# EDGAR Filing Document

**Accession Number:** 0001576263
**File Stem:** 0000902664-23-001727
**Filing Date:** 2023-2
**Character Count:** 18040
**Document Hash:** a3a2dca11f70d2a8384d6c9087296323
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000902664-23-001727.hdr.sgml**: 20230214

**ACCESSION NUMBER**: 0000902664-23-001727

**CONFORMED SUBMISSION TYPE**: SC 13G

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230214

**DATE AS OF CHANGE**: 20230214

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Mirati Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001576263
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 462693615
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-87670
- **FILM NUMBER:** 23623867

**BUSINESS ADDRESS:**
- **STREET 1:** 3545 CRAY COURT
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121
- **BUSINESS PHONE:** 858-332-3410

**MAIL ADDRESS:**
- **STREET 1:** 3545 CRAY COURT
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** RTW INVESTMENTS, LP
- **CENTRAL INDEX KEY:** 0001493215
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G

**BUSINESS ADDRESS:**
- **STREET 1:** 40 10TH AVENUE
- **STREET 2:** 7TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10014
- **BUSINESS PHONE:** 646-597-6980

**MAIL ADDRESS:**
- **STREET 1:** 40 10TH AVENUE
- **STREET 2:** 7TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10014

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** RTW INVESTMENTS, LLC
- **DATE OF NAME CHANGE:** 20100602

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| | |
|:---|:---|
| &nbsp;&nbsp;**SECURITIES AND EXCHANGE COMMISSION** | &nbsp;&nbsp;**SECURITIES AND EXCHANGE COMMISSION** |
| &nbsp;&nbsp;**Washington, D.C. 20549** | &nbsp;&nbsp;**Washington, D.C. 20549** |
| &nbsp;&nbsp;**SCHEDULE 13G** | &nbsp;&nbsp;**SCHEDULE 13G** |
| &nbsp;&nbsp;Under the Securities Exchange Act of 1934 | &nbsp;&nbsp;Under the Securities Exchange Act of 1934 |
| &nbsp;&nbsp;(Amendment No.)\* | &nbsp;&nbsp;(Amendment No.)\* |
| &nbsp;&nbsp; Mirati Therapeutics, Inc. | &nbsp;&nbsp; Mirati Therapeutics, Inc. |
| &nbsp;&nbsp;(Name of Issuer) | &nbsp;&nbsp;(Name of Issuer) |
| &nbsp;&nbsp; Common Stock, par value $0.001 per share | &nbsp;&nbsp; Common Stock, par value $0.001 per share |
| &nbsp;&nbsp;(Title of Class of Securities) | &nbsp;&nbsp;(Title of Class of Securities) |
| &nbsp;&nbsp; 60468T105 | &nbsp;&nbsp; 60468T105 |
| &nbsp;&nbsp;(CUSIP Number) | &nbsp;&nbsp;(CUSIP Number) |
| &nbsp;&nbsp; December 31, 2022 | &nbsp;&nbsp; December 31, 2022 |
| &nbsp;&nbsp;(Date of event which requires filing of this statement) | &nbsp;&nbsp;(Date of event which requires filing of this statement) |
| &nbsp;&nbsp;Check the appropriate box to designate the rule pursuant to which this Schedule 13G is filed: | &nbsp;&nbsp;Check the appropriate box to designate the rule pursuant to which this Schedule 13G is filed: |
| &nbsp;&nbsp;⌧ | &nbsp;&nbsp;Rule 13d-1(b) |
| &nbsp;&nbsp;◻ | &nbsp;&nbsp;Rule 13d-1(c) |
| &nbsp;&nbsp;◻ | &nbsp;&nbsp;Rule 13d-1(d) |
| &nbsp;&nbsp;(Page 1 of 8 Pages) | &nbsp;&nbsp;(Page 1 of 8 Pages) |

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______________________________

\* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 (the "Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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| | | |
|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 2 of 8 Pages** |

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| | | | |
|:---|:---|:---|:---|
| **1** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> RTW Investments, LP | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> RTW Investments, LP | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> RTW Investments, LP |
| **2** | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp; (a) ◻<br> (b) ◻ |
| **3** | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY |
| **4** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> Delaware |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **5** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE VOTING POWER<br> - 0 - | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE VOTING POWER<br> - 0 - |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **6** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED VOTING POWER<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED VOTING POWER<br> 3,643,114 Shares |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **7** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE DISPOSITIVE POWER<br> - 0 - | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE DISPOSITIVE POWER<br> - 0 - |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **8** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED DISPOSITIVE POWER<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED DISPOSITIVE POWER<br> 3,643,114 Shares |
| **9** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 3,643,114 Shares |
| **10** | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;◻ |
| **11** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.3% | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.3% | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.3% |
| **12** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> PN, IA | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> PN, IA | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> PN, IA |

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| | | |
|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 3 of 8 Pages** |

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| | | | |
|:---|:---|:---|:---|
| **1** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> Roderick Wong | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> Roderick Wong | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; NAMES OF REPORTING PERSONS<br> Roderick Wong |
| **2** | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | &nbsp;&nbsp; (a) ◻<br> (b) ◻ |
| **3** | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;SEC USE ONLY |
| **4** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> United States | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> United States | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CITIZENSHIP OR PLACE OF ORGANIZATION<br> United States |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **5** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE VOTING POWER<br> - 0 - | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE VOTING POWER<br> - 0 - |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **6** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED VOTING POWER<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED VOTING POWER<br> 3,643,114 Shares |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **7** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE DISPOSITIVE POWER<br> - 0 - | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SOLE DISPOSITIVE POWER<br> - 0 - |
| &nbsp;&nbsp;NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH<br> REPORTING<br> PERSON WITH | **8** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED DISPOSITIVE POWER<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SHARED DISPOSITIVE POWER<br> 3,643,114 Shares |
| **9** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 3,643,114 Shares | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br> 3,643,114 Shares |
| **10** | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES | &nbsp;&nbsp;◻ |
| **11** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.3% | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.3% | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)<br> 6.3% |
| **12** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> IN, HC | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> IN, HC | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; TYPE OF REPORTING PERSON<br> IN, HC |

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| | | |
|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 4 of 8 Pages** |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 1(a).** | &nbsp;&nbsp;**NAME OF ISSUER.** |
|  | &nbsp;&nbsp;The name of the issuer is Mirati Therapeutics, Inc. (the "<u>Company</u>"). |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 1(b).** | &nbsp;&nbsp;**ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:** |
|  | &nbsp;&nbsp;The Company's principal executive offices are located at 3545 Cray Court, San Diego, California 92121. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(a).** | &nbsp;&nbsp;**NAME OF PERSON FILING:** |
|  | &nbsp;&nbsp;This statement is filed by: |
| &nbsp;&nbsp; &nbsp;&nbsp;(i) | &nbsp;&nbsp; RTW Investments, LP ("<u>RTW Investments</u>"), a Delaware limited partnership, and the investment adviser to certain funds (the "<u>RTW Funds</u>"), with respect to the Shares (as defined in Item 2(d) below) directly held by the RTW Funds; and<br>|
| &nbsp;&nbsp; &nbsp;&nbsp;(ii) | &nbsp;&nbsp;Mr. Roderick Wong ("<u>Mr. Wong</u>"), the Managing Partner and Chief Investment Officer of RTW Investments, with respect to the Shares directly held by the RTW Funds. |
|  | &nbsp;&nbsp;The foregoing persons are hereinafter sometimes collectively referred to as the "<u>Reporting Persons</u>." |
|  | &nbsp;&nbsp;The filing of this statement should not be construed as an admission that any of the foregoing persons or any Reporting Person is, for the purposes of Section 13 of the Act, the beneficial owner of the Shares reported herein. |

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| |
|:---|
| &nbsp;&nbsp;**Item 2(b).** |
| &nbsp;&nbsp; &nbsp;&nbsp;The address of the business office of each of the Reporting Persons is 40 10<sup>th</sup> Avenue, Floor 7, New York, New York 10014. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(c).** | &nbsp;&nbsp;**CITIZENSHIP:** |
|  | &nbsp;&nbsp;RTW Investments is a Delaware limited partnership. Mr. Wong is a citizen of the United States. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 2(d).** | &nbsp;&nbsp;**TITLE OF CLASS OF SECURITIES:** |
|  | &nbsp;&nbsp;Common Stock, par value $0.001 per share (the "<u>Shares</u>"). |

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|:---|:---|
| &nbsp;&nbsp;**Item 2(e).** | &nbsp;&nbsp;**CUSIP NUMBER:** |
|  | &nbsp;&nbsp;60468T105 |

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| | | |
|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 5 of 8 Pages** |

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|:---|:---|
| &nbsp;&nbsp;**Item 3.** | &nbsp;&nbsp;**IF THIS STATEMENT IS FILED PURSUANT TO §§ 240.13d-1(b) OR 240.13d-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A:** |

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(a) ◻ Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o);

(b) ◻ Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c);

(c) ◻ Insurance company as defined in Section 3(a)(19) of the Act (15 U.S.C. 78c);

(d) ◻ Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

(e) ⌧ Investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

(f) ◻ Employee benefit plan or endowment fund in accordance
 with Rule 13d-1(b)(1)(ii)(F);

(g) ⌧ Parent holding company or control person in accordance
 with Rule 13d-1(b)(1)(ii)(G);

(h) ◻ Savings association as defined in Section 3(b) of the Federal Deposit Insurance
 Act (12 U.S.C. 1813);

(i) ◻ Church plan that is excluded from the definition of an investment company
 under Section 3(c)(14) of the Investment Company Act (15 U.S.C. 80a-3);

(j) ◻ Non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J);

(k) ◻ Group, in accordance with Rule 13d-1(b)(1)(ii)(K).

If filing as a non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J), please specify the type of institution: _______________________ <br>

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 4.** | &nbsp;&nbsp;**OWNERSHIP**. |
|  | &nbsp;&nbsp;The information required by Items 4(a) - (c) is set forth in Rows 5 - 11 of the cover page for each of the Reporting Persons and is incorporated herein by reference. |
|  | &nbsp;&nbsp;The percentages set forth herein are calculated based upon 57,586,881 Shares outstanding as of November 3, 2022, as reported in the Company's Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2022 with the Securities and Exchange Commission on November 8, 2022. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 5.** | &nbsp;&nbsp;**OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.** |
|  | &nbsp;&nbsp;Not applicable. |

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|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 6 of 8 Pages** |

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|:---|:---|
| &nbsp;&nbsp;**Item 6.** | &nbsp;&nbsp;**OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.** |
|  | &nbsp;&nbsp;See Item 2. The RTW Funds have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Shares reported herein. |

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|:---|:---|
| &nbsp;&nbsp;**Item 7.** | &nbsp;&nbsp;**IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.** |
|  | &nbsp;&nbsp;Not applicable. |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Item 8.** | &nbsp;&nbsp;**IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.** |
|  | &nbsp;&nbsp;Not applicable. |

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|:---|:---|
| &nbsp;&nbsp;**Item 9.** | &nbsp;&nbsp;**NOTICE OF DISSOLUTION OF GROUP.** |
|  | &nbsp;&nbsp;Not applicable. |

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|:---|:---|
| &nbsp;&nbsp;**Item 10.** | &nbsp;&nbsp;**CERTIFICATION.** |

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|:---|
| &nbsp;&nbsp;Each of the Reporting Persons hereby makes the following certification: |
| &nbsp;&nbsp;By signing below each Reporting Person certifies that, to the best of his or its knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. |

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| | | |
|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 7 of 8 Pages** |

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**SIGNATURES**

After reasonable inquiry and to the best of his or its knowledge and belief, each of the undersigned certify that the information set forth in this statement is true, complete and correct.

DATED: February 14, 2023

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| | |
|:---|:---|
| **RTW INVESTMENTS, LP** | **RTW INVESTMENTS, LP** |
| By: | /s/ Roderick Wong |
| Name: | Roderick Wong |
| Title: | Managing Partner |
| /s/ Roderick Wong | /s/ Roderick Wong |
| **RODERICK WONG** | **RODERICK WONG** |

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| | | |
|:---|:---|:---|
| **CUSIP No. 60468T105** | **13G/A** | **Page 8 of 8 Pages** |

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**EXHIBIT 1**

**JOINT FILING AGREEMENT<br> PURSUANT TO RULE 13d-1(k)**

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him or it contained herein and therein, but shall not be responsible for the completeness and accuracy of the information concerning the others, except to the extent that he or it knows or has reason to believe that such information is inaccurate.

DATE: February 14, 2023

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| | |
|:---|:---|
| **RTW INVESTMENTS, LP** | **RTW INVESTMENTS, LP** |
| By: | /s/ Roderick Wong |
| Name: | Roderick Wong |
| Title: | Managing Partner |
| /s/ Roderick Wong | /s/ Roderick Wong |
| **RODERICK WONG** | **RODERICK WONG** |

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