# EDGAR Filing Document

**Accession Number:** 0001778253
**File Stem:** 0001420506-25-002181
**Filing Date:** 2025-8
**Character Count:** 17362
**Document Hash:** f190af5edcfa7dad0ce15d2ba86ad59f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001420506-25-002181.hdr.sgml**: 20250814

**ACCESSION NUMBER**: 0001420506-25-002181

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250814

**DATE AS OF CHANGE**: 20250814

**EFFECTIVENESS DATE**: 20250814

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Ikarian Capital, LLC
- **CENTRAL INDEX KEY:** 0001778253

**ORGANIZATION NAME:**
- **EIN:** 473466768
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-19721
- **FILM NUMBER:** 251219762

**BUSINESS ADDRESS:**
- **STREET 1:** 100 CRESCENT COURT
- **STREET 2:** SUITE 1620
- **CITY:** DALLAS
- **STATE:** TX
- **ZIP:** 75201
- **BUSINESS PHONE:** 214-364-2883

**MAIL ADDRESS:**
- **STREET 1:** 100 CRESCENT COURT
- **STREET 2:** SUITE 1620
- **CITY:** DALLAS
- **STATE:** TX
- **ZIP:** 75201

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 06-30-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** Ikarian Capital LLC<br>**Address:** 100 CRESCENT COURT<br>SUITE 1620<br>DALLAS, TX 75201

**Form 13F File Number:** 028-19721

**SEC File Number (if applicable):** 801-118894

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Troy Wuertz<br>**Title:** CHIEF COMPLIANCE OFFICER<br>**Phone:** 214-276-0670

**Signature, Place, and Date of Signing:**

Troy Wuertz CHIEF COMPLIANCE OFFICER  DALLAS, TX  08-14-2025<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 133

**Form 13F Information Table Value Total:** $520629177

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| ACUMEN PHARMACEUTICALS INC | COM | 00509G209 |  | 308292 | 265769 | SH |  | SOLE |  | 265769 | 0 | 0 |
| AETHLON MED INC | COM NEW | 00808Y505 |  | 184391 | 153659 | SH |  | SOLE |  | 153659 | 0 | 0 |
| AIRSCULPT TECHNOLOGIES INC | COM | 009496100 |  | 86703 | 17951 | SH |  | SOLE |  | 17951 | 0 | 0 |
| AKERO THERAPEUTICS INC | COM | 00973Y108 |  | 11739199 | 220000 | SH |  | SOLE |  | 220000 | 0 | 0 |
| AKERO THERAPEUTICS INC | COM | 00973Y108 |  | 2369184 | 44400 | SH | Call | SOLE |  | 44400 | 0 | 0 |
| ALECTOR INC | COM | 014442107 |  | 1260000 | 900000 | SH |  | SOLE |  | 900000 | 0 | 0 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 |  | 18454737 | 56594 | SH |  | SOLE |  | 56594 | 0 | 0 |
| ALPHA COGNITION INC | COM NEW | 02074J501 |  | 8563699 | 917867 | SH |  | SOLE |  | 917867 | 0 | 0 |
| ALPHA TEKNOVA INC | COM | 02080L102 |  | 68779 | 14008 | SH |  | SOLE |  | 14008 | 0 | 0 |
| ALTIMMUNE INC | COM NEW | 02155H200 |  | 3202425 | 827500 | SH | Call | SOLE |  | 827500 | 0 | 0 |
| ALTO NEUROSCIENCE INC | COM SHS | 02157Q109 |  | 242001 | 110000 | SH |  | SOLE |  | 110000 | 0 | 0 |
| ANAPTYSBIO INC | COM | 032724106 |  | 347696 | 15662 | SH |  | SOLE |  | 15662 | 0 | 0 |
| ANEBULO PHARMACEUTICALS INC | COM | 034569103 |  | 227117 | 157720 | SH |  | SOLE |  | 157720 | 0 | 0 |
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 |  | 1298250 | 75000 | SH |  | SOLE |  | 75000 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 10077802 | 232047 | SH |  | SOLE |  | 232047 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 364812 | 8400 | SH | Call | SOLE |  | 8400 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 3435313 | 79100 | SH | Put | SOLE |  | 79100 | 0 | 0 |
| ARCTURUS THERAPEUTICS HLDGS | COM | 03969T109 |  | 2276750 | 175000 | SH |  | SOLE |  | 175000 | 0 | 0 |
| ARCUS BIOSCIENCES INC | COM | 03969F109 |  | 1329775 | 163363 | SH |  | SOLE |  | 163363 | 0 | 0 |
| ARVINAS INC | COM | 04335A105 |  | 6256000 | 850000 | SH |  | SOLE |  | 850000 | 0 | 0 |
| AUTONOMIX MED INC | COM NEW | 05330T205 |  | 31401 | 20000 | SH |  | SOLE |  | 20000 | 0 | 0 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 |  | 176147 | 35300 | SH |  | SOLE |  | 35300 | 0 | 0 |
| BIOGEN INC | COM | 09062X103 |  | 2702195 | 21516 | SH |  | SOLE |  | 21516 | 0 | 0 |
| BIOHAVEN LTD | CALL | G1110E907 |  | 4233000 | 300000 | SH | Call | SOLE |  | 300000 | 0 | 0 |
| BIOMX INC | COM NEW | 09090D301 |  | 401839 | 892976 | SH |  | SOLE |  | 892976 | 0 | 0 |
| BRIGHT MINDS BIOSCIENCES INC | COM NEW | 10919W405 |  | 1708403 | 65431 | SH |  | SOLE |  | 65431 | 0 | 0 |
| CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 |  | 6951000 | 700000 | SH | Call | SOLE |  | 700000 | 0 | 0 |
| CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 |  | 13506786 | 1360200 | SH | Put | SOLE |  | 1360200 | 0 | 0 |
| CARTESIAN THERAPEUTICS INC | COM NEW | 816212302 |  | 230304 | 22166 | SH |  | SOLE |  | 22166 | 0 | 0 |
| CATALYST PHARMACEUTICALS INC | COM | 14888U101 |  | 4549384 | 209649 | SH |  | SOLE |  | 209649 | 0 | 0 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 |  | 2628000 | 200000 | SH | Call | SOLE |  | 200000 | 0 | 0 |
| CG ONCOLOGY INC | COM | 156944100 |  | 4030000 | 155000 | SH |  | SOLE |  | 155000 | 0 | 0 |
| CHEMOMAB THERAPEUTICS LTD | SPONSORED ADS | 16385C104 |  | 247141 | 213052 | SH |  | SOLE |  | 213052 | 0 | 0 |
| CIDARA THERAPEUTICS INC | COM NEW | 171757206 |  | 22625210 | 464488 | SH |  | SOLE |  | 464488 | 0 | 0 |
| CIDARA THERAPEUTICS INC | COM NEW | 171757206 |  | 15635910 | 321000 | SH | Call | SOLE |  | 321000 | 0 | 0 |
| CIDARA THERAPEUTICS INC | COM NEW | 171757206 |  | 24432936 | 501600 | SH | Put | SOLE |  | 501600 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 7435090 | 1035528 | SH |  | SOLE |  | 1035528 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 1885468 | 262600 | SH | Call | SOLE |  | 262600 | 0 | 0 |
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 |  | 12465476 | 433431 | SH |  | SOLE |  | 433431 | 0 | 0 |
| CUMBERLAND PHARMACEUTICALS I | COM | 230770109 |  | 1996372 | 595932 | SH |  | SOLE |  | 595932 | 0 | 0 |
| CYBIN INC | COM NEW | 23256X407 |  | 1178585 | 140475 | SH |  | SOLE |  | 140475 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 7713651 | 233464 | SH |  | SOLE |  | 233464 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 4956000 | 150000 | SH | Call | SOLE |  | 150000 | 0 | 0 |
| DELCATH SYS INC | COM NEW | 24661P807 |  | 4384503 | 322390 | SH |  | SOLE |  | 322390 | 0 | 0 |
| DYNE THERAPEUTICS INC | COM | 26818M108 |  | 3463728 | 363837 | SH |  | SOLE |  | 363837 | 0 | 0 |
| ELEDON PHARMACEUTICALS INC | COM | 28617K101 |  | 2710599 | 1000221 | SH |  | SOLE |  | 1000221 | 0 | 0 |
| EVAXION AS | SPONSORED ADS | 29970R303 |  | 196000 | 80000 | SH |  | SOLE |  | 80000 | 0 | 0 |
| FORTE BIOSCIENCES INC | COM NEW | 34962G208 |  | 6160407 | 476443 | SH |  | SOLE |  | 476443 | 0 | 0 |
| FULCRUM THERAPEUTICS INC | COM | 359616109 |  | 2948225 | 428521 | SH |  | SOLE |  | 428521 | 0 | 0 |
| FULCRUM THERAPEUTICS INC | COM | 359616109 |  | 3673920 | 534000 | SH | Call | SOLE |  | 534000 | 0 | 0 |
| GERON CORP | COM | 374163103 |  | 2256000 | 1600000 | SH |  | SOLE |  | 1600000 | 0 | 0 |
| HOOKIPA PHARMA INC | COM NEW | 43906K209 |  | 66510 | 52996 | SH |  | SOLE |  | 52996 | 0 | 0 |
| IBIO INC | COM NEW | 451033708 |  | 457794 | 599913 | SH |  | SOLE |  | 599913 | 0 | 0 |
| IMMATICS N.V | SHS | N44445109 |  | 265750 | 49396 | SH |  | SOLE |  | 49396 | 0 | 0 |
| IMMUNIC INC | COM | 4525EP101 |  | 637633 | 914170 | SH |  | SOLE |  | 914170 | 0 | 0 |
| INFLARX NV | COM | N44821101 |  | 556958 | 705010 | SH |  | SOLE |  | 705010 | 0 | 0 |
| INHIBRX BIOSCIENCES INC | COM | 45720N103 |  | 601081 | 42122 | SH |  | SOLE |  | 42122 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 16479900 | 163751 | SH |  | SOLE |  | 163751 | 0 | 0 |
| ISHARES TR | ISHARES BIOTECH | 464287556 |  | 728065 | 5755 | SH |  | SOLE |  | 5755 | 0 | 0 |
| JANUX THERAPEUTICS INC | COM | 47103J105 |  | 2995863 | 129691 | SH |  | SOLE |  | 129691 | 0 | 0 |
| JASPER THERAPEUTICS INC | COM NEW | 471871202 |  | 139344 | 25107 | SH |  | SOLE |  | 25107 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 |  | 4244799 | 40000 | SH |  | SOLE |  | 40000 | 0 | 0 |
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 |  | 2244360 | 198528 | SH |  | SOLE |  | 198528 | 0 | 0 |
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 |  | 4522001 | 400000 | SH | Call | SOLE |  | 400000 | 0 | 0 |
| KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 |  | 117478 | 27257 | SH |  | SOLE |  | 27257 | 0 | 0 |
| KEZAR LIFE SCIENCES INC | COM NEW | 49372L209 |  | 489607 | 106901 | SH |  | SOLE |  | 106901 | 0 | 0 |
| KODIAK SCIENCES INC | COM | 50015M109 |  | 2236261 | 599534 | SH |  | SOLE |  | 599534 | 0 | 0 |
| KYMERA THERAPEUTICS INC | COM | 501575104 |  | 436400 | 10000 | SH | Put | SOLE |  | 10000 | 0 | 0 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 |  | 2211117 | 550029 | SH |  | SOLE |  | 550029 | 0 | 0 |
| LEXICON PHARMACEUTICALS INC | COM NEW | 528872302 |  | 166897 | 176479 | SH |  | SOLE |  | 176479 | 0 | 0 |
| LYELL IMMUNOPHARMA INC | COM NEW | 55083R203 |  | 387183 | 43799 | SH |  | SOLE |  | 43799 | 0 | 0 |
| LYRA THERAPEUTICS INC | COM NEW | 55234L204 |  | 189603 | 21161 | SH |  | SOLE |  | 21161 | 0 | 0 |
| MACROGENICS INC | COM | 556099109 |  | 96886 | 80071 | SH |  | SOLE |  | 80071 | 0 | 0 |
| MAZE THERAPEUTICS INC | COM | 578784100 |  | 3223819 | 262740 | SH |  | SOLE |  | 262740 | 0 | 0 |
| METSERA INC | COM | 59267L107 |  | 2199640 | 77316 | SH |  | SOLE |  | 77316 | 0 | 0 |
| MIND MEDICINE MINDMED INC | COM NEW | 60255C885 |  | 406864 | 62691 | SH |  | SOLE |  | 62691 | 0 | 0 |
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 |  | 4460400 | 94500 | SH | Call | SOLE |  | 94500 | 0 | 0 |
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 |  | 9180400 | 194500 | SH | Put | SOLE |  | 194500 | 0 | 0 |
| NEUMORA THERAPEUTICS INC. | COM | 640979100 |  | 9164 | 12498 | SH |  | SOLE |  | 12498 | 0 | 0 |
| NEURONETICS INC | COM | 64131A105 |  | 3837953 | 1099700 | SH |  | SOLE |  | 1099700 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 |  | 3745148 | 206800 | SH |  | SOLE |  | 206800 | 0 | 0 |
| NUVATION BIO INC | COM CL A | 67080N101 |  | 1207553 | 619258 | SH |  | SOLE |  | 619258 | 0 | 0 |
| NYXOAH S A | SHS | B6S7WD106 |  | 378691 | 50627 | SH |  | SOLE |  | 50627 | 0 | 0 |
| ORUKA THERAPEUTICS INC | COM | 687604108 |  | 768715 | 68574 | SH |  | SOLE |  | 68574 | 0 | 0 |
| PEPGEN INC | COM | 713317105 |  | 166500 | 150000 | SH |  | SOLE |  | 150000 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 11645747 | 276950 | SH |  | SOLE |  | 276950 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 10192920 | 242400 | SH | Call | SOLE |  | 242400 | 0 | 0 |
| PROQR THRAPEUTICS N V | SHS EURO | N71542109 |  | 1770860 | 868069 | SH |  | SOLE |  | 868069 | 0 | 0 |
| PROTHENA CORP PLC | SHS | G72800108 |  | 607000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| RELAY THERAPEUTICS INC | COM | 75943R102 |  | 2571846 | 743308 | SH |  | SOLE |  | 743308 | 0 | 0 |
| RELMADA THERAPEUTICS INC | COM | 75955J402 |  | 24174 | 40270 | SH |  | SOLE |  | 40270 | 0 | 0 |
| SAGIMET BIOSCIENCES INC | COM SER A | 786700104 |  | 91318 | 11984 | SH |  | SOLE |  | 11984 | 0 | 0 |
| SANGAMO THERAPEUTICS INC | COM | 800677106 |  | 682134 | 1260179 | SH |  | SOLE |  | 1260179 | 0 | 0 |
| SAREPTA THERAPEUTICS INC | COM | 803607100 |  | 7679388 | 449087 | SH |  | SOLE |  | 449087 | 0 | 0 |
| SAREPTA THERAPEUTICS INC | COM | 803607100 |  | 5678910 | 332100 | SH | Call | SOLE |  | 332100 | 0 | 0 |
| SCHOLAR ROCK HLDG CORP | COM | 80706P103 |  | 1741920 | 49179 | SH |  | SOLE |  | 49179 | 0 | 0 |
| SCHOLAR ROCK HLDG CORP | COM | 80706P103 |  | 3542000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| SENSEI BIOTHERAPEUTICS INC | COM NEW | 81728A207 |  | 193025 | 22497 | SH |  | SOLE |  | 22497 | 0 | 0 |
| SILENCE THERAPEUTICS PLC | ADS | 82686Q101 |  | 1397709 | 873568 | SH |  | SOLE |  | 873568 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 |  | 16756000 | 200000 | SH | Call | SOLE |  | 200000 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 |  | 16756000 | 200000 | SH | Put | SOLE |  | 200000 | 0 | 0 |
| SPRUCE BIOSCIENCES INC | COM | 85209E109 |  | 72501 | 1000000 | SH |  | SOLE |  | 1000000 | 0 | 0 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 |  | 3797183 | 183085 | SH |  | SOLE |  | 183085 | 0 | 0 |
| SYNLOGIC INC | COM NEW | 87166L209 |  | 25936 | 20422 | SH |  | SOLE |  | 20422 | 0 | 0 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 |  | 7961673 | 196536 | SH |  | SOLE |  | 196536 | 0 | 0 |
| TECTONIC THERAPEUTIC INC | COM | 878972108 |  | 3252639 | 163696 | SH |  | SOLE |  | 163696 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 218172 | 58491 | SH |  | SOLE |  | 58491 | 0 | 0 |
| TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | 881624209 |  | 3352000 | 200000 | SH | Call | SOLE |  | 200000 | 0 | 0 |
| TG THERAPEUTICS INC | COM | 88322Q108 |  | 7555669 | 209938 | SH |  | SOLE |  | 209938 | 0 | 0 |
| THERIVA BIOLOGICS INC | COM NEW | 87164U508 |  | 52070 | 120031 | SH |  | SOLE |  | 120031 | 0 | 0 |
| TOURMALINE BIO INC | COM | 89157D105 |  | 1086152 | 67927 | SH |  | SOLE |  | 67927 | 0 | 0 |
| TRAWS PHARMA INC | COM NEW | 68232V884 |  | 42170 | 28493 | SH |  | SOLE |  | 28493 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 20474316 | 563100 | SH | Call | SOLE |  | 563100 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 10908000 | 300000 | SH | Put | SOLE |  | 300000 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 |  | 1672605 | 119986 | SH |  | SOLE |  | 119986 | 0 | 0 |
| UNIQURE NV | CALL | N90064901 |  | 11152000 | 800000 | SH | Call | SOLE |  | 800000 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 9915549 | 305000 | SH |  | SOLE |  | 305000 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 224319 | 6900 | SH | Call | SOLE |  | 6900 | 0 | 0 |
| VENTYX BIOSCIENCES INC | COM | 92332V107 |  | 2070643 | 967590 | SH |  | SOLE |  | 967590 | 0 | 0 |
| VERA THERAPEUTICS INC | CL A | 92337R101 |  | 332102 | 14096 | SH |  | SOLE |  | 14096 | 0 | 0 |
| VERA THERAPEUTICS INC | CL A | 92337R101 |  | 3609392 | 153200 | SH | Call | SOLE |  | 153200 | 0 | 0 |
| VERONA PHARMA PLC | SPONSORED ADS | 925050106 |  | 13887276 | 146831 | SH |  | SOLE |  | 146831 | 0 | 0 |
| VERU INC | COM | 92536C103 |  | 829204 | 1425239 | SH |  | SOLE |  | 1425239 | 0 | 0 |
| VIGIL NEUROSCIENCE INC | COM | 92673K108 |  | 249311 | 31360 | SH |  | SOLE |  | 31360 | 0 | 0 |
| VIKING THERAPEUTICS INC | COM | 92686J106 |  | 2650001 | 100000 | SH |  | SOLE |  | 100000 | 0 | 0 |
| VIKING THERAPEUTICS INC | COM | 92686J106 |  | 9275000 | 350000 | SH | Call | SOLE |  | 350000 | 0 | 0 |
| VIR BIOTECHNOLOGY INC | COM | 92764N102 |  | 5383032 | 1068062 | SH |  | SOLE |  | 1068062 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 |  | 6569886 | 469949 | SH |  | SOLE |  | 469949 | 0 | 0 |
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 |  | 1203406 | 601703 | SH |  | SOLE |  | 601703 | 0 | 0 |
| VOYAGER THERAPEUTICS INC | COM | 92915B106 |  | 173433 | 55766 | SH |  | SOLE |  | 55766 | 0 | 0 |
| VYNE THERAPEUTICS INC | COM | 92941V308 |  | 478501 | 290000 | SH |  | SOLE |  | 290000 | 0 | 0 |
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 |  | 1047392 | 161137 | SH |  | SOLE |  | 161137 | 0 | 0 |
| ZYMEWORKS INC | COM | 98985Y108 |  | 313751 | 25000 | SH |  | SOLE |  | 25000 | 0 | 0 |

---