# EDGAR Filing Document

**Accession Number:** 0001080014
**File Stem:** 0001104659-25-107014
**Filing Date:** 2025-11
**Character Count:** 25437
**Document Hash:** e5a965f72a6d8dbb82ec13abe685e933
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-107014.hdr.sgml**: 20251105

**ACCESSION NUMBER**: 0001104659-25-107014

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 14

**CONFORMED PERIOD OF REPORT**: 20251105

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20251105

**DATE AS OF CHANGE**: 20251105

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Innoviva, Inc.
- **CENTRAL INDEX KEY:** 0001080014
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 943265960
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30319
- **FILM NUMBER:** 251454305

**BUSINESS ADDRESS:**
- **STREET 1:** 1350 OLD BAYSHORE HIGHWAY
- **STREET 2:** SUITE 400
- **CITY:** BURLINGAME
- **STATE:** CA
- **ZIP:** 94010
- **BUSINESS PHONE:** 6502389600

**MAIL ADDRESS:**
- **STREET 1:** 1350 OLD BAYSHORE HIGHWAY
- **STREET 2:** SUITE 400
- **CITY:** BURLINGAME
- **STATE:** CA
- **ZIP:** 94010

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** THERAVANCE INC
- **DATE OF NAME CHANGE:** 20020207

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ADVANCED MEDICINE INC
- **DATE OF NAME CHANGE:** 20000302

?xml version='1.0' encoding='ASCII'?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, DC 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934**

Date of Report (Date of earliest event reported): **November 5, 2025**

**INNOVIVA, INC.**

(Exact Name of Registrant as Specified in its Charter)

---

| | | |
|:---|:---|:---|
| **Delaware** | **000-30319** | **94-3265960** |
| (State or Other Jurisdiction of <br> Incorporation) | (Commission File Number) | (I.R.S. Employer Identification <br> Number) |

---

**1350 Old Bayshore Highway** **, Suite 400**

**Burlingame** **, California 94010**

**(650) 238-9600**

(Addresses, including zip code, and telephone numbers, including area code, of principal executive offices)

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

---

| | |
|:---|:---|
| &nbsp;&nbsp;&nbsp;◻ | &nbsp;&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
| &nbsp;&nbsp;&nbsp;◻ | &nbsp;&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
| &nbsp;&nbsp;&nbsp;◻ | &nbsp;&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
| &nbsp;&nbsp;&nbsp;◻ | &nbsp;&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |

---

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| &nbsp;&nbsp;Title of each class | &nbsp;&nbsp;Trading Symbol(s) | &nbsp;&nbsp;Name of each exchange on which registered |
| &nbsp;&nbsp;Common Stock, par value $0.01 per share | &nbsp;&nbsp;INVA | &nbsp;&nbsp;The NASDAQ Global Select Market |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933(§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ◻

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ◻

**Item 2.02. Results of Operations and Financial Condition**

On November 5, 2025, Innoviva, Inc. (the "Company") issued a press release regarding its results of operations and financial condition for the quarter ended September 30, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report.

The information in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, is being furnished and shall not be deemed "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

**Item 9.01. Financial Statements and Exhibits**

**(d) Exhibits**

[99.1](tm2530226d1_ex99-1.htm) [Press Release dated November 5, 2025](tm2530226d1_ex99-1.htm) <br> 104 Cover Page Interactive File (the cover page tags are embedded within the Inline XBRL document)

**SIGNATURE**

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  | **INNOVIVA, INC.** | **INNOVIVA, INC.** |
| Date: November 5, 2025 | By: | /s/ Pavel Raifeld |
|  |  | **Pavel Raifeld** |
|  |  | **Chief Executive Officer** |

---

## Exhibit 99.1

**Exhibit 99.1**

![](tm2530226d1_ex99-1img001.jpg)

**Innoviva Reports Third Quarter 2025 Financial Results; Highlights Recent Company Progress**

*Generated $63.4 million in revenue from durable royalties portfolio*

 

*IST achieved U.S. net product sales of $29.9 million, representing 52% year-over-year growth*

 

*Strengthened product portfolio with U.S. launch of ZEVTERA*<sup>®</sup>

*Announced $125 million share repurchase program*

**BURLINGAME, Calif. – November 5, 2025** – Innoviva, Inc. (NASDAQ: INVA) ("Innoviva" or the "Company"), a diversified holding company with a core royalties portfolio, a leading critical care and infectious disease platform known as Innoviva Specialty Therapeutics ("IST"), and a portfolio of strategic investments in healthcare assets, today reported financial results for the third quarter ended September 30, 2025, and highlighted select corporate progress and achievements.

"Innoviva delivered strong third-quarter performance across each area of our business. The royalties portfolio reaffirmed its resilience with 5% growth compared to last year, while IST delivered a third consecutive quarter of greater than 50% year-over-year U.S. sales growth. We are encouraged by early market receptivity for ZEVTERA<sup>®</sup> following its U.S. launch over the summer and look forward to zoliflodacin's December 15 PDUFA date," said Pavel Raifeld, Chief Executive Officer of Innoviva.

"Across the broader portfolio, we saw meaningful value creation from our strategic investments, including Armata Pharmaceuticals, and continued to thoughtfully deploy capital in areas of opportunity and market dislocation. The $125 million share repurchase program underscores our confidence in Innoviva's prospects, supported by the strength of our balance sheet and cashflows, as we strive to create value for our shareholders," concluded Mr. Raifeld.

**Financial Highlights**

&nbsp;&nbsp;&nbsp;&nbsp;· **Total revenue:** Total revenue for the third quarter 2025 was $107.8 million, representing 20%
 growth compared to total revenue of $89.5 million for the third quarter 2024.

&nbsp;&nbsp;&nbsp;&nbsp;· **Royalty revenue:** Third quarter 2025 gross royalty revenue
from Glaxo Group Limited ("GSK") was $63.4 million, compared to $60.5 million for the third quarter
2024. &nbsp;&nbsp;&nbsp;&nbsp;· **Net product sales:** Third quarter 2025 net product sales
totaled $47.3 million, consisting of $29.9 million in U.S. net product sales and $17.4 million in ex-U.S. net
product sales, compared to $27.8 million in net product sales for the third quarter 2024. U.S. net product sales included $18.2
million from GIAPREZA<sup>®</sup>, $8.5 million from XACDURO<sup>®</sup>, $3.2 million from XERAVA<sup>®</sup>,
and $0.1 million from ZEVTERA<sup>®</sup>, representing a 52% increase compared to total U.S. net product sales
of $19.7 million in the third quarter 2024.

![](tm2530226d1_ex99-1img001.jpg)

&nbsp;&nbsp;&nbsp;&nbsp;· **Income from operations:** Third quarter 2025 income from
operations was $34.6 million, a 20% decrease from $43.2 million in the third quarter 2024, primarily due to a non-recurring
expense related to research and development.

&nbsp;&nbsp;&nbsp;&nbsp;· **Equity and long-term investments:** Third quarter 2025
net favorable changes in fair values of equity and long-term investments totaled $62.3 million, compared to unfavorable changes of $35.2
million in the third quarter 2024, were primarily due to share price appreciation of Armata Pharmaceuticals and other equity investments.

&nbsp;&nbsp;&nbsp;&nbsp;· **Net income:** Third quarter 2025 net income was $89.9
million, or $1.30 basic per share, compared to a net income of $1.2 million, or $0.02 basic per share, for the third quarter
2024. &nbsp;&nbsp;&nbsp;&nbsp;· **Cash and cash equivalents:** Totaled $476.5 million.
Royalty and net product sales receivables totaled $93.5 million as of September 30, 2025.

**Key Business and R&D Highlights**

&nbsp;&nbsp;&nbsp;&nbsp;· **Zoliflodacin:** an investigational, first-in-class, single oral dose, spiropyrimidinetrione antibiotic for the treatment
of uncomplicated gonorrhea in adults and pediatric patients 12 years and older. It is being developed in partnership with The Global
Antibiotic Research & Development Partnership ("GARDP").

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o In October 2025, IST, in collaboration with GARDP, presented three sets of data highlighting key subgroup analyses
 from the pivotal Phase 3 trial for zoliflodacin at the Infectious Disease Society of America's IDWeek 2025 annual
 meeting.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o Zoliflodacin is currently under Priority Review by the U.S. Food and Drug Administration (FDA), with a Prescription Drug User Fee
Act (PDUFA) target action date of December 15, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o Subsequent to the New Drug Application (NDA) acceptance in June 2025, the FDA indicated in its Day-74 letter that it did not
plan to hold an Advisory Committee meeting to discuss the zoliflodacin NDA.

&nbsp;&nbsp;&nbsp;&nbsp;· **ZEVTERA** <sup>®</sup> **(ceftobiprole):** an advanced-generation cephalosporin antibiotic approved in the U.S. for
three specific indications – *Staphylococcus aureus* bloodstream infections (bacteremia) (SAB) in adults, including
right-sided infective endocarditis, acute bacterial skin and skin structure infections (ABSSSI) in adults, and community-acquired bacterial
pneumonia (CABP) in adults and pediatric patients (3 months to less than 18 years old).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o In July 2025, IST commercially launched ZEVTERA<sup>®</sup> in the U.S. Initial launch activity has been focused
on formulary committee engagement and market access programs.

&nbsp;&nbsp;&nbsp;&nbsp;· Both
 ZEVTERA<sup>®</sup> (ceftobiprole) and XACDURO<sup>®</sup> (sulbactam for injection;
 durlobactam for injection) were recently nominated for the 2025 Prix Galien USA Award for
 Best Pharmaceutical Product by the Galien Foundation, one of the most prestigious honors
 in the biopharmaceutical and medical technology fields, celebrating groundbreaking achievements
 that drive meaningful progress.

&nbsp;&nbsp;&nbsp;&nbsp;· **Capital Allocation** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o Innoviva's portfolio of strategic assets held through the Company's various subsidiaries was valued at $483.0 million as
of September 30, 2025.

![](tm2530226d1_ex99-1img001.jpg)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o Innoviva's Board of Directors has authorized a new share repurchase program under which the Company may repurchase up to $125.0
million of its outstanding shares of common stock. The timing and amount of any share repurchases under the share repurchase program will be subject to the Securities and Exchange Commission
Rule 10b-18 and Rule 10b5-1 requirements and will be determined by Innoviva's management in its discretion based on ongoing assessments
of the capital needs of the business, the market price of Innoviva's common stock, prevailing stock prices, general market conditions,
and other considerations. Share repurchases under the program may be made through a variety of methods, which may include open market
purchases, privately negotiated transactions, in block trades, accelerated share repurchase transactions, exchange transactions, or any
combination thereof or by other means in accordance with federal securities laws. This program has no termination date, may be suspended
or discontinued at any time at the Company's discretion, and does not obligate the Company to acquire any amount of common stock.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o In August 2025, a substantial portion of the Company's 2025 convertible noteholders elected to convert an aggregate principal
balance of $192.5 million into 11.1 million shares of Innoviva common stock prior to maturity.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o In August 2025, Innoviva invested $15.0 million in a term loan to Armata Pharmaceuticals, which recently announced positive
Phase 2 data in *Staphylococcus aureus* bacteremia.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o In September 2025, Innoviva acquired a proprietary long-acting oral drug delivery platform and related assets from Lyndra
Therapeutics, Inc. The transaction included an upfront payment of $10.2 million, plus potential milestone and royalty payments.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o In October 2025, Innoviva invested $17.5 million in the Series B Preferred Stock of Beacon Biosignals, Inc., an
AI-driven neurotechnology company developing treatments for neurological, psychiatric, and sleep disorders.

**About Innoviva**

Innoviva is a diversified holding company with a core royalties portfolio, a leading critical care and infectious disease platform known as Innoviva Specialty Therapeutics ("IST"), and a portfolio of strategic investments in healthcare assets. Innoviva's royalty portfolio includes respiratory assets partnered with Glaxo Group Limited ("GSK"). Innoviva is entitled to receive royalties from GSK on sales of RELVAR<sup>®</sup>/BREO<sup>®</sup> ELLIPTA<sup>®</sup> and ANORO<sup>®</sup> ELLIPTA<sup>®</sup>. Innoviva's other innovative healthcare assets include infectious disease and critical care assets stemming from acquisitions of Entasis Therapeutics, including XACDURO<sup>®</sup> (sulbactam for injection; durlobactam for injection), co-packaged for intravenous use approved for the treatment of adults with hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible strains of Acinetobacter baumannii-calcoaceticus complex and the investigational zoliflodacin currently being developed for the treatment of uncomplicated gonorrhea, and La Jolla Pharmaceutical Company, including GIAPREZA<sup>®</sup> (angiotensin II), approved to increase blood pressure in adults with septic or other distributive shock and XERAVA<sup>®</sup> (eravacycline) for the treatment of complicated intra-abdominal infections in adults. Innoviva also markets ZEVTERA (ceftobiprole), an advanced-generation cephalosporin antibiotic, in the U.S. through an exclusive license from Basilea Pharmaceutica International Ltd, Allschwil. For more information about Innoviva, go to www.inva.com. For information about Innoviva Specialty Therapeutics, go to <u>www.innovivaspecialtytherapeutics.com</u>.

ANORO<sup>®</sup>, RELVAR<sup>®</sup> and BREO<sup>®</sup> are trademarks of the GSK group of companies. ZEVTERA is a trademark of Basilea Pharmaceutica Ltd, Allschwil.

![](tm2530226d1_ex99-1img001.jpg)

**Forward Looking Statements**

This press release contains certain "forward-looking" statements as that term is defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans, objectives, and future events. Innoviva intends such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. The words "anticipate", "expect", "goal", "intend", "objective", "opportunity", "plan", "potential", "target" and similar expressions are intended to identify such forward-looking statements. Such forward-looking statements involve substantial risks, uncertainties, and assumptions. These statements are based on the current estimates and assumptions of the management of Innoviva as of the date of this press release and are subject to known and unknown risks, uncertainties, changes in circumstances, assumptions and other factors that may cause the actual results of Innoviva to be materially different from those reflected in the forward-looking statements. Important factors that could cause actual results to differ materially from those indicated by such forward-looking statements include, among others, risks related to: expected cost savings; lower than expected future royalty revenue from respiratory products partnered with GSK; the commercialization of RELVAR<sup>®</sup>/BREO<sup>®</sup> ELLIPTA<sup>®</sup>, ANORO<sup>®</sup> ELLIPTA<sup>®</sup>, GIAPREZA<sup>®</sup>, XERAVA<sup>®</sup>, XACDURO<sup>®</sup> and ZEVTERA<sup>®</sup> in the jurisdictions in which these products have been approved; the strategies, plans and objectives of Innoviva (including Innoviva's growth strategy and corporate development initiatives); the timing, manner, and amount of potential capital returns to shareholders; the status and timing of clinical studies, data analysis and communication of results; the potential benefits and mechanisms of action of product candidates; expectations for product candidates through development and commercialization; the timing of regulatory approval of product candidates; and projections of revenue, expenses and other financial items; the timing, manner and amount of capital deployment, including potential capital returns to stockholders; and risks related to the Company's growth strategy. Other risks affecting Innoviva are described under the headings "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" contained in Innoviva's Annual Report on Form 10-K for the year ended December 31, 2024 and subsequently Quarterly Reports on Form 10-Q, which are on file with the Securities and Exchange Commission ("SEC") and available on the SEC's website at www.sec.gov. Past performance is not necessarily indicative of future results. No forward-looking statements can be guaranteed, and actual results may differ materially from such statements. Given these uncertainties, you should not place undue reliance on these forward-looking statements. The information in this press release is provided only as of the date hereof, and Innoviva assumes no obligation to update its forward-looking statements on account of new information, future events or otherwise, except as required by law.

![](tm2530226d1_ex99-1img001.jpg)

INNOVIVA, INC.

Condensed Consolidated Statements of Income

(in thousands, except per share data)

(Unaudited)

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | Three Months Ended | Three Months Ended | Nine Months Ended | Nine Months Ended |
|  | September 30, | September 30, | September 30, | September 30, |
|  | 2025 | 2024 | 2025 | 2024 |
| Revenue: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Royalty revenue, net (1) | $59896 | $57056 | $181583 | $179213 |
| &nbsp;&nbsp;&nbsp;Net product sales | 47294 | 27822 | 113066 | 68557 |
| &nbsp;&nbsp;&nbsp;License and other revenue | 610 | 4630 | 2066 | 19135 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total revenue | 107800 | 89508 | 296715 | 266905 |
| Cost of products sold (inclusive of amortization of inventory fair value adjustments) | 25643 | 9990 | 45075 | 29433 |
| Amortization of acquired intangible assets | 6618 | 6511 | 19640 | 19391 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Gross profit | 75539 | 73007 | 232000 | 218081 |
| Operating expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Selling, general and administrative | 27291 | 26219 | 81194 | 84364 |
| &nbsp;&nbsp;&nbsp;Research and development | 13670 | 3551 | 26049 | 9989 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | 40961 | 29770 | 107243 | 94353 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Income from operations | 34578 | 43237 | 124757 | 123728 |
| Changes in fair values of equity method investments, net | 30751 | (18231) | 30284 | (42997) |
| Changes in fair values of equity and long-term investments, net | 31510 | (16936) | (22509) | (60827) |
| Interest and dividend income | 5472 | 5500 | 14935 | 13373 |
| Interest expense | (4015) | (5807) | (13389) | (17460) |
| Other expense, net | (479) | (914) | (2252) | (3123) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Income (loss) before income taxes | 97817 | 6849 | 131826 | 12694 |
| Income tax expense | (7909) | (5636) | (24814) | (9634) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net income (loss) | $89908 | $1213 | $107012 | $3060 |
| Net income (loss) per share: |  |  |  |  |
| Basic | $1.30 | $0.02 | $1.65 | $0.05 |
| Diluted | $1.08 | $0.02 | $1.35 | $0.05 |
| Shares used to compute net income (loss) per share: |  |  |  |  |
| Basic | 69058 | 62569 | 64901 | 62759 |
| Diluted | 84964 | 62951 | 84576 | 63020 |

---

(1) Total net revenue is comprised of the following (in thousands):

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | Three Months Ended | Three Months Ended | Nine Months Ended | Nine Months Ended |
|  | September 30, | September 30, | September 30, | September 30, |
|  | 2025 | 2024 | 2025 | 2024 |
|  | (unaudited) | (unaudited) | (unaudited) | (unaudited) |
| Royalties | $63352 | $60512 | $191951 | $189581 |
| Amortization of capitalized fees | (3456) | (3456) | (10368) | (10368) |
| &nbsp;&nbsp;&nbsp;Royalty revenue, net | $59896 | $57056 | $181583 | $179213 |

---

![](tm2530226d1_ex99-1img001.jpg)

INNOVIVA, INC.

Condensed Consolidated Balance Sheets

(in thousands)

(unaudited)

---

| | | |
|:---|:---|:---|
|  | September 30,<br>2025 | December 31,<br>2024 |
| Assets |  |  |
| &nbsp;&nbsp;&nbsp;Cash and cash equivalents | $476513 | $304964 |
| &nbsp;&nbsp;&nbsp;Royalty and product sale receivables | 93519 | 86366 |
| &nbsp;&nbsp;&nbsp;Inventory, net | 38363 | 33725 |
| &nbsp;&nbsp;&nbsp;Prepaid expense and other current assets | 19586 | 21719 |
| &nbsp;&nbsp;&nbsp;Current portion of ISP Fund investments | 56589 | 107532 |
| &nbsp;&nbsp;&nbsp;Property and equipment, net | 1529 | 514 |
| &nbsp;&nbsp;&nbsp;Equity method and equity and long-term investments | 426371 | 393957 |
| &nbsp;&nbsp;&nbsp;Capitalized fees | 59593 | 69961 |
| &nbsp;&nbsp;&nbsp;Right-of-use assets | 1402 | 2453 |
| &nbsp;&nbsp;&nbsp;Goodwill | 17905 | 17905 |
| &nbsp;&nbsp;&nbsp;Intangible assets | 188793 | 208433 |
| &nbsp;&nbsp;&nbsp;Deferred tax assets | 7982 | 12054 |
| &nbsp;&nbsp;&nbsp;Other assets | 40961 | 41477 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total assets | $1429106 | $1301060 |
| Liabilities and stockholders' equity |  |  |
| &nbsp;&nbsp;&nbsp;Other current liabilities | $34669 | $39507 |
| &nbsp;&nbsp;&nbsp;Accrued interest payable | 231 | 3422 |
| &nbsp;&nbsp;&nbsp;Deferred revenues | 13571 | 1126 |
| &nbsp;&nbsp;&nbsp;Convertible senior notes, due 2025, net |  | 192028 |
| &nbsp;&nbsp;&nbsp;Convertible senior notes, due 2028, net | 257377 | 256316 |
| &nbsp;&nbsp;&nbsp;Other long term liabilities | 57431 | 64275 |
| &nbsp;&nbsp;&nbsp;Income tax payable - long term | 55876 | 53227 |
| &nbsp;&nbsp;&nbsp;Innoviva stockholders' equity | 1009951 | 691159 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total liabilities and stockholders' equity | $1429106 | $1301060 |

---

Cash Flows Summary

(in thousands)

(unaudited)

---

| | | |
|:---|:---|:---|
|  | Nine Months Ended September 30, | Nine Months Ended September 30, |
|  | 2025 | 2024 |
| Net cash provided by operating activities | $142417 | $129451 |
| Net cash provided by (used in) investing activities | 16860 | (48308) |
| Net cash provided by (used in) financing activities | 12272 | (14026) |
| Net change | $171549 | $67117 |
| Cash and cash equivalents at beginning of period | 304964 | 193513 |
| Cash and cash equivalents at end of period | $476513 | $260630 |

---

![](tm2530226d1_ex99-1img001.jpg)

**Contacts**

Innoviva, Inc.

David Patti

Corporate Communications

(908) 421-5971

<u>david.patti@inva.com</u>

Investors and Media:

Argot Partners<br> (212) 600-1902<br> <u>innoviva@argotpartners.com</u>