# EDGAR Filing Document

**Accession Number:** 0001846368
**File Stem:** 0001172661-25-002950
**Filing Date:** 2025-8
**Character Count:** 12775
**Document Hash:** ac47b9f9c6c38e7836ce3df0211a68c8
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001172661-25-002950.hdr.sgml**: 20250807

**ACCESSION NUMBER**: 0001172661-25-002950

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250807

**DATE AS OF CHANGE**: 20250807

**EFFECTIVENESS DATE**: 20250807

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Simplify Asset Management Inc.
- **CENTRAL INDEX KEY:** 0001846368

**ORGANIZATION NAME:**
- **EIN:** 844936047
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-20937
- **FILM NUMBER:** 251193425

**BUSINESS ADDRESS:**
- **STREET 1:** 10845 GRIFFITH PEAK DRIVE, 2/F
- **CITY:** LAS VEGAS
- **STATE:** NV
- **ZIP:** 89135
- **BUSINESS PHONE:** 646-741-2438

**MAIL ADDRESS:**
- **STREET 1:** 10845 GRIFFITH PEAK DRIVE, 2/F
- **CITY:** LAS VEGAS
- **STATE:** NV
- **ZIP:** 89135

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 06-30-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** Simplify Asset Management Inc.<br>**Address:** 10845 Griffith Peak Drive 2/F<br>Las Vegas, NV 89135

**Form 13F File Number:** 028-20937

**CRD Number (if applicable):** 000309535

**SEC File Number (if applicable):** 801-119255

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Albert Moore<br>**Title:** CCO<br>**Phone:** 617-224-0723

**Signature, Place, and Date of Signing:**

/s/ Albert Moore  New York, NY  08-07-2025<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 89

**Form 13F Information Table Value Total:** $1987745561

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 3M CO | COM | 88579Y101 |  | 244497 | 1606 | SH |  | SOLE |  | 1606 | 0 | 0 |
| ABBOTT LABS | COM | 002824100 |  | 1332082 | 9794 | SH |  | SOLE |  | 9794 | 0 | 0 |
| ABBVIE INC | COM | 00287Y109 |  | 3412438 | 18384 | SH |  | SOLE |  | 18384 | 0 | 0 |
| ABEONA THERAPEUTICS INC | COM NEW | 00289Y206 |  | 3172757 | 558584 | SH |  | SOLE |  | 558584 | 0 | 0 |
| ACHIEVE LIFE SCIENCES INC | COM | 004468500 |  | 2676997 | 1184512 | SH |  | SOLE |  | 1184512 | 0 | 0 |
| ADMA BIOLOGICS INC | COM | 000899104 |  | 6940541 | 381139 | SH |  | SOLE |  | 381139 | 0 | 0 |
| AGILON HEALTH INC | COM | 00857U107 |  | 230350 | 100152 | SH |  | SOLE |  | 100152 | 0 | 0 |
| AGNC INVT CORP | COM | 00123Q104 |  | 790340 | 86000 | SH |  | SOLE |  | 86000 | 0 | 0 |
| AKERO THERAPEUTICS INC | COM | 00973Y108 |  | 7769696 | 145609 | SH |  | SOLE |  | 145609 | 0 | 0 |
| ALIGNMENT HEALTHCARE INC | COM | 01625V104 |  | 1684494 | 120321 | SH |  | SOLE |  | 120321 | 0 | 0 |
| ANNALY CAPITAL MANAGEMENT IN | COM NEW | 035710839 |  | 1183778 | 62900 | SH |  | SOLE |  | 62900 | 0 | 0 |
| APPLIED THERAPEUTICS INC | COM | 03828A101 |  | 1396063 | 4487505 | SH |  | SOLE |  | 4487505 | 0 | 0 |
| ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 |  | 5740237 | 409432 | SH |  | SOLE |  | 409432 | 0 | 0 |
| ARGENX SE | SPONSORED ADR | 04016X101 |  | 808640 | 1467 | SH |  | SOLE |  | 1467 | 0 | 0 |
| ASTRAZENECA PLC | SPONSORED ADR | 046353108 |  | 2267676 | 32451 | SH |  | SOLE |  | 32451 | 0 | 0 |
| ATHIRA PHARMA INC | COM | 04746L104 |  | 450823 | 1492792 | SH |  | SOLE |  | 1492792 | 0 | 0 |
| BENITEC BIOPHARMA INC | COM NEW | 08205P209 |  | 809324 | 69173 | SH |  | SOLE |  | 69173 | 0 | 0 |
| BIOHAVEN LTD | COM | G1110E107 |  | 1360049 | 96389 | SH |  | SOLE |  | 96389 | 0 | 0 |
| BOSTON SCIENTIFIC CORP | COM | 101137107 |  | 762933 | 7103 | SH |  | SOLE |  | 7103 | 0 | 0 |
| CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 |  | 397200 | 40000 | SH |  | SOLE |  | 40000 | 0 | 0 |
| CARDINAL HEALTH INC | COM | 14149Y108 |  | 3890609 | 23229 | SH |  | SOLE |  | 23229 | 0 | 0 |
| CENCORA INC | COM | 03073E105 |  | 2624587 | 8753 | SH |  | SOLE |  | 8753 | 0 | 0 |
| CHEWY INC | CL A | 16679L109 |  | 274942 | 6451 | SH |  | SOLE |  | 6451 | 0 | 0 |
| CHIMERA INVT CORP | COM SHS | 16934Q802 |  | 707717 | 51025 | SH |  | SOLE |  | 51025 | 0 | 0 |
| COOPER COS INC | COM | 216648501 |  | 442900 | 6224 | SH |  | SOLE |  | 6224 | 0 | 0 |
| CVS HEALTH CORP | COM | 126650100 |  | 3239715 | 46966 | SH |  | SOLE |  | 46966 | 0 | 0 |
| DANAHER CORPORATION | COM | 235851102 |  | 3604117 | 18245 | SH |  | SOLE |  | 18245 | 0 | 0 |
| DELCATH SYS INC | COM NEW | 24661P807 |  | 1450154 | 106629 | SH |  | SOLE |  | 106629 | 0 | 0 |
| DEXCOM INC | COM | 252131107 |  | 1802538 | 20650 | SH |  | SOLE |  | 20650 | 0 | 0 |
| EDWARDS LIFESCIENCES CORP | COM | 28176E108 |  | 690594 | 8830 | SH |  | SOLE |  | 8830 | 0 | 0 |
| ELI LILLY  CO | COM | 532457108 |  | 11004625 | 14117 | SH |  | SOLE |  | 14117 | 0 | 0 |
| EYEPOINT PHARMACEUTICALS INC | COM NEW | 30233G209 |  | 747832 | 79472 | SH |  | SOLE |  | 79472 | 0 | 0 |
| FLUOR CORP NEW | COM | 343412102 |  | 3495281 | 68174 | SH |  | SOLE |  | 68174 | 0 | 0 |
| FULCRUM THERAPEUTICS INC | COM | 359616109 |  | 503300 | 73154 | SH |  | SOLE |  | 73154 | 0 | 0 |
| GE HEALTHCARE TECHNOLOGIES I | COMMON STOCK | 36266G107 |  | 1835158 | 24776 | SH |  | SOLE |  | 24776 | 0 | 0 |
| GENEDX HOLDINGS CORP | COM CL A | 81663L200 |  | 5233977 | 56700 | SH |  | SOLE |  | 56700 | 0 | 0 |
| GILEAD SCIENCES INC | COM | 375558103 |  | 5863914 | 52890 | SH |  | SOLE |  | 52890 | 0 | 0 |
| GUARDANT HEALTH INC | COM | 40131M109 |  | 1385877 | 26631 | SH |  | SOLE |  | 26631 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 1563543 | 15536 | SH |  | SOLE |  | 15536 | 0 | 0 |
| INSULET CORP | COM | 45784P101 |  | 316065 | 1006 | SH |  | SOLE |  | 1006 | 0 | 0 |
| INTUITIVE SURGICAL INC | COM NEW | 46120E602 |  | 4727124 | 8699 | SH |  | SOLE |  | 8699 | 0 | 0 |
| IQVIA HLDGS INC | COM | 46266C105 |  | 1251265 | 7940 | SH |  | SOLE |  | 7940 | 0 | 0 |
| ISHARES BITCOIN TRUST ETF | SHS BEN INT | 46438F101 |  | 30518400 | 510000 | SH | Call | SOLE |  | 510000 | 0 | 0 |
| ISHARES TR | CORE US AGGBD ET | 464287226 |  | 308446528 | 3109340 | SH |  | SOLE |  | 3109340 | 0 | 0 |
| ISHARES TR | CORE S ETF | 464287200 |  | 691301367 | 1113386 | SH |  | SOLE |  | 1113386 | 0 | 0 |
| JOHNSON  JOHNSON | COM | 478160104 |  | 1528264 | 10005 | SH |  | SOLE |  | 10005 | 0 | 0 |
| LEAP THERAPEUTICS INC | COM NEW | 52187K200 |  | 254550 | 857360 | SH |  | SOLE |  | 857360 | 0 | 0 |
| LIGAND PHARMACEUTICALS INC | COM NEW | 53220K504 |  | 678670 | 5970 | SH |  | SOLE |  | 5970 | 0 | 0 |
| LIVANOVA PLC | SHS | G5509L101 |  | 400903 | 8905 | SH |  | SOLE |  | 8905 | 0 | 0 |
| MILESTONE PHARMACEUTICALS IN | COM | 59935V107 |  | 1920600 | 990000 | SH |  | SOLE |  | 990000 | 0 | 0 |
| NATIONAL VISION HLDGS INC | COM | 63845R107 |  | 6470665 | 281211 | SH |  | SOLE |  | 281211 | 0 | 0 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 |  | 1343628 | 51998 | SH |  | SOLE |  | 51998 | 0 | 0 |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 |  | 5844208 | 46497 | SH |  | SOLE |  | 46497 | 0 | 0 |
| PACIRA BIOSCIENCES INC | COM | 695127100 |  | 2888148 | 120843 | SH |  | SOLE |  | 120843 | 0 | 0 |
| PHATHOM PHARMACEUTICALS INC | COM | 71722W107 |  | 5005357 | 521935 | SH |  | SOLE |  | 521935 | 0 | 0 |
| PHILIP MORRIS INTL INC | COM | 718172109 |  | 5108929 | 28051 | SH |  | SOLE |  | 28051 | 0 | 0 |
| PLAINS GP HLDGS L P | LTD PARTNR INT A | 72651A207 |  | 24721955 | 1272360 | SH |  | SOLE |  | 1272360 | 0 | 0 |
| PURECYCLE TECHNOLOGIES INC | COM | 74623V103 |  | 7110533 | 519017 | SH |  | SOLE |  | 519017 | 0 | 0 |
| QUEST DIAGNOSTICS INC | COM | 74834L100 |  | 1465960 | 8161 | SH |  | SOLE |  | 8161 | 0 | 0 |
| QVC GROUP INC | COM SER A NEW | 74915M605 |  | 33000 | 12000 | SH |  | SOLE |  | 12000 | 0 | 0 |
| REGENERON PHARMACEUTICALS | COM | 75886F107 |  | 1940925 | 3697 | SH |  | SOLE |  | 3697 | 0 | 0 |
| RESMED INC | COM | 761152107 |  | 2581290 | 10005 | SH |  | SOLE |  | 10005 | 0 | 0 |
| REVVITY INC | COM | 714046109 |  | 1395283 | 14426 | SH |  | SOLE |  | 14426 | 0 | 0 |
| RITHM CAPITAL CORP | COM NEW | 64828T201 |  | 1604140 | 142085 | SH |  | SOLE |  | 142085 | 0 | 0 |
| SANOFI | SPONSORED ADR | 80105N105 |  | 1000790 | 20716 | SH |  | SOLE |  | 20716 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | US EQT PLS UPSID | 82889N301 |  | 85560543 | 1913678 | SH |  | SOLE |  | 1913678 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | TARGET 15 DISTRI | 82889N350 |  | 26630000 | 1000000 | SH |  | SOLE |  | 1000000 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | PIPER SANDLER US | 82889N327 |  | 2530809 | 91464 | SH |  | SOLE |  | 91464 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | NEXT INTANGIBLE | 82889N475 |  | 686375 | 22303 | SH |  | SOLE |  | 22303 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | NATL MUNI BD ETF | 82889N442 |  | 67824759 | 2714076 | SH |  | SOLE |  | 2714076 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | MULTI QIS ALTERN | 82889N533 |  | 86368364 | 3927620 | SH |  | SOLE |  | 3927620 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | INTMD TERM TRSRY | 82889N798 |  | 40769235 | 3022182 | SH |  | SOLE |  | 3022182 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | CURRENCY STRATEG | 82889N368 |  | 7566932 | 289943 | SH |  | SOLE |  | 289943 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | BARRIER INCOME | 82889N335 |  | 28842000 | 1100000 | SH |  | SOLE |  | 1100000 | 0 | 0 |
| SIMPLIFY EXCHANGE TRADED FUN | AGGREGATE BOND E | 82889N723 |  | 107188763 | 5193254 | SH |  | SOLE |  | 5193254 | 0 | 0 |
| SPDR GOLD TR | GOLD SHS | 78463V107 |  | 306781125 | 997500 | SH | Put | SOLE |  | 997500 | 0 | 0 |
| STRYKER CORPORATION | COM | 863667101 |  | 434402 | 1098 | SH |  | SOLE |  | 1098 | 0 | 0 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 |  | 234584 | 25049 | SH |  | SOLE |  | 25049 | 0 | 0 |
| TESLA INC | COM | 88160R101 |  | 7668630 | 24141 | SH |  | SOLE |  | 24141 | 0 | 0 |
| TG THERAPEUTICS INC | COM | 88322Q108 |  | 367242 | 10204 | SH |  | SOLE |  | 10204 | 0 | 0 |
| THE CIGNA GROUP | COM | 125523100 |  | 510416 | 1544 | SH |  | SOLE |  | 1544 | 0 | 0 |
| THERMO FISHER SCIENTIFIC INC | COM | 883556102 |  | 870523 | 2147 | SH |  | SOLE |  | 2147 | 0 | 0 |
| TSCAN THERAPEUTICS INC | COM | 89854M101 |  | 1518028 | 1046916 | SH |  | SOLE |  | 1046916 | 0 | 0 |
| TWO HBRS INVT CORP | COM | 90187B804 |  | 573502 | 53250 | SH |  | SOLE |  | 53250 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 553036 | 15210 | SH |  | SOLE |  | 15210 | 0 | 0 |
| UNITEDHEALTH GROUP INC | COM | 91324P102 |  | 1263790 | 4051 | SH |  | SOLE |  | 4051 | 0 | 0 |
| VANECK BITCOIN ETF | SH BEN INT | 92189K105 |  | 7575330 | 248616 | SH |  | SOLE |  | 248616 | 0 | 0 |
| VERTEX PHARMACEUTICALS INC | COM | 92532F100 |  | 481261 | 1081 | SH |  | SOLE |  | 1081 | 0 | 0 |
| ZEVRA THERAPEUTICS INC | COM NEW | 488445206 |  | 1295070 | 147000 | SH |  | SOLE |  | 147000 | 0 | 0 |

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