# EDGAR Filing Document

**Accession Number:** 0002010788
**File Stem:** 0001641172-25-023184
**Filing Date:** 2025-8
**Character Count:** 106990
**Document Hash:** f784b55d1b5e6681b5ec7673f58c4cfc
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001641172-25-023184.hdr.sgml**: 20250812

**ACCESSION NUMBER**: 0001641172-25-023184

**CONFORMED SUBMISSION TYPE**: 10-Q

**PUBLIC DOCUMENT COUNT**: 59

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250812

**DATE AS OF CHANGE**: 20250812

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** EXOZYMES INC.
- **CENTRAL INDEX KEY:** 0002010788
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 834550057
- **STATE OF INCORPORATION:** NV
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 10-Q
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-42204
- **FILM NUMBER:** 251206808

**BUSINESS ADDRESS:**
- **STREET 1:** 750 ROYAL OAKS DR
- **CITY:** MONROVIA
- **STATE:** CA
- **ZIP:** 91016
- **BUSINESS PHONE:** (626) - 415 - 1488

**MAIL ADDRESS:**
- **STREET 1:** 750 ROYAL OAKS DR
- **CITY:** MONROVIA
- **STATE:** CA
- **ZIP:** 91016

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Invizyne Technologies Inc
- **DATE OF NAME CHANGE:** 20240205

?xml version='1.0' encoding='ASCII'?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 10-Q**

☒ **QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934**

**FOR THE QUARTERLY PERIOD ENDED JUNE 30, 2025**

***OR***

☐ **TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934**

Commission File Number: **001-42204**

**EXOZYMES INC.**

(Exact name of registrant as specified in its charter)

---

| | |
|:---|:---|
| **Nevada** | **83-4550057** |
| (State or other jurisdiction of<br> incorporation or organization) | (I.R.S. Employer<br> Identification No.) |
| **750 Royal Oaks Drive, Suite 106**<br> **Monrovia, CA 91016** | **91016** |
| (Address of principal executive offices) | (Zip code) |

---

**(626) 415-1488**

(Registrant's telephone number, including area code)

Securities registered pursuant to Section 12(b) of the Exchange Act:

None

---

| | | |
|:---|:---|:---|
| **Title of each class** | **Trading Symbol(s)** | **Name of each exchange on which registered** |
| Common Stock, $.000001 | EXOZ | Nasdaq Capital Markets |

---

Securities registered pursuant to Section 12(g) of the Act:

None

Indicate by check mark whether the issuer (1) has filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the last 90 days. **YES ☒ NO ☐**

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). **YES ☒ NO ☐**

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "non-accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

---

| | | | |
|:---|:---|:---|:---|
| **Large Accelerated Filer** | **☐** | **Accelerated Filer** | **☐** |
| **Non-accelerated Filer** | **☐** | **Smaller Reporting Company** | **☒** |
|  |  | **Emerging Growth Company** | **☒** |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☒

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). **YES ☐ NO ☒**

As of August 12, 2025, the number of outstanding shares of Common Stock was 8,387,250.

**TABLE OF CONTENTS**

---

| | | |
|:---|:---|:---|
|  |  | **Page**<br> **Number** |
| PART I | [FINANCIAL INFORMATION](#a_001) | 3 |
| [Item 1 - Condensed Unaudited Consolidated Financial Statements](#a_002) | [Item 1 - Condensed Unaudited Consolidated Financial Statements](#a_002) | 3 |
| [Condensed Unaudited Consolidated Balance Sheets –June 30, 2025 and December 31, 2024](#a_003) | [Condensed Unaudited Consolidated Balance Sheets –June 30, 2025 and December 31, 2024](#a_003) | 3 |
| [Condensed Unaudited Consolidated Statements of Operations – Three months and Six months Ended June 30, 2025 and 2024](#a_004) | [Condensed Unaudited Consolidated Statements of Operations – Three months and Six months Ended June 30, 2025 and 2024](#a_004) | 4 |
| [Condensed Unaudited Consolidated Statements of Changes in Equity (Deficit) – Three months and Six months Ended June 30, 2025 and 2024](#a_005) | [Condensed Unaudited Consolidated Statements of Changes in Equity (Deficit) – Three months and Six months Ended June 30, 2025 and 2024](#a_005) | 5 |
| [Condensed Unaudited Consolidated Statements of Cash Flows – Six months Ended June 30, 2025 and 2024](#a_006) | [Condensed Unaudited Consolidated Statements of Cash Flows – Six months Ended June 30, 2025 and 2024](#a_006) | 6 |
| [Notes to Condensed Unaudited Consolidated Financial Statements](#a_007) | [Notes to Condensed Unaudited Consolidated Financial Statements](#a_007) | 7 |
| Item 2 | [Management's Discussion and Analysis of Financial Conditions and Results of Operations](#m_001) | 18 |
| Item 3 | [Quantitative and Qualitative Disclosures About Market Risk](#m_002) | 23 |
| Item 4 | [Controls and Procedures](#m_003) | 23 |
| PART II | [OTHER INFORMATION](#m_004) | 24 |
| Item 1 | [Legal Proceedings](#m_005) | 24 |
| Item 1A | [Risk Factors](#m_006) | 24 |
| Item 2 | [Unregistered Sales of Equity Securities and Use of Proceeds](#m_007) | 24 |
| Item 3 | [Defaults upon Senior Securities](#m_008) | 24 |
| Item 4 | [Mine Safety Disclosures](#m_009) | 24 |
| Item 5 | [Other Information](#m_010) | 24 |
| Item 6 | [Exhibits](#m_011) | 24 |

---

***In this Quarterly Report, unless otherwise indicated, the "Company", "eXoZymes," "we", "us" or "our" refer to eXoZymes Inc. and, where appropriate, together with its wholly owned subsidiary.***

**PART I – FINANCIAL INFORMATION**

**CONDENSED UNAUDITED CONSOLIDATED FINANCIAL STATEMENTS**

**CONDENSED UNAUDITED CONSOLIDATED BALANCE SHEETS**

---

| | | |
|:---|:---|:---|
|  | **June 30, 2025<br> (Unaudited)** | **December 31,<br> 2024** |
| ASSETS |  |  |
| Cash and cash equivalents | $6985858 | $9719310 |
| Grants receivable | 257407 | 737282 |
| Due from affiliates | 346 |  |
| Prepaid expenses and other current assets | 287419 | 363790 |
| Total current assets | 7531030 | 10820382 |
| Property and equipment, net | 821305 | 882445 |
| Operating lease right-of-use asset, net | 1194981 | 1331577 |
| Finance lease right-of-use asset, net | 129593 | - |
| Total assets | $9676909 | $13034404 |
| LIABILITIES AND EQUITY |  |  |
| Accounts payable | $930629 | $924252 |
| Due to affiliates |  | 178966 |
| Operating lease liabilities – current | 243691 | 230027 |
| Finance lease liabilities – current | 42623 | - |
| Total current liabilities | 1216943 | 1333245 |
| Deferred grant reimbursement | 116119 | 123579 |
| Operating lease liabilities - long term | 1021172 | 1156805 |
| Finance lease liabilities - long term | 86970 | - |
| Total liabilities | $2441204 | $2613629 |
| Stockholders' Equity: |  |  |
| Preferred stock, $0.000001 par value, 5,000,000 shares authorized; no shares issued and outstanding on June 30, 2025, and December 31, 2024, respectively. |  |  |
| Common shares, 100,000,000 authorized shares at $0.000001; 8,387,250 and 8,367,810 shares issued and outstanding as of June 30, 2025, and December 31, 2024, respectively | 8 | 8 |
| Additional Paid-in-capital | 23398362 | 22366725 |
| Accumulated (deficit) | (16162665) | (11945958) |
| Total stockholders' equity | 7235705 | 10420775 |
| Total liabilities and equity | $9676909 | $13034404 |

---

See accompanying notes to the condensed unaudited consolidated financial statements.

**CONDENSED UNAUDITED CONSOLIDATED STATEMENTS OF OPERATIONS** 

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months ended June 30,** | **Three Months ended June 30,** | **Six Months ended June 30,** | **Six Months ended June 30,** |
|  | **2025** | **2024** | **2025** | **2024** |
| Total operating income | $- | $- | $- | $- |
| Operating costs: |  |  |  |  |
| General and administrative costs: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Compensation | 1068838 | 731607 | 1682762 | 1121651 |
| &nbsp;&nbsp;&nbsp;Professional fees | 368932 | 289903 | 901167 | 546466 |
| &nbsp;&nbsp;&nbsp;Information technology | 41835 | 9714 | 67152 | 13606 |
| &nbsp;&nbsp;&nbsp;General and administrative-other | 265449 | 59985 | 469689 | 140362 |
| Total general and administrative costs | 1745054 | 1091209 | 3120770 | 1822085 |
| Research and development costs, net | 802991 | 237395 | 1378003 | 514977 |
| Total operating costs | 2548045 | 1328604 | 4498773 | 2337062 |
| Net operating loss | (2548045) | (1328604) | (4498773) | (2337062) |
| Other income/(expense): |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Interest income/ (expense) | 76557 | (29782) | 170864 | (29782) |
| &nbsp;&nbsp;&nbsp;Other income: | 111202 |  | 111202 |  |
| Loss before income taxes | (2360286) | (1358386) | (4216707) | (2366844) |
| Income taxes | - | (2144) | - | (2144) |
| Net loss | $(2360286) | $(1360530) | $(4216707) | $(2368988) |
| Net loss per common share – basic and diluted | $(0.28) | $(0.22) | $(0.50) | $(0.38) |
| Weighted average of common shares outstanding – basic and diluted | 8377265 | 6251111 | 8372564 | 6250557 |

---

See accompanying notes to the condensed unaudited consolidated financial statements.

**CONDENSED UNAUDITED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY** 

**Three and Six Months Ended June 30, 2025**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Common Stock** | **Common Stock** | | | |
|  | **Shares** | **Amount** | **Additional <br> Paid-in**<br>**Capital** | **Accumulated**<br>**Deficit** |<br>**Total** |
| Balance, December 31, 2024 | 8367810 | $8 | $22366725 | $(11945958) | $10420775 |
| Stock options |  |  | 317277 |  | 317277 |
| Net loss | - | - | - | (1856421) | (1856421) |
| Balance, March 31, 2025 | 8367810 | 8 | 22684002 | (13802379) | 8881631 |
| Stock options |  |  | 323479 |  | 323479 |
| Issuance of common stock for compensation | 19440 |  | 243778 |  | 243778 |
| Related party debt forgiveness |  |  | 147103 |  | 147103 |
| Net loss | - | - | - | (2360286) | (2360286) |
| Balance, June 30, 2025 | 8387250 | $&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;8 | $23398362 | $(16162665) | $7235705 |

---

**Three and Six Months Ended June 30, 2024**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Common Stock** | **Common Stock** | | | |
|  | **Shares** | **Amount** | **Additional <br> Paid-in**<br>**Capital** | **Accumulated**<br>**Deficit** |<br>**Total** |
| Balance, December 31, 2023 | 6250002 | $6 | $5700298 | $(6084623) | $(384319) |
| Stock options |  |  | 142810 |  | 142810 |
| Net loss | - | - | - | (1008458) | (1008458) |
| Balance, March 31, 2024 | 6250002 | 6 | 5843108 | (7093081) | (1249967) |
| Stock options |  |  | 348275 |  | 348275 |
| Issuance of common stock due to exercise of options | 2347 |  |  |  |  |
| Net loss | - | - | - | (1360530) | (1360530) |
| Balance, June 30, 2024 | 6252349 | $&nbsp;&nbsp;&nbsp;&nbsp; 6 | $6191383 | $(8453611) | $(2262222) |

---

See accompanying notes to the condensed unaudited consolidated financial statements.

**CONDENSED UNAUDITED CONSOLIDATED STATEMENTS OF CASH FLOWS** 

---

| | | |
|:---|:---|:---|
|  | **Six Months ended June 30,** | **Six Months ended June 30,** |
|  | **2025** | **2024** |
| CASH FLOWS FROM OPERATING ACTIVITIES: |  |  |
| Net loss | $(4216707) | $(2368988) |
| &nbsp;&nbsp;&nbsp;Amortization (accretion) of Deferred Grant Reimbursement | (27158) | (26451) |
| &nbsp;&nbsp;&nbsp;Depreciation of property and equipment | 142759 | 130937 |
| &nbsp;&nbsp;&nbsp;Non-cash lease expense | 14629 | 19223 |
| &nbsp;&nbsp;&nbsp;Stock-based compensation | 884531 | 491085 |
| Changes in operating assets and liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;(Increase) decrease in - |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Grants receivable | 479875 | (264852) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Prepaid expenses and other current assets | 76371 | 52574 |
| &nbsp;&nbsp;&nbsp;Increase (decrease) in - |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accounts payable and Accrued expenses | 6377 | (352091) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Due to related party | (32209) | 104231 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Tax Payable | - | (42267) |
| Net cash used in operating activities | $(2671532) | $(2256599) |
| CASH FLOWS FROM INVESTING ACTIVITIES: |  |  |
| &nbsp;&nbsp;&nbsp;Deferred grant reimbursement | 19699 | 6379 |
| &nbsp;&nbsp;&nbsp;Purchases of property and equipment | (81619) | (186045) |
| Net cash (used in) investing activities | $(61920) | $(179666) |
| CASH FLOWS FROM FINANCING ACTIVITIES: |  |  |
| &nbsp;&nbsp;&nbsp;Related Party Note |  | 2640000 |
| &nbsp;&nbsp;&nbsp;Deferred IPO Cost | - | (112029) |
| &nbsp;&nbsp;&nbsp;Net cash provided by financing activities | $- | $2527971 |
| &nbsp;&nbsp;&nbsp;NET INCREASE (DECREASE) IN CASH, CASH EQUIVALENTS | (2733452) | 91706 |
| &nbsp;&nbsp;&nbsp;CASH AND CASH EQUIVALENTS - BEGINNING OF PERIOD | 9719310 | 66533 |
| &nbsp;&nbsp;&nbsp;CASH AND CASH EQUIVALENTS - END OF PERIOD | $6985858 | $158239 |
| Supplemental disclosures of cash flow information: |  |  |
| &nbsp;&nbsp;&nbsp;Income taxes |  | (42267) |
| &nbsp;&nbsp;&nbsp;Interest expense | $1693 | $- |
| Non-cash investing and financing activities: |  |  |
| &nbsp;&nbsp;&nbsp;Unpaid offering costs included in prepaid expenses |  | (152065) |
| &nbsp;&nbsp;&nbsp;Forgiveness of debt | 147103 |  |
| &nbsp;&nbsp;&nbsp;Conversion of due to affiliate to related party note |  | 200000 |

---

See accompanying notes to condensed unaudited consolidated financial statements.

**EXOZYMES INC.**

**NOTES TO CONDENSED UNAUDITED CONSOLIDATED FINANCIAL STATEMENTS**

**(Unaudited)**

**Six Months Ended June 30, 2025 and 2024**

**1. Organization and Description of Business**

eXoZymes Inc., formerly known as Invizyne Technologies Inc., was formed in Nevada in 2019 and its wholly owned subsidiary eXoZymes (CA) Inc., formerly known as Invizyne Technologies Inc., was formed in California in 2014, together ("eXoZymes") eXoZymes was formed with the vision of taking nature's building blocks to make molecules of interest, effectively simplifying nature. eXoZymes' technology is a differentiated and unique synthetic biology platform which would enable the scalable exploration of large number of molecules and properties found in nature. eXoZymes was a majority owned technology development subsidiary of MDB Capital Holdings, LLC ("MDB") until the November 2024 initial public offering, when the holdings by MDB were diluted to a current 48% minority interest as of June 30, 2025.

On June 1, 2022, the Company signed a joint venture with Neuractas Therapeutics, a preclinical company developing high impact therapeutics, to work with the Company on deuterated cannabinoid molecules, for which the Company has filed a provisional patent application. No business activities have occurred to date. The Company follows Accounting Standards Codification subtopic 323-10, Investments-Equity Methods and Joint Ventures ("ASC 323-10").

On October 3, 2024, our board of directors approved a two-for-one (2:1) stock split of our issued and outstanding Common Stock. No fractional shares were issued because of the stock split; any fractional share resulting from the stock split was rounded up to the next whole share. As a result of the stock split, proportionate adjustments were made to the per share exercise price and/or the number of shares issuable upon the exercise or vesting of all stock options, restricted stock units and warrants issued by us and outstanding immediately prior to the effective time of the stock split, which resulted in a proportionate decrease in the number of shares of our Common Stock reserved for issuance upon exercise or vesting of such stock options, restricted stock units and warrants and a proportionate increase in the exercise price of all such stock options, restricted stock units and warrants. In addition, the number of shares reserved for issuance under our equity compensation plans were decreased proportionately. All share and per share amounts of Common Stock have been retroactively adjusted to reflect the Common Stock split.

On May 5, 2025, the Company established a wholly owned subsidiary NCTx LLC, a Delaware Limited Liability Company. NCTx LLC is a special purpose subsidiary company focused on the development and production of N-trans-caffeoyltyramine - a very rare, plant-derived compound with emerging relevance in the areas of metabolic health, gut integrity, and liver function. The entity has had no business activities to date.

**Going Concern**

These condensed unaudited consolidated financial statements have been prepared on a going concern basis, which implies that the Company will continue to realize its assets and discharge its liabilities in the normal course of business. The Company incurred net losses of $4,216,707 and $2,368,988 during the six months ended June 30, 2025 and 2024, respectively, and used cash for operations of $(2,671,532) and $(2,256,599) for the six months ended June 30, 2025 and 2024, respectively. Although the Company believes it has sufficient working capital for the near term, management believes that there remains substantial doubt about its ability to continue as a going concern due to anticipated funding shortfalls and the Company's pre-revenue status. The Company's ability to meet its long-term liabilities and obligations depends on securing additional financial support, whether through continued shareholder funding, raising equity or debt financing, or ultimately achieving profitable operations. These financial statements do not include any adjustments to the recoverability and classification of recorded asset amounts or the classification of liabilities that may be necessary should the Company be unable to continue as a going concern.

**2. Summary of Significant Accounting Policies**

**Basis of Presentation and Principles of Consolidation**

The accompanying condensed unaudited consolidated financial statements include the accounts of the Company and wholly owned subsidiary. The accompanying condensed unaudited consolidated financial statements and related notes have been prepared in accordance with U.S. generally accepted accounting principles ("U.S. GAAP"). All intercompany accounts and transactions have been eliminated in consolidation.

**Use of Estimates**

The preparation of financial statements in conformity with Generally Accepted Accounting Principles ("GAAP") requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period, as well as the disclosure of contingent assets and liabilities. Some of those judgments can be subjective and complex, and therefore, actual results could differ materially from those estimates under different assumptions or conditions. Management bases its estimates on historical experience and on various assumptions that are believed to be reasonable in relation to the financial statements taken under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Management regularly evaluates the key factors and assumptions used to develop the estimates utilizing currently available information, changes in facts and circumstances, historical experience and reasonable assumptions. After such evaluations, if deemed appropriate, those estimates are adjusted accordingly. Actual results could differ from those estimates. Significant estimates include those related to assumptions used in the calculation of right-of-use asset and lease liabilities, accruals for potential liabilities and stock-based compensation.

***Recent Accounting Pronouncements***

 ****

*ASU 2024-03*

In November 2024, the FASB issued ASU No. 2024-03, *Disaggregation of Income Statement Expenses (DISE)* (**ASU 2024-03**), which requires disclosure of certain categories of expenses such as the purchase of inventory, employee compensation, depreciation, and intangible asset amortization that are components of existing expense captions presented on the face of the income statement. ASU 2024-03 is effective for annual periods beginning after December 15, 2026 and interim periods beginning after December 15, 2027, with early adoption permitted. ASU 2024-03 should be applied prospectively; however, retrospective application is permitted. We are currently evaluating the impact of ASU 2024-03 on our disclosures.

*ASU 2023-07*

In November 2023, the Financial Accounting Standards Board ("FASB") issued Accounting Standards Update ("ASU") 2023-07, Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures ("ASU 2023-07"), which requires all public entities, including public entities with a single reportable segment, to provide in interim and annual periods one or more measures of segment profit or loss used by the chief operating decision maker to allocate resources and assess performance. Additionally, the standard requires disclosures of significant segment expenses and other segment items as well as incremental qualitative disclosures. The Company adopted ASU 2023-07 effective December 31, 2024, on a retrospective basis. The adoption of 2023-07 did not change the way that the Company identifies its reportable segments and, as a result, did not have a material impact on the Company's segment-related disclosures.

*ASU 2023-09*

In December 2023, the FASB issued ASU No. 2023-09, *Improvements to Income Tax Disclosures* (**ASU 2023-09**), which is intended to enhance the transparency of income tax matters within financial statements, providing stakeholders with a clearer understanding of an entity's operations and the associated tax risks. ASU 2023-09 requires public business entities to disclose, on an annual basis, specific categories in the rate reconciliation and provide additional information for reconciling items that meet a specific quantitative threshold. There is a further requirement that public business entities will need to disclose a tabular reconciliation, using both percentages and reporting currency amounts. ASU 2023-09 is effective for fiscal years beginning after December 15, 2024. The adoption of ASU 2023-09 will result in modifications to our income tax disclosures beginning in 2025.

**Emerging Growth Company**

The Company is an "emerging growth company," or "EGC" as defined in Section 2(a) of the Securities Act of 1933, as amended, or the Securities Act, as modified by the Jumpstart Our Business Startups Act of 2012 (the "JOBS Act"), and it may take advantage of certain exemptions from various reporting requirements that are applicable to other public companies that are not emerging growth companies.

Further, Section 102(b)(1) of the JOBS Act exempts emerging growth companies from being required to comply with new or revised financial accounting standards until private companies (that is, those that have not had a Securities Act registration statement declared effective or do not have a class of securities registered under the Securities Exchange Act of 1934, as amended, or the Exchange Act) are required to comply with the new or revised financial accounting standards. The JOBS Act provides that a company can elect to opt out of the extended transition period and comply with the requirements that apply to non-emerging growth companies but any such choice to opt out is irrevocable. The Company has elected to opt out of the extended transition periods.

**Concentration of Risk**

The Department of Energy has contributed 98% and the NIH has contributed 2% of all grant reimbursements for the six months ended June 30, 2025. The Company believes it is not exposed to significant credit risk on government grant funding, based on the nature of eXoZymes' grant receivables.

**Revenue Recognition**

The Company primarily generated revenues from its strategic alliances. The strategic alliances with strategic collaborators typically contain multiple elements, including research and other licenses, research and development services, obligations to develop and manufacture pre-commercial and commercial material, and options to obtain additional research and development services. Such arrangements provide for various types of payments to us, including upfront fees, and funding of research and development services. Such payments are often not commensurate with the timing of revenue recognition and therefore result in deferral of revenue recognition.

The Company analyzes the collaboration arrangements to assess whether they are within the scope of ASC Topic 808, Collaborative Arrangements (ASC 808) to determine whether such arrangements involve joint operating activities performed by parties that are both active participants in the activities and exposed to significant risks and rewards that are dependent on the commercial success of such activities. To the extent the arrangement is within the scope of ASC 808, the Company assesses whether aspects of the arrangement between the Company and the collaboration partner are within the scope of other accounting literature. If the Company concludes that some or all aspects of the arrangement represent a transaction with a customer, the Company accounts for those aspects of the arrangement within the scope of ASC 606. If the Company concludes that some or all aspects of the arrangement are within the scope of ASC 808 and do not represent a transaction with a customer, the Company recognizes its allocation of the shared costs incurred with respect to the jointly conducted activities as a component of the related expense in the period incurred. Pursuant to ASC 606, a customer is a party that has contracted with an entity to obtain goods or services that are an output of the entity's ordinary activities in exchange for consideration. Under ASC 606, an entity recognizes revenue when its customer obtains control of promised goods or services, in an amount that reflects the consideration which the entity expects to receive in exchange for those goods or services.

To determine the appropriate amount of revenue to be recognized for arrangements that the Company determines are within the scope of ASC 606, the Company performs the following steps: (i) identify the contract(s) with the customer; (ii) identify the performance obligations in the contract; (iii) determine the transaction price; (iv) allocate the transaction price to the performance obligations in the contract; and (v) recognize revenue when (or as) each performance obligation is satisfied. ASC 606 requires significant judgment and estimates and results in changes to, but not limited to: (i) the determination of the transaction price, including estimates of variable consideration, (ii) the allocation of the transaction price, including the determination of estimated selling price, and (iii) the pattern of recognition, including the application of proportional performance as a measure of progress on service-related promises and application of point-in-time recognition for supply-related promises.

**Cash and Cash Equivalents**

The Company considers highly liquid investments with original maturities or remaining maturities upon purchase of six months or less to be cash equivalents. There were $6,985,858 cash and cash equivalents held by the Company as of June 30, 2025.

The Company's policy is to maintain its cash balances with financial institutions with high credit ratings and in accounts insured by the Federal Deposit Insurance Corporation (the "FDIC").

The Company periodically reviews the financial condition of the financial institutions and assesses the credit risk of such investments. The Company may periodically have cash balances in financial institutions more than the FDIC insurance limits of $250,000. On June 30, 2025, the Company had approximately $6,735,858 of cash and unrestricted cash in financial institutions exceeding FDIC insured limits. The Company did not experience any credit risk losses during the six months ended June 30, 2025, and the year ended December 31, 2024.

**Fair Value Measurements**

Fair value is defined as the price that would be received for sale of an asset or paid for transfer of a liability, in an orderly transaction between market participants at the measurement date. GAAP establishes a three-tier fair value hierarchy, which prioritizes the inputs used in measuring fair value. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to unobservable inputs (Level 3 measurements). These tiers include:

● Level 1, defined as observable inputs such as quoted prices (unadjusted) for identical instruments in active markets;

● Level 2, defined as inputs other than quoted prices in active markets that are either directly or indirectly observable such as quoted prices for similar instruments in active markets or quoted prices for identical or similar instruments in markets that are not active; and

● Level 3, defined as unobservable inputs in which little or no market data exists, therefore requiring an entity to develop its own assumptions, such as valuations derived from valuation techniques in which one or more significant inputs or significant value drivers are unobservable.

In some circumstances, the inputs used to measure fair value might be categorized within different levels of the fair value hierarchy. In those instances, the fair value measurement is categorized in its entirety in the fair value hierarchy based on the lowest level input that is significant to the fair value measurement.

The following tables set forth the fair value of the Company's consolidated financial instruments that were measured at fair value on a recurring basis as of June 30, 2025 and December 31, 2024:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **June 30, 2025** | **June 30, 2025** | **June 30, 2025** | **June 30, 2025** |
|  | **Level 1** | **Level 2** | **Level 3** | **Total** |
| Cash and cash equivalents | 6985858 |  |  | 6985858 |
| Total fair value | 6985858 |  |  | 6985858 |

---

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **December 31, 2024** | **December 31, 2024** | **December 31, 2024** | **December 31, 2024** |
|  | **Level 1** | **Level 2** | **Level 3** | **Total** |
| Safe Note |  |  |  |  |
| Total fair value |  |  |  |  |

---

The fair value of the Company's certain assets and liabilities, which qualify as financial instruments under ASC 820, "Fair Value Measurements and Disclosures," approximates the carrying amounts represented in the accompanying condensed unaudited consolidated balance sheets. The fair values of cash and cash equivalents, prepaid expenses and other, accounts payable and accrued expenses, and due to related party are estimated to approximate the carrying values as of June 30, 2025 and December 31, 2024.

**Property and Equipment**

Property and equipment are recorded at cost. Major improvements are capitalized, while maintenance and repairs are charged to expense as incurred. Gains and losses from disposition of property and equipment are included in the statement of operations when realized. Depreciation is provided using the straight-line method over the following estimated useful lives:

Laboratory equipment 5 years <br> Furniture and fixtures 7 years <br> Leasehold improvements Lesser of the lease duration or the life of the improvements

Property and equipment consist of the following as of June 30, 2025, and December 31, 2024, respectively:

---

| | | |
|:---|:---|:---|
|  | **June 30, 2025** | **December 31, 2024** |
| Laboratory equipment | 1348316 | 1277647 |
| Furniture and fixtures | 54338 | 54338 |
| Leasehold improvements | 290111 | 279161 |
| Total property and equipment | 1692765 | 1611146 |
| Less: Accumulated depreciation | (871460) | (728701) |
| Property and equipment, net | 821305 | 882445 |

---

**Research Grants**

eXoZymes receives grant reimbursements from the Federal government, which are offset against research and development expenses in the consolidated statements of operations. In addition to actual reimbursements, eXoZymes also receives indirect expense grants (which are not reimbursement-based) and fees (typically of minor significance). It is important to note that there may be instances where the grants received for indirect costs exceed the actual costs, resulting in a negative impact. For capitalized assets, grant reimbursements are recognized over the useful life of the assets. Any portion of the grant not yet recognized is recorded as deferred grant reimbursements and included as a liability in the consolidated balance sheet.

Grants that operate on a reimbursement basis are recognized on the accrual basis and are offsets to expenses to the extent of disbursements and commitments that are reimbursable for allowable expenses incurred as of the six months ended June 30, 2025 and 2024, and respectively, expected to be received from funding sources in the subsequent year. Management considers such receivables on June 30, 2025 and 2024, respectively, to be fully collectable due to the historical experience with the Federal Government of the United States of America. Accordingly, no allowance for credit losses on the grants receivable was recorded in the accompanying condensed unaudited consolidated financial statements.

Summary of grants receivable activity for the six months ended June 30, 2025 and 2024, is presented below:

---

| | | |
|:---|:---|:---|
|  | **Six Months ended June 30,** | **Six Months ended June 30,** |
|  | **2025** | **2024** |
| Balance at beginning of period | 737282 | 882319 |
| Grant costs expensed | 864433 | 1272127 |
| Grants for equipment purchased | 19699 | 6379 |
| Grant fees | 8715 | 39372 |
| Grant funds received | (1372722) | (1053026) |
| Balance at end of period | 257407 | 1147171 |

---

eXoZymes has received three grants provided by the National Institutes of Health, the Department of Energy and Department of Defense through June 30, 2025. The first grant was awarded on October 1, 2023 and the latest of these grants was set to expire on May 14, 2026, however grants can be extended, or new phases can be granted, extending the expiration of the grant. None of the grants has commitments made by the parties, provisions for recapture, or any other contingencies, beyond complying with the terms of each research and development grant. Research grants received from organizations are subject to the contract agreement as to how eXoZymes conducts its research activities, and eXoZymes is required to comply with the agreement terms relating to those grants. Amounts received under research grants are nonrefundable, regardless of the success of the underlying research project, to the extent that such amounts are expended in accordance with the approved grant project. eXoZymes is permitted to draw down the research grants after incurring the related expenses.

Amounts received under research grants are offset against the related research and development costs in the consolidated statements of operations. For the six months ended June 30, 2025 and 2024, respectively, grants amounting to $864,433 and $1,272,127 were offset against the research and development costs. Grant drawdowns, which includes grants costs expensed, grants for equipment purchased, and grant fees, for the six months ended June 30, 2025 and 2024, respectively, totaled $892,847 and $1,317,878.

For the three months ended June 30, 2025 and 2024, respectively, grants amounting to $292,611 and $597,969 were offset against the research and development costs. Grant drawdowns, which includes grants costs expensed, grants for equipment purchased, and grant fees, for the three months ended June 30, 2025 and 2024, respectively, totaled $317,066 and $609,178.

**Research and Development Costs**

Research and development costs are expensed as incurred. Research and development costs consist primarily of compensation costs, fees paid to consultants, and other expenses relating to the development of eXoZymes's technology. For the six months ended June 30, 2025 and 2024, research and development costs prior to offset of the grants amounted to $2,268,677, and $1,832,855, respectively, which includes grant costs expensed, grants fees, and research and development costs, net of the grant received.

For the three months ended June 30, 2025 and 2024, research and development costs prior to offset of the grants amounted to $1,120,057, and $846,573, respectively, which includes grant costs expensed, grants fees, and research and development costs, net of the grant received.

**Patent and Licensing Legal and Filing Fees and Costs**

Due to the significant uncertainty associated with the successful development of one or more commercially viable products based on the research efforts and related patent applications, all patent and licensing legal and filing fees and costs related to the development and protection of its intellectual property are charged to operations as incurred.

Patent and licensing legal and filing fees and costs were $148,528 and $104,760 for the six months ended June 30, 2025 and 2024, respectively. Patent and licensing legal and filing fees and costs are included in general and administrative costs in the consolidated statements of operations.

**Related Party and Due to Affiliates Expenses**

As of June 30, 2025, the Company had an outstanding receivable of $346 from MDB Capital Holdings, LLC. The receivable is non-interest bearing and will be collected in 2025.

**Segment Reporting**

We manage and operate the business as a single reportable operating segment**, w**ith the Company's sole focus on the research and commercialization of exozyme biosolutions. Our business is led by our chief executive officer, who is our Chief Operating Decision Maker ("CODM"). The Company is required to apply the guidance in ASC 280 and identify significant segment expenses and other segment items for its single reportable segment. Because the CODM receives detailed financial reports at a lower level than is included on the Company's consolidated income statement, the Company identifies which of those expenses qualify as significant segment expenses. The CODM manages the business on a consolidated basis and uses consolidated net income as reported on its income statement to allocate resources and assess performance. In accordance with ASC 280, eXoZymes concludes that consolidated net income is the measure of segment profit or loss that is required to be reported because it is the measure determined in accordance with measurement principles most consistent with GAAP. We do not prepare discrete financial information with respect to separate products. Accordingly, we view our business as one reportable operating segment.

**3. Equity**

***Equity***

In April 2022, pursuant to an equity subscription agreement the Company sold a total of 1,642,345 shares of eXoZymes's Common Stock for $5,000,000 at $3.04 per share. In connection with the equity subscription agreement, the Company issued warrants ("Funding Warrants") to purchase 98,814 shares of eXoZymes Common Stock. Through June 30, 2025 and December 31, 2024, respectively, 205,293 and 205,293 of Funding Warrants have vested. Total value of the warrants as June 30, 2025 and December 31, 2024 was $320,790.

In November 2024, the Company completed a private placement ("Concurrent Private Offering") concurrently with the IPO, the Company sold to accredited investors an aggregate of 93,750 warrants to purchase up to 93,750 shares of Common Stock (the "Private Warrants"). The Private Warrants were sold at a purchase price of $0.125. The Private Warrants have an exercise price of $8.00 per share, are exercisable beginning six months after issuance, and expire five years from the date of issuance. The Private Warrants have a cashless exercise provision and registration rights for the underlying shares of Common Stock. The gross proceeds from the Concurrent Private Offering were approximately $11,719, and if the Private Warrants are fully exercised, for cash, the Company will receive up to $750,000.

In November 2024, the Company issued warrants to underwriters in connection with the IPO. The Company issued 52,485 warrants with an exercise price of $10.00 per share. The warrants are exercisable, beginning six months after issuance, and expire five years from the date of issuance. The underwriter warrants have a cashless exercise provision and registration rights for the underlying shares of Common Stock.

The warrants outstanding, issued, exercised, and expired, along with their respective exercise prices and expiration dates, as of December 31, 2024, and for the six months ended June 30, 2025 is presented below:

---

| | | | |
|:---|:---|:---|:---|
| **Description** | **Number of Warrants** | **Exercise Price** | **Expiration Date** |
| Balance at 12/31/2024 | 351528 | 4.75 | Various (2029) |
| Issued |  |  |  |
| Exercised |  |  |  |
| Expired |  |  |  |
| Balance at 6/30/2025 | 351528 | $4.75 (weighted avg) | Various (2029) |

---

On May 12, 2025, the Company agreed to issue 19,440 shares of common stock to key executives. The shares were issued in lieu of cash bonuses and were issued at a market price of $12.54 for a total of $243,778.

**4. Stock-Based Compensation**

eXoZymes' 2020 Equity Incentive Plan (the "2020 Plan"), which was approved by the eXoZymes shareholders, permits grants to its officers, directors, and employees for up to 938,832 shares of eXoZymes' Common Stock. On May 1, 2023 the board and shareholders approved an increase of 1,558,175 shares under the plan. The 2020 Plan authorizes the issuance of stock options, shares of restricted stock, and restricted stock units, among other forms of equity-based awards.

On February 1, 2024, stock options to purchase 155,818 shares of Common Stock were granted at an exercise price of $3.32 per share, which was equal to the fair value of the Common Stock on the date of grant and are exercisable for a period of 7 years. The stock options vest ratably over a period of 5 years. The inputs used to determine the fair value was Common Stock price of $3.32, option exercise price of $3.32, expected life in years of 5 years, with a contract life of 7 years, risk-free rate of 4.20%, expected annual volatility of 95.85%, and annual rate of dividends of $0.

On April 1, 2024, stock options to purchase 125,975 shares of Common Stock were granted at an exercise price of $8.00 per share, which was equal to the fair value of the Common Stock on the date of grant and are exercisable for a period of 7 years. The stock options vest ratably over a period of 5 years. The inputs used to determine the fair value was Common Stock price of $8.00, option exercise price of $8.00, expected life in years of 5 years, with a contract life of 7 years, risk-free rate of 4.34%, expected annual volatility of 95.38%, and annual rate of dividends of $0.

On May 19, 2024, 2,347 stock options were exercised using a cashless exercise option. The individual received a stock option grant of 5,194 shares of which 3,376 shares were vested and exercisable. 1,029 shares were sold using a cashless exercise option to acquire the remaining 2,347 shares. The remaining unvested options totaling 1,818 shares were forfeited.

On June 1, 2024, stock options to purchase 444,076 shares of Common Stock were granted at an exercise price of $8.00 per share, which was equal to the fair value of the Common Stock on the date of grant and are exercisable for a period of 7 years. The stock options vest ratably over a period of 5 years. The inputs used to determine the fair value was Common Stock price of $8.00, option exercise price of $8.00, expected life in years of 5 years, with a contract life of 7 years, risk-free rate of 4.52%, expected annual volatility of 94.78%, and annual rate of dividends of $0.

On December 20, 2024, two individuals exercised their options agreements. Both agreements had identical terms and were exercised on the same date. Each agreement exercised 2,597 stock options using a cashless exercise option. 1,200 shares were sold using a cashless exercise option to acquire the remaining 1,397 shares. There were no remaining unvested options to be forfeited.

As of June 30, 2025, stock options to purchase 557,840 shares of Common Stock were vested, the weighted average exercise price is $6.07, the aggregate intrinsic value is $6,980,242, and the weighted average remaining contractual term is 6.12 years. The stock options were issued in 2021, 2023 and 2024 and had a vesting term of five years with an expiry of seven years. eXoZymes stock-based compensation were $640,753 and $491,085 for the six months ended June 30, 2025 and 2024. As of June 30, 2025, the unrecognized stock-based compensation is $3,194,925.

A summary of stock option activity during the six months ended June 30, 2025 and December 31, 2024 is presented below:

---

| | | | |
|:---|:---|:---|:---|
|  | **Number of<br> Shares** | **Weighted<br> Average<br> Exercise Price** | **Weighted<br> Average Remaining Contractual<br> Life (in Years)** |
| Stock options outstanding at December 31, 2024 | 1747789 | 4.66 | 6.13 |
| Granted |  |  |  |
| Exercised |  |  |  |
| Expired | 311636 | 2.44 | 2.59 |
| Stock options outstanding at June 30, 2025 | 1436153 | $6.07 | 6.12 |
| Stock options exercisable at June 30, 2024 | 378445 | $4.59 | 5.91 |
| Stock options exercisable at June 30, 2025 | 557840 | $6.07 | 6.12 |

---

On July 19, 2021, eXoZymes granted 82,118 restricted stock units ("RSUs") at a value of $2.44 per share. These RSUs were issued in 2020 in lieu of cash bonuses. As these RSUs do not vest until the expiration of any lock up after an initial public offering of the Company, or upon the change of control of the Company by eXoZymes, which is outside of the control of the Company, no compensation expense related to these RSUs has been recorded. These RSUs fully vest upon the expiration of any lockup period on November 11, 2025, or upon the change of control of eXoZymes. The Company will record stock-based compensation for these RSUs when the RSUs begin to vest, and the unrecognized stock-based compensation is $164,236.

On March 28, 2022, eXoZymes granted 241,718 restricted stock units ("RSUs") at a value of $2.44 per share. These RSUs were issued in 2021 in lieu of cash bonuses. As these RSUs do not vest until the expiration of any lock up after an initial public offering of the Company, or upon the change of control of the Company by eXoZymes, which is outside of the control of the Company, no compensation expense related to these RSUs has been recorded. These RSUs fully vest upon the expiration of any lockup period on November 11, 2025, or upon the change of control of eXoZymes. The Company will record stock-based compensation for these RSUs when the RSUs begin to vest, and the unrecognized stock-based compensation is $588,709.

On May 1, 2023, eXoZymes granted 100,820 restricted stock units ("RSUs") at a value of $3.32 per share. These RSUs were issued in 2023 in lieu of cash bonuses. As these RSUs do not vest until the expiration of any lock up after an initial public offering of the Company, or upon the change of control of the Company by eXoZymes, which is outside of the control of the Company, no compensation expense related to these RSUs has been recorded. These RSUs fully vest upon the expiration of any lockup period, on November 11, 2025, or upon the change of control of eXoZymes. The Company will record stock-based compensation for these RSUs when the RSUs begin to vest, and the unrecognized stock-based compensation is $334,711.

---

| | | | |
|:---|:---|:---|:---|
|  | **Number of** <br> **Restricted** <br> **Stock Units** | **Weighted** <br> **Average** <br> **Grant Date** <br> **Fair Value** | **Weighted** <br> **Average** <br> **Remaining Contractual**<br> **Life (in Years)** |
| Restricted stock units outstanding at December 31, 2024 | 424656 | $2.64 | 8.04 |
| Granted |  |  |  |
| Exercised |  |  |  |
| Expired |  |  |  |
| Forfeited | - | - | - |
| Restricted stock units outstanding at June 30, 2025 | 424656 | $2.64 | 7.12 |
| Restricted stock units at June 30, 2024 | 424656 | $2.64 | 8.62 |
| Restricted stock units at June 30, 2025 | 424656 | $2.64 | 7.37 |

---

**5. Earnings Per Share**

The Company's computation of earnings (loss) per share ("EPS") includes basic and diluted EPS. Basic EPS is measured as the income (loss) attributable to holders of the Common Stockholders divided by the weighted average of the common shares outstanding for the period. Diluted EPS is like basic EPS but presents the dilutive effect on a per share basis of potential common shares (e.g., preferred shares, warrants and stock options) as if they had been converted at the beginning of the periods presented, or issuance date, if later. Potential common shares that have an anti-dilutive effect (i.e., those that increase income per share or decrease loss per share) are excluded from the calculation of diluted EPS.

Loss per common share is computed by dividing net loss by the weighted average number of shares of Common Stock outstanding during the respective periods. Basic and diluted loss per common share was the same for all periods presented because warrants, RSU's and options outstanding were anti-dilutive, for a total of 2,066,102 and 977,468 shares, respectively.

Basic and fully diluted earnings (loss) per share is calculated as follows for the six months ended June 30, 2025 and 2024:

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| | | |
|:---|:---|:---|
|  | **June 30, 2025**<br>**Common shares** | **June 30, 2024**<br>**Common shares** |
| Net loss | (4216708) | $(2368988) |
| Weighted average shares outstanding – basic and diluted | 8372564 | 6250557 |
| Net loss per share – basic and diluted | (0.50) | $(0.38) |

---

The following financial instruments were not included in the diluted loss per share calculations as of the six months ended June 30, 2025 and 2024 because their effect was anti-dilutive:

---

| | | |
|:---|:---|:---|
|  | **June 30, 2025** | **June 30, 2024** |
| Warrants to purchase common stock | 205293 | 205293 |
| Options | 1436153 | 378445 |
| Restricted stock awards units | 424656 | 424656 |
| Total | 2066102 | 1008394 |

---

**6. Commitments and Contingencies**

**Legal Claims**

The Company may be subject to legal claims and actions from time to time as part of its business activities. As of June 30, 2025 and 2024, the Company was not subject to any pending or threatened legal claims or actions.

**External Risks Associated with the Company's Business Activities**

***<u>Inflation Risk</u>.*** The Company does not believe that inflation has had a material effect on its operations to date, other than its impact on the general economy.

***<u>Supply Chain Issues</u>.*** As of June 30, 2025, the Company continues to monitor changes in tariffs and indirect trade restraints and does not believe they will have a significant impact on its business activities.

***<u>Potential Recession</u>.*** There are various indications that the United States economy may be entering a recessionary period. Also, there is possible economic instability due to the possibility of tariffs and other economic changes due to government policy of the United States and other countries. Although unclear at this time an economic recession would likely impact the general business environment and the capital markets, which could, in turn, affect the Company.

The Company is continuing to monitor these matters and will adjust its current business and financing plans as more information and guidance become available.

**7. Employee Benefit Plans**

eXoZymes sponsors an individual 401(k) defined contribution plan for the benefit of employees when eligible. The plan allows eligible employees to contribute a portion of their annual compensation, not to exceed annual limits for the employee as established by the Department of Treasury. eXoZymes makes matching contributions for participating employees up to a certain percentage of the employee contributions; matching contributions were funded for the six months ended June 30, 2025 and 2024. Benefits under this plan were available to all employees, and employees become fully vested in the employer's contribution upon receipt. A total of $80,188 and $56,692 were contributed to the 401 (k) plan for the six-months ended June 30, 2025 and 2024, respectively.

eXoZymes also provides health and related benefit plans for eligible employees.

**8. Exclusive License Agreement (eXoZymes)**

On April 19, 2019, eXoZymes entered into a license agreement (the "License Agreement") with The Regents of the University of California ("The Regents") for patent rights and associated technology relating to the biosynthetic platform being developed by the Company. Certain individuals named as inventors of the patent rights are also the founding stockholders of eXoZymes. One of the founders of eXoZymes was the head of the laboratory which was used in the research and development of patents and associated technology subject to the agreement with The Regents.

Under the License Agreement, eXoZymes holds an exclusive license of the patent rights and a non-exclusive license for the associated technology to make, have made, use, have used, sell, have sold, offer for sale, and import licensed products in the field of use. Under the License Agreement, eXoZymes paid an initial license fee and is to pay an annual license fee and royalties on net sales, a minimum annual royalty that is credited against the royalties on net sales, and a percentage of any sublicensing income. The net income royalty commences after the first commercial sale of a licensed product. As of June 30, 2025, there were no accrued royalties recorded.

Under the License Agreement, eXoZymes is required to achieve certain development milestones. eXoZymes is obligated to make payments upon achievement of certain sales thresholds, as defined in the License Agreement. As of June 30, 2025 the development milestones have been met.

The following net sales milestone payments have not yet been incurred. The net sales milestones do not have a deadline and are listed below as of June 30, 2025.

● A payment of $250,000 when a licensed product reaches $1,000,000 in cumulative net sales.

● A payment of $350,000 when a second licensed product reaches $2,000,000 in cumulative net sales.

The Regents have the right terminate the License Agreement for breaches of the License Agreement by eXoZymes

eXoZymes may terminate the License Agreement, in whole or in part as to a particular patent right, at any time by providing notice of termination to The Regents as defined in the License Agreement.

The payments made to the Regents in connection with our license agreement with the Regents, from 2019 to June 30, 2025, has aggregated $390,409. This includes payments for patent fees associated with the license and maintenance fees.

Under the License Agreement, the Company also issued 249,689 shares of Common Stock, then representing four percent of its common equity, as initial consideration.

eXoZymes accounts for the costs incurred in connection with the License Agreement in accordance with ASC Topic 730, Research and Development. The Company paid license fees for the six months ended June 30, 2025 and 2024, respectively, of $4,513 and $2,007.

**9. Leases**

For operating leases, the Company records right-of-use assets and corresponding lease liabilities in the consolidated balance sheets for all leases with terms longer than twelve months. The Company has two operating leases, with no variable lease costs, and one finance lease as of June 30, 2025.

On April 3, 2023, the Company executed a lease for new office space next to the existing space at eXoZymes in the Los Angeles, California metropolitan area. The lease with a term of 60 months began on July 1, 2023 and ends on June 30, 2028, without an option to extend. The initial base rent was $13,277 per month. The lease provides for annual increases. The base rent for the lease in the final year is $14,943 per month.

In April 2023, eXoZymes made changes to an existing lease agreement, which resulted in an extension of the lease term by an additional 21 months. The revised lease maintained the same escalation rate for lease payments as the previous arrangement. To account for this modification, the Company reevaluated the remaining lease term at the time of execution. As the Company was actively utilizing the premises, adjustments were made to reflect the revaluation of both the right-to-use asset and the corresponding lease liability in line with the updated lease term. This was originally entered into in August 2021, with a term of 60 months beginning on May 1, 2023 and ending on April 30, 2028, with an option to extend for 60 additional months. At the time the lease commenced, it was not probable the Company would exercise the one five-year option to extend the facility lease; therefore, this extension option is not included in the lease analysis. The initial base rent is $14,371 per month. The lease provides for annual increases. The base rent for the lease in the final year is $16,259 per month. Additionally, eXoZymes is responsible for annual operating cost increases of 2.5%, which are included in the rent.

On October 30, 2023, the Company executed an addendum to the current lease for additional office space in Monrovia, California, the expected occupancy of the additional space was May 1, 2023. The lease adds a term of 20 months to the current term for a total of 72 months for the current term, the additional space is for 72 months, both spaces will expire on April 30, 2028 without an option to extend. The expansion space will have an initial base rent of $13,277 per month, along with the current lease of $14,371 per month for the current leased space for a new total of $27,648. The lease provides for annual increases. The base rent for the lease in the final year is $15,391 per month for the expansion space and $16,747 for the current space for a total of $32,138.

eXoZymes entered into a 36-month equipment lease with Thermo Fisher Scientific in December 2024 for medical equipment to be used in research and development. The Company took possession of the equipment in May 2025. The lease agreement provides for a purchase option at the end of the lease term for a purchase value of the then fair market value of the equipment.

Discussions with management indicate that it is unlikely that the purchase option will be exercised at the end of the lease term. Some contributing factors to this decision include the uncertainty of the purchase price and the possible changes in technology over the next three years. Accordingly, an assumed purchase option is not included in the calculation of the total lease liability.

The fair value of the equipment is documented in the lease agreement as $146,642 at the inception of the lease. Management does not believe there is any change in fair value from the inception date to the commencement date. The Company has used its assumed incremental borrowing rate (IBR) to determine the present value of future rent payments. The assumed rate is 7.54% and is also equal to the IBR used in its operating lease for office space. The resulting present value is $136,391 or 93% of the asset's fair value.

ROU assets represent the Company's right to use an underlying asset for the lease term, and lease liabilities represent the Company's obligation to make lease payments. Operating lease ROU assets and liabilities are recognized at the lease commencement date based on the present value of lease payments over the lease term. The Company uses the implicit rate in its lease calculations when it is readily determinable. Since the Company's leases do not provide implicit rates, to determine the present value of lease payments, management uses the Company's estimated incremental borrowing rate for a fully collateralized loan with a similar term of the lease that is based on the information available at the inception of the lease.

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| | | |
|:---|:---|:---|
|  | **June 30, 2025** | **December 31, 2024** |
| **Operating leases:** |  |  |
| &nbsp;&nbsp;&nbsp;Right-of-use assets | $1194981 | $1331577 |
| &nbsp;&nbsp;&nbsp;Operating lease liabilities | $1264863 | $1386832 |
| &nbsp;&nbsp;&nbsp;Weighted average remaining lease term in years | 4.08 | 4.58 |
| &nbsp;&nbsp;&nbsp;Weighted average discount rate | 7.58% | 7.58% |
| &nbsp;&nbsp;&nbsp;Cash paid for amounts of operating lease | $172638 | $339576 |
| **Finance leases:** |  |  |
| &nbsp;&nbsp;&nbsp;Right-of-use assets | $129593 | $- |
| &nbsp;&nbsp;&nbsp;Finance lease liabilities | $129593 | $- |
| &nbsp;&nbsp;&nbsp;Weighted average remaining lease term in years | 2.75 |  |
| &nbsp;&nbsp;&nbsp;Weighted average discount rate | 7.54% |  |
| &nbsp;&nbsp;&nbsp;Amortization of assets under finance lease | $6798 | $- |
| &nbsp;&nbsp;&nbsp;Interest | $1693 |  |

---

For the six months ended June 30, 2025, and 2024, the Company recognized operating lease expenses of $187,265 in each period. Finance lease payments totaled $8,491 for the six months ended June 30, 2025, with no finance lease payments made during the comparable period in 2024.

As of June 30, 2025, the future minimum lease payments under non-cancelable operating and finance leases are as follows:

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| | | |
|:---|:---|:---|
| **Year** | **Operating Leases** | **Finance Leases** |
| 2025 | 176235 | 25471 |
| 2026 | 358428 | 50941 |
| 2027 | 368250 | 50941 |
| 2028 | 378576 | 16980 |
| Thereafter | 192828 | - |
| Total | $1474317 | $144333 |
| Less effects of discounting | (209454) | (14740) |
| Total lease liabilities | $1264863 | $129593 |

---

**10. Subsequent Events**

On July 1, 2025, the eXoZymes board approved an issuance of stock options to purchase 235,817 shares of common stock and were granted at an exercise price of $12.69 per share, which was equal to the fair value of the common stock on the date of grant and are exercisable for a period of 7 years. The stock options vest ratably over a period of 4 years.

On July 1, 2025, the Company was awarded a key industrial partnership, with a $3 million share of a $9.2 million grant. U.S. National Science Foundation (NSF) funded the project under the CFIRE program aimed at transforming the scalability and accessibility of cell-free systems to expand real-world applications. The grant is led by <u>Georgia Tech</u> with a coalition of top academic and industry groups.

On July 25, 2025 the Company's shareholders approved, by a majority, the "2025 equity incentive plan". The new plan allows for an additional 1,250,000 shares to be added to the equity incentive pool.

The Company has evaluated subsequent events through August 12, 2025, the date on which these financial statements were issued.

**ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS**

**Overview**

eXoZymes is a biotechnology, pre-revenue, development stage company. Management believes that eXoZymes's technology is a differentiated and unique synthetic biology platform. Management believes the platform will enable scalable production of chemical molecules found in nature in a process that is alternative to and more environmentally friendly and sustainable than the typical methods used today, such as chemical synthesis, natural extraction, and synthetic biology. eXoZymes believes its technology could significantly change biomanufacturing through leveraging cell-free, multi-step enzyme-based systems that will be able to transform natural or renewable resources into sought after chemicals. The objective with the eXoZymes synthetic biology platform, as it is developed over time, for diverse range of select chemicals will enable the production of pharmaceuticals, fuels, materials, food additives, and novel compounds.

**Results of Operations**

The Company has determined its reporting units in accordance with ASC (Accounting Standards Codification) 280, Segment Reporting. The Company has one reportable segment for eXoZymes as a whole. A single management team that reports to the Chief Executive Officer comprehensively manages the business. Accordingly, the Company does not have separately reportable segments.

The Company's consolidated statements of operations as discussed herein are presented below.

**<u>Consolidated Results of Operations for the Six months Ended June 30, 2025 and 2024</u>**

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Six Months ended June 30,** | **Six Months ended June 30,** | | |
|  | **2025** | **2024** |<br>**$ Change** |<br>**% Change** |
| Total operating income | $- | $- |  | 0.0% |
| Operating costs: |  |  |  |  |
| General and administrative costs: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Compensation | 1682762 | 1121651 | 561111 | 50.0% |
| &nbsp;&nbsp;&nbsp;Professional fees | 901167 | 546466 | 354701 | 64.9% |
| &nbsp;&nbsp;&nbsp;Information technology | 67152 | 13606 | 53546 | 393.5% |
| &nbsp;&nbsp;&nbsp;General and administrative-other | 469689 | 140362 | 329327 | 234.6% |
| Total general and administrative costs | 3120770 | 1822085 | 1298685 | 71.3% |
| Research and development costs, net of grants amounting to $864,433 and $1,317,878, for the six months ended June 30 | 1378003 | 514977 | 863026 | 167.6% |
| Total operating costs | 4498773 | 2337062 | 2161711 | 92.5% |
| Net operating loss | (4498773) | (2337062) | (2161711) | 92.5% |
| Other income/(expense): |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Interest income/ (expense) | 170864 | (29782) | 200646 | -673.7% |
| &nbsp;&nbsp;&nbsp;Other income: | 111202 | - | 111202 | 100.0% |
| Loss before income taxes | (4216707) | (2366844) | (1849863) | 78.2% |
| Income taxes | - | (2144) | 2144 | 100.0% |
| Net loss | $(4216707) | $(2368988) | (1847719) | 78.0% |

---

**<u>General and Administrative Costs</u>**.

During six months ended June 30, 2025, and 2024, respectively, several factors contributed to changes in various expense categories:

● Compensation Expense: The increase in compensation expense during the six months ending June 30, 2025, resulted from the recruitment of additional staff, who are not covered by grants. This was accompanied by increases in compensation and additional accrual of bonuses compared to six months period ended June 30, 2024

● Professional Fees: The increase in professional fees compared to previous period was due to higher consulting costs related to operations and higher legal, tax, and consulting costs.

● Information Technology Costs: The increase in costs for the six months ending June 30, 2025, were related to additional IT projects to improve the company's infrastructure and operations.

● Other General and Administrative Costs: The increase in costs for the six months ended June 30, 2025, relate to D&O insurance costs and director fees, which did not occur in the six months ended June 30, 2024.

**<u>Research and Development Costs</u>**.

For the six months ended June 30, 2025, research and development costs increased by $863,853 compared to the same period in 2024, primarily due to new hires, higher salary, bonus accruals, stock-based compensation and laboratory expenses, as well as a reduction in grant funding. It is important to note that the decrease in grant funding was not attributable to any specific event.

**<u>Consolidated Results of Operations for the Three months Ended June 30, 2025 and 2024</u>**

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months ended June 30,** | **Three Months ended June 30,** | | |
|  | **2025** | **2024** |<br>**$ Change** |<br>**% Change** |
| Total operating income | $- | $- |  | 0.0% |
| Operating costs: |  |  |  |  |
| General and administrative costs: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Compensation | 1068838 | 731607 | 337231 | 46.1% |
| &nbsp;&nbsp;&nbsp;Professional fees | 368932 | 289903 | 79029 | 27.3% |
| &nbsp;&nbsp;&nbsp;Information technology | 41835 | 9714 | 32121 | 330.7% |
| &nbsp;&nbsp;&nbsp;General and administrative-other | 265449 | 59985 | 205464 | 342.5% |
| Total general and administrative costs | 1745054 | 1091209 | 653845 | 59.9% |
| Research and development costs, net of grants amounting to $317,066 and $331,596, for the three months ended June 30 | 802991 | 237395 | 565596 | 238.3% |
| Total operating costs | 2548045 | 1328604 | 1219441 | 91.8% |
| Net operating loss | (2548045) | (1328604) | (1219441) | 91.8% |
| Other income/(expense): |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Interest income/ (expense) | 76557 | (29782) | 106339 | -357.1% |
| &nbsp;&nbsp;&nbsp;Other income: | 111202 | - | 111202 | 100.0% |
| Loss before income taxes | (2360286) | (1358386) | (1001900) | 73.8% |
| Income taxes | - | (2144) | 2144 | 100.0% |
| Net loss | $(2360286) | $(1360530) | (999756) | 73.5% |

---

**<u>General and Administrative Costs</u>**.

For three months ended June 30, 2025, and 2024, respectively, several factors contributed to changes in various expense categories:

● Compensation Expense: The increase in compensation expenses for the three months ended June 30, 2025, was primarily driven by the hiring of new employees not funded by grants.

● Professional Fees: The increase in professional fees over the prior period was mainly due to higher consulting expenses related to business operations, as well as higher legal and tax fees.

● Information Technology Costs: The higher IT expenses during the three months ended June 30, 2025, were associated with new technology initiatives aimed at enhancing the company's infrastructure.

● Other General and Administrative Costs: The increase in costs for the three months ended June 30, 2025, relate to D&O insurance costs and director fees, which did not occur in the three months ended June 30, 2024.

**<u>Research and Development Costs</u>**.

For the three months ended June 30, 2025, research and development costs increased by $565,596 compared to the same period in 2024, primarily due to higher salary, bonus accruals, stock-based compensation and laboratory expenses, as well as a reduction in grant funding. It is important to note that the decrease in grant funding was not attributable to any specific event.

**<u>Consolidated Balance Sheet as of June 30, 2025 and December 31, 2024</u>**

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **June 30, 2025** | **December 31, 2024** | **$ Change** | **% Change** |
| ASSETS |  |  |  |  |
| Cash and cash equivalents | $6985858 | $9719310 | (2733452) | -28.1% |
| Grants receivable | 257407 | 737282 | (479875) | -65.1% |
| Due from affiliates | 346 |  | 346 | 100% |
| Prepaid expenses and other current assets | 287419 | 363790 | (76371) | -21.0% |
| Total current assets | 7531030 | 10820382 | (3289352) | -30.4% |
| Property and equipment, net | 821305 | 882445 | (61140) | -6.9% |
| Operating lease right-of-use asset, net | 1194981 | 1331577 | (136596) | -10.3% |
| Finance lease right-of-use asset, net | 129593 | - | 129593 | 100.0% |
| Total assets | $9676909 | $13034404 | (3357495) | -25.8% |
| LIABILITIES AND EQUITY |  |  |  |  |
| Accounts payable | $930629 | $924252 | 6377 | 0.7% |
| Due to affiliates |  | 178966 | 178966 | -100.0% |
| Operating lease liabilities – Current | 243691 | 230027 | 13664 | 5.9% |
| Finance lease liabilities – Current | 42623 | - | 43623 | 100.0% |
| Total current Liabilities | 1216943 | 1333245 | (116302) | -8.6% |
| Deferred grant reimbursement | 116119 | 123579 | (7460) | -6.0% |
| Operating lease liabilities - long term | 1021172 | 1156805 | (135633) | -11.7% |
| Finance lease liabilities - long term | 86970 | - | 85970 | 100.0% |
| Total liabilities | $2441204 | $2613629 | (172425) | -6.6% |
| Equity: |  |  |  |  |
| Common shares | 8 | 8 |  | 0.0% |
| Paid-in-capital | 23398362 | 22366725 | 1031637 | 4.6% |
| Accumulated deficit | (16162665) | (11945958) | (4216707) | 35.3% |
| Total equity | 7235705 | 10420775 | (3185070) | -30.6% |
| Total liabilities and equity | $9676909 | $13034404 | (3357495) | -25.8% |

---

***<u>Financial Condition:</u>***

The decrease in assets was due to changes in several asset classes, but primarily in cash and cash equivalents. The decrease in grants receivable was driven by completion of certain grants and timing of grant drawdowns. The decrease in prepaid expenses was due to ongoing amortization of prepaids to expenses. The decrease in property and equipment was due to the ongoing accumulated depreciation of fixed asset. The decrease in operating lease right-of-use assets resulted from the usage and payments of office space during the period.

The decrease in liabilities were primarily driven by the decrease in the amount of Due to affiliates.

The equity decrease was due to losses generated by operations.

**Liquidity and Capital Resources – June 30, 2025 and 2024**

The Company's consolidated statements of cash flows as discussed herein are presented below.

---

| | | |
|:---|:---|:---|
|  | **Six months Ended June 30,** | **Six months Ended June 30,** |
|  | **2025** | **2024** |
| Net cash (used in) operating activities | $(2671532) | $(2256599) |
| Net cash (used in) investing activities | (61920) | (179666) |
| Net cash (used in) by financing activities | - | 2527971 |
| Net increase (decrease) in cash and cash equivalents | $(2733452) | $91706 |

---

On June 30, 2025, the Company had working capital of $6,314,087, as compared to working capital of $9,487,137 on December 31, 2024, reflecting a decrease in working capital of $3,173,050. This decrease in working capital was the result of usage of cash and cash equivalents to fund operations. On June 30, 2025, the Company had cash of $6,985,858 available to fund its operations.

On November 11, 2024, the Company signed a firm commitment underwriting agreement for its IPO, in which it sold an aggregate of 1,987,666 shares of Common Stock, including 112,666 shares pursuant to the underwriter overallotment option, for gross proceeds of $15,901,328, and net proceeds of approximately $15,206,543. The Company used approximately $4,243,022 to repay loans from MDB Capital Holdings, LLC shortly after the closing of the IPO. The balance of the proceeds as of June 30, 2025, will continue to be used, throughout 2025, in the expansion of its production capabilities, staffing, R&D and other working capital requirements.

In a private placement ("Concurrent Private Offering") completed concurrently with the IPO, the Company sold to accredited investors an aggregate of 93,750 warrants to purchase up to 93,750 shares of Common Stock (the "Private Warrants"). The Private Warrants were sold at a purchase price of $0.125. The Private Warrants have an exercise price of $8.00 per share, are exercisable beginning six months after issuance, and expire five years from the date of issuance. The Private Warrants have a cashless exercise provision and registration rights for the underlying shares of Common Stock. The gross proceeds from the Concurrent Private Offering were approximately $11,719, and if the Private Warrants are fully exercised, for cash, the Company will receive up to $750,000.

In October 2024, the Company received a cost share grant from the Department of Defense (DOD) BioMADE initiative to help fund next steps toward cell-free biomanufacturing of isobutanol in the amount of approximately $1,000,000 against our own required expenses of an equal amount.

In March 2025, the Company received an additional grant in the amount of $283,805 from the National Institute of Health (NIH) BioClick. The BioClick grant focuses on a cell free high-throughput platform for engineering of enzymatic group transfer reactions. The Company intends to pursue additional grants from time to time, which if granted to the Company will further improve its working capital position.

Based on its working capital of approximately $6,314,087 as of June 30, 2025, and its program of seeking various grants, the Company believes it has sufficient funds, in the near term, for its currently planned operations. The Company will continue to allocate its available working capital toward advancing its research, development, and commercialization initiatives. If and when it requires capital, it may sell its equity securities, seek institutional and bank funding, and sell or license various of its intellectual property rights. The Company does not have any current arrangements for additional funding, and there is no assurance that it will be able to obtain funding, when needed, on terms that are commercially reasonable.

***<u>Operating Activities.</u>***

For the six months ended June 30, 2025, operating activities utilized cash of $2,671,532, which was driven by an increased research and development activity, as well as increased general and administrative costs.

For the six months ended June 31, 2024, operating activities utilized cash of $2,256,599. This was primarily driven by increased research and development activity, as well as higher general and administrative expenses, which resulted in a deficit for the period. However, this deficit was offset by cash received from related parties.

***<u>Investing Activities</u>.***

For the six months ended June 30, 2025, and 2024, investing activities primarily consisted of the purchase of laboratory equipment.

***<u>Financing Activities</u>.***

For the six months ended June 30, 2025, the Company did not have any cash transaction in financing activities.

For the six months ended June 31, 2024, the Company had cash expenditures that related to the ongoing IPO activities and totaled $112,029 and received $2,640,000 from a related party note.

**Critical Accounting Estimates**

The preparation of financial statements in conformity with general accepted accounting principles in the United States requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. We have identified certain accounting policies as being critical because they require us to make difficult, subjective, or complex judgments about matters that are uncertain. We believe that the judgment, estimates, and assumptions used in the preparation of our condensed unaudited consolidated financial statements are appropriate given the factual circumstances at the time. However, actual results could differ, and the use of other assumptions or estimates could result in material differences in our results of operations or financial condition. Our critical accounting estimates are:

**Accounting for Research Grants**

eXoZymes receives grant reimbursements, which are offset against research and development expenses in the consolidated statements of operations. In addition to actual reimbursements, eXoZymes also receives indirect expense grants (which are not reimbursement-based) and fees (typically of minor significance). It is important to note that there may be instances where the grants received for indirect costs exceed the actual costs. For capitalized assets, grant reimbursements are recognized over the useful life of the assets. Any portion of the grant not yet recognized is recorded as deferred grant reimbursements and included as a liability in the consolidated balance sheet.

Grants that operate on a reimbursement basis are recognized on the accrual basis and are recorded as offsets to expenses, to the extent of disbursements and commitments for allowable expenses incurred as of June 30, 2025, that are expected to be reimbursed in the subsequent period. Management considers the grants receivable as of June 30, 2025, to be fully collectible, based on historical experience with the Federal Government of the United States of America. Accordingly, no allowance for credit losses on grants receivable was recorded in the accompanying condensed unaudited consolidated financial statements.

Research grants received from organizations are subject to the contract agreement as to how eXoZymes conducts its research activities, and eXoZymes is required to comply with the agreement terms relating to those grants. Amounts received under research grants are nonrefundable, regardless of the success of the underlying research project, to the extent that such amounts are expended in accordance with the approved grant project. eXoZymes is permitted to draw down (a process of submitting expenses for reimbursement) the research grants after incurring the related expenses. Amounts received under research grants are offset against the related research and development costs in the Company's consolidated statement of operations.

**Summary of Business Activities and Plans**

On November 11, 2024, the Company signed a firm commitment underwriting agreement for its initial public offering (IPO) with a closing date of November 11, 2024, which consisted of the sale of an aggregate of 1,875,000 shares of Common Stock. The public offering price was $8.00 per share, for gross proceeds of $15,000,000. The underwriter was granted its overallotment option for up to an additional 281,250 shares until December 26, 2024. The net proceeds for the initial public offering with the overallotment were $15,206,543 as of the date of this report. The proceeds will be used for the development of eXoZymes, expansion of production capabilities, increased staff and related expenses, R&D expenses, repayment of a related party loan and other general corporate and working capital requirements.

**External Risks Associated with the Company's Business Activities**

***<u>Inflation Risk</u>.*** The Company does not believe that inflation has had a material effect on its operations to date, other than its impact on the general economy.

***<u>Supply Chain Issues</u>.*** The Company continues to monitor changes in tariffs and indirect trade restraints. The Company does not currently expect that supply chain issues will have a significant impact on its business activities.

***<u>Potential Recession</u>.*** There are various indications that the United States economy may be entering a recessionary period. Also, there is possible economic instability due to the possibility of tariffs and other economic changes due to government policy of the United States and other countries. Although unclear at this time, an economic recession would likely impact the general business environment and the capital markets, which could, in turn, affect the Company.

The Company is continuing to monitor these matters and will adjust its current business and financing plans as more information and guidance become available.

***<u>Technology.</u>*** The Company's endeavors to create and bring new technologies to the market may never come to fruition or might not reach a level of development sufficient for commercial viability. Even if they do achieve a commercial level of development, the acceptance of these technologies within the marketplace is uncertain. There's a possibility that the technologies they develop may not gain widespread or timely acceptance. Moreover, technologies from our Company that undergo regulatory scrutiny, testing, and approval may ultimately fail to receive the necessary approvals from relevant regulatory bodies.

**Trends, Events and Uncertainties**

Other than as discussed above, we are not currently aware of any trends, events or uncertainties that are likely to have a material effect on our financial condition in the near term, although it is possible that new trends or events may develop in the future that could have a material effect on our financial condition.

**ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK**

As a smaller reporting company, we are not required to provide this information.

**ITEM 4. CONTROLS AND PROCEDURES**

**Disclosure Controls and Procedures**

The Company, with the participation of the Chief Executive Officer and VP of Finance, evaluated, as of the end of the period covered by this Quarterly Report on Form 10-Q, the effectiveness of the disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended, or the Exchange Act). Based on that evaluation, and as a result of the material weaknesses in internal control over financial reporting described below, the Chief Executive Officer and VP of Finance concluded that, as of June 30, 2025, the disclosure controls and procedures were not effective at the reasonable assurance level. In light of this fact, the Company has performed additional analyses, reconciliations, and other post-closing procedures and has concluded that, notwithstanding the material weaknesses in the internal control over financial reporting, the condensed unaudited consolidated financial statements for the periods covered by and included in this Quarterly Report on Form 10-Q fairly state, in all material respects, the financial position, results of operations and cash flows for the periods presented in conformity with GAAP.

**Ongoing Remediation of Previously Identified Material Weakness**

The Company is implementing measures designed to ensure that control deficiencies contributing to the previously disclosed material weakness are remediated, such that these controls are designed, implemented, and operating effectively. These remediation actions are ongoing, and they include our expansion of our controls or control designs based on updated enhanced risk assessments. We have redesigned the financial reporting process, to remediate the previously identified material weakness. We expect these changes to materially improve our internal controls.

The weaknesses will not be considered remediated until the applicable controls operate for a sufficient period of time and management has concluded, through testing, that these controls are operating effectively.

**Changes in Internal Control Over Financial Reporting**

Other than the material weakness remediation efforts underway, there were no changes in the internal control over financial reporting identified in connection with the evaluation required by Rule 13a-15(d) and 15d-15(d) of the Exchange Act that occurred during the six months ended June 30, 2025, that have materially affected, or are reasonably likely to materially affect, the internal control over financial reporting.

**Inherent Limitations on Effectiveness of Controls and Procedures**

The Company's management, including the Chief Executive Officer and VP of Finance, believes that disclosure controls and procedures and internal control over financial reporting are designed to provide reasonable assurance of achieving their objectives and are effective at the reasonable assurance level. However, management does not expect that the disclosure controls and procedures or the internal control over financial reporting will prevent or detect all errors and all fraud. A control system, no matter how well conceived and operated, can provide only reasonable, not absolute, assurance that the objectives of the control system are met. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within the company have been detected. The design of any system of controls also is based in part upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will succeed in achieving its stated goals under all potential future conditions. Over time, controls may become inadequate because of changes in conditions, or the degree of compliance with the policies or procedures may deteriorate. Because of the inherent limitations in a cost-effective control system, misstatements due to error or fraud may occur and not be detected.

**PART II — OTHER INFORMATION**

**Item 1. Legal Proceedings**

We are not currently a party to any material legal proceedings, and we are not aware of any pending or threatened litigation that would have a material adverse effect on our business, operating results, cash flows, or financial condition should such litigation be resolved unfavorably. We believe that from time to time we will have commercial disputes arising in the ordinary course of our business.

**Item 1A. Risk Factors**

In addition to the information set forth in this Form 10-Q, you should also carefully review and consider the risk factors contained in our other registration statements, reports and periodic filings with the SEC that could materially and adversely affect our business, financial condition, and results of operations. The risk factors we have identified and discussed, however, do not identify all risks that we face because our business operations could also be affected by additional factors that are not known to us or that we currently consider to be immaterial to our operations.

*Additional Risk Factors*

**Changes to United States tariff and import/export regulations may have an adverse effect on our business, financial condition and results of operations.**

The United States has enacted and continues to enact significant new tariffs, and President Trump has directed various federal agencies to further evaluate key aspects of U.S. trade policy. There has been and are ongoing discussions and commentaries regarding potential significant changes to U.S. trade policies, treaties and tariffs. There exists significant uncertainty about the future relationship between the U.S. and other countries with respect to such trade policies, treaties and tariffs. These developments, or the perception that any of them could occur, may have a material adverse effect on global and domestic economic conditions, whether or not there will be a recession, and the stability of global and domestic financial markets, and may significantly reduce global trade and, in particular, trade between the impacted nations and the U.S. These actions and policies may adversely effect the ability of the Company and our subsidiaries to fund their operations, effect our ability to develop products and work with partner companies and generally carry on our respective businesses. Although it is not yet possible to assess their impact, any of these factors could depress economic activity and restrict access to suppliers or customers, hinder our ability to obtain funding from the government through grants and from investors, and have a material adverse effect on our overall business, financial condition and results of operations.

**Government Action on tariffs and research grants and other funding may impede our ability to conduct our research and to raise capital by and for our partner companies and other clients.**

Early 2025 federal government actions to impose tariffs, to change trade policies, to change immigration policies, and to limit research grants and other forms of federal government funding, including direct government grants and the funding of universities and research enterprises, may cause disruption to our consolidated business activities based on their direct and indirect effect on our partner companies and our clients for our product solutions. Many of these government actions have been only recently implemented, others are being threatened and many will be ongoing. Therefore the full impact has yet to be realized by the Company and its partner companies and clients. Nonetheless, (i) tariffs are likely to increase the cost of doing business in the general economy and to make it more difficult to obtain items where imported equipment is required by our own activities and the activities of our partner companies and clients, (ii) ending or reducing research funding is likely to make it more difficult to find collaborative research partners to work with us and our partner companies as government funding is an indirect support for research and product development activities, and (iii) the curtailment of direct funding will have an immediate adverse impact on our partner companies and clients and their ability to continue their development work based on our solutions. We also believe that as these policies are implemented, it will make raising capital from private investors far more difficult, as they will want to know if the Company will be able to use the proceeds effectively and will be of sufficient amount.

**Item 2. Unregistered Sales of Equity Securities and Use of Proceeds**

None.

**Item 3. Defaults upon Senior Securities**

None.

**Item 4. Mine Safety Disclosures**

Not applicable.

**Item 5. Other Information**

Not applicable.

**Item 6. Exhibits**

The documents listed in the Exhibit Index of this Form 10-Q are incorporated by reference or are filed with this Form 10-Q, in each case as indicated therein (numbered in accordance with Item 601 of Regulation S-K).

**SIGNATURES**

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed in Monrovia, California, on its behalf by the undersigned, thereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  | EXOZYMES INC. | EXOZYMES INC. |
|  | (the "Registrant") | (the "Registrant") |
| Dated: August 12, 2025 | By: | */s/ Michael Heltzen* |
|  |  | Michael Heltzen |
|  |  | President and Chief Executive Officer |
|  |  | (Principal Executive Officer) |
| Dated: August 12, 2025 | By: | */s/ Fouad Nawaz* |
|  |  | Fouad Nawaz |
|  |  | VP of Finance (Principal Financial and Accounting Officer) |

---

**EXHIBIT INDEX**

---

| | |
|:---|:---|
| Exhibit |  |
| Number | Description of Exhibit |
| 31.1 \* | [Certification of Principal Executive Officer, pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.](ex31-1.htm) |
| 31.2 \* | [Certification of Principal Financial and Accounting Officer, pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.](ex31-2.htm) |
| 32.1\*\* | [Certification of Principal Executive Officer, pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.](ex32-1.htm) |
| 32.2\*\* | [Certification of Principal Financial and Accounting, pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.](ex32-2.htm) |
| 101.INS\* | Inline XBRL Instance Document |
| 101.SCH\* | Inline XBRL Taxonomy Schema |
| 101.CAL\* | Inline XBRL Taxonomy Calculation Linkbase |
| 101.DEF\* | Inline XBRL Taxonomy Definition Linkbase |
| 101.LAB\* | Inline XBRL Taxonomy Label Linkbase |
| 101.PRE\* | Inline XBRL Taxonomy Presentation Linkbase |
| 104\* | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). |

---

\* Filed herewith. <br> \*\* Furnished herewith.

## Exhibit 31.1

**Exhibit 31.1**

**CERTIFICATION PURSUANT TO RULE 13a-14(a) and 15d-14(a)**

**UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED**

I, Michael Heltzen, the President and Chief Executive Officer of eXoZymes Inc., hereby certifies that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. I have reviewed this quarterly report on Form 10-Q of eXoZymes Inc. for the quarterly period ended June 30, 2025;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the registrant and have:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5. The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Dated August 12, 2025

---

| | |
|:---|:---|
| By: | */s/ Michael Heltzen* |
|  | **Michael Heltzen**<br> **President and Chief Executive Officer** |

---

## Exhibit 31.2

**Exhibit 31.2**

**CERTIFICATION PURSUANT TO RULE 13a-14(a) and 15d-14(a)**

**UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED**

I, Fouad Nawaz, the VP of Finance of eXoZymes Inc., hereby certifies that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. I have reviewed this quarterly report on Form 10-Q of eXoZymes Inc. for the quarterly period ended June 30, 2025;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the registrant and have:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5. The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Dated August 12, 2025

---

| | |
|:---|:---|
| By: | */s/ Fouad Nawaz* |
|  | **Fouad Nawaz**<br> **VP of Finance** |

---

## Exhibit 32.1

**Exhibit 32.1**

**CERTIFICATION PURSUANT TO SECTION 1350, CHAPTER 63 OF TITLE 18, UNITED STATES CODE, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002**

In connection with the Quarterly Report on Form 10-Q for the quarter ended June 30, 2025 (the "Report") of eXoZymes Inc. (the "Registrant"), as filed with the Securities and Exchange Commission on the date hereof, I, Michael Heltzen, the President and Chief Executive Officer of the Registrant, hereby certify, to the best of my knowledge, that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Registrant.

---

| | |
|:---|:---|
|  | */s/ Michael Heltzen* |
| Name: | Michael Heltzen, |
|  | President and Chief Executive Officer |
| Date: | August 12, 2025 |

---

This certification accompanies this Quarterly Report on Form 10-Q pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference.

## Exhibit 32.2

**Exhibit 32.2**

**CERTIFICATION PURSUANT TO SECTION 1350, CHAPTER 63 OF TITLE 18, UNITED STATES CODE, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002**

In connection with the Quarterly Report on Form 10-Q for the quarter ended June 30, 2025 (the "Report") of eXoZymes Inc. (the "Registrant"), as filed with the Securities and Exchange Commission on the date hereof, I, Fouad Nawaz, the VP of Finance of the Registrant, hereby certify, to the best of my knowledge, that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Registrant.

---

| | |
|:---|:---|
|  | */s/ Fouad Nawaz* |
| Name: | Fouad Nawaz, |
|  | VP of Finance |
| Date: | August 12, 2025 |

---

This certification accompanies this Quarterly Report on Form 10-Q pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference.