# EDGAR Filing Document

**Accession Number:** 0001894562
**File Stem:** 9999999995-26-000723
**Filing Date:** 2026-3
**Character Count:** 1293
**Document Hash:** 35406d7ffab004d8ba2862565ad6b49e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**9999999995-26-000723.hdr.sgml**: 20260305

**ACCESSION NUMBER**: 9999999995-26-000723

**CONFORMED SUBMISSION TYPE**: EFFECT

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20260304

**DATE AS OF CHANGE**: 20260305

**EFFECTIVENESS DATE**: 20260304

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Prime Medicine, Inc.
- **CENTRAL INDEX KEY:** 0001894562
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** EFFECT
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-291348
- **FILM NUMBER:** 26724020

**BUSINESS ADDRESS:**
- **STREET 1:** 60 FIRST ST.
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02141
- **BUSINESS PHONE:** 617-465-0013

**MAIL ADDRESS:**
- **STREET 1:** 60 FIRST ST.
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02141

### UNITED STATES
### SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## Notice of Effectiveness

**Date:** March 4, 2026

**Accession Number:** 0001894562-26-000009

**Form Type:** POS AM

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**CIK:** 0001894562

**Company Name:** Prime Medicine, Inc.

**File Number:** 333-291348