# EDGAR Filing Document

**Accession Number:** 0001124524
**File Stem:** 0001104659-26-076480
**Filing Date:** 2026-6
**Character Count:** 22007
**Document Hash:** 252227c9b325c31c3d8e739789fe9b32
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-26-076480.hdr.sgml**: 20260623

**ACCESSION NUMBER**: 0001104659-26-076480

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 13

**FILED AS OF DATE**: 20260622

**DATE AS OF CHANGE**: 20260623

**EFFECTIVENESS DATE**: 20260622

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Cryoport, Inc.
- **CENTRAL INDEX KEY:** 0001124524
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 880313393
- **STATE OF INCORPORATION:** NV
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-296959
- **FILM NUMBER:** 261108954

**BUSINESS ADDRESS:**
- **STREET 1:** 112 WESTWOOD PLACE, SUITE 350
- **CITY:** BRENTWOOD
- **STATE:** TN
- **ZIP:** 37027
- **BUSINESS PHONE:** (949) 232-1900

**MAIL ADDRESS:**
- **STREET 1:** 112 WESTWOOD PLACE, SUITE 350
- **CITY:** BRENTWOOD
- **STATE:** TN
- **ZIP:** 37027

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CRYOPORT SYSTEMS LLC
- **DATE OF NAME CHANGE:** 20010614

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CRYOPORT SYSTEMS INC
- **DATE OF NAME CHANGE:** 20000923

**As filed with the Securities and Exchange Commission on June** **22, 2026**

**Registration No. 333-**

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**WASHINGTON, D.C. 20549**

**FORM S-8** 

**REGISTRATION STATEMENT**

***UNDER***

***THE SECURITIES ACT OF 1933***

 ****

 ****

**Cryoport, Inc.**

**(Exact name of registrant as specified in its charter)**

---

| | |
|:---|:---|
| &nbsp;&nbsp;**Nevada**<br> **(State or other jurisdiction of<br> incorporation or organization)** | &nbsp;&nbsp;**88-0313393**<br> **(I.R.S. Employer<br> Identification No.)** |

---

**112 Westwood Place, Suite 350 <br> Brentwood, TN 37027<br> (Address of principal executive offices, including zip code)**

**Cryoport, Inc. 2018 Omnibus Equity Incentive Plan**

**(Full title of the plan)**

**Robert Stefanovich<br> Cryoport, Inc.**

**Chief Financial Officer**

**112 Westwood Place, Suite 350**

**Brentwood, TN 37027**

**(949) 470-2300**

**(Name, address and telephone number, including area code, of agent for service)**

***With a copy to:***

**Kevin Zen**

**Snell & Wilmer L.L.P.**

**600 Anton Boulevard., Suite 1400**

**Costa Mesa, CA 92626**

**(714) 427-7000**

<br> Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

Large accelerated filer ◻ Accelerated filer ⌧ <br> Non-accelerated filer ◻ Smaller reporting company ◻ <br> Emerging growth company ◻

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ◻

**EXPLANATORY NOTE**

This registration statement is being filed solely for the registration of 4,275,000 additional shares of common stock, $0.001 par value per share, of Cryoport, Inc., a Nevada corporation (the "Company"), for issuance pursuant to the Cryoport, Inc. 2018 Omnibus Equity Incentive Plan (as amended, the "Plan"). Accordingly, pursuant to General Instruction E to Form S-8, the contents of the Company's prior registration statements relating to the Plan (Nos. [333-225387](https://www.sec.gov/Archives/edgar/data/1124524/000114420418032437/tv495652_s8.htm), [333-257368](https://www.sec.gov/Archives/edgar/data/1124524/000110465921085198/tm2119935d1_s8.htm) and [333-280227](https://www.sec.gov/Archives/edgar/data/1124524/000110465924071793/tm2417091d1_s8.htm)) are hereby incorporated by reference in this registration statement, except as revised in Part II of this registration statement.

**PART II<br> INFORMATION REQUIRED IN THE REGISTRATION STATEMENT**

**Item 3. Incorporation of Documents by Reference**.

The following documents filed by the Company with the Securities and Exchange Commission (the "Commission") are incorporated by reference into this registration statement and are deemed to be a part hereof from the date of filing:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. [The Company's Annual Report on Form 10-K for the year ended December 31, 2025, filed with the Commission on March 5, 2026 (the "Form 10-K").](https://www.sec.gov/ix?doc=/Archives/edgar/data/1124524/000110465926024180/cyrx-20251231x10k.htm)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. The
 Company's Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2026,
 filed with the Commission on [May 5, 2026](https://www.sec.gov/ix?doc=/Archives/edgar/data/1124524/000110465926055513/cyrx-20260331x10q.htm) .

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. The
 Company's Current Report on Form 8-K, filed with the Commission on [June 9, 2026](https://www.sec.gov/ix?doc=/Archives/edgar/data/1124524/000110465926071892/tm2617057d1_8k.htm) .

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4. The
 description of the Company's common stock contained in its Registration Statement on [Form 8-A (No. 001-34632), filed with the Commission on July 22, 2015](https://www.sec.gov/Archives/edgar/data/1124524/000114420415043537/v415833_8a12b.htm) , and any amendment or
 report filed for the purpose of updating such description, including Exhibit 4.1 to the Form
 10-K.

All documents filed by the Company pursuant to Section 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934, as amended (other than Current Reports on Form 8-K furnished under Item 2.02 or Item 7.01 of Form 8-K and exhibits furnished on such form that relate to such items), subsequent to the filing of this registration statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this registration statement and to be a part hereof from the date of filing such documents, except as to specific sections of such documents as set forth therein. Any statement contained in this registration statement or a previously filed document incorporated by reference will be deemed to be modified or superseded for purposes of this registration statement to the extent that a statement contained in this registration statement or a subsequently filed document incorporated by reference modifies or supersedes that statement.

**Item 8. Exhibits**.

---

| | | |
|:---|:---|:---|
| **Exhibit<br> Number** | **Description** | **Page or Method of Filing** |
| 4.1 | [Amended and Restated Articles of Incorporation of Cryoport, Inc.](https://www.sec.gov/Archives/edgar/data/1124524/000119312512463099/d399045dex31.htm) | Incorporated by reference to Exhibit 3.1 of the Company's Form 10-Q filed with the Commission on November 9, 2012 |
| 4.2 | [Amended and Restated Bylaws of Cryoport, Inc.](https://www.sec.gov/Archives/edgar/data/1124524/000114420416079609/v430817_ex3-1.htm) | Incorporated by reference to Exhibit 3.1 to the Company's Form 8-K filed with the Commission on February 8, 2016 |
| 4.3 | [Amended and Restated Certificate of Designation of Class A Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415019455/v405839_ex3-1.htm) | Incorporated by reference to Exhibit 3.1 to the Company's Current Report on Form 8-K filed with the Commission on March 30, 2015 |
| 4.4 | [Certificate of Designation of Class B Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415011144/v402375_ex3-1.htm) | Incorporated by reference to Exhibit 3.1 to the Company's Current Report on Form 8-K filed with the Commission on February 20, 2015 |

---

---

| | | |
|:---|:---|:---|
| **Exhibit<br> Number** | **Description** | **Page or Method of Filing** |
| 4.5 | [Amendment to Certificate of Designation of Class B Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415023607/v405583_ex3-6.htm) | Incorporated by reference to Exhibit 3.6 to the Company's Amendment No. 1 to Registration Statement on Form S-1 filed with the Commission on April 17, 2015 |
| 4.6 | [Certificate of Change filed with the Nevada Secretary of State on May 12, 2015](https://www.sec.gov/Archives/edgar/data/1124524/000114420415032332/v410289_ex3-7.htm) | Incorporated by reference to Exhibit 3.7 to the Company's Annual Report on Form 10-K filed with the Commission on May 19, 2015 |
| 4.7 | [Amendment to Certificate of Designation of Class A Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415038353/v413707_ex3-8.htm) | Incorporated by reference to Exhibit 3.8 to the Company's Amendment No. 4 to Registration Statement on Form S-1 filed with the Commission on June 22, 2015 |
| 4.8 | [Amendment to Certificate of Designation of Class B Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415038353/v413707_ex3-9.htm) | Incorporated by reference to Exhibit 3.9 to the Company's Amendment No. 4 to Registration Statement on Form S-1 filed with the Commission on June 22, 2015 |
| 4.9 | [Amendment to Certificate of Designation of Class A Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415053768/v419800_ex3-1.htm) | Incorporated by reference to Exhibit 3.1 to the Company's Current Report on Form 8-K filed with the Commission on September 4, 2015 |
| 4.10 | [Amendment to Certificate of Designation of Class B Preferred Stock](https://www.sec.gov/Archives/edgar/data/1124524/000114420415053768/v419800_ex3-2.htm) | Incorporated by reference to Exhibit 3.2 to the Company's Current Report on Form 8-K filed with the Commission on September 4, 2015 |
| 4.11 | [Certificate of Amendment filed with the Nevada Secretary of State on November 23, 2015](https://www.sec.gov/Archives/edgar/data/1124524/000114420415068672/v425935_ex3-1.htm) | Incorporated by reference to Exhibit 3.1 to the Company's Current Report on Form 8-K filed with the Commission on December 1, 2015 |
| 4.12 | [Certificate of Amendment filed with the Nevada Secretary of State on May 30, 2018](https://www.sec.gov/Archives/edgar/data/1124524/000114420419013692/tv515562_ex3-12.htm) | Incorporated by reference to Exhibit 3.12 of the Company's Annual Report on Form 10-K filed with the Commission on March 13, 2019 |
| 4.13 | [Certificate of Designation of 4.0% Series C Convertible Preferred Stock of Cryoport, Inc.](https://www.sec.gov/Archives/edgar/data/1124524/000110465920111047/tm2031885d1_ex3-1.htm) | Incorporated by reference to Exhibit 3.1 to the Company's Current Report on Form 8-K filed with the Commission on October 1, 2020 |
| 5.1 | [Opinion of Snell & Wilmer L.L.P.](tm2618162d1_ex5-1.htm) | Filed herewith |
| 23.1 | [Consent of Deloitte & Touche LLP, Independent Registered Public Accounting Firm](tm2618162d1_ex23-1.htm) | Filed herewith |

---

---

| | | |
|:---|:---|:---|
| **Exhibit<br> Number** | **Description** | **Page or Method of Filing** |
| 23.3 | [Consent of Snell & Wilmer L.L.P.](tm2618162d1_ex5-1.htm) | Included as part of Exhibit 5.1 |
| 24.1 | [Power of Attorney](#a_001) | Included on the signature page hereto |
| 99.1 | [Cryoport, Inc. 2018 Omnibus Equity Incentive Plan (as amended by the First Amendment, the Second Amendment, the Third Amendment and the Fourth Amendment, effective June 5, 2026)](https://www.sec.gov/Archives/edgar/data/1124524/000110465926071892/tm2617057d1_ex10-1.htm) | Incorporated by reference to Exhibit 10.1 to the Company's Current Report on Form 8-K filed with the Commission on June 9, 2026 |
| 107 | [Filing Fee Table](tm2618162d1_ex-filingfees.htm) | Filed herewith |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Brentwood, State of Tennessee, on June 22, 2026.

---

| | |
|:---|:---|
| **CRYOPORT, INC.** | **CRYOPORT, INC.** |
| By: | /s/ Robert S. Stefanovich |
| Name: | Robert S. Stefanovich |
| Title: | Chief Financial Officer |

---

**POWER OF ATTORNEY**

Each person whose signature appears below hereby constitutes and appoints Jerrell W. Shelton and Robert S. Stefanovich, and each of them, his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this registration statement, and to file the same, with any and all exhibits thereto, and other documents in connection therewith, with the Commission, and hereby grants to such attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.

---

| | | |
|:---|:---|:---|
| **<u>Signature</u>** | **<u>Title</u>** | **<u>Date</u>** |
| /s/ Jerrell W. Shelton | President, Chief Executive Officer and Director | June 22, 2026 |
| Jerrell W. Shelton | (Principal Executive Officer) |  |
| /s/ Robert S. Stefanovich | Chief Financial Officer | June 22, 2026 |
| Robert S. Stefanovich | (Principal Financial and Accounting Officer) |  |
| /s/ Daniel M. Hancock | Director | June 22, 2026 |
| Daniel M. Hancock |  |  |
| /s/ Robert Hariri, M.D., Ph.D. | Director | June 22, 2026 |
| Robert Hariri, M.D., Ph.D. |  |  |
| /s/ Ramkumar Mandalam, Ph.D. | Director | June 22, 2026 |
| Ramkumar Mandalam, Ph.D. |  |  |
| /s/ Ram Jagannath | Director | June 22, 2026 |
| Ram Jagannath |  |  |
| /s/ Linda Baddour | Director | June 22, 2026 |
| Linda Baddour |  |  |

---

## Exhibit 5.1

**EXHIBIT 5.1**

[Snell & Wilmer L.L.P. Letterhead]

June 22, 2026

Cryoport, Inc.<br> 112 Westwood Place, Suite 350<br> Brentwood, TN 37027

Ladies and Gentlemen:

We have examined the Registration Statement on Form S-8 (the "Registration Statement") of Cryoport, Inc., a Nevada corporation (the "Company"), to be filed with the Securities and Exchange Commission (the "Commission") on or about the date hereof, in connection with the registration under the Securities Act of 1933, as amended (the "Securities Act"), of 4,275,000 shares of the Company's common stock, $0.001 par value per share (the "Shares"), pursuant to the Cryoport, Inc. 2018 Omnibus Equity Incentive Plan (as amended, the "Plan").

We have examined the originals, or photostatic or certified copies, of such records of the Company and certificates of officers of the Company and of public officials and such other documents as we have deemed relevant and necessary as the basis for the opinions set forth below. In our examination, we have assumed the genuineness of all signatures, the legal capacity and competency of all natural persons, the authenticity of all documents submitted to us as originals and the conformity to original documents of all documents submitted to us as copies. We are opining herein as to the Nevada Revised Statutes, and we express no opinion with respect to any other laws.

Based upon the foregoing examination and in reliance thereon, and subject to the assumptions stated and in reliance on statements of fact contained in the documents that we have examined, we are of the opinion that the Shares have been duly authorized and, when issued in accordance with the terms of the Plan against payment therefor, will be validly issued, fully paid and non-assessable.

We consent to the filing of this opinion as an exhibit to the Registration Statement. In giving such consent, we do not thereby admit that we are within the category of persons whose consent is required under Section 7 of the Securities Act or the Rules and Regulations of the Commission.

---

| |
|:---|
| Very truly yours, |
| /s/ Snell & Wilmer L.L.P. |

---

## Exhibit 23.1

**EXHIBIT 23.1**

**CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM**

We consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 5, 2026, relating to the financial statements of Cryoport, Inc. and the effectiveness of Cryoport, Inc.'s internal control over financial reporting, appearing in the Annual Report on Form 10-K of Cryoport, Inc. for the year ended December 31, 2025.

/s/ Deloitte & Touche LLP

Nashville, Tennessee

June 22, 2026

## Ex-Filing

?xml version='1.0' encoding='ASCII'? EX-FILING FEES

---

| |
|:---|
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Calculation of Filing Fee Tables**  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **S-8**  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Cryoport, Inc.**  |

---

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Security Type**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Security Class Title**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Fee Calculation Rule**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Amount Registered**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Proposed Maximum Offering Price Per Unit**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Maximum Aggregate Offering Price**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Fee Rate**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Amount of Registration Fee**  |
| 1 | Equity | Common Stock, $0.001 par value per share | Other | 4275000 | $14.76 | $63099000.00 | 0.0001381 | $8713.97 |
| Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: |  | $63099000.00  |  | $8713.97  |
| Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  |  |  |  | $0.00  |
| Net Fee Due:  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  |  |  |  | $8713.97  |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Offering Note** <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <sup>1</sup> (a) Represents an additional 4,275,000 shares of the registrant's common stock, $0.001 par value per share ("Common Stock"), reserved for issuance under the Cryoport, Inc. 2018 Omnibus Equity Incentive Plan (as amended, the "Plan"). (b) Pursuant to Rule 416(a) promulgated under the Securities Act of 1933, as amended (the "Securities Act"), this registration statement shall also cover any additional shares of Common Stock as may be issuable under the Plan as a result of stock splits, stock dividends or similar transactions. (c) The Proposed Maximum Offering Price Per Unit has been estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(h) and Rule 457(c) promulgated under the Securities Act based upon the average of the high and low prices of the Common Stock as reported on The Nasdaq Capital Market on June 16, 2026, which is a date within five business days prior to filing the registration statement.

---

| |
|:---|
| |
| **Rule 457(p)** |
| Fee Offset Claims |
| Fee Offset Sources |

---