# EDGAR Filing Document

**Accession Number:** 0001781983
**File Stem:** 0001104659-25-057807
**Filing Date:** 2025-6
**Character Count:** 8286
**Document Hash:** 084e4f737977faab522822e229cf2ca7
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-057807.hdr.sgml**: 20250609

**ACCESSION NUMBER**: 0001104659-25-057807

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 12

**CONFORMED PERIOD OF REPORT**: 20250605

**ITEM INFORMATION**: Submission of Matters to a Vote of Security Holders

**FILED AS OF DATE**: 20250609

**DATE AS OF CHANGE**: 20250609

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Aprea Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001781983
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-39069
- **FILM NUMBER:** 251033919

**BUSINESS ADDRESS:**
- **STREET 1:** 3805 OLD EASTON ROAD
- **CITY:** DOYLESTOWN
- **STATE:** PA
- **ZIP:** 18902
- **BUSINESS PHONE:** 215-948-4119

**MAIL ADDRESS:**
- **STREET 1:** 3805 OLD EASTON ROAD
- **CITY:** DOYLESTOWN
- **STATE:** PA
- **ZIP:** 18902

?xml version='1.0' encoding='ASCII'?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d)**

**of the Securities Exchange Act of 1934**

**June 5, 2025** 

Date of Report (Date of earliest event reported)

**Aprea Therapeutics, Inc.**

(Exact name of registrant as specified in its charter)

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;**Delaware** | &nbsp;&nbsp;**001-39069** | &nbsp;&nbsp;**001-39069** | &nbsp;&nbsp;**84-2246769** |
| &nbsp;&nbsp;(State or other jurisdiction<br> of incorporation) | &nbsp;&nbsp;(Commission<br> File Number) | &nbsp;&nbsp;(Commission<br> File Number) | &nbsp;&nbsp;(IRS Employer<br> Identification No.) |
| &nbsp;&nbsp;**3805 Old Easton Road**<br> **Doylestown** **, PA**<br> (Address of principal executive offices) | &nbsp;&nbsp;**3805 Old Easton Road**<br> **Doylestown** **, PA**<br> (Address of principal executive offices) | &nbsp;&nbsp;<br> **18902**<br> (Zip Code) | &nbsp;&nbsp;<br> **18902**<br> (Zip Code) |

---

&nbsp;&nbsp;Registrant's telephone number, including area code: **(215) 948-4119**<br>(Former name or former address, if changed since last report):<br>

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

◻ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

◻ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

◻ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

◻ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| **Title of each class** | **Trading Symbol(s)** | **Name of each exchange on** <br> **which registered**  |
| Common stock, par value $0.001 per share | APRE | The NASDAQ Stock Market LLC |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ◻

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ◻

---

| | |
|:---|:---|
| **Item 5.07** | **Submission of Matters to a Vote of Security Holders.** |

---

At the 2025 annual meeting of stockholders (the "Annual Meeting") of the Aprea Therapeutics, Inc. (the "Company") held on June 5, 2025, the following proposals were submitted to the stockholders of the Company:

Proposal 1: A proposal to elect three Class III directors of the Company, Jean-Pierre Bizzari, M.D., Oren Gilad, Ph.D. and John B. Henneman III, each to hold office until the 2028 Annual Meeting of Stockholders or until their successors shall have been duly elected and qualified.

Proposal 2: A proposal to ratify the appointment of EisnerAmper LLP as the Company's independent registered public accounting firm for the 2025 fiscal year.

---

| | |
|:---|:---|
| Proposal 3: | A proposal to approve, by non-binding advisory vote, the compensation of our named executive officers. |

---

---

| | |
|:---|:---|
| Proposal 4: | A proposal to approve, by non-binding advisory vote, the frequency of future votes on the compensation of our named executive officers. |

---

For more information about the foregoing proposals, see the Company's definitive proxy statement on Schedule 14A filed with the United States Securities and Exchange Commission on April 22, 2025. Of the 5,525,172 shares of the Company's common stock entitled to vote at the Annual Meeting, 3,817,718 shares, or approximately 69.09%, were represented at the Annual Meeting in person or by proxy, constituting a quorum. The number of votes cast for, against or withheld, as well as abstentions and broker non-votes, if applicable, in respect of each such proposal is set forth below.

Proposal 1: Election of Class III Directors.

The Company's stockholders elected the following directors to serve as Class III directors until the 2028 Annual Meeting of Stockholders of the Company or until their successors are duly elected and qualified. The votes regarding the election of the directors were as follows:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Director** | **Votes For** | **Votes For** | **Votes Withheld** | **Votes Withheld** | **Broker Non-Votes** | **Broker Non-Votes** |
| Jean-Pierre Bizzari, M.D. |  | 2455322 |  | 82783 |  | 1279613 |
| Oren Gilad, Ph.D. |  | 2438369 |  | 99736 |  | 1279613 |
| John B. Henneman III |  | 2426358 |  | 111747 |  | 1279613 |

---

Proposal 2: Ratification of Appointment EisnerAmper LLP.

The Company's stockholders ratified the appointment of EisnerAmper LLP as the Company's independent registered public accounting firm for the fiscal year 2025. The votes regarding this proposal were as follows:

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| **Votes For** | **Votes For** | **Votes Against** | **Votes Against** | **Votes Abstaining** | **Votes Abstaining** | **Broker Non-Votes** | **Broker Non-Votes** |
|  | 2916782 |  | 49535 |  | 35669 |  | 0 |

---

---

| | |
|:---|:---|
| Proposal 3: | Approval, by non-binding advisory vote, the compensation of our named executive officers. |

---

The Company's stockholders voted to approve, by non-binding advisory vote, the compensation of the Company's named executive officers. The votes regarding this proposal were as follows:

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| **Votes For** | **Votes For** | **Votes Against** | **Votes Against** | **Votes Abstaining** | **Votes Abstaining** | **Broker Non-Votes** | **Broker Non-Votes** |
|  | 1628716 |  | 58828 |  | 34829 |  | 1279613 |

---

---

| | |
|:---|:---|
| Proposal 4: | Approval, by non-binding advisory vote, the compensation of our named executive officers. |

---

The Company's stockholders voted to approve, by non-binding advisory vote, the frequency of future votes on the compensation of our named executive officers. The votes regarding this proposal were as follows:

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| **1 Year** | **1 Year** | **2 Years** | **2 Years** | **3 Years** | **3 Years** | **Votes Abstaining** | **Votes Abstaining** |
|  | 1159068 |  | 1464 |  | 553310 |  | 8531 |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this Report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
| Date: June 9, 2025 | **Aprea Therapeutics, Inc.** | **Aprea Therapeutics, Inc.** |
|  | By: | /s/ Oren Gilad |
|  |  | Oren Gilad, Ph.D., |
|  |  | President and Chief Executive Officer |

---