# EDGAR Filing Document

**Accession Number:** 0001798749
**File Stem:** 0001193125-25-322891
**Filing Date:** 2025-12
**Character Count:** 2632
**Document Hash:** 3a4d1c7fd78a06b7f0b3c5e7d55f6531
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-322891.hdr.sgml**: 20260616

**ACCESSION NUMBER**: 0001193125-25-322891

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20251217

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Jade Biosciences, Inc.
- **CENTRAL INDEX KEY:** 0001798749
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 831377888
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 221 CRESCENT ST.
- **STREET 2:** BUILDING 23, SUITE 105
- **CITY:** WALTHAM
- **STATE:** MA
- **ZIP:** 02453
- **BUSINESS PHONE:** (781) 312-3013

**MAIL ADDRESS:**
- **STREET 1:** 221 CRESCENT ST.
- **STREET 2:** BUILDING 23, SUITE 105
- **CITY:** WALTHAM
- **STATE:** MA
- **ZIP:** 02453

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Aerovate Therapeutics, Inc.
- **DATE OF NAME CHANGE:** 20200103

**Jade Biosciences, Inc.** 

**221 Crescent Street, Building 23, Suite 105** 

**Waltham, Massachusetts 02453** 

December 17, 2025

**<u>VIA EDGAR</u>**

United States Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549-6010

Attn: Mr. Jimmy McNamara

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| | |
|:---|:---|
| Re: | **Jade Biosciences, Inc.**  |

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Registration Statement on Form S-1

File No. 333-291541

Ladies and Gentlemen:

In accordance with Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the above-referenced Registration Statement on Form S-1 (the "Registration Statement") of Jade Biosciences, Inc. (the "Company"). We respectfully request that the Registration Statement become effective as of 4:00 p.m. Eastern Time on December 19, 2025, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Latham & Watkins LLP, by calling Matt Bush at (858) 523-3962.

Thank you for your assistance in this matter.

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| | |
|:---|:---|
| Very truly yours, | Very truly yours, |
| **JADE BIOSCIENCES, INC.** | **JADE BIOSCIENCES, INC.** |
| By: | /s/ Bradford Dahms |
|  | Bradford Dahms |
|  | Chief Financial Officer |

---

cc: Tom Frohlich, *Jade Biosciences, Inc.*

Elizabeth Balta, *Jade Biosciences, Inc.*

Cheston Larson, *Latham & Watkins LLP*

Matthew T. Bush, *Latham & Watkins LLP*

Anthony Gostanian, *Latham & Watkins LLP*