# EDGAR Filing Document

**Accession Number:** 0001521036
**File Stem:** 0001193125-26-210369
**Filing Date:** 2026-5
**Character Count:** 31058
**Document Hash:** d55501584f5daa9a8eaffbfb57a484b7
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-210369.hdr.sgml**: 20260507

**ACCESSION NUMBER**: 0001193125-26-210369

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 11

**CONFORMED PERIOD OF REPORT**: 20260507

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20260507

**DATE AS OF CHANGE**: 20260507

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Lantheus Holdings, Inc.
- **CENTRAL INDEX KEY:** 0001521036
- **STANDARD INDUSTRIAL CLASSIFICATION:** IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 352318913
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-36569
- **FILM NUMBER:** 26950923

**BUSINESS ADDRESS:**
- **STREET 1:** 331 TREBLE COVE ROAD
- **CITY:** NORTH BILLERICA
- **STATE:** MA
- **ZIP:** 01862
- **BUSINESS PHONE:** 978 671-8001

**MAIL ADDRESS:**
- **STREET 1:** 331 TREBLE COVE ROAD
- **CITY:** NORTH BILLERICA
- **STATE:** MA
- **ZIP:** 01862

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Lantheus MI Holdings, Inc.
- **DATE OF NAME CHANGE:** 20110517

?xml version='1.0' encoding='ASCII'? 8-K

**UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549**

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## FORM 8-K

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**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934**

**Date of Report (Date of earliest event reported):** May 07, 2026<br>

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LANTHEUS HOLDINGS, INC.

**(Exact name of Registrant as Specified in Its Charter)**

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| | | |
|:---|:---|:---|
| Delaware | 001-36569 | 35-2318913 |
| **(State or Other Jurisdiction<br>of Incorporation)** | **(Commission File Number)** | **(IRS Employer<br>Identification No.)** |
| 201 Burlington Road<br>South Building |  |  |
| Bedford**,** Massachusetts |  | 01730 |
| **(Address of Principal Executive Offices)** |  | **(Zip Code)** |

---

**Registrant's Telephone Number, Including Area Code:** (978) 671-8001<br>

Not Applicable

**(Former Name or Former Address, if Changed Since Last Report)**

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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

**Securities registered pursuant to Section 12(b) of the Act:**

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| | | |
|:---|:---|:---|
| **<br>Title of each class** | **Trading<br>Symbol(s)** | **<br>Name of each exchange on which registered** |
| Common stock, par value $0.01 per share | LNTH | The Nasdaq Global Market |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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## Item 2.02 Results of Operations and Financial Condition.
On May 7, 2026, Lantheus Holdings, Inc. (the "Company") announced via press release its financial results as of and for the three months ended March 31, 2026. A copy of that press release is being furnished as Exhibit 99.1 and is hereby incorporated by reference.

The information furnished pursuant to this Item 2.02, including Exhibit 99.1, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities under that Section and shall not be deemed to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended (the "Securities Act"), or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

## Item 9.01 Financial Statements and Exhibits.
(d) Exhibits

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| | |
|:---|:---|
| **Exhibit No.** | &nbsp;&nbsp;&nbsp;**Description** |
| 99.1\* | [<u>Press release of Lantheus Holdings, Inc. dated May 7, 2026, entitled "Lantheus Reports First Quarter 2026 Financial Results and Provides Business Update"</u>](lnth-ex99_1.htm) |
| 104 | &nbsp;&nbsp;&nbsp;Cover Page Interactive Data File (embedded within the Inline XBRL document) |

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**\*** Exhibits 99.1 attached hereto are being furnished and shall not be deemed "filed" for purposes of Section 18 of the Exchange Act, as amended, or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

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**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | |
|:---|:---|
| **LANTHEUS HOLDINGS, INC.** | **LANTHEUS HOLDINGS, INC.** |
| By: | /s/ Daniel M. Niedzwiecki |
| Name: | Daniel M. Niedzwiecki |
| Title: | Chief Administrative Officer and General Counsel |

---

Date: May 7, 2026

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## Exhibit 99.1

**Exhibit 99.1**

![img66337839_0.jpg](img66337839_0.jpg)<br>

**Lantheus Reports First Quarter 2026 Financial Results and Provides Business Update**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Strong start to the year with worldwide revenue of $377.3 million in the first quarter 2026

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•GAAP fully diluted earnings per share of $1.80, compared to $1.02 in the first quarter of 2025

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Adjusted fully diluted earnings per share of $1.46, compared to $1.53 in the first quarter of 2025

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•FDA approves PYLARIFY TruVu<sup>TM</sup> (piflufolastat F18); phased geographic launch planned to begin in the fourth quarter of 2026

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•FDA tentative approval for Lutetium Lu 177 Dotatate (PNT2003); expected to be the first radioequivalent for the treatment of gastroenteropancreatic neuroendocrine tumors

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Reaffirmed previously issued corporate guidance for full year 2026 revenue and adjusted fully diluted earnings per share

BEDFORD, Mass., May 7, 2026 (GLOBE NEWSWIRE) -- Lantheus Holdings, Inc. (Lantheus or the Company) (NASDAQ: LNTH), the leading radiopharmaceutical-focused company committed to enabling clinicians to Find, Fight and Follow disease to deliver better patient outcomes, today reported financial results for its first quarter ended March 31, 2026.

"Our first quarter results demonstrate disciplined execution across the business, with strong performance from PYLARIFY, Neuraceq, and DEFINITY, and continued progress against the priorities that underpin our long-term strategy," said Mary Anne Heino, Chief Executive Officer of Lantheus. "During the quarter, we secured FDA approval for PYLARIFY TruVu and achieved tentative approval for PNT2003. For the remainder of 2026, we are focused on sustaining our leadership in PSMA PET as we prepare for the PYLARIFY TruVu conversion later this year, expanding our Alzheimer's imaging portfolio, and advancing our prioritized pipeline. At the same time, we will remain disciplined in our capital deployment, prioritizing radiodiagnostics while evaluating the best path to maximize value from our radiotherapeutic assets – all as we lay the groundwork for growth acceleration beginning in 2027."

**<u>Summary Financial Results</u>**

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| | | | |
|:---|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
| **(in millions, except per share data - unaudited)** | **2026** | **2025** | **% Change** |
| Worldwide revenue | $377.3 | $372.8 | 1.2% |
| GAAP net income | $118.4 | $72.9 | 62.3% |
| GAAP fully diluted earnings per share | $1.80 | $1.02 | 76.5% |
| Adjusted net income (non-GAAP) | $95.8 | $109.5 | (12.5%) |
| Adjusted fully diluted earnings per share (non-GAAP) | $1.46 | $1.53 | (4.6%) |

---

**<u>First Quarter 2026</u>**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Worldwide revenue increased 1.2% to $377.3 million compared to the same period in 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Sales of PYLARIFY were $240.9 million, a decrease of 6.5%.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Sales of Neuraceq were $35.4 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Sales of DEFINITY were $84.6 million, an increase of 6.8%.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Operating income decreased 20.3% to $81.3 million. Adjusted operating income (non-GAAP) decreased 10.5% to $129.1 million.

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Fully diluted earnings per share increased 76.5% to $1.80, compared to fully diluted earnings per share of $1.02 in the prior year period. Adjusted fully diluted earnings per share (non-GAAP) decreased 4.6% to $1.46, compared to $1.53 in the prior year period.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Net cash provided by operating activities and free cash flow were $125.1 million and $121.9 million, respectively.

**<u>Balance Sheet</u>** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•At March 31, 2026, the Company's cash and cash equivalents were $498.6 million, including proceeds of $31.4 million from the sale of the Company's single-photon emission computerized tomography ("SPECT") business to SHINE Technologies, LLC ("SHINE") on January 1, 2026, compared to $359.1 million at December 31, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•The Company currently has access to up to $750.0 million from a revolving line of credit.

**<u>Recent Business Highlights</u>**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Received FDA approval for PYLARIFY TruVu<sup>TM</sup>(piflufolastat F18), a new formulation of PYLARIFY<sup>®</sup>, the Company's market-leading PSMA PET imaging agent, designed to enhance manufacturing efficiency and supply flexibility; a phased geographic commercial launch is planned to begin in the fourth quarter of 2026 to align with coding, coverage, payment, and customer and PMF readiness.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Completed the divestiture of the legacy SPECT business to SHINE (effective January 1, 2026), a decisive action taken to focus on PET radiodiagnostics and simplify the Company's operating model.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Achieved FDA tentative approval for PNT2003, which upon full approval would be the first radioequivalent to Lutetium Lu 177 Dotatate for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs); launch timing will consider the following factors: the timing of FDA approval, the expiration of the 30-month Hatch-Waxman stay and disposition of the related legal proceedings, as well as manufacturing and commercial strategy to ensure launch success.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•The FDA extended the PDUFA date for LNTH-2501(Ga 68 edotreotide), the Company's PET diagnostic imaging kit for somatostatin receptor-positive neuroendocrine tumors (NETs), by three months to June 29, 2026, to allow additional time to review manufacturing-related information. This standard review extension is not related to the efficacy or safety data of LNTH-2501.

**<u>Full Year 2026 Financial Guidance</u>**

---

| | | |
|:---|:---|:---|
|  | **Guidance Issued May 7, 2026** | **Guidance Issued February 26, 2026** |
| FY 2026 Revenue | $1.4 billion - $1.45 billion | $1.4 billion - $1.45 billion |
| FY 2026 Adjusted fully diluted EPS | $5.00 - $5.25 | $5.00 - $5.25 |

---

On a forward-looking basis, the Company does not provide GAAP income per common share guidance or a reconciliation of GAAP income per common share to adjusted fully diluted EPS because the Company is unable to predict with reasonable certainty business development and acquisition related expenses, purchase accounting fair value adjustments, and any one-time, non-recurring charges. These items are uncertain, depend on various factors, and could be material to results computed in accordance with GAAP. As a result, it is the Company's view that a quantitative reconciliation of adjusted fully diluted EPS on a forward-looking basis is not available without unreasonable effort.

**Conference Call and Webcast**

As previously announced, the Company will host a conference call and webcast on Thursday, May 7, 2026, at 8:00 a.m. ET. To access the conference call or webcast, participants should register online at https://investor.lantheus.com/news-events/calendar-of-events.

A replay will be available approximately two hours after completion of the webcast and will be archived on the same web page for at least 30 days.

The conference call will include a discussion of non-GAAP financial measures. Reference is made to the most directly comparable GAAP financial measures, the reconciliation of the differences between the two financial measures, and the other information included in this press release, our Form 8-K filed with the SEC today, or otherwise available in the Investor Relations section of our website located at www.lantheus.com.

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The conference call may include forward-looking statements. See the cautionary information about forward-looking statements in the safe-harbor section of this press release.

**About Lantheus** 

Lantheus is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Germany, Switzerland, Sweden and the United Kingdom, Lantheus has been providing radiopharmaceutical solutions for 70 years. For more information, visit www.lantheus.com.

**Internet Posting of Information**

The Company routinely posts information that may be important to investors in the "Investors" section of its website at www.lantheus.com. The Company encourages investors and potential investors to consult its website regularly for important information about the Company.

**Non-GAAP Financial Measures**

The Company uses non-GAAP financial measures, such as adjusted net income and its line components; adjusted fully diluted net income per share; adjusted operating income, and free cash flow. The Company's management believes that the presentation of these measures provides useful information to investors. These measures may assist investors in evaluating the Company's operations, period over period. However, these measures may exclude items that may be highly variable, difficult to predict and of a size that could have a substantial impact on the Company's reported results of operations for a particular period. Management uses these and other non-GAAP measures internally for evaluation of the performance of the business, including the evaluation of results relative to employee performance compensation targets. Investors should consider these non-GAAP measures only as a supplement to, not as a substitute for or as superior to, measures of financial performance prepared in accordance with GAAP.

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**Safe Harbor for Forward-Looking and Cautionary Statements**

*This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, that are subject to risks and uncertainties and are made pursuant to the safe harbor provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements may be identified by their use of terms such as "advance," "believe," "continue," "could," "driving," "expect," "guidance," "maintain," "may," "on track," "plan," "potential," "predict," "progress," "should," "target," "will," "would" and other similar terms. Such forward-looking statements include our guidance for the fiscal year 2026 and our plans to successfully execute on the commercialization of marketed products, ensure launch readiness for new products, advance a focused late-stage pipeline, and allocate capital thoughtfully, and our focus mainly on our radiodiagnostic business and pursuing value-maximizing alternatives for our radiotherapeutic assets, and are based upon current plans, estimates and expectations that are subject to risks and uncertainties that could cause actual results to materially differ from those described in the forward-looking statements. The inclusion of forward-looking statements should not be regarded as a representation that such plans, estimates and expectations will be achieved. Readers are cautioned not to place undue reliance on the forward-looking statements contained herein, which speak only as of the date hereof. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by law. Risks and uncertainties that could cause our actual results to materially differ from those described in the forward-looking statements include: (i) continued market expansion, penetration and reimbursement for our established commercial products, particularly PYLARIFY, DEFINITY and Neuraceq, in a competitive environment and our ability to clinically and commercially differentiate our products; (ii) our ability to complete the technology transfer across our positron emission tomography ("PET") manufacturing facilities ("PMF") network for PYLARIFY TruVu, the new formulation of our F-18 prostate-specific membrane antigen ("PSMA") PET imaging agent approved by the U.S. Food and Drug Administration ("FDA") on March 6, 2026, to obtain FDA approval for each PMF to manufacture PYLARIFY TruVu, to obtain adequate coding, coverage and payment, including transitional pass-through payment status, for PYLARIFY TruVu and to have customers adopt PYLARIFY TruVu; (iii) the availability of raw materials, key components, equipment, manufacturing time slots, either used in the production of our products and product candidates, or by customers of our products and product candidates, including, but not limited to PET scanners for PYLARIFY, PYLARIFY TruVu, Neuraceq, MK-6240, LNTH-2501 and NAV-4694; (iv) our ability to have third parties manufacture our products and product candidates and our ability to manufacture DEFINITY in our in-house manufacturing facility, in amounts and at the times needed; (v) our ability to satisfy our obligations under our existing clinical development partnerships using Neuraceq, MK-6240 or NAV-4694 and other assets as a research tool and under the license agreements through which we have rights to those assets, and to further develop and commercialize MK-6240 and NAV-4694 as approved products; (vi) our ability to continue to successfully integrate acquisitions, including of Lantheus Biosciences Ltd. (formerly Life Molecular Imaging Limited) and Evergreen Theragnostics, Inc., which could be impacted by unforeseen expenses related to integration activities, the potential for unforeseen liabilities within those businesses, the ability to integrate disparate information technology systems, retain key talent and create a merged corporate culture that successfully realizes the full potential of the combined organization; (vii) our ability to obtain FDA approval for LNTH-2501, our investigational kit for the preparation of Gallium-68 edotreotide injection, which has been studied for use in conjunction with a PET scan to stage and localize neuroendocrine tumors in adult and pediatric patients and to successfully commercialize LNTH-2501 if approved; (viii) our ability to obtain final FDA approval for PNT2003, which received FDA tentative approval in March 2026, to be successful in the patent litigation associated with PNT2003 and to successfully commercialize PNT2003 if approved; (ix) the cost, efforts and timing for clinical development, manufacturing, regulatory approval, adequate coding, coverage and payment and successful commercialization of our newly approved products, product candidates and new clinical applications and territories for our products, in each case, that we or our strategic partners may undertake, including those investigational assets for which FDA approval has been obtained or is anticipated to be obtained this year; (x) our ability to identify opportunities to collaborate with strategic partners and to acquire or in-license additional diagnostic and therapeutic product opportunities in oncology, neurology and other strategic areas and continue to grow and advance our pipeline of products; (xi) the effect that changes to management, including the recent turnover in our leadership and senior management team, could have on our business; and (xii) the risk and uncertainties discussed in our filings with the Securities and Exchange Commission (including those described in the Risk Factors section in our Annual Reports on Form 10-K and our Quarterly Reports on Form 10-Q).* 

- Tables Follow -

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 **Lantheus Holdings, Inc.**

**Consolidated Statements of Operations**

(in thousands, except per share data – unaudited)

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| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| Revenues | $377333 | $372764 |
| Cost of goods sold | 146411 | 135064 |
| &nbsp;&nbsp;&nbsp;&nbsp;Gross profit | 230922 | 237700 |
| Operating expenses |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Sales and marketing | 52684 | 42503 |
| &nbsp;&nbsp;&nbsp;&nbsp;General and administrative | 57533 | 56816 |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development | 39379 | 36314 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | 149596 | 135633 |
| &nbsp;&nbsp;&nbsp;&nbsp;Operating income | 81326 | 102067 |
| Interest expense | 4864 | 4804 |
| Investment in equity securities - unrealized (gain) loss | (14905) | 14862 |
| Gain on sale of business, net of transaction costs | (59328) |  |
| Other income, net | (5710) | (14128) |
| &nbsp;&nbsp;&nbsp;&nbsp;Income before income taxes | 156405 | 96529 |
| Income tax expense | 37988 | 23584 |
| Net income | $118417 | $72945 |
| Net income per common share: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Basic | $1.83 | $1.06 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Diluted | $1.80 | $1.02 |
| Weighted average common shares outstanding: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Basic | 64736 | 68675 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Diluted | 65772 | 71461 |

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**Lantheus Holdings, Inc.**

**Consolidated Revenues Analysis**

(in thousands, except percent data – unaudited)

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| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months Ended** | **Three Months Ended** | **Three Months Ended** | **Three Months Ended** |
|  | **March 31,** | **March 31,** | **March 31,** | **March 31,** |
|  | **2026** | **2025** | **Change $** | **Change %** |
| &nbsp;&nbsp;PYLARIFY | $240924 | $257654 | $(16730) | (6.5)% |
| Total oncology | 240924 | 257654 | (16730) | (6.5)% |
| &nbsp;&nbsp;Neuraceq | 35439 |  | 35439 | 100.0% |
| Total neurology | 35439 |  | 35439 | 100.0% |
| &nbsp;&nbsp;DEFINITY | 84627 | 79211 | 5416 | 6.8% |
| Total cardiology | 84627 | 79211 | 5416 | 6.8% |
| Strategic partnerships and other | 16343 | 10747 | 5596 | 52.1% |
| SPECT |  | 25152 | (25152) | (100.0)% |
| Total revenues | $377333 | $372764 | $4569 | 1.2% |

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**Lantheus Holdings, Inc.**

**Reconciliation of GAAP to Non-GAAP Financial Measures**

(in thousands, except per share and percent data – unaudited)

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| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| Net income | $118417 | $72945 |
| &nbsp;&nbsp;Stock and incentive plan compensation | 16041 | 21198 |
| &nbsp;&nbsp;Amortization of acquired intangible assets | 16723 | 8016 |
| &nbsp;&nbsp;Campus consolidation costs | 12 | 60 |
| &nbsp;&nbsp;Contingent consideration fair value adjustments | (358) |  |
| &nbsp;&nbsp;Non-recurring fees | 7411 | 2478 |
| &nbsp;&nbsp;Gain on sale of business, net of transaction costs | (59328) |  |
| &nbsp;&nbsp;Strategic collaboration and license costs | (131) | 5413 |
| &nbsp;&nbsp;Investment in equity securities - unrealized (gain) loss | (14905) | 14862 |
| &nbsp;&nbsp;Acquisition, integration and divestiture-related items | 6365 | 4751 |
| &nbsp;&nbsp;Other | 80 | (4452) |
| &nbsp;&nbsp;Income tax effect of non-GAAP adjustments<sup>(a)</sup> | 5474 | (15796) |
| Adjusted net income | $95801 | $109475 |
| Adjusted net income, as a percentage of revenues | 25.4% | 29.4% |

---

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| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| Net income per share - diluted | $1.80 | $1.02 |
| &nbsp;&nbsp;Stock and incentive plan compensation | 0.24 | 0.30 |
| &nbsp;&nbsp;Amortization of acquired intangible assets | 0.25 | 0.11 |
| &nbsp;&nbsp;Campus consolidation costs | 0.00 | 0.00 |
| &nbsp;&nbsp;Contingent consideration fair value adjustments | (0.01) |  |
| &nbsp;&nbsp;Non-recurring fees | 0.11 | 0.03 |
| &nbsp;&nbsp;Gain on sale of business, net of transaction costs | (0.90) |  |
| &nbsp;&nbsp;Strategic collaboration and license costs | (0.00) | 0.07 |
| &nbsp;&nbsp;Investment in equity securities - unrealized (gain) loss | (0.23) | 0.21 |
| &nbsp;&nbsp;Acquisition, integration and divestiture-related items | 0.10 | 0.07 |
| &nbsp;&nbsp;Other | 0.00 | (0.06) |
| &nbsp;&nbsp;Income tax effect of non-GAAP adjustments<sup>(a)</sup> | 0.08 | (0.22) |
| Adjusted net income per share - diluted<sup>(b)</sup> | $1.46 | $1.53 |
| Weighted-average common shares outstanding - diluted | 65772 | 71461 |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)Represents the estimated income tax effect of the adjustments between GAAP net income and adjusted net income (non-GAAP).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)Amounts may not add due to rounding.

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**Lantheus Holdings, Inc.**

**Reconciliation of GAAP to Non-GAAP Financial Measures (Continued)**

(in thousands, except per share and percent data – unaudited)

---

| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| Operating income | $81326 | $102067 |
| &nbsp;&nbsp;Stock and incentive plan compensation | 16041 | 21198 |
| &nbsp;&nbsp;Amortization of acquired intangible assets | 16723 | 8016 |
| &nbsp;&nbsp;Campus consolidation costs | 12 | 60 |
| &nbsp;&nbsp;Contingent consideration fair value adjustments | (358) |  |
| &nbsp;&nbsp;Non-recurring fees | 7411 | 2478 |
| &nbsp;&nbsp;Strategic collaboration and license costs | (131) | 5413 |
| &nbsp;&nbsp;Acquisition, integration and divestiture-related items | 8044 | 4751 |
| &nbsp;&nbsp;Other | 80 | 275 |
| Adjusted operating income | $129148 | $144258 |
| Adjusted operating income, as a percentage of revenues | 34.2% | 38.7% |

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**Lantheus Holdings, Inc.**

**Reconciliation of Free Cash Flow**

(in thousands – unaudited)

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| | | |
|:---|:---|:---|
|  | **Three Months Ended<br>March 31,** | **Three Months Ended<br>March 31,** |
|  | **2026** | **2025** |
| Net cash provided by operating activities | $125127 | $107563 |
| Capital expenditures | (3226) | (8718) |
| &nbsp;&nbsp;Free cash flow | $121901 | $98845 |
| Net cash provided by (used in) investing activities | $25986 | $(63718) |
| Net cash used in financing activities | $(11623) | $(18219) |

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**Lantheus Holdings, Inc.**

**Condensed Consolidated Balance Sheets**

(in thousands – unaudited)

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| | | |
|:---|:---|:---|
|  | **March 31,** | **December 31,** |
|  | **2026** | **2025** |
| **Assets** |  |  |
| **Current assets:** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cash and cash equivalents | $498582 | $359121 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accounts receivable, net | 355666 | 358640 |
| &nbsp;&nbsp;&nbsp;&nbsp;Inventory, net | 61339 | 64674 |
| &nbsp;&nbsp;&nbsp;&nbsp;Income tax receivable | 1487 | 15387 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other current assets | 25214 | 21400 |
| &nbsp;&nbsp;&nbsp;&nbsp;Assets held for sale |  | 80742 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Total current assets** | 942288 | 899964 |
| Investment in equity securities | 58312 | 42213 |
| Long-term notes receivable | 92103 |  |
| Property, plant and equipment, net | 157563 | 163686 |
| Intangibles, net | 706058 | 722779 |
| Goodwill | 239399 | 239517 |
| Deferred tax assets, net | 89122 | 109196 |
| Other long-term assets | 61742 | 50044 |
| &nbsp;&nbsp;&nbsp;&nbsp;**Total assets** | $2346587 | $2227399 |
| **Liabilities and Stockholders' Equity** |  |  |
| **Current liabilities:** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Current portion of long-term debt and other borrowings | $803 | $738 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accounts payable | 45875 | 42906 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accrued expenses and other current liabilities | 286488 | 267307 |
| &nbsp;&nbsp;&nbsp;&nbsp;Liabilities held for sale |  | 22468 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Total current liabilities** | 333166 | 333419 |
| Asset retirement obligations | 139 | 138 |
| Long-term debt and other borrowings, net of current portion | 569604 | 568678 |
| Long-term deferred tax liabilities | 53508 | 54246 |
| Long-term contingent consideration liabilities, net of current portion | 72647 | 73255 |
| Other long-term liabilities | 105235 | 107866 |
| &nbsp;&nbsp;&nbsp;&nbsp;**Total liabilities** | 1134299 | 1137602 |
| **Total stockholders' equity** | 1212288 | 1089797 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Total liabilities and stockholders' equity** | $2346587 | $2227399 |

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**Contacts:** 

Mark Kinarney

Vice President, Investor Relations

978-671-8842

ir@lantheus.com

Melissa Downs

Executive Director, External Communications

646-975-2533

media@lantheus.com

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