# EDGAR Filing Document

**Accession Number:** 0001961149
**File Stem:** 0001209191-23-002628
**Filing Date:** 2023-1
**Character Count:** 8721
**Document Hash:** 340fcb94bb2196b070034ba7389c2e9f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001209191-23-002628.hdr.sgml**: 20230109

**ACCESSION NUMBER**: 0001209191-23-002628

**CONFORMED SUBMISSION TYPE**: 3

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20230101

**FILED AS OF DATE**: 20230109

**DATE AS OF CHANGE**: 20230109

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** WuXi PharmaTech Healthcare Fund I L.P.
- **CENTRAL INDEX KEY:** 0001678057
- **STATE OF INCORPORATION:** F4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-40505
- **FILM NUMBER:** 23519273

**BUSINESS ADDRESS:**
- **STREET 1:** BUILDING NO. 1, 288 FUTE ZHONG ROAD
- **STREET 2:** WAIGAOQIAO FREE TRADE ZONE
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200131
- **BUSINESS PHONE:** 86-21-50462227

**MAIL ADDRESS:**
- **STREET 1:** BUILDING NO. 1, 288 FUTE ZHONG ROAD
- **STREET 2:** WAIGAOQIAO FREE TRADE ZONE
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200131

**FORMER NAME:**
- **FORMER CONFORMED NAME:** WuXi PharmTech Healthcare Fund I L.P.
- **DATE OF NAME CHANGE:** 20160623
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** WuXi AppTec (Hong Kong) Holding Ltd
- **CENTRAL INDEX KEY:** 0001961149

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-40505
- **FILM NUMBER:** 23519272

**BUSINESS ADDRESS:**
- **STREET 1:** 288 FUTE ZHONG ROAD
- **STREET 2:** PUDONG NEW AREA
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200131
- **BUSINESS PHONE:** 862138707581

**MAIL ADDRESS:**
- **STREET 1:** 288 FUTE ZHONG ROAD
- **STREET 2:** PUDONG NEW AREA
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200131
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** WuXi AppTec Co., Ltd.
- **CENTRAL INDEX KEY:** 0001832424
- **STATE OF INCORPORATION:** F4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-40505
- **FILM NUMBER:** 23519274

**BUSINESS ADDRESS:**
- **STREET 1:** 228 FUTE ZHONG ROAD
- **STREET 2:** WAIGAOQIAO FREE TRADE ZONE
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200131
- **BUSINESS PHONE:** 86-21-5046-1000

**MAIL ADDRESS:**
- **STREET 1:** 228 FUTE ZHONG ROAD
- **STREET 2:** WAIGAOQIAO FREE TRADE ZONE
- **CITY:** SHANGHAI
- **STATE:** F4
- **ZIP:** 200131
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Ambrx Biopharma Inc.
- **CENTRAL INDEX KEY:** 0001836056
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 571147346
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 10975 NORTH TORREY PINES ROAD
- **CITY:** LA JOLLA
- **STATE:** CA
- **ZIP:** 92037
- **BUSINESS PHONE:** (858) 729-3339

**MAIL ADDRESS:**
- **STREET 1:** 10975 NORTH TORREY PINES ROAD
- **CITY:** LA JOLLA
- **STATE:** CA
- **ZIP:** 92037

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 3

### INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>WuXi AppTec Co., Ltd.<br><sub>(Last) (First) (Middle)</sub><br>288 FUTE ZHONG ROAD<br>PUDONG NEW AREA<br><sub>(Street)</sub><br>SHANGHAI, F4 200131<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>Ambrx Biopharma Inc. [ AMAM ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2023-01-01 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>WuXi PharmaTech Healthcare Fund I L.P.<br><sub>(Last) (First) (Middle)</sub><br>288 FUTE ZHONG ROAD<br>PUDONG NEW AREA<br><sub>(Street)</sub><br>SHANGHAI, F4 200131<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>Ambrx Biopharma Inc. [ AMAM ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2023-01-01 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>WuXi AppTec (Hong Kong) Holding Ltd<br><sub>(Last) (First) (Middle)</sub><br>288 FUTE ZHONG ROAD<br>PUDONG NEW AREA<br><sub>(Street)</sub><br>SHANGHAI, F4 200131<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>Ambrx Biopharma Inc. [ AMAM ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2023-01-01 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities Beneficially Owned

---

|  |  |  |  |
| --- | --- | --- | --- |
| 1. Title of Security | 2. Amount of Securities Beneficially Owned | 3. Ownership Form | 4. Nature of Indirect Beneficial Ownership |
| Ordinary Shares<sup>(1)</sup> | 21270767 | I | Held by WuXi PharmaTech Healthcare Fund I, L.P.<sup>(2)</sup> |
| Ordinary Shares<sup>(1)</sup> | 7996920 | I | Held by WuXi AppTec (Hong Kong) Holding Limited<sup>(3)</sup> |

---

## Table II - Derivative Securities Beneficially Owned

---

|  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Date Exercisable and Expiration Date (Month/Day/Year) | 2. Date Exercisable and Expiration Date (Month/Day/Year) | 3. Title and Amount of Underlying Securities | 3. Title and Amount of Underlying Securities | 4. Conversion or Exercise Price | 5. Ownership Form | 6. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 4. Conversion or Exercise Price | 5. Ownership Form | 6. Nature of Indirect Beneficial Ownership |
|  |  |  |  |  |  |  |  |

---

### Footnotes:

(1) The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents seven Ordinary Shares of the Issuer.

(2) Shares are directly held by WuXi PharmaTech Healthcare Fund I, L.P. ("PharmaTech"). PharmaTech is an indirect, wholly owned subsidiary of WuXi AppTec Co., Ltd. ("AppTec Co"), which is the ultimate beneficial owner of PharmaTech and shares voting and investment authority over these shares.

(3) Shares are directly held by WuXi AppTec (Hong Kong) Holding Limited ("AppTec HK"). AppTec HK is an indirect, wholly owned subsidiary of AppTec Co, which is the ultimate beneficial owner of AppTec HK and shares voting and investment authority over these shares.

**Signature:** WuXi AppTec Co., Ltd., By: /s/ Edward Hu, Director  
**Date:** 2023-01-06

**Signature:** WuXi PharmaTech Healthcare Fund I, L.P., By: /s/ Edward Hu, Director  
**Date:** 2023-01-06

**Signature:** WuXi AppTec (Hong Kong) Holding Limited, By: /s/ Edward Hu, Director  
**Date:** 2023-01-06

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**