# EDGAR Filing Document

**Accession Number:** 0001816307
**File Stem:** 0001420506-25-003142
**Filing Date:** 2025-11
**Character Count:** 12254
**Document Hash:** 409c9bfa7cd3ec9de280f986af82885e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001420506-25-003142.hdr.sgml**: 20251112

**ACCESSION NUMBER**: 0001420506-25-003142

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250930

**FILED AS OF DATE**: 20251112

**DATE AS OF CHANGE**: 20251112

**EFFECTIVENESS DATE**: 20251112

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** SILVERARC CAPITAL MANAGEMENT, LLC
- **CENTRAL INDEX KEY:** 0001816307

**ORGANIZATION NAME:**
- **EIN:** 834542901
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-21010
- **FILM NUMBER:** 251472232

**BUSINESS ADDRESS:**
- **STREET 1:** 20 PARK PLAZA
- **STREET 2:** SUITE 620
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116
- **BUSINESS PHONE:** 617.284.6952

**MAIL ADDRESS:**
- **STREET 1:** 20 PARK PLAZA
- **STREET 2:** SUITE 620
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 09-30-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** SILVERARC CAPITAL MANAGEMENT LLC<br>**Address:** 20 PARK PLAZA<br>SUITE 620<br>BOSTON, MA 02116

**Form 13F File Number:** 028-21010

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** PAUL BRAUER JR<br>**Title:** CHIEF COMPLIANCE OFFICER<br>**Phone:** 617.250.8431

**Signature, Place, and Date of Signing:**

PAUL BRAUER JR CHIEF COMPLIANCE OFFICER  BOSTON, MA  11-06-2025<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 1

**Form 13F Information Table Entry Total:** 82

**Form 13F Information Table Value Total:** $741600759

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

| No.   | Name                  | Form 13F File Number   |
|:---|:---|:---|
|  | SilverArc Capital LLC | 028-20993              |

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| AARDVARK THERAPEUTICS INC | COM | 002942100 |  | 4078861 | 306912 | SH |  | SOLE |  | 373594 | 0 | 0 |
| ABEONA THERAPEUTICS INC | COM NEW | 00289Y206 |  | 5252301 | 994754 | SH |  | SOLE |  | 994754 | 0 | 0 |
| ABIVAX SA | SPONSORED ADS | 00370M103 |  | 45820870 | 539704 | SH |  | SOLE |  | 539704 | 0 | 0 |
| AKERO THERAPEUTICS INC | COM | 00973Y108 |  | 30559837 | 643636 | SH |  | SOLE |  | 643636 | 0 | 0 |
| ALKERMES PLC | SHS | G01767105 |  | 5415390 | 180513 | SH |  | SOLE |  | 180513 | 0 | 0 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 |  | 9513000 | 700000 | SH |  | SOLE |  | 700000 | 0 | 0 |
| ARCTURUS THERAPEUTICS HLDGS | COM | 03969T109 |  | 63491 | 3445 | SH |  | SOLE |  | 3445 | 0 | 0 |
| ARCTURUS THERAPEUTICS HLDGS | PUT | 03969T959 |  | 774060 | 42000 | SH | Put | SOLE |  | 42000 | 0 | 0 |
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 |  | 10647071 | 53554 | SH |  | SOLE |  | 53554 | 0 | 0 |
| ATYR PHARMA INC | PUT | 002120952 |  | 901250 | 1250000 | SH | Put | SOLE |  | 1250000 | 0 | 0 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 |  | 9162919 | 720922 | SH |  | SOLE |  | 720922 | 0 | 0 |
| AVIDITY BIOSCIENCES INC | COM | 05370A108 |  | 36800660 | 844633 | SH |  | SOLE |  | 844633 | 0 | 0 |
| BENITEC BIOPHARMA INC | COM NEW | 08205P209 |  | 3876026 | 276267 | SH |  | SOLE |  | 276267 | 0 | 0 |
| BICARA THERAPEUTICS INC | COM | 055477103 |  | 3957069 | 250606 | SH |  | SOLE |  | 250606 | 0 | 0 |
| BIODESIX INC | COM | 09075X207 |  | 374533 | 49607 | SH |  | SOLE |  | 49607 | 0 | 0 |
| BIOGEN INC | COM | 09062X103 |  | 11265094 | 80419 | SH |  | SOLE |  | 80419 | 0 | 0 |
| BRIDGEBIO ONCOLOGY THERAPEUT | COM NEW | 107924102 |  | 5296854 | 457414 | SH |  | SOLE |  | 457414 | 0 | 0 |
| C4 THERAPEUTICS INC | COM STK | 12529R107 |  | 4212190 | 1897383 | SH |  | SOLE |  | 1897383 | 0 | 0 |
| CAMP4 THERAPEUTICS CORP | COM | 13463J101 |  | 1960782 | 653594 | SH |  | SOLE |  | 653594 | 0 | 0 |
| CAPRICOR THERAPEUTICS INC | PUT | 14070B959 |  | 1043287 | 144700 | SH | Put | SOLE |  | 144700 | 0 | 0 |
| CELCUITY INC | COM | 15102K100 |  | 4381088 | 88686 | SH |  | SOLE |  | 88686 | 0 | 0 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 |  | 9026612 | 348922 | SH |  | SOLE |  | 348922 | 0 | 0 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 |  | 3425022 | 141238 | SH |  | SOLE |  | 141238 | 0 | 0 |
| CERUS CORP | COM | 157085101 |  | 4318100 | 2715786 | SH |  | SOLE |  | 2715786 | 0 | 0 |
| CG ONCOLOGY INC | COM | 156944100 |  | 25712577 | 638346 | SH |  | SOLE |  | 638346 | 0 | 0 |
| CIDARA THERAPEUTICS INC | COM NEW | 171757206 |  | 21153576 | 220902 | SH |  | SOLE |  | 220902 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 11704477 | 815075 | SH |  | SOLE |  | 815075 | 0 | 0 |
| COGENT BIOSCIENCES INC | CALL | 19240Q901 |  | 5169600 | 360000 | SH | Call | SOLE |  | 360000 | 0 | 0 |
| COMPASS THERAPEUTICS INC | COM | 20454B104 |  | 9918958 | 2833988 | SH |  | SOLE |  | 2833988 | 0 | 0 |
| COMPUGEN LTD | ORD | M25722105 |  | 4867413 | 3311165 | SH |  | SOLE |  | 3311165 | 0 | 0 |
| CONTINEUM THERAPEUTICS INC | CL A | 21217B100 |  | 1952392 | 166161 | SH |  | SOLE |  | 166161 | 0 | 0 |
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 |  | 2082500 | 50000 | SH |  | SOLE |  | 50000 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 11596560 | 211000 | SH |  | SOLE |  | 211000 | 0 | 0 |
| DELCATH SYS INC | COM NEW | 24661P807 |  | 2186400 | 203386 | SH |  | SOLE |  | 203386 | 0 | 0 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 |  | 26559912 | 674966 | SH |  | SOLE |  | 674966 | 0 | 0 |
| DYNE THERAPEUTICS INC | COM | 26818M108 |  | 1265000 | 100000 | SH |  | SOLE |  | 100000 | 0 | 0 |
| ELUTIA INC | CL A COM | 05479K106 |  | 2537949 | 2850987 | SH |  | SOLE |  | 2850987 | 0 | 0 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 |  | 218517 | 10675 | SH |  | SOLE |  | 10675 | 0 | 0 |
| ERASCA INC | COM | 29479A108 |  | 2982404 | 1368075 | SH |  | SOLE |  | 1368075 | 0 | 0 |
| EYEPOINT PHARMACEUTICALS INC | COM NEW | 30233G209 |  | 3287119 | 230837 | SH |  | SOLE |  | 230837 | 0 | 0 |
| FRACTYL HEALTH INC | COM | 35168W103 |  | 16854000 | 10600000 | SH |  | SOLE |  | 10600000 | 0 | 0 |
| GOSSAMER BIO INC | COM | 38341P102 |  | 12568986 | 4779082 | SH |  | SOLE |  | 4779082 | 0 | 0 |
| IMMUNOVANT INC | COM | 45258J102 |  | 806000 | 50000 | SH |  | SOLE |  | 50000 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 29759378 | 206648 | SH |  | SOLE |  | 206648 | 0 | 0 |
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 |  | 16605944 | 1363378 | SH |  | SOLE |  | 1363378 | 0 | 0 |
| KINIKSA PHARMACEUTICALS INTL | ORD SHS CL A | G52694109 |  | 3452375 | 88910 | SH |  | SOLE |  | 88910 | 0 | 0 |
| KODIAK SCIENCES INC | COM | 50015M109 |  | 16370000 | 1000000 | SH |  | SOLE |  | 1000000 | 0 | 0 |
| LB PHARMACEUTICALS INC | COM SHS | 50180M108 |  | 1105300 | 70000 | SH |  | SOLE |  | 70000 | 0 | 0 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 |  | 5169977 | 778611 | SH |  | SOLE |  | 778611 | 0 | 0 |
| MBX BIOSCIENCES INC | COM | 55287L101 |  | 262500 | 15000 | SH |  | SOLE |  | 15000 | 0 | 0 |
| MERSANA THERAPEUTICS INC | COM | 59045L205 |  | 1037015 | 133636 | SH |  | SOLE |  | 133636 | 0 | 0 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 |  | 3033600 | 80000 | SH |  | SOLE |  | 80000 | 0 | 0 |
| MODULAR MED INC | COM NEW | 60785L207 |  | 447544 | 639531 | SH |  | SOLE |  | 639531 | 0 | 0 |
| MONTE ROSA THERAPEUTICS INC | COM | 61225M102 |  | 5149520 | 694942 | SH |  | SOLE |  | 694942 | 0 | 0 |
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 |  | 215100 | 30000 | SH |  | SOLE |  | 30000 | 0 | 0 |
| MOONLAKE IMMUNOTHERAPEUTICS | CALL | 61559X904 |  | 466050 | 65000 | SH | Call | SOLE |  | 65000 | 0 | 0 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 |  | 20769 | 365 | SH |  | SOLE |  | 365 | 0 | 0 |
| NUVALENT INC | COM | 670703107 |  | 32196504 | 372300 | SH |  | SOLE |  | 372300 | 0 | 0 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 |  | 9139366 | 933541 | SH |  | SOLE |  | 933541 | 0 | 0 |
| ORIC PHARMACEUTICALS INC | COM | 68622P109 |  | 23385696 | 1948808 | SH |  | SOLE |  | 1948808 | 0 | 0 |
| PHARVARIS N V | COM | N69605108 |  | 4588380 | 183903 | SH |  | SOLE |  | 183903 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 2714130 | 51210 | SH |  | SOLE |  | 51210 | 0 | 0 |
| RADIOPHARM THERANOSTICS LTD | SPONSORED ADS | 75041J101 |  | 1034481 | 187406 | SH |  | SOLE |  | 187406 | 0 | 0 |
| RAPPORT THERAPEUTICS INC | COM | 75383L102 |  | 6057196 | 203946 | SH |  | SOLE |  | 203946 | 0 | 0 |
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 |  | 37365896 | 369996 | SH |  | SOLE |  | 369996 | 0 | 0 |
| ROCKET PHARMACEUTICALS INC | *W EXP 09/02/202 | 77313F114 |  | 4109 | 104828 | SH |  | SOLE |  | 104828 | 0 | 0 |
| SCHOLAR ROCK HLDG CORP | COM | 80706P103 |  | 8711181 | 233920 | SH |  | SOLE |  | 233920 | 0 | 0 |
| SIONNA THERAPEUTICS INC | COM | 829401108 |  | 3199837 | 108801 | SH |  | SOLE |  | 108801 | 0 | 0 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 |  | 7134148 | 463708 | SH |  | SOLE |  | 463708 | 0 | 0 |
| SYNDAX PHARMACEUTICALS INC | CALL | 87164F905 |  | 769500 | 50000 | SH | Call | SOLE |  | 50000 | 0 | 0 |
| TELA BIO INC | COM | 872381108 |  | 4146555 | 2782923 | SH |  | SOLE |  | 2782923 | 0 | 0 |
| TREVI THERAPEUTICS INC | COM | 89532M101 |  | 5387419 | 588789 | SH |  | SOLE |  | 588789 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | CALL | 90400D908 |  | 15888256 | 528200 | SH | Call | SOLE |  | 528200 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | PUT | 90400D958 |  | 752000 | 25000 | SH | Put | SOLE |  | 25000 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 |  | 26558350 | 455000 | SH |  | SOLE |  | 455000 | 0 | 0 |
| UNITED THERAPEUTICS CORP DEL | PUT | 91307C952 |  | 25110679 | 59900 | SH | Put | SOLE |  | 59900 | 0 | 0 |
| UROGEN PHARMA LTD | COM | M96088105 |  | 31466796 | 1577283 | SH |  | SOLE |  | 1577283 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 11322491 | 314339 | SH |  | SOLE |  | 314339 | 0 | 0 |
| VERACYTE INC | COM | 92337F107 |  | 8094705 | 235791 | SH |  | SOLE |  | 235791 | 0 | 0 |
| VERASTEM INC | COM NEW | 92337C203 |  | 9207544 | 1042757 | SH |  | SOLE |  | 1042757 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 |  | 5600204 | 259509 | SH |  | SOLE |  | 259509 | 0 | 0 |
| ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 |  | 3119557 | 720452 | SH |  | SOLE |  | 720452 | 0 | 0 |

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