# EDGAR Filing Document

**Accession Number:** 0001595117
**File Stem:** 0001193125-26-212851
**Filing Date:** 2026-5
**Character Count:** 28478
**Document Hash:** 46170a95bc2154b8467017c821e7ca6a
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-212851.hdr.sgml**: 20260507

**ACCESSION NUMBER**: 0001193125-26-212851

**CONFORMED SUBMISSION TYPE**: 3

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260507

**FILED AS OF DATE**: 20260507

**DATE AS OF CHANGE**: 20260507

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** George Simeon
- **CENTRAL INDEX KEY:** 0001595117

**ORGANIZATION NAME:**

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-43270
- **FILM NUMBER:** 26955774

**MAIL ADDRESS:**
- **STREET 1:** C/O SR ONE CAPITAL MANAGEMENT, LP
- **STREET 2:** 929 MAIN STREET, SUITE 200
- **CITY:** REDWOOD CITY
- **STATE:** CA
- **ZIP:** 94063
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** SR ONE CAPITAL MANAGEMENT, LLC
- **CENTRAL INDEX KEY:** 0001853723

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-43270
- **FILM NUMBER:** 26955775

**BUSINESS ADDRESS:**
- **STREET 1:** 929 MAIN STREET
- **STREET 2:** SUITE 200
- **CITY:** REDWOOD CITY
- **STATE:** CA
- **ZIP:** 94063
- **BUSINESS PHONE:** (410) 800-7503

**MAIL ADDRESS:**
- **STREET 1:** 929 MAIN STREET
- **STREET 2:** SUITE 200
- **CITY:** REDWOOD CITY
- **STATE:** CA
- **ZIP:** 94063
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Odyssey Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001882782
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 863384382
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 51 SLEEPER STREET
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02210
- **BUSINESS PHONE:** (212) 841-1000

**MAIL ADDRESS:**
- **STREET 1:** 51 SLEEPER STREET
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02210

## Ex-24.Poa

**<u>LIMITED POWER OF ATTORNEY</u>**

Know all by these presents, that the undersigned hereby makes, constitutes and appoints Sasha Keough, Karen Narolewski-Engel, James Macadam, and Alexander M. Bowling, and each of them singly, as each of the undersigned's true and lawful attorneys-in-fact with full power and authority as hereinafter described to:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.execute for and on behalf of each of the undersigned individual and entities (each, a "Filer" and collectively, the "Filers") (i) Forms 3, 4, and 5 (including amendments thereto) in accordance with Section 16(a) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules thereunder, (ii) Form 144 in accordance with Rule 144 under the Securities Act of 1933, as amended (the "Securities Act"), and (iii) Schedules 13D and 13G (including amendments thereto) in accordance with Sections 13(d) and 13(g) of the Exchange Act and the rules thereunder;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.do and perform any and all acts for and on behalf of each of the Filers which may be necessary or desirable to complete and execute any such Form 3, 4, or 5 (including amendments thereto), Form 144, or Schedule 13D or 13G (including amendments thereto) and timely file such form with the United States Securities and Exchange Commission (the "SEC") and any stock exchange or similar authority, including, but not limited to, executing a Form ID or Update Passphrase request for and on behalf of each of the undersigned and filing such applications with the SEC; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, a Filer, it being understood that the documents executed by such attorney-in-fact on behalf of such Filer pursuant to this Limited Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion.

Each of the Filers hereby grants to each attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes a Filer might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all the acts such attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this Limited Power of Attorney and the rights and powers herein granted. Each of the Filers acknowledges that each of the foregoing attorneys-in-fact, in serving in such capacity at the request of such Filer, is not assuming any of such Filer's responsibilities to comply with Sections 13 or 16 of the Exchange Act or Rule 144 under the Securities Act.

This Limited Power of Attorney shall remain in full force and effect until a Filer is no longer required to file Forms 3, 4, and 5 (including amendments thereto), Form 144, and Schedules 13D and 13G (including amendments thereto) with respect to such Filer's holdings of and transactions in securities, unless earlier revoked by such Filer in a signed writing delivered to each of the foregoing attorneys-in-fact. In addition, at such time as any attorney-in-fact resigns as attorney-in-fact by the execution of a written resignation delivered to each Filer, without any action on the part of the Filers, this Limited Power of Attorney shall be partially revoked solely with respect to such individual; such individual shall cease to be an attorney-in-fact under this Limited Power of Attorney; and the authority of the other attorneys-in-fact then existing hereunder shall remain in full force and effect.

*[Signature page follows]*

------

IN WITNESS WHEREOF, each of the undersigned has caused this Limited Power of Attorney to be executed as of this 12th day of December, 2022.

<u>/s/ Simeon George</u>______________________

Simeon George (Individually)

**SR One Capital Management, LLC,**

a Delaware limited liability company

By: <u>/s/ Simeon George</u>________________

Simeon George, Managing Member

**SR One Capital Fund I Aggregator, LP,**

a Delaware limited partnership

By: SR One Capital Partners I, LP,

a Delaware limited partnership

Its: General Partner

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: General Partner

By: <u>/s/ Simeon George</u>________________

Simeon George, Managing Member

**SR One Capital Partners I, LP,**

a Delaware limited partnership

By: SR One Capital Management, LLC

a Delaware limited liability company

Its: General Partner

By: <u>/s/ Simeon George</u>________________

Simeon George, Managing Member

------

**SR One Capital Fund II Aggregator, LP,**

a Delaware limited partnership

By: SR One Capital Partners II, LP,

a Delaware limited partnership

Its: General Partner

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: General Partner

By: **<u>/</u>**<u>s/ Simeon George</u>________________

Simeon George, Managing Member

**SR One Capital Partners II, LP,**

a Delaware limited partnership

By: SR One Capital Management, LLC

a Delaware limited liability company

Its: General Partner

By: <u>/s/ Simeon George</u>________________

Simeon George, Managing Member

**SR One Capital Opportunities Fund I, LP,**

a Delaware limited partnership

By: SR One Capital Opportunities Partners I, LP, a Delaware limited partnership

Its: General Partner

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: General Partner

By: **<u>/</u>**<u>s/ Simeon George</u>________________

Simeon George, Managing Member

------

**SR One Capital Opportunities Partners I, LP,**

a Delaware limited partnership

By: SR One Capital Management, LLC

a Delaware limited liability company

Its: General Partner

By: **<u>/s/</u>** <u>Simeon George</u>________________

Simeon George, Managing Member

**SR One Co-Invest I Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/s</u>**<u>/ Simeon George</u>________________

Simeon George, Managing Member

**SR One Co-Invest I, LLC,**

a Delaware limited liability company

By: SR One Co-Invest I Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>________________

Simeon George, Managing Member

------

**SR One Co-Invest II Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>__**______________**

Simeon George, Managing Member

**SR One Co-Invest II, LLC,**

a Delaware limited liability company

By: SR One Co-Invest II Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>_**_______________**

Simeon George, Managing Member

**SR One Co-Invest III Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

**SR One Co-Invest III, LLC,**

a Delaware limited liability company

By: SR One Co-Invest III Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest IV Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest IV, LLC,**

a Delaware limited liability company

By: SR One Co-Invest IV Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>_**_______________**

Simeon George, Managing Member

------

**SR One Co-Invest IV-A, LLC,**

a Delaware limited liability company

By: SR One Co-Invest IV Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest V Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest V, LLC,**

a Delaware limited liability company

By: SR One Co-Invest V Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>_**_______________**

Simeon George, Managing Member

------

**SR One Co-Invest VI Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest VI, LLC,**

a Delaware limited liability company

By: SR One Co-Invest VI Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest VII Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

**SR One Co-Invest VII, LLC,**

a Delaware limited liability company

By: SR One Co-Invest VII Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest VIII Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>__**______________**

Simeon George, Managing Member

**SR One Co-Invest VIII, LLC,**

a Delaware limited liability company

By: SR One Co-Invest VIII Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

**SR One Co-Invest IX Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>_**_______________**

Simeon George, Managing Member

**SR One Co-Invest IX, LLC,**

a Delaware limited liability company

By: SR One Co-Invest IX Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest X Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>_**_______________**

Simeon George, Managing Member

------

**SR One Co-Invest X, LLC,**

a Delaware limited liability company

By: SR One Co-Invest X Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XI Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XI, LLC,**

a Delaware limited liability company

By: SR One Co-Invest XI Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

**SR One Co-Invest XII Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XII, LLC,**

a Delaware limited liability company

By: SR One Co-Invest XII Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XIII Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

**SR One Co-Invest XIII, LLC,**

a Delaware limited liability company

By: SR One Co-Invest XIII Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XIV Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XIV, LLC,**

a Delaware limited liability company

By: SR One Co-Invest XIV Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

**SR One Co-Invest XV Manager, LLC,**

a Delaware limited liability company

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: **<u>/</u>**<u>s/ Simeon George</u>**________________**

Simeon George, Managing Member

**SR One Co-Invest XV, LLC,**

a Delaware limited liability company

By: SR One Co-Invest XV Manager, LLC,

a Delaware limited liability company

Its: Managing Member

By: SR One Capital Management, LLC,

a Delaware limited liability company

Its: Managing Member

By: <u>/s/ Simeon George</u>**________________**

Simeon George, Managing Member

------

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 3

### INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>SR ONE CAPITAL MANAGEMENT, LLC<br><sub>(Last) (First) (Middle)</sub><br>929 MAIN STREET<br>SUITE 200<br><sub>(Street)</sub><br>REDWOOD CITY, CA 94063<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>Odyssey Therapeutics, Inc. [ ODTX ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2026-05-07 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>George Simeon<br><sub>(Last) (First) (Middle)</sub><br>929 MAIN STREET<br>SUITE 200<br><sub>(Street)</sub><br>REDWOOD CITY, CA 94063<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>Odyssey Therapeutics, Inc. [ ODTX ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2026-05-07 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities Beneficially Owned

---

|  |  |  |  |
| --- | --- | --- | --- |
| 1. Title of Security | 2. Amount of Securities Beneficially Owned | 3. Ownership Form | 4. Nature of Indirect Beneficial Ownership |

---

## Table II - Derivative Securities Beneficially Owned

---

|  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Date Exercisable and Expiration Date (Month/Day/Year) | 2. Date Exercisable and Expiration Date (Month/Day/Year) | 3. Title and Amount of Underlying Securities | 3. Title and Amount of Underlying Securities | 4. Conversion or Exercise Price | 5. Ownership Form | 6. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 4. Conversion or Exercise Price | 5. Ownership Form | 6. Nature of Indirect Beneficial Ownership |
| Series A Convertible Preferred Stock | <sup>(1)</sup> | <sup>(1)</sup> | Common Stock | 474048 | <sup>(1)</sup> | I | See Note 2<sup>(2)</sup> |
| Series A-2 Convertible Preferred Stock | <sup>(3)</sup> | <sup>(3)</sup> | Common Stock | 139366 | <sup>(3)</sup> | I | See Note 2<sup>(2)</sup> |
| Series B Convertible Preferred Stock | <sup>(4)</sup> | <sup>(4)</sup> | Common Stock | 59692 | <sup>(4)</sup> | I | See Note 2<sup>(2)</sup> |
| Series C Convertible Preferred Stock | <sup>(5)</sup> | <sup>(5)</sup> | Common Stock | 61762 | <sup>(5)</sup> | I | See Note 2<sup>(2)</sup> |
| Series D Convertible Preferred Stock | <sup>(6)</sup> | <sup>(6)</sup> | Common Stock | 683817 | <sup>(6)</sup> | I | See Note 2<sup>(2)</sup> |
| Series D Warrants (Right to Buy) | <sup>(7)</sup> | <sup>(7)</sup> | Common Stock | 191541 | $0.10 | I | See Note 2<sup>(2)</sup> |
| Series A Convertible Preferred Stock | <sup>(1)</sup> | <sup>(1)</sup> | Common Stock | 118512 | <sup>(1)</sup> | I | See Note 8<sup>(8)</sup> |
| Series B Convertible Preferred Stock | <sup>(4)</sup> | <sup>(4)</sup> | Common Stock | 255823 | <sup>(4)</sup> | I | See Note 8<sup>(8)</sup> |
| Series B Convertible Preferred Stock | <sup>(4)</sup> | <sup>(4)</sup> | Common Stock | 204658 | <sup>(4)</sup> | I | See Note 9<sup>(9)</sup> |
| Series C Convertible Preferred Stock | <sup>(5)</sup> | <sup>(5)</sup> | Common Stock | 20582 | <sup>(5)</sup> | I | See Note 9<sup>(9)</sup> |
| Series D Convertible Preferred Stock | <sup>(6)</sup> | <sup>(6)</sup> | Common Stock | 166168 | <sup>(6)</sup> | I | See Note 9<sup>(9)</sup> |
| Series D Warrants (Right to Buy) | <sup>(7)</sup> | <sup>(7)</sup> | Common Stock | 49850 | $0.10 | I | See Note 9<sup>(9)</sup> |
| Series C Convertible Preferred Stock | <sup>(5)</sup> | <sup>(5)</sup> | Common Stock | 463106 | <sup>(5)</sup> | I | See Note 10<sup>(10)</sup> |
| Series D Convertible Preferred Stock | <sup>(6)</sup> | <sup>(6)</sup> | Common Stock | 273527 | <sup>(6)</sup> | I | See Note 10<sup>(10)</sup> |
| Series D Warrants (Right to Buy) | <sup>(7)</sup> | <sup>(7)</sup> | Common Stock | 78656 | $0.10 | I | See Note 10<sup>(10)</sup> |

---

### Footnotes:

(1) The Series A Preferred Stock is convertible into Common Stock on a 1-for-9.7170 basis at any time at the option of the holder. The Series A Preferred Stock will convert immediately prior to the closing of the Issuer's initial public offering into the number of shares shown in column 3 without payment of consideration.

(2) The securities are directly held by SR One Capital Fund I Aggregator, LP ("SR One Fund I Aggregator"). SR One Capital Partners I, LP ("SR One Partners I") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC ("SR One Capital Management") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Capital Partners I, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

(3) The Series A-2 Preferred Stock is convertible into Common Stock on a 1-for-9.3268 basis at any time at the option of the holder. The Series A-2 Preferred Stock will convert immediately prior to the closing of the Issuer's initial public offering into the number of shares shown in column 3 without payment of consideration.

(4) The Series B Preferred Stock is convertible into Common Stock on a 1-for-9.2837 basis at any time at the option of the holder. The Series B Preferred Stock will convert immediately prior to the closing of the Issuer's initial public offering into the number of shares shown in column 3 without payment of consideration.

(5) The Series C Preferred Stock is convertible into Common Stock on a 1-for-9.7170 basis at any time at the option of the holder. The Series C Preferred Stock will convert immediately prior to the closing of the Issuer's initial public offering into the number of shares shown in column 3 without payment of consideration.

(6) The Series D Preferred Stock is convertible into Common Stock on a 1-for-9.7170 basis at any time at the option of the holder. The Series D Preferred Stock will convert immediately prior to the closing of the Issuer's initial public offering into the number of shares shown in column 3 without payment of consideration.

(7) The warrants to purchase shares of Common Stock were immediately exercisable by their terms beginning on June 16, 2025. The Common Stock warrants will be exercised immediately prior to the closing of the Issuer's initial public offering into the number of shares shown in column 3 on a net exercise basis.

(8) The securities are directly held by SR One Co-Invest IV, LLC ("SR One Co-Invest IV"). SR One Co-Invest IV Manager, LLC ("SR One Co-Invest Manager") is the managing member of SR One-Co-Invest IV, and SR One Capital Management is the managing member of SR One Co-Invest Manager. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Co-Invest Manager, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

(9) The securities are directly held by SR One Co-Invest IV-A, LLC ("SR One Co-Invest IV-A"). SR One Co-Invest IV Manager is the managing member of SR One-Co-Invest IV-A, and SR One Capital Management is the managing member of SR One Co-Invest Manager. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Co-Invest Manager, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

(10) The reported securities are held directly by AMZL, LP ("AMZL"). SR One Capital SMA Partners, LP ("SR One SMA Partners") is the general partner of AMZL, and SR One Capital Management is the general partner of SR One SMA Partners. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One SMA Partners, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

**Signature:** /s/ Sasha Keough, attorney-in-fact for SR One Capital Management, LLC  
**Date:** 2026-05-07

**Signature:** /s/ Sasha Keough, attorney-in-fact for Simeon George  
**Date:** 2026-05-07

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**