# EDGAR Filing Document

**Accession Number:** 0001651308
**File Stem:** 0001042047-23-000010
**Filing Date:** 2023-2
**Character Count:** 16220
**Document Hash:** cfdfabcf42a2dae43798883900c544e9
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001042047-23-000010.hdr.sgml**: 20230210

**ACCESSION NUMBER**: 0001042047-23-000010

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230210

**DATE AS OF CHANGE**: 20230210

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** BeiGene, Ltd.
- **CENTRAL INDEX KEY:** 0001651308
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 981209416
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-89331
- **FILM NUMBER:** 23611768

**BUSINESS ADDRESS:**
- **STREET 1:** C/O MOURANT GOVERNANCE SERVICES (CAYMAN)
- **STREET 2:** 94 SOLARIS AVENUE, CAMANA BAY
- **CITY:** GRAND CAYMAN
- **STATE:** E9
- **ZIP:** KY1-1108
- **BUSINESS PHONE:** 13459494123

**MAIL ADDRESS:**
- **STREET 1:** C/O MOURANT GOVERNANCE SERVICES (CAYMAN)
- **STREET 2:** 94 SOLARIS AVENUE, CAMANA BAY
- **CITY:** GRAND CAYMAN
- **STATE:** E9
- **ZIP:** KY1-1108
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** OYLER JOHN
- **CENTRAL INDEX KEY:** 0001042047

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**MAIL ADDRESS:**
- **STREET 1:** C/O GENTA INC
- **STREET 2:** 3550 GENERAL ATOMICS CT BLDG 9
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121

---

| |
|:---|
| **UNITED STATES** |
| **SECURITIES AND EXCHANGE COMMISSION** |
| **Washington, D.C. 20549** |

---

**SCHEDULE 13G**

**Under the Securities Exchange Act of 1934**

**(Amendment No. 6)\***

**BeiGene, Ltd.**

(Name of Issuer)

**Ordinary Shares, par value $0.0001 per share**

(Title of Class of Securities)

**07725L102\*\***

(CUSIP Number)

**December 31, 2022**

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

□ Rule 13d-1(b)

□ Rule 13d-1(c)

⌧ Rule 13d-1(d)

\*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

\*\*This CUSIP applies to the American Depository Shares, each representing 13 Ordinary Shares.

------

---

| | | | | |
|:---|:---|:---|:---|:---|
| CUSIP No. 07725L102 | CUSIP No. 07725L102 | CUSIP No. 07725L102 | CUSIP No. 07725L102 | CUSIP No. 07725L102 |
| 1. | Names of Reporting Persons<br>John V. Oyler | Names of Reporting Persons<br>John V. Oyler | Names of Reporting Persons<br>John V. Oyler | Names of Reporting Persons<br>John V. Oyler |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) | (a) | □ | □ |
|  | (b) | (b) | □ | □ |
| 3. | SEC Use Only | SEC Use Only | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>United States | Citizenship or Place of Organization<br>United States | Citizenship or Place of Organization<br>United States | Citizenship or Place of Organization<br>United States |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | 5. | 5. | Sole Voting Power<br>70,026,397 (1) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | 6. | 6. | Shared Voting Power<br>0 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | 7. | 7. | Sole Dispositive Power<br>70,026,397 (1) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person With | 8. | 8. | Shared Dispositive Power<br>0 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>70,026,397 (1) | Aggregate Amount Beneficially Owned by Each Reporting Person<br>70,026,397 (1) | Aggregate Amount Beneficially Owned by Each Reporting Person<br>70,026,397 (1) | Aggregate Amount Beneficially Owned by Each Reporting Person<br>70,026,397 (1) |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) □ | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) □ | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) □ | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) □ |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.1% (2) | Percent of Class Represented by Amount in Row (9)<br>5.1% (2) | Percent of Class Represented by Amount in Row (9)<br>5.1% (2) | Percent of Class Represented by Amount in Row (9)<br>5.1% (2) |
| 12. | Type of Reporting Person (See Instructions)<br>IN | Type of Reporting Person (See Instructions)<br>IN | Type of Reporting Person (See Instructions)<br>IN | Type of Reporting Person (See Instructions)<br>IN |

---

(1)&nbsp;&nbsp;&nbsp;&nbsp; Consists of (i) 1,260,568 ordinary shares held directly by Mr. Oyler; (ii) 9,633,361 ordinary shares held for the benefit of Mr. Oyler in a Roth IRA PENSCO trust account; (iii) 102,188 ordinary shares held by The John Oyler Legacy Trust, of which Mr. Oyler's father is a trustee, for the benefit of his minor child, for which Mr. Oyler disclaims beneficial ownership; (iv) 7,727,927 ordinary shares held in a grantor retained annuity trust, of which Mr. Oyler's father is a trustee, for which Mr. Oyler disclaims beneficial ownership; (v) 29,072,476 ordinary shares held by Oyler Investment LLC, 99% of the limited liability company interest owned by a grantor retained annuity trust, of which Mr. Oyler's father is a trustee, for which Mr. Oyler disclaims beneficial ownership; (vi) 481,533 ordinary shares held by the P&O Trust, the beneficiaries of which include Mr. Oyler's minor child and others, for which Mr. Oyler disclaims beneficial ownership; (vii) 1,456,052 ordinary shares held by a private foundation of which Mr. Oyler, Victoria Pan and the other(s) serve as directors, for which Mr. Oyler disclaims beneficial ownership; and (viii) 20,292,292 shares issuable to Mr. Oyler upon exercise of share options or restricted share units exercisable or vesting within 60 days after December 31, 2022.

(2)&nbsp;&nbsp;&nbsp;&nbsp; Based on 1,356,140,180 ordinary shares outstanding as of December 31, 2022, as reported by the Issuer to the Reporting Person.

------

---

| | | |
|:---|:---|:---|
| **Item 1.** | | |
|  | (a) | Name of Issuer<br>BeiGene, Ltd. |
|  | (b) | Address of Issuer's Principal Executive Offices<br>c/o Mourant Governance Services (Cayman) Limited<br>94 Solaris Avenue, Camana Bay<br>Grand Cayman KY1-1108<br>Cayman Islands |
| **Item 2.** |  |  |
|  | (a) | Name of Person Filing<br>John V. Oyler |
|  | (b) | Address of Principal Business Office or, if none, Residence<br>c/o Mourant Governance Services (Cayman) Limited<br>94 Solaris Avenue, Camana Bay<br>Grand Cayman KY1-1108<br>Cayman Islands |
|  | (c) | Citizenship<br>United States |
|  | (d) | Title of Class of Securities<br>Ordinary Shares, par value $0.0001 per share |
|  | (e) | CUSIP Number<br>07725L102 |
| **Item 3.** | **If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:** | **If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:** |
| This statement is not filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c). | This statement is not filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c). | This statement is not filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c). |

---

------

---

| | | | |
|:---|:---|:---|:---|
| **Item 4.** | **Ownership** | **Ownership** | **Ownership** |
| Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. | Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. | Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. | Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. |
|  | (a) | Amount beneficially owned: <br>70,026,397<br>Consists of (i) 1,260,568 ordinary shares held directly by Mr. Oyler; (ii) 9,633,361 ordinary shares held for the benefit of Mr. Oyler in a Roth IRA PENSCO trust account; (iii) 102,188 ordinary shares held by The John Oyler Legacy Trust, of which Mr. Oyler's father is a trustee, for the benefit of his minor child, for which Mr. Oyler disclaims beneficial ownership; (iv) 7,727,927 ordinary shares held in a grantor retained annuity trust, of which Mr. Oyler's father is a trustee, for which Mr. Oyler disclaims beneficial ownership; (v) 29,072,476 ordinary shares held by Oyler Investment LLC, 99% of the limited liability company interest owned by a grantor retained annuity trust, of which Mr. Oyler's father is a trustee, for which Mr. Oyler disclaims beneficial ownership; (vi) 481,533 ordinary shares held by the P&O Trust, the beneficiaries of which include Mr. Oyler's minor child and others, for which Mr. Oyler disclaims beneficial ownership; (vii) 1,456,052 ordinary shares held by a private foundation of which Mr. Oyler, Victoria Pan and the other(s) serve as directors, for which Mr. Oyler disclaims beneficial ownership; and (viii) 20,292,292 shares issuable to Mr. Oyler upon exercise of share options or restricted share units exercisable or vesting within 60 days after December 31, 2022. | Amount beneficially owned: <br>70,026,397<br>Consists of (i) 1,260,568 ordinary shares held directly by Mr. Oyler; (ii) 9,633,361 ordinary shares held for the benefit of Mr. Oyler in a Roth IRA PENSCO trust account; (iii) 102,188 ordinary shares held by The John Oyler Legacy Trust, of which Mr. Oyler's father is a trustee, for the benefit of his minor child, for which Mr. Oyler disclaims beneficial ownership; (iv) 7,727,927 ordinary shares held in a grantor retained annuity trust, of which Mr. Oyler's father is a trustee, for which Mr. Oyler disclaims beneficial ownership; (v) 29,072,476 ordinary shares held by Oyler Investment LLC, 99% of the limited liability company interest owned by a grantor retained annuity trust, of which Mr. Oyler's father is a trustee, for which Mr. Oyler disclaims beneficial ownership; (vi) 481,533 ordinary shares held by the P&O Trust, the beneficiaries of which include Mr. Oyler's minor child and others, for which Mr. Oyler disclaims beneficial ownership; (vii) 1,456,052 ordinary shares held by a private foundation of which Mr. Oyler, Victoria Pan and the other(s) serve as directors, for which Mr. Oyler disclaims beneficial ownership; and (viii) 20,292,292 shares issuable to Mr. Oyler upon exercise of share options or restricted share units exercisable or vesting within 60 days after December 31, 2022. |
|  | (b) | Percent of class: <br>5.1% | Percent of class: <br>5.1% |
|  | (c) | Number of shares as to which such person has: | Number of shares as to which such person has: |
|  |  | (i) | Sole power to vote or to direct the vote:<br>See Cover Pages Items 5-9. |
|  |  | (ii) | Shared power to vote or to direct the vote:<br>See Cover Pages Items 5-9. |
|  |  | (iii) | Sole power to dispose or to direct the disposition of:<br>See Cover Pages Items 5-9. |
|  |  | (iv) | Shared power to dispose or to direct the disposition of:<br>See Cover Pages Items 5-9. |
| INSTRUCTION. For computations regarding securities which represent a right to acquire an underlying security SEE ss.240.13d3(d)(1). | INSTRUCTION. For computations regarding securities which represent a right to acquire an underlying security SEE ss.240.13d3(d)(1). | INSTRUCTION. For computations regarding securities which represent a right to acquire an underlying security SEE ss.240.13d3(d)(1). | INSTRUCTION. For computations regarding securities which represent a right to acquire an underlying security SEE ss.240.13d3(d)(1). |
| **Item 5.** | **Ownership of Five Percent or Less of a Class** | **Ownership of Five Percent or Less of a Class** | **Ownership of Five Percent or Less of a Class** |
| Not applicable. | Not applicable. | Not applicable. | Not applicable. |
| **Item 6.** | **Ownership of More than Five Percent on Behalf of Another Person** | **Ownership of More than Five Percent on Behalf of Another Person** | **Ownership of More than Five Percent on Behalf of Another Person** |
| Not applicable. | Not applicable. | Not applicable. | Not applicable. |
| **Item 7.** | **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company** | **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company** | **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company** |
| Not applicable. | Not applicable. | Not applicable. | Not applicable. |
| **Item 8.** | **Identification and Classification of Members of the Group** | **Identification and Classification of Members of the Group** | **Identification and Classification of Members of the Group** |
| Not applicable. | Not applicable. | Not applicable. | Not applicable. |
| **Item 9.** | **Notice of Dissolution of Group** | **Notice of Dissolution of Group** | **Notice of Dissolution of Group** |
| Not applicable. | Not applicable. | Not applicable. | Not applicable. |
| **Item 10.** | **Certification** | **Certification** | **Certification** |
| Not applicable. | Not applicable. | Not applicable. | Not applicable. |

---

------

**SIGNATURE**

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

---

| | | |
|:---|:---|:---|
| Date: February 10, 2023 | JOHN V. OYLER | JOHN V. OYLER |
|  | By: | /s/ John V. Oyler |
|  | Name: | John V. Oyler |

---

<br>