# EDGAR Filing Document

**Accession Number:** 0001465837
**File Stem:** 0000895345-23-000135
**Filing Date:** 2023-2
**Character Count:** 10923
**Document Hash:** 5d9a4a5b29b6924249ad7625a25ad336
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000895345-23-000135.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0000895345-23-000135

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230214

**DATE AS OF CHANGE**: 20230214

**EFFECTIVENESS DATE**: 20230214

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Boxer Capital, LLC
- **CENTRAL INDEX KEY:** 0001465837
- **IRS NUMBER:** 203828456
- **STATE OF INCORPORATION:** DE

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-17339
- **FILM NUMBER:** 23626077

**BUSINESS ADDRESS:**
- **STREET 1:** 12860 EL CAMINO REAL
- **STREET 2:** SUITE 300
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92130
- **BUSINESS PHONE:** (858) 400-3112

**MAIL ADDRESS:**
- **STREET 1:** 12860 EL CAMINO REAL
- **STREET 2:** SUITE 300
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92130

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2022

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** Boxer Capital LLC<br>**Address:** 12860 El Camino Real<br>Suite 300<br>San Diego, CA 92130

**Form 13F File Number:** 028-17339

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Aaron I. Davis<br>**Title:** Chief Executive Officer<br>**Phone:** 858-400-3114

**Signature, Place, and Date of Signing:**

/s/ Aaron I. Davis  San Diego, CA  02-14-2023<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 71

**Form 13F Information Table Value Total:** $1896920313

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 2Seventy Bio Inc | COMMON STOCK | 901384107 |  | 4308663 | 459836 | SH |  | OTR |  | 459836 | 0 | 0 |
| 89Bio Inc | COM | 282559103 |  | 17822000 | 1400000 | SH |  | OTR |  | 1400000 | 0 | 0 |
| Akero Therapeutics Inc | COM | 00973Y108 |  | 45565926 | 831495 | SH |  | OTR |  | 831495 | 0 | 0 |
| Alaunos Therapeutics Inc | COM | 98973P101 |  | 973650 | 1500000 | SH |  | OTR |  | 1500000 | 0 | 0 |
| Amicus Therapeutics Inc | COM | 03152W109 |  | 28388250 | 2325000 | SH |  | OTR |  | 2325000 | 0 | 0 |
| Amylyx Pharmaceuticals Inc | COM | 03237H101 |  | 77003800 | 2084000 | SH |  | OTR |  | 2084000 | 0 | 0 |
| AnaptysBio Inc | COM | 032724106 |  | 40287000 | 1300000 | SH |  | OTR |  | 1300000 | 0 | 0 |
| Apellis Pharmaceuticals Inc | COM | 03753U106 |  | 81494960 | 1576000 | SH |  | OTR |  | 1576000 | 0 | 0 |
| Arcus Biosciences Inc | COM | 03969F109 |  | 29617896 | 1432200 | SH |  | OTR |  | 1432200 | 0 | 0 |
| Arvinas Inc | COM | 04335A105 |  | 5131500 | 150000 | SH |  | OTR |  | 150000 | 0 | 0 |
| Ascendis Pharma A/S | SPONSORED ADR | 04351P101 |  | 11602350 | 95000 | SH |  | OTR |  | 95000 | 0 | 0 |
| Atreca Inc | CL A COM | 04965G109 |  | 1763188 | 2202333 | SH |  | OTR |  | 2202333 | 0 | 0 |
| Avidity Biosciences Inc | COM | 05370A108 |  | 24882246 | 1121327 | SH |  | OTR |  | 1121327 | 0 | 0 |
| Axsome Therapeutics Inc | COM | 05464T104 |  | 30852000 | 400000 | SH |  | OTR |  | 400000 | 0 | 0 |
| BeiGene Ltd | SPONSORED ADR | 07725L102 |  | 109970000 | 500000 | SH |  | OTR |  | 500000 | 0 | 0 |
| Bellicum Pharmaceuticals Inc | COM NEW | 079481404 |  | 41004 | 56950 | SH |  | OTR |  | 56950 | 0 | 0 |
| Bellus Health Inc New | COM NEW | 07987C204 |  | 26304000 | 3200000 | SH |  | OTR |  | 3200000 | 0 | 0 |
| BioAtla Inc | COM | 09077B104 |  | 5662363 | 686347 | SH |  | OTR |  | 686347 | 0 | 0 |
| Black Diamond Therapeutics I | COM | 09203E105 |  | 3626744 | 2014858 | SH |  | OTR |  | 2014858 | 0 | 0 |
| Cabaletta Bio Inc | COM | 12674W109 |  | 4995000 | 540000 | SH |  | OTR |  | 540000 | 0 | 0 |
| Centessa Pharmaceuticals PLC | SPONSORED ADS | 152309100 |  | 38785245 | 1251137 | SH |  | OTR |  | 1251137 | 0 | 0 |
| Cogent Biosciences Inc | COM | 19240Q201 |  | 6069000 | 525000 | SH |  | OTR |  | 525000 | 0 | 0 |
| Cullinan Oncology Inc | COM | 230031106 |  | 11331565 | 1074082 | SH |  | OTR |  | 1074082 | 0 | 0 |
| Cytokinetics Inc | COM NEW | 23282W605 |  | 96222000 | 2100000 | SH |  | OTR |  | 2100000 | 0 | 0 |
| Day One Biopharmaceuticals I | COM | 23954D109 |  | 25607573 | 1189943 | SH |  | OTR |  | 1189943 | 0 | 0 |
| DBV Technologies S A | SPONSORED ADR | 23306J101 |  | 2218500 | 1450000 | SH |  | OTR |  | 1450000 | 0 | 0 |
| Disc Medicine Inc | COM | 254604101 |  | 175500 | 130000 | SH |  | OTR |  | 130000 | 0 | 0 |
| EQRx Inc | COM | 26886C107 |  | 2460000 | 1000000 | SH |  | OTR |  | 1000000 | 0 | 0 |
| Exelixis Inc | COM | 30161Q104 |  | 18446000 | 1150000 | SH |  | OTR |  | 1150000 | 0 | 0 |
| Fate Therapeutics Inc | COM | 31189P102 |  | 12612500 | 1250000 | SH |  | OTR |  | 1250000 | 0 | 0 |
| Geron Corp | COM | 374163103 |  | 19602000 | 8100000 | SH |  | OTR |  | 8100000 | 0 | 0 |
| Gossamer Bio Inc | COM | 38341P102 |  | 7241134 | 3336928 | SH |  | OTR |  | 3336928 | 0 | 0 |
| Health Sciences Acq Corp 2 | ORD SHS | G4411D109 |  | 2495000 | 250000 | SH |  | OTR |  | 250000 | 0 | 0 |
| Ideaya Biosciences Inc | COM | 45166A102 |  | 40025094 | 2202812 | SH |  | OTR |  | 2202812 | 0 | 0 |
| Iovance Biotherapeutics Inc | COM | 462260100 |  | 9617800 | 1505133 | SH |  | OTR |  | 1505133 | 0 | 0 |
| iTeos Therapeutics Inc | COM | 46565G104 |  | 42068752 | 2154058 | SH |  | OTR |  | 2154058 | 0 | 0 |
| Iveric Bio Inc | COM | 46583P102 |  | 17663250 | 825000 | SH |  | OTR |  | 825000 | 0 | 0 |
| Kinnate Biopharma Inc | COM | 49705R105 |  | 3111000 | 510000 | SH |  | OTR |  | 510000 | 0 | 0 |
| MEI Pharma Inc | COM NEW | 55279B202 |  | 709629 | 2913091 | SH |  | OTR |  | 2913091 | 0 | 0 |
| Mereo Biopharma Group PLC | SPON ADS | 589492107 |  | 1687500 | 2250000 | SH |  | OTR |  | 2250000 | 0 | 0 |
| Merus N V | COM | N5749R100 |  | 29393000 | 1900000 | SH |  | OTR |  | 1900000 | 0 | 0 |
| Milestone Pharmaceuticals In | COM | 59935V107 |  | 2767490 | 698861 | SH |  | OTR |  | 698861 | 0 | 0 |
| Mirati Therapeutics Inc | COM | 60468T105 |  | 90620000 | 2000000 | SH |  | OTR |  | 2000000 | 0 | 0 |
| NGM Biopharmaceuticals Inc | COM | 62921N105 |  | 2510000 | 500000 | SH |  | OTR |  | 500000 | 0 | 0 |
| Nurix Therapeutics Inc | COM | 67080M103 |  | 13449314 | 1224892 | SH |  | OTR |  | 1224892 | 0 | 0 |
| Nuvalent Inc | COM | 670703107 |  | 36039518 | 1210192 | SH |  | OTR |  | 1210192 | 0 | 0 |
| Nuvation Bio Inc | *W EXP 07/07/202 | 67080N119 |  | 38533 | 266666 | SH |  | OTR |  | 266666 | 0 | 0 |
| Oric Pharmaceuticals Inc | COM | 68622P109 |  | 7362401 | 1054000 | SH |  | OTR |  | 1054000 | 0 | 0 |
| Panacea Acquisition Corp II | CL A SHS | G6882C106 |  | 6208060 | 500000 | SH |  | OTR |  | 500000 | 0 | 0 |
| PMV Pharmaceuticals Inc | COM | 69353Y103 |  | 27525016 | 3163795 | SH |  | OTR |  | 3163795 | 0 | 0 |
| Point Biopharma Global Inc | COM | 730541109 |  | 18225000 | 2500000 | SH |  | OTR |  | 2500000 | 0 | 0 |
| Prometheus Biosciences Inc | COM | 74349U108 |  | 208725000 | 1897500 | SH |  | OTR |  | 1897500 | 0 | 0 |
| Protara Therapeutics Inc | COM STK | 74365U107 |  | 560728 | 209227 | SH |  | OTR |  | 209227 | 0 | 0 |
| Prothena Corp PLC | SHS | G72800108 |  | 18075000 | 300000 | SH |  | OTR |  | 300000 | 0 | 0 |
| Rain Oncology Inc | COM | 75082Q105 |  | 17177696 | 2147212 | SH |  | OTR |  | 2147212 | 0 | 0 |
| Reata Pharmaceuticals Inc | CL A | 75615P103 |  | 46727852 | 1230004 | SH |  | OTR |  | 1230004 | 0 | 0 |
| Relay Therapeutics Inc | COM | 75943R102 |  | 32406832 | 2169132 | SH |  | OTR |  | 2169132 | 0 | 0 |
| Revolution Medicines Inc | COM | 76155X100 |  | 94905168 | 3984264 | SH |  | OTR |  | 3984264 | 0 | 0 |
| Rocket Pharmaceuticals Inc | COM | 77313F106 |  | 28690618 | 1466051 | SH |  | OTR |  | 1466051 | 0 | 0 |
| Sage Therapeutics Inc | COM | 78667J108 |  | 41725160 | 1094000 | SH |  | OTR |  | 1094000 | 0 | 0 |
| Selecta Biosciences Inc | COM | 816212104 |  | 3711001 | 3284072 | SH |  | OTR |  | 3284072 | 0 | 0 |
| Springworks Therapeutics Inc | COM | 85205L107 |  | 88994281 | 3421541 | SH |  | OTR |  | 3421541 | 0 | 0 |
| Surrozen Inc | *W EXP 08/01/203 | 86889P117 |  | 4393 | 66666 | SH |  | OTR |  | 66666 | 0 | 0 |
| Tango Therapeutics Inc | COM | 87583X109 |  | 51646405 | 7123642 | SH |  | OTR |  | 7123642 | 0 | 0 |
| Theseus Pharmaceuticals Inc | COM | 88369M101 |  | 2066700 | 415000 | SH |  | OTR |  | 415000 | 0 | 0 |
| Third Harmonic Bio Inc | COM | 88427A107 |  | 2452793 | 570417 | SH |  | OTR |  | 570417 | 0 | 0 |
| Tyra Biosciences Inc | COM | 90240B106 |  | 49007528 | 6448359 | SH |  | OTR |  | 6448359 | 0 | 0 |
| Ventyx Biosciences Inc | COM | 92332V107 |  | 27871500 | 850000 | SH |  | OTR |  | 850000 | 0 | 0 |
| Veru Inc | COM | 92536C103 |  | 1833744 | 347300 | SH |  | OTR |  | 347300 | 0 | 0 |
| Viking Therapeutics Inc | COM | 92686J106 |  | 14100000 | 1500000 | SH |  | OTR |  | 1500000 | 0 | 0 |
| Xenon Pharmaceuticals Inc | COM | 98420N105 |  | 23658000 | 600000 | SH |  | OTR |  | 600000 | 0 | 0 |

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