# EDGAR Filing Document

**Accession Number:** 0001326732
**File Stem:** 0001628280-23-003750
**Filing Date:** 2023-2
**Character Count:** 9728
**Document Hash:** 36a6b2ae455ede16ddf527a57e93824e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001628280-23-003750.hdr.sgml**: 20230215

**ACCESSION NUMBER**: 0001628280-23-003750

**CONFORMED SUBMISSION TYPE**: SC 13G

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230215

**DATE AS OF CHANGE**: 20230215

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Inmune Bio, Inc.
- **CENTRAL INDEX KEY:** 0001711754
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 475205835
- **STATE OF INCORPORATION:** NV
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-90859
- **FILM NUMBER:** 23636250

**BUSINESS ADDRESS:**
- **STREET 1:** 225 NE MIZNER BLVD, SUITE 640
- **CITY:** BOCA RATON
- **STATE:** FL
- **ZIP:** 33432
- **BUSINESS PHONE:** 8589643720

**MAIL ADDRESS:**
- **STREET 1:** 225 NE MIZNER BLVD, SUITE 640
- **CITY:** BOCA RATON
- **STATE:** FL
- **ZIP:** 33432
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Xencor Inc
- **CENTRAL INDEX KEY:** 0001326732
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 201622502
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G

**BUSINESS ADDRESS:**
- **STREET 1:** 111 WEST LEMON AVE
- **CITY:** MONROVIA
- **STATE:** CA
- **ZIP:** 91016
- **BUSINESS PHONE:** 626-305-5900

**MAIL ADDRESS:**
- **STREET 1:** 111 WEST LEMON AVE
- **CITY:** MONROVIA
- **STATE:** CA
- **ZIP:** 91016

---

| |
|:---|
| **SECURITIES AND EXCHANGE COMMISSION** |
| **Washington, DC 20549** |

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**SCHEDULE 13G**

**Under the Securities Exchange Act of 1934**

**(Amendment No. 2)\***

**INmune Bio, Inc.**

(Name of Issuer)

**Common Stock, par value $0.001 per share**

(Title of Class of Securities)

**45782T105**

(CUSIP Number)

**December 31, 2022**

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

☐ Rule 13d-1(c)

☒ Rule 13d-1(d)

\*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

------

<u>CUSIP No. 45782T105</u>

&nbsp;&nbsp;&nbsp;&nbsp;

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| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;1 | &nbsp;&nbsp;&nbsp;&nbsp;NAMES OF REPORTING PERSONS<br> Xencor, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;NAMES OF REPORTING PERSONS<br> Xencor, Inc. | &nbsp;&nbsp;&nbsp;&nbsp;NAMES OF REPORTING PERSONS<br> Xencor, Inc. |
| &nbsp;&nbsp; 2 | &nbsp;&nbsp;&nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)<br>&nbsp;&nbsp;&nbsp;&nbsp;(a) ☐&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) ☒ | &nbsp;&nbsp;&nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)<br>&nbsp;&nbsp;&nbsp;&nbsp;(a) ☐&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) ☒ | &nbsp;&nbsp;&nbsp;&nbsp;CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)<br>&nbsp;&nbsp;&nbsp;&nbsp;(a) ☐&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) ☒ |
| &nbsp;&nbsp; 3 | &nbsp;&nbsp;&nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;&nbsp;&nbsp;SEC USE ONLY | &nbsp;&nbsp;&nbsp;&nbsp;SEC USE ONLY |
| &nbsp;&nbsp; 4 | &nbsp;&nbsp;&nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br>&nbsp;&nbsp;&nbsp;&nbsp;Delaware | &nbsp;&nbsp;&nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br>&nbsp;&nbsp;&nbsp;&nbsp;Delaware | &nbsp;&nbsp;&nbsp;&nbsp;CITIZENSHIP OR PLACE OF ORGANIZATION<br>&nbsp;&nbsp;&nbsp;&nbsp;Delaware |
| NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | 5 | &nbsp;&nbsp;&nbsp;&nbsp;SOLE VOTING POWER<br>&nbsp;&nbsp;&nbsp;&nbsp;1,885,533 |
| NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | 6 | &nbsp;&nbsp;&nbsp;&nbsp;SHARED VOTING POWER<br>&nbsp;&nbsp;&nbsp;&nbsp;0 |
| NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | 7 | &nbsp;&nbsp;&nbsp;&nbsp;SOLE DISPOSITIVE POWER<br>&nbsp;&nbsp;&nbsp;&nbsp;1,885,533 |
| NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | NUMBER OF<br>SHARES<br> BENEFICIALLY <br>OWNED BY<br>EACH<br>REPORTING<br>PERSON<br>WITH: | 8 | &nbsp;&nbsp;&nbsp;&nbsp;SHARED DISPOSITIVE POWER<br>&nbsp;&nbsp;&nbsp;&nbsp;0 |
| &nbsp;&nbsp; 9 | &nbsp;&nbsp;&nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>&nbsp;&nbsp;&nbsp;&nbsp;1,885,533 | &nbsp;&nbsp;&nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>&nbsp;&nbsp;&nbsp;&nbsp;1,885,533 | &nbsp;&nbsp;&nbsp;&nbsp;AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>&nbsp;&nbsp;&nbsp;&nbsp;1,885,533 |
| &nbsp;&nbsp;10 | &nbsp;&nbsp;&nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)<br>☐ | &nbsp;&nbsp;&nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)<br>☐ | &nbsp;&nbsp;&nbsp;&nbsp;CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)<br>☐ |
| &nbsp;&nbsp;11 | &nbsp;&nbsp;&nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9<br>&nbsp;&nbsp;&nbsp;&nbsp;10.5%<sup>(1)</sup> | &nbsp;&nbsp;&nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9<br>&nbsp;&nbsp;&nbsp;&nbsp;10.5%<sup>(1)</sup> | &nbsp;&nbsp;&nbsp;&nbsp;PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9<br>&nbsp;&nbsp;&nbsp;&nbsp;10.5%<sup>(1)</sup> |
| &nbsp;&nbsp;12 | &nbsp;&nbsp;&nbsp;&nbsp;TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)<br>&nbsp;&nbsp;&nbsp;&nbsp;CO | &nbsp;&nbsp;&nbsp;&nbsp;TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)<br>&nbsp;&nbsp;&nbsp;&nbsp;CO | &nbsp;&nbsp;&nbsp;&nbsp;TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)<br>&nbsp;&nbsp;&nbsp;&nbsp;CO |

---

(1) &nbsp;&nbsp;&nbsp;&nbsp;This percentage is calculated based upon 17,945,995 shares of the Issuer's Common Stock outstanding as set forth in the Issuer's Form 10-Q for the third quarter ended September 30, 2022, filed with the Securities and Exchange Commission on November 2, 2022.

**Item 1(a).**&nbsp;&nbsp;&nbsp;&nbsp;Name of Issuer:<br>INmune Bio, Inc.

------

**Item 1(b).**&nbsp;&nbsp;&nbsp;&nbsp;Address of Issuer's Principal Executive Offices:<br>225 NE Mizner Blvd., Suite 640,<br>Boca Raton, FL 33432

**Item 2(a).**&nbsp;&nbsp;&nbsp;&nbsp;Name of Person Filing:<br>Xencor, Inc. (the "Reporting Person")

**Item 2(b).**&nbsp;&nbsp;&nbsp;&nbsp;Address of Principal Business Office or, if none, Residence:<br>The address of the principal business office of the Reporting Person is:<br>111 West Lemon Avenue<br>Monrovia, California 91016

**Item 2(c).**&nbsp;&nbsp;&nbsp;&nbsp;Citizenship:<br>The Reporting Person is a corporation organized under the laws of the State of Delaware.

**Item 2(d).**&nbsp;&nbsp;&nbsp;&nbsp;Title of Class of Securities:<br>Common Stock, par value $0.001 per share ("Common Stock")

**Item 2(e).**&nbsp;&nbsp;&nbsp;&nbsp;CUSIP Number:<br>45782T105

**Item 3.**&nbsp;&nbsp;&nbsp;&nbsp;**If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:**<br> Not applicable

**Item 4.**&nbsp;&nbsp;&nbsp;&nbsp;**Ownership<br>**<br> The Reporting Person directly holds 1,885,533 shares of Common Stock. The information required by this item with respect to the Reporting Person is set forth in Rows 5 through 9 and 11 of the cover page to this Schedule 13G/A.

**Item 5.**&nbsp;&nbsp;&nbsp;&nbsp;**Ownership of 5 Percent or Less of a Class**<br> If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ☐.

**Item 6.**&nbsp;&nbsp;&nbsp;&nbsp;**Ownership of More than 5 Percent on Behalf of Another Person:**<br> Not applicable

**Item 7.**&nbsp;&nbsp;&nbsp;&nbsp;**Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person:**<br> Not applicable

**Item 8.**&nbsp;&nbsp;&nbsp;&nbsp;**Identification and Classification of Members of the Group:**<br> Not applicable

**Item 9.**&nbsp;&nbsp;&nbsp;&nbsp;**Notice of Dissolution of a Group:**<br> Not applicable

**Item 10.**&nbsp;&nbsp;&nbsp;&nbsp;**Certifications:**<br> Not applicable

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**SIGNATURE**

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

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| | | |
|:---|:---|:---|
| Dated: February 15, 2023 |  |  |
|  | **XENCOR, INC.** | **XENCOR, INC.** |
|  | By: | /*s/ John J. Kuch* |
|  |  | John J. Kuch, |
|  |  | Senior Vice President and Chief Financial Officer |

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**ATTENTION:**

**Intentional misstatements or omissions of fact constitute Federal criminal violations (See 18 U.S.C. 1001)**

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