# EDGAR Filing Document

**Accession Number:** 0001339970
**File Stem:** 0001339970-25-000018
**Filing Date:** 2025-8
**Character Count:** 2677
**Document Hash:** 0ac587097db51ff0f12c072bec49f989
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001339970-25-000018.hdr.sgml**: 20250917

**ACCESSION NUMBER**: 0001339970-25-000018

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250813

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** aTYR PHARMA INC
- **CENTRAL INDEX KEY:** 0001339970
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 203435077
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 10240 SORRENTO VALLEY ROAD
- **STREET 2:** SUITE 300
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121
- **BUSINESS PHONE:** 8587318389

**MAIL ADDRESS:**
- **STREET 1:** 10240 SORRENTO VALLEY ROAD
- **STREET 2:** SUITE 300
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121

**aTyr Pharma, Inc.**<br> 10240 Sorrento Valley Road, Suite 300<br>San Diego, California 92121

August 14, 2025

<br>Securities and Exchange Commission<br>Division of Corporation Finance<br>Office of Life Sciences<br>100 F. Street N.E.<br>Washington, D.C. 20549-3010

Attention: Tyler Howes

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| | |
|:---|:---|
| **Re:** | **aTyr Pharma, Inc.** |
|  | **Registration Statement on Form S-3** |
|  | **Filed: August 7, 2025** |
|  | **File No. 333-289360** |

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Ladies and Gentlemen:

aTyr Pharma, Inc. (the "***Registrant***") hereby requests that the U.S. Securities and Exchange Commission (the "***Commission***") take appropriate action to cause the above-referenced Registration Statement on Form S-3 to become effective on August 18, 2025, at 4:00 p.m., Eastern Time, or as soon thereafter as is practicable or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes Charles Bair and Nicholaus Johnson of Cooley LLP, counsel to the Registrant, to make such request on its behalf.

Once the Registration Statement has been declared effective, please orally confirm that event with Charles Bair of Cooley LLP at (858) 550-6142 or, in his absence, Nicholaus Johnson of Cooley LLP at (858) 550-6198.

[*Signature Page Follows*]

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Very truly yours,

**ATYR PHARMA, INC.**

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| | |
|:---|:---|
| By: | <u>/s/ Jill M. Broadfoot</u> |
| Name: | Jill Broadfoot |
| Title: | Chief Financial Officer |

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| | |
|:---|:---|
| cc: | Charles Bair, *Cooley LLP* |
|  | Nicholaus Johnson, *Cooley LLP* |
|  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Nancy Denyes, *aTyr Pharma, Inc.* |

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[Company Signature Page to Acceleration Request]

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