# EDGAR Filing Document

**Accession Number:** 0001965743
**File Stem:** 0001104659-25-114092
**Filing Date:** 2025-11
**Character Count:** 14611
**Document Hash:** c26ce6fcfdcdaa7dd0cdd90b72620692
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-114092.hdr.sgml**: 20251119

**ACCESSION NUMBER**: 0001104659-25-114092

**CONFORMED SUBMISSION TYPE**: SCHEDULE 13G

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20251119

**DATE AS OF CHANGE**: 20251119

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Orchestra BioMed Holdings, Inc.
- **CENTRAL INDEX KEY:** 0001814114
- **STANDARD INDUSTRIAL CLASSIFICATION:** SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-92240
- **FILM NUMBER:** 251499389

**BUSINESS ADDRESS:**
- **STREET 1:** 150 UNION SQUARE DRIVE
- **CITY:** NEW HOPE
- **STATE:** PA
- **ZIP:** 18938
- **BUSINESS PHONE:** 646-343-9298

**MAIL ADDRESS:**
- **STREET 1:** 150 UNION SQUARE DRIVE
- **CITY:** NEW HOPE
- **STATE:** PA
- **ZIP:** 18938

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Health Sciences Acquisitions Corp 2
- **DATE OF NAME CHANGE:** 20200603
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Tasso Partners, LLC
- **CENTRAL INDEX KEY:** 0001965743

**ORGANIZATION NAME:**
- **EIN:** 862809628
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G

**BUSINESS ADDRESS:**
- **STREET 1:** P.O. BOX 6194
- **CITY:** FAIR HAVEN
- **STATE:** NJ
- **ZIP:** 07704
- **BUSINESS PHONE:** 347-986-0729

**MAIL ADDRESS:**
- **STREET 1:** P.O. BOX 6194
- **CITY:** FAIR HAVEN
- **STATE:** NJ
- **ZIP:** 07704

## Exhibit 99.1

**EXHIBIT 1**

**JOINT FILING AGREEMENT**

**PURSUANT TO RULE 13d-1(k)**

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him or it contained herein and therein, but shall not be responsible for the completeness and accuracy of the information concerning the others, except to the extent that he or it knows or has reason to believe that such information is inaccurate. The undersigned hereby further agree that this Joint Filing Agreement may be executed in any number of counterparts, each of which when so executed shall be deemed to be an original, but all of which counterparts shall together constitute one and the same instrument.

Date: November 19, 2025

---

| | |
|:---|:---|
| Tasso Partners, LLC | Tasso Partners, LLC |
| By: | /s/ Dana Lorenzo |
| Name: | Dana Lorenzo |
| Title: | Manager of Tasso Capital, LLC, which controls Tasso Partners, LLC |

---

---

| | |
|:---|:---|
| Dana Lorenzo | Dana Lorenzo |
| By: | /s/ Dana Lorenzo |
| Name: | Dana Lorenzo |

---

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## SCHEDULE 13G

### Under the Securities Exchange Act of 1934

**Issuer:** Orchestra BioMed Holdings, Inc.

**Title of Class of Securities:** Common Stock, par value $0.0001 per share

**CUSIP Number:** 68572M106

**Date of Event Which Requires Filing of this Statement:** 11/15/2025

**Check the appropriate box to designate the rule pursuant to which this Schedule is filed:**

- [ ] Rule 13d-1(b)

- [x] Rule 13d-1(c)

- [ ] Rule 13d-1(d)

---

| 1. | Names of Reporting Persons<br>Tasso Partners, LLC | Names of Reporting Persons<br>Tasso Partners, LLC |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>2849592.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>2849592.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2849592.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2849592.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.0% | Percent of Class Represented by Amount in Row (9)<br>5.0% |
| 12. | Type of Reporting Person (See Instructions)<br>OO | Type of Reporting Person (See Instructions)<br>OO |

**Comment for Type of Reporting Person:** (1) Tasso Partners, LLC owns the shares of common stock of Orchestra BioMed Holdings, Inc. (the "Issuer"); Tasso Capital, LLC is the manager which controls Tasso Partners, LLC and Dana Lorenzo controls Tasso Capital, LLC. (2) Consists of 2,849,592 shares of common stock held by the Reporting Person, which are beneficially owned by Dana Lorenzo, which is the trustee of GCL Family Trust (the "Trust"), and included pursuant to Rule 13d-3(d)(1)(i) of the Securities Exchange Act of 1934, as amended. (3) The percentage ownership was calculated based on a denominator which is the sum of 56,846,755 shares of Common Stock that the Issuer has advised the Reporting Person were issued and outstanding as of the filing date of this report.

---

| 1. | Names of Reporting Persons<br>Dana Lorenzo | Names of Reporting Persons<br>Dana Lorenzo |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>X1 | Citizenship or Place of Organization<br>X1 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>249000.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>2849592.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>249000.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>2849592.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>3098592.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>3098592.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.5% | Percent of Class Represented by Amount in Row (9)<br>5.5% |
| 12. | Type of Reporting Person (See Instructions)<br>IN | Type of Reporting Person (See Instructions)<br>IN |

**Comment for Type of Reporting Person:** (1) Tasso Partners, LLC owns the shares of common stock Orchestra BioMed Holdings, Inc. (the "Issuer"); Tasso Capital, LLC is the manager which controls Tasso Partners, LLC and Dana Lorenzo controls Tasso Capital, LLC. (2) Shared voting and dispositive power consists of 2,849,592 shares of Common Stock held by the Reporting Person which are beneficially owned by Dana Lorenzo, which is the trustee of the Trust, and included pursuant to Rule 13d-3(d)(1)(i) of the Securities Exchange Act of 1934, as amended. (3) Sole voting and dispositive power consists of (i) 219,000 shares of Common Stock owned by the Trust, which are beneficially owned by Dana Lorenzo, the trustee of the Trust and (ii) 30,000 warrants exercisable within 60 days of November 19, 2025, into 30,000 shares of common stock. (4) Aggregate amount beneficially owned consists of (i) 2,849,592 shares of Common Stock held by the Reporting Person, (ii) 219,000 shares of Common Stock owned by the Trust, which are beneficially owned by Dana Lorenzo, the trustee of the Trust and (iii) 30,000 warrants exercisable within 60 days of November 19, 2025, into 30,000 shares of common stock, which are beneficially owned by Dana Lorenzo, the trustee of the Trust, and included pursuant to Rule 13d-3(d)(1)(i) of the Securities Exchange Act of 1934, as amended. (5) The percentage ownership was calculated based on a denominator which is the sum of 56,846,755 shares of Common Stock that the Issuer has advised the Reporting Person were issued and outstanding as of the filing date of this report.

---

**Item 1(a). Name of Issuer:**
Orchestra BioMed Holdings, Inc.

**Item 1(b). Address of Issuer's Principal Executive Offices:**
150 Union Square Drive New Hope, Pennsylvania, 18938

**Item 2(a). Name of Person Filing:**
This statement is filed on behalf of: (1) Tasso Partners, LLC; and (2) Dana Lorenzo. The foregoing persons are individually referred to as a "Reporting Person" and hereinafter collectively referred to as the "Reporting Persons". Any disclosures herein with respect to persons other than the Reporting Persons are made on information and belief after making inquiry to the appropriate party. The Reporting Persons have entered into a Joint Filing Agreement, a copy of which is filed as Exhibit 1 to this Schedule 13G, pursuant to which such Reporting Persons have agreed to file this Schedule 13G and all subsequent amendments to the Schedule 13G jointly in accordance with the provisions of Rule 13d-1(k) of the Act. The filing of this Schedule 13G should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of the shares of Common Stock reported herein.

**Item 2(b). Address of Principal Business Office:**
The principal business address of each of the Reporting Persons is: P.O. Box 503 Rumson, NJ 07760

**Item 2(c). Citizenship:**
Tasso Partners, LLC is a limited liability company organized under the laws of the State of Delaware. Dana Lorenzo is a citizen of the United States.

**Item 2(d). Title of Class of Securities:**
Common Stock, par value $0.0001 per share

**Item 2(e). CUSIP Number:**
68572M106

**Item 3. If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:**

(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d) [ ] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).

(e) [ ] An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);

(f) [ ] An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);

(g) [ ] A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j) [ ] A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), if filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:

(k) [ ] Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).

**Item 4. Ownership:**

**(a) Amount beneficially owned:**

Tasso Partners, LLC - 2,849,592 shares of common stock
Dana Lorenzo - 3,098,592 shares of common stock

**(b) Percent of class:**

Tasso Partners, LLC - 5.0%
Dana Lorenzo - 5.5%

**(c) Number of shares as to which the person has:**

**(i) Sole power to vote or to direct the vote:**

Tasso Partners, LLC - 0
Dana Lorenzo - 249,000

**(ii) Shared power to vote or to direct the vote:**

Tasso Partners, LLC - 2,849,592
Dana Lorenzo - 2,849,592

**(iii) Sole power to dispose or to direct the disposition of:**

Tasso Partners, LLC - 0
Dana Lorenzo - 249,000

**(iv) Shared power to dispose or to direct the disposition of:**

Tasso Partners, LLC - 2,849,592
Dana Lorenzo - 2,849,592

**Item 5. Ownership of Five Percent or Less of a Class.**

[x] If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following.

**Item 6. Ownership of More than 5 Percent on Behalf of Another Person.**

Not Applicable

**Item 7. Identification and Classification of the Subsidiary**

Not Applicable

**Item 8. Identification and Classification of Members of the Group**

Tasso Partners, LLC owns the Issuer shares; Tasso Capital, LLC is the manager which controls Tasso Partners, LLC and Dana Lorenzo is the trustee of the Trust and controls Tasso Capital, LLC.

**Item 9. Notice of Dissolution of Group**

Not Applicable

**Item 10. Certification:**

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

### SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Tasso Partners, LLC**

**Date:** 11/19/2025

**By:** /s/ Dana Lorenzo/Manager of Tasso Capital, LLC, which controls Tasso Partners, LLC

**Name & Title:** Dana Lorenzo/Manager of Tasso Capital, LLC, which controls Tasso Partners, LLC

**Dana Lorenzo**

**Date:** 11/19/2025

**By:** /s/ Dana Lorenzo

**Name & Title:** Dana Lorenzo