# EDGAR Filing Document

**Accession Number:** 0001385818
**File Stem:** 0001437749-25-020579
**Filing Date:** 2025-6
**Character Count:** 6796
**Document Hash:** 2da27fa540db87a3609128eda096054b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001437749-25-020579.hdr.sgml**: 20250617

**ACCESSION NUMBER**: 0001437749-25-020579

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 48

**CONFORMED PERIOD OF REPORT**: 20250617

**ITEM INFORMATION**: Regulation FD Disclosure

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20250617

**DATE AS OF CHANGE**: 20250617

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** AYTU BIOPHARMA, INC
- **CENTRAL INDEX KEY:** 0001385818
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 470883144
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38247
- **FILM NUMBER:** 251051763

**BUSINESS ADDRESS:**
- **STREET 1:** 7900 E. UNION AVENUE
- **STREET 2:** SUITE 920
- **CITY:** DENVER
- **STATE:** CO
- **ZIP:** 80237
- **BUSINESS PHONE:** (720) 437-6580

**MAIL ADDRESS:**
- **STREET 1:** 7900 E. UNION AVENUE
- **STREET 2:** SUITE 920
- **CITY:** DENVER
- **STATE:** CO
- **ZIP:** 80237

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AYTU BIOSCIENCE, INC
- **DATE OF NAME CHANGE:** 20150609

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AYTU BIOSCIENCE, INC.
- **DATE OF NAME CHANGE:** 20150609

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Rosewind CORP
- **DATE OF NAME CHANGE:** 20070110

?xml version='1.0' encoding='ASCII'? aytu20250616_8k.htm

------

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934**

**June 17, 2025**

Date of Report (Date of earliest event reported)

![logo01.jpg](logo01.jpg)

**AYTU BIOPHARMA, INC.**

(Exact name of registrant as specified in its charter)

---

| | | |
|:---|:---|:---|
| **Delaware** | **001-38247** | **47-0883144** |
| (State or other jurisdiction of incorporation) | (Commission File Number) | (IRS Employer Identification No.) |

---

**7900 East Union Avenue, Suite 920**

**Denver, CO 80237**

(Address of principal executive offices, including zip code)

**(720) 437-6580**

(Registrant's telephone number, including area code)

**Not applicable** 

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| Title of Each Class | Trading Symbol(s) | Name of Each Exchange on Which Registered |
| **Common Stock, par value $0.0001 per share** | **AYTU** | **The Nasdaq Capital Market** |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

------

**Item 7.01 Regulation FD Disclosure.**

In accordance with General Instruction B.2. of Form 8-K, the following information shall not be deemed filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall such information and exhibit be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.

On June 17, 2025, Aytu BioPharma, Inc. (the "Company") posted to its website an updated investor presentation that will be used in connection with upcoming investor meetings. The presentation includes, among other matters, information on the EXXUA™ (gepirone) extended-release tablets opportunity. A copy of the presentation is attached hereto as Exhibit 99.1 to this Current Report on Form 8-K. The presentation can also be viewed on the Company's website at https://investors.aytubio.com/ under Events & Presentations.

**Item 9.01 Financial Statements and Exhibits.**

 **(d) Exhibits.**

---

| | |
|:---|:---|
| **Exhibit** <br> **Number** | **Exhibit Description** |
| 99.1 | [Investor Presentation Dated June 2025](ex_831722.htm) |
| 104 | Cover Page Interactive Data File (embedded within the Inline XBRL document) |

---

------

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  | AYTU BIOPHARMA, INC. | AYTU BIOPHARMA, INC. |
| Date: June 17, 2025 | By: | /s/ Ryan J. Selhorn |
|  |  | Ryan J. Selhorn |
|  |  | Chief Financial Officer |

---

## Exhibit 99.1

**Exhibit 99.1**

![slide01.jpg](slide01.jpg)

------

![slide02.jpg](slide02.jpg)

------

![slide03.jpg](slide03.jpg)

------

![slide04.jpg](slide04.jpg)

------

![slide05.jpg](slide05.jpg)

------

![slide06.jpg](slide06.jpg)

------

![slide07.jpg](slide07.jpg)

------

![slide08.jpg](slide08.jpg)

------

![slide09.jpg](slide09.jpg)

------

![slide10.jpg](slide10.jpg)

------

![slide11.jpg](slide11.jpg)

------

![slide12.jpg](slide12.jpg)

------

![slide13.jpg](slide13.jpg)

------

![slide14.jpg](slide14.jpg)

------

![slide15.jpg](slide15.jpg)

------

![slide16.jpg](slide16.jpg)

------

![slide17.jpg](slide17.jpg)

------

![slide18.jpg](slide18.jpg)

------

![slide19.jpg](slide19.jpg)

------

![slide20.jpg](slide20.jpg)

------

![slide21.jpg](slide21.jpg)

------

![slide22.jpg](slide22.jpg)

------

![slide23.jpg](slide23.jpg)

------

![slide24.jpg](slide24.jpg)

------

![slide25.jpg](slide25.jpg)

------

![slide26.jpg](slide26.jpg)

------

![slide27.jpg](slide27.jpg)

------

![slide28.jpg](slide28.jpg)

------

![slide29.jpg](slide29.jpg)

------

![slide30.jpg](slide30.jpg)

------

![slide31.jpg](slide31.jpg)

------

![slide32.jpg](slide32.jpg)

------

![slide33.jpg](slide33.jpg)