# EDGAR Filing Document

**Accession Number:** 0001558569
**File Stem:** 0000000000-25-009383
**Filing Date:** 2025-8
**Character Count:** 4959
**Document Hash:** 3a6dbffa042d9f2b0f3f33f4b4309a1d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000000000-25-009383.hdr.sgml**: 20260702

**ACCESSION NUMBER**: 0000000000-25-009383

**CONFORMED SUBMISSION TYPE**: UPLOAD

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20250829

**FILED FOR**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** iSpecimen Inc.
- **CENTRAL INDEX KEY:** 0001558569
- **STANDARD INDUSTRIAL CLASSIFICATION:** SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 270480143
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** UPLOAD
- **SEC FILE NUMBER:** 333-289725

**BUSINESS ADDRESS:**
- **STREET 1:** 8 CABOT ROAD
- **STREET 2:** SUITE 1800
- **CITY:** WOBURN
- **STATE:** MA
- **ZIP:** 08101
- **BUSINESS PHONE:** 781-301-6700

**MAIL ADDRESS:**
- **STREET 1:** 8 CABOT ROAD
- **STREET 2:** SUITE 1800
- **CITY:** WOBURN
- **STATE:** MA
- **ZIP:** 08101
**PUBLIC REFERENCE ACCESSION NUMBER**: 0001213900-25-078951

## Text-Extract

```

                                                             August 29, 2025

Robert Bradley Lim
Chief Executive Officer
iSpecimen Inc.
8 Cabot Road, Suite 1800
Woburn, MA 08101

       Re: iSpecimen Inc.
           Amendment No. 1 to Registration Statement on Form S-1
           Filed August 25, 2025
           File No. 333-289725
Dear Robert Bradley Lim:

       We have conducted a limited review of your registration statement and
have the
following comment(s).

        Please respond to this letter by amending your registration statement
and providing
the requested information. If you do not believe a comment applies to your
facts and
circumstances or do not believe an amendment is appropriate, please tell us why
in your
response.

       After reviewing any amendment to your registration statement and the
information
you provide in response to this letter, we may have additional comments.

Amendment No. 1 to Registration Statement on Form S-1, filed August 25, 2025
Exhibit Index, page II-6

1.     The consent of Bush & Associates included as Exhibit 23.2 does not
include a
       reference to their audit report dated April 14, 2025. Please revise the
consent to
       appropriately reference the audit report included in the prospectus.
General

2.     We note your statements in a press release dated August 7, 2025 and
furnished
       pursuant to Item 7.01 of Form 8-K that you are looking to build an up to
$200 million
       corporate treasury reserve based on the Solana blockchain ecosystem and
that you
       have engaged WestPark Capital and BlockArrow Capital for advisory
services
       regarding this plan. However, this does not appear to be addressed in
your prospectus
       disclosure. Please revise your prospectus to provide sufficient
disclosure regarding
 August 29, 2025
Page 2

       your corporate treasury plan for investors to understand your
anticipated business
       model. Your disclosure should include a timeline of the building of your
Solana based
       treasury for the next twelve months, the amount of any cryptocurrency
you currently
       hold, the source of any anticipated funding, and any planned
acquisitions to build your
       crypto treasury. Additionally, please include appropriate risk factor
disclosure
       regarding your new business plan for a crypto treasury program.
Alternatively, if you
       no longer intend to move forward with this program, please note that in
your
       disclosure.
3.     We note the disclosure from your Current Report on Form 8-K filed June
5, 2025 that
       on June 4, 2025 you received a letter from Nasdaq notifying you that you
no longer
       complied with Nasdaq Listing Rule 5550(b)(1) and that under Nasdaq rules
you
       had 45 calendar days from the date of the notice to submit a plan to
regain
       compliance. Please revise the prospectus to provide updated disclosure
regarding this
       delisting notification.
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence
of action by the staff.

       Refer to Rules 460 and 461 regarding requests for acceleration. Please
allow adequate
time for us to review any amendment prior to the requested effective date of
the registration
statement.

      Please contact Conlon Danberg at 202-551-4466 or Margaret Sawicki at
202-551-
7153 with any other questions.

                                                           Sincerely,

                                                           Division of
Corporation Finance
                                                           Office of Industrial
Applications and
                                                           Services
cc:   Ross D. Carmel, Esq.

```

### Attached PDF Documents

**Attachment 1:** `filename1`

_No text found in this document._