# EDGAR Filing Document

**Accession Number:** 0001218503
**File Stem:** 0001178913-23-000004
**Filing Date:** 2023-1
**Character Count:** 16109
**Document Hash:** 2b8ffe9d2a484155f548ef1574812edf
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001178913-23-000004.hdr.sgml**: 20230103

**ACCESSION NUMBER**: 0001178913-23-000004

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230103

**DATE AS OF CHANGE**: 20230103

**GROUP MEMBERS**: ANGELS INVESTMENTS IN HI TECH LTD

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Protalix BioTherapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001006281
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 650643773
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-50118
- **FILM NUMBER:** 23500032

**BUSINESS ADDRESS:**
- **STREET 1:** 2 UNIVERSITY PLAZA
- **STREET 2:** SUITE 100
- **CITY:** HACKENSACK
- **STATE:** NJ
- **ZIP:** 07601
- **BUSINESS PHONE:** 201-696-9345

**MAIL ADDRESS:**
- **STREET 1:** 2 UNIVERSITY PLAZA
- **STREET 2:** SUITE 100
- **CITY:** HACKENSACK
- **STATE:** NJ
- **ZIP:** 07601

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ORTHODONTIX INC
- **DATE OF NAME CHANGE:** 19980422

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** EMBASSY ACQUISITION CORP
- **DATE OF NAME CHANGE:** 19960124
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** NACHT MARIUS
- **CENTRAL INDEX KEY:** 0001218503

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**MAIL ADDRESS:**
- **STREET 1:** 18 YEHEZKEL ST
- **CITY:** TEL AVIV-YAFO
- **STATE:** L3
- **ZIP:** 6259524

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#### UNITED STATES<br> SECURITIES AND EXCHANGE COMMISSION <br> Washington, D.C. 20549

### SCHEDULE 13G/A

#### Under the Securities Exchange Act of 1934

### Protalix BioTherapeutics, Inc.

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(Name of Issuer)

#### Common Stock, Par Value $0.001 per Share

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(Title of Class of Securities)

#### 74365A309
(CUSIP Number)<br>

#### December 31, 2022

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(Date of Event which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

☒ Rule 13d-1(c)

☐ Rule 13d-1(d)

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act.

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| | | |
|:---|:---|:---|
| **CUSIP** <br> **NO.**<br> **** <br>| **74365A309** | **74365A309** |
| **1** | **NAMES OF REPORTING PERSONS** | **NAMES OF REPORTING PERSONS** |
| **1** | Angels Investments in Hi Tech Ltd<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). | Angels Investments in Hi Tech Ltd<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). |
| **1** | Angels Investments in Hi Tech Ltd<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). | Angels Investments in Hi Tech Ltd<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). |
| **2** | **CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP** | **CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP** |
| **2** | (a)☒ | (a)☒ |
| **2** | (b)☐ | (b)☐ |
| **3** | **SEC USE ONLY** | **SEC USE ONLY** |
| **3** |  |  |
| **3** |  |  |
| **4** | **CITIZENSHIP OR PLACE OF ORGANIZATION** | **CITIZENSHIP OR PLACE OF ORGANIZATION** |
| **4** | <br>Israel | <br>Israel |
| **4** | <br>Israel | <br>Israel |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **5** | **SOLE VOTING POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **5** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **5** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **6** | **SHARED VOTING POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **6** | <br>2,816,901 shares\* |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **6** | <br>2,816,901 shares\* |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **7** | **SOLE DISPOSITIVE POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **7** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **7** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **8** | **SHARED DISPOSITIVE POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **8** | <br>2,816,901 shares\* |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **8** | <br>2,816,901 shares\* |
| **9** | **AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON** | **AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON** |
| **9** | <br>2,816,901 shares\* | <br>2,816,901 shares\* |
| **9** | <br>2,816,901 shares\* | <br>2,816,901 shares\* |
| **10** | **CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)** | **CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)** |
| **10** | ☐ | ☐ |
| **10** | ☐ | ☐ |
| **11** | **PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)** | **PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)** |
| **11** | <br>5.3% | <br>5.3% |
| **11** | <br>5.3% | <br>5.3% |
| **12** | **TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)** | **TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)** |
| **12** | <br>CO  | <br>CO  |
| **12** | <br>CO  | <br>CO  |

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\* Consists of 2,816,901 shares of Common Stock of the Issuer that the Reporting Person has the right to acquire pursuant to warrants that are exercisable within 60 days of December 31, 2022

Page 2 of 7 Pages

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| | | |
|:---|:---|:---|
| **CUSIP** <br> **NO.**<br> **** <br>| **74365A309** | **74365A309** |
| **1** | **NAMES OF REPORTING PERSONS** | **NAMES OF REPORTING PERSONS** |
| **1** | Marius Nacht<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). | Marius Nacht<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). |
| **1** | Marius Nacht<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). | Marius Nacht<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). |
| **2** | **CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP** | **CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP** |
| **2** | (a)☒ | (a)☒ |
| **2** | (b)☐ | (b)☐ |
| **3** | **SEC USE ONLY** | **SEC USE ONLY** |
| **3** |  |  |
| **3** |  |  |
| **4** | **CITIZENSHIP OR PLACE OF ORGANIZATION** | **CITIZENSHIP OR PLACE OF ORGANIZATION** |
| **4** | <br>Israel | <br>Israel |
| **4** | <br>Israel | <br>Israel |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **5** | **SOLE VOTING POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **5** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **5** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **6** | **SHARED VOTING POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **6** | <br>2,816,901 shares\* |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **6** | <br>2,816,901 shares\* |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **7** | **SOLE DISPOSITIVE POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **7** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **7** | <br>0 |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **8** | **SHARED DISPOSITIVE POWER** |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **8** | <br>2,816,901 shares\* |
| **NUMBER OF<br> SHARES <br> BENEFICIALLY<br> OWNED BY <br> EACH <br>REPORTING <br> PERSON <br> WITH** | **8** | <br>2,816,901 shares\* |
| **9** | **AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON** | **AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON** |
| **9** | <br>2,816,901 shares\* | <br>2,816,901 shares\* |
| **9** | <br>2,816,901 shares\* | <br>2,816,901 shares\* |
| **10** | **CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)** | **CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)** |
| **10** | ☐ | ☐ |
| **10** | ☐ | ☐ |
| **11** | **PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)** | **PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)** |
| **11** | <br>5.3% | <br>5.3% |
| **11** | <br>5.3% | <br>5.3% |
| **12** | **TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)** | **TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)** |
| **12** | <br>IN | <br>IN |
| **12** | <br>IN | <br>IN |

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\* Consists of 2,816,901 shares of Common Stock of the Issuer that the Reporting Person has the right to acquire pursuant to warrants that are exercisable within 60 days of December 31, 2022

Page 3 of 7 Pages

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| | |
|:---|:---|
| **Item 1(a)** | **Name of Issuer**<br> **** <br>Protalix BioTherapeutics, Inc. (the "Issuer"). |

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| | |
|:---|:---|
| **Item 1(b)** | **Address of Issuer's Principal Executive Offices**<br> **** <br>2 Snunit Street, Science Park, POB 455, Carmiel 2161401, Israel |

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**Item 2(a)-(b) Name of Person Filing; Address of Principal Business Office or, if none, Residence**

<br> 1.<br> Angels Investments in Hi Tech Ltd. ("Angels") c/o Marius Nacht, 42 Brandeis St. Tel Aviv 6200157, Israel

<br> 2.<br> Marius Nacht, 42 Brandeis St. Tel Aviv 6200157, Israel

<br> The foregoing persons are hereinafter collectively referred to as the "Reporting Persons". <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

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| | |
|:---|:---|
| **Item 2(c)** | **Citizenship**<br> **** <br>Angels is an Israeli company; and Marius Nacht is an Israeli citizen.  |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <br>

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| | |
|:---|:---|
| **Item 2(d)** | **Title of Class of Securities**<br> **** <br>Common Stock, par value $0.001 per share |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

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| | |
|:---|:---|
| **Item 2(e)** | **CUSIP Number**<br> **** <br>74365A309 |

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| | |
|:---|:---|
| **Item 3** | **If this Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b) or (c), Check Whether the Person Filing is a:**<br> **** <br>**Not applicable.**  |

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| | |
|:---|:---|
| **Item 4**  | **Ownership**<br> **** <br>***Angels Investments in Hi Tech Ltd.***<br>|

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(a) <u>Amount beneficially owned</u>: 2,816,901 shares of Common Stock. The number of shares of Common Stock set forth above consists solely of 2,816,901 shares of Common Stock of the Issuer that the Reporting Person has the right to acquire pursuant to warrants that are exercisable within 60 days of December 31, 2022. All share percentage calculation are based on (i) 50,665,598 shares of Common Stock outstanding as of November 10, 2022, as reported by the Issuer to the SEC on Form 10-Q on November 14, 2022 and (ii) 2,816,901 shares of Common Stock of the Issuer that the Reporting Person has the right to acquire pursuant to warrants that are exercisable within 60 days of December 31, 2022, which are treated as issued and outstanding solely for the purpose of computing the percentage ownership of the Reporting Person pursuant to Rule 13d-3(d)(1)(i) under the Act. 

(b) <u>Percent of Class</u>: 5.3% 

Page 4 of 7 Pages

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<br> (c) <u>Number of shares as to which the person has</u>:

(i) Sole power to vote or direct the vote: 0

(ii) Shared power to vote or to direct the vote: 2,816,901 shares of Common Stock

<br> (iii) Sole power to dispose or to direct the disposition of: 0

<br> (iv) Shared power to dispose or to direct the disposition of: 2,816,901 shares of Common Stock

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| | |
|:---|:---|
|  | **Marius Nacht<br>** <br>|

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(a) <u>Amount beneficially owned</u>: 2,816,901 shares of Common Stock. Marius Nacht is the sole shareholder and director of Angels. By reason of Mr. Nacht's control over Angels, By virtue of such relationship, Marius Nacht may be deemed to have shared voting and investment power with respect to the shares of Common Stock of the Issuer held by Angels. The number of shares of Common Stock set forth above consists solely of 2,816,901 shares of Common Stock of the Issuer that the Reporting Person has the right to acquire pursuant to warrants that are exercisable within 60 days of December 31, 2022. All share percentage calculation are based on (i) 50,665,598 shares of Common Stock outstanding as of November 10, 2022, as reported by the Issuer to the SEC on Form 10-Q on November 14, 2022 and (ii) 2,816,901 shares of Common Stock of the Issuer that the Reporting Person has the right to acquire pursuant to warrants that are exercisable within 60 days of December 31, 2022, which are treated as issued and outstanding solely for the purpose of computing the percentage ownership of the Reporting Person pursuant to Rule 13d-3(d)(1)(i) under the Act. 

(b) <u>Percent of Class</u>: 5.3% 

<br> (c) <u>Number of shares as to which the person has</u>:

(i) Sole power to vote or direct the vote: 0

(ii) Shared power to vote or to direct the vote: 2,816,901 shares of Common Stock

<br> (iii) Sole power to dispose or to direct the disposition of: 0

<br> (iv) Shared power to dispose or to direct the disposition of: 2,816,901 shares of Common Stock

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| | |
|:---|:---|
| **Item 5**  | **Ownership of Five Percent or Less of a Class**<br> **** <br>**Not applicable.**  |

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| | |
|:---|:---|
| **Item 6** | **Ownership of More than Five Percent on Behalf of Another Person**<br> **** <br>**Not applicable.**  |

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| | |
|:---|:---|
| **Item 7** | **Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company**<br> **** <br>**Not applicable.**  |

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| | |
|:---|:---|
| **Item 8** | **Identification and Classification of Members of the Group**<br> **** <br>Incorporated by reference to Items 2 and 4 of this Schedule 13G. |

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| | |
|:---|:---|
| **Item 9**  | **Notice of Dissolution of Group**<br> **** <br>**Not applicable.**  |

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|:---|:---|
| **Item 10**  | **Certification**<br> **** <br>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. |

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Page 5 of 7 Pages

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#### Signature
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

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| | |
|:---|:---|
| Dated: January 3, 2023 | <br>**ANGELS INVESTMENTS IN HI TECH LTD.**<br>By: <u>/s/ Marius Nacht</u><br> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Name: Marius Nacht<br> &nbsp;&nbsp;&nbsp;&nbsp; Title: Sole Shareholder<br>**MARIUS NACHT**<br> **** <br>By: <u>/s/ Marius Nacht</u> |

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Page 6 of 6 Pages

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