# EDGAR Filing Document

**Accession Number:** 0001716947
**File Stem:** 0001493152-23-001391
**Filing Date:** 2023-1
**Character Count:** 2505
**Document Hash:** cfbb541add58a0e7f650321d67908f24
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001493152-23-001391.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0001493152-23-001391

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230113

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Ensysce Biosciences, Inc.
- **CENTRAL INDEX KEY:** 0001716947
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 822755287
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 7946 IVANHOE AVENUE
- **STREET 2:** SUITE 201
- **CITY:** LA JOLLA
- **STATE:** CA
- **ZIP:** 92037
- **BUSINESS PHONE:** (858) 263-4196

**MAIL ADDRESS:**
- **STREET 1:** 7946 IVANHOE AVENUE
- **STREET 2:** SUITE 201
- **CITY:** LA JOLLA
- **STATE:** CA
- **ZIP:** 92037

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Leisure Acquisition Corp.
- **DATE OF NAME CHANGE:** 20170913

**Ensysce Biosciences, Inc.**

**7946 Ivanhoe Avenue, Suite 201**

**La Jolla, California 92037**

January 13, 2023

**VIA EDGAR**

U.S. Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, NE

Washington, D.C. 20549

Attention: Tyler Howes, Esq.

Re: Ensysce Biosciences, Inc. <br> Registration Statement on Form S-3 <br> SEC File No. 333-269157

Ladies and Gentlemen:

Pursuant to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, Ensysce Biosciences, Inc. (the "**Company**") hereby requests that the effective date of the Company's Registration Statement on Form S-3 (File No. 333-269157) (the "**Registration Statement**") be accelerated to 4:00 PM, Eastern Time, on Tuesday, January 17, 2023, or as soon thereafter as is practicable, or at such other time thereafter as our counsel, Troutman Pepper Hamilton Sanders LLP, may request by telephone. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel by calling Gregory Rubis, Esq. at (609) 951-4105.

Please direct any questions or comments concerning this request to Mr. Rubis of Troutman Pepper Hamilton Sanders LLP.

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| | |
|:---|:---|
| **ENSYSCE BIOSCIENCES, INC.** | **ENSYSCE BIOSCIENCES, INC.** |
| By: | */s/ Lynn Kirkpatrick* |
| Name: | Lynn Kirkpatrick |
| Title: | CEO |

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Cc: Eric D. Kline, Troutman Pepper Hamilton Sanders LLP <br> Gregory Rubis, Troutman Pepper Hamilton Sanders LLP