# EDGAR Filing Document

**Accession Number:** 0001773195
**File Stem:** 0001315863-26-000153
**Filing Date:** 2026-2
**Character Count:** 13676
**Document Hash:** 5341fd2f8faa2e4285cb949a9f4a6a3b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001315863-26-000153.hdr.sgml**: 20260213

**ACCESSION NUMBER**: 0001315863-26-000153

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260213

**DATE AS OF CHANGE**: 20260213

**EFFECTIVENESS DATE**: 20260213

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Affinity Asset Advisors, LLC
- **CENTRAL INDEX KEY:** 0001773195

**ORGANIZATION NAME:**
- **EIN:** 821567490
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-20754
- **FILM NUMBER:** 26633878

**BUSINESS ADDRESS:**
- **STREET 1:** 450 PARK AVENUE
- **STREET 2:** SUITE 1403
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022
- **BUSINESS PHONE:** 917-826-4533

**MAIL ADDRESS:**
- **STREET 1:** 450 PARK AVENUE
- **STREET 2:** SUITE 1403
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** Affinity Asset Advisors LLC<br>**Address:** 450 PARK AVENUE<br>SUITE 1403<br>NEW YORK, NY 10022

**Form 13F File Number:** 028-20754

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Andrew Weinstein<br>**Title:** Chief Financial Officer and Chief Compliance Officer<br>**Phone:** 646-481-4455

**Signature, Place, and Date of Signing:**

/s/ Andrew Weinstein  New York, NY  02-13-2026<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 95

**Form 13F Information Table Value Total:** $1755015212

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| ABIVAX SA | SPONSORED ADS | 00370M103 |  | 68101775 | 505000 | SH |  | SOLE |  | 505000 | 0 | 0 |
| ADAGIO MED HLDGS INC | COM | 00534B100 |  | 83200 | 80000 | SH |  | SOLE |  | 80000 | 0 | 0 |
| ALKERMES PLC | SHS | G01767105 |  | 27980000 | 1000000 | SH |  | SOLE |  | 1000000 | 0 | 0 |
| AMGEN INC | COM | 031162100 |  | 3273100 | 10000 | SH |  | SOLE |  | 10000 | 0 | 0 |
| AMGEN INC | COM | 031162100 |  | 44186850 | 135000 | SH | Call | SOLE |  | 135000 | 0 | 0 |
| ANAPTYSBIO INC | COM | 032724106 |  | 21558668 | 444692 | SH |  | SOLE |  | 444692 | 0 | 0 |
| ANTERIS TECHNOLOGIES GLOBAL | COM | 03675P102 |  | 2428553 | 486684 | SH |  | SOLE |  | 486684 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 93212214 | 1234926 | SH |  | SOLE |  | 1234926 | 0 | 0 |
| ARBUTUS BIOPHARMA CORP | COM | 03879J100 |  | 2510339 | 521900 | SH | Call | SOLE |  | 521900 | 0 | 0 |
| ARCELLX INC | COMMON STOCK | 03940C100 |  | 34146870 | 523725 | SH |  | SOLE |  | 523725 | 0 | 0 |
| ARCUS BIOSCIENCES INC | COM | 03969F109 |  | 7149000 | 300000 | SH |  | SOLE |  | 300000 | 0 | 0 |
| ARRIVENT BIOPHARMA INC | COM | 04272N102 |  | 3018000 | 150000 | SH |  | SOLE |  | 150000 | 0 | 0 |
| ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 |  | 4647300 | 70000 | SH |  | SOLE |  | 70000 | 0 | 0 |
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 |  | 6397200 | 30000 | SH |  | SOLE |  | 30000 | 0 | 0 |
| AVADEL PHARMACEUTICALS PLC | COM SHS | G29687103 |  | 5387500 | 250000 | SH |  | SOLE |  | 250000 | 0 | 0 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 |  | 19087141 | 1051054 | SH |  | SOLE |  | 1051054 | 0 | 0 |
| BELITE BIO INC | SPONSORED ADS | 07782B104 |  | 3199200 | 20000 | SH |  | SOLE |  | 20000 | 0 | 0 |
| BRIDGEBIO PHARMA INC | COM | 10806X102 |  | 24476800 | 320000 | SH |  | SOLE |  | 320000 | 0 | 0 |
| CELCUITY INC | NOTE 2.750% 8/0 | 15102KAA8 |  | 6515700 | 3000000 | PRN |  | SOLE |  | 3000000 | 0 | 0 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 |  | 9506000 | 350000 | SH |  | SOLE |  | 350000 | 0 | 0 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 |  | 15019806 | 600552 | SH |  | SOLE |  | 600552 | 0 | 0 |
| CLIMB BIO INC | COM | 28658R106 |  | 5200000 | 1300000 | SH |  | SOLE |  | 1300000 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 12432000 | 350000 | SH |  | SOLE |  | 350000 | 0 | 0 |
| COGENT BIOSCIENCES INC | NOTE 1.625%11/1 | 19240QAA0 |  | 1175800 | 1000000 | PRN |  | SOLE |  | 1000000 | 0 | 0 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 |  | 1380000 | 200000 | SH |  | SOLE |  | 200000 | 0 | 0 |
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 |  | 3491250 | 75000 | SH |  | SOLE |  | 75000 | 0 | 0 |
| CULLINAN THERAPEUTICS INC | COM | 230031106 |  | 19997297 | 1932106 | SH |  | SOLE |  | 1932106 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 50832000 | 800000 | SH |  | SOLE |  | 800000 | 0 | 0 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 |  | 4739150 | 115000 | SH |  | SOLE |  | 115000 | 0 | 0 |
| ENGENE HOLDINGS INC | COM | 29286M105 |  | 5809631 | 643370 | SH |  | SOLE |  | 643370 | 0 | 0 |
| ERASCA INC | COM | 29479A108 |  | 14508000 | 3900000 | SH |  | SOLE |  | 3900000 | 0 | 0 |
| ESTABLISHMENT LABS HLDGS INC | COM | G31249108 |  | 14576000 | 200000 | SH |  | SOLE |  | 200000 | 0 | 0 |
| EUPRAXIA PHARMACEUTICALS INC | COM | 29842P105 |  | 2265000 | 300000 | SH |  | SOLE |  | 300000 | 0 | 0 |
| FORTE BIOSCIENCES INC | COM NEW | 34962G208 |  | 26983392 | 989490 | SH |  | SOLE |  | 989490 | 0 | 0 |
| FORTE BIOSCIENCES INC | COM NEW | 34962G208 |  | 610848 | 22400 | SH | Call | SOLE |  | 22400 | 0 | 0 |
| GERON CORP | COM | 374163103 |  | 1980000 | 1500000 | SH |  | SOLE |  | 1500000 | 0 | 0 |
| IBIO INC | COM NEW | 451033708 |  | 3970396 | 2057200 | SH |  | SOLE |  | 2057200 | 0 | 0 |
| IMMUNOVANT INC | COM | 45258J102 |  | 5084000 | 200000 | SH |  | SOLE |  | 200000 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 78318000 | 450000 | SH |  | SOLE |  | 450000 | 0 | 0 |
| ISHARES TR | ISHARES BIOTECH | 464287556 |  | 67508000 | 400000 | SH | Call | SOLE |  | 400000 | 0 | 0 |
| JADE BIOSCIENCES INC | COM NEW | 008064206 |  | 11031771 | 714956 | SH |  | SOLE |  | 714956 | 0 | 0 |
| KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 |  | 6547272 | 889575 | SH |  | SOLE |  | 889575 | 0 | 0 |
| KEZAR LIFE SCIENCES INC | COM NEW | 49372L209 |  | 1440888 | 229076 | SH |  | SOLE |  | 229076 | 0 | 0 |
| LENZ THERAPEUTICS INC | COM | 52635N103 |  | 1600000 | 100000 | SH | Put | SOLE |  | 100000 | 0 | 0 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 |  | 31776000 | 3200000 | SH |  | SOLE |  | 3200000 | 0 | 0 |
| MACROGENICS INC | COM | 556099109 |  | 779736 | 484308 | SH |  | SOLE |  | 484308 | 0 | 0 |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 |  | 18128827 | 31131 | SH |  | SOLE |  | 31131 | 0 | 0 |
| MBX BIOSCIENCES INC | COM | 55287L101 |  | 7885000 | 250000 | SH |  | SOLE |  | 250000 | 0 | 0 |
| MERSANA THERAPEUTICS INC | COM | 59045L205 |  | 2893000 | 100000 | SH |  | SOLE |  | 100000 | 0 | 0 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 |  | 26491700 | 730000 | SH |  | SOLE |  | 730000 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | *W EXP 99/99/999 | N62509117 |  | 5635000 | 245000 | SH |  | SOLE |  | 245000 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 |  | 9647000 | 275000 | SH |  | SOLE |  | 275000 | 0 | 0 |
| NEXTCURE INC | COM NEW | 65343E207 |  | 3509102 | 247294 | SH |  | SOLE |  | 247294 | 0 | 0 |
| NURIX THERAPEUTICS INC | COM | 67080M103 |  | 18355751 | 967620 | SH |  | SOLE |  | 967620 | 0 | 0 |
| NUVALENT INC | COM | 670703107 |  | 32453653 | 322633 | SH |  | SOLE |  | 322633 | 0 | 0 |
| OAKTREE ACQUISITION CORP III | UNIT 10/04/2029 | G6717R120 |  | 2652500 | 250000 | SH |  | SOLE |  | 250000 | 0 | 0 |
| OMEROS CORP | NOTE 9.500% 6/1 | 682143AK8 |  | 19383995 | 6525000 | PRN |  | SOLE |  | 6525000 | 0 | 0 |
| ORCHESTRA BIOMED HLDGS INC | COM | 68572M106 |  | 2377137 | 572804 | SH |  | SOLE |  | 572804 | 0 | 0 |
| ORUKA THERAPEUTICS INC | COM | 687604108 |  | 24318986 | 802342 | SH |  | SOLE |  | 802342 | 0 | 0 |
| OVID THERAPEUTICS INC | COM | 690469101 |  | 11654500 | 7150000 | SH |  | SOLE |  | 7150000 | 0 | 0 |
| PERCEPTIVE CAP SOLUTIONS COR | CL A ORD SHS | G70077105 |  | 651500 | 50000 | SH |  | SOLE |  | 50000 | 0 | 0 |
| PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 |  | 825000 | 300000 | SH |  | SOLE |  | 300000 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 54526900 | 185000 | SH |  | SOLE |  | 185000 | 0 | 0 |
| PROQR THRAPEUTICS N V | SHS EURO | N71542109 |  | 4957642 | 2454278 | SH |  | SOLE |  | 2454278 | 0 | 0 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 |  | 15033398 | 172125 | SH |  | SOLE |  | 172125 | 0 | 0 |
| Q32 BIO INC | COM | 746964105 |  | 92220 | 27777 | SH |  | SOLE |  | 27777 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 |  | 7965000 | 100000 | SH |  | SOLE |  | 100000 | 0 | 0 |
| REZOLUTE INC | COM NEW | 76200L309 |  | 5548700 | 2351144 | SH |  | SOLE |  | 2351144 | 0 | 0 |
| ROCKET PHARMACEUTICALS INC | *W EXP 09/02/202 | 77313F114 |  | 1823 | 75000 | SH |  | SOLE |  | 75000 | 0 | 0 |
| ROIVANT SCIENCES LTD | SHS | G76279101 |  | 36890000 | 1700000 | SH |  | SOLE |  | 1700000 | 0 | 0 |
| SAGIMET BIOSCIENCES INC | COM SER A | 786700104 |  | 6797610 | 1148245 | SH |  | SOLE |  | 1148245 | 0 | 0 |
| SAVARA INC | COM | 805111101 |  | 16866833 | 2797153 | SH |  | SOLE |  | 2797153 | 0 | 0 |
| SELECT SECTOR SPDR TR | STATE STREET HEA | 81369Y209 |  | 38700000 | 250000 | SH | Call | SOLE |  | 250000 | 0 | 0 |
| SPDR SERIES TRUST | STATE STREET SPD | 78464A870 |  | 182895000 | 1500000 | SH | Put | SOLE |  | 1500000 | 0 | 0 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 |  | 46931681 | 1432591 | SH |  | SOLE |  | 1432591 | 0 | 0 |
| SUMMIT THERAPEUTICS INC | COM | 86627T108 |  | 6121500 | 350000 | SH | Put | SOLE |  | 350000 | 0 | 0 |
| SUTRO BIOPHARMA INC | COM SHS | 869367201 |  | 8658780 | 748382 | SH |  | SOLE |  | 748382 | 0 | 0 |
| TANGO THERAPEUTICS INC | COM | 87583X109 |  | 8860000 | 1000000 | SH |  | SOLE |  | 1000000 | 0 | 0 |
| TAYSHA GENE THERAPIES INC | COM SHS | 877619106 |  | 18150000 | 3300000 | SH |  | SOLE |  | 3300000 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 22220000 | 550000 | SH |  | SOLE |  | 550000 | 0 | 0 |
| TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | 881624209 |  | 43694000 | 1400000 | SH |  | SOLE |  | 1400000 | 0 | 0 |
| TRAVERE THERAPEUTICS INC | COM | 89422G107 |  | 11463000 | 300000 | SH |  | SOLE |  | 300000 | 0 | 0 |
| TRAVERE THERAPEUTICS INC | NOTE 2.250% 3/0 | 89422GAA5 |  | 9989000 | 7000000 | PRN |  | SOLE |  | 7000000 | 0 | 0 |
| TREVI THERAPEUTICS INC | COM | 89532M101 |  | 26920153 | 2150172 | SH |  | SOLE |  | 2150172 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 1725000 | 75000 | SH |  | SOLE |  | 75000 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 |  | 1196500 | 50000 | SH |  | SOLE |  | 50000 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 |  | 19144000 | 800000 | SH | Call | SOLE |  | 800000 | 0 | 0 |
| VENTYX BIOSCIENCES INC | COM | 92332V107 |  | 58555559 | 6484558 | SH |  | SOLE |  | 6484558 | 0 | 0 |
| VERA THERAPEUTICS INC | CL A | 92337R101 |  | 12660000 | 250000 | SH |  | SOLE |  | 250000 | 0 | 0 |
| VERRICA PHARMACEUTICALS INC | COM SHS | 92511W207 |  | 5877979 | 707338 | SH |  | SOLE |  | 707338 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 |  | 7780000 | 250000 | SH |  | SOLE |  | 250000 | 0 | 0 |
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 |  | 45900000 | 2700000 | SH |  | SOLE |  | 2700000 | 0 | 0 |
| X4 PHARMACEUTICALS INC | COM NEW | 98420X202 |  | 580000 | 145000 | SH |  | SOLE |  | 145000 | 0 | 0 |
| XENON PHARMACEUTICALS INC | COM | 98420N105 |  | 56025000 | 1250000 | SH |  | SOLE |  | 1250000 | 0 | 0 |
| ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 |  | 9503636 | 1813671 | SH |  | SOLE |  | 1813671 | 0 | 0 |

---