# EDGAR Filing Document

**Accession Number:** 0002006986
**File Stem:** 0001104659-25-119990
**Filing Date:** 2025-12
**Character Count:** 2962
**Document Hash:** d66ad69ec2d4782c29bb88267be2dba5
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-119990.hdr.sgml**: 20260522

**ACCESSION NUMBER**: 0001104659-25-119990

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20251210

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Adagio Medical Holdings, Inc.
- **CENTRAL INDEX KEY:** 0002006986
- **STANDARD INDUSTRIAL CLASSIFICATION:** SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 26051 MERIT CIRCLE
- **STREET 2:** SUITE 102
- **CITY:** LAGUNA HILLS
- **STATE:** CA
- **ZIP:** 92653
- **BUSINESS PHONE:** (949) 348-1188

**MAIL ADDRESS:**
- **STREET 1:** 26051 MERIT CIRCLE
- **STREET 2:** SUITE 102
- **CITY:** LAGUNA HILLS
- **STATE:** CA
- **ZIP:** 92653

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Aja Holdco, Inc.
- **DATE OF NAME CHANGE:** 20240104

**Adagio Medical Holdings, I** **NC.** 

26051 Merit Circle, Suite 102

Laguna Hills, CA 92653

December 10, 2025

Via EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

---

| | |
|:---|:---|
| Re: | **A** **dagio Medical Holdings, Inc.** |
|  | **Registration Statement on Form S-3 (File No. 333-291741)** |
|  | **Request for Acceleration of Effective Date** |

---

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant (the "***Registrant***") hereby requests that the Securities and Exchange Commission (the "***Commission***") take appropriate action to cause the above-referenced Registration Statement on Form S-3 (File No. 333-291741) (the "***Registration Statement***") to become effective on December 12, 2025, at 4:00 p.m. Eastern Time, or as soon thereafter as is practicable, or at such other time as the Registrant or its legal counsel, Cooley LLP, may request by telephone to the staff of the Commission. The Registrant hereby authorizes each of Eric Blanchard and Paul Alexander of Cooley LLP to make such a request on its behalf.

Once the Registration Statement has been declared effective, please confirm that event with Eric Blanchard of Cooley LLP, counsel to the Registrant, at (617) 937-2445 or eblanchard@cooley.com, or in his absence, Paul Alexander, at (202) 776-2118 or palexander@cooley.com.

*[Signature page follows]* 

---

| | |
|:---|:---|
| Very truly yours, | Very truly yours, |
| Adagio Medical Holdings, Inc. | Adagio Medical Holdings, Inc. |
| By: | /s/ Deborah Kaster |
|  | Deborah Kaster |
|  | *Chief Financial Officer and Chief Business Officer* |

---

cc: Todd Usen, Adagio Medical Holdings, Inc. <br> Eric Blanchard, Cooley LLP <br> Paul Alexander, Cooley LLP

 

*Signature Page to Company Acceleration Request – S-3*