# EDGAR Filing Document

**Accession Number:** 0001722926
**File Stem:** 0000950170-23-009592
**Filing Date:** 2023-3
**Character Count:** 25329
**Document Hash:** 169446d81f524c769d3b19f68eb836c9
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000950170-23-009592.hdr.sgml**: 20230324

**ACCESSION NUMBER**: 0000950170-23-009592

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 3

**CONFORMED PERIOD OF REPORT**: 20230324

**FILED AS OF DATE**: 20230324

**DATE AS OF CHANGE**: 20230324

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ASLAN Pharmaceuticals Ltd
- **CENTRAL INDEX KEY:** 0001722926
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38475
- **FILM NUMBER:** 23757633

**BUSINESS ADDRESS:**
- **STREET 1:** 83 CLEMENCEAU AVENUE
- **STREET 2:** #12-03 UE SQUARE
- **CITY:** SINGAPORE
- **STATE:** U0
- **ZIP:** 239920
- **BUSINESS PHONE:** 65 6222 4235

**MAIL ADDRESS:**
- **STREET 1:** 83 CLEMENCEAU AVENUE
- **STREET 2:** #12-03 UE SQUARE
- **CITY:** SINGAPORE
- **STATE:** U0
- **ZIP:** 239920

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**Washington, D.C. 20549** 

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**FORM 6-K** 

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**REPORT OF FOREIGN ISSUER** 

**PURSUANT TO RULE 13a-16 OR 15d-16** 

**OF THE SECURITIES EXCHANGE ACT OF 1934** 

**March 24, 2023**

**(Commission File No. 001-38475)** 

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**ASLAN PHARMACEUTICALS LIMITED** 

**(REG. NO. 289175)**

**(Translation of registrant's name into English)** 

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**CAYMAN ISLANDS**

**(Jurisdiction of incorporation or organization)**

**3 Temasek Avenue** 

**Level 18 Centennial Tower**

**Singapore 039190**

 **(Address of registrant's principal executive office)** 

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Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

Form 20-F  Form 40-F 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101 (b) (1):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Yes  No 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101 (b) (7):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Yes  No 

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**Announcement of fourth quarter and full year 2022 financial results and corporate update**

On March 24, 2023, ASLAN Pharmaceuticals Limited issued a press release announcing the financial results for the fourth quarter and full year ended December 31, 2022, and provided an update on recent corporate activities.

A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated by reference herein.

**Exhibits**

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| | |
|:---|:---|
| **Exhibit<br>Number** | **Exhibit Description** |
| 99.1 | [<u>Press release dated March 24, 2023 regarding announcement of fourth quarter and full year 2022 financial results and corporate update.</u>](asln-ex99_1.htm) |

---

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**<u>SIGNATURES</u>** 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereto duly authorized.

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| | |
|:---|:---|
| ASLAN PHARMACEUTICALS LIMITED | ASLAN PHARMACEUTICALS LIMITED |
| (Registrant) | (Registrant) |
| By: | /s/ Kiran Kumar Asarpota<br>|
| Name: | Kiran Kumar Asarpota |
| Title: | Chief Operating Officer |

---

Date: March 24, 2023

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## Ex-99

![img183322545_0.jpg](img183322545_0.jpg)

**Exhibit 99.1**

**PRESS RELEASE** 

<br> **ASLAN PHARMACEUTICALS REPORTS FOURTH QUARTER AND FULL YEAR 2022 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE** 

-**TREK-AD Phase 2b study of eblasakimab fully enrolled, topline data readout expected early July 2023**

-**Phase 2 proof-of-concept trial of farudodstat in alopecia areata expected to commence in the second quarter of 2023 with topline data readout expected in the first quarter of 2024**

-**Expected cash runway extended through at least the second quarter of 2024 with recent $20 million in financing, with potential to receive up an additional $80 million**

**San Mateo, California, and Singapore, March 24, 2023** – ASLAN Pharmaceuticals (Nasdaq: ASLN), a clinical-stage, immunology-focused biopharmaceutical company developing innovative treatments to transform the lives of patients, today announced financial results for the fourth quarter and full year ended December 31, 2022, and provided an update on recent corporate activities.

"We ended 2022 and have begun 2023 achieving a number of milestones across our clinical pipeline that position ASLAN for strong momentum throughout this year and into 2024," said **Dr Carl Firth, CEO, ASLAN Pharmaceuticals.** "At the end of 2022, we commenced dosing atopic dermatitis (AD) patients in our dupilumab-experienced (TREK-DX) trial. Most notably, we completed enrollment at the start of 2023 in our TREK-AD Phase 2b trial, testing eblasakimab as a novel treatment for moderate-to-severe AD, and we look forward to reporting topline data from this study in early July 2023. In addition, we formed a collaboration with Thermo Fisher Scientific to manufacture a high concentration formulation of eblasakimab that will allow us to administer 400mg in a single subcutaneous injection with a range of different devices."

Dr Firth continued, "We recently announced strong support from BVF Partners and additional investors on a $20 million financing, allowing us to advance farudodstat into a Phase 2, proof-of-concept study in alopecia areata (AA) in the second quarter of 2023. This is a common autoimmune disease that is associated with a severe psychological burden yet there are few effective treatments that are safe for long-term use. Farudodstat potently inhibits key drivers of AA disease pathophysiology and has the potential to be a novel, first-in-class treatment."

**Fourth quarter 2022 and recent business highlights** 

Q4 and recent clinical developments

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In March 2023, two abstracts showcasing new data on eblasakimab were accepted for poster presentation at the First International Societies for Investigative Dermatology (ISID) Meeting, taking place from May 10 to 13, 2023, in Tokyo, Japan. Posters being presented at the meeting will explore eblasakimab's efficacy in difficult to treat areas in patients with AD, such as the head and neck, and its potential for alleviating the underlying itch and hypersensitized sensory nerve fibers through multiple molecular pathways in AD.

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![img183322545_0.jpg](img183322545_0.jpg)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In February 2023, ASLAN announced the advancement of its clinical program to investigate farudodstat, a highly selective, oral dihydroorotate dehydrogenase (DHODH) inhibitor, in a Phase 2 proof-of-concept trial as a potential first-in-class treatment for AA. Farudodstat is 30-fold more potent than approved drugs in its class and has demonstrated a well-tolerated safety profile. The trial will recruit about 60 patients in the US and enrollment is expected to begin in the second quarter of 2023. The interim topline readout following the first 12-week treatment period is expected in the first quarter of 2024 and will inform the design of the subsequent Phase 2b dose-ranging study.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In February 2023, the final patient was enrolled in the TREK-AD (TRials with EblasaKimab in Atopic Dermatitis) study, a Phase 2b, dose-ranging, randomized, double-blind, placebo-controlled clinical trial of eblasakimab in adults with moderate-to-severe AD. ASLAN expects to report topline data from this study in early July 2023. The study is evaluating the efficacy and safety of eblasakimab in biologic naïve AD patients over a 16-week treatment period.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In January 2023, ASLAN and Thermo Fisher Scientific Inc (NYSE: TMO) announced a partnership to manufacture a high concentration formulation of eblasakimab for Phase 3 clinical trials. ASLAN has developed a high concentration formulation of eblasakimab, allowing up to 400mg eblasakimab to be administered in a single subcutaneous injection and suitable for use with different devices.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In December 2022, the first patient was screened in the TREK DX study of eblasakimab in adult patients with moderate-to-severe AD who have previously been treated with dupilumab. The randomized, double-blind, placebo-controlled, Phase 2 clinical trial is expected to enroll 75 patients in North America and will assess the efficacy and safety of eblasakimab in dupilumab experienced patients who have discontinued their treatment for any reason, including inadequate disease control, loss of access to drug or an adverse event.

**Corporate updates** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In March 2023, ASLAN's management team hosted a virtual farudodstat Research and Development Day with Key Opinion Leader (KOL) Brett King, MD PhD, Associate Professor of Dermatology, Yale University School of Medicine, to discuss the unmet medical need and current treatment landscape in AA. A replay of the event and presentation materials are available on the Investor Relations section of ASLAN's website.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•In February 2023, ASLAN announced that it entered into a definitive purchase agreement ("Purchase Agreement") to raise gross proceeds of approximately $20 million resulting from the sale of its ordinary shares (or pre-funded warrants) and accompanying purchase warrants, at a purchase price of $0.178 per ordinary share (or the equivalent of $4.45 per American Depositary Share ("ADS") after giving effect to the ADS Ratio Change described below to BVF Partners LP, K2 HealthVentures and certain existing investors. In addition, ASLAN has the potential to receive up to an additional $80 million in proceeds if all purchase warrants issued in connection with the Purchase Agreement are fully exercised.

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![img183322545_0.jpg](img183322545_0.jpg)

**Anticipated upcoming milestones** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•New clinical and translational data on eblasakimab will be presented at the ISID Meeting in Tokyo, Japan. Posters will be available to view at the meeting on May 10, 2023, and will be uploaded to ASLAN's website at this link following presentation.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•The first patient is expected to be enrolled in the farudodstat proof-of-concept Phase 2a study in AA in the second quarter of 2023.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Topline data data from the Phase 2b TREK-AD trial of eblasakimab is expected in early July 2023.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Topline data from the TREK-DX trial of eblasakimab is expected in the first quarter of 2024.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Topline interim data from the farudodstat Phase 2a study in AA is expected in the first quarter of 2024.

**Fourth quarter 2022 financial highlights** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Cash used in operations for the fourth quarter of 2022 was $12.0 million compared to $11.9 million in the same period in 2021.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Research and development expenses were $10.7 million in the fourth quarter of 2022 compared to $9.0 million in the fourth quarter of 2021. The increase was primarily driven by higher clinical development and manufacturing costs for eblasakimab.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•General and administrative expenses were $2.7 million in the fourth quarter of 2022 compared to $2.2 million in the fourth quarter of 2021.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Net loss attributable to stockholders for the fourth quarter of 2022 was $14.5 million compared to a net loss of $9.1 million for the fourth quarter of 2021, which included a gain of $2.3 million resulting from the dilution of JAGUAHR Therapeutics in December 2021 and recognition of its associates. The increase was primarily driven by higher clinical development and manufacturing costs for eblasakimab.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•The weighted average number of ADSs outstanding in the computation of basic loss per share for the fourth quarter of 2022 was 13.95 million (representing 348.7 million ordinary shares) compared to 13.92 million (representing 348.0 million ordinary shares) for the fourth quarter of 2021. After the ADS Ratio Change described below was effected, one ADS is the equivalent of twenty-five ordinary shares.<br>

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![img183322545_0.jpg](img183322545_0.jpg)

**Full-year 2022 financial highlights** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Cash used in operations for the year ended December 31, 2022, was $38.4 million compared to $34.0 million in 2021.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Research and development expenses were $38.0 million for the year ended December 31, 2022, compared to $22.0 million in 2021. The increase was driven primarily by the increase in clinical development and manufacturing costs for eblasakimab.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•General and administrative expenses were $9.9 million for the year ended December 31, 2022, compared to $11.8 million in 2021. The decrease in general and administrative expenses was mainly due to lower fundraising costs compared to 2021.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Net loss attributable to stockholders for the year ended December 31, 2022, was $51.4 million compared to a loss of $31.3 million in 2021. The increase was primarily due to the increase of clinical development and manufacturing costs for eblasakimab.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Cash and cash equivalents total $56.9 million as of December 31, 2022, compared to $90.2 million as of December 31, 2021. On February 28, 2023, ASLAN received gross proceeds of $20.0 million upon the closing of the Purchase Agreement with BVF and other investors. Management believes that the Company's cash and cash equivalents will be sufficient to fund operations through at least the second quarter of 2024.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•The weighted average number of ADSs outstanding in the computation of basic loss per share for the year ended December 31, 2022, was 13.9 million (representing 348.7 million ordinary shares) compared to 13.0 million (representing 325.7 million ordinary shares) for the year ended 2021.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•At the opening of trading on the Nasdaq Capital Market on March 13, 2023, the Company effected a change in the ratio of its ADSs to its ordinary shares from one (1) ADS representing five (5) ordinary shares to one (1) ADS representing twenty-five (25) ordinary shares (the "ADS Ratio Change"). For the Company's existing ADS holders, the ADS Ratio Change had the same effect as a one-for-five reverse ADS split.

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![img183322545_0.jpg](img183322545_0.jpg)

**ASLAN Pharmaceuticals Limited**

**CONSOLIDATED BALANCE SHEETS** 

**(In US Dollars, other than shares or share data)** 

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| | | |
|:---|:---|:---|
|  | **December 31, 2021<br>(audited)** | **December 31, 2022<br>(audited)** |
| **ASSETS** |  |  |
| **CURRENT ASSETS** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cash and cash equivalents | $90167967 | $56902077 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total cash and cash equivalents | 90167967 | 56902077 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other assets | 3612846 | 3976350 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current assets | $93780813 | $60878427 |
| NON-CURRENT ASSETS |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Investment in associate company | 494728 | 8587 |
| &nbsp;&nbsp;&nbsp;&nbsp;Property, plant and equipment | 34979 | 43140 |
| &nbsp;&nbsp;&nbsp;&nbsp;Right-of-use assets | 197746 | 249601 |
| &nbsp;&nbsp;&nbsp;&nbsp;Intangible assets | 9956 | 5836 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total non-current assets | 737409 | 307164 |
| **TOTAL ASSETS** | $**94518222** | $**61185591** |
| **LIABILITIES AND EQUITY** |  |  |
| CURRENT LIABILITIES |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Trade payables | $3116786 | $12784485 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other payables | 2817909 | 2325038 |
| &nbsp;&nbsp;&nbsp;&nbsp;Lease liabilities - current | 199124 | 215671 |
| &nbsp;&nbsp;&nbsp;&nbsp;Current borrowings |  | 7748831 |
| &nbsp;&nbsp;&nbsp;&nbsp;Financial liabilities at fair value through profit or loss | 223352 | 90213 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current liabilities | 6357171 | 23164238 |
| NON-CURRENT LIABILITIES |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Long-term borrowings | 30857308 | 29656133 |
| &nbsp;&nbsp;&nbsp;&nbsp;Total non-current liabilities | 30857308 | 29656133 |
| Total liabilities | 37214479 | 52820371 |
| EQUITY ATTRIBUTABLE TO STOCKHOLDERS OF THE COMPANY |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Ordinary shares | 63019962 | 63019962 |
| &nbsp;&nbsp;&nbsp;&nbsp;Capital surplus | 221467061 | 223910955 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accumulated deficits | (227004332) | (278386749) |
| &nbsp;&nbsp;&nbsp;&nbsp;Other reserves | (178948) | (178948) |
| Total equity attributable to stockholders of the Company | 57303743 | 8365220 |
| &nbsp;&nbsp;&nbsp;&nbsp;Total equity | 57303743 | 8365220 |
| **TOTAL LIABILITIES AND EQUITY** | $**94518222** | $**61185591** |

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![img183322545_0.jpg](img183322545_0.jpg)

**ASLAN Pharmaceuticals Limited**

**CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS**

**(In US Dollars, other than shares or share data)** 

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| | | | | |
|:---|:---|:---|:---|:---|
|  | **For the Three Months Ended <br>December 31 (unaudited)** | **For the Three Months Ended <br>December 31 (unaudited)** | **For the Twelve Months Ended December 31 (audited)** | **For the Twelve Months Ended December 31 (audited)** |
|  | **2021** | **2022** | **2021** | **2022** |
| OPERATING EXPENSES |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;General and administrative expenses | $(2171896) | $(2708055) | $(11825131) | $(9881993) |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development expenses | (8964318) | (10685486) | (22021321) | (38000494) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | (11136214) | (13393541) | (33846452) | (47882487) |
| LOSS FROM OPERATIONS | (11136214) | (13393541) | (33846452) | (47882487) |
| NON-OPERATING INCOME AND EXPENSES |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Interest income | 42 | 224018 | 219 | 354457 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income | 772113 | 162711 | 1108072 | 386138 |
| &nbsp;&nbsp;&nbsp;&nbsp;Gain on dilution of subsidiary and recognition of associate | 2307735 |  | 2307735 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Other gains and losses | (143731) | (571079) | 1106510 | (29583) |
| &nbsp;&nbsp;&nbsp;&nbsp;Finance costs | (747902) | (778257) | (1860954) | (3675689) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total non-operating income and expenses | 2188257 | (962607) | 2661582 | (2964677) |
| Share in losses of associated company, accounted for using equity method | (190309) | (45516) | (405712) | (436032) |
| LOSS BEFORE INCOME TAX | (9138266) | (14401664) | (31590582) | (51283196) |
| INCOME TAX EXPENSE |  | (79379) |  | (99221) |
| NET LOSS FOR THE PERIOD | (9138266) | (14481043) | (31590582) | (51382417) |
| OTHER COMPREHENSIVE LOSS |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Unrealized loss on investments |  |  |  |  |
| TOTAL COMPREHENSIVE LOSS FOR THE PERIOD | $(9138266) | $(14481043) | $(31590582) | $(51382417) |
| NET LOSS ATTRIBUTABLE TO: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Stockholders of the Company | $(9138266) | $(14481043) | $(31321618) | $(51382417) |
| &nbsp;&nbsp;&nbsp;&nbsp;Non-controlling interests |  |  | (268964) |  |
|  | $(9138266) | $(14481043) | $(31590582) | $(51382417) |
| TOTAL COMPREHENSIVE LOSS ATTRIBUTABLE TO: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Stockholders of the Company | $(9138266) | $(14481043) | $(31321618) | $(51382417) |
| &nbsp;&nbsp;&nbsp;&nbsp;Non-controlling interests |  |  | (268964) |  |
|  | $(9138266) | $(14481043) | $(31590582) | $(51382417) |
| LOSS PER ORDINARY SHARE |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic and diluted | $(0.03) | $(0.04) | $(0.10) | $(0.15) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;LOSS PER EQUIVALENT ADS - AFTER THE ADS RATIO CHANGE |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic and diluted | $(0.66) | $(1.04) | $(2.40) | $(3.68) |
| Weighted-average number of ordinary shares in the computation of basic loss per ordinary share | 348028867 | 348723365 | 325684272 | 348723365 |
| Weighted-average number of ADS in the computation of basic loss per ADS – after the Ratio Change | 13921155 | 13948935 | 13027371 | 13948935 |

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![img183322545_0.jpg](img183322545_0.jpg)

**About ASLAN Pharmaceuticals**

ASLAN Pharmaceuticals (Nasdaq: ASLN) is a clinical-stage, immunology-focused biopharmaceutical company developing innovative treatments to transform the lives of patients. ASLAN is developing eblasakimab, a potential first-in-class antibody targeting the IL-13 receptor in moderate-to-severe atopic dermatitis (AD) with the potential to improve upon current biologics used to treat allergic disease. Eblasakimab is being investigated in a global Phase 2b trial of moderate-to-severe AD patients with topline readout expected in early July 2023. ASLAN is also developing farudodstat, a potent oral inhibitor of the enzyme DHODH, as a potential first-in-class treatment for alopecia areata (AA) and plans to initiate a proof-of-concept trial in 2Q 2023. ASLAN has teams in San Mateo, California, and in Singapore. For additional information please visit the website or follow ASLAN on LinkedIn.

**Forward looking statements** 

This release contains forward-looking statements. These statements are based on the current beliefs and expectations of the management of ASLAN Pharmaceuticals Limited and/or its affiliates (the "Company"). These forward-looking statements may include, but are not limited to statements regarding the Company's business strategy and clinical development plans; the Company's plans to develop and commercialize eblasakimab and farudodstat; the safety and efficacy of eblasakimab and farudodstat; the Company's plans and expected timing with respect to clinical trials, clinical trial enrolment and clinical trial results for eblasakimab and farudodstat; the potential of eblasakimab as a first-in-class treatment for atopic dermatitis and of farudodstat as a first-in-class treatment for alopecia areata; the Company's cash runway; and the potential to receive up an additional $80 million if all purchase warrants being issued in connection with the Purchase Agreement are fully exercised. The Company's estimates, projections and other forward-looking statements are based on management's current assumptions and expectations of future events and trends, which affect or may affect the Company's business, strategy, operations, or financial performance, and inherently involve significant known and unknown risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of many risks and uncertainties, which include, unexpected safety or efficacy data observed during preclinical or clinical studies; clinical site activation rates or clinical trial enrolment rates that are lower than expected; the impact of the COVID-19 pandemic or the ongoing conflict between Ukraine and Russia and bank failures on the Company's business and the global economy; general market conditions; changes in the competitive landscape; and the Company's ability to obtain sufficient financing to fund its strategic and clinical development plans. Other factors that may cause actual results to differ from those expressed or implied in such forward-looking statements are described in the Company's US Securities and Exchange Commission filings and reports (Commission File No. 001- 38475), including the Company's Annual Report on Form 20-F filed with the US Securities and Exchange Commission on March 24, 2023. All statements other than statements of historical fact are forward-looking statements. The words "believe," "may," "might," "could," "will," "aim," "estimate," "continue," "anticipate," "intend," "expect," "plan," or the negative of those terms, and similar expressions that convey uncertainty of future events or outcomes are intended to identify estimates, projections, and other forward-looking statements. Estimates, projections, and other forward-looking statements speak only as of the date they were made, and, except to the extent required by law, the Company undertakes no obligation to update or review any estimate, projection, or forward-looking statement.

**Ends**

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![img183322545_0.jpg](img183322545_0.jpg)

**ASLAN Media and IR contacts**

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| | |
|:---|:---|
| &nbsp;&nbsp;**Emma Thompson**<br>Spurwing Communications<br>Tel: +65 6206 7350 <br>Email: ASLAN@spurwingcomms.com | &nbsp;&nbsp;**Ashley R. Robinson**<br>LifeSci Advisors, LLC<br>Tel: +1 (617) 430-7577<br>Email: arr@lifesciadvisors.com  |

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