# EDGAR Filing Document

**Accession Number:** 0001839948
**File Stem:** 0001104659-25-085653
**Filing Date:** 2025-8
**Character Count:** 18212
**Document Hash:** bdc43cdd79161ca5ffa05b037d39166c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-085653.hdr.sgml**: 20250829

**ACCESSION NUMBER**: 0001104659-25-085653

**CONFORMED SUBMISSION TYPE**: N-PX

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250829

**EFFECTIVENESS DATE**: 20250829

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** TCG Crossover Management, LLC
- **CENTRAL INDEX KEY:** 0001839948

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** N-PX
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-22283
- **FILM NUMBER:** 251280877

**BUSINESS ADDRESS:**
- **STREET 1:** 705 HIGH ST.
- **CITY:** PALO ALTO
- **STATE:** CA
- **ZIP:** 94301
- **BUSINESS PHONE:** 650-924-9424

**MAIL ADDRESS:**
- **STREET 1:** 705 HIGH ST.
- **CITY:** PALO ALTO
- **STATE:** CA
- **ZIP:** 94301

## FORM N-PX
### ANNUAL REPORT OF PROXY VOTING RECORD

## N-PX: Filer Information

**Filer CIK:** 0001839948

**Date of Report:** 06/30/2025

**Are you a Registered Management Investment Company or an Institutional Manager?:** Institutional Manager

**Is this a LIVE or TEST Filing?:** LIVE

**Is this an electronic copy of an official filing submitted in paper format?:** [ ]

### Submission Contact Information
_Not provided in this filing._

### Notification Information
**Notify via Filing Website only?:** [ ]

## N-PX: Cover Page

**Name of reporting person:** TCG Crossover Management, LLC

**Address:** 705 High St., Palo Alto, CA 94301

**Telephone number:** 650-924-9424

**Name of agent for service:** —

**Agent Address:** —, —, — —

**Reporting Period:** Report for the year ended 06/30/2025

**SEC File Number:** 028-22283

**CRD Number (if any):** —

**Other SEC File Number (if any):** —

**LEI (if any):** —

**Report Type (check only one):**

Institutional Manager.

- [x] Institutional Manager Voting Report

- [ ] Institutional Manager Notice Report

- [ ] Institutional Manager Combination Report

Registered Management Investment Company.

- [ ] Fund Voting Report

- [ ] Fund Notice Report

**Do you wish to provide explanatory information pursuant to Special Instruction B.4?:**

- [x] No

- [ ] Yes

**Additional information:** —

## N-PX: Summary - Included Managers

**Number of Included Institutional Managers:** 0

**Included Institutional Managers:** —

## FORM N-PX PROXY VOTING RECORD

| NAME OF ISSUER               | CUSIP     | MEETING DATE   | VOTE DESCRIPTION                                                                                                                                                                                      | VOTE CATEGORY                |   SHARES VOTED |   SHARES ON LOAN | HOW VOTED   |   SHARES VOTED FOR OR AGAINST MANAGEMENT | FOR OR AGAINST MANAGEMENT   | OTHER INFO   |
|:---|:---|:---|:---|:---|---:|---:|:---|---:|:---|:---|
| ADVERUM BIOTECHNOLOGIES INC  | 00773U207 | 06/17/2025     | To approve, on an advisory basis, the compensation of our named executive officers, as disclosed in the proxy statement                                                                               | SECTION 14A SAY-ON-PAY VOTES |        1796482 |                0 | FOR         |                                  1796482 | FOR                         |  |
| AMYLYX PHARMACEUTICALS INC   | 03237H101 | 06/05/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |        5943812 |                0 | FOR         |                                  5943812 | FOR                         |  |
| ASTRIA THERAPEUTICS INC      | 04635X102 | 06/11/2025     | The approval, by non-binding advisory vote, of our executive compensation                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        2761861 |                0 | FOR         |                                  2761861 | FOR                         |  |
| AVALO THERAPEUTICS INC       | 05338F306 | 06/17/2025     | To approve, on a nonbinding advisory basis, a "Say-on-Pay" resolution regarding the compensation of our named executive officers                                                                      | SECTION 14A SAY-ON-PAY VOTES |         483000 |                0 | FOR         |                                   483000 | FOR                         |  |
| CABALETTA BIO INC            | 12674W109 | 06/09/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |          86795 |                0 | FOR         |                                    86795 | FOR                         |  |
| CABALETTA BIO INC            | 12674W109 | 06/09/2025     | To approve, on a non-binding, advisory basis, the preferred frequency of future advisory votes on compensation of our named executive officers                                                        | SECTION 14A SAY-ON-PAY VOTES |          86795 |                0 | FOR         |                                    86795 | FOR                         |  |
| CIDARA THERAPEUTICS INC      | 171757206 | 06/18/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |        1005901 |                0 | FOR         |                                  1005901 | FOR                         |  |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | 06/20/2025     | To receive and approve, on an advisory basis, the Company's UK statutory directors' remuneration report for the financial year ended December 31, 2024                                                | SECTION 14A SAY-ON-PAY VOTES |        2890816 |                0 | FOR         |                                  2890816 | FOR                         |  |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | 06/20/2025     | To receive and approve the Directors' Remuneration Policy as set out on pages A-3 to A-25 of the Company's UK statutory directors' remuneration report for the financial year ended December 31, 2024 | SECTION 14A SAY-ON-PAY VOTES |        2890816 |                0 | FOR         |                                  2890816 | FOR                         |  |
| COGENT BIOSCIENCES INC       | 19240Q201 | 06/04/2025     | To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers                                                                                              | SECTION 14A SAY-ON-PAY VOTES |        6964375 |                0 | FOR         |                                  6964375 | FOR                         |  |
| DIANTHUS THERAPEUTICS INC    | 252828108 | 05/22/2025     | To approve, on an advisory basis, the compensation paid to our named executive officers                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |        1501624 |                0 | FOR         |                                  1501624 | FOR                         |  |
| DYNE THERAPEUTICS INC        | 26818M108 | 05/30/2025     | To vote, on an advisory basis, to approve the compensation of our named executive officers                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |        2650150 |                0 | FOR         |                                  2650150 | FOR                         |  |
| DYNE THERAPEUTICS INC        | 26818M108 | 05/30/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers                                                                                | SECTION 14A SAY-ON-PAY VOTES |        2650150 |                0 | FOR         |                                  2650150 | FOR                         |  |
| EYEPOINT PHARMACEUTICALS INC | 30233G209 | 06/18/2025     | To approve, on an advisory basis, the compensation paid to the Company's named executive officers                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |        3572335 |                0 | FOR         |                                  3572335 | FOR                         |  |
| EYEPOINT PHARMACEUTICALS INC | 30233G209 | 06/18/2025     | To vote, on an advisory basis, on the frequency of advisory stockholder votes on the compensation paid to our named executive officers                                                                | SECTION 14A SAY-ON-PAY VOTES |        3572335 |                0 | FOR         |                                  3572335 | FOR                         |  |
| FULCRUM THERAPEUTICS INC     | 359616109 | 06/26/2025     | A non-binding advisory vote to approve the compensation of our named executive officers                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |        5250000 |                0 | FOR         |                                  5250000 | FOR                         |  |
| FULCRUM THERAPEUTICS INC     | 359616109 | 06/26/2025     | A non-binding advisory vote on the frequency of future advisory votes on the compensation of our named executive officers                                                                             | SECTION 14A SAY-ON-PAY VOTES |        5250000 |                0 | FOR         |                                  5250000 | FOR                         |  |
| STRUCTURE THERAPEUTICS INC   | 86366E106 | 06/23/2025     | To approve, on an advisory basis, the compensation of the Company's Named Executive Officers                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |        1063000 |                0 | FOR         |                                  1063000 | FOR                         |  |
| STRUCTURE THERAPEUTICS INC   | 86366E106 | 06/23/2025     | To indicate, on an advisory basis, the preferred frequency of shareholder advisory votes on the compensation of the Company's Named Executive Officers                                                | SECTION 14A SAY-ON-PAY VOTES |        1063000 |                0 | FOR         |                                  1063000 | FOR                         |  |
| DISC MEDICINE INC            | 254604101 | 06/11/2025     | To approve, on a non-binding, advisory basis, the compensation paid to our named executive officers                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         465257 |                0 | FOR         |                                   465257 | FOR                         |  |
| DISC MEDICINE INC            | 254604101 | 06/11/2025     | To recommend, by a non-binding advisory vote, the frequency of future advisory votes on the compensation paid to our named executive officers                                                         | SECTION 14A SAY-ON-PAY VOTES |         465257 |                0 | FOR         |                                   465257 | FOR                         |  |
| KODIAK SCIENCES INC          | 50015M109 | 06/02/2025     | Approve, on an advisory basis, the compensation of Kodiak's named executive officers                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |        1145538 |                0 | FOR         |                                  1145538 | FOR                         |  |
| SAVARA INC                   | 805111101 | 06/05/2025     | To approve, on an advisory basis, the compensation of our named executives                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |       12362205 |                0 | FOR         |                                 12362205 | FOR                         |  |
| SAVARA INC                   | 805111101 | 06/05/2025     | To indicate, on an advisory basis, the preferred frequency of holding an advisory vote on the compensation of our named executives                                                                    | SECTION 14A SAY-ON-PAY VOTES |       12362205 |                0 | FOR         |                                 12362205 | FOR                         |  |
| SILENCE THERAPEUTICS PLC     | 82686Q101 | 06/26/2025     | To approve, on an advisory basis, the compensation of our named executive officers                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |        3033560 |                0 | FOR         |                                  3033560 | FOR                         |  |
| SILENCE THERAPEUTICS PLC     | 82686Q101 | 06/26/2025     | To indicate, on an advisory basis, the preferred frequency of shareholder advisory votes on the compensation of our named executive officers                                                          | SECTION 14A SAY-ON-PAY VOTES |        3033560 |                0 | FOR         |                                  3033560 | FOR                         |  |
| TANGO THERAPEUTICS INC       | 87583X109 | 06/05/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |       10736000 |                0 | FOR         |                                 10736000 | FOR                         |  |
| TANGO THERAPEUTICS INC       | 87583X109 | 06/05/2025     | To vote on a non-binding, advisory basis, on the frequency of future non-binding, advisory votes on executive compensation                                                                            | SECTION 14A SAY-ON-PAY VOTES |       10736000 |                0 | FOR         |                                 10736000 | FOR                         |  |
| VENTYX BIOSCIENCES INC       | 92332V107 | 06/04/2025     | To approve, on an advisory basis, the compensation of the named executive officers                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |         316195 |                0 | FOR         |                                   316195 | FOR                         |  |
| XENCOR INC                   | 98401F105 | 06/12/2025     | To approve, on an advisory (non-binding) basis, the compensation of the Company's named executive officers                                                                                            | SECTION 14A SAY-ON-PAY VOTES |        2452138 |                0 | FOR         |                                  2452138 | FOR                         |  |
| COMPASS PATHWAYS LTD         | 20451W101 | 06/12/2025     | to approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers for the year ended December 31, 2024                                                         | SECTION 14A SAY-ON-PAY VOTES |        3858000 |                0 | FOR         |                                  3858000 | FOR                         |  |
| NEKTAR THERAPEUTICS          | 640268306 | 05/23/2025     | To approve a non-binding advisory resolution regarding our executive compensation                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |        4000000 |                0 | FOR         |                                  4000000 | FOR                         |  |
| OCULAR THERAPEUTIX INC       | 67576A100 | 06/11/2025     | To hold an advisory vote on named executive officer compensation                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |        5319148 |                0 | FOR         |                                  5319148 | FOR                         |  |
| RAPT THERAPEUTICS INC        | 75382E208 | 05/29/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |       13090200 |                0 | FOR         |                                 13090200 | FOR                         |  |
| RAPT THERAPEUTICS INC        | 75382E208 | 05/29/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's named executive officers                                                | SECTION 14A SAY-ON-PAY VOTES |       13090200 |                0 | FOR         |                                 13090200 | FOR                         |  |
| KURA ONCOLOGY INC            | 50127T109 | 06/05/2025     | To approve, on an advisory basis, the compensation of our named executive officers                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |         735184 |                0 | FOR         |                                   735184 | FOR                         |  |

## N-PX: Signature Block

**Reporting Person:** TCG Crossover Management, LLC

**By (Signature):** Craig Skaling

**By (Printed Signature):** Craig Skaling

**By (Title):** Chief Financial Officer

**Date:** 08/29/2025