:** Francis Smith

**Name of Signer:** Francis Smith

**Title:** Principal Financial Officer