# EDGAR Filing Document

**Accession Number:** 0001426800
**File Stem:** 0000000000-23-002955
**Filing Date:** 2023-3
**Character Count:** 3506
**Document Hash:** 40a37817d96f83392e2f781cbe8732fe
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000000000-23-002955.hdr.sgml**: 20230512

**ACCESSION NUMBER**: 0000000000-23-002955

**CONFORMED SUBMISSION TYPE**: UPLOAD

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20230324

**FILED FOR**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ASSEMBLY BIOSCIENCES, INC.
- **CENTRAL INDEX KEY:** 0001426800
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** UPLOAD

**BUSINESS ADDRESS:**
- **STREET 1:** 331 OYSTER POINT BLVD.
- **STREET 2:** FOURTH FLOOR
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080
- **BUSINESS PHONE:** (833) 409-4583

**MAIL ADDRESS:**
- **STREET 1:** 331 OYSTER POINT BLVD.
- **STREET 2:** FOURTH FLOOR
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VENTRUS BIOSCIENCES INC
- **DATE OF NAME CHANGE:** 20080211
**PUBLIC REFERENCE ACCESSION NUMBER**: 0001193125-23-076827

## Text-Extract

```

United States securities and exchange commission logo

                          March 24, 2023

       Jason Okazaki
       Chief Executive Officer
       Assembly Biosciences, Inc.
       331 Oyster Point Blvd., Fourth Floor
       South San Francisco, CA 94080

                                                        Re: Assembly
Biosciences, Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed March 22,
2023
                                                            File No. 333-270760

       Dear Jason Okazaki:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jason
Drory at 202-551-8342 with any questions.

                          Sincerely,

                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              P. Michelle Gasaway

```

### Attached PDF Documents

**Attachment 1:** `filename1`

![img-0.jpeg](img-0.jpeg)

DIVISION OF
CORPORATION FINANCE

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

March 24, 2023

Jason Okazaki
Chief Executive Officer
Assembly Biosciences, Inc.
331 Oyster Point Blvd., Fourth Floor
South San Francisco, CA 94080

**Re: Assembly Biosciences, Inc.**
**Registration Statement on Form S-3**
**Filed March 22, 2023**
**File No. 333-270760**

Dear Jason Okazaki:

This is to advise you that we have not reviewed and will not review your registration statement.

Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff.

Please contact Jason Drory at 202-551-8342 with any questions.

Sincerely,

Division of Corporation Finance
Office of Life Sciences

cc: P. Michelle Gasaway