# EDGAR Filing Document

**Accession Number:** 0001552740
**File Stem:** 0001145549-23-007889
**Filing Date:** 2023-2
**Character Count:** 29415
**Document Hash:** aebbd29ea34a9cbb62597fb2409841e2
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001145549-23-007889.hdr.sgml**: 20230222

**ACCESSION NUMBER**: 0001145549-23-007889

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20221230

**FILED AS OF DATE**: 20230222

**DATE AS OF CHANGE**: 20230222

**PERIOD START**: 20230331

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIRST TRUST EXCHANGE-TRADED FUND VI
- **CENTRAL INDEX KEY:** 0001552740
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** MA

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-22717
- **FILM NUMBER:** 23651894

**BUSINESS ADDRESS:**
- **STREET 1:** 120 EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187
- **BUSINESS PHONE:** 630-765-8000

**MAIL ADDRESS:**
- **STREET 1:** 120 EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187

## Series and Classes Contracts Data

### First Trust Indxx Medical Devices ETF (Series ID: S000071976)

| Class ID   | Class Name                            | Ticker Symbol   |
|:---|:---|:---|
| C000227613 | First Trust Indxx Medical Devices ETF | MDEV            |

## Nport-Ex

#### First Trust Indxx Medical Devices ETF (MDEV)<br>

#### Portfolio of Investments

#### December 31, 2022 (Unaudited)

---

| | | |
|:---|:---|:---|
| **Shares** | **Description** | **Value** |
| **COMMON STOCKS – 99.7%** | **COMMON STOCKS – 99.7%** | **COMMON STOCKS – 99.7%** |
|  | **Biotechnology – 2.9%** |  |
| 1104 | Exact Sciences Corp. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;$54659 |
|  | **Health Care Equipment &<br> Supplies – 74.6%** |  |
| &nbsp;&nbsp;332 | Abbott Laboratories | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;36450 |
| &nbsp;&nbsp;574 | Alcon, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39221 |
| &nbsp;&nbsp;166 | Align Technology, Inc. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;35009 |
| &nbsp;&nbsp;615 | Baxter International, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;31347 |
| &nbsp;&nbsp;149 | Becton Dickinson and Co. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;37891 |
| &nbsp;&nbsp;419 | BioMerieux | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;43919 |
| &nbsp;&nbsp;838 | Boston Scientific Corp. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;38774 |
| &nbsp;&nbsp;296 | Carl Zeiss Meditec AG | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;37357 |
| &nbsp;&nbsp;274 | Cochlear Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;38079 |
| &nbsp;&nbsp;328 | Coloplast A.S., Class B | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;38339 |
| &nbsp;&nbsp;135 | Cooper (The) Cos., Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;44640 |
| 1263 | Demant A.S. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;35008 |
| 1177 | DENTSPLY SIRONA, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;37476 |
| &nbsp;&nbsp;344 | DexCom, Inc. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;38955 |
| &nbsp;&nbsp;407 | Edwards Lifesciences Corp. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;30366 |
| 3209 | Fisher & Paykel Healthcare Corp., Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;46045 |
| &nbsp;&nbsp;551 | Globus Medical, Inc., Class A (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;40923 |
| &nbsp;&nbsp;536 | Hologic, Inc. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;40098 |
| &nbsp;&nbsp;294 | Hoya Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;28461 |
| &nbsp;&nbsp;152 | Insulet Corp. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;44747 |
| &nbsp;&nbsp;183 | Intuitive Surgical, Inc. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;48559 |
| 2549 | Koninklijke Philips N.V. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;38211 |
| &nbsp;&nbsp;253 | Masimo Corp. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;37431 |
| &nbsp;&nbsp;411 | Medtronic PLC | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;31943 |
| &nbsp;&nbsp;458 | Novocure Ltd. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;33594 |
| 1640 | Olympus Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;29391 |
| &nbsp;&nbsp;158 | ResMed, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;32885 |
| &nbsp;&nbsp;788 | Siemens Healthineers AG (b) (c) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39417 |
| 2981 | Smith & Nephew PLC | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39985 |
| &nbsp;&nbsp;151 | Sonova Holding AG | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;35813 |
| &nbsp;&nbsp;202 | STERIS PLC | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;37307 |
| &nbsp;&nbsp;357 | Straumann Holding AG | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;40771 |
| &nbsp;&nbsp;160 | Stryker Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39118 |
| &nbsp;&nbsp;678 | Sysmex Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;41319 |
| &nbsp;&nbsp;171 | Teleflex, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;42687 |
| 1130 | Terumo Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;32254 |
| &nbsp;&nbsp;313 | Zimmer Biomet Holdings, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39908 |
|  |  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1403698 |
|  | **Health Care Providers &<br> Services – 2.2%** |  |
| 1391 | Amplifon S.p.A. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;41424 |
|  | **Life Sciences Tools &<br> Services – 20.0%** |  |
| &nbsp;&nbsp;267 | Agilent Technologies, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39957 |
| &nbsp;&nbsp;&nbsp;&nbsp;85 | Bio-Rad Laboratories, Inc., Class A (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;35742 |
| &nbsp;&nbsp;132 | Danaher Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;35035 |
| &nbsp;&nbsp;&nbsp;&nbsp;30 | Mettler-Toledo International, Inc. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;43364 |

---

---

| | | |
|:---|:---|:---|
| **Shares** | **Description** | **Value** |
|  | **Life Sciences Tools &<br> Services (Continued)** |  |
| &nbsp;&nbsp;279 | PerkinElmer, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;$39121 |
| &nbsp;&nbsp;102 | Sartorius Stedim Biotech | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;33029 |
| &nbsp;&nbsp;&nbsp;&nbsp;67 | Thermo Fisher Scientific, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;36896 |
| &nbsp;&nbsp;123 | Waters Corp. (a) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;42137 |
| &nbsp;&nbsp;135 | West Pharmaceutical Services, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;31772 |
| 3752 | WuXi AppTec Co., Ltd.,<br> Class H (b) (c) | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39633 |
|  |  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;376686 |
|  | **Total Investments – 99.7%** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1876467 |
|  | (Cost $2,636,776) |  |
|  | **Net Other Assets and Liabilities – 0.3%** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5542 |
|  | **Net Assets – 100.0%** | &nbsp;&nbsp;&nbsp;&nbsp;$1882009 |

---

(a) Non-income producing security.

(b) This security may be resold to qualified foreign investors and foreign institutional buyers under Regulation S of the Securities Act of 1933, as amended (the "1933 Act").

(c) This security is exempt from registration upon resale under Rule 144A of the 1933 Act and may be resold in transactions exempt from registration, normally to
qualified institutional buyers. This security is not restricted on the foreign exchange where it trades freely without any additional registration. As such, it does not require the additional disclosure required of
restricted securities.

------

#### Valuation Inputs
The Fund is subject to fair value accounting standards that define fair value, establish the framework for measuring fair value and provide a three-level hierarchy for fair valuation based upon the inputs to the valuation as of the measurement date. The three levels of the fair value hierarchy are as follows:

• Level 1 – Level 1 inputs are quoted prices in active markets for identical investments.

• Level 2 – Level 2 inputs are observable inputs, either directly or indirectly. (Quoted prices for similar investments, valuations based on interest rates and yield curves, or valuations derived
from observable market data.)

• Level 3 – Level 3 inputs are unobservable inputs that may reflect the reporting entity's own assumptions about the assumptions that market participants would use in
pricing the investment.

The inputs or methodologies used for valuing investments are not necessarily an indication of the risk associated with investing in those investments.

------

#### First Trust Indxx Medical Devices ETF (MDEV)<br>

#### Portfolio of Investments (Continued)

#### December 31, 2022 (Unaudited)
A summary of the inputs used to value the Fund's investments as of December 31, 2022 is as follows:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Total<br> Value at<br> 12/31/2022** | &nbsp;&nbsp;**Level 1<br> Quoted<br> Prices** | **Level 2<br> Significant<br> Observable<br> Inputs** | **Level 3<br> Significant<br> Unobservable<br> Inputs** |
| Common Stocks\* | $1876467 | &nbsp;&nbsp;$1876467 | $— | $— |

---

\* See Portfolio of Investments for industry breakout.

------

#### Additional Information

#### First Trust Indxx Medical Devices ETF (MDEV)

#### December 31, 2022 (Unaudited)

#### Licensing Information
Indxx and Indxx Global Medical Equipment Index ("Index") are trademarks of Indxx, Inc. ("Indxx") and have been licensed for use for certain purposes by First Trust. The Fund is not sponsored, endorsed, sold or promoted by Indxx and Indxx makes no representation regarding the advisability of trading in such product. The Index is determined, composed and calculated by Indxx without regard to First Trust or the Fund.

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** First Trust Exchange-Traded Fund VI

- **b. Investment Company Act file number:** 811-22717

- **c. CIK number of Registrant:** 0001552740

- **d. LEI of Registrant:** 549300ZLB3EUU3H8NE60

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 120 East Liberty Drive, Suite 400

  - **City:** Wheaton

  - **State:** IL

  - **Foreign country:** US

  - **Zip / Postal Code:** 60187

  - **Telephone number:** 630-765-8000

**Item A.2. Information about the Series.**

- **a. Name of Series:** First Trust Indxx Medical Devices ETF

- **b. EDGAR series identifier (if any):** S000071976

- **c. LEI of Series:** 549300I7ZP4IRE34QB73

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2023-03-31

- **b. Date as of which information is reported:** 2022-12-30

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $1883129.15

**Total Liabilities:** $1119.83

**Net Assets:** $1882009.32

**Cash Not Reported:** $4763.88

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000227613 | 5.34%                | 10.55%               | -0.79%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-56935.27               | $144865.72                                 |
| Month 2  | $0.00                    | $182179.23                                 |
| Month 3  | $4919.48                 | $-21054.20                                 |

### Schedule of Portfolio Investments

| Name                                      | Title                          | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Abbott Laboratories                       | ABBOTT LABORATORIES            | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |       332 | NS      | $36450.28     | 1.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc.                 | AGILENT TECHNOLOGIES INC       | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |       267 | NS      | $39956.55     | 2.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc.                     | ALIGN TECHNOLOGY INC           | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |       166 | NS      | $35009.40     | 1.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Baxter International, Inc.                | BAXTER INTERNATIONAL INC       | CUSIP: 071813109<br>LEI: J5OIVXX3P24RJRW5CK77 | Long             | EC               | CORP              | US        |       615 | NS      | $31346.55     | 1.67%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton, Dickinson and Company             | BECTON DICKINSON AND CO        | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |       149 | NS      | $37890.70     | 2.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Rad Laboratories, Inc.                | BIO-RAD LABORATORIES-A         | CUSIP: 090572207<br>LEI: 549300ZC1GPV35XYDK53 | Long             | EC               | CORP              | US        |        85 | NS      | $35741.65     | 1.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Smith & Nephew PLC                        | SMITH & NEPHEW PLC /GBP/       | CUSIP: G82343164<br>LEI: 213800ZTMDN8S67S1H61 | Long             | EC               | CORP              | GB        |      2981 | NS      | $39985.05     | 2.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Boston Scientific Corporation             | BOSTON SCIENTIFIC CORP         | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |       838 | NS      | $38774.26     | 2.06%             |  |  |  | No            |                  1 | On Loan: No      |
| The Cooper Companies, Inc.                | COOPER COS INC/THE             | CUSIP: 216648402<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |       135 | NS      | $44640.45     | 2.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Danaher Corporation                       | DANAHER CORP                   | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |       132 | NS      | $35035.44     | 1.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Dentsply Sirona Inc                       | DENTSPLY SIRONA INC            | CUSIP: 24906P109<br>LEI: 9NHEHR1SOZCYXDO8HO28 | Long             | EC               | CORP              | US        |      1177 | NS      | $37475.68     | 1.99%             |  |  |  | No            |                  1 | On Loan: No      |
| DexCom Inc                                | DEXCOM INC                     | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |       344 | NS      | $38954.56     | 2.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Edwards Lifesciences Corporation          | EDWARDS LIFESCIENCES CORP      | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |       407 | NS      | $30366.27     | 1.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corporation                | EXACT SCIENCES CORP            | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |      1104 | NS      | $54659.04     | 2.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Med Inc                            | GLOBUS MEDICAL INC-A           | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |       551 | NS      | $40922.77     | 2.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                               | HOLOGIC INC                    | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |       536 | NS      | $40098.16     | 2.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corporation                       | INSULET CORP                   | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |       152 | NS      | $44747.28     | 2.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc.                   | INTUITIVE SURGICAL INC         | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |       183 | NS      | $48559.05     | 2.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Masimo Corporation                        | MASIMO CORP                    | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |       253 | NS      | $37431.35     | 1.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Carl Zeiss Meditec AG                     | CARL ZEISS MEDITEC AG -  /EUR/ | CUSIP: D14895102<br>LEI: 529900GRL4MZ8NMOOK95 | Long             | EC               | CORP              | DE        |       296 | NS      | $37356.99     | 1.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Mettler-Toledo International Inc          | METTLER-TOLEDO INTERNATIONAL   | CUSIP: 592688105<br>LEI: 5493000BD5GJNUDIUG10 | Long             | EC               | CORP              | US        |        30 | NS      | $43363.50     | 2.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Royal Philips NV                          | KONINKLIJKE PHILIPS NV /EUR/   | CUSIP: N6817P109<br>LEI: H1FJE8H61JGM1JSGM897 | Long             | EC               | CORP              | NL        |      2549 | NS      | $38211.00     | 2.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Cochlear Ltd                              | COCHLEAR LTD /AUD/             | CUSIP: Q25953102<br>LEI: 5493001OLLWY8KV5UC08 | Long             | EC               | CORP              | AU        |       274 | NS      | $38079.18     | 2.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Fisher & Paykel Healthcare Corp Ltd.      | FISHER & PAYKEL HEALTHCA /NZD/ | CUSIP: Q38992105<br>LEI: N/A                  | Long             | EC               | CORP              | NZ        |      3209 | NS      | $46045.10     | 2.45%             |  |  |  | No            |                  1 | On Loan: No      |
| HOYA Corp.                                | HOYA CORP /JPY/                | CUSIP: J22848105<br>LEI: 353800X4VR3BHEUCJB42 | Long             | EC               | CORP              | JP        |       294 | NS      | $28461.37     | 1.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Olympus Corp.                             | OLYMPUS CORP /JPY/             | CUSIP: J61240107<br>LEI: 5299000Y52IFDI1I2A21 | Long             | EC               | CORP              | JP        |      1640 | NS      | $29391.04     | 1.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Sysmex Corp                               | SYSMEX CORP /JPY/              | CUSIP: J7864H102<br>LEI: 5299001ZO4CKWACMZI55 | Long             | EC               | CORP              | JP        |       678 | NS      | $41318.53     | 2.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Terumo Corp                               | TERUMO CORP /JPY/              | CUSIP: J83173104<br>LEI: 353800JX1R4582QVK932 | Long             | EC               | CORP              | JP        |      1130 | NS      | $32253.73     | 1.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Perkinelmer, Inc.                         | PERKINELMER INC                | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |       279 | NS      | $39121.38     | 2.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Sonova Holding AG                         | SONOVA HOLDING AG /CHF/        | CUSIP: H62042124<br>LEI: 5299004A0QNX7FBNHS61 | Long             | EC               | CORP              | CH        |       151 | NS      | $35812.79     | 1.90%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc.                               | RESMED INC                     | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |       158 | NS      | $32884.54     | 1.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Stryker Corporation                       | STRYKER CORP                   | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |       160 | NS      | $39118.40     | 2.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Teleflex Incorporated                     | TELEFLEX INC                   | CUSIP: 879369106<br>LEI: UUL85LWXB4NGSWWXIQ25 | Long             | EC               | CORP              | US        |       171 | NS      | $42686.73     | 2.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc              | THERMO FISHER SCIENTIFIC INC   | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |        67 | NS      | $36896.23     | 1.96%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corporation                        | WATERS CORP                    | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |       123 | NS      | $42137.34     | 2.24%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Incorporated | WEST PHARMACEUTICAL SERVICES   | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |       135 | NS      | $31772.25     | 1.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Zimmer Biomet Holdings Inc                | ZIMMER BIOMET HOLDINGS INC     | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |       313 | NS      | $39907.50     | 2.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Amplifon S.p.A.                           | AMPLIFON SPA /EUR/             | CUSIP: T0388E118<br>LEI: ZYXJDNVM2JI3VBM8G556 | Long             | EC               | CORP              | IT        |      1391 | NS      | $41423.87     | 2.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Coloplast AS                              | COLOPLAST-B /DKK/              | CUSIP: K16018192<br>LEI: 529900NN7SOJ5QG82X67 | Long             | EC               | CORP              | DK        |       328 | NS      | $38339.38     | 2.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Siemens Healthineers AG                   | SIEMENS HEALTHINEERS AG /EUR/  | CUSIP: D6T479107<br>LEI: 529900QBVWXMWANH7H45 | Long             | EC               | CORP              | DE        |       788 | NS      | $39417.44     | 2.09%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMerieux SA                             | BIOMERIEUX /EUR/               | CUSIP: F1149Y232<br>LEI: 549300AK8Y0LBIQ4T071 | Long             | EC               | CORP              | FR        |       419 | NS      | $43918.94     | 2.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Wuxi Apptec Co Ltd.                       | WUXI APPTEC CO LTD-H /HKD/     | CUSIP: Y971B1118<br>LEI: 254900OEPQLZSPLN9175 | Long             | EC               | CORP              | CN        |      3752 | NS      | $39632.87     | 2.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Alcon AG                                  | ALCON INC /CHF/                | CUSIP: H01301128<br>LEI: 549300LDT5AP8S0NBM78 | Long             | EC               | CORP              | CH        |       574 | NS      | $39220.59     | 2.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Straumann Holding AG                      | STRAUMANN HOLDING AG-REG /CHF/ | CUSIP: H8300N127<br>LEI: 50670046ML5FVIM60Z37 | Long             | EC               | CORP              | CH        |       357 | NS      | $40771.32     | 2.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Medtronic PLC                             | MEDTRONIC PLC                  | CUSIP: G5960L103<br>LEI: 549300GX3ZBSQWUXY261 | Long             | EC               | CORP              | IE        |       411 | NS      | $31942.92     | 1.70%             |  |  |  | No            |                  1 | On Loan: No      |
| Novocure Ltd                              | NOVOCURE LTD                   | CUSIP: G6674U108<br>LEI: 213800YPP55UMHWA4826 | Long             | EC               | CORP              | JE        |       458 | NS      | $33594.30     | 1.79%             |  |  |  | No            |                  1 | On Loan: No      |
| Sartorius Stedim Biotech SA               | SARTORIUS STEDIM BIOTECH /EUR/ | CUSIP: F8005V210<br>LEI: 52990006IVXY7GCSSR39 | Long             | EC               | CORP              | FR        |       102 | NS      | $33028.73     | 1.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Demant A/S                                | DEMANT A/S /DKK/               | CUSIP: K3008M105<br>LEI: 213800RM6L9LN78BVA56 | Long             | EC               | CORP              | DK        |      1263 | NS      | $35007.58     | 1.86%             |  |  |  | No            |                  1 | On Loan: No      |
| STERIS PLC                                | STERIS PLC                     | CUSIP: G8473T100<br>LEI: N/A                  | Long             | EC               | CORP              | IE        |       202 | NS      | $37307.38     | 1.98%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2023-01-30

**Name of Applicant:** First Trust Exchange-Traded Fund VI

**Signature:** Donald P. Swade

**Name of Signer:** First Trust Exchange-Traded Fund VI

**Title:** Treasurer, Chief Financial Officer and Chief Accounting Officer