# EDGAR Filing Document

**Accession Number:** 0001861657
**File Stem:** 0001493152-23-008531
**Filing Date:** 2023-3
**Character Count:** 2064
**Document Hash:** d4b0077a578f01557930b7813d1afd59
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001493152-23-008531.hdr.sgml**: 20230421

**ACCESSION NUMBER**: 0001493152-23-008531

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230322

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Hillstream BioPharma Inc.
- **CENTRAL INDEX KEY:** 0001861657
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 842642541
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 1200 ROUTE 22 EAST
- **CITY:** BRIDGEWATER
- **STATE:** NJ
- **ZIP:** 08807
- **BUSINESS PHONE:** 302-743-2995

**MAIL ADDRESS:**
- **STREET 1:** 245 MAIN STREET
- **STREET 2:** SUITE 204
- **CITY:** CHESTER
- **STATE:** NJ
- **ZIP:** 07930

**Hillstream BioPharma, Inc.**

**1200 Route 22 East, Suite 2000**

**Bridgewater, NJ 08807**

March 22, 2023

**<u>VIA EDGAR</u>**

United States Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Attention: Arzhang Navai

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| | |
|:---|:---|
| **Re:** | **Hillstream BioPharma, Inc.** |
|  | **Registration Statement on Form S-3** |
|  | **File No. 333-270684** |

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Ladies and Gentlemen:

Pursuant to Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended, Hillstream BioPharma, Inc. (the "Company") respectfully requests that the effective date of the registration statement referred to above be accelerated so that it will become effective at 4:30 p.m., Eastern Standard Time, on Friday, March 24, 2023, or as soon thereafter as possible.

Please notify Nazia Khan of Sheppard, Mullin, Richter & Hampton LLP, counsel to the Company, at (202) 747-2651 as soon as possible as to the time the Registration Statement has been declared effective pursuant to this acceleration request.

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| | |
|:---|:---|
| HILLSTREAM BIOPHARMA, INC. | HILLSTREAM BIOPHARMA, INC. |
| By: | */s/ Randy Milby* |
| Name: | Randy Milby |
| Title: | Chief Executive Officer |

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