# EDGAR Filing Document

**Accession Number:** 0000729528
**File Stem:** 0000051931-23-000324
**Filing Date:** 2023-3
**Character Count:** 80723
**Document Hash:** d5dbbabd00e2b235272025acef3c7db0
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000051931-23-000324.hdr.sgml**: 20230327

**ACCESSION NUMBER**: 0000051931-23-000324

**CONFORMED SUBMISSION TYPE**: 24F-2NT

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230327

**DATE AS OF CHANGE**: 20230327

**EFFECTIVENESS DATE**: 20230327

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** AMERICAN FUNDS INSURANCE SERIES
- **CENTRAL INDEX KEY:** 0000729528
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** MA
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 24F-2NT
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 002-86838
- **FILM NUMBER:** 23762286

**BUSINESS ADDRESS:**
- **STREET 1:** 333 S HOPE ST - 55TH FL (MICG)
- **CITY:** LOS ANGELES
- **STATE:** CA
- **ZIP:** 90071
- **BUSINESS PHONE:** 213-486-9200

**MAIL ADDRESS:**
- **STREET 1:** 333 S HOPE ST - 55TH FL (MICG)
- **CITY:** LOS ANGELES
- **STATE:** CA
- **ZIP:** 90071

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMERICAN FUND INSURANCE SERIES
- **DATE OF NAME CHANGE:** 20010829

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMERICAN VARIABLE INSURANCE SERIES
- **DATE OF NAME CHANGE:** 19920703

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMERICAN PATHWAY FUND
- **DATE OF NAME CHANGE:** 19880531

## Series and Classes Contracts Data

### Global Growth Fund (Series ID: S000008786)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023903 |
| Class 2    | C000023904 |
| Class 4    | C000121502 |
| Class 1A   | C000176234 |

---

### American High-Income Trust (Series ID: S000008787)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023905 |
| Class 2    | C000023906 |
| Class 3    | C000023907 |
| Class 4    | C000121503 |
| Class 1A   | C000176235 |

---

### U.S. Government Securities Fund (Series ID: S000008788)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023908 |
| Class 2    | C000023909 |
| Class 3    | C000023910 |
| Class 4    | C000121504 |
| Class 1A   | C000176236 |

---

### Ultra-Short Bond Fund (Series ID: S000008789)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023911 |
| Class 2    | C000023912 |
| Class 3    | C000023913 |
| Class 4    | C000121505 |
| Class 1A   | C000176237 |

---

### Global Small Capitalization Fund (Series ID: S000008790)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023914 |
| Class 2    | C000023915 |
| Class 4    | C000121506 |
| Class 1A   | C000176238 |

---

### Growth Fund (Series ID: S000008791)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023916 |
| Class 2    | C000023917 |
| Class 3    | C000023918 |
| Class 4    | C000121507 |
| Class 1A   | C000176239 |

---

### International Fund (Series ID: S000008792)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023919 |
| Class 2    | C000023920 |
| Class 3    | C000023921 |
| Class 4    | C000121508 |
| Class 1A   | C000176240 |

---

### New World Fund (Series ID: S000008793)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023922 |
| Class 2    | C000023923 |
| Class 4    | C000121509 |
| Class 1A   | C000176241 |

---

### Washington Mutual Investors Fund (Series ID: S000008794)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023924 |
| Class 2    | C000023925 |
| Class 4    | C000121510 |
| Class 1A   | C000176242 |

---

### Growth-Income Fund (Series ID: S000008795)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023926 |
| Class 2    | C000023927 |
| Class 3    | C000023928 |
| Class 4    | C000121511 |
| Class 1A   | C000176243 |

---

### Asset Allocation Fund (Series ID: S000008796)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023929 |
| Class 2    | C000023930 |
| Class 3    | C000023931 |
| Class 4    | C000121512 |
| Class 1A   | C000176244 |

---

### The Bond Fund of America (Series ID: S000008797)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023932 |
| Class 2    | C000023933 |
| Class 4    | C000121513 |
| Class 1A   | C000176245 |

---

### Capital World Growth and Income Fund (Series ID: S000013710)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000037623 |
| Class 2    | C000037624 |
| Class 4    | C000121514 |
| Class 1A   | C000176246 |

---

### Capital World Bond Fund (Series ID: S000013796)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000037827 |
| Class 2    | C000037828 |
| Class 4    | C000121515 |
| Class 1A   | C000176247 |

---

### International Growth and Income Fund (Series ID: S000023461)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000068980 |
| Class 2    | C000068981 |
| Class 4    | C000121516 |
| Class 1A   | C000176248 |

---

### American Funds Global Balanced Fund (Series ID: S000031859)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000099201 |
| Class 2    | C000099202 |
| Class 4    | C000121517 |
| Class 1A   | C000176249 |

---

### American Funds Mortgage Fund (Series ID: S000031860)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000099203 |
| Class 2    | C000099204 |
| Class 4    | C000121518 |
| Class 1A   | C000176250 |

---

### Managed Risk Asset Allocation Fund (Series ID: S000038240)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000117906 |
| Class P2   | C000117907 |

---

### Managed Risk Growth Fund (Series ID: S000040665)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126054 |
| Class P2   | C000126055 |

---

### Managed Risk International Fund (Series ID: S000040666)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126056 |
| Class P2   | C000126057 |

---

### Managed Risk Washington Mutual Investors Fund (Series ID: S000040667)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126058 |
| Class P2   | C000126059 |

---

### Managed Risk Growth-Income Fund (Series ID: S000040668)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126060 |
| Class P2   | C000126061 |

---

### Capital Income Builder (Series ID: S000045163)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000140604 |
| Class 2    | C000140605 |
| Class 4    | C000140606 |
| Class 1A   | C000176252 |

---

### Portfolio Series - American Funds Global Growth Portfolio (Series ID: S000048970)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000154330 |
| Class 2    | C000154331 |
| Class 4    | C000154332 |
| Class 1A   | C000176253 |

---

### Portfolio Series - American Funds Growth and Income Portfolio (Series ID: S000048971)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000154333 |
| Class 2    | C000154334 |
| Class 4    | C000154335 |
| Class 1A   | C000176254 |

---

### Portfolio Series - American Funds Managed Risk Global Allocation Portfolio (Series ID: S000048972)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000154336 |
| Class P2   | C000154337 |

---

### Portfolio Series - American Funds Managed Risk Growth Portfolio (Series ID: S000048973)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P2   | C000154338 |
| Class P1   | C000154339 |

---

### Portfolio Series - American Funds Managed Risk Growth and Income Portfolio (Series ID: S000048974)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000154340 |
| Class P2   | C000154341 |

---

### American Funds IS 2010 Target Date Fund (Series ID: S000067189)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000216157 |
| Class 1    | C000216158 |
| Class 2    | C000216159 |
| Class 4    | C000216160 |

---

### American Funds IS 2015 Target Date Fund (Series ID: S000067190)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000216161 |
| Class 1A   | C000216162 |
| Class 1    | C000216163 |
| Class 2    | C000216164 |

---

### American Funds IS 2020 Target Date Fund (Series ID: S000067191)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000216165 |
| Class 2    | C000216166 |
| Class 1A   | C000216167 |
| Class 1    | C000216168 |

---

### American Funds IS 2025 Target Date Fund (Series ID: S000067192)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000216169 |
| Class 2    | C000216170 |
| Class 4    | C000216171 |
| Class 1    | C000216172 |

---

### American Funds IS 2030 Target Date Fund (Series ID: S000067193)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000216173 |
| Class 2    | C000216174 |
| Class 4    | C000216175 |
| Class 1    | C000216176 |

---

### American Funds IS 2035 Target Date Fund (Series ID: S000067194)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000216177 |
| Class 1A   | C000216178 |
| Class 2    | C000216179 |
| Class 4    | C000216180 |

---

## Series and Classes Contracts Data

### Global Growth Fund (Series ID: S000008786)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023903 | Class 1      |  |
| C000023904 | Class 2      |  |
| C000121502 | Class 4      |  |
| C000176234 | Class 1A     |  |

### American High-Income Trust (Series ID: S000008787)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023905 | Class 1      |  |
| C000023906 | Class 2      |  |
| C000023907 | Class 3      |  |
| C000121503 | Class 4      |  |
| C000176235 | Class 1A     |  |

### U.S. Government Securities Fund (Series ID: S000008788)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023908 | Class 1      |  |
| C000023909 | Class 2      |  |
| C000023910 | Class 3      |  |
| C000121504 | Class 4      |  |
| C000176236 | Class 1A     |  |

### Ultra-Short Bond Fund (Series ID: S000008789)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023911 | Class 1      |  |
| C000023912 | Class 2      |  |
| C000023913 | Class 3      |  |
| C000121505 | Class 4      |  |
| C000176237 | Class 1A     |  |

### Global Small Capitalization Fund (Series ID: S000008790)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023914 | Class 1      |  |
| C000023915 | Class 2      |  |
| C000121506 | Class 4      |  |
| C000176238 | Class 1A     |  |

### Growth Fund (Series ID: S000008791)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023916 | Class 1      |  |
| C000023917 | Class 2      |  |
| C000023918 | Class 3      |  |
| C000121507 | Class 4      |  |
| C000176239 | Class 1A     |  |

### International Fund (Series ID: S000008792)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023919 | Class 1      |  |
| C000023920 | Class 2      |  |
| C000023921 | Class 3      |  |
| C000121508 | Class 4      |  |
| C000176240 | Class 1A     |  |

### New World Fund (Series ID: S000008793)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023922 | Class 1      |  |
| C000023923 | Class 2      |  |
| C000121509 | Class 4      |  |
| C000176241 | Class 1A     |  |

### Washington Mutual Investors Fund (Series ID: S000008794)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023924 | Class 1      |  |
| C000023925 | Class 2      |  |
| C000121510 | Class 4      |  |
| C000176242 | Class 1A     |  |

### Growth-Income Fund (Series ID: S000008795)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023926 | Class 1      |  |
| C000023927 | Class 2      |  |
| C000023928 | Class 3      |  |
| C000121511 | Class 4      |  |
| C000176243 | Class 1A     |  |

### Asset Allocation Fund (Series ID: S000008796)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023929 | Class 1      |  |
| C000023930 | Class 2      |  |
| C000023931 | Class 3      |  |
| C000121512 | Class 4      |  |
| C000176244 | Class 1A     |  |

### The Bond Fund of America (Series ID: S000008797)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023932 | Class 1      |  |
| C000023933 | Class 2      |  |
| C000121513 | Class 4      |  |
| C000176245 | Class 1A     |  |

### Capital World Growth and Income Fund (Series ID: S000013710)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000037623 | Class 1      |  |
| C000037624 | Class 2      |  |
| C000121514 | Class 4      |  |
| C000176246 | Class 1A     |  |

### Capital World Bond Fund (Series ID: S000013796)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000037827 | Class 1      |  |
| C000037828 | Class 2      |  |
| C000121515 | Class 4      |  |
| C000176247 | Class 1A     |  |

### International Growth and Income Fund (Series ID: S000023461)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000068980 | Class 1      |  |
| C000068981 | Class 2      |  |
| C000121516 | Class 4      |  |
| C000176248 | Class 1A     |  |

### American Funds Global Balanced Fund (Series ID: S000031859)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000099201 | Class 1      |  |
| C000099202 | Class 2      |  |
| C000121517 | Class 4      |  |
| C000176249 | Class 1A     |  |

### American Funds Mortgage Fund (Series ID: S000031860)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000099203 | Class 1      |  |
| C000099204 | Class 2      |  |
| C000121518 | Class 4      |  |
| C000176250 | Class 1A     |  |

### Managed Risk Asset Allocation Fund (Series ID: S000038240)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000117906 | Class P1     |  |
| C000117907 | Class P2     |  |

### Managed Risk Growth Fund (Series ID: S000040665)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126054 | Class P1     |  |
| C000126055 | Class P2     |  |

### Managed Risk International Fund (Series ID: S000040666)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126056 | Class P1     |  |
| C000126057 | Class P2     |  |

### Managed Risk Washington Mutual Investors Fund (Series ID: S000040667)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126058 | Class P1     |  |
| C000126059 | Class P2     |  |

### Managed Risk Growth-Income Fund (Series ID: S000040668)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126060 | Class P1     |  |
| C000126061 | Class P2     |  |

### Capital Income Builder (Series ID: S000045163)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000140604 | Class 1      |  |
| C000140605 | Class 2      |  |
| C000140606 | Class 4      |  |
| C000176252 | Class 1A     |  |

### Portfolio Series - American Funds Global Growth Portfolio (Series ID: S000048970)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154330 | Class 1      |  |
| C000154331 | Class 2      |  |
| C000154332 | Class 4      |  |
| C000176253 | Class 1A     |  |

### Portfolio Series - American Funds Growth and Income Portfolio (Series ID: S000048971)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154333 | Class 1      |  |
| C000154334 | Class 2      |  |
| C000154335 | Class 4      |  |
| C000176254 | Class 1A     |  |

### Portfolio Series - American Funds Managed Risk Global Allocation Portfolio (Series ID: S000048972)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154336 | Class P1     |  |
| C000154337 | Class P2     |  |

### Portfolio Series - American Funds Managed Risk Growth Portfolio (Series ID: S000048973)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154338 | Class P2     |  |
| C000154339 | Class P1     |  |

### Portfolio Series - American Funds Managed Risk Growth and Income Portfolio (Series ID: S000048974)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154340 | Class P1     |  |
| C000154341 | Class P2     |  |

### American Funds IS 2010 Target Date Fund (Series ID: S000067189)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216157 | Class 1A     |  |
| C000216158 | Class 1      |  |
| C000216159 | Class 2      |  |
| C000216160 | Class 4      |  |

### American Funds IS 2015 Target Date Fund (Series ID: S000067190)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216161 | Class 4      |  |
| C000216162 | Class 1A     |  |
| C000216163 | Class 1      |  |
| C000216164 | Class 2      |  |

### American Funds IS 2020 Target Date Fund (Series ID: S000067191)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216165 | Class 4      |  |
| C000216166 | Class 2      |  |
| C000216167 | Class 1A     |  |
| C000216168 | Class 1      |  |

### American Funds IS 2025 Target Date Fund (Series ID: S000067192)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216169 | Class 1A     |  |
| C000216170 | Class 2      |  |
| C000216171 | Class 4      |  |
| C000216172 | Class 1      |  |

### American Funds IS 2030 Target Date Fund (Series ID: S000067193)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216173 | Class 1A     |  |
| C000216174 | Class 2      |  |
| C000216175 | Class 4      |  |
| C000216176 | Class 1      |  |

### American Funds IS 2035 Target Date Fund (Series ID: S000067194)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216177 | Class 1      |  |
| C000216178 | Class 1A     |  |
| C000216179 | Class 2      |  |
| C000216180 | Class 4      |  |

## FORM 24F-2NT: Annual Notice of Securities Sold Pursuant to Rule 24f-2

### 24F-2NT: Filer Information

**Filer CIK:** 0000729528

**Is this a LIVE or TEST Filing?:** LIVE

**Filer Investment Company Type:** N-1A

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $6285367000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $5481210000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $5878011000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $11359221000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-5073854000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $8793808000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $4943412000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $10106147000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $15049559000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-6255751000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $169925000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $229736000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $892886000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1122622000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-952697000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $239004000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $142053000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $436966000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $579019000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-340015000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $244158000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $646430000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1502040000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2148470000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1904312000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $17124000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $248615000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $8090000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $256705000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-239581000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $188959000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $56200000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1315067000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1371267000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1182308000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $179278000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $283783000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1751791000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2035574000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1856296000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $54222000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $84884000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $6623000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $91507000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-37285000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $129685000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $32664000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $12892000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $45556000.00

- **(v) Net sales:** $84129000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $9271.02

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $9271.02

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $5018015000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $3619486000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $2298267000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $5917753000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-899738000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1684307000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1419098000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $3205979000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $4625077000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-2940770000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $3043068000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1712002000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $730757000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2442759000.00

- **(v) Net sales:** $600309000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $66154.05

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $66154.05

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $778939000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $603563000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1222357000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1825920000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1046981000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1445867000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $723872000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1737980000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2461852000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1015985000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $655790000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $732812000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $120872000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $853684000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-197894000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1520770000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $923135000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1120248000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2043383000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-522613000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1901948000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $2861098000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2861098000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-959150000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $134144000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $364242000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $487211000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $851453000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-717309000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $162900000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $186780000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $64385000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $251165000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-88265000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $10256000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $16269000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $2581000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $18850000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-8594000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $38358000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $39860000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $35114000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $74974000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-36616000.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $308464000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $199063000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $81691000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $280754000.00

- **(v) Net sales:** $27710000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $3053.64

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $3053.64

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $16390000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $8272000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $8272000.00

- **(v) Net sales:** $8118000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $894.60

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $894.60

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $68177000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $24700000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $24700000.00

- **(v) Net sales:** $43477000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $4791.17

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $4791.17

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $325861000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $77685000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $77685000.00

- **(v) Net sales:** $248176000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $27349.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $27349.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $160718000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $81703000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $81703000.00

- **(v) Net sales:** $79015000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $8707.45

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $8707.45

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $52712000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $33794000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1182000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $34976000.00

- **(v) Net sales:** $17736000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $1954.51

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $1954.51

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $176607000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $12728000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $12728000.00

- **(v) Net sales:** $163879000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $18059.47

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $18059.47

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $10567000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1133000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1133000.00

- **(v) Net sales:** $9434000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $1039.63

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $1039.63

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $189000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $124000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $124000.00

- **(v) Net sales:** $65000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $7.16

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $7.16

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $517000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $66000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $66000.00

- **(v) Net sales:** $451000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $49.70

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $49.70

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $329000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $40000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $40000.00

- **(v) Net sales:** $289000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $31.85

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $31.85

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $966000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $231000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $231000.00

- **(v) Net sales:** $735000.00

- **(vi) Redemption credits available for use in future years:** $-0.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $81.00

- **6(i). Amount of securities deducted:** $0.00

- **6(ii). Number of shares or other units remaining unsold:** 0.00

- **7. Interest due -- if this Form is being filed more than 90 days after the end of the issuer's fiscal year:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $81.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Greg Niland, Treasurer

**Date:** 03/27/2023

**Signature:** Greg Niland