# EDGAR Filing Document

**Accession Number:** 0001746382
**File Stem:** 0001387131-23-001993
**Filing Date:** 2023-2
**Character Count:** 21124
**Document Hash:** c8d1c671a5bcfed167c4661cecad8059
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001387131-23-001993.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0001387131-23-001993

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20230214

**DATE AS OF CHANGE**: 20230214

**GROUP MEMBERS**: ALTIUM GROWTH FUND, LP

**GROUP MEMBERS**: ALTIUM GROWTH GP, LLC

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PALISADE BIO, INC.
- **CENTRAL INDEX KEY:** 0001357459
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 522007292
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-86724
- **FILM NUMBER:** 23625534

**BUSINESS ADDRESS:**
- **STREET 1:** 7750 EL CAMINO REAL, SUITE 5200
- **CITY:** CARLSBAD
- **STATE:** CA
- **ZIP:** 92009
- **BUSINESS PHONE:** (858) 704-4900

**MAIL ADDRESS:**
- **STREET 1:** 7750 EL CAMINO REAL, SUITE 5200
- **CITY:** CARLSBAD
- **STATE:** CA
- **ZIP:** 92009

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Seneca Biopharma, Inc.
- **DATE OF NAME CHANGE:** 20200127

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Neuralstem, Inc.
- **DATE OF NAME CHANGE:** 20060324
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Altium Capital Management LP
- **CENTRAL INDEX KEY:** 0001746382
- **IRS NUMBER:** 822066653
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** 152 W 57 ST FL20
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019
- **BUSINESS PHONE:** 2124842711

**MAIL ADDRESS:**
- **STREET 1:** 152 W 57 ST FL20
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**SCHEDULE 13G/A**

**Under the Securities Exchange Act of 1934**

**(Amendment No. 1)\***

**Palisade Bio, Inc.**

(Name of Issuer)

**Common Stock, par value $0.01 per share**

(Title of Class of Securities)

**696389204** 

(CUSIP Number)

**December 31, 2022**

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b) <br> ☒ Rule 13d-1(c) <br> ☐ Rule 13d-1(d)

\* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Page 2 of **9**

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| | | |
|:---|:---|:---|
| **CUSIP No**. | **696389204** | <u> </u> |

---

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| | | | | |
|:---|:---|:---|:---|:---|
| **1** | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Capital Management, LP<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2066653 | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Capital Management, LP<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2066653 | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Capital Management, LP<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2066653 |  |
| **2** | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | (a) ☐<br> (b) ☒ |
| **3** | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY |  |
| **4** | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **5** | SOLE VOTING <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **6** | SHARED VOTING POWER <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **7** | SOLE DISPOSITIVE POWER <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **8** | SHARED DISPOSITIVE POWER <br> 0  |  |
| **9** | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  |  |
| **10** | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | ☐ |
| **11** | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% |  |
| **12** | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> IA, PN  | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> IA, PN  | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> IA, PN  |  |

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Page 3 of **9**

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| | |
|:---|:---|
| **CUSIP No**. | **696389204** |

---

---

| | | | | |
|:---|:---|:---|:---|:---|
| **1** | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Growth Fund, LP<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2105101 | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Growth Fund, LP<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2105101 | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Growth Fund, LP<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2105101 |  |
| **2** | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | (a) ☐<br> (b) ☒ |
| **3** | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY |  |
| **4** | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **5** | SOLE VOTING <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **6** | SHARED VOTING POWER <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **7** | SOLE DISPOSITIVE POWER <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **8** | SHARED DISPOSITIVE POWER <br> 0  |  |
| **9** | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  |  |
| **10** | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | ☐ |
| **11** | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% |  |
| **12** | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> PN  | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> PN  | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> PN  |  |

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Page 4 of **9**

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| | |
|:---|:---|
| **CUSIP No**. | **696389204** |

---

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| | | | | |
|:---|:---|:---|:---|:---|
| **1** | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Growth GP, LLC<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2086430 | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Growth GP, LLC<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2086430 | &nbsp;&nbsp;NAME OF REPORTING PERSONS<br> Altium Growth GP, LLC<br>I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS<br> (ENTITIES ONLY) EIN: 82-2086430 |  |
| **2** | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | (a) ☐<br> (b) ☒ |
| **3** | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY |  |
| **4** | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America | &nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware, United States of America |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **5** | SOLE VOTING <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **6** | SHARED VOTING POWER <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **7** | SOLE DISPOSITIVE POWER <br> 0  |  |
| NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON<br> WITH: | **8** | SHARED DISPOSITIVE POWER <br> 0  |  |
| **9** | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  | &nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON <br> 0  |  |
| **10** | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES | ☐ |
| **11** | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% | &nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 <br> 0% |  |
| **12** | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> OO  | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> OO  | &nbsp;&nbsp;TYPE OF REPORTING PERSON <br> OO  |  |

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Page 5 of **9**

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| | |
|:---|:---|
| **CUSIP No.** | **696389204** |

---

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| | | |
|:---|:---|:---|
| **Item 1(a).** |  | **Name of Issuer:** Palisade Bio, INC. (the "Issuer") |
| **Item 1(b).** |  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Address of Issuer's Principal Executive Offices:** 7750 El Camino Real, Suite 5200 <br> Carlsbad, California 92009  |
| **Item 2(a).** |  | **Name of Person Filing:** <br> This statement is jointly filed by and on behalf of each of Altium Growth Fund, LP (the "Fund"), Altium Capital Management, LP, and Altium Growth GP, LLC. The Fund is the record and direct beneficial owner of the securities covered by this statement. Altium Capital Management, LP is the investment adviser of, and may be deemed to beneficially own securities, owned by, the Fund. Altium Growth GP, LLC is the general partner of, and may be deemed to beneficially own securities owned by, the Fund. <br>Each reporting person declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, the beneficial owner of any securities covered by this statement. <br>Each of the reporting persons may be deemed to be a member of a group with respect to the Issuer or securities of the Issuer for the purposes of Section 13(d) or 13(g) of the Act. Each of the reporting persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate, or other group for the purpose of acquiring, holding, or disposing of securities of the Issuer or otherwise with respect to the Issuer or any securities of the Issuer or (ii) a member of any group with respect to the Issuer or any securities of the Issuer.  |
| **Item 2(b).** |  | **Address of Principal Business Office or, if None, Residence:** |
|  |  | The address of the principal business office of each of the reporting persons is<br> 152 West 57th Street, FL 20, New York, NY 10019 |
| **Item 2(c).** |  | **Citizenship:** |
|  |  | See Item 4 on the cover page(s) hereto. |
| **Item 2(d).** |  | **Title of Class of Securities:** |
|  |  | Common Stock, par value $0.01 per share ("Common Stock") |
| **Item 2(e).** |  | **CUSIP Number:** 696389204 |
| **Item 3.** | **If This Statement is Filed Pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), Check Whether the Person Filing is a:** | **If This Statement is Filed Pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), Check Whether the Person Filing is a:** |
|  | (a) | Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o). |
|  | (b) | Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c). |

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Page 6 of **9**

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| | |
|:---|:---|
| **CUSIP No.** | **696389204** |

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(c) ☐ Insurance company as defined in Section 3(a)(19) of the
 Act (15 U.S.C. 78c).

(d) ☐ Investment company registered under Section 8 of the Investment Company Act
 of 1940 (15 U.S.C. 80a-8).

(e) ☐ An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

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| | | | |
|:---|:---|:---|:---|
|  | (f) | ☐ | An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F); |
|  | (g) | ☐ | A parent holding company or control person in accordance with §240.13d-1(b)(ii)(G); |
|  | (h) | ☐ | A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813); |
|  | (i) | ☐ | A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act (15 U.S.C. 80a-3); |
|  | (j) | ☐ | Group, in accordance with §240.13d-1(b)(1)(ii)(J). |
| **Item 4.** | **Ownership.** | **Ownership.** | **Ownership.** |
|  | <br>Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. <br>As of the Reporting Date the Firm does not control any shares of the Issuer.  | <br>Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. <br>As of the Reporting Date the Firm does not control any shares of the Issuer.  | <br>Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. <br>As of the Reporting Date the Firm does not control any shares of the Issuer.  |

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Page 7 of **9**

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| | |
|:---|:---|
| **CUSIP No** . | **696389204** |

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| | |
|:---|:---|
| **Item 5.** | **Ownership of Five Percent or Less of a Class.** |
|  | If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ☒ |
| **Item 6.** | **Ownership of More than Five Percent on Behalf of Another Person.** |
|  | Not applicable |
| **Item 7.** | **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.** |
|  | Not applicable |
| **Item 8.** | **Identification and Classification of Members of the Group.** |
|  | Not applicable |
| **Item 9.** | **Notice of Dissolution of Group.** |
|  | Not applicable |
| **Item 10.** | **Certification.** |

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By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

---

| | |
|:---|:---|
| Dated: | February 14, 2023 |
| **Altium Capital Management, LP** | **Altium Capital Management, LP** |
| By: | /s/ Jacob Gottlieb |
| Name: | Jacob Gottlieb |
| Title: | CEO |
| **Altium Growth Fund, LP** | **Altium Growth Fund, LP** |
| By: Altium Growth GP, LLC | By: Altium Growth GP, LLC |
| Its: General Partner | Its: General Partner |
| Signature: | /s/ Jacob Gottlieb |
| Name: | Jacob Gottlieb |
| Title: | Managing Member of Altium Growth GP, LLC |
| **Altium Growth GP, LLC** | **Altium Growth GP, LLC** |
| By: | /s/ Jacob Gottlieb |
| Name: | Jacob Gottlieb |
| Title: | Managing Member |

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Page 8 of **9**

EXHIBIT INDEX

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| | |
|:---|:---|
| [EXHIBIT 1](ex-1.htm): | Joint Acquisition Statement Pursuant to Section 240.13d-1(k) |
|  | Members of Group |

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## Ex-1

[Palisade Bio, Inc. SC 13GA](pali-sc13ga_123122.htm)

Page 9 of **9**

EXHIBIT 1

JOINT ACQUISITION STATEMENT

<u>PURSUANT TO SECTION 240.13d-1(k)</u>

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint acquisition statements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him, her or it contained therein, but shall not be responsible for the completeness and accuracy of the information concerning the other entities or persons, except to the extent that he, she or it knows or has reason to believe that such information is inaccurate.

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| | |
|:---|:---|
| Dated: | February 14, 2023 |
| **Altium Capital Management, LP** | **Altium Capital Management, LP** |
| By: | /s/ Jacob Gottlieb |
| Name: | Jacob Gottlieb |
| Title: | CEO |
| **Altium Growth Fund, LP** | **Altium Growth Fund, LP** |
| By: Altium Growth GP, LLC | By: Altium Growth GP, LLC |
| Its: General Partner | Its: General Partner |
| Signature: | /s/ Jacob Gottlieb |
| Name: | Jacob Gottlieb |
| Title: | Managing Member of Altium Growth GP, LLC |
| **Altium Growth GP, LLC** | **Altium Growth GP, LLC** |
| By: | /s/ Jacob Gottlieb |
| Name: | Jacob Gottlieb |
| Title: | Managing Member |

---