# EDGAR Filing Document

**Accession Number:** 0001631574
**File Stem:** 0000902664-23-001463
**Filing Date:** 2023-2
**Character Count:** 12964
**Document Hash:** e3c2127c849e9440e21a25e9d55b6095
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000902664-23-001463.hdr.sgml**: 20230210

**ACCESSION NUMBER**: 0000902664-23-001463

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230210

**DATE AS OF CHANGE**: 20230210

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Wave Life Sciences Ltd.
- **CENTRAL INDEX KEY:** 0001631574
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** U0
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-89180
- **FILM NUMBER:** 23611764

**BUSINESS ADDRESS:**
- **STREET 1:** 7 STRAITS VIEW
- **STREET 2:** #12-00, MARINA ONE EAST TOWER
- **CITY:** SINGAPORE
- **STATE:** U0
- **ZIP:** 018936
- **BUSINESS PHONE:** 617-949-2900

**MAIL ADDRESS:**
- **STREET 1:** 733 CONCORD AVENUE
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02138

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** WAVE Life Sciences Ltd.
- **DATE OF NAME CHANGE:** 20170516

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Wave Life Sciences Ltd.
- **DATE OF NAME CHANGE:** 20151106

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Wave Life Sciences LTD.
- **DATE OF NAME CHANGE:** 20151106
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** M28 Capital Management LP
- **CENTRAL INDEX KEY:** 0001807489
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** 700 CANAL STREET, 2ND FLOOR
- **CITY:** STAMFORD
- **STATE:** CT
- **ZIP:** 06902
- **BUSINESS PHONE:** 203-516-3730

**MAIL ADDRESS:**
- **STREET 1:** 700 CANAL STREET, 2ND FLOOR
- **CITY:** STAMFORD
- **STATE:** CT
- **ZIP:** 06902

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| | |
|:---|:---|
| &nbsp;&nbsp;**SECURITIES AND EXCHANGE COMMISSION** | &nbsp;&nbsp;**SECURITIES AND EXCHANGE COMMISSION** |
| &nbsp;&nbsp;**Washington, D.C. 20549** | &nbsp;&nbsp;**Washington, D.C. 20549** |
| &nbsp;&nbsp;**SCHEDULE 13G/A** | &nbsp;&nbsp;**SCHEDULE 13G/A** |
| &nbsp;&nbsp;Under the Securities Exchange Act of 1934 | &nbsp;&nbsp;Under the Securities Exchange Act of 1934 |
| &nbsp;&nbsp;(Amendment No. 1)\* | &nbsp;&nbsp;(Amendment No. 1)\* |
| &nbsp;&nbsp; Wave Life Sciences Ltd. | &nbsp;&nbsp; Wave Life Sciences Ltd. |
| &nbsp;&nbsp;(Name of Issuer) | &nbsp;&nbsp;(Name of Issuer) |
| &nbsp;&nbsp; Ordinary Shares, no par value | &nbsp;&nbsp; Ordinary Shares, no par value |
| &nbsp;&nbsp;(Title of Class of Securities) | &nbsp;&nbsp;(Title of Class of Securities) |
| &nbsp;&nbsp; Y95308105 | &nbsp;&nbsp; Y95308105 |
| &nbsp;&nbsp;(CUSIP Number) | &nbsp;&nbsp;(CUSIP Number) |
| &nbsp;&nbsp; December 31, 2022 | &nbsp;&nbsp; December 31, 2022 |
| &nbsp;&nbsp;(Date of Event Which Requires Filing of this Statement) | &nbsp;&nbsp;(Date of Event Which Requires Filing of this Statement) |
| &nbsp;&nbsp;Check the appropriate box to designate the rule pursuant to which this Schedule is filed: | &nbsp;&nbsp;Check the appropriate box to designate the rule pursuant to which this Schedule is filed: |
| &nbsp;&nbsp;◻ | &nbsp;&nbsp;Rule 13d-1(b) |
| &nbsp;&nbsp;⌧ | &nbsp;&nbsp;Rule 13d-1(c) |
| &nbsp;&nbsp;◻ | &nbsp;&nbsp;Rule 13d-1(d) |
| &nbsp;&nbsp;(Page 1 of 6 Pages) | &nbsp;&nbsp;(Page 1 of 6 Pages) |

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______________________________

\* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 (the "Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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| | | |
|:---|:---|:---|
| **CUSIP No. Y95308105** | **13G/A** | **Page 2 of 6 Pages** |

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| | | | |
|:---|:---|:---|:---|
| **1** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> M28 Capital Management LP | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> M28 Capital Management LP | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> M28 Capital Management LP |
| **2** | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp; (a) ◻<br> (b) ◻ |
| **3** | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY |
| **4** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH: | **5** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE VOTING POWER<br> - 0 - | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE VOTING POWER<br> - 0 - |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH: | **6** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED VOTING POWER<br> 5,903,405 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED VOTING POWER<br> 5,903,405 |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH: | **7** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE DISPOSITIVE POWER<br> - 0 - | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE DISPOSITIVE POWER<br> - 0 - |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH: | **8** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED DISPOSITIVE POWER<br> 5,903,405 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED DISPOSITIVE POWER<br> 5,903,405 |
| **9** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 5,903,405 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 5,903,405 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 5,903,405 |
| **10** | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;◻ |
| **11** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.8% | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.8% | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.8% |
| **12** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> PN, IA | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> PN, IA | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> PN, IA |

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| | | |
|:---|:---|:---|
| **CUSIP No. Y95308105** | **13G/A** | **Page 3 of 6 Pages** |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 1(a).** | &nbsp;&nbsp;**NAME OF ISSUER.** |
|  | &nbsp;&nbsp;The name of the issuer is Wave Life Sciences Ltd. (the "<u>Company</u>"). |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 1(b).** | &nbsp;&nbsp;**ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:** |
|  | &nbsp;&nbsp;The Company's principal executive offices are located at 7 Straits View #12-00, Marina One East Tower, Singapore 018936. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(a).** | &nbsp;&nbsp;**NAME OF PERSON FILING:** |
|  | &nbsp;&nbsp;This statement is filed by M28 Capital Management LP (the "<u>Firm</u>" or the "<u>Reporting Person</u>"). |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(b).** | &nbsp;&nbsp;**ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:** |
|  | &nbsp;&nbsp;The address for the Firm is 700 Canal Street, 2nd Floor, Stamford, CT 06902. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(c).** | &nbsp;&nbsp;**CITIZENSHIP:** |
|  | &nbsp;&nbsp;The Firm is a Delaware limited partnership. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(d).** | &nbsp;&nbsp;**TITLE OF CLASS OF SECURITIES:** |
|  | &nbsp;&nbsp;Ordinary shares, no par value (the "<u>Ordinary Shares</u>"). |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(e).** | &nbsp;&nbsp;**CUSIP NUMBER:** |
|  | Y95308105 |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 3.** | &nbsp;&nbsp;**IF THIS STATEMENT IS FILED PURSUANT TO §§ 240.13d-1(b) OR 240.13d-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A:** |

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(a) ◻ Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o);

(b) ◻ Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c);

(c) ◻ Insurance company as defined in Section 3(a)(19) of the Act (15 U.S.C. 78c);

(d) ◻ Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

(e) ◻ Investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

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| | | |
|:---|:---|:---|
| **CUSIP No. Y95308105** | **13G/A** | **Page 4 of 6 Pages** |

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(f) ◻ Employee benefit plan or endowment fund in accordance
 with Rule 13d-1(b)(1)(ii)(F);

(g) ◻ Parent holding company or control person in accordance
 with Rule 13d-1(b)(1)(ii)(G);

(h) ◻ Savings association as defined in Section 3(b) of the Federal Deposit Insurance
 Act (12 U.S.C. 1813);

(i) ◻ Church plan that is excluded from the definition of an investment company
 under Section 3(c)(14) of the Investment Company Act (15 U.S.C. 80a-3);

(j) ◻ Non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J);

(k) ◻ Group, in accordance with Rule 13d-1(b)(1)(ii)(K).

If filing as a non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J), please <br> specify the type of institution:  

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 4.** | &nbsp;&nbsp;**OWNERSHIP**. |
|  | &nbsp;&nbsp;The information required by Items 4(a) - (c) is set forth in Rows 5 - 11 of the cover page for the Reporting Person hereto and is incorporated herein by reference for the Reporting Person. |
|  | &nbsp;&nbsp;The percentages used in this Schedule 13G/A are calculated based upon 86,900,688 Ordinary Shares outstanding as of November 1, 2022, as reported in the Issuer's Quarterly Report on Form 10-Q for the quarter ending September 30, 2022 filed with the Securities and Exchange Commission on November 10, 2022. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 5.** | &nbsp;&nbsp;**OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.** |
|  | &nbsp;&nbsp;If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following: □. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 6.** | &nbsp;&nbsp;**OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.** |
|  | &nbsp;&nbsp;Not applicable. |

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| | | |
|:---|:---|:---|
| **CUSIP No. Y95308105** | **13G/A** | **Page 5 of 6 Pages** |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 7.** | &nbsp;&nbsp;**IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.** |
|  | &nbsp;&nbsp;Not applicable. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 8.** | &nbsp;&nbsp;**IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.** |
|  | &nbsp;&nbsp;Not applicable. |

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|:---|:---|
| &nbsp;&nbsp;**Item 9.** | &nbsp;&nbsp;**NOTICE OF DISSOLUTION OF GROUP.** |
|  | &nbsp;&nbsp;Not applicable. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 10.** | &nbsp;&nbsp;**CERTIFICATION.** |
|  | &nbsp;&nbsp;The Reporting Persons hereby makes the following certification: |
|  | &nbsp;&nbsp;By signing below, the Reporting Person certifies that, to the best of his or its knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. |

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| | | |
|:---|:---|:---|
| **CUSIP No. Y95308105** | **13G/A** | **Page 6 of 6 Pages** |

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**SIGNATURES**

After reasonable inquiry and to the best of our knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

DATED: February 10, 2023

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| |
|:---|
| **M28 Capital Management LP** |
| /s/ Christopher M. Taliercio |
| Christopher M. Taliercio, President and Chief Compliance Officer |

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