# EDGAR Filing Document

**Accession Number:** 0001906594
**File Stem:** 0001906594-23-000002
**Filing Date:** 2023-1
**Character Count:** 41929
**Document Hash:** ba256985db6536cfd9b298bce4b3bbb2
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001906594-23-000002.hdr.sgml**: 20230131

**ACCESSION NUMBER**: 0001906594-23-000002

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230131

**DATE AS OF CHANGE**: 20230131

**EFFECTIVENESS DATE**: 20230131

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** China Universal Asset Management Co., Ltd.
- **CENTRAL INDEX KEY:** 0001906594
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** F4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-21774
- **FILM NUMBER:** 23570667

**BUSINESS ADDRESS:**
- **STREET 1:** CUAM BUILDING,728 WAIMA ROAD
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200001
- **BUSINESS PHONE:** 862128932888

**MAIL ADDRESS:**
- **STREET 1:** CUAM BUILDING,728 WAIMA ROAD
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200001

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2022

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** China Universal Asset Management Co. Ltd.<br>**Address:** CUAM BUILDING728 WAIMA ROAD<br>SHANGHAI, F4 200001

**Form 13F File Number:** 028-21774

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Li Peng<br>**Title:** Chief Compliance Officer<br>**Phone:** 86-021-20373399

**Signature, Place, and Date of Signing:**

Li Peng  Shanghai, F4  01-31-2023<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 391

**Form 13F Information Table Value Total:** $248733

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| AMAZON.COM INC | Common Stock | 023135106 |  | 14336 | 170668 | SH |  | SOLE |  | 170668 | 0 | 0 |
| MICROSOFT CORP | Common Stock | 594918104 |  | 13202 | 55050 | SH |  | SOLE |  | 55050 | 0 | 0 |
| IQIYI INC-ADR | ADR | 46267X108 |  | 12818 | 2418500 | SH |  | SOLE |  | 2418500 | 0 | 0 |
| PINDUODUO ADR | ADR | 722304102 |  | 10703 | 131240 | SH |  | SOLE |  | 131240 | 0 | 0 |
| UNITEDHEALTH | Common Stock | 91324P102 |  | 7455 | 14061 | SH |  | SOLE |  | 14061 | 0 | 0 |
| MERCK  CO. INC. | Common Stock | 58933Y105 |  | 7221 | 64764 | SH |  | SOLE |  | 64764 | 0 | 0 |
| VISA INC-CLASS A SHARES | Common Stock | 92826C839 |  | 5911 | 28450 | SH |  | SOLE |  | 28450 | 0 | 0 |
| SERVICENOW INC | Common Stock | 81762P102 |  | 5766 | 14850 | SH |  | SOLE |  | 14850 | 0 | 0 |
| ANALOG DEVICES INC | Common Stock | 032654105 |  | 5495 | 33500 | SH |  | SOLE |  | 33500 | 0 | 0 |
| ELI LILLY  CO | Common Stock | 532457108 |  | 5328 | 14565 | SH |  | SOLE |  | 14565 | 0 | 0 |
| VERTEX PHARMACEUTICALS INC | Common Stock | 92532F100 |  | 4847 | 16786 | SH |  | SOLE |  | 16786 | 0 | 0 |
| APPLE INC | Common Stock | 037833100 |  | 4236 | 32600 | SH |  | SOLE |  | 32600 | 0 | 0 |
| WORKDAY INC-CLASS A | Common Stock | 98138H101 |  | 3832 | 22900 | SH |  | SOLE |  | 22900 | 0 | 0 |
| COSTCO WHOLESALE CORP | Common Stock | 22160K105 |  | 3756 | 8228 | SH |  | SOLE |  | 8228 | 0 | 0 |
| ON SEMICONDUCTOR | Common Stock | 682189105 |  | 3742 | 60000 | SH |  | SOLE |  | 60000 | 0 | 0 |
| ALPHABET INC-CL A | Common Stock | 02079K305 |  | 3423 | 38800 | SH |  | SOLE |  | 38800 | 0 | 0 |
| DEXCOM INC | Common Stock | 252131107 |  | 3415 | 30159 | SH |  | SOLE |  | 30159 | 0 | 0 |
| RAMBUS INC | Common Stock | 750917106 |  | 3331 | 93000 | SH |  | SOLE |  | 93000 | 0 | 0 |
| LULULEMON ATHLETICA INC | Common Stock | 550021109 |  | 3315 | 10348 | SH |  | SOLE |  | 10348 | 0 | 0 |
| HOME DEPOT INC | Common Stock | 437076102 |  | 3236 | 10244 | SH |  | SOLE |  | 10244 | 0 | 0 |
| ALNYLAM PHARMACEUTICALS INC | Common Stock | 02043Q107 |  | 3233 | 13604 | SH |  | SOLE |  | 13604 | 0 | 0 |
| FORTINET INC | Common Stock | 34959E109 |  | 3178 | 65000 | SH |  | SOLE |  | 65000 | 0 | 0 |
| WOLFSPEED INC | Common Stock | 977852102 |  | 3132 | 45369 | SH |  | SOLE |  | 45369 | 0 | 0 |
| UNIQURE NV | Common Stock | N90064101 |  | 3015 | 132980 | SH |  | SOLE |  | 132980 | 0 | 0 |
| KEYSIGHT TECHNOLOGIES IN | Common Stock | 49338L103 |  | 2994 | 17500 | SH |  | SOLE |  | 17500 | 0 | 0 |
| ADOBE SYSTEMS INC | Common Stock | 00724F101 |  | 2961 | 8800 | SH |  | SOLE |  | 8800 | 0 | 0 |
| BIONTECH SE-ADR | ADR | 09075V102 |  | 2864 | 19065 | SH |  | SOLE |  | 19065 | 0 | 0 |
| TAIWAN SEMICONDUCTOR-SP ADR | ADR | 874039100 |  | 2861 | 38200 | SH |  | SOLE |  | 38200 | 0 | 0 |
| SALESFORCE INC | Common Stock | 79466L302 |  | 2771 | 20900 | SH |  | SOLE |  | 20900 | 0 | 0 |
| MARVELL TECHNOLOGY GROUP LTD | Common Stock | 573874104 |  | 2722 | 73500 | SH |  | SOLE |  | 73500 | 0 | 0 |
| BROADCOM LTD | Common Stock | 11135F101 |  | 2712 | 4850 | SH |  | SOLE |  | 4850 | 0 | 0 |
| BIOMARIN PHARMACEUTICAL INC | Common Stock | 09061G101 |  | 2683 | 25930 | SH |  | SOLE |  | 25930 | 0 | 0 |
| INTUITIVE SURGICAL INC | Common Stock | 46120E602 |  | 2546 | 9595 | SH |  | SOLE |  | 9595 | 0 | 0 |
| ISHARES GOLD TRUST | ETP | 464285204 |  | 2525 | 73000 | SH |  | SOLE |  | 73000 | 0 | 0 |
| PALO ALTO NETWORKS INC | Common Stock | 697435105 |  | 2512 | 18000 | SH |  | SOLE |  | 18000 | 0 | 0 |
| CATALENT INC | Common Stock | 148806102 |  | 2508 | 55723 | SH |  | SOLE |  | 55723 | 0 | 0 |
| SPDR GOLD SHARES | ETP | 78463V107 |  | 2494 | 14700 | SH |  | SOLE |  | 14700 | 0 | 0 |
| ASML HOLDING NV-NY REG SHS | NY Reg Shrs | N07059210 |  | 2459 | 4500 | SH |  | SOLE |  | 4500 | 0 | 0 |
| abrdn Gold ETF Trust | ETP | 00326A104 |  | 2446 | 140000 | SH |  | SOLE |  | 140000 | 0 | 0 |
| MASTERCARD INC - A | Common Stock | 57636Q104 |  | 2434 | 7000 | SH |  | SOLE |  | 7000 | 0 | 0 |
| AUTODESK INC | Common Stock | 052769106 |  | 2233 | 11950 | SH |  | SOLE |  | 11950 | 0 | 0 |
| UBER TECHNOLOGIES INC | Common Stock | 90353T100 |  | 2226 | 90000 | SH |  | SOLE |  | 90000 | 0 | 0 |
| AIRBNB INC-CLASS A | Common Stock | 009066101 |  | 2166 | 25338 | SH |  | SOLE |  | 25338 | 0 | 0 |
| DOORDASH INC - A | Common Stock | 25809K105 |  | 2042 | 41824 | SH |  | SOLE |  | 41824 | 0 | 0 |
| TESLA INC | Common Stock | 88160R101 |  | 2012 | 16331 | SH |  | SOLE |  | 16331 | 0 | 0 |
| Meta Platforms Inc. | Common Stock | 30303M102 |  | 2003 | 16644 | SH |  | SOLE |  | 16644 | 0 | 0 |
| TOWER SEMICONDUCTOR LTD | Common Stock | M87915274 |  | 1944 | 45000 | SH |  | SOLE |  | 45000 | 0 | 0 |
| SYNOPSYS INC | Common Stock | 871607107 |  | 1916 | 6000 | SH |  | SOLE |  | 6000 | 0 | 0 |
| NVIDIA CORP | Common Stock | 67066G104 |  | 1914 | 13100 | SH |  | SOLE |  | 13100 | 0 | 0 |
| CROWDSTRIKE HOLDINGS INC - A | Common Stock | 22788C105 |  | 1758 | 16700 | SH |  | SOLE |  | 16700 | 0 | 0 |
| ADVANCED MICRO DEVICES | Common Stock | 007903107 |  | 1736 | 26800 | SH |  | SOLE |  | 26800 | 0 | 0 |
| ATLASSIAN CORP PLC-CLASS A | Common Stock | 049468101 |  | 1711 | 13300 | SH |  | SOLE |  | 13300 | 0 | 0 |
| MODERNA INC | Common Stock | 60770K107 |  | 1704 | 9489 | SH |  | SOLE |  | 9489 | 0 | 0 |
| BATH  BODY WORKS INC | Common Stock | 070830104 |  | 1568 | 37206 | SH |  | SOLE |  | 37206 | 0 | 0 |
| NOVO-NORDISK A/S-SPONS ADR | ADR | 670100205 |  | 1548 | 11440 | SH |  | SOLE |  | 11440 | 0 | 0 |
| KE HOLDINGS INC | ADR | 482497104 |  | 1470 | 105300 | SH |  | SOLE |  | 105300 | 0 | 0 |
| ALBEMARLE CORP | Common Stock | 012653101 |  | 1456 | 6700 | SH |  | SOLE |  | 6700 | 0 | 0 |
| SPDR S BIOTECH ETF | ETP | 78464A870 |  | 1406 | 16937 | SH |  | SOLE |  | 16937 | 0 | 0 |
| BIOGEN INC | Common Stock | 09062X103 |  | 1233 | 4452 | SH |  | SOLE |  | 4452 | 0 | 0 |
| Block Inc | Common Stock | 852234103 |  | 1232 | 19600 | SH |  | SOLE |  | 19600 | 0 | 0 |
| HALOZYME THERAPEUTICS INC | Common Stock | 40637H109 |  | 1231 | 21636 | SH |  | SOLE |  | 21636 | 0 | 0 |
| LI AUTO INC - ADR | ADR | 50202M102 |  | 1122 | 55000 | SH |  | SOLE |  | 55000 | 0 | 0 |
| DECKERS OUTDOOR CORP | Common Stock | 243537107 |  | 930 | 2329 | SH |  | SOLE |  | 2329 | 0 | 0 |
| TARGET CORP | Common Stock | 87612E106 |  | 925 | 6204 | SH |  | SOLE |  | 6204 | 0 | 0 |
| BOOKING HOLDINGS INC | Common Stock | 09857L108 |  | 913 | 453 | SH |  | SOLE |  | 453 | 0 | 0 |
| NIKE INC -CL B | Common Stock | 654106103 |  | 910 | 7779 | SH |  | SOLE |  | 7779 | 0 | 0 |
| DINGDONG CAYMAN LTD -SPN ADR | ADR | 25445D101 |  | 901 | 211114 | SH |  | SOLE |  | 211114 | 0 | 0 |
| IDEXX LABORATORIES INC | Common Stock | 45168D104 |  | 893 | 2190 | SH |  | SOLE |  | 2190 | 0 | 0 |
| GILEAD SCIENCES INC | Common Stock | 375558103 |  | 866 | 10089 | SH |  | SOLE |  | 10089 | 0 | 0 |
| H World Group Ltd | ADR | 44332N106 |  | 861 | 20300 | SH |  | SOLE |  | 20300 | 0 | 0 |
| On Holding AG | Common Stock | H5919C104 |  | 848 | 49444 | SH |  | SOLE |  | 49444 | 0 | 0 |
| AMGEN INC | Common Stock | 031162100 |  | 813 | 3094 | SH |  | SOLE |  | 3094 | 0 | 0 |
| WALT DISNEY CO/THE | Common Stock | 254687106 |  | 812 | 9347 | SH |  | SOLE |  | 9347 | 0 | 0 |
| ILLUMINA INC | Common Stock | 452327109 |  | 802 | 3964 | SH |  | SOLE |  | 3964 | 0 | 0 |
| ULTA BEAUTY INC | Common Stock | 90384S303 |  | 790 | 1684 | SH |  | SOLE |  | 1684 | 0 | 0 |
| REGENERON PHARMACEUTICALS | Common Stock | 75886F107 |  | 785 | 1088 | SH |  | SOLE |  | 1088 | 0 | 0 |
| DANAHER CORP | Common Stock | 235851102 |  | 782 | 2943 | SH |  | SOLE |  | 2943 | 0 | 0 |
| DOLLAR TREE INC | Common Stock | 256746108 |  | 733 | 5185 | SH |  | SOLE |  | 5185 | 0 | 0 |
| SHOPIFY INC - CLASS A | Common Stock | 82509L107 |  | 709 | 20425 | SH |  | SOLE |  | 20425 | 0 | 0 |
| NEW ORIENTAL EDUCATION-SP ADR | ADR | 647581206 |  | 685 | 19673 | SH |  | SOLE |  | 19673 | 0 | 0 |
| SKECHERS USA INC-CL A | Common Stock | 830566105 |  | 683 | 16273 | SH |  | SOLE |  | 16273 | 0 | 0 |
| GENERAL MOTORS CO | Common Stock | 37045V100 |  | 673 | 20000 | SH |  | SOLE |  | 20000 | 0 | 0 |
| CHARGEPOINT HOLDINGS INC | Common Stock | 15961R105 |  | 667 | 70000 | SH |  | SOLE |  | 70000 | 0 | 0 |
| DOCUSIGN INC | Common Stock | 256163106 |  | 554 | 10000 | SH |  | SOLE |  | 10000 | 0 | 0 |
| QUALCOMM INC | Common Stock | 747525103 |  | 550 | 5000 | SH |  | SOLE |  | 5000 | 0 | 0 |
| FULL TRUCK ALLIANCE | ADR | 35969L108 |  | 545 | 68100 | SH |  | SOLE |  | 68100 | 0 | 0 |
| REPLIGEN CORP | Common Stock | 759916109 |  | 500 | 2956 | SH |  | SOLE |  | 2956 | 0 | 0 |
| FERRARI NV | Common Stock | N3167Y103 |  | 428 | 2000 | SH |  | SOLE |  | 2000 | 0 | 0 |
| ASTRAZENECA PLC-SPONS ADR | ADR | 046353108 |  | 421 | 6207 | SH |  | SOLE |  | 6207 | 0 | 0 |
| Trip.com Grp Ltd | ADR | 89677Q107 |  | 409 | 11900 | SH |  | SOLE |  | 11900 | 0 | 0 |
| BILIBILI INC-SPONSORED ADR | ADR | 090040106 |  | 404 | 17074 | SH |  | SOLE |  | 17074 | 0 | 0 |
| HILTON WORLDWIDE HOLDINGS IN | Common Stock | 43300A203 |  | 377 | 2987 | SH |  | SOLE |  | 2987 | 0 | 0 |
| UNITY SOFTWARE INC | Common Stock | 91332U101 |  | 373 | 13048 | SH |  | SOLE |  | 13048 | 0 | 0 |
| CAPRI HOLDINGS LTD | Common Stock | G1890L107 |  | 343 | 5987 | SH |  | SOLE |  | 5987 | 0 | 0 |
| STAAR SURGICAL CO | Common Stock | 852312305 |  | 330 | 6803 | SH |  | SOLE |  | 6803 | 0 | 0 |
| ALPHABET INC-CL C | Common Stock | 02079K107 |  | 317 | 3574 | SH |  | SOLE |  | 3574 | 0 | 0 |
| EURONAV NV | Common Stock | B38564108 |  | 273 | 16000 | SH |  | SOLE |  | 16000 | 0 | 0 |
| HORIZON THERAPEUTICS PLC | Common Stock | G46188101 |  | 262 | 2302 | SH |  | SOLE |  | 2302 | 0 | 0 |
| DOMINO'S PIZZA INC | Common Stock | 25754A201 |  | 256 | 739 | SH |  | SOLE |  | 739 | 0 | 0 |
| ROBLOX CORP -CLASS A | Common Stock | 771049103 |  | 255 | 8960 | SH |  | SOLE |  | 8960 | 0 | 0 |
| CANADA GOOSE HOLDINGS INC | Common Stock | 135086106 |  | 251 | 14100 | SH |  | SOLE |  | 14100 | 0 | 0 |
| SEAGEN INC | Common Stock | 81181C104 |  | 242 | 1886 | SH |  | SOLE |  | 1886 | 0 | 0 |
| AUTOLIV INC | Common Stock | 052800109 |  | 230 | 3000 | SH |  | SOLE |  | 3000 | 0 | 0 |
| ROSS STORES INC | Common Stock | 778296103 |  | 206 | 1775 | SH |  | SOLE |  | 1775 | 0 | 0 |
| RALPH LAUREN CORP | Common Stock | 751212101 |  | 189 | 1776 | SH |  | SOLE |  | 1776 | 0 | 0 |
| INCYTE CORP | Common Stock | 45337C102 |  | 182 | 2260 | SH |  | SOLE |  | 2260 | 0 | 0 |
| ROYALTY PHARMA PLC- CL A | Common Stock | G7709Q104 |  | 177 | 4481 | SH |  | SOLE |  | 4481 | 0 | 0 |
| ZOOM VIDEO COMMUNICATIONS-A | Common Stock | 98980L101 |  | 165 | 2440 | SH |  | SOLE |  | 2440 | 0 | 0 |
| CRISPR THERAPEUTICS AG | Common Stock | H17182108 |  | 146 | 3598 | SH |  | SOLE |  | 3598 | 0 | 0 |
| ZOETIS INC | Common Stock | 98978V103 |  | 144 | 986 | SH |  | SOLE |  | 986 | 0 | 0 |
| SANOFI-ADR | ADR | 80105N105 |  | 142 | 2935 | SH |  | SOLE |  | 2935 | 0 | 0 |
| MELCO RESORTS  ENTERT-ADR | ADR | 585464100 |  | 141 | 12300 | SH |  | SOLE |  | 12300 | 0 | 0 |
| VIATRIS INC | Common Stock | 92556V106 |  | 137 | 12320 | SH |  | SOLE |  | 12320 | 0 | 0 |
| PACIFIC BIOSCIENCES OF CALIF | Common Stock | 69404D108 |  | 132 | 16100 | SH |  | SOLE |  | 16100 | 0 | 0 |
| UNITED THERAPEUTICS CORP | Common Stock | 91307C102 |  | 129 | 463 | SH |  | SOLE |  | 463 | 0 | 0 |
| ARGENX SE - ADR | ADR | 04016X101 |  | 120 | 316 | SH |  | SOLE |  | 316 | 0 | 0 |
| NEUROCRINE BIOSCIENCES INC | Common Stock | 64125C109 |  | 117 | 977 | SH |  | SOLE |  | 977 | 0 | 0 |
| SAREPTA THERAPEUTICS INC | Common Stock | 803607100 |  | 116 | 892 | SH |  | SOLE |  | 892 | 0 | 0 |
| CHIPOTLE MEXICAN GRILL INC | Common Stock | 169656105 |  | 112 | 81 | SH |  | SOLE |  | 81 | 0 | 0 |
| BEIGENE LTD-ADR | ADR | 07725L102 |  | 107 | 486 | SH |  | SOLE |  | 486 | 0 | 0 |
| CVS HEALTH CORP | Common Stock | 126650100 |  | 104 | 1115 | SH |  | SOLE |  | 1115 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | Common Stock | G50871105 |  | 102 | 639 | SH |  | SOLE |  | 639 | 0 | 0 |
| ALIGN TECHNOLOGY INC | Common Stock | 016255101 |  | 92 | 435 | SH |  | SOLE |  | 435 | 0 | 0 |
| AMBARELLA INC | Common Stock | G037AX101 |  | 82 | 1000 | SH |  | SOLE |  | 1000 | 0 | 0 |
| ALIBABA GROUP HOLDING LTD | ADR | 01609W102 |  | 81 | 920 | SH |  | SOLE |  | 920 | 0 | 0 |
| NOVOCURE LTD | Common Stock | G6674U108 |  | 78 | 1066 | SH |  | SOLE |  | 1066 | 0 | 0 |
| CARNIVAL CORP | Common Stock | 143658300 |  | 77 | 9580 | SH |  | SOLE |  | 9580 | 0 | 0 |
| AMPHENOL CORP-CL A | Common Stock | 032095101 |  | 76 | 1000 | SH |  | SOLE |  | 1000 | 0 | 0 |
| ASCENDIS PHARMA A/S - ADR | ADR | 04351P101 |  | 69 | 567 | SH |  | SOLE |  | 567 | 0 | 0 |
| KARUNA THERAPEUTICS INC | Common Stock | 48576A100 |  | 69 | 349 | SH |  | SOLE |  | 349 | 0 | 0 |
| MEDPACE HOLDINGS INC | Common Stock | 58506Q109 |  | 67 | 316 | SH |  | SOLE |  | 316 | 0 | 0 |
| GUARDANT HEALTH INC | Common Stock | 40131M109 |  | 66 | 2436 | SH |  | SOLE |  | 2436 | 0 | 0 |
| ROIVANT SCIENCES LTD | Common Stock | G76279101 |  | 59 | 7369 | SH |  | SOLE |  | 7369 | 0 | 0 |
| APELLIS PHARMACEUTICALS INC | Common Stock | 03753U106 |  | 58 | 1123 | SH |  | SOLE |  | 1123 | 0 | 0 |
| IONIS PHARMACEUTICALS INC | Common Stock | 462222100 |  | 55 | 1443 | SH |  | SOLE |  | 1443 | 0 | 0 |
| EXELIXIS INC | Common Stock | 30161Q104 |  | 53 | 3277 | SH |  | SOLE |  | 3277 | 0 | 0 |
| INTRA-CELLULAR THERAPIES INC | Common Stock | 46116X101 |  | 51 | 962 | SH |  | SOLE |  | 962 | 0 | 0 |
| MADRIGAL PHARMACEUTICALS INC | Common Stock | 558868105 |  | 51 | 174 | SH |  | SOLE |  | 174 | 0 | 0 |
| PROMETHEUS BIOSCIENCES INC | Common Stock | 74349U108 |  | 47 | 426 | SH |  | SOLE |  | 426 | 0 | 0 |
| ALKERMES PLC | Common Stock | G01767105 |  | 44 | 1669 | SH |  | SOLE |  | 1669 | 0 | 0 |
| ARROWHEAD PHARMACEUTICALS IN | Common Stock | 04280A100 |  | 44 | 1077 | SH |  | SOLE |  | 1077 | 0 | 0 |
| CYTOKINETICS INC | Common Stock | 23282W605 |  | 44 | 961 | SH |  | SOLE |  | 961 | 0 | 0 |
| ZTO EXPRESS CAYMAN INC-ADR | ADR | 98980A105 |  | 43 | 1600 | SH |  | SOLE |  | 1600 | 0 | 0 |
| VAXCYTE INC | Common Stock | 92243G108 |  | 39 | 803 | SH |  | SOLE |  | 803 | 0 | 0 |
| DENALI THERAPEUTICS INC | Common Stock | 24823R105 |  | 38 | 1380 | SH |  | SOLE |  | 1380 | 0 | 0 |
| SYNEOS HEALTH INC | Common Stock | 87166B102 |  | 38 | 1045 | SH |  | SOLE |  | 1045 | 0 | 0 |
| BEAM THERAPEUTICS INC | Common Stock | 07373V105 |  | 37 | 952 | SH |  | SOLE |  | 952 | 0 | 0 |
| AMICUS THERAPEUTICS INC | Common Stock | 03152W109 |  | 35 | 2854 | SH |  | SOLE |  | 2854 | 0 | 0 |
| AXSOME THERAPEUTICS INC | Common Stock | 05464T104 |  | 34 | 441 | SH |  | SOLE |  | 441 | 0 | 0 |
| VIR BIOTECHNOLOGY INC | Common Stock | 92764N102 |  | 34 | 1353 | SH |  | SOLE |  | 1353 | 0 | 0 |
| INTELLIA THERAPEUTICS INC | Common Stock | 45826J105 |  | 33 | 954 | SH |  | SOLE |  | 954 | 0 | 0 |
| HARMONY BIOSCIENCES HOLDINGS | Common Stock | 413197104 |  | 33 | 603 | SH |  | SOLE |  | 603 | 0 | 0 |
| LEGEND BIOTECH CORP-ADR | ADR | 52490G102 |  | 33 | 658 | SH |  | SOLE |  | 658 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | Common Stock | 90400D108 |  | 33 | 712 | SH |  | SOLE |  | 712 | 0 | 0 |
| PROTHENA CORP PLC | Common Stock | G72800108 |  | 30 | 491 | SH |  | SOLE |  | 491 | 0 | 0 |
| ABCELLERA BIOLOGICS INC | Common Stock | 00288U106 |  | 29 | 2906 | SH |  | SOLE |  | 2906 | 0 | 0 |
| PTC THERAPEUTICS INC | Common Stock | 69366J200 |  | 28 | 731 | SH |  | SOLE |  | 731 | 0 | 0 |
| BLUEPRINT MEDICINES CORP | Common Stock | 09627Y109 |  | 27 | 608 | SH |  | SOLE |  | 608 | 0 | 0 |
| INSMED INC | Common Stock | 457669307 |  | 27 | 1376 | SH |  | SOLE |  | 1376 | 0 | 0 |
| MIRATI THERAPEUTICS INC | Common Stock | 60468T105 |  | 27 | 585 | SH |  | SOLE |  | 585 | 0 | 0 |
| ACADIA PHARMACEUTICALS INC | Common Stock | 004225108 |  | 26 | 1645 | SH |  | SOLE |  | 1645 | 0 | 0 |
| AKERO THERAPEUTICS INC | Common Stock | 00973Y108 |  | 26 | 475 | SH |  | SOLE |  | 475 | 0 | 0 |
| IVERIC BIO INC | Common Stock | 46583P102 |  | 26 | 1227 | SH |  | SOLE |  | 1227 | 0 | 0 |
| AMYLYX PHARMACEUTICALS INC | Common Stock | 03237H101 |  | 25 | 673 | SH |  | SOLE |  | 673 | 0 | 0 |
| XENON PHARMACEUTICALS INC | Common Stock | 98420N105 |  | 25 | 635 | SH |  | SOLE |  | 635 | 0 | 0 |
| IMMUNOVANT INC | Common Stock | 45258J102 |  | 23 | 1312 | SH |  | SOLE |  | 1312 | 0 | 0 |
| SAGE THERAPEUTICS INC | Common Stock | 78667J108 |  | 23 | 605 | SH |  | SOLE |  | 605 | 0 | 0 |
| BIOCRYST PHARMACEUTICALS INC | Common Stock | 09058V103 |  | 22 | 1893 | SH |  | SOLE |  | 1893 | 0 | 0 |
| ZAI LAB LTD-ADR | ADR | 98887Q104 |  | 22 | 701 | SH |  | SOLE |  | 701 | 0 | 0 |
| IMMUNITYBIO INC | Common Stock | 45256X103 |  | 21 | 4067 | SH |  | SOLE |  | 4067 | 0 | 0 |
| KRYSTAL BIOTECH INC | Common Stock | 501147102 |  | 21 | 262 | SH |  | SOLE |  | 262 | 0 | 0 |
| REVOLUTION MEDICINES INC | Common Stock | 76155X100 |  | 21 | 902 | SH |  | SOLE |  | 902 | 0 | 0 |
| SUPERNUS PHARMACEUTICALS INC | Common Stock | 868459108 |  | 20 | 549 | SH |  | SOLE |  | 549 | 0 | 0 |
| CHARLES RIVER LABORATORIES | Common Stock | 159864107 |  | 19 | 89 | SH |  | SOLE |  | 89 | 0 | 0 |
| EDWARDS LIFESCIENCES CORP | Common Stock | 28176E108 |  | 19 | 256 | SH |  | SOLE |  | 256 | 0 | 0 |
| ARVINAS INC | Common Stock | 04335A105 |  | 19 | 541 | SH |  | SOLE |  | 541 | 0 | 0 |
| IRONWOOD PHARMACEUTICALS INC | Common Stock | 46333X108 |  | 19 | 1558 | SH |  | SOLE |  | 1558 | 0 | 0 |
| MARAVAI LIFESCIENCES HLDGS-A | Common Stock | 56600D107 |  | 19 | 1336 | SH |  | SOLE |  | 1336 | 0 | 0 |
| VENTYX BIOSCIENCES INC | Common Stock | 92332V107 |  | 19 | 575 | SH |  | SOLE |  | 575 | 0 | 0 |
| GENMAB A/S -SP ADR | ADR | 372303206 |  | 18 | 434 | SH |  | SOLE |  | 434 | 0 | 0 |
| PACIRA BIOSCIENCES INC | Common Stock | 695127100 |  | 18 | 466 | SH |  | SOLE |  | 466 | 0 | 0 |
| RELAY THERAPEUTICS INC | Common Stock | 75943R102 |  | 18 | 1228 | SH |  | SOLE |  | 1228 | 0 | 0 |
| IQVIA HOLDINGS INC | Common Stock | 46266C105 |  | 17 | 84 | SH |  | SOLE |  | 84 | 0 | 0 |
| CHINOOK THERAPEUTICS INC | Common Stock | 16961L106 |  | 17 | 649 | SH |  | SOLE |  | 649 | 0 | 0 |
| RHYTHM PHARMACEUTICALS INC | Common Stock | 76243J105 |  | 17 | 572 | SH |  | SOLE |  | 572 | 0 | 0 |
| VERACYTE INC | Common Stock | 92337F107 |  | 17 | 729 | SH |  | SOLE |  | 729 | 0 | 0 |
| AGIOS PHARMACEUTICALS INC | Common Stock | 00847X104 |  | 16 | 558 | SH |  | SOLE |  | 558 | 0 | 0 |
| DAY ONE BIOPHARMACEUTICALS I | Common Stock | 23954D109 |  | 16 | 747 | SH |  | SOLE |  | 747 | 0 | 0 |
| SYNDAX PHARMACEUTICALS INC | Common Stock | 87164F105 |  | 16 | 612 | SH |  | SOLE |  | 612 | 0 | 0 |
| SPRINGWORKS THERAPEUTICS INC | Common Stock | 85205L107 |  | 16 | 634 | SH |  | SOLE |  | 634 | 0 | 0 |
| VERONA PHARMA PLC - ADR | ADR | 925050106 |  | 16 | 617 | SH |  | SOLE |  | 617 | 0 | 0 |
| XENCOR INC | Common Stock | 98401F105 |  | 16 | 609 | SH |  | SOLE |  | 609 | 0 | 0 |
| DICE THERAPEUTICS INC | Common Stock | 23345J104 |  | 15 | 484 | SH |  | SOLE |  | 484 | 0 | 0 |
| FIBROGEN INC | Common Stock | 31572Q808 |  | 15 | 955 | SH |  | SOLE |  | 955 | 0 | 0 |
| IMMUNOCORE HOLDINGS PLC-ADR | ADR | 45258D105 |  | 15 | 262 | SH |  | SOLE |  | 262 | 0 | 0 |
| NUVALENT INC-A | Common Stock | 670703107 |  | 15 | 518 | SH |  | SOLE |  | 518 | 0 | 0 |
| ROCKET PHARMACEUTICALS INC | Common Stock | 77313F106 |  | 15 | 769 | SH |  | SOLE |  | 769 | 0 | 0 |
| REVANCE THERAPEUTICS INC | Common Stock | 761330109 |  | 15 | 836 | SH |  | SOLE |  | 836 | 0 | 0 |
| ARCELLX INC | Common Stock | 03940C100 |  | 14 | 445 | SH |  | SOLE |  | 445 | 0 | 0 |
| AMPHASTAR PHARMACEUTICALS IN | Common Stock | 03209R103 |  | 14 | 491 | SH |  | SOLE |  | 491 | 0 | 0 |
| KYMERA THERAPEUTICS INC | Common Stock | 501575104 |  | 14 | 557 | SH |  | SOLE |  | 557 | 0 | 0 |
| MANNKIND CORP | Common Stock | 56400P706 |  | 14 | 2674 | SH |  | SOLE |  | 2674 | 0 | 0 |
| REPLIMUNE GROUP INC | Common Stock | 76029N106 |  | 14 | 505 | SH |  | SOLE |  | 505 | 0 | 0 |
| RECURSION PHARMACEUTICALS-A | Common Stock | 75629V104 |  | 14 | 1846 | SH |  | SOLE |  | 1846 | 0 | 0 |
| TRAVERE THERAPEUTICS INC | Common Stock | 89422G107 |  | 14 | 652 | SH |  | SOLE |  | 652 | 0 | 0 |
| TWIST BIOSCIENCE CORP | Common Stock | 90184D100 |  | 14 | 574 | SH |  | SOLE |  | 574 | 0 | 0 |
| KEROS THERAPEUTICS INC | Common Stock | 492327101 |  | 13 | 280 | SH |  | SOLE |  | 280 | 0 | 0 |
| BRIDGEBIO PHARMA INC | Common Stock | 10806X102 |  | 12 | 1519 | SH |  | SOLE |  | 1519 | 0 | 0 |
| CUREVAC NV | Common Stock | N2451R105 |  | 12 | 1933 | SH |  | SOLE |  | 1933 | 0 | 0 |
| EQRX INC | Common Stock | 26886C107 |  | 12 | 4962 | SH |  | SOLE |  | 4962 | 0 | 0 |
| MYRIAD GENETICS INC | Common Stock | 62855J104 |  | 12 | 823 | SH |  | SOLE |  | 823 | 0 | 0 |
| REATA PHARMACEUTICALS INC-A | Common Stock | 75615P103 |  | 12 | 323 | SH |  | SOLE |  | 323 | 0 | 0 |
| AVIDITY BIOSCIENCES INC | Common Stock | 05370A108 |  | 12 | 553 | SH |  | SOLE |  | 553 | 0 | 0 |
| VERVE THERAPEUTICS INC | Common Stock | 92539P101 |  | 12 | 626 | SH |  | SOLE |  | 626 | 0 | 0 |
| ZENTALIS PHARMACEUTICALS INC | Common Stock | 98943L107 |  | 12 | 579 | SH |  | SOLE |  | 579 | 0 | 0 |
| JD.COM INC-ADR | ADR | 47215P106 |  | 11 | 200 | SH |  | SOLE |  | 200 | 0 | 0 |
| ACLARIS THERAPEUTICS INC | Common Stock | 00461U105 |  | 11 | 678 | SH |  | SOLE |  | 678 | 0 | 0 |
| ADAPTIVE BIOTECHNOLOGIES | Common Stock | 00650F109 |  | 11 | 1453 | SH |  | SOLE |  | 1453 | 0 | 0 |
| DECIPHERA PHARMACEUTICALS IN | Common Stock | 24344T101 |  | 11 | 687 | SH |  | SOLE |  | 687 | 0 | 0 |
| IMMUNOGEN INC | Common Stock | 45253H101 |  | 11 | 2242 | SH |  | SOLE |  | 2242 | 0 | 0 |
| INHIBRX INC | Common Stock | 45720L107 |  | 11 | 442 | SH |  | SOLE |  | 442 | 0 | 0 |
| LIGAND PHARMACEUTICALS | Common Stock | 53220K504 |  | 11 | 171 | SH |  | SOLE |  | 171 | 0 | 0 |
| BELLUS HEALTH INC | Common Stock | 07987C204 |  | 10 | 1277 | SH |  | SOLE |  | 1277 | 0 | 0 |
| CRINETICS PHARMACEUTICALS IN | Common Stock | 22663K107 |  | 10 | 547 | SH |  | SOLE |  | 547 | 0 | 0 |
| ENANTA PHARMACEUTICALS INC | Common Stock | 29251M106 |  | 10 | 211 | SH |  | SOLE |  | 211 | 0 | 0 |
| FATE THERAPEUTICS INC | Common Stock | 31189P102 |  | 10 | 987 | SH |  | SOLE |  | 987 | 0 | 0 |
| GRIFOLS SA-ADR | ADR | 398438408 |  | 10 | 1129 | SH |  | SOLE |  | 1129 | 0 | 0 |
| IOVANCE BIOTHERAPEUTICS INC | Common Stock | 462260100 |  | 10 | 1603 | SH |  | SOLE |  | 1603 | 0 | 0 |
| MORPHIC HOLDING INC | Common Stock | 61775R105 |  | 10 | 392 | SH |  | SOLE |  | 392 | 0 | 0 |
| PLIANT THERAPEUTICS INC | Common Stock | 729139105 |  | 10 | 495 | SH |  | SOLE |  | 495 | 0 | 0 |
| REGENXBIO INC | Common Stock | 75901B107 |  | 10 | 439 | SH |  | SOLE |  | 439 | 0 | 0 |
| NOVAVAX INC | Common Stock | 670002401 |  | 9 | 854 | SH |  | SOLE |  | 854 | 0 | 0 |
| VEEVA SYSTEMS INC-CLASS A | Common Stock | 922475108 |  | 9 | 55 | SH |  | SOLE |  | 55 | 0 | 0 |
| ALLOGENE THERAPEUTICS INC | Common Stock | 019770106 |  | 9 | 1465 | SH |  | SOLE |  | 1465 | 0 | 0 |
| ANAPTYSBIO INC | Common Stock | 032724106 |  | 9 | 289 | SH |  | SOLE |  | 289 | 0 | 0 |
| ARCUTIS BIOTHERAPEUTICS INC | Common Stock | 03969K108 |  | 9 | 619 | SH |  | SOLE |  | 619 | 0 | 0 |
| GERON CORP | Common Stock | 374163103 |  | 9 | 3873 | SH |  | SOLE |  | 3873 | 0 | 0 |
| IDEAYA BIOSCIENCES INC | Common Stock | 45166A102 |  | 9 | 489 | SH |  | SOLE |  | 489 | 0 | 0 |
| INNOVIVA INC | Common Stock | 45781M101 |  | 9 | 709 | SH |  | SOLE |  | 709 | 0 | 0 |
| KURA ONCOLOGY INC | Common Stock | 50127T109 |  | 9 | 693 | SH |  | SOLE |  | 693 | 0 | 0 |
| LYELL IMMUNOPHARMA INC | Common Stock | 55083R104 |  | 9 | 2533 | SH |  | SOLE |  | 2533 | 0 | 0 |
| PROVENTION BIO INC | Common Stock | 74374N102 |  | 9 | 886 | SH |  | SOLE |  | 886 | 0 | 0 |
| SUMMIT THERAPEUTICS INC | Common Stock | 86627T108 |  | 9 | 2045 | SH |  | SOLE |  | 2045 | 0 | 0 |
| 10X GENOMICS INC-CLASS A | Common Stock | 88025U109 |  | 8 | 228 | SH |  | SOLE |  | 228 | 0 | 0 |
| ADMA BIOLOGICS INC | Common Stock | 000899104 |  | 8 | 1999 | SH |  | SOLE |  | 1999 | 0 | 0 |
| ALECTOR INC | Common Stock | 014442107 |  | 8 | 840 | SH |  | SOLE |  | 840 | 0 | 0 |
| ALTIMMUNE INC | Common Stock | 02155H200 |  | 8 | 499 | SH |  | SOLE |  | 499 | 0 | 0 |
| BICYCLE THERAPEUTICS PLC-ADR | ADR | 088786108 |  | 8 | 259 | SH |  | SOLE |  | 259 | 0 | 0 |
| COGENT BIOSCIENCES INC | Common Stock | 19240Q201 |  | 8 | 710 | SH |  | SOLE |  | 710 | 0 | 0 |
| COLLEGIUM PHARMACEUTICAL INC | Common Stock | 19459J104 |  | 8 | 341 | SH |  | SOLE |  | 341 | 0 | 0 |
| SANA BIOTECHNOLOGY INC | Common Stock | 799566104 |  | 8 | 1938 | SH |  | SOLE |  | 1938 | 0 | 0 |
| ARS PHARMACEUTICALS INC | Common Stock | 82835W108 |  | 8 | 953 | SH |  | SOLE |  | 953 | 0 | 0 |
| THERAVANCE BIOPHARMA INC | Common Stock | G8807B106 |  | 8 | 684 | SH |  | SOLE |  | 684 | 0 | 0 |
| SCHRODINGER INC | Common Stock | 80810D103 |  | 7 | 350 | SH |  | SOLE |  | 350 | 0 | 0 |
| DADA NEXUS LTD-ADR | ADR | 23344D108 |  | 7 | 1000 | SH |  | SOLE |  | 1000 | 0 | 0 |
| ALLAKOS INC | Common Stock | 01671P100 |  | 7 | 865 | SH |  | SOLE |  | 865 | 0 | 0 |
| ANI PHARMACEUTICALS INC | Common Stock | 00182C103 |  | 7 | 178 | SH |  | SOLE |  | 178 | 0 | 0 |
| ANAVEX LIFE SCIENCES CORP | Common Stock | 032797300 |  | 7 | 792 | SH |  | SOLE |  | 792 | 0 | 0 |
| 4D MOLECULAR THERAPEUTICS IN | Common Stock | 35104E100 |  | 7 | 329 | SH |  | SOLE |  | 329 | 0 | 0 |
| ITEOS THERAPEUTICS INC | Common Stock | 46565G104 |  | 7 | 361 | SH |  | SOLE |  | 361 | 0 | 0 |
| SERES THERAPEUTICS INC | Common Stock | 81750R102 |  | 7 | 1265 | SH |  | SOLE |  | 1265 | 0 | 0 |
| MIRUM PHARMACEUTICALS INC | Common Stock | 604749101 |  | 7 | 374 | SH |  | SOLE |  | 374 | 0 | 0 |
| MERUS NV | Common Stock | N5749R100 |  | 7 | 471 | SH |  | SOLE |  | 471 | 0 | 0 |
| RAPT THERAPEUTICS INC | Common Stock | 75382E109 |  | 7 | 345 | SH |  | SOLE |  | 345 | 0 | 0 |
| EXACT SCIENCES CORP | Common Stock | 30063P105 |  | 6 | 128 | SH |  | SOLE |  | 128 | 0 | 0 |
| PROCTER  GAMBLE CO/THE | Common Stock | 742718109 |  | 6 | 40 | SH |  | SOLE |  | 40 | 0 | 0 |
| AURINIA PHARMACEUTICALS INC | Common Stock | 05156V102 |  | 6 | 1444 | SH |  | SOLE |  | 1444 | 0 | 0 |
| BLUEBIRD BIO INC | Common Stock | 09609G100 |  | 6 | 842 | SH |  | SOLE |  | 842 | 0 | 0 |
| CARA THERAPEUTICS INC | Common Stock | 140755109 |  | 6 | 546 | SH |  | SOLE |  | 546 | 0 | 0 |
| COHERUS BIOSCIENCES INC | Common Stock | 19249H103 |  | 6 | 790 | SH |  | SOLE |  | 790 | 0 | 0 |
| CASTLE BIOSCIENCES INC | Common Stock | 14843C105 |  | 6 | 268 | SH |  | SOLE |  | 268 | 0 | 0 |
| DESIGN THERAPEUTICS INC | Common Stock | 25056L103 |  | 6 | 568 | SH |  | SOLE |  | 568 | 0 | 0 |
| DYNE THERAPEUTICS INC | Common Stock | 26818M108 |  | 6 | 530 | SH |  | SOLE |  | 530 | 0 | 0 |
| EDITAS MEDICINE INC | Common Stock | 28106W103 |  | 6 | 698 | SH |  | SOLE |  | 698 | 0 | 0 |
| 89BIO INC | Common Stock | 282559103 |  | 6 | 473 | SH |  | SOLE |  | 473 | 0 | 0 |
| EDGEWISE THERAPEUTICS INC | Common Stock | 28036F105 |  | 6 | 642 | SH |  | SOLE |  | 642 | 0 | 0 |
| GALAPAGOS NV-SPON ADR | ADR | 36315X101 |  | 6 | 136 | SH |  | SOLE |  | 136 | 0 | 0 |
| HUTCHMED CHINA-ADR | ADR | 44842L103 |  | 6 | 375 | SH |  | SOLE |  | 375 | 0 | 0 |
| HILLEVAX INC | Common Stock | 43157M102 |  | 6 | 339 | SH |  | SOLE |  | 339 | 0 | 0 |
| 23ANDME HOLDING CO -CLASS A | Common Stock | 90138Q108 |  | 6 | 2913 | SH |  | SOLE |  | 2913 | 0 | 0 |
| MERSANA THERAPEUTICS INC | Common Stock | 59045L106 |  | 6 | 1014 | SH |  | SOLE |  | 1014 | 0 | 0 |
| MAXCYTE INC | Common Stock | 57777K106 |  | 6 | 1037 | SH |  | SOLE |  | 1037 | 0 | 0 |
| REPARE THERAPEUTICS INC | Common Stock | 760273102 |  | 6 | 426 | SH |  | SOLE |  | 426 | 0 | 0 |
| TANGO THERAPEUTICS INC | Common Stock | 87583X109 |  | 6 | 896 | SH |  | SOLE |  | 896 | 0 | 0 |
| WAVE LIFE SCIENCES LTD | Common Stock | Y95308105 |  | 6 | 883 | SH |  | SOLE |  | 883 | 0 | 0 |
| NIU TECHNOLOGIES-SPONS ADR | ADR | 65481N100 |  | 5 | 1000 | SH |  | SOLE |  | 1000 | 0 | 0 |
| ABCAM PLC-SPON ADR | ADR | 000380204 |  | 5 | 315 | SH |  | SOLE |  | 315 | 0 | 0 |
| ALLOVIR INC | Common Stock | 019818103 |  | 5 | 947 | SH |  | SOLE |  | 947 | 0 | 0 |
| ALX ONCOLOGY HOLDINGS INC | Common Stock | 00166B105 |  | 5 | 414 | SH |  | SOLE |  | 414 | 0 | 0 |
| AMARIN CORP PLC -ADR | ADR | 023111206 |  | 5 | 4078 | SH |  | SOLE |  | 4078 | 0 | 0 |
| ARCTURUS THERAPEUTICS HOLDIN | Common Stock | 03969T109 |  | 5 | 269 | SH |  | SOLE |  | 269 | 0 | 0 |
| ARDELYX INC | Common Stock | 039697107 |  | 5 | 1904 | SH |  | SOLE |  | 1904 | 0 | 0 |
| CYMABAY THERAPEUTICS INC | Common Stock | 23257D103 |  | 5 | 860 | SH |  | SOLE |  | 860 | 0 | 0 |
| CULLINAN ONCOLOGY INC | Common Stock | 230031106 |  | 5 | 465 | SH |  | SOLE |  | 465 | 0 | 0 |
| CINCOR PHARMA INC | Common Stock | 17240Y109 |  | 5 | 444 | SH |  | SOLE |  | 444 | 0 | 0 |
| ERASCA INC | Common Stock | 29479A108 |  | 5 | 1243 | SH |  | SOLE |  | 1243 | 0 | 0 |
| ESPERION THERAPEUTICS INC | Common Stock | 29664W105 |  | 5 | 749 | SH |  | SOLE |  | 749 | 0 | 0 |
| INTERCEPT PHARMACEUTICALS IN | Common Stock | 45845P108 |  | 5 | 421 | SH |  | SOLE |  | 421 | 0 | 0 |
| IGM BIOSCIENCES INC | Common Stock | 449585108 |  | 5 | 296 | SH |  | SOLE |  | 296 | 0 | 0 |
| KINIKSA PHARMACEUTICALS-A | Common Stock | G5269C101 |  | 5 | 351 | SH |  | SOLE |  | 351 | 0 | 0 |
| KEZAR LIFE SCIENCES INC | Common Stock | 49372L100 |  | 5 | 695 | SH |  | SOLE |  | 695 | 0 | 0 |
| NURIX THERAPEUTICS INC | Common Stock | 67080M103 |  | 5 | 479 | SH |  | SOLE |  | 479 | 0 | 0 |
| PHATHOM PHARMACEUTICALS INC | Common Stock | 71722W107 |  | 5 | 423 | SH |  | SOLE |  | 423 | 0 | 0 |
| POSEIDA THERAPEUTICS INC | Common Stock | 73730P108 |  | 5 | 874 | SH |  | SOLE |  | 874 | 0 | 0 |
| PROTAGONIST THERAPEUTICS INC | Common Stock | 74366E102 |  | 5 | 500 | SH |  | SOLE |  | 500 | 0 | 0 |
| SANGAMO THERAPEUTICS INC | Common Stock | 800677106 |  | 5 | 1665 | SH |  | SOLE |  | 1665 | 0 | 0 |
| SIGA TECHNOLOGIES INC | Common Stock | 826917106 |  | 5 | 742 | SH |  | SOLE |  | 742 | 0 | 0 |
| SCHOLAR ROCK HOLDING CORP | Common Stock | 80706P103 |  | 5 | 525 | SH |  | SOLE |  | 525 | 0 | 0 |
| SUTRO BIOPHARMA INC | Common Stock | 869367102 |  | 5 | 583 | SH |  | SOLE |  | 583 | 0 | 0 |
| XPENG INC - ADR | ADR | 98422D105 |  | 4 | 400 | SH |  | SOLE |  | 400 | 0 | 0 |
| ARBUTUS BIOPHARMA CORP | Common Stock | 03879J100 |  | 4 | 1590 | SH |  | SOLE |  | 1590 | 0 | 0 |
| ADICET BIO INC | Common Stock | 007002108 |  | 4 | 435 | SH |  | SOLE |  | 435 | 0 | 0 |
| ATAI LIFE SCIENCES NV | Common Stock | N0731H103 |  | 4 | 1685 | SH |  | SOLE |  | 1685 | 0 | 0 |
| AVADEL PHARMACEUTICALS-ADR | ADR | 05337M104 |  | 4 | 618 | SH |  | SOLE |  | 618 | 0 | 0 |
| ATEA PHARMACEUTICALS INC | Common Stock | 04683R106 |  | 4 | 846 | SH |  | SOLE |  | 846 | 0 | 0 |
| BIOATLA INC | Common Stock | 09077B104 |  | 4 | 469 | SH |  | SOLE |  | 469 | 0 | 0 |
| CARIBOU BIOSCIENCES INC | Common Stock | 142038108 |  | 4 | 620 | SH |  | SOLE |  | 620 | 0 | 0 |
| EAGLE PHARMACEUTICALS INC | Common Stock | 269796108 |  | 4 | 132 | SH |  | SOLE |  | 132 | 0 | 0 |
| EVOLUS INC | Common Stock | 30052C107 |  | 4 | 571 | SH |  | SOLE |  | 571 | 0 | 0 |
| FULCRUM THERAPEUTICS INC | Common Stock | 359616109 |  | 4 | 529 | SH |  | SOLE |  | 529 | 0 | 0 |
| MONTE ROSA THERAPEUTICS INC | Common Stock | 61225M102 |  | 4 | 492 | SH |  | SOLE |  | 492 | 0 | 0 |
| HARROW HEALTH INC | Common Stock | 415858109 |  | 4 | 278 | SH |  | SOLE |  | 278 | 0 | 0 |
| INOVIO PHARMACEUTICALS INC | Common Stock | 45773H201 |  | 4 | 2535 | SH |  | SOLE |  | 2535 | 0 | 0 |
| KODIAK SCIENCES INC | Common Stock | 50015M109 |  | 4 | 532 | SH |  | SOLE |  | 532 | 0 | 0 |
| LEXICON PHARMACEUTICALS INC | Common Stock | 528872302 |  | 4 | 1918 | SH |  | SOLE |  | 1918 | 0 | 0 |
| MACROGENICS INC | Common Stock | 556099109 |  | 4 | 624 | SH |  | SOLE |  | 624 | 0 | 0 |
| NGM BIOPHARMACEUTICALS INC | Common Stock | 62921N105 |  | 4 | 830 | SH |  | SOLE |  | 830 | 0 | 0 |
| NEKTAR THERAPEUTICS | Common Stock | 640268108 |  | 4 | 1910 | SH |  | SOLE |  | 1910 | 0 | 0 |
| NANOSTRING TECHNOLOGIES INC | Common Stock | 63009R109 |  | 4 | 474 | SH |  | SOLE |  | 474 | 0 | 0 |
| PMV PHARMACEUTICALS INC | Common Stock | 69353Y103 |  | 4 | 464 | SH |  | SOLE |  | 464 | 0 | 0 |
| STOKE THERAPEUTICS INC | Common Stock | 86150R107 |  | 4 | 401 | SH |  | SOLE |  | 401 | 0 | 0 |
| TARSUS PHARMACEUTICALS INC | Common Stock | 87650L103 |  | 4 | 271 | SH |  | SOLE |  | 271 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | Common Stock | 880881107 |  | 4 | 383 | SH |  | SOLE |  | 383 | 0 | 0 |
| 2SEVENTY BIO INC | Common Stock | 901384107 |  | 4 | 386 | SH |  | SOLE |  | 386 | 0 | 0 |
| VANDA PHARMACEUTICALS INC | Common Stock | 921659108 |  | 4 | 575 | SH |  | SOLE |  | 575 | 0 | 0 |
| PEPSICO INC | Common Stock | 713448108 |  | 3 | 4 | SH |  | SOLE |  | 4 | 0 | 0 |
| STARBUCKS CORP | Common Stock | 855244109 |  | 3 | 26 | SH |  | SOLE |  | 26 | 0 | 0 |
| ALPINE IMMUNE SCIENCES INC | Common Stock | 02083G100 |  | 3 | 467 | SH |  | SOLE |  | 467 | 0 | 0 |
| ANNEXON INC | Common Stock | 03589W102 |  | 3 | 484 | SH |  | SOLE |  | 484 | 0 | 0 |
| ATARA BIOTHERAPEUTICS INC | Common Stock | 046513107 |  | 3 | 964 | SH |  | SOLE |  | 964 | 0 | 0 |
| BIOMEA FUSION INC | Common Stock | 09077A106 |  | 3 | 298 | SH |  | SOLE |  | 298 | 0 | 0 |
| C4 THERAPEUTICS INC | Common Stock | 12529R107 |  | 3 | 497 | SH |  | SOLE |  | 497 | 0 | 0 |
| CODEXIS INC | Common Stock | 192005106 |  | 3 | 668 | SH |  | SOLE |  | 668 | 0 | 0 |
| CONCERT PHARMACEUTICALS INC | Common Stock | 206022105 |  | 3 | 487 | SH |  | SOLE |  | 487 | 0 | 0 |
| FOGHORN THERAPEUTICS INC | Common Stock | 344174107 |  | 3 | 425 | SH |  | SOLE |  | 425 | 0 | 0 |
| GRITSTONE BIO INC | Common Stock | 39868T105 |  | 3 | 847 | SH |  | SOLE |  | 847 | 0 | 0 |
| G1 THERAPEUTICS INC | Common Stock | 3621LQ109 |  | 3 | 514 | SH |  | SOLE |  | 514 | 0 | 0 |
| CUE HEALTH INC | Common Stock | 229790100 |  | 3 | 1518 | SH |  | SOLE |  | 1518 | 0 | 0 |
| CENTURY THERAPEUTICS INC | Common Stock | 15673T100 |  | 3 | 599 | SH |  | SOLE |  | 599 | 0 | 0 |
| KINNATE BIOPHARMA INC | Common Stock | 49705R105 |  | 3 | 448 | SH |  | SOLE |  | 448 | 0 | 0 |
| KARYOPHARM THERAPEUTICS INC | Common Stock | 48576U106 |  | 3 | 825 | SH |  | SOLE |  | 825 | 0 | 0 |
| MEIRAGTX HOLDINGS PLC | Common Stock | G59665102 |  | 3 | 455 | SH |  | SOLE |  | 455 | 0 | 0 |
| NKARTA INC | Common Stock | 65487U108 |  | 3 | 496 | SH |  | SOLE |  | 496 | 0 | 0 |
| OMEGA THERAPEUTICS INC | Common Stock | 68217N105 |  | 3 | 488 | SH |  | SOLE |  | 488 | 0 | 0 |
| PHIBRO ANIMAL HEALTH CORP-A | Common Stock | 71742Q106 |  | 3 | 207 | SH |  | SOLE |  | 207 | 0 | 0 |
| PEPGEN INC | Common Stock | 713317105 |  | 3 | 240 | SH |  | SOLE |  | 240 | 0 | 0 |
| PETIQ INC | Common Stock | 71639T106 |  | 3 | 294 | SH |  | SOLE |  | 294 | 0 | 0 |
| PRECIGEN INC | Common Stock | 74017N105 |  | 3 | 2114 | SH |  | SOLE |  | 2114 | 0 | 0 |
| PAYPAL HOLDINGS INC | Common Stock | 70450Y103 |  | 2 | 34 | SH |  | SOLE |  | 34 | 0 | 0 |
| ACUMEN PHARMACEUTICALS INC | Common Stock | 00509G209 |  | 2 | 416 | SH |  | SOLE |  | 416 | 0 | 0 |
| ABSCI CORP | Common Stock | 00091E109 |  | 2 | 939 | SH |  | SOLE |  | 939 | 0 | 0 |
| ADAPTIMMUNE THERAPEUTICS-ADR | ADR | 00653A107 |  | 2 | 1469 | SH |  | SOLE |  | 1469 | 0 | 0 |
| AFFIMED NV | Common Stock | N01045108 |  | 2 | 1517 | SH |  | SOLE |  | 1517 | 0 | 0 |
| COMPASS PATHWAYS PLC | ADR | 20451W101 |  | 2 | 240 | SH |  | SOLE |  | 240 | 0 | 0 |
| CENTESSA PHARMACEUTICALS-ADR | ADR | 152309100 |  | 2 | 533 | SH |  | SOLE |  | 533 | 0 | 0 |
| EVELO BIOSCIENCES INC | Common Stock | 299734103 |  | 2 | 1113 | SH |  | SOLE |  | 1113 | 0 | 0 |
| EXSCIENTIA PLC | ADR | 30223G102 |  | 2 | 367 | SH |  | SOLE |  | 367 | 0 | 0 |
| GENERATION BIO CO | Common Stock | 37148K100 |  | 2 | 604 | SH |  | SOLE |  | 604 | 0 | 0 |
| GOSSAMER BIO INC | Common Stock | 38341P102 |  | 2 | 960 | SH |  | SOLE |  | 960 | 0 | 0 |
| GRACELL BIOTECHNOLOGIES-ADR | ADR | 38406L103 |  | 2 | 678 | SH |  | SOLE |  | 678 | 0 | 0 |
| GREENLIGHT BIOSCIENCES HOLDI | Common Stock | 39536G105 |  | 2 | 1539 | SH |  | SOLE |  | 1539 | 0 | 0 |
| GRAPHITE BIO INC | Common Stock | 38870X104 |  | 2 | 591 | SH |  | SOLE |  | 591 | 0 | 0 |
| HUMACYTE INC | Common Stock | 44486Q103 |  | 2 | 1047 | SH |  | SOLE |  | 1047 | 0 | 0 |
| I-MAB-SPONSORED ADR | ADR | 44975P103 |  | 2 | 553 | SH |  | SOLE |  | 553 | 0 | 0 |
| INVIVYD INC | Common Stock | 00534A102 |  | 2 | 1107 | SH |  | SOLE |  | 1107 | 0 | 0 |
| MARINUS PHARMACEUTICALS INC | Common Stock | 56854Q200 |  | 2 | 485 | SH |  | SOLE |  | 485 | 0 | 0 |
| NAUTILUS BIOTECHNOLOGY INC | Common Stock | 63909J108 |  | 2 | 1267 | SH |  | SOLE |  | 1267 | 0 | 0 |
| OCULAR THERAPEUTIX INC | Common Stock | 67576A100 |  | 2 | 782 | SH |  | SOLE |  | 782 | 0 | 0 |
| OPTINOSE INC | Common Stock | 68404V100 |  | 2 | 1116 | SH |  | SOLE |  | 1116 | 0 | 0 |
| PRELUDE THERAPEUTICS INC | Common Stock | 74065P101 |  | 2 | 370 | SH |  | SOLE |  | 370 | 0 | 0 |
| QUANTUM-SI INC | Common Stock | 74765K105 |  | 2 | 1218 | SH |  | SOLE |  | 1218 | 0 | 0 |
| SELECTA BIOSCIENCES INC | Common Stock | 816212104 |  | 2 | 1554 | SH |  | SOLE |  | 1554 | 0 | 0 |
| ALAUNOS THERAPEUTICS INC | Common Stock | 98973P101 |  | 2 | 2442 | SH |  | SOLE |  | 2442 | 0 | 0 |
| UROGEN PHARMA LTD | Common Stock | M96088105 |  | 2 | 234 | SH |  | SOLE |  | 234 | 0 | 0 |
| XERIS BIOPHARMA HOLDINGS INC | Common Stock | 98422E103 |  | 2 | 1381 | SH |  | SOLE |  | 1381 | 0 | 0 |
| WALMART INC | Common Stock | 931142103 |  | 1 | 5 | SH |  | SOLE |  | 5 | 0 | 0 |
| EIGER BIOPHARMACEUTICALS INC | Common Stock | 28249U105 |  | 1 | 447 | SH |  | SOLE |  | 447 | 0 | 0 |
| IMMUNEERING CORP - CLASS A | Common Stock | 45254E107 |  | 1 | 268 | SH |  | SOLE |  | 268 | 0 | 0 |
| OMEROS CORP | Common Stock | 682143102 |  | 1 | 637 | SH |  | SOLE |  | 637 | 0 | 0 |
| INSTIL BIO INC | Common Stock | 45783C101 |  | 1 | 1318 | SH |  | SOLE |  | 1318 | 0 | 0 |
| SEA LTD-ADR | ADR | 81141R100 |  | 0 | 8 | SH |  | SOLE |  | 8 | 0 | 0 |

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