# EDGAR Filing Document

**Accession Number:** 0001661181
**File Stem:** 0001661181-26-000007
**Filing Date:** 2026-5
**Character Count:** 32173
**Document Hash:** 157bda659009c43e1995328bb3b2fa69
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001661181-26-000007.hdr.sgml**: 20260507

**ACCESSION NUMBER**: 0001661181-26-000007

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 11

**CONFORMED PERIOD OF REPORT**: 20260507

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20260507

**DATE AS OF CHANGE**: 20260507

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Organogenesis Holdings Inc.
- **CENTRAL INDEX KEY:** 0001661181
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-37906
- **FILM NUMBER:** 26953384

**BUSINESS ADDRESS:**
- **STREET 1:** 85 DAN ROAD
- **CITY:** CANTON
- **STATE:** MA
- **ZIP:** 02021
- **BUSINESS PHONE:** 781-575-0775

**MAIL ADDRESS:**
- **STREET 1:** 85 DAN ROAD
- **CITY:** CANTON
- **STATE:** MA
- **ZIP:** 02021

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Avista Healthcare Public Acquisition Corp.
- **DATE OF NAME CHANGE:** 20151215

?xml version='1.0' encoding='ASCII'? 8-K

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**Washington, D.C. 20549** 

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**FORM** 8-K

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**CURRENT REPORT** 

**Pursuant to Section 13 or 15(d)** 

**of the Securities Exchange Act of 1934** 

**Date of Report (Date of Earliest Event Reported):** May 7, 2026

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ORGANOGENESIS HOLDINGS INC.

**(Exact Name of Registrant as specified in its charter)** 

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---

| | | |
|:---|:---|:---|
| Delaware | 001-37906 | 98-1329150 |
| **(State or Other Jurisdiction**<br>**of Incorporation)** | **(Commission**<br>**File Number)** | **(IRS Employer**<br>**Identification No.)** |
| 85 Dan Road<br>Canton**,** MA |  | 02021 |
| **(Address of principal executive offices)** |  | **(Zip Code)** |

---

(781) 575-0775

**(Registrant's telephone number, including area code)** 

**Not Applicable** 

**(Registrant's name or former address, if change since last report)** 

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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

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| | | |
|:---|:---|:---|
| **Title of each class** | **Trading**<br>**Symbol(s)** | **Name of each exchange on which registered** |
| Class A Common Stock, $0.0001 par value | ORGO | Nasdaq **Capital Market** |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging Growth Company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards pursuant to Section 13(a) of the Exchange Act. ☐

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**Item 2.02 Results of Operations and Financial Condition.** 

On May 7, 2026, the Company announced via press release its results for the fiscal first quarter ended March 31, 2026. A copy of the Company's press release is hereby furnished to the Commission and incorporated herein by reference as Exhibit 99.1.

The information in the press release attached as Exhibit 99.1 is intended to be furnished and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such filing.

**Item 9.01. Financial Statements and Exhibits.** 

**(d) Exhibits** 

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| | |
|:---|:---|
| **Exhibit**<br>**No.** | **Description** |
| 99.1 | [<u>Press Release dated May 7, 2026</u>](orgo-ex99_1.htm) |
| 104 | Cover Page Interactive Data File (embedded within the Inline XBRL document) |

---

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**SIGNATURE** 

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | |
|:---|:---|
| Organogenesis Holdings Inc. | Organogenesis Holdings Inc. |
| By: | /s/ Lori Freedman |
| Name: | Lori Freedman |
| Title: | Chief Administrative and Legal Officer |

---

Date: May 7, 2026

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## Exhibit 99.1

**<u>Exhibit 99.1</u>**

![img36819578_0.jpg](img36819578_0.jpg)

**FOR IMMEDIATE RELEASE**

**Organogenesis Holdings Inc. Reports First Quarter 2026 Financial Results**

**CANTON, Mass.,** (May 7, 2026) -- Organogenesis Holdings Inc. (Nasdaq: ORGO), a leading regenerative medicine and tissue innovations company focused on empowering healing through the development, manufacture, and sale of product solutions for the Advanced Wound Care and Surgical & Sports Medicine markets, today reported financial results for the first quarter ended March 31, 2026.

**<u>First Quarter 2026 Financial Results Summary:</u>**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Net revenue of $36.3 million for the first quarter of 2026, a decrease of $50.4 million compared to net revenue of $86.7 million for the first quarter of 2025. Net revenue for the first quarter of 2026 consists of:

oNet revenue from Advanced Wound Care products of $29.5 million, a decrease of 63% from the first quarter of 2025.

oNet revenue from Surgical & Sports Medicine products of $6.8 million, consistent with the first quarter of 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Net loss of $53.2 million for the first quarter of 2026, compared to a net loss of $18.8 million for the first quarter of 2025, an increase in net loss of $34.3 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Adjusted net loss of $43.7 million for the first quarter of 2026, compared to an adjusted net loss of $13.4 million for the first quarter of 2025, an increase in adjusted net loss of $30.3 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Adjusted EBITDA loss of $48.2 million for the first quarter of 2026, compared to Adjusted EBITDA loss of $12.5 million for the first quarter of 2025, an increase in EBITDA loss of $35.6 million.

"The first quarter presented a challenging start to the year, as expected; however, we remain well positioned to navigate this period of unprecedented disruption and continue to expect to drive significant market share gains in the second half of 2026," said Gary S. Gillheeney, Sr., President, Chief Executive Officer, and Chair of the Board for Organogenesis. "We remain confident in the long-term opportunity for Organogenesis, supported by the largest, most comprehensive portfolio across multiple FDA classifications, a significant achievement with the ReNu BLA submission, and an ever-expanding body of clinical evidence."

------

**<u>First Quarter 2026 Financial Results:</u>**

---

| | | | |
|:---|:---|:---|:---|
|  | **Three Months Ended March 31,** | **Three Months Ended March 31,**<br>**Change** | **Change** |
|  | **2026** | **2025** | **%** |
|  | **(in thousands, except for percentages)** | **(in thousands, except for percentages)** | **(in thousands, except for percentages)** |
| Advanced Wound Care | $29482 | $79927) | (63%) |
| Surgical & Sports Medicine | 6768 | 6766 | 0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Net product revenue | $36250 | $86693) | (58%) |

---

Net product revenue for the first quarter of 2026 was $36.3 million, compared to $86.7 million for the first quarter of 2025, a decrease of $50.4 million, or 58%. The decrease in net product revenue was driven by a decrease of $50.4 million, or 63%, in net product revenue for Advanced Wound Care products.

Gross profit for the first quarter of 2026 was $10.5 million, or 29% of net product revenue, compared to $63.0 million, or 73% of net product revenue for the first quarter of 2025, a decrease of $52.5 million, or 83%.

Operating expenses for the first quarter of 2026 were $106.1 million compared to $113.4 million for the first quarter of 2025, a decrease of $7.3 million, or 6%. Cost of goods sold was $25.8 million for the first quarter of 2026, compared to $23.7 million for the first quarter of 2025, an increase of $2.0 million, or 9%. Selling, general and administrative expenses were $65.2 million for the first quarter of 2026, compared to $72.5 million for the first quarter of 2025, a decrease of $7.3 million, or 10%. R&D expense was $15.2 million for the first quarter of 2026, compared to $10.6 million for the first quarter of 2025, an increase of $4.5 million, or 42%. For the three months ended March 31, 2025, the Company recorded write-down expenses of $6.6 million.

Operating loss for the first quarter of 2026 was $68.9 million, compared to an operating loss of $26.7 million for the first quarter of 2025, an increase in operating loss of $42.1 million.

Total other income, net, for the first quarter of 2026 was $0.4 million, compared to $1.0 million for the first quarter of 2025, a decrease of $0.5 million.

Net loss for the first quarter of 2026 was $53.2 million, or $(0.44) per share, compared to net loss of $18.8 million, or $(0.17) per share, for the first quarter of 2025, an increase in net loss of $34.3 million, or $(0.27) per share.

Adjusted net loss was $43.7 million for the first quarter of 2026, compared to adjusted net loss of $13.4 million for the first quarter of 2025, an increase in adjusted net loss of $30.3 million.

Adjusted EBITDA loss was $48.2 million for the first quarter of 2026, compared to Adjusted EBITDA loss of $12.5 million for the first quarter of 2025, an increase in adjusted EBITDA loss of $35.6 million.

Non-GAAP operating loss was $56.0 million for the first quarter of 2026, compared to non-GAAP operating loss of $19.3 million for the first quarter of 2025, an increase in non-GAAP operating loss of $36.7 million.

As of March 31, 2026, the Company had $92.1 million in cash, cash equivalents and restricted cash and no outstanding debt obligations, compared to $94.3 million in cash, cash equivalents and restricted cash and no outstanding debt obligations as of December 31, 2025.

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**Fiscal Year 2026 Outlook:**

For the year ending December 31, 2026, the Company now expects:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Total net revenue between $270.0 million and $310.0 million, representing a decline in the range of 45% to 52%, as compared to total net revenue of $564.2 million for the year ended December 31, 2025.

oThe 2026 total net revenue guidance range assumes a sequential improvement in revenue trends in the second quarter, however, at a more measured rate versus what the prior guidance assumed resulting in a first half revenue decline in the range of approximately 52% to 49% year over year. We continue to expect strong sequential revenue growth in the third and fourth quarters of 2026, however, the low-end of the guidance range now assumes a more prolonged recovery in market-related headwinds resulting in a second half revenue decline similar to the first half of 2026.

**<u>First Quarter Earnings Conference Call:</u>**

Management will host a conference call at 5:00 p.m. Eastern Time on May 7th to discuss the results of the quarter, and to provide a corporate update with a question and answer session. Those who would like to participate may access the live webcast here, or access the teleconference here. The live webcast can also be accessed via the company's website at investors.organogenesis.com. The webcast will be archived on the company website for approximately one year.

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**ORGANOGENESIS HOLDINGS INC.** 

**UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS** 

**(amounts in thousands, except share and per share data)**

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| | | |
|:---|:---|:---|
|  | **March 31,** | **December 31,** |
|  | **2026** | **2025** |
| **Assets** |  |  |
| Current assets: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cash and cash equivalents | $91379 | $93679 |
| &nbsp;&nbsp;&nbsp;&nbsp;Restricted cash | 720 | 652 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accounts receivable, net | 116908 | 217451 |
| &nbsp;&nbsp;&nbsp;&nbsp;Inventories, net | 28425 | 29627 |
| &nbsp;&nbsp;&nbsp;&nbsp;Asset held for sale | 2425 | 2425 |
| &nbsp;&nbsp;&nbsp;&nbsp;Prepaid expenses and other current assets | 28644 | 18354 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current assets | 268501 | 362188 |
| Property and equipment, net | 104078 | 103711 |
| Intangible assets, net | 3437 | 9145 |
| Goodwill | 28772 | 28772 |
| Operating lease right-of-use assets, net | 53742 | 55749 |
| Deferred tax asset, net | 45333 | 29962 |
| Other assets | 16129 | 9203 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total assets | $519992 | $598730 |
| **Liabilities, Redeemable Convertible Preferred Stock, and Stockholders' Equity** |  |  |
| Current liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Current portion of finance lease obligations | $508 | $9435 |
| &nbsp;&nbsp;&nbsp;&nbsp;Current portion of operating lease obligations - related party | 4451 | 4258 |
| &nbsp;&nbsp;&nbsp;&nbsp;Current portion of operating lease obligations | 4764 | 4949 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accounts payable | 28615 | 31949 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accrued expenses and other current liabilities | 37683 | 49533 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current liabilities | 76021 | 100124 |
| Finance lease obligations, net of current portion | 12358 | 12788 |
| Operating lease obligations, net of current portion - related party | 26993 | 28237 |
| Operating lease obligations, net of current portion | 21787 | 22470 |
| Other liabilities | 1486 | 1193 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total liabilities | 138645 | 164812 |
| Commitments and contingencies (Note 15) |  |  |
| Series A redeemable convertible preferred stock, $0.0001 par value; 130,000 shares authorized, issued and outstanding at March 31, 2026 and December 31, 2025; liquidation preference of $145,061 and $142,217 at March 31, 2026 and December 31, 2025, respectively. | 136792 | 133789 |
| Stockholders' equity: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Preferred stock, $0.0001 par value; 870,000 shares authorized; none issued or outstanding |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Common stock, $0.0001 par value; 400,000,000 shares authorized; 129,403,096 and 127,680,424 shares issued; 128,674,548 and 126,951,876 shares outstanding at March 31, 2026 and December 31, 2025, respectively. | 13 | 13 |
| &nbsp;&nbsp;&nbsp;&nbsp;Additional paid-in capital | 300776 | 303194 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accumulated deficit | (56234) | (3078) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total stockholders' equity | 244555 | 300129 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total liabilities, redeemable convertible preferred stock, and stockholders' equity | $519992 | $598730 |

---

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**ORGANOGENESIS HOLDINGS INC. UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS**

**(amounts in thousands, except share and per share data)**

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| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| Revenue: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Net product revenue | $36250 | $86693 |
| &nbsp;&nbsp;&nbsp;&nbsp;Grant income | 978 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total revenue | 37228 | 86693 |
| Operating expenses: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of goods sold | 25772 | 23723 |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative | 65186 | 72509 |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development | 15161 | 10640 |
| &nbsp;&nbsp;&nbsp;&nbsp;Write-down to fair value for asset held for sale |  | 6567 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | 106119 | 113439 |
| Loss from operations | (68891) | (26746) |
| Other income, net: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Interest income, net | 380 | 961 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income, net | 38 | 2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total other income, net | 418 | 963 |
| Net loss before income taxes | (68473) | (25783) |
| Income tax benefit | 15317 | 6940 |
| Net loss and comprehensive loss | (53156) | (18843) |
| &nbsp;&nbsp;Accretion of redeemable convertible preferred stock to redemption value | (159) | (121) |
| &nbsp;&nbsp;Cumulative dividend on redeemable convertible preferred stock | (2844) | (2627) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net loss attributable to common stockholders | $(56159) | $(21591) |
| Net loss, per share: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic and diluted | $(0.44) | $(0.17) |
| Weighted-average common shares outstanding |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic and diluted | 127797013 | 126295642 |

---

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**ORGANOGENESIS HOLDINGS INC. UNAUDITED CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS**

**(amounts in thousands, except share and per share data)**

---

| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| **Cash flows from operating activities:** |  |  |
| Net loss | $(53156) | $(18843) |
| Adjustments to reconcile net loss to net cash provided by (used in) operating activities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Depreciation and amortization | 4174 | 3444 |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of intangible assets | 5708 | 842 |
| &nbsp;&nbsp;&nbsp;&nbsp;Reduction in the carrying value of right-of-use assets | 2488 | 1997 |
| &nbsp;&nbsp;&nbsp;&nbsp;Non-cash interest expense | 91 | 69 |
| &nbsp;&nbsp;&nbsp;&nbsp;Deferred tax benefit | (15371) | (1266) |
| &nbsp;&nbsp;&nbsp;&nbsp;Provision (adjustment) recorded for credit losses | (3959) | 873 |
| &nbsp;&nbsp;&nbsp;&nbsp;Loss on disposal of property and equipment | - | 19 |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjustment for excess and obsolete inventories | 6990 | 3709 |
| &nbsp;&nbsp;&nbsp;&nbsp;Stock-based compensation | 3636 | 3367 |
| &nbsp;&nbsp;&nbsp;&nbsp;Write-down to fair value for asset held for sale |  | 6567 |
| &nbsp;&nbsp;&nbsp;&nbsp;Changes in operating assets and liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accounts receivable | 104502 | 5668 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Inventories | (8730) | (8732) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Prepaid expenses and other current assets and other assets | (1655) | (5123) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Operating leases | (2400) | (2037) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accounts payable | (2003) | (2496) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accrued expenses and other current liabilities | (19481) | (7993) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Other liabilities | 293 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash provided by (used in) operating activities | 21127 | (19935) |
| **Cash flows from investing activities:** |  |  |
| Purchases of property and equipment | (3146) | (3626) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash used in investing activities | (3146) | (3626) |
| **Cash flows from financing activities:** |  |  |
| Landlord assets under construction, net of tenant allowance | (7322) |  |
| Payments of withholding taxes in connection with RSUs vesting | (3051) | (1796) |
| Proceeds from the exercise of stock options | - | 25 |
| Principal repayments of finance lease obligations | (9840) | (285) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash used in financing activities | (20213) | (2056) |
| **Change in cash, cash equivalents and restricted cash** | (2232) | (25617) |
| Cash, cash equivalents, and restricted cash, beginning of period | 94331 | 136151 |
| Cash, cash equivalents, and restricted cash, end of period | $92099 | $110534 |
| **Supplemental disclosure of non-cash investing and financing activities:** |  |  |
| Accretion to redemption value and cumulative dividends on redeemable convertible preferred stock | $3003 | $2748 |
| Changes in purchases of property and equipment included in accounts payable and accrued expenses and other current liabilities | $39 | $172 |
| Right-of-use assets obtained through finance lease obligations | $483 | $— |
| Landlord asset additions included in accounts payable and accrued expenses and other current liabilities, net of tenant allowances | $4067 | $— |
| Right-of-use assets obtained through operating lease obligations | $- | $1642 |

---

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**<u>Non-GAAP Financial Measures</u>**

Our management uses financial measures that are not in accordance with generally accepted accounting principles in the United States, or GAAP, in addition to financial measures in accordance with GAAP to evaluate our operating results. These non-GAAP financial measures should be considered supplemental to, and not a substitute for, our reported financial results prepared in accordance with GAAP. Our management uses Adjusted EBITDA, adjusted net income (loss) and non-GAAP operating income (loss) to evaluate our operating performance and trends and make planning decisions. Our management believes Adjusted EBITDA, adjusted net income (loss) and non-GAAP operating income (loss) help identify underlying trends in our business that could otherwise be masked by the effect of the items that we exclude. Accordingly, we believe that Adjusted EBITDA, adjusted net income (loss) and non-GAAP operating income (loss) provide useful information to investors and others in understanding and evaluating our operating results, enhancing the overall understanding of our past performance and prospects, and allowing for greater transparency with respect to key financial metrics used by our management in its financial and operational decision-making.

*Adjusted EBITDA*

Adjusted EBITDA consists of GAAP net loss excluding: (i) interest (income) expense, net, (ii) income tax (benefit), (iii) depreciation and amortization, (iv) amortization of intangible assets, (v) stock-based compensation expense, and (vi) additional infrequently occurring adjustments described in more detail below.

The following table presents a reconciliation of GAAP net loss to non-GAAP EBITDA and non-GAAP Adjusted EBITDA, for the periods presented:

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| | | |
|:---|:---|:---|
|  | **Three Months Ended March 31,** | **Three Months Ended March 31,** |
|  | **2026** | **2025** |
|  | **(Unaudited, in thousands)** | **(Unaudited, in thousands)** |
| Net loss | $(53156) | $(18843) |
| &nbsp;&nbsp;&nbsp;&nbsp;Interest income, net | (380) | (961) |
| &nbsp;&nbsp;&nbsp;&nbsp;Income tax benefit | (15317) | (6940) |
| &nbsp;&nbsp;&nbsp;&nbsp;Depreciation and amortization | 4174 | 3444 |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of intangible assets (1) | 5708 | 842 |
| EBITDA | (58971) | (22458) |
| &nbsp;&nbsp;&nbsp;&nbsp;Stock-based compensation expense | 3636 | 3367 |
| &nbsp;&nbsp;&nbsp;&nbsp;Inventory write-downs (2) | 3327 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring charge (3) | 3858 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Write-down to fair value for asset held for sale (4) |  | 6567 |
| Adjusted EBITDA | $(48150) | $(12524) |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)Amount includes $4.9 million accelerated amortization of intangible assets due to a facility closure.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)Amount reflects inventory write-down adjustments for excess and obsolete inventory resulting from LCD regulatory changes of $3.3 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)Amount reflects employee severance and benefits as well as other exit costs associated with the Company's restructuring activities of $2.8 million and inventory write-down adjustments for excess and obsolete inventory resulting from a facility closure of $1.0 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4)Amount reflects the fair value adjustment of a purchased building classified as held for sale.

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*Adjusted Net Loss*

Adjusted net loss is defined as GAAP net loss plus (i) amortization of intangible assets and (ii) additional infrequently occurring adjustments described in more detail below, less the estimated tax on these adjustments.

The following table presents a reconciliation of GAAP net loss to non-GAAP adjusted net loss, for the periods presented:

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| | | |
|:---|:---|:---|
|  | **Three Months Ended March 31,** | **Three Months Ended March 31,** |
|  | **2026** | **2025** |
|  | **(Unaudited, in thousands)** | **(Unaudited, in thousands)** |
| Net loss | $(53156) | $(18843) |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of intangible assets (1) | 5708 | 842 |
| &nbsp;&nbsp;&nbsp;&nbsp;Inventory write-downs (2) | 3327 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring charge (3) | 3858 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Write-down to fair value for asset held for sale (4) |  | 6567 |
| &nbsp;&nbsp;&nbsp;&nbsp;Tax on above | (3481) | (2000) |
| Adjusted net loss | $(43744) | $(13434) |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)Amount includes $4.9 million accelerated amortization of intangible assets due to a facility closure.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)Amount reflects inventory write-down adjustments for excess and obsolete inventory resulting from LCD regulatory changes of $3.3 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)Amount reflects employee severance and benefits as well as other exit costs associated with the Company's restructuring activities of $2.8 million and inventory write-down adjustments for excess and obsolete inventory resulting from a facility closure of $1.0 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4)Amount reflects the fair value adjustment of a purchased building classified as held for sale.

*Non-GAAP Operating Loss*

Non-GAAP operating loss is defined as GAAP loss from operations plus (i) amortization of intangible assets and (ii) additional infrequently occurring adjustments described in more detail below.

The following table presents a reconciliation of GAAP net loss from operations to non-GAAP operating loss, for the periods presented:

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| | | |
|:---|:---|:---|
|  | **Three Months Ended March 31,** | **Three Months Ended March 31,** |
|  | **2026** | **2025** |
|  | **(Unaudited, in thousands)** | **(Unaudited, in thousands)** |
| Loss from operations | $(68891) | $(26746) |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of intangible assets (1) | 5708 | 842 |
| &nbsp;&nbsp;&nbsp;&nbsp;Inventory write-downs (2) | 3327 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring charge (3) | 3858 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Write-down to fair value for asset held for sale (4) |  | 6567 |
| Non-GAAP operating loss | $(55998) | $(19337) |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)Amount includes $4.9 million accelerated amortization of intangible assets due to a facility closure.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)Amount reflects inventory write-down adjustments for excess and obsolete inventory resulting from LCD regulatory changes of $3.3 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)Amount reflects employee severance and benefits as well as other exit costs associated with the Company's restructuring activities of $2.8 million and inventory write-down adjustments for excess and obsolete inventory resulting from a facility closure of $1.0 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4)Amount reflects the fair value adjustment of a purchased building classified as held for sale.

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**Forward-Looking Statements**

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements relate to expectations or forecasts of future events. Forward-looking statements may be identified by the use of words such as "forecast," "intend," "seek," "target," "anticipate," "believe," "expect," "estimate," "plan," "outlook," and "project" and other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. Such forward-looking statements include statements relating to the Company's expected revenue, competitive positioning and long-term opportunities. Forward-looking statements with respect to the operations of the Company, strategies, prospects, and other aspects of the business of the Company are based on current expectations that are subject to known and unknown risks and uncertainties, which could cause actual results or outcomes to differ materially from expectations expressed or implied by such forward-looking statements. These factors include, but are not limited to: (1) the impact of any changes to the coverage and reimbursement levels for the Company's products, particularly in light of CMS' updated 2026 Medicare reimbursement and coverage changes; (2) the Company faces significant and continuing competition, which could adversely affect its business, results of operations and financial condition; (3) rapid technological change could cause the Company's products to become obsolete and if the Company does not enhance its product offerings through its research and development efforts, it may be unable to effectively compete; (4) to be commercially successful, the Company must convince physicians that its products are safe and effective alternatives to existing treatments and that its products should be used in their procedures; (5) the Company's ability to raise funds to expand its business; (6) the Company has incurred losses in the prior periods and may incur losses in the future; (7) changes in applicable laws or regulations; (8) the possibility that the Company may be adversely affected by other economic, business, and/or competitive factors; (9) the Company's ability to maintain production or obtain supply of its products in sufficient quantities to meet demand; (10) the Company's ability to build out its Smithfield, Rhode Island facility on time and on budget; (11) whether the Company is able to obtain regulatory approval for and successfully commercialize ReNu; and (12) other risks and uncertainties described in the Company's filings with the Securities and Exchange Commission, including Item 1A (Risk Factors) of the Company's Form 10-K for the year ended December 31, 2025 and its subsequently filed periodic reports. You are cautioned not to place undue reliance upon any forward-looking statements, which speak only as of the date made. Although it may voluntarily do so from time to time, the Company undertakes no commitment to update or revise the forward-looking statements, whether as a result of new information, future events or otherwise, except as required by applicable securities laws.

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**About Organogenesis Holdings Inc.** 

Organogenesis Holdings Inc. is a leading regenerative medicine and tissue innovations company focused on empowering healing through the development, manufacture, and sale of solutions for the Advanced Wound Care and Surgical & Sports Medicine markets. Organogenesis offers a comprehensive portfolio of innovative regenerative products to address patient needs across the continuum of care. For more information, visit www.organogenesis.com.

**Investor Inquiries:**<br>ICR Healthcare

Mike Piccinino, CFA

<u>OrganoIR@icrinc.com</u>

**Press and Media Inquiries:**<br>Organogenesis

<u>communications@organo.com</u> 

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