# EDGAR Filing Document

**Accession Number:** 0001842296
**File Stem:** 0001842296-26-000006
**Filing Date:** 2026-4
**Character Count:** 56560
**Document Hash:** 097f63953b3054fb3efde3bfef6a2822
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001842296-26-000006.hdr.sgml**: 20260413

**ACCESSION NUMBER**: 0001842296-26-000006

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260413

**DATE AS OF CHANGE**: 20260413

**EFFECTIVENESS DATE**: 20260413

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** E Fund Management Co., Ltd.
- **CENTRAL INDEX KEY:** 0001842296

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** F4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-20539
- **FILM NUMBER:** 26856371

**BUSINESS ADDRESS:**
- **STREET 1:** 40-43/F, BANK OF GUANGZHOU SQUARE,
- **STREET 2:** NO.30 EAST ZHUJIANG ROAD,TIANHE DISTRICT
- **CITY:** GUANGZHOU
- **STATE:** F4
- **ZIP:** 510620
- **BUSINESS PHONE:** 8602-85102583

**MAIL ADDRESS:**
- **STREET 1:** 40-43/F, BANK OF GUANGZHOU SQUARE,
- **STREET 2:** NO.30 EAST ZHUJIANG ROAD,TIANHE DISTRICT
- **CITY:** GUANGZHOU
- **STATE:** F4
- **ZIP:** 510620

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 03-31-2026

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** E Fund Management Co. Ltd.<br>**Address:** 40-43/F BANK OF GUANGZHOU SQUARE<br>NO.30 EAST ZHUJIANG ROADTIANHE DISTRICT<br>GUANGZHOU, F4 510620

**Form 13F File Number:** 028-20539

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Wuwei Tang<br>**Title:** Compliance Manager<br>**Phone:** 8602085102583

**Signature, Place, and Date of Signing:**

Wuwei Tang  Guangzhou, F4  04-13-2026<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 489

**Form 13F Information Table Value Total:** $3365841983

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| AGILENT TECHNOLOGIES INC | COM | 00846U101 | BBG000C2V3D6 | 425602 | 3734 | SH |  | DFND |  | 3734 | 0 | 0 |
| APPLE INC | COM | 037833100 | BBG000B9XRY4 | 181728360 | 716058 | SH |  | DFND |  | 716058 | 0 | 0 |
| ABBVIE INC | COM | 00287Y109 | BBG0025Y4RY4 | 4815881 | 22143 | SH |  | DFND |  | 22143 | 0 | 0 |
| AIRBNB INC | COM CL A | 009066101 | BBG001Y2XS07 | 1889528 | 14963 | SH |  | DFND |  | 14963 | 0 | 0 |
| ABSCI CORPORATION | COM | 00091E109 | BBG011N54CJ8 | 90870 | 30290 | SH |  | SOLE |  | 30290 | 0 | 0 |
| ABBOTT LABORATORIES | COM | 002824100 | BBG000B9ZXB4 | 2125269 | 20700 | SH |  | DFND |  | 20700 | 0 | 0 |
| ARBUTUS BIOPHARMA CORP | COM | 03879J100 | BBG000RR8V85 | 69493 | 15443 | SH |  | SOLE |  | 15443 | 0 | 0 |
| ABIVAX SA | SPONSORED ADS | 00370M103 | BBG01JLQNZ03 | 1529058 | 13732 | SH |  | DFND |  | 13732 | 0 | 0 |
| ACADIA PHARMACEUTICALS INC | COM | 004225108 | BBG000BHG9K0 | 508352 | 22837 | SH |  | SOLE |  | 22837 | 0 | 0 |
| ARCELLX INC | COMMON STOCK | 03940C100 | BBG00QHJM4S9 | 583745 | 5084 | SH |  | DFND |  | 5084 | 0 | 0 |
| ACCENTURE PLC IRELAND | SHS CLASS A | G1151C101 | BBG000D9D830 | 3354472 | 16917 | SH |  | DFND |  | 16917 | 0 | 0 |
| ADOBE INC | COM | 00724F101 | BBG000BB5006 | 5918755 | 24349 | SH |  | DFND |  | 24349 | 0 | 0 |
| ANALOG DEVICES INC | COM | 032654105 | BBG000BB6G37 | 9347271 | 29381 | SH |  | DFND |  | 29381 | 0 | 0 |
| ADMA BIOLOGICS INC | COM | 000899104 | BBG002NCK5M5 | 296402 | 32897 | SH |  | SOLE |  | 32897 | 0 | 0 |
| AUTOMATIC DATA PROCESSING IN | COM | 053015103 | BBG000JG0547 | 2905880 | 14302 | SH |  | DFND |  | 14302 | 0 | 0 |
| AUTODESK INC | COM | 052769106 | BBG000BM7HL0 | 3025298 | 12637 | SH |  | DFND |  | 12637 | 0 | 0 |
| AGNICO EAGLE MINES LTD | COM | 008474108 | BBG000DLVDK3 | 3570012 | 17588 | SH |  | SOLE |  | 17588 | 0 | 0 |
| AMERICAN ELEC PWR CO INC | COM | 025537101 | BBG000BB9KF2 | 2517129 | 19203 | SH |  | DFND |  | 19203 | 0 | 0 |
| FIRST MAJESTIC SILVER CORP | COM | 32076V103 | BBG000CH7WB8 | 382473 | 17806 | SH |  | SOLE |  | 17806 | 0 | 0 |
| ALAMOS GOLD INC | COM CL A | 011532108 | BBG009HT6BL4 | 681306 | 15317 | SH |  | SOLE |  | 15317 | 0 | 0 |
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 | BBG000QY4ZD0 | 436914 | 12915 | SH |  | SOLE |  | 12915 | 0 | 0 |
| GALLAGHER ARTHUR J  CO | COM | 363576109 | BBG000BBHXQ3 | 214848 | 992 | SH |  | DFND |  | 992 | 0 | 0 |
| AKAMAI TECHNOLOGIES INC | COM | 00971T101 | BBG000BJQWD2 | 441828 | 3847 | SH |  | SOLE |  | 3847 | 0 | 0 |
| AKEBIA THREAPEUTICS INC | COM | 00972D105 | BBG000R33R00 | 57155 | 41119 | SH |  | SOLE |  | 41119 | 0 | 0 |
| ALBEMARLE CORP | COM | 012653101 | BBG000BJ26K7 | 304304 | 1695 | SH |  | DFND |  | 1695 | 0 | 0 |
| ALIGN TECHNOLOGY INC | COM | 016255101 | BBG000BRNLL2 | 344746 | 2011 | SH |  | DFND |  | 2011 | 0 | 0 |
| ALKERMES PLC | SHS | G01767105 | BBG000C9F2F9 | 739731 | 20920 | SH |  | DFND |  | 20920 | 0 | 0 |
| ALLOGENE THERAPEUTICS INC | COM | 019770106 | BBG00KHRRDX3 | 86600 | 35492 | SH |  | SOLE |  | 35492 | 0 | 0 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | BBG000BFGNJ5 | 2009704 | 6074 | SH |  | DFND |  | 6074 | 0 | 0 |
| ALTIMMUNE INC | COM NEW | 02155H200 | BBG000FXML90 | 89542 | 29072 | SH |  | SOLE |  | 29072 | 0 | 0 |
| APPLIED MATLS INC | COM | 038222105 | BBG000BBPFB9 | 18077957 | 52892 | SH |  | DFND |  | 52892 | 0 | 0 |
| ADVANCED MICRO DEVICES INC | COM | 007903107 | BBG000BBQCY0 | 30099706 | 147961 | SH |  | DFND |  | 147961 | 0 | 0 |
| AMGEN INC | COM | 031162100 | BBG000BBS2Y0 | 7574627 | 21528 | SH |  | DFND |  | 21528 | 0 | 0 |
| AMERICAN TOWER CORP | COM | 03027X100 | BBG000B9XYV2 | 293732 | 1702 | SH |  | DFND |  | 1702 | 0 | 0 |
| AMAZON COM INC | COM | 023135106 | BBG000BVPV84 | 48152232 | 231201 | SH |  | DFND |  | 231201 | 0 | 0 |
| ARISTA NETWORKS INC | COM SHS | 040413205 | BBG000N2HDY5 | 3564671 | 29033 | SH |  | DFND |  | 29033 | 0 | 0 |
| ANNEXON INC | COM | 03589W102 | BBG007QVDFG2 | 141558 | 25552 | SH |  | SOLE |  | 25552 | 0 | 0 |
| AON PLC | SHS CL A | G0403H108 | BBG00SSQFPK6 | 256610 | 795 | SH |  | DFND |  | 795 | 0 | 0 |
| AIR PRODUCTS AND CHEMICALS I | COM | 009158106 | BBG000BC4JJ4 | 230940 | 795 | SH |  | DFND |  | 795 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 | BBG01H51WYQ5 | 639103 | 7593 | SH |  | SOLE |  | 7593 | 0 | 0 |
| AMPHENOL CORP | CL A | 032095101 | BBG000B9YJ35 | 4383334 | 34692 | SH |  | DFND |  | 34692 | 0 | 0 |
| AGORA INC | ADS | 00851L103 | BBG00V9VKFB5 | 193125 | 54555 | SH |  | SOLE |  | 54555 | 0 | 0 |
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | BBG007KGRPY4 | 912658 | 22686 | SH |  | SOLE |  | 22686 | 0 | 0 |
| APPLOVIN CORP | COM CL A | 03831W108 | BBG006HFPX77 | 6999228 | 17586 | SH |  | DFND |  | 17586 | 0 | 0 |
| ARDELYX INC | COM | 039697107 | BBG001WH4DQ3 | 307095 | 51268 | SH |  | SOLE |  | 51268 | 0 | 0 |
| ARM HOLDINGS PLC | SPONSORED ADS | 042068205 | BBG01J1GXZF0 | 8538848 | 56444 | SH |  | DFND |  | 56444 | 0 | 0 |
| ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 | BBG00QN8K4M4 | 542045 | 23007 | SH |  | SOLE |  | 23007 | 0 | 0 |
| ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | BBG000BRVKH0 | 627000 | 10000 | SH |  | DFND |  | 10000 | 0 | 0 |
| ASML HLDG NV | N Y REGISTRY SHS | N07059210 | BBG000K6MRN4 | 45285977 | 34286 | SH |  | DFND |  | 34286 | 0 | 0 |
| ASE TECHNOLOGY HLDG CO LTD | SPONSORED ADS | 00215W100 | BBG00KLHL9W6 | 1250351 | 57673 | SH |  | DFND |  | 57673 | 0 | 0 |
| ATOUR LIFESTYLE HLDGS LTD | SPONSORED ADS | 04965M106 | BBG011C6KJG8 | 16564500 | 450000 | SH |  | SOLE |  | 450000 | 0 | 0 |
| AUTOHOME INC | SP ADS RP CL A | 05278C107 | BBG005JYTDQ5 | 4695354 | 270314 | SH |  | DFND |  | 270314 | 0 | 0 |
| ANGLOGOLD ASHANTI PLC | COM SHS | G0378L100 | BBG01HGVLP51 | 1727848 | 17747 | SH |  | SOLE |  | 17747 | 0 | 0 |
| ARRIVENT BIOPHARMA INC | COM | 04272N102 | BBG011N37VQ0 | 2167496 | 93953 | SH |  | SOLE |  | 93953 | 0 | 0 |
| BROADCOM INC | COM | 11135F101 | BBG00KHY5S69 | 71097233 | 229709 | SH |  | DFND |  | 229709 | 0 | 0 |
| ANAVEX LIFE SCIENCES CORP | COM NEW | 032797300 | BBG000C9K8K4 | 55475 | 18070 | SH |  | SOLE |  | 18070 | 0 | 0 |
| AXON ENTERPRISE INC | COM | 05464C101 | BBG000BHJWG1 | 1213339 | 2857 | SH |  | DFND |  | 2857 | 0 | 0 |
| AMERICAN EXPRESS CO | COM | 025816109 | BBG000BCQZS4 | 604658 | 1999 | SH |  | DFND |  | 1999 | 0 | 0 |
| AXT INC | COM | 00246W103 | BBG000BHZ0N5 | 71949729 | 1262719 | SH |  | DFND |  | 1262719 | 0 | 0 |
| AUTOZONE INC | COM | 053332102 | BBG000C7LMS8 | 209422 | 62 | SH |  | DFND |  | 62 | 0 | 0 |
| BARRICK MNG CORP | COM SHS | 06849F108 | BBG000BB07P9 | 2387586 | 58436 | SH |  | SOLE |  | 58436 | 0 | 0 |
| BOEING CO | COM | 097023105 | BBG000BCSST7 | 574998 | 2889 | SH |  | DFND |  | 2889 | 0 | 0 |
| BANK AMERICA CORP | COM | 060505104 | BBG000BCTLF6 | 3401434 | 69773 | SH |  | DFND |  | 69773 | 0 | 0 |
| BAXTER INTL INC | COM | 071813109 | BBG000BCVJ77 | 322879 | 19219 | SH |  | DFND |  | 19219 | 0 | 0 |
| BRIDGEBIO PHARMA INC | COM | 10806X102 | BBG00P9KDZK6 | 606110 | 8162 | SH |  | DFND |  | 8162 | 0 | 0 |
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | BBG000BLYWX6 | 423945 | 44532 | SH |  | SOLE |  | 44532 | 0 | 0 |
| BECTON DICKINSON  CO | COM | 075887109 | BBG000BCZYD3 | 462727 | 2943 | SH |  | DFND |  | 2943 | 0 | 0 |
| BLOOM ENERGY CORP | COM CL A | 093712107 | BBG000N7KBZ3 | 11198113 | 82649 | SH |  | SOLE |  | 82649 | 0 | 0 |
| BEAM THERAPEUTICS INC | COM | 07373V105 | BBG00KXC8646 | 518064 | 21740 | SH |  | SOLE |  | 21740 | 0 | 0 |
| BIOHAVEN LTD | COM | G1110E107 | BBG017BXV3Q9 | 217524 | 25712 | SH |  | SOLE |  | 25712 | 0 | 0 |
| BIOGEN INC | COM | 09062X103 | BBG000C17X76 | 954966 | 5209 | SH |  | DFND |  | 5209 | 0 | 0 |
| BANK NEW YORK MELLON CORP | COM | 064058100 | BBG000BD8PN9 | 313302 | 2641 | SH |  | DFND |  | 2641 | 0 | 0 |
| BOOKING HOLDINGS INC | COM | 09857L108 | BBG000BLBVN4 | 4757662 | 1130 | SH |  | DFND |  | 1130 | 0 | 0 |
| BAKER HUGHES COMPANY | CL A | 05722G100 | BBG00GBVBK51 | 2148288 | 35189 | SH |  | DFND |  | 35189 | 0 | 0 |
| BLACKROCK INC | COM | 09290D101 | BBG01PSW2WN4 | 507783 | 528 | SH |  | DFND |  | 528 | 0 | 0 |
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | BBG000CZWZ05 | 544338 | 9636 | SH |  | DFND |  | 9636 | 0 | 0 |
| BRISTOL-MYERS SQUIBB CO | COM | 110122108 | BBG000DQLV23 | 782628 | 12904 | SH |  | DFND |  | 12904 | 0 | 0 |
| UNITED STS BRENT OIL FD LP | UNIT | 91167Q100 | BBG000QZBM11 | 15260358 | 293412 | SH |  | SOLE |  | 293412 | 0 | 0 |
| BERKSHIRE HATHAWAY INC DEL | CL B NEW | 084670702 | BBG000DWG505 | 7609696 | 15880 | SH |  | DFND |  | 15880 | 0 | 0 |
| BOSTON SCIENTIFIC CORP | COM | 101137107 | BBG000C0LW92 | 618401 | 9855 | SH |  | DFND |  | 9855 | 0 | 0 |
| B2GOLD CORP | COM | 11777Q209 | BBG000V9KFD5 | 209204 | 46058 | SH |  | SOLE |  | 46058 | 0 | 0 |
| BLACKSTONE INC | COM | 09260D107 | BBG000BH0106 | 316797 | 2755 | SH |  | DFND |  | 2755 | 0 | 0 |
| KANZHUN LIMITED | SPONSORED ADS | 48553T106 | BBG01163M5L4 | 23289642 | 1739331 | SH |  | DFND |  | 1739331 | 0 | 0 |
| CITIGROUP INC | COM NEW | 172967424 | BBG000FY4S11 | 724009 | 6384 | SH |  | DFND |  | 6384 | 0 | 0 |
| CARDINAL HEALTH INC | COM | 14149Y108 | BBG000D898T9 | 495733 | 2346 | SH |  | DFND |  | 2346 | 0 | 0 |
| CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | BBG000DZMK99 | 238275 | 7838 | SH |  | SOLE |  | 7838 | 0 | 0 |
| CATERPILLAR INC | COM | 149123101 | BBG000BF0K17 | 3482790 | 4916 | SH |  | DFND |  | 4916 | 0 | 0 |
| PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | BBG000BG5HT7 | 48651 | 11667 | SH |  | SOLE |  | 11667 | 0 | 0 |
| CHUBB LTD SWITZ | COM | H1467J104 | BBG000BR14K5 | 441310 | 1354 | SH |  | DFND |  | 1354 | 0 | 0 |
| CBOE GLOBAL MKTS INC | COM | 12503M108 | BBG000QH56C1 | 403616 | 1436 | SH |  | DFND |  | 1436 | 0 | 0 |
| COCA-COLA EUROPACIFIC PARTNE | SHS | G25839104 | BBG00B6BFWH9 | 1324598 | 14609 | SH |  | DFND |  | 14609 | 0 | 0 |
| CARNIVAL CORP | COMMON STOCK | 143658300 | BBG000BF6LY3 | 1379430 | 53301 | SH |  | DFND |  | 53301 | 0 | 0 |
| COEUR MNG INC | COM NEW | 192108504 | BBG000BF8TF5 | 744080 | 39642 | SH |  | SOLE |  | 39642 | 0 | 0 |
| CADENCE DESIGN SYSTEM INC | COM | 127387108 | BBG000C13CD9 | 4520111 | 16267 | SH |  | DFND |  | 16267 | 0 | 0 |
| CDW CORP | COM | 12514G108 | BBG001P63B80 | 426353 | 3523 | SH |  | SOLE |  | 3523 | 0 | 0 |
| CONSTELLATION ENERGY CORP | COM | 21037T109 | BBG014KFRNP7 | 3528045 | 12634 | SH |  | DFND |  | 12634 | 0 | 0 |
| CELCUITY INC | COM | 15102K100 | BBG00HKBW045 | 5288906 | 46337 | SH |  | DFND |  | 46337 | 0 | 0 |
| CG ONCOLOGY INC | COM | 156944100 | BBG00YHKK4Q3 | 594162 | 8779 | SH |  | DFND |  | 8779 | 0 | 0 |
| CHARTER COMMUNICATIONS INC | CL A | 16119P108 | BBG000VPGNR2 | 941452 | 4361 | SH |  | DFND |  | 4361 | 0 | 0 |
| THE CIGNA GROUP | COM | 125523100 | BBG00KXRCDP0 | 571912 | 2144 | SH |  | DFND |  | 2144 | 0 | 0 |
| CIENA CORP | COM NEW | 171779309 | BBG000BP1152 | 18616017 | 47951 | SH |  | DFND |  | 47951 | 0 | 0 |
| COLGATE PALMOLIVE CO | COM | 194162103 | BBG000BFQYY3 | 252195 | 2959 | SH |  | DFND |  | 2959 | 0 | 0 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | BBG000FW8LZ9 | 259406 | 8178 | SH |  | SOLE |  | 8178 | 0 | 0 |
| CELESTICA INC | COM | 15101Q207 | BBG000BPS2C3 | 309848 | 1100 | SH |  | SOLE |  | 1100 | 0 | 0 |
| COMCAST CORP NEW | CL A | 20030N101 | BBG000BFT2L4 | 3692709 | 128621 | SH |  | DFND |  | 128621 | 0 | 0 |
| CME GROUP INC | COM | 12572Q105 | BBG000BHLYP4 | 380411 | 1288 | SH |  | DFND |  | 1288 | 0 | 0 |
| CUMMINS INC | COM | 231021106 | BBG000BGPTV6 | 575144 | 1069 | SH |  | DFND |  | 1069 | 0 | 0 |
| COMPASS THERAPEUTICS INC | COM | 20454B104 | BBG00LPXKF25 | 130250 | 24622 | SH |  | SOLE |  | 24622 | 0 | 0 |
| CENTENE CORP DEL | COM | 15135B101 | BBG000BDXCJ5 | 341347 | 10426 | SH |  | DFND |  | 10426 | 0 | 0 |
| CAPITAL ONE FINL CORP | COM | 14040H105 | BBG000BGKTF9 | 424514 | 2327 | SH |  | DFND |  | 2327 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 | BBG007DHZQR7 | 619843 | 16104 | SH |  | DFND |  | 16104 | 0 | 0 |
| COHERENT CORP | COM | 19247G107 | BBG000BLW102 | 9080089 | 38118 | SH |  | SOLE |  | 38118 | 0 | 0 |
| COINBASE GLOBAL INC | COM CL A | 19260Q107 | BBG00ZGF7771 | 330711 | 1894 | SH |  | DFND |  | 1894 | 0 | 0 |
| COOPER COS INC | COM | 216648501 | BBG000BG3445 | 351137 | 4911 | SH |  | SOLE |  | 4911 | 0 | 0 |
| CONOCOPHILLIPS | COM | 20825C104 | BBG000BQQH30 | 605220 | 4585 | SH |  | DFND |  | 4585 | 0 | 0 |
| CENCORA INC | COM | 03073E105 | BBG000MDCQC2 | 507650 | 1616 | SH |  | DFND |  | 1616 | 0 | 0 |
| COSTCO WHOLESALE CORPORATION | COM | 22160K105 | BBG000F6H8W8 | 18918220 | 18986 | SH |  | DFND |  | 18986 | 0 | 0 |
| COPART INC | COM | 217204106 | BBG000BM9RH1 | 1136768 | 34240 | SH |  | DFND |  | 34240 | 0 | 0 |
| CATALYST PHARMACEUTICALS INC | COM | 14888U101 | BBG000GZDC67 | 375783 | 15177 | SH |  | SOLE |  | 15177 | 0 | 0 |
| CRH PLC | ORD | G25508105 | BBG000D3JXM1 | 267951 | 2549 | SH |  | DFND |  | 2549 | 0 | 0 |
| CHARLES RIV LABS INTL INC | COM | 159864107 | BBG000BG5BL8 | 346035 | 2006 | SH |  | SOLE |  | 2006 | 0 | 0 |
| SALESFORCE INC | COM | 79466L302 | BBG000BN2DC2 | 4805446 | 25743 | SH |  | DFND |  | 25743 | 0 | 0 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | BBG00DBBGRX1 | 552335 | 11611 | SH |  | DFND |  | 11611 | 0 | 0 |
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | BBG009F0TGH8 | 207102 | 14156 | SH |  | SOLE |  | 14156 | 0 | 0 |
| CROWDSTRIKE HLDGS INC | CL A | 22788C105 | BBG00BLYKS03 | 5835458 | 14947 | SH |  | DFND |  | 14947 | 0 | 0 |
| CISCO SYS INC | COM | 17275R102 | BBG000C3J3C9 | 20339831 | 262145 | SH |  | DFND |  | 262145 | 0 | 0 |
| COSTAR GROUP INC | COM | 22160N109 | BBG000D7JKW9 | 601671 | 14915 | SH |  | DFND |  | 14915 | 0 | 0 |
| CSX CORP | COM | 126408103 | BBG000BGJRC8 | 2712912 | 66088 | SH |  | DFND |  | 66088 | 0 | 0 |
| CINTAS CORP | COM | 172908105 | BBG000H3YXF8 | 2361702 | 13963 | SH |  | DFND |  | 13963 | 0 | 0 |
| CYTOMX THERAPEUTICS INC. | COM | 23284F105 | BBG001J472L3 | 141691 | 30147 | SH |  | SOLE |  | 30147 | 0 | 0 |
| COGNIZANT TECHNOLOGY SOLUTIO | CL A | 192446102 | BBG000BBDV81 | 1733322 | 28253 | SH |  | DFND |  | 28253 | 0 | 0 |
| CORTEVA INC | COM | 22052L104 | BBG00BN969C1 | 216306 | 2584 | SH |  | DFND |  | 2584 | 0 | 0 |
| CVS HEALTH CORP | COM | 126650100 | BBG000BGRY34 | 632447 | 8806 | SH |  | DFND |  | 8806 | 0 | 0 |
| CHEVRON CORPORATION | COM | 166764100 | BBG000K4ND22 | 4058344 | 19615 | SH |  | DFND |  | 19615 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 | BBG000F0R4N9 | 603076 | 9150 | SH |  | DFND |  | 9150 | 0 | 0 |
| DOORDASH INC | CL A | 25809K105 | BBG005D7QCJ3 | 2161409 | 14395 | SH |  | DFND |  | 14395 | 0 | 0 |
| INVESCO DB MULTI-SECTOR COMM | OIL FD | 46140H403 | BBG000QNH3T4 | 19271407 | 979736 | SH |  | SOLE |  | 979736 | 0 | 0 |
| DATADOG INC | CL A COM | 23804L103 | BBG003NJHZT9 | 2288282 | 19384 | SH |  | DFND |  | 19384 | 0 | 0 |
| DEERE  CO | COM | 244199105 | BBG000BH1NH9 | 519926 | 923 | SH |  | DFND |  | 923 | 0 | 0 |
| DELL TECHNOLOGIES INC | CL C | 24703L202 | BBG00DW3SZS1 | 1338972 | 8158 | SH |  | DFND |  | 8158 | 0 | 0 |
| QUEST DIAGNOSTICS INC | COM | 74834L100 | BBG000BN84F3 | 383729 | 1958 | SH |  | SOLE |  | 1958 | 0 | 0 |
| DANAHER CORP DEL | COM | 235851102 | BBG000BH3JF8 | 747972 | 3945 | SH |  | DFND |  | 3945 | 0 | 0 |
| DISNEY WALT CO | COM | 254687106 | BBG000BH4R78 | 626373 | 6499 | SH |  | DFND |  | 6499 | 0 | 0 |
| DIGITAL RLTY TR INC | COM | 253868103 | BBG000Q5ZRM7 | 207602 | 1152 | SH |  | DFND |  | 1152 | 0 | 0 |
| DENALI THERAPEUTICS INC | COM | 24823R105 | BBG008P7F869 | 363686 | 18942 | SH |  | SOLE |  | 18942 | 0 | 0 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 | BBG00FB2NPZ0 | 329386 | 3925 | SH |  | SOLE |  | 3925 | 0 | 0 |
| DIANA SHIPPING INC | COM | Y2066G104 | BBG000BV1NV2 | 1267358 | 506943 | SH |  | SOLE |  | 506943 | 0 | 0 |
| DUKE ENERGY CORP NEW | COM NEW | 26441C204 | BBG000BHGDH5 | 670805 | 5123 | SH |  | DFND |  | 5123 | 0 | 0 |
| DAVITA INC | COM | 23918K108 | BBG000MQ1SN9 | 328282 | 2136 | SH |  | SOLE |  | 2136 | 0 | 0 |
| DEXCOM INC | COM | 252131107 | BBG000QTF8K1 | 1152945 | 18359 | SH |  | DFND |  | 18359 | 0 | 0 |
| DYNE THERAPEUTICS INC | COM | 26818M108 | BBG00NSGPJD0 | 417008 | 23001 | SH |  | SOLE |  | 23001 | 0 | 0 |
| ELECTRONIC ARTS INC | COM | 285512109 | BBG000BP0KQ8 | 1797318 | 8816 | SH |  | DFND |  | 8816 | 0 | 0 |
| EMERGENT BIOSOLUTIONS INC | COM | 29089Q105 | BBG000GW06J7 | 88893 | 10710 | SH |  | SOLE |  | 10710 | 0 | 0 |
| ECOLAB INC | COM | 278865100 | BBG000BHKYH4 | 254049 | 955 | SH |  | DFND |  | 955 | 0 | 0 |
| LAUDER ESTEE COS INC | CL A | 518439104 | BBG000FKJRC5 | 632653 | 8815 | SH |  | DFND |  | 8815 | 0 | 0 |
| WISDOMTREE TR | EM LCL DEBT FD | 97717X867 | BBG0014GXD84 | 248172 | 7229 | SH |  | SOLE |  | 7229 | 0 | 0 |
| ELEVANCE HEALTH INC FORMERLY | COM | 036752103 | BBG000BCG930 | 561788 | 1919 | SH |  | DFND |  | 1919 | 0 | 0 |
| EMERSON ELEC CO | COM | 291011104 | BBG000BHX7N2 | 270557 | 2065 | SH |  | DFND |  | 2065 | 0 | 0 |
| EOG RES INC | COM | 26875P101 | BBG000BZ9223 | 602423 | 4167 | SH |  | DFND |  | 4167 | 0 | 0 |
| EPAM SYS INC | COM | 29414B104 | BBG000MHTV89 | 201069 | 1485 | SH |  | SOLE |  | 1485 | 0 | 0 |
| EQUINIX INC | COM | 29444U700 | BBG000MBDGM6 | 357788 | 365 | SH |  | DFND |  | 365 | 0 | 0 |
| EQUINOX GOLD CORP | COM | 29446Y502 | BBG004XB7MN9 | 398623 | 27608 | SH |  | SOLE |  | 27608 | 0 | 0 |
| ERASCA INC | COM | 29479A108 | BBG00MTSR883 | 527549 | 32605 | SH |  | DFND |  | 32605 | 0 | 0 |
| EATON CORP PLC | SHS | G29183103 | BBG000BJ3PD2 | 520410 | 1455 | SH |  | DFND |  | 1455 | 0 | 0 |
| EVOMMUNE INC | COM SHS | 30054Y107 | BBG00Y79N887 | 5602663 | 243700 | SH |  | SOLE |  | 243700 | 0 | 0 |
| EDWARDS LIFESCIENCES CORP | COM | 28176E108 | BBG000BRXP69 | 460620 | 5752 | SH |  | DFND |  | 5752 | 0 | 0 |
| EXELON CORP | COM | 30161N101 | BBG000J6XT05 | 1789328 | 36502 | SH |  | DFND |  | 36502 | 0 | 0 |
| EXELIXIS INC | COM | 30161Q104 | BBG000BQ4WF8 | 597372 | 13928 | SH |  | DFND |  | 13928 | 0 | 0 |
| EYEPOINT INC | COM NEW | 30233G209 | BBG000F90JX5 | 1218105 | 94500 | SH |  | SOLE |  | 94500 | 0 | 0 |
| FORD MTR CO | COM | 345370860 | BBG000BQPC32 | 161272 | 13975 | SH |  | DFND |  | 13975 | 0 | 0 |
| DIAMONDBACK ENERGY INC | COM | 25278X109 | BBG002PHSYX9 | 2308209 | 11670 | SH |  | DFND |  | 11670 | 0 | 0 |
| FASTENAL CO | COM | 311900104 | BBG000BJ8YN7 | 1887181 | 40672 | SH |  | DFND |  | 40672 | 0 | 0 |
| FREEPORT MCMORAN INC | CL B | 35671D857 | BBG000BJDB15 | 307478 | 5231 | SH |  | DFND |  | 5231 | 0 | 0 |
| FEDEX CORP | COM | 31428X106 | BBG000BJF1Z8 | 281382 | 790 | SH |  | DFND |  | 790 | 0 | 0 |
| FERROVIAL SE | ORD SHS | N3168P101 | BBG01H7CZ9S9 | 1496865 | 23011 | SH |  | DFND |  | 23011 | 0 | 0 |
| F5 INC | COM | 315616102 | BBG000CXYSZ6 | 457431 | 1581 | SH |  | DFND |  | 1581 | 0 | 0 |
| FAIR ISAAC CORP | COM | 303250104 | BBG000DW76Y6 | 693901 | 650 | SH |  | DFND |  | 650 | 0 | 0 |
| FABRINET | SHS | G3323L100 | BBG000HBFQP5 | 2733808 | 5242 | SH |  | SOLE |  | 5242 | 0 | 0 |
| AMICUS THERAPEUTIC | COM | 03152W109 | BBG000PLF6N0 | 585066 | 40461 | SH |  | DFND |  | 40461 | 0 | 0 |
| FIRST SOLAR INC | COM | 336433107 | BBG000BFL116 | 572054 | 2900 | SH |  | DFND |  | 2900 | 0 | 0 |
| FORTINET INC | COM | 34959E109 | BBG000BCMBG4 | 3330254 | 40752 | SH |  | DFND |  | 40752 | 0 | 0 |
| FUTU HLDGS LTD | SPON ADS CL A | 36118L106 | BBG00MYXW4R8 | 35030390 | 256145 | SH |  | DFND |  | 256145 | 0 | 0 |
| GENERAL DYNAMICS CORP | COM | 369550108 | BBG000BK67C7 | 316792 | 923 | SH |  | DFND |  | 923 | 0 | 0 |
| GODADDY INC | CL A | 380237107 | BBG006MDLY05 | 302490 | 3659 | SH |  | SOLE |  | 3659 | 0 | 0 |
| GE AEROSPACE | COM NEW | 369604301 | BBG000BK6MB5 | 3085431 | 10873 | SH |  | DFND |  | 10873 | 0 | 0 |
| GE HEALTHCARE TECHNOLOGIES I | COMMON STOCK | 36266G107 | BBG01BFR8YV1 | 1444028 | 20287 | SH |  | DFND |  | 20287 | 0 | 0 |
| GEN DIGITAL INC | COM | 668771108 | BBG000BH2JM1 | 286461 | 15213 | SH |  | SOLE |  | 15213 | 0 | 0 |
| GERON CORP | COM | 374163103 | BBG000GX1891 | 165494 | 111070 | SH |  | SOLE |  | 111070 | 0 | 0 |
| GE VERNOVA INC | COM | 36828A101 | BBG013G17W31 | 13503763 | 15470 | SH |  | DFND |  | 15470 | 0 | 0 |
| GOLD FIELDS LTD | SPONSORED ADR | 38059T106 | BBG000KHT4K7 | 1487713 | 32769 | SH |  | SOLE |  | 32769 | 0 | 0 |
| GILEAD SCIENCES INC | COM | 375558103 | BBG000CKGBP2 | 7032331 | 50458 | SH |  | DFND |  | 50458 | 0 | 0 |
| SPDR GOLD TR | GOLD SHS | 78463V107 | BBG000CRF6Q8 | 12922900 | 30033 | SH |  | SOLE |  | 30033 | 0 | 0 |
| WORLD GOLD TR | SPDR GLD MINIS | 98149E303 | BBG00L8YYP89 | 13396022 | 144525 | SH |  | SOLE |  | 144525 | 0 | 0 |
| MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | BBG00X2VGZQ3 | 216334 | 13151 | SH |  | SOLE |  | 13151 | 0 | 0 |
| CORNING INC | COM | 219350105 | BBG000BKFZM4 | 93992390 | 691273 | SH |  | DFND |  | 691273 | 0 | 0 |
| GENERAL MTRS CO | COM | 37045V100 | BBG000NDYB67 | 253151 | 3398 | SH |  | DFND |  | 3398 | 0 | 0 |
| ALPHABET INC | CAP STK CL C | 02079K107 | BBG009S3NB30 | 47990531 | 167296 | SH |  | DFND |  | 167296 | 0 | 0 |
| ALPHABET INC | CAP STK CL A | 02079K305 | BBG009S39JX6 | 126128129 | 438615 | SH |  | DFND |  | 438615 | 0 | 0 |
| GRAIL INC | COM | 384747101 | BBG01N6CGW43 | 360055 | 6967 | SH |  | SOLE |  | 6967 | 0 | 0 |
| GOLDMAN SACHS GROUP INC | COM | 38141G104 | BBG000C6CFJ5 | 2619185 | 3096 | SH |  | DFND |  | 3096 | 0 | 0 |
| HALOZYME THERAPEUTICS INC | COM | 40637H109 | BBG000CZ8W54 | 565060 | 8743 | SH |  | DFND |  | 8743 | 0 | 0 |
| HCA HEALTHCARE INC | COM | 40412C101 | BBG000QW7VC1 | 550378 | 1163 | SH |  | DFND |  | 1163 | 0 | 0 |
| HOME DEPOT INC | COM | 437076102 | BBG000BKZB36 | 3374740 | 10261 | SH |  | DFND |  | 10261 | 0 | 0 |
| HILTON WORLDWIDE HLDGS INC | COM | 43300A203 | BBG0058KMH30 | 2590458 | 8519 | SH |  | DFND |  | 8519 | 0 | 0 |
| HARMONY GOLD MNG LTD | SPONSORED ADR | 413216300 | BBG000BX93G1 | 358352 | 23315 | SH |  | SOLE |  | 23315 | 0 | 0 |
| HOLOGIC INC | COM | 436440101 | BBG000C3NTN5 | 370240 | 4898 | SH |  | SOLE |  | 4898 | 0 | 0 |
| HONEYWELL INTL INC | COM | 438516106 | BBG000H556T9 | 5101949 | 22572 | SH |  | DFND |  | 22572 | 0 | 0 |
| ROBINHOOD MKTS INC | COM CL A | 770700102 | BBG008NMBXN8 | 511989 | 7388 | SH |  | DFND |  | 7388 | 0 | 0 |
| HEWLETT PACKARD ENTERPRISE C | COM | 42824C109 | BBG0078W3NQ3 | 863780 | 36278 | SH |  | DFND |  | 36278 | 0 | 0 |
| HP INC | COM | 40434L105 | BBG000KHWT55 | 493255 | 25677 | SH |  | DFND |  | 25677 | 0 | 0 |
| SCHEIN HENRY INC | COM | 806407102 | BBG000BNMMJ3 | 325017 | 4410 | SH |  | SOLE |  | 4410 | 0 | 0 |
| H WORLD GROUP LTD | SPONSORED ADS | 44332N106 | BBG000QFPM65 | 3931169 | 78170 | SH |  | SOLE |  | 78170 | 0 | 0 |
| HIGH TEMPLAR TECHNOLOGY LTD | SPON ADS | 747798106 | BBG00HS39BW6 | 583174 | 300605 | SH |  | SOLE |  | 300605 | 0 | 0 |
| HUMANA INC | COM | 444859102 | BBG000BLKK03 | 387527 | 2235 | SH |  | SOLE |  | 2235 | 0 | 0 |
| HOWMET AEROSPACE INC | COM | 443201108 | BBG00DYNJGH9 | 559326 | 2427 | SH |  | DFND |  | 2427 | 0 | 0 |
| IAMGOLD CORP | COM | 450913108 | BBG000LL9LQ5 | 404527 | 21516 | SH |  | SOLE |  | 21516 | 0 | 0 |
| ISHARES GOLD TR | ISHARES NEW | 464285204 | BBG000QLKDR4 | 13220826 | 149964 | SH |  | SOLE |  | 149964 | 0 | 0 |
| INTERNATIONAL BUSINESS MACHS | COM | 459200101 | BBG000BLNNH6 | 7709699 | 31807 | SH |  | DFND |  | 31807 | 0 | 0 |
| IMMUNITYBIO INC | COM | 45256X103 | BBG007T9DYW9 | 538596 | 70221 | SH |  | DFND |  | 70221 | 0 | 0 |
| INTERCONTINENTAL EXCHANGE IN | COM | 45866F104 | BBG000C1FB75 | 316919 | 2015 | SH |  | DFND |  | 2015 | 0 | 0 |
| IDEXX LABS INC | COM | 45168D104 | BBG000BLRT07 | 1890760 | 3365 | SH |  | DFND |  | 3365 | 0 | 0 |
| IDEAYA BIOSCIENCES INC | COM | 45166A102 | BBG00CTZ4D83 | 363088 | 10897 | SH |  | SOLE |  | 10897 | 0 | 0 |
| IMMUNOME INC | COM | 45257U108 | BBG00BR93ZG8 | 429483 | 19638 | SH |  | SOLE |  | 19638 | 0 | 0 |
| IMMUNOVANT INC | COM | 45258J102 | BBG00P5MC0Q8 | 440040 | 17715 | SH |  | DFND |  | 17715 | 0 | 0 |
| INCYTE CORP | COM | 45337C102 | BBG000BNPSQ9 | 944777 | 10038 | SH |  | DFND |  | 10038 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 | BBG000BWM5P3 | 1801336 | 11016 | SH |  | DFND |  | 11016 | 0 | 0 |
| INTEL CORP | COM | 458140100 | BBG000C0G1D1 | 35623236 | 807234 | SH |  | DFND |  | 807234 | 0 | 0 |
| INTUIT | COM | 461202103 | BBG000BH5DV1 | 7107463 | 16438 | SH |  | DFND |  | 16438 | 0 | 0 |
| IONIS PHARMACEUTICALS INC | COM | 462222100 | BBG000JH6683 | 3505802 | 46688 | SH |  | DFND |  | 46688 | 0 | 0 |
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | BBG000FTLBV7 | 191046 | 54429 | SH |  | SOLE |  | 54429 | 0 | 0 |
| IQVIA HLDGS INC | COM | 46266C105 | BBG00333FYS2 | 408614 | 2396 | SH |  | SOLE |  | 2396 | 0 | 0 |
| DISC MEDICINE INC | COM | 254604101 | BBG00W9MJK79 | 433002 | 6772 | SH |  | SOLE |  | 6772 | 0 | 0 |
| IRONWOOD PHARMACEUTICALS INC | COM CL A | 46333X108 | BBG000GBZ3J2 | 95577 | 27230 | SH |  | SOLE |  | 27230 | 0 | 0 |
| INTUITIVE SURGICAL INC | COM NEW | 46120E602 | BBG000BJPDZ1 | 6115032 | 13265 | SH |  | DFND |  | 13265 | 0 | 0 |
| GARTNER INC | COM | 366651107 | BBG000BB65D0 | 316047 | 1996 | SH |  | DFND |  | 1996 | 0 | 0 |
| ILLINOIS TOOL WKS INC | COM | 452308109 | BBG000BMBL90 | 245194 | 942 | SH |  | DFND |  | 942 | 0 | 0 |
| ISHARES TR | CORE S ETF | 464287200 | BBG000BVZ4F5 | 29048902 | 44471 | SH |  | SOLE |  | 44471 | 0 | 0 |
| INVIVYD INC | COM | 00534A102 | BBG00W4ML039 | 50053 | 38502 | SH |  | SOLE |  | 38502 | 0 | 0 |
| JABIL INC | COM | 466313103 | BBG000BJNGN9 | 764749 | 2879 | SH |  | DFND |  | 2879 | 0 | 0 |
| JOHNSON CONTROLS INTERNATION | SHS | G51502105 | BBG000BVWLJ6 | 443135 | 3384 | SH |  | DFND |  | 3384 | 0 | 0 |
| JOHNSON  JOHNSON | COM | 478160104 | BBG000BMHYD1 | 6404083 | 26199 | SH |  | DFND |  | 26199 | 0 | 0 |
| JOYY INC | ADS REPSTG COM A | 46591M109 | BBG003H0XV18 | 6771547 | 115971 | SH |  | DFND |  | 115971 | 0 | 0 |
| JPMORGAN CHASE  CO | COM | 46625H100 | BBG000DMBXR2 | 8231480 | 27983 | SH |  | DFND |  | 27983 | 0 | 0 |
| KEURIG DR PEPPER INC | COM | 49271V100 | BBG000TJM7F0 | 1272977 | 48347 | SH |  | DFND |  | 48347 | 0 | 0 |
| KEYSIGHT TECHNOLOGIES INC | COM | 49338L103 | BBG0059FN811 | 1320362 | 4676 | SH |  | SOLE |  | 4676 | 0 | 0 |
| KINROSS GOLD CORP | COM | 496902404 | BBG000BB2DM7 | 1336666 | 43730 | SH |  | SOLE |  | 43730 | 0 | 0 |
| KRAFT HEINZ CO | COM | 500754106 | BBG005CPNTQ2 | 906347 | 40300 | SH |  | DFND |  | 40300 | 0 | 0 |
| KKR  CO INC | COM | 48251W104 | BBG000BCQ6J8 | 234117 | 2531 | SH |  | DFND |  | 2531 | 0 | 0 |
| KLA CORP | COM NEW | 482480100 | BBG000BMTFR4 | 35002131 | 23772 | SH |  | DFND |  | 23772 | 0 | 0 |
| KINDER MORGAN INC DEL | COM | 49456B101 | BBG0019JZ882 | 234207 | 6985 | SH |  | DFND |  | 6985 | 0 | 0 |
| COCA COLA CO | COM | 191216100 | BBG000BMX289 | 3140409 | 41294 | SH |  | DFND |  | 41294 | 0 | 0 |
| KODIAK SCIENCES INC | COM | 50015M109 | BBG00BVR0D02 | 342661 | 8989 | SH |  | SOLE |  | 8989 | 0 | 0 |
| KRYSTAL BIOTECH INC | COM | 501147102 | BBG00HDGRHH7 | 589228 | 2281 | SH |  | DFND |  | 2281 | 0 | 0 |
| KURA ONCOLOGY INC | COM | 50127T109 | BBG008974342 | 137104 | 16864 | SH |  | SOLE |  | 16864 | 0 | 0 |
| KYMERA THERAPEUTICS INC | COM | 501575104 | BBG00SDHC8D1 | 2184780 | 26231 | SH |  | DFND |  | 26231 | 0 | 0 |
| LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | BBG00TTGH5W4 | 541289 | 29922 | SH |  | SOLE |  | 29922 | 0 | 0 |
| LABCORP HOLDINGS INC | COM SHS | 504922105 | BBG01MMT6PL7 | 383406 | 1437 | SH |  | SOLE |  | 1437 | 0 | 0 |
| L3HARRIS TECHNOLOGIES INC | COM | 502431109 | BBG000BLGFJ9 | 230560 | 668 | SH |  | DFND |  | 668 | 0 | 0 |
| LINDE PLC | SHS | G54950103 | BBG01FND0CC1 | 9705990 | 19578 | SH |  | DFND |  | 19578 | 0 | 0 |
| LUMENTUM HLDGS INC | COM | 55024U109 | BBG0073F9RT7 | 147190271 | 209446 | SH |  | DFND |  | 209446 | 0 | 0 |
| ELI LILLY  CO | COM | 532457108 | BBG000BNBDC2 | 7884268 | 8572 | SH |  | DFND |  | 8572 | 0 | 0 |
| LOCKHEED MARTIN CORP | COM | 539830109 | BBG000C1BW00 | 448458 | 742 | SH |  | DFND |  | 742 | 0 | 0 |
| LOWES COS INC | COM | 548661107 | BBG000BNDN65 | 484610 | 2051 | SH |  | DFND |  | 2051 | 0 | 0 |
| LAM RESEARCH CORP | COM NEW | 512807306 | BBG000BNFLM9 | 24441849 | 114396 | SH |  | DFND |  | 114396 | 0 | 0 |
| LAS VEGAS SANDS CORP | COM | 517834107 | BBG000JWD753 | 313959 | 5827 | SH |  | SOLE |  | 5827 | 0 | 0 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 | BBG00YB1C8M5 | 72800 | 12683 | SH |  | SOLE |  | 12683 | 0 | 0 |
| LYONDELLBASELL INDUSTRIES NV | SHS - A - | N53745100 | BBG000WCFV84 | 5221738 | 64818 | SH |  | DFND |  | 64818 | 0 | 0 |
| MASTERCARD INCORPORATED | CL A | 57636Q104 | BBG000F1ZSQ2 | 4305570 | 8617 | SH |  | DFND |  | 8617 | 0 | 0 |
| MARRIOTT INTL INC NEW | CL A | 571903202 | BBG000BGD7W6 | 5378994 | 16446 | SH |  | DFND |  | 16446 | 0 | 0 |
| MCDONALDS CORP | COM | 580135101 | BBG000BNSZP1 | 2288347 | 7363 | SH |  | DFND |  | 7363 | 0 | 0 |
| MICROCHIP TECHNOLOGY INC. | COM | 595017104 | BBG000BHCP19 | 2079796 | 32190 | SH |  | DFND |  | 32190 | 0 | 0 |
| MCKESSON CORP | COM | 58155Q103 | BBG000DYGNW7 | 679308 | 785 | SH |  | DFND |  | 785 | 0 | 0 |
| MOODYS CORP | COM | 615369105 | BBG000F86GP6 | 238628 | 547 | SH |  | DFND |  | 547 | 0 | 0 |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | BBG000QS6NV8 | 705115 | 1347 | SH |  | DFND |  | 1347 | 0 | 0 |
| MONDELEZ INTL INC | CL A | 609207105 | BBG000D4LWF6 | 2606711 | 45224 | SH |  | DFND |  | 45224 | 0 | 0 |
| MEDTRONIC PLC | SHS | G5960L103 | BBG000BNWG87 | 711396 | 8210 | SH |  | DFND |  | 8210 | 0 | 0 |
| MIMEDX GROUP INC | COM | 602496101 | BBG000RJ6FL5 | 61395 | 15543 | SH |  | SOLE |  | 15543 | 0 | 0 |
| MERCADOLIBRE  INC | COM | 58733R102 | BBG000GQPB11 | 2804471 | 1622 | SH |  | DFND |  | 1622 | 0 | 0 |
| META PLATFORMS INC | CL A | 30303M102 | BBG000MM2P62 | 36267321 | 63390 | SH |  | DFND |  | 63390 | 0 | 0 |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | BBG00MH7T2M7 | 586335 | 6347 | SH |  | DFND |  | 6347 | 0 | 0 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 | BBG00ZXN1GN3 | 321342 | 11862 | SH |  | SOLE |  | 11862 | 0 | 0 |
| 3M CO | COM | 88579Y101 | BBG000BP52R2 | 288136 | 1984 | SH |  | DFND |  | 1984 | 0 | 0 |
| MANNKIND CORP | COM NEW | 56400P706 | BBG000PPL3G9 | 179095 | 73100 | SH |  | SOLE |  | 73100 | 0 | 0 |
| MONSTER BEVERAGE CORP NEW | COM | 61174X109 | BBG008NVB1C0 | 2450887 | 33824 | SH |  | DFND |  | 33824 | 0 | 0 |
| ALTRIA GROUP INC | COM | 02209S103 | BBG000BP6LJ8 | 412965 | 6258 | SH |  | DFND |  | 6258 | 0 | 0 |
| HELLO GROUP INC | ADS | 423403104 | BBG007HTCQT0 | 617708 | 107241 | SH |  | SOLE |  | 107241 | 0 | 0 |
| MARATHON PETE CORP | COM | 56585A102 | BBG001DCCGR8 | 363584 | 1489 | SH |  | DFND |  | 1489 | 0 | 0 |
| MONOLITHIC PWR SYS INC | COM | 609839105 | BBG000C30L48 | 3183835 | 2912 | SH |  | DFND |  | 2912 | 0 | 0 |
| MERCK  CO INC | COM | 58933Y105 | BBG000BPD168 | 3417799 | 28413 | SH |  | DFND |  | 28413 | 0 | 0 |
| MODERNA INC | COM | 60770K107 | BBG003PHHZT1 | 875639 | 17237 | SH |  | DFND |  | 17237 | 0 | 0 |
| MARSH  MCLENNAN COS INC | COM | 571748102 | BBG000BP4MH0 | 313945 | 1810 | SH |  | DFND |  | 1810 | 0 | 0 |
| MARVELL TECHNOLOGY INC | COM | 573874104 | BBG00ZXBJ153 | 21660749 | 218685 | SH |  | DFND |  | 218685 | 0 | 0 |
| MORGAN STANLEY | COM NEW | 617446448 | BBG000BLZRJ2 | 2022565 | 12290 | SH |  | DFND |  | 12290 | 0 | 0 |
| MICROSOFT CORP | COM | 594918104 | BBG000BPH459 | 126759534 | 342436 | SH |  | DFND |  | 342436 | 0 | 0 |
| MOTOROLA SOLUTIONS INC | COM NEW | 620076307 | BBG000BP8Z50 | 1978469 | 4559 | SH |  | DFND |  | 4559 | 0 | 0 |
| STRATEGY INC | CL A NEW | 594972408 | BBG000GQJPZ0 | 1350586 | 10822 | SH |  | DFND |  | 10822 | 0 | 0 |
| METTLER TOLEDO INTERNATIONAL | COM | 592688105 | BBG000BZCKH3 | 413674 | 328 | SH |  | SOLE |  | 328 | 0 | 0 |
| MICRON TECHNOLOGY INC | COM | 595112103 | BBG000C5Z1S3 | 49045247 | 145173 | SH |  | DFND |  | 145173 | 0 | 0 |
| MYRIAD GENETICS INC | COM | 62855J104 | BBG000D9H9F1 | 66191 | 14709 | SH |  | SOLE |  | 14709 | 0 | 0 |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | BBG000GJS7C1 | 591381 | 4489 | SH |  | DFND |  | 4489 | 0 | 0 |
| NORWEGIAN CRUISE LINE HLDGS | SHS | G66721104 | BBG000BSRN78 | 441619 | 23616 | SH |  | DFND |  | 23616 | 0 | 0 |
| NEXTERA ENERGY INC | COM | 65339F101 | BBG000BJSBJ0 | 710904 | 7654 | SH |  | DFND |  | 7654 | 0 | 0 |
| NEWMONT CORP | COM | 651639106 | BBG000BPWXK1 | 4809223 | 44427 | SH |  | DFND |  | 44427 | 0 | 0 |
| NETFLIX INC. | COM | 64110L106 | BBG000CL9VN6 | 17411708 | 181089 | SH |  | DFND |  | 181089 | 0 | 0 |
| NIKE INC | CL B | 654106103 | BBG000C5HS04 | 226651 | 4291 | SH |  | DFND |  | 4291 | 0 | 0 |
| NORTHROP GRUMMAN CORP | COM | 666807102 | BBG000BQ2C28 | 323382 | 474 | SH |  | DFND |  | 474 | 0 | 0 |
| SERVICENOW INC | COM | 81762P102 | BBG000M1R011 | 2999644 | 28691 | SH |  | DFND |  | 28691 | 0 | 0 |
| NURIX THERAPEUTICS INC | COM | 67080M103 | BBG00SDJ8M78 | 291338 | 18796 | SH |  | SOLE |  | 18796 | 0 | 0 |
| NORFOLK SOUTHN CORP | COM | 655844108 | BBG000BQ5DS5 | 240219 | 837 | SH |  | DFND |  | 837 | 0 | 0 |
| NETAPP INC | COM | 64110D104 | BBG000FP1N32 | 552599 | 5397 | SH |  | SOLE |  | 5397 | 0 | 0 |
| INTELLIA THERAPEUTICS INC | COM | 45826J105 | BBG007KC7PB0 | 321910 | 25110 | SH |  | SOLE |  | 25110 | 0 | 0 |
| NATERA INC | COM | 632307104 | BBG001J1BQ86 | 576771 | 2884 | SH |  | SOLE |  | 2884 | 0 | 0 |
| NUVALENT INC | COM | 670703107 | BBG00Z1SLMK5 | 595439 | 5812 | SH |  | DFND |  | 5812 | 0 | 0 |
| NOVAVAX INC | COM NEW | 670002401 | BBG000NVSBL7 | 254180 | 31226 | SH |  | SOLE |  | 31226 | 0 | 0 |
| NVIDIA CORPORATION | COM | 67066G104 | BBG000BBJQV0 | 234702985 | 1345774 | SH |  | DFND |  | 1345774 | 0 | 0 |
| NXP SEMICONDUCTORS N V | COM | N6596X109 | BBG000BND699 | 2942467 | 14947 | SH |  | DFND |  | 14947 | 0 | 0 |
| REALTY INCOME CORP | COM | 756109104 | BBG000DHPN63 | 213886 | 3496 | SH |  | DFND |  | 3496 | 0 | 0 |
| OCUGEN INC | COM | 67577C105 | BBG00194VJB1 | 64367 | 35562 | SH |  | SOLE |  | 35562 | 0 | 0 |
| OLD DOMINION FREIGHT LINE IN | COM | 679580100 | BBG000CHSS88 | 1441271 | 7376 | SH |  | DFND |  | 7376 | 0 | 0 |
| ONEOK INC NEW | COM | 682680103 | BBG000BQHGR6 | 203107 | 2247 | SH |  | DFND |  | 2247 | 0 | 0 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 | BBG00T5JMRT4 | 246507 | 16533 | SH |  | SOLE |  | 16533 | 0 | 0 |
| ON SEMICONDUCTOR CORP | COM | 682189105 | BBG000DV7MX4 | 681429 | 11005 | SH |  | DFND |  | 11005 | 0 | 0 |
| ORACLE CORP | COM | 68389X105 | BBG000BQLTW7 | 8723623 | 59300 | SH |  | DFND |  | 59300 | 0 | 0 |
| ORIC PHARMACEUTICALS INC | COM | 68622P109 | BBG00BL5SLH5 | 183930 | 14517 | SH |  | SOLE |  | 14517 | 0 | 0 |
| ORUKA THERAPEUTICS INC | COM | 687604108 | BBG000BWNN28 | 249664 | 5090 | SH |  | SOLE |  | 5090 | 0 | 0 |
| OREILLY AUTOMOTIVE INC | COM | 67103H107 | BBG000BGYWY6 | 2816286 | 30509 | SH |  | DFND |  | 30509 | 0 | 0 |
| PAN AMERN SILVER CORP | COM | 697900108 | BBG000C0RGY3 | 842449 | 15421 | SH |  | SOLE |  | 15421 | 0 | 0 |
| PALO ALTO NETWORKS INC | COM | 697435105 | BBG0014GJCT9 | 7722454 | 48169 | SH |  | DFND |  | 48169 | 0 | 0 |
| PAYPAY CORP | SPONSORED ADS | 70450C101 | BBG0208Z3BL0 | 342507 | 16050 | SH |  | SOLE |  | 16050 | 0 | 0 |
| PAYCHEX INC | COM | 704326107 | BBG000BQSQ38 | 1153987 | 12527 | SH |  | DFND |  | 12527 | 0 | 0 |
| PACCAR INC | COM | 693718108 | BBG000BQVTF5 | 2163893 | 18735 | SH |  | DFND |  | 18735 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 | BBG009PHHPL8 | 586853 | 10099 | SH |  | DFND |  | 10099 | 0 | 0 |
| PDD HOLDINGS INC | SPONSORED ADS | 722304102 | BBG00LBLDDR2 | 469318155 | 4593053 | SH |  | DFND |  | 4593053 | 0 | 0 |
| PEPSICO INC | COM | 713448108 | BBG000DH7JK6 | 8956195 | 57674 | SH |  | DFND |  | 57674 | 0 | 0 |
| PFIZER INC | COM | 717081103 | BBG000BR2B91 | 928212 | 33056 | SH |  | DFND |  | 33056 | 0 | 0 |
| PROCTER  GAMBLE CO | COM | 742718109 | BBG000BR2TH3 | 3479415 | 24089 | SH |  | DFND |  | 24089 | 0 | 0 |
| PRECIGEN INC | COM | 74017N105 | BBG000QL8VH9 | 155288 | 40126 | SH |  | SOLE |  | 40126 | 0 | 0 |
| PROGRESSIVE CORP | COM | 743315103 | BBG000BR37X2 | 427009 | 2154 | SH |  | DFND |  | 2154 | 0 | 0 |
| PARKER-HANNIFIN CORP | COM | 701094104 | BBG000BR3KL6 | 418077 | 467 | SH |  | DFND |  | 467 | 0 | 0 |
| PROLOGIS INC. | COM | 74340W103 | BBG000B9Z0J8 | 451791 | 3418 | SH |  | DFND |  | 3418 | 0 | 0 |
| PALANTIR TECHNOLOGIES INC | CL A | 69608A108 | BBG000N7QR55 | 22665940 | 154949 | SH |  | DFND |  | 154949 | 0 | 0 |
| PHILIP MORRIS INTL INC | COM | 718172109 | BBG000J2XL74 | 2653872 | 16051 | SH |  | DFND |  | 16051 | 0 | 0 |
| PNC FINL SVCS GROUP INC | COM | 693475105 | BBG000BRD0D8 | 310262 | 1491 | SH |  | DFND |  | 1491 | 0 | 0 |
| INSULET CORP | COM | 45784P101 | BBG000R7XX87 | 327980 | 1563 | SH |  | SOLE |  | 1563 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | BBG00W9LF2G5 | 630204 | 1956 | SH |  | DFND |  | 1956 | 0 | 0 |
| PRIME MEDICINE INC | COM | 74168J101 | BBG011RT3R55 | 94305 | 27099 | SH |  | SOLE |  | 27099 | 0 | 0 |
| PHILLIPS 66 | COM | 718546104 | BBG00286S4N9 | 676798 | 3715 | SH |  | DFND |  | 3715 | 0 | 0 |
| PTC INC | COM | 69370C100 | BBG000C2VBB0 | 463520 | 3253 | SH |  | SOLE |  | 3253 | 0 | 0 |
| PTC THERAPEUTICS INC | COM | 69366J200 | BBG000QT15P7 | 603836 | 8863 | SH |  | DFND |  | 8863 | 0 | 0 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | BBG002B63KM7 | 635878 | 6033 | SH |  | DFND |  | 6033 | 0 | 0 |
| HYPERLIQUID STRATEGIES INC | COM | 44916Y106 | BBG01Y593H53 | 84957 | 16691 | SH |  | SOLE |  | 16691 | 0 | 0 |
| PALVELLA THERAPEUTICS INC NE | COM | 697947109 | BBG0055C3N57 | 228733 | 1835 | SH |  | SOLE |  | 1835 | 0 | 0 |
| QUANTA SVCS INC | COM | 74762E102 | BBG000BBL8V7 | 298118 | 543 | SH |  | DFND |  | 543 | 0 | 0 |
| PAYPAL HLDGS INC | COM | 70450Y103 | BBG0077VNXV6 | 1497022 | 33098 | SH |  | DFND |  | 33098 | 0 | 0 |
| QNITY ELECTRONICS INC | COMMON STOCK | 74743L100 | BBG01TRL73S5 | 658128 | 5704 | SH |  | DFND |  | 5704 | 0 | 0 |
| QUALCOMM INC | COM | 747525103 | BBG000CGC1X8 | 8174954 | 63480 | SH |  | DFND |  | 63480 | 0 | 0 |
| QFIN HOLDINGS INC | AMERICAN DEP | 88557W101 | BBG00MDY4KL0 | 6168592 | 477815 | SH |  | SOLE |  | 477815 | 0 | 0 |
| INVESCO EXCH TRADED FD TR II | NASDAQ 100 ETF | 46138G649 | BBG00XS6PB10 | 1750071 | 7365 | SH |  | SOLE |  | 7365 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 | BBG005SSJYH3 | 185540 | 11348 | SH |  | SOLE |  | 11348 | 0 | 0 |
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | BBG001RWPDW6 | 435676 | 20796 | SH |  | SOLE |  | 20796 | 0 | 0 |
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | BBG000WG3567 | 63549 | 17751 | SH |  | SOLE |  | 17751 | 0 | 0 |
| ROYAL CARIBBEAN GROUP | COM | V7780T103 | BBG000BB5792 | 1722077 | 6258 | SH |  | DFND |  | 6258 | 0 | 0 |
| ARCUS BIOSCIENCES INC | COM | 03969F109 | BBG00DQD26W3 | 312617 | 14473 | SH |  | SOLE |  | 14473 | 0 | 0 |
| REGENERON PHARMACEUTICALS | COM | 75886F107 | BBG000C734W3 | 3727988 | 4825 | SH |  | DFND |  | 4825 | 0 | 0 |
| REPLIMUNE GROUP INC | COM | 76029N106 | BBG00L8Z22R1 | 113931 | 14893 | SH |  | SOLE |  | 14893 | 0 | 0 |
| RALPH LAUREN CORP | CL A | 751212101 | BBG000BS0ZF1 | 737171 | 2143 | SH |  | SOLE |  | 2143 | 0 | 0 |
| RELAY THERAPEUTICS INC | COM | 75943R102 | BBG00DSS08K9 | 188383 | 18933 | SH |  | SOLE |  | 18933 | 0 | 0 |
| RAMBUS INC DEL | COM | 750917106 | BBG000BR32C6 | 997604 | 11596 | SH |  | SOLE |  | 11596 | 0 | 0 |
| RESMED INC | COM | 761152107 | BBG000L4M7F1 | 419104 | 1867 | SH |  | DFND |  | 1867 | 0 | 0 |
| ROIVANT SCIENCES LTD | SHS | G76279101 | BBG007STW2B8 | 530954 | 19168 | SH |  | SOLE |  | 19168 | 0 | 0 |
| ROPER TECHNOLOGIES INC | COM | 776696106 | BBG000F1ZSN5 | 2174116 | 6144 | SH |  | DFND |  | 6144 | 0 | 0 |
| ROSS STORES INC | COM | 778296103 | BBG000BSBZH7 | 2987112 | 13789 | SH |  | DFND |  | 13789 | 0 | 0 |
| RTX CORPORATION | COM | 75513E101 | BBG000BW8S60 | 2669543 | 13839 | SH |  | DFND |  | 13839 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 | BBG00829F4P8 | 567941 | 5840 | SH |  | DFND |  | 5840 | 0 | 0 |
| REVVITY INC | COM | 714046109 | BBG000FXW512 | 340978 | 3892 | SH |  | DFND |  | 3892 | 0 | 0 |
| RECURSION PHARMACEUTICALS IN | CL A | 75629V104 | BBG00PQ4XJ45 | 343687 | 111950 | SH |  | SOLE |  | 111950 | 0 | 0 |
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | BBG007DLZ601 | 561217 | 6453 | SH |  | DFND |  | 6453 | 0 | 0 |
| SANA BIOTECHNOLOGY INC | COM | 799566104 | BBG00N5BMH61 | 128004 | 44446 | SH |  | SOLE |  | 44446 | 0 | 0 |
| SAFE BULKERS INC | COM | Y7388L103 | BBG000FYPPB3 | 510496 | 80647 | SH |  | SOLE |  | 80647 | 0 | 0 |
| SIBANYE STILLWATER LTD | SPONSORED ADR | 82575P107 | BBG00RRGP445 | 319199 | 25909 | SH |  | SOLE |  | 25909 | 0 | 0 |
| STARBUCKS CORP | COM | 855244109 | BBG000CTQBF3 | 3644879 | 40684 | SH |  | DFND |  | 40684 | 0 | 0 |
| SCHWAB CHARLES CORP | COM | 808513105 | BBG000BSLZY7 | 580045 | 6172 | SH |  | DFND |  | 6172 | 0 | 0 |
| ETFS GOLD TR | PHYSCL GOLD SHS | 00326A104 | BBG000BDHB87 | 13693432 | 306890 | SH |  | SOLE |  | 306890 | 0 | 0 |
| SHOPIFY INC | CL A SUB VTG SHS | 82509L107 | BBG008HBD923 | 4634009 | 39066 | SH |  | DFND |  | 39066 | 0 | 0 |
| SHERWIN WILLIAMS CO | COM | 824348106 | BBG000BSXQV7 | 276314 | 862 | SH |  | DFND |  | 862 | 0 | 0 |
| SLB LIMITED | COM STK | 806857108 | BBG000BT41Q8 | 283313 | 5513 | SH |  | DFND |  | 5513 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 | BBG0024L5B86 | 335101 | 10009 | SH |  | SOLE |  | 10009 | 0 | 0 |
| SELLAS LIFE SCIENCES GROUP I | COM NEW | 81642T209 | BBG000VC77H7 | 132627 | 31354 | SH |  | SOLE |  | 31354 | 0 | 0 |
| SUPER MICRO COMPUTER INC | COM NEW | 86800U302 | BBG000MYZDJ3 | 311311 | 13672 | SH |  | SOLE |  | 13672 | 0 | 0 |
| SUMMIT THERAPEUTICS INC | COM | 86627T108 | BBG00X3GQL76 | 5912202 | 311825 | SH |  | DFND |  | 311825 | 0 | 0 |
| SANDISK CORP | COM | 80004C200 | BBG01R388JG1 | 36688979 | 57747 | SH |  | DFND |  | 57747 | 0 | 0 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | BBG000R33JY1 | 366238 | 15678 | SH |  | SOLE |  | 15678 | 0 | 0 |
| SYNOPSYS INC | COM | 871607107 | BBG000BSFRF3 | 4500444 | 11351 | SH |  | DFND |  | 11351 | 0 | 0 |
| SOUTHERN CO | COM | 842587107 | BBG000BT9DW0 | 393705 | 4079 | SH |  | DFND |  | 4079 | 0 | 0 |
| SOHU COM LTD | SPONSORED ADS | 83410S108 | BBG00L2DB535 | 1852996 | 119935 | SH |  | SOLE |  | 119935 | 0 | 0 |
| SOLVENTUM CORP | COM SHS | 83444M101 | BBG018YZH6T3 | 332965 | 5099 | SH |  | SOLE |  | 5099 | 0 | 0 |
| SIMON PPTY GROUP INC NEW | COM | 828806109 | BBG000BJ2D31 | 228872 | 1227 | SH |  | DFND |  | 1227 | 0 | 0 |
| S GLOBAL INC | COM | 78409V104 | BBG000BP1Q11 | 495946 | 1166 | SH |  | DFND |  | 1166 | 0 | 0 |
| ARS PHARMACEUTICALS INC | COM | 82835W108 | BBG00FZQGXG3 | 118740 | 14787 | SH |  | SOLE |  | 14787 | 0 | 0 |
| STATE STR SPDR S 500 ETF T | TR UNIT | 78462F103 | BBG000BDTBL9 | 10943271 | 16827 | SH |  | SOLE |  | 16827 | 0 | 0 |
| SEMPRA | COM | 816851109 | BBG000C2ZCH8 | 226309 | 2329 | SH |  | DFND |  | 2329 | 0 | 0 |
| SAREPTA THERAPEUTICS INC | COM | 803607100 | BBG000BCJ161 | 445057 | 20453 | SH |  | SOLE |  | 20453 | 0 | 0 |
| SCHOLAR ROCK HLDG CORP | COM | 80706P103 | BBG00KT2RRM6 | 661153 | 13449 | SH |  | DFND |  | 13449 | 0 | 0 |
| STERIS PLC | SHS USD | G8473T100 | BBG00MRHG523 | 389852 | 1763 | SH |  | SOLE |  | 1763 | 0 | 0 |
| SCORPIO TANKERS INC | SHS | Y7542C130 | BBG000Q1TVZ0 | 260713 | 3492 | SH |  | SOLE |  | 3492 | 0 | 0 |
| STOKE THERAPEUTICS INC | COM | 86150R107 | BBG00JPCBPG9 | 245177 | 7530 | SH |  | SOLE |  | 7530 | 0 | 0 |
| SEAGATE TECHNOLOGY HLDNGS PL | ORD SHS | G7997R103 | BBG0113JGQF0 | 5058405 | 12912 | SH |  | DFND |  | 12912 | 0 | 0 |
| SAVARA INC | COM | 805111101 | BBG000MS0823 | 129686 | 23752 | SH |  | SOLE |  | 23752 | 0 | 0 |
| SKYWORKS SOLUTIONS INC | COM | 83088M102 | BBG000KLB4Q1 | 210130 | 3924 | SH |  | DFND |  | 3924 | 0 | 0 |
| STRYKER CORPORATION | COM | 863667101 | BBG000DN7P92 | 717969 | 2185 | SH |  | DFND |  | 2185 | 0 | 0 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | BBG0067L94B2 | 360949 | 7156 | SH |  | SOLE |  | 7156 | 0 | 0 |
| AT INC | COM | 00206R102 | BBG000BSJK37 | 759103 | 26185 | SH |  | DFND |  | 26185 | 0 | 0 |
| TAL ED GROUP | SPONSORED ADS | 874080104 | BBG0016XJ8S0 | 24337712 | 2140520 | SH |  | DFND |  | 2140520 | 0 | 0 |
| TRANSDIGM GROUP INC | COM | 893641100 | BBG000L8CBX4 | 246858 | 213 | SH |  | DFND |  | 213 | 0 | 0 |
| TELEDYNE TECHNOLOGIES INC | COM | 879360105 | BBG000BMT9T6 | 771388 | 1275 | SH |  | SOLE |  | 1275 | 0 | 0 |
| ATLASSIAN CORPORATION | CL A | 049468101 | BBG01BGWHFR5 | 367049 | 5378 | SH |  | DFND |  | 5378 | 0 | 0 |
| BIO-TECHNE CORP | COM | 09073M104 | BBG000C15114 | 336188 | 6433 | SH |  | DFND |  | 6433 | 0 | 0 |
| TE CONNECTIVITY PLC | ORD SHS | G87052109 | BBG01Q08MMR1 | 1677594 | 8026 | SH |  | DFND |  | 8026 | 0 | 0 |
| TERADYNE INC | COM | 880770102 | BBG000BV4DR6 | 1276557 | 4306 | SH |  | DFND |  | 4306 | 0 | 0 |
| TRUIST FINL CORP | COM | 89832Q109 | BBG000BYYLS8 | 216381 | 4707 | SH |  | DFND |  | 4707 | 0 | 0 |
| TARGET CORP | COM | 87612E106 | BBG000H8TVT2 | 203495 | 1679 | SH |  | DFND |  | 1679 | 0 | 0 |
| TG THERAPEUTICS INC | COM | 88322Q108 | BBG000FVZQY1 | 687853 | 20706 | SH |  | DFND |  | 20706 | 0 | 0 |
| TJX COS INC NEW | COM | 872540109 | BBG000BV8DN6 | 1081968 | 6775 | SH |  | DFND |  | 6775 | 0 | 0 |
| TENCENT MUSIC ENTMT GROUP | SPON ADS | 88034P109 | BBG00LDC5RK5 | 26071723 | 2809453 | SH |  | DFND |  | 2809453 | 0 | 0 |
| THERMO FISHER SCIENTIFIC INC | COM | 883556102 | BBG000BVDLH9 | 993382 | 2021 | SH |  | DFND |  | 2021 | 0 | 0 |
| T-MOBILE US INC | COM | 872590104 | BBG000NDV1D4 | 7740445 | 36854 | SH |  | DFND |  | 36854 | 0 | 0 |
| TANGO THERAPEUTICS INC | COM | 87583X109 | BBG00WFDDRS0 | 276018 | 13194 | SH |  | SOLE |  | 13194 | 0 | 0 |
| TOLL BROTHERS INC | COM | 889478103 | BBG000BVHBM1 | 649324 | 4758 | SH |  | SOLE |  | 4758 | 0 | 0 |
| TAPESTRY INC | COM | 876030107 | BBG000BY29C7 | 1823283 | 12921 | SH |  | DFND |  | 12921 | 0 | 0 |
| THOMSON REUTERS CORP | COM | 884903808 | BBG000BBS9F6 | 1277266 | 14195 | SH |  | DFND |  | 14195 | 0 | 0 |
| TRIMBLE INC | COM | 896239100 | BBG000BNPS52 | 412775 | 6328 | SH |  | SOLE |  | 6328 | 0 | 0 |
| TRAVELERS COMPANIES INC | COM | 89417E109 | BBG000BJ81C1 | 243261 | 834 | SH |  | DFND |  | 834 | 0 | 0 |
| TOWER SEMICONDUCTOR LTD | SHS NEW | M87915274 | BBG000BH91G0 | 61023521 | 347752 | SH |  | DFND |  | 347752 | 0 | 0 |
| TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | BBG00TJXFDP1 | 168515 | 37699 | SH |  | SOLE |  | 37699 | 0 | 0 |
| TESLA INC | COM | 88160R101 | BBG000N9MNX3 | 35413649 | 95262 | SH |  | DFND |  | 95262 | 0 | 0 |
| TAIWAN SEMICONDUCTOR MANUFAC | SPONSORED ADS | 874039100 | BBG000BD8ZK0 | 176096621 | 521073 | SH |  | DFND |  | 521073 | 0 | 0 |
| TRANE TECHNOLOGIES PLC | SHS | G8994E103 | BBG000BM6788 | 337560 | 810 | SH |  | DFND |  | 810 | 0 | 0 |
| TAKE-TWO INTERACTIVE SOFTWAR | COM | 874054109 | BBG000BS1YV5 | 1295205 | 6558 | SH |  | DFND |  | 6558 | 0 | 0 |
| TRAVERE THERAPEUTICS INC | COM | 89422G107 | BBG000P9D6W9 | 569303 | 19162 | SH |  | SOLE |  | 19162 | 0 | 0 |
| TWIST BIOSCIENCE CORP | COM | 90184D100 | BBG006KDCHJ4 | 574992 | 12100 | SH |  | SOLE |  | 12100 | 0 | 0 |
| TEXAS INSTRS INC | COM | 882508104 | BBG000BVV7G1 | 16059455 | 82721 | SH |  | DFND |  | 82721 | 0 | 0 |
| TYLER TECHNOLOGIES INC | COM | 902252105 | BBG000BVWZF9 | 406063 | 1186 | SH |  | DFND |  | 1186 | 0 | 0 |
| UBER TECHNOLOGIES INC | COM | 90353T100 | BBG002B04MT8 | 551847 | 7672 | SH |  | DFND |  | 7672 | 0 | 0 |
| UNIVERSAL HLTH SVCS INC | CL B | 913903100 | BBG000CB8Q50 | 330737 | 1848 | SH |  | SOLE |  | 1848 | 0 | 0 |
| UNITEDHEALTH GROUP INC | COM | 91324P102 | BBG000CH5208 | 2820089 | 10422 | SH |  | DFND |  | 10422 | 0 | 0 |
| UNION PAC CORP | COM | 907818108 | BBG000BW3299 | 530853 | 2188 | SH |  | DFND |  | 2188 | 0 | 0 |
| UNITED PARCEL SVCS INC | CL B | 911312106 | BBG000L9CV04 | 264643 | 2690 | SH |  | DFND |  | 2690 | 0 | 0 |
| US BANCORP | COM NEW | 902973304 | BBG000FFDM15 | 294637 | 5665 | SH |  | DFND |  | 5665 | 0 | 0 |
| UNITED STS OIL FD LP | UNITS | 91232N207 | BBG000NL49J3 | 14819408 | 116459 | SH |  | SOLE |  | 116459 | 0 | 0 |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | BBG000BV4XJ1 | 635081 | 1071 | SH |  | DFND |  | 1071 | 0 | 0 |
| VISA INC | COM CL A | 92826C839 | BBG000PSKYX7 | 5249002 | 17367 | SH |  | DFND |  | 17367 | 0 | 0 |
| VERICEL CORP | COM | 92346J108 | BBG000BDCM24 | 240181 | 7466 | SH |  | SOLE |  | 7466 | 0 | 0 |
| VERACYTE INC | COM | 92337F107 | BBG001J2M542 | 421951 | 13100 | SH |  | SOLE |  | 13100 | 0 | 0 |
| VERA THERAPEUTICS INC | CL A | 92337R101 | BBG00Q72WYG3 | 514743 | 12795 | SH |  | SOLE |  | 12795 | 0 | 0 |
| VIPSHOP HLDGS LTD | SPONSORED ADS A | 92763W103 | BBG002NLDLV8 | 21130399 | 1344173 | SH |  | DFND |  | 1344173 | 0 | 0 |
| VIR BIOTECHNOLOGY INC | COM | 92764N102 | BBG00H2QQ8T5 | 151388 | 16896 | SH |  | SOLE |  | 16896 | 0 | 0 |
| VIKING THERAPEUTICS INC | COM | 92686J106 | BBG006LGV869 | 515954 | 15856 | SH |  | SOLE |  | 15856 | 0 | 0 |
| VALERO ENERGY CORP | COM | 91913Y100 | BBG000BBGGQ1 | 606087 | 2453 | SH |  | DFND |  | 2453 | 0 | 0 |
| VANDA PHARMACEUTICALS INC | COM | 921659108 | BBG000HT5MG6 | 80177 | 11603 | SH |  | SOLE |  | 11603 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | BBG002H242Z5 | 349087 | 17847 | SH |  | SOLE |  | 17847 | 0 | 0 |
| VERISK ANALYTICS INC | COM | 92345Y106 | BBG000BCZL41 | 928067 | 4891 | SH |  | DFND |  | 4891 | 0 | 0 |
| VERISIGN INC | COM | 92343E102 | BBG000BGKHZ3 | 566012 | 2279 | SH |  | SOLE |  | 2279 | 0 | 0 |
| VERTIV HOLDINGS CO | COM CL A | 92537N108 | BBG00L2B8KW8 | 2768408 | 11048 | SH |  | DFND |  | 11048 | 0 | 0 |
| VERTEX PHARMACEUTICALS INC | COM | 92532F100 | BBG000C1S2X2 | 4829777 | 10816 | SH |  | DFND |  | 10816 | 0 | 0 |
| VERASTEM INC | COM NEW | 92337C203 | BBG001J2LSK5 | 72700 | 13717 | SH |  | SOLE |  | 13717 | 0 | 0 |
| VIATRIS INC | COM | 92556V106 | BBG00Y4RQNH4 | 372133 | 27545 | SH |  | DFND |  | 27545 | 0 | 0 |
| VERIZON COMMUNICATIONS INC | COM | 92343V104 | BBG000HS77T5 | 2183650 | 43499 | SH |  | DFND |  | 43499 | 0 | 0 |
| WATERS CORP | COM | 941848103 | BBG000FQRVM3 | 418111 | 1404 | SH |  | SOLE |  | 1404 | 0 | 0 |
| WEIBO CORP | SPONSORED ADR | 948596101 | BBG0065XPGX9 | 3042532 | 347718 | SH |  | SOLE |  | 347718 | 0 | 0 |
| WARNER BROS DISCOVERY INC | COM SER A | 934423104 | BBG011386VF4 | 2412004 | 87837 | SH |  | DFND |  | 87837 | 0 | 0 |
| WORKDAY INC | CL A | 98138H101 | BBG000VC0T95 | 1657260 | 12756 | SH |  | DFND |  | 12756 | 0 | 0 |
| WESTERN DIGITAL CORP | COM | 958102105 | BBG000BWNFZ9 | 5563979 | 20570 | SH |  | DFND |  | 20570 | 0 | 0 |
| WELLTOWER INC | COM | 95040Q104 | BBG000BKY1G5 | 508510 | 2572 | SH |  | DFND |  | 2572 | 0 | 0 |
| WELLS FARGO  CO | COM | 949746101 | BBG000BWQFY7 | 2568617 | 32265 | SH |  | DFND |  | 32265 | 0 | 0 |
| WASTE MGMT INC DEL | COM | 94106L109 | BBG000BWVSR1 | 301254 | 1311 | SH |  | DFND |  | 1311 | 0 | 0 |
| WILLIAMS COS INC | COM | 969457100 | BBG000BWVCP8 | 320596 | 4405 | SH |  | DFND |  | 4405 | 0 | 0 |
| WALMART INC | COM | 931142103 | BBG000BWXBC2 | 25014830 | 201278 | SH |  | DFND |  | 201278 | 0 | 0 |
| WILLIAMS SONOMA INC | COM | 969904101 | BBG000FSMWC3 | 1008102 | 5529 | SH |  | DFND |  | 5529 | 0 | 0 |
| WEST PHARMACEUTICAL SVSC INC | COM | 955306105 | BBG000BX24N8 | 389996 | 1556 | SH |  | SOLE |  | 1556 | 0 | 0 |
| SPDR SERIES TRUST | STATE STREET SPD | 78464A870 | BBG000MQQ963 | 16413305 | 128500 | SH |  | SOLE |  | 128500 | 0 | 0 |
| XCEL ENERGY INC | COM | 98389B100 | BBG000BCTQ65 | 1775881 | 22355 | SH |  | DFND |  | 22355 | 0 | 0 |
| EXXON MOBIL CORP | COM | 30231G102 | BBG000GZQ728 | 9936817 | 58569 | SH |  | DFND |  | 58569 | 0 | 0 |
| FULL TRUCK ALLIANCE CO LTD | SPONSORED ADS | 35969L108 | BBG01186DLS3 | 37424160 | 4508935 | SH |  | SOLE |  | 4508935 | 0 | 0 |
| YUM CHINA HLDGS INC | COM | 98850P109 | BBG00B8N0HG1 | 6818411 | 138700 | SH |  | SOLE |  | 138700 | 0 | 0 |
| ZIMMER BIOMET HOLDINGS INC | COM | 98956P102 | BBG000BKPL53 | 366111 | 4049 | SH |  | SOLE |  | 4049 | 0 | 0 |
| ZEBRA TECHNOLOGIES CORPORATI | CL A | 989207105 | BBG000CC7LQ7 | 284558 | 1361 | SH |  | DFND |  | 1361 | 0 | 0 |
| ZHIHU INC | SPONSORED ADS | 98955N207 | BBG00ZKGL1K6 | 1887666 | 664671 | SH |  | SOLE |  | 664671 | 0 | 0 |
| ZSCALER INC | COM | 98980G102 | BBG003338H34 | 719968 | 5132 | SH |  | DFND |  | 5132 | 0 | 0 |
| ZOETIS INC | CL A | 98978V103 | BBG0039320N9 | 495064 | 4188 | SH |  | DFND |  | 4188 | 0 | 0 |

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