# EDGAR Filing Document

**Accession Number:** 0000203596
**File Stem:** 0001193125-26-173922
**Filing Date:** 2026-4
**Character Count:** 52074
**Document Hash:** 00a077bd09460f1ec13903a894ee0d1b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-173922.hdr.sgml**: 20260423

**ACCESSION NUMBER**: 0001193125-26-173922

**CONFORMED SUBMISSION TYPE**: S-8 POS

**PUBLIC DOCUMENT COUNT**: 4

**FILED AS OF DATE**: 20260423

**DATE AS OF CHANGE**: 20260423

**EFFECTIVENESS DATE**: 20260423

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** WESBANCO INC
- **CENTRAL INDEX KEY:** 0000203596
- **STANDARD INDUSTRIAL CLASSIFICATION:** NATIONAL COMMERCIAL BANKS [6021]
- **ORGANIZATION NAME:** 02 Finance
- **EIN:** 550571723
- **STATE OF INCORPORATION:** WV
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8 POS
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-255443
- **FILM NUMBER:** 26889399

**BUSINESS ADDRESS:**
- **STREET 1:** 1 BANK PLAZA
- **CITY:** WHEELING
- **STATE:** WV
- **ZIP:** 26003
- **BUSINESS PHONE:** 3042349000

**MAIL ADDRESS:**
- **STREET 1:** ONE BANK PLZ
- **CITY:** WHEELING
- **STATE:** WV
- **ZIP:** 26003

**Registration No. 333-107736** 

**Registration No. 333-166541** 

**Registration No. 333-217398** 

**Registration No. 333-255443** 

**Registration No. 333-278833** 

**As filed with the Securities and Exchange Commission on April 23, 2026** 

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**WASHINGTON, DC 20549** 

**POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 (REGISTRATION NO. 333-107736)** 

**POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 (REGISTRATION NO. 333-166541)** 

**POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 (REGISTRATION NO. 333-217398)** 

**POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 (REGISTRATION NO. 333-255443)** 

**POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 (REGISTRATION NO. 333-278833)** 

**FORM S-8** 

**REGISTRATION STATEMENT** 

***UNDER***

***THE SECURITIES ACT OF 1933***

## WESBANCO, INC.
**(Exact name of registrant as specified in its charter)** 

---

| | |
|:---|:---|
| **West Virginia** | **55-0571723** |
| **(State or other jurisdiction of**<br> **incorporation or organization)** | **(I.R.S. Employer**<br> **Identification No.)** |

---

**One Bank Plaza** 

**Wheeling, West Virginia 26003** 

**(Address of principal executive offices)** 

**WESBANCO, INC. AMENDED AND RESTATED INCENTIVE BONUS,** 

**OPTION AND RESTRICTED STOCK PLAN** 

**WESBANCO, INC. 2026 EQUITY INCENTIVE PLAN** 

**(Full title of the plan)** 

**Richard Laws, Esq.** 

**Senior Executive Vice President and Chief Legal Counsel** 

**Wesbanco, Inc.** 

**One Bank Plaza** 

**Wheeling, West Virginia 26003** 

**(304) 234-9000** 

**(Name, address, including zip code, and telephone number, including area code, of agent for service)** 

***Copies to:***

---

| | |
|:---|:---|
| **James C. Gardill, Esq.**<br> **Phillips, Gardill, Kaiser & Altmeyer, PLLC**<br> **61 Fourteenth Street**<br> **Wheeling, WV 26003**<br> **(304) 232-6810** | **Jeffrey W. Acre, Esq.**<br> **K&L Gates LLP**<br> **K&L Gates Center**<br> **210 Sixth Avenue**<br> **Pittsburgh, PA 15222**<br> **(412) 355-6500** |

---

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

---

| | | | |
|:---|:---|:---|:---|
| Large accelerated filer | ☒ | Accelerated filer | ☐ |
| Non-accelerated filer | ☐ | Smaller reporting company | ☐ |
|  |  | Emerging growth company | ☐ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

------

**EXPLANATORY NOTE** 

This is (i) Post-Effective Amendment No. 1 to the Registration Statement on Form S-8 (File No. 333-107736) (the "2003 Form S-8"), filed by Wesbanco, Inc. (the "Registrant") with the Securities and Exchange Commission (the "Commission") on August 7, 2003, relating to the Wesbanco, Inc. Incentive Bonus, Option and Restricted Stock Plan (the "Prior Plan"); (ii) Post-Effective Amendment No. 1 to the Registration Statement on Form S-8 (File No. 333-166541) (the "2010 Form S-8"), filed by the Registrant with the Commission on May 5, 2010, relating to the Prior Plan; (iii) Post-Effective Amendment No. 1 to the Registration Statement on Form S-8 (File No. 333-217398) (the "2017 Form S-8"), filed by the Registrant with the Commission on April 20, 2017, relating to the Prior Plan; (iv) Post-Effective Amendment No. 1 to the Registration Statement on Form S-8 (File No. 333-255443) (the "2021 Form S-8"), filed by the Registrant with the Commission on April 22, 2021, relating to the Prior Plan; and (v) Post-Effective Amendment No. 1 to the Registration Statement on Form S-8 (File No. 333-278833) (the "2024 Form S-8"), filed by the Registrant with the Commission on April 19, 2024, relating to the Prior Plan.

On April 15, 2026 (the "Effective Date"), the Registrant's shareholders approved the Wesbanco, Inc. 2026 Equity Incentive Plan (the "2026 Plan"). Under the terms of the 2026 Plan, no further awards may be made under the Prior Plan as of the Effective Date. Contemporaneously with the filing of this Post-Effective Amendment, the Registrant is filing a Registration Statement on Form S-8 with the Commission to register the offer and sale of 1,665,046 newly authorized shares under the 2026 Plan.

As of the Effective Date, (i) an aggregate of 3,006,400 shares of Common Stock were issued by the Registrant pursuant to vested awards granted under the Prior Plan, (ii) 1,579,898 shares of Common Stock were subject to outstanding awards under the Prior Plan, and (iii) 1,313,702 shares of Common Stock were available for the granting of awards under the Prior Plan. An aggregate of 1,772,378 shares, consisting of (i) 1,579,898 shares of Common Stock which were subject to outstanding awards under the Prior Plan as of the Effective Date and (ii) 192,480 shares of Common Stock which will remain in the Prior Plan to satisfy dividend equivalent rights on awards outstanding under the Prior Plan on such date and related to dividends and distributions to be paid after such date, would become available for issuance under the 2026 Plan if such related awards subsequent to the Effective Date are terminated or cancelled without having been exercised or are forfeited, cancelled or repurchased by the Registrant (to the extent of such termination, cancellation, forfeiture or repurchase).

The 2003 Form S-8, the 2010 Form S-8 and the 2017 Form S-8 registered the offer and sale of an aggregate of 2,800,000 shares of Common Stock. All shares of Common Stock covered by each of the 2003 Form S-8, the 2010 Form S-8 and the 2017 Form S-8 were offered and sold pursuant thereto. The Registrant is filing Post-Effective Amendment No. 1 to the 2003 Form S-8, Post-Effective Amendment No. 1 to the 2010 Form S-8 and Post Effective Amendment No. 1 to the 2017 Form S-8 to reflect that the offering and sale of shares of Common Stock under each such registration statement has been terminated.

------

The 2021 Form S-8 registered the offer and sale of 2,000,000 shares of Common Stock. As of the Effective Date, (i) 206,400 shares of Common Stock covered by the 2021 Form S-8 were offered and sold pursuant thereto by means of vested awards granted under the Prior Plan; (ii) 1,579,898 shares of Common Stock covered by the 2021 Form S-8 were subject to outstanding awards under the Prior Plan; and (iii) 213,702 shares of Common Stock covered by the 2021 Form S-8 remained available for offer and sale pursuant thereto. In addition to the 1,579,898 shares of Common Stock covered by the 2021 Form S-8 that were subject to outstanding awards under the Prior Plan as of the Effective Date, 192,480 shares of Common Stock covered by the 2021 Form S-8 will remain in the Prior Plan to satisfy dividend equivalent rights on outstanding awards under the Prior Plan on such date and related to dividends and distributions to be paid after such date. Pursuant to the undertaking in Item 512(a)(1)(iii) of Regulation S-K that the Registrant disclose a material change in the plan of distribution, and pursuant to the Commission's Corporation Finance Interpretation Question 126.43, the Registrant is filing this Post-Effective Amendment No. 1 to the 2021 Form S-8 to reflect that (a) 213,702 shares of Common Stock that remained available for offer and sale pursuant to the 2021 Form S-8 as of the Effective Date instead may be offered and sold under the 2026 Plan, and (b) up to 1,772,378 shares of Common Stock, consisting of (1) up to 1,579,898 shares of Common Stock that are currently subject to outstanding awards under the Prior Plan and (2) up to 192,480 shares of Common Stock being retained for availability under the Prior Plan to satisfy dividend equivalent rights on awards outstanding under the Prior Plan on the Effective Date and related to dividends and distributions to be paid after the Effective Date, instead be offered and sold under the 2026 Plan if such awards subsequent to the Effective Date are terminated or cancelled without having been exercised or are forfeited, cancelled or repurchased by the Registrant (to the extent of such termination, cancellation, forfeiture or repurchase).

The 2024 Form S-8 registered the offer and sale of 1,100,000 shares of Common Stock. As of the Effective Date, (i) no shares of Common Stock covered by the 2024 Form S-8 were offered and sold pursuant thereto; (ii) no shares of Common Stock covered by the 2021 Form S-8 were subject to outstanding awards under the Prior Plan; and (iii) 1,100,000 shares of Common Stock covered by the 2024 Form S-8 remained available for offer and sale pursuant thereto. Pursuant to the undertaking in Item 512(a)(1)(iii) of Regulation S-K that the Registrant disclose a material change in the plan of distribution, and pursuant to the Commission's Corporation Finance Interpretation Question 126.43, the Registrant is filing this Post-Effective Amendment No. 1 to the 2021 Form S-8s to reflect that 1,100,000 shares of Common Stock that remained available for offer and sale pursuant to the 2021 Form S-8 as of the Effective Date instead may be issued under the 2026 Plan.

------

**PART I** 

**INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS** 

**ITEM 1. PLAN INFORMATION.\*** 

**ITEM 2. REGISTRANT INFORMATION AND EMPLOYEE PLAN INFORMATION\*** 

**\*** Information required by Part I to be contained in the Section 10(a) prospectus is omitted from this Post-Effective Amendment in accordance with Rule 428 under the Securities Act of 1933, as amended (the "Securities Act"), and the Note to Part I of Form S-8. The document containing the information specified in Part I will be delivered to the participants in the Prior Plan and the 2026 Plan, as applicable, as required by Rule 428(b)(1). In accordance with the rules and regulations of the Commission and the instructions to Form S-8, such documents are not being filed with the Commission either as part of this Post-Effective Amendment or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act. 

**PART II** 

**INFORMATION REQUIRED IN THE REGISTRATION STATEMENT** 

**ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.** 

The following documents filed by the Registrant with the Commission are incorporated by reference into this Post-Effective Amendment:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. The Registrant's [Annual Report on Form 10-K for its fiscal year ended December 31, 2025](http://www.sec.gov/Archives/edgar/data/203596/000119312526085463/wsbc-20251231.htm) , as filed on March 2, 2026 (File No. 001-39442);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. The Registrant's Current Reports on Form 8-K filed on [January 23, 2026](http://www.sec.gov/Archives/edgar/data/../../../ix?doc=/Archives/edgar/data/203596/000119312526020368/wsbc-20260122.htm) , [March 2, 2026](http://www.sec.gov/Archives/edgar/data/../../../ix?doc=/Archives/edgar/data/0000203596/000119312526085565/d115609d8k.htm) , [March 4, 2026](http://www.sec.gov/Archives/edgar/data/203596/000119312526091785/wsbc-20260304.htm) and [April 16, 2026](http://www.sec.gov/Archives/edgar/data/203596/000119312526159175/wsbc-20260415.htm) ;
and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. The description of the Registrant's securities contained in [Exhibit 4.1](http://www.sec.gov/Archives/edgar/data/203596/000119312526085463/wsbc-ex4_7.htm) of the Registrant's Annual Report on Form 10-K for its fiscal year ended December 31, 2025, filed with the Commission on March 
2, 2026, including any amendments or reports filed for the purpose of updating such description.

All documents subsequently filed by the Registrant with the Commission pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act after the date of this Post-Effective Amendment, but prior to the filing of a post-effective amendment to this Post-Effective Amendment that indicates that all securities offered by this Post-Effective Amendment have been sold or which deregisters all such securities then remaining unsold, shall be deemed to be incorporated by reference into this Post-Effective Amendment; provided, however, that the Registrant is not incorporating by reference any information furnished (but not filed) under Item 2.02 or Item 7.01 of any Current Report on Form 8-K or any exhibit furnished therein that relates to such items. Each document incorporated by reference into this Post-Effective Amendment shall be deemed to be a part of this Post-Effective

------

Amendment from the date of filing of such document with the Commission until the information contained therein is superseded or updated by any subsequently filed document that is incorporated by reference into this Post-Effective Amendment or by any document that constitutes part of the prospectus relating to the Prior Plan or the 2026 Plan, as applicable, each meeting the requirements of Section 10(a) of the Securities Act.

**ITEM 4. DESCRIPTION OF SECURITIES.** 

Not applicable.

**ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.** 

Denise Knouse-Snyder is a member of the law firm of Phillips, Gardill, Kaiser & Altmeyer, PLLC, whose legal opinion with respect to the securities registered hereunder is filed as Exhibit 5.1 hereto. Denise Knouse-Snyder also serves on the Board of Directors of the Registrant. As of April 15, 2026, the members of Phillips, Gardill, Kaiser & Altmeyer, PLLC owned an aggregate of approximately 46,344 shares of Common Stock.

**ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.** 

The Registrant's Bylaws provide, and West Virginia law permits, the indemnification of directors and officers against certain liabilities. Officers and directors of the Registrant and its subsidiaries are indemnified, to the maximum extent permitted under the West Virginia Business Corporation Act (including advanced indemnification payments), against liabilities incurred in connection with proceedings in which they are made parties by reason of their being or having been directors or officers of the corporation, except for certain prohibitions set forth in the Registrant's Bylaws regarding "prohibited indemnification payments." The Registrant does provide indemnity insurance to its officers and directors. Such insurance will not, however, indemnify officers or directors for willful misconduct or gross negligence in the performance of a duty to the Registrant.

I. Article VI of the Bylaws of Wesbanco provides:

***Indemnification of Directors and Officers***

SECTION 1. Indemnification . Each director and officer, whether or not then in office, shall be indemnified by the corporation against liability incurred by and imposed upon him in connection with or resulting from any action, suit or proceeding, to which he may be made a party by reason of his being or having been a director or officer of the corporation, or of any other company which he served at the request of the corporation, to the maximum extent permitted under the West Virginia Business Corporation Act, except as prohibited by Section 2 and Section 4 of this Article VI. The foregoing right of indemnification shall not be exclusive of other rights to which he may be entitled as a matter of law. Expenses incurred in defending a civil or criminal action, suit or proceeding may be paid by the corporation in advance of the final disposition of such action, suit or proceeding as authorized by the board of directors in accordance with the provisions of the West Virginia Business Corporation Act.

------

SECTION 2. Prohibited Indemnification Payment. Notwithstanding the provisions of Section 1 of this Article VI, no director or officer shall receive a "prohibited indemnification payment," which is any payment or agreement to make a payment to pay or reimburse such director or officer for any liability or legal expenses in any administrative proceeding brought by the appropriate federal banking agency that results in a final order or settlement in which the director or officer is assessed a civil money penalty, is removed or prohibited from conducting the business of banking, or is required to cease an action or take any affirmative action, including making restitution, with respect to Wesbanco Bank, Inc. or the corporation.

SECTION 3. Insurance. The corporation may purchase commercial insurance to cover certain costs that the corporation incurs under the indemnification provisions of Section 1 of this Article VI. Costs that may be covered include legal expenses and restitution that an individual may be ordered to make to the corporation. Such insurance may not, however, pay or reimburse a director or officer for any final judgment or civil money penalty assessed against such individual. Furthermore, partial indemnification for legal expenses is permitted in connection with a settlement when there is a formal and final finding that the director or officer has not breached a fiduciary duty, engaged in unsafe or unsound practices, and is not subject to a final prohibition order.

SECTION 4. Determination that Indemnification is Proper. The corporation may make or agree to make a reasonable indemnification payment if all of the following conditions are met: (i) the board of directors investigates and determines in writing that the director or officer acted in good faith and in the best interests of Wesbanco Bank, Inc.; (ii) the board of directors investigates and determines that the payment will not materially adversely affect the safety and soundness of Wesbanco Bank, Inc. or the corporation; (iii) the payment does not fall within the definition of a prohibited indemnification payment; and (iv) the director or officer agrees in writing to reimburse the corporation, to the extent not covered by permissible insurance, for advanced indemnification payments that subsequently become prohibited indemnification payments.

II. W. Va. Code Section 31D-8-851 through Section 31D-8-856 provides:

***Section 31D-8-851. Permissible Indemnification.***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) Except as otherwise provided in this section, a corporation may indemnify an individual who is a party to a proceeding because he or she is a director against liability incurred in the proceeding if:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) (A) He or she conducted himself or herself in good faith; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(B) He or she reasonably believed: (i) In the case of conduct in his or her official capacity, that his or her conduct was in the best interests of the corporation; and (ii) in all other cases, that his or her conduct was at least not opposed to the best interests of the corporation; and

------

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(C) In the case of any criminal proceeding, he or she had no reasonable cause to believe his or her conduct was unlawful; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) He or she engaged in conduct for which broader indemnification has been made permissible or obligatory under a provision of the articles of incorporation as authorized by subdivision (5), subsection (b), section two hundred two, article two of this chapter.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) A director's conduct with respect to an employee benefit plan for a purpose he or she reasonably believed to be in the interests of the participants in, and the beneficiaries of, the plan is conduct that satisfies the requirement of subparagraph (ii), paragraph (B), subdivision (1), subsection (a) of this section.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) The termination of a proceeding by judgment, order, settlement or conviction, or upon a plea of nolo contendere or its equivalent, is not determinative that the director did not meet the relevant standard of conduct described in this section.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) Unless ordered by a court under subdivision (3), subsection (a), section eight hundred fifty-four of this article, a corporation may not indemnify a director:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) In connection with a proceeding by or in the right of the corporation, except for reasonable expenses incurred in connection with the proceeding if it is determined that the director has met the relevant standard of conduct under subsection (a) of this section; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) In connection with any proceeding with respect to conduct for which he or she was adjudged liable on the basis that he or she received a financial benefit to which he or she was not entitled, whether or not involving action in his or her official capacity.

***Section 31D-8-852. Mandatory Indemnification.***

A corporation must indemnify a director who was wholly successful, on the merits or otherwise, in the defense of any proceeding to which he or she was a party because he or she was a director of the corporation against reasonable expenses incurred by him or her in connection with the proceeding.

***Section 31D-8-853. Advance for Expenses.***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) A corporation may, before final disposition of a proceeding, advance funds to pay for or reimburse the reasonable expenses incurred by a director who is a party to a proceeding because he or she is a director if he or she delivers to the corporation:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) A written affirmation of his or her good faith belief that he or she has met the relevant standard of conduct described in section eight hundred fifty-one of this article or that the proceeding involves conduct for which liability has been eliminated under a provision of the articles of incorporation as authorized by subdivision (4), subsection (b), section two hundred two, article two of this chapter; and

------

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) His or her written undertaking to repay any funds advanced if he or she is not entitled to mandatory indemnification under section eight hundred fifty-two of this article and it is ultimately determined under section eight hundred fifty-four or eight hundred fifty-five of this article that he or she has not met the relevant standard of conduct described in section eight hundred fifty-one of this article.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The undertaking required by subdivision (2), subsection (a) of this section must be an unlimited general obligation of the director but need not be secured and may be accepted without reference to the financial ability of the director to make repayment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) Authorizations under this section are to be made:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) By the board of directors:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(A) If there are two or more disinterested directors, by a majority vote of all the disinterested directors, a majority of whom constitute a quorum for this purpose, or by a majority of the members of a committee of two or more disinterested directors appointed by a vote; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(B) If there are fewer than two disinterested directors, by the vote necessary for action by the board in accordance with subsection (c), section eight hundred twenty-four of this article in which authorization directors who do not qualify as disinterested directors may participate; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) By the shareholders, but shares owned by or voted under the control of a director who at the time does not qualify as a disinterested director may not be voted on the authorization; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) By special legal counsel selected in a manner in accordance with subdivision (2), subsection (b), section eight hundred fifty-five of this article.

***Section 31D-8-854. Circuit Court-Ordered Indemnification and Advance for Expenses.***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) A director who is a party to a proceeding because he or she is a director may apply for indemnification or an advance for expenses to the circuit court conducting the proceeding or to another circuit court of competent jurisdiction. After receipt of an application and after giving any notice it considers necessary, the circuit court shall:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) Order indemnification if the circuit court determines that the director is entitled to mandatory indemnification under section eight hundred fifty-two of this article;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) Order indemnification or advance for expenses if the circuit court determines that the director is entitled to indemnification or advance for expenses pursuant to a provision authorized by subsection (a), section eight hundred fifty-eight of this article; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) Order indemnification or advance for expenses if the circuit court determines, in view of all the relevant circumstances, that it is fair and reasonable:

------

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(A) To indemnify the director; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(B) To advance expenses to the director, even if he or she has not met the relevant standard of conduct set forth in subsection (a), section eight hundred fifty-one of this article, failed to comply with section eight hundred fifty-three of this article or was adjudged liable in a proceeding referred to in subdivision (1) or (2), subsection (d), section eight hundred fifty-one of this article, but if he or she was adjudged so liable his or her indemnification is to be limited to reasonable expenses incurred in connection with the proceeding.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) If the circuit court determines that the director is entitled to indemnification under subdivision (1), subsection (a) of this section or to indemnification or advance for expenses under subdivision (2) of said subsection, it shall also order the corporation to pay the director's reasonable expenses incurred in connection with obtaining circuit court-ordered indemnification or advance for expenses. If the circuit court determines that the director is entitled to indemnification or advance for expenses under subdivision (3) of said subsection, it may also order the corporation to pay the director's reasonable expenses to obtain circuit court-ordered indemnification or advance for expenses.

***Section 31D-8-855. Determination and Authorization of Indemnification.***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) A corporation may not indemnify a director under section eight hundred fifty-one of this article unless authorized for a specific proceeding after a determination has been made that indemnification of the director is permissible because he or she has met the relevant standard of conduct set forth in section eight hundred fifty-one of this article.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The determination is to be made:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) If there are two or more disinterested directors, by the board of directors by a majority vote of all the disinterested directors, a majority of whom constitute a quorum for this purpose, or by a majority of the members of a committee of two or more disinterested directors appointed by a vote;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) By special legal counsel:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(A) Selected in the manner prescribed in subdivision (1) of this subsection; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(B) If there are fewer than two disinterested directors, selected by the board of directors in which selection directors who do not qualify as disinterested directors may participate; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) By the shareholders, but shares owned by or voted under the control of a director who at the time does not qualify as a disinterested director may not be voted on the determination.

------

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) Authorization of indemnification is to be made in the same manner as the determination that indemnification is permissible, except that if there are fewer than two disinterested directors or if the determination is made by special legal counsel, authorization of indemnification is to be made by those entitled under paragraph (B), subdivision (2), subsection (b) of this section to select special legal counsel.

***Section 31D-8-856. Indemnification of Officers.***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) A corporation may indemnify and advance expenses under this part to an officer of the corporation who is a party to a proceeding because he or she is an officer of the corporation:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) To the same extent as a director; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) If he or she is an officer but not a director, to a further extent as may be provided by the articles of incorporation, the bylaws, a resolution of the board of directors or contract except for:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(A) Liability in connection with a proceeding by or in the right of the corporation other than for reasonable expenses incurred in connection with the proceeding; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(B) Liability arising out of conduct that constitutes:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) Receipt by him or her of a financial benefit to which he or she is not entitled;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii) An intentional infliction of harm on the corporation or the shareholders; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii) An intentional violation of criminal law.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The provisions of subdivision (2), subsection (a) of this section apply to an officer who is also a director if the basis on which he or she is made a party to the proceeding is an act or omission solely as an officer.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) An officer of a corporation who is not a director is entitled to mandatory indemnification under section eight hundred fifty-two of this article and may apply to a court under section eight hundred fifty-four of this article for indemnification or an advance for expenses in each case to the same extent to which a director may be entitled to indemnification or advance for expenses under those provisions.

Certain rules of the Federal Deposit Insurance Corporation limit the ability of certain depository institutions, their subsidiaries and their affiliated depository institution holding companies to indemnify affiliated parties, including institution directors. In general, subject to the ability to purchase directors' and officers' liability insurance and to advance professional expenses under certain circumstances, the rules prohibit such institutions from indemnifying a director for certain costs incurred with regard to an administrative or enforcement action commenced by any federal banking agency that results in a final order or settlement pursuant to which the director is assessed a civil money penalty, removed from office, prohibited from participating in the affairs of an insured depository institution or required to cease and desist from or take an affirmative action described in Section 8(b) of the Federal Deposit Insurance Act (12 U.S.C. § 1818(b)).

------

**ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.** 

Not Applicable.

**ITEM 8. EXHIBITS.** 

---

| | |
|:---|:---|
| **Exhibit No.** | **Description** |
| 4.1 | [Restated Articles of Incorporation of Wesbanco, Inc. (incorporated by reference to Exhibit 3.2 of the Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2019, filed with the Securities and Exchange Commission on February 28, 2020).](http://www.sec.gov/Archives/edgar/data/203596/000156459020007827/wsbc-ex32_693.htm) |
| 4.2 | [Articles of Amendment to the Restated Articles of Incorporation of Wesbanco, Inc. (incorporated by reference to Exhibit 3.1 of the Registrant's Current Report on Form 8-K, filed with the Securities and Exchange Commission on August 11, 2020).](http://www.sec.gov/Archives/edgar/data/203596/000119312520216296/d76551dex31.htm) |
| 4.3 | [Articles of Amendment to the Restated Articles of Incorporation of Wesbanco, Inc. (Incorporated by reference to Exhibit 3.1 of the Registrant's Current Report on Form 8-K, filed with the Securities and Exchange Commission on December 11, 2024).](http://www.sec.gov/Archives/edgar/data/203596/000095017024135445/wsbc-ex3_1.htm) |
| 4.4 | [Articles of Amendment to the Restated Articles of Incorporation of Wesbanco, Inc. (Incorporated by reference t Exhibit 3.1 of the Registrant's Current Report on Form 8-K, filed with the Securities and Exchange Commission on September 17, 2025).](http://www.sec.gov/Archives/edgar/data/203596/000119312525206133/d862034dex31.htm) |
| 4.5 | [Articles of Amendment to the Restated Articles of Incorporation of Wesbanco, Inc. (Incorporated by reference to Exhibit 3.6 of the Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2025, filed with the Securities and Exchange Commission on March 2, 2026).](http://www.sec.gov/Archives/edgar/data/203596/000119312526085463/wsbc-ex3_6.htm) |
| 4.6 | [Bylaws of Wesbanco, Inc. (As Amended and Restated May 4, 2021) (incorporated by reference to Exhibit 3.1 of the Registrant's Quarterly Report on Form 10-Q for the fiscal quarter ended March 31, 2021, filed with the Securities and Exchange Commission on May 6, 2021).](http://www.sec.gov/Archives/edgar/data/203596/000156459021024985/wsbc-ex31_81.htm) |
| 4.7 | [Wesbanco, Inc. Incentive Bonus, Option and Restricted Stock Plan, as amended and restated (incorporated by reference to Exhibit 10.1 of the Registrant's Current Report on Form 8-K, filed with the Securities and Exchange Commission on April 18, 2024).](http://www.sec.gov/Archives/edgar/data/203596/000095017024045577/wsbc-ex10_1.htm) |

---

------

---

| | |
|:---|:---|
| 4.8 | [Wesbanco, Inc. 2026 Equity Incentive Plan (incorporated by reference to Exhibit 10.1 of the Registrant's Current Report on Form 8-K, filed with the Securities and Exchange Commission on April 16, 2026).](http://www.sec.gov/Archives/edgar/data/203596/000119312526159175/wsbc-ex10_1.htm) |
|  4.9\* | Form of Common Stock Certificate (incorporated by reference to the Registration Statement filed by the Registrant on Form S-4 (Registration No. 33-42157), filed with the Securities and Exchange Commission on August 9, 1991). |
| 4.10 | [Wesbanco, Inc. Description of Securities (incorporated by reference to Exhibit 4.7 to the Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2025, filed with the Securities and Exchange Commission on March 2, 2026).](http://www.sec.gov/Archives/edgar/data/203596/000119312526085463/wsbc-ex4_7.htm) |
| 5.1 | [Opinion of Phillips, Gardill, Kaiser & Altmeyer, PLLC, regarding the legality of the shares being registered hereunder (filed herewith).](d108318dex51.htm) |
| 23.1 | [Consent of Ernst & Young LLP, Independent Registered Public Accounting Firm (filed herewith).](d108318dex231.htm) |
| 23.2 | [Consent of Crowe LLP (filed herewith)](d108318dex232.htm) |
| 23.3 | [Consent of Phillips, Gardill, Kaiser & Altmeyer, PLLC (included in Exhibit 5.1).](d108318dex51.htm) |
| 24.1 | [Power of Attorney (set forth on the signature page of this Post-Effective Amendment).](#sig) |
| 99.1 | [Audited consolidated financial statements of Premier Financial Corp. as of December 31, 2024 and 2023 and for each of the three years ended December 31, 2024, as well as the accompanying notes thereto and the related Report of the Independent Registered Public Accounting Firm (incorporated by reference to the Annual Report on Form 10-K filed by Premier Financial Corp. on February 28, 2025 (File No. 000-26850)).](http://www.sec.gov/Archives/edgar/data/946647/000095017025029956/pfc-20241231.htm) |
| 99.2 | [Unaudited pro forma condensed combined statement of income for the year ended December 31, 2025 (incorporated by reference to Exhibit 99.1 of the Registrant's Current Report on Form 8-K, filed with the Securities and Exchange Commission on March 2, 2026).](http://www.sec.gov/Archives/edgar/data/203596/000119312526085565/d115609dex991.htm) |

---

\* This exhibit has been paper filed and is not subject to the hyperlinking requirements of Item 601 of Regulation S-K.

------

**ITEM 9. UNDERTAKINGS.** 

(a) The undersigned Registrant hereby undertakes:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;i. To include any prospectus required by Section 10(a)(3) of the Securities Act;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;ii. To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than 20% change in the maximum aggregate offering price set forth in the "Calculation of Filing Fee Tables" or "Calculation of Registration Fee" table, as applicable, in the effective Registration Statement.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;iii. To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in this Registration Statement;

provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) of this section do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in this Registration Statement.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.

(b) The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

------

(c) Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

------

**SIGNATURES** 

Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Post-Effective Amendment to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Wheeling, State of West Virginia, on April 23, 2026.

---

| | |
|:---|:---|
| WESBANCO, INC. | WESBANCO, INC. |
| By: | /s/ Jeffrey H. Jackson |
|  | Jeffrey H. Jackson |
|  | President and Chief Executive Officer |

---

POWER OF ATTORNEY

KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Jeffrey H. Jackson, Daniel K. Weiss, Jr. and Richard Laws, and each of them, his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments to this Registration Statement, and to file the same, with all exhibits thereto, and other documentation in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents with full power and authority to do and perform each and every act and thing requisite and necessary to be done in or about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or their substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this Post-Effective Amendment has been signed by the following persons in the capacities indicated on April 23, 2026.

---

| | |
|:---|:---|
| **Signature** | **Title** |
| /s/ Jeffrey H. Jackson | President, Chief Executive Officer & Director |
| Jeffrey H. Jackson | (Principal Executive Officer) |
| /s/ Daniel K. Weiss, Jr. | Senior Executive Vice President & |
| Daniel K. Weiss, Jr. | Chief Financial Officer |
|  | (Principal Financial and Accounting Officer) |

---

------

---

| | |
|:---|:---|
| /s/ Christopher V. Criss | Chairman of the Board |
| Christopher V. Criss |  |
| /s/ Zahid Afzal | Director |
| Zahid Afzal |  |
| /s/ Rosie Allen-Herring | Director |
| Rosie Allen-Herring |  |
| /s/ Louis M. Altman | Director |
| Louis M. Altman |  |
| /s/ John L. Bookmyer | Director |
| John L. Bookmyer |  |
| /s/ Lee J. Burdman | Director |
| Lee J. Burdman |  |
| /s/ Todd F. Clossin | Director |
| Todd F. Clossin |  |
| /s/ Robert J. Fitzsimmons | Director |
| Robert J. Fitzsimmons |  |
| /s/ Denise Knouse-Snyder | Director |
| Denise Knouse-Snyder |  |
| /s/ Lisa A. Knutson | Director |
| Lisa A. Knutson |  |
| /s/ F. Eric Nelson, Jr. | Director |
| F. Eric Nelson, Jr. |  |
| /s/ Gregory S. Proctor, Jr. | Director |
| Gregory S. Proctor, Jr. |  |
| /s/ Joseph R. Robinson | Director |
| Joseph R. Robinson |  |
| /s/ Kerry M. Stemler | Director |
| Kerry M. Stemler |  |

---

## Exhibit 5.1

**Exhibit 5.1** 

[Letterhead of Phillips, Gardill, Kaiser & Altmeyer, PLLC]

April 23 2026

Wesbanco, Inc.

One Bank Plaza

Wheeling, WV 26003

Ladies and Gentlemen:

We have acted as counsel for Wesbanco, Inc. (the "Company") in connection with the preparation of the Post-Effective Amendment No. 1 (the "Post-Effective Amendment") to the Registration Statement on Form S-8 (File No. 333-255443) to be filed by the Company with the Securities and Exchange Commission (the "Commission") for the registration under the Securities Act of 1933, as amended (the "Securities Act"), of the offering and sale of up to 3,086,080 shares of the Company's common stock, par value $2.0833 per share (the "Shares"), which may be offered from time to time pursuant to the Wesbanco, Inc. 2026 Equity Incentive Plan (the "Plan").

We have examined the originals, certified copies or copies otherwise identified to my satisfaction as being true copies of the Plan and such other documents as we have deemed necessary or appropriate for purposes of this opinion.

Based on the foregoing, we are of the opinion that the Shares have been duly and validly authorized and reserved for issuance, and that the Shares, when issued under the terms of the Plan (assuming in each case that the individual issuances, grants or awards under the Plan are duly authorized by all necessary corporate action and duly issued, granted or awarded and exercised in accordance with the requirements of law and the Plan), and when the Registration Statement has become effective under the Securities Act, will be validly issued, fully paid and nonassessable.

This opinion is for your benefit in connection with the Registration Statement and may be relied upon by you and by persons entitled to rely upon it pursuant to the applicable provisions of the Securities Act. We consent to your filing this opinion as an exhibit to the Registration Statement. In giving such consent, we do not thereby admit that we are in the category of persons whose consent is required under Section 7 of the Act or the rules and regulations of the Commission thereunder.

---

| |
|:---|
| Very truly yours, |
| PHILLIPS, GARDILL, KAISER & ALTMEYER, PLLC |
| /s/ James C. Gardill |
| James C. Gardill |

---

## Exhibit 23.1

**Exhibit 23.1** 

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in Post-effective Amendment No. 1 to the following Registration Statements pertaining to Wesbanco, Inc.'s Incentive, Bonus, Option and Restricted Stock Plan:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration Statement (Form S-8 No. 333-107736),

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration Statement (Form S-8 No. 333-166541),

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration Statement (Form S-8 No. 333-217398),

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration Statement (Form S-8 No. 333-255443),

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Registration Statement (Form S-8 No. 333-278833);

of our reports dated March 2, 2026, with respect to the consolidated financial statements of Wesbanco, Inc. and the effectiveness of internal control over financial reporting of Wesbanco, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2025, filed with the Securities and Exchange Commission.

/s/ Ernst & Young LLP

Pittsburgh, Pennsylvania

April 23, 2026

## Exhibit 23.2

**Exhibit 23.2** 

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in this Post-Effective Amendment No.1 to the Registration Statement on Form S-8 of Wesbanco, Inc. of our report dated February 28, 2025, relating to the consolidated statements of financial condition of Premier Financial Corp. as of December 31, 2024 and 2023, the related consolidated statements of income, comprehensive income, changes in stockholders' equity, and cash flows for each of the years in the three-year period ended December 31, 2024, which is incorporated by reference in Exhibit 99.1 of this Post-Effective Amendment No. 1 to the Registration Statement on Form S-8.

/s/ Crowe LLP

Crowe LLP

Cleveland, Ohio

April 23, 2026