# EDGAR Filing Document

**Accession Number:** 0001239501
**File Stem:** 0001447362-23-000048
**Filing Date:** 2023-3
**Character Count:** 8639
**Document Hash:** 61ae6881c5124baae7a413bdd429a331
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001447362-23-000048.hdr.sgml**: 20230308

**ACCESSION NUMBER**: 0001447362-23-000048

**CONFORMED SUBMISSION TYPE**: 4

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20230306

**FILED AS OF DATE**: 20230308

**DATE AS OF CHANGE**: 20230308

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** MAETZOLD DEREK J
- **CENTRAL INDEX KEY:** 0001239501

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38984
- **FILM NUMBER:** 23716413

**MAIL ADDRESS:**
- **STREET 1:** 820 S. FRIENDSWOOD DRIVE
- **STREET 2:** SUITE 201
- **CITY:** FRIENDSWOOD
- **STATE:** TX
- **ZIP:** 77546
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** CASTLE BIOSCIENCES INC
- **CENTRAL INDEX KEY:** 0001447362
- **STANDARD INDUSTRIAL CLASSIFICATION:** SERVICES-MEDICAL LABORATORIES [8071]
- **IRS NUMBER:** 770701774
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 505 S FRIENDSWOOD DRIVE
- **STREET 2:** SUITE 401
- **CITY:** FRIENDSWOOD
- **STATE:** TX
- **ZIP:** 77546
- **BUSINESS PHONE:** 866-788-9007

**MAIL ADDRESS:**
- **STREET 1:** 505 S FRIENDSWOOD DRIVE
- **STREET 2:** SUITE 401
- **CITY:** FRIENDSWOOD
- **STATE:** TX
- **ZIP:** 77546

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 4

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[ ] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>MAETZOLD DEREK J<br><sub>(Last) (First) (Middle)</sub><br>C/O CASTLE BIOSCIENCES, INC.<br>505 S. FRIENDSWOOD DRIVE, SUITE 401<br><sub>(Street)</sub><br>FRIENDSWOOD, TX 77546<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2023-03-06 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [ ] 10% Owner<br>[X] Officer (give title below) [ ] Other (specify below)<br>_Pres. & Chief Exec. Officer_ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>CASTLE BIOSCIENCES INC [ CSTL ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[X] Form filed by One Reporting Person<br>[ ] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 2792 | D | 24.708<sup>(2)</sup> | 163149 | D |  |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 1396 | D | 24.708<sup>(2)</sup> | 119138 | I | By The Maetzold Descendants 2020 Trust<sup>(3)</sup> |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 1396 | D | 24.708<sup>(2)</sup> | 108033 | I | By Derek Maetzold 2020 Irrevocable Trust<sup>(4)</sup> |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 697 | D | 24.708<sup>(2)</sup> | 23006 | I | By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk<sup>(5)</sup> |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 697 | D | 24.708<sup>(2)</sup> | 23007 | I | By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold<sup>(6)</sup> |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 697 | D | 24.708<sup>(2)</sup> | 23006 | I | By The Maetzold 2018 Remainder  Trust FBO John Derek Maetzold<sup>(7)</sup> |
| Common Stock | 2023-03-06 |  | S<sup>(1)</sup> |  | 697 | D | 24.708<sup>(2)</sup> | 22999 | I | By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold<sup>(8)</sup> |
| Common Stock |  |  |  |  |  |  |  | 130000 | I | By DJM Grantor Retained Annuity Trust No. 4<sup>(9)</sup> |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

---

### Footnotes:

(1) These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person, The Maetzold Descendants 2020 Trust, Derek Maetzold 2020 Irrevocable Trust, The Maetzold 2018 Remainder Trust f/b/o Emily Carol Kirk, The Maetzold 2018 Remainder Trust f/b/o Hannah Elizabeth Maetzold, The Maetzold 2018 Remainder Trust f/b/o John Derek Maetzold, and The Maetzold 2018 Remainder Trust f/b/o Peter Douglas Maetzold on December 12, 2022.

(2) This transaction was executed in multiple trades at prices ranging from $24.380 to $25.035, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

(3) Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.

(4) Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.

(5) Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.

(6) Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.

(7) Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.

(8) Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.

(9) Held by DJM Grantor Retained Annuity Trust No. 4 of which the Reporting Person is the trustee and beneficiary.

**Signature:** /s/ Greg Acosta, Attorney-in-fact  
**Date:** 2023-03-08

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**