# EDGAR Filing Document

**Accession Number:** 0001446159
**File Stem:** 0001171843-25-004690
**Filing Date:** 2025-7
**Character Count:** 3056
**Document Hash:** fb3e5363348018382c132b7ee924a240
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001171843-25-004690.hdr.sgml**: 20250825

**ACCESSION NUMBER**: 0001171843-25-004690

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20250724

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Predictive Oncology Inc.
- **CENTRAL INDEX KEY:** 0001446159
- **STANDARD INDUSTRIAL CLASSIFICATION:** ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 331007393
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 91 43RD STREET
- **STREET 2:** SUITE 110
- **CITY:** PITTSBURGH
- **STATE:** PA
- **ZIP:** 15201
- **BUSINESS PHONE:** 412-432-1500

**MAIL ADDRESS:**
- **STREET 1:** 91 43RD STREET
- **STREET 2:** SUITE 110
- **CITY:** PITTSBURGH
- **STATE:** PA
- **ZIP:** 15201

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Precision Therapeutics Inc.
- **DATE OF NAME CHANGE:** 20180314

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Precision Therapeutic Inc.
- **DATE OF NAME CHANGE:** 20180208

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Skyline Medical Inc.
- **DATE OF NAME CHANGE:** 20130807

PREDICTIVE ONCOLOGY INC.

91 43rd Street, Suite 110

Pittsburgh, PA 15201

July 24, 2025

*<u>VIA EDGAR</u>*

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attention: Margaret Sawicki

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| | |
|:---|:---|
| **Re:** | **Predictive Oncology Inc.** |

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**Acceleration Request for Registration Statement on Form S-1**

**File No. 333-288782**

**Requested Date: July 28, 2025**

**Requested Time: 5:00 P.M. Eastern Time**

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Predictive Oncology Inc. (the "***Registrant***") hereby requests that the above-referenced Registration Statement on Form S-1 (File No. 333-288782) (the "***Registration Statement***") be declared effective at the "Requested Date" and "Requested Time" set forth above, or as soon as practicable thereafter, or at such later time as the Registrant or its counsel may orally request (the "***Registration Statement Acceleration Request***") via telephone call to the staff (the "***Staff***") of the Division of Corporation Finance of the Securities and Exchange Commission (the "***Commission***"). The Registrant hereby authorizes Amanda Maki of DLA Piper LLP (US), counsel for the Registrant, to make such request on the Registrant's behalf.

We request that we be notified of the effectiveness of the Registration Statement by telephone to Amanda Maki at 713-425-8461. Thank you for your assistance.

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| |
|:---|
| Very truly yours, |
| /s/ Josh Blacher |
| Josh Blacher |
| Interim Chief Financial Officer |

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cc: Raymond Vennare (Chief Executive Officer, Predictive Oncology Inc.)

Sara Turken (General Counsel, Predictive Oncology Inc.)

Amanda Maki (DLA Piper LLP (US))