# EDGAR Filing Document

**Accession Number:** 0000052848
**File Stem:** 0000052848-26-000418
**Filing Date:** 2026-4
**Character Count:** 145527
**Document Hash:** 8745a6e1c858b9eef30b57d07943e553
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000052848-26-000418.hdr.sgml**: 20260428

**ACCESSION NUMBER**: 0000052848-26-000418

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20260228

**FILED AS OF DATE**: 20260428

**DATE AS OF CHANGE**: 20260427

**PERIOD START**: 20260831

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** VANGUARD WORLD FUND
- **CENTRAL INDEX KEY:** 0000052848

**ORGANIZATION NAME:**
- **EIN:** 046035483
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0831

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-01027
- **FILM NUMBER:** 26902895

**BUSINESS ADDRESS:**
- **STREET 1:** PO BOX 2600
- **STREET 2:** V26
- **CITY:** VALLEY FORGE
- **STATE:** PA
- **ZIP:** 19482
- **BUSINESS PHONE:** 6106691000

**MAIL ADDRESS:**
- **STREET 1:** PO BOX 2600
- **STREET 2:** V26
- **CITY:** VALLEY FORGE
- **STATE:** PA
- **ZIP:** 19482

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VANGUARD WORLD FUNDS
- **DATE OF NAME CHANGE:** 20020402

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VANGUARD WORLD FUND INC
- **DATE OF NAME CHANGE:** 19920703

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** IVEST FUND INC
- **DATE OF NAME CHANGE:** 19850923

## Series and Classes Contracts Data

### Vanguard Health Care Index Fund (Series ID: S000004450)

| Class ID   | Class Name     | Ticker Symbol   |
|:---|:---|:---|
| C000012222 | Admiral Shares | VHCIX           |
| C000012223 | ETF Shares     | VHT             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** VANGUARD WORLD FUND

- **b. Investment Company Act file number:** 811-01027

- **c. CIK number of Registrant:** 0000052848

- **d. LEI of Registrant:** 549300MP6BT0L4Q61L10

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 100 Vanguard Boulevard

  - **City:** Malvern

  - **State:** PA

  - **Foreign country:** US

  - **Zip / Postal Code:** 19355

  - **Telephone number:** 610-669-1000

**Item A.2. Information about the Series.**

- **a. Name of Series:** VANGUARD HEALTH CARE INDEX FUND

- **b. EDGAR series identifier (if any):** S000004450

- **c. LEI of Series:** 4G9X037GNB6OUK17TK21

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-08-31

- **b. Date as of which information is reported:** 2026-02-28

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $20286093325.26

**Total Liabilities:** $18337320.95

**Net Assets:** $20267756004.31

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000012222 | -1.73%               | -0.19%               | 2.92%                |
| Class ID C000012223 | -1.73%               | -0.20%               | 2.92%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $97692935.05             | $-471948847.96                             |
| Month 2  | $43151394.45             | $-111908192.66                             |
| Month 3  | $61103316.17             | $494232112.96                              |

### Schedule of Portfolio Investments

| Name                                              | Title                                     | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)    | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| ADMA Biologics Inc                                | ADMA BIOLOGICS INC                        | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    716183 | NS      | $11150969.31   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| ALX Oncology Holdings Inc                         | ALX ONCOLOGY HOL                          | CUSIP: 00166B105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     98277 | NS      | $207364.47     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| AMN Healthcare Services Inc                       | AMN HEALTHCARE                            | CUSIP: 001744101<br>LEI: 529900W3ARRTCNFH2I39 | Long             | EC               | CORP              | US        |    115980 | NS      | $2259290.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ANI Pharmaceuticals Inc                           | ANI PHARMACEUTIC                          | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |     53650 | NS      | $3964735.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Abbott Laboratories                               | ABBOTT LABS                               | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |   5227683 | NS      | $608240917.05  | 3.00%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc                                        | ABBVIE INC                                | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |   5306133 | NS      | $1231447346.64 | 6.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Acadia Healthcare Co Inc                          | ACADIA HEALTHCAR                          | CUSIP: 00404A109<br>LEI: 5493005CW985Y9D0NC11 | Long             | EC               | CORP              | US        |    263959 | NS      | $6187198.96    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ACADIA Pharmaceuticals Inc                        | ACADIA PHARMACEU                          | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |    355103 | NS      | $8721329.68    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp                     | ADAPTIVE BIOTECH                          | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |    343681 | NS      | $5505769.62    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| AdaptHealth Corp                                  | ADAPTHEALTH CORP                          | CUSIP: 00653Q102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    285941 | NS      | $2616360.15    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Addus HomeCare Corp                               | ADDUS HOMECARE                            | CUSIP: 006739106<br>LEI: 52990090ZT33AKPDBX62 | Long             | EC               | CORP              | US        |     55206 | NS      | $5715477.18    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc                            | SPYRE THERAPEUTI                          | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |    147345 | NS      | $6337308.45    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc                          | AGILENT TECH INC                          | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |    851608 | NS      | $103368179.04  | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Agios Pharmaceuticals Inc                         | AGIOS PHARMACEUT                          | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |    165170 | NS      | $4993089.10    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| agilon health Inc                                 | AGILON HEALTH IN                          | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    938023 | NS      | $552776.95     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Akebia Therapeutics Inc                           | AKEBIA THERAPEUT                          | CUSIP: 00972D105<br>LEI: 549300CBQEHMKEEGNX42 | Long             | EC               | CORP              | US        |    757990 | NS      | $992966.90     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Aldeyra Therapeutics Inc                          | ALDEYRA THERAPEU                          | CUSIP: 01438T106<br>LEI: 529900HGKY864E4Y9014 | Long             | EC               | CORP              | US        |    155899 | NS      | $851208.54     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Alector Inc                                       | ALECTOR INC                               | CUSIP: 014442107<br>LEI: 549300Z8RQOIY1JMHC25 | Long             | EC               | CORP              | US        |    241487 | NS      | $586813.41     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc                              | ALIGN TECHNOLOGY                          | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |    206961 | NS      | $39343286.10   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Alignment Healthcare Inc                          | ALIGNMENT HEALTH                          | CUSIP: 01625V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    505262 | NS      | $9711135.64    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Allogene Therapeutics Inc                         | ALLOGENE THERAPE                          | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    452327 | NS      | $1257469.06    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc                       | ALNYLAM PHARMACE                          | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |    393742 | NS      | $131084586.64  | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Alphatec Holdings Inc                             | ALPHATEC HOLDING                          | CUSIP: 02081G201<br>LEI: 549300EZE8CQ8K65FS24 | Long             | EC               | CORP              | US        |    356280 | NS      | $4852533.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc                                     | ALTIMMUNE INC                             | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |    265544 | NS      | $1144494.64    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Alumis Inc                                        | ALUMIS INC                                | CUSIP: 022307102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    160321 | NS      | $4759930.49    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Cencora Inc                                       | CENCORA INC                               | CUSIP: 03073E105<br>LEI: AI8GXW8LG5WK7E9UD086 | Long             | EC               | CORP              | US        |    553220 | NS      | $205875290.80  | 1.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc                                         | AMGEN INC                                 | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |   1617063 | NS      | $627679174.08  | 3.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Amicus Therapeutics Inc                           | AMICUS THERAPEUT                          | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |    832387 | NS      | $11961401.19   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Amneal Pharmaceuticals Inc                        | AMNEAL PHARM INC                          | CUSIP: 03168L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    470535 | NS      | $6498088.35    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Amphastar Pharmaceuticals Inc                     | AMPHASTAR PHARMA                          | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |    111730 | NS      | $2260297.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Amylyx Pharmaceuticals Inc                        | AMYLYX PHARMACEU                          | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    246541 | NS      | $3740026.97    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| AnaptysBio Inc                                    | ANAPTYSBIO INC                            | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |     42144 | NS      | $2320027.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp                         | ANAVEX LIFE SCIE                          | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |    256023 | NS      | $1134181.89    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| AngioDynamics Inc                                 | ANGIODYNAMICS IN                          | CUSIP: 03475V101<br>LEI: 549300W3VKC5ZKMO8C28 | Long             | EC               | CORP              | US        |    122977 | NS      | $1406856.88    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon Inc                                       | ANNEXON INC                               | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    358662 | NS      | $2008507.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Elevance Health Inc                               | ELEVANCE HEALTH                           | CUSIP: 036752103<br>LEI: 8MYN82XMYQH89CTMTH67 | Long             | EC               | CORP              | US        |    665105 | NS      | $212833600.00  | 1.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals Inc                       | APELLIS PHARMACE                          | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |    226629 | NS      | $4750143.84    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Astrana Health Inc                                | ASTRANA HEALTH I                          | CUSIP: 03763A207<br>LEI: 5493008O4R82Q4STJ936 | Long             | EC               | CORP              | US        |    135321 | NS      | $2751075.93    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc                           | APOGEE THERAPEUT                          | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95791 | NS      | $6705370.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp                            | ARBUTUS BIOPHARM                          | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | US        |    432384 | NS      | $2014909.44    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcellx Inc                                       | ARCELLX INC                               | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     83134 | NS      | $9459817.86    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardelyx Inc                                       | ARDELYX INC                               | CUSIP: 039697107<br>LEI: 549300F542QR4SXHCY32 | Long             | EC               | CORP              | US        |    725779 | NS      | $4753852.45    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcus Biosciences Inc                             | ARCUS BIOSCIENCE                          | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    256039 | NS      | $5215514.43    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcutis Biotherapeutics Inc                       | ARCUTIS BIOTHERA                          | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    323616 | NS      | $8727923.52    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcturus Therapeutics Holdings Inc                | ARCTURUS THERAPE                          | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     73875 | NS      | $607991.25     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardent Health Partners Inc                        | ARDENT HEALTH IN                          | CUSIP: 03980N107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     85780 | NS      | $805474.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ArriVent Biopharma Inc                            | ARRIVENT BIOPHAR                          | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     61008 | NS      | $1401353.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Arrowhead Pharmaceuticals Inc                     | ARROWHEAD PHARMA                          | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |    373558 | NS      | $23635014.66   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                                       | ARVINAS INC                               | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    187746 | NS      | $2491389.42    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Atea Pharmaceuticals Inc                          | ATEA PHARMACEUTI                          | CUSIP: 04683R106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    155056 | NS      | $725662.08     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| AtriCure Inc                                      | ATRICURE INC                              | CUSIP: 04963C209<br>LEI: 254900B2I6GPHK2EXM59 | Long             | EC               | CORP              | US        |    148983 | NS      | $4657208.58    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Atrium Therapeutics Inc                           | ATRIUM THERAPEUT                          | CUSIP: 04965N104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     32849 | NS      | $484522.75     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Aura Biosciences Inc                              | AURA BIOSCIENCES                          | CUSIP: 05153U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    130798 | NS      | $770400.22     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Aurinia Pharmaceuticals Inc                       | AURINIA PHARMACE                          | CUSIP: 05156V102<br>LEI: 5299008YP2BW4570ML28 | Long             | EC               | CORP              | US        |    336741 | NS      | $4771619.97    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Avanos Medical Inc                                | AVANOS MEDICAL I                          | CUSIP: 05350V106<br>LEI: 549300YCXWOM7NEWMQ58 | Long             | EC               | CORP              | US        |    140953 | NS      | $1987437.30    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Avantor Inc                                       | AVANTOR INC                               | CUSIP: 05352A100<br>LEI: 5493003VM0XB4U8YD238 | Long             | EC               | CORP              | US        |   2046659 | NS      | $18522263.95   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Aveanna Healthcare Holdings Inc                   | AVEANNA HEALTHCA                          | CUSIP: 05356F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    156754 | NS      | $1153709.44    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Axogen Inc                                        | AXOGEN INC                                | CUSIP: 05463X106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    138420 | NS      | $4392066.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc                           | AXSOME THERAPEUT                          | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |    104844 | NS      | $17182883.16   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicara Therapeutics Inc                           | BICARA THERAPEUT                          | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     57294 | NS      | $961393.32     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Baxter International Inc                          | BAXTER INTL INC                           | CUSIP: 071813109<br>LEI: J5OIVXX3P24RJRW5CK77 | Long             | EC               | CORP              | US        |   1542052 | NS      | $31411599.24   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc                             | BEAM THERAPEUTIC                          | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    272615 | NS      | $7758622.90    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton Dickinson & Co                             | BECTON DICKINSON                          | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |    860982 | NS      | $151946103.36  | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Rad Laboratories Inc                          | BIO-RAD LABS-A                            | CUSIP: 090572207<br>LEI: 549300ZC1GPV35XYDK53 | Long             | EC               | CORP              | US        |     56130 | NS      | $15628837.20   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| BioCryst Pharmaceuticals Inc                      | BIOCRYST PHARM                            | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    622166 | NS      | $5443952.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMarin Pharmaceutical Inc                       | BIOMARIN PHARMAC                          | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |    547586 | NS      | $33802483.78   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| BioLife Solutions Inc                             | BIOLIFE SOLUTION                          | CUSIP: 09062W204<br>LEI: 549300G2IVCMC2TJDW72 | Long             | EC               | CORP              | US        |    123064 | NS      | $2978148.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                                        | BIOGEN INC                                | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |    440425 | NS      | $84482323.50   | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Techne Corp                                   | BIO-TECHNE CORP                           | CUSIP: 09073M104<br>LEI: 54930073RLKQ51TILZ35 | Long             | EC               | CORP              | US        |    467358 | NS      | $27574122.00   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Bioventus Inc                                     | BIOVENTUS - A                             | CUSIP: 09075A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    120559 | NS      | $1058508.02    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Boston Scientific Corp                            | BOSTON SCIENTIFC                          | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |   4450848 | NS      | $342047668.80  | 1.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Bridgebio Pharma Inc                              | BRIDGEBIO PHARMA                          | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |    430304 | NS      | $28606609.92   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| BrightSpring Health Services Inc                  | BRIGHTSPRING HEA                          | CUSIP: 10950A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    292038 | NS      | $12099134.34   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Bristol-Myers Squibb Co                           | BRISTOL-MYER SQB                          | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |   6113689 | NS      | $381310782.93  | 1.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Brookdale Senior Living Inc                       | BROOKDALE SR                              | CUSIP: 112463104<br>LEI: LH7MQB13NWY7CJ9VC445 | Long             | EC               | CORP              | US        |    678447 | NS      | $10380239.10   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Azenta Inc                                        | AZENTA INC                                | CUSIP: 114340102<br>LEI: 35ZN6X1ANPH25YN32Y17 | Long             | EC               | CORP              | US        |    123714 | NS      | $3337803.72    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Bruker Corp                                       | BRUKER CORP                               | CUSIP: 116794108<br>LEI: LEBZ6VLQ6I8XB1NHVY15 | Long             | EC               | CORP              | US        |    318752 | NS      | $12785142.72   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Butterfly Network Inc                             | BUTTERFLY NETWOR                          | CUSIP: 124155102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    609882 | NS      | $2311452.78    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cigna Group/The                                   | THE CIGNA GROUP                           | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |    801754 | NS      | $232364344.28  | 1.15%             |  |  |  | No            |                  1 | On Loan: No      |
| CVS Health Corp                                   | CVS HEALTH CORP                           | CUSIP: 126650100<br>LEI: 549300EJG376EN5NQE29 | Long             | EC               | CORP              | US        |   3809636 | NS      | $304389916.40  | 1.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Cardinal Health Inc                               | CARDINAL HEALTH                           | CUSIP: 14149Y108<br>LEI: CCU46N3GJMF4OK4N7U60 | Long             | EC               | CORP              | US        |    713648 | NS      | $163589531.04  | 0.81%             |  |  |  | No            |                  1 | On Loan: No      |
| CareDx Inc                                        | CAREDX INC                                | CUSIP: 14167L103<br>LEI: 549300NQOFKL9NON0U06 | Long             | EC               | CORP              | US        |    152135 | NS      | $2854052.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cassava Sciences Inc                              | CASSAVA SCIENCES                          | CUSIP: 14817C107<br>LEI: 529900XA0UG5JXABYF08 | Long             | EC               | CORP              | US        |    133221 | NS      | $303743.88     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Castle Biosciences Inc                            | CASTLE BIOSCIENC                          | CUSIP: 14843C105<br>LEI: 2549007M2Q4HLR1XD252 | Long             | EC               | CORP              | US        |     87576 | NS      | $2589622.32    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc                      | CATALYST PHARMAC                          | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |    348836 | NS      | $8051134.88    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Celcuity Inc                                      | CELCUITY INC                              | CUSIP: 15102K100<br>LEI: 25490070W7UU7W2SEY87 | Long             | EC               | CORP              | US        |     38252 | NS      | $4273130.92    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc                          | CELLDEX THERAPEU                          | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |    179933 | NS      | $5414183.97    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Centene Corp                                      | CENTENE CORP                              | CUSIP: 15135B101<br>LEI: 549300Z7JJ4TQSQGT333 | Long             | EC               | CORP              | US        |   1475227 | NS      | $66208187.76   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Ceribell Inc                                      | CERIBELL INC                              | CUSIP: 15678C102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     54989 | NS      | $1026644.63    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Certara Inc                                       | CERTARA INC                               | CUSIP: 15687V109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    361931 | NS      | $2562471.48    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| CG oncology Inc                                   | CG ONCOLOGY INC                           | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    128733 | NS      | $7569500.40    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Cerus Corp                                        | CERUS CORP                                | CUSIP: 157085101<br>LEI: 254900BIEY9XIDA04Q21 | Long             | EC               | CORP              | US        |    569104 | NS      | $1456906.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Charles River Laboratories International Inc      | CHARLES RIVER LA                          | CUSIP: 159864107<br>LEI: 549300BSQ0R4UZ5KX287 | Long             | EC               | CORP              | US        |    147743 | NS      | $26370648.07   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Chemed Corp                                       | CHEMED CORP                               | CUSIP: 16359R103<br>LEI: 54930020031IDJT2IM79 | Long             | EC               | CORP              | US        |     43752 | NS      | $17938757.52   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Chinook Therapeutics Inc                          | CHINOOK THERAPEUTICS INC - CVR (AUG 2023) | CUSIP: N/A<br>LEI: 549300X0O3003W5QYQ48       | Long             | EC               | CORP              | US        |       784 | NS      | $0.00          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Clover Health Investments Corp                    | CLOVER HEALTH IN                          | CUSIP: 18914F103<br>LEI: 5493000HLYOYQU6LK133 | Long             | EC               | CORP              | US        |   1260385 | NS      | $2634204.65    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences Inc                            | COGENT BIOSCIENC                          | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    251517 | NS      | $9771435.45    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Enovis Corp                                       | ENOVIS CORP                               | CUSIP: 194014502<br>LEI: 635400OP2DYYYMOIYL17 | Long             | EC               | CORP              | US        |    171267 | NS      | $4362170.49    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Collegium Pharmaceutical Inc                      | COLLEGIUM PHARMA                          | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |     94785 | NS      | $3949690.95    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Community Health Systems Inc                      | COMMUNITY HEALTH                          | CUSIP: 203668108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    382981 | NS      | $1325114.26    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Concentra Group Holdings Parent Inc               | CONCENTRA GROUP                           | CUSIP: 20603L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    346093 | NS      | $8292388.28    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| CONMED Corp                                       | CONMED CORP                               | CUSIP: 207410101<br>LEI: Z6C0YCECH9DCU5ZIQW84 | Long             | EC               | CORP              | US        |     92707 | NS      | $4264522.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Cooper Cos Inc/The                                | COOPER COS INC                            | CUSIP: 216648501<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |    597328 | NS      | $49978433.76   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Corcept Therapeutics Inc                          | CORCEPT THERA                             | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |    284729 | NS      | $10164825.30   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| CorMedix Inc                                      | CORMEDIX INC                              | CUSIP: 21900C308<br>LEI: 5299006YIA3L0MBW8358 | Long             | EC               | CORP              | US        |    222764 | NS      | $1588307.32    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| QuidelOrtho Corp                                  | QUIDELORTHO CORP                          | CUSIP: 219798105<br>LEI: 549300YU8CMO9HF53113 | Long             | EC               | CORP              | US        |    203424 | NS      | $4625861.76    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CorVel Corp                                       | CORVEL CORP                               | CUSIP: 221006109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     92188 | NS      | $4755057.04    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Corvus Pharmaceuticals Inc                        | CORVUS PHARMACEU                          | CUSIP: 221015100<br>LEI: 549300I3AVJ8F75NCX65 | Long             | EC               | CORP              | US        |    167790 | NS      | $3063845.40    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Crinetics Pharmaceuticals Inc                     | CRINETICS PHARMA                          | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |    268395 | NS      | $11031034.50   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Cross Country Healthcare Inc                      | CROSS COUNTRY HE                          | CUSIP: 227483104<br>LEI: 54930037L0NBIPZ5S663 | Long             | EC               | CORP              | US        |     88741 | NS      | $772046.70     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Artivion Inc                                      | ARTIVION INC                              | CUSIP: 228903100<br>LEI: 549300YTKV8DMSMG6K81 | Long             | EC               | CORP              | US        |    120612 | NS      | $4643562.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CryoPort Inc                                      | CRYOPORT                                  | CUSIP: 229050307<br>LEI: 9845004D8538BT8JF626 | Long             | EC               | CORP              | US        |    143089 | NS      | $1204809.38    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc                         | CULLINAN THERAPE                          | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     88832 | NS      | $1376896.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                                  | CYTOKINETICS INC                          | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |    341233 | NS      | $21231517.26   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| CytomX Therapeutics Inc                           | CYTOMX THERAPEUT                          | CUSIP: 23284F105<br>LEI: 5493004VW2FW0QLL3345 | Long             | EC               | CORP              | US        |    371652 | NS      | $1995771.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytek Biosciences Inc                             | CYTEK BIOSCIENCE                          | CUSIP: 23285D109<br>LEI: 549300K2J28BOC6FBO89 | Long             | EC               | CORP              | US        |    326812 | NS      | $1464117.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Danaher Corp                                      | DANAHER CORP                              | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |   1935699 | NS      | $407735637.36  | 2.01%             |  |  |  | No            |                  1 | On Loan: No      |
| DaVita Inc                                        | DAVITA INC                                | CUSIP: 23918K108<br>LEI: M2XHYMU3TZNEZURC6H66 | Long             | EC               | CORP              | US        |    118260 | NS      | $18484038.00   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc                    | DAY ONE BIOPHARM                          | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    215744 | NS      | $2286886.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Definitive Healthcare Corp                        | DEFINITIVE HEALT                          | CUSIP: 24477E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113455 | NS      | $145222.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Definium Therapeutics Inc                         | DEFINIUM THERAPE                          | CUSIP: 24477V105<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | US        |    240768 | NS      | $4201401.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc                           | DENALI THERAPEUT                          | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |    417443 | NS      | $8841442.74    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| DENTSPLY SIRONA Inc                               | DENTSPLY SIRONA                           | CUSIP: 24906P109<br>LEI: 9NHEHR1SOZCYXDO8HO28 | Long             | EC               | CORP              | US        |    597212 | NS      | $8767072.16    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Dexcom Inc                                        | DEXCOM                                    | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |   1177985 | NS      | $86499438.55   | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc                         | DIANTHUS THERAPE                          | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |     47904 | NS      | $2643821.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Disc Medicine Inc                                 | DISC MEDICINE IN                          | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     73237 | NS      | $4879048.94    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| DocGo Inc                                         | DOCGO INC                                 | CUSIP: 256086109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    261491 | NS      | $187750.54     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                                      | DOXIMITY INC-A                            | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    368273 | NS      | $9033736.69    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Dyne Therapeutics Inc                             | DYNE THERAPEUTIC                          | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    337675 | NS      | $5274483.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc                         | EDGEWISE THERAPE                          | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    158765 | NS      | $4832806.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Editas Medicine Inc                               | EDITAS MEDICINE                           | CUSIP: 28106W103<br>LEI: 5299000AON4Q9NT2JE42 | Long             | EC               | CORP              | US        |    270431 | NS      | $594948.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Edwards Lifesciences Corp                         | EDWARDS LIFE                              | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |   1763533 | NS      | $152492698.51  | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Roche Holding AG                                  | ROCHE HOLDING AG - CVR (OCT 2025)         | CUSIP: N/A<br>LEI: 549300U41AUUVOAAOB37       | Long             | EC               | CORP              | CH        |       240 | NS      | $81.60         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Elanco Animal Health Inc                          | ELANCO ANIMAL HE                          | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |   1493291 | NS      | $39422882.40   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Embecta Corp                                      | EMBECTA CORP                              | CUSIP: 29082K105<br>LEI: 549300RPG8GXVDHNXZ62 | Long             | EC               | CORP              | US        |    167680 | NS      | $1720396.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Emergent BioSolutions Inc                         | EMERGENT BIOSOLU                          | CUSIP: 29089Q105<br>LEI: 549300YW6TUOX8BE5103 | Long             | EC               | CORP              | US        |    159609 | NS      | $1300813.35    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Encompass Health Corp                             | ENCOMPASS HEALTH                          | CUSIP: 29261A100<br>LEI: 549300FVRPM9DRQZRG64 | Long             | EC               | CORP              | US        |    302545 | NS      | $32638554.60   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Enhabit Inc                                       | ENHABIT INC                               | CUSIP: 29332G102<br>LEI: 549300RFQ78SLDFSHF49 | Long             | EC               | CORP              | US        |    130745 | NS      | $1779439.45    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc                          | ENLIVEN THERAPEU                          | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     98572 | NS      | $2926602.68    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ensign Group Inc/The                              | ENSIGN GROUP INC                          | CUSIP: 29358P101<br>LEI: 5493003K4HEEA8Q0BC72 | Long             | EC               | CORP              | US        |    173281 | NS      | $37111591.77   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Entrada Therapeutics Inc                          | ENTRADA THERAPEU                          | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     57598 | NS      | $687144.14     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Envista Holdings Corp                             | ENVISTA HOLDINGS                          | CUSIP: 29415F104<br>LEI: 549300BX623VURJZ5269 | Long             | EC               | CORP              | US        |    498576 | NS      | $14563404.96   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Erasca Inc                                        | ERASCA INC                                | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    510649 | NS      | $6975465.34    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Esperion Therapeutics Inc                         | ESPERION THERAPE                          | CUSIP: 29664W105<br>LEI: 549300OFU56UKEWVUS92 | Long             | EC               | CORP              | US        |    695906 | NS      | $2331285.10    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolent Health Inc                                | EVOLENT HEALTH-A                          | CUSIP: 30050B101<br>LEI: 549300CZOCFHQ2BBTR11 | Long             | EC               | CORP              | US        |    300475 | NS      | $976543.75     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolus Inc                                        | EVOLUS INC                                | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |    144566 | NS      | $621633.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corp                               | EXACT SCIENCES                            | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |    568700 | NS      | $58792206.00   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Exelixis Inc                                      | EXELIXIS INC                              | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |    767891 | NS      | $33833277.46   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| EyePoint Inc                                      | EYEPOINT INC                              | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |    186653 | NS      | $3277626.68    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Fate Therapeutics Inc                             | FATE THERAPEUTIC                          | CUSIP: 31189P102<br>LEI: 549300L14Q4UHOODLA90 | Long             | EC               | CORP              | US        |    295141 | NS      | $436808.68     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Standard BioTools Inc                             | STANDARD BIOTOOL                          | CUSIP: 34385P108<br>LEI: 549300GX8Y96GSB6YP89 | Long             | EC               | CORP              | US        |    747537 | NS      | $844716.81     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Fortrea Holdings Inc                              | FORTREA HOLDINGS                          | CUSIP: 34965K107<br>LEI: 5493000FIVFABOVCDU97 | Long             | EC               | CORP              | US        |    273797 | NS      | $2935103.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| 4D Molecular Therapeutics Inc                     | 4D MOLECULAR THE                          | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    105389 | NS      | $1018057.74    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Fulcrum Therapeutics Inc                          | FULCRUM THERAPEU                          | CUSIP: 359616109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113751 | NS      | $953233.38     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Fulgent Genetics Inc                              | FULGENT GENETICS                          | CUSIP: 359664109<br>LEI: 549300CL6P01M68QJ404 | Long             | EC               | CORP              | US        |     59813 | NS      | $916933.29     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| GE HealthCare Technologies Inc                    | GE HEALTHCARE TE                          | CUSIP: 36266G107<br>LEI: 549300OI9J7XOWZMUN85 | Long             | EC               | CORP              | US        |   1371594 | NS      | $115584226.38  | 0.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Geron Corp                                        | GERON CORP                                | CUSIP: 374163103<br>LEI: 549300T282D7Z2YESL90 | Long             | EC               | CORP              | US        |   1444719 | NS      | $2427127.92    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc                               | GILEAD SCIENCES                           | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |   3726968 | NS      | $555131883.60  | 2.74%             |  |  |  | No            |                  1 | On Loan: No      |
| Ginkgo Bioworks Holdings Inc                      | GINKGO BIOWORKS                           | CUSIP: 37611X209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     99142 | NS      | $669208.50     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Glaukos Corp                                      | GLAUKOS CORP                              | CUSIP: 377322102<br>LEI: 5299004JA1LHE21M6T14 | Long             | EC               | CORP              | US        |    172163 | NS      | $20728425.20   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Medical Inc                                | GLOBUS MEDICAL I                          | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |    338061 | NS      | $32271303.06   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| GoodRx Holdings Inc                               | GOODRX HOLDIN-A                           | CUSIP: 38246G108<br>LEI: 529900ATKYECI45EHV09 | Long             | EC               | CORP              | US        |    259964 | NS      | $486132.68     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Gossamer Bio Inc                                  | GOSSAMER BIO INC                          | CUSIP: 38341P102<br>LEI: 549300ZOC0N2W6PSFR58 | Long             | EC               | CORP              | US        |    546631 | NS      | $232263.51     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| GRAIL Inc                                         | GRAIL INC                                 | CUSIP: 384747101<br>LEI: 2549009XSNESW3VE8024 | Long             | EC               | CORP              | US        |    109914 | NS      | $5850722.22    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health Inc                               | GUARDANT HEALTH                           | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |    336935 | NS      | $31638196.50   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| New Issuer: BB Company ID:69588108                | GUARDIAN PHARM-A                          | CUSIP: 40145W101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     59909 | NS      | $2007550.59    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| HCA Healthcare Inc                                | HCA HEALTHCARE I                          | CUSIP: 40412C101<br>LEI: 529900PH4ZGUH2MNEU89 | Long             | EC               | CORP              | US        |    491993 | NS      | $260608692.10  | 1.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Haemonetics Corp                                  | HAEMONETICS CORP                          | CUSIP: 405024100<br>LEI: 549300ZEL6TXZS6F5F95 | Long             | EC               | CORP              | US        |    144618 | NS      | $9157211.76    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc                         | HALOZYME THERAPE                          | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |    351232 | NS      | $24421160.96   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings Inc                  | HARMONY BIOSCIE                           | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    129197 | NS      | $3687282.38    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Harrow Inc                                        | HARROW INC                                | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     94320 | NS      | $5110257.60    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| HealthStream Inc                                  | HEALTHSTREAM INC                          | CUSIP: 42222N103<br>LEI: 529900OJ88H8635JNH64 | Long             | EC               | CORP              | US        |     70648 | NS      | $1499857.04    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Health Catalyst Inc                               | HEALTH CATALYST                           | CUSIP: 42225T107<br>LEI: 549300223PL6GWKVJG92 | Long             | EC               | CORP              | US        |    210413 | NS      | $340869.06     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| HealthEquity Inc                                  | HEALTHEQUITY INC                          | CUSIP: 42226A107<br>LEI: 529900LRJU1RAFQHM467 | Long             | EC               | CORP              | US        |    258711 | NS      | $19788804.39   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Heron Therapeutics Inc                            | HERON THERAPEUTI                          | CUSIP: 427746102<br>LEI: 549300DR2I1DOPD2IX53 | Long             | EC               | CORP              | US        |    418992 | NS      | $498600.48     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Hims & Hers Health Inc                            | HIMS & HERS HEAL                          | CUSIP: 433000106<br>LEI: 549300ZQ4ZUYSAAX6P59 | Long             | EC               | CORP              | US        |    588146 | NS      | $8539879.92    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| New Issuer: BB Company ID:54419104                | HINGE HEALTH-A                            | CUSIP: 433313103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49070 | NS      | $2098233.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                                       | HOLOGIC INC                               | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |    668037 | NS      | $50343268.32   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Humana Inc                                        | HUMANA INC                                | CUSIP: 444859102<br>LEI: 529900YLDW34GJAO4J06 | Long             | EC               | CORP              | US        |    361264 | NS      | $68835242.56   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Humacyte Inc                                      | HUMACYTE INC                              | CUSIP: 44486Q103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    478723 | NS      | $533776.15     | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| ICU Medical Inc                                   | ICU MEDICAL                               | CUSIP: 44930G107<br>LEI: 5493003NRW7LS2QZRH60 | Long             | EC               | CORP              | US        |     70368 | NS      | $10596013.44   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| IRhythm Holdings Inc                              | IRHYTHM HOLDINGS                          | CUSIP: 450056106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96472 | NS      | $12903130.00   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Ideaya Biosciences Inc                            | IDEAYA BIOSCIENC                          | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |    236466 | NS      | $7614205.20    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEXX Laboratories Inc                            | IDEXX LABS                                | CUSIP: 45168D104<br>LEI: OGMTXK0LUU1HKV2P0J84 | Long             | EC               | CORP              | US        |    240318 | NS      | $157824040.14  | 0.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                                      | ILLUMINA INC                              | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |    461713 | NS      | $62081929.98   | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| ImmunityBio Inc                                   | IMMUNITYBIO INC                           | CUSIP: 45256X103<br>LEI: 529900J9XLBR4HFL4B83 | Long             | EC               | CORP              | US        |    995597 | NS      | $9736938.66    | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| Immunome Inc                                      | IMMUNOME INC                              | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    281599 | NS      | $6155754.14    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant Inc                                    | IMMUNOVANT INC                            | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    240076 | NS      | $6657307.48    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corp                                       | INCYTE CORP                               | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |    498639 | NS      | $50497171.53   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Indivior Pharmaceuticals Inc                      | INDIVIOR PHARMAC                          | CUSIP: 45579U109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    262144 | NS      | $8577351.68    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                                        | INSMED INC                                | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    634927 | NS      | $94813648.91   | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc                       | INSPIRE MEDICAL                           | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |     84281 | NS      | $5436967.31    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Innoviva Inc                                      | INNOVIVA INC                              | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |    180655 | NS      | $4147838.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corp                                      | INSULET CORP                              | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |    211484 | NS      | $52154069.24   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Integra LifeSciences Holdings Corp                | INTEGRA LIFESCIE                          | CUSIP: 457985208<br>LEI: WB7IJCYY8YFTENS4O147 | Long             | EC               | CORP              | US        |    199829 | NS      | $2274054.02    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Integer Holdings Corp                             | INTEGER HOLDINGS                          | CUSIP: 45826H109<br>LEI: 549300SUD2ED5XG6X569 | Long             | EC               | CORP              | US        |    105115 | NS      | $9111368.20    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc                         | INTELLIA THERAPE                          | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |    306922 | NS      | $4229385.16    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc                            | INTUITIVE SURGIC                          | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |   1076772 | NS      | $542165469.72  | 2.68%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals Inc                         | IONIS PHARMACEUT                          | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |    455079 | NS      | $36929660.85   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics Inc                       | IOVANCE BIOTHERA                          | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |    925454 | NS      | $3572252.44    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| iRadimed Corp                                     | IRADIMED CORP                             | CUSIP: 46266A109<br>LEI: 549300YVHWP0YJ1YW816 | Long             | EC               | CORP              | US        |     24989 | NS      | $2587111.17    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc                                | IQVIA HOLDINGS I                          | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |    510647 | NS      | $91308790.07   | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Ironwood Pharmaceuticals Inc                      | IRONWOOD PHARMAC                          | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |    439728 | NS      | $1503869.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Perspective Therapeutics Inc                      | PERSPECTIVE THER                          | CUSIP: 46489V302<br>LEI: 5493005LRKM6BCABC605 | Long             | EC               | CORP              | US        |    290827 | NS      | $1570465.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Janux Therapeutics Inc                            | JANUX THERAPEUTI                          | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    118129 | NS      | $1607735.69    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Johnson & Johnson                                 | JOHNSON&JOHNSON                           | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |   7133723 | NS      | $1772230804.89 | 8.74%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals Inc                      | KALVISTA PHARMAC                          | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |     83620 | NS      | $1361333.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Keros Therapeutics Inc                            | KEROS THERAPEUTI                          | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49534 | NS      | $702887.46     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Kodiak Sciences Inc                               | KODIAK SCIENCES                           | CUSIP: 50015M109<br>LEI: 254900IXI5NI8C9OQE24 | Long             | EC               | CORP              | US        |     87302 | NS      | $2339693.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Korro Bio Inc                                     | KORRO BIO INC                             | CUSIP: 500946108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13803 | NS      | $167430.39     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech Inc                               | KRYSTAL BIOTECH                           | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |     65163 | NS      | $17961529.32   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology Inc                                 | KURA ONCOLOGY IN                          | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |    221971 | NS      | $1937806.83    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc                           | KYMERA THERAPEUT                          | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    143196 | NS      | $13080954.60   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Labcorp Holdings Inc                              | LABCORP HOLDINGS                          | CUSIP: 504922105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    249627 | NS      | $72172158.24   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Lantheus Holdings Inc                             | LANTHEUS HOLDING                          | CUSIP: 516544103<br>LEI: 5299005HUB5IOJGO7S39 | Long             | EC               | CORP              | US        |    203875 | NS      | $15272276.25   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| LeMaitre Vascular Inc                             | LEMAITRE VASCULA                          | CUSIP: 525558201<br>LEI: 549300FZUBUB7MHY8R17 | Long             | EC               | CORP              | US        |     64342 | NS      | $6960517.56    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| LENZ Therapeutics Inc                             | LENZ THERAPEUTIC                          | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     35168 | NS      | $474416.32     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Lexicon Pharmaceuticals Inc                       | LEXICON PHARMACE                          | CUSIP: 528872302<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    548799 | NS      | $806734.53     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ligand Pharmaceuticals Inc                        | LIGAND PHARM                              | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |     58943 | NS      | $11688986.33   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| LifeStance Health Group Inc                       | LIFESTANCE HEALT                          | CUSIP: 53228F101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    526228 | NS      | $3809890.72    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                                    | ELI LILLY & CO                            | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |   2416386 | NS      | $2542013908.14 | 12.54%            |  |  |  | No            |                  1 | On Loan: No      |
| Liquidia Corp                                     | LIQUIDIA CORP                             | CUSIP: 53635D202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    180682 | NS      | $5604755.64    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Lyell Immunopharma Inc                            | LYELL IMMUNOPHAR                          | CUSIP: 55083R203<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23103 | NS      | $554472.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| MBX Biosciences Inc                               | MBX BIOSCIENCES                           | CUSIP: 55287L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     67179 | NS      | $2186676.45    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MacroGenics Inc                                   | MACROGENICS INC                           | CUSIP: 556099109<br>LEI: 5493001KJQUA83L8MH79 | Long             | EC               | CORP              | US        |    155000 | NS      | $308450.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Madrigal Pharmaceuticals Inc                      | MADRIGAL PHARMAC                          | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |     43490 | NS      | $18787680.00   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| MannKind Corp                                     | MANNKIND CORP                             | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |    877153 | NS      | $2877061.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Maravai LifeSciences Holdings Inc                 | MARAVAI LIFESC-A                          | CUSIP: 56600D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    326406 | NS      | $1162005.36    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Masimo Corp                                       | MASIMO CORP                               | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |    138644 | NS      | $24311225.40   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| MaxCyte Inc                                       | MAXCYTE INC                               | CUSIP: 57777K106<br>LEI: 54930053YHXULRFCU991 | Long             | EC               | CORP              | US        |    304528 | NS      | $247063.57     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| McKesson Corp                                     | MCKESSON CORP                             | CUSIP: 58155Q103<br>LEI: 549300WZWOM80UCFSF54 | Long             | EC               | CORP              | US        |    373609 | NS      | $368890318.33  | 1.82%             |  |  |  | No            |                  1 | On Loan: No      |
| Pediatrix Medical Group Inc                       | PEDIATRIX MEDICA                          | CUSIP: 58502B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    262030 | NS      | $5201295.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Medpace Holdings Inc                              | MEDPACE HOLDINGS                          | CUSIP: 58506Q109<br>LEI: 549300H8TYEUVTW14A54 | Long             | EC               | CORP              | US        |     67472 | NS      | $30481150.72   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Medline Inc                                       | MEDLINE INC-A                             | CUSIP: 58507V107<br>LEI: 984500FAN6J1P8566D43 | Long             | EC               | CORP              | US        |    495333 | NS      | $23533270.83   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Merck & Co Inc                                    | MERCK & CO                                | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |   7502422 | NS      | $928949892.04  | 4.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Merit Medical Systems Inc                         | MERIT MEDICAL                             | CUSIP: 589889104<br>LEI: 549300OYTY138SP2CE83 | Long             | EC               | CORP              | US        |    177831 | NS      | $13724996.58   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Mesa Laboratories Inc                             | MESA LABS                                 | CUSIP: 59064R109<br>LEI: 549300ZCG738WLX8ZW79 | Long             | EC               | CORP              | US        |     16578 | NS      | $1600937.46    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Mettler-Toledo International Inc                  | METTLER-TOLEDO                            | CUSIP: 592688105<br>LEI: 5493000BD5GJNUDIUG10 | Long             | EC               | CORP              | US        |     61877 | NS      | $84566677.13   | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| MiMedx Group Inc                                  | MIMEDX GROUP INC                          | CUSIP: 602496101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    357721 | NS      | $1749255.69    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Mineralys Therapeutics Inc                        | MINERALYS THERAP                          | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    136784 | NS      | $4002299.84    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharmaceuticals Inc                         | MIRUM PHARMACEUT                          | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |    113228 | NS      | $10449812.12   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                                       | MODERNA INC                               | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |    910261 | NS      | $48762681.77   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Molina Healthcare Inc                             | MOLINA HEALTHCAR                          | CUSIP: 60855R100<br>LEI: 549300NQQCEQ46YHZ591 | Long             | EC               | CORP              | US        |    162724 | NS      | $25067632.20   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics Inc                       | MONTE ROSA THERA                          | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     93371 | NS      | $1657335.25    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MoonLake Immunotherapeutics                       | MOONLAKE IMMUNOT                          | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95724 | NS      | $1676127.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Multiplan Corp                                    | CLARITEV CORP                             | CUSIP: 62548M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     17334 | NS      | $233488.98     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Myriad Genetics Inc                               | MYRIAD GENETICS                           | CUSIP: 62855J104<br>LEI: 52990044IHUOUMETT163 | Long             | EC               | CORP              | US        |    276946 | NS      | $1276721.06    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc                                        | NATERA INC                                | CUSIP: 632307104<br>LEI: 529900CQ3OZ0A0VYVU59 | Long             | EC               | CORP              | US        |    391672 | NS      | $81483442.88   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| National HealthCare Corp                          | NATL HEALTHCARE                           | CUSIP: 635906100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     39512 | NS      | $6460212.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Nektar Therapeutics                               | NEKTAR THERAPEUT                          | CUSIP: 640268306<br>LEI: 5299005I24806IOIYE03 | Long             | EC               | CORP              | US        |     72788 | NS      | $5020916.24    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Neogen Corp                                       | NEOGEN CORP                               | CUSIP: 640491106<br>LEI: 549300HJT9FC36N4UW43 | Long             | EC               | CORP              | US        |    618347 | NS      | $6944036.81    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| NeoGenomics Inc                                   | NEOGENOMICS INC                           | CUSIP: 64049M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    385729 | NS      | $3791716.07    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Neumora Therapeutics Inc                          | NEUMORA THERAPEU                          | CUSIP: 640979100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    171100 | NS      | $597139.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc                        | NEUROCRINE BIOSC                          | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |    297785 | NS      | $39382066.25   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Novavax Inc                                       | NOVAVAX INC                               | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |    415421 | NS      | $4212368.94    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Nuvalent Inc                                      | NUVALENT INC-A                            | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    119973 | NS      | $12231247.35   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics Inc                            | NURIX THERAPEUTI                          | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    227843 | NS      | $3638652.71    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvation Bio Inc                                  | NUVATION BIO INC                          | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    667444 | NS      | $3944594.04    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocular Therapeutix Inc                            | OCULAR THERAPEUT                          | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |    478485 | NS      | $4277655.90    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocugen Inc                                        | OCUGEN INC                                | CUSIP: 67577C105<br>LEI: 549300JVNUI9CXWJLR09 | Long             | EC               | CORP              | US        |    939571 | NS      | $1710019.22    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Olema Pharmaceuticals Inc                         | OLEMA PHARMACEUT                          | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113615 | NS      | $2749483.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Omnicell Inc                                      | OMNICELL INC                              | CUSIP: 68213N109<br>LEI: 5493008RH0GTKHHPZI77 | Long             | EC               | CORP              | US        |    138185 | NS      | $5679403.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Omeros Corp                                       | OMEROS CORP                               | CUSIP: 682143102<br>LEI: 549300CJWLXX2MXVVV71 | Long             | EC               | CORP              | US        |    204515 | NS      | $2464405.75    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| OmniAb Inc                                        | OMNIAB INC                                | CUSIP: 68218J103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    259648 | NS      | $446594.56     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC - 12.5                         | CUSIP: 68218J202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22076 | NS      | $0.22          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC - 15                           | CUSIP: 68218J301<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22076 | NS      | $0.22          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| OPKO Health Inc                                   | OPKO HEALTH                               | CUSIP: 68375N103<br>LEI: 529900A4S2D4OGOJLL02 | Long             | EC               | CORP              | US        |   1271801 | NS      | $1526161.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Option Care Health Inc                            | OPTION CARE HEAL                          | CUSIP: 68404L201<br>LEI: 549300DI3Q5ACSYJRI17 | Long             | EC               | CORP              | US        |    487139 | NS      | $15812531.94   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| OraSure Technologies Inc                          | ORASURE TECH                              | CUSIP: 68554V108<br>LEI: 529900GNNJPNM4XHXQ77 | Long             | EC               | CORP              | US        |    188856 | NS      | $594896.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Organogenesis Holdings Inc                        | ORGANOGENESIS HO                          | CUSIP: 68621F102<br>LEI: 549300RLC2O821TU6941 | Long             | EC               | CORP              | US        |    190756 | NS      | $612326.76     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC Pharmaceuticals Inc                          | ORIC PHARMACEUTI                          | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |    131478 | NS      | $1768379.10    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Organon & Co                                      | ORGANON & CO                              | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |    782010 | NS      | $5700852.90    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| OrthoPediatrics Corp                              | ORTHOPEDIATRICS                           | CUSIP: 68752L100<br>LEI: 5493000KUTPFGOPAT717 | Long             | EC               | CORP              | US        |     52580 | NS      | $1007958.60    | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Orthofix Medical Inc                              | ORTHOFIX MEDICAL                          | CUSIP: 68752M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     94830 | NS      | $1283049.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics Inc                            | ORUKA THERAPEUTI                          | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |     65417 | NS      | $2250998.97    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Accendra Health Inc                               | ACCENDRA HEALTH                           | CUSIP: 690732102<br>LEI: 549300LMT5KQQXCEZ733 | Long             | EC               | CORP              | US        |    232854 | NS      | $563506.68     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| PTC Therapeutics Inc                              | PTC THERAPEUTICS                          | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |    214672 | NS      | $14638483.68   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| PACS Group Inc                                    | PACS GROUP INC                            | CUSIP: 69380Q107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    139674 | NS      | $5099497.74    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacific Biosciences of California Inc             | PACIFIC BIOSCIEN                          | CUSIP: 69404D108<br>LEI: 529900F1BWRE1M0KZN89 | Long             | EC               | CORP              | US        |    772607 | NS      | $1297979.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacira BioSciences Inc                            | PACIRA BIOSCIENC                          | CUSIP: 695127100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    128410 | NS      | $2813463.10    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pieris Pharmaceuticals Inc                        | PALVELLA THERAPE                          | CUSIP: 697947109<br>LEI: 254900AJDH8PAOOI5T33 | Long             | EC               | CORP              | US        |     23095 | NS      | $3118286.90    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Pennant Group Inc/The                             | PENNANT GROUP-WI                          | CUSIP: 70805E109<br>LEI: 5493007H2OYR6BYLDA64 | Long             | EC               | CORP              | US        |    103054 | NS      | $3473950.34    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Penumbra Inc                                      | PENUMBRA INC                              | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |    111363 | NS      | $38352303.57   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Revvity Inc                                       | REVVITY INC                               | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |    348428 | NS      | $34253956.68   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Personalis Inc                                    | PERSONALIS INC                            | CUSIP: 71535D106<br>LEI: 549300EZ2NYFK7H0US48 | Long             | EC               | CORP              | US        |    159822 | NS      | $1447987.32    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc                                        | PFIZER INC                                | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |  17077295 | NS      | $472187206.75  | 2.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Phathom Pharmaceuticals Inc                       | PHATHOM PHARMACE                          | CUSIP: 71722W107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    126819 | NS      | $1592846.64    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Phibro Animal Health Corp                         | PHIBRO ANIMAL-A                           | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |     60637 | NS      | $3310173.83    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Phreesia Inc                                      | PHREESIA INC                              | CUSIP: 71944F106<br>LEI: 5493000HHF8NU4QOCG53 | Long             | EC               | CORP              | US        |    180017 | NS      | $2219609.61    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pliant Therapeutics Inc                           | PLIANT THERAPEUT                          | CUSIP: 729139105<br>LEI: 5493002Q5LITR7VHZH02 | Long             | EC               | CORP              | US        |    115341 | NS      | $149943.30     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc                    | PRAXIS PRECISION                          | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     70880 | NS      | $23868840.00   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Precigen Inc                                      | PRECIGEN INC                              | CUSIP: 74017N105<br>LEI: 549300XCWNQU35K64G19 | Long             | EC               | CORP              | US        |    532042 | NS      | $2016439.18    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Prestige Consumer Healthcare Inc                  | PRESTIGE CONSUME                          | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    147756 | NS      | $10239490.80   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Prime Medicine Inc                                | PRIME MEDICINE I                          | CUSIP: 74168J101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    259551 | NS      | $1199125.62    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BioRobotics Corp                          | PROCEPT BIOROBOT                          | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    166491 | NS      | $3777680.79    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Privia Health Group Inc                           | PRIVIA HEALTH GR                          | CUSIP: 74276R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    294382 | NS      | $6991572.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Progyny Inc                                       | PROGYNY INC                               | CUSIP: 74340E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    246071 | NS      | $4352995.99    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc                      | PROTAGONIST THER                          | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    149400 | NS      | $13756752.00   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Pulse Biosciences Inc                             | PULSE BIOSCIENCE                          | CUSIP: 74587B101<br>LEI: 529900NJUBI06118FM73 | Long             | EC               | CORP              | US        |     61062 | NS      | $1143691.26    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Quantum-Si Inc                                    | QUANTUM-SI INC                            | CUSIP: 74765K105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    493459 | NS      | $471944.19     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Quanterix Corp                                    | QUANTERIX CORP                            | CUSIP: 74766Q101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    125718 | NS      | $823452.90     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Quest Diagnostics Inc                             | QUEST DIAGNOSTIC                          | CUSIP: 74834L100<br>LEI: 8MCWUBXQ0WE04KMXBX50 | Long             | EC               | CORP              | US        |    336002 | NS      | $71202183.82   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| RadNet Inc                                        | RADNET INC                                | CUSIP: 750491102<br>LEI: 529900RECG94V2IZJ970 | Long             | EC               | CORP              | US        |    196292 | NS      | $13703144.52   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Rapport Therapeutics Inc                          | RAPPORT THERAPEU                          | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     82151 | NS      | $2384843.53    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Recursion Pharmaceuticals Inc                     | RECURSION PHAR-A                          | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1099178 | NS      | $4033983.26    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Regeneron Pharmaceuticals Inc                     | REGENERON PHARM                           | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |    312898 | NS      | $244582979.66  | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| REGENXBIO Inc                                     | REGENXBIO INC                             | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |    127897 | NS      | $1156188.88    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc                            | RELAY THERAPEUTI                          | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    361043 | NS      | $3704301.18    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Repligen Corp                                     | REPLIGEN CORP                             | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |    160466 | NS      | $20656788.18   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc                               | REPLIMUNE GROUP                           | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |    140906 | NS      | $1077930.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc                                        | RESMED INC                                | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |    438376 | NS      | $112338233.76  | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION Medicines Inc                          | REVOLUTION MEDIC                          | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |    420864 | NS      | $42936545.28   | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                                      | REZOLUTE INC                              | CUSIP: 76200L309<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    218368 | NS      | $700961.28     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc                        | RHYTHM PHARMACEU                          | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |    169467 | NS      | $15714674.91   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Rocket Pharmaceuticals Inc                        | ROCKET PHARMACEU                          | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |    244381 | NS      | $1224348.81    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| RxSight Inc                                       | RXSIGHT INC                               | CUSIP: 78349D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    104675 | NS      | $782969.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc                            | SANA BIOTECHNOLO                          | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    512461 | NS      | $2157460.81    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics Inc                          | SAREPTA THERAPEU                          | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |    299230 | NS      | $5015094.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara Inc                                        | SAVARA INC                                | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |    207988 | NS      | $1252087.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Henry Schein Inc                                  | HENRY SCHEIN INC                          | CUSIP: 806407102<br>LEI: VGO3WGL8H45T73F4RR92 | Long             | EC               | CORP              | US        |    327739 | NS      | $27002416.21   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp                         | SCHOLAR ROCK HOL                          | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |    187838 | NS      | $8315588.26    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Schrodinger Inc/United States                     | SCHRODINGER INC                           | CUSIP: 80810D103<br>LEI: 984500044BAE4791E559 | Long             | EC               | CORP              | US        |    192621 | NS      | $2323009.26    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Select Medical Holdings Corp                      | SELECT MEDICAL                            | CUSIP: 81619Q105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    335688 | NS      | $5025249.36    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| GeneDx Holdings Corp                              | GENEDX HOLDINGS                           | CUSIP: 81663L200<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     60512 | NS      | $4823411.52    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Septerna Inc                                      | SEPTERNA INC                              | CUSIP: 81734D104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     33480 | NS      | $971589.60     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| SI-BONE Inc                                       | SI-BONE INC                               | CUSIP: 825704109<br>LEI: 549300J8JGYVJJHV9C31 | Long             | EC               | CORP              | US        |    123190 | NS      | $1911908.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| SIGA Technologies Inc                             | SIGA TECH INC                             | CUSIP: 826917106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    130376 | NS      | $843532.72     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ARS Pharmaceuticals Inc                           | ARS PHARMACEUTIC                          | CUSIP: 82835W108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    163427 | NS      | $1516602.56    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Simulations Plus Inc                              | SIMULATIONS PLUS                          | CUSIP: 829214105<br>LEI: 529900KYRDJAQ8TJCG93 | Long             | EC               | CORP              | US        |     52274 | NS      | $639311.02     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Soleno Therapeutics Inc                           | SOLENO THERAPEUT                          | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |    135961 | NS      | $5311996.27    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Solventum Corp                                    | SOLVENTUM                                 | CUSIP: 83444M101<br>LEI: 254900I70403OSGY4M28 | Long             | EC               | CORP              | US        |    467661 | NS      | $34700446.20   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Sotera Health Co                                  | SOTERA HEALTH CO                          | CUSIP: 83601L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    639602 | NS      | $10393532.50   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| STAAR Surgical Co                                 | STAAR SURGICAL                            | CUSIP: 852312305<br>LEI: 5299006LRHI7OJ8BY308 | Long             | EC               | CORP              | US        |     96492 | NS      | $1920190.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc                            | STOKE THERAPEUTI                          | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |    115694 | NS      | $4212418.54    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Stryker Corp                                      | STRYKER CORP                              | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |   1033542 | NS      | $400456183.32  | 1.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Summit Therapeutics Inc                           | SUMMIT THERAPEUT                          | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    446795 | NS      | $7412329.05    | 0.04%             |  |  |  | No            |                  1 | On Loan: —       |
| Supernus Pharmaceuticals Inc                      | SUPERNUS PHARMAC                          | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |    168276 | NS      | $9209745.48    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Surgery Partners Inc                              | SURGERY PARTNERS                          | CUSIP: 86881A100<br>LEI: 549300LC82HG33S19I03 | Long             | EC               | CORP              | US        |    232138 | NS      | $3598139.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Syndax Pharmaceuticals Inc                        | SYNDAX PHARMACEU                          | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |    244836 | NS      | $5315389.56    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Tactile Systems Technology Inc                    | TACTILE SYSTEMS                           | CUSIP: 87357P100<br>LEI: 54930069VDTITHOTKJ98 | Long             | EC               | CORP              | US        |     66842 | NS      | $1957802.18    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Talkspace Inc                                     | TALKSPACE INC                             | CUSIP: 87427V103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    420757 | NS      | $2028048.74    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Tandem Diabetes Care Inc                          | TANDEM DIABETES                           | CUSIP: 875372203<br>LEI: 549300JEPFOD0K4D3I05 | Long             | EC               | CORP              | US        |    202104 | NS      | $5113231.20    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics Inc                            | TANGO THERAPEUTI                          | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    135189 | NS      | $1506005.46    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Tarsus Pharmaceuticals Inc                        | TARSUS PHARMACEU                          | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95350 | NS      | $7200832.00    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Taysha Gene Therapies Inc                         | TAYSHA GENE THER                          | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    410659 | NS      | $1860285.27    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Teladoc Health Inc                                | TELADOC HEALTH I                          | CUSIP: 87918A105<br>LEI: 549300I2PVFBC9MFAC61 | Long             | EC               | CORP              | US        |    532825 | NS      | $2802659.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Teleflex Inc                                      | TELEFLEX INC                              | CUSIP: 879369106<br>LEI: UUL85LWXB4NGSWWXIQ25 | Long             | EC               | CORP              | US        |    132670 | NS      | $16193700.20   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Tempus AI Inc                                     | TEMPUS AI INC-A                           | CUSIP: 88023B103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    278536 | NS      | $14832042.00   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc                                  | 10X GENOMICS I-A                          | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |    309840 | NS      | $7141812.00    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Tenet Healthcare Corp                             | TENET HEALTHCARE                          | CUSIP: 88033G407<br>LEI: 0W9AIBT6U6ADJ2I8HK17 | Long             | EC               | CORP              | US        |    265410 | NS      | $63536499.90   | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| Terns Pharmaceuticals Inc                         | TERNS PHARMACEUT                          | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |    170728 | NS      | $7191063.36    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| TG Therapeutics Inc                               | TG THERAPEUTICS                           | CUSIP: 88322Q108<br>LEI: 529900X21UKABN9NJ529 | Long             | EC               | CORP              | US        |    452550 | NS      | $13617229.50   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc                      | THERMO FISHER                             | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |   1134220 | NS      | $591053384.20  | 2.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Tilray Brands Inc                                 | TILRAY BRANDS IN                          | CUSIP: 88688T209<br>LEI: 549300Y4V60733TO1478 | Long             | EC               | CORP              | US        |    337884 | NS      | $2659147.08    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| TransMedics Group Inc                             | TRANSMEDICS GROU                          | CUSIP: 89377M109<br>LEI: 549300060GVOSMWARH50 | Long             | EC               | CORP              | US        |     97232 | NS      | $14123920.32   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Travere Therapeutics Inc                          | TRAVERE THERAPEU                          | CUSIP: 89422G107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    253607 | NS      | $7554952.53    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Treace Medical Concepts Inc                       | TREACE MEDICAL C                          | CUSIP: 89455T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    151893 | NS      | $282520.98     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Trevi Therapeutics Inc                            | TREVI THERAPEUTI                          | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    256138 | NS      | $3053164.96    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Prevail Therapeutics Inc                          | PREVAIL THERAPEU - CVR                    | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |        78 | NS      | $39.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Twist Bioscience Corp                             | TWIST BIOSCIENCE                          | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |    180862 | NS      | $8486045.04    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Tyra Biosciences Inc                              | TYRA BIOSCIENCES                          | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     40280 | NS      | $1341726.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| UFP Technologies Inc                              | UFP TECHNOLOGIES                          | CUSIP: 902673102<br>LEI: 549300RJ8LY41HS70C91 | Long             | EC               | CORP              | US        |     21923 | NS      | $4616545.34    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| US Physical Therapy Inc                           | US PHYSICAL THER                          | CUSIP: 90337L108<br>LEI: 529900KL1UXQYFIOMY96 | Long             | EC               | CORP              | US        |     45359 | NS      | $3762982.64    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceutical Inc                     | ULTRAGENYX PHARM                          | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |    261089 | NS      | $6106871.71    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| United Therapeutics Corp                          | UNITED THERAPEUT                          | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |    129071 | NS      | $65038876.90   | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc                            | UNITEDHEALTH GRP                          | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |   2720307 | NS      | $797784433.89  | 3.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Universal Health Services Inc                     | UNIVERSAL HLTH-B                          | CUSIP: 913903100<br>LEI: 549300YGMGQDO0NMJD09 | Long             | EC               | CORP              | US        |    169327 | NS      | $34898294.70   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Upstream Bio Inc                                  | UPSTREAM BIO INC                          | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     40484 | NS      | $310917.12     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanda Pharmaceuticals Inc                         | VANDA PHARMACEUT                          | CUSIP: 921659108<br>LEI: 529900AY8VOOQBKJ0O70 | Long             | EC               | CORP              | US        |    168602 | NS      | $1502243.82    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Varex Imaging Corp                                | VAREX IMAGIN                              | CUSIP: 92214X106<br>LEI: 549300CWYWPVCT8E9W67 | Long             | EC               | CORP              | US        |    124595 | NS      | $1640916.15    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Vaxcyte Inc                                       | VAXCYTE INC                               | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |    350670 | NS      | $21650365.80   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                                 | VEEVA SYSTEMS-A                           | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |    467719 | NS      | $85129535.19   | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Ventyx Biosciences Inc                            | VENTYX BIOSCIENC                          | CUSIP: 92332V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    171667 | NS      | $2398187.99    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Verastem Inc                                      | VERASTEM INC                              | CUSIP: 92337C203<br>LEI: 549300IY0EFBIU8NQC81 | Long             | EC               | CORP              | US        |    129463 | NS      | $740528.36     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                                      | VERACYTE INC                              | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |    236093 | NS      | $8638642.87    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Vera Therapeutics Inc                             | VERA THERAPEUTIC                          | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    115268 | NS      | $4701781.72    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vericel Corp                                      | VERICEL CORP                              | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |    151967 | NS      | $5422182.56    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Inc                        | VERTEX PHARM                              | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |    770119 | NS      | $382618222.77  | 1.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Viatris Inc                                       | VIATRIS INC                               | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |   3502600 | NS      | $52293818.00   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Viking Therapeutics Inc                           | VIKING THERAPEUT                          | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    320505 | NS      | $10845889.20   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Vir Biotechnology Inc                             | VIR BIOTECHNOLOG                          | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    317494 | NS      | $2886020.46    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Viridian Therapeutics Inc                         | VIRIDIAN THERAPE                          | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |    196143 | NS      | $5762681.34    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corp                                       | WATERS CORP                               | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |    295312 | NS      | $94316637.97   | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Waystar Holding Corp                              | WAYSTAR HOLDING                           | CUSIP: 946784105<br>LEI: 529900QJLKXDYU36MH89 | Long             | EC               | CORP              | US        |    343764 | NS      | $8817546.60    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Inc                  | WEST PHARMACEUT                           | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |    215998 | NS      | $54936931.32   | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor Inc                                        | XENCOR INC                                | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |    181669 | NS      | $2319913.13    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| XOMA Royalty Corp                                 | XOMA ROYALTY COR                          | CUSIP: 98419J206<br>LEI: 549300U6ZVYFCWNBJ613 | Long             | EC               | CORP              | US        |     29011 | NS      | $740650.83     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc                      | XERIS BIOPHARMA                           | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    484655 | NS      | $2966088.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Zenas Biopharma Inc                               | ZENAS BIOPHARMA                           | CUSIP: 98937L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     48147 | NS      | $1268673.45    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Zentalis Pharmaceuticals Inc                      | ZENTALIS PHARMAC                          | CUSIP: 98943L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    151885 | NS      | $363005.15     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Zimmer Biomet Holdings Inc                        | ZIMMER BIOMET HO                          | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |    595279 | NS      | $58599264.76   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Zoetis Inc                                        | ZOETIS INC                                | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |   1331195 | NS      | $174519664.50  | 0.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Zymeworks Inc                                     | ZYMEWORKS INC                             | CUSIP: 98985Y108<br>LEI: 894500AHOYAGYLYZJL67 | Long             | EC               | CORP              | US        |    112792 | NS      | $2626925.68    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Newamsterdam Pharma Co NV                         | NEWAMSTERDAM PHA                          | CUSIP: N/A<br>LEI: 984500B6549TF6E14D36       | Long             | EC               | CORP              | US        |    135570 | NS      | $4807312.20    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanguard Cmt Funds-Vanguard Market Liquidity Fund | Vanguard Market Liquidity Fund            | CUSIP: N/A<br>LEI: 1I6HV0TLSTR3A4XQ6L78       | Long             | STIV             | CORP              | US        |  14693190 | NS      | $14691720.88   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes PLC                                      | ALKERMES PLC                              | CUSIP: G01767105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    470774 | NS      | $14170297.40   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                                      | BIOHAVEN LTD                              | CUSIP: G1110E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    350058 | NS      | $4032668.16    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Establishment Labs Holdings Inc                   | ESTABLISHMENT LA                          | CUSIP: G31249108<br>LEI: 549300BCBQ714JNJ7V58 | Long             | EC               | CORP              | US        |     52485 | NS      | $4130569.50    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC                          | JAZZ PHARMACEUTI                          | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | US        |    163920 | NS      | $31148078.40   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Kestra Medical Technologies In                    | KESTRA MEDICAL T                          | CUSIP: G52441105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     60579 | NS      | $1410279.12    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Kiniksa Pharmaceuticals International Plc         | KINIKSA PHARMACE                          | CUSIP: G52694109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    104651 | NS      | $4655922.99    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| LivaNova PLC                                      | LIVANOVA PLC                              | CUSIP: G5509L101<br>LEI: 2138001K2FX6SHK2B339 | Long             | EC               | CORP              | US        |    163864 | NS      | $11568798.40   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Medtronic PLC                                     | MEDTRONIC PLC                             | CUSIP: G5960L103<br>LEI: 549300GX3ZBSQWUXY261 | Long             | EC               | CORP              | US        |   3852793 | NS      | $376263764.38  | 1.86%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings plc                             | MEIRAGTX HOLDING                          | CUSIP: G59665102<br>LEI: 54930007YV6NYIOGFZ57 | Long             | EC               | CORP              | US        |    131531 | NS      | $994374.36     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Novocure Ltd                                      | NOVOCURE LTD                              | CUSIP: G6674U108<br>LEI: 213800YPP55UMHWA4826 | Long             | EC               | CORP              | US        |    319728 | NS      | $4370681.76    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corp PLC                                 | PROTHENA CORP PL                          | CUSIP: G72800108<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | US        |    137710 | NS      | $1193945.70    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                              | ROIVANT SCIENCES                          | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | US        |   1127488 | NS      | $32629502.72   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| STERIS PLC                                        | STERIS PLC                                | CUSIP: G8473T100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    295869 | NS      | $74662542.15   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Theravance Biopharma Inc                          | THERAVANCE B                              | CUSIP: G8807B106<br>LEI: 5493007VTSXP4Z6MIW52 | Long             | EC               | CORP              | US        |    114278 | NS      | $2085573.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Perrigo Co PLC                                    | PERRIGO CO PLC                            | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | US        |    412875 | NS      | $5458207.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| UroGen Pharma Ltd                                 | UROGEN PHARMA LT                          | CUSIP: M96088105<br>LEI: 549300C0YCX7CG2G5D50 | Long             | EC               | CORP              | US        |    118186 | NS      | $2564636.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanguard Cmt Funds-Vanguard Market Liquidity Fund | Vanguard Market Liquidity Fund            | CUSIP: N/A<br>LEI: 1I6HV0TLSTR3A4XQ6L78       | Long             | STIV             | CORP              | US        |    240226 | NS      | $24020245.24   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | TRS:JOHNSON & JOHNSON USD 2027-Jan-29     | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    100000 | NC      | $510000.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                               | TRS:ELEVANCE HEALTH INC USD 2026-Aug-31   | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |     11242 | NC      | $-118153.42    | -0.00%            |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                               | TRS:MODERNA INC USD 2026-Aug-31           | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    145000 | NC      | $319000.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| WaVe Life Sciences Ltd                            | WAVE LIFE SCIENC                          | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | US        |    334197 | NS      | $4655364.21    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-04-27

**Name of Applicant:** VANGUARD WORLD FUND

**Signature:** Ashley Grim

**Name of Signer:** Ashley Grim

**Title:** Treasurer