# EDGAR Filing Document

**Accession Number:** 0002020584
**File Stem:** 0002020584-26-000001
**Filing Date:** 2026-4
**Character Count:** 3467
**Document Hash:** fd58046f11e5be8a09ae806764d01f8d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0002020584-26-000001.hdr.sgml**: 20260406

**ACCESSION NUMBER**: 0002020584-26-000001

**CONFORMED SUBMISSION TYPE**: C-AR

**PUBLIC DOCUMENT COUNT**: 11

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260406

**DATE AS OF CHANGE**: 20260406

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Siren Biotechnology, Inc.
- **CENTRAL INDEX KEY:** 0002020584

**ORGANIZATION NAME:**
- **EIN:** 853083204
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** C-AR
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 020-35739
- **FILM NUMBER:** 26840970

**BUSINESS ADDRESS:**
- **STREET 1:** 953 INDIANA STREET
- **CITY:** SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94107
- **BUSINESS PHONE:** 628-758-8536

**MAIL ADDRESS:**
- **STREET 1:** 953 INDIANA STREET
- **CITY:** SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94107

## Ex-99

### Attached PDF Documents

**Attachment 1:** `document_1.pdf`

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**Attachment 2:** `document_2.pdf`

_No text found in this document._

**Attachment 3:** `document_3.pdf`

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**Attachment 4:** `document_4.pdf`

_No text found in this document._

**Attachment 5:** `document_5.pdf`

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**Attachment 6:** `document_6.pdf`

_No text found in this document._

**Attachment 7:** `document_7.pdf`

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**Attachment 8:** `document_8.pdf`

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**Attachment 9:** `document_9.pdf`

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### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM C

### UNDER THE SECURITIES ACT OF 1933

### Issuer Information

**Name of Issuer:** Siren Biotechnology, Inc

**Legal Status:** Corporation

**Jurisdiction of Incorporation/Organization:** DE

**Date of Organization:** 09-14-2020

**Physical Address:** 953 Indiana Street, San Francisco, CA, 94107

**Issuer Website:** https://www.sirenbiotechnology.com/

**Is there a Co-Issuer?:** No

### Annual Report Disclosure Requirements

**Current Number of Employees:** 5

**Total Assets (Most Recent Fiscal Year):** $12,018,000.00

**Total Assets (Prior Fiscal Year):** $17,539,808.00

**Cash & Cash Equivalents (Most Recent Fiscal Year):** $11,934,000.00

**Cash & Cash Equivalents (Prior Fiscal Year):** $17,448,263.00

**Accounts Receivable (Most Recent Fiscal Year):** $0.00

**Accounts Receivable (Prior Fiscal Year):** $0.00

**Short-Term Debt (Most Recent Fiscal Year):** $377,000.00

**Short-Term Debt (Prior Fiscal Year):** $784,882.00

**Long-Term Debt (Most Recent Fiscal Year):** $0.00

**Long-Term Debt (Prior Fiscal Year):** $0.00

**Revenues/Sales (Most Recent Fiscal Year):** $0.00

**Revenues/Sales (Prior Fiscal Year):** $0.00

**Cost of Goods Sold (Most Recent Fiscal Year):** $0.00

**Cost of Goods Sold (Prior Fiscal Year):** $0.00

**Taxes Paid (Most Recent Fiscal Year):** $0.00

**Taxes Paid (Prior Fiscal Year):** $0.00

**Net Income (Most Recent Fiscal Year):** $-10,884,000.00

**Net Income (Prior Fiscal Year):** $-4,666,672.00

### Signatures

**Issuer:** Siren Biotechnology, Inc

**Signature:** Dr. Nicole K. Paulk, PhD

**Title:** CEO, Founder, and President

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**Signature:** Dr. Nicole K. Paulk, PhD

**Title:** CEO, Founder, and President

**Date:** 04-02-2026

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**Signature:** Dr. Stefano Gurciullo

**Title:** Director

**Date:** 04-02-2026