# EDGAR Filing Document

**Accession Number:** 0002123613
**File Stem:** 0001193125-26-274688
**Filing Date:** 2026-6
**Character Count:** 15028
**Document Hash:** baaa7857b14cd50272e1b3f73f8166eb
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-274688.hdr.sgml**: 20260617

**ACCESSION NUMBER**: 0001193125-26-274688

**CONFORMED SUBMISSION TYPE**: S-1MEF

**PUBLIC DOCUMENT COUNT**: 14

**FILED AS OF DATE**: 20260617

**DATE AS OF CHANGE**: 20260617

**EFFECTIVENESS DATE**: 20260617

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Kardigan, Inc.
- **CENTRAL INDEX KEY:** 0002123613
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 932994203
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-1MEF
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-296870
- **FILM NUMBER:** 261100195

**BUSINESS ADDRESS:**
- **STREET 1:** C/O KARDIGAN, INC.
- **STREET 2:** 131 OYSTER POINT BLVD., SECOND FLOOR
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080
- **BUSINESS PHONE:** (415) 573-3220

**MAIL ADDRESS:**
- **STREET 1:** C/O KARDIGAN, INC.
- **STREET 2:** 131 OYSTER POINT BLVD., SECOND FLOOR
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080

**As filed with the Securities and Exchange Commission on June 17, 2026.** 

**Registration No. 333–296236** 

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**Washington, D.C. 20549** 

**FORM S-1** 

**REGISTRATION STATEMENT** 

***UNDER***

***THE SECURITIES ACT OF 1933***

## Kardigan, Inc.
**(Exact name of registrant as specified in its charter)** 

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| | | |
|:---|:---|:---|
| **Delaware** | **2834** | **99-2994203** |
| **(State or other jurisdiction of**<br> **incorporation or organization)** | **(Primary Standard Industrial**<br> **Classification Code Number)** | **(I.R.S. Employer**<br> **Identification No.)** |

---

**Kardigan, Inc.** 

**506 Carnegie Center Drive, Suite 201** 

**Princeton, NJ 08540** 

**(415) 573-3220** 

**(Address, including zip code, and telephone number, including area code, of registrant's principal executive offices)** 

**Tassos Gianakakos** 

**Chief Executive Officer** 

**Kardigan, Inc.** 

**506 Carnegie Center Drive, Suite 201** 

**Princeton, NJ 08540** 

**(415) 573-3220** 

**(Name, address, including zip code, and telephone number, including area code, of agent for service)** 

***Copies to:***

---

| | |
|:---|:---|
| **Mitchell S. Bloom**<br> **Benjamin K. Marsh**<br> **Janet Hsueh**<br> **Goodwin Procter LLP**<br> **100 Northern Avenue**<br> **Boston, MA 02210**<br> **(617) 570-1000** | **Peter N. Handrinos**<br> **Elisabeth M. Martin**<br> **Latham & Watkins LLP**<br> **200 Clarendon Street**<br> **Boston, MA 02116**<br> **(617) 880-4500** |

---

**Approximate date of commencement of proposed sale to the public**: As soon as practicable after the effective date of this registration statement.

If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933 check the following box: ☐

If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☒ (333-296236)

If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐

If this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act.

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| | | | |
|:---|:---|:---|:---|
| Large accelerated filer | ☐ | Accelerated filer | ☐ |
| Non-accelerated filer | ☒ | Smaller reporting company | ☒ |
|  |  | Emerging growth company | ☒ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

**The Registration Statement shall become effective upon filing in accordance with Rule 462(b) promulgated under the Securities Act of 1933, as amended.** 

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**EXPLANATORY NOTE AND INCORPORATION BY REFERENCE** 

This Registration Statement is being filed pursuant to Rule 462(b) under the Securities Act of 1933, as amended (the "Securities Act"), for the sole purpose of increasing the aggregate number of shares of common stock offered by Kardigan, Inc. (the "Registrant") by 1,916,666 shares, 250,000 of which are subject to purchase upon exercise of the underwriters' option to purchase additional shares of the Registrant's common stock. The contents of the Registration Statement on Form S-1, as amended ([File No. 333-296236](http://www.sec.gov/Archives/edgar/data/2123613/000119312526266629/d107928ds1a.htm)), filed by the Registrant with the Securities and Exchange Commission (the "Commission") pursuant to the Securities Act, including all amendments and exhibits thereto (the "Prior Registration Statement"), which was declared effective by the Commission on June 17, 2026, are incorporated by reference into this Registration Statement.

The additional shares of common stock that are being registered for issuance and sale are in an amount and at a price that together represent no more than 20% of the maximum aggregate offering price set forth in Exhibit 107 of the Prior Registration Statement.

The required opinion and consents are listed on an Exhibit Index attached hereto and filed herewith or incorporated by reference herein.

**EXHIBIT INDEX** 

---

| | |
|:---|:---|
| **Exhibit**<br> **No.** | **Exhibit Index** |
| 5.1 | [Opinion of Goodwin Procter LLP](d132513dex51.htm) |
| 23.1 | [Consent of PricewaterhouseCoopers LLP, Independent Registered Public Accounting Firm](d132513dex231.htm) |
| 23.2 | [Consent of Goodwin Procter LLP (included in Exhibit 5.1)](d132513dex51.htm) |
| 24.1\* | [Power of Attorney](http://www.sec.gov/Archives/edgar/data/2123613/000119312526239298/d107928ds1.htm#sig) |
| 107 | [Filing Fee Table](d132513dexfilingfees.htm) |

---

\* Previously included on the signature page to the Prior Registration Statement, originally filed with the Securities and Exchange Commission on May 26, 2026 and incorporated by reference herein.

------

**SIGNATURES** 

Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the Municipality of Princeton, New Jersey, on the 17 day of June, 2026.

---

| | |
|:---|:---|
| **Kardigan, Inc.** | **Kardigan, Inc.** |
| By: | /s/ Tassos Gianakakos |
|  | Tassos Gianakakos |
|  | Chief Executive Officer, Director, and Chair |

---

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons in their capacities and on the date indicated.

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| | |
|:---|:---|
| **Signature** | **Title** |
| /s/ Tassos Gianakakos<br> Tassos Gianakakos | Chief Executive Officer, Director, and Chair<br> (*Principal Executive Officer*) |
| /s/ Brianne Puglisi<br> Brianne Puglisi | Chief Financial Officer<br> (*Principal Financial Officer and Principal Accounting Officer*) |
| \*<br> Paul Berns | Director |
| \*<br> David Meeker, M.D. | Director |
| \*<br> Douglas Giordano | Director |
| \*<br> Kim Popovits | Director |
| \*<br> Tim Walbert | Director |

---

---

| | |
|:---|:---|
| \*By: | /s/ Tassos Gianakakos |
|  | Tassos Gianakakos |
|  | Attorney-in-Fact |

---

## Exhibit 5.1

**Exhibit 5.1** 

---

| | |
|:---|:---|
| ![LOGO](g132513g05n50.jpg) | Goodwin Procter LLP<br> 100 Northern Avenue<br> Boston. MA 02210<br>goodwinlaw.com<br> +1 617 570 1000 |

---

June 17, 2026

Kardigan, Inc.

506 Carnegie Center Drive, Suite 201

Princeton, NJ 08540

Re: <u>Securities Registered under Registration Statement on Form S-1</u>

We have acted as counsel to you in connection with your filing of (i) a Registration Statement on Form S-1 (File No. 333-296236) (as amended or supplemented, the "Initial Registration Statement") pursuant to the Securities Act of 1933, as amended (the "Securities Act"), and (ii) a second Registration Statement on Form S-1 filed pursuant to Rule 462(b) promulgated under the Securities Act (the "462(b) Registration Statement," and together with the Initial Registration Statement, the "Registration Statement"). This opinion letter is being furnished to you in connection with your filing of the 462(b) Registration Statement relating to the registration of the offering by Kardigan, Inc., a Delaware corporation (the "Company"), of up to 1,916,666 shares (the "Shares") of the Company's voting Common Stock, $0.00001 par value per share, including Shares purchasable by the underwriters upon their exercise of an over-allotment option granted to the underwriters by the Company. The Shares are being sold to the several underwriters named in, and pursuant to, an underwriting agreement among the Company and such underwriters (the "Underwriting Agreement").

We have reviewed such documents and made such examination of law as we have deemed appropriate to give the opinion set forth below. We have relied, without independent verification, on certificates of public officials and, as to matters of fact material to the opinion set forth below, on certificates of officers of the Company.

The opinion set forth below is limited to the Delaware General Corporation Law.

Based on the foregoing, we are of the opinion that the Shares have been duly authorized and, when delivered and paid for in accordance with the terms of the Underwriting Agreement, will be validly issued, fully paid and non-assessable.

This opinion letter and the opinion it contains shall be interpreted in accordance with the Core Opinion Principles as published in 74 *Business Lawyer* 815 (Summer 2019).

We hereby consent to the inclusion of this opinion as Exhibit 5.1 to the Registration Statement and to the references to our firm under the caption "Legal Matters" in the Registration Statement. In giving our consent, we do not admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations thereunder.

------

Kardigan, Inc.

June 17, 2026

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| |
|:---|
| Very truly yours, |
| /s/ Goodwin Procter LLP |
| GOODWIN PROCTER LL |

---

## Exhibit 23.1

**Exhibit 23.1** 

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in this Registration Statement on Form S-1 of Kardigan, Inc. of our report dated March 26, 2026, except for the effects of the stock split discussed in Note 2 to the consolidated financial statements, as to which the date is June 11, 2026, relating to the financial statements, which appears in Amendment No. 1 to the Registration Statement on Form S-1 (No. 333-296236) of Kardigan, Inc. We also consent to the reference to us under the heading "Experts" in Amendment No. 1 to the Registration Statement on Form S-1 (No. 333-296236) incorporated by reference in this Registration Statement.

/s/ PricewaterhouseCoopers LLP

San Jose, California

June 17, 2026

## Ex-Filing

?xml version='1.0' encoding='ASCII'? EX-FILING FEES

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| |
|:---|
| **Calculation of Filing Fee Tables**  |
| &nbsp;&nbsp;&nbsp;&nbsp;**S-1**  |
| &nbsp;&nbsp;&nbsp;&nbsp;**Kardigan, Inc.**  |

---

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| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | | **Security Type**  | **Security Class Title**  | **Fee Calculation or Carry Forward Rule**  | **Amount Registered**  | **Proposed Maximum Offering Price Per Unit**  | **Maximum Aggregate Offering Price**  | **Fee Rate**  | **Amount of Registration Fee**  |
| **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** | **Newly Registered Securities** |
| Fees to be Paid | 1 | Equity | Common Stock, $0.00001 par value per share | 457(a) | 1916666 | $16.00 | $30666656.00 | 0.0001381 | $4235.07 |
| Fees Previously Paid |  |  |  |  |  |  |  |  |  |
| **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** | **Carry Forward Securities** |
| Carry Forward Securities |  |  |  |  |  |  |  |  |  |
|  |  |  | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: |  | $30666656.00  |  | $4235.07  |
|  |  |  | Total Fees Previously Paid:  | Total Fees Previously Paid:  | Total Fees Previously Paid:  |  |  |  | $0.00  |
|  |  |  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  |  |  |  | $0.00  |
|  |  |  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  |  |  |  | $4235.07  |

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 **Offering Note** <br>

<sup>1</sup> (1) Represents only the additional number of shares being registered and includes 250,000 shares of common stock that the underwriters have the option to purchase. Does not include the securities that the Registrant previously registered on the Registration Statement on Form S-1 (File No. 333-296236), as amended (the "Prior Registration Statement"). (2) Estimated solely for the purpose of computing the registration fee in accordance with Rule 457(a) under the Securities Act of 1933, as amended (the "Securities Act"). (3) The registrant previously registered securities at an aggregate offering price not to exceed $429,333,344.00, which was declared effective by the Securities and Exchange Commission on June 17, 2026. In accordance with Rule 462(b) under the Securities Act, an additional amount of securities having a proposed maximum aggregate offering price of $16 per share is hereby registered, which includes shares issuable upon the exercise of the underwriters' option to purchase additional shares.

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| |
|:---|
| |
| **Rules 457(b) and 0-11(a)(2)** |
| Fee Offset Claims |
| Fee Offset Sources |
| **Rule 457(p)** |
| Fee Offset Claims |
| Fee Offset Sources |

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