# EDGAR Filing Document

**Accession Number:** 0001053906
**File Stem:** 0001193125-26-215297
**Filing Date:** 2026-5
**Character Count:** 19901
**Document Hash:** d6dcbe822cf1c669b69813f84dc09e41
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-215297.hdr.sgml**: 20260508

**ACCESSION NUMBER**: 0001193125-26-215297

**CONFORMED SUBMISSION TYPE**: 4

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260430

**FILED AS OF DATE**: 20260508

**DATE AS OF CHANGE**: 20260508

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Artal Group S.A.
- **CENTRAL INDEX KEY:** 0001053906

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** N4

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960589

**BUSINESS ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
- **BUSINESS PHONE:** (352) 22.42.59-1

**MAIL ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661

**FORMER NAME:**
- **FORMER CONFORMED NAME:** ARTAL GROUP S A
- **DATE OF NAME CHANGE:** 19980128
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Westend S.A.
- **CENTRAL INDEX KEY:** 0001283968

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** N4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960588

**BUSINESS ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
- **BUSINESS PHONE:** 3522242591

**MAIL ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661

**FORMER NAME:**
- **FORMER CONFORMED NAME:** WESTEND S.A.
- **DATE OF NAME CHANGE:** 20120816

**FORMER NAME:**
- **FORMER CONFORMED NAME:** WESTEND SA
- **DATE OF NAME CHANGE:** 20040317
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Artal International S.C.A.
- **CENTRAL INDEX KEY:** 0001218180

**ORGANIZATION NAME:**

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960591

**BUSINESS ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
- **BUSINESS PHONE:** 352224259-1

**MAIL ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661

**FORMER NAME:**
- **FORMER CONFORMED NAME:** ARTAL INTERNATIONAL SCA
- **DATE OF NAME CHANGE:** 20110531

**FORMER NAME:**
- **FORMER CONFORMED NAME:** ARTAL INTERNATIONAL SA
- **DATE OF NAME CHANGE:** 20030210
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Artal Participations S.a r.l.
- **CENTRAL INDEX KEY:** 0002048403

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** N4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960592

**BUSINESS ADDRESS:**
- **STREET 1:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
- **BUSINESS PHONE:** 352224259-1

**MAIL ADDRESS:**
- **STREET 1:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Stichting Administratiekantoor Westend
- **CENTRAL INDEX KEY:** 0001460840

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** XX

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960587

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** H.J.E. WENCKEBACHWEG 252
- **CITY:** AMSTERDAM
- **PROVINCE COUNTRY:** P7
- **ZIP:** 1096 AS
- **BUSINESS PHONE:** 352-224-2591

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** H.J.E. WENCKEBACHWEG 252
- **CITY:** AMSTERDAM
- **PROVINCE COUNTRY:** P7
- **ZIP:** 1096 AS
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Artal International Management S.A.
- **CENTRAL INDEX KEY:** 0001522131

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** N4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960590

**BUSINESS ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
- **BUSINESS PHONE:** 352224259-1

**MAIL ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L-2661
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Wittouck Amaury
- **CENTRAL INDEX KEY:** 0001841311

**ORGANIZATION NAME:**

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-30111
- **FILM NUMBER:** 26960586

**MAIL ADDRESS:**
- **STREET 1:** VALLEY PARK
- **STREET 2:** 44, RUE DE LA VALLEE
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** L2661
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** LEXICON PHARMACEUTICALS, INC.
- **CENTRAL INDEX KEY:** 0001062822
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 760474169
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 2445 TECHNOLOGY FOREST BLVD.
- **STREET 2:** SUITE 1100
- **CITY:** THE WOODLANDS
- **STATE:** TX
- **ZIP:** 77381
- **BUSINESS PHONE:** 2818633000

**MAIL ADDRESS:**
- **STREET 1:** 2445 TECHNOLOGY FOREST BLVD.
- **STREET 2:** SUITE 1100
- **CITY:** THE WOODLANDS
- **STATE:** TX
- **ZIP:** 77381

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** LEXICON PHARMACEUTICALS, INC./DE
- **DATE OF NAME CHANGE:** 20070426

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** LEXICON GENETICS INC/TX
- **DATE OF NAME CHANGE:** 20000126

## Exhibit 99.1

**Exhibit 99.1**

SIGNATURE PAGE

---

| |
|:---|
| ARTAL PARTICIPATIONS S.a r.l.<br>Signature: <u>/s/ Pierre Claudel</u><br>Name/Title: Pierre Claudel, Manager<br>Date: May 8, 2026 |
| <br>ARTAL INTERNATIONAL S.C.A.<br>Signature: <u>/s/ Anne Goffard</u><br>Name/Title: Anne Goffard, Managing Director of Artal International Management S.A., its managing partner<br>Date: May 8, 2026 |

---

---

| |
|:---|
| ARTAL INTERNATIONAL MANAGEMENT S.A. <br>Signature: <u>/s/ Anne Goffard</u><br>Name/Title: Anne Goffard, Managing Director<br>Date: May 8, 2026 |
| <br>ARTAL GROUP S.A.<br>Signature: <u>/s/ Anne Goffard</u><br>Name/Title: Anne Goffard, Authorized Person<br>Date: May 8, 2026 |
| <br>WESTEND S.A.<br>Signature: <u>/s/ Anne Goffard</u><br>Name/Title: Anne Goffard, Managing Director<br>Date: May 8, 2026 |
| <br>STICHTING ADMINISTRATIEKANTOOR WESTEND<br>Signature: <u>/s/ Amaury Wittouck</u><br>Name: Amaury Wittouck, Sole Member of the Board<br>Date: May 8, 2026 |
| <br>AMAURY WITTOUCK <br>Signature: <u>/s/ Amaury Wittouck</u><br>Name: Amaury Wittouck<br>Date: May 8, 2026 |

---

------

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 4

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[ ] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Artal Participations S.a r.l.<br><sub>(Last) (First) (Middle)</sub><br>VALLEY PARK 44, RUE DE LA VALLEE<br><sub>(Street)</sub><br>LUXEMBOURG, LUXEMBOURG L-2661<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Artal International S.C.A.<br><sub>(Last) (First) (Middle)</sub><br>VALLEY PARK, 44, RUE DE LA VALLEE<br><sub>(Street)</sub><br>LUXEMBOURG, LUXEMBOURG L-2661<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Artal International Management S.A.<br><sub>(Last) (First) (Middle)</sub><br>VALLEY PARK, 44, RUE DE LA VALLEE<br><sub>(Street)</sub><br>LUXEMBOURG, LUXEMBOURG L-2661<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Artal Group S.A.<br><sub>(Last) (First) (Middle)</sub><br>VALLEY PARK, 44, RUE DE LA VALLEE<br><sub>(Street)</sub><br>LUXEMBOURG, LUXEMBOURG L-2661<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Westend S.A.<br><sub>(Last) (First) (Middle)</sub><br>VALLEY PARK, 44, RUE DE LA VALLEE<br><sub>(Street)</sub><br>LUXEMBOURG, LUXEMBOURG L-2661<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Stichting Administratiekantoor Westend<br><sub>(Last) (First) (Middle)</sub><br>H.J.E. WENCKEBACHWEG 252<br><sub>(Street)</sub><br>AMSTERDAM, NETHERLANDS 1096 AS<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Wittouck Amaury<br><sub>(Last) (First) (Middle)</sub><br>VALLEY PARK, 44, RUE DE LA VALLEE<br><sub>(Street)</sub><br>LUXEMBOURG, LUXEMBOURG L-2661<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2026-04-30 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>LEXICON PHARMACEUTICALS, INC. [ LXRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Common Stock | 2026-04-30 |  | M<sup>(1)</sup> |  | 20421735.00 | A | $0 | 175156062 | I | See Footnotes<sup>(2)(3)(4)</sup> |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| Series B Convertible Preferred Stock | <sup>(1)</sup> | 2026-04-30 |  | A |  | 408434.70 |  | <sup>(1)</sup> | <sup>(1)</sup> | Common Stock | 20421735.00 | <sup>(1)</sup> | 408434.70 | I | See Footnotes<sup>(2)(3)(4)</sup> |
| Series B Convertible Preferred Stock | <sup>(1)</sup> | 2026-04-30 |  | M |  |  | 408434.70 | <sup>(1)</sup> | <sup>(1)</sup> | Common Stock | 20421735.00 | $0 | 0 | I | See Footnotes<sup>(2)(3)(4)</sup> |

---

### Footnotes:

(1) Pursuant to the terms of a Preferred Stock Purchase Agreement, dated as of January 29, 2026, Artal Participations S.a r.l. acquired an aggregate of 408,434.70 shares of Series B convertible preferred stock, $0.01 par value per share (the "Preferred Stock") of the Issuer at a price of $65.00 per share. Each share of Preferred Stock would automatically convert into 50 shares of the Issuer's common stock, par value $0.001 per share (the "Common Stock") upon receipt of shareholder approval and the satisfaction of certain other conditions (the "Conditions"); however, absent the satisfaction of such conditions, the shares were not convertible, and as such, the Preferred Stock was originally reported on Table I. On April 30, 2026, all Conditions were met, and the 408,434.70 shares of Preferred Stock became derivative securities and automatically converted into 20,421,735 shares of Issuer Common Stock.

(2) These securities are directly held by Artal Participations S.a r.l.

(3) The sole shareholder of Artal Participations S.a r.l. is Artal International S.C.A. The managing partner of Artal International S.C.A. is Artal International Management S.A. The sole stockholder of Artal International Management S.A. is Artal Group S.A. The parent company of Artal Group S.A. is Westend S.A. The majority stockholder of Westend S.A. is Stichting Administratiekantoor Westend (the "Stichting"). Mr. Amaury Wittouck is the sole member of the board of the Stichting.

(4) Each of the Reporting Persons (other than to the extent it directly holds securities reported herein) disclaims beneficial ownership of the securities held by the other Reporting Persons, except to the extent of such Reporting Person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), each of the Reporting Persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Exchange Act or for any other purpose.

**Remarks:**
Invus Public Equities, L.P. directly holds 7,362,368 shares of Common Stock, Invus, L.P. directly owns 35,402,689 shares of Common Stock, Invus US Partners LLC directly owns 5,451,204 shares of Common Stock, Mr. Debbane directly owns 1,906,186 shares of Common Stock, Avicenna Life Sci Master Fund LP directly owns 1,538,462 shares of Common Stock and Artal Participations S.a r.l. directly owns 175,156,062 shares of Common Stock, which securities are reported on separate Form 4 filings. For purposes of Section 16 of the Exchange Act, the Reporting Persons may be deemed to be directors by deputization of the Issuer by virtue of Invus, L.P.'s right to designate certain members of the Issuer's board of directors pursuant to a stockholders' agreement between the Issuer and Invus, L.P.

**Signature:** See Exhibit 99.1  
**Date:** 2026-05-08

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**