# EDGAR Filing Document

**Accession Number:** 0000836487
**File Stem:** 0001752724-23-069870
**Filing Date:** 2023-3
**Character Count:** 35448
**Document Hash:** bea44d5df53544410594f15cc6ada405
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-23-069870.hdr.sgml**: 20230328

**ACCESSION NUMBER**: 0001752724-23-069870

**CONFORMED SUBMISSION TYPE**: 24F-2NT

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230328

**DATE AS OF CHANGE**: 20230328

**EFFECTIVENESS DATE**: 20230328

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MORGAN STANLEY INSTITUTIONAL FUND INC
- **CENTRAL INDEX KEY:** 0000836487
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** MD
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 24F-2NT
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 033-23166
- **FILM NUMBER:** 23768438

**BUSINESS ADDRESS:**
- **STREET 1:** 522 FIFTH AVENUE
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10036
- **BUSINESS PHONE:** 800-548-7786

**MAIL ADDRESS:**
- **STREET 1:** 522 FIFTH AVENUE
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10036

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MORGAN STANLEY DEAN WITTER INSTITUTIONAL FUND INC
- **DATE OF NAME CHANGE:** 19990329

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MORGAN STANLEY INSTITUTIONAL FUND INC
- **DATE OF NAME CHANGE:** 19920703

## Series and Classes Contracts Data

### ACTIVE INTERNATIONAL ALLOCATION PORTFOLIO (Series ID: S000002820)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSACX         | C000007736 |
| CLASS A    | MSIBX         | C000007737 |
| Class L    | MSLLX         | C000113799 |
| Class C    | MSAAX         | C000155887 |
| Class T    | nan           | C000178569 |
| Class IS   | MAIJX         | C000215548 |
| Class IR   | MAIHX         | C000215549 |

---

### U.S. REAL ESTATE PORTFOLIO (Series ID: S000002821)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSUSX         | C000007738 |
| CLASS A    | MUSDX         | C000007739 |
| Class L    | MSULX         | C000104301 |
| Class IS   | MURSX         | C000126911 |
| Class C    | MSURX         | C000155888 |
| Class T    | nan           | C000178570 |
| Class IR   | MRETX         | C000198814 |

---

### Inception Portfolio (Series ID: S000002825)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSSGX         | C000007744 |
| CLASS A    | MSSMX         | C000007745 |
| Class L    | MSSLX         | C000104303 |
| Class IS   | MFLLX         | C000129402 |
| Class C    | MSCOX         | C000155889 |
| Class T    | nan           | C000178571 |

---

### EMERGING MARKETS PORTFOLIO (Series ID: S000002826)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MGEMX         | C000007746 |
| CLASS A    | MMKBX         | C000007747 |
| Class L    | MSELX         | C000113803 |
| Class IS   | MMMPX         | C000126912 |
| Class C    | MSEPX         | C000155890 |
| Class T    | nan           | C000178572 |
| Class IR   | MRGEX         | C000198815 |

---

### GROWTH PORTFOLIO (Series ID: S000002828)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSEQX         | C000007750 |
| CLASS A    | MSEGX         | C000007751 |
| Class L    | MSHLX         | C000113805 |
| Class IS   | MGRPX         | C000126914 |
| Class C    | MSGUX         | C000155892 |
| Class T    | nan           | C000178573 |
| Class IR   | MGHRX         | C000198816 |

---

### GLOBAL FRANCHISE PORTFOLIO (Series ID: S000002830)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSFAX         | C000007754 |
| CLASS A    | MSFBX         | C000007755 |
| Class L    | MSFLX         | C000113809 |
| Class C    | MSGFX         | C000155893 |
| Class IS   | MGISX         | C000156276 |
| Class T    | nan           | C000178574 |

---

### INTERNATIONAL EQUITY PORTFOLIO (Series ID: S000002832)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSIQX         | C000007758 |
| CLASS A    | MIQBX         | C000007759 |
| Class L    | MSQLX         | C000113811 |
| Class IS   | MIQPX         | C000126915 |
| Class C    | MSECX         | C000155894 |
| Class T    | nan           | C000178575 |

---

### INTERNATIONAL REAL ESTATE PORTFOLIO (Series ID: S000002835)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MSUAX         | C000007763 |
| CLASS A    | IERBX         | C000007764 |
| Class L    | MSOLX         | C000113813 |
| Class IS   | MIREX         | C000126916 |
| Class C    | MSIJX         | C000155895 |
| Class T    | nan           | C000178576 |

---

### Global Real Estate Portfolio (Series ID: S000012825)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MRLAX         | C000034677 |
| Class A    | MRLBX         | C000034678 |
| Class L    | MGRLX         | C000065130 |
| Class IS   | MGREX         | C000126917 |
| Class C    | MSRDX         | C000155896 |
| Class T    | nan           | C000178577 |
| Class IR   | MRLEX         | C000198819 |

---

### International Opportunity Portfolio (Series ID: S000027992)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MIOIX         | C000085087 |
| Class L    | MIOLX         | C000085088 |
| Class A    | MIOPX         | C000085089 |
| Class IS   | MNOPX         | C000126918 |
| Class C    | MSOCX         | C000155897 |
| Class T    | nan           | C000178578 |
| Class IR   | MRNPX         | C000198820 |

---

### Advantage Portfolio (Series ID: S000027993)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MPAIX         | C000085091 |
| Class L    | MAPLX         | C000085092 |
| Class A    | MAPPX         | C000085093 |
| Class IS   | MADSX         | C000126919 |
| Class C    | MSPRX         | C000155898 |
| Class T    | nan           | C000178579 |

---

### Global Opportunity Portfolio (Series ID: S000027995)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MGGIX         | C000085098 |
| Class L    | MGGLX         | C000085099 |
| Class A    | MGGPX         | C000085100 |
| Class IS   | MGTSX         | C000126921 |
| Class C    | MSOPX         | C000155900 |
| Class T    | nan           | C000178580 |
| Class IR   | MGORX         | C000198822 |

---

### Global Infrastructure Portfolio (Series ID: S000029874)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| CLASS I    | MTIIX         | C000091816 |
| CLASS L    | MTILX         | C000091817 |
| CLASS A    | MTIPX         | C000091818 |
| Class IS   | MSGPX         | C000126922 |
| Class C    | MSGTX         | C000155901 |
| Class T    | nan           | C000178581 |
| Class IR   | MRGOX         | C000198823 |

---

### Global Insight Portfolio (Series ID: S000030616)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MIGIX         | C000094891 |
| Class L    | MIGLX         | C000094892 |
| Class A    | MIGPX         | C000094893 |
| Class C    | MSPTX         | C000155902 |
| Class T    | nan           | C000178582 |
| Class IS   | nan           | C000228507 |

---

### Global Discovery Portfolio (Series ID: S000030617)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MLDIX         | C000094895 |
| Class L    | MGDLX         | C000094896 |
| Class A    | MGDPX         | C000094897 |
| Class C    | MSPCX         | C000155903 |
| Class T    | nan           | C000178583 |
| Class IS   | nan           | C000198824 |
| Class IR   | nan           | C000198825 |

---

### International Advantage Portfolio (Series ID: S000030618)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MFAIX         | C000094898 |
| Class L    | MSALX         | C000094899 |
| Class A    | MFAPX         | C000094900 |
| Class C    | MSIAX         | C000155904 |
| Class T    | nan           | C000178584 |
| Class IS   | IDVSX         | C000198826 |

---

### Asian Equity Portfolio (Series ID: S000030707)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class I    | C000095149 |
| Class L    | C000095150 |
| Class A    | C000095151 |
| Class C    | C000155905 |

---

### Insight Portfolio (Series ID: S000035027)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MFPIX         | C000107706 |
| Class A    | MFPHX         | C000107707 |
| Class L    | MFPLX         | C000107708 |
| Class C    | MSSPX         | C000155906 |
| Class T    | nan           | C000178585 |
| Class IS   | nan           | C000198827 |

---

### Emerging Markets Fixed Income Opportunities Portfolio (Series ID: S000037168)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MEAIX         | C000114463 |
| Class A    | MEAPX         | C000114464 |
| Class L    | MEALX         | C000114466 |
| Class IS   | MRDPX         | C000126923 |
| Class C    | MSEDX         | C000155908 |
| Class T    | nan           | C000178587 |

---

### Multi-Asset Portfolio (Series ID: S000037170)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class A    | MMPPX         | C000114471 |
| Class L    | MMPLX         | C000114473 |
| Class I    | MMPIX         | C000114474 |
| Class C    | MSMEX         | C000155909 |
| Class IS   | MSPMX         | C000156277 |
| Class T    | nan           | C000178588 |

---

### Next Gen Emerging Markets Portfolio (Series ID: S000037507)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MFMIX         | C000115785 |
| Class A    | MFMPX         | C000115786 |
| Class L    | MFMLX         | C000115788 |
| Class IS   | MSRFX         | C000152578 |
| Class C    | MSFEX         | C000155910 |
| Class T    | nan           | C000178589 |

---

### Global Sustain Portfolio (Series ID: S000041864)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MGQIX         | C000129960 |
| Class A    | MGQAX         | C000129961 |
| Class L    | MGQLX         | C000129962 |
| Class IS   | MGQSX         | C000129963 |
| Class C    | MSGQX         | C000155911 |
| Class T    | nan           | C000178590 |

---

### Emerging Markets Leaders Portfolio (Series ID: S000047473)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MELIX         | C000149047 |
| Class A    | MELAX         | C000149048 |
| Class L    | nan           | C000149049 |
| Class IS   | MELSX         | C000149050 |
| Class C    | MEMLX         | C000155912 |
| Class T    | nan           | C000178591 |
| Class IR   | nan           | C000226932 |

---

### Emerging Markets Small Cap Portfolio (Series ID: S000051831)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MSEMX         | C000163116 |
| Class A    | MSEOX         | C000163117 |
| Class C    | MSESX         | C000163118 |
| Class IS   | MSETX         | C000163119 |
| Class T    | nan           | C000178592 |

---

### Asia Opportunity Portfolio (Series ID: S000051832)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MSAQX         | C000163120 |
| Class A    | MSAUX         | C000163121 |
| Class C    | MSAWX         | C000163122 |
| Class IS   | MSAYX         | C000163123 |
| Class T    | nan           | C000178593 |

---

### Global Concentrated Portfolio (Series ID: S000053786)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MLNIX         | C000169208 |
| Class A    | MLNAX         | C000169209 |
| Class C    | MLNCX         | C000169210 |
| Class IS   | MLNSX         | C000169211 |
| Class T    | nan           | C000178594 |

---

### Global Core Portfolio (Series ID: S000053787)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MLMIX         | C000169212 |
| Class A    | MLMAX         | C000169213 |
| Class C    | MLMCX         | C000169214 |
| Class IS   | MLMSX         | C000169215 |
| Class T    | nan           | C000178595 |

---

### Fundamental Multi-Cap Core Portfolio (Series ID: S000053788)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class A    | MFNAX         | C000169216 |
| Class C    | MFNCX         | C000169217 |
| Class IS   | MFNSX         | C000169218 |
| Class I    | MFNIX         | C000169219 |

---

### US Core Portfolio (Series ID: S000053789)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MUOIX         | C000169220 |
| Class A    | MUOAX         | C000169221 |
| Class C    | MUOCX         | C000169222 |
| Class IS   | MUOSX         | C000169223 |
| Class T    | nan           | C000178596 |

---

### Emerging Markets Breakout Nations Portfolio (Series ID: S000055820)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | EMIPX         | C000175773 |
| Class A    | EMAPX         | C000175774 |
| Class C    | EMCPX         | C000175775 |
| Class IS   | EMSPX         | C000175776 |
| Class T    | nan           | C000178597 |

---

### Counterpoint Global Portfolio (Series ID: S000059877)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| A          | GLCAX         | C000195878 |
| C          | GLCDX         | C000195879 |
| I          | GLCIX         | C000195880 |
| IS         | GLCSX         | C000195881 |

---

### Global Concentrated Real Estate Portfolio (Series ID: S000061990)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MCQIX         | C000200795 |
| Class A    | MCQAX         | C000200796 |
| Class C    | MCQCX         | C000200797 |
| Class IS   | MCQJX         | C000200798 |

---

### Multi-Asset Real Return Portfolio (Series ID: S000061991)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MRJIX         | C000200799 |
| Class A    | MRJAX         | C000200800 |
| Class C    | MRJCX         | C000200801 |
| Class IS   | MRJSX         | C000200802 |

---

### Global Endurance Portfolio (Series ID: S000063049)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class IS   | MSJSX         | C000204517 |
| Class A    | MSJAX         | C000204518 |
| Class C    | MSJCX         | C000204519 |
| Class I    | MSJIX         | C000204520 |

---

### Global Permanence Portfolio (Series ID: S000065236)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class IS   | MGKQX         | C000211165 |
| Class A    | MGKAX         | C000211166 |
| Class C    | MGKCX         | C000211167 |
| Class I    | MGKIX         | C000211168 |

---

### China Equity Portfolio (Series ID: S000066376)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class IS   | MAKSX         | C000214194 |
| Class A    | MAKAX         | C000214195 |
| Class C    | MAKCX         | C000214196 |
| Class I    | MAKIX         | C000214197 |

---

### Developing Opportunity Portfolio (Series ID: S000067259)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class I    | C000216354 |
| Class A    | C000216355 |
| Class IS   | C000216356 |
| Class C    | C000216357 |

---

### Permanence Portfolio (Series ID: S000068163)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class IS   | MSHPX         | C000218314 |
| Class A    | MSHNX         | C000218315 |
| Class C    | MSHOX         | C000218316 |
| Class I    | MSHMX         | C000218317 |

---

### Global Focus Real Estate Portfolio (Series ID: S000072500)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class IS   | C000228806 |
| Class A    | C000228807 |
| Class C    | C000228808 |
| Class I    | C000228809 |

---

### U.S. Focus Real Estate Portfolio (Series ID: S000073484)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class IS   | C000230424 |
| Class A    | C000230425 |
| Class C    | C000230426 |
| Class I    | C000230427 |

---

### Vitality Portfolio (Series ID: S000074797)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class I    | C000233002 |
| Class A    | C000233003 |
| Class C    | C000233004 |
| Class IS   | C000233005 |

---

### Sustainable Emerging Markets Portfolio (Series ID: S000076838)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class R6   | MSDMX         | C000236911 |
| Class A    | MSDQX         | C000236912 |
| Class C    | MSDOX         | C000236913 |
| Class I    | MSDUX         | C000236914 |

---

### American Resilience Portfolio (Series ID: S000076841)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class C    | MSBWX         | C000236923 |
| Class I    | MSBVX         | C000236924 |
| Class R6   | MSBQX         | C000236925 |
| Class A    | MSCUX         | C000236926 |

---

### International Resilience Portfolio (Series ID: S000076842)

---

|  |  |  |
|:---|:---|:---|
| Class Name | Ticker Symbol | Class ID   |
| Class I    | MSDKX         | C000236927 |
| Class C    | MSDEX         | C000236928 |
| Class R6   | MSCZX         | C000236929 |
| Class A    | MSDFX         | C000236930 |

---

## Series and Classes Contracts Data

### ACTIVE INTERNATIONAL ALLOCATION PORTFOLIO (Series ID: S000002820)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007736 | CLASS I      | MSACX           |
| C000007737 | CLASS A      | MSIBX           |
| C000113799 | Class L      | MSLLX           |
| C000155887 | Class C      | MSAAX           |
| C000178569 | Class T      |  |
| C000215548 | Class IS     | MAIJX           |
| C000215549 | Class IR     | MAIHX           |

### U.S. REAL ESTATE PORTFOLIO (Series ID: S000002821)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007738 | CLASS I      | MSUSX           |
| C000007739 | CLASS A      | MUSDX           |
| C000104301 | Class L      | MSULX           |
| C000126911 | Class IS     | MURSX           |
| C000155888 | Class C      | MSURX           |
| C000178570 | Class T      |  |
| C000198814 | Class IR     | MRETX           |

### Inception Portfolio (Series ID: S000002825)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007744 | CLASS I      | MSSGX           |
| C000007745 | CLASS A      | MSSMX           |
| C000104303 | Class L      | MSSLX           |
| C000129402 | Class IS     | MFLLX           |
| C000155889 | Class C      | MSCOX           |
| C000178571 | Class T      |  |

### EMERGING MARKETS PORTFOLIO (Series ID: S000002826)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007746 | CLASS I      | MGEMX           |
| C000007747 | CLASS A      | MMKBX           |
| C000113803 | Class L      | MSELX           |
| C000126912 | Class IS     | MMMPX           |
| C000155890 | Class C      | MSEPX           |
| C000178572 | Class T      |  |
| C000198815 | Class IR     | MRGEX           |

### GROWTH PORTFOLIO (Series ID: S000002828)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007750 | CLASS I      | MSEQX           |
| C000007751 | CLASS A      | MSEGX           |
| C000113805 | Class L      | MSHLX           |
| C000126914 | Class IS     | MGRPX           |
| C000155892 | Class C      | MSGUX           |
| C000178573 | Class T      |  |
| C000198816 | Class IR     | MGHRX           |

### GLOBAL FRANCHISE PORTFOLIO (Series ID: S000002830)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007754 | CLASS I      | MSFAX           |
| C000007755 | CLASS A      | MSFBX           |
| C000113809 | Class L      | MSFLX           |
| C000155893 | Class C      | MSGFX           |
| C000156276 | Class IS     | MGISX           |
| C000178574 | Class T      |  |

### INTERNATIONAL EQUITY PORTFOLIO (Series ID: S000002832)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007758 | CLASS I      | MSIQX           |
| C000007759 | CLASS A      | MIQBX           |
| C000113811 | Class L      | MSQLX           |
| C000126915 | Class IS     | MIQPX           |
| C000155894 | Class C      | MSECX           |
| C000178575 | Class T      |  |

### INTERNATIONAL REAL ESTATE PORTFOLIO (Series ID: S000002835)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000007763 | CLASS I      | MSUAX           |
| C000007764 | CLASS A      | IERBX           |
| C000113813 | Class L      | MSOLX           |
| C000126916 | Class IS     | MIREX           |
| C000155895 | Class C      | MSIJX           |
| C000178576 | Class T      |  |

### Global Real Estate Portfolio (Series ID: S000012825)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000034677 | Class I      | MRLAX           |
| C000034678 | Class A      | MRLBX           |
| C000065130 | Class L      | MGRLX           |
| C000126917 | Class IS     | MGREX           |
| C000155896 | Class C      | MSRDX           |
| C000178577 | Class T      |  |
| C000198819 | Class IR     | MRLEX           |

### International Opportunity Portfolio (Series ID: S000027992)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000085087 | Class I      | MIOIX           |
| C000085088 | Class L      | MIOLX           |
| C000085089 | Class A      | MIOPX           |
| C000126918 | Class IS     | MNOPX           |
| C000155897 | Class C      | MSOCX           |
| C000178578 | Class T      |  |
| C000198820 | Class IR     | MRNPX           |

### Advantage Portfolio (Series ID: S000027993)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000085091 | Class I      | MPAIX           |
| C000085092 | Class L      | MAPLX           |
| C000085093 | Class A      | MAPPX           |
| C000126919 | Class IS     | MADSX           |
| C000155898 | Class C      | MSPRX           |
| C000178579 | Class T      |  |

### Global Opportunity Portfolio (Series ID: S000027995)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000085098 | Class I      | MGGIX           |
| C000085099 | Class L      | MGGLX           |
| C000085100 | Class A      | MGGPX           |
| C000126921 | Class IS     | MGTSX           |
| C000155900 | Class C      | MSOPX           |
| C000178580 | Class T      |  |
| C000198822 | Class IR     | MGORX           |

### Global Infrastructure Portfolio (Series ID: S000029874)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000091816 | CLASS I      | MTIIX           |
| C000091817 | CLASS L      | MTILX           |
| C000091818 | CLASS A      | MTIPX           |
| C000126922 | Class IS     | MSGPX           |
| C000155901 | Class C      | MSGTX           |
| C000178581 | Class T      |  |
| C000198823 | Class IR     | MRGOX           |

### Global Insight Portfolio (Series ID: S000030616)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000094891 | Class I      | MIGIX           |
| C000094892 | Class L      | MIGLX           |
| C000094893 | Class A      | MIGPX           |
| C000155902 | Class C      | MSPTX           |
| C000178582 | Class T      |  |
| C000228507 | Class IS     |  |

### Global Discovery Portfolio (Series ID: S000030617)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000094895 | Class I      | MLDIX           |
| C000094896 | Class L      | MGDLX           |
| C000094897 | Class A      | MGDPX           |
| C000155903 | Class C      | MSPCX           |
| C000178583 | Class T      |  |
| C000198824 | Class IS     |  |
| C000198825 | Class IR     |  |

### International Advantage Portfolio (Series ID: S000030618)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000094898 | Class I      | MFAIX           |
| C000094899 | Class L      | MSALX           |
| C000094900 | Class A      | MFAPX           |
| C000155904 | Class C      | MSIAX           |
| C000178584 | Class T      |  |
| C000198826 | Class IS     | IDVSX           |

### Asian Equity Portfolio (Series ID: S000030707)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000095149 | Class I      |  |
| C000095150 | Class L      |  |
| C000095151 | Class A      |  |
| C000155905 | Class C      |  |

### Insight Portfolio (Series ID: S000035027)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000107706 | Class I      | MFPIX           |
| C000107707 | Class A      | MFPHX           |
| C000107708 | Class L      | MFPLX           |
| C000155906 | Class C      | MSSPX           |
| C000178585 | Class T      |  |
| C000198827 | Class IS     |  |

### Emerging Markets Fixed Income Opportunities Portfolio (Series ID: S000037168)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000114463 | Class I      | MEAIX           |
| C000114464 | Class A      | MEAPX           |
| C000114466 | Class L      | MEALX           |
| C000126923 | Class IS     | MRDPX           |
| C000155908 | Class C      | MSEDX           |
| C000178587 | Class T      |  |

### Multi-Asset Portfolio (Series ID: S000037170)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000114471 | Class A      | MMPPX           |
| C000114473 | Class L      | MMPLX           |
| C000114474 | Class I      | MMPIX           |
| C000155909 | Class C      | MSMEX           |
| C000156277 | Class IS     | MSPMX           |
| C000178588 | Class T      |  |

### Next Gen Emerging Markets Portfolio (Series ID: S000037507)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000115785 | Class I      | MFMIX           |
| C000115786 | Class A      | MFMPX           |
| C000115788 | Class L      | MFMLX           |
| C000152578 | Class IS     | MSRFX           |
| C000155910 | Class C      | MSFEX           |
| C000178589 | Class T      |  |

### Global Sustain Portfolio (Series ID: S000041864)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000129960 | Class I      | MGQIX           |
| C000129961 | Class A      | MGQAX           |
| C000129962 | Class L      | MGQLX           |
| C000129963 | Class IS     | MGQSX           |
| C000155911 | Class C      | MSGQX           |
| C000178590 | Class T      |  |

### Emerging Markets Leaders Portfolio (Series ID: S000047473)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000149047 | Class I      | MELIX           |
| C000149048 | Class A      | MELAX           |
| C000149049 | Class L      |  |
| C000149050 | Class IS     | MELSX           |
| C000155912 | Class C      | MEMLX           |
| C000178591 | Class T      |  |
| C000226932 | Class IR     |  |

### Emerging Markets Small Cap Portfolio (Series ID: S000051831)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000163116 | Class I      | MSEMX           |
| C000163117 | Class A      | MSEOX           |
| C000163118 | Class C      | MSESX           |
| C000163119 | Class IS     | MSETX           |
| C000178592 | Class T      |  |

### Asia Opportunity Portfolio (Series ID: S000051832)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000163120 | Class I      | MSAQX           |
| C000163121 | Class A      | MSAUX           |
| C000163122 | Class C      | MSAWX           |
| C000163123 | Class IS     | MSAYX           |
| C000178593 | Class T      |  |

### Global Concentrated Portfolio (Series ID: S000053786)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000169208 | Class I      | MLNIX           |
| C000169209 | Class A      | MLNAX           |
| C000169210 | Class C      | MLNCX           |
| C000169211 | Class IS     | MLNSX           |
| C000178594 | Class T      |  |

### Global Core Portfolio (Series ID: S000053787)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000169212 | Class I      | MLMIX           |
| C000169213 | Class A      | MLMAX           |
| C000169214 | Class C      | MLMCX           |
| C000169215 | Class IS     | MLMSX           |
| C000178595 | Class T      |  |

### Fundamental Multi-Cap Core Portfolio (Series ID: S000053788)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000169216 | Class A      | MFNAX           |
| C000169217 | Class C      | MFNCX           |
| C000169218 | Class IS     | MFNSX           |
| C000169219 | Class I      | MFNIX           |

### US Core Portfolio (Series ID: S000053789)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000169220 | Class I      | MUOIX           |
| C000169221 | Class A      | MUOAX           |
| C000169222 | Class C      | MUOCX           |
| C000169223 | Class IS     | MUOSX           |
| C000178596 | Class T      |  |

### Emerging Markets Breakout Nations Portfolio (Series ID: S000055820)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000175773 | Class I      | EMIPX           |
| C000175774 | Class A      | EMAPX           |
| C000175775 | Class C      | EMCPX           |
| C000175776 | Class IS     | EMSPX           |
| C000178597 | Class T      |  |

### Counterpoint Global Portfolio (Series ID: S000059877)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000195878 | A            | GLCAX           |
| C000195879 | C            | GLCDX           |
| C000195880 | I            | GLCIX           |
| C000195881 | IS           | GLCSX           |

### Global Concentrated Real Estate Portfolio (Series ID: S000061990)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000200795 | Class I      | MCQIX           |
| C000200796 | Class A      | MCQAX           |
| C000200797 | Class C      | MCQCX           |
| C000200798 | Class IS     | MCQJX           |

### Multi-Asset Real Return Portfolio (Series ID: S000061991)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000200799 | Class I      | MRJIX           |
| C000200800 | Class A      | MRJAX           |
| C000200801 | Class C      | MRJCX           |
| C000200802 | Class IS     | MRJSX           |

### Global Endurance Portfolio (Series ID: S000063049)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000204517 | Class IS     | MSJSX           |
| C000204518 | Class A      | MSJAX           |
| C000204519 | Class C      | MSJCX           |
| C000204520 | Class I      | MSJIX           |

### Global Permanence Portfolio (Series ID: S000065236)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000211165 | Class IS     | MGKQX           |
| C000211166 | Class A      | MGKAX           |
| C000211167 | Class C      | MGKCX           |
| C000211168 | Class I      | MGKIX           |

### China Equity Portfolio (Series ID: S000066376)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000214194 | Class IS     | MAKSX           |
| C000214195 | Class A      | MAKAX           |
| C000214196 | Class C      | MAKCX           |
| C000214197 | Class I      | MAKIX           |

### Developing Opportunity Portfolio (Series ID: S000067259)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216354 | Class I      |  |
| C000216355 | Class A      |  |
| C000216356 | Class IS     |  |
| C000216357 | Class C      |  |

### Permanence Portfolio (Series ID: S000068163)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000218314 | Class IS     | MSHPX           |
| C000218315 | Class A      | MSHNX           |
| C000218316 | Class C      | MSHOX           |
| C000218317 | Class I      | MSHMX           |

### Global Focus Real Estate Portfolio (Series ID: S000072500)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000228806 | Class IS     |  |
| C000228807 | Class A      |  |
| C000228808 | Class C      |  |
| C000228809 | Class I      |  |

### U.S. Focus Real Estate Portfolio (Series ID: S000073484)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000230424 | Class IS     |  |
| C000230425 | Class A      |  |
| C000230426 | Class C      |  |
| C000230427 | Class I      |  |

### Vitality Portfolio (Series ID: S000074797)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000233002 | Class I      |  |
| C000233003 | Class A      |  |
| C000233004 | Class C      |  |
| C000233005 | Class IS     |  |

### Sustainable Emerging Markets Portfolio (Series ID: S000076838)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000236911 | Class R6     | MSDMX           |
| C000236912 | Class A      | MSDQX           |
| C000236913 | Class C      | MSDOX           |
| C000236914 | Class I      | MSDUX           |

### American Resilience Portfolio (Series ID: S000076841)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000236923 | Class C      | MSBWX           |
| C000236924 | Class I      | MSBVX           |
| C000236925 | Class R6     | MSBQX           |
| C000236926 | Class A      | MSCUX           |

### International Resilience Portfolio (Series ID: S000076842)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000236927 | Class I      | MSDKX           |
| C000236928 | Class C      | MSDEX           |
| C000236929 | Class R6     | MSCZX           |
| C000236930 | Class A      | MSDFX           |

## FORM 24F-2NT: Annual Notice of Securities Sold Pursuant to Rule 24f-2

### 24F-2NT: Filer Information

**Filer CIK:** 0000836487

**Is this a LIVE or TEST Filing?:** LIVE

**Filer Investment Company Type:** N-1A

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** Morgan Stanley Institutional Funds, Inc.

- **Address:** 522 Fifth Avenue, New York, NY 10036

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-5624

   **Securities Act File Number:** 033-23166

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2022

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $10565871750.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $17619008326.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $17619008326.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-7053136576.00

- **(vii) Multiplier for determining registration fee:** 0.0001102

- **(viii) Registration fee due:** $0.00

- **8. Total of the amount of the registration fee due plus any interest due:** $0.00

**Signatures**

**Name and Title:** Treasurer

**Date:** 03/31/2023

**Signature:** Frank Smith