# EDGAR Filing Document

**Accession Number:** 0001778016
**File Stem:** 0001193125-25-256922
**Filing Date:** 2025-10
**Character Count:** 16845
**Document Hash:** 0c4368400fa68c4312fae26372bffc0b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-256922.hdr.sgml**: 20251030

**ACCESSION NUMBER**: 0001193125-25-256922

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 3

**CONFORMED PERIOD OF REPORT**: 20251029

**FILED AS OF DATE**: 20251030

**DATE AS OF CHANGE**: 20251029

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** NovaBridge Biosciences
- **CENTRAL INDEX KEY:** 0001778016
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-39173
- **FILM NUMBER:** 251431581

**BUSINESS ADDRESS:**
- **STREET 1:** SUITE 400, 2440 RESEARCH BLVD
- **CITY:** ROCKVILLE
- **STATE:** MD
- **ZIP:** 20850
- **BUSINESS PHONE:** (301) 670 2800

**MAIL ADDRESS:**
- **STREET 1:** SUITE 400, 2440 RESEARCH BLVD
- **CITY:** ROCKVILLE
- **STATE:** MD
- **ZIP:** 20850

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** I-Mab
- **DATE OF NAME CHANGE:** 20190528

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**WASHINGTON, D.C. 20549**

**FORM 6-K**

**REPORT OF FOREIGN PRIVATE ISSUER**

**PURSUANT TO RULE 13a-16 OR 15d-16 UNDER**

**THE SECURITIES EXCHANGE ACT OF 1934**

For the month of October 2025

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Commission File Number: 001-39173

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**NovaBridge Biosciences**

2440 Research Boulevard, Suite 400

Rockville, MD 20850

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒ Form 40-F ☐

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**Assignment and Assumption Agreement between Visara, Inc, ("Visara") and Everest Medicines (Singapore) Pte. Ltd., ("Everest")**

On October 28, 2025, Visara, a subsidiary of NovaBridge Biosciences, f/k/a I-MAB, ("NovaBridge" or the "Company") entered into an Assignment and Assumption Agreement (the "Assignment and Assumption Agreement") with Everest pursuant to which Visara has agreed to assign, and Everest has agreed to assume, all of the rights and obligations of Visara under the Exclusive License Agreement, dated October 15, 2025 between Visara and AskGene Pharma, Inc. ("AskGene").

**Directorate Change**

On October 15, 2025, the board of directors (the "Board") of NovaBridge Biosciences, f/k/a I-MAB, ("NovaBridge" or the "Company") appointed Mr. Ian Ying Woo as independent members of the Board, effective immediately. Mr. Woo has also been appointed as a member of the Nominating and Corporate Governance Committee of the Board.

Mr. Woo is President, Chief Financial Officer and Director of Everest Medicines Limited (HKEX: 1952). and also serves as an operating partner of CBC Group. He has recently served as an independent director and chairman of the audit committee of Prenetics Global Limited (Nasdaq: PRE). From 2018 to 2019, Mr. Woo served as Managing Director of CBC Group. Prior to that,from 2005 to 2018, Mr. Woo was a Managing Director in the global healthcare group of Lazard Frères & Co. LLC, working in the New York and Hong Kong offices. Mr. Woo earned his Master of Business Administration from the Columbia University Graduate School of Business, his Master of Arts in Cellular, Molecular and Biomedical studies from the Columbia University Graduate School of Arts and Sciences, and his Bachelor of Science in Biology from Tufts University.

Mr. Woo will be entitled to applicable cash retainer fees and an initial and annual equity grant pursuant to the Company's Non-Executive Director Compensation Policy. Mr. Woo has entered into the Company's standard form of indemnification agreement, the form of which is filed as Exhibit 10.3 to the Company's Registration Statement on Form F-1 (File No. 333-234363), as amended, initially filed with the SEC on October 29, 2019. There are no arrangements or understandings between Mr. Woo and any other persons pursuant to which they were appointed as directors.

A copy of the press release is attached hereto as Exhibit 99.1.

**Incorporation by Reference**

A copy of the full text of the press release referenced above is filed as Exhibit 99.1 hereto and is incorporated herein by reference. The information set forth in this Report on Form 6-K shall be deemed to be incorporated by reference into the Company's Registration Statements on Form F-3 (File No. 333-286954) and Form S-8 (File No. 333-239871, File No. 333-256603, File No. 333-265684, File No. 333-279842 and File No. 333-290195) (including any prospectuses forming a part of such registration statements) and to be a part thereof from the date on which this Form 6-K is furnished, to the extent not superseded by documents or reports subsequently filed or furnished.

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**EXHIBIT INDEX**

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| | |
|:---|:---|
| **<u>Exhibit No.</u>** | **<u>Description</u>** |
| [<u>99.1</u>](imab-ex99_1.htm) | [<u>Press Release - NovaBridge Subsidiary Visara Assigns Its Exclusive License to Everest Medicines for VIS-101 in Greater China and Certain Other Asian Countries</u>](imab-ex99_1.htm) |

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

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| | | |
|:---|:---|:---|
| NovaBridge Biosciences | NovaBridge Biosciences | NovaBridge Biosciences |
| By | : | /s/ Xi-Yong Fu |
| Name | : | Xi-Yong (Sean) Fu |
| Title | : | Chief Executive Officer |

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Date: October 29, 2025

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## Exhibit 99.1

**Exhibit 99.1**

![img44095488_0.jpg](img44095488_0.jpg)

**NovaBridge Subsidiary Visara Assigns Its Exclusive License to Everest Medicines for VIS-101 in Greater China and Certain Other Asian Countries**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•NovaBridge subsidiary Visara assigned its exclusive license to Everest Medicines to accelerate the development of potential best-in-class therapy for wet AMD, VIS-101, leveraging Everest Medicines' strong clinical and commercialization expertise in Greater China and other Asian markets

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•NovaBridge also named Mr. Ian Woo, President and Chief Financial Officer of Everest Medicines, to its Board of Directors, bringing substantial expertise in international biopharma finance, operations and management

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•VIS-101 is a novel bifunctional biologic targeting VEGF-A/ANG2, with potential to provide more effective and durable treatment than the current standard of care for patients with wet AMD, DME and RVO. The program is completing a Phase 2 study in China and is expected to be Phase-3-ready in 2026

ROCKVILLE, MD, October 29, 2025 – NovaBridge Biosciences (Nasdaq: NBP) (NovaBridge or the Company) a global biotechnology platform company committed to accelerating access to innovative medicines, today announced that its subsidiary Visara, Inc. (Visara) has assigned it exclusive license agreement to Everest Medicines (HKEX: 1952) for the development, manufacture and commercialization of VIS-101, a novel bifunctional biologic targeting VEGF-A and ANG-2, in Greater China, and certain other Asian countries In addition, NovaBridge has appointed Mr. Ian Woo to its Board of Directors (the Board).

"This Agreement with Everest Medicines is an excellent fit with NovaBridge's focus on collaborating with global innovators to accelerate the development of novel medicines such as VIS-101," said **Sean Fu, PhD, Chief Executive Officer of NovaBridge**. "In addition, I believe Ian's extensive track record in strategic transactions, operations and management will be a valuable asset to NovaBridge as we work to accelerate the global development of transformative medicines and create value for patients and investors."

"Everest Medicines' clinical and commercial expertise could enable us to accelerate the development and bring VIS-101 to patients across Asia sooner," said **Emmett T. Cunningham, Jr. MD, PhD, MPH, Co-Founder and Executive Chairman** of Visara. "With its unique potency and potential to provide more durable treatment benefits, we believe VIS-101 has a robust opportunity to be a second-in-class with best-in-class potential treatment for patients around the world with wet AMD, DME and RVO."

"Partnering with Visara brings a highly differentiated and commercially attractive asset to Everest's late-stage pipeline and paves the way for our entry into the ophthalmology market, an area of significant unmet need," said **Ian Woo, President and Chief Financial Officer** of Everest Medicines. "We are pleased to leverage our core clinical development and commercialization expertise to advance VIS-101 in Greater China and across Asia."

As previously reported, through an assignment agreement with AffaMed and a direct license with AskGene, Visara acquired exclusive rights for VIS-101 globally. Visara has assigned its direct license with AskGene to Everest Medicines to develop, manufacturing and commercialize VIS-101 in Greater China, Singapore, South Korea, and certain Southeast Asian countries. Everest will assume all payment obligations under the assigned license agreement and reimburse Visara any upfront payment it has already made.

**About Ian Woo**

Mr. Ian Ying Woo is an experienced biopharma finance professional bringing substantial strategy, capital markets and operations and management expertise to NovaBridge. Currently, Mr. Woo is President, Chief Financial Officer and Director

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of Everest Medicines Limited (HKEX: 1952), and also serves as an operating partner of CBC Group. He has recently served as an independent director and chairman of the audit committee of Prenetics Global Limited (Nasdaq: PRE). Before that, Mr. Woo's held the role of managing director of CBC Group. Prior to that, Mr. Woo was a managing director in the global healthcare group of Lazard Frères & Co. LLC, working in the New York and Hong Kong offices. Throughout his investment banking career, Mr. Woo helped to raise over US$1 billion in equity financings and advised on merger and acquisition transactions aggregating more than US$35 billion in value. Mr. Woo received his Bachelor of Science in Biology from Tufts University, his Master of Arts in Cellular, Molecular and Biomedical studies from the Columbia University Graduate School of Arts and Sciences and his Master of Business Administration from the Columbia University Graduate School of Business.

**About VIS-101**

VIS-101 is a novel bifunctional biologic targeting VEGF-A and ANG-2, and a more potent molecule that could potentially provide more durable treatment benefits for patients with wet age-related macular degeneration (wet AMD), diabetic macular edema (DME) and retinal vein occlusion (RVO) than current standard of care. VIS-101 has completed initial safety and dose-escalation studies in both the US and China, and is currently completing a randomized, dose-ranging Phase 2 study in China. VIS-101 is anticipated to be Phase 3-ready in 2026.

**About Visara, Inc.** 

Visara is a clinical-stage biopharmaceutical company focusing on the development of best-in-class ophthalmic therapeutics. The Company is led by Co-Founder and Executive Chairman Emmett T. Cunningham, Jr., MD, PhD, MPH, a physician, innovator, entrepreneur, and investor and internationally recognized specialist in infectious and inflammatory eye disease. NovaBridge is the majority shareholder of Visara, and Visara controls global rights to VIS-101, outside of Greater China and certain countries in Asia.

**About NovaBridge**

NovaBridge is a global biotechnology platform company committed to accelerating access to innovative medicines. We combine deep business development expertise with agile translational clinical development to identify, accelerate, and advance breakthrough assets. By bridging science, strategy, and execution, NovaBridge enables transformative therapies to progress rapidly from discovery toward patients in need.

The Company's differentiated pipeline is led by givastomig, a potential best-in-class, bispecific antibody (Claudin 18.2 x 4-1BB), and VIS-101, a second-in-class, potentially best-in-class bifunctional biologic, targeting VEGF-A and ANG2.

Givastomig conditionally activates T cells via the 4-1BB signaling pathway in the tumor microenvironment where Claudin 18.2 is expressed. Givastomig is being developed to treat Claudin 18.2-positive gastric cancer and other gastrointestinal malignancies. The Company is also collaborating with its partner, ABL Bio, for the development of ragistomig, a bispecific antibody integrating PD-L1 as a tumor engager and 4-1BB as a conditional T cell activator, in solid tumors. Additionally, NovaBridge owns worldwide rights outside of China to uliledlimab, an anti-CD73 antibody that targets adenosine-driven immunosuppression in cancer.

VIS-101 targets VEGF-A and ANG-2 to provide more potent and durable treatment benefits for patients with wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME). VIS-101 is currently completing a large, randomized, dose-ranging Phase 2 study for wet AMD. NovaBridge is the majority shareholder of Visara, and Visara controls global rights to VIS-101, outside of Greater China and certain countries in Asia.

For more information, please visit <u>https://www.novabridge.com</u> and follow us on LinkedIn.

**Forward Looking Statements** 

This announcement contains forward-looking statements. These statements are made under the "safe harbor" provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will", "expects", "believes", "designed to", "anticipates", "future", "intends", "plans", "potential", "estimates", "confident", and similar terms or the negative thereof. NovaBridge may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities and Exchange Commission (the SEC), in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or

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employees to third parties. Statements that are not historical facts, including statements about the Company's beliefs and expectations, are forward-looking statements. Forward-looking statements in this press release include, without limitation, statements regarding: the potential benefits of the collaboration with Everest Medicines; the strategy, clinical development, plans, results, safety and efficacy of givastomig and VIS-101 and its other drug candidates; the strategic and clinical development of NovaBridge's drug candidates, including givastomig and VIS-101; anticipated clinical milestones and results, and related timing. Forward-looking statements involve inherent risks and uncertainties that may cause actual results to differ materially from those contained in these forward-looking statements, including but not limited to the following: the Company's ability to demonstrate the safety and efficacy of its drug candidates; the clinical results for its drug candidates, which may or may not support further development or New Drug Application/Biologics License Application (NDA/BLA) approval; the content and timing of decisions made by the relevant regulatory authorities regarding regulatory approval of the Company's drug candidates; the Company's ability to achieve commercial success for its drug candidates, if approved; the Company's ability to obtain and maintain protection of intellectual property for its technology and drugs; the Company's reliance on third parties to conduct drug development, manufacturing and other services; the Company's limited operating history and the Company's ability to obtain additional funding for operations and to complete the development and commercialization of its drug candidates; and those risks more fully discussed in the "Risk Factors" section in the Company's annual report on Form 20-F filed with the SEC on April 3, 2025 as well as the discussions of potential risks, uncertainties, and other important factors in the Company's subsequent filings with the SEC. All forward-looking statements are based on information currently available to the Company. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise, except as may be required by law.

**NovaBridge Investor & Media Contacts**

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| | |
|:---|:---|
| PJ Kelleher | Kyler Lei |
| LifeSci Advisors | NovaBridge |
| +1-617-430-7579 | +1-240-745-6330 |
| pkelleher@lifesciadvisors.com | kyler.lei@imabbio.com |
|  | IR@imabbio.com |

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