# EDGAR Filing Document

**Accession Number:** 0001130166
**File Stem:** 0001641172-25-021746
**Filing Date:** 2025-7
**Character Count:** 2544
**Document Hash:** 8589d6b83b7f113bc74cefce0aaf8e08
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001641172-25-021746.hdr.sgml**: 20250922

**ACCESSION NUMBER**: 0001641172-25-021746

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250731

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Cyclacel Pharmaceuticals, Inc.
- **CENTRAL INDEX KEY:** 0001130166
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 911766850
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 200 CONNELL DRIVE
- **STREET 2:** SUITE 1500
- **CITY:** BERKELEY HEIGHTS
- **STATE:** NJ
- **ZIP:** 07922
- **BUSINESS PHONE:** 908-517-7330

**MAIL ADDRESS:**
- **STREET 1:** 200 CONNELL DRIVE
- **STREET 2:** SUITE 1500
- **CITY:** BERKELEY HEIGHTS
- **STATE:** NJ
- **ZIP:** 07922

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Cyclacel Pharmaceuticals, Inc.
- **DATE OF NAME CHANGE:** 20060329

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** XCYTE THERAPIES INC
- **DATE OF NAME CHANGE:** 20001218

**CYCLACEL PHARMACEUTICALS, INC.**

**Level 10, Tower 11, .Avenue 5, The Horizon**

**Bangsar South City, No. 8, Jalan Kerinchi, 59200, Kuala Lumpur, Malaysia**

July 31, 2025

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549

*via EDGAR*

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| | |
|:---|:---|
| **RE:** | Cyclacel Pharmaceuticals, Inc. (CIK0001130166) |
|  | Registration Statement on Form S-1 |
|  | Filed: July 30, 2025 |
|  | Securities Act File No.: 333-288911 |

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**Request for Acceleration of Effectiveness**

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Cyclacel Pharmaceuticals, Inc. (the "Registrant") hereby respectfully requests acceleration of its Registration Statement on Form S-1 (File No. 333-288911), filed on July 30, 2025, so that it will become effective at 5:00 p.m. (Eastern time) on August 4, 2025, or as soon as practicable thereafter.

If you have any questions, or require any additional information, please do not hesitate to email Debbie Klis, the Registrant's outside counsel at Rimon P.C. via email at <u>debbie.klis@rimonlaw.com</u> or by phone on 202-935-3390.

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| | |
|:---|:---|
| Very truly yours, | Very truly yours, |
| Cyclacel Pharmaceuticals, Inc. | Cyclacel Pharmaceuticals, Inc. |
| By: | */s/ Datuk Dr. Doris Wong* |
|  | Datuk Dr. Doris Wong |
|  | Chief Executive Officer |

---