# EDGAR Filing Document

**Accession Number:** 0001424958
**File Stem:** 0001193125-25-333792
**Filing Date:** 2025-12
**Character Count:** 54021
**Document Hash:** 111696af20e9567eb2f522d8721e7460
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-333792.hdr.sgml**: 20251229

**ACCESSION NUMBER**: 0001193125-25-333792

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20251031

**FILED AS OF DATE**: 20251229

**DATE AS OF CHANGE**: 20251229

**PERIOD START**: 20251031

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Direxion Shares ETF Trust
- **CENTRAL INDEX KEY:** 0001424958

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1031

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-22201
- **FILM NUMBER:** 251605888

**BUSINESS ADDRESS:**
- **STREET 1:** 535 MADISON AVENUE
- **STREET 2:** 37TH FL.
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022
- **BUSINESS PHONE:** 646-572-3390

**MAIL ADDRESS:**
- **STREET 1:** 535 MADISON AVENUE
- **STREET 2:** 37TH FL.
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Direxion ETF Trust
- **DATE OF NAME CHANGE:** 20080124

## Series and Classes Contracts Data

### Direxion Daily S&P Biotech Bull 3X Shares (Series ID: S000049373)

| Class ID   | Class Name                                | Ticker Symbol   |
|:---|:---|:---|
| C000156149 | Direxion Daily S&P Biotech Bull 3X Shares | LABU            |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** Direxion Shares ETF Trust

- **b. Investment Company Act file number:** 811-22201

- **c. CIK number of Registrant:** 0001424958

- **d. LEI of Registrant:** 549300M501IVJM50FG12

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 1301 Avenue of the Americas (6th Avenue)

  - **City:** New York

  - **State:** NY

  - **Foreign country:** US

  - **Zip / Postal Code:** 10019

  - **Telephone number:** 646-572-3390

**Item A.2. Information about the Series.**

- **a. Name of Series:** Direxion Daily S&P Biotech Bull 3X Shares

- **b. EDGAR series identifier (if any):** S000049373

- **c. LEI of Series:** 549300WNBLZ8IWC9IW36

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-10-31

- **b. Date as of which information is reported:** 2025-10-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $1227611875.19

**Total Liabilities:** $410506151.86

**Net Assets:** $817105723.33

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000156149 | 13.39%               | 35.56%               | 40.00%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $15436125.05             | $7399079.56                                |
| Month 2  | $20600009.14             | $27158763.52                               |
| Month 3  | $22581947.22             | $28983079.22                               |

### Schedule of Portfolio Investments

| Name                                | Title                                                               | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Adma Biologics Inc                  | Adma Biologics Inc COM USD0.0001                                    | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    396556 | NS      | $6138686.88   | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| aTyr Pharma Inc                     | ATYR PHARMA INC                                                     | CUSIP: 002120202<br>LEI: 529900ENQUXMC5EBKO36 | Long             | EC               | CORP              | US        |    189964 | NS      | $164508.82    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| AbbVie Inc.                         | AbbVie Inc. COM USD0.01                                             | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |     42351 | NS      | $9234212.04   | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Acadia Pharmaceuticals Inc          | Acadia Pharmaceuticals Inc COM USD0.0001                            | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |    217155 | NS      | $4929418.50   | 0.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc              | SPYRE THERAPEUTICS INC                                              | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |     66433 | NS      | $1624951.18   | 0.20%             |  |  |  | No            |                  1 | On Loan: —       |
| Agios Pharmaceuticals Inc           | Agios Pharmaceuticals Inc COM USD0.001                              | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     75954 | NS      | $3284250.96   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Akebia Therapeutics Inc.            | AKEBIA THERAPEUTICS INC                                             | CUSIP: 00972D105<br>LEI: 549300CBQEHMKEEGNX42 | Long             | EC               | CORP              | US        |    536538 | NS      | $1185748.98   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Akero Therapeutics Inc              | Akero Therapeutics Inc COM USD0.0001                                | CUSIP: 00973Y108<br>LEI: 549300SI3KG74LBE2955 | Long             | EC               | CORP              | US        |    150133 | NS      | $8137208.60   | 1.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc.        | Alnylam Pharmaceuticals Inc. COM USD0.01                            | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |     19099 | NS      | $8709907.96   | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc.                      | ALTIMMUNE INC                                                       | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |    173909 | NS      | $704331.45    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc.                          | Amgen Inc. COM USD0.0001                                            | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |     32182 | NS      | $9604074.26   | 1.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Amicus Therapeutics Inc.            | Amicus Therapeutics Inc. COM STK USD0.01                            | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |    421694 | NS      | $3807896.82   | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| AnaptysBio Inc.                     | ANAPTYSBIO INC                                                      | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |     33500 | NS      | $1225430.00   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp.          | Anavex Life Sciences Corp. USD0.001                                 | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |    120731 | NS      | $962226.07    | 0.12%             |  |  |  | No            |                  1 | On Loan: —       |
| Apellis Pharmaceuticals Inc         | Apellis Pharmaceuticals Inc COM USD0.0001                           | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |    187449 | NS      | $4024530.03   | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc.            | APOGEE THERAPEUTICS INC                                             | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     73259 | NS      | $4145726.81   | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp.             | ARBUTUS BIOPHARMA CORP                                              | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | CA        |     59020 | NS      | $279164.60    | 0.03%             |  |  |  | No            |                  1 | On Loan: —       |
| Arcellx Inc                         | Arcellx Inc COMMON STOCK                                            | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     54825 | NS      | $4947956.25   | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardelyx Inc                         | ARDELYX INC                                                         | CUSIP: 039697107<br>LEI: 549300F542QR4SXHCY32 | Long             | EC               | CORP              | US        |    350491 | NS      | $2123975.46   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcus Biosciences Inc.              | Arcus Biosciences Inc. COM USD0.0001                                | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     77554 | NS      | $1529364.88   | 0.19%             |  |  |  | No            |                  1 | On Loan: —       |
| Arcutis Biotherapeutics Inc.        | ARCUTIS BIOTHERAPEUTICS INC                                         | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    165120 | NS      | $4179187.20   | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcturus Therapeutics Holdings Inc  | Arcturus Therapeutics Holdings Inc COM                              | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     40144 | NS      | $400235.68    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| ArriVent BioPharma Inc.             | ARRIVENT BIOPHARMA INC                                              | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     38258 | NS      | $716572.34    | 0.09%             |  |  |  | No            |                  1 | On Loan: —       |
| Arrowhead Pharmaceuticals Inc       | Arrowhead Pharmaceuticals Inc COM USD0.001                          | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |    127359 | NS      | $5398748.01   | 0.66%             |  |  |  | No            |                  1 | On Loan: —       |
| Avidity Biosciences Inc.            | Avidity Biosciences Inc. COM                                        | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    193161 | NS      | $13492295.85  | 1.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc.              | Beam Therapeutics Incorporation COM                                 | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    152709 | NS      | $3819252.09   | 0.47%             |  |  |  | No            |                  1 | On Loan: —       |
| BioCryst Pharmaceuticals Inc.       | BioCryst Pharmaceuticals Inc. COM USD0.01                           | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    411223 | NS      | $3010152.36   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Biomarin Pharmaceutical Inc.        | Biomarin Pharmaceutical Inc. COM USD0.001                           | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |    164458 | NS      | $8810015.06   | 1.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                          | Biogen Inc COM USD0.0005                                            | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |     62845 | NS      | $9695098.15   | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Bridgebio Pharma Inc                | Bridgebio Pharma Inc COM USD0.001                                   | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |    169233 | NS      | $10600755.12  | 1.30%             |  |  |  | No            |                  1 | On Loan: —       |
| Caredx Inc                          | Caredx Inc COM USD0.001                                             | CUSIP: 14167L103<br>LEI: 549300NQOFKL9NON0U06 | Long             | EC               | CORP              | US        |    102994 | NS      | $1544910.00   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc.       | Catalyst Pharmaceuticals Inc. COM STK USD0.001                      | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |    174861 | NS      | $3719293.47   | 0.46%             |  |  |  | No            |                  1 | On Loan: No      |
| Celcuity Inc.                       | CELCUITY INC                                                        | CUSIP: 15102K100<br>LEI: 25490070W7UU7W2SEY87 | Long             | EC               | CORP              | US        |      8972 | NS      | $692279.52    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc.           | Celldex Therapeutics Inc. COM USD0.001(POST REV SPLT                | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |    108519 | NS      | $2900712.87   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| CG Oncology Inc.                    | CG ONCOLOGY INC                                                     | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     68684 | NS      | $2971956.68   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Cidara Therapeutics Inc             | CIDARA THERAPEUTICS INC                                             | CUSIP: 171757206<br>LEI: 549300IHQ9Z7RI1X2D22 | Long             | EC               | CORP              | US        |     35046 | NS      | $3828425.04   | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences Inc.             | Cogent Biosciences Inc. COM                                         | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    165681 | NS      | $2700600.30   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Compass Therapeutics Inc            | COMPASS THERAPEUTICS INC                                            | CUSIP: 20454B104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     79009 | NS      | $295493.66    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc           | CULLINAN ONCOLOGY INC                                               | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45352 | NS      | $392748.32    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                    | Cytokinetics Inc COM USD0.001                                       | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |    113621 | NS      | $7225159.39   | 0.88%             |  |  |  | No            |                  1 | On Loan: —       |
| Day One Biopharmaceuticals Inc.     | Day One Biopharmaceuticals Inc. COM                                 | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    142053 | NS      | $1056874.32   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc             | Denali Therapeutics Inc COM USD0.01                                 | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |    203633 | NS      | $3315145.24   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc           | DIANTHUS THERAPEUTICS INC                                           | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |     19298 | NS      | $675044.04    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Disc Medicine Inc                   | DISC MEDICINE INC                                                   | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     41534 | NS      | $3581061.48   | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Dynavax Technologies Corp.          | Dynavax Technologies Corp. COM USD0.001                             | CUSIP: 268158201<br>LEI: 549300T5URIXWDILX594 | Long             | EC               | CORP              | US        |    182831 | NS      | $1875846.06   | 0.23%             |  |  |  | No            |                  1 | On Loan: —       |
| Dyne Therapeutics Inc.              | DYNE THERAPEUTICS INC                                               | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    237400 | NS      | $5360492.00   | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| 89bio Inc.                          | 89BIO INC                                                           | CUSIP: 282559103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |         0 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Emergent Biosolutions Inc           | EMERGENT BIOSOLUTIONS INC                                           | CUSIP: 29089Q105<br>LEI: 549300YW6TUOX8BE5103 | Long             | EC               | CORP              | US        |    104913 | NS      | $1309314.24   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corporation          | Exact Sciences Corporation COM USD0.01                              | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |    163641 | NS      | $10585936.29  | 1.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Exelixis, Inc.                      | Exelixis, Inc. COM USD0.001                                         | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |    237737 | NS      | $9193289.79   | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Geron Corp.                         | Geron Corp. COM USD0.001                                            | CUSIP: 374163103<br>LEI: 549300T282D7Z2YESL90 | Long             | EC               | CORP              | US        |   1098253 | NS      | $1383798.78   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc.                | Gilead Sciences, Inc. COM USD0.001                                  | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |     77763 | NS      | $9315229.77   | 1.14%             |  |  |  | No            |                  1 | On Loan: No      |
| GRAIL Inc                           | GRAIL INC                                                           | CUSIP: 384747101<br>LEI: 2549009XSNESW3VE8024 | Long             | EC               | CORP              | US        |     47887 | NS      | $4402251.91   | 0.54%             |  |  |  | No            |                  1 | On Loan: —       |
| Halozyme Therapeutics Inc           | Halozyme Therapeutics Inc COM USD0.001                              | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |    118244 | NS      | $7708326.36   | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEAYA Biosciences Inc.             | IDEAYA Biosciences Inc. COM USD0.0001                               | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |    103725 | NS      | $3304678.50   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| ImmunityBio Inc                     | IMMUNITYBIO INC                                                     | CUSIP: 45256X103<br>LEI: 529900J9XLBR4HFL4B83 | Long             | EC               | CORP              | US        |    503788 | NS      | $1209091.20   | 0.15%             |  |  |  | No            |                  1 | On Loan: —       |
| Immunome Inc                        | IMMUNOME INC                                                        | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96297 | NS      | $1547492.79   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant Inc                      | Immunovant Inc COM                                                  | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113423 | NS      | $2799279.64   | 0.34%             |  |  |  | No            |                  1 | On Loan: —       |
| Incyte Corporation.                 | Incyte Corporation. COM USD0.001                                    | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |    103918 | NS      | $9714254.64   | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                          | Insmed Inc COM USD0.01                                              | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |     61414 | NS      | $11644094.40  | 1.43%             |  |  |  | No            |                  1 | On Loan: No      |
| INHIBRX INC CVR                     | INHIBRX INC CVR                                                     | CUSIP: 457CVR017<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    164173 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Intellia Therapeutics Inc           | Intellia Therapeutics Inc COM USD0.0001                             | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |    203864 | NS      | $2572763.68   | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals, Inc.         | Ionis Pharmaceuticals, Inc. COM USD0.001                            | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |    140041 | NS      | $10405046.30  | 1.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics Inc         | Iovance Biotherapeutics Inc COM USD0.000041666                      | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |    537764 | NS      | $1059395.08   | 0.13%             |  |  |  | No            |                  1 | On Loan: —       |
| Janux Therapeutics Inc              | JANUX THERAPEUTICS INC                                              | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     84844 | NS      | $2435871.24   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals Inc.       | KALVISTA PHARMACEUTICALS INC                                        | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |     64342 | NS      | $701971.22    | 0.09%             |  |  |  | No            |                  1 | On Loan: —       |
| Keros Therapeutics Inc.             | Keros Therapeutics Inc. COM                                         | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49069 | NS      | $746830.18    | 0.09%             |  |  |  | No            |                  1 | On Loan: —       |
| Krystal Biotech Inc                 | Krystal Biotech Inc COM USD0.00001                                  | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |     38569 | NS      | $7617763.19   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology Inc.                  | Kura Oncology Incorporation COM USD0.0001                           | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |    126068 | NS      | $1294718.36   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc             | Kymera Therapeutics Inc COM                                         | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     76044 | NS      | $4702560.96   | 0.58%             |  |  |  | No            |                  1 | On Loan: —       |
| Madrigal Pharmaceuticals Inc        | Madrigal Pharmaceuticals Inc USD0.0001                              | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |     20839 | NS      | $8729457.10   | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Mannkind Corporation                | Mannkind Corporation COM USD0.01                                    | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |    233191 | NS      | $1303537.69   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Metsera Inc.                        | METSERA INC                                                         | CUSIP: 59267L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    115205 | NS      | $7262523.20   | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| MiMedx Group Inc.                   | MiMedx Group Inc. COM USD0.001                                      | CUSIP: 602496101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     73753 | NS      | $564210.45    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Mineralys Therapeutics Inc.         | MINERALYS THERAPEUTICS INC                                          | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     35279 | NS      | $1441499.94   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharmaceuticals Inc.          | Mirum Pharmaceuticals Inc. COM USD0.0001                            | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |     36887 | NS      | $2679840.55   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                         | Moderna Inc COM USD0.0001                                           | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |    368681 | NS      | $10013375.96  | 1.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Myriad Genetics Inc.                | Myriad Genetics Inc. COM USD0.01                                    | CUSIP: 62855J104<br>LEI: 52990044IHUOUMETT163 | Long             | EC               | CORP              | US        |    125577 | NS      | $1009639.08   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc.                         | Natera Incorporation COM USD0.0001                                  | CUSIP: 632307104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     52789 | NS      | $10501315.77  | 1.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc          | Neurocrine Biosciences Inc COM USD0.001                             | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |     63453 | NS      | $9087104.13   | 1.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Novavax Inc                         | NOVAVAX INC                                                         | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |    287809 | NS      | $2417595.60   | 0.30%             |  |  |  | No            |                  1 | On Loan: —       |
| Nuvalent Inc                        | NUVALENT INC                                                        | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     53423 | NS      | $5305972.36   | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics Inc.             | NURIX THERAPEUTICS INC                                              | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    102932 | NS      | $1331940.08   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc.                         | OmniAb Inc. USD0.0001 A (USD12.5 VESTING)                           | CUSIP: 68218J202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     14783 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc.                         | OmniAb Inc. USD0.0001 A (USD15 VESTING)                             | CUSIP: 68218J301<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     14783 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC Pharmaceuticals Inc.           | ORIC PHARMACEUTICALS INC                                            | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |     95297 | NS      | $1254108.52   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics Inc              | ORUKA THERAPEUTICS INC                                              | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |     14234 | NS      | $400971.78    | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| PTC Therapeutics, Inc.              | PTC Therapeutics, Inc. COM USD0.001                                 | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |    112457 | NS      | $7681937.67   | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc      | PRAXIS PRECISION MEDICINES I                                        | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     41838 | NS      | $8315720.88   | 1.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Precigen Inc                        | PRECIGEN INC                                                        | CUSIP: 74017N105<br>LEI: 549300XCWNQU35K64G19 | Long             | EC               | CORP              | US        |    114379 | NS      | $473529.06    | 0.06%             |  |  |  | No            |                  1 | On Loan: —       |
| Protagonist Therapeutics Inc        | Protagonist Therapeutics Inc COM USD0.00001                         | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     83313 | NS      | $6550068.06   | 0.80%             |  |  |  | No            |                  1 | On Loan: —       |
| Recursion Pharmaceuticals Inc       | Recursion Pharmaceuticals Inc CL A                                  | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    835300 | NS      | $4610856.00   | 0.56%             |  |  |  | No            |                  1 | On Loan: —       |
| Regeneron Pharmaceuticals, Inc.     | Regeneron Pharmaceuticals, Inc. COM USD0.001                        | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |     16122 | NS      | $10508319.60  | 1.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Regenxbio Inc.                      | REGENXBIO INC                                                       | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |     73334 | NS      | $936475.18    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc              | Relay Therapeutics Inc COM                                          | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    168773 | NS      | $1205039.22   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc                 | REPLIMUNE GROUP INC                                                 | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |    120911 | NS      | $1176464.03   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Revolution Medicines Inc            | Revolution Medicines Inc COM                                        | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |    200237 | NS      | $11781945.08  | 1.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                        | REZOLUTE INC                                                        | CUSIP: 76200L309<br>LEI: 549300T05L48T72P2G08 | Long             | EC               | CORP              | US        |     58888 | NS      | $548836.16    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc          | Rhythm Pharmaceuticals Inc COM USD0.001                             | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |     62055 | NS      | $7059376.80   | 0.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Rigel Pharmaceuticals Inc.          | RIGEL PHARMACEUTICALS INC                                           | CUSIP: 766559702<br>LEI: 529900KPTNUS5J8K9K66 | Long             | EC               | CORP              | US        |     15230 | NS      | $480963.40    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc              | SANA BIOTECHNOLOGY INC                                              | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    298387 | NS      | $1477015.65   | 0.18%             |  |  |  | No            |                  1 | On Loan: —       |
| Sarepta Therapeutics Inc            | Sarepta Therapeutics Inc COM USD0.0001                              | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |    195005 | NS      | $4682070.05   | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| Scholar Rock Holding Corp.          | SCHOLAR ROCK HOLDING CORP                                           | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |    157454 | NS      | $4663787.48   | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| ARS Pharmaceuticals Inc             | ARS PHARMACEUTICALS INC                                             | CUSIP: 82835W108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    136303 | NS      | $1221274.88   | 0.15%             |  |  |  | No            |                  1 | On Loan: —       |
| Soleno Therapeutics Inc             | SOLENO THERAPEUTICS INC                                             | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |    102967 | NS      | $6915263.72   | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc              | STOKE THERAPEUTICS INC                                              | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |     39339 | NS      | $1181743.56   | 0.14%             |  |  |  | No            |                  1 | On Loan: —       |
| Summit Therapeutics Inc.            | SUMMIT THERAPEUTICS INC                                             | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    377653 | NS      | $7141418.23   | 0.87%             |  |  |  | No            |                  1 | On Loan: —       |
| Syndax Pharmaceuticals Inc.         | Syndax Pharmaceuticals Inc. COM USD0.0001                           | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |    157911 | NS      | $2163380.70   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics Inc.             | TANGO THERAPEUTICS INC                                              | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    161800 | NS      | $1312198.00   | 0.16%             |  |  |  | No            |                  1 | On Loan: —       |
| Taysha Gene Therapies Inc.          | TAYSHA GENE THERAPIES INC                                           | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    266989 | NS      | $1324265.44   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| TG Therapeutics Inc                 | TG Therapeutics Inc COM USD0.001                                    | CUSIP: 88322Q108<br>LEI: 529900X21UKABN9NJ529 | Long             | EC               | CORP              | US        |    236114 | NS      | $8212044.92   | 1.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Travere Therapeutics Inc            | Travere Therapeutics Inc COM                                        | CUSIP: 89422G107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    100488 | NS      | $3533158.08   | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corporation        | Twist Bioscience Corporation COM USD0.00001                         | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |    127229 | NS      | $4184561.81   | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceuticals Inc      | Ultragenyx Pharmaceuticals Inc COM USD0.001                         | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |    174233 | NS      | $6028461.80   | 0.74%             |  |  |  | No            |                  1 | On Loan: No      |
| United Therapeutics Corporation     | United Therapeutics Corporation COM USD0.01                         | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |     22609 | NS      | $10070726.87  | 1.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Upstream Bio Inc                    | UPSTREAM BIO INC                                                    | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     38438 | NS      | $993622.30    | 0.12%             |  |  |  | No            |                  1 | On Loan: —       |
| Vaxcyte Inc                         | Vaxcyte Inc COM                                                     | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |    166368 | NS      | $7533143.04   | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Verastem Inc                        | VERASTEM INC                                                        | CUSIP: 92337C203<br>LEI: 549300IY0EFBIU8NQC81 | Long             | EC               | CORP              | US        |    102271 | NS      | $966460.95    | 0.12%             |  |  |  | No            |                  1 | On Loan: —       |
| Veracyte Inc                        | Veracyte Inc COM USD0.001                                           | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |    105238 | NS      | $3796987.04   | 0.46%             |  |  |  | No            |                  1 | On Loan: —       |
| Vera Therapeutics Inc.              | VERA THERAPEUTICS INC                                               | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     97421 | NS      | $2772601.66   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Vericel Corporation                 | Vericel Corporation COM NPV                                         | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |     77027 | NS      | $2700566.62   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Incorporated | Vertex Pharmaceuticals Incorporated COM USD0.01                     | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |     23066 | NS      | $9816197.62   | 1.20%             |  |  |  | No            |                  1 | On Loan: No      |
| VERVE THERAPEUTICS INC (CVR)        | VERVE THERAPEUTICS INC (CVR)                                        | CUSIP: 925CVR011<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     82531 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Viking Therapeutics Inc.            | VIKING THERAPEUTICS INC                                             | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    222007 | NS      | $8454026.56   | 1.03%             |  |  |  | No            |                  1 | On Loan: —       |
| VIR Biotechnology Inc               | VIR Biotechnology Inc COM                                           | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    127808 | NS      | $761735.68    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Viridian Therapeutics Inc           | Viridian Therapeutics Inc COM                                       | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |     75786 | NS      | $1790823.18   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor Inc                          | Xencor Inc COM USD0.01                                              | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |     77802 | NS      | $1144467.42   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes PLC                        | Alkermes PLC COM USD0.01                                            | CUSIP: G01767105<br>LEI: N/A                  | Long             | EC               | CORP              | IE        |    200310 | NS      | $6149517.00   | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                        | Biohaven Ltd COM NPV                                                | CUSIP: G1110E107<br>LEI: N/A                  | Long             | EC               | CORP              | VG        |    182127 | NS      | $3132584.40   | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                | ROIVANT SCIENCES LTD                                                | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | BM        |    521586 | NS      | $10426504.14  | 1.28%             |  |  |  | No            |                  1 | On Loan: No      |
| CRISPR Therapeutics AG              | CRISPR Therapeutics AG COM CHF0.03                                  | CUSIP: H17182108<br>LEI: 506700O6IRRIQLT3W370 | Long             | EC               | CORP              | CH        |    171796 | NS      | $10993226.04  | 1.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Uniqure N.V.                        | UNIQURE NV                                                          | CUSIP: N90064101<br>LEI: 724500RPCTZLFYJZ3S98 | Long             | EC               | CORP              | NL        |     92258 | NS      | $6244944.02   | 0.76%             |  |  |  | No            |                  1 | On Loan: No      |
| DREYFUS GOVERNMENT CASH MANAGE      | DREYFUS GOV'T CASH MGMT -INSTITUTIONAL CUSIP 262006208 DGCXX (#289) | CUSIP: N/A<br>LEI: N/A                        | Long             | STIV             | RF                | US        |  73945693 | PA      | $73945692.93  | 9.05%             |  |  |  | No            |                  1 | On Loan: No      |
| GOLDMAN FINANCIAL                   | GOLDMAN FINL SQ TRSRY INST 506                                      | CUSIP: N/A<br>LEI: 549300DAH6N80PM31E83       | Long             | STIV             | RF                | US        |  97147721 | PA      | $97147720.73  | 11.89%            |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $193976352.16 | 23.74%            |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $3043010.85   | 0.37%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $17102586.03  | 2.09%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $23176196.90  | 2.84%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $70057922.68  | 8.57%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $60623279.48  | 7.42%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | S&P BIOTECHNOLOGY SELECT INDUSTRY INDEX SWAP                        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         1 | NC      | $70213015.93  | 8.59%             |  |  |  | No            |                  2 | On Loan: No      |
| DREYFUS                             | DREYFUS TRSRY SECURITIES CASH MGMT                                  | CUSIP: S99991620<br>LEI: N/A                  | Long             | STIV             | RF                | US        |   7220000 | PA      | $7220000.00   | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| GOLDMAN SACHS LIQ ES FD A           | GOLDMAN SACHS FIN GOV 465 INSTITUT                                  | CUSIP: N/A<br>LEI: N/A                        | Long             | STIV             | RF                | US        |  91541150 | PA      | $91541150.00  | 11.20%            |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-12-07

**Name of Applicant:** Direxion Shares ETF Trust

**Signature:** Patrick Rudnick

**Name of Signer:** Patrick Rudnick

**Title:** Principal Executive Officer