# EDGAR Filing Document

**Accession Number:** 0001527599
**File Stem:** 0001193125-25-182671
**Filing Date:** 2025-8
**Character Count:** 2335
**Document Hash:** a80c3b7ba0bb591600cbb28dbc49eb0b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-182671.hdr.sgml**: 20250918

**ACCESSION NUMBER**: 0001193125-25-182671

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250818

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** SYNLOGIC, INC.
- **CENTRAL INDEX KEY:** 0001527599
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 261824804
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** PO BOX 30
- **CITY:** WINCHESTER
- **STATE:** MA
- **ZIP:** 01890
- **BUSINESS PHONE:** 617-659-2802

**MAIL ADDRESS:**
- **STREET 1:** PO BOX 30
- **CITY:** WINCHESTER
- **STATE:** MA
- **ZIP:** 01890

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Mirna Therapeutics, Inc.
- **DATE OF NAME CHANGE:** 20110809

**SYNLOGIC, INC.** 

**PO Box 30** 

**Winchester, Massachusetts 01890** 

August 18, 2025

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attention: Ms. Doris Stacey Gama

**Re: Synlogic, Inc.** 

**Registration Statement on Form S-3** 

**Filed August 8, 2025** 

**File No. 333-289415 (the "Registration Statement")** 

**<u>Acceleration Request</u>**

Ladies and Gentlemen:

In accordance with Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, Synlogic, Inc. (the "Registrant") hereby respectfully requests that the Securities and Exchange Commission accelerate the effective date of the above-referenced Registration Statement to Wednesday, August 20, 2025, at 4:01 p.m., Eastern Time, or as soon as thereafter practicable.

The cooperation of the staff in meeting the timetable described above is very much appreciated.

Please contact Nishant Dharia, Esq. of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., counsel to the Registrant, at (212) 692-8174 with any questions regarding this request.

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| |
|:---|
| Very truly yours, |
| SYNLOGIC, INC. |
| /s/ Mary Beth Dooley |
| Mary Beth Dooley<br> Principal Executive Officer and Principal Financial Officer |

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cc: *<u>Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.</u>*

Daniel A. Bagliebter, Esq.

Nishant Dharia, Esq.