# EDGAR Filing Document

**Accession Number:** 0001688757
**File Stem:** 0001688757-23-000024
**Filing Date:** 2023-3
**Character Count:** 28959
**Document Hash:** f36cea3cc8caba1acd05cd39e94ed7ac
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001688757-23-000024.hdr.sgml**: 20230301

**ACCESSION NUMBER**: 0001688757-23-000024

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 4

**FILED AS OF DATE**: 20230301

**DATE AS OF CHANGE**: 20230301

**EFFECTIVENESS DATE**: 20230301

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ESTABLISHMENT LABS HOLDINGS INC.
- **CENTRAL INDEX KEY:** 0001688757
- **STANDARD INDUSTRIAL CLASSIFICATION:** ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
- **IRS NUMBER:** 981436377

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-270196
- **FILM NUMBER:** 23694810

**BUSINESS ADDRESS:**
- **STREET 1:** PO BOX 3140, COMMERCE HOUSE
- **STREET 2:** WICKHAMS CAY 1, ROAD TOWN
- **CITY:** TORTOLA
- **STATE:** D8
- **ZIP:** VG1110
- **BUSINESS PHONE:** 50624342400

**MAIL ADDRESS:**
- **STREET 1:** PO BOX 3140, COMMERCE HOUSE
- **STREET 2:** WICKHAMS CAY 1, ROAD TOWN
- **CITY:** TORTOLA
- **STATE:** D8
- **ZIP:** VG1110

Registration No. 333-

&nbsp;&nbsp;&nbsp;&nbsp;

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| | | |
|:---|:---|:---|
| **UNITED STATES <br>SECURITIES AND EXCHANGE COMMISSION** | **UNITED STATES <br>SECURITIES AND EXCHANGE COMMISSION** | **UNITED STATES <br>SECURITIES AND EXCHANGE COMMISSION** |
| **Washington, D.C. 20549** | **Washington, D.C. 20549** | **Washington, D.C. 20549** |
| **FORM S-8** | **FORM S-8** | **FORM S-8** |
| **REGISTRATION STATEMENT** <br>***UNDER***<br> ***THE SECURITIES ACT OF 1933*** | **REGISTRATION STATEMENT** <br>***UNDER***<br> ***THE SECURITIES ACT OF 1933*** | **REGISTRATION STATEMENT** <br>***UNDER***<br> ***THE SECURITIES ACT OF 1933*** |
| **Establishment Labs Holdings Inc.** | **Establishment Labs Holdings Inc.** | **Establishment Labs Holdings Inc.** |
| **(Exact name of Registrant as specified in its charter)** | **(Exact name of Registrant as specified in its charter)** | **(Exact name of Registrant as specified in its charter)** |
| **British Virgin Islands** | | **Not applicable** |
| **(State or other jurisdiction of<br>incorporation or organization)** | | **(I.R.S. Employer<br>Identification Number)** |
| | **Building B15 and 25<br>Coyol Free Zone<br>Alajuela<br>Costa Rica** | |
| **(Address of principal executive offices including zip code)** | **(Address of principal executive offices including zip code)** | **(Address of principal executive offices including zip code)** |
| **2018 EQUITY INCENTIVE PLAN**<br>**2018 EMPLOYEE SHARE PURCHASE PLAN** | **2018 EQUITY INCENTIVE PLAN**<br>**2018 EMPLOYEE SHARE PURCHASE PLAN** | **2018 EQUITY INCENTIVE PLAN**<br>**2018 EMPLOYEE SHARE PURCHASE PLAN** |
| **(Full title of the plans)** | **(Full title of the plans)** | **(Full title of the plans)** |
| | **Rajbir S. Denhoy<br>Motiva USA LLC<br>16192 Coastal Highway<br>Lewes, DE 19958<br>+506 2434 2400** | |
| **(Name, address, and telephone number, including area code, of agent for service)** | **(Name, address, and telephone number, including area code, of agent for service)** | **(Name, address, and telephone number, including area code, of agent for service)** |
|  | Copy to: |  |
|  | **Shelly A. Heyduk**<br>**O'Melveny & Myers LLP**<br>**610 Newport Center Drive, 17th Floor**<br>**Newport Beach, CA 92660**<br>**(949) 823-6900** |  |

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Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer", "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act.

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| | |
|:---|:---|
| Large accelerated filer 🗷 | Accelerated filer ◻ |
| Non-accelerated filer ◻ | Smaller reporting company ◻ |
| | Emerging growth company ◻ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ◻

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**PART I**

**INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS**

The information specified in Item 1 and Item 2 of Part I of Form S-8 is omitted from this Registration Statement on Form S-8 (the "**Registration Statement**") in accordance with the provisions of Rule 428 under the Securities Act of 1933, as amended (the "**Securities Act**"), and the introductory note to Part I of Form S-8. The documents containing the information specified in Part I of Form S-8 will be delivered to the participants in the equity benefit plans covered by this Registration Statement as specified by Rule 428(b)(1) under the Securities Act.

**PART II**

**INFORMATION REQUIRED IN THE REGISTRATION STATEMENT**

**Item 3.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Incorporation of Documents by Reference</u>.**

&nbsp;&nbsp;&nbsp;&nbsp;Establishment Labs Holdings Inc. (the "**Registrant**") hereby incorporates by reference into this Registration Statement the following documents and information heretofore filed with the Securities and Exchange Commission (the "**Commission**"):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)The Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2022, filed with the Commission on March 1, 2023 pursuant to Section 13 of the Securities Exchange Act of 1934, as amended (the "**Exchange Act**") (File No. 001-38593); and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)The description of the Registrant's Common Shares contained in the Registrant's Registration Statement on Form S-1 (File No. 333-225791) initially filed with the Commission on June 21, 2018, as modified by the description of the Registrant's Common Shares contained in Exhibit 4.8 of the Registrant's Annual Report for the year ended December 31, 2019, filed with the Commission on March 16, 2020, and any other amendment or report filed for the purpose of updating such description.

&nbsp;&nbsp;&nbsp;&nbsp;All documents filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act on or after the date of this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement that indicates that all securities offered have been sold or that deregisters all securities then remaining unsold shall be deemed to be incorporated by reference in this Registration Statement and to be part hereof from the date of filing of such documents; provided, however, that documents or information deemed to have been furnished and not filed in accordance with the rules of the Commission shall not be deemed incorporated by reference into this Registration Statement. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any subsequently filed document which also is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.

**Item 4.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Description of Securities</u>.**

Not applicable.

**Item 5.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Interests of Named Experts and Counsel</u>.**

Not applicable.

**Item 6.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Indemnification of Directors and Officers</u>.**

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The BVI Business Companies Act, 2004, as amended, or the BVI Act, and the Registrant's amended and restated memorandum and articles of association provide for the indemnification of its directors against all losses or liabilities incurred or sustained by him or her as a director of the Registrant in defending any proceedings, whether civil or criminal provided that this indemnity only applies if he or she acted honestly and in good faith with a view to the Registrant's best interests and, with respect to any criminal action, he or she must have had no reasonable cause to believe his or her conduct was unlawful.

In addition to the indemnification required in the Registrant's amended and restated memorandum and articles of association, the Registrant has entered into indemnification agreements with each of its current directors and officers. These agreements provide indemnification for certain expenses and liabilities incurred in connection with any action, suit, proceeding, or alternative dispute resolution mechanism, or hearing, inquiry, or investigation that may lead to the foregoing, to which they are a party, or are threatened to be made a party, by reason of the fact that they are or were a director, officer, employee, agent, or fiduciary of the Registrant, or any of its subsidiaries, by reason of any action or inaction by them while serving as an officer, director, agent, or fiduciary, or by reason of the fact that they were serving at its request as a director, officer, employee, agent, or fiduciary of another entity. In the case of an action or proceeding by, or in the right of, the Registrant or any of its subsidiaries, no indemnification will be provided for any claim where a court determines that the indemnified party is prohibited from receiving indemnification. The Registrant believes that these article provisions and indemnification agreements are necessary to attract and retain qualified persons as directors and officers. The Registrant also maintains directors' and officers' liability insurance.

The limitation of liability and indemnification provisions in the Registrant's amended and restated memorandum and articles of association may discourage shareholders from bringing a lawsuit against directors for breach of their fiduciary duties. They may also reduce the likelihood of derivative litigation against directors and officers, even though an action, if successful, might benefit the Registrant or its shareholders. A shareholder's investment may be harmed to the extent the Registrant pays the costs of settlement and damage awards against directors and officers pursuant to these indemnification provisions.

See also the undertakings set out in response to Item 9 herein.

**Item 7.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Exemption from Registration Claimed</u>.**

Not applicable.

**Item 8.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Exhibits</u>.**

&nbsp;&nbsp;&nbsp;&nbsp;See Exhibit Index immediately preceding the Signature Page.

**Item 9.**&nbsp;&nbsp;&nbsp;&nbsp;**<u>Undertakings</u>.**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A.&nbsp;&nbsp;&nbsp;&nbsp;The undersigned Registrant hereby undertakes:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;&nbsp;&nbsp;&nbsp;To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i)&nbsp;&nbsp;&nbsp;&nbsp;to include any prospectus required by Section 10(a)(3) of the Securities Act;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii)&nbsp;&nbsp;&nbsp;&nbsp;to reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the SEC pursuant to Rule 424(b) if, in the aggregate, the changes in volume and

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price represent no more than a 20 percent change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective registration statement; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii)&nbsp;&nbsp;&nbsp;&nbsp;to include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement.

Provided, however, that paragraphs (A)(1)(i) and (A)(1)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in this Registration Statement.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;&nbsp;&nbsp;&nbsp;That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;&nbsp;&nbsp;&nbsp;To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;B.&nbsp;&nbsp;&nbsp;&nbsp;The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;C.&nbsp;&nbsp;&nbsp;&nbsp;Insofar as indemnification for liabilities arising under the Securities Act may be permitted to the Registrant's directors, officers and controlling persons pursuant to applicable law, the Registrant's Amended and Restated Memorandum and Articles of Association or indemnification agreements, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person in a successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered hereunder, the Registrant will, unless in the opinion of the Registrant's counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question of whether such indemnification by the Registrant is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

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**INDEX TO EXHIBITS**

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| | |
|:---|:---|
| **Exhibit Number** | **Description** |
| 4.1<sup>(1)</sup> | <u>[2018 Equity Incentive Plan and related form agreements.](http://www.sec.gov/Archives/edgar/data/1688757/000162828018009153/exhibit103s-1a1.htm)</u> |
| 4.2<sup>(2)</sup> | <u>[2018 Employee Share Purchase Plan and related form agreements.](http://www.sec.gov/Archives/edgar/data/1688757/000162828018009153/exhibit104s-1a1.htm)</u> |
| 5.1 | <u>[Opinion of Conyers Dill & Pearman](exhibit512023.htm)</u> |
| 23.1 | <u>[Consent of Independent Registered Public Accounting Firm.](exhibit2312023.htm)</u> |
| 23.2 | <u>[Consent of Conyers Dill & Pearman (see Exhibit 5.1).](exhibit512023.htm)</u> |
| 24.1 | <u>[Power of Attorney (included on the signature page hereto).](#i619da2eca7b140e5bb91263b5d5ee5db_10)</u> |
| 107 | <u>[Filing Fee Table.](exhibit1072023.htm)</u> |

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__________

(1)Incorporated by reference to Exhibit 10.3 filed with Amendment No. 1 to the Registrant's Registration Statement on Form S-1 (Registration No. 333-225791), filed with the Commission on July 9, 2018.

(2)Incorporated by reference to Exhibit 10.4 filed with Amendment No. 1 to the Registrant's Registration Statement on Form S-1 (Registration No. 333-225791), filed with the Commission on July 9, 2018.

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**SIGNATURES**

Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in San José, Costa Rica, on March 1, 2023.

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| | |
|:---|:---|
| **ESTABLISHMENT LABS HOLDINGS** | **ESTABLISHMENT LABS HOLDINGS** |
| By: | */s/* Juan José Chacón Quirós |
|  | Juan José Chacón Quirós<br>Chief Executive Officer and Director |

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&nbsp;&nbsp;&nbsp;&nbsp;

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**POWER OF ATTORNEY**

KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below hereby constitutes and appoints Juan José Chacón Quirós and Rajbir S. Denhoy, and each of them acting individually, as his or her true and lawful attorneys-in-fact and agents, with full power of each to act alone, with full powers of substitution and resubstitution, for him or her in his or her name, place and stead, in any and all capacities to sign any and all amendments to this Registration Statement on Form S-8 (including post-effective amendments), and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, with full power of each to act alone, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully for all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or his, her or their substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities and on the date indicated.

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| | | |
|:---|:---|:---|
| Signature | Title | Date |
| */s/* Juan José Chacón Quirós  | Chief Executive Officer and Director (Principal Executive Officer) | March 1, 2023 |
| Juan José Chacón Quirós | Chief Executive Officer and Director (Principal Executive Officer) | March 1, 2023 |
| */s/ Rajbir S. Denhoy*  | Chief Financial Officer<br>(Principal Financial and Accounting Officer) <br>(Authorized Representative in the United States) | March 1, 2023 |
| Rajbir S. Denhoy | Chief Financial Officer<br>(Principal Financial and Accounting Officer) <br>(Authorized Representative in the United States) | March 1, 2023 |
| */s/ Nicholas Lewin*  | Chairman of the Board of Directors | March 1, 2023 |
| Nicholas Lewin | Chairman of the Board of Directors | March 1, 2023 |
| */s/ Lisa N. Colleran* | Director | March 1, 2023 |
| Lisa N. Colleran | Director | March 1, 2023 |
| */s/ Dennis Condon* | Director | March 1, 2023 |
| Dennis Condon | Director | March 1, 2023 |
| */s/ Ann Custin* | Director | March 1, 2023 |
| Ann Custin | Director | March 1, 2023 |
| */s/ Leslie Gillin* | Director | March 1, 2023 |
| Leslie Gillin | Director | March 1, 2023 |
| */s/ Edward Schutter* | Director | March 1, 2023 |
| Edward Schutter | Director | March 1, 2023 |
| */s/ Bryan Slotkin* | Director | March 1, 2023 |
| Bryan Slotkin | Director | March 1, 2023 |

---

## Ex-Filing

**EXHIBIT 107**

**Calculation of Filing Fee Table**

………

Form S-8

………………………………………………..…………

Establishment Lab Holdings Inc.

<u>Table 1: Newly Registered Securities</u>

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| &nbsp;&nbsp;<br>Security Type | &nbsp;&nbsp;<br>Security Class Title | &nbsp;&nbsp;<br>Fee Calculation Rule | &nbsp;&nbsp;&nbsp;&nbsp;<br>Amount Registered(1) | &nbsp;&nbsp;&nbsp;<br>Proposed Maximum Offering Price Per Unit | &nbsp;&nbsp;<br>Maximum Aggregate Offering Price | &nbsp;&nbsp;<br>Fee Rate | &nbsp;&nbsp;<br>Amount of Registration Fee |
| Equity | Common Shares, no par value | 457(c); <br>457(h) | 750000<sup>(2)</sup> | $67.16<sup>(4)</sup> | $50370000.00 | $110.20 per $1,000,000 | $5550.77 |
| Equity | Common Shares, no par value | 457(c); <br>457(h) | 187000<sup>(3)</sup> | $57.09<sup>(5)</sup> | $10675830.00 | $110.20 per $1,000,000 | $1176.48 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Offering Amounts | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Offering Amounts | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Offering Amounts | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Offering Amounts |  | $61045830.00 |  | $6727.25 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Fee Offsets | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Fee Offsets | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Fee Offsets | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Fee Offsets |  |  |  | $0 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net Fee Due | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net Fee Due | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net Fee Due | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net Fee Due |  |  |  | $6727.25 |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)Pursuant to Rule 416(a) of the Securities Act of 1933, as amended (the "**Securities Act**"), this Registration Statement on Form S-8 (this "**Registration Statement**") shall also cover any additional shares of Establishment Labs Holdings Inc.'s (the "**Registrant**") common stock that become issuable under the Registrant's 2018 Equity Incentive Plan ("**2018 Plan**") and the Registrant's 2018 Employee Stock Purchase Plan ("**2018 ESPP**") by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without receipt of consideration that increases the number of the Registrant's outstanding shares of common stock.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)Represents an automatic annual increase of 750,000 shares on January 1, 2023 to the number of shares of the Registrant's common stock reserved for issuance under, and which annual increase is provided for in, the 2018 Plan.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)Represents an automatic annual increase of 187,000 shares on January 1, 2023 to the number of shares of the Registrant's common stock reserved for issuance under, and which annual increase is provided for in, the 2018 ESPP.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4)Estimated in accordance with Rules 457(c) and (h) of the Securities Act solely for the purpose of calculating the registration fee on the basis of $67.16 per share, which represents the average of the high and low prices of the Registrant's common stock as reported on The Nasdaq Capital Market on February 27, 2023.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5)Estimated in accordance with Rule 457(c) and (h) of the Securities Act solely for the purpose of calculating the registration fee on the basis of $57.09 per share, which represents 85% of the average of the high and low sale prices of the Registrant's common stock as reported on The Nasdaq Capital Market on February 27, 2023. Pursuant to the 2018 ESPP, the purchase price of the shares of the Registrant's common stock will be 85% of the lower of the fair market value of the Registrant's common stock on the first day of the offering period or on the exercise date.

## Exhibit 5.1

**Exhibit 5.1**

March 1, 2023

Establishment Labs Holding Inc.

Commerce House

Wickhams Cay 1,

Road Town, Tortola

British Virgin Islands

**Re:&nbsp;&nbsp;&nbsp;&nbsp;Registration Statement on Form S-8**

Ladies and Gentlemen:

We have examined the Registration Statement on Form S-8 (the "**Registration Statement**") to be filed by Establishment Labs Holdings Inc. (the "**Company**") with the Securities and Exchange Commission on or about the date hereof, in connection with the registration under the Securities Act of 1933, as amended, of an aggregate of 937,000 shares of the Company's Common Shares, no par value (the "**Shares**"), consisting of: (i) 750,000 Shares reserved for issuance under the 2018 Equity Incentive Plan and (ii) 187,000 Shares reserved for issuance under the 2018 Employee Share Purchase Plan (collectively, the "**Plans**").

On the basis of the foregoing, and in reliance thereon, we are of the opinion that, when issued and sold in the manner described in the Plans and pursuant to the agreements which accompany each grant under the Plans, the Shares will be legally and validly issued, fully-paid and non-assessable.

We consent to the use of this opinion as an exhibit to the Registration Statement, and further consent to the use of our name wherever appearing in the Registration Statement and any amendments thereto.

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| |
|:---|
| Very truly yours, |
| */s/ Conyers Dill & Pearman* |
| CONYERS DILL & PEARMAN |

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## Exhibit 23.1

**Exhibit 23.1** 

<u>Independent Registered Public Accounting Firm's Consent</u>

We consent to the incorporation by reference in the Registration Statement of Establishment Labs Holdings Inc. on Form S-3 (File No. 333-234649) and Form S-8 (File Nos. 333-254283, 333-237219, 333-230419, 333-226340 and 333-263149) of our report dated March 1, 2023, with respect to our audits of the consolidated financial statements of Establishment Labs Holdings Inc. as of December 31, 2022 and 2021 and for each of the three years in the period ended December 31, 2022 and our report dated March 1, 2023 with respect to our audit of internal control over financial reporting of Establishment Labs Holdings Inc. as of December 31, 2022 , which reports are included in this Annual Report on Form 10-K of Establishment Labs Holdings Inc. for the year ended December 31, 2022.

Our report on the effectiveness of internal control over financial reporting expressed an adverse opinion because of the existence of a material weakness.

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| |
|:---|
| /s/ Marcum LLP |
| Marcum LLP<br>Los Angeles, California<br>March 1, 2023 |

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<br>