# EDGAR Filing Document

**Accession Number:** 0001009258
**File Stem:** 0000950159-23-000074
**Filing Date:** 2023-2
**Character Count:** 15269
**Document Hash:** 7c4fcfdbe352e09be0d73f14b5c4f019
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000950159-23-000074.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0000950159-23-000074

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230214

**DATE AS OF CHANGE**: 20230214

**EFFECTIVENESS DATE**: 20230214

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)
- **CENTRAL INDEX KEY:** 0001009258
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-05366
- **FILM NUMBER:** 23629304

**BUSINESS ADDRESS:**
- **STREET 1:** 345 PARK AVENUE SOUTH, 12TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10010
- **BUSINESS PHONE:** 2125511600

**MAIL ADDRESS:**
- **STREET 1:** 345 PARK AVENUE SOUTH, 12TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10010

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** DEERFIELD MANAGEMENT CO
- **DATE OF NAME CHANGE:** 20131114

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** DEERFIELD MANAGEMENT CO /NY
- **DATE OF NAME CHANGE:** 19981022

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2022

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** DEERFIELD MANAGEMENT COMPANY L.P. (SERIES C)<br>**Address:** 345 Park Avenue South 12th Floor<br>New York, NY 10010

**Form 13F File Number:** 028-05366

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Flynn Management LLC its general partner and James E. Flynn<br>**Title:** Managing Member<br>**Phone:** 212-551-1600

**Signature, Place, and Date of Signing:**

/s/ James E. Flynn  New York, NY  02-14-2023<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 1

**Form 13F Information Table Entry Total:** 104

**Form 13F Information Table Value Total:** $4831008336

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

| No.   | Name                 | Form 13F File Number   |
|:---|:---|:---|
|  | Flynn Management LLC | 028-11827              |

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| ABEONA THERAPEUTICS INC | COM NEW | 00289Y206 |  | 2678260 | 869565 | SH |  | DFND | 1 | 869565 | 0 | 0 |
| ACCOLADE INC | NOTE 0.500% 4/0 | 00437EAB8 |  | 73303650 | 105000000 | PRN |  | DFND | 1 | 105000000 | 0 | 0 |
| ACUTUS MED INC | COM | 005111109 |  | 3049417 | 2651667 | SH |  | DFND | 1 | 2651667 | 0 | 0 |
| ADAPTHEALTH CORP | COMMON STOCK | 00653Q102 |  | 146589287 | 7626914 | SH |  | DFND | 1 | 7626914 | 0 | 0 |
| ALECTOR INC | COM | 014442107 |  | 9739422 | 1055192 | SH |  | DFND | 1 | 1055192 | 0 | 0 |
| ALPHATEC HLDGS INC | COM NEW | 02081G201 |  | 12927869 | 1046791 | SH |  | DFND | 1 | 1046791 | 0 | 0 |
| AMEDISYS INC | COM | 023436108 |  | 94908123 | 1136080 | SH |  | DFND | 1 | 1136080 | 0 | 0 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 |  | 99506350 | 2693000 | SH |  | DFND | 1 | 2693000 | 0 | 0 |
| ANAPTYSBIO INC | COM | 032724106 |  | 36004988 | 1161826 | SH |  | DFND | 1 | 1161826 | 0 | 0 |
| ANNEXON INC | COM | 03589W102 |  | 3018830 | 583913 | SH |  | DFND | 1 | 583913 | 0 | 0 |
| APELLIS PHARMACEUTICALS INC | NOTE 3.500% 9/1 | 03753UAB2 |  | 79433341 | 51885000 | PRN |  | DFND | 1 | 51885000 | 0 | 0 |
| APOLLO ENDOSURGERY INC | COM | 03767D108 |  | 17447500 | 1750000 | SH |  | DFND | 1 | 1750000 | 0 | 0 |
| ARS PHARMACEUTICALS INC | COM | 82835W108 |  | 94494717 | 11077927 | SH |  | DFND | 1 | 11077927 | 0 | 0 |
| ALPHATEC HLDGS INC | NOTE 0.750% 8/0 | 02081GAB8 |  | 43668321 | 48050000 | PRN |  | DFND | 1 | 48050000 | 0 | 0 |
| BELLUS HEALTH INC NEW | COM NEW | 07987C204 |  | 29435820 | 3581000 | SH |  | DFND | 1 | 3581000 | 0 | 0 |
| BROOKDALE SR LIVING INC | NOTE 2.000%10/1 | 112463AC8 |  | 112249612 | 145955000 | PRN |  | DFND | 1 | 145955000 | 0 | 0 |
| BROOKDALE SR LIVING INC | COM | 112463104 |  | 34615447 | 12679651 | SH |  | DFND | 1 | 12679651 | 0 | 0 |
| BUTTERFLY NETWORK INC | *W EXP 02/12/202 | 124155110 |  | 190667 | 733333 | SH |  | DFND | 1 | 733333 | 0 | 0 |
| CABALETTA BIO INC | COM | 12674W109 |  | 4294331 | 464252 | SH |  | DFND | 1 | 464252 | 0 | 0 |
| CAREMAX INC | COM CL A | 14171W103 |  | 57892979 | 15861090 | SH |  | DFND | 1 | 15861090 | 0 | 0 |
| CAREMAX INC | *W EXP 06/08/202 | 14171W111 |  | 350650 | 672000 | SH |  | DFND | 1 | 672000 | 0 | 0 |
| CASTLE BIOSCIENCES INC | COM | 14843C105 |  | 6406058 | 272135 | SH |  | DFND | 1 | 272135 | 0 | 0 |
| CATALYST PHARMACEUTICALS INC | COM | 14888U101 |  | 109450733 | 5884448 | SH |  | DFND | 1 | 5884448 | 0 | 0 |
| CENTENE CORP DEL | COM | 15135B101 |  | 46335650 | 565000 | SH |  | DFND | 1 | 565000 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 34290948 | 2966345 | SH |  | DFND | 1 | 2966345 | 0 | 0 |
| DA32 LIFE SCNCE TEC ACQSTN C | CLASS A COM | 23312M106 |  | 15992000 | 1600000 | SH |  | DFND | 1 | 1600000 | 0 | 0 |
| DAY ONE BIOPHARMACEUTICALS I | COM | 23954D109 |  | 20745990 | 964033 | SH |  | DFND | 1 | 964033 | 0 | 0 |
| DECIPHERA PHARMACEUTICALS IN | COM | 24344T101 |  | 38503847 | 2349228 | SH |  | DFND | 1 | 2349228 | 0 | 0 |
| DENALI THERAPEUTICS INC | COM | 24823R105 |  | 22248000 | 800000 | SH |  | DFND | 1 | 800000 | 0 | 0 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 |  | 35162245 | 3933137 | SH |  | DFND | 1 | 3933137 | 0 | 0 |
| ENHABIT INC | COM | 29332G102 |  | 39427360 | 2996000 | SH |  | DFND | 1 | 2996000 | 0 | 0 |
| EUCRATES BIOMEDICAL ACQU COR | *W EXP 10/23/202 | G3141W122 |  | 18533 | 333333 | SH |  | DFND | 1 | 333333 | 0 | 0 |
| EUCRATES BIOMEDICAL ACQU COR | UNIT 10/23/2027 | G3141W114 |  | 10 | 1 | SH |  | DFND | 1 | 1 | 0 | 0 |
| EVOLUS INC | COM | 30052C107 |  | 24925690 | 3319000 | SH |  | DFND | 1 | 3319000 | 0 | 0 |
| FOGHORN THERAPEUTICS INC | COM | 344174107 |  | 4960610 | 777525 | SH |  | DFND | 1 | 777525 | 0 | 0 |
| GUARDANT HEALTH INC | NOTE 11/1 | 40131MAB5 |  | 55784615 | 89036000 | PRN |  | DFND | 1 | 89036000 | 0 | 0 |
| GLAUKOS CORP | NOTE 2.750% 6/1 | 377322AB8 |  | 312639806 | 271752000 | PRN |  | DFND | 1 | 271752000 | 0 | 0 |
| GRAYBUG VISION INC | COMMON | 38942Q103 |  | 2640857 | 5281713 | SH |  | DFND | 1 | 5281713 | 0 | 0 |
| HEALTH CATALYST INC | NOTE 2.500% 4/1 | 42225TAB3 |  | 26015100 | 30000000 | PRN |  | DFND | 1 | 30000000 | 0 | 0 |
| HILLEVAX INC | COM | 43157M102 |  | 45072310 | 2694101 | SH |  | DFND | 1 | 2694101 | 0 | 0 |
| INTERCEPT PHARMACEUTICALS IN | NOTE 3.500% 2/1 | 45845PAC2 |  | 95235195 | 98354000 | PRN |  | DFND | 1 | 98354000 | 0 | 0 |
| IDEAYA BIOSCIENCES INC | COM | 45166A102 |  | 31681721 | 1743628 | SH |  | DFND | 1 | 1743628 | 0 | 0 |
| IMMUNOGEN INC | COM | 45253H101 |  | 31537237 | 6358314 | SH |  | DFND | 1 | 6358314 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 13269637 | 664146 | SH |  | DFND | 1 | 664146 | 0 | 0 |
| INSMED INC | NOTE 1.750% 1/1 | 457669AA7 |  | 95820127 | 102700000 | PRN |  | DFND | 1 | 102700000 | 0 | 0 |
| INTERCEPT PHARMACEUTICALS IN | NOTE 3.250% 7/0 | 45845PAA6 |  | 56418464 | 57791000 | PRN |  | DFND | 1 | 57791000 | 0 | 0 |
| INVITAE CORP | NOTE 2.000% 9/0 | 46185LAB9 |  | 190842634 | 241873000 | PRN |  | DFND | 1 | 241873000 | 0 | 0 |
| IONIS PHARMACEUTICALS INC | NOTE 4/0 | 462222AD2 |  | 118341522 | 127800000 | PRN |  | DFND | 1 | 127800000 | 0 | 0 |
| IVERIC BIO INC | COM | 46583P102 |  | 73326081 | 3424852 | SH |  | DFND | 1 | 3424852 | 0 | 0 |
| KEZAR LIFE SCIENCES INC | COM | 49372L100 |  | 10067200 | 1430000 | SH |  | DFND | 1 | 1430000 | 0 | 0 |
| KRYSTAL BIOTECH INC | COM | 501147102 |  | 13863500 | 175000 | SH |  | DFND | 1 | 175000 | 0 | 0 |
| KURA ONCOLOGY INC | COM | 50127T109 |  | 29573030 | 2383000 | SH |  | DFND | 1 | 2383000 | 0 | 0 |
| LARIMAR THERAPEUTICS INC | COM | 517125100 |  | 69967804 | 16941357 | SH |  | DFND | 1 | 16941357 | 0 | 0 |
| LIVONGO HEALTH INC | NOTE 0.875% 6/0 | 539183AA1 |  | 43769000 | 50000000 | PRN |  | DFND | 1 | 50000000 | 0 | 0 |
| MEDAVAIL HOLDINGS INC | COM | 58406B103 |  | 250820 | 836626 | SH |  | DFND | 1 | 836626 | 0 | 0 |
| MEDTECH ACQUISITION CORP | UNIT 12/18/2025 | 58507N204 |  | 10 | 1 | SH |  | DFND | 1 | 1 | 0 | 0 |
| MEDTECH ACQUISITION CORP | *W EXP 12/22/202 | 58507N113 |  | 25000 | 333333 | SH |  | DFND | 1 | 333333 | 0 | 0 |
| MERUS N V | COM | N5749R100 |  | 36825376 | 2380438 | SH |  | DFND | 1 | 2380438 | 0 | 0 |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 |  | 39630533 | 2032335 | SH |  | DFND | 1 | 2032335 | 0 | 0 |
| NATERA INC | NOTE 2.250% 5/0 | 632307AB0 |  | 108055189 | 84913000 | PRN |  | DFND | 1 | 84913000 | 0 | 0 |
| NEOGENOMICS INC | NOTE 1.250% 5/0 | 64049MAA8 |  | 5471570 | 6500000 | PRN |  | DFND | 1 | 6500000 | 0 | 0 |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 |  | 180678560 | 1512714 | SH |  | DFND | 1 | 1512714 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 |  | 27034169 | 2480199 | SH |  | DFND | 1 | 2480199 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | *W EXP 11/22/202 | N62509117 |  | 80567 | 92787 | SH |  | DFND | 1 | 92787 | 0 | 0 |
| NANOSTRING TECHNOLOGIES INC | NOTE 2.625% 3/0 | 63009RAD1 |  | 56746595 | 70204000 | PRN |  | DFND | 1 | 70204000 | 0 | 0 |
| NUVALENT INC | COM | 670703107 |  | 595332695 | 19991024 | SH |  | DFND | 1 | 19991024 | 0 | 0 |
| NUVASIVE INC | NOTE 1.000% 6/0 | 670704AL9 |  | 95183765 | 96966000 | PRN |  | DFND | 1 | 96966000 | 0 | 0 |
| NUVATION BIO INC | COM CL A | 67080N101 |  | 11241331 | 5854860 | SH |  | DFND | 1 | 5854860 | 0 | 0 |
| NUVATION BIO INC | *W EXP 07/07/202 | 67080N119 |  | 24083 | 166666 | SH |  | DFND | 1 | 166666 | 0 | 0 |
| NYXOAH S A | SHS | B6S7WD106 |  | 2271757 | 455262 | SH |  | DFND | 1 | 455262 | 0 | 0 |
| THE ONCOLOGY INSTITUTE INC | *W EXP 11/15/202 | 68236X118 |  | 137625 | 1250000 | SH |  | DFND | 1 | 1250000 | 0 | 0 |
| ONCORUS INC | COM | 68236R103 |  | 642416 | 2536186 | SH |  | DFND | 1 | 2536186 | 0 | 0 |
| 1LIFE HEALTHCARE INC | NOTE 3.000% 6/1 | 68269GAB3 |  | 39151240 | 40599000 | PRN |  | DFND | 1 | 40599000 | 0 | 0 |
| ORCHARD THERAPEUTICS PLC | SPON ADS | 68570P101 |  | 1172993 | 3161707 | SH |  | DFND | 1 | 3161707 | 0 | 0 |
| OAK STR HEALTH INC | NOTE 3/1 | 67181AAB3 |  | 75994000 | 100000000 | PRN |  | DFND | 1 | 100000000 | 0 | 0 |
| OWENS  MINOR INC NEW | COM | 690732102 |  | 23025870 | 1179000 | SH |  | DFND | 1 | 1179000 | 0 | 0 |
| PACIRA BIOSCIENCES INC | COM | 695127100 |  | 11274120 | 292000 | SH |  | DFND | 1 | 292000 | 0 | 0 |
| PACIRA BIOSCIENCES INC | NOTE 0.750% 8/0 | 695127AF7 |  | 73553424 | 81600000 | PRN |  | DFND | 1 | 81600000 | 0 | 0 |
| PEAK BIO INC | *W EXP 10/26/202 | 70470P116 |  | 73406 | 362500 | SH |  | DFND | 1 | 362500 | 0 | 0 |
| PEPGEN INC | COM | 713317105 |  | 802320 | 60009 | SH |  | DFND | 1 | 60009 | 0 | 0 |
| PHREESIA INC | COM | 71944F106 |  | 44214406 | 1366329 | SH |  | DFND | 1 | 1366329 | 0 | 0 |
| PRIME MEDICINE INC | COM | 74168J101 |  | 16449134 | 885314 | SH |  | DFND | 1 | 885314 | 0 | 0 |
| PTC THERAPEUTICS INC | NOTE 1.500% 9/1 | 69366JAD3 |  | 31357440 | 32000000 | PRN |  | DFND | 1 | 32000000 | 0 | 0 |
| QUANTUM SI INC | *W EXP 06/10/202 | 74765K113 |  | 83333 | 333333 | SH |  | DFND | 1 | 333333 | 0 | 0 |
| RAIN ONCOLOGY INC | COM | 75082Q105 |  | 22370088 | 2796261 | SH |  | DFND | 1 | 2796261 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 |  | 21237602 | 891587 | SH |  | DFND | 1 | 891587 | 0 | 0 |
| ROIVANT SCIENCES LTD | *W EXP 09/30/202 | G76279119 |  | 1940000 | 1000000 | SH |  | DFND | 1 | 1000000 | 0 | 0 |
| SEMA4 HOLDINGS CORP | COM CL A | 81663L101 |  | 2650991 | 10049244 | SH |  | DFND | 1 | 10049244 | 0 | 0 |
| SENIOR CONNECT ACQUISITN COR | *W EXP 12/31/202 | 81723H116 |  | 30050 | 500000 | SH |  | DFND | 1 | 500000 | 0 | 0 |
| SIENTRA INC | COM | 82621J105 |  | 543762 | 2679950 | SH |  | DFND | 1 | 2679950 | 0 | 0 |
| SILK RD MED INC | COM | 82710M100 |  | 73812424 | 1396640 | SH |  | DFND | 1 | 1396640 | 0 | 0 |
| SINGULAR GENOMICS SYSTEMS IN | COM | 82933R100 |  | 12966251 | 6450871 | SH |  | DFND | 1 | 6450871 | 0 | 0 |
| SOMALOGIC INC | *W EXP 08/31/202 | 83444K113 |  | 48000 | 120000 | SH |  | DFND | 1 | 120000 | 0 | 0 |
| SPRINGWORKS THERAPEUTICS INC | COM | 85205L107 |  | 26868330 | 1033000 | SH |  | DFND | 1 | 1033000 | 0 | 0 |
| SAREPTA THERAPEUTICS INC | DBCV 1.500%11/1 | 803607AB6 |  | 165397613 | 88657000 | SH |  | DFND | 1 | 88657000 | 0 | 0 |
| SURROZEN INC | *W EXP 08/01/203 | 86889P117 |  | 9183 | 166666 | SH |  | DFND | 1 | 166666 | 0 | 0 |
| TABULA RASA HEALTHCARE INC | NOTE 1.750% 2/1 | 873379AA9 |  | 114624311 | 144516000 | PRN |  | DFND | 1 | 144516000 | 0 | 0 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 |  | 19412977 | 1324214 | SH |  | DFND | 1 | 1324214 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 29026102 | 2851287 | SH |  | DFND | 1 | 2851287 | 0 | 0 |
| THE ONCOLOGY INSTITUTE INC | COM | 68236X100 |  | 5544086 | 3360052 | SH |  | DFND | 1 | 3360052 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 33565000 | 700000 | SH |  | DFND | 1 | 700000 | 0 | 0 |
| VIATRIS INC | COM | 92556V106 |  | 111300000 | 10000000 | SH |  | DFND | 1 | 10000000 | 0 | 0 |
| VIGIL NEUROSCIENCE INC | COM | 92673K108 |  | 25650125 | 2052010 | SH |  | DFND | 1 | 2052010 | 0 | 0 |
| XERIS BIOPHARMA HOLDINGS INC | NOTE 5.000% 7/1 | 98422LAA5 |  | 17094600 | 18000000 | PRN |  | DFND | 1 | 18000000 | 0 | 0 |

---