# EDGAR Filing Document

**Accession Number:** 0001293971
**File Stem:** 0001193125-25-132945
**Filing Date:** 2025-6
**Character Count:** 13167
**Document Hash:** 6a7490108bf66949768f408f90c7f60b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-132945.hdr.sgml**: 20250602

**ACCESSION NUMBER**: 0001193125-25-132945

**CONFORMED SUBMISSION TYPE**: S-8 POS

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250602

**DATE AS OF CHANGE**: 20250602

**EFFECTIVENESS DATE**: 20250602

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** bluebird bio, Inc.
- **CENTRAL INDEX KEY:** 0001293971
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8 POS
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-194340
- **FILM NUMBER:** 251013447

**BUSINESS ADDRESS:**
- **STREET 1:** 455 GRAND UNION BOULEVARD
- **CITY:** SOMERVILLE
- **STATE:** MA
- **ZIP:** 02145
- **BUSINESS PHONE:** 339-499-9300

**MAIL ADDRESS:**
- **STREET 1:** 455 GRAND UNION BOULEVARD
- **CITY:** SOMERVILLE
- **STATE:** MA
- **ZIP:** 02145

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Genetix Pharmaceuticals Inc
- **DATE OF NAME CHANGE:** 20040616

**As filed with the Securities and Exchange Commission on June 2, 2025** 

**Registration No. 333-189560** 

**Registration No. 333-283235** 

**Registration No. 333-272714** 

**Registration No. 333-194340** 

**Registration No. 333-202283** 

**Registration No. 333-209715** 

**Registration No. 333-216179** 

**Registration No. 333-223132** 

**Registration No. 333-229768** 

**Registration No. 333-236490** 

**Registration No. 333-253398** 

**Registration No. 333-270922** 

**Registration No. 333-257135** 

**Registration No. 333-263310** 

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**WASHINGTON, D.C. 20549** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-189560** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-283235** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-272714** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-194340** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-202283** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-209715** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-216179** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-223132** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-229768** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-236490** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-253398** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-270922** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-257135** 

**Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-263310** 

***UNDER***

***THE SECURITIES ACT OF 1933***

## bluebird bio, Inc.
**(Exact name of registrant as specified in its charter)** 

---

| | |
|:---|:---|
| **Delaware** | **13-3680878** |
| **(State or other jurisdiction of**<br> **incorporation or organization)** | **(I.R.S. Employer**<br> **Identification No.)** |

---

**455 Grand Union Boulevard** 

**Somerville, MA 02145** 

**(339) 499-9300** 

**(Address of Principal Executive Offices) (Zip Code)** 

**SECOND AMENDED AND RESTATED 2002 EMPLOYEE, DIRECTOR AND CONSULTANT PLAN** 

**2010 STOCK OPTION AND GRANT PLAN** 

**2013 EMPLOYEE STOCK PURCHASE PLAN** 

**2013 STOCK OPTION AND INCENTIVE PLAN** 

**2021 INDUCEMENT PLAN** 

**AMENDED AND RESTATED 2023 INCENTIVE AWARD PLAN** 

**2023 INCENTIVE AWARD PLAN** 

**(Full titles of the plans)** 

**David Meek** 

**President** 

**bluebird bio, Inc.** 

**455 Grand Union Boulevard** 

**Somerville, MA 02145** 

**(339) 499-9300** 

**(Name, address, including zip code, and telephone number, including area code, of agent for service)** 

***Copies to:***

---

| | | |
|:---|:---|:---|
| **Mark A. Stagliano, Esq.**<br> **Wachtell, Lipton, Rosen & Katz**<br> **51 West 52nd Street**<br> **New York, New York 10019**<br> **(212) 403-1000** | **Gregg Griner, Esq.**<br> **Albert Vanderlaan, Esq.**<br> **Orrick, Herrington & Sutcliffe LLP**<br> **222 Berkeley St., Suite 2000**<br> **Boston, MA 02116**<br> **(617) 880-2212** | **Matthew S. Arenson, P.C.**<br> **Kirkland & Ellis LLP**<br> **98 SE 7th St, Suite 700**<br> **Miami, FL 33131**<br> **(305) 432-5600** |

---

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

---

| | | | |
|:---|:---|:---|:---|
| Large accelerated filer | ☐ | Accelerated filer | ☐ |
| Non-accelerated filer | ☒ | Smaller reporting company | ☒ |
|  |  | Emerging growth company | ☐ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

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**DEREGISTRATION OF SECURITIES** 

These post-effective amendments (the "***Post-Effective Amendments***"), filed by bluebird bio, Inc., a Delaware corporation (the "***Company***"), remove from registration all shares of common stock, par value $0.01 per share, of the Company (the "***Common Stock***") previously registered under the following Registration Statements on Form S-8 filed by the Company (the "***Registration Statements***") with the U.S. Securities and Exchange Commission (the "***SEC***") pertaining to the registration of shares of Common Stock.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-189560, which was previously filed with the SEC
on [June 24, 2013](http://www.sec.gov/Archives/edgar/data/1293971/000119312513269157/d557474ds8.htm) , registering 280,220 shares of Common Stock under the Second Amended and Restated 2002 Employee, Director and Consultant Plan,
3,620,296 shares of Common Stock under the 2010 Stock Option and Grant Plan, 955,000 shares of Common Stock under the 2013 Stock Option and Incentive Plan and 238,000 shares of Common Stock under the 2013 Employee Stock Purchase Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-283235, which was previously filed with the SEC
on [November 14, 2024](http://www.sec.gov/Archives/edgar/data/1293971/000129397124000082/blues-820241114.htm) , registering 15,000,000 shares of Common Stock under the Amended and Restated 2023 Incentive Award Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-272714, which was previously filed with the SEC
on [June 16, 2023](http://www.sec.gov/Archives/edgar/data/1293971/000129397123000027/blues-820230616.htm) , registering 5,200,000 shares of Common Stock under the 2023 Incentive Award Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-194340, which was previously filed with the SEC
on [March 5, 2014](http://www.sec.gov/Archives/edgar/data/1293971/000119312514084758/d686500ds8.htm) , registering 960,320 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-202283, which was previously filed with the SEC
on [February 25, 2015](http://www.sec.gov/Archives/edgar/data/1293971/000095012315003637/blue-s8_20150225.htm) , registering 1,293,592 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-209715, which was previously filed with the SEC
on [February 25, 2016](http://www.sec.gov/Archives/edgar/data/1293971/000156459016013396/blue-s8_20160225.htm) , registering 1,475,755 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-216179, which was previously filed with the SEC
on [February 22, 2017](http://www.sec.gov/Archives/edgar/data/1293971/000156459017002028/blue-s8.htm) , registering 1,627,676 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-223132, which was previously filed with the SEC
on [February 21, 2018](http://www.sec.gov/Archives/edgar/data/1293971/000156459018002715/blue-s8.htm) , registering 1,976,240 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-229768, which was previously filed with the SEC
on [February 21, 2019](http://www.sec.gov/Archives/edgar/data/1293971/000119312519047054/d674761ds8.htm) , registering 2,189,530 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-236490, which was previously filed with the SEC
on [February 18, 2020](http://www.sec.gov/Archives/edgar/data/1293971/000119312520040467/d851315ds8.htm) , registering 2,214,719 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-253398, which was previously filed with the SEC
on [February 23, 2021](http://www.sec.gov/Archives/edgar/data/1293971/000129397121000015/blues-820210223.htm) , registering 2,657,263 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-270922, which was previously filed with the SEC
on [March 29, 2023](http://www.sec.gov/Archives/edgar/data/1293971/000119312523082900/d425204ds8.htm) , registering 3,316,932 shares of Common Stock under the 2013 Stock Option and Incentive Plan;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-257135, which was previously filed with the SEC
on [June 15, 2021](http://www.sec.gov/Archives/edgar/data/1293971/000129397121000051/blues-820210615.htm) , registering 1,400,000 shares of Common Stock under the 2013 Employee Stock Purchase Plan and 600,000 shares of Common Stock
under the 2021 Inducement Plan; and

------

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration No. 333-263310, which was previously filed with the SEC
on [March 4, 2022](http://www.sec.gov/Archives/edgar/data/1293971/000129397122000017/blues-820220304.htm) , registering 2,844,617 shares of Common Stock under the 2013 Stock Option and Incentive Plan and 650,000 shares of Common Stock
under the 2021 Inducement Plan.

On February 21, 2025, the Company entered into an Agreement and Plan of Merger (as amended from time to time, the "***Merger Agreement***") with Beacon Parent Holdings, L.P., a Delaware limited partnership ("***Parent***") and Beacon Merger Sub, Inc., a Delaware corporation and an indirect wholly owned subsidiary of Parent ("***Merger Sub***"). On June 2, 2025, pursuant to the Merger Agreement, Merger Sub merged with and into the Company, with the Company surviving as an indirect wholly owned subsidiary of Parent (the "***Merger***").

As a result of the Merger, the Company has terminated all offerings of the Company's securities registered pursuant to its existing registration statements under the Securities Act of 1933, as amended, including the Registration Statements. The Company, by filing these Post-Effective Amendments, hereby terminates the effectiveness of the Registration Statements and removes from registration any and all plan interests and any and all securities registered for issuance under the Registration Statements that remain unsold as of the date hereof. This filing is made in accordance with an undertaking made by the Company in each of the Registration Statements to remove from registration by means of a post-effective amendment any securities that had been registered for issuance that remain unsold at the termination of the offering.

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SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused these Post-Effective Amendments to the Registration Statements on Form S-8 to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Somerville, State of Massachusetts on June 2, 2025.

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| | |
|:---|:---|
| **BLUEBIRD BIO, INC.** | **BLUEBIRD BIO, INC.** |
| By: | /s/ David Meek |
|  | Name: David Meek |
|  | Title: President |

---

No other person is required to sign these Post-Effective Amendments in reliance upon Rule 478 under the Securities Act of 1933, as amended.