# EDGAR Filing Document

**Accession Number:** 0001335325
**File Stem:** 0001172661-26-000882
**Filing Date:** 2026-2
**Character Count:** 18110
**Document Hash:** 2286303dc2fa00eb44b54c9a491c8f63
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001172661-26-000882.hdr.sgml**: 20260217

**ACCESSION NUMBER**: 0001172661-26-000882

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260217

**DATE AS OF CHANGE**: 20260217

**EFFECTIVENESS DATE**: 20260217

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** HighVista Strategies LLC
- **CENTRAL INDEX KEY:** 0001335325

**ORGANIZATION NAME:**
- **EIN:** 830423786
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-14212
- **FILM NUMBER:** 26637338

**BUSINESS ADDRESS:**
- **STREET 1:** 200 CLARENDON STREET, 50TH FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116
- **BUSINESS PHONE:** 617-406-6500

**MAIL ADDRESS:**
- **STREET 1:** 200 CLARENDON STREET, 50TH FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** HighVista Strategies LLC<br>**Address:** 200 CLARENDON STREET 50TH FLOOR<br>BOSTON, MA 02116

**Form 13F File Number:** 028-14212

**CRD Number (if applicable):** 000155759

**SEC File Number (if applicable):** 801-73524

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Nicholas Boston<br>**Title:** Chief Compliance Officer<br>**Phone:** 617-406-6546

**Signature, Place, and Date of Signing:**

/s/ Nicholas Boston  Boston, MA  02-17-2026<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 1

**Form 13F Information Table Entry Total:** 145

**Form 13F Information Table Value Total:** $388309219

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

| No.   | Name                                     | Form 13F File Number   |
|:---|:---|:---|
|  | HighVista Private Capital Management LLC |  |

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 3M CO | COM | 88579Y101 |  | 632395 | 3950 | SH |  | SOLE |  | 3950 | 0 | 0 |
| ABIVAX SA | SPONSORED ADS | 00370M103 |  | 9734508 | 72185 | SH |  | SOLE |  | 72185 | 0 | 0 |
| ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 |  | 1158329 | 81630 | SH |  | SOLE |  | 81630 | 0 | 0 |
| AFFIRM HLDGS INC | COM CL A | 00827B106 |  | 973991 | 13086 | SH |  | SOLE |  | 13086 | 0 | 0 |
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 |  | 4019360 | 147662 | SH |  | SOLE |  | 147662 | 0 | 0 |
| ALCON AG | ORD SHS | H01301128 |  | 660643 | 10440 | SH |  | SOLE |  | 10440 | 0 | 0 |
| ALKERMES PLC | SHS | G01767105 |  | 738700 | 26401 | SH |  | SOLE |  | 26401 | 0 | 0 |
| ALPHABET INC | CAP STK CL C | 02079K107 |  | 1969723 | 6277 | SH |  | SOLE |  | 6277 | 0 | 0 |
| AMAZON COM INC | COM | 023135106 |  | 4015575 | 17397 | SH |  | SOLE |  | 17397 | 0 | 0 |
| AMPHENOL CORP NEW | CL A | 032095101 |  | 956926 | 7081 | SH |  | SOLE |  | 7081 | 0 | 0 |
| AMRIZE LTD | SHS | H2927K103 |  | 1809949 | 33468 | SH |  | SOLE |  | 33468 | 0 | 0 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 |  | 2884849 | 238812 | SH |  | SOLE |  | 238812 | 0 | 0 |
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 |  | 3787493 | 150776 | SH |  | SOLE |  | 150776 | 0 | 0 |
| API GROUP CORP | COM STK | 00187Y100 |  | 1184453 | 30958 | SH |  | SOLE |  | 30958 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 6735005 | 89229 | SH |  | SOLE |  | 89229 | 0 | 0 |
| APPLOVIN CORP | COM CL A | 03831W108 |  | 1672422 | 2482 | SH |  | SOLE |  | 2482 | 0 | 0 |
| ARCELLX INC | COMMON STOCK | 03940C100 |  | 4890130 | 75002 | SH |  | SOLE |  | 75002 | 0 | 0 |
| ARGAN INC | COM | 04010E109 |  | 594055 | 1896 | SH |  | SOLE |  | 1896 | 0 | 0 |
| ARGENX SE | SPONSORED ADR | 04016X101 |  | 3017329 | 3588 | SH |  | SOLE |  | 3588 | 0 | 0 |
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 |  | 780458 | 3660 | SH |  | SOLE |  | 3660 | 0 | 0 |
| AUTOLIV INC | COM | 052800109 |  | 622344 | 5243 | SH |  | SOLE |  | 5243 | 0 | 0 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 |  | 1736659 | 95631 | SH |  | SOLE |  | 95631 | 0 | 0 |
| AVIDITY BIOSCIENCES INC | COM | 05370A108 |  | 2886643 | 40020 | SH |  | SOLE |  | 40020 | 0 | 0 |
| AXSOME THERAPEUTICS INC | COM | 05464T104 |  | 2032965 | 11131 | SH |  | SOLE |  | 11131 | 0 | 0 |
| BANCO BRADESCO S A | SP ADR PFD NEW | 059460303 |  | 633579 | 190264 | SH |  | SOLE |  | 190264 | 0 | 0 |
| BOOKING HOLDINGS INC | COM | 09857L108 |  | 1301346 | 243 | SH |  | SOLE |  | 243 | 0 | 0 |
| BRIDGEBIO ONCOLOGY THERAPEUT | COM NEW | 107924102 |  | 2870372 | 229263 | SH |  | SOLE |  | 229263 | 0 | 0 |
| BRIDGEBIO PHARMA INC | COM | 10806X102 |  | 6134880 | 80205 | SH |  | SOLE |  | 80205 | 0 | 0 |
| BROADCOM INC | COM | 11135F101 |  | 1951658 | 5639 | SH |  | SOLE |  | 5639 | 0 | 0 |
| CELCUITY INC | COM | 15102K100 |  | 1649999 | 16543 | SH |  | SOLE |  | 16543 | 0 | 0 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 |  | 1407024 | 51805 | SH |  | SOLE |  | 51805 | 0 | 0 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 |  | 1112695 | 44490 | SH |  | SOLE |  | 44490 | 0 | 0 |
| CG ONCOLOGY INC | COM | 156944100 |  | 1217574 | 29325 | SH |  | SOLE |  | 29325 | 0 | 0 |
| CIDARA THERAPEUTICS INC | COM NEW | 171757206 |  | 5064566 | 22928 | SH |  | SOLE |  | 22928 | 0 | 0 |
| CIENA CORP | COM NEW | 171779309 |  | 1212616 | 5185 | SH |  | SOLE |  | 5185 | 0 | 0 |
| CLEAN HARBORS INC | COM | 184496107 |  | 1463859 | 6243 | SH |  | SOLE |  | 6243 | 0 | 0 |
| CLEVELAND-CLIFFS INC NEW | COM | 185899101 |  | 1574663 | 118574 | SH |  | SOLE |  | 118574 | 0 | 0 |
| CNX RES CORP | COM | 12653C108 |  | 648034 | 17624 | SH |  | SOLE |  | 17624 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 11958412 | 336667 | SH |  | SOLE |  | 336667 | 0 | 0 |
| COMPANIA DE MINAS BUENAVENTU | SPONSORED ADR | 204448104 |  | 825132 | 29649 | SH |  | SOLE |  | 29649 | 0 | 0 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 |  | 3442637 | 498933 | SH |  | SOLE |  | 498933 | 0 | 0 |
| COMPASS THERAPEUTICS INC | COM | 20454B104 |  | 1318507 | 245532 | SH |  | SOLE |  | 245532 | 0 | 0 |
| CONSTELLATION ENERGY CORP | COM | 21037T109 |  | 1699935 | 4812 | SH |  | SOLE |  | 4812 | 0 | 0 |
| CORE SCIENTIFIC INC NEW | COM | 21874A106 |  | 924735 | 63512 | SH |  | SOLE |  | 63512 | 0 | 0 |
| CORPORACION AMER ARPTS S A | COM | L1995B107 |  | 965770 | 37145 | SH |  | SOLE |  | 37145 | 0 | 0 |
| COUPANG INC | CL A | 22266T109 |  | 584843 | 24792 | SH |  | SOLE |  | 24792 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 7279396 | 114564 | SH |  | SOLE |  | 114564 | 0 | 0 |
| CYTOMX THERAPEUTICS INC | COM | 23284F105 |  | 826189 | 193941 | SH |  | SOLE |  | 193941 | 0 | 0 |
| DBV TECHNOLOGIES S A | SPONSORED ADS | 23306J309 |  | 304362 | 15877 | SH |  | SOLE |  | 15877 | 0 | 0 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 |  | 1998026 | 48484 | SH |  | SOLE |  | 48484 | 0 | 0 |
| DYNE THERAPEUTICS INC | COM | 26818M108 |  | 1166617 | 59643 | SH |  | SOLE |  | 59643 | 0 | 0 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 |  | 4246765 | 171137 | SH |  | SOLE |  | 171137 | 0 | 0 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 |  | 1271055 | 82536 | SH |  | SOLE |  | 82536 | 0 | 0 |
| ENTERGY CORP NEW | COM | 29364G103 |  | 954617 | 10328 | SH |  | SOLE |  | 10328 | 0 | 0 |
| EQT CORP | COM | 26884L109 |  | 1452024 | 27090 | SH |  | SOLE |  | 27090 | 0 | 0 |
| FERGUSON ENTERPRISES INC | COMMON STOCK NEW | 31488V107 |  | 1552399 | 6973 | SH |  | SOLE |  | 6973 | 0 | 0 |
| FLOWSERVE CORP | COM | 34354P105 |  | 1731586 | 24958 | SH |  | SOLE |  | 24958 | 0 | 0 |
| FULL TRUCK ALLIANCE CO LTD | SPONSORED ADS | 35969L108 |  | 939851 | 87591 | SH |  | SOLE |  | 87591 | 0 | 0 |
| GE VERNOVA INC | COM | 36828A101 |  | 1155512 | 1768 | SH |  | SOLE |  | 1768 | 0 | 0 |
| GH RESEARCH PLC | ORDINARY SHARES | G3855L106 |  | 3054655 | 240524 | SH |  | SOLE |  | 240524 | 0 | 0 |
| GITLAB INC | CLASS A COM | 37637K108 |  | 724517 | 19305 | SH |  | SOLE |  | 19305 | 0 | 0 |
| GUARDANT HEALTH INC | COM | 40131M109 |  | 3754462 | 36758 | SH |  | SOLE |  | 36758 | 0 | 0 |
| HDFC BANK LTD | SPONSORED ADS | 40415F101 |  | 808521 | 22127 | SH |  | SOLE |  | 22127 | 0 | 0 |
| HEWLETT PACKARD ENTERPRISE C | COM | 42824C109 |  | 1829867 | 76181 | SH |  | SOLE |  | 76181 | 0 | 0 |
| ICICI BANK LIMITED | ADR | 45104G104 |  | 783263 | 26284 | SH |  | SOLE |  | 26284 | 0 | 0 |
| IMMUNOCORE HLDGS PLC | ADS | 45258D105 |  | 1145361 | 32998 | SH |  | SOLE |  | 32998 | 0 | 0 |
| IMMUNOVANT INC | COM | 45258J102 |  | 5640266 | 221883 | SH |  | SOLE |  | 221883 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 6857176 | 39400 | SH |  | SOLE |  | 39400 | 0 | 0 |
| INTUIT | COM | 461202103 |  | 1200968 | 1813 | SH |  | SOLE |  | 1813 | 0 | 0 |
| INVESCO DB COMMDY INDX TRCK | UNIT | 46138B103 |  | 23639842 | 1057238 | SH |  | SOLE |  | 1057238 | 0 | 0 |
| JANUX THERAPEUTICS INC | COM | 47103J105 |  | 571913 | 41443 | SH |  | SOLE |  | 41443 | 0 | 0 |
| JD.COM INC | SPON ADS CL A | 47215P106 |  | 501189 | 17463 | SH |  | SOLE |  | 17463 | 0 | 0 |
| KANZHUN LIMITED | SPONSORED ADS | 48553T106 |  | 419787 | 20598 | SH |  | SOLE |  | 20598 | 0 | 0 |
| KBR INC | COM | 48242W106 |  | 1206241 | 30006 | SH |  | SOLE |  | 30006 | 0 | 0 |
| KYMERA THERAPEUTICS INC | COM | 501575104 |  | 531831 | 6835 | SH |  | SOLE |  | 6835 | 0 | 0 |
| LB PHARMACEUTICALS INC | COM SHS | 50180M108 |  | 3118782 | 140107 | SH |  | SOLE |  | 140107 | 0 | 0 |
| LIQUIDIA CORPORATION | COM NEW | 53635D202 |  | 5380543 | 156003 | SH |  | SOLE |  | 156003 | 0 | 0 |
| LUMENTUM HLDGS INC | COM | 55024U109 |  | 1591203 | 4317 | SH |  | SOLE |  | 4317 | 0 | 0 |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 |  | 1653263 | 2839 | SH |  | SOLE |  | 2839 | 0 | 0 |
| MASTEC INC | COM | 576323109 |  | 1092719 | 5027 | SH |  | SOLE |  | 5027 | 0 | 0 |
| MASTERCARD INCORPORATED | CL A | 57636Q104 |  | 1589330 | 2784 | SH |  | SOLE |  | 2784 | 0 | 0 |
| MAZE THERAPEUTICS INC | COM | 578784100 |  | 7057724 | 170353 | SH |  | SOLE |  | 170353 | 0 | 0 |
| MERCADOLIBRE INC | COM | 58733R102 |  | 936631 | 465 | SH |  | SOLE |  | 465 | 0 | 0 |
| META PLATFORMS INC | CL A | 30303M102 |  | 1691151 | 2562 | SH |  | SOLE |  | 2562 | 0 | 0 |
| MICROSOFT CORP | COM | 594918104 |  | 3161424 | 6537 | SH |  | SOLE |  | 6537 | 0 | 0 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 |  | 4519702 | 124544 | SH |  | SOLE |  | 124544 | 0 | 0 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 |  | 496748 | 11749 | SH |  | SOLE |  | 11749 | 0 | 0 |
| NEW ORIENTAL ED  TECHNOLOGY | SPON ADR | 647581206 |  | 705320 | 12817 | SH |  | SOLE |  | 12817 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 |  | 1248357 | 35586 | SH |  | SOLE |  | 35586 | 0 | 0 |
| NEXTERA ENERGY INC | COM | 65339F101 |  | 1548200 | 19285 | SH |  | SOLE |  | 19285 | 0 | 0 |
| NOKIA CORP | SPONSORED ADR | 654902204 |  | 385120 | 59524 | SH |  | SOLE |  | 59524 | 0 | 0 |
| NU HLDGS LTD | ORD SHS CL A | G6683N103 |  | 1047422 | 62570 | SH |  | SOLE |  | 62570 | 0 | 0 |
| NUVALENT INC | COM | 670703107 |  | 7371939 | 73287 | SH |  | SOLE |  | 73287 | 0 | 0 |
| NVIDIA CORPORATION | COM | 67066G104 |  | 2652030 | 14220 | SH |  | SOLE |  | 14220 | 0 | 0 |
| OCULAR THERAPEUTIX INC | COM | 67576A100 |  | 4176974 | 344067 | SH |  | SOLE |  | 344067 | 0 | 0 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 |  | 6037225 | 241489 | SH |  | SOLE |  | 241489 | 0 | 0 |
| ORTHOFIX MED INC | COM | 68752M108 |  | 1289343 | 85049 | SH |  | SOLE |  | 85049 | 0 | 0 |
| PALISADE BIO INC | COM | 696389402 |  | 3055073 | 1300031 | SH |  | SOLE |  | 1300031 | 0 | 0 |
| PENNYMAC FINL SVCS INC NEW | COM | 70932M107 |  | 1029143 | 7806 | SH |  | SOLE |  | 7806 | 0 | 0 |
| PETROLEO BRASILEIRO SA PETRO | SP ADR NON VTG | 71654V101 |  | 622104 | 55200 | SH |  | SOLE |  | 55200 | 0 | 0 |
| PHARVARIS N V | COM | N69605108 |  | 4505768 | 162370 | SH |  | SOLE |  | 162370 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 7616376 | 25841 | SH |  | SOLE |  | 25841 | 0 | 0 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 |  | 6423420 | 73545 | SH |  | SOLE |  | 73545 | 0 | 0 |
| PTC INC | COM | 69370C100 |  | 1110415 | 6374 | SH |  | SOLE |  | 6374 | 0 | 0 |
| PURE STORAGE INC | CL A | 74624M102 |  | 1166577 | 17409 | SH |  | SOLE |  | 17409 | 0 | 0 |
| QXO INC | COM NEW | 82846H405 |  | 1132709 | 58720 | SH |  | SOLE |  | 58720 | 0 | 0 |
| RBC BEARINGS INC | COM | 75524B104 |  | 1212106 | 2703 | SH |  | SOLE |  | 2703 | 0 | 0 |
| REDDIT INC | CL A | 75734B100 |  | 1218311 | 5300 | SH |  | SOLE |  | 5300 | 0 | 0 |
| RELAY THERAPEUTICS INC | COM | 75943R102 |  | 4611368 | 545079 | SH |  | SOLE |  | 545079 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 |  | 9577116 | 120240 | SH |  | SOLE |  | 120240 | 0 | 0 |
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 |  | 4588483 | 42867 | SH |  | SOLE |  | 42867 | 0 | 0 |
| ROBLOX CORP | CL A | 771049103 |  | 683164 | 8431 | SH |  | SOLE |  | 8431 | 0 | 0 |
| ROCKET COS INC | COM CL A | 77311W101 |  | 1886245 | 97430 | SH |  | SOLE |  | 97430 | 0 | 0 |
| RXO INC | COMMON STOCK | 74982T103 |  | 1149456 | 90938 | SH |  | SOLE |  | 90938 | 0 | 0 |
| SALESFORCE INC | COM | 79466L302 |  | 2281670 | 8613 | SH |  | SOLE |  | 8613 | 0 | 0 |
| SANDISK CORP | COM | 80004C200 |  | 1039250 | 4378 | SH |  | SOLE |  | 4378 | 0 | 0 |
| SCHWAB CHARLES CORP | COM | 808513105 |  | 1059146 | 10601 | SH |  | SOLE |  | 10601 | 0 | 0 |
| SEA LTD | SPONSORD ADS | 81141R100 |  | 950396 | 7450 | SH |  | SOLE |  | 7450 | 0 | 0 |
| SEPTERNA INC | COM | 81734D104 |  | 2193654 | 78682 | SH |  | SOLE |  | 78682 | 0 | 0 |
| SHIFT4 PMTS INC | CL A | 82452J109 |  | 817477 | 12982 | SH |  | SOLE |  | 12982 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 |  | 6253695 | 135069 | SH |  | SOLE |  | 135069 | 0 | 0 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 |  | 6165629 | 188206 | SH |  | SOLE |  | 188206 | 0 | 0 |
| STOKE THERAPEUTICS INC | COM | 86150R107 |  | 3667208 | 115539 | SH |  | SOLE |  | 115539 | 0 | 0 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 |  | 13423219 | 193001 | SH |  | SOLE |  | 193001 | 0 | 0 |
| TALEN ENERGY CORP | COM | 87422Q109 |  | 1307442 | 3488 | SH |  | SOLE |  | 3488 | 0 | 0 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 |  | 4385821 | 53564 | SH |  | SOLE |  | 53564 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 7088665 | 175462 | SH |  | SOLE |  | 175462 | 0 | 0 |
| THERMO FISHER SCIENTIFIC INC | COM | 883556102 |  | 1314772 | 2269 | SH |  | SOLE |  | 2269 | 0 | 0 |
| TRANSDIGM GROUP INC | COM | 893641100 |  | 2892424 | 2175 | SH |  | SOLE |  | 2175 | 0 | 0 |
| TREVI THERAPEUTICS INC | COM | 89532M101 |  | 1329110 | 106159 | SH |  | SOLE |  | 106159 | 0 | 0 |
| TRIP COM GROUP LTD | ADS | 89677Q107 |  | 765554 | 10646 | SH |  | SOLE |  | 10646 | 0 | 0 |
| TYRA BIOSCIENCES INC | COM | 90240B106 |  | 922411 | 35086 | SH |  | SOLE |  | 35086 | 0 | 0 |
| UNIFIRST CORP MASS | COM | 904708104 |  | 1490538 | 7727 | SH |  | SOLE |  | 7727 | 0 | 0 |
| UNION PAC CORP | COM | 907818108 |  | 1863977 | 8058 | SH |  | SOLE |  | 8058 | 0 | 0 |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 |  | 1135293 | 2330 | SH |  | SOLE |  | 2330 | 0 | 0 |
| UNITY SOFTWARE INC | COM | 91332U101 |  | 1266045 | 28663 | SH |  | SOLE |  | 28663 | 0 | 0 |
| UROGEN PHARMA LTD | COM | M96088105 |  | 655877 | 28005 | SH |  | SOLE |  | 28005 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 5262221 | 114049 | SH |  | SOLE |  | 114049 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 |  | 11591329 | 372472 | SH |  | SOLE |  | 372472 | 0 | 0 |
| VISA INC | COM CL A | 92826C839 |  | 2206316 | 6291 | SH |  | SOLE |  | 6291 | 0 | 0 |
| VISTRA CORP | COM | 92840M102 |  | 915225 | 5673 | SH |  | SOLE |  | 5673 | 0 | 0 |
| WORKDAY INC | CL A | 98138H101 |  | 1393063 | 6486 | SH |  | SOLE |  | 6486 | 0 | 0 |
| XCEL ENERGY INC | COM | 98389B100 |  | 595164 | 8058 | SH |  | SOLE |  | 8058 | 0 | 0 |
| XOMA ROYALTY CORPORATION | COM NEW | 98419J206 |  | 3002463 | 112917 | SH |  | SOLE |  | 112917 | 0 | 0 |
| XPO INC | COM | 983793100 |  | 1729183 | 12723 | SH |  | SOLE |  | 12723 | 0 | 0 |

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