# EDGAR Filing Document

**Accession Number:** 0001429260
**File Stem:** 0001104659-26-050358
**Filing Date:** 2026-4
**Character Count:** 146084
**Document Hash:** 6aaa65f6066ddc96b9020e6b360103e3
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-26-050358.hdr.sgml**: 20260428

**ACCESSION NUMBER**: 0001104659-26-050358

**CONFORMED SUBMISSION TYPE**: DEF 14A

**PUBLIC DOCUMENT COUNT**: 19

**CONFORMED PERIOD OF REPORT**: 20260617

**FILED AS OF DATE**: 20260428

**DATE AS OF CHANGE**: 20260428

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Fortress Biotech, Inc.
- **CENTRAL INDEX KEY:** 0001429260
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 205157386
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DEF 14A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-35366
- **FILM NUMBER:** 26908020

**BUSINESS ADDRESS:**
- **STREET 1:** 1111 KANE CONCOURSE
- **STREET 2:** SUITE 301
- **CITY:** BAY HARBOR ISLANDS
- **STATE:** FL
- **ZIP:** 33154
- **BUSINESS PHONE:** 781-652-4500

**MAIL ADDRESS:**
- **STREET 1:** 1111 KANE CONCOURSE
- **STREET 2:** SUITE 301
- **CITY:** BAY HARBOR ISLANDS
- **STATE:** FL
- **ZIP:** 33154

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CORONADO BIOSCIENCES INC
- **DATE OF NAME CHANGE:** 20080310

?xml version='1.0' encoding='ASCII'? FORTRESS BIOTECH, INC.

[**Table of Contents**](#TOC)

------

![Graphic](fbio-20260617xdef14a_a001.jpg)

**FORTRESS BIOTECH, INC.**

**1111 Kane Concourse, Suite 301**

**Bay Harbor Islands, FL 33154**

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**SCHEDULE 14A**

Proxy Statement Pursuant to Section 14(a) of

the Securities Exchange Act of 1934 (Amendment No.)

---

| | |
|:---|:---|
| Filed by the Registrant ☒ | Filed by the Registrant ☒ |
| Filed by a Party other than the Registrant ☐ | Filed by a Party other than the Registrant ☐ |
| Check the appropriate box: | Check the appropriate box: |
| ☐ | Preliminary Proxy Statement |
| ☐ | **Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))** |
| ☒ | Definitive Proxy Statement |
| ☐ | Definitive Additional Materials |
| ☐ | Soliciting Material under §240.14a-12 |

---

**FORTRESS BIOTECH, INC.**

(Name of Registrant as Specified in Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

---

| | |
|:---|:---|
| Payment of Filing Fee (Check the appropriate box): | Payment of Filing Fee (Check the appropriate box): |
| ☒ | No fee required |
| ☐ | Fee paid previously with preliminary materials |
| ☐ | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11 |

---

------

[**Table of Contents**](#TOC)

![Graphic](fbio-20260617xdef14a_a001.jpg)

#### FORTRESS BIOTECH, INC.
**1111 Kane Concourse, Suite 301**

**Bay Harbor Islands, FL 33154**

Dear Stockholder:

You are cordially invited to the 2026 Annual Meeting of Stockholders (the "Annual Meeting") of Fortress Biotech, Inc. (the "Company") to be held on Wednesday, June 17, 2026 at 10:00 a.m. ET. The Annual Meeting will be virtual and conducted by means of a live webcast as described below, which can be accessed at www.virtualshareholdermeeting.com/fbio2026 when you enter your 16-digit control number included with the Notice of Internet Availability of Proxy Materials (the "Internet Notice") or proxy card.

At the meeting, the stockholders will be asked to (i) elect seven directors for a term of one year, (ii) ratify the appointment of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026, and (iii) transact any other business that may properly come before the Annual Meeting or any adjournment of the Annual Meeting. You will also have the opportunity to ask questions and make comments at the meeting.

In accordance with the rules and regulations of the Securities and Exchange Commission, we are furnishing our 2026 proxy statement and annual report to stockholders for the year ended December 31, 2025 on the internet. You may have already received our Internet Notice, which was mailed on or about April 28, 2026. That notice described how you can obtain our proxy statement and annual report. You can also receive paper copies of our proxy statement and annual report upon request.

It is important that your stock be represented at the meeting regardless of the number of shares you hold. You are encouraged to specify your voting preferences via Internet or telephone or, if you received a printed copy of our proxy materials, by marking our proxy card and returning it as directed. If you do attend the meeting virtually and wish to vote live during the meeting, you may revoke your proxy at the meeting.

If you have any questions about the proxy statement or the accompanying 2025 Annual Report, please contact David Jin, our Chief Financial Officer at (781) 652-4500.

Thank you for your ongoing support of and continued interest in Fortress Biotech, Inc.

---

| |
|:---|
| Sincerely, |
| /s/ Lindsay A. Rosenwald, M.D. |
| Lindsay A. Rosenwald, M.D. |
| *Executive Chairman, Chief Executive Officer and President* |

---

April 28, 2026

Bay Harbor Islands, FL

[**Table of Contents**](#TOC)

![Graphic](fbio-20260617xdef14a_a001.jpg)

**1111 Kane Concourse, Suite 301**

**Bay Harbor Islands, FL 33154**

#### NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

#### Annual Meeting Will be Conducted Virtually
To facilitate greater shareholder access, Fortress is hosting a completely virtual Annual Meeting. You may attend the webcast of the meeting via the internet on Wednesday, June 17, 2026 at 10:00 a.m. ET, at www.virtualshareholdermeeting.com/fbio2026 when you enter your 16-digit control number included with the Internet Notice or proxy card. Instructions on how to attend and participate in the Annual Meeting via the webcast are posted on www.virtualshareholdermeeting.com/fbio2026. You will be able to vote your shares by following the instructions on the website and ask questions by using the question box on the virtual meeting platform. At the meeting, stockholders will consider and act on the following items:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. The election of seven directors for a term of one year;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. The ratification of the Company's appointment of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. The transaction of any other business that may properly come before the Annual Meeting or any adjournment of the Annual Meeting.

Only those stockholders of record as of the close of business on April 21, 2026 are entitled to vote at the Annual Meeting or any postponements or adjournments thereof. A complete list of stockholders entitled to vote at the Annual Meeting will be available for your inspection 10 days preceding our Annual Meeting, at our offices located at 1111 Kane Concourse, Suite 301, Bay Harbor Islands, FL 33154, between the hours of 10:00 a.m. and 5:00 p.m. ET, each business day, or if we determine that a physical in-person inspection is not practicable, such list of stockholders may be made available electronically, upon request.

#### YOUR VOTE IS IMPORTANT!
Instructions on how to vote your shares via the Internet are contained on the "Important Notice Regarding the Availability of Proxy Materials," which will be mailed on or about April 28, 2026. Instructions on how to obtain a paper copy of our proxy statement and annual report to stockholders for the year ended December 31, 2025 are listed on the "Important Notice Regarding the Availability of Proxy Materials." These materials can also be viewed online by following the instructions listed on the "Important Notice Regarding the Availability of Proxy Materials."

If you choose to receive a paper copy of our proxy statement and annual report, you may vote your shares by completing and returning the proxy card that will be enclosed.

[**Table of Contents**](#TOC)

Submitting your proxy does not affect your right to vote virtually if you decide to attend the Annual Meeting. You are urged to submit your proxy as soon as possible, regardless of whether or not you expect to attend the Annual Meeting. You may revoke your proxy at any time before it is voted at the Annual Meeting by (i) delivering written notice to our General Counsel and Corporate Secretary, Sam Berry, at our address above, (ii) submitting a later dated proxy card, (iii) voting again via the Internet as described in the "Important Notice Regarding the Availability of Proxy Materials," or (iv) attending the Annual Meeting and voting virtually. No revocation under (i) or (ii) will be effective unless written notice or the proxy card is received by our Corporate Secretary at or before the Annual Meeting.

When you submit your proxy, you authorize Lindsay A. Rosenwald, M.D. and David Jin to vote your shares at the Annual Meeting and on any adjournments of the Annual Meeting in accordance with your instructions.

---

| |
|:---|
| By Order of the Board of Directors, |
| /s/ Sam Berry |
| Sam Berry |
| *General Counsel and Corporate Secretary* |

---

April 28, 2026

Bay Harbor Islands, FL

[**Table of Contents**](#TOC)

#### FORTRESS BIOTECH, INC.
**1111 Kane Concourse, Suite 301**

**Bay Harbor Islands, FL**

**Phone: (781) 652-4500**

**Fax: (781) 459-7788**

#### PROXY STATEMENT
**This proxy statement is being made available via internet access, beginning on or about April 28, 2026, to the owners of shares of common stock of Fortress Biotech, Inc. (the "Company," "our," "we," or "Fortress") as of April 21, 2026, in connection with the solicitation of proxies by our Board of Directors for our 2026 Annual Meeting of Stockholders (the "Annual Meeting"). On or about April 28, 2026, we will send an "Important Notice Regarding the Availability of Proxy Materials" to our stockholders. If you receive this notice by mail, you will not automatically receive by mail our proxy statement and annual report to stockholders for the year ended December 31, 2025. If you would like to receive a printed copy of our proxy statement, annual report and proxy card, please follow the instructions for requesting such materials in the notice. Upon request, we will promptly mail you paper copies of such materials free of charge.**

The Annual Meeting will be held by live webcast on Wednesday, June 17, 2026 at 10:00 a.m. ET. You may access the meeting via the internet at www.virtualshareholdermeeting.com/fbio2026 when you enter your 16-digit control number included with the Internet Notice or proxy card. The virtual meeting platform is fully supported across browsers (Microsoft Edge, Firefox, Chrome, and Safari) and devices (desktops, laptops, tablets, and cell phones) running the most updated version of applicable software and plugins. You should ensure that you have a strong internet connection from wherever you intend to participate in the Annual Meeting. Our Board of Directors encourages you to read this document thoroughly and take this opportunity to vote, via proxy, on the matters to be decided at the Annual Meeting. As discussed below, you may revoke your proxy at any time before your shares are voted at the Annual Meeting.

[**Table of Contents**](#TOC)

#### **Table of Contents**

---

| | | |
|:---|:---|:---|
| [QUESTIONS AND ANSWERS](#QUESTIONSANDANSWERS_282065) | [QUESTIONS AND ANSWERS](#QUESTIONSANDANSWERS_282065) | 1 |
| [Q.](#QWhydidIreceiveanImportantNoticeRegardin) | [Why did I receive an "Important Notice Regarding the Availability of Proxy Materials"?](#QWhydidIreceiveanImportantNoticeRegardin) | 1 |
| [Q.](#QWhenistheAnnualMeeting_939449) | [When is the Annual Meeting?](#QWhenistheAnnualMeeting_939449) | 1 |
| [Q.](#QWherewilltheAnnualMeetingbeheld_827628) | [Where will the Annual Meeting be held?](#QWherewilltheAnnualMeetingbeheld_827628) | 1 |
| [Q.](#QWhatisthepurposeoftheAnnualMeeting_4842) | [What is the purpose of the Annual Meeting?](#QWhatisthepurposeoftheAnnualMeeting_4842) | 1 |
| [Q.](#QHowmanyvotesdoIhave_278254) | [How many votes do I have?](#QHowmanyvotesdoIhave_278254) | 1 |
| [Q.](#QWhoisentitledtovoteatourAnnualMeeting_7) | [Who is entitled to vote at our Annual Meeting?](#QWhoisentitledtovoteatourAnnualMeeting_7) | 2 |
| [Q.](#QHowdoIvote_649618) | [How do I vote?](#QHowdoIvote_649618) | 2 |
| [Q:](#QWhatifIhavetechnicaldifficultiesortroub) | [What if I have technical difficulties or trouble accessing the virtual Annual Meeting?](#QWhatifIhavetechnicaldifficultiesortroub) | 3 |
| [Q.](#QWhatisaproxy_254764) | [What is a proxy?](#QWhatisaproxy_254764) | 3 |
| [Q.](#QHowwillmysharesbevotedifIvotebyproxy_52) | [How will my shares be voted if I vote by proxy?](#QHowwillmysharesbevotedifIvotebyproxy_52) | 3 |
| [Q.](#QCanIchangemyvoteafterIreturnmyproxycard) | [Can I change my vote after I return my proxy card?](#QCanIchangemyvoteafterIreturnmyproxycard) | 3 |
| [Q.](#QIsmyvoteconfidential_799299) | [Is my vote confidential?](#QIsmyvoteconfidential_799299) | 4 |
| [Q.](#QHowarevotescounted_368317) | [How are votes counted?](#QHowarevotescounted_368317) | 4 |
| [Q.](#Whatistheeffectofabstentionsorbrokernonv) | [What is the effect of abstentions or broker non-votes?](#Whatistheeffectofabstentionsorbrokernonv) | 4 |
| [Q.](#QWhatconstitutesaquorumattheAnnualMeetin) | [What constitutes a quorum at the Annual Meeting?](#QWhatconstitutesaquorumattheAnnualMeetin) | 4 |
| [Q.](#QWhatvoteisrequiredtoelectourdirectorsfo) | [What vote is required to elect our directors for a one-year term?](#QWhatvoteisrequiredtoelectourdirectorsfo) | 5 |
| [Q.](#QWhatvoteisrequiredtoratifyKPMGLLPasouri) | [What vote is required to ratify KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026?](#QWhatvoteisrequiredtoratifyKPMGLLPasouri) | 5 |
| [Q.](#QWhatpercentageofouroutstandingcommonsto) | [What percentage of our outstanding common stock do our directors and executive officers own?](#QWhatpercentageofouroutstandingcommonsto) | 5 |
| [Q.](#QHowcanIfindouttheresultsofthevotingofth) | [How can I find out the results of the voting of the Annual Meeting?](#QHowcanIfindouttheresultsofthevotingofth) | 5 |
| [Q.](#QWhowasourindependentpublicaccountantfor) | [Who was our independent public accountant for the year ending December 31, 2025? Will they be represented at the Annual Meeting?](#QWhowasourindependentpublicaccountantfor)  | 5 |
| [Q.](#QWhoispayingforthisproxysolicitation_532) | [Who is paying for this proxy solicitation?](#QWhoispayingforthisproxysolicitation_532) | 6 |
| [Q.](#QHowcanIobtainacopyofourannualreportonFo) | [How can I obtain a copy of our annual report on Form 10-K?](#QHowcanIobtainacopyofourannualreportonFo) | 6 |
| [CORPORATE GOVERNANCE](#CORPORATEGOVERNANCE_217751) | [CORPORATE GOVERNANCE](#CORPORATEGOVERNANCE_217751) | 6 |
| [INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FEES AND OTHER MATTERS](#INDEPENDENTREGISTEREDPUBLICACCOUNTINGFIR) | [INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FEES AND OTHER MATTERS](#INDEPENDENTREGISTEREDPUBLICACCOUNTINGFIR) | 13 |
| [REPORT OF THE AUDIT COMMITTEE](#REPORTOFTHEAUDITCOMMITTEE4_795910) | [REPORT OF THE AUDIT COMMITTEE](#REPORTOFTHEAUDITCOMMITTEE4_795910) | 15 |
| [OUR EXECUTIVE OFFICERS](#OUREXECUTIVEOFFICERS_236525) | [OUR EXECUTIVE OFFICERS](#OUREXECUTIVEOFFICERS_236525) | 16 |

---

[**Table of Contents**](#TOC)

---

| | |
|:---|:---|
| [EXECUTIVE COMPENSATION](#EXECUTIVECOMPENSATION_654172) | 17 |
| [OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-END](#OUTSTANDINGEQUITYAWARDSAT2021FISCALYEARE) | 20 |
| [EQUITY COMPENSATION PLAN INFORMATION](#EQUITYCOMPENSATIONPLANINFORMATION_366293) | 22 |
| [PAY VERSUS PERFORMANCE](#PAYVERSUSPERFORMANCE) | 23 |
| [DIRECTOR COMPENSATION](#DIRECTORCOMPENSATION_815179) | 25 |
| [DELINQUENT SECTION 16(A) BENEFICIAL OWNERSHIP REPORTS](#DELINQUENTSECTION16ABENEFICIALOWNERSHIPR) | 27 |
| [RELATED-PERSON TRANSACTIONS](#RELATEDPERSONTRANSACTIONS_229002) | 27 |
| [STOCK OWNERSHIP OF OUR DIRECTORS, EXECUTIVE OFFICERS, AND 5% BENEFICIAL OWNERS](#STOCKOWNERSHIPOFOURDIRECTORSEXECUTIVEOFF) | 32 |
| [PROPOSAL ONE: ELECTION OF DIRECTORS; NOMINEES](#PROPOSALONEELECTIONOFDIRECTORSNOM) | 33 |
| [PROPOSAL TWO: RATIFICATION OF APPOINTMENT OF KPMG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM](#PROPOSALTWO_641918) | 34 |

---

[**Table of Contents**](#TOC)

#### QUESTIONS AND ANSWERS
Q.***Why did I receive an "Important Notice Regarding the Availability of Proxy Materials"?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. In accordance with Securities and Exchange Commission (the "SEC") rules, instead of mailing a printed copy of our proxy materials, we may send an "Important Notice Regarding the Availability of Proxy Materials" to stockholders. All stockholders will have the ability to access the proxy materials on the website referred to in the notice or to request a printed set of these materials at no charge. You will not receive a printed copy of the proxy materials unless you specifically request one from us. Instead, the notice instructs you as to how you may access and review all of the important information contained in the proxy materials via the internet and submit your vote via the internet.

Q.***When is the Annual Meeting?***

A.The Annual Meeting will be held at 10:00 a.m., ET, on Wednesday, June 17, 2026.

Q.***Where will the Annual Meeting be held?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. The Annual Meeting will be held virtually by means of a live webcast, as further described herein, which can be accessed at www.virtualshareholdermeeting.com/fbio2026 when you enter your 16-digit control number included with the Internet Notice or proxy card.

Q.***What is the purpose of the Annual Meeting?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. At the Annual Meeting, our stockholders will act upon the matters outlined in the Notice of Annual Meeting of Stockholders accompanying this proxy statement, including (i) electing seven directors for a term of one year, (ii) ratifying the appointment of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026, and (iii) transacting any other business that may properly come before the Annual Meeting or any adjournment thereof.

Q.***How many votes do I have?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. On each matter to be voted upon, you have one vote for each share of common stock you own as of the Record Date.

[**Table of Contents**](#TOC)

Q.***Who is entitled to vote at our Annual Meeting?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Only stockholders of record at the close of business on April 21, 2026, which we refer to as the Record Date, are entitled to receive notice of the Annual Meeting and to vote the shares that they held on that date at the Annual Meeting, or any adjournment or postponement thereof. As of the close of business on the Record Date, we had 33,219,072 shares of common stock outstanding. Each share of common stock entitles its holder to one vote at the Annual Meeting. A list of stockholders entitled to vote at the Annual Meeting may be examined at our offices located at 1111 Kane Concourse Suite 301 Bay Harbor Islands, FL 33154, between the hours of 10:00 a.m. and 5:00 p.m., ET, each business day, beginning 10 days preceding the Annual Meeting, or if we determine that a physical in-person inspection is not practicable, such list of stockholders may be made available electronically, upon request.

● *Stockholders of Record*: Shares Registered in Your Name. If on the Record Date your shares were registered directly in your name with our transfer agent, VStock Transfer, LLC, then you are a stockholder of record. As a stockholder of record, you may vote live during the Annual Meeting or vote by proxy. To do so, stockholders of record will need to visit www.virtualshareholdermeeting.com/fbio2026 and use their 16-digit Control Number provided in the Internet Notice to log in to this website. We encourage stockholders to log in to this website and access the webcast before the Annual Meeting's start time. Further instructions on how to attend, participate in and vote at the Annual Meeting, including how to demonstrate your ownership of our stock as of the record date, are available at www.virtualshareholdermeeting.com/fbio2026. Please note you will only be able to attend and vote in the meeting using this website. All references to attending the Annual Meeting "in person" in this proxy statement mean attending the live webcast at the Annual Meeting. Whether or not you plan to participate live during the Annual Meeting, we urge you to vote either by mail (if you requested a printed copy of these proxy materials to be mailed to you), via the internet or by telephone, as described in greater detail below, to ensure your vote is counted.

● *Beneficial Owner: Shares Registered in the Name of a Broker, Bank, Custodian or Other Nominee*. If on the Record Date your shares were held in an account at a brokerage firm, bank, custodian or other nominee, then you are a beneficial owner of shares held in "street name" and these proxy materials are being forwarded to you by that organization. The organization holding your account is considered the stockholder of record for purposes of voting at the Annual Meeting. As a beneficial owner, you have the right to direct your broker, bank, custodian or other nominee on how to vote the shares in your account. You are also invited to participate live in the Annual Meeting. To do so, you will need to follow the instructions provided by the bank, brokerage firm or other nominee that holds their shares.

Q.***How do I vote?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. You may vote during the Annual Meeting by following the instructions posted at www.proxyvote.com and entering your 16-digit control number included with the Internet Notice or proxy card, by use of a proxy card if you receive a printed copy of our proxy materials, or via Internet or by telephone as indicated in the proxy card or Internet Notice.

Whether you hold shares directly as the stockholder of record or indirectly as the beneficial owner of shares held for you by a broker or other nominee (i.e., in "street name"), you may direct your vote without attending the Annual Meeting. You may vote by granting a proxy or, for shares you hold in street name, by submitting voting instructions to your broker or nominee. In most instances, you will be able to do this by internet, telephone or by mail. Please refer to the summary instructions below and those included on your proxy card or, for shares you hold in street name, the voting instruction card provided by your broker or nominee.

●  ***By Internet*** — If you have Internet access, you may authorize your proxy from any location in the world as directed in our Internet Notice, proxy card (if you received a paper copy of our proxy materials) or, if applicable, the voting instructions that may be described on the voting instruction card sent to you by your bank, broker or other nominee.

[**Table of Contents**](#TOC)

●  ***By Telephone*** — If you are calling from the United States or Canada, you may authorize your proxy by following the "Vote by Phone" instructions on the Internet Notice, proxy card (if you received a paper copy of our proxy materials) or, if applicable, the telephone voting instructions that may be described on the voting instruction card sent to you by your bank, broker or other nominee.

●  ***By Mail*** — If you requested a printed copy of these proxy materials to be mailed to you, you may authorize your proxy by signing your proxy card and mailing it in the enclosed postage-prepaid and addressed envelope provided. For shares you hold in street name, you may sign the voting instruction card included by your broker or nominee and mail it in the envelope provided.

You may also vote live during the Annual Meeting by following the instructions posted at www.virtualshareholdermeeting.com/fbio2026 and entering your 16-digit control number included with the Internet Notice. If you choose to vote during the Annual Meeting, the virtual meeting platform is fully supported across browsers (Microsoft Edge, Firefox, Chrome, and Safari) and devices (desktops, laptops, tablets, and cell phones) running the most updated version of applicable software and plugins. You should ensure that you have a strong internet connection from wherever you intend to participate in the Annual Meeting.

Q.*What if I have technical difficulties or trouble accessing the virtual Annual Meeting?*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Our virtual platform provider will have technicians ready to assist you with any technical difficulties you may have accessing the virtual Annual Meeting. If you encounter any difficulties accessing the virtual Annual Meeting during the check-in or meeting time, please call the technical support number located on the meeting page.

Q.***What is a proxy?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. A proxy is a person you appoint to vote your shares on your behalf. If you are unable to attend the Annual Meeting, our Board of Directors is seeking your appointment of a proxy so that your shares may be voted. If you vote by proxy, you will be designating Lindsay A. Rosenwald, M.D., our Executive Chairman, Chief Executive Officer and President, and David Jin, our Chief Financial Officer, or either of them, as your proxies. In such event, Dr. Rosenwald and/or Mr. Jin may act on your behalf and have the authority to appoint a substitute to act as your proxy.

Q.***How will my shares be voted if I vote by proxy?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Your proxy will be voted according to the instructions you provide. If you complete and submit your proxy but do not otherwise provide instructions on how to vote your shares, your shares will be voted (i) "FOR" the individuals nominated to serve as members of our Board of Directors, and (ii) "FOR" the ratification of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026. Presently, our Board does not know of any other matter that may come before the Annual Meeting. However, your proxies are authorized to vote on your behalf, using their discretion, on any other business that properly comes before the Annual Meeting.

Q.***Can I change my vote after I return my proxy card?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Yes. You may revoke your proxy at any time before the final vote at the Annual Meeting in accordance with the following instructions:

If you are the record holder of your shares, you may revoke your proxy in any one of three ways:

● You may send a written notice that you are revoking your proxy to our General Counsel and Corporate Secretary, Sam Berry, at our address above (so long as we receive such notice no later than the close of business on the day before the Annual Meeting);

[**Table of Contents**](#TOC)

● You may submit a later-dated proxy card or vote again via the Internet or by telephone as described in the "Important Notice Regarding the Availability of Proxy Materials;" or

● You may attend the virtual Annual Meeting and notify the election officials at the Annual Meeting that you wish to revoke your proxy and vote live during the Annual Meeting by following the instructions posted at www.virtualshareholdermeeting.com/fbio2026 . Simply attending the Annual Meeting will not, by itself, revoke your proxy.

If your shares are held by your broker, bank, custodian or other nominee, you should follow the instructions provided by such broker, bank, custodian or other nominee.

Q.*Is my vote confidential?*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Yes. All votes remain confidential.

Q.***How are votes counted?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Before the Annual Meeting, our Board of Directors will appoint one or more inspectors of election for the meeting. The inspector(s) will determine the number of shares represented at the meeting, the existence of a quorum and the validity and effect of proxies. The inspector(s) will also receive, count, and tabulate ballots and votes and determine the results of the voting on each matter that comes before the Annual Meeting.

Q.***What is the effect of abstentions or broker non-votes?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. Abstentions will be treated as present for purposes of determining the existence of a quorum at the Annual Meeting. They will be considered as votes "against" any matter for which the minimum required vote for approval of that matter is (i) the affirmative vote of the majority of all outstanding shares or (ii) the affirmative vote of the majority of the shares present or represented at the meeting. They will not be considered as votes "for" or "against" any matter for which the minimum required vote for approval of that matter is the affirmative vote of a majority of the votes cast. Broker non-votes occur when shares are held indirectly through a broker, bank or other nominee or intermediary on behalf of a beneficial owner (referred to as held in "street name") and the broker submits a proxy, but does not cast a vote on a matter because the broker has not received voting instructions from the beneficial owner, and (i) the broker does not have discretionary voting authority on the matter or (ii) the broker chooses not to vote on a matter for which it has discretionary voting authority. Pursuant to the rules of the New York Stock Exchange ("NYSE"), which governs brokers' use of discretionary authority, brokers are permitted to exercise discretionary voting authority only on "routine" matters when voting instructions have not been timely received from a beneficial owner.

Only the ratification of the selection of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026 is considered a "routine" matter for which brokers, banks or other nominees may vote uninstructed shares. The other proposal to be voted on at the meeting, the annual election of our directors, is not considered "routine" under NYSE rules, so your broker, bank or other nominee cannot vote your shares on this proposal unless you provide to your broker, bank, or other nominee voting instructions for this matter. If you do not provide voting instructions on a non-routine matter, your shares will not be voted on that matter, which is a "broker non-vote."

Q.*What constitutes a quorum at the Annual Meeting?*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. In accordance with Delaware law (the law under which we are incorporated) and our Fourth Amended and Restated Bylaws, the presence at the Annual Meeting, by proxy or virtually in person, of the holders of a majority of the outstanding shares of the capital stock entitled to vote at the Annual Meeting constitutes a quorum, thereby permitting the stockholders to conduct business at the Annual Meeting. Abstentions, votes withheld, and shares held by brokers that are voted on any matter will be included in the calculation of the number of shares considered present at the Annual Meeting for purposes of determining the existence of a quorum. Broker-held shares that are not voted on any matter will not be included in determining whether a quorum is present.

[**Table of Contents**](#TOC)

If a quorum is not present at the Annual Meeting, then the Chairman shall have power to adjourn the meeting from time to time, without notice other than announcement at the meeting, until a quorum is present or represented. If an adjournment is for more than 30 days or a new record date is fixed for the adjourned meeting by our Board, we will provide notice of the adjourned meeting to each stockholder of record entitled to vote at the adjourned meeting. At any adjourned meeting at which a quorum is present, any business may be transacted that might have been transacted at the originally called Annual Meeting.

Q.*What vote is required to elect our directors for a one-year term?*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. At any meeting of our stockholders in which there is an uncontested director election, the affirmative vote of a majority of the shares of stock cast (meaning the number of shares voted "for" a nominee must exceed the number of shares voted "against" such nominee) by the holders of shares of our common stock present or represented at the Annual Meeting is required for the election of each of the nominees for director. Abstentions and broker non-votes will have no effect on the outcome of the vote. At any meeting of our stockholders in which there is a contested director election, a plurality of the votes cast by the holders of shares present in person or represented by proxy at the meeting and entitled to vote in the election directors is required for the election of each nominee for director. Presently, our Board does not know of any other nominees other than those selected by the Board. Accordingly, we expect that the director election will be uncontested.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***Q***.  ***What vote is required to ratify KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026?*** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***A.*** The affirmative vote of a majority of the shares of stock present or represented at the Annual Meeting is required to approve the ratification of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026. Abstentions will have the same effect as a negative vote. Because the ratification of KPMG LLP as our independent registered public accounting firm for the year ending December 31, 2026 is a "routine" proposal where brokers have discretionary authority to vote in the absence of instructions, we do not expect any broker non-votes.

Q.***What percentage of our outstanding common stock do our directors and executive officers own?***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. As of April 16, 2026, our directors and executive officers owned, or have the right to acquire, approximately 28.5 % of our outstanding common stock. See the discussion under the heading "Stock Ownership of Our Directors, Executive Officers, and 5% Beneficial Owners" on page 32 for more details.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***Q.***  ***How can I find out the results of the voting of the Annual Meeting?*** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. We will announce preliminary voting results at the Annual Meeting. We will also disclose voting results on a Form 8-K filed with the SEC, within four business days of the Annual Meeting.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***Q.***  ***Who was our independent public accountant for the year ending December 31, 2025? Will they be represented at the Annual Meeting?*** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. KPMG LLP was our independent public accountant for the year ended December 31, 2025, and we expect a representative of KPMG LLP to be present virtually at the Annual Meeting. The representative will have an opportunity to make a statement and will be available to answer your questions.

[**Table of Contents**](#TOC)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***Q.***  ***Who is paying for this proxy solicitation?*** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. We will pay the entire cost of preparing, assembling, printing, mailing, and distributing these proxy materials and soliciting votes. If you choose to vote over the internet, you are responsible for internet access charges you may incur. If you choose to vote by telephone, you are responsible for telephone charges you may incur. In addition to the mailing of these proxy materials, the solicitation of proxies or votes may be made in person, by telephone or by electronic communication by our directors, officers and employees, who will not receive any additional compensation for such solicitation activities, and also by our proxy solicitation firm who we have retained for that purpose, to whom we will pay a fee.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***Q.***  ***How can I obtain a copy of our annual report on Form 10-K?*** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. We have filed our annual report on Form 10-K for the year ended December 31, 2025, with the SEC. The annual report on Form 10-K is also available on the website referred to in the Internet Notice, in the "*Investors*" section of our website at *www.fortressbiotech.com*, and on the website of the SEC at *www.sec.gov*. You may obtain, free of charge, a copy of our annual report on Form 10-K, including financial statements and exhibits, by writing to our General Counsel and Corporate Secretary, Sam Berry, or by email at info@fortressbiotech.com. Upon request, we will also furnish any exhibits to the Annual Report on Form 10-K as filed with the SEC.

#### CORPORATE GOVERNANCE

#### Our Board of Directors
Our Fourth Amended and Restated Bylaws provide that the Board shall consist of no less than one (1) and no more than nine (9) members, as determined from time to time by resolution of the Board. Currently, our Board consists of seven (7) members, comprising our seven director nominees. The following individuals are being nominated to serve on our Board (See "Proposal 1 — Election of Directors; Nominees"):

---

| | | | |
|:---|:---|:---|:---|
| **Name of Director Nominee** | **Age** | **Title** | **Director Since** |
| Lindsay A. Rosenwald, M.D. | 71 | Chairman, President and Chief Executive Officer | October 2009 |
| Jimmie Harvey, Jr., M.D. | 74 | Director | December 2008 |
| Malcolm Hoenlein | 82 | Director | February 2014 |
| Dov Klein, CPA | 74 | Director | July 2015 |
| J. Jay Lobell | 63 | Director | June 2006 |
| Kevin L. Lorenz, J.D. | 61 | Director | August 2019 |
| Michael S. Weiss | 60 | Director and Executive Vice Chairman, Strategic Development | December 2013 |

---

The Board does not have a formal policy regarding the separation of the roles of Chief Executive Officer and Executive Chairman, as the Board believes that it is in the best interests of the Company to make that determination based on the direction of the Company and the current membership of the Board. The Board has determined that having a director who is an executive officer serve as the Chairman is in the best interest of the Company's stockholders at this time.

We have a risk management program overseen by both Lindsay A. Rosenwald, M.D., our Executive Chairman, Chief Executive Officer and President, and the Board. Dr. Rosenwald and management identify material risks and prioritize them for our Board. Our Board regularly reviews information regarding our credit, liquidity, operations, and compliance as well as the risks associated with each.

[**Table of Contents**](#TOC)

The following biographies set forth the names of our directors and director nominees, their ages, the year in which they first became directors, their positions with us, their principal occupations and employers for at least the past five years, any other directorships held by them during the past five years in companies that are subject to the reporting requirements of the Securities Exchange Act of 1934 (the "Exchange Act"), or any company registered as an investment company under the Investment Company Act of 1940, as well as additional information, all of which we believe sets forth each director nominee's qualifications to serve on the Board. None of our executive officers or directors is related to any of our other executive officers or directors by blood, marriage, or adoption. There are no arrangements or understandings between any of our executive officers or directors and any other person pursuant to which any of them are elected as an officer or director, except as disclosed below.

Fortress adheres to the corporate governance standards adopted by The Nasdaq Stock Market LLC ("Nasdaq"). Nasdaq rules require our Board to make an affirmative determination as to the independence of each director. Consistent with these rules, our Board completed its annual review of director independence on March 30, 2026. During the review, our Board considered relationships and transactions during 2025 and during the past three fiscal years between each director or any member of his or her immediate family, on the one hand, and the Company and our partner companies and affiliates, on the other hand. The purpose of this review was to determine whether any such relationships or transactions were inconsistent with a determination that the director is independent. Based on this review, our Board determined that Dr. Harvey and Messrs. Hoenlein, Klein, Lobell, and Lorenz are independent under the criteria established by Nasdaq and our Board.

#### Director Nominees
***Lindsay A. Rosenwald, M.D.*** has served as a member of the Company's Board of Directors since October 2009 and as Chairman, President and Chief Executive Officer of the Company since December 2013. Dr. Rosenwald also currently serves as a member of the board of directors of Fortress partner companies Mustang Bio, Inc. (Nasdaq: MBIO) ("Mustang"), Journey Medical Corporation (Nasdaq: DERM) ("Journey") and Avenue Therapeutics, Inc. (OTCID: ATXI) ("Avenue"). Additionally, Dr. Rosenwald serves as a member of the board of directors of each of Fortress' private subsidiaries (and has so served in each case since company inception). From 1991 to 2008, Dr. Rosenwald served as the Chairman of Paramount BioCapital, Inc. Over the past 30 years, Dr. Rosenwald has acted as a biotechnology entrepreneur and has been involved in the founding, recapitalization and sale of numerous public and private biotechnology and life science companies. He received his B.S. in finance from Pennsylvania State University and his M.D. from Temple University School of Medicine. Based on Dr. Rosenwald's biotechnology and pharmaceutical industry experience, medical expertise, financial aptitude and decades of management experience, the Board of Directors believes that Dr. Rosenwald has the appropriate set of skills to serve as a member of the Board in light of the Company's business and structure.

***Jimmie Harvey, Jr., M.D.*** has served as a member of the Board of Directors since December 2008. In 1984, Dr. Harvey founded Birmingham Hematology and Oncology Associates, L.L.C. (now Alabama Oncology, L.L.C.), a private medical company located in Birmingham, Alabama. Dr. Harvey served as President of Alabama Oncology, LLC until 2020. Dr. Harvey has experience in clinical trial execution and management and was a principal investigator in two trials, one investigating a novel monoclonal antibody and the other investigating a small molecule used to treat immunologic malignancies. Dr. Harvey holds a B.A. in chemistry from Emory University and received his M.D. from Emory University School of Medicine. Dr. Harvey completed his medical oncology training at the Vincent T. Lombardi Cancer Center at Georgetown University. Based on Dr. Harvey's medical background, including his oncology expertise, the Board of Directors believes that Dr. Harvey has the appropriate set of skills to serve as a member of the Board in light of the Company's business and structure.

[**Table of Contents**](#TOC)

***Malcolm Hoenlein*** has served as a member of the Board of Directors since February 2014. From 1986 to 2021, Mr. Hoenlein served as Executive Vice Chairman of the Conference of Presidents of Major American Jewish Organizations, the coordinating body on international and national concerns for 51 national American Jewish organizations and since 2021 continues as Vice Chairman Emeritus. Previously, he served as the founding Executive Director of the Jewish Community Relations Council of Greater New York. Prior to that, he was the founding Executive Director of the New York Conference on Soviet Jewry. A National Defense Fellow at the Near East Center of the University of Pennsylvania, Mr. Hoenlein taught International Relations in the Political Science Department and served as a Middle East specialist at the Foreign Policy Research Institute. In addition, he served on the editorial staff of ORBIS, the Journal of World Affairs. He serves currently as a director of Nanox Imaging Plc. and Bonus BioGroup. He previously served as a director for DarioHealth Corp, WellSense Technology, Delek Oil, Eco-Fusion North America, Inc., Powermat USA, and Bank Leumi USA. Mr. Hoenlein has a B.A. in Political Science from Temple University and an M.A. in International Relations from the University of Pennsylvania, as well as an Hon. LL.D. from Touro College, an Hon. D.H.L. from Yeshiva University, an Hon. D.H.L. from Temple University and an Hon. D.H.L. from Bar Ilan University. Based on Mr. Hoenlein's demonstrated sound business judgment and leadership and management experience, the Board of Directors believes that Mr. Hoenlein has the appropriate set of skills to serve as a member of the Board in light of the Company's business and structure.

***Dov Klein, CPA*** has served as a member of the Board of Directors since July 2015. From January 2016 through December 31, 2020, Mr. Klein was an audit partner at Marks Paneth LLP, a certified public accounting and consulting firm. Effective January 1, 2021, Mr. Klein is a retired partner of Marks Paneth LLP. Prior to 2016, Mr. Klein was an audit partner at RSSM CPA LLP, a certified public accounting and strategic advisory firm, which he joined in 2001. His practice focused on audits and reviews and compilation of financial statements for clients in various industries. Mr. Klein has also consulted on matters in litigation and conducted financial due diligence in mergers and acquisitions as well as business planning for growing businesses. Mr. Klein has been a certified public accountant since 1978 and is a member of the American Institute of Certified Public Accountants and the New York State Society of Certified Public Accountants. Mr. Klein received his BSc in Accounting from Brooklyn College, The City University of New York. Based on Mr. Klein's extensive business experience, particularly in the areas of audit and finance, the Board of Directors believes that Mr. Klein has the appropriate set of skills and experience to serve as a member of the Board in light of the Company's business and structure.

***J. Jay Lobell*** has served as a member of the Board of Directors since June 2006. Mr. Lobell is President of GMF Capital, LLC which he co-founded in January 2016. Mr. Lobell was also a founder of Beech Street Capital, LLC, a real estate lending company, serving as its Vice Chairman from December 2009 until the company's sale to Capital One Financial Corporation in November 2013. From January 2005 to December 2009, Mr. Lobell served as President and Chief Operating Officer of Paramount Biosciences, LLC, or PBS, a private biotechnology investment and development company. In that capacity, he had substantial responsibility for the assembly and oversight of companies PBS founded and incubated, including the Company. Mr. Lobell currently serves on the board of directors of several private companies, including Sava Senior Care, where he has served since September 2013, Tender Touch Rehabilitation Services, where he has served since October 2014, and Pardes Biosciences, where he has served since January 2021. Mr. Lobell was a partner in the law firm Covington & Burling LLP from October 1996 through January 2005, where he advised companies and individuals as a member of the firm's securities litigation and white collar defense practice group. Mr. Lobell received his B.A. (summa cum laude, Phi Beta Kappa) from The City University of New York and his J.D. from Yale Law School, where he was senior editor of The Yale Law Journal. Based on Mr. Lobell's biotechnology, legal and financial experience, as well as his substantial understanding of drug development and corporate governance, the Board of Directors believes that Mr. Lobell has the appropriate set of skills and experience to serve as a member of the Board in light of the Company's business and structure.

[**Table of Contents**](#TOC)

***Kevin L. Lorenz, J.D***. has served as a member of the Board of Directors since August 2019. Mr. Lorenz has over 25 years of experience guiding and implementing investment strategies across public and private companies. Since 2021, Mr. Lorenz has served as a Director at Adventus Capital Partners. Since 2015, Mr. Lorenz has been Chief Investment Officer, Senior Vice President, Treasury & Private Investments at the Katz Group in the family office of Daryl Katz, which has operations in sports and entertainment, real estate, and public and private investments. Mr. Lorenz works directly with the principal of the Katz Group to oversee the design, implementation, and monitoring of the overall investment strategy for public and private passive investments. Prior to joining the Katz Group, Mr. Lorenz was Director, Ultra High Net Worth ("UHNW") Private Client Business at Credit Suisse Securities, LLC from 2009 - 2015, where he was selected to expand Credit Suisse's UHNW private client business into Canada. From 2004 to 2009, Mr. Lorenz was the Director, UHNW Management Group at UBS Financial Services, Inc., where he was a key contributor to the formation and development of the company's first dedicated UBS UHNW office. Earlier in his career, he held positions of increasing responsibility at Merrill Lynch Pierce Fenner & Smith, Inc. and the Office of the Comptroller of the Currency, an independent bureau within the U.S. Department of the Treasury that charters, regulates and supervises all national banks and thrift institutions. Mr. Lorenz holds a J.D. from George Mason University Antonin Scalia Law School, an M.B.A. from Benedictine University and a B.S. in economics from Illinois State University. Based on Mr. Lorenz's extensive business, financials, and investment experience, the Board of Directors believes that Mr. Lorenz has the appropriate set of skills and experience to serve as a member of the Board in light of the Company's business and structure.

***Michael S. Weiss*** has served as our Executive Vice Chairman, Strategic Development since February 2014. He currently serves as a member of the board of directors of Mustang Bio, Inc. (Nasdaq: MBIO), one of our partner companies. Since December 2011, Mr. Weiss has served in multiple capacities at TG Therapeutics, Inc. (Nasdaq: TGTX), a related party, and is currently its Executive Chairman, Chief Executive Officer and President. In 1999, Mr. Weiss founded Access Oncology, which was later acquired by Keryx Biopharmaceuticals (Nasdaq: KERX) in 2004. Following the merger, Mr. Weiss remained as CEO of Keryx. He began his professional career as a lawyer with Cravath, Swaine & Moore LLP. Mr. Weiss earned his B.S. in Finance from The University of Albany and his J.D. from Columbia Law School. Based on Mr. Weiss's extensive biotechnology and pharmaceutical industry experience, as well as his relevant legal and management expertise, the Board of Directors believes that Mr. Weiss has the appropriate set of skills and experience to serve as a member of the Board in light of the Company's business and structure.

During 2025, our Board held five meetings, and each of our incumbent directors attended or participated telephonically in 75% or more of the aggregate of (a) the total number of meetings of the Board held during the period for which he served as a director and (b) the total number of meetings of all committees on which the director served during the periods that he served. The permanent committees established by our Board of Directors are the Audit Committee, the Compensation Committee and the Nominating and Corporate Governance Committee, descriptions of which are set forth in more detail below. Our directors are expected to attend each Annual Meeting of Stockholders, and it is our expectation that all of the directors standing for election will attend this year's Annual Meeting. Last year, four of our then-incumbent directors attended the 2025 Annual Meeting of Stockholders.

#### Communicating with the Board of Directors
Our Board has established a process by which stockholders can send communications to the Board. You may communicate with the Board as a group, or to specific directors, by writing to our General Counsel and Corporate Secretary, Sam Berry, at our offices located at 1111 Kane Concourse, Suite 301, Bay Harbor Islands, FL 33154. The General Counsel and Corporate Secretary will review all such correspondence and regularly forward to the Board a summary of all correspondence and copies of all correspondence that deals with the functions of the Board or committees thereof or that otherwise requires their attention. Directors may at any time review a log of all correspondence we receive that is addressed to members of our Board and request copies of any such correspondence. Concerns relating to accounting, internal controls, or auditing matters may be communicated in this manner, or may be submitted on an anonymous basis via e-mail at *info@fortressbiotech.com*. These concerns will be immediately brought to the attention of our Audit Committee and resolved in accordance with procedures established by our Audit Committee.

[**Table of Contents**](#TOC)

#### Audit Committee
The Audit Committee currently consists of Messrs. Klein (chair) and Lobell, and Dr. Harvey. During 2025, the Audit Committee held four meetings and separately took action by unanimous written consent one time. The duties and responsibilities of the Audit Committee are set forth in the Charter of the Audit Committee which was recently reviewed by our Audit Committee. Our Audit Committee determined that no revisions needed to be made to the charter at this time. A copy of the Charter of the Audit Committee is available on our website, located at www.fortressbiotech.com, under the Investors – Governance – Governance Documents section. Our Audit Committee has sole discretion over the retention, compensation, evaluation and oversight of our independent registered public accounting firm. Among other matters, the duties and responsibilities of the Audit Committee include:

● reviewing and monitoring our financial statements and internal accounting procedures;

● selecting of our independent registered public accounting firm and consulting with and reviewing the services provided by our independent registered public accounting firm.

● assisting the Board in overseeing the Company's processes for identifying and managing major financial risk exposures and the Company's risk assessment and risk management policies;

● overseeing procedures for the receipt, retention and treatment of complaints regarding accounting, internal controls, or auditing matters, including confidential and anonymous submissions by employees; and

● overseeing the Company's compliance with legal and regulatory requirements and monitors compliance with the Company's Code of Business Conduct and Ethics (including reviewing any material violations or waivers).

The SEC and Nasdaq have established rules and regulations regarding the composition of audit committees and the qualifications of audit committee members. Our Board of Directors has examined the composition of our Audit Committee and the qualifications of our Audit Committee members in light of the current rules and regulations governing audit committees. Based upon this examination, our Board of Directors has determined that each member of our Audit Committee is independent and is otherwise qualified to be a member of our Audit Committee in accordance with the rules of the SEC and Nasdaq.

Additionally, the SEC requires that at least one member of the Audit Committee have a "heightened" level of financial and accounting sophistication. Such a person is known as the "audit committee financial expert" under the SEC's rules. Our Board has determined that Mr. Klein is an "audit committee financial expert," as the SEC defines that term, and is an independent member of our Board of Directors and our Audit Committee. Please see Mr. Klein's biography above for a description of his relevant experience.

The report of the Audit Committee can be found on page 15 of this proxy statement.

[**Table of Contents**](#TOC)

#### Compensation Committee
The Compensation Committee held one meeting, and separately took action by unanimous written consent one time, during 2025. The Compensation Committee currently consists of Messrs. Lobell (chair) and Klein, and Dr. Harvey. The duties and responsibilities of the Compensation Committee are set forth in its charter. A copy of the charter of the Compensation Committee is available on the Company's website, located at www.fortressbiotech.com, under the Investors — Governance — Governance Documents section. As discussed in its charter, among other things, the duties and responsibilities of the Compensation Committee include annually evaluating the performance of the Chief Executive Officer and our other executive officers, determining the overall compensation of the Chief Executive Officer and our other executive officers and administering all executive compensation programs, including, but not limited to, our incentive and equity-based plans. In addition to executive compensation, the Compensation Committee also annually reviews and makes recommendations to the Board of Directors with respect to non-executive officer and director compensation. The Compensation Committee also reviews and discusses with management the compensation disclosures in our proxy statement and reviews and approves the say on pay and frequency proposals to be periodically included in our proxy statement. The results of such say-on-pay vote are taken into account by the Compensation Committee, as required by Section 14A of the Exchange Act, in determining executive compensation. The Compensation Committee applies discretion in the determination of individual executive compensation packages to ensure compliance with the Company's compensation philosophy. The Chief Executive Officer makes recommendations to the Compensation Committee with respect to the compensation packages for officers other than himself. The Compensation Committee may delegate its authority to grant awards to certain employees, and within specified parameters under the Compensation Committee Charter, to a special committee consisting of one or more directors who may but need not be officers of the Company. The Compensation Committee periodically reviews the Company's compensation policies and practices to evaluate whether they encourage excessive risk-taking and to align them with the Company's risk management and governance objectives. The Compensation Committee has authority to retain and terminate compensation consultants, legal counsel and other advisors, approve their fees, and consider their independence and any conflicts of interest in accordance with applicable SEC and Nasdaq requirements.

Nasdaq has established rules and regulations regarding the composition of compensation committees and the qualifications of compensation committee members. Our Board of Directors has examined the composition of our Compensation Committee and the qualifications of our Compensation Committee members in light of the current rules and regulations governing compensation committees. Based upon this examination, our Board of Directors has determined that each member of our Compensation Committee is independent and is otherwise qualified to be a member of our Compensation Committee in accordance with such rules.

Additional information regarding the Compensation Committee's processes and procedures for consideration of executive compensation can be found in the "Executive Compensation" section beginning on page 17 of this proxy statement.

#### Nominating and Corporate Governance Committee
The Nominating and Corporate Governance Committee is currently composed of Messrs. Lobell (chair), Hoenlein and Klein. The Nominating and Corporate Governance Committee held no meetings during 2025, and there were no actions taken by unanimous written consent on a standalone basis by the committee during 2025. The functions of the Nominating and Corporate Governance Committee include, among other things:

● making recommendations to the Board of Directors regarding the size and composition of the Board of Directors;

● developing minimum qualifications for director candidates and evaluating such candidates in such a manner as the Nominating and Corporate Governance Committee deems appropriate;

● except where otherwise required, selecting candidates for election to the Board of Directors and to fill any vacancies on the Board of Directors, such selected candidates to then be voted by the Board of Directors;

● establishing procedures for the nomination process;

● establishing and administering periodic assessment procedures relating to the performance of the Board of Directors as a whole and its individual members; and

[**Table of Contents**](#TOC)

● making recommendations to the Board of Directors regarding corporate governance matters and practices, including formulating and periodically reviewing corporate governance guidelines to be adopted by the Board of Directors.

The Nominating and Corporate Governance Committee of the Board of Directors is responsible for establishing the qualifications for director candidates. The Committee does not have a formal policy on Board of Directors candidate qualifications. It may consider those factors it deems appropriate in evaluating director nominees made either by the Board of Directors or stockholders, including judgment, skill, strength of character, experience with businesses and organizations comparable in size or scope to the Company, experience and skills relative to other Board of Directors' members, specialized knowledge or experience, and diversity. Depending upon the current needs of the Board of Directors, certain factors may be weighed more or less heavily than others. In considering candidates for the Board of Directors, the directors evaluate the entirety of each candidate's credentials and do not currently have any specific minimum qualifications that must be met. The directors will consider candidates from any reasonable source, including current Board of Directors' members, stockholders, professional search firms or other persons. The directors will not evaluate candidates differently based on who made the recommendation. Our policy describing our director nomination process is included in our Nominating and Corporate Governance Committee Charter, which is available on the Company's website, located at www.fortressbiotech.com, under the Investors — Governance — Governance Documents section. We believe that the current process in place functions effectively to select director nominees who will be valuable members of our Board of Directors. We identify potential nominees to serve as directors through a variety of business contacts, including current executive officers, directors, community leaders and stockholders. We may, to the extent appropriate, retain a professional search firm or other advisors to identify potential nominees.

We will also consider candidates recommended by stockholders for nomination to our Board. A stockholder who wishes to recommend a candidate for nomination to our Board must submit such recommendation to our General Counsel and Corporate Secretary, Sam Berry, at our offices located at 1111 Kane Concourse, Suite 301, Bay Harbor Islands, FL 33154. Any recommendation must be received not less than 45 calendar days nor more than 75 calendar days before the anniversary date of the previous year's annual meeting. All stockholder recommendations of candidates for nomination for election to our Board must be in writing and must set forth the following: (i) the candidate's name, age, business address, and other contact information, (ii) the number of shares of common stock beneficially owned by the candidate, (iii) the date or dates such shares were acquired and the investment intent of such acquisition, (iv) a complete description of the candidate's qualifications, experience, background and affiliations, as would be required to be disclosed in the proxy statement pursuant to Schedule 14A under the Exchange Act, (v) a written statement by the candidate in which he or she consents to being named in the proxy statement as a nominee and to serve as director if elected, and (vi) the name and address of the stockholder(s) of record making such a recommendation.

We believe that our Board as a whole should encompass a range of talent, skill, and expertise enabling it to provide sound guidance with respect to our operations and interests. Our independent directors evaluate all director candidates by reviewing their biographical information and qualifications. If the independent directors determine that a candidate is qualified to serve on our Board, such candidate is interviewed by at least one of the independent directors and our Chief Executive Officer. Other members of the Board also have an opportunity to interview qualified candidates. The independent directors then determine, based on the background information and the information obtained in the interviews, whether to recommend to the Board that the candidate be nominated for approval by the stockholders to fill a directorship. With respect to an incumbent director whom the independent directors are considering as a potential nominee for re-election, the independent directors review and consider the incumbent director's service during his or her term, including the number of meetings attended, level of participation, and overall contribution to the Board. The manner in which the independent directors evaluate a potential nominee does not differ based on whether the candidate is recommended by our directors or stockholders.

[**Table of Contents**](#TOC)

We consider the following qualifications, among others, when making a determination as to whether a person should be nominated to our Board: the independence of the director nominee; the director nominee's character and integrity; financial literacy; level of education and business experience, including experience relating to biopharmaceutical companies; whether the director nominee has sufficient time to devote to our Board; and the director nominee's commitment to represent the long-term interests of our stockholders. We review candidates in the context of the current composition of the Board and the evolving needs of our business. We believe that each of the current members of our Board (all of whom are director nominees) has the requisite business, biopharmaceutical, financial or managerial experience to serve as a member of the Board, as described above in their biographies under the heading "Our Board of Directors." We also believe that each of the current members of our Board has other key attributes that are important to an effective board, including integrity, high ethical standards, sound judgment, analytical skills, and the commitment to devote significant time and energy to service on the Board and its committees.

#### Code of Business Conduct and Ethics
We have adopted the Code of Business Conduct and Ethics, or the Code, which applies to all of our directors, officers and employees, including our principal executive officer and principal financial officer. The Code includes guidelines dealing with the ethical handling of conflicts of interest, compliance with federal and state laws, financial reporting, and our proprietary information. The Code also contains procedures for dealing with and reporting violations of the Code. We have posted our Code of Business Conduct and Ethics under the Investors — Governance — Governance Documents section of the Company's website, located at www.fortressbiotech.com. Any changes to or waivers of the Code of Ethics will be posted at that website.

#### Insider Trading Policy Prohibiting Hedging and Speculative Trading
We maintain an insider trading policy ("Insider Trading Policy") that governs the purchase, sale and other dispositions of our securities by the Company, directors, officers and employees. Our Insider Trading Policy is designed to promote compliance with insider trading laws, rules and regulations and any applicable listing standards. Additionally, pursuant to our Insider Trading Policy, our officers, directors, and employees are prohibited from engaging in speculative trading, including hedging transactions or short sale transactions with respect to Company securities.

#### INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FEES AND OTHER MATTERS
KPMG LLP ("KPMG") has served as the Company's independent registered public accounting firm since September 28, 2021. We expect a representative of KPMG to be present at the Annual Meeting. The representative will have an opportunity to make a statement, if he or she desires to do so, and will be available to answer your questions.

Our Board has asked the stockholders to ratify the selection of KPMG as our independent registered public accounting firm. See "Proposal Two: Ratification of Appointment of KPMG as Our Independent Registered Public Accounting Firm" on page 34 of this proxy statement. The Board has reviewed the fees described below and concluded that the payment of such fees is compatible with maintaining KPMG's independence.

All proposed engagements of KPMG, whether for audit services, audit-related services, tax services, or permissible non-audit services, were pre-approved by our Audit Committee.

#### Audit Fees
For the fiscal year ended December 31, 2025, we were billed approximately $2,995,470 by KPMG in fees for the professional services rendered in connection with the audits of our annual financial statements included in our Annual Report on Form 10-K for the 2025 fiscal year, the review of our financial statements included in our Quarterly Reports on Form 10-Q for 2025, and other services provided in connection with registration statements. In 2025, included in these fees for KPMG is $2,091,570 related to stand-alone audits and filings of certain of the Company's partner companies and subsidiaries.

[**Table of Contents**](#TOC)

For the fiscal year ended December 31, 2024, we were billed approximately $3,785,420 by KPMG in fees for the professional services rendered in connection with the audits of our annual financial statements included in our Annual Report on Form 10-K for the 2024 fiscal year, the review of our financial statements included in our Quarterly Reports on Form 10-Q for 2024, and other services provided in connection with registration statements. In 2024, included in these fees for KPMG is $2,756,520 related to stand-alone audits and filings of certain of the Company's partner companies and subsidiaries.

#### Audit-Related Fees
During the fiscal years ended December 31, 2025 and 2024, we incurred no costs from KPMG for audit-related services reasonably related to the performance of the audits and reviews for the respective fiscal years.

**Tax Fees**

During the fiscal years ended December 31, 2025 and 2024, we were billed approximately $52,333 and $55,229, respectively, from KPMG for fees for professional services rendered for tax compliance, tax advice, and tax planning services for certain of the Company's partner companies.

#### All Other Fees
During the fiscal years ended December 31, 2025 and 2024, we incurred no costs from KPMG for other accounting fees not related directly to the audit for the respective fiscal years. During the fiscal year ended December 31, 2024, certain of the Company's partner companies and subsidiaries incurred $25,000 from BDO USA, LLP for other accounting fees not directly related to the audit for the respective fiscal year.

#### Pre-Approval of Services
Our Audit Committee has established a policy setting forth the procedures under which services provided by our independent registered public accounting firm will be pre-approved by our Audit Committee. The potential services that might be provided by our independent registered public accounting firm fall into two categories:

● Services that are permitted, including the audit of our annual financial statements, the review of our quarterly financial statements, comfort letters, related attestations, benefit plan audits and similar audit reports, financial and other due diligence on acquisitions, and federal, state, and non-US tax services;

● Services that may be permitted, subject to individual pre-approval, including compliance and internal-control reviews, indirect tax services such as transfer pricing and customs and duties, and forensic auditing; and

● Services that our independent registered public accounting firm may not provide include such services as bookkeeping, certain human resources services, internal audit outsourcing, and investment or investment banking advice.

All proposed engagements of our independent registered public accounting firm, whether for audit services or permissible non-audit services, are pre-approved by the Audit Committee. We jointly prepare a schedule with our independent registered public accounting firm that outlines services which we reasonably expect we will need from our independent registered public accounting firm and categorize them according to the classifications described above. Each service identified is reviewed and approved or rejected by the Audit Committee.

[**Table of Contents**](#TOC)

#### REPORT OF THE AUDIT COMMITTEE
In monitoring the preparation of our financial statements, the Audit Committee met with management and representatives of KPMG LLP, the Company's independent registered public accounting firm for the fiscal year ended December 31, 2025, to review and discuss all financial statements prior to their issuance and to discuss any and all significant accounting issues. Management and our independent registered public accounting firm advised the Audit Committee that all of the financial statements were prepared in accordance with generally accepted accounting principles. The Audit Committee's review included a discussion of the matters required to be discussed pursuant to Public Company Accounting Oversight Board (United States) Auditing Standard 1301 (Communication with Audit Committees). Auditing Standard 1301 requires our independent registered public accounting firm to discuss with the Audit Committee, among other things, the following:

● Methods used to account for significant or unusual transactions;

● The effect of any accounting policies in controversial or emerging areas for which there is a lack of authoritative guidance or consensus;

● The process used by management to formulate sensitive accounting estimates and the basis for the independent registered public accounting firm's conclusion regarding the reasonableness of any such estimates; and

● Any disagreements with management over the application of accounting principles, the basis for management's accounting estimates and the disclosures necessary in the financial statements.

The Audit Committee has discussed the independence of KPMG LLP for the fiscal year ended December 31, 2025, including the written disclosures made by KPMG LLP to the Audit Committee, as required by PCAOB Rule 3526, "Communication with Audit Committees Concerning Independence." PCAOB Rule 3526 requires the independent registered public accounting firm to (i) disclose in writing all relationships that, in the independent registered public accounting firm's professional opinion, may reasonably be thought to bear on independence, (ii) confirm their perceived independence, and (iii) engage in a discussion of independence with the Audit Committee.

Finally, the Audit Committee continues to monitor the scope and adequacy of our internal controls and other procedures, including any and all proposals for adequate staffing and for strengthening internal procedures and controls where appropriate and necessary. These measures include, without limitation, a quarterly review of related party transactions and relationships pursuant to regularly-updated reports prepared by the Company's internal legal counsel and Chief Financial Officer.

On the basis of these reviews and discussions, the Audit Committee recommended to the Board that it approve the inclusion of our audited financial statements in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025, for filing with the SEC.

By the Audit Committee of the Board of Directors,

Dov Klein, CPA, Chairman

Jimmie Harvey, Jr., M.D.

J. Jay Lobell

Dated April 28, 2026

[**Table of Contents**](#TOC)

#### OUR EXECUTIVE OFFICERS

#### Executive Officers
Our current executive officers are as follows:

---

| | | |
|:---|:---|:---|
| **Name** | **Age** | **Position** |
| Lindsay A. Rosenwald, M.D. | 71 | Executive Chairman, Chief Executive Officer and President |
| David Jin | 36 | Chief Financial Officer and Head of Corporate Development |
| Michael S. Weiss | 60 | Executive Vice Chairman, Strategic Development |

---

No executive officer is related by blood, marriage or adoption to any other director or executive officer. The biographies of Dr. Rosenwald and Mr. Weiss are presented in connection with "Corporate Governance" beginning on page 6 of this proxy statement.

***David Jin*** has served as our Chief Financial Officer since August 2022 and as Head of Corporate Development since May 2020. He also serves on the board of directors of Mustang (Nasdaq: MBIO) and as Interim Chief Financial Officer and Chief Operating Officer of Avenue (OTCID: ATXI) (both Fortress partner companies). He also serves on the board of Crystalys Therapeutics. Previously, he was on the investment team in the Private Equity & Real Assets group at Barings, Director of Corporate Development at Sorrento Therapeutics, Vice President of Healthcare Investment Banking at FBR & Co., and was in the management consulting group at IMS Health (now IQVIA). He holds a B.S. in Industrial Engineering & Management Sciences with a double-major in Mathematical Methods in the Social Sciences from Northwestern University.

[**Table of Contents**](#TOC)

#### EXECUTIVE COMPENSATION
**Summary Compensation Table**

As determined in accordance with SEC rules, our "named executive officers" for purposes of this proxy statement are the three individuals set forth below. The following table sets forth information concerning compensation paid by the Company and its consolidated subsidiaries to its named executive officers for services rendered to it in all capacities during the years ended December 31, 2025, and December 31, 2024. In cases where a subsidiary of the Company is subject to SEC periodic reporting requirements and a named executive officer of the Company also serves as a director or named executive officer of that subsidiary, compensation paid by the subsidiary to our named executive officers will appear both in the table below and in the SEC disclosures of the subsidiary.

**Fortress Biotech, Inc. and Consolidated Subsidiaries**

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| <br>**Name and principal position(s)** | <br>**Year** | <br>**Salary**<br>**($)** | <br>**Bonus**<br>**($)** | <br>**Stock**<br>**Awards**<sup>(1)</sup><br>**($)** | <br>**Option**<br>**Awards**<sup>(1)</sup><br>**($)** | **All**<br>**Other**<br>**Compensation**<sup>(2)</sup><br>**($)** | <br>**Total**<br>**($)** |
| Lindsay A. Rosenwald, M.D. |  |  |  |  |  |  |  |
| Chairman, President and | 2025 | $62665 | 500000<br><sup>(3)</sup> | $2199592 | $— | $125000 | $2887256 |
| Chief Executive Officer | 2024 | 62665 |  | 1103032 | 64500 | 150000 | 1380197 |
| David Jin |  |  |  |  |  |  |  |
| Chief Financial Officer and | 2025 | 427875 | 172200<br><sup>(3)</sup> |  |  | 64000 | 664075 |
| Head of Corporate Development  | 2024 | 420000 | 218400<br><sup>(4)</sup> | 1899900 |  | 26967<br><sup>(5)</sup> | 2565267 |
| Michael S. Weiss |  |  |  |  |  |  |  |
| Executive Vice Chairman, | 2025 | 62665 | 500000<br><sup>(3)</sup> | 1789096 |  | 90000 | 2441762 |
| Strategic Development | 2024 | 62665 |  | 1047680 |  | 120000 | 1230345 |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Represents the aggregate grant date fair value of equity-based awards granted by the Company and its consolidated subsidiaries, computed in accordance with FASB Accounting Standards Codification Topic 718, Stock Compensation, as modified or supplemented ("FASB ASC Topic 718"), using the assumptions set forth in Note 13 to the audited financial statements in the Company's Annual Report on Form 10-K for the year ended December 31, 2025. In accordance with the terms of the LTIP (as defined below), Dr. Rosenwald and Mr. Weiss were each awarded 475,163 shares of restricted common stock of the Company (equal to one percent (1%) of the total outstanding shares of the Company as of the grant date) for their performance in 2025. Furthermore, Dr. Rosenwald and Mr. Weiss were each awarded 12,195 shares of restricted Checkpoint common stock for their roles on the board of directors for the year ended December 31, 2025, which awards vested in full in 2025 in connection with Checkpoint's merger with Sun Pharmaceuticals Industries Limited. Additionally, Dr. Rosenwald received 57,173 restricted stock units of Journey common stock for his role on the board of directors for the year ended December 31, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;(2) All Other Compensation for 2025 for Dr. Rosenwald comprises $50,000 in cash fees from each of Mustang and Journey and $25,000 from Checkpoint Therapeutics, Inc. ("Checkpoint") for his service on the Boards of Directors of those companies for the year ended December 31, 2025. All Other Compensation for 2025 for Mr. Weiss, in each case to an LLC wholly-owned by Mr. Weiss, comprises $30,000 cash fees received for his service as Chairman of the Board of Checkpoint, and $60,000 in cash fees received for his service as Chairman of the Board and Executive Chairman of Mustang. All Other Compensation for 2025 for Mr. Jin comprises $50,000 in cash fees from Mustang for his service on the Boards of Directors and Company matching 401(k) contributions of $14,000.

&nbsp;&nbsp;&nbsp;&nbsp;(3) Amount represents bonus earned in 2025, subject to final confirmation and approval by the Compensation Committee.

&nbsp;&nbsp;&nbsp;&nbsp;(4) This amount represents a discretionary bonus awarded by the Compensation Committee to Mr. Jin in 2025. Although this bonus was not awarded until 2025, it relates to services performed in 2024 and we have therefore restated Mr. Jin's 2024 compensation to include it.

[**Table of Contents**](#TOC)

&nbsp;&nbsp;&nbsp;&nbsp;(5) $12,500 in cash fees earned from Mustang for Mr. Jin's service on the board of Directors have been added to All Other Compensation for 2024, as the fees should have been included in Mr. Jin's 2024 compensation.

#### Summary of Material Components of Compensation Program
The Company believes in providing to its executive management team a competitive total compensation package featuring a combination of elements. The executive compensation programs are designed to achieve the following objectives:

● reward performance;

● attract, motivate and retain executives of outstanding ability and potential; and

● ensure that executive compensation is rationally related to building stockholder value.

The Board of Directors believes that the Company's executive compensation programs should include short- and long-term components, including cash and equity-based compensation, and should reward consistent performance that meets or exceeds expectations.

#### Base Salaries
Base salaries for the Company's executives are initially established through arm's-length negotiation at the time the executive is hired, taking into account such executive's qualifications, experience, prior salary, the scope of his or her responsibilities, and competitive market compensation paid by other companies for similar positions within the industry. Base salaries are reviewed annually, typically in connection with the annual performance review process, and adjusted from time to time to realign salaries with market levels after taking into account individual responsibilities, performance, and experience. While other of the Company's executives are paid salaries typical within the industry for persons of their experience and expertise, Dr. Rosenwald and Mr. Weiss have elected to largely forego the payment of salary from the Company.

#### Annual Discretionary Bonuses
In addition to the payment of base salaries, the Company believes that discretionary bonuses can play an important role in providing appropriate incentives to its executives to achieve the Company's strategic objectives.

#### Amended and Restated Long Term Incentive Plan
The Fortress Biotech, Inc. Amended and Restated Long Term Incentive Plan (as amended, the "LTIP") is designed to compensate Dr. Rosenwald and Mr. Weiss based on their responsibilities and for their contributions to the successful achievement of certain corporate goals and objectives of the Company. The LTIP awards are intended to enable each executive to share in the successes and risks of the Company. Eligible participants in the LTIP include Dr. Rosenwald, Mr. Weiss, or any limited liability company or limited partnership owned and controlled by Dr. Rosenwald or Mr. Weiss, provided such entity has a bona fide service provider relationship with the Company ("Eligible Entities" and together with Dr. Rosenwald and Mr. Weiss, the "LTIP Participants").

On January 1 of each year, until and including 2035, the LTIP entitles the Company to grant restricted shares of common stock of the Company to each of the LTIP Participants equal to up to one percent (1%) of the total outstanding shares of common stock of the Company, such actual amount to be based upon the achievement of the goals and objectives of each individual as set by the Compensation Committee for the preceding year. In the case of the LTIP Participants, such goals and objectives include, among other things: the Company's in-licensing of new medical technologies of substantial promise; operational and cash management; the Company's issuance of new debt securities; the Company's achievement of developmental, regulatory and clinical milestones in respect of its in-licensed technologies; the recruitment and retention of personnel; share price performance; trading volume of the Company's public securities; and the overall positioning of the Company within its relevant market.

[**Table of Contents**](#TOC)

Each tranche of restricted shares granted under the LTIP after July 15, 2025 vests upon (i) the Company achieving a market capitalization following the grant date that is $100,000,000 greater than the Company's market capitalization on July 16, 2025 and (ii) the participant remaining in service with the Company until (or being involuntarily terminated prior to) July 16, 2035. Each such award would also vest upon a change in control of the Company before July 16, 2035, provided the eligible participant remains in service with the Company until the date of such transaction. If any restricted shares do not vest as described above, they will be subject to a repurchase option by the Company at a nominal price for 90 days following the earlier of July 16, 2035 or the participant's voluntary separation from service with the Company.

In addition, pursuant to the LTIP, upon the formation of each new subsidiary of the Company, the LTIP Participants are to each receive five percent (5%) of the total outstanding shares of common stock of such subsidiary.

In 2025, at expiration of the original 10-year term of the LTIP, Messrs. Rosenwald and Weiss each held 348,838 shares previously granted under 10 separate annual awards under the LTIP. Those shares were scheduled to vest on July 15, 2025, subject to the conditions that each executive remain employed by us as of such date and that the Company's market capitalization, as measured at any time after the grant date of a given annual award, had exceeded by $100 million its market capitalization on July 16, 2015 (provided, however, that the Company must have exercised its repurchase option with respect to any unvested annual award within 90 days after July 15, 2025 or those shares would vest to the LTIP participants). While the service condition was met with respect to each annual award under such original 10-year LTIP term, the market capitalization condition was not met with respect to each such annual award. However, the Board opted not to exercise its repurchase option within the aforementioned 90-day period, allowing all shares to vest to each LTIP participant.

**Retirement Plans** 

We maintain a tax-qualified retirement plan (the "401(k)") plan for eligible employees, including our named executive officers. Eligible employees may make voluntary contributions from their eligible pay and may defer up to 86% of their annual compensation, up to certain limitations imposed by the Internal Revenue Code of 1986, as amended. We match employee contributions in an amount up to 4% of the employee's eligible compensation. All such employee contributions and matching contributions are immediately and fully vested.

#### Equity Incentive Compensation
The Company believes that by providing its executives the opportunity to increase their ownership of Company stock, the interests of its executives will be more closely aligned with the best interests of the Company's stockholders, encouraging long-term performance. The stock awards enable the executive officers to participate in the appreciation of the value of the Company's stock, while personally participating in the risks of business setbacks. The Company grants equity awards to its executives pursuant to the Fortress Biotech, Inc. 2013 Stock Incentive Plan, as has been amended from time to time (the "2013 Plan").

While the Company has awarded stock options to the executive officers as incentives in the past, it more recently has awarded restricted stock or restricted stock units ("RSUs") to its executives. These RSUs or restricted stock awards generally vest in installments over a period of several years. Several of the Company's subsidiaries also periodically grant awards of stock options, restricted stock or RSUs to executive officers of the Company in respect of their service as officers or directors of those subsidiaries.

[**Table of Contents**](#TOC)

#### OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-END
The following table sets forth certain information regarding outstanding equity awards held by the Company's named executive officers, in securities of the Company and its subsidiaries, as of December 31, 2025.

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Option Awards** | **Option Awards** | **Option Awards** | **Option Awards** | **Stock Awards** | **Stock Awards** | **Stock Awards** | **Stock Awards** |
| <br>**Name** | <br>**Number of**<br>**Securities**<br>**Underlying**<br>**Unexercised**<br>**Options/**<br>**Warrant**<br>**Exercisable (#)** | <br>**Number of**<br>**Securities**<br>**Underlying**<br>**Unexercised**<br>**Options**<br>**Unexercisable (#)** | <br><br><br>**Option/**<br>**Warrant**<br>**Exercise**<br>**Price ($)** | <br>**Option/**<br>**Warrant**<br>**Expiration**<br>**Date** | <br><br>**Number of**<br>**Shares or**<br>**Units of**<br>**Stock That**<br>**Have Not**<br>**Vested (#)** | <br>**Market**<br>**Value of**<br>**Shares or**<br>**Units of**<br>**Stock That**<br>**Have Not**<br>**Vested ($)**<sup>(1)</sup> | <br>**Equity**<br>**Incentive**<br>**Plan**<br>**Awards:**<br>**Number or**<br>**Unearned**<br>**Shares (#)** | **Equity**<br>**Incentive**<br>**Plan Awards:**<br>**Market or**<br>**Payout**<br>**Value of**<br>**Unearned**<br>**Shares ($)**<sup>(1)</sup> |
| Lindsay A. Rosenwald, M.D. | 888<br><sup>(2)</sup>  | 445 | $85.50 | 6/30/2033 |  | $— | 475163<br><sup>(3)</sup>  | $1739097 |
|  | 10000<br><sup>(4)</sup>  | 20000 | 2.46 | 9/23/2034 | 57173<br><sup>(5)</sup>  | 440804 |  |  |
|  |  |  |  |  | 144<br><sup>(6)</sup>  | 141 |  |  |
| David Jin | 2500<br><sup>(7)</sup>  | 833 | 85.50 | 6/30/2033 | 5000<br><sup>(8)</sup>  | 38550 |  |  |
|  | 125000<br><sup>(9)</sup>  | 125000 | 1.29 | 10/10/2033 | 16250<br><sup>(10)</sup>  | 11053 |  |  |
|  |  |  |  |  | 750000<br><sup>(11)</sup>  | 2745000 |  |  |
|  |  |  |  |  | 70000<br><sup>(12)</sup>  | 256200 |  |  |
|  |  |  |  |  | 18750<br><sup>(13)</sup>  | 68625 |  |  |
| Michael S. Weiss |  |  |  |  | 144<br><sup>(6)</sup>  | 141 | 475163<br><sup>(3)</sup>  | 1739097 |
|  |  |  |  |  | 87970<br><sup>(14)</sup>  | 321970 |  |  |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Based on the closing stock price on the Nasdaq Capital Market on the last trading day of the most recently completed fiscal year, as applicable, Fortress: $3.66, Journey: $7.71, Mustang: $0.98 and Avenue: $0.68.

&nbsp;&nbsp;&nbsp;&nbsp;(2) Represents options in respect of Avenue common stock, which vest (or vested) in equal installments on January 1 of each of 2024, 2025 and 2026.

(3)Represents restricted shares of the Company that vest if both of the following conditions are met: (a) there is an increase in the market capitalization of the Company of at least $100 million since January 1, 2026 and before July 16, 2035, and (b) the grantee (or a limited liability company or limited partnership owned by the grantee) either remains in service with the Company through July 16, 2035 or experiences an involuntary separation prior to such date.

&nbsp;&nbsp;&nbsp;&nbsp;(4) Represents options in respect of Avenue common stock, which vest (or vested) in equal installments on January 1 of each of 2025, 2026 and 2027.

[**Table of Contents**](#TOC)

&nbsp;&nbsp;&nbsp;&nbsp;(5) Represents restricted shares in Journey that vest as follows: 7,173 restricted shares vest on June 25, 2026; 16,666 restricted shares vest on August 5, 2026; 16,667 restricted shares vest on August 5, 2027; and 16,667 restricted shares vest on August 5, 2028.

&nbsp;&nbsp;&nbsp;&nbsp;(6) Represents restricted shares in Mustang that vest on July 5, 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(7) Represents options in respect of Avenue common stock, which vest (or vested) in equal installments on August 1 of each of 2023, 2024, 2025 and 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(8) Represents restricted shares in Journey that vest on July 21, 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(9) Represents options in respect of Urica common stock, which vest (or vested) in equal installments on October 10 of each of 2023, 2024, 2025 and 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(10) Represents restricted stock units in Avenue that vest in equal installments on September 23 of each of 2025 and 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(11) Represents deferred restricted stock units of the Company that vest in 16 equal quarterly installments through the period ending December 31, 2028.

&nbsp;&nbsp;&nbsp;&nbsp;(12) Represents deferred restricted stock units of the Company that vest in 12 equal quarterly installments through the period ending December 31, 2027.

&nbsp;&nbsp;&nbsp;&nbsp;(13) Represents deferred restricted stock units of the Company that vest in 22 equal monthly installments through the period ending October 31, 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(14) Represents restricted shares of the Company that vest on December 19, 2027.

#### Summary of Employment or Agreements and Arrangements

#### Executive Employment Agreements
The Company has not entered into employment agreements with any of Dr. Rosenwald, Mr. Weiss, or Mr. Jin.

**Clawback Policy**

Pursuant to Nasdaq listing requirements, we have adopted a policy providing for the recovery of erroneously awarded incentive-based compensation received by our executive officers or the executive officers of one of our subsidiaries during an applicable recovery period (the "Clawback Policy"). Under the Clawback Policy, in the event that financial results upon which a cash or equity-based incentive award was based becomes the subject of a financial restatement that is required because of material non-compliance with financial reporting requirements, the Compensation Committee will conduct a review of awards covered by the Clawback Policy and recoup any erroneously awarded incentive-based compensation to ensure that the ultimate award reflects the financial results as restated. The Clawback Policy covers any cash or equity-based incentive compensation award that was paid, earned or granted to covered executive officers during the last completed three fiscal years immediately preceding the date on which we are required to prepare the accounting restatement.

**Timing of Equity Awards**

While we have no set policy or practice regarding the timing of stock option awards or similar instruments in relation to the disclosure of material nonpublic information, we do not time the release of material information to affect the value of stock options. In general, the timing of stock option awards is dictated by the event or circumstance giving rise to the award and the schedules of the directors responsible for approving the award. In 2025, options were not issued to our named executive officers during the period beginning four business days before and ending one business day after the filing of a Form 10-Q, Form 10-K or Form 8-K that discloses material nonpublic information. If, in the future, a stock option grant is made at a time that material nonpublic information exists, the directors approving the award would be responsible for considering the anticipated effect of that information on our stock price and would take such effect into account when sizing and pricing the award.

[**Table of Contents**](#TOC)

#### EQUITY COMPENSATION PLAN INFORMATION
Our equity compensation plans consist of the Coronado Biosciences, Inc. 2012 Employee Stock Purchase Plan, the Fortress Biotech, Inc. 2013 Stock Incentive Plan, as amended, and the Fortress Biotech, Inc. Long Term Incentive Plan, all of which were approved by our stockholders. We do not have any equity compensation plans or arrangements that have not been approved by our stockholders.

The following table sets forth the indicated information as of December 31, 2025 with respect to our equity compensation plans of the Company:

---

| | | | |
|:---|:---|:---|:---|
| <br>**Plan Category** | <br>**Number of**<br>**Securities to be**<br>**Issued Upon**<br>**Exercise of**<br>**Outstanding**<br>**Options,**<br>**Restricted**<br>**Stock Units,**<br>**Warrants and**<br>**Rights (a)** <sup>(1)</sup> | <br>**Weighted-**<br>**Average Exercise**<br>**Price of**<br>**Outstanding**<br>**Options,**<br>**Warrants and**<br>**Rights** <sup>(2)</sup> | **Number of** <br>**Securities**<br>**Remaining**<br>**Available for**<br>**Future Issuance**<br>**Under Equity**<br>**Compensation**<br>**Plans (Excluding**<br>**Securities**<br>**Reflected in**<br>**Column(a))** <sup>(3)</sup> |
| Equity compensation plan approved by shareholders | 3346833 | $— | 8360321 |
| Equity compensation plan not approved by shareholders |  |  |  |
| Total | 3346833 | $— | 8360321 |

---

(1) Includes 361,846 deferred shares of restricted stock, 1,612,321 restricted stock units, and 1,372,666 deferred restricted stock units.

(2) Restricted stock units are not included in calculation of weighted-average exercise price, as they do not have an exercise price.

(3) Includes 7,429,595 shares available in the Fortress Biotech, Inc. 2013 Stock Incentive Plan and 930,726 shares under the Coronado Biosciences, Inc. 2012 Employee Stock Purchase Plan.

[**Table of Contents**](#TOC)

#### PAY VERSUS PERFORMANCE
The following table shows the past three fiscal years' total compensation for our named executive officers as set forth in the Summary Compensation Table, the "compensation actually paid" to our named executive officers (as determined under SEC rules), our total shareholder return ("TSR"), and our net income.

SEC rules require certain adjustments be made to the Summary Compensation Table totals to determine Compensation Actually Paid as reported in the Pay Versus Performance Table. Compensation Actually Paid does not necessarily represent cash and/or equity value transferred to the applicable named executive officer without restriction, but rather is a valuation calculated under applicable SEC rules. In general, Compensation Actually Paid is calculated as summary compensation table total compensation adjusted to (a) include the value of any pension benefit (or loss) attributed to the past fiscal year, including on account of any amendments adopted during such year; and (b) include the fair market value of equity awards as of December 31, 2025 or, if earlier, the vesting date (rather than the grant date) and factor in dividends and interest accrued with respect to such awards, if applicable. For purposes of the disclosure below, no pension valuation adjustments were required.

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Year** | **Summary Compensation Table Total for Principal Executive Officer ("PEO")**<sup>(1)</sup> | **Compensation Actually Paid to PEO**<sup>(2)</sup> | **Average Summary Compensation Table Total for Non-PEO Named Executive Officers ("NEOs")**<sup>(3)</sup> | **Average Compensation Actually Paid to Non-PEO NEOs**<sup>(3)</sup> | **Value of Initial Fixed $100 Investment Based on Total Shareholder Return ("TSR")**<sup>(4)</sup> | **Net Income (Loss) (millions)**<sup>(5)</sup> |
| 2025 | $2887256 | $3555640 | $1552918 | $3285920 | $37 | $(33) |
| 2024 | 1380197 | 807503 | 1897806<br><sup>(6)</sup> | 1432093<br><sup>(6)</sup> | 21 | (121) |
| 2023 | 1122585 | (1904079) | 1221446 | (1829434) | 31 | (154) |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Dr. Rosenwald was the Registrant's PEO for each of the 2025, 2024 and 2023 fiscal years.

&nbsp;&nbsp;&nbsp;&nbsp;(2) The amounts disclosed reflect the adjustments listed in the tables below to the amounts reported in the Summary Compensation Table for PEO:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Year** | **Less: Grant Date Value of Equity Awards** | **Year-End Fair Value of Unvested Awards Granted During 2025** | **Vesting Date Value of Awards that were Granted and Vested in 2025** | **Year-Over-Year Change in Fair Value of Unvested Awards Granted in Prior Years** | **Change in Value of Awards Vesting During 2025 that were Granted in Prior Years** | **Total Adjustments** |
| 2025 | $(2199592) | $2179900 | $50000 | $(52449) | $690523 | $668382 |

---

&nbsp;&nbsp;&nbsp;&nbsp;(3) For the 2025, 2024 and 2023 fiscal years, our Non-PEO NEOs were: David Jin and Michael S. Weiss. The amounts disclosed reflect the adjustments listed in the table below to the amounts reported in the Summary Compensation Table for Non-PEO NEOs:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Year** | **Less: Grant Date Value of Equity Awards** | **Year-End Fair Value of Unvested Awards Granted During 2025** | **Vesting Date Value of Awards that were Granted and Vested in 2025** | **Year-Over-Year Change in Fair Value of Unvested Awards Granted in Prior Years** | **Change in Value of Awards Vesting During 2025 that were Granted in Prior Years** | **Total Adjustments** |
| 2025 | $(894548) | $873540 | $28992 | $931923 | $793094 | $1733002 |

---

&nbsp;&nbsp;&nbsp;&nbsp;(4) Represents the cumulative TSR for a $100 investment in Fortress' common stock, assuming such investment occurred on December 31, 2022 and all dividends were reinvested.

&nbsp;&nbsp;&nbsp;&nbsp;(5) The dollar amounts reported represent the amount of net income (loss) reflected in our consolidated audited financial statements for the applicable year.

&nbsp;&nbsp;&nbsp;&nbsp;(6) Includes adjustment to the bonus amount awarded to, and cash fees earned by, Mr. Jin for 2024 as reflected in the Summary Compensation Table for 2024, as described in footnotes 4 and 5 to the Summary Compensation Table. No additional reconciliation for fiscal year 2024 is provided because the corrections are tied to cash-based compensation.

[**Table of Contents**](#TOC)

**Analysis of the Information Presented in the Pay Versus Performance Table**

*Compensation Actually Paid and Net Income (Loss)*

Due to the nature of our Company's consolidated financials and primary focus on research and development of novel therapies, our company has not historically utilized net income (loss) as a performance measure for our executive compensation program.

![Graphic](fbio-20260617xdef14a_a008.jpg)

*PEO and Non-PEO NEO Compensation Actually Paid and Company Total Shareholder Return ("TSR")*

The following chart sets forth the relationship between Compensation Actually Paid to our PEO, the average of Compensation Actually Paid to our Non-PEO NEOs, and the Company's TSR over the period covering fiscal years 2023, 2024 and 2025. A large component of our executive compensation is equity-based to align compensation with performance, but also includes other appropriate incentives such as cash bonuses that are designed to incentivize our executives to achieve annual corporate goals. We believe the equity-based compensation strongly aligns our PEO and Non-PEO NEOs' interests with those of our shareholders to maximize long-term value and encourages long-term employment.

[**Table of Contents**](#TOC)

![Graphic](fbio-20260617xdef14a_a009.jpg)

*All information provided above under the "Pay Versus Performance" heading will not be deemed to be incorporated by reference in any filing of our company under the Securities Act of 1933, as amended, whether made before or after the date hereof and irrespective of any general incorporation language in any such filing.*

#### DIRECTOR COMPENSATION
Non-employee directors are compensated pursuant to the Company's Non-Employee Director Compensation Policy and each non-employee director is eligible to receive a board fee of $30,000 annually, payable in quarterly installments. Audit Committee members are eligible to receive an additional committee fee of $7,500 annually, payable in quarterly installments, and the chair of the Audit Committee is eligible to receive an additional Audit Committee chair fee of $55,000 annually, payable in quarterly installments. Compensation Committee, Nominating and Governance Committee, and Strategic Transaction Committee members are each eligible to receive an additional committee fee of $5,000 annually, payable in quarterly installments, and chairs of each of those committees are eligible to receive a committee chair fee of $10,000 annually, payable in quarterly installments.

Non-employee directors may also receive stock options, restricted stock, or a restricted stock unit grant for shares of the Company's common stock upon appointment and on an annual basis thereafter. Similarly, Strategic Transaction Committee members may also receive an additional equity award upon appointment to that committee and on an annual basis thereafter.

On January 1, 2025, all non-employee directors received $100,000 worth of restricted stock, with the number of shares determined in each case based on the closing price of our common stock on the last trading day prior to the grant date, and in each case vesting in three equal installments on January 1 of 2026, 2027 and 2028. There are no additional changes to director compensation planned for 2026.

[**Table of Contents**](#TOC)

#### Non-Qualified Deferred Compensation
On March 12, 2015, the Compensation Committee of the Board approved the Deferred Compensation Plan for Directors (the "Plan"). The Plan is administered by the Compensation Committee.

Pursuant to the Plan, any non-employee director (a "Participant") can defer all or a portion of such Participant's unearned annual fees, meeting fees and committee fees, including restricted stock and restricted stock units. Deferred cash compensation will be converted into a number of stock units, determined based upon the closing price of the Company's common stock on the date such fees would otherwise have been payable and placed into the Participant's deferred compensation account ("Account"). Deferred restricted stock unit grants will be converted on a share-for-share basis on the date such restricted stock units would otherwise have been payable and placed into the Participant's Account.

On the tenth business day of January of the year following the Participant's separation from service on the Board due to resignation, removal, failure to be re-elected or retirement, the amount of deferred compensation in the Participant's Account will be distributed to the Participant in a lump sum payment of a number of shares of the Company's common stock under the Plan equal to the number of whole stock units in the Account and cash in lieu of any fractional shares. Distributions from the Account may be accelerated in the event of the Participant's death or upon a corporate transaction (as defined in the Plan).

**Fiscal 2025 Non-Employee Director Compensation**

The following table and related footnotes show the compensation paid to or accrued for the benefit of the Company's non-employee directors in the fiscal year ended December 31, 2025.

---

| | | | |
|:---|:---|:---|:---|
| <br>**Name** | **Fees Earned**<br>**or Paid in**<br>**Cash**<sup>(1)</sup>**($)** | **Stock**<br>**Awards**<sup>(2)</sup><br>**($)** | <br>**Total**<br>**($)** |
| Jimmie Harvey, Jr., M.D. | $47500 | $100001<br><sup>(3)</sup>  | $147501 |
| Malcolm Hoenlein | 35000 | 100001<br><sup>(4)</sup>  | 135001 |
| Dov Klein, CPA | 100000 | 100001<br><sup>(5)</sup>  | 200001 |
| J. Jay Lobell | 67500 | 100001<br><sup>(3)</sup>  | 167501 |
| Kevin L. Lorenz, J.D. | 30000 | 100001 | 130001 |
| Lucy Lu, M.D.<sup>(6)</sup> | 15000 | 100001<br><sup>(3)</sup>  | 115001 |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Represents director and committee fees earned in 2025.

&nbsp;&nbsp;&nbsp;&nbsp;(2) Amounts listed represent the aggregate fair value amount computed as of the grant date of each award during 2025 in accordance with FASB ASC Topic 718, as described in Note 13 of the financial statements contained in the Company's Annual Report on Form 10-K for the year ended December 31, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;(3) In 2025, Drs. Harvey, Lobell and Lu elected to defer 100% of the value of their stock awards. This amount was credited to each of their deferred compensation accounts, respectively.

&nbsp;&nbsp;&nbsp;&nbsp;(4) In 2025, Mr. Hoenlein elected to defer 25% of the value of his stock award. This amount was credited to his deferred compensation account.

&nbsp;&nbsp;&nbsp;&nbsp;(5) In 2025, Mr. Klein elected to defer 50% of the value of his stock award. This amount was credited to his deferred compensation account.

&nbsp;&nbsp;&nbsp;&nbsp;(6) Dr. Lu resigned from the Board effective April 15, 2025 and accepted an offer to become the Company's Chief Strategy Officer (see "*Related-Person Transactions – Other Related Parties*" for details regarding her compensation earned as an employee).

At December 31, 2025, the aggregate number of restricted stock issued to each non-employee director that remains unvested was as follows: Dr. Harvey, 51,605 restricted stock awards ("RSAs"); Mr. Hoenlein, 50,494 RSAs; Mr. Klein, 51,605 RSAs; Mr. Lobell, 49,383 RSAs; and Mr. Lorenz, 50,494 RSAs.

[**Table of Contents**](#TOC)

#### DELINQUENT SECTION 16(A) BENEFICIAL OWNERSHIP REPORTS
Section 16(a) of the Exchange Act requires our directors, executive officers and persons who own more than 10% of the shares of our common stock to file an initial report of ownership on Form 3 and changes in ownership on Form 4 or Form 5 with the SEC. Such officers, directors and 10% stockholders are also required by SEC rules to furnish us with copies of any Forms 3, 4 or 5 that they file. The SEC rules require us to disclose late filings of initial reports of stock ownership and changes in stock ownership by our directors, executive officers and 10% stockholders. Based solely on a review of copies of the Forms 3, 4 and 5 furnished to us by reporting persons and any written representations furnished by certain reporting persons, we believe that, during the fiscal year ended December 31, 2025, no Section 16(a) filings were untimely.

#### RELATED-PERSON TRANSACTIONS
Since January 1, 2025, the Company has not been a party to any transaction in which the amount involved exceeded or will exceed $120,000, and in which any of its directors, named executive officers or beneficial owners of more than 5% of the Company's capital stock, or an affiliate or immediate family member thereof, had or will have a direct or indirect material interest, other than as set forth below and other than compensation, termination, and change-in-control arrangements, all of which are described under "Executive Compensation" above.

The written charter of the Audit Committee authorizes, and the Nasdaq Stock Market listing rules require, the Audit Committee to review and approve related-party transactions. In reviewing related-party transactions, the Audit Committee applies the basic standard that transactions with affiliates should be made on terms no less favorable to the Company than could have been obtained from unaffiliated parties. Therefore, the Audit Committee reviews the benefits of the transactions, terms of the transactions and the terms available from unrelated third parties, as applicable. All transactions other than compensatory arrangements between the Company and its officers, directors, principal stockholders and their affiliates will be approved by the Audit Committee or a majority of the disinterested directors, and will continue to be on terms no less favorable to the Company than could be obtained from unaffiliated third parties.

#### Other Related Parties
The Company's Chairman, President and Chief Executive Officer, individually and through certain trusts over which he has voting and dispositive control, beneficially owned approximately 19.1% and 21.5% of the Company's issued and outstanding Common Stock as of December 31, 2025 and 2024, respectively. The Company's Executive Vice Chairman, Strategic Development individually owned approximately 6.2% and 5.4% of the Company's issued and outstanding Common Stock as of December 31, 2025 and 2024, respectively.

Dr. Lucy Lu, previously a member of the Company's Board of Directors, became the Company's Chief Strategy Officer effective April 15, 2025. Pursuant to her offer letter, she is eligible to earn an annual base salary of $420,000 and a target annual bonus opportunity of 40% of her base salary or $168,000. Her actual base salary earned in 2025 was $292,923 and Dr. Lu also received a signing bonus of $30,000. In 2025, Dr. Lu also received a grant of 300,000 RSUs vesting over four (4) years in quarterly increments over sixteen (16) equal tranches, with the final tranche vesting on April 15, 2029.

[**Table of Contents**](#TOC)

#### Shared Services Agreement with TGTX
In July 2015, TGTX and the Company entered into an arrangement to share the cost of certain research and development employees of the Company. The Company's Executive Vice Chairman, Strategic Development, is the Executive Chairman and Chief Executive Officer of TGTX. Under the terms of the agreement, TGTX reimbursed the Company for the salary and benefit costs associated with these employees based upon actual hours worked on TGTX-related projects. In connection with the shared services agreement, the Company invoiced TGTX $0.8 million and $0.9 million, respectively. At December 31, 2025, there was approximately $39,000 due from TGTX related to this arrangement.

#### Desk Share Agreement with TGTX
The desk share agreement between the Company and TGTX (the "Desk Share Agreement"), as amended, required TGTX to pay 65% of the average annual rent of the Company's New York, NY office space. In connection with the Company's Desk Share Agreement for the New York, NY office space, for the years ended December 31, 2025 and 2024, the Company paid $2.7 million and $2.9 million in rent, respectively, and invoiced TGTX approximately $1.8 million and $1.7 million respectively, for its prorated share of the rent base for the New York, NY office space. At December 31, 2025, there were no amounts due from TGTX related to this arrangement.

The Company has since entered into a sublease agreement for all of its leased space in the New York, NY office, and amended the Desk Share Agreement with TGTX such that costs associated with the New York, NY lease during the term of the sublease that are not reimbursed or otherwise paid by the subtenant under the sublease agreement will be split equally between the Company and TGTX.

**Shared Services Agreement with Journey** 

In November 2021, Journey and the Company entered into an arrangement to share the cost of certain legal, finance, regulatory, and research and development employees. The Company's Executive Chairman and Chief Executive Officer is the Executive Chairman of Journey. Under the terms of the arrangement, Journey reimburses the Company for the salary and benefit costs associated with these employees based upon actual hours worked on Journey-related projects. In addition, Journey reimburses the Company for various payroll-related costs and selling, general and administrative costs incurred by Fortress for the benefit of Journey. For the years ended December 31, 2025 and 2024, the Company's employees have provided services to Journey totaling approximately $43,000 and $38,000, respectively. At December 31, 2025, approximately $0.5 million was due from Journey, primarily related to reimbursable expenses incurred by Fortress on behalf of Journey.

#### Founders Agreement and Management Services Agreement
The Company has entered into founders agreements (the "Founders Agreements") with each of the Fortress partner companies and subsidiaries listed in the table below. Pursuant to each Founders Agreement, in exchange for the time and capital expended in the formation of each partner company/subsidiary and the identification of specific assets the acquisition of which result in the formation of a viable emerging growth life science company, Fortress will loan each such partner company/subsidiary an amount representing the up-front fee required to acquire assets, as well as certain development costs. Each Founders Agreement has a term of 15 years, which upon expiration automatically renews for successive one-year periods unless terminated by the Company or upon a Change in Control (as defined in the Founders Agreement) occurs. In connection with each Founders Agreement the Company received a number of either Class A Preferred shares or Class A Common Stock.

The Class A Preferred Stock or Class A Common Stock (such stock, the "Founders Stock") is identical to common stock other than as to voting rights, conversion rights and the Payment-in-Kind ("PIK") Dividend right (as described below). Each share of Founders Stock is entitled to vote the number of votes that is equal to one and one-tenth (1.1) times a fraction, the numerator of which is the sum of (A) the shares of outstanding common stock and (B) the whole shares of common stock into which the shares of outstanding Founders Stock are convertible and the denominator of which is the number of shares of outstanding Founders Stock. Thus, the Founders Stock will at all times constitute a voting majority. Each share

[**Table of Contents**](#TOC)

of Founders Stock is convertible, at the holder's option, into one fully paid and nonassessable share of common stock of such partner company/subsidiary, subject to certain adjustments.

The holders of Founders Stock, as a class, are entitled receive on each effective date or "Trigger Date" (defined as the date that the Company first acquired, whether by license or otherwise, ownership rights to a product) of each agreement (each a "PIK Dividend Payment Date") and on each anniversary date of such date until the date all outstanding Founders Stock is converted into common stock or redeemed (and the purchase price is paid in full), pro rata per share dividends paid in additional fully paid and nonassessable shares of common stock ("PIK Dividends") such that the aggregate number of shares of common stock issued pursuant to such PIK Dividend is equal to two and one-half percent (2.5%) of such partner company or subsidiary's fully-diluted outstanding capitalization on the date that is one (1) business day prior to any PIK Dividend Payment Date. The Company has reached agreements with several of the partner companies and subsidiaries to change the PIK Dividend Interest Payment Date to January 1 of each year - a change that has not and will not result in the issuance of any additional partner company/subsidiary common stock beyond that amount to which the Company would otherwise be entitled absent such change(s). The Company owns 100% of the Founders Stock of each partner company/subsidiary that has a Founders Agreement with the Company.

As additional consideration under the Founders Agreement, each partner company and subsidiary with which the Company has entered into a Founders Agreement will also: (i) pay an equity fee in shares of the common stock of such partner company/subsidiary, payable within five (5) business days of the closing of any equity or debt financing for each partner company/subsidiary or any of its respective subsidiaries that occurs after the effective date of the Founders Agreement and ending on the date when the Company no longer has majority voting control in such partner company or subsidiary's voting equity, equal to two and one-half (2.5%) of the gross amount of any such equity or debt financing; and (ii) pay a cash fee equal to four and one-half percent (4.5%) of such partner company or subsidiary's annual net sales, payable on an annual basis, within ninety (90) days of the end of each calendar year. In the event of a Change in Control, each such partner company/subsidiary will pay a one-time change in control fee equal to five (5x) times the product of (A) net sales for the twelve (12) months immediately preceding the change in control and (B) four and one-half percent (4.5%). In the case of Urica, however, the obligation to pay Fortress royalties under the Founders Agreement survives any such Change in Control.

The following table summarizes, by subsidiary, the effective date of the Founders Agreements and PIK dividend or equity fee payable to the Company in accordance with the terms of the Founders Agreements, exchange agreements (the "Exchange Agreements") and the partner companies'/subsidiaries' certificates of incorporation.

---

| | | | |
|:---|:---|:---|:---|
| <br>**Partner Company/Subsidiary** | <br>**Effective Date**<sup>1</sup> | **PIK Dividend**<br>**as a % of fully**<br>**diluted**<br>**outstanding**<br>**capitalization** | <br>**Class of Stock**<br>**Issued** |
| Avenue | February 17, 2015 | 2.5% | Common Stock |
| Cellvation | October 31, 2016 | 2.5% | Common Stock |
| Checkpoint | March 17, 2015 | —%<sup>2</sup>  | Common Stock |
| Cyprium | March 13, 2017 | 2.5% | Common Stock |
| Helocyte | March 20, 2015 | 2.5% | Common Stock |
| Mustang | March 13, 2015 | 2.5% | Common Stock |
| Oncogenuity | April 22, 2020 <sup>3</sup> | 2.5% | Common Stock |
| Urica | November 7, 2017 <sup>3</sup> | 2.5% | Common Stock |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Represents the effective date of each subsidiary's Founders Agreement. Each PIK dividend and equity fee is payable on the annual anniversary of the effective date of the original Founders Agreement or has since been amended to January 1 of each calendar year.

[**Table of Contents**](#TOC)

&nbsp;&nbsp;&nbsp;&nbsp;(2) Instead of a PIK dividend, Checkpoint paid the Company an annual equity fee in shares of Checkpoint's common stock equal to 2.5% of Checkpoint's fully diluted outstanding capitalization. Under the support agreement signed by the Company in connection with Checkpoint's merger with Sun Pharmaceutical Industries Limited ("Sun Pharma"), completed in May 2025, the Company also agreed to forgo any further payment, dividend or distribution, or issuance or transfer of securities by Checkpoint on or after the date of the support agreement under the Founders Agreement. Checkpoint was acquired by Sun Pharma in May 2025 and the Founders Agreement terminated at that time.

(3)Represents the Trigger Date, the date that the Fortress partner company first acquires, whether by license or otherwise, ownership rights in a product.

#### Equity Fees and PIK Dividends
The following table summarizes, by subsidiary, the value of the PIK dividend or equity fee recorded by the Company in accordance with the terms of the Founders Agreements, Exchange Agreements and the partner companies'/subsidiaries' certificates of incorporation for the years ended December 31, 2025 and 2024 ($ in thousands):

---

| | | | |
|:---|:---|:---|:---|
| | | **Year Ended December 31,**  | **Year Ended December 31,**  |
| <br>**Partner Company** | **PIK Dividend**<br>**Date** | **2025** | **2024** |
| Avenue | January 1 | 130 | 410 |
| Cellvation | October 31 | 7 | 10 |
| Checkpoint<sup>1</sup> | January 1 | 53 | 8633 |
| Cyprium | January 1 | 299 | 291 |
| Helocyte | January 1 | 40 | 39 |
| Mustang | January 1 | 667 | 940 |
| Oncogenuity | May 8 | 9 | 9 |
| Urica | November 25 | 87 | 514 |
| Fortress |  | (1292) | (10846) |
| Total |  | $— | $— |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Instead of a PIK dividend, Checkpoint paid the Company an annual equity fee in shares of Checkpoint's common stock equal to 2.5 % of Checkpoint's fully diluted outstanding capitalization. Due to the deconsolidation of Checkpoint in May 2025 related to its acquisition by Sun Pharma transaction, Checkpoint no longer has this obligation to the Company.

[**Table of Contents**](#TOC)

#### Management Services Agreements
The Company has entered into Management Services Agreements (the "MSAs") with certain of its partner companies and subsidiaries. Pursuant to each MSA, the Company's management and personnel provide advisory, consulting and strategic services to each partner company/subsidiary that has entered into an MSA with Fortress for a period of five years (with such term automatically extending for additional five-year periods unless terminated by Fortress or the applicable partner company/subsidiary at least 90 days prior to any such initial or additional term). Such services may include, without limitation, (i) advice and assistance concerning any and all aspects of each such company's operations, clinical trials, financial planning and strategic transactions and financings and (ii) conducting relations on behalf of each such company with accountants, attorneys, financial advisors and other professionals. Each such partner company/subsidiary is obligated to utilize clinical research services, medical education, communication and marketing services and investor relations/public relation services of companies or individuals designated by Fortress, provided those services are offered at market prices. However, such companies are not obligated to take or act upon any advice rendered from Fortress, and Fortress shall not be liable to any such partner company/subsidiary for its actions or inactions based upon Fortress' advice. Fortress and its affiliates, including all members of Fortress' Board of Directors, have been contractually exempted from fiduciary duties to each such partner company/subsidiary relating to corporate opportunities.

The following table summarizes, by partner company/subsidiary, the effective date of the MSA and the annual consulting fee payable by the partner company/subsidiary to Fortress in quarterly installments ($ in thousands):

---

| | | | |
|:---|:---|:---|:---|
| | | **Year Ended December 31,** | **Year Ended December 31,** |
| <br>**Partner Company/Subsidiary** | <br>**Effective Date** | **2025** | **2024** |
| Avenue<sup>1</sup> | February 17, 2015 | $500 | $250 |
| Cellvation | October 31, 2016 | 500 | 500 |
| Checkpoint<sup>2</sup> | March 17, 2015 | 208 | 500 |
| Cyprium | March 13, 2017 | 500 | 500 |
| Helocyte | March 20, 2015 | 500 | 500 |
| Mustang | March 13, 2015 | 500 | 500 |
| Oncogenuity | February 10, 2017 | 500 | 500 |
| Urica | November 7, 2017 | 500 | 500 |
| Fortress |  | (3708) | (3750) |
| Total |  | $— | $— |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) Avenue's MSA fee for 2024 was subject to a Subscription and Forgiveness Agreement signed in November 2024.

&nbsp;&nbsp;&nbsp;&nbsp;(2) Due to the deconsolidation of Checkpoint in May 2025 related to its acquisition by Sun Pharma, Checkpoint no longer has this obligation to the Company.

**Fees and Stock Grants Received by Fortress**

Fees recorded in connection with the Fortress' agreements with its subsidiaries and partner companies are eliminated in consolidation. These include management services fees, issuance of common shares of partner companies in connection with third party raises and annual stock dividend or issuances on the anniversary date of respective Founders Agreements.

[**Table of Contents**](#TOC)

#### STOCK OWNERSHIP OF OUR DIRECTORS, EXECUTIVE OFFICERS, AND 5% BENEFICIAL OWNERS
The following table shows information, as of April 16, 2026, concerning the beneficial ownership of our common stock by:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;● each person we know to be the beneficial owner of more than 5% of our common stock;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;● each of our current directors;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;● each of our Named Executive Officers ("NEOs"); and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;● all current directors and NEOs as a group.

As of April 16, 2026, there were 33,200,322 shares of our common stock outstanding. In order to calculate a specific stockholder's percentage of beneficial ownership, we include in that stockholder's calculation those shares underlying options, warrants, or restricted stock units beneficially owned by that stockholder that are vested or that will vest within 60 days of the April 16, 2026. Shares of restricted stock are deemed to be outstanding. Options, warrants, or restricted stock units held by other stockholders that are not attributed to the named beneficial owner are disregarded in this calculation. Beneficial ownership is determined in accordance with the rules of the SEC and includes voting or investment power with respect to the shares of our common stock. Unless we have indicated otherwise, each person named in the table below has sole voting power and investment power for the shares listed opposite such person's name, except to the extent authority is shared by spouses under community property laws.

---

| | | | | |
|:---|:---|:---|:---|:---|
| <br>**Name of Beneficial Owner** | <br>**Shares**<br>**Owned** | **Shares Under**<br>**Exercisable**<br>**Options, Warrants**<br>**and Unvested**<br>**Restricted**<br>**Stock**<br>**Units**<sup>(1)</sup> | <br>**Total Shares**<br>**Beneficially**<br>**Owned** | <br>**Percentage**<br>**Beneficially**<br>**Owned** |
| Lindsay A. Rosenwald, M.D.<sup>(2)</sup> | 4586841 | 2331174 | 6918015 | 19.5% |
| Michael S. Weiss<sup>(3)</sup> | 2276562 | 147058 | 2423620 | 7.3% |
| J. Jay Lobell | 192397 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;- | 192397 | \*% |
| Jimmie Harvey, Jr., M.D. | 146704 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;- | 146704 | \*% |
| Dov Klein, CPA<sup>(4)</sup> | 130105 | 2666 | 132771 | \*% |
| David Jin <sup>(5)</sup> | 21571 | 164375 | 185946 | \*% |
| Malcolm Hoenlein | 115747 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;- | 115747 | \*% |
| Kevin L. Lorenz, J.D. | 101009 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;- | 101009 | \*% |
| All current executive officers (including NEOs) and directors as a group (9 persons) | 7570936 | 2645273 | 10216209 | 28.5% |

---

\* Less than 1%

&nbsp;&nbsp;&nbsp;&nbsp;(1) Includes options exercisable currently, options vesting within 60 days of April 16, 2026 and restricted stock units vesting within 60 days of April 16, 2026.

&nbsp;&nbsp;&nbsp;&nbsp;(2) Includes 4,525,919 shares held directly by Dr. Rosenwald, 11,398 shares held by Capretti Grandi LLC, and 49,524 shares held by PAB Merger LLC and 2,331,174 shares underlying warrants that are currently exercisable. Dr. Rosenwald has voting and dispositive control over the shares held by Capretti Grandi LLC and PAB Merger LLC. Does not include 96,919 shares of common stock held by trusts established for the benefit of Dr. Rosenwald's family, over which Dr. Rosenwald does not have any voting or dispositive control.

&nbsp;&nbsp;&nbsp;&nbsp;(3) Includes 147,058 shares underlying warrants that are currently exercisable.

&nbsp;&nbsp;&nbsp;&nbsp;(4) Includes 2,666 vested restricted stock units that have been deferred.

&nbsp;&nbsp;&nbsp;&nbsp;(5) Includes 164,375 deferred restricted stock units.

[**Table of Contents**](#TOC)

#### PROPOSAL ONE: ELECTION OF DIRECTORS; NOMINEES
Our Fourth Amended and Restated Bylaws provide that the Board shall consist of no less than one (1) and no more than nine (9) members, as determined from time to time by resolution of the Board. Our Board currently consists of seven members. The nominated directors for election are: Chairman Dr. Rosenwald; Executive Vice Chairman, Strategic Development Mr. Weiss; and directors Messrs. Hoenlein, Klein, Lobell, Lorenz and Dr. Harvey. For information about each of the nominees and our Board generally, please see "Corporate Governance – Our Board of Directors" beginning on page 6. If elected, the nominees will hold office until the next annual meeting and until a respective successor is elected and has been qualified, or until such director resigns or is removed from office. Management expects that each of the nominees will be available for election, but if any of them is unable to serve at the time the election occurs, your proxy will be voted for the election of another nominee to be designated by a majority of the directors serving on our Board.

**The Board of Directors unanimously recommends a vote "FOR" the election of all of the nominees for director. If a choice is specified on the proxy by the stockholder, the shares will be voted as specified. If no specification is made, the shares will be voted "FOR" all of the nominees. At any meeting of our stockholders in which there is an uncontested director election, the affirmative vote of a majority of the shares of stock cast by the holders of shares of our common stock present or represented at the Annual Meeting is required for the election of each of the nominees for director.**

[**Table of Contents**](#TOC)

#### PROPOSAL TWO: RATIFICATION OF APPOINTMENT OF KPMG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
The Board is submitting the selection of KPMG LLP as our independent registered public accounting firm to the stockholders for ratification at our Annual Meeting. Stockholder ratification of our independent registered public accounting firm is not required by our Fourth Amended and Restated Bylaws or otherwise. If KPMG LLP is not ratified as our independent registered public accounting firm by a majority of the shares present or represented by proxy, the Audit Committee will review its future selection of independent registered public accounting firm. KPMG LLP will still serve as our independent registered public accounting firm for the year ending December 31, 2026, if its appointment is not ratified by our stockholders.

**The Board of Directors unanimously recommends a vote "FOR" ratification of the appointment of KPMG LLP as the company's independent registered public accounting firm for the year ending December 31, 2026. The affirmative vote of the majority of votes present or represented at the meeting is required for the ratification of the appointment of KPMG LLP.**

[**Table of Contents**](#TOC)

#### ADDITIONAL INFORMATION

#### Householding of Annual Meeting Materials
Some banks, brokers and other nominee record holders may be participating in the practice of "householding" proxy statements and annual reports. This means that only one copy of the Internet Notice and, if applicable, a single set of the proxy statement and 2025 Annual Report, may have been sent to multiple stockholders in your household. We will promptly deliver a separate copy of any document to you if you contact us at: Fortress Biotech, Inc., 1111 Kane Concourse, Suite 301, Bay Harbor Islands, FL 33154, Attn: Sam Berry. You may also contact us at (781) 652-4500.

If you want to receive separate copies of the Internet Notice, or proxy statement and annual report in the future, or if you are receiving multiple copies and would like to receive only one copy for your household, you should contact your bank, broker, or other nominee record holder, or you may contact us at the above address or phone number.

#### Stockholder Proposals for Our 2027 Annual Meeting
Only proper proposals under Rule 14a-8 of the Exchange Act which are timely received will be included in the proxy materials for our next annual meeting. In order to be considered timely, such proposal must be received by our General Counsel and Corporate Secretary, Sam Berry, at 1111 Kane Concourse Suite 301, Bay Harbor Islands, FL 33154, no later than December 29, 2026. We suggest that stockholders submit any stockholder proposal by certified mail, return receipt requested.

Our Fourth Amended and Restated Bylaws require stockholders to provide advance notice to the Company of any stockholder director nomination(s) and any other matter a stockholder wishes to present for action at an annual meeting of stockholders (other than matters to be included in our proxy statement, which are discussed in the previous paragraph). In order to properly bring business before an annual meeting, our Fourth Amended and Restated Bylaws require, among other things, that the stockholder submit written notice thereof complying with our Fourth Amended and Restated Bylaws to Sam Berry, our General Counsel and Corporate Secretary, at the above address, not less than 45 days nor more than 75 days prior to the anniversary of the preceding year's annual meeting. Therefore, the Company must receive notice of a stockholder proposal submitted other than pursuant to Rule 14a-8 (as discussed above) no sooner than April 5, 2027, and no later than May 3, 2027. If a stockholder fails to provide timely notice of a proposal to be presented at our 2027 Annual Meeting of Stockholders, the proxy designated by our Board will have discretionary authority to vote on any such proposal that may come before the meeting.

In addition to satisfying the foregoing requirements under the Company's bylaws, to comply with the universal proxy rules, shareholders who intend to solicit proxies in support of director nominees other than the Company's nominees must provide notice that sets forth the information required by Rule 14a-19 under the Exchange Act no later than April 18, 2027.

#### Other Matters
Our Board does not know of any other matters that may come before the meeting. However, if any other matters are properly presented to the meeting, it is the intention of the person named in the accompanying proxy card to vote, or otherwise act, in accordance with their judgment on such matters.

[**Table of Contents**](#TOC)

#### Solicitation of Proxies
We will bear the cost of solicitation of proxies. In addition to the solicitation of proxies by mail, our officers and employees may solicit proxies in person or by telephone. We may reimburse brokers or persons holding stock in their names, or in the names of their nominees, for their expenses in sending proxies and proxy material to beneficial owners.

#### Incorporation of Information by Reference
The Audit Committee Report contained in this proxy statement is not deemed filed with the SEC and shall not be deemed incorporated by reference into any prior or future filings made by us under the Securities Act of 1933, as amended or the Exchange Act, except to the extent that we specifically incorporate such information by reference. Our Annual Report on Form 10-K for the year ended December 31, 2025, delivered to you together with this proxy statement, is hereby incorporated by reference.

---

| | |
|:---|:---|
| &nbsp;&nbsp;![GRAPHIC](fbio-20260617xdef14a_bg001.jpg) | &nbsp;&nbsp;Signature [PLEASE SIGN WITHIN BOX] Date Signature (Joint Owners) Date TO VOTE, MARK BLOCKS BELOW IN BLUE OR BLACK INK AS FOLLOWS: KEEP THIS PORTION FOR YOUR RECORDS DETACH AND RETURN THIS PORTION ONLY THIS PROXY CARD IS VALID ONLY WHEN SIGNED AND DATED. V93529-P50357 For Against Abstain ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! FORTRESS BIOTECH, INC. Nominees: 2. Ratification of the appointment of KPMG LLP as Fortress Biotech, Inc.'s independent registered public accounting firm for the fiscal year ending December 31, 2026. Please sign exactly as your name(s) appear(s) hereon. When signing as attorney, executor, administrator, or other fiduciary, please give full title as such. Joint owners should each sign personally. All holders must sign. If a corporation or partnership, please sign in full corporate or partnership name by authorized officer. 1. Election of Directors The Board of Directors recommends you vote FOR each of the following nominees in Proposal 1 (Election of Directors): The Board of Directors recommends you vote FOR Proposal 2: For Against Abstain 1a. Lindsay A. Rosenwald, M.D. 1b. Michael S. Weiss 1c. Jimmie Harvey, Jr., M.D. 1d. Malcolm Hoenlein 1e. Dov Klein, CPA 1f. J. Jay Lobell 1g. Kevin L. Lorenz, J.D. FORTRESS BIOTECH, INC. ATTN: DAVID JIN 1111 KANE CONCOURSE SUITE 301 BAY HARBOR ISLANDS, FL 33154 VOTE BY INTERNET Before The Meeting - Go to www.proxyvote.com or scan the QR Barcode above Use the Internet to transmit your voting instructions and for electronic delivery of information up until 11:59 P.M. Eastern Time on June 16, 2026. Have your proxy card in hand when you access the web site and follow the instructions to obtain your records and to create an electronic voting instruction form. During The Meeting - Go to www.virtualshareholdermeeting.com/FBIO2026 You may attend the meeting via the Internet and vote during the meeting. Have the information that is printed in the box marked by the arrow available and follow the instructions. VOTE BY PHONE - 1-800-690-6903 Use any touch-tone telephone to transmit your voting instructions up until 11:59 P.M. Eastern Time on June 16, 2026. Have your proxy card in hand when you call and then follow the instructions. VOTE BY MAIL Mark, sign and date your proxy card and return it in the postage-paid envelope we have provided or return it to Vote Processing, c/o Broadridge, 51 Mercedes Way, Edgewood, NY 11717. ! ! ! SCAN TO VIEW MATERIALS & VOTEw |

---

---

| | |
|:---|:---|
| &nbsp;&nbsp;![GRAPHIC](fbio-20260617xdef14a_bg002.jpg) | &nbsp;&nbsp;V93530-P50357 Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting of Stockholders: The Notice of Annual Meeting of Stockholders and Proxy Statement, and 2025 Annual Report on Form 10-K of Fortress Biotech, Inc. are available at www.proxyvote.com. FORTRESS BIOTECH, INC. Proxy for Annual Meeting of Stockholders June 17, 2026 10:00 AM EDT This proxy is solicited by the Board of Directors The undersigned stockholder of Fortress Biotech, Inc. acknowledges receipt of the Notice of Annual Meeting of Stockholders and Proxy Statement, each dated on or about April 28, 2026. The undersigned stockholder also appoints Lindsay A. Rosenwald, M.D. and David Jin, or either of them, with full power of substitution and power to act alone, as proxy to represent and to vote, as designated on the reverse side of this ballot, all of the shares of Common Stock of Fortress Biotech, Inc. that the stockholder is entitled to vote at the Annual Meeting of Stockholders to be held at 10:00 AM EDT on June 17, 2026, via webcast only at www.virtualshareholdermeeting.com/FBIO2026, and any adjournment or postponement thereof. The undersigned hereby also authorizes the proxy, in his or her discretion, to vote (a) for the election of a person to the Board of Directors if any nominee named herein becomes unable to serve or for good cause will not serve, (b) on any matter that the Board of Directors did not know would be presented at the Annual Meeting a reasonable time before the proxy solicitation was made, and (c) on such other business as may properly come before the Annual Meeting or any adjournment or postponement thereof. This proxy when properly executed will be voted as directed herein by the undersigned stockholder. If no direction is made, this proxy will be voted in accordance with the Board of Directors' recommendations and, accordingly, will be voted FOR each of the Board of Directors' nominees for director specified in proposal 1 and FOR proposal 2. Continued and to be signed on reverse side |

---