# EDGAR Filing Document

**Accession Number:** 0000052848
**File Stem:** 0000052848-26-000153
**Filing Date:** 2026-1
**Character Count:** 214454
**Document Hash:** 66429badcea73a0afc3e88727242bc6b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000052848-26-000153.hdr.sgml**: 20260128

**ACCESSION NUMBER**: 0000052848-26-000153

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20251130

**FILED AS OF DATE**: 20260128

**DATE AS OF CHANGE**: 20260127

**PERIOD START**: 20260831

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** VANGUARD WORLD FUND
- **CENTRAL INDEX KEY:** 0000052848

**ORGANIZATION NAME:**
- **EIN:** 046035483
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0831

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-01027
- **FILM NUMBER:** 26567983

**BUSINESS ADDRESS:**
- **STREET 1:** PO BOX 2600
- **STREET 2:** V26
- **CITY:** VALLEY FORGE
- **STATE:** PA
- **ZIP:** 19482
- **BUSINESS PHONE:** 6106691000

**MAIL ADDRESS:**
- **STREET 1:** PO BOX 2600
- **STREET 2:** V26
- **CITY:** VALLEY FORGE
- **STATE:** PA
- **ZIP:** 19482

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VANGUARD WORLD FUNDS
- **DATE OF NAME CHANGE:** 20020402

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VANGUARD WORLD FUND INC
- **DATE OF NAME CHANGE:** 19920703

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** IVEST FUND INC
- **DATE OF NAME CHANGE:** 19850923

## Series and Classes Contracts Data

### Vanguard Health Care Index Fund (Series ID: S000004450)

| Class ID   | Class Name     | Ticker Symbol   |
|:---|:---|:---|
| C000012222 | Admiral Shares | VHCIX           |
| C000012223 | ETF Shares     | VHT             |

## Nport-Ex

Vanguard<sup>®</sup> Health Care Index Fund

#### Schedule of Investments (unaudited)
As of November 30, 2025

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund's Form N-PORT reports are available on the SEC's website at www.sec.gov.

---

| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
| **Common Stocks (95.9%)** | **Common Stocks (95.9%)** | **Common Stocks (95.9%)** | **Common Stocks (95.9%)** |
| **Biotechnology (21.2%)** | **Biotechnology (21.2%)** | **Biotechnology (21.2%)** | **Biotechnology (21.2%)** |
|  | &nbsp;&nbsp;&nbsp;AbbVie Inc. | 4508767 | &nbsp;&nbsp;&nbsp;&nbsp; 1026646 |
|  | &nbsp;&nbsp;&nbsp;Amgen Inc. | 1633110 | &nbsp;&nbsp;&nbsp;&nbsp; 564174 |
|  | &nbsp;&nbsp;&nbsp;Gilead Sciences Inc. | 3763946 | &nbsp;&nbsp;&nbsp;&nbsp; 473655 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Vertex Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;777759 | &nbsp;&nbsp;&nbsp;&nbsp; 337244 |
|  | &nbsp;&nbsp;&nbsp;Regeneron Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;316007 | &nbsp;&nbsp;&nbsp;&nbsp; 246546 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Alnylam Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;397629 | &nbsp;&nbsp;&nbsp;&nbsp; 179422 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Insmed Inc. | &nbsp;&nbsp;&nbsp;&nbsp;641218 | &nbsp;&nbsp;&nbsp;&nbsp; 133226 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Natera Inc. | &nbsp;&nbsp;&nbsp;&nbsp;395548 | &nbsp;&nbsp;&nbsp;&nbsp; 94461 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Biogen Inc. | &nbsp;&nbsp;&nbsp;&nbsp;444816 | &nbsp;&nbsp;&nbsp;&nbsp; 80997 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;United Therapeutics Corp. | &nbsp;&nbsp;&nbsp;&nbsp;130343 | &nbsp;&nbsp;&nbsp;&nbsp; 63347 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Exact Sciences Corp. | &nbsp;&nbsp;&nbsp;&nbsp;574332 | &nbsp;&nbsp;&nbsp;&nbsp; 58174 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Incyte Corp. | &nbsp;&nbsp;&nbsp;&nbsp;503545 | &nbsp;&nbsp;&nbsp;&nbsp; 52600 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Neurocrine Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;300966 | &nbsp;&nbsp;&nbsp;&nbsp; 45795 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ionis Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;459198 | &nbsp;&nbsp;&nbsp;&nbsp; 37989 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Exelixis Inc. | &nbsp;&nbsp;&nbsp;&nbsp;776311 | &nbsp;&nbsp;&nbsp;&nbsp; 34290 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Revolution Medicines Inc. | &nbsp;&nbsp;&nbsp;&nbsp;425622 | &nbsp;&nbsp;&nbsp;&nbsp; 33096 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Bridgebio Pharma Inc. | &nbsp;&nbsp;&nbsp;&nbsp;435279 | &nbsp;&nbsp;&nbsp;&nbsp; 31344 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;BioMarin Pharmaceutical Inc. | &nbsp;&nbsp;&nbsp;&nbsp;552938 | &nbsp;&nbsp;&nbsp;&nbsp; 30926 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Moderna Inc. | 1065425 | &nbsp;&nbsp;&nbsp;&nbsp; 27680 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Madrigal Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;43996 | &nbsp;&nbsp;&nbsp;&nbsp; 26265 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Halozyme Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;355215 | &nbsp;&nbsp;&nbsp;&nbsp; 25362 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Avidity Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;331657 | &nbsp;&nbsp;&nbsp;&nbsp; 23780 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Roivant Sciences Ltd. | 1140582 | &nbsp;&nbsp;&nbsp;&nbsp; 23736 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cytokinetics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;344701 | &nbsp;&nbsp;&nbsp;&nbsp; 23484 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arrowhead Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;377069 | &nbsp;&nbsp;&nbsp;&nbsp; 19872 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Rhythm Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;171104 | &nbsp;&nbsp;&nbsp;&nbsp; 18666 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;PTC Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;216965 | &nbsp;&nbsp;&nbsp;&nbsp; 18657 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Vaxcyte Inc. | &nbsp;&nbsp;&nbsp;&nbsp;354127 | &nbsp;&nbsp;&nbsp;&nbsp; 17568 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Merus NV | &nbsp;&nbsp;&nbsp;&nbsp;172262 | &nbsp;&nbsp;&nbsp;&nbsp; 16561 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;TG Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;457312 | &nbsp;&nbsp;&nbsp;&nbsp; 15210 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Krystal Biotech Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;65867 | &nbsp;&nbsp;&nbsp;&nbsp; 14359 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Alkermes plc | &nbsp;&nbsp;&nbsp;&nbsp;475026 | &nbsp;&nbsp;&nbsp;&nbsp; 14051 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ADMA Biologics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;723735 | &nbsp;&nbsp;&nbsp;&nbsp; 13881 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Protagonist Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;150888 | &nbsp;&nbsp;&nbsp;&nbsp; 13580 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Nuvalent Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;121242 | &nbsp;&nbsp;&nbsp;&nbsp; 13258 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;GRAIL Inc. | &nbsp;&nbsp;&nbsp;&nbsp;111276 | &nbsp;&nbsp;&nbsp;&nbsp; 12284 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Praxis Precision Medicines Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;62383 | &nbsp;&nbsp;&nbsp;&nbsp; 12256 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Viking Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;324740 | &nbsp;&nbsp;&nbsp;&nbsp; 11954 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Veracyte Inc. | &nbsp;&nbsp;&nbsp;&nbsp;239036 | &nbsp;&nbsp;&nbsp;&nbsp; 11316 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cogent Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;254664 | &nbsp;&nbsp;&nbsp;&nbsp; 10243 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arcutis Biotherapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;327611 | &nbsp;&nbsp;&nbsp;&nbsp; 10041 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ultragenyx Pharmaceutical Inc. | &nbsp;&nbsp;&nbsp;&nbsp;262894 | &nbsp;&nbsp;&nbsp;&nbsp; 9136 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Travere Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;256769 | &nbsp;&nbsp;&nbsp;&nbsp; 9092 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ACADIA Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;357890 | &nbsp;&nbsp;&nbsp;&nbsp; 8962 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Akero Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;157952 | &nbsp;&nbsp;&nbsp;&nbsp; 8586 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ideaya Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;239783 | &nbsp;&nbsp;&nbsp;&nbsp; 8541 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Amicus Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;840541 | &nbsp;&nbsp;&nbsp;&nbsp; 8347 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Scholar Rock Holding Corp. | &nbsp;&nbsp;&nbsp;&nbsp;189368 | &nbsp;&nbsp;&nbsp;&nbsp; 8344 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Mirum Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;114189 | &nbsp;&nbsp;&nbsp;&nbsp; 8342 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Catalyst Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;353301 | &nbsp;&nbsp;&nbsp;&nbsp; 8271 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Denali Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;420979 | &nbsp;&nbsp;&nbsp;&nbsp; 8196 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Kymera Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;119570 | &nbsp;&nbsp;&nbsp;&nbsp; 8116 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Summit Therapeutics Inc. (XNMS) | &nbsp;&nbsp;&nbsp;&nbsp;449873 | &nbsp;&nbsp;&nbsp;&nbsp; 8048 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cidara Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;34535 | &nbsp;&nbsp;&nbsp;&nbsp; 7594 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Beam Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;276385 | &nbsp;&nbsp;&nbsp;&nbsp; 7001 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Apogee Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;96594 | &nbsp;&nbsp;&nbsp;&nbsp; 6952 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Soleno Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;136877 | &nbsp;&nbsp;&nbsp;&nbsp; 6905 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Disc Medicine Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;73750 | &nbsp;&nbsp;&nbsp;&nbsp; 6885 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arcus Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;258321 | &nbsp;&nbsp;&nbsp;&nbsp; 6742 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Sarepta Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;301301 | &nbsp;&nbsp;&nbsp;&nbsp; 6430 |

---

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| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Viridian Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;197489 | &nbsp;&nbsp;&nbsp;&nbsp; 6312 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Vericel Corp. | &nbsp;&nbsp;&nbsp;&nbsp;153012 | &nbsp;&nbsp;&nbsp;&nbsp; 6159 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Dyne Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;280245 | &nbsp;&nbsp;&nbsp;&nbsp; 6137 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arcellx Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;83829 | &nbsp;&nbsp;&nbsp;&nbsp; 6095 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Mineralys Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;139121 | &nbsp;&nbsp;&nbsp;&nbsp; 5999 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Twist Bioscience Corp. | &nbsp;&nbsp;&nbsp;&nbsp;183722 | &nbsp;&nbsp;&nbsp;&nbsp; 5881 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;CG oncology Inc. | &nbsp;&nbsp;&nbsp;&nbsp;129626 | &nbsp;&nbsp;&nbsp;&nbsp; 5812 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Newamsterdam Pharma Co. NV | &nbsp;&nbsp;&nbsp;&nbsp;136841 | &nbsp;&nbsp;&nbsp;&nbsp; 5652 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Aurinia Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;339041 | &nbsp;&nbsp;&nbsp;&nbsp; 5465 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Recursion Pharmaceuticals Inc. Class A | 1106744 | &nbsp;&nbsp;&nbsp;&nbsp; 5124 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Immunovant Inc. | &nbsp;&nbsp;&nbsp;&nbsp;211318 | &nbsp;&nbsp;&nbsp;&nbsp; 5103 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Syndax Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;248940 | &nbsp;&nbsp;&nbsp;&nbsp; 4934 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Agios Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;168212 | &nbsp;&nbsp;&nbsp;&nbsp; 4912 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Apellis Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;230182 | &nbsp;&nbsp;&nbsp;&nbsp; 4903 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Celldex Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;181153 | &nbsp;&nbsp;&nbsp;&nbsp; 4895 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MannKind Corp. | &nbsp;&nbsp;&nbsp;&nbsp;883201 | &nbsp;&nbsp;&nbsp;&nbsp; 4725 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Kiniksa Pharmaceuticals International plc | &nbsp;&nbsp;&nbsp;&nbsp;105373 | &nbsp;&nbsp;&nbsp;&nbsp; 4480 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Spyre Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;148352 | &nbsp;&nbsp;&nbsp;&nbsp; 4451 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;BioCryst Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;604209 | &nbsp;&nbsp;&nbsp;&nbsp; 4338 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ardelyx Inc. | &nbsp;&nbsp;&nbsp;&nbsp;732805 | &nbsp;&nbsp;&nbsp;&nbsp; 4250 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Nurix Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;229617 | &nbsp;&nbsp;&nbsp;&nbsp; 4060 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Janux Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;118946 | &nbsp;&nbsp;&nbsp;&nbsp; 4055 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Vera Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;116066 | &nbsp;&nbsp;&nbsp;&nbsp; 3917 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Immunome Inc. | &nbsp;&nbsp;&nbsp;&nbsp;212500 | &nbsp;&nbsp;&nbsp;&nbsp; 3914 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Celcuity Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;38518 | &nbsp;&nbsp;&nbsp;&nbsp; 3896 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Stoke Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;116492 | &nbsp;&nbsp;&nbsp;&nbsp; 3601 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Biohaven Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;352464 | &nbsp;&nbsp;&nbsp;&nbsp; 3535 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;UroGen Pharma Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;119003 | &nbsp;&nbsp;&nbsp;&nbsp; 3428 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Olema Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;114394 | &nbsp;&nbsp;&nbsp;&nbsp; 3240 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Dynavax Technologies Corp. | &nbsp;&nbsp;&nbsp;&nbsp;284205 | &nbsp;&nbsp;&nbsp;&nbsp; 3231 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Xencor Inc. | &nbsp;&nbsp;&nbsp;&nbsp;182908 | &nbsp;&nbsp;&nbsp;&nbsp; 3168 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Zymeworks Inc. | &nbsp;&nbsp;&nbsp;&nbsp;113571 | &nbsp;&nbsp;&nbsp;&nbsp; 3034 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Novavax Inc. | &nbsp;&nbsp;&nbsp;&nbsp;418287 | &nbsp;&nbsp;&nbsp;&nbsp; 2949 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Relay Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;369446 | &nbsp;&nbsp;&nbsp;&nbsp; 2926 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Intellia Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;309034 | &nbsp;&nbsp;&nbsp;&nbsp; 2778 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;CareDx Inc. | &nbsp;&nbsp;&nbsp;&nbsp;153178 | &nbsp;&nbsp;&nbsp;&nbsp; 2737 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Kura Oncology Inc. | &nbsp;&nbsp;&nbsp;&nbsp;223510 | &nbsp;&nbsp;&nbsp;&nbsp; 2713 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MiMedx Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;360163 | &nbsp;&nbsp;&nbsp;&nbsp; 2478 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;ImmunityBio Inc. | 1002462 | &nbsp;&nbsp;&nbsp;&nbsp; 2366 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Iovance Biotherapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;931826 | &nbsp;&nbsp;&nbsp;&nbsp; 2302 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Palvella Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;21747 | &nbsp;&nbsp;&nbsp;&nbsp; 2235 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Sana Biotechnology Inc. | &nbsp;&nbsp;&nbsp;&nbsp;515977 | &nbsp;&nbsp;&nbsp;&nbsp; 2219 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Rezolute Inc. | &nbsp;&nbsp;&nbsp;&nbsp;219860 | &nbsp;&nbsp;&nbsp;&nbsp; 2137 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Myriad Genetics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;279216 | &nbsp;&nbsp;&nbsp;&nbsp; 2130 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Dianthus Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;48227 | &nbsp;&nbsp;&nbsp;&nbsp; 2121 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Day One Biopharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;217208 | &nbsp;&nbsp;&nbsp;&nbsp; 2061 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Precigen Inc. | &nbsp;&nbsp;&nbsp;&nbsp;535730 | &nbsp;&nbsp;&nbsp;&nbsp; 2052 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Kodiak Sciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;87910 | &nbsp;&nbsp;&nbsp;&nbsp; 2020 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Oruka Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;65873 | &nbsp;&nbsp;&nbsp;&nbsp; 1983 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Taysha Gene Therapies Inc. | &nbsp;&nbsp;&nbsp;&nbsp;413475 | &nbsp;&nbsp;&nbsp;&nbsp; 1960 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arbutus Biopharma Corp. | &nbsp;&nbsp;&nbsp;&nbsp;435352 | &nbsp;&nbsp;&nbsp;&nbsp; 1920 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Zenas Biopharma Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;48489 | &nbsp;&nbsp;&nbsp;&nbsp; 1883 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Gossamer Bio Inc. | &nbsp;&nbsp;&nbsp;&nbsp;550397 | &nbsp;&nbsp;&nbsp;&nbsp; 1838 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Emergent BioSolutions Inc. | &nbsp;&nbsp;&nbsp;&nbsp;160696 | &nbsp;&nbsp;&nbsp;&nbsp; 1795 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;AnaptysBio Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;42429 | &nbsp;&nbsp;&nbsp;&nbsp; 1767 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Vir Biotechnology Inc. | &nbsp;&nbsp;&nbsp;&nbsp;272758 | &nbsp;&nbsp;&nbsp;&nbsp; 1751 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;REGENXBIO Inc. | &nbsp;&nbsp;&nbsp;&nbsp;128790 | &nbsp;&nbsp;&nbsp;&nbsp; 1725 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Geron Corp. (XNGS) | 1454632 | &nbsp;&nbsp;&nbsp;&nbsp; 1716 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Erasca Inc. | &nbsp;&nbsp;&nbsp;&nbsp;522357 | &nbsp;&nbsp;&nbsp;&nbsp; 1656 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Annexon Inc. | &nbsp;&nbsp;&nbsp;&nbsp;361123 | &nbsp;&nbsp;&nbsp;&nbsp; 1625 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;CytomX Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;374202 | &nbsp;&nbsp;&nbsp;&nbsp; 1602 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ORIC Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;132390 | &nbsp;&nbsp;&nbsp;&nbsp; 1573 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ARS Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;164539 | &nbsp;&nbsp;&nbsp;&nbsp; 1570 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Corvus Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;169010 | &nbsp;&nbsp;&nbsp;&nbsp; 1550 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ironwood Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;442766 | &nbsp;&nbsp;&nbsp;&nbsp; 1550 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Monte Rosa Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;94017 | &nbsp;&nbsp;&nbsp;&nbsp; 1520 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tango Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;137651 | &nbsp;&nbsp;&nbsp;&nbsp; 1502 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Prothena Corp. plc | &nbsp;&nbsp;&nbsp;&nbsp;138660 | &nbsp;&nbsp;&nbsp;&nbsp; 1491 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Replimune Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;141875 | &nbsp;&nbsp;&nbsp;&nbsp; 1419 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ArriVent Biopharma Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;61426 | &nbsp;&nbsp;&nbsp;&nbsp; 1409 |

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| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Altimmune Inc. | &nbsp;&nbsp;&nbsp;&nbsp;267371 | &nbsp;&nbsp;&nbsp;&nbsp; 1406 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Verastem Inc. | &nbsp;&nbsp;&nbsp;&nbsp;130356 | &nbsp;&nbsp;&nbsp;&nbsp; 1387 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MoonLake Immunotherapeutics | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;96389 | &nbsp;&nbsp;&nbsp;&nbsp; 1323 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Savara Inc. | &nbsp;&nbsp;&nbsp;&nbsp;209432 | &nbsp;&nbsp;&nbsp;&nbsp; 1317 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;4D Molecular Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;106111 | &nbsp;&nbsp;&nbsp;&nbsp; 1237 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;KalVista Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;84188 | &nbsp;&nbsp;&nbsp;&nbsp; 1218 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Akebia Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;763213 | &nbsp;&nbsp;&nbsp;&nbsp; 1206 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Astria Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;94021 | &nbsp;&nbsp;&nbsp;&nbsp; 1189 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Ocugen Inc. | &nbsp;&nbsp;&nbsp;&nbsp;946035 | &nbsp;&nbsp;&nbsp;&nbsp; 1173 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Upstream Bio Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;40769 | &nbsp;&nbsp;&nbsp;&nbsp; 1166 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MeiraGTx Holdings plc | &nbsp;&nbsp;&nbsp;&nbsp;132428 | &nbsp;&nbsp;&nbsp;&nbsp; 1099 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cullinan Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;89440 | &nbsp;&nbsp;&nbsp;&nbsp; 1017 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Prime Medicine Inc. | &nbsp;&nbsp;&nbsp;&nbsp;261322 | &nbsp;&nbsp;&nbsp;&nbsp; 998 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Organogenesis Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;192052 | &nbsp;&nbsp;&nbsp;&nbsp; 995 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Anavex Life Sciences Corp. | &nbsp;&nbsp;&nbsp;&nbsp;257809 | &nbsp;&nbsp;&nbsp;&nbsp; 987 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;XOMA Royalty Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;29220 | &nbsp;&nbsp;&nbsp;&nbsp; 939 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Bicara Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;49636 | &nbsp;&nbsp;&nbsp;&nbsp; 921 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tyra Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;40565 | &nbsp;&nbsp;&nbsp;&nbsp; 915 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Keros Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;52251 | &nbsp;&nbsp;&nbsp;&nbsp; 913 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Vanda Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;169746 | &nbsp;&nbsp;&nbsp;&nbsp; 910 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Aura Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;131710 | &nbsp;&nbsp;&nbsp;&nbsp; 869 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Aldeyra Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;156963 | &nbsp;&nbsp;&nbsp;&nbsp; 860 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Rocket Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;246053 | &nbsp;&nbsp;&nbsp;&nbsp; 842 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Allogene Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;488023 | &nbsp;&nbsp;&nbsp;&nbsp; 713 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Editas Medicine Inc. | &nbsp;&nbsp;&nbsp;&nbsp;272278 | &nbsp;&nbsp;&nbsp;&nbsp; 656 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Humacyte Inc. | &nbsp;&nbsp;&nbsp;&nbsp;482014 | &nbsp;&nbsp;&nbsp;&nbsp; 651 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Entrada Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;58018 | &nbsp;&nbsp;&nbsp;&nbsp; 596 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Lyell Immunopharma Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;23255 | &nbsp;&nbsp;&nbsp;&nbsp; 558 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arcturus Therapeutics Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;74388 | &nbsp;&nbsp;&nbsp;&nbsp; 505 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Heron Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;421833 | &nbsp;&nbsp;&nbsp;&nbsp; 489 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Perspective Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;193347 | &nbsp;&nbsp;&nbsp;&nbsp; 454 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Fate Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;297159 | &nbsp;&nbsp;&nbsp;&nbsp; 339 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Alector Inc. | &nbsp;&nbsp;&nbsp;&nbsp;243064 | &nbsp;&nbsp;&nbsp;&nbsp; 323 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MacroGenics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;155988 | &nbsp;&nbsp;&nbsp;&nbsp; 239 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Zentalis Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;137107 | &nbsp;&nbsp;&nbsp;&nbsp; 196 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ALX Oncology Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;77337 | &nbsp;&nbsp;&nbsp;&nbsp; 106 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Applied Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;326454 | &nbsp;&nbsp;&nbsp;&nbsp; 85 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Korro Bio Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;13898 | &nbsp;&nbsp;&nbsp;&nbsp; 79 |
| <sup>\*,2</sup> | &nbsp;&nbsp;&nbsp;Prevail Therapeutics CVR | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;78 | &nbsp;&nbsp;&nbsp;&nbsp; — |
| <sup>\*,2</sup> | &nbsp;&nbsp;&nbsp;89bio Inc. CVR | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;240 | &nbsp;&nbsp;&nbsp;&nbsp; — |
|  |  |  | &nbsp;&nbsp;&nbsp;&nbsp; **4323097** |
| **Health Care Equipment & Supplies (20.2%)** | **Health Care Equipment & Supplies (20.2%)** | **Health Care Equipment & Supplies (20.2%)** | **Health Care Equipment & Supplies (20.2%)** |
|  | &nbsp;&nbsp;&nbsp;Abbott Laboratories | 5279589 | &nbsp;&nbsp;&nbsp;&nbsp; 680539 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Intuitive Surgical Inc. | 1087443 | &nbsp;&nbsp;&nbsp;&nbsp; 623627 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Boston Scientific Corp. | 4494892 | &nbsp;&nbsp;&nbsp;&nbsp; 456591 |
|  | &nbsp;&nbsp;&nbsp;Medtronic plc | 3891014 | &nbsp;&nbsp;&nbsp;&nbsp; 409840 |
|  | &nbsp;&nbsp;&nbsp;Stryker Corp. | 1043763 | &nbsp;&nbsp;&nbsp;&nbsp; 387424 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;IDEXX Laboratories Inc. | &nbsp;&nbsp;&nbsp;&nbsp;242693 | &nbsp;&nbsp;&nbsp;&nbsp; 182719 |
|  | &nbsp;&nbsp;&nbsp;Becton Dickinson & Co. | &nbsp;&nbsp;&nbsp;&nbsp;869574 | &nbsp;&nbsp;&nbsp;&nbsp; 168715 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Edwards Lifesciences Corp. | 1780978 | &nbsp;&nbsp;&nbsp;&nbsp; 154357 |
|  | &nbsp;&nbsp;&nbsp;ResMed Inc. | &nbsp;&nbsp;&nbsp;&nbsp;442315 | &nbsp;&nbsp;&nbsp;&nbsp; 113157 |
|  | &nbsp;&nbsp;&nbsp;GE HealthCare Technologies Inc. | 1385178 | &nbsp;&nbsp;&nbsp;&nbsp; 110800 |
|  | &nbsp;&nbsp;&nbsp;STERIS plc | &nbsp;&nbsp;&nbsp;&nbsp;298798 | &nbsp;&nbsp;&nbsp;&nbsp; 79564 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Dexcom Inc. | 1189728 | &nbsp;&nbsp;&nbsp;&nbsp; 75512 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Insulet Corp. | &nbsp;&nbsp;&nbsp;&nbsp;213554 | &nbsp;&nbsp;&nbsp;&nbsp; 69873 |
|  | &nbsp;&nbsp;&nbsp;Zimmer Biomet Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;601059 | &nbsp;&nbsp;&nbsp;&nbsp; 58615 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Hologic Inc. | &nbsp;&nbsp;&nbsp;&nbsp;674762 | &nbsp;&nbsp;&nbsp;&nbsp; 50587 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cooper Cos. Inc. | &nbsp;&nbsp;&nbsp;&nbsp;602508 | &nbsp;&nbsp;&nbsp;&nbsp; 46953 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Solventum Corp. | &nbsp;&nbsp;&nbsp;&nbsp;472437 | &nbsp;&nbsp;&nbsp;&nbsp; 40280 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Penumbra Inc. | &nbsp;&nbsp;&nbsp;&nbsp;112444 | &nbsp;&nbsp;&nbsp;&nbsp; 32965 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Align Technology Inc. | &nbsp;&nbsp;&nbsp;&nbsp;208796 | &nbsp;&nbsp;&nbsp;&nbsp; 30733 |
|  | &nbsp;&nbsp;&nbsp;Baxter International Inc. | 1559063 | &nbsp;&nbsp;&nbsp;&nbsp; 29217 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Globus Medical Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;241858 | &nbsp;&nbsp;&nbsp;&nbsp; 22019 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Masimo Corp. | &nbsp;&nbsp;&nbsp;&nbsp;140076 | &nbsp;&nbsp;&nbsp;&nbsp; 19951 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Glaukos Corp. | &nbsp;&nbsp;&nbsp;&nbsp;173798 | &nbsp;&nbsp;&nbsp;&nbsp; 18473 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;iRhythm Technologies Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;97364 | &nbsp;&nbsp;&nbsp;&nbsp; 18305 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Merit Medical Systems Inc. | &nbsp;&nbsp;&nbsp;&nbsp;179664 | &nbsp;&nbsp;&nbsp;&nbsp; 15557 |
|  | &nbsp;&nbsp;&nbsp;Teleflex Inc. | &nbsp;&nbsp;&nbsp;&nbsp;134016 | &nbsp;&nbsp;&nbsp;&nbsp; 15334 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;TransMedics Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;98142 | &nbsp;&nbsp;&nbsp;&nbsp; 14359 |

---

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| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Lantheus Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;206033 | &nbsp;&nbsp;&nbsp;&nbsp; 12129 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Haemonetics Corp. | &nbsp;&nbsp;&nbsp;&nbsp;146023 | &nbsp;&nbsp;&nbsp;&nbsp; 11879 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Inspire Medical Systems Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;85303 | &nbsp;&nbsp;&nbsp;&nbsp; 10613 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;LivaNova plc | &nbsp;&nbsp;&nbsp;&nbsp;165819 | &nbsp;&nbsp;&nbsp;&nbsp; 10581 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ICU Medical Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;71096 | &nbsp;&nbsp;&nbsp;&nbsp; 10553 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Envista Holdings Corp. | &nbsp;&nbsp;&nbsp;&nbsp;503483 | &nbsp;&nbsp;&nbsp;&nbsp; 10523 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Alphatec Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;358732 | &nbsp;&nbsp;&nbsp;&nbsp; 8089 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Integer Holdings Corp. | &nbsp;&nbsp;&nbsp;&nbsp;106514 | &nbsp;&nbsp;&nbsp;&nbsp; 7688 |
|  | &nbsp;&nbsp;&nbsp;DENTSPLY SIRONA Inc. | &nbsp;&nbsp;&nbsp;&nbsp;605737 | &nbsp;&nbsp;&nbsp;&nbsp; 6869 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Artivion Inc. | &nbsp;&nbsp;&nbsp;&nbsp;121448 | &nbsp;&nbsp;&nbsp;&nbsp; 5667 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;QuidelOrtho Corp. | &nbsp;&nbsp;&nbsp;&nbsp;206558 | &nbsp;&nbsp;&nbsp;&nbsp; 5649 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;AtriCure Inc. | &nbsp;&nbsp;&nbsp;&nbsp;151211 | &nbsp;&nbsp;&nbsp;&nbsp; 5462 |
|  | &nbsp;&nbsp;&nbsp;LeMaitre Vascular Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;65399 | &nbsp;&nbsp;&nbsp;&nbsp; 5425 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;PROCEPT BioRobotics Corp. | &nbsp;&nbsp;&nbsp;&nbsp;169052 | &nbsp;&nbsp;&nbsp;&nbsp; 5356 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Enovis Corp. | &nbsp;&nbsp;&nbsp;&nbsp;172717 | &nbsp;&nbsp;&nbsp;&nbsp; 5228 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Omnicell Inc. | &nbsp;&nbsp;&nbsp;&nbsp;139135 | &nbsp;&nbsp;&nbsp;&nbsp; 5080 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;UFP Technologies Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;22305 | &nbsp;&nbsp;&nbsp;&nbsp; 5056 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tandem Diabetes Care Inc. | &nbsp;&nbsp;&nbsp;&nbsp;205722 | &nbsp;&nbsp;&nbsp;&nbsp; 4322 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Novocure Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;322728 | &nbsp;&nbsp;&nbsp;&nbsp; 4134 |
|  | &nbsp;&nbsp;&nbsp;CONMED Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;93367 | &nbsp;&nbsp;&nbsp;&nbsp; 4054 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Axogen Inc. | &nbsp;&nbsp;&nbsp;&nbsp;139367 | &nbsp;&nbsp;&nbsp;&nbsp; 3993 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Neogen Corp. | &nbsp;&nbsp;&nbsp;&nbsp;629740 | &nbsp;&nbsp;&nbsp;&nbsp; 3766 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Establishment Labs Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;52852 | &nbsp;&nbsp;&nbsp;&nbsp; 3662 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Integra LifeSciences Holdings Corp. | &nbsp;&nbsp;&nbsp;&nbsp;201179 | &nbsp;&nbsp;&nbsp;&nbsp; 2639 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;STAAR Surgical Co. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;97157 | &nbsp;&nbsp;&nbsp;&nbsp; 2579 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;SI-BONE Inc. | &nbsp;&nbsp;&nbsp;&nbsp;124045 | &nbsp;&nbsp;&nbsp;&nbsp; 2414 |
|  | &nbsp;&nbsp;&nbsp;iRadimed Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;25160 | &nbsp;&nbsp;&nbsp;&nbsp; 2345 |
|  | &nbsp;&nbsp;&nbsp;Embecta Corp. | &nbsp;&nbsp;&nbsp;&nbsp;168839 | &nbsp;&nbsp;&nbsp;&nbsp; 2154 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Butterfly Network Inc. | &nbsp;&nbsp;&nbsp;&nbsp;614100 | &nbsp;&nbsp;&nbsp;&nbsp; 1904 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tactile Systems Technology Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;67298 | &nbsp;&nbsp;&nbsp;&nbsp; 1730 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Kestra Medical Technologies Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;62216 | &nbsp;&nbsp;&nbsp;&nbsp; 1679 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Avanos Medical Inc. | &nbsp;&nbsp;&nbsp;&nbsp;141922 | &nbsp;&nbsp;&nbsp;&nbsp; 1666 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;AngioDynamics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;123832 | &nbsp;&nbsp;&nbsp;&nbsp; 1536 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Orthofix Medical Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;95495 | &nbsp;&nbsp;&nbsp;&nbsp; 1536 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Varex Imaging Corp. | &nbsp;&nbsp;&nbsp;&nbsp;125435 | &nbsp;&nbsp;&nbsp;&nbsp; 1451 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;RxSight Inc. | &nbsp;&nbsp;&nbsp;&nbsp;105397 | &nbsp;&nbsp;&nbsp;&nbsp; 1204 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cerus Corp. | &nbsp;&nbsp;&nbsp;&nbsp;573096 | &nbsp;&nbsp;&nbsp;&nbsp; 1009 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;OrthoPediatrics Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;52941 | &nbsp;&nbsp;&nbsp;&nbsp; 979 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ceribell Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;55369 | &nbsp;&nbsp;&nbsp;&nbsp; 940 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Bioventus Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;121395 | &nbsp;&nbsp;&nbsp;&nbsp; 921 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Pulse Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;61480 | &nbsp;&nbsp;&nbsp;&nbsp; 842 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;OraSure Technologies Inc. | &nbsp;&nbsp;&nbsp;&nbsp;210885 | &nbsp;&nbsp;&nbsp;&nbsp; 502 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Treace Medical Concepts Inc. | &nbsp;&nbsp;&nbsp;&nbsp;152938 | &nbsp;&nbsp;&nbsp;&nbsp; 456 |
|  |  |  | &nbsp;&nbsp;&nbsp;&nbsp; **4112330** |
| **Health Care Providers & Services (16.5%)** | **Health Care Providers & Services (16.5%)** | **Health Care Providers & Services (16.5%)** | **Health Care Providers & Services (16.5%)** |
|  | &nbsp;&nbsp;&nbsp;UnitedHealth Group Inc. | 2582356 | &nbsp;&nbsp;&nbsp;&nbsp; 851584 |
|  | &nbsp;&nbsp;&nbsp;McKesson Corp. | &nbsp;&nbsp;&nbsp;&nbsp;377305 | &nbsp;&nbsp;&nbsp;&nbsp; 332451 |
|  | &nbsp;&nbsp;&nbsp;CVS Health Corp. | 3847482 | &nbsp;&nbsp;&nbsp;&nbsp; 309184 |
|  | &nbsp;&nbsp;&nbsp;HCA Healthcare Inc. | &nbsp;&nbsp;&nbsp;&nbsp;496871 | &nbsp;&nbsp;&nbsp;&nbsp; 252555 |
|  | &nbsp;&nbsp;&nbsp;Elevance Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;683114 | &nbsp;&nbsp;&nbsp;&nbsp; 231070 |
|  | &nbsp;&nbsp;&nbsp;Cigna Group | &nbsp;&nbsp;&nbsp;&nbsp;809752 | &nbsp;&nbsp;&nbsp;&nbsp; 224528 |
|  | &nbsp;&nbsp;&nbsp;Cencora Inc. | &nbsp;&nbsp;&nbsp;&nbsp;558694 | &nbsp;&nbsp;&nbsp;&nbsp; 206119 |
|  | &nbsp;&nbsp;&nbsp;Cardinal Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;720678 | &nbsp;&nbsp;&nbsp;&nbsp; 152971 |
|  | &nbsp;&nbsp;&nbsp;Humana Inc. | &nbsp;&nbsp;&nbsp;&nbsp;364525 | &nbsp;&nbsp;&nbsp;&nbsp; 89589 |
|  | &nbsp;&nbsp;&nbsp;Labcorp Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;251863 | &nbsp;&nbsp;&nbsp;&nbsp; 67696 |
|  | &nbsp;&nbsp;&nbsp;Quest Diagnostics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;339234 | &nbsp;&nbsp;&nbsp;&nbsp; 64176 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Centene Corp. | 1488553 | &nbsp;&nbsp;&nbsp;&nbsp; 58560 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tenet Healthcare Corp. | &nbsp;&nbsp;&nbsp;&nbsp;268044 | &nbsp;&nbsp;&nbsp;&nbsp; 58123 |
|  | &nbsp;&nbsp;&nbsp;Universal Health Services Inc. Class B | &nbsp;&nbsp;&nbsp;&nbsp;171109 | &nbsp;&nbsp;&nbsp;&nbsp; 41687 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Guardant Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;340612 | &nbsp;&nbsp;&nbsp;&nbsp; 36929 |
|  | &nbsp;&nbsp;&nbsp;Encompass Health Corp. | &nbsp;&nbsp;&nbsp;&nbsp;305697 | &nbsp;&nbsp;&nbsp;&nbsp; 35528 |
|  | &nbsp;&nbsp;&nbsp;Ensign Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;175136 | &nbsp;&nbsp;&nbsp;&nbsp; 32495 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;HealthEquity Inc. | &nbsp;&nbsp;&nbsp;&nbsp;261588 | &nbsp;&nbsp;&nbsp;&nbsp; 27514 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Henry Schein Inc. | &nbsp;&nbsp;&nbsp;&nbsp;331448 | &nbsp;&nbsp;&nbsp;&nbsp; 24716 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Molina Healthcare Inc. | &nbsp;&nbsp;&nbsp;&nbsp;164366 | &nbsp;&nbsp;&nbsp;&nbsp; 24369 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Hims & Hers Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;593650 | &nbsp;&nbsp;&nbsp;&nbsp; 23604 |
|  | &nbsp;&nbsp;&nbsp;Chemed Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;44269 | &nbsp;&nbsp;&nbsp;&nbsp; 19443 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;RadNet Inc. | &nbsp;&nbsp;&nbsp;&nbsp;198155 | &nbsp;&nbsp;&nbsp;&nbsp; 16405 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Option Care Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;491735 | &nbsp;&nbsp;&nbsp;&nbsp; 15293 |

---

------

---

| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;DaVita Inc. | &nbsp;&nbsp;&nbsp;&nbsp;119168 | &nbsp;&nbsp;&nbsp;&nbsp; 14262 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;BrightSpring Health Services Inc. | &nbsp;&nbsp;&nbsp;&nbsp;295445 | &nbsp;&nbsp;&nbsp;&nbsp; 10683 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;GeneDx Holdings Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;60930 | &nbsp;&nbsp;&nbsp;&nbsp; 10172 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Alignment Healthcare Inc. | &nbsp;&nbsp;&nbsp;&nbsp;509853 | &nbsp;&nbsp;&nbsp;&nbsp; 9794 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Brookdale Senior Living Inc. | &nbsp;&nbsp;&nbsp;&nbsp;683671 | &nbsp;&nbsp;&nbsp;&nbsp; 7609 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Privia Health Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;298498 | &nbsp;&nbsp;&nbsp;&nbsp; 7274 |
|  | &nbsp;&nbsp;&nbsp;Concentra Group Holdings Parent Inc. | &nbsp;&nbsp;&nbsp;&nbsp;351182 | &nbsp;&nbsp;&nbsp;&nbsp; 7220 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;CorVel Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;93543 | &nbsp;&nbsp;&nbsp;&nbsp; 6846 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Addus HomeCare Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;56061 | &nbsp;&nbsp;&nbsp;&nbsp; 6739 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Progyny Inc. | &nbsp;&nbsp;&nbsp;&nbsp;247826 | &nbsp;&nbsp;&nbsp;&nbsp; 6535 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Pediatrix Medical Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;263820 | &nbsp;&nbsp;&nbsp;&nbsp; 6355 |
|  | &nbsp;&nbsp;&nbsp;National HealthCare Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;39907 | &nbsp;&nbsp;&nbsp;&nbsp; 5439 |
|  | &nbsp;&nbsp;&nbsp;Select Medical Holdings Corp. | &nbsp;&nbsp;&nbsp;&nbsp;338004 | &nbsp;&nbsp;&nbsp;&nbsp; 5236 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;NeoGenomics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;392485 | &nbsp;&nbsp;&nbsp;&nbsp; 4749 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;PACS Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;140481 | &nbsp;&nbsp;&nbsp;&nbsp; 4693 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Acadia Healthcare Co. Inc. | &nbsp;&nbsp;&nbsp;&nbsp;265783 | &nbsp;&nbsp;&nbsp;&nbsp; 4571 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Surgery Partners Inc. | &nbsp;&nbsp;&nbsp;&nbsp;233734 | &nbsp;&nbsp;&nbsp;&nbsp; 3990 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Castle Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;88184 | &nbsp;&nbsp;&nbsp;&nbsp; 3523 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;LifeStance Health Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;529848 | &nbsp;&nbsp;&nbsp;&nbsp; 3444 |
|  | &nbsp;&nbsp;&nbsp;US Physical Therapy Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;46319 | &nbsp;&nbsp;&nbsp;&nbsp; 3421 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Clover Health Investments Corp. | 1269091 | &nbsp;&nbsp;&nbsp;&nbsp; 3160 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Astrana Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;136252 | &nbsp;&nbsp;&nbsp;&nbsp; 3139 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Pennant Group Inc. | &nbsp;&nbsp;&nbsp;&nbsp;105458 | &nbsp;&nbsp;&nbsp;&nbsp; 2921 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;AdaptHealth Corp. | &nbsp;&nbsp;&nbsp;&nbsp;287916 | &nbsp;&nbsp;&nbsp;&nbsp; 2781 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Hinge Health Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;49412 | &nbsp;&nbsp;&nbsp;&nbsp; 2417 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;AMN Healthcare Services Inc. | &nbsp;&nbsp;&nbsp;&nbsp;116778 | &nbsp;&nbsp;&nbsp;&nbsp; 1944 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Fulgent Genetics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;60231 | &nbsp;&nbsp;&nbsp;&nbsp; 1782 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Guardian Pharmacy Services Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;60327 | &nbsp;&nbsp;&nbsp;&nbsp; 1766 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;OPKO Health Inc. | 1280567 | &nbsp;&nbsp;&nbsp;&nbsp; 1742 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Talkspace Inc. | &nbsp;&nbsp;&nbsp;&nbsp;437806 | &nbsp;&nbsp;&nbsp;&nbsp; 1480 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Aveanna Healthcare Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;157837 | &nbsp;&nbsp;&nbsp;&nbsp; 1474 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Community Health Systems Inc. | &nbsp;&nbsp;&nbsp;&nbsp;385603 | &nbsp;&nbsp;&nbsp;&nbsp; 1334 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Enhabit Inc. | &nbsp;&nbsp;&nbsp;&nbsp;131638 | &nbsp;&nbsp;&nbsp;&nbsp; 1177 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cross Country Healthcare Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;89349 | &nbsp;&nbsp;&nbsp;&nbsp; 917 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ardent Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;86369 | &nbsp;&nbsp;&nbsp;&nbsp; 758 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Owens & Minor Inc. | &nbsp;&nbsp;&nbsp;&nbsp;234441 | &nbsp;&nbsp;&nbsp;&nbsp; 638 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;agilon health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;944468 | &nbsp;&nbsp;&nbsp;&nbsp; 615 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;DocGo Inc. | &nbsp;&nbsp;&nbsp;&nbsp;263300 | &nbsp;&nbsp;&nbsp;&nbsp; 271 |
|  |  |  | &nbsp;&nbsp;&nbsp;&nbsp; **3359460** |
| **Health Care Technology (0.8%)** | **Health Care Technology (0.8%)** | **Health Care Technology (0.8%)** | **Health Care Technology (0.8%)** |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Veeva Systems Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;472393 | &nbsp;&nbsp;&nbsp;&nbsp; 113511 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Doximity Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;371946 | &nbsp;&nbsp;&nbsp;&nbsp; 19133 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Waystar Holding Corp. | &nbsp;&nbsp;&nbsp;&nbsp;346893 | &nbsp;&nbsp;&nbsp;&nbsp; 12804 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Teladoc Health Inc. | &nbsp;&nbsp;&nbsp;&nbsp;536477 | &nbsp;&nbsp;&nbsp;&nbsp; 4072 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Phreesia Inc. | &nbsp;&nbsp;&nbsp;&nbsp;181272 | &nbsp;&nbsp;&nbsp;&nbsp; 3714 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Schrodinger Inc. | &nbsp;&nbsp;&nbsp;&nbsp;196729 | &nbsp;&nbsp;&nbsp;&nbsp; 3455 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Certara Inc. | &nbsp;&nbsp;&nbsp;&nbsp;364439 | &nbsp;&nbsp;&nbsp;&nbsp; 3338 |
|  | &nbsp;&nbsp;&nbsp;HealthStream Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;71164 | &nbsp;&nbsp;&nbsp;&nbsp; 1790 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Evolent Health Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;302531 | &nbsp;&nbsp;&nbsp;&nbsp; 1271 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Claritev Corp. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;17448 | &nbsp;&nbsp;&nbsp;&nbsp; 943 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Simulations Plus Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;52635 | &nbsp;&nbsp;&nbsp;&nbsp; 895 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;GoodRx Holdings Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;261712 | &nbsp;&nbsp;&nbsp;&nbsp; 735 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Health Catalyst Inc. | &nbsp;&nbsp;&nbsp;&nbsp;211876 | &nbsp;&nbsp;&nbsp;&nbsp; 634 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Definitive Healthcare Corp. | &nbsp;&nbsp;&nbsp;&nbsp;114215 | &nbsp;&nbsp;&nbsp;&nbsp; 324 |
|  |  |  | &nbsp;&nbsp;&nbsp;&nbsp; **166619** |
| **Life Sciences Tools & Services (9.6%)** | **Life Sciences Tools & Services (9.6%)** | **Life Sciences Tools & Services (9.6%)** | **Life Sciences Tools & Services (9.6%)** |
|  | &nbsp;&nbsp;&nbsp;Thermo Fisher Scientific Inc. | 1145526 | &nbsp;&nbsp;&nbsp;&nbsp; 676811 |
|  | &nbsp;&nbsp;&nbsp;Danaher Corp. | 1955043 | &nbsp;&nbsp;&nbsp;&nbsp; 443365 |
|  | &nbsp;&nbsp;&nbsp;Agilent Technologies Inc. | &nbsp;&nbsp;&nbsp;&nbsp;860178 | &nbsp;&nbsp;&nbsp;&nbsp; 132037 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;IQVIA Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;515266 | &nbsp;&nbsp;&nbsp;&nbsp; 118516 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Mettler-Toledo International Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;62501 | &nbsp;&nbsp;&nbsp;&nbsp; 92296 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Waters Corp. | &nbsp;&nbsp;&nbsp;&nbsp;180615 | &nbsp;&nbsp;&nbsp;&nbsp; 72864 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Illumina Inc. | &nbsp;&nbsp;&nbsp;&nbsp;465858 | &nbsp;&nbsp;&nbsp;&nbsp; 61237 |
|  | &nbsp;&nbsp;&nbsp;West Pharmaceutical Services Inc. | &nbsp;&nbsp;&nbsp;&nbsp;218166 | &nbsp;&nbsp;&nbsp;&nbsp; 60486 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Medpace Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;68204 | &nbsp;&nbsp;&nbsp;&nbsp; 40408 |
|  | &nbsp;&nbsp;&nbsp;Revvity Inc. | &nbsp;&nbsp;&nbsp;&nbsp;351794 | &nbsp;&nbsp;&nbsp;&nbsp; 36731 |
|  | &nbsp;&nbsp;&nbsp;Bio-Techne Corp. | &nbsp;&nbsp;&nbsp;&nbsp;471836 | &nbsp;&nbsp;&nbsp;&nbsp; 30438 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Repligen Corp. | &nbsp;&nbsp;&nbsp;&nbsp;162135 | &nbsp;&nbsp;&nbsp;&nbsp; 27728 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Charles River Laboratories International Inc. | &nbsp;&nbsp;&nbsp;&nbsp;149260 | &nbsp;&nbsp;&nbsp;&nbsp; 26589 |

---

------

---

| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Avantor Inc. | 1908778 | &nbsp;&nbsp;&nbsp;&nbsp; 22390 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tempus AI Inc. | &nbsp;&nbsp;&nbsp;&nbsp;281185 | &nbsp;&nbsp;&nbsp;&nbsp; 21913 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Bio-Rad Laboratories Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;56661 | &nbsp;&nbsp;&nbsp;&nbsp; 18407 |
|  | &nbsp;&nbsp;&nbsp;Bruker Corp. | &nbsp;&nbsp;&nbsp;&nbsp;322568 | &nbsp;&nbsp;&nbsp;&nbsp; 15745 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Sotera Health Co. | &nbsp;&nbsp;&nbsp;&nbsp;646066 | &nbsp;&nbsp;&nbsp;&nbsp; 11293 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Adaptive Biotechnologies Corp. | &nbsp;&nbsp;&nbsp;&nbsp;346056 | &nbsp;&nbsp;&nbsp;&nbsp; 6803 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;10X Genomics Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;311989 | &nbsp;&nbsp;&nbsp;&nbsp; 5868 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Azenta Inc. | &nbsp;&nbsp;&nbsp;&nbsp;124877 | &nbsp;&nbsp;&nbsp;&nbsp; 4441 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Fortrea Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;275658 | &nbsp;&nbsp;&nbsp;&nbsp; 3504 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;BioLife Solutions Inc. | &nbsp;&nbsp;&nbsp;&nbsp;123918 | &nbsp;&nbsp;&nbsp;&nbsp; 3284 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cytek Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;329039 | &nbsp;&nbsp;&nbsp;&nbsp; 1859 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Pacific Biosciences of California Inc. | &nbsp;&nbsp;&nbsp;&nbsp;783916 | &nbsp;&nbsp;&nbsp;&nbsp; 1819 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Personalis Inc. | &nbsp;&nbsp;&nbsp;&nbsp;160924 | &nbsp;&nbsp;&nbsp;&nbsp; 1727 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;CryoPort Inc. | &nbsp;&nbsp;&nbsp;&nbsp;144077 | &nbsp;&nbsp;&nbsp;&nbsp; 1386 |
|  | &nbsp;&nbsp;&nbsp;Mesa Laboratories Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;16692 | &nbsp;&nbsp;&nbsp;&nbsp; 1339 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Maravai LifeSciences Holdings Inc. Class A | &nbsp;&nbsp;&nbsp;&nbsp;328667 | &nbsp;&nbsp;&nbsp;&nbsp; 1190 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Niagen Bioscience Inc. | &nbsp;&nbsp;&nbsp;&nbsp;173200 | &nbsp;&nbsp;&nbsp;&nbsp; 1173 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Standard BioTools Inc. | &nbsp;&nbsp;&nbsp;&nbsp;752686 | &nbsp;&nbsp;&nbsp;&nbsp; 1129 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ginkgo Bioworks Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;99826 | &nbsp;&nbsp;&nbsp;&nbsp; 926 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Quanterix Corp. | &nbsp;&nbsp;&nbsp;&nbsp;126592 | &nbsp;&nbsp;&nbsp;&nbsp; 919 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Quantum-Si Inc. | &nbsp;&nbsp;&nbsp;&nbsp;496879 | &nbsp;&nbsp;&nbsp;&nbsp; 701 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MaxCyte Inc. | &nbsp;&nbsp;&nbsp;&nbsp;306637 | &nbsp;&nbsp;&nbsp;&nbsp; 540 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;OmniAb Inc. | &nbsp;&nbsp;&nbsp;&nbsp;261425 | &nbsp;&nbsp;&nbsp;&nbsp; 473 |
| <sup>\*,2</sup> | &nbsp;&nbsp;&nbsp;OmniAb Inc. 12.5 Earnout | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;22076 | &nbsp;&nbsp;&nbsp;&nbsp; — |
| <sup>\*,2</sup> | &nbsp;&nbsp;&nbsp;OmniAb Inc. 15 Earnout | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;22076 | &nbsp;&nbsp;&nbsp;&nbsp; — |
|  |  |  | &nbsp;&nbsp;&nbsp;&nbsp; **1948335** |
| **Pharmaceuticals (27.6%)** | **Pharmaceuticals (27.6%)** | **Pharmaceuticals (27.6%)** | **Pharmaceuticals (27.6%)** |
|  | &nbsp;&nbsp;&nbsp;Eli Lilly & Co. | 2440385 | &nbsp;&nbsp;&nbsp;&nbsp; 2624561 |
|  | &nbsp;&nbsp;&nbsp;Johnson & Johnson | 4529546 | &nbsp;&nbsp;&nbsp;&nbsp; 937254 |
|  | &nbsp;&nbsp;&nbsp;Merck & Co. Inc. | 7577046 | &nbsp;&nbsp;&nbsp;&nbsp; 794302 |
|  | &nbsp;&nbsp;&nbsp;Pfizer Inc. | 17248049 | &nbsp;&nbsp;&nbsp;&nbsp; 443965 |
|  | &nbsp;&nbsp;&nbsp;Bristol-Myers Squibb Co. | 6174845 | &nbsp;&nbsp;&nbsp;&nbsp; 303802 |
|  | &nbsp;&nbsp;&nbsp;Zoetis Inc. | 1343247 | &nbsp;&nbsp;&nbsp;&nbsp; 172177 |
|  | &nbsp;&nbsp;&nbsp;Viatris Inc. | 3533778 | &nbsp;&nbsp;&nbsp;&nbsp; 37776 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Elanco Animal Health Inc. (XNYS) | 1508112 | &nbsp;&nbsp;&nbsp;&nbsp; 35094 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Jazz Pharmaceuticals plc | &nbsp;&nbsp;&nbsp;&nbsp;165749 | &nbsp;&nbsp;&nbsp;&nbsp; 29260 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Corcept Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;287418 | &nbsp;&nbsp;&nbsp;&nbsp; 22821 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Axsome Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;105864 | &nbsp;&nbsp;&nbsp;&nbsp; 16038 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Crinetics Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;271132 | &nbsp;&nbsp;&nbsp;&nbsp; 12353 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ligand Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;59379 | &nbsp;&nbsp;&nbsp;&nbsp; 12065 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Indivior plc | &nbsp;&nbsp;&nbsp;&nbsp;265817 | &nbsp;&nbsp;&nbsp;&nbsp; 8931 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Prestige Consumer Healthcare Inc. | &nbsp;&nbsp;&nbsp;&nbsp;149197 | &nbsp;&nbsp;&nbsp;&nbsp; 8885 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Supernus Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;170712 | &nbsp;&nbsp;&nbsp;&nbsp; 7783 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Tarsus Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;95934 | &nbsp;&nbsp;&nbsp;&nbsp; 7671 |
|  | &nbsp;&nbsp;&nbsp;Organon & Co. | &nbsp;&nbsp;&nbsp;&nbsp;787397 | &nbsp;&nbsp;&nbsp;&nbsp; 6071 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Amneal Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;477912 | &nbsp;&nbsp;&nbsp;&nbsp; 5983 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Liquidia Corp. | &nbsp;&nbsp;&nbsp;&nbsp;183354 | &nbsp;&nbsp;&nbsp;&nbsp; 5983 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ocular Therapeutix Inc. | &nbsp;&nbsp;&nbsp;&nbsp;481791 | &nbsp;&nbsp;&nbsp;&nbsp; 5854 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Avadel Pharmaceuticals plc | &nbsp;&nbsp;&nbsp;&nbsp;265396 | &nbsp;&nbsp;&nbsp;&nbsp; 5703 |
|  | &nbsp;&nbsp;&nbsp;Perrigo Co. plc | &nbsp;&nbsp;&nbsp;&nbsp;416410 | &nbsp;&nbsp;&nbsp;&nbsp; 5559 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Nuvation Bio Inc. | &nbsp;&nbsp;&nbsp;&nbsp;672062 | &nbsp;&nbsp;&nbsp;&nbsp; 5397 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Terns Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;173318 | &nbsp;&nbsp;&nbsp;&nbsp; 4872 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Harmony Biosciences Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;131378 | &nbsp;&nbsp;&nbsp;&nbsp; 4636 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;ANI Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;54011 | &nbsp;&nbsp;&nbsp;&nbsp; 4583 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Collegium Pharmaceutical Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;95416 | &nbsp;&nbsp;&nbsp;&nbsp; 4454 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Edgewise Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;160267 | &nbsp;&nbsp;&nbsp;&nbsp; 4173 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Harrow Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;96122 | &nbsp;&nbsp;&nbsp;&nbsp; 4016 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Innoviva Inc. | &nbsp;&nbsp;&nbsp;&nbsp;182163 | &nbsp;&nbsp;&nbsp;&nbsp; 3958 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Amylyx Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;248251 | &nbsp;&nbsp;&nbsp;&nbsp; 3719 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Xeris Biopharma Holdings Inc. | &nbsp;&nbsp;&nbsp;&nbsp;488020 | &nbsp;&nbsp;&nbsp;&nbsp; 3504 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Trevi Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;257890 | &nbsp;&nbsp;&nbsp;&nbsp; 3402 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Nektar Therapeutics | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;48916 | &nbsp;&nbsp;&nbsp;&nbsp; 3190 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Amphastar Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;112509 | &nbsp;&nbsp;&nbsp;&nbsp; 3116 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Mind Medicine MindMed Inc. | &nbsp;&nbsp;&nbsp;&nbsp;242440 | &nbsp;&nbsp;&nbsp;&nbsp; 3067 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Pacira BioSciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;129303 | &nbsp;&nbsp;&nbsp;&nbsp; 3048 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Esperion Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;700704 | &nbsp;&nbsp;&nbsp;&nbsp; 2810 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;EyePoint Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;187945 | &nbsp;&nbsp;&nbsp;&nbsp; 2787 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Tilray Brands Inc. | 3402201 | &nbsp;&nbsp;&nbsp;&nbsp; 2766 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;WaVe Life Sciences Ltd. | &nbsp;&nbsp;&nbsp;&nbsp;340828 | &nbsp;&nbsp;&nbsp;&nbsp; 2645 |

---

------

---

| | | | |
|:---|:---|:---|:---|
|  |  | Shares | &nbsp;&nbsp;&nbsp;&nbsp;Market<br> Value<br> ($000) |
|  | &nbsp;&nbsp;&nbsp;Phibro Animal Health Corp. Class A | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;62293 | &nbsp;&nbsp;&nbsp;&nbsp; 2609 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Rapport Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;84353 | &nbsp;&nbsp;&nbsp;&nbsp; 2506 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Arvinas Inc. | &nbsp;&nbsp;&nbsp;&nbsp;189036 | &nbsp;&nbsp;&nbsp;&nbsp; 2379 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Theravance Biopharma Inc. | &nbsp;&nbsp;&nbsp;&nbsp;115057 | &nbsp;&nbsp;&nbsp;&nbsp; 2336 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;MBX Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;67620 | &nbsp;&nbsp;&nbsp;&nbsp; 2332 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;CorMedix Inc. | &nbsp;&nbsp;&nbsp;&nbsp;224303 | &nbsp;&nbsp;&nbsp;&nbsp; 2200 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Enliven Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;99212 | &nbsp;&nbsp;&nbsp;&nbsp; 2143 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Omeros Corp. | &nbsp;&nbsp;&nbsp;&nbsp;205912 | &nbsp;&nbsp;&nbsp;&nbsp; 1995 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Phathom Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;127712 | &nbsp;&nbsp;&nbsp;&nbsp; 1995 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Ventyx Biosciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;172830 | &nbsp;&nbsp;&nbsp;&nbsp; 1728 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Fulcrum Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;114515 | &nbsp;&nbsp;&nbsp;&nbsp; 1253 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Alumis Inc. | &nbsp;&nbsp;&nbsp;&nbsp;161421 | &nbsp;&nbsp;&nbsp;&nbsp; 1238 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;LENZ Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;35381 | &nbsp;&nbsp;&nbsp;&nbsp; 1080 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Evolus Inc. | &nbsp;&nbsp;&nbsp;&nbsp;145573 | &nbsp;&nbsp;&nbsp;&nbsp; 1042 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Septerna Inc. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;33708 | &nbsp;&nbsp;&nbsp;&nbsp; 978 |
|  | &nbsp;&nbsp;&nbsp;SIGA Technologies Inc. | &nbsp;&nbsp;&nbsp;&nbsp;131269 | &nbsp;&nbsp;&nbsp;&nbsp; 795 |
| <sup>\*,1</sup> | &nbsp;&nbsp;&nbsp;Lexicon Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;552580 | &nbsp;&nbsp;&nbsp;&nbsp; 790 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Atea Pharmaceuticals Inc. | &nbsp;&nbsp;&nbsp;&nbsp;156105 | &nbsp;&nbsp;&nbsp;&nbsp; 484 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Cassava Sciences Inc. | &nbsp;&nbsp;&nbsp;&nbsp;134135 | &nbsp;&nbsp;&nbsp;&nbsp; 436 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Neumora Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;172278 | &nbsp;&nbsp;&nbsp;&nbsp; 386 |
| <sup>\*</sup> | &nbsp;&nbsp;&nbsp;Pliant Therapeutics Inc. | &nbsp;&nbsp;&nbsp;&nbsp;116234 | &nbsp;&nbsp;&nbsp;&nbsp; 187 |
| <sup>\*,2</sup> | &nbsp;&nbsp;&nbsp;Chinook Therapeutics Inc. CVR | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;784 | &nbsp;&nbsp;&nbsp;&nbsp; — |
|  |  |  | &nbsp;&nbsp;&nbsp;&nbsp; **5610926** |
| **Total Common Stocks (Cost $14,610,205)** | **Total Common Stocks (Cost $14,610,205)** | **Total Common Stocks (Cost $14,610,205)** | &nbsp;&nbsp;&nbsp;&nbsp;**19520767** |
| **Temporary Cash Investments (4.0%)** | **Temporary Cash Investments (4.0%)** | **Temporary Cash Investments (4.0%)** | **Temporary Cash Investments (4.0%)** |
| **Money Market Fund (4.0%)** | **Money Market Fund (4.0%)** | **Money Market Fund (4.0%)** | **Money Market Fund (4.0%)** |
| <sup>3,4</sup> | &nbsp;&nbsp;&nbsp;Vanguard Market Liquidity Fund, 4.024% **(Cost $819,727)** | 8197953 | &nbsp;&nbsp;&nbsp;&nbsp; **819796** |
| **Total Investments (99.9%) (Cost $15,429,932)** | **Total Investments (99.9%) (Cost $15,429,932)** | **Total Investments (99.9%) (Cost $15,429,932)** | &nbsp;&nbsp;&nbsp;&nbsp;**20340563** |
| **Other Assets and Liabilities—Net (0.1%)** | **Other Assets and Liabilities—Net (0.1%)** | **Other Assets and Liabilities—Net (0.1%)** | &nbsp;&nbsp;&nbsp;&nbsp;**21660** |
| **Net Assets (100.0%)** | **Net Assets (100.0%)** | **Net Assets (100.0%)** | &nbsp;&nbsp;&nbsp;&nbsp;**20362223** |
| Cost is in $000. | Cost is in $000. | Cost is in $000. | Cost is in $000. |

---

---

| | |
|:---|:---|
| \* | Non-income-producing security. |
| 1 | Includes partial security positions on loan to broker-dealers. The total value of securities on loan is $19,580. |
| 2 | Security value determined using significant unobservable inputs. |
| 3 | Affiliated money market fund available only to Vanguard funds and certain trusts and accounts managed by Vanguard. Rate shown is the 7-day yield. |
| 4 | Collateral of $24,647 was received for securities on loan. |

---

CVR—Contingent Value Rights.

------

#### Derivative Financial Instruments Outstanding as of Period End

------

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| Over-the-Counter Total Return Swaps | Over-the-Counter Total Return Swaps | Over-the-Counter Total Return Swaps | Over-the-Counter Total Return Swaps | Over-the-Counter Total Return Swaps | Over-the-Counter Total Return Swaps | Over-the-Counter Total Return Swaps |
| Reference Entity | Termination<br> Date | &nbsp;&nbsp;&nbsp;Counterparty | &nbsp;&nbsp;&nbsp;Notional<br> Amount<br> ($000) | &nbsp;&nbsp;&nbsp;Floating<br> Interest Rate<br> Received<br> (Paid)<sup>1</sup><br> (%) | &nbsp;&nbsp;&nbsp;Value and<br> Unrealized<br> Appreciation<br> ($000) | &nbsp;&nbsp;&nbsp;Value and<br> Unrealized<br> (Depreciation)<br> ($000) |
| AbbVie Inc. | 8/31/2026 | &nbsp;&nbsp;&nbsp;BANA | &nbsp;&nbsp;&nbsp;197030 | &nbsp;&nbsp;&nbsp;(4.580) | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;(3610) |
| Avantor Inc. | 8/31/2026 | &nbsp;&nbsp;&nbsp;BANA | &nbsp;&nbsp;&nbsp;1920 | &nbsp;&nbsp;&nbsp;(3.880) | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;(20) |
| Globus Medical Inc. | 8/31/2026 | &nbsp;&nbsp;&nbsp;BANA | &nbsp;&nbsp;&nbsp;9118 | &nbsp;&nbsp;&nbsp;(3.880) | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;(19) |
| Johnson & Johnson | &nbsp;&nbsp;&nbsp;2/2/2026 | &nbsp;&nbsp;&nbsp;GSI | &nbsp;&nbsp;&nbsp;19958 | &nbsp;&nbsp;&nbsp;(3.880) | &nbsp;&nbsp;&nbsp;842 | &nbsp;&nbsp;&nbsp;— |
| Johnson & Johnson | 8/31/2026 | &nbsp;&nbsp;&nbsp;BANA | &nbsp;&nbsp;&nbsp;553049 | &nbsp;&nbsp;&nbsp;(4.580) | &nbsp;&nbsp;&nbsp;3796 | &nbsp;&nbsp;&nbsp;— |
| UnitedHealth Group Inc. | 8/31/2026 | &nbsp;&nbsp;&nbsp;BANA | &nbsp;&nbsp;&nbsp;53836 | &nbsp;&nbsp;&nbsp;(4.530) | &nbsp;&nbsp;&nbsp;542 | &nbsp;&nbsp;&nbsp;— |
|  |  |  |  |  | &nbsp;&nbsp;&nbsp;5180 | &nbsp;&nbsp;&nbsp;(3649) |

---

1 Based on Overnight Bank Funding Rate as of the most recent reset date. Floating interest payment received/(paid) monthly. <br> BANA—Bank of America, N.A. <br> GSI—Goldman Sachs International.

At November 30, 2025, the counterparties had deposited in segregated accounts securities with a value of $4,330 in connection with open over-the-counter swap contracts.

**A.** Security Valuation: Securities are valued as of the close of trading on the New York Stock Exchange (generally 4 p.m., Eastern time) on the valuation date. Equity securities are valued at the latest quoted sales
prices or official closing prices taken from the primary market in which each

------

security trades; such securities not traded on the valuation date are valued at the mean of the latest quoted bid and asked prices. Securities for which market quotations are not readily available, or whose values have been affected by events occurring before the fund's pricing time but after the close of the securities' primary markets, are valued by methods deemed by the valuation designee to represent fair value and subject to oversight by the board of trustees. Investments in Vanguard Market Liquidity Fund are valued at that fund's net asset value.

**B.** Swap Contracts: The fund has entered into equity swap contracts to earn the total return on selected reference stocks or indexes in the fund's target index. Under the terms of the swaps, the fund receives the
total return on the referenced stock (i.e., receiving the increase or paying the decrease in value of the selected reference stock and receiving the equivalent of any dividends in respect of the selected referenced
stock) over a specified period of time, applied to a notional amount that represents the value of a designated number of shares of the selected reference stock at the beginning of the equity swap contract. The fund
also pays a floating rate that is based on short-term interest rates, applied to the notional amount. At the same time, the fund generally invests an amount approximating the notional amount of the swap in
high-quality temporary cash investments.

A risk associated with all types of swaps is the possibility that a counterparty may default on its obligation to pay net amounts due to the fund. The fund's maximum amount subject to counterparty risk is the unrealized appreciation on the swap contract. The fund mitigates its counterparty risk by entering into swaps only with a diverse group of prequalified counterparties, monitoring their financial strength, entering into master netting arrangements with its counterparties, and requiring its counterparties to transfer collateral as security for their performance. In the absence of a default, the collateral pledged or received by the fund cannot be repledged, resold, or rehypothecated. In the event of a counterparty's default (including bankruptcy), the fund may terminate any swap contracts with that counterparty, determine the net amount owed by either party in accordance with its master netting arrangements, and sell or retain any collateral held up to the net amount owed to the fund under the master netting arrangements. The swap contracts contain provisions whereby a counterparty may terminate open contracts if the fund's net assets decline below a certain level, triggering a payment by the fund if the fund is in a net liability position at the time of the termination. The payment amount would be reduced by any collateral the fund has pledged. Any securities pledged as collateral for open contracts are noted in the Schedule of Investments. The value of collateral received or pledged is compared daily to the value of the swap contracts exposure with each counterparty, and any difference, if in excess of a specified minimum transfer amount, is adjusted and settled within two business days.

Swaps are valued daily based on market quotations received from independent pricing services or recognized dealers and the change in value is recorded as an asset (liability) and as unrealized appreciation (depreciation) until periodic payments are made or the termination of the swap, at which time realized gain (loss) is recorded.

**C.** Various inputs may be used to determine the value of the fund's investments and derivatives. These inputs are summarized in three broad levels for financial statement purposes. The inputs or methodologies used
to value securities are not necessarily an indication of the risk associated with investing in those securities.

#### Level 1 —Quoted prices in active markets for identical securities.

#### Level 2 —Other significant observable inputs (including quoted prices for similar securities, interest rates, prepayment speeds, credit risk, etc.).
**Level 3—Significant unobservable inputs (including the fund's own assumptions used to determine the fair value of investments). Any investments and derivatives valued with significant unobservable inputs are noted on the Schedule of Investments.**

The following table summarizes the market value of the fund's investments and derivatives as of November 30, 2025, based on the inputs used to value them:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | Level 1<br> ($000) | &nbsp;&nbsp;&nbsp;Level 2<br> ($000) | &nbsp;&nbsp;&nbsp;Level 3<br> ($000) | &nbsp;&nbsp;&nbsp;Total<br> ($000) |
| **Investments** |  |  |  |  |
| Assets |  |  |  |  |
| Common Stocks | 19520767 | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;19520767 |
| Temporary Cash Investments | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;819796 | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;819796 |
| Total | 20340563 | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;20340563 |
| **Derivative Financial Instruments** |  |  |  |  |
| Assets |  |  |  |  |
| Swap Contracts |  | &nbsp;&nbsp;&nbsp;&nbsp;5180 | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;&nbsp;5180 |
| Liabilities |  |  |  |  |
| Swap Contracts |  | &nbsp;&nbsp;&nbsp;(3649) | &nbsp;&nbsp;&nbsp;— | &nbsp;&nbsp;&nbsp;(3649) |

---

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** VANGUARD WORLD FUND

- **b. Investment Company Act file number:** 811-01027

- **c. CIK number of Registrant:** 0000052848

- **d. LEI of Registrant:** 549300MP6BT0L4Q61L10

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 100 Vanguard Boulevard

  - **City:** Malvern

  - **State:** PA

  - **Foreign country:** US

  - **Zip / Postal Code:** 19355

  - **Telephone number:** 610-669-1000

**Item A.2. Information about the Series.**

- **a. Name of Series:** VANGUARD HEALTH CARE INDEX FUND

- **b. EDGAR series identifier (if any):** S000004450

- **c. LEI of Series:** 4G9X037GNB6OUK17TK21

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-08-31

- **b. Date as of which information is reported:** 2025-11-30

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $20371827285.60

**Total Liabilities:** $2933212.67

**Net Assets:** $20368894072.93

**Cash Not Reported:** $11922312.40

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000012223 | 2.26%                | 4.05%                | 8.99%                |
| Class ID C000012222 | 2.26%                | 4.06%                | 8.99%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $76275880.73             | $243723393.02                              |
| Month 2  | $-31232077.78            | $643566296.40                              |
| Month 3  | $-47557610.45            | $1558205735.11                             |

### Schedule of Portfolio Investments

| Name                                              | Title                                      | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)    | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Surgery Partners Inc                              | SURGERY PARTNERS                           | CUSIP: 86881A100<br>LEI: 549300LC82HG33S19I03 | Long             | EC               | CORP              | US        |    233818 | NS      | $3991273.26    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Varex Imaging Corp                                | VAREX IMAGIN                               | CUSIP: 92214X106<br>LEI: 549300CWYWPVCT8E9W67 | Long             | EC               | CORP              | US        |    125481 | NS      | $1451815.17    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                                      | REZOLUTE INC                               | CUSIP: 76200L309<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    219940 | NS      | $2137816.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Prevail Therapeutics Inc                          | PREVAIL THERAPEU - CVR                     | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |        78 | NS      | $39.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Disc Medicine Inc                                 | DISC MEDICINE IN                           | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     73777 | NS      | $6887820.72    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:JOHNSON & JOHNSON USD 2026-Aug-31      | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |   2676000 | NC      | $669000.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Pieris Pharmaceuticals Inc                        | PALVELLA THERAPE                           | CUSIP: 697947109<br>LEI: 254900AJDH8PAOOI5T33 | Long             | EC               | CORP              | US        |     21755 | NS      | $2236196.45    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Alumis Inc                                        | ALUMIS INC                                 | CUSIP: 022307102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    161479 | NS      | $1238543.93    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                                       | HOLOGIC INC                                | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |    675006 | NS      | $50605199.82   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| CG oncology Inc                                   | CG ONCOLOGY INC                            | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    129673 | NS      | $5814537.32    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Chemed Corp                                       | CHEMED CORP                                | CUSIP: 16359R103<br>LEI: 54930020031IDJT2IM79 | Long             | EC               | CORP              | US        |     44285 | NS      | $19449529.15   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Embecta Corp                                      | EMBECTA CORP                               | CUSIP: 29082K105<br>LEI: 549300RPG8GXVDHNXZ62 | Long             | EC               | CORP              | US        |    168900 | NS      | $2154319.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Terns Pharmaceuticals Inc                         | TERNS PHARMACEUT                           | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |    173380 | NS      | $4873711.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc                      | THERMO FISHER                              | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |   1145940 | NS      | $677055730.20  | 3.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Olema Pharmaceuticals Inc                         | OLEMA PHARMACEUT                           | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    114435 | NS      | $3240799.20    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Penumbra Inc                                      | PENUMBRA INC                               | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |    112485 | NS      | $32977227.45   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Avantor Inc                                       | AVANTOR INC                                | CUSIP: 05352A100<br>LEI: 5493003VM0XB4U8YD238 | Long             | EC               | CORP              | US        |   1909526 | NS      | $22398739.98   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp                         | ANAVEX LIFE SCIE                           | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |    257903 | NS      | $987768.49     | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Exelixis Inc                                      | EXELIXIS INC                               | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |    776592 | NS      | $34302068.64   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Mind Medicine MindMed Inc                         | MIND MEDICINE MI                           | CUSIP: 60255C885<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | US        |    242528 | NS      | $3067979.20    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Option Care Health Inc                            | OPTION CARE HEAL                           | CUSIP: 68404L201<br>LEI: 549300DI3Q5ACSYJRI17 | Long             | EC               | CORP              | US        |    491913 | NS      | $15298494.30   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| GE HealthCare Technologies Inc                    | GE HEALTHCARE TE                           | CUSIP: 36266G107<br>LEI: 549300OI9J7XOWZMUN85 | Long             | EC               | CORP              | US        |   1385679 | NS      | $110840463.21  | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Zimmer Biomet Holdings Inc                        | ZIMMER BIOMET HO                           | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |    601276 | NS      | $58636435.52   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Kiniksa Pharmaceuticals International Plc         | KINIKSA PHARMACE                           | CUSIP: G52694109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    105411 | NS      | $4482075.72    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Medtronic PLC                                     | MEDTRONIC PLC                              | CUSIP: G5960L103<br>LEI: 549300GX3ZBSQWUXY261 | Long             | EC               | CORP              | US        |   3892421 | NS      | $409988703.93  | 2.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Prime Medicine Inc                                | PRIME MEDICINE I                           | CUSIP: 74168J101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    261417 | NS      | $998612.94     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Amicus Therapeutics Inc                           | AMICUS THERAPEUT                           | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |    840845 | NS      | $8349590.85    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Health Catalyst Inc                               | HEALTH CATALYST                            | CUSIP: 42225T107<br>LEI: 549300223PL6GWKVJG92 | Long             | EC               | CORP              | US        |    211953 | NS      | $633739.47     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Keros Therapeutics Inc                            | KEROS THERAPEUTI                           | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     52251 | NS      | $913347.48     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc                              | ALIGN TECHNOLOGY                           | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |    208872 | NS      | $30743869.68   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Phibro Animal Health Corp                         | PHIBRO ANIMAL-A                            | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |     62315 | NS      | $2609752.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Progyny Inc                                       | PROGYNY INC                                | CUSIP: 74340E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    247916 | NS      | $6537544.92    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Simulations Plus Inc                              | SIMULATIONS PLUS                           | CUSIP: 829214105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     52654 | NS      | $895118.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Haemonetics Corp                                  | HAEMONETICS CORP                           | CUSIP: 405024100<br>LEI: 549300ZEL6TXZS6F5F95 | Long             | EC               | CORP              | US        |    146076 | NS      | $11883282.60   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Quest Diagnostics Inc                             | QUEST DIAGNOSTIC                           | CUSIP: 74834L100<br>LEI: 8MCWUBXQ0WE04KMXBX50 | Long             | EC               | CORP              | US        |    339357 | NS      | $64199557.26   | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Innoviva Inc                                      | INNOVIVA INC                               | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |    182229 | NS      | $3959836.17    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc                          | CELLDEX THERAPEU                           | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |    181219 | NS      | $4896537.38    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Pediatrix Medical Group Inc                       | PEDIATRIX MEDICA                           | CUSIP: 58502B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    263916 | NS      | $6357736.44    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| BioCryst Pharmaceuticals Inc                      | BIOCRYST PHARM                             | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    604428 | NS      | $4339793.04    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Envista Holdings Corp                             | ENVISTA HOLDINGS                           | CUSIP: 29415F104<br>LEI: 549300BX623VURJZ5269 | Long             | EC               | CORP              | US        |    503665 | NS      | $10526598.50   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corp PLC                                 | PROTHENA CORP PL                           | CUSIP: G72800108<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | US        |    138710 | NS      | $1491132.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Zenas Biopharma Inc                               | ZENAS BIOPHARMA                            | CUSIP: 98937L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     48507 | NS      | $1883526.81    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| United Therapeutics Corp                          | UNITED THERAPEUT                           | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |    130390 | NS      | $63369540.00   | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara Inc                                        | SAVARA INC                                 | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |    209508 | NS      | $1317805.32    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc                                         | AMGEN INC                                  | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |   1633701 | NS      | $564378347.46  | 2.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc                         | HALOZYME THERAPE                           | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |    355343 | NS      | $25371490.20   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Perrigo Co PLC                                    | PERRIGO CO PLC                             | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | US        |    416561 | NS      | $5561089.35    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc                           | AXSOME THERAPEUT                           | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |    105902 | NS      | $16044153.00   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunome Inc                                      | IMMUNOME INC                               | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    212576 | NS      | $3915649.92    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc                                        | ABBVIE INC                                 | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |   4510705 | NS      | $1027087528.50 | 5.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp                            | ARBUTUS BIOPHARM                           | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | US        |    435510 | NS      | $1920599.10    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacific Biosciences of California Inc             | PACIFIC BIOSCIEN                           | CUSIP: 69404D108<br>LEI: 529900F1BWRE1M0KZN89 | Long             | EC               | CORP              | US        |    784196 | NS      | $1819334.72    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| LENZ Therapeutics Inc                             | LENZ THERAPEUTIC                           | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     35394 | NS      | $1080224.88    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                                      | DOXIMITY INC-A                             | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    372081 | NS      | $19139846.64   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| BioLife Solutions Inc                             | BIOLIFE SOLUTION                           | CUSIP: 09062W204<br>LEI: 549300G2IVCMC2TJDW72 | Long             | EC               | CORP              | US        |    123963 | NS      | $3285019.50    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Entrada Therapeutics Inc                          | ENTRADA THERAPEU                           | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     58039 | NS      | $596060.53     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc                         | CULLINAN THERAPE                           | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     89472 | NS      | $1017296.64    | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings Inc                  | HARMONY BIOSCIE                            | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    131425 | NS      | $4637988.25    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals Inc                      | KALVISTA PHARMAC                           | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |     84218 | NS      | $1218634.46    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Stryker Corp                                      | STRYKER CORP                               | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |   1044140 | NS      | $387563885.20  | 1.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor Inc                                        | XENCOR INC                                 | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |    182975 | NS      | $3169127.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Soleno Therapeutics Inc                           | SOLENO THERAPEUT                           | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |    136927 | NS      | $6907967.15    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Orthofix Medical Inc                              | ORTHOFIX MEDICAL                           | CUSIP: 68752M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95530 | NS      | $1537077.70    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytek Biosciences Inc                             | CYTEK BIOSCIENCE                           | CUSIP: 23285D109<br>LEI: 549300K2J28BOC6FBO89 | Long             | EC               | CORP              | US        |    329158 | NS      | $1859742.70    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MiMedx Group Inc                                  | MIMEDX GROUP INC                           | CUSIP: 602496101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    360293 | NS      | $2478815.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc                                        | RESMED INC                                 | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |    442475 | NS      | $113198379.25  | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc                           | KYMERA THERAPEUT                           | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    119613 | NS      | $8119330.44    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics Inc                          | SAREPTA THERAPEU                           | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |    301410 | NS      | $6432089.40    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corp                                       | WATERS CORP                                | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |    180680 | NS      | $72889925.60   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| TG Therapeutics Inc                               | TG THERAPEUTICS                            | CUSIP: 88322Q108<br>LEI: 529900X21UKABN9NJ529 | Long             | EC               | CORP              | US        |    457477 | NS      | $15215685.02   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics Inc                            | TANGO THERAPEUTI                           | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    137700 | NS      | $1502307.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ligand Pharmaceuticals Inc                        | LIGAND PHARM                               | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |     59400 | NS      | $12068892.00   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc                           | APOGEE THERAPEUT                           | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96629 | NS      | $6954389.13    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Applied Therapeutics Inc                          | APPLIED THERAPEU                           | CUSIP: 03828A101<br>LEI: 549300KL3IJPHZM2GR04 | Long             | EC               | CORP              | US        |    326572 | NS      | $84908.72      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corp                             | TWIST BIOSCIENCE                           | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |    183788 | NS      | $5883053.88    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| DaVita Inc                                        | DAVITA INC                                 | CUSIP: 23918K108<br>LEI: M2XHYMU3TZNEZURC6H66 | Long             | EC               | CORP              | US        |    119211 | NS      | $14267172.48   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Solventum Corp                                    | SOLVENTUM                                  | CUSIP: 83444M101<br>LEI: 254900I70403OSGY4M28 | Long             | EC               | CORP              | US        |    472608 | NS      | $40294558.08   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| GeneDx Holdings Corp                              | GENEDX HOLDINGS                            | CUSIP: 81663L200<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     60952 | NS      | $10175936.40   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Alignment Healthcare Inc                          | ALIGNMENT HEALTH                           | CUSIP: 01625V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    510038 | NS      | $9797829.98    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| AdaptHealth Corp                                  | ADAPTHEALTH CORP                           | CUSIP: 00653Q102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    288020 | NS      | $2782273.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Dyne Therapeutics Inc                             | DYNE THERAPEUTIC                           | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    280346 | NS      | $6139577.40    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Medpace Holdings Inc                              | MEDPACE HOLDINGS                           | CUSIP: 58506Q109<br>LEI: 549300H8TYEUVTW14A54 | Long             | EC               | CORP              | US        |     68229 | NS      | $40422953.34   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Avidity Biosciences Inc                           | AVIDITY BIOSCIEN                           | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    331777 | NS      | $23788410.90   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Precigen Inc                                      | PRECIGEN INC                               | CUSIP: 74017N105<br>LEI: 549300XCWNQU35K64G19 | Long             | EC               | CORP              | US        |    535924 | NS      | $2052588.92    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Nektar Therapeutics                               | NEKTAR THERAPEUT                           | CUSIP: 640268306<br>LEI: 5299005I24806IOIYE03 | Long             | EC               | CORP              | US        |     48934 | NS      | $3190986.14    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Certara Inc                                       | CERTARA INC                                | CUSIP: 15687V109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    364571 | NS      | $3339470.36    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| OPKO Health Inc                                   | OPKO HEALTH                                | CUSIP: 68375N103<br>LEI: 529900A4S2D4OGOJLL02 | Long             | EC               | CORP              | US        |   1281031 | NS      | $1742202.16    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Phreesia Inc                                      | PHREESIA INC                               | CUSIP: 71944F106<br>LEI: 5493000HHF8NU4QOCG53 | Long             | EC               | CORP              | US        |    181338 | NS      | $3715615.62    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Korro Bio Inc                                     | KORRO BIO INC                              | CUSIP: 500946108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13903 | NS      | $79247.10      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Hims & Hers Health Inc                            | HIMS & HERS HEAL                           | CUSIP: 433000106<br>LEI: 549300ZQ4ZUYSAAX6P59 | Long             | EC               | CORP              | US        |    593865 | NS      | $23612072.40   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Bristol-Myers Squibb Co                           | BRISTOL-MYER SQB                           | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |   6177078 | NS      | $303912237.60  | 1.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Cigna Group/The                                   | THE CIGNA GROUP                            | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |    810045 | NS      | $224609277.60  | 1.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvalent Inc                                      | NUVALENT INC-A                             | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    121286 | NS      | $13262624.10   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc                                | IQVIA HOLDINGS I                           | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |    515452 | NS      | $118559114.52  | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| WaVe Life Sciences Ltd                            | WAVE LIFE SCIENC                           | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | US        |    340950 | NS      | $2645772.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                              | ROIVANT SCIENCES                           | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | US        |   1140994 | NS      | $23744085.14   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Rocket Pharmaceuticals Inc                        | ROCKET PHARMACEU                           | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |    246142 | NS      | $841805.64     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Arrowhead Pharmaceuticals Inc                     | ARROWHEAD PHARMA                           | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |    377205 | NS      | $19878703.50   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc                         | DIANTHUS THERAPE                           | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |     48244 | NS      | $2121771.12    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp                     | ADAPTIVE BIOTECH                           | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |    346181 | NS      | $6805918.46    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:ABBVIE INC USD 2026-Aug-31             | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    850000 | NC      | $-3485000.00   | -0.02%            |  |  |  | No            |                  2 | On Loan: No      |
| Regeneron Pharmaceuticals Inc                     | REGENERON PHARM                            | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |    316121 | NS      | $246634442.99  | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Bioventus Inc                                     | BIOVENTUS - A                              | CUSIP: 09075A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    121439 | NS      | $921722.01     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc                            | SANA BIOTECHNOLO                           | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    516164 | NS      | $2219505.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Arvinas Inc                                       | ARVINAS INC                                | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    189104 | NS      | $2379873.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| STAAR Surgical Co                                 | STAAR SURGICAL                             | CUSIP: 852312305<br>LEI: 5299006LRHI7OJ8BY308 | Long             | EC               | CORP              | US        |     97192 | NS      | $2579475.68    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Recursion Pharmaceuticals Inc                     | RECURSION PHAR-A                           | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1107145 | NS      | $5126081.35    | 0.03%             |  |  |  | No            |                  1 | On Loan: —       |
| agilon health Inc                                 | AGILON HEALTH IN                           | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    944809 | NS      | $615165.14     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| DENTSPLY SIRONA Inc                               | DENTSPLY SIRONA                            | CUSIP: 24906P109<br>LEI: 9NHEHR1SOZCYXDO8HO28 | Long             | EC               | CORP              | US        |    605956 | NS      | $6871541.04    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Bridgebio Pharma Inc                              | BRIDGEBIO PHARMA                           | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |    435436 | NS      | $31355746.36   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Enovis Corp                                       | ENOVIS CORP                                | CUSIP: 194014502<br>LEI: 635400OP2DYYYMOIYL17 | Long             | EC               | CORP              | US        |    172780 | NS      | $5230050.60    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocugen Inc                                        | OCUGEN INC                                 | CUSIP: 67577C105<br>LEI: 549300JVNUI9CXWJLR09 | Long             | EC               | CORP              | US        |    946378 | NS      | $1173508.72    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Nurix Therapeutics Inc                            | NURIX THERAPEUTI                           | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    229700 | NS      | $4061096.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| HCA Healthcare Inc                                | HCA HEALTHCARE I                           | CUSIP: 40412C101<br>LEI: 529900PH4ZGUH2MNEU89 | Long             | EC               | CORP              | US        |    497051 | NS      | $252646052.79  | 1.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Bruker Corp                                       | BRUKER CORP                                | CUSIP: 116794108<br>LEI: LEBZ6VLQ6I8XB1NHVY15 | Long             | EC               | CORP              | US        |    322685 | NS      | $15750254.85   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:AVANTOR INC USD 2026-Aug-31            | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    162000 | NC      | $-19440.00     | -0.00%            |  |  |  | No            |                  2 | On Loan: No      |
| AngioDynamics Inc                                 | ANGIODYNAMICS IN                           | CUSIP: 03475V101<br>LEI: 549300W3VKC5ZKMO8C28 | Long             | EC               | CORP              | US        |    123877 | NS      | $1536074.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BioRobotics Corp                          | PROCEPT BIOROBOT                           | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    169113 | NS      | $5357499.84    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMarin Pharmaceutical Inc                       | BIOMARIN PHARMAC                           | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |    553138 | NS      | $30937008.34   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Amylyx Pharmaceuticals Inc                        | AMYLYX PHARMACEU                           | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    248341 | NS      | $3720148.18    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc                         | EDGEWISE THERAPE                           | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    160325 | NS      | $4174863.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanguard Cmt Funds-Vanguard Market Liquidity Fund | Vanguard Market Liquidity Fund             | CUSIP: N/A<br>LEI: 1I6HV0TLSTR3A4XQ6L78       | Long             | STIV             | CORP              | US        |    249224 | NS      | $24922441.50   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                                      | ILLUMINA INC                               | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |    466027 | NS      | $61259249.15   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Aldeyra Therapeutics Inc                          | ALDEYRA THERAPEU                           | CUSIP: 01438T106<br>LEI: 529900HGKY864E4Y9014 | Long             | EC               | CORP              | US        |    157019 | NS      | $860464.12     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc                      | XERIS BIOPHARMA                            | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    488197 | NS      | $3505254.46    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                                        | BIOGEN INC                                 | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |    444977 | NS      | $81025861.93   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Merck & Co Inc                                    | MERCK & CO                                 | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |   7579786 | NS      | $794588966.38  | 3.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Ventyx Biosciences Inc                            | VENTYX BIOSCIENC                           | CUSIP: 92332V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    172893 | NS      | $1728930.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardelyx Inc                                       | ARDELYX INC                                | CUSIP: 039697107<br>LEI: 549300F542QR4SXHCY32 | Long             | EC               | CORP              | US        |    733069 | NS      | $4251800.20    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Corvus Pharmaceuticals Inc                        | CORVUS PHARMACEU                           | CUSIP: 221015100<br>LEI: 549300I3AVJ8F75NCX65 | Long             | EC               | CORP              | US        |    169071 | NS      | $1550381.07    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Organon & Co                                      | ORGANON & CO                               | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |    787682 | NS      | $6073028.22    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| National HealthCare Corp                          | NATL HEALTHCARE                            | CUSIP: 635906100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     39921 | NS      | $5440833.09    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| HealthEquity Inc                                  | HEALTHEQUITY INC                           | CUSIP: 42226A107<br>LEI: 529900LRJU1RAFQHM467 | Long             | EC               | CORP              | US        |    261683 | NS      | $27523817.94   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Azenta Inc                                        | AZENTA INC                                 | CUSIP: 114340102<br>LEI: 35ZN6X1ANPH25YN32Y17 | Long             | EC               | CORP              | US        |    124922 | NS      | $4442226.32    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Theravance Biopharma Inc                          | THERAVANCE B                               | CUSIP: G8807B106<br>LEI: 5493007VTSXP4Z6MIW52 | Long             | EC               | CORP              | US        |    115098 | NS      | $2336489.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc                    | PRAXIS PRECISION                           | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     62406 | NS      | $12260282.76   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Aura Biosciences Inc                              | AURA BIOSCIENCES                           | CUSIP: 05153U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    131758 | NS      | $869602.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Newamsterdam Pharma Co NV                         | NEWAMSTERDAM PHA                           | CUSIP: N/A<br>LEI: 984500B6549TF6E14D36       | Long             | EC               | CORP              | US        |    136890 | NS      | $5653557.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Harrow Inc                                        | HARROW INC                                 | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96157 | NS      | $4017439.46    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Akero Therapeutics Inc                            | AKERO THERAPEUTI                           | CUSIP: 00973Y108<br>LEI: 549300SI3KG74LBE2955 | Long             | EC               | CORP              | US        |    158009 | NS      | $8589369.24    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Emergent BioSolutions Inc                         | EMERGENT BIOSOLU                           | CUSIP: 29089Q105<br>LEI: 549300YW6TUOX8BE5103 | Long             | EC               | CORP              | US        |    160755 | NS      | $1795633.35    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Standard BioTools Inc                             | STANDARD BIOTOOL                           | CUSIP: 34385P108<br>LEI: 549300GX8Y96GSB6YP89 | Long             | EC               | CORP              | US        |    752958 | NS      | $1129437.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Baxter International Inc                          | BAXTER INTL INC                            | CUSIP: 071813109<br>LEI: J5OIVXX3P24RJRW5CK77 | Long             | EC               | CORP              | US        |   1559626 | NS      | $29227391.24   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Summit Therapeutics Inc                           | SUMMIT THERAPEUT                           | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    450036 | NS      | $8051144.04    | 0.04%             |  |  |  | No            |                  1 | On Loan: —       |
| RadNet Inc                                        | RADNET INC                                 | CUSIP: 750491102<br>LEI: 529900RECG94V2IZJ970 | Long             | EC               | CORP              | US        |    198227 | NS      | $16411213.33   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| GoodRx Holdings Inc                               | GOODRX HOLDIN-A                            | CUSIP: 38246G108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    261804 | NS      | $735669.24     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Sotera Health Co                                  | SOTERA HEALTH CO                           | CUSIP: 83601L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    646300 | NS      | $11297324.00   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| US Physical Therapy Inc                           | US PHYSICAL THER                           | CUSIP: 90337L108<br>LEI: 529900KL1UXQYFIOMY96 | Long             | EC               | CORP              | US        |     46336 | NS      | $3421913.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings plc                             | MEIRAGTX HOLDING                           | CUSIP: G59665102<br>LEI: 54930007YV6NYIOGFZ57 | Long             | EC               | CORP              | US        |    132477 | NS      | $1099559.10    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| SIGA Technologies Inc                             | SIGA TECH INC                              | CUSIP: 826917106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    131316 | NS      | $795774.96     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Encompass Health Corp                             | ENCOMPASS HEALTH                           | CUSIP: 29261A100<br>LEI: 549300FVRPM9DRQZRG64 | Long             | EC               | CORP              | US        |    305807 | NS      | $35540889.54   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| OraSure Technologies Inc                          | ORASURE TECH                               | CUSIP: 68554V108<br>LEI: 529900GNNJPNM4XHXQ77 | Long             | EC               | CORP              | US        |    210957 | NS      | $502077.66     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc                      | PROTAGONIST THER                           | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    150943 | NS      | $13584870.00   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Astria Therapeutics Inc                           | ASTRIA THERAPEUT                           | CUSIP: 04635X102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     94055 | NS      | $1189795.75    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Charles River Laboratories International Inc      | CHARLES RIVER LA                           | CUSIP: 159864107<br>LEI: 549300BSQ0R4UZ5KX287 | Long             | EC               | CORP              | US        |    149314 | NS      | $26598795.96   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| NeoGenomics Inc                                   | NEOGENOMICS INC                            | CUSIP: 64049M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    392627 | NS      | $4750786.70    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc                       | INSPIRE MEDICAL                            | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |     85334 | NS      | $10616402.94   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Butterfly Network Inc                             | BUTTERFLY NETWOR                           | CUSIP: 124155102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    614322 | NS      | $1904398.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Zentalis Pharmaceuticals Inc                      | ZENTALIS PHARMAC                           | CUSIP: 98943L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    137162 | NS      | $196141.66     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Perspective Therapeutics Inc                      | PERSPECTIVE THER                           | CUSIP: 46489V302<br>LEI: 5493005LRKM6BCABC605 | Long             | EC               | CORP              | US        |    193416 | NS      | $454527.60     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharmaceuticals Inc                         | MIRUM PHARMACEUT                           | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |    114230 | NS      | $8344501.50    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Teleflex Inc                                      | TELEFLEX INC                               | CUSIP: 879369106<br>LEI: UUL85LWXB4NGSWWXIQ25 | Long             | EC               | CORP              | US        |    134064 | NS      | $15339602.88   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| New Issuer: BB Company ID:69588108                | GUARDIAN PHARM-A                           | CUSIP: 40145W101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     60349 | NS      | $1767018.72    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant Inc                                    | IMMUNOVANT INC                             | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    211394 | NS      | $5105165.10    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceutical Inc                     | ULTRAGENYX PHARM                           | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |    262989 | NS      | $9138867.75    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc                    | DAY ONE BIOPHARM                           | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    217287 | NS      | $2062053.63    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc                            | RELAY THERAPEUTI                           | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    369578 | NS      | $2927057.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Maravai LifeSciences Holdings Inc                 | MARAVAI LIFESC-A                           | CUSIP: 56600D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    328786 | NS      | $1190205.32    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Community Health Systems Inc                      | COMMUNITY HEALTH                           | CUSIP: 203668108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    385741 | NS      | $1334663.86    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| XOMA Royalty Corp                                 | XOMA ROYALTY COR                           | CUSIP: 98419J206<br>LEI: 549300U6ZVYFCWNBJ613 | Long             | EC               | CORP              | US        |     29231 | NS      | $939192.03     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Allogene Therapeutics Inc                         | ALLOGENE THERAPE                           | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    488193 | NS      | $712761.78     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc                                  | 10X GENOMICS I-A                           | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |    312102 | NS      | $5870638.62    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Erasca Inc                                        | ERASCA INC                                 | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    522544 | NS      | $1656464.48    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MBX Biosciences Inc                               | MBX BIOSCIENCES                            | CUSIP: 55287L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     67645 | NS      | $2333076.05    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Esperion Therapeutics Inc                         | ESPERION THERAPE                           | CUSIP: 29664W105<br>LEI: 549300OFU56UKEWVUS92 | Long             | EC               | CORP              | US        |    700958 | NS      | $2810841.58    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcutis Biotherapeutics Inc                       | ARCUTIS BIOTHERA                           | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    327729 | NS      | $10044893.85   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Indivior PLC                                      | INDIVIOR PLC                               | CUSIP: N/A<br>LEI: 213800V3NCQTY7IED471       | Long             | EC               | CORP              | US        |    265913 | NS      | $8934676.80    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc                                        | PFIZER INC                                 | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |  17254286 | NS      | $444125321.64  | 2.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Akebia Therapeutics Inc                           | AKEBIA THERAPEUT                           | CUSIP: 00972D105<br>LEI: 549300CBQEHMKEEGNX42 | Long             | EC               | CORP              | US        |    763489 | NS      | $1206312.62    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Aveanna Healthcare Holdings Inc                   | AVEANNA HEALTHCA                           | CUSIP: 05356F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    157894 | NS      | $1474729.96    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Enhabit Inc                                       | ENHABIT INC                                | CUSIP: 29332G102<br>LEI: 549300RFQ78SLDFSHF49 | Long             | EC               | CORP              | US        |    131685 | NS      | $1177263.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| LivaNova PLC                                      | LIVANOVA PLC                               | CUSIP: G5509L101<br>LEI: 2138001K2FX6SHK2B339 | Long             | EC               | CORP              | US        |    165879 | NS      | $10584738.99   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Artivion Inc                                      | ARTIVION INC                               | CUSIP: 228903100<br>LEI: 549300YTKV8DMSMG6K81 | Long             | EC               | CORP              | US        |    121492 | NS      | $5668816.72    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ACADIA Pharmaceuticals Inc                        | ACADIA PHARMACEU                           | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |    358020 | NS      | $8964820.80    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| ANI Pharmaceuticals Inc                           | ANI PHARMACEUTIC                           | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |     54031 | NS      | $4584530.35    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Ensign Group Inc/The                              | ENSIGN GROUP INC                           | CUSIP: 29358P101<br>LEI: 5493003K4HEEA8Q0BC72 | Long             | EC               | CORP              | US        |    175199 | NS      | $32506422.46   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Mesa Laboratories Inc                             | MESA LABS                                  | CUSIP: 59064R109<br>LEI: 549300ZCG738WLX8ZW79 | Long             | EC               | CORP              | US        |     16698 | NS      | $1339179.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Editas Medicine Inc                               | EDITAS MEDICINE                            | CUSIP: 28106W103<br>LEI: 5299000AON4Q9NT2JE42 | Long             | EC               | CORP              | US        |    272377 | NS      | $656428.57     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Elevance Health Inc                               | ELEVANCE HEALTH                            | CUSIP: 036752103<br>LEI: 8MYN82XMYQH89CTMTH67 | Long             | EC               | CORP              | US        |    683361 | NS      | $231153691.86  | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Revvity Inc                                       | REVVITY INC                                | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |    351921 | NS      | $36744071.61   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanda Pharmaceuticals Inc                         | VANDA PHARMACEUT                           | CUSIP: 921659108<br>LEI: 529900AY8VOOQBKJ0O70 | Long             | EC               | CORP              | US        |    169808 | NS      | $910170.88     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| 4D Molecular Therapeutics Inc                     | 4D MOLECULAR THE                           | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    106149 | NS      | $1237697.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| LifeStance Health Group Inc                       | LIFESTANCE HEALT                           | CUSIP: 53228F101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    530040 | NS      | $3445260.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC - 12.5                          | CUSIP: 68218J202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22076 | NS      | $0.22          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| AnaptysBio Inc                                    | ANAPTYSBIO INC                             | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |     42444 | NS      | $1767792.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp                         | SCHOLAR ROCK HOL                           | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |    189437 | NS      | $8346594.22    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Tarsus Pharmaceuticals Inc                        | TARSUS PHARMACEU                           | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95969 | NS      | $7673681.24    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolent Health Inc                                | EVOLENT HEALTH-A                           | CUSIP: 30050B101<br>LEI: 549300CZOCFHQ2BBTR11 | Long             | EC               | CORP              | US        |    302641 | NS      | $1271092.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Lantheus Holdings Inc                             | LANTHEUS HOLDING                           | CUSIP: 516544103<br>LEI: 5299005HUB5IOJGO7S39 | Long             | EC               | CORP              | US        |    206108 | NS      | $12133577.96   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Verastem Inc                                      | VERASTEM INC                               | CUSIP: 92337C203<br>LEI: 549300IY0EFBIU8NQC81 | Long             | EC               | CORP              | US        |    130403 | NS      | $1387487.92    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Amphastar Pharmaceuticals Inc                     | AMPHASTAR PHARMA                           | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |    112550 | NS      | $3117635.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc                      | CATALYST PHARMAC                           | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |    353429 | NS      | $8273772.89    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Medical Inc                                | GLOBUS MEDICAL I                           | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |    241982 | NS      | $22030041.28   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Fate Therapeutics Inc                             | FATE THERAPEUTIC                           | CUSIP: 31189P102<br>LEI: 549300L14Q4UHOODLA90 | Long             | EC               | CORP              | US        |    297267 | NS      | $338884.38     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Teladoc Health Inc                                | TELADOC HEALTH I                           | CUSIP: 87918A105<br>LEI: 549300I2PVFBC9MFAC61 | Long             | EC               | CORP              | US        |    536671 | NS      | $4073332.89    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc                               | REPLIMUNE GROUP                            | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |    141926 | NS      | $1419260.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                                      | VERACYTE INC                               | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |    239122 | NS      | $11320035.48   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc                            | STOKE THERAPEUTI                           | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |    116534 | NS      | $3602065.94    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Henry Schein Inc                                  | HENRY SCHEIN INC                           | CUSIP: 806407102<br>LEI: VGO3WGL8H45T73F4RR92 | Long             | EC               | CORP              | US        |    331568 | NS      | $24725025.76   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Avanos Medical Inc                                | AVANOS MEDICAL I                           | CUSIP: 05350V106<br>LEI: 549300YCXWOM7NEWMQ58 | Long             | EC               | CORP              | US        |    141973 | NS      | $1666763.02    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Taysha Gene Therapies Inc                         | TAYSHA GENE THER                           | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    413625 | NS      | $1960582.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Crinetics Pharmaceuticals Inc                     | CRINETICS PHARMA                           | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |    271230 | NS      | $12357238.80   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Pliant Therapeutics Inc                           | PLIANT THERAPEUT                           | CUSIP: 729139105<br>LEI: 5493002Q5LITR7VHZH02 | Long             | EC               | CORP              | US        |    116281 | NS      | $187212.41     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corp                                       | INCYTE CORP                                | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |    503727 | NS      | $52619322.42   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| CryoPort Inc                                      | CRYOPORT                                   | CUSIP: 229050307<br>LEI: 9845004D8538BT8JF626 | Long             | EC               | CORP              | US        |    144129 | NS      | $1386520.98    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals Inc                         | IONIS PHARMACEUT                           | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |    459364 | NS      | $38003183.72   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                                      | BIOHAVEN LTD                               | CUSIP: G1110E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    352591 | NS      | $3536487.73    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech Inc                               | KRYSTAL BIOTECH                            | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |     65891 | NS      | $14364238.00   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Organogenesis Holdings Inc                        | ORGANOGENESIS HO                           | CUSIP: 68621F102<br>LEI: 549300RLC2O821TU6941 | Long             | EC               | CORP              | US        |    192122 | NS      | $995191.96     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ceribell Inc                                      | CERIBELL INC                               | CUSIP: 15678C102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     55389 | NS      | $939951.33     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvation Bio Inc                                  | NUVATION BIO INC                           | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    672305 | NS      | $5398609.15    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc                        | NEUROCRINE BIOSC                           | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |    301075 | NS      | $45811572.00   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC                          | JAZZ PHARMACEUTI                           | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | US        |    165809 | NS      | $29270262.77   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| New Issuer: BB Company ID:54419104                | HINGE HEALTH-A                             | CUSIP: 433313103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49430 | NS      | $2417621.30    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ARS Pharmaceuticals Inc                           | ARS PHARMACEUTIC                           | CUSIP: 82835W108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    164599 | NS      | $1570274.46    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanguard Cmt Funds-Vanguard Market Liquidity Fund | Vanguard Market Liquidity Fund             | CUSIP: N/A<br>LEI: 1I6HV0TLSTR3A4XQ6L78       | Long             | STIV             | CORP              | US        | 781095326 | NS      | $781095326.10  | 3.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Boston Scientific Corp                            | BOSTON SCIENTIFC                           | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |   4496517 | NS      | $456756196.86  | 2.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                                    | ELI LILLY & CO                             | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |   2441267 | NS      | $2625509420.49 | 12.89%            |  |  |  | No            |                  1 | On Loan: No      |
| Elanco Animal Health Inc                          | ELANCO ANIMAL HE                           | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |   1508657 | NS      | $35106448.39   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Tactile Systems Technology Inc                    | TACTILE SYSTEMS                            | CUSIP: 87357P100<br>LEI: 54930069VDTITHOTKJ98 | Long             | EC               | CORP              | US        |     67322 | NS      | $1730848.62    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Avadel Pharmaceuticals PLC                        | AVADEL PHARMACEU                           | CUSIP: G29687103<br>LEI: 549300E27PTSG2RHC762 | Long             | EC               | CORP              | US        |    265492 | NS      | $5705423.08    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| MaxCyte Inc                                       | MAXCYTE INC                                | CUSIP: 57777K106<br>LEI: 54930053YHXULRFCU991 | Long             | EC               | CORP              | US        |    306748 | NS      | $539876.48     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Tempus AI Inc                                     | TEMPUS AI INC                              | CUSIP: 88023B103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    281287 | NS      | $21920695.91   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Heron Therapeutics Inc                            | HERON THERAPEUTI                           | CUSIP: 427746102<br>LEI: 549300DR2I1DOPD2IX53 | Long             | EC               | CORP              | US        |    421984 | NS      | $489501.44     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc                          | ENLIVEN THERAPEU                           | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     99248 | NS      | $2143756.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Abbott Laboratories                               | ABBOTT LABS                                | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |   5281498 | NS      | $680785092.20  | 3.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics Inc                            | ORUKA THERAPEUTI                           | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |     65897 | NS      | $1983499.70    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Owens & Minor Inc                                 | OWENS & MINOR                              | CUSIP: 690732102<br>LEI: 549300LMT5KQQXCEZ733 | Long             | EC               | CORP              | US        |    234526 | NS      | $637910.72     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| QuidelOrtho Corp                                  | QUIDELORTHO CORP                           | CUSIP: 219798105<br>LEI: 549300YU8CMO9HF53113 | Long             | EC               | CORP              | US        |    206632 | NS      | $5651385.20    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Myriad Genetics Inc                               | MYRIAD GENETICS                            | CUSIP: 62855J104<br>LEI: 52990044IHUOUMETT163 | Long             | EC               | CORP              | US        |    279318 | NS      | $2131196.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Addus HomeCare Corp                               | ADDUS HOMECARE                             | CUSIP: 006739106<br>LEI: 52990090ZT33AKPDBX62 | Long             | EC               | CORP              | US        |     56081 | NS      | $6740936.20    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ChromaDex Corp                                    | NIAGEN BIOSCIENC                           | CUSIP: 171077407<br>LEI: 529900OPI7B8JPXCVS70 | Long             | EC               | CORP              | US        |    173261 | NS      | $1172976.97    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc                            | SPYRE THERAPEUTI                           | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |    148406 | NS      | $4452180.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CareDx Inc                                        | CAREDX INC                                 | CUSIP: 14167L103<br>LEI: 549300NQOFKL9NON0U06 | Long             | EC               | CORP              | US        |    153233 | NS      | $2738273.71    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc                        | RHYTHM PHARMACEU                           | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |    171166 | NS      | $18672498.94   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcus Biosciences Inc                             | ARCUS BIOSCIENCE                           | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    258414 | NS      | $6744605.40    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolus Inc                                        | EVOLUS INC                                 | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |    145626 | NS      | $1042682.16    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Madrigal Pharmaceuticals Inc                      | MADRIGAL PHARMAC                           | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |     44012 | NS      | $26274283.76   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| CorVel Corp                                       | CORVEL CORP                                | CUSIP: 221006109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     93577 | NS      | $6847964.86    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| UroGen Pharma Ltd                                 | UROGEN PHARMA LT                           | CUSIP: M96088105<br>LEI: 549300C0YCX7CG2G5D50 | Long             | EC               | CORP              | US        |    119046 | NS      | $3429715.26    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC                                 | CUSIP: 68218J103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    261520 | NS      | $473351.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Pulse Biosciences Inc                             | PULSE BIOSCIENCE                           | CUSIP: 74587B101<br>LEI: 529900NJUBI06118FM73 | Long             | EC               | CORP              | US        |     61502 | NS      | $841962.38     | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Fulcrum Therapeutics Inc                          | FULCRUM THERAPEU                           | CUSIP: 359616109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    114557 | NS      | $1253253.58    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Collegium Pharmaceutical Inc                      | COLLEGIUM PHARMA                           | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |     95451 | NS      | $4455652.68    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Tandem Diabetes Care Inc                          | TANDEM DIABETES                            | CUSIP: 875372203<br>LEI: 549300JEPFOD0K4D3I05 | Long             | EC               | CORP              | US        |    205796 | NS      | $4323773.96    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Tyra Biosciences Inc                              | TYRA BIOSCIENCES                           | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     40580 | NS      | $915484.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Kestra Medical Technologies In                    | KESTRA MEDICAL T                           | CUSIP: G52441105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     62239 | NS      | $1679208.22    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc                            | INTUITIVE SURGIC                           | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |   1087836 | NS      | $623852189.28  | 3.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Dexcom Inc                                        | DEXCOM                                     | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |   1190158 | NS      | $75539328.26   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| iRadimed Corp                                     | IRADIMED CORP                              | CUSIP: 46266A109<br>LEI: 549300YVHWP0YJ1YW816 | Long             | EC               | CORP              | US        |     25169 | NS      | $2346254.18    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Trevi Therapeutics Inc                            | TREVI THERAPEUTI                           | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    257984 | NS      | $3402808.96    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                                  | CYTOKINETICS INC                           | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |    344826 | NS      | $23492995.38   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Zoetis Inc                                        | ZOETIS INC                                 | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |   1343733 | NS      | $172239695.94  | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| PACS Group Inc                                    | PACS GROUP INC                             | CUSIP: 69380Q107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    140532 | NS      | $4695174.12    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics Inc                       | IOVANCE BIOTHERA                           | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |    932163 | NS      | $2302442.61    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Prestige Consumer Healthcare Inc                  | PRESTIGE CONSUME                           | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    149251 | NS      | $8887897.05    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Alector Inc                                       | ALECTOR INC                                | CUSIP: 014442107<br>LEI: 549300Z8RQOIY1JMHC25 | Long             | EC               | CORP              | US        |    243147 | NS      | $323385.51     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Tenet Healthcare Corp                             | TENET HEALTHCARE                           | CUSIP: 88033G407<br>LEI: 0W9AIBT6U6ADJ2I8HK17 | Long             | EC               | CORP              | US        |    268141 | NS      | $58143694.44   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc                          | AGILENT TECH INC                           | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |    860489 | NS      | $132085061.50  | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Pennant Group Inc/The                             | PENNANT GROUP-WI                           | CUSIP: 70805E109<br>LEI: 5493007H2OYR6BYLDA64 | Long             | EC               | CORP              | US        |    105496 | NS      | $2922239.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| TransMedics Group Inc                             | TRANSMEDICS GROU                           | CUSIP: 89377M109<br>LEI: 549300060GVOSMWARH50 | Long             | EC               | CORP              | US        |     98178 | NS      | $14364423.18   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| EyePoint Pharmaceuticals Inc                      | EYEPOINT PHARMAC                           | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |    188013 | NS      | $2788232.79    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcellx Inc                                       | ARCELLX INC                                | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     83859 | NS      | $6097387.89    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC Pharmaceuticals Inc                          | ORIC PHARMACEUTI                           | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |    132438 | NS      | $1573363.44    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Upstream Bio Inc                                  | UPSTREAM BIO INC                           | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     40784 | NS      | $1166422.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Inc                  | WEST PHARMACEUT                            | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |    218245 | NS      | $60508426.25   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes PLC                                      | ALKERMES PLC                               | CUSIP: G01767105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    475198 | NS      | $14056356.84   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| BrightSpring Health Services Inc                  | BRIGHTSPRING HEA                           | CUSIP: 10950A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    295552 | NS      | $10687160.32   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Gossamer Bio Inc                                  | GOSSAMER BIO INC                           | CUSIP: 38341P102<br>LEI: 549300ZOC0N2W6PSFR58 | Long             | EC               | CORP              | US        |    550597 | NS      | $1838993.98    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cidara Therapeutics Inc                           | CIDARA THERAPEUT                           | CUSIP: 171757206<br>LEI: 549300IHQ9Z7RI1X2D22 | Long             | EC               | CORP              | US        |     34548 | NS      | $7596414.24    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| McKesson Corp                                     | MCKESSON CORP                              | CUSIP: 58155Q103<br>LEI: 549300WZWOM80UCFSF54 | Long             | EC               | CORP              | US        |    377441 | NS      | $332570813.92  | 1.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Edwards Lifesciences Corp                         | EDWARDS LIFE                               | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |   1781622 | NS      | $154413178.74  | 0.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Astrana Health Inc                                | ASTRANA HEALTH I                           | CUSIP: 03763A207<br>LEI: 5493008O4R82Q4STJ936 | Long             | EC               | CORP              | US        |    136301 | NS      | $3140375.04    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vericel Corp                                      | VERICEL CORP                               | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |    153067 | NS      | $6160946.75    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Treace Medical Concepts Inc                       | TREACE MEDICAL C                           | CUSIP: 89455T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    152993 | NS      | $455919.14     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Clover Health Investments Corp                    | CLOVER HEALTH IN                           | CUSIP: 18914F103<br>LEI: 5493000HLYOYQU6LK133 | Long             | EC               | CORP              | US        |   1269552 | NS      | $3161184.48    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ADMA Biologics Inc                                | ADMA BIOLOGICS INC                         | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    723997 | NS      | $13886262.46   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC - 15                            | CUSIP: 68218J301<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22076 | NS      | $0.22          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Geron Corp                                        | GERON CORP                                 | CUSIP: 374163103<br>LEI: 549300T282D7Z2YESL90 | Long             | EC               | CORP              | US        |   1455157 | NS      | $1717085.26    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Supernus Pharmaceuticals Inc                      | SUPERNUS PHARMAC                           | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |    170774 | NS      | $7785586.66    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Zymeworks Inc                                     | ZYMEWORKS INC                              | CUSIP: 98985Y108<br>LEI: 894500AHOYAGYLYZJL67 | Long             | EC               | CORP              | US        |    113612 | NS      | $3034576.52    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| SI-BONE Inc                                       | SI-BONE INC                                | CUSIP: 825704109<br>LEI: 549300J8JGYVJJHV9C31 | Long             | EC               | CORP              | US        |    124090 | NS      | $2414791.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Humacyte Inc                                      | HUMACYTE INC                               | CUSIP: 44486Q103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    482189 | NS      | $650955.15     | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Molina Healthcare Inc                             | MOLINA HEALTHCAR                           | CUSIP: 60855R100<br>LEI: 549300NQQCEQ46YHZ591 | Long             | EC               | CORP              | US        |    164425 | NS      | $24377650.50   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Roche Holding AG                                  | ROCHE HOLDING AG - CVR (OCT 2025)          | CUSIP: N/A<br>LEI: 549300U41AUUVOAAOB37       | Long             | EC               | CORP              | CH        |       240 | NS      | $81.60         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| iRhythm Technologies Inc                          | IRHYTHM TECHNOLO                           | CUSIP: 450056106<br>LEI: 549300FJI72RJGDQS384 | Long             | EC               | CORP              | US        |     97399 | NS      | $18311985.99   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology Inc                                 | KURA ONCOLOGY IN                           | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |    223591 | NS      | $2714394.74    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| CONMED Corp                                       | CONMED CORP                                | CUSIP: 207410101<br>LEI: Z6C0YCECH9DCU5ZIQW84 | Long             | EC               | CORP              | US        |     93401 | NS      | $4055471.42    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Inc                        | VERTEX PHARM                               | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |    778040 | NS      | $337365924.40  | 1.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Danaher Corp                                      | DANAHER CORP                               | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |   1955750 | NS      | $443524985.00  | 2.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Glaukos Corp                                      | GLAUKOS CORP                               | CUSIP: 377322102<br>LEI: 5299004JA1LHE21M6T14 | Long             | EC               | CORP              | US        |    173861 | NS      | $18479685.69   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Castle Biosciences Inc                            | CASTLE BIOSCIENC                           | CUSIP: 14843C105<br>LEI: 2549007M2Q4HLR1XD252 | Long             | EC               | CORP              | US        |     88216 | NS      | $3524229.20    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Cerus Corp                                        | CERUS CORP                                 | CUSIP: 157085101<br>LEI: 254900BIEY9XIDA04Q21 | Long             | EC               | CORP              | US        |    573306 | NS      | $1009018.56    | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ImmunityBio Inc                                   | IMMUNITYBIO INC                            | CUSIP: 45256X103<br>LEI: 529900J9XLBR4HFL4B83 | Long             | EC               | CORP              | US        |   1002825 | NS      | $2366667.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Waystar Holding Corp                              | WAYSTAR HOLDING                            | CUSIP: 946784105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    347019 | NS      | $12808471.29   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc                                        | NATERA INC                                 | CUSIP: 632307104<br>LEI: 529900CQ3OZ0A0VYVU59 | Long             | EC               | CORP              | US        |    395691 | NS      | $94494967.71   | 0.46%             |  |  |  | No            |                  1 | On Loan: No      |
| AMN Healthcare Services Inc                       | AMN HEALTHCARE                             | CUSIP: 001744101<br>LEI: 529900W3ARRTCNFH2I39 | Long             | EC               | CORP              | US        |    116820 | NS      | $1945053.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Quanterix Corp                                    | QUANTERIX CORP                             | CUSIP: 74766Q101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    126638 | NS      | $919391.88     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences Inc                            | COGENT BIOSCIENC                           | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    254756 | NS      | $10246286.32   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Liquidia Corp                                     | LIQUIDIA CORP                              | CUSIP: 53635D202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    183420 | NS      | $5984994.60    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| CytomX Therapeutics Inc                           | CYTOMX THERAPEUT                           | CUSIP: 23284F105<br>LEI: 5493004VW2FW0QLL3345 | Long             | EC               | CORP              | US        |    374338 | NS      | $1602166.64    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Integer Holdings Corp                             | INTEGER HOLDINGS                           | CUSIP: 45826H109<br>LEI: 549300SUD2ED5XG6X569 | Long             | EC               | CORP              | US        |    106552 | NS      | $7690923.36    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corp                               | EXACT SCIENCES                             | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |    574540 | NS      | $58195156.60   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Brookdale Senior Living Inc                       | BROOKDALE SR                               | CUSIP: 112463104<br>LEI: LH7MQB13NWY7CJ9VC445 | Long             | EC               | CORP              | US        |    683918 | NS      | $7612007.34    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| PTC Therapeutics Inc                              | PTC THERAPEUTICS                           | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |    217043 | NS      | $18663527.57   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| MacroGenics Inc                                   | MACROGENICS INC                            | CUSIP: 556099109<br>LEI: 5493001KJQUA83L8MH79 | Long             | EC               | CORP              | US        |    156040 | NS      | $238741.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Atea Pharmaceuticals Inc                          | ATEA PHARMACEUTI                           | CUSIP: 04683R106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    156162 | NS      | $484102.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| AtriCure Inc                                      | ATRICURE INC                               | CUSIP: 04963C209<br>LEI: 254900B2I6GPHK2EXM59 | Long             | EC               | CORP              | US        |    151266 | NS      | $5463727.92    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Acadia Healthcare Co Inc                          | ACADIA HEALTHCAR                           | CUSIP: 00404A109<br>LEI: 5493005CW985Y9D0NC11 | Long             | EC               | CORP              | US        |    265879 | NS      | $4573118.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc                           | DENALI THERAPEUT                           | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |    421131 | NS      | $8199420.57    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Neumora Therapeutics Inc                          | NEUMORA THERAPEU                           | CUSIP: 640979100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    172340 | NS      | $386041.60     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals Inc                       | APELLIS PHARMACE                           | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |    230265 | NS      | $4904644.50    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Establishment Labs Holdings Inc                   | ESTABLISHMENT LA                           | CUSIP: G31249108<br>LEI: 549300BCBQ714JNJ7V58 | Long             | EC               | CORP              | US        |     52871 | NS      | $3663431.59    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Agios Pharmaceuticals Inc                         | AGIOS PHARMACEUT                           | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |    168273 | NS      | $4913571.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEXX Laboratories Inc                            | IDEXX LABS                                 | CUSIP: 45168D104<br>LEI: OGMTXK0LUU1HKV2P0J84 | Long             | EC               | CORP              | US        |    242781 | NS      | $182784959.28  | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicara Therapeutics Inc                           | BICARA THERAPEUT                           | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49654 | NS      | $921578.24     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cooper Cos Inc/The                                | COOPER COS INC                             | CUSIP: 216648501<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |    602726 | NS      | $46970437.18   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Vera Therapeutics Inc                             | VERA THERAPEUTIC                           | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    116108 | NS      | $3918645.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Privia Health Group Inc                           | PRIVIA HEALTH GR                           | CUSIP: 74276R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    298606 | NS      | $7277028.22    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardent Health Partners Inc                        | ARDENT HEALTH IN                           | CUSIP: 03980N107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     86400 | NS      | $758592.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton Dickinson & Co                             | BECTON DICKINSON                           | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |    869888 | NS      | $168775669.76  | 0.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc                       | ALNYLAM PHARMACE                           | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |    397773 | NS      | $179487110.79  | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc                         | INTELLIA THERAPE                           | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |    309146 | NS      | $2779222.54    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Multiplan Corp                                    | CLARITEV CORP                              | CUSIP: 62548M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     17454 | NS      | $943737.78     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| DocGo Inc                                         | DOCGO INC                                  | CUSIP: 256086109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    263397 | NS      | $271298.91     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Vaxcyte Inc                                       | VAXCYTE INC                                | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |    354255 | NS      | $17574590.55   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Novocure Ltd                                      | NOVOCURE LTD                               | CUSIP: G6674U108<br>LEI: 213800YPP55UMHWA4826 | Long             | EC               | CORP              | US        |    322845 | NS      | $4135644.45    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CVS Health Corp                                   | CVS HEALTH CORP                            | CUSIP: 126650100<br>LEI: 549300EJG376EN5NQE29 | Long             | EC               | CORP              | US        |   3848873 | NS      | $309295434.28  | 1.52%             |  |  |  | No            |                  1 | On Loan: No      |
| Ideaya Biosciences Inc                            | IDEAYA BIOSCIENC                           | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |    239870 | NS      | $8544169.40    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Cassava Sciences Inc                              | CASSAVA SCIENCES                           | CUSIP: 14817C107<br>LEI: 529900XA0UG5JXABYF08 | Long             | EC               | CORP              | US        |    134183 | NS      | $436094.75     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Lexicon Pharmaceuticals Inc                       | LEXICON PHARMACE                           | CUSIP: 528872302<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    552779 | NS      | $790473.97     | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Axogen Inc                                        | AXOGEN INC                                 | CUSIP: 05463X106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    139417 | NS      | $3994297.05    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Corcept Therapeutics Inc                          | CORCEPT THERA                              | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |    287522 | NS      | $22829246.80   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Mineralys Therapeutics Inc                        | MINERALYS THERAP                           | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    139171 | NS      | $6001053.52    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc                             | BEAM THERAPEUTIC                           | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    276485 | NS      | $7003365.05    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Universal Health Services Inc                     | UNIVERSAL HLTH-B                           | CUSIP: 913903100<br>LEI: 549300YGMGQDO0NMJD09 | Long             | EC               | CORP              | US        |    171171 | NS      | $41702390.73   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Janux Therapeutics Inc                            | JANUX THERAPEUTI                           | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    118989 | NS      | $4056335.01    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Celcuity Inc                                      | CELCUITY INC                               | CUSIP: 15102K100<br>LEI: 25490070W7UU7W2SEY87 | Long             | EC               | CORP              | US        |     38532 | NS      | $3897126.48    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacira BioSciences Inc                            | PACIRA BIOSCIENC                           | CUSIP: 695127100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    129350 | NS      | $3048779.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Personalis Inc                                    | PERSONALIS INC                             | CUSIP: 71535D106<br>LEI: 549300EZ2NYFK7H0US48 | Long             | EC               | CORP              | US        |    160982 | NS      | $1727336.86    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| GRAIL Inc                                         | GRAIL INC                                  | CUSIP: 384747101<br>LEI: 2549009XSNESW3VE8024 | Long             | EC               | CORP              | US        |    111316 | NS      | $12288173.24   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| HealthStream Inc                                  | HEALTHSTREAM INC                           | CUSIP: 42222N103<br>LEI: 529900OJ88H8635JNH64 | Long             | EC               | CORP              | US        |     71190 | NS      | $1790428.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                                 | VEEVA SYSTEMS-A                            | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |    472564 | NS      | $113552403.56  | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Centene Corp                                      | CENTENE CORP                               | CUSIP: 15135B101<br>LEI: 549300Z7JJ4TQSQGT333 | Long             | EC               | CORP              | US        |   1489092 | NS      | $58580879.28   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc                                     | ALTIMMUNE INC                              | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |    267468 | NS      | $1406881.68    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health Inc                               | GUARDANT HEALTH                            | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |    340735 | NS      | $36942488.70   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Viridian Therapeutics Inc                         | VIRIDIAN THERAPE                           | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |    197560 | NS      | $6314017.60    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                                       | MODERNA INC                                | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |   1065811 | NS      | $27689769.78   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Cardinal Health Inc                               | CARDINAL HEALTH                            | CUSIP: 14149Y108<br>LEI: CCU46N3GJMF4OK4N7U60 | Long             | EC               | CORP              | US        |    720939 | NS      | $153026512.14  | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Viatris Inc                                       | VIATRIS INC                                | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |   3535057 | NS      | $37789759.33   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| STERIS PLC                                        | STERIS PLC                                 | CUSIP: G8473T100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    298906 | NS      | $79592689.68   | 0.39%             |  |  |  | No            |                  1 | On Loan: No      |
| Select Medical Holdings Corp                      | SELECT MEDICAL                             | CUSIP: 81619Q105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    338126 | NS      | $5237571.74    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| RxSight Inc                                       | RXSIGHT INC                                | CUSIP: 78349D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    105435 | NS      | $1204067.70    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Omeros Corp                                       | OMEROS CORP                                | CUSIP: 682143102<br>LEI: 549300CJWLXX2MXVVV71 | Long             | EC               | CORP              | US        |    205987 | NS      | $1996014.03    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Mettler-Toledo International Inc                  | METTLER-TOLEDO                             | CUSIP: 592688105<br>LEI: 5493000BD5GJNUDIUG10 | Long             | EC               | CORP              | US        |     62524 | NS      | $92330441.28   | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Techne Corp                                   | BIO-TECHNE CORP                            | CUSIP: 09073M104<br>LEI: 54930073RLKQ51TILZ35 | Long             | EC               | CORP              | US        |    472007 | NS      | $30449171.57   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Definitive Healthcare Corp                        | DEFINITIVE HEALT                           | CUSIP: 24477E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    114255 | NS      | $324484.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ginkgo Bioworks Holdings Inc                      | GINKGO BIOWORKS                            | CUSIP: 37611X209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     99862 | NS      | $926719.36     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocular Therapeutix Inc                            | OCULAR THERAPEUT                           | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |    481965 | NS      | $5855874.75    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                                        | INSMED INC                                 | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    641450 | NS      | $133274066.50  | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Septerna Inc                                      | SEPTERNA INC                               | CUSIP: 81734D104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     33720 | NS      | $978554.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Humana Inc                                        | HUMANA INC                                 | CUSIP: 444859102<br>LEI: 529900YLDW34GJAO4J06 | Long             | EC               | CORP              | US        |    364657 | NS      | $89621750.89   | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Syndax Pharmaceuticals Inc                        | SYNDAX PHARMACEU                           | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |    249030 | NS      | $4935774.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ALX Oncology Holdings Inc                         | ALX ONCOLOGY HOL                           | CUSIP: 00166B105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     77369 | NS      | $105995.53     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| MannKind Corp                                     | MANNKIND CORP                              | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |    883521 | NS      | $4726837.35    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Fortrea Holdings Inc                              | FORTREA HOLDINGS                           | CUSIP: 34965K107<br>LEI: 5493000FIVFABOVCDU97 | Long             | EC               | CORP              | US        |    275758 | NS      | $3504884.18    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc                               | GILEAD SCIENCES                            | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |   3765307 | NS      | $473826232.88  | 2.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Travere Therapeutics Inc                          | TRAVERE THERAPEU                           | CUSIP: 89422G107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    256862 | NS      | $9095483.42    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| ICU Medical Inc                                   | ICU MEDICAL                                | CUSIP: 44930G107<br>LEI: 5493003NRW7LS2QZRH60 | Long             | EC               | CORP              | US        |     71122 | NS      | $10557349.68   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| UFP Technologies Inc                              | UFP TECHNOLOGIES                           | CUSIP: 902673102<br>LEI: 549300RJ8LY41HS70C91 | Long             | EC               | CORP              | US        |     22313 | NS      | $5058133.97    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Merus NV                                          | MERUS NV                                   | CUSIP: N5749R100<br>LEI: 549300W8GPUWU8QNU293 | Long             | EC               | CORP              | US        |    172324 | NS      | $16567229.36   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc                            | UNITEDHEALTH GRP                           | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |   2583349 | NS      | $851910999.73  | 4.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon Inc                                       | ANNEXON INC                                | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    361254 | NS      | $1625643.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Concentra Group Holdings Parent Inc               | CONCENTRA GROUP                            | CUSIP: 20603L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    351309 | NS      | $7222913.04    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Talkspace Inc                                     | TALKSPACE INC                              | CUSIP: 87427V103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    437962 | NS      | $1480311.56    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Novavax Inc                                       | NOVAVAX INC                                | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |    418438 | NS      | $2949987.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Rapport Therapeutics Inc                          | RAPPORT THERAPEU                           | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     84383 | NS      | $2507018.93    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Viking Therapeutics Inc                           | VIKING THERAPEUT                           | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    324857 | NS      | $11957986.17   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Ironwood Pharmaceuticals Inc                      | IRONWOOD PHARMAC                           | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |    442926 | NS      | $1550241.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cross Country Healthcare Inc                      | CROSS COUNTRY HE                           | CUSIP: 227483104<br>LEI: 54930037L0NBIPZ5S663 | Long             | EC               | CORP              | US        |     89381 | NS      | $917049.06     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| CorMedix Inc                                      | CORMEDIX INC                               | CUSIP: 21900C308<br>LEI: 5299006YIA3L0MBW8358 | Long             | EC               | CORP              | US        |    224384 | NS      | $2201207.04    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Repligen Corp                                     | REPLIGEN CORP                              | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |    162194 | NS      | $27738417.88   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Lyell Immunopharma Inc                            | LYELL IMMUNOPHAR                           | CUSIP: 55083R203<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23263 | NS      | $558312.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Aurinia Pharmaceuticals Inc                       | AURINIA PHARMACE                           | CUSIP: 05156V102<br>LEI: 5299008YP2BW4570ML28 | Long             | EC               | CORP              | US        |    339164 | NS      | $5467323.68    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| LeMaitre Vascular Inc                             | LEMAITRE VASCULA                           | CUSIP: 525558201<br>LEI: 549300FZUBUB7MHY8R17 | Long             | EC               | CORP              | US        |     65423 | NS      | $5426837.85    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:JOHNSON & JOHNSON USD 2027-Jan-29      | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    100000 | NC      | $734000.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Neogen Corp                                       | NEOGEN CORP                                | CUSIP: 640491106<br>LEI: 549300HJT9FC36N4UW43 | Long             | EC               | CORP              | US        |    629966 | NS      | $3767196.68    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Alphatec Holdings Inc                             | ALPHATEC HOLDING                           | CUSIP: 02081G201<br>LEI: 549300EZE8CQ8K65FS24 | Long             | EC               | CORP              | US        |    358862 | NS      | $8092338.10    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Cencora Inc                                       | CENCORA INC                                | CUSIP: 03073E105<br>LEI: AI8GXW8LG5WK7E9UD086 | Long             | EC               | CORP              | US        |    558896 | NS      | $206193501.28  | 1.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corp                                      | INSULET CORP                               | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |    213631 | NS      | $69897926.89   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Vir Biotechnology Inc                             | VIR BIOTECHNOLOG                           | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    272857 | NS      | $1751741.94    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Johnson & Johnson                                 | JOHNSON&JOHNSON                            | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |   4532188 | NS      | $937800340.96  | 4.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Merit Medical Systems Inc                         | MERIT MEDICAL                              | CUSIP: 589889104<br>LEI: 549300OYTY138SP2CE83 | Long             | EC               | CORP              | US        |    179729 | NS      | $15562734.11   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Rad Laboratories Inc                          | BIO-RAD LABS-A                             | CUSIP: 090572207<br>LEI: 549300ZC1GPV35XYDK53 | Long             | EC               | CORP              | US        |     56681 | NS      | $18413389.66   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Integra LifeSciences Holdings Corp                | INTEGRA LIFESCIE                           | CUSIP: 457985208<br>LEI: WB7IJCYY8YFTENS4O147 | Long             | EC               | CORP              | US        |    201252 | NS      | $2640426.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| OrthoPediatrics Corp                              | ORTHOPEDIATRICS                            | CUSIP: 68752L100<br>LEI: 5493000KUTPFGOPAT717 | Long             | EC               | CORP              | US        |     52960 | NS      | $979230.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Kodiak Sciences Inc                               | KODIAK SCIENCES                            | CUSIP: 50015M109<br>LEI: 254900IXI5NI8C9OQE24 | Long             | EC               | CORP              | US        |     87942 | NS      | $2020907.16    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Schrodinger Inc/United States                     | SCHRODINGER INC                            | CUSIP: 80810D103<br>LEI: 984500044BAE4791E559 | Long             | EC               | CORP              | US        |    196800 | NS      | $3455808.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics Inc                       | MONTE ROSA THERA                           | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     94051 | NS      | $1520804.67    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MoonLake Immunotherapeutics                       | MOONLAKE IMMUNOT                           | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96424 | NS      | $1323901.52    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:GLOBUS MEDICAL INC - A USD 2026-Aug-31 | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    100000 | NC      | $-14000.00     | -0.00%            |  |  |  | No            |                  2 | On Loan: No      |
| Arcturus Therapeutics Holdings Inc                | ARCTURUS THERAPE                           | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     74415 | NS      | $505277.85     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Amneal Pharmaceuticals Inc                        | AMNEAL PHARM INC                           | CUSIP: 03168L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    478084 | NS      | $5985611.68    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| REGENXBIO Inc                                     | REGENXBIO INC                              | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |    128837 | NS      | $1725127.43    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:UNITEDHEALTH GROUP INC USD 2026-Aug-31 | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    165000 | NC      | $575850.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Phathom Pharmaceuticals Inc                       | PHATHOM PHARMACE                           | CUSIP: 71722W107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    127759 | NS      | $1995595.58    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Chinook Therapeutics Inc                          | CHINOOK THERAPEUTICS INC - CVR (AUG 2023)  | CUSIP: N/A<br>LEI: 549300X0O3003W5QYQ48       | Long             | EC               | CORP              | US        |       784 | NS      | $0.00          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Quantum-Si Inc                                    | QUANTUM-SI INC                             | CUSIP: 74765K105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    497059 | NS      | $700853.19     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ArriVent Biopharma Inc                            | ARRIVENT BIOPHAR                           | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     61448 | NS      | $1409617.12    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Fulgent Genetics Inc                              | FULGENT GENETICS                           | CUSIP: 359664109<br>LEI: 549300CL6P01M68QJ404 | Long             | EC               | CORP              | US        |     60253 | NS      | $1782283.74    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Masimo Corp                                       | MASIMO CORP                                | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |    140127 | NS      | $19958288.61   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Dynavax Technologies Corp                         | DYNAVAX TECHNOLO                           | CUSIP: 268158201<br>LEI: 549300T5URIXWDILX594 | Long             | EC               | CORP              | US        |    284308 | NS      | $3232581.96    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Labcorp Holdings Inc                              | LABCORP HOLDINGS                           | CUSIP: 504922105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    251954 | NS      | $67720196.12   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION Medicines Inc                          | REVOLUTION MEDIC                           | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |    425776 | NS      | $33108341.76   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Tilray Brands Inc                                 | TILRAY BRANDS IN                           | CUSIP: 88688T100<br>LEI: 549300Y4V60733TO1478 | Long             | EC               | CORP              | US        |   3403433 | NS      | $2766991.03    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Omnicell Inc                                      | OMNICELL INC                               | CUSIP: 68213N109<br>LEI: 5493008RH0GTKHHPZI77 | Long             | EC               | CORP              | US        |    139185 | NS      | $5081644.35    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-01-27

**Name of Applicant:** VANGUARD WORLD FUND

**Signature:** Ashley Grim

**Name of Signer:** Ashley Grim

**Title:** Treasurer