# EDGAR Filing Document

**Accession Number:** 0001831963
**File Stem:** 0001641172-25-022100
**Filing Date:** 2025-8
**Character Count:** 10388
**Document Hash:** be76d0694f610dbff5f16b95e536c05d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001641172-25-022100.hdr.sgml**: 20250804

**ACCESSION NUMBER**: 0001641172-25-022100

**CONFORMED SUBMISSION TYPE**: 3

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250729

**FILED AS OF DATE**: 20250804

**DATE AS OF CHANGE**: 20250804

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Ally Bridge Group (NY) LLC
- **CENTRAL INDEX KEY:** 0001822947

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-41429
- **FILM NUMBER:** 251181890

**BUSINESS ADDRESS:**
- **STREET 1:** 430 PARK AVENUE, 12TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022
- **BUSINESS PHONE:** 6468299830

**MAIL ADDRESS:**
- **STREET 1:** 430 PARK AVENUE, 12TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Yu Fan
- **CENTRAL INDEX KEY:** 0001668029

**ORGANIZATION NAME:**

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-41429
- **FILM NUMBER:** 251181889

**MAIL ADDRESS:**
- **STREET 1:** SUITE 3902, 39/F, EAST TOWER
- **STREET 2:** CHEUNG KONG CNTR II, 10 HARCOURT ROAD
- **CITY:** CENTRAL, HONG KONG
- **STATE:** K3
- **ZIP:** 000000
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** ABG Management Ltd.
- **CENTRAL INDEX KEY:** 0001832106

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-41429
- **FILM NUMBER:** 251181892

**BUSINESS ADDRESS:**
- **STREET 1:** 15 QUEENS ROAD CENTRAL, UNIT 3002-3004
- **STREET 2:** 30TH FLOOR, GLOUCESTER TWR, THE LANDMARK
- **CITY:** HONG KONG
- **STATE:** F4
- **ZIP:** 0000000000
- **BUSINESS PHONE:** 852 31219699

**MAIL ADDRESS:**
- **STREET 1:** 15 QUEENS ROAD CENTRAL, UNIT 3002-3004
- **STREET 2:** 30TH FLOOR, GLOUCESTER TWR, THE LANDMARK
- **CITY:** HONG KONG
- **STATE:** F4
- **ZIP:** 0000000000
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Ally Bridge MedAlpha Master Fund L.P.
- **CENTRAL INDEX KEY:** 0001831963

**ORGANIZATION NAME:**
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 3
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-41429
- **FILM NUMBER:** 251181891

**BUSINESS ADDRESS:**
- **STREET 1:** 15 QUEENS ROAD CENTRAL, UNIT 3002-3004
- **STREET 2:** 30TH FLOOR, GLOUCESTER TWR, THE LANDMARK
- **CITY:** HONG KONG
- **STATE:** F4
- **ZIP:** 0000000000
- **BUSINESS PHONE:** 852 31219699

**MAIL ADDRESS:**
- **STREET 1:** 15 QUEENS ROAD CENTRAL, UNIT 3002-3004
- **STREET 2:** 30TH FLOOR, GLOUCESTER TWR, THE LANDMARK
- **CITY:** HONG KONG
- **STATE:** F4
- **ZIP:** 0000000000
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ProMIS Neurosciences Inc.
- **CENTRAL INDEX KEY:** 0001374339
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** Z4
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** SUITE 200, 1920 YONGE STREET
- **CITY:** TORONTO
- **STATE:** A6
- **ZIP:** M4S 3E2
- **BUSINESS PHONE:** 416-847-6898

**MAIL ADDRESS:**
- **STREET 1:** SUITE 200, 1920 YONGE STREET
- **CITY:** TORONTO
- **STATE:** A6
- **ZIP:** M4S 3E2

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMORFIX LIFE SCIENCES LTD
- **DATE OF NAME CHANGE:** 20060831

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 3

### INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>ABG Management Ltd.<br><sub>(Last) (First) (Middle)</sub><br>

#3902, 39/F, E TOWER,<br>10 HARCOURT RD CTR<br><sub>(Street)</sub><br>HONG KONG, K3 0000000000<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>ProMIS Neurosciences Inc. [ PMN ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2025-07-29 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Ally Bridge MedAlpha Master Fund L.P.<br><sub>(Last) (First) (Middle)</sub><br>C/O MAPLES CORPORATE SERVICES LIMITED,<br>P.O. BOX 309, UGLAND HOUSE,<br><sub>(Street)</sub><br>GRAND CAYMAN, E9 <br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>ProMIS Neurosciences Inc. [ PMN ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2025-07-29 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Ally Bridge Group (NY) LLC<br><sub>(Last) (First) (Middle)</sub><br>430 PARK AVENUE,<br>12TH FLOOR,<br><sub>(Street)</sub><br>NEW YORK,, NY 10022<br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>ProMIS Neurosciences Inc. [ PMN ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2025-07-29 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Yu Fan<br><sub>(Last) (First) (Middle)</sub><br>

#3902, 39/F, E TOWER,<br>10 HARCOURT RD CTR<br><sub>(Street)</sub><br>HONG KONG,  <br><sub>(City) (State) (Zip)</sub> | **3. Issuer Name and Ticker or Trading Symbol**<br>ProMIS Neurosciences Inc. [ PMN ] | **5. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  |
| **2. Date of Event Requiring Statement (Month/Day/Year)**<br>2025-07-29 | **4. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director   [X] 10% Owner<br>[ ] Officer (give title below)   [ ] Other (specify below)<br>_ _ | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities Beneficially Owned

---

|  |  |  |  |
| --- | --- | --- | --- |
| 1. Title of Security | 2. Amount of Securities Beneficially Owned | 3. Ownership Form | 4. Nature of Indirect Beneficial Ownership |
| Common Shares | 6058738 | I | See Footnote<sup>(1)</sup> |

---

## Table II - Derivative Securities Beneficially Owned

---

|  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Date Exercisable and Expiration Date (Month/Day/Year) | 2. Date Exercisable and Expiration Date (Month/Day/Year) | 3. Title and Amount of Underlying Securities | 3. Title and Amount of Underlying Securities | 4. Conversion or Exercise Price | 5. Ownership Form | 6. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 4. Conversion or Exercise Price | 5. Ownership Form | 6. Nature of Indirect Beneficial Ownership |
| Warrants | 2024-02-21 | 2029-02-21 | Common Shares | 1066674 | $1.75 | I | See Footnote<sup>(1)</sup> |
| Warrants | 2024-07-26 | <sup>(2)</sup> | Common Shares | 1274759 | $0.01 | I | See Footnote<sup>(1)</sup> |
| Warrants | 2025-07-29 | 2030-07-29 | Common Shares | 7348604 | $1.25 | I | See Footnote<sup>(1)</sup> |

---

### Footnotes:

(1) These securities are held of record by Ally Bridge MedAlpha Master Fund L.P. Mr. Fan Yu is the controlling stockholder of ABG Management Ltd., which is the sole member of Ally Bridge Group (NY) LLC, which manages the investments of Ally Bridge MedAlpha Master Fund L.P. As such, each of the foregoing entities and Mr. Fan Yu may be deemed to share beneficial ownership of the securities held of record by Ally Bridge MedAlpha Master Fund L.P. Each of them disclaims beneficial ownership of such securities.

(2) The warrants will expire when exercised in full.

**Signature:** ABG Management Ltd., By: /s/ Fan Yu, Director  
**Date:** 2025-08-04

**Signature:** Ally Bridge MedAlpha Master Fund L.P., By: Ally Bridge Group (NY) LLC, its manager, By: ABG Management Ltd., its managing member, By: /s/ Fan Yu, Director  
**Date:** 2025-08-04

**Signature:** Ally Bridge Group (NY) LLC, By: ABG Management Ltd., its managing member, By: /s/ Fan Yu, Director  
**Date:** 2025-08-04

**Signature:** /s/ Fan Yu  
**Date:** 2025-08-04

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**