# EDGAR Filing Document

**Accession Number:** 0000320351
**File Stem:** 0000035402-25-001457
**Filing Date:** 2025-10
**Character Count:** 47744
**Document Hash:** af5857473b573da6eaf0bcd0ff135104
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000035402-25-001457.hdr.sgml**: 20251028

**ACCESSION NUMBER**: 0000035402-25-001457

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250831

**FILED AS OF DATE**: 20251028

**DATE AS OF CHANGE**: 20251028

**PERIOD START**: 20260228

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIDELITY SELECT PORTFOLIOS
- **CENTRAL INDEX KEY:** 0000320351

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MA
- **FISCAL YEAR END:** 0228

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-03114
- **FILM NUMBER:** 251424515

**BUSINESS ADDRESS:**
- **STREET 1:** 245 SUMMER STREET
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02210
- **BUSINESS PHONE:** 617-563-7000

**MAIL ADDRESS:**
- **STREET 1:** 245 SUMMER STREET
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02210

## Series and Classes Contracts Data

### Health Care Portfolio (Series ID: S000007466)

| Class ID   | Class Name            | Ticker Symbol   |
|:---|:---|:---|
| C000020440 | Health Care Portfolio | FSPHX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** Fidelity Select Portfolios

- **b. Investment Company Act file number:** 811-03114

- **c. CIK number of Registrant:** 0000320351

- **d. LEI of Registrant:** Z57125JG1LHEQKDYS630

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 245 Summer Street

  - **City:** Boston

  - **State:** MA

  - **Foreign country:** US

  - **Zip / Postal Code:** 02210

  - **Telephone number:** 1-800-FIDELITY

**Item A.2. Information about the Series.**

- **a. Name of Series:** Select Health Care Portfolio

- **b. EDGAR series identifier (if any):** S000007466

- **c. LEI of Series:** I3SBCDEPIC5NBQILUV22

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-02-28

- **b. Date as of which information is reported:** 2025-08-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $5996521109.27

**Total Liabilities:** $114628374.25

**Net Assets:** $5881892735.02

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000020440 | 2.68%                | -0.86%               | 4.44%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $2879959.27              | $151044745.31                              |
| Month 2  | $54285943.96             | $-104942016.50                             |
| Month 3  | $70818528.36             | $182977995.69                              |

### Schedule of Portfolio Investments

| Name                             | Title                                                  | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| SURGERY PARTNERS INC             | SURGERY PARTNERS INC                                   | CUSIP: 86881A100<br>LEI: 549300LC82HG33S19I03 | Long             | EC               | CORP              | US        |   1800000 | NS      | $40842000.00  | 0.69%             |  |  |  | No            |                  1 | On Loan: —       |
| INSIGHTEC LTD                    | INSIGHTEC LTD SER G PC PP                              | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | IL        |  11853768 | NS      | $8771788.32   | 0.15%             |  |  |  | Yes           |                  3 | On Loan: No      |
| UPSTREAM BIO INC                 | UPSTREAM BIO INC                                       | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1080000 | NS      | $18500400.00  | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| THERMO FISHER SCIENTIFIC INC     | THERMO FISHER SCIENTIFIC INC                           | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |    145000 | NS      | $71444400.00  | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| PENUMBRA INC                     | PENUMBRA INC                                           | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |   1054000 | NS      | $287362560.00 | 4.89%             |  |  |  | No            |                  1 | On Loan: No      |
| SHOULDER INNOVATIONS INC         | SHOULDER INNOVATIONS INC                               | CUSIP: 82537J108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96700 | NS      | $1433094.00   | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA HOLDINGS INC               | IQVIA HOLDINGS INC                                     | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |    375000 | NS      | $71553750.00  | 1.22%             |  |  |  | No            |                  1 | On Loan: No      |
| ABBVIE INC                       | ABBVIE INC                                             | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |    640000 | NS      | $134656000.00 | 2.29%             |  |  |  | No            |                  1 | On Loan: No      |
| KARDIUM INC/US                   | KARDIUM INC US SRE D-7 PC PP (2ND CLOSING JUNE 2025)   | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   3477566 | NS      | $1982212.62   | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GALVANIZE THERAPEUTICS           | GALVANIZE THERAPEUTICS CONV 10% 02/28/2027 P/P         | CUSIP: N/A<br>LEI: N/A                        | Long             | DBT              | CORP              | US        |   1748893 | PA      | $2234560.11   | 0.04%             | 2027-02-28      | Fixed         | 0.10%                 | Yes           |                  3 | On Loan: No      |
| PRIVIA HEALTH GROUP INC          | PRIVIA HEALTH GROUP INC                                | CUSIP: 74276R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   2800000 | NS      | $64512000.00  | 1.10%             |  |  |  | No            |                  1 | On Loan: No      |
| CENTESSA PHARMACEUTICALS PLC     | CENTESSA PHARMACEUTICALS LTD ADR                       | CUSIP: 152309100<br>LEI: 213800GIDAARDSKOI827 | Long             | EC               | CORP              | GB        |    280000 | NS      | $4701200.00   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| STRYKER CORP                     | STRYKER CORP                                           | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |    400000 | NS      | $156564000.00 | 2.66%             |  |  |  | No            |                  1 | On Loan: No      |
| CRINETICS PHARMACEUTICALS INC    | CRINETICS PHARMACEUTICALS INC                          | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |   1290000 | NS      | $39977100.00  | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| GALVANIZE THERAPEUTICS           | GALVANIZE THERAPEUTICS SER C-1 PC PERP PP              | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   5823768 | NS      | $2562457.92   | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PHREESIA INC                     | PHREESIA INC                                           | CUSIP: 71944F106<br>LEI: 5493000HHF8NU4QOCG53 | Long             | EC               | CORP              | US        |   1000000 | NS      | $31660000.00  | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMUNOCORE HOLDINGS PLC          | IMMUNOCORE HOLDINGS LTD ADR                            | CUSIP: 45258D105<br>LEI: 213800IUE3DFS84BVN18 | Long             | EC               | CORP              | GB        |    520000 | NS      | $16754400.00  | 0.28%             |  |  |  | No            |                  1 | On Loan: —       |
| KESTRA MEDICAL TECHNOLOGIES INC  | KESTRA MEDICAL TECHNOLOGIES INC                        | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |    638900 | NS      | $10311846.00  | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| NEWAMSTERDAM PHARMA COMPANY NV   | NEWAMSTERDAM PHARMA COMPANY NV                         | CUSIP: N/A<br>LEI: 984500B6549TF6E14D36       | Long             | EC               | CORP              | NL        |    280000 | NS      | $6734000.00   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| ENDEAVOR BIOMEDICINES INC        | ENDEAVOR BIOMEDICINES INC SERIES C PC PP               | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1366212 | NS      | $7131626.64   | 0.12%             |  |  |  | Yes           |                  3 | On Loan: No      |
| DISC MEDICINE INC                | DISC MEDICINE INC                                      | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    600000 | NS      | $35787000.00  | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| ASIMOV INC                       | ASIMOV INC SER B PC PP                                 | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    101438 | NS      | $2714480.88   | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| WUGEN INC                        | WUGEN INC SER B PC PP                                  | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    454342 | NS      | $699686.68    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| MOONLAKE IMMUNOTHERAPEUTICS      | MOONLAKE IMMUNOTHERAPEUTICS                            | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |    460000 | NS      | $25645000.00  | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| ORUKA THERAPEUTICS INC           | ORUKA THERAPEUTICS INC                                 | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |    999710 | NS      | $14795708.00  | 0.25%             |  |  |  | No            |                  1 | On Loan: —       |
| MANUS BIO INC                    | MANUS BIO INC SER ONE-6 PC PP                          | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1079396 | NS      | $3583594.72   | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CIGNA GROUP (THE)                | CIGNA GROUP (THE)                                      | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |     69000 | NS      | $20760030.00  | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| SCHOLAR ROCK HOLDING CORP        | SCHOLAR ROCK HOLDING CORP                              | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |     97528 | NS      | $3184289.20   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| LIFESTANCE HEALTH GROUP INC      | LIFESTANCE HEALTH GROUP INC                            | CUSIP: 53228F101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   3600000 | NS      | $19728000.00  | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X GENOMICS INC                 | 10X GENOMICS INC                                       | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |   2080000 | NS      | $29140800.00  | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| NURIX THERAPEUTICS INC           | NURIX THERAPEUTICS INC                                 | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1690000 | NS      | $15784600.00  | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| DMED BIOPHARMACEUTICAL CO LTD    | DMED BIOPHARMACEUTICAL CO LTD SER C PC PP              | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | CN        |    330316 | NS      | $2513704.76   | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ARGENX SE                        | ARGENX SE SPONSORED ADR                                | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |    280000 | NS      | $199416000.00 | 3.39%             |  |  |  | No            |                  1 | On Loan: —       |
| ROYALTY PHARMA PLC               | ROYALTY PHARMA PLC                                     | CUSIP: N/A<br>LEI: 549300FGFN7VOK8BZR03       | Long             | EC               | CORP              | GB        |   1750000 | NS      | $62965000.00  | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| ALEDADE INC                      | ALEDADE INC SER B1 PC PP                               | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    201220 | NS      | $7358615.40   | 0.13%             |  |  |  | Yes           |                  3 | On Loan: No      |
| KARDIUM INC/US                   | KARDIUM INC US CONV 10% 12/31/2026 PP                  | CUSIP: N/A<br>LEI: N/A                        | Long             | DBT              | CORP              | US        |   3839963 | PA      | $4526163.85   | 0.08%             | 2026-12-31      | Fixed         | 0.10%                 | Yes           |                  3 | On Loan: No      |
| ULTRAGENYX PHARMACEUTICAL INC    | ULTRAGENYX PHARMA INC                                  | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |    450000 | NS      | $13482000.00  | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| CARTESIAN THERAPEUTICS INC       | CARTESIAN THERAPEUTICS INC                             | CUSIP: 816212302<br>LEI: 529900NMN0LACZOL7C43 | Long             | EC               | CORP              | US        |    368992 | NS      | $3708369.60   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| GALVANIZE THERAPEUTICS           | GALVANIZE THERAPEUTICS SER B PC PERP PP                | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   3696429 | NS      | $2661428.88   | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PERSPECTIVE THERAPEUTICS INC     | PERSPECTIVE THERAPEUTICS INC                           | CUSIP: 46489V302<br>LEI: 5493005LRKM6BCABC605 | Long             | EC               | CORP              | US        |    600000 | NS      | $2016000.00   | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| KARDIUM INC/US                   | KARDIUM INC US SRE D-7 PC PP (1ST CLOSING JUNE 2025)   | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    723517 | NS      | $419639.86    | 0.01%             |  |  |  | No            |                  3 | On Loan: No      |
| SALUDA MEDICAL INC               | SALUDA MEDICAL INC SER E PC PP                         | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    759659 | NS      | $3046232.59   | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AVIDITY BIOSCIENCES INC          | AVIDITY BIOSCIENCES                                    | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    670000 | NS      | $31208600.00  | 0.53%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BIOROBOTICS CORP         | PROCEPT BIOROBOTICS CORP                               | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    690000 | NS      | $27717300.00  | 0.47%             |  |  |  | No            |                  1 | On Loan: —       |
| BIONTECH SE                      | BIONTECH SE ADR                                        | CUSIP: 09075V102<br>LEI: 894500UZJ5LG1F8J1U58 | Long             | EC               | CORP              | DE        |    400000 | NS      | $40000000.00  | 0.68%             |  |  |  | No            |                  1 | On Loan: —       |
| MEDICAL MICROINSTRUMENTS INC     | MEDICAL MICROINSTRUMENTS INC SER C PC PP               | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    316310 | NS      | $10656483.90  | 0.18%             |  |  |  | Yes           |                  3 | On Loan: No      |
| JANUX THERAPEUTICS INC           | JANUX THERAPEUTICS INC                                 | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    846163 | NS      | $19224823.36  | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| EVOLENT HEALTH INC               | EVOLENT HEALTH INC A                                   | CUSIP: 30050B101<br>LEI: 549300CZOCFHQ2BBTR11 | Long             | EC               | CORP              | US        |   1980959 | NS      | $19116254.35  | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| ENLIVEN THERAPEUTICS INC         | ENLIVEN THERAPEUTICS INC                               | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1220000 | NS      | $24729400.00  | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| WAYSTAR HOLDING CORP             | WAYSTAR HOLDING CORP                                   | CUSIP: 946784105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    640000 | NS      | $24243200.00  | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| VERACYTE INC                     | VERACYTE INC                                           | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |   1400000 | NS      | $42476000.00  | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION MEDICINES INC         | REVOLUTION MEDICINES INC                               | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |    630000 | NS      | $23921100.00  | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| OMADA HEALTH INC                 | OMADA HEALTH INC (180 DAY LOCK-UP)                     | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |    717691 | NS      | $17002099.79  | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| ELEMENT BIOSCIENCES INC          | ELEMENT BIOSCIENCES INC SER C PC PP                    | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    572265 | NS      | $4360659.30   | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| SHOULDER INNOVATIONS INC         | SHOULDER INNOVATIONS INC(180 Day Lockup)               | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |    448586 | NS      | $6648044.52   | 0.11%             |  |  |  | Yes           |                  1 | On Loan: No      |
| ELEMENT BIOSCIENCES INC          | ELEMENT BIOSCIENCES INC SER D1 PC PP                   | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    413355 | NS      | $2232117.00   | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| VAXCYTE INC                      | VAXCYTE INC                                            | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |   1200000 | NS      | $36948000.00  | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| HEARTFLOW INC                    | HEARTFLOW INC (180 DAY LOCK-UP)                        | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |    636013 | NS      | $20034409.50  | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| VIRIDIAN THERAPEUTICS INC        | VIRIDIAN THERAPEUTICS INC                              | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |   2703616 | NS      | $49692462.08  | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| SOLENO THERAPEUTICS INC          | SOLENO THERAPEUTICS INC                                | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |    810000 | NS      | $54812700.00  | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| SPYRE THERAPEUTICS INC           | SPYRE THERAPEUTICS INC                                 | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |    650000 | NS      | $10718500.00  | 0.18%             |  |  |  | No            |                  1 | On Loan: —       |
| OUTSET MEDICAL INC               | OUTSET MEDICAL INC                                     | CUSIP: 690145206<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1345000 | NS      | $18708950.00  | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| REZOLUTE INC                     | REZOLUTE INC                                           | CUSIP: 76200L309<br>LEI: 549300T05L48T72P2G08 | Long             | EC               | CORP              | US        |   2800000 | NS      | $19936000.00  | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| BOSTON SCIENTIFIC CORP           | BOSTON SCIENTIFIC CORP                                 | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |   4180000 | NS      | $440990000.00 | 7.50%             |  |  |  | No            |                  1 | On Loan: No      |
| ELI LILLY and CO                 | ELI LILLY and CO                                       | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |    400000 | NS      | $293032000.00 | 4.98%             |  |  |  | No            |                  1 | On Loan: No      |
| ALEDADE INC                      | ALEDADE INC SER E1 PC PP                               | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |     56664 | NS      | $2072202.48   | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| STRUCTURE THERAPEUTICS INC       | STRUCTURE THERAPEUTICS INC ADR                         | CUSIP: 86366E106<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |    850000 | NS      | $16405000.00  | 0.28%             |  |  |  | No            |                  1 | On Loan: No      |
| SUMMIT THERAPEUTICS INC          | SUMMIT THERAPEUTICS INC                                | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    570000 | NS      | $13509000.00  | 0.23%             |  |  |  | No            |                  1 | On Loan: —       |
| OMADA HEALTH INC                 | OMADA HEALTH INC                                       | CUSIP: 68170A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     80000 | NS      | $1895200.00   | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ANNEXON INC                      | ANNEXON INC                                            | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1200000 | NS      | $2472000.00   | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X GENOMICS INC                 | 10X GENOMICS INC CL B 144A                             | CUSIP: N/A<br>LEI: 5493003Z6741WNLG7H43       | Long             | EC               | CORP              | US        |    500000 | NS      | $7005000.00   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| JADE BIOSCIENCES INC             | JADE BIOSCIENCES INC                                   | CUSIP: 008064206<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    400000 | NS      | $3160000.00   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| INTUITIVE SURGICAL INC           | INTUITIVE SURGICAL INC                                 | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |    100000 | NS      | $47329500.00  | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| SALUDA MEDICAL INC               | SALUDA MEDICAL INC SER E-1 PC PP                       | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    395700 | NS      | $3066675.00   | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AGILON HEALTH INC                | AGILON HEALTH INC                                      | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |  12000000 | NS      | $15360000.00  | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| CYTOKINETICS INC                 | CYTOKINETICS INC                                       | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |    850000 | NS      | $30030500.00  | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| CARIS LIFE SCIENCES INC          | CARIS LIFE SCIENCES INC (180 DAY LOCK-UP)              | CUSIP: N/A<br>LEI: 549300LX5LO78M5VPY43       | Long             | EC               | CORP              | US        |   1729127 | NS      | $66381185.53  | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Fidelity Revere Street Trust     | Fidelity Cash Central Fund                             | CUSIP: 31635A105<br>LEI: 549300BDV45LJNXBZC55 | Long             | STIV             | RF                | US        |  13179360 | NS      | $13181995.61  | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| AKERO THERAPEUTICS INC           | AKERO THERAPEUTICS INC                                 | CUSIP: 00973Y108<br>LEI: 549300SI3KG74LBE2955 | Long             | EC               | CORP              | US        |    420000 | NS      | $19626600.00  | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| WAVE LIFE SCIENCES LTD           | WAVE LIFE SCIENCES LTD                                 | CUSIP: N/A<br>LEI: 54930070006GPKFYZ813       | Long             | EC               | CORP              | SG        |   1184796 | NS      | $11374041.60  | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| ASCENDIS PHARMA A/S              | ASCENDIS PHARMA AS SPON ADR                            | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |    740000 | NS      | $143759800.00 | 2.44%             |  |  |  | No            |                  1 | On Loan: No      |
| EDWARDS LIFESCIENCES CORP        | EDWARDS LIFESCIENCES CORP                              | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |   1500000 | NS      | $122010000.00 | 2.07%             |  |  |  | No            |                  1 | On Loan: No      |
| LEGEND BIOTECH CORP              | LEGEND BIOTECH CORP SPON ADR                           | CUSIP: 52490G102<br>LEI: 254900EIUFZTW136H859 | Long             | EC               | CORP              | KY        |   3670000 | NS      | $127459100.00 | 2.17%             |  |  |  | No            |                  1 | On Loan: No      |
| ASTRANA HEALTH INC               | ASTRANA HEALTH INC                                     | CUSIP: 03763A207<br>LEI: 5493008O4R82Q4STJ936 | Long             | EC               | CORP              | US        |    620800 | NS      | $19840768.00  | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| CLEERLY INC                      | CLEERLY INC SER C PC PP                                | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   1285367 | NS      | $14537500.77  | 0.25%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ELEMENT BIOSCIENCES INC          | ELEMENT BIOSCIENCES INC SER D PC PP                    | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    413355 | NS      | $2232117.00   | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| HEAL THRIVE HOLDINGS LLC         | HEAL THRIVE HOLDINGS LLC PP                            | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |    473270 | NS      | $1381948.40   | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| METSERA INC                      | METSERA INC                                            | CUSIP: 59267L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    305342 | NS      | $10775519.18  | 0.18%             |  |  |  | No            |                  1 | On Loan: —       |
| SARTORIUS STEDIM BIOTECH         | SARTORIUS STEDIM BIOTECH                               | CUSIP: N/A<br>LEI: 52990006IVXY7GCSSR39       | Long             | EC               | CORP              | FR        |    128000 | NS      | $26190785.35  | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| SALUDA MEDICAL INC               | SALUDA MEDICAL INC CONV 0% PERP P/P                    | CUSIP: N/A<br>LEI: N/A                        | Long             | DBT              | CORP              | US        |   3194800 | PA      | $3696064.12   | 0.06%             | 2199-12-31      | Fixed         | 0.00%                 | Yes           |                  3 | On Loan: No      |
| DANAHER CORP                     | DANAHER CORP                                           | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |   1710000 | NS      | $351952200.00 | 5.98%             |  |  |  | No            |                  1 | On Loan: No      |
| ACUMEN PHARMACEUTICALS INC       | ACUMEN PHARMACEUTICALS INC                             | CUSIP: 00509G209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1140000 | NS      | $1550400.00   | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| PHARVARIS BV                     | PHARVARIS BV                                           | CUSIP: N/A<br>LEI: 9845003BE146D3B75D32       | Long             | EC               | CORP              | NL        |    800000 | NS      | $17320000.00  | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| CANDID THERAPEUTICS              | CANDID THERAPEUTICS INC SER B PC PP                    | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |   3162302 | NS      | $3130678.98   | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| EXACT SCIENCES CORP              | EXACT SCIENCES CORP                                    | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |   2500000 | NS      | $118550000.00 | 2.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ARCELLX INC                      | ARCELLX INC                                            | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    430000 | NS      | $29837700.00  | 0.51%             |  |  |  | No            |                  1 | On Loan: —       |
| STOKE THERAPEUTICS INC           | STOKE THERAPEUTICS INC                                 | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |   1200000 | NS      | $23712000.00  | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| DAY ONE BIOPHARMACEUTICALS INC   | DAY ONE BIOPHARMACEUTICALS INC                         | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1000000 | NS      | $7510000.00   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| UCB SA                           | UCB SA                                                 | CUSIP: N/A<br>LEI: 2138008J191VLSGY5A09       | Long             | EC               | CORP              | BE        |    550000 | NS      | $128592483.60 | 2.19%             |  |  |  | No            |                  1 | On Loan: No      |
| BEONE MEDICINES LTD              | BEONE MEDICINES LTD ADR                                | CUSIP: 07725L102<br>LEI: 549300JFUK6FRD5MH739 | Long             | EC               | CORP              | CH        |    100000 | NS      | $30605000.00  | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| RHYTHM PHARMACEUTICALS INC       | RHYTHM PHARMACEUTICALS INC                             | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |    228000 | NS      | $23518200.00  | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| RAPPORT THERAPEUTICS INC         | RAPPORT THERAPEUTICS INC                               | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    278632 | NS      | $4912282.16   | 0.08%             |  |  |  | No            |                  1 | On Loan: —       |
| ALNYLAM PHARMACEUTICALS INC      | ALNYLAM PHARMACEUTICALS INC                            | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |    535000 | NS      | $238882850.00 | 4.06%             |  |  |  | No            |                  1 | On Loan: No      |
| ZENAS BIOPHARMA INC              | ZENAS BIOPHARMA INC                                    | CUSIP: 98937L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    471101 | NS      | $7537616.00   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| CVS HEALTH CORP                  | CVS HEALTH CORP                                        | CUSIP: 126650100<br>LEI: 549300EJG376EN5NQE29 | Long             | EC               | CORP              | US        |   2320000 | NS      | $169708000.00 | 2.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Fidelity Revere Street Trust     | Fidelity Securities Lending Cash Central Fund          | CUSIP: 31635A303<br>LEI: 549300BDV45LJNXBZC55 | Long             | STIV             | RF                | US        | 110616270 | NS      | $110627331.53 | 1.88%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMUNOVANT INC                   | IMMUNOVANT INC                                         | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    757965 | NS      | $11134505.85  | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| VEEVA SYS INC                    | VEEVA SYS INC CL A                                     | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |    500000 | NS      | $134600000.00 | 2.29%             |  |  |  | No            |                  1 | On Loan: No      |
| XENON PHARMACEUTICALS INC        | XENON PHARMACEUTICALS INC                              | CUSIP: 98420N105<br>LEI: 549300XV44Q9Z1MIPQ03 | Long             | EC               | CORP              | CA        |   1280000 | NS      | $49548800.00  | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| WUGEN INC                        | WUGEN INC CONV 0% 12/31/2199 P/P                       | CUSIP: N/A<br>LEI: N/A                        | Long             | DBT              | CORP              | US        |   2299153 | PA      | $2747028.00   | 0.05%             | 2199-12-31      | Variable      | 0.00%                 | Yes           |                  3 | On Loan: No      |
| COGENT BIOSCIENCES INC           | COGENT BIOSCIENCES INC                                 | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   3380000 | NS      | $40830400.00  | 0.69%             |  |  |  | No            |                  1 | On Loan: No      |
| CG ONCOLOGY INC                  | CG ONCOLOGY INC                                        | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    690000 | NS      | $18505800.00  | 0.31%             |  |  |  | No            |                  1 | On Loan: —       |
| BRIGHTSPRING HEALTH SERVICES INC | BRIGHTSPRING HEALTH SERVICES INC                       | CUSIP: 10950A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   3850000 | NS      | $91206500.00  | 1.55%             |  |  |  | No            |                  1 | On Loan: —       |
| OCULAR THERAPEUTIX INC           | OCULAR THERAPEUTIX INC                                 | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |    262397 | NS      | $3203867.37   | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| INSMED INC                       | INSMED INC                                             | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    430000 | NS      | $58523000.00  | 0.99%             |  |  |  | No            |                  1 | On Loan: No      |
| HEARTFLOW INC                    | HEARTFLOW INC                                          | CUSIP: 42238D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11200 | NS      | $352800.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MEDICAL MICROINSTRUMENTS INC     | MEDICAL MICROINSTRUMENTS INC WT 02/16/2031 PP          | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |     15815 | NS      | $192310.40    | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| INSPIRE MEDICAL SYSTEMS INC      | INSPIRE MEDICAL SYSTEMS INC                            | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |    264200 | NS      | $24752898.00  | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| GILEAD SCIENCES INC              | GILEAD SCIENCES INC                                    | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |    900000 | NS      | $101673000.00 | 1.73%             |  |  |  | No            |                  1 | On Loan: No      |
| UNITEDHEALTH GROUP INC           | UNITEDHEALTH GROUP INC                                 | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |    495000 | NS      | $153385650.00 | 2.61%             |  |  |  | No            |                  1 | On Loan: No      |
| VIKING THERAPEUTICS INC          | VIKING THERAPEUTICS INC                                | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    690000 | NS      | $18664500.00  | 0.32%             |  |  |  | No            |                  1 | On Loan: —       |
| APOGEE THERAPEUTICS INC          | APOGEE THERAPEUTICS INC                                | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     64021 | NS      | $2328443.77   | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| KARDIUM INC/US                   | KARDIUM SRE D-7 PC PP (REDOMICILE CLOSING AUGUST 2025) | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |  15888877 | NS      | $9056659.89   | 0.15%             |  |  |  | No            |                  3 | On Loan: No      |
| REPLIGEN CORP                    | REPLIGEN                                               | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |    370000 | NS      | $45258400.00  | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| MERUS NV                         | MERUS B.V.                                             | CUSIP: N/A<br>LEI: 549300W8GPUWU8QNU293       | Long             | EC               | CORP              | NL        |   1040000 | NS      | $68473600.00  | 1.16%             |  |  |  | No            |                  1 | On Loan: No      |
| CIDARA THERAPEUTICS INC          | CIDARA THERAPEUTICS INC                                | CUSIP: 171757206<br>LEI: 549300IHQ9Z7RI1X2D22 | Long             | EC               | CORP              | US        |    210000 | NS      | $13731900.00  | 0.23%             |  |  |  | No            |                  1 | On Loan: —       |
| INSULET CORP                     | INSULET CORP                                           | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |    560000 | NS      | $190332800.00 | 3.24%             |  |  |  | No            |                  1 | On Loan: No      |
| ELEVATEBIO, LLC                  | ELEVATEBIO LLC SER C PC PP                             | CUSIP: N/A<br>LEI: N/A                        | Long             | EP               | CORP              | US        |    254900 | NS      | $532741.00    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| MASIMO CORP                      | MASIMO CORP                                            | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |   1481519 | NS      | $206983019.49 | 3.52%             |  |  |  | No            |                  1 | On Loan: No      |
| NUVALENT INC                     | NUVALENT INC-A                                         | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    715000 | NS      | $54754700.00  | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| CONTINEUM THERAPEUTICS INC       | CONTINEUM THERAPEUTICS INC CL A                        | CUSIP: 21217B100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    450000 | NS      | $4702500.00   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-09-30

**Name of Applicant:** Stacie M. Smith

**Signature:** Stacie M. Smith

**Name of Signer:** Stacie M. Smith

**Title:** President and Treasurer