# EDGAR Filing Document

**Accession Number:** 0001894562
**File Stem:** 0001628280-25-029646
**Filing Date:** 2025-6
**Character Count:** 7259
**Document Hash:** b01fb5a12aebbda0077c44204f8a5d6c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001628280-25-029646.hdr.sgml**: 20250605

**ACCESSION NUMBER**: 0001628280-25-029646

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 13

**CONFORMED PERIOD OF REPORT**: 20250604

**ITEM INFORMATION**: Submission of Matters to a Vote of Security Holders

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20250605

**DATE AS OF CHANGE**: 20250605

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Prime Medicine, Inc.
- **CENTRAL INDEX KEY:** 0001894562
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-41536
- **FILM NUMBER:** 251027224

**BUSINESS ADDRESS:**
- **STREET 1:** 60 FIRST ST.
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02141
- **BUSINESS PHONE:** 617-465-0013

**MAIL ADDRESS:**
- **STREET 1:** 60 FIRST ST.
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02141

?xml version='1.0' encoding='ASCII'? prme-20250604

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

___________________________________

**FORM 8-K**

___________________________________

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d)**

**of the Securities Exchange Act of 1934**

**June 4, 2025**

**Date of Report (date of earliest event reported)**

___________________________________

**Prime Medicine, Inc.**

**(Exact name of registrant as specified in its charter)**

___________________________________

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| | | |
|:---|:---|:---|
| **Delaware** | **001-41536** | **84-3097762** |
| **(State or other jurisdiction of incorporation)** | **(Commission File Number)** | **(I.R.S. Employer Identification No.)** |
| **60 First Street**<br>**Cambridge, MA** |  | **02141** |
| **(Address of principal executive offices)** |  | **(Zip code)** |
| **(617) 465-0013** | **(617) 465-0013** | **(617) 465-0013** |
| **(Registrant's telephone number, including area code)** | **(Registrant's telephone number, including area code)** | **(Registrant's telephone number, including area code)** |
| **(Former name or former address, if changed since last report)** | **(Former name or former address, if changed since last report)** | **(Former name or former address, if changed since last report)** |

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___________________________________

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

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| | | |
|:---|:---|:---|
| Securities registered pursuant to Section 12(b) of the Act: | Securities registered pursuant to Section 12(b) of the Act: | Securities registered pursuant to Section 12(b) of the Act: |
| **Title of each class** | **Trading symbol(s)** | **Name of each exchange on which registered** |
| Common stock, par value $.00001 per share | PRME | The Nasdaq Global Market |

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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule12b-2 of the Securities Exchange Act of 1934 (§250.12b-2 of this chapter).

Emerging growth company&nbsp;&nbsp;&nbsp;&nbsp;☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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**Item 5.07. Submission of Matters to a Vote of Security Holders.**

On June 4, 2025, Prime Medicine, Inc. (the "Company") held its 2025 annual meeting of stockholders (the "Annual Meeting") in a virtual meeting format via live webcast. Proxies were solicited pursuant to the Company's definitive proxy statement (the "Proxy Statement") filed on April 22, 2025 with the Securities and Exchange Commission under Section 14(a) of the Securities Exchange Act of 1934, as amended. As of the close of business on April 8, 2025, the record date for the Annual Meeting, the number of shares of the Company's common stock, $0.00001 par value per share ("Common Stock"), outstanding and entitled to vote at the Annual Meeting was 131,160,842. The number of shares of Common Stock present in person or by remote communication, if applicable, or represented by valid proxy at the Annual Meeting was 98,093,739, thus establishing a quorum for the transaction of business at the Annual Meeting. Shares present virtually during the Annual Meeting were considered shares of Common Stock represented in person at the Annual Meeting. Each share of Common Stock was entitled to one vote with respect to matters submitted to the Company's stockholders at the Annual Meeting.

At the Annual Meeting, the Company's stockholders voted on the following matters, all of which were described in the Proxy Statement: (i) to elect Thomas Cahill, M.D., Ph.D. and Robert Nelsen as Class III Directors, each to serve until the Company's 2028 annual meeting of stockholders, and until his respective successor shall have been duly elected and qualified, or until his earlier death, resignation or removal ("Proposal 1") and (ii) to ratify the appointment of PricewaterhouseCoopers LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2025 ("Proposal 2"). The final voting results are set forth below.

Proposal 1 – Each of the following nominees was elected as a Class III Director to serve until the Company's 2028 annual meeting of stockholders, and until his respective successor shall have been duly elected and qualified, or until his earlier death, resignation or removal, based on the following votes:

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| | | | |
|:---|:---|:---|:---|
| **Class III Director Nominee** | **For** | **Withheld** | **Broker Non-Votes** |
| Thomas Cahill, M.D., Ph.D. | 74,446,103 | 8,336,569 | 15,311,067 |
| Robert Nelsen | 70,607,668 | 12,175,004 | 15,311,067 |

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Proposal 2 – The appointment of PricewaterhouseCoopers LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2025 was ratified, based on the following votes:

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| | | |
|:---|:---|:---|
| **For** | **Against** | **Abstentions** |
| 98,008,974 | 42,555 | 42,210 |

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**SIGNATURE**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: June 5, 2025

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| | |
|:---|:---|
| Prime Medicine, Inc. | Prime Medicine, Inc. |
| By: | /s/ Allan Reine |
| Name: | Allan Reine, M.D. |
| Title: | Chief Executive Officer |

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