# EDGAR Filing Document

**Accession Number:** 0001521036
**File Stem:** 0000899243-23-007259
**Filing Date:** 2023-3
**Character Count:** 9214
**Document Hash:** e6922a6e0e2e8af92d8131a56fb36c4d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000899243-23-007259.hdr.sgml**: 20230306

**ACCESSION NUMBER**: 0000899243-23-007259

**CONFORMED SUBMISSION TYPE**: 4

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20230302

**FILED AS OF DATE**: 20230306

**DATE AS OF CHANGE**: 20230306

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Heino Mary Anne
- **CENTRAL INDEX KEY:** 0001610676

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-36569
- **FILM NUMBER:** 23710863

**MAIL ADDRESS:**
- **STREET 1:** C/O LANTHEUS HOLDINGS, INC.
- **STREET 2:** 331 TREBLE COVE ROAD
- **CITY:** NORTH BILLERICA
- **STATE:** NY
- **ZIP:** 01862
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Lantheus Holdings, Inc.
- **CENTRAL INDEX KEY:** 0001521036
- **STANDARD INDUSTRIAL CLASSIFICATION:** IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
- **IRS NUMBER:** 352318913
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 331 TREBLE COVE ROAD
- **CITY:** NORTH BILLERICA
- **STATE:** MA
- **ZIP:** 01862
- **BUSINESS PHONE:** 978 671-8001

**MAIL ADDRESS:**
- **STREET 1:** 331 TREBLE COVE ROAD
- **CITY:** NORTH BILLERICA
- **STATE:** MA
- **ZIP:** 01862

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Lantheus MI Holdings, Inc.
- **DATE OF NAME CHANGE:** 20110517

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 4

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[ ] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Heino Mary Anne<br><sub>(Last) (First) (Middle)</sub><br>C/O LANTHEUS HOLDINGS, INC.<br>201 BURLINGTON ROAD, SOUTH BLDG<br><sub>(Street)</sub><br>BEDFORD, MA 01730<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2023-03-02 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [ ] 10% Owner<br>[X] Officer (give title below) [ ] Other (specify below)<br>_President & CEO_ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>Lantheus Holdings, Inc. [ LNTH ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[X] Form filed by One Reporting Person<br>[ ] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Common Stock | 2023-03-02 |  | A<sup>(1)</sup> |  | 76686 | A | $0.00 | 749219 | D |  |
| Common Stock | 2023-03-03 |  | A<sup>(2)</sup> |  | 74486 | A | $0.00 | 823705 | D |  |
| Common Stock | 2023-03-03 |  | S<sup>(3)</sup> |  | 64658 | D | 72.8996<sup>(4)</sup> | 759047 | D |  |
| Common Stock | 2023-03-03 |  | S<sup>(3)</sup> |  | 17397 | D | 73.3524<sup>(5)</sup> | 741650 | D |  |
| Common Stock | 2023-03-06 |  | S<sup>(3)</sup> |  | 12189 | D | 73.244<sup>(6)</sup> | 729461 | D |  |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| Stock Option (right to buy) | $73.35 | 2023-03-02 |  | A |  | 44696 |  | <sup>(7)</sup> | 2033-03-02 | Common Stock | 44696 | $0.00 | 44696 | D |  |

---

### Footnotes:

(1) Consists of 25,562 restricted stock units that vest in equal installments over a three-year period and 51,124 Total Shareholder Return performance-based restricted stock units ("PSUs") that cliff vest following a three-year performance period. The amount of PSUs included in this Report reflects the target award, however the ultimate award size can range from 0% to 200% of the target based on the actual performance achieved at the end of the performance period.

(2) The transaction reported in this Form 4 reflects additional shares of common stock issued by the Company to the reporting person upon the vesting of relative Total Shareholder Return PSUs that were previously granted and included in the Form 4 filed on March 5, 2020. The number of shares reported in the Form 4 reflected 100% of the target number of shares underlying the PSUs. The number of shares that actually vested under the PSUs equaled 200% of the target number of shares. Accordingly, the number of shares reported in this Form 4 reflects the difference between the number of shares that actually vested under the PSUs and the target number of shares originally included in the Form 4.

(3) The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

(4) The price reported in Column 4 is a weighted average price.  These shares were sold in multiple transactions at prices ranging from $72.14 to $73.135, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc. ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

(5) The price reported in Column 4 is a weighted average price.  These shares were sold in multiple transactions at prices ranging from $73.14 to $73.99, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (5) to this Form 4.

(6) The price reported in Column 4 is a weighted average price.  These shares were sold in multiple transactions at prices ranging from $71.69 to $72.6, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (6) to this Form 4.

(7) The option vests in three equal annual installments beginning on March 2, 2024.

**Signature:** /s/  Eric M. Green, attorney-in-fact  
**Date:** 2023-03-06

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**