# EDGAR Filing Document

**Accession Number:** 0002106939
**File Stem:** 0001951757-26-000630
**Filing Date:** 2026-4
**Character Count:** 11489
**Document Hash:** 1a6b2b9f235e1852a2e56ce87894ebcd
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001951757-26-000630.hdr.sgml**: 20260417

**ACCESSION NUMBER**: 0001951757-26-000630

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260417

**DATE AS OF CHANGE**: 20260417

**EFFECTIVENESS DATE**: 20260417

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PSP Research LLC
- **CENTRAL INDEX KEY:** 0002106939

**ORGANIZATION NAME:**
- **EIN:** 994724655
- **STATE OF INCORPORATION:** PA
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-26116
- **FILM NUMBER:** 26870153

**BUSINESS ADDRESS:**
- **STREET 1:** 113 TILLER POINT STREET
- **CITY:** LAS VEGAS
- **STATE:** NV
- **ZIP:** 89138
- **BUSINESS PHONE:** 617-483-5981

**MAIL ADDRESS:**
- **STREET 1:** 113 TILLER POINT STREET
- **CITY:** LAS VEGAS
- **STATE:** NV
- **ZIP:** 89138

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 03-31-2026

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** PSP Research LLC<br>**Address:** 113 TILLER POINT STREET<br>LAS VEGAS, NV 89138

**Form 13F File Number:** 028-26116

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Santhosh Palani<br>**Title:** Chief Compliance Officer<br>**Phone:** 617-483-5981

**Signature, Place, and Date of Signing:**

Santhosh Palani  Las Vegas, NV  04-17-2026<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 79

**Form 13F Information Table Value Total:** $141329716

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| ACADIA PHARMACEUTICALS INC | COM | 004225108 |  | 439991 | 19766 | SH |  | SOLE |  | 0 | 0 | 19766 |
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 |  | 507450 | 15000 | SH |  | SOLE |  | 0 | 0 | 15000 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 |  | 484725 | 1465 | SH |  | SOLE |  | 0 | 0 | 1465 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 |  | 150648 | 10838 | SH |  | SOLE |  | 0 | 0 | 10838 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 210425 | 2500 | SH |  | SOLE |  | 0 | 0 | 2500 |
| ARDELYX INC | COM | 039697107 |  | 479200 | 80000 | SH |  | SOLE |  | 0 | 0 | 80000 |
| ARGENX SE | SPONSORED ADR | 04016X101 |  | 468090 | 641 | SH |  | SOLE |  | 0 | 0 | 641 |
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 |  | 571825 | 2500 | SH |  | SOLE |  | 0 | 0 | 2500 |
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 |  | 444600 | 30000 | SH |  | SOLE |  | 0 | 0 | 30000 |
| AXSOME THERAPEUTICS INC. | COM | 05464T104 |  | 480862 | 2845 | SH |  | SOLE |  | 0 | 0 | 2845 |
| BRIDGEBIO PHARMA INC | COM | 10806X102 |  | 445560 | 6000 | SH |  | SOLE |  | 0 | 0 | 6000 |
| CELCUITY INC | COM | 15102K100 |  | 228280 | 2000 | SH |  | SOLE |  | 0 | 0 | 2000 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 |  | 412360 | 13000 | SH |  | SOLE |  | 0 | 0 | 13000 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 461880 | 12000 | SH |  | SOLE |  | 0 | 0 | 12000 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 |  | 392630 | 71000 | SH |  | SOLE |  | 0 | 0 | 71000 |
| COMPASS THERAPEUTICS INC | COM | 20454B104 |  | 158700 | 30000 | SH |  | SOLE |  | 0 | 0 | 30000 |
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 |  | 399520 | 11000 | SH |  | SOLE |  | 0 | 0 | 11000 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 |  | 451915 | 9500 | SH |  | SOLE |  | 0 | 0 | 9500 |
| DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 |  | 657720 | 34800 | SH |  | SOLE |  | 0 | 0 | 34800 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 |  | 419600 | 5000 | SH |  | SOLE |  | 0 | 0 | 5000 |
| DISC MEDICINE INC | COM | 254604101 |  | 511520 | 8000 | SH |  | SOLE |  | 0 | 0 | 8000 |
| DYNE THERAPEUTICS INC | COM | 26818M108 |  | 362600 | 20000 | SH |  | SOLE |  | 0 | 0 | 20000 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 |  | 204750 | 6500 | SH |  | SOLE |  | 0 | 0 | 6500 |
| ERASCA INC | COM | 29479A108 |  | 280351 | 17327 | SH |  | SOLE |  | 0 | 0 | 17327 |
| EXELIXIS INC | COM | 30161Q104 |  | 512450 | 11948 | SH |  | SOLE |  | 0 | 0 | 11948 |
| EYEPOINT INC | COM NEW | 30233G209 |  | 128900 | 10000 | SH |  | SOLE |  | 0 | 0 | 10000 |
| HALOZYME THERAPEUTICS INC | COM | 40637H109 |  | 518720 | 8026 | SH |  | SOLE |  | 0 | 0 | 8026 |
| HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 |  | 400067 | 14283 | SH |  | SOLE |  | 0 | 0 | 14283 |
| VIKING THERAPEUTICS INC | COM | 92686J106 |  | 488100 | 15000 | SH |  | SOLE |  | 0 | 0 | 15000 |
| IMMUNOCORE HLDGS PLC | ADS | 45258D105 |  | 456501 | 15141 | SH |  | SOLE |  | 0 | 0 | 15141 |
| IMMUNOME INC | COM | 45257U108 |  | 437400 | 20000 | SH |  | SOLE |  | 0 | 0 | 20000 |
| IMMUNOVANT INC | COM | 45258J102 |  | 476928 | 19200 | SH |  | SOLE |  | 0 | 0 | 19200 |
| INCYTE CORP | COM | 45337C102 |  | 498836 | 5300 | SH |  | SOLE |  | 0 | 0 | 5300 |
| INHIBRX BIOSCIENCES INC | COM | 45720N103 |  | 465702 | 6927 | SH |  | SOLE |  | 0 | 0 | 6927 |
| INTELLIA THERAPEUTICS INC | COM | 45826J105 |  | 344858 | 26900 | SH |  | SOLE |  | 0 | 0 | 26900 |
| ISHARES TR | 0-3 MNTH TREASRY | 46436E718 |  | 70462000 | 700000 | SH |  | SOLE |  | 0 | 0 | 700000 |
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 |  | 217303 | 10795 | SH |  | SOLE |  | 0 | 0 | 10795 |
| KINIKSA PHARMACEUTICALS INTL | ORD SHS CL A | G52694109 |  | 433350 | 9000 | SH |  | SOLE |  | 0 | 0 | 9000 |
| KODIAK SCIENCES INC | COM | 50015M109 |  | 381200 | 10000 | SH |  | SOLE |  | 0 | 0 | 10000 |
| KYMERA THERAPEUTICS INC | COM | 501575104 |  | 524727 | 6300 | SH |  | SOLE |  | 0 | 0 | 6300 |
| LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 |  | 217080 | 12000 | SH |  | SOLE |  | 0 | 0 | 12000 |
| ALKERMES PLC | SHS | G01767105 |  | 212160 | 6000 | SH |  | SOLE |  | 0 | 0 | 6000 |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 |  | 314082 | 600 | SH |  | SOLE |  | 0 | 0 | 600 |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 |  | 461900 | 5000 | SH |  | SOLE |  | 0 | 0 | 5000 |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 |  | 506936 | 3848 | SH |  | SOLE |  | 0 | 0 | 3848 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 |  | 480150 | 15000 | SH |  | SOLE |  | 0 | 0 | 15000 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 |  | 274400 | 7000 | SH |  | SOLE |  | 0 | 0 | 7000 |
| NURIX THERAPEUTICS INC | COM | 67080M103 |  | 444850 | 28700 | SH |  | SOLE |  | 0 | 0 | 28700 |
| OCULAR THERAPEUTIX INC | COM | 67576A100 |  | 127050 | 15000 | SH |  | SOLE |  | 0 | 0 | 15000 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 |  | 149100 | 10000 | SH |  | SOLE |  | 0 | 0 | 10000 |
| IONIS PHARMACEUTICALS INC | COM | 462222100 |  | 510612 | 6800 | SH |  | SOLE |  | 0 | 0 | 6800 |
| MONTE ROSA THERAPEUTICS INC | COM | 61225M102 |  | 460600 | 28000 | SH |  | SOLE |  | 0 | 0 | 28000 |
| ORIC PHARMACEUTICALS INC | COM | 68622P109 |  | 164710 | 13000 | SH |  | SOLE |  | 0 | 0 | 13000 |
| ORUKA THERAPEUTICS INC | COM | 687604108 |  | 243680 | 4968 | SH |  | SOLE |  | 0 | 0 | 4968 |
| PHARVARIS N V | COM | N69605108 |  | 565000 | 20000 | SH |  | SOLE |  | 0 | 0 | 20000 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 483285 | 1500 | SH |  | SOLE |  | 0 | 0 | 1500 |
| PTC THERAPEUTICS INC | COM | 69366J200 |  | 408780 | 6000 | SH |  | SOLE |  | 0 | 0 | 6000 |
| RAPPORT THERAPEUTICS INC | COM | 75383L102 |  | 438060 | 14000 | SH |  | SOLE |  | 0 | 0 | 14000 |
| ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 |  | 464132 | 19700 | SH |  | SOLE |  | 0 | 0 | 19700 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 |  | 316200 | 3000 | SH |  | SOLE |  | 0 | 0 | 3000 |
| ROYALTY PHARMA PLC | SHS CLASS A | G7709Q104 |  | 527670 | 11000 | SH |  | SOLE |  | 0 | 0 | 11000 |
| SERA PROGNOSTICS INC | CLASS A COM | 81749D107 |  | 4865271 | 2396685 | SH |  | SOLE |  | 0 | 0 | 2396685 |
| SPDR SERIES TRUST | STATE STREET SPD | 78464A870 |  | 36390277 | 284900 | SH |  | SOLE |  | 0 | 0 | 284900 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 |  | 260220 | 5159 | SH |  | SOLE |  | 0 | 0 | 5159 |
| STOKE THERAPEUTICS INC | COM | 86150R107 |  | 390720 | 12000 | SH |  | SOLE |  | 0 | 0 | 12000 |
| SUMMIT THERAPEUTICS INC | COM | 86627T108 |  | 193828 | 10223 | SH |  | SOLE |  | 0 | 0 | 10223 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 |  | 467200 | 20000 | SH |  | SOLE |  | 0 | 0 | 20000 |
| TANGO THERAPEUTICS INC | COM | 87583X109 |  | 301248 | 14400 | SH |  | SOLE |  | 0 | 0 | 14400 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 |  | 491050 | 7000 | SH |  | SOLE |  | 0 | 0 | 7000 |
| TG THERAPEUTICS INC | COM | 88322Q108 |  | 431860 | 13000 | SH |  | SOLE |  | 0 | 0 | 13000 |
| TREVI THERAPEUTICS INC | COM | 89532M101 |  | 357900 | 30000 | SH |  | SOLE |  | 0 | 0 | 30000 |
| TYRA BIOSCIENCES INC | COM | 90240B106 |  | 612800 | 16000 | SH |  | SOLE |  | 0 | 0 | 16000 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 |  | 462995 | 22100 | SH |  | SOLE |  | 0 | 0 | 22100 |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 |  | 207543 | 350 | SH |  | SOLE |  | 0 | 0 | 350 |
| SUPERNUS PHARMACEUTICALS | COM | 868459108 |  | 310140 | 6000 | SH |  | SOLE |  | 0 | 0 | 6000 |
| VERA THERAPEUTICS INC | CL A | 92337R101 |  | 402300 | 10000 | SH |  | SOLE |  | 0 | 0 | 10000 |
| XENON PHARMACEUTICALS INC | COM | 98420N105 |  | 244230 | 4200 | SH |  | SOLE |  | 0 | 0 | 4200 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 547053 | 8300 | SH |  | SOLE |  | 0 | 0 | 8300 |
| ZYMEWORKS INC | COM | 98985Y108 |  | 250400 | 10000 | SH |  | SOLE |  | 0 | 0 | 10000 |

---