# EDGAR Filing Document

**Accession Number:** 0001719406
**File Stem:** 0001437749-25-028567
**Filing Date:** 2025-9
**Character Count:** 14783
**Document Hash:** 34219569c5cb261f2b0d07e1a8f32da0
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001437749-25-028567.hdr.sgml**: 20250908

**ACCESSION NUMBER**: 0001437749-25-028567

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 15

**CONFORMED PERIOD OF REPORT**: 20250902

**ITEM INFORMATION**: Other Events

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20250908

**DATE AS OF CHANGE**: 20250908

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** NRX Pharmaceuticals, Inc.
- **CENTRAL INDEX KEY:** 0001719406
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 822844431
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38302
- **FILM NUMBER:** 251300470

**BUSINESS ADDRESS:**
- **STREET 1:** 1201 ORANGE STREET
- **STREET 2:** SUITE 600
- **CITY:** WILMINGTON
- **STATE:** DE
- **ZIP:** 19801
- **BUSINESS PHONE:** 484-254-6134

**MAIL ADDRESS:**
- **STREET 1:** 1201 ORANGE STREET
- **STREET 2:** SUITE 600
- **CITY:** WILMINGTON
- **STATE:** DE
- **ZIP:** 19801

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Big Rock Partners Acquisition Corp.
- **DATE OF NAME CHANGE:** 20171012

?xml version='1.0' encoding='ASCII'? nrxp20250908_8k.htm

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**WASHINGTON, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**PURSUANT TO SECTION 13 OR 15(d) OF THE**

**SECURITIES EXCHANGE ACT OF 1934**

Date of Report (Date of earliest event reported) **September 2, 2025**

**NRX PHARMACEUTICALS, INC.**

(Exact name of registrant as specified in its charter)

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| | | |
|:---|:---|:---|
| **Delaware** | **001-38302** | **82-2844431** |
| (State or other jurisdiction<br> of incorporation) | (Commission<br> File Number) | (I.R.S. Employer<br> Identification No.) |

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**1201 Orange Street, Suite 600**

**Wilmington, Delaware 19801**

(Address of principal executive offices) (Zip Code)

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| |
|:---|
| **(484) 254-6134** |
| (Registrant's telephone number, including area code) |

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| |
|:---|
| **N/A** |
| (Former name or former address, if changed since last report.) |

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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

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| | | |
|:---|:---|:---|
| **Title of each class** | **Trading Symbol(s)** | **Name of each exchange on which**<br> **registered** |
| Common Stock, par value $0.001 per share | NRXP | The Nasdaq Stock Market LLC |
| Warrants to purchase one share of Common Stock | NRXPW | The Nasdaq Stock Market LLC |

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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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**Item 8.01 Other Events.**

On September 2, 2025, NRx Pharmaceuticals, Inc. (the "Company") issued a press release, which in part provides that the Company recently raised an aggregate total of approximately $8.8 million. The Company is filing this current report on Form 8-K to provide ministerial clarification that the aggregate total is comprised of gross proceeds raised through the Company's registered direct common stock offering announced in August 2025, as well as the utilization by the Company of its at-the-market offering program since the current fiscal quarter began on July 1, 2025, each of which include no warrants, repricing adjustments, or other variable rate features. The substantial majority of the $8.8 million in gross proceeds raised through the sale of common stock was placed with experienced biotech investors. A copy of the Press Release is furnished hereto as Exhibit 99.1. The Company will revert to reporting its gross proceeds raised under its ATM in the ordinary course via its Quarterly Reports on Form 10-Q.

The information in this Item 8.01 and in the Press Release furnished as Exhibit 99.1 to this current report shall not be deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained in this Item 8.01 and in the Press Release furnished as Exhibit 99.1 to this current report shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by the Company whether made before or after the date hereof, regardless of any general incorporation language in such filing.

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| | |
|:---|:---|
| **Item 9.01** | **Financial Statements and Exhibits.** |

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(d) Exhibits

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| | |
|:---|:---|
| **Exhibit No.** | **Description** |
| 99.1 | [Press Release, dated September 2, 2025](ex_859804.htm) |
| 104 | Cover Page Interactive Data File (formatted as Inline XBRL). |

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**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | | |
|:---|:---|:---|
|  | **NRX PHARMACEUTICALS, INC.** | **NRX PHARMACEUTICALS, INC.** |
| Date: September 8, 2025 | By: | /s/ *Jonathan Javitt* |
|  | Name: | Jonathan Javitt |
|  | Title:  | Interim Chief Executive Officer |

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## Exhibit 99.1

**Exhibit 99.1**

![nrxlogo.jpg](nrxlogo.jpg)

**NRx Pharmaceuticals, Inc. (NASDAQ:NRXP) Selected to Present at the 2025**<br> ***Global Passion Project* with Matthew Rockefeller and Rockefeller Capital**

&nbsp;&nbsp;&nbsp;&nbsp;● *NRx CEO presented plans for HOPE Therapeutics rollout in September 2025 and establishment of flagship location in Palm Beach, FL during symposium presentation with leadership from Rockefeller Capital and Matthew Rockefeller.* 

&nbsp;&nbsp;&nbsp;&nbsp;● *Company has recently raised $8.8 million capital from experienced biotech investors with no warrants, repricing, or other variable rate features.* 

&nbsp;&nbsp;&nbsp;&nbsp;● *HOPE clinics will combine treatment with neuroplastic drugs including ketamine, transcranial magnetic stimulation, and hyperbaric oxygen to treat suicidal depression, PTSD, traumatic brain injury and other forms of cognitive dysfunction.* 

&nbsp;&nbsp;&nbsp;&nbsp;● *Matthew Rockefeller is announced as joining the HOPE Therapeutics Advisory Board.* 

**SOUTHAMPTON, NY, September 2, 2025:** NRx Pharmaceuticals, Inc. (Nasdaq:NRXP), a clinical-stage biopharmaceutical company, presented two keynote talks to a gathering of leading family offices and family members sponsored by the Global Passion Project and Rockefeller Capital on August 28-30, 2025 in Southampton, NY. The Company's CEO, Prof. Jonathan Javitt, MD, MPH spoke alongside Matthew Rockefeller, Bradley Hilton and Cheryl Young of Rockefeller Capital, and representatives of leading family offices to detail plans for the Fall 2025 launch of HOPE Therapeutics clinics and a prospective unique one-week residential program targeting suicidal depression, PTSD, traumatic brain injury, and cognitive dysfunction. The HOPE residential program will be the nation's first to combine neuroplastic drugs, including ketamine, transcranial magnetic stimulation and hyperbaric oxygen therapy in a campus-like setting that adds nutritional therapy from one of the nation's leading chefs, neuroplastic-targeted outdoor activities, and supportive therapy. At the symposium, Matthew Rockefeller was announced as joining the advisory board of HOPE Therapeutics.

The presenters and attendees were comprised of members of some of America's leading legacy families. Andrea Cartier Bartzen, founder of The Global Passion Projects, took the stage to emphasize the foundation's mission of tackling global challenges, including the current crisis of suicidal depression and PTSD through collaboration and innovation. "By uniting the brightest minds in technology and science with investor and philanthropist visionaries committed to change, we are funding advancements that lead to longer, healthier, and more fulfilling lives," said Bartzen.

"We welcome Mr. Rockefeller to our advisory board," said Dr. Javitt. Seventeen years ago, I sat with the daughter of a dear friend the night before his funeral. He was one of the thousands of Americans who die from suicide every 11 minutes. I shared my belief that his death was caused by a biologic "short circuit" in his brain and was no more voluntary than death from a heart attack. Over the subsequent seventeen years scientific advances have continued to point to loss of neuroplasticity – the ability of brain cells to form, prune, and regrow new connections – as an underlying cause of severe depression, PTSD, traumatic brain injury, Parkinson's disease and other forms of cognitive dysfunction. While NRx continues to advance neuroplastic drug development, including ketamine and cycloserine, our HOPE Therapeutics subsidiary focuses on combining neuroplastic drugs with already-approved neuroplastic treatments including transcranial magnetic stimulation, hyperbaric oxygen therapy, and digital therapeutics. Individually, these treatments have demonstrated 60% or greater response rates. Unfortunately, they are rarely combined under a single umbrella in a patient-friendly manner. That's what we aim to do at HOPE Therapeutics. In combination, we aim for response of over 90%. Our combined treatment modalities will be available to patients and families this Fall at multiple locations in Florida and elsewhere."

The Company recently raised more than $8.8 million from experienced biotechnology investors in a common stock offering with no warrants, repricing adjustments, or other variable rate features.

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![nrxlogo.jpg](nrxlogo.jpg)

**About NRx Pharmaceuticals, Inc.**

NRx Pharmaceuticals, Inc. (www.nrxpharma.com), is a clinical-stage biopharmaceutical company developing therapeutics based on its NMDA platform for the treatment of central nervous system disorders, specifically suicidal depression, chronic pain, and PTSD. The Company is developing NRX-100 (preservative-free intravenous ketamine) and NRX-101, (oral D-cycloserine/lurasidone). NRX-100 has been awarded Fast Track Designation for the treatment of Suicidal ideation in Depression, including Bipolar Depression. NRX-101 has been awarded Breakthrough Therapy Designation for the treatment of suicidal bipolar depression. NRx has recently filed an Abbreviated New Drug Application (ANDA) and initiated a New Drug Application filing for NRX-100 (IV ketamine) with an application for the Commissioner's National Priority Voucher Program for the treatment of suicidal depression.

**About HOPE Therapeutics, Inc.**

HOPE Therapeutics, Inc. (<u>www.hopetherapeutics.com</u>), a subsidiary of NRx Pharmaceuticals, is a Healthcare delivery company that is building a best-in-class network of interventional psychiatry clinics to offer ketamine, transcranial magnetics stimulation (TMS), and other lifesaving therapies to patients with suicidal depression and related disorders, together with a digital therapeutic-enabled platform designed to augment and preserve the clinical benefit of NMDA-targeted drug therapy.

**Notice Regarding Forward-Looking Statements**

The information contained herein includes forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. Forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as "may," "will," "should," "would," "expect," "plan," "believe," "intend," "look forward," and other similar expressions among others. These statements relate to future events or to the Company's future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause the Company's actual results to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. The Company has reported regulatory milestones as they have been achieved but has not predicted the outcome of any future regulatory determination. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects the Company's current views with respect to future events and is subject to these and other risks, including uncertainties and assumptions relating to the Company's operations, results of operations, growth strategy, and, among other things, liquidity. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Company's most recent Annual Report on Form 10-K and other filings with the Securities and Exchange Commission. Investors and security holders are urged to read these documents free of charge on the SEC's website at <u>http://www.sec.gov</u>. Except as may be required by applicable law, the Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, whether as a result of new

information, future events or otherwise.

**For further information:**

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| | |
|:---|:---|
| **Matthew Duffy**<br> Chief Business Officer, NRx Pharmaceuticals<br> <u>mduffy@nrxpharma.com</u> | **Brian Korb**<br> Managing Partner<br> (917) 653-5122<br> <u>brian.korb@astrpartners.co</u> |

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