# EDGAR Filing Document

**Accession Number:** 0000729528
**File Stem:** 0000051931-26-000357
**Filing Date:** 2026-3
**Character Count:** 86268
**Document Hash:** 619e3f0e26cdbb35d9a103cbf290d4f5
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000051931-26-000357.hdr.sgml**: 20260325

**ACCESSION NUMBER**: 0000051931-26-000357

**CONFORMED SUBMISSION TYPE**: 24F-2NT

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260325

**DATE AS OF CHANGE**: 20260325

**EFFECTIVENESS DATE**: 20260325

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** AMERICAN FUNDS INSURANCE SERIES
- **CENTRAL INDEX KEY:** 0000729528

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MA
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 24F-2NT
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 002-86838
- **FILM NUMBER:** 26789227

**BUSINESS ADDRESS:**
- **STREET 1:** 333 S HOPE ST - 55TH FL
- **CITY:** LOS ANGELES
- **STATE:** CA
- **ZIP:** 90071
- **BUSINESS PHONE:** 213-486-9200

**MAIL ADDRESS:**
- **STREET 1:** 333 S HOPE ST - 55TH FL
- **CITY:** LOS ANGELES
- **STATE:** CA
- **ZIP:** 90071

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMERICAN FUND INSURANCE SERIES
- **DATE OF NAME CHANGE:** 20010829

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMERICAN VARIABLE INSURANCE SERIES
- **DATE OF NAME CHANGE:** 19920703

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMERICAN PATHWAY FUND
- **DATE OF NAME CHANGE:** 19880531

## Series and Classes Contracts Data

### Global Growth Fund (Series ID: S000008786)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023903 |
| Class 2    | C000023904 |
| Class 4    | C000121502 |
| Class 1A   | C000176234 |

---

### American High-Income Trust (Series ID: S000008787)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023905 |
| Class 2    | C000023906 |
| Class 3    | C000023907 |
| Class 4    | C000121503 |
| Class 1A   | C000176235 |

---

### U.S. Government Securities Fund (Series ID: S000008788)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023908 |
| Class 2    | C000023909 |
| Class 3    | C000023910 |
| Class 4    | C000121504 |
| Class 1A   | C000176236 |

---

### Ultra-Short Bond Fund (Series ID: S000008789)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023911 |
| Class 2    | C000023912 |
| Class 3    | C000023913 |
| Class 4    | C000121505 |
| Class 1A   | C000176237 |

---

### SMALLCAP World Fund (Series ID: S000008790)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023914 |
| Class 2    | C000023915 |
| Class 4    | C000121506 |
| Class 1A   | C000176238 |

---

### Growth Fund (Series ID: S000008791)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023916 |
| Class 2    | C000023917 |
| Class 3    | C000023918 |
| Class 4    | C000121507 |
| Class 1A   | C000176239 |

---

### EUPAC Fund (Series ID: S000008792)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023919 |
| Class 2    | C000023920 |
| Class 3    | C000023921 |
| Class 4    | C000121508 |
| Class 1A   | C000176240 |

---

### New World Fund (Series ID: S000008793)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023922 |
| Class 2    | C000023923 |
| Class 4    | C000121509 |
| Class 1A   | C000176241 |

---

### Washington Mutual Investors Fund (Series ID: S000008794)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023924 |
| Class 2    | C000023925 |
| Class 4    | C000121510 |
| Class 1A   | C000176242 |

---

### Growth-Income Fund (Series ID: S000008795)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023926 |
| Class 2    | C000023927 |
| Class 3    | C000023928 |
| Class 4    | C000121511 |
| Class 1A   | C000176243 |

---

### Asset Allocation Fund (Series ID: S000008796)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023929 |
| Class 2    | C000023930 |
| Class 3    | C000023931 |
| Class 4    | C000121512 |
| Class 1A   | C000176244 |

---

### The Bond Fund of America (Series ID: S000008797)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000023932 |
| Class 2    | C000023933 |
| Class 4    | C000121513 |
| Class 1A   | C000176245 |

---

### Capital World Growth and Income Fund (Series ID: S000013710)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000037623 |
| Class 2    | C000037624 |
| Class 4    | C000121514 |
| Class 1A   | C000176246 |

---

### Capital World Bond Fund (Series ID: S000013796)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000037827 |
| Class 2    | C000037828 |
| Class 4    | C000121515 |
| Class 1A   | C000176247 |

---

### International Growth and Income Fund (Series ID: S000023461)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000068980 |
| Class 2    | C000068981 |
| Class 4    | C000121516 |
| Class 1A   | C000176248 |

---

### American Funds Global Balanced Fund (Series ID: S000031859)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000099201 |
| Class 2    | C000099202 |
| Class 4    | C000121517 |
| Class 1A   | C000176249 |

---

### American Funds Mortgage Fund (Series ID: S000031860)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000099203 |
| Class 2    | C000099204 |
| Class 4    | C000121518 |
| Class 1A   | C000176250 |

---

### Managed Risk Asset Allocation Fund (Series ID: S000038240)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000117906 |
| Class P2   | C000117907 |

---

### Managed Risk Growth Fund (Series ID: S000040665)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126054 |
| Class P2   | C000126055 |

---

### Managed Risk International Fund (Series ID: S000040666)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126056 |
| Class P2   | C000126057 |

---

### Managed Risk Washington Mutual Investors Fund (Series ID: S000040667)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126058 |
| Class P2   | C000126059 |

---

### Managed Risk Growth-Income Fund (Series ID: S000040668)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000126060 |
| Class P2   | C000126061 |

---

### Capital Income Builder (Series ID: S000045163)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000140604 |
| Class 2    | C000140605 |
| Class 4    | C000140606 |
| Class 1A   | C000176252 |

---

### Portfolio Series - American Funds Global Growth Portfolio (Series ID: S000048970)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000154330 |
| Class 2    | C000154331 |
| Class 4    | C000154332 |
| Class 1A   | C000176253 |

---

### Portfolio Series - American Funds Growth and Income Portfolio (Series ID: S000048971)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000154333 |
| Class 2    | C000154334 |
| Class 4    | C000154335 |
| Class 1A   | C000176254 |

---

### Portfolio Series - American Funds Managed Risk Global Allocation Portfolio (Series ID: S000048972)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000154336 |
| Class P2   | C000154337 |

---

### Portfolio Series - American Funds Managed Risk Growth Portfolio (Series ID: S000048973)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P2   | C000154338 |
| Class P1   | C000154339 |

---

### Portfolio Series - American Funds Managed Risk Growth and Income Portfolio (Series ID: S000048974)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class P1   | C000154340 |
| Class P2   | C000154341 |

---

### American Funds IS 2010 Target Date Fund (Series ID: S000067189)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000216157 |
| Class 1    | C000216158 |
| Class 2    | C000216159 |
| Class 4    | C000216160 |

---

### American Funds IS 2015 Target Date Fund (Series ID: S000067190)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000216161 |
| Class 1A   | C000216162 |
| Class 1    | C000216163 |
| Class 2    | C000216164 |

---

### American Funds IS 2020 Target Date Fund (Series ID: S000067191)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000216165 |
| Class 2    | C000216166 |
| Class 1A   | C000216167 |
| Class 1    | C000216168 |

---

### American Funds IS 2025 Target Date Fund (Series ID: S000067192)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000216169 |
| Class 2    | C000216170 |
| Class 4    | C000216171 |
| Class 1    | C000216172 |

---

### American Funds IS 2030 Target Date Fund (Series ID: S000067193)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000216173 |
| Class 2    | C000216174 |
| Class 4    | C000216175 |
| Class 1    | C000216176 |

---

### American Funds IS 2035 Target Date Fund (Series ID: S000067194)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000216177 |
| Class 1A   | C000216178 |
| Class 2    | C000216179 |
| Class 4    | C000216180 |

---

### American Funds IS 2040 Target Date Fund (Series ID: S000080323)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000242643 |
| Class 1    | C000242644 |
| Class 2    | C000242645 |
| Class 4    | C000242646 |

---

### American Funds IS 2045 Target Date Fund (Series ID: S000080324)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000242647 |
| Class 1A   | C000242648 |
| Class 1    | C000242649 |
| Class 2    | C000242650 |

---

### American Funds IS 2050 Target Date Fund (Series ID: S000080325)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000242651 |
| Class 2    | C000242652 |
| Class 1A   | C000242653 |
| Class 1    | C000242654 |

---

### American Funds IS 2055 Target Date Fund (Series ID: S000080326)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000242655 |
| Class 2    | C000242656 |
| Class 4    | C000242657 |
| Class 1    | C000242658 |

---

### American Funds IS 2060 Target Date Fund (Series ID: S000080327)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1A   | C000242659 |
| Class 2    | C000242660 |
| Class 4    | C000242661 |
| Class 1    | C000242662 |

---

### American Funds IS 2065 Target Date Fund (Series ID: S000080328)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 1    | C000242663 |
| Class 1A   | C000242664 |
| Class 2    | C000242665 |
| Class 4    | C000242666 |

---

### American Funds IS 2070 Target Date Fund (Series ID: S000084732)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000249197 |
| Class 1    | C000249198 |
| Class 1A   | C000249199 |
| Class 2    | C000249200 |

---

### U.S. Small and Mid Cap Equity Fund (Series ID: S000088658)

---

|  |  |
|:---|:---|
| Class Name | Class ID   |
| Class 4    | C000254989 |
| Class 1    | C000254990 |
| Class 1A   | C000254991 |
| Class 2    | C000254992 |

---

## Series and Classes Contracts Data

### Global Growth Fund (Series ID: S000008786)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023903 | Class 1      |  |
| C000023904 | Class 2      |  |
| C000121502 | Class 4      |  |
| C000176234 | Class 1A     |  |

### American High-Income Trust (Series ID: S000008787)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023905 | Class 1      |  |
| C000023906 | Class 2      |  |
| C000023907 | Class 3      |  |
| C000121503 | Class 4      |  |
| C000176235 | Class 1A     |  |

### U.S. Government Securities Fund (Series ID: S000008788)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023908 | Class 1      |  |
| C000023909 | Class 2      |  |
| C000023910 | Class 3      |  |
| C000121504 | Class 4      |  |
| C000176236 | Class 1A     |  |

### Ultra-Short Bond Fund (Series ID: S000008789)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023911 | Class 1      |  |
| C000023912 | Class 2      |  |
| C000023913 | Class 3      |  |
| C000121505 | Class 4      |  |
| C000176237 | Class 1A     |  |

### SMALLCAP World Fund (Series ID: S000008790)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023914 | Class 1      |  |
| C000023915 | Class 2      |  |
| C000121506 | Class 4      |  |
| C000176238 | Class 1A     |  |

### Growth Fund (Series ID: S000008791)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023916 | Class 1      |  |
| C000023917 | Class 2      |  |
| C000023918 | Class 3      |  |
| C000121507 | Class 4      |  |
| C000176239 | Class 1A     |  |

### EUPAC Fund (Series ID: S000008792)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023919 | Class 1      |  |
| C000023920 | Class 2      |  |
| C000023921 | Class 3      |  |
| C000121508 | Class 4      |  |
| C000176240 | Class 1A     |  |

### New World Fund (Series ID: S000008793)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023922 | Class 1      |  |
| C000023923 | Class 2      |  |
| C000121509 | Class 4      |  |
| C000176241 | Class 1A     |  |

### Washington Mutual Investors Fund (Series ID: S000008794)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023924 | Class 1      |  |
| C000023925 | Class 2      |  |
| C000121510 | Class 4      |  |
| C000176242 | Class 1A     |  |

### Growth-Income Fund (Series ID: S000008795)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023926 | Class 1      |  |
| C000023927 | Class 2      |  |
| C000023928 | Class 3      |  |
| C000121511 | Class 4      |  |
| C000176243 | Class 1A     |  |

### Asset Allocation Fund (Series ID: S000008796)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023929 | Class 1      |  |
| C000023930 | Class 2      |  |
| C000023931 | Class 3      |  |
| C000121512 | Class 4      |  |
| C000176244 | Class 1A     |  |

### The Bond Fund of America (Series ID: S000008797)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000023932 | Class 1      |  |
| C000023933 | Class 2      |  |
| C000121513 | Class 4      |  |
| C000176245 | Class 1A     |  |

### Capital World Growth and Income Fund (Series ID: S000013710)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000037623 | Class 1      |  |
| C000037624 | Class 2      |  |
| C000121514 | Class 4      |  |
| C000176246 | Class 1A     |  |

### Capital World Bond Fund (Series ID: S000013796)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000037827 | Class 1      |  |
| C000037828 | Class 2      |  |
| C000121515 | Class 4      |  |
| C000176247 | Class 1A     |  |

### International Growth and Income Fund (Series ID: S000023461)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000068980 | Class 1      |  |
| C000068981 | Class 2      |  |
| C000121516 | Class 4      |  |
| C000176248 | Class 1A     |  |

### American Funds Global Balanced Fund (Series ID: S000031859)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000099201 | Class 1      |  |
| C000099202 | Class 2      |  |
| C000121517 | Class 4      |  |
| C000176249 | Class 1A     |  |

### American Funds Mortgage Fund (Series ID: S000031860)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000099203 | Class 1      |  |
| C000099204 | Class 2      |  |
| C000121518 | Class 4      |  |
| C000176250 | Class 1A     |  |

### Managed Risk Asset Allocation Fund (Series ID: S000038240)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000117906 | Class P1     |  |
| C000117907 | Class P2     |  |

### Managed Risk Growth Fund (Series ID: S000040665)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126054 | Class P1     |  |
| C000126055 | Class P2     |  |

### Managed Risk International Fund (Series ID: S000040666)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126056 | Class P1     |  |
| C000126057 | Class P2     |  |

### Managed Risk Washington Mutual Investors Fund (Series ID: S000040667)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126058 | Class P1     |  |
| C000126059 | Class P2     |  |

### Managed Risk Growth-Income Fund (Series ID: S000040668)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000126060 | Class P1     |  |
| C000126061 | Class P2     |  |

### Capital Income Builder (Series ID: S000045163)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000140604 | Class 1      |  |
| C000140605 | Class 2      |  |
| C000140606 | Class 4      |  |
| C000176252 | Class 1A     |  |

### Portfolio Series - American Funds Global Growth Portfolio (Series ID: S000048970)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154330 | Class 1      |  |
| C000154331 | Class 2      |  |
| C000154332 | Class 4      |  |
| C000176253 | Class 1A     |  |

### Portfolio Series - American Funds Growth and Income Portfolio (Series ID: S000048971)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154333 | Class 1      |  |
| C000154334 | Class 2      |  |
| C000154335 | Class 4      |  |
| C000176254 | Class 1A     |  |

### Portfolio Series - American Funds Managed Risk Global Allocation Portfolio (Series ID: S000048972)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154336 | Class P1     |  |
| C000154337 | Class P2     |  |

### Portfolio Series - American Funds Managed Risk Growth Portfolio (Series ID: S000048973)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154338 | Class P2     |  |
| C000154339 | Class P1     |  |

### Portfolio Series - American Funds Managed Risk Growth and Income Portfolio (Series ID: S000048974)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000154340 | Class P1     |  |
| C000154341 | Class P2     |  |

### American Funds IS 2010 Target Date Fund (Series ID: S000067189)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216157 | Class 1A     |  |
| C000216158 | Class 1      |  |
| C000216159 | Class 2      |  |
| C000216160 | Class 4      |  |

### American Funds IS 2015 Target Date Fund (Series ID: S000067190)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216161 | Class 4      |  |
| C000216162 | Class 1A     |  |
| C000216163 | Class 1      |  |
| C000216164 | Class 2      |  |

### American Funds IS 2020 Target Date Fund (Series ID: S000067191)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216165 | Class 4      |  |
| C000216166 | Class 2      |  |
| C000216167 | Class 1A     |  |
| C000216168 | Class 1      |  |

### American Funds IS 2025 Target Date Fund (Series ID: S000067192)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216169 | Class 1A     |  |
| C000216170 | Class 2      |  |
| C000216171 | Class 4      |  |
| C000216172 | Class 1      |  |

### American Funds IS 2030 Target Date Fund (Series ID: S000067193)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216173 | Class 1A     |  |
| C000216174 | Class 2      |  |
| C000216175 | Class 4      |  |
| C000216176 | Class 1      |  |

### American Funds IS 2035 Target Date Fund (Series ID: S000067194)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000216177 | Class 1      |  |
| C000216178 | Class 1A     |  |
| C000216179 | Class 2      |  |
| C000216180 | Class 4      |  |

### American Funds IS 2040 Target Date Fund (Series ID: S000080323)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000242643 | Class 1A     |  |
| C000242644 | Class 1      |  |
| C000242645 | Class 2      |  |
| C000242646 | Class 4      |  |

### American Funds IS 2045 Target Date Fund (Series ID: S000080324)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000242647 | Class 4      |  |
| C000242648 | Class 1A     |  |
| C000242649 | Class 1      |  |
| C000242650 | Class 2      |  |

### American Funds IS 2050 Target Date Fund (Series ID: S000080325)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000242651 | Class 4      |  |
| C000242652 | Class 2      |  |
| C000242653 | Class 1A     |  |
| C000242654 | Class 1      |  |

### American Funds IS 2055 Target Date Fund (Series ID: S000080326)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000242655 | Class 1A     |  |
| C000242656 | Class 2      |  |
| C000242657 | Class 4      |  |
| C000242658 | Class 1      |  |

### American Funds IS 2060 Target Date Fund (Series ID: S000080327)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000242659 | Class 1A     |  |
| C000242660 | Class 2      |  |
| C000242661 | Class 4      |  |
| C000242662 | Class 1      |  |

### American Funds IS 2065 Target Date Fund (Series ID: S000080328)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000242663 | Class 1      |  |
| C000242664 | Class 1A     |  |
| C000242665 | Class 2      |  |
| C000242666 | Class 4      |  |

### American Funds IS 2070 Target Date Fund (Series ID: S000084732)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000249197 | Class 4      |  |
| C000249198 | Class 1      |  |
| C000249199 | Class 1A     |  |
| C000249200 | Class 2      |  |

### U.S. Small and Mid Cap Equity Fund (Series ID: S000088658)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000254989 | Class 4      |  |
| C000254990 | Class 1      |  |
| C000254991 | Class 1A     |  |
| C000254992 | Class 2      |  |

## FORM 24F-2NT: Annual Notice of Securities Sold Pursuant to Rule 24f-2

### 24F-2NT: Filer Information

**Filer CIK:** 0000729528

**Is this a LIVE or TEST Filing?:** LIVE

**Filer Investment Company Type:** N-1A

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $8639060000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $5953064000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $9032636000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $14985700000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-6346640000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $8112165000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $6556183000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $9554247000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $16110430000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-7998265000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $260292000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $168611000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $915197000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1083808000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-823516000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $136341000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $166829000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $433525000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $600354000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-464013000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $415925000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $416412000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1514052000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1930464000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1514539000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $26633000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $16299000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $213411000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $229710000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-203077000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $79906000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $101521000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1202025000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1303546000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1223640000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $186680000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $771657000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $2152445000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2924102000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-2737422000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $85171000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $71489000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $28248000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $99737000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-14566000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $40708000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $98035000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $88856000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $186891000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-146183000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $3242274000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $4217986000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $2785998000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $7003984000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-3761710000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $456065000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1402667000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $3975315000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $5377982000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-4921917000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1561205000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1550618000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1305796000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2856414000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1295209000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $248819000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $391431000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1409621000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1801052000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1552233000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $265235000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $636067000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1312506000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1948573000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-1683338000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $576181000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $665380000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $460526000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1125906000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-549725000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1729902000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1175077000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $936407000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2111484000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-381582000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1904408000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $2024150000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2024150000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-119742000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $235153000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $290457000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $765397000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1055854000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-820701000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $159826000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $344377000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $337479000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $681856000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-522030000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $4699000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $20283000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $15401000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $35684000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-30985000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $12984000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $46117000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $56816000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $102933000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-89949000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $260494000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $204308000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $204308000.00

- **(v) Net sales:** $56186000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $7759.29

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $4674000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $8854000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $6683000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $15537000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-10863000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $50284000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $48236000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $5696000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $53932000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-3648000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $42355000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $218652000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $140992000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $359644000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-317289000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $28914000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $187093000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $123820000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $310913000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-281999000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $5971000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $57874000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $42446000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $100320000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-94349000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $29973000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $73349000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $5459000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $78808000.00

- **(v) Net sales:** $0.00

- **(vi) Redemption credits available for use in future years:** $-48835000.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $0.00

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $59324000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $6203000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $6203000.00

- **(v) Net sales:** $53121000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $7336.01

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $24303000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $4057000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $4057000.00

- **(v) Net sales:** $20246000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $2795.97

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $33075000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $13439000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $13439000.00

- **(v) Net sales:** $19636000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $2711.73

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $46343000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $10609000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $10609000.00

- **(v) Net sales:** $35734000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $4934.87

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $26933000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $9073000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $1263000.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $10336000.00

- **(v) Net sales:** $16597000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $2292.05

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $19941000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $2219000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2219000.00

- **(v) Net sales:** $17722000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $2447.41

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $14345000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1062000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1062000.00

- **(v) Net sales:** $13283000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $1834.38

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $12431000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $2494000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $2494000.00

- **(v) Net sales:** $9937000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $1372.30

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $7022000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $1653000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $1653000.00

- **(v) Net sales:** $5369000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $741.46

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $949000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $339000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $339000.00

- **(v) Net sales:** $610000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $84.24

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $321000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $22000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $22000.00

- **(v) Net sales:** $299000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $41.29

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $1248000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $15000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $15000.00

- **(v) Net sales:** $1233000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $170.28

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland

### 24F-2NT: Annual Filing Information

**1. Name and address of issuer:**

- **Name of Issuer:** American Funds Insurance Series

- **Address:** 333 South Hope Street, Los Angeles, CA 90071

**2. The Name and EDGAR Identifier of each series or class of securities for which this Form is filed:**

- [ ] Check box if the Form is being filed for all series and classes of the issuer.

**3. Investment Company Act File Number:** 811-03857

   **Securities Act File Number:** 002-86838

**4(a). Last day of fiscal year for which this Form is filed:** 12/31/2025

**4(b). Check box if this Form is being filed late:** [ ]

**4(c). Check box if this is the last time the issuer will be filing this Form:** [ ]

**5. Calculation of registration fee:**

- **(i) Aggregate sale price of securities sold during the fiscal year:** $109548000.00

- **(ii) Aggregate price of securities redeemed or repurchased during the fiscal year:** $27639000.00

- **(iii) Aggregate price of securities redeemed or repurchased during any prior fiscal year:** $0.00

- **(iv) Total available redemption credits [add Items 5(ii) and 5(iii)]:** $27639000.00

- **(v) Net sales:** $81909000.00

- **(vi) Redemption credits available for use in future years:** $0.00

- **(vii) Multiplier for determining registration fee:** 0.000138100

- **(viii) Registration fee due:** $11311.63

**Explanatory Notes (if any):**
None

**Signatures**

**Name and Title:** Gregory F. Niland, Treasurer

**Date:** 03/25/2026

**Signature:** Gregory F. Niland