# EDGAR Filing Document

**Accession Number:** 0001536196
**File Stem:** 0001213900-26-038553
**Filing Date:** 2026-4
**Character Count:** 2416
**Document Hash:** d87e655445717b515fefaa09f8c2326f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-26-038553.hdr.sgml**: 20260501

**ACCESSION NUMBER**: 0001213900-26-038553

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20260401

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Can-Fite BioPharma Ltd.
- **CENTRAL INDEX KEY:** 0001536196
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** L3
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 26 BEN GURION STREET
- **CITY:** RAMAT GAN
- **STATE:** L3
- **ZIP:** 5257346
- **BUSINESS PHONE:** 972 39241114

**MAIL ADDRESS:**
- **STREET 1:** 26 BEN GURION STREET
- **CITY:** RAMAT GAN
- **STATE:** L3
- **ZIP:** 5257346

**Can-Fite BioPharma Ltd.**

**26 Ben Gurion Street**

**Ramat Gan 5257346 Israel**

April 1, 2026

Securities and Exchange Commission<br> Division of Corporation Finance<br> 100 F Street, N.E.<br> Washington, D.C. 20549

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| | |
|:---|:---|
| **Re:** | **Can-Fite BioPharma Ltd.** |
|  | **Registration Statement on Form F-3**<br> **File No. 333-294760** |

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<u>VIA EDGAR</u>

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Can-Fite BioPharma Ltd. (the "**Registrant**") hereby respectfully requests that the effectiveness of the Registration Statement on Form F-3 (File No. 333-294760) of the Registrant (the "**Registration Statement**") be accelerated so that the Company's Registration Statement will be declared effective at 5:00 p.m., Eastern Time, on April 3, 2026 or as soon thereafter as may be practicable.

The undersigned respectfully requests that it be notified of the effectiveness of the Registration Statement by telephone call to our counsel, Greenberg Traurig, LLP, by calling Gary Emmanuel at (212) 801-9337. The Company hereby authorizes Mr. Emmanuel to orally modify or withdraw this request for acceleration.

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| | | |
|:---|:---|:---|
| Very truly yours, | Very truly yours, | Very truly yours, |
| CAN-FITE BIOPHARMA LTD. | CAN-FITE BIOPHARMA LTD. | CAN-FITE BIOPHARMA LTD. |
| By: | /s/ Motti Farbstein | /s/ Motti Farbstein |
|  | Name: | Motti Farbstein |
|  | Title: | Chief Executive Officer and |
|  |  | Chief Financial Officer |

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cc: Gary Emmanuel (Greenberg Traurig, LLP)