# EDGAR Filing Document

**Accession Number:** 0001364608
**File Stem:** 0000940400-25-009897
**Filing Date:** 2025-11
**Character Count:** 15914
**Document Hash:** a7f8fe6ae7918f92dc4e8e8ca8d328ac
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000940400-25-009897.hdr.sgml**: 20251124

**ACCESSION NUMBER**: 0000940400-25-009897

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250930

**FILED AS OF DATE**: 20251124

**DATE AS OF CHANGE**: 20251124

**PERIOD START**: 20250930

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIRST TRUST EXCHANGE-TRADED FUND II
- **CENTRAL INDEX KEY:** 0001364608

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MA

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-21944
- **FILM NUMBER:** 251513570

**BUSINESS ADDRESS:**
- **STREET 1:** 12O EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187
- **BUSINESS PHONE:** 630-765-8000

**MAIL ADDRESS:**
- **STREET 1:** 12O EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187

## Series and Classes Contracts Data

### First Trust Nasdaq Lux Digital Health Solutions ETF (Series ID: S000075528)

| Class ID   | Class Name                                          | Ticker Symbol   |
|:---|:---|:---|
| C000234707 | First Trust Nasdaq Lux Digital Health Solutions ETF | EKG             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** First Trust Exchange-Traded Fund II

- **b. Investment Company Act file number:** 811-21944

- **c. CIK number of Registrant:** 0001364608

- **d. LEI of Registrant:** 549300HY3NFBU00W8S30

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 120 East Liberty Drive

  - **City:** Wheaton

  - **State:** IL

  - **Foreign country:** US

  - **Zip / Postal Code:** 60187

  - **Telephone number:** 630-765-8000

**Item A.2. Information about the Series.**

- **a. Name of Series:** First Trust Nasdaq Lux Digital Health Solutions ETF

- **b. EDGAR series identifier (if any):** S000075528

- **c. LEI of Series:** 549300D67CSMMN7O4494

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-09-30

- **b. Date as of which information is reported:** 2025-09-30

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $2611650.19

**Total Liabilities:** $1410.01

**Net Assets:** $2610240.18

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000234707 | -4.32%               | 1.99%                | -0.06%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $0.00                    | $-152549.37                                |
| Month 2  | $235715.38               | $-166438.75                                |
| Month 3  | $-44367.58               | $44975.13                                  |

### Schedule of Portfolio Investments

| Name                           | Title                           | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Exact Sciences Corp            | Exact Sciences Corp             | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |      1805 | NS      | $98751.55     | 3.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Hims & Hers Health Inc         | Hims & Hers Health Inc          | CUSIP: 433000106<br>LEI: 254900V041EIVTSB6D58 | Long             | EC               | CORP              | US        |      2195 | NS      | $124500.40    | 4.77%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc               | 10X Genomics Inc                | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |      1012 | NS      | $11830.28     | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc                     | ResMed Inc                      | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |       762 | NS      | $208582.26    | 7.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Dexcom Inc                     | Dexcom Inc                      | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |      2775 | NS      | $186729.75    | 7.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                   | Doximity Inc                    | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1395 | NS      | $102044.25    | 3.91%             |  |  |  | No            |                  1 | On Loan: No      |
| iRhythm Technologies Inc       | iRhythm Technologies Inc        | CUSIP: 450056106<br>LEI: 549300FJI72RJGDQS384 | Long             | EC               | CORP              | US        |       289 | NS      | $49705.11     | 1.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Beta Bionics Inc               | Beta Bionics Inc                | CUSIP: 08659B102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       551 | NS      | $10948.37     | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health Inc            | Guardant Health Inc             | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |      1448 | NS      | $90471.04     | 3.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Tandem Diabetes Care Inc       | Tandem Diabetes Care Inc        | CUSIP: 875372203<br>LEI: 549300JEPFOD0K4D3I05 | Long             | EC               | CORP              | US        |       700 | NS      | $8498.00      | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| QIAGEN NV                      | QIAGEN NV                       | CUSIP: 000000000<br>LEI: 54930036WK3GMCN17Z57 | Long             | EC               | CORP              | NL        |      2248 | NS      | $100440.64    | 3.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Privia Health Group Inc        | Privia Health Group Inc         | CUSIP: 74276R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1068 | NS      | $26593.20     | 1.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corp          | Twist Bioscience Corp           | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |       525 | NS      | $14773.50     | 0.57%             |  |  |  | No            |                  1 | On Loan: No      |
| MSILF Treasury Portfolio       | MSILF Treasury Portfolio        | CUSIP: 61747C582<br>LEI: 549300D1XR6GP7EZ0T47 | Long             | STIV             | RF                | US        |      4065 | NS      | $4065.19      | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| QuidelOrtho Corp               | QuidelOrtho Corp                | CUSIP: 219798105<br>LEI: 549300YU8CMO9HF53113 | Long             | EC               | CORP              | US        |       544 | NS      | $16020.80     | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Masimo Corp                    | Masimo Corp                     | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |       488 | NS      | $72004.40     | 2.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc                     | Natera Inc                      | CUSIP: 632307104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       621 | NS      | $99962.37     | 3.83%             |  |  |  | No            |                  1 | On Loan: No      |
| NeoGenomics Inc                | NeoGenomics Inc                 | CUSIP: 64049M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1339 | NS      | $10337.08     | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc             | IQVIA Holdings Inc              | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |      1096 | NS      | $208174.24    | 7.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Establishment Labs Holdings In | Establishment Labs Holdings Inc | CUSIP: 000000000<br>LEI: 549300BCBQ714JNJ7V58 | Long             | EC               | CORP              | CR        |       363 | NS      | $14879.37     | 0.57%             |  |  |  | No            |                  1 | On Loan: No      |
| TransMedics Group Inc          | TransMedics Group Inc           | CUSIP: 89377M109<br>LEI: 549300060GVOSMWARH50 | Long             | EC               | CORP              | US        |       292 | NS      | $32762.40     | 1.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Alphatec Holdings Inc          | Alphatec Holdings Inc           | CUSIP: 02081G201<br>LEI: 549300EZE8CQ8K65FS24 | Long             | EC               | CORP              | US        |      1779 | NS      | $25866.66     | 0.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc         | Intuitive Surgical Inc          | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |       442 | NS      | $197675.66    | 7.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp  | Adaptive Biotechnologies Corp   | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |      1789 | NS      | $26763.44     | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc              | Veeva Systems Inc               | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |       777 | NS      | $231476.07    | 8.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Hinge Health Inc               | Hinge Health Inc                | CUSIP: 433313103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       199 | NS      | $9766.92      | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Schrodinger Inc/United States  | Schrodinger Inc/United States   | CUSIP: 80810D103<br>LEI: 984500044BAE4791E559 | Long             | EC               | CORP              | US        |       587 | NS      | $11775.22     | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                    | Hologic Inc                     | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |      1557 | NS      | $105081.93    | 4.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                   | Veracyte Inc                    | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |       707 | NS      | $24271.31     | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc           | Align Technology Inc            | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |       736 | NS      | $92161.92     | 3.53%             |  |  |  | No            |                  1 | On Loan: No      |
| LifeStance Health Group Inc    | LifeStance Health Group Inc     | CUSIP: 53228F101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2257 | NS      | $12413.50     | 0.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                   | Illumina Inc                    | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |      1046 | NS      | $99338.62     | 3.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corp                   | Insulet Corp                    | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |       308 | NS      | $95088.84     | 3.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc    | Inspire Medical Systems Inc     | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |       257 | NS      | $19069.40     | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Teladoc Health Inc             | Teladoc Health Inc              | CUSIP: 87918A105<br>LEI: 549300I2PVFBC9MFAC61 | Long             | EC               | CORP              | US        |      1978 | NS      | $15289.94     | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| Progyny Inc                    | Progyny Inc                     | CUSIP: 74340E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       677 | NS      | $14569.04     | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Medical Inc             | Globus Medical Inc              | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |      1276 | NS      | $73076.52     | 2.80%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BioRobotics Corp       | PROCEPT BioRobotics Corp        | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       538 | NS      | $19201.22     | 0.74%             |  |  |  | No            |                  1 | On Loan: No      |
| Oscar Health Inc               | Oscar Health Inc                | CUSIP: 687793109<br>LEI: 254900AE8KDLFDOPKZ19 | Long             | EC               | CORP              | US        |      2466 | NS      | $46681.38     | 1.79%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-11-24

**Name of Applicant:** First Trust Exchange-Traded Fund II

**Signature:** Derek Maltbie

**Name of Signer:** Derek Maltbie

**Title:** Treasurer, Chief Financial Officer and Chief Accounting Officer