# EDGAR Filing Document

**Accession Number:** 0001421876
**File Stem:** 0001171843-26-003711
**Filing Date:** 2026-5
**Character Count:** 9328
**Document Hash:** 2066dd9e5726bc8a4b9c576aaa17eb88
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001171843-26-003711.hdr.sgml**: 20260527

**ACCESSION NUMBER**: 0001171843-26-003711

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260526

**FILED AS OF DATE**: 20260527

**DATE AS OF CHANGE**: 20260527

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Lakefront Biotherapeutics NV
- **CENTRAL INDEX KEY:** 0001421876
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** C9

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-37384
- **FILM NUMBER:** 261022034

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** SCHALIENHOEVEDREEF 20T
- **CITY:** 2800 MECHELEN
- **PROVINCE COUNTRY:** C9
- **BUSINESS PHONE:** 3215342900

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** SCHALIENHOEVEDREEF 20T
- **CITY:** 2800 MECHELEN
- **PROVINCE COUNTRY:** C9

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** GALAPAGOS NV
- **DATE OF NAME CHANGE:** 20071220

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**Form 6-K**

**REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934**

**For the month of May 2026**

Commission File Number: **001-37384**

**Lakefront Biotherapeutics**

(Translation of registrant's name into English)

**Generaal De Wittelaan L11 A3 2800 Mechelen, Belgium**

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F [ X ] &nbsp;&nbsp;&nbsp;&nbsp; Form 40-F [ ]

The information contained in this Report on Form 6-K, including Exhibit 99.1, is hereby incorporated by reference into the Company's Registration Statements on Form S-8 (File Nos. 333-204567, 333-208697, 333-211834, 333-215783, 333- 218160, 333-225263, 333-231765, 333-249416, 333-260500, 333-268756, 333-275886, 333-283361, and 333-292050).

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On May 26, 2026, the Registrant issued a press release, a copy of which is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

[Exhibit 99.1. Press release dated May 26, 2026](exh_991.htm)

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**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

---

| | |
|:---|:---|
|  | <u>**&nbsp;&nbsp;&nbsp;&nbsp;Lakefront Biotherapeutics&nbsp;&nbsp;&nbsp;&nbsp;**</u> |
|  | (Registrant) |
| Date: May 27, 2026 | <u>&nbsp;&nbsp;&nbsp;&nbsp;/s/ Annelies Denecker&nbsp;&nbsp;&nbsp;&nbsp;</u> |
|  | Annelies Denecker |
|  | Company Secretary |

---

## Exhibit 99.1

**EXHIBIT 99.1**

**Lakefront Receives Transparency Notification from Bank of America**

**Mechelen, Belgium; May 26, 2026, 22.01 CET; regulated information – Lakefront Biotherapeutics NV (Euronext & NASDAQ: LKFT) received a transparency notification from Bank of America.**

Pursuant to Belgian transparency legislation<sup>1</sup>, Lakefront received a transparency notification from Bank of America Corporation on May 20, 2026. The notification indicates that Bank of America Corporation, as controlling entity, crossed above the threshold of 5% of Lakefront' voting rights on May 13, 2026, following the acquisition of Lakefront' voting rights and equivalent financial instruments.

On May 20, 2026, Bank of America Corporation (taking into account the holding of its affiliates) owned 623,434 voting rights and 5,502,802 equivalent financial instruments, representing together 9.30% of Lakefront' currently outstanding 65,897,071 shares.

**Summary of the transactions:**

---

| | | | | |
|:---|:---|:---|:---|:---|
| **Date on which the threshold was crossed** | **Date of notification** | **Direct voting rights after the transaction** | **Equivalent financial instruments after the transaction** | **Total (%)**<br>**voting rights** |
| May 13, 2026 | May 20, 2026 | 0.95% | 8.35% | 9.30% |

---

**Content of the notification from Bank of America Corporation:**

The notification dated May 20, 2026, contains the following information:

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Date of notification: May 20, 2026

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Date on which the threshold is crossed: May 13, 2026

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Threshold of voting rights crossed (in %): 5%

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Notification by: Bank of America Corporation

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Denominator: 65,897,071

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Reason for the notification: Acquisition or disposal of financial instruments that are treated as voting securities

· &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Notified details:

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **A) Voting Rights** | **Previous notification** | **After the transaction** | **After the transaction** | **After the transaction** | **After the transaction** |
| | **# of voting rights** | **# of voting rights** | **# of voting rights** | **% of voting rights** | **% of voting rights** |
| Holder of voting rights |  | Linked to securities | Not linked to securities | Linked to securities | Not linked to securities |
| Bank of America Corporation | 0 | 0 |  | 0.00% |  |
| Bank of America, National Association | 12447 | 14348 |  | 0.02% |  |
| Merrill Lynch International | 225319 | 8234 |  | 0.01% |  |
| Managed Account Advisors LLC | 3 | 0 |  | 0.00% |  |
| BofA Securities, Inc. | 168740 | 600314 |  | 0.91% |  |
| Merrill Lynch, Pierce, Fenner & Smith <br>Incorporated | 14462 | 462 |  | 0.00% |  |
| U.S. Trust Company of Delaware | 121 | 76 |  | 0.00% |  |
| **Subtotal** | 421092 | 623434 |  | 0.95% |  |
|  | **TOTAL** | **623434** | **0** | **0.95%** | **0.00%** |

---

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **B) Equivalent financial instruments** | **After the transaction** | **After the transaction** | **After the transaction** | **After the transaction** | **After the transaction** | **After the transaction** |
| **Holder of equivalent financial instruments** | **Type of financial instrument** | **Expiration date** | **Exercise period or date** | **# of voting rights that may be acquired if the instrument is exercised** | **% of voting rights** | **Settlement** |
| Merrill Lynch International | Right to Recall |  |  | 143430 | 0.22% | physical |
| Merrill Lynch International | Rights of Use |  |  | 6054 | 0.01% | physical |
| BofA Securities, Inc. | Right to Use |  |  | 5068385 | 7.69% | physical |
| Merrill Lynch International | Call Option | 19/06/2026 |  | 100000 | 0.15% | physical |
| Bank of America, National Association | Swaps | 15/10/2027 |  | 48575 | 0.07% | cash |
| Bank of America, National Association | Swaps | 15/06/2027 |  | 14311 | 0.02% | cash |
| Merrill Lynch International | Swaps | 15/01/2027 |  | 10363 | 0.02% | cash |
| Merrill Lynch International | Swaps | 30/04/2027 |  | 44893 | 0.07% | cash |
| Merrill Lynch International | Swaps | 30/06/2027 |  | 819 | 0.00% | cash |
| Merrill Lynch International | Swaps | 15/06/2027 |  | 14311 | 0.02% | cash |
| Merrill Lynch International | Swaps | 10/05/2027 |  | 424 | 0.00% | cash |
| Merrill Lynch International | Swaps | 09/09/2027 |  | 256 | 0.00% | cash |
| Merrill Lynch International | Swaps | 21/06/2027 |  | 273 | 0.00% | cash |
| Merrill Lynch International | Swaps | 15/10/2027 |  | 48575 | 0.07% | cash |
| Merrill Lynch International | Swaps | 30/06/2026 |  | 453 | 0.00% | cash |
| Merrill Lynch International | Swaps | 29/01/2027 |  | 1680 | 0.00% | cash |
|  | **TOTAL** |  |  | **5502802** | **8.35%** |  |

---

---

| | | |
|:---|:---|:---|
| **TOTAL (A&B)** | **# of voting rights** | **% of voting rights** |
|  | **6126236** | **9.30%** |

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The chain of control has been described at the end of the notification (section 11) and can be found <u>here</u>.

**About Lakefront<sup>®</sup>** **Biotherapeutics**

Lakefront Biotherapeutics (formerly known as Galapagos) is a biotechnology company built to bring meaningful medicines to patients with serious diseases in therapeutic areas of unmet need. The Company combines world-class deal making expertise with capital to identify, acquire, and advance promising opportunities that have the potential to drive value for patients and shareholders. Applying a modality-agnostic asset selection approach and operational flexibility, Lakefront Biotherapeutics prioritizes oncology and immunology & inflammation programs with clear clinical proof-of-concept in emerging areas. For more information, visit https://www.lakefrontbio.com or follow us on LinkedIn or X.

**For further information, contact Lakefront Biotherapeutics:**

**Investor Relations** 

Sherri Spear

+1 412 522 6418

sherri.spear@lakefrontbio.com

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<sup>1</sup> Belgian Act of 2 May 2007 on the disclosure of major shareholdings in issuers whose shares are admitted to trading on a regulated market and regarding miscellaneous provisions, as amended from time to time.