# EDGAR Filing Document

**Accession Number:** 0001761673
**File Stem:** 0000051931-26-000333
**Filing Date:** 2026-3
**Character Count:** 2764
**Document Hash:** 27234f7250597f269a44d5deea09fc88
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000051931-26-000333.hdr.sgml**: 20260305

**ACCESSION NUMBER**: 0000051931-26-000333

**CONFORMED SUBMISSION TYPE**: 497J

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20260305

**DATE AS OF CHANGE**: 20260305

**EFFECTIVENESS DATE**: 20260305

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** American Funds Multi-Sector Income Fund
- **CENTRAL INDEX KEY:** 0001761673

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 497J
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-228995
- **FILM NUMBER:** 26725304

**BUSINESS ADDRESS:**
- **STREET 1:** 6455 IRVINE CENTER DRIVE
- **CITY:** IRVINE
- **STATE:** CA
- **ZIP:** 92618
- **BUSINESS PHONE:** 213-486-9200

**MAIL ADDRESS:**
- **STREET 1:** 333 SOUTH HOPE STREET, 55TH FLOOR
- **CITY:** LOS ANGELES
- **STATE:** CA
- **ZIP:** 90071

## Series and Classes Contracts Data

### American Funds Multi-Sector Income Fund (Series ID: S000065032)

| Class ID   | Class Name    | Ticker Symbol   |
|:---|:---|:---|
| C000210538 | Class T       | MIAVX           |
| C000210539 | Class 529-A   | CMBKX           |
| C000210540 | Class R-5E    | RMDSX           |
| C000210541 | Class R-5     | RMDTX           |
| C000210542 | Class R-4     | RMDRX           |
| C000210543 | Class R-3     | RMDQX           |
| C000210544 | Class R-2E    | RMDPX           |
| C000210545 | Class R-2     | RMDOX           |
| C000210546 | Class R-1     | RMDNX           |
| C000210547 | Class F-3     | MIAZX           |
| C000210548 | Class F-2     | MIAYX           |
| C000210549 | Class F-1     | MIAWX           |
| C000210550 | Class C       | MIAUX           |
| C000210551 | Class A       | MIAQX           |
| C000210552 | Class 529-T   | CMBNX           |
| C000210553 | Class 529-F-1 | CMBOX           |
| C000210554 | Class 529-E   | CMBMX           |
| C000210555 | Class 529-C   | CMBLX           |
| C000210556 | Class R-6     | RMDUX           |
| C000220532 | Class 529-F-2 | CMBPX           |
| C000220533 | Class 529-F-3 | CMBQX           |

March 5, 2026

Document Control

U.S. Securities and Exchange Commission

100 F Street, NE

Washington, DC 20549

**Re: American Funds Multi-Sector Income Fund**

**File Nos. 333-228995 and 811-23409**

Dear Sir or Madam:

Pursuant to Rule 497(j), I hereby certify that no changes have been made to the forms of prospectus and Statement of Additional Information since the electronic filing on February 27, 2026 of Registrant's Post-Effective Amendment No. 9 under the Securities Act of 1933 and Amendment No. 10 under the Investment Company Act of 1940, both as amended.

Sincerely,

/s/Courtney R. Taylor

Courtney R. Taylor

Secretary