# EDGAR Filing Document

**Accession Number:** 0001840904
**File Stem:** 0001193125-25-243544
**Filing Date:** 2025-10
**Character Count:** 20205
**Document Hash:** f8fb3398dd978024fe79ff2d9d3f305a
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-243544.hdr.sgml**: 20251020

**ACCESSION NUMBER**: 0001193125-25-243544

**CONFORMED SUBMISSION TYPE**: SCHEDULE 13D/A

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20251020

**DATE AS OF CHANGE**: 20251020

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ATAI Life Sciences N.V.
- **CENTRAL INDEX KEY:** 0001840904
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** P7
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13D/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-93405
- **FILM NUMBER:** 251403795

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** PROF. J.H. BAVINCKLAAN 7
- **CITY:** AMSTELVEEN
- **PROVINCE COUNTRY:** P7
- **ZIP:** 1183
- **BUSINESS PHONE:** 49 89 2153 9035

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** PROF. J.H. BAVINCKLAAN 7
- **CITY:** AMSTELVEEN
- **PROVINCE COUNTRY:** P7
- **ZIP:** 1183

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ATAI Life Sciences B.V.
- **DATE OF NAME CHANGE:** 20210115
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Apeiron Investment Group Ltd.
- **CENTRAL INDEX KEY:** 0001845711

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** O1
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13D/A

**BUSINESS ADDRESS:**
- **STREET 1:** BLOCK A, APT.12
- **STREET 2:** IL-PIAZZETTA, TOWER ROAD
- **CITY:** SLIEMA
- **STATE:** O1
- **ZIP:** SLM1605
- **BUSINESS PHONE:** 44 7557 251 563

**MAIL ADDRESS:**
- **STREET 1:** BLOCK A, APT.12
- **STREET 2:** IL-PIAZZETTA, TOWER ROAD
- **CITY:** SLIEMA
- **STATE:** O1
- **ZIP:** SLM1605

### Attached PDF Documents

**Attachment 1:** `ck0000000000-ex99_1.pdf`

_No text found in this document._

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## SCHEDULE 13D

### Under the Securities Exchange Act of 1934

**(Amendment No. 3)**

**ATAI Life Sciences N.V.**

*(Name of Issuer)*

**Ordinary Shares, par value Euro 0.10 per share**

*(Title of Class of Securities)*

**45822R101**

*(CUSIP Number)*

**Evan S. Simpson**<br>1 New Fetter Lane<br>London X0 EC4A 1AN<br>44 20 7959-8426

*(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)*

**10/16/2025**

*(Date of Event Which Requires Filing of this Statement)*

| **CUSIP No.** | **45822R101** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Apeiron Investment Group Ltd.** | Name of reporting person<br>**Apeiron Investment Group Ltd.** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**WC** | Source of funds (See Instructions)<br>**WC** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**O1** | Citizenship or place of organization<br>**O1** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**55211716.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**55211716.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**55211716.00** | Aggregate amount beneficially owned by each reporting person<br>**55211716.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**23.4%** | Percent of class represented by amount in Row (11)<br>**23.4%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**CO** | Type of Reporting Person (See Instructions)<br>**CO** | |

---

| **CUSIP No.** | **45822R101** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Apeiron Presight Capital Fund II, L.P.** | Name of reporting person<br>**Apeiron Presight Capital Fund II, L.P.** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**AF** | Source of funds (See Instructions)<br>**AF** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**DELAWARE** | Citizenship or place of organization<br>**DELAWARE** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**1799302.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**1799302.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**1799302.00** | Aggregate amount beneficially owned by each reporting person<br>**1799302.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**0.8%** | Percent of class represented by amount in Row (11)<br>**0.8%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**PN** | Type of Reporting Person (See Instructions)<br>**PN** | |

---

| **CUSIP No.** | **45822R101** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Presight Capital Management I, L.L.C.** | Name of reporting person<br>**Presight Capital Management I, L.L.C.** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**—** | Source of funds (See Instructions)<br>**—** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**DELAWARE** | Citizenship or place of organization<br>**DELAWARE** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**1799302.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**1799302.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**1799302.00** | Aggregate amount beneficially owned by each reporting person<br>**1799302.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**0.8%** | Percent of class represented by amount in Row (11)<br>**0.8%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**OO** | Type of Reporting Person (See Instructions)<br>**OO** | |

---

| **CUSIP No.** | **45822R101** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Fabian Hansen** | Name of reporting person<br>**Fabian Hansen** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**—** | Source of funds (See Instructions)<br>**—** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**—** | Citizenship or place of organization<br>**—** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**1799302.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**1799302.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**1799302.00** | Aggregate amount beneficially owned by each reporting person<br>**1799302.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**0.8%** | Percent of class represented by amount in Row (11)<br>**0.8%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**IN** | Type of Reporting Person (See Instructions)<br>**IN** | |

---

| **CUSIP No.** | **45822R101** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Christian Angermayer** | Name of reporting person<br>**Christian Angermayer** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**—** | Source of funds (See Instructions)<br>**—** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**—** | Citizenship or place of organization<br>**—** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**1339663.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**55211716.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**1339663.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**55211716.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**56551379.00** | Aggregate amount beneficially owned by each reporting person<br>**56551379.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**24.0%** | Percent of class represented by amount in Row (11)<br>**24.0%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**IN** | Type of Reporting Person (See Instructions)<br>**IN** | |

---

**Item 1. Security and Issuer**

**(a) Title of Class of Securities:**
Ordinary Shares, par value Euro 0.10 per share

**(b) Name of Issuer:**
ATAI Life Sciences N.V.

**(c) Address of Issuer's Principal Executive Offices:**
Wallstrasse 16, Berlin, 2M, 100179

**Item 5. Interest in Securities of the Issuer**

**(a)**
As of October 20, 2025, the Reporting Persons collectively beneficially own 55,211,716 Ordinary Shares, representing approximately 23.4% of the voting rights attached to the Ordinary Shares.

The ownership percentages set forth in this Amendment No. 3 have been calculated on the basis of 235,969,597 Ordinary Shares outstanding as of October 16, 2025, as reported in the Issuer's Prospectus filed pursuant to Rule 424(b)(5) with the Securities and Exchange Commission ("SEC") on October 17, 2025, an additional 2,367,200 Ordinary Shares issued to Apeiron upon the conversion of the previously disclosed convertible promissory notes of the Issuer, and 1,339,663 vested options that are exercisable into one Ordinary share each at an exercise price of $5.68 per Ordinary Share held by Christian Angermayer as of October 16, 2025 (the "Vested Options").

**(b)**
The following table sets forth, as of the date of this Amendment No. 3, the aggregate number of Ordinary Shares and percentage of Ordinary Shares beneficially owned by each of the Reporting Persons, as well as the number of Ordinary Shares as to which each Reporting Person has the sole power to vote or to direct the vote, shared power to vote or to direct the vote, sole power to dispose or to direct the disposition of, or shared power to dispose or to direct thedisposition of.

                                                                                                    Sole               Shared             Sole power to   Shared
                                                                                                    power            power              dispose              power
                                                        Amount           Percent       to vote or      to vote or to       or to direct          to dispose or
                                                        beneficially      of class        to direct       direct the            the                    to direct the
Reporting Person                            owned	                             the vote         vote                 disposition      disposition
Apeiron Investment Group,
Ltd.                                                   55,211,716    23.4%            0                 55,211,716        0                       55,211,716
Apeiron Presight Capital Fund
II, L.P.	                                         1,799,302       0.8%           0                    1,799,302        0                        1,799,302
Presight Capital Management
I, L.L.C.	                                         1,799,302       0.8%            0                    1,799,302        0                        1,799,302
Fabian Hansen
	                                                 1,799,302       0.8%            0                    1,799,302        0                        1,799,302
Christian Angermayer
                                                          56,551,379   24.0%           1,339,663       55,211,716    1,339,663         55,211,716

Presight II is the record holder of 1,799,302 Ordinary Shares. Apeiron is the record holder of 53,412,414 Ordinary Shares which includes 2,367,200 Ordinary Shares issued to Apeiron upon the conversion of the previously disclosed convertible promissory notes of the Issuer. Christian Angermayer may be deemed to beneficially own 1,339,663 Ordinary Shares underlying the Vested Options.

Presight Management is the general partner of Presight II. Apeiron and Fabian Hansen are the managing members of Presight Management. Christian Angermayer is the controlling shareholder of Apeiron.

As a result, each of Presight Management, Apeiron, Mr. Hansen and Mr. Angermayer may be deemed to share beneficial ownership of the securities held by Presight II, and Mr. Angermayer may be deemed to share beneficial ownership of the securities held by Apeiron.

**(c)**
Except as described in this Item 5, none of the Reporting Persons has beneficial ownership of any Ordinary Shares or, except as described in this Schedule 13D, has effected any transaction in the Ordinary Shares during the past 60 days.

**Item 6. Contracts, Arrangements, Understandings or Relationships With Respect to Securities of the Issuer.**

Item 6 of the Schedule 13D is hereby amended and supplemented by the addition of the following:

Lock-Up Agreement

On October 20, 2025, the Issuer closed a registered offering of 23,725,000 Common Shares at a purchase price of $5.48 per share with gross proceeds of approximately $130 million (the "Offering"). On October 16, 2025, Apeiron entered into a lock-up agreement (the "Lock-Up Agreement") with Jefferies LLC, as underwriter of the Offering. Pursuant to the terms of the form of Lock-Up Agreement, Apeiron has agreed that, for a period ending 90 days after the date of pricing of the Offering, it will not, without the prior written consent of the underwriter of the Offering and subject to certain customary exceptions, not to offer, pledge, sell, contract to sell, sell any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase, lend, or otherwise transfer or dispose of, directly or indirectly, any of the Issuer's Ordinary Shares or securities convertible into or exchangeable or exercisable for any of the Issuer's Ordinary Shares (provided, however, that the Lock-Up Agreement shall not apply to transfers of Ordinary Shares acquired in the open market after the completion of the Offering).

The foregoing description of the Lock-Up Agreement does not purport to be complete and is qualified in its entirety by the full text of such agreement, which is attached hereto as Exhibit 99.1 and incorporated herein by reference.

Other than as described herein, there are no contracts, arrangements, understandings or relationships among the Reporting Persons, or between the Reporting Persons and any other person, with respect to the securities of the Issuer.

### SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Apeiron Investment Group Ltd.

**Signature:** /s/ Mario Frendo

**Name/Title:** Mario Frendo, Director

**Date:** 10/20/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Apeiron Presight Capital Fund II, L.P.

**Signature:** /s/ Fabian Hansen

**Name/Title:** Fabian Hansen, Managing Member

**Date:** 10/20/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Presight Capital Management I, L.L.C.

**Signature:** /s/ Fabian Hansen

**Name/Title:** Fabian Hansen, Managing Member

**Date:** 10/20/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Fabian Hansen

**Signature:** /s/ Fabian Hansen

**Name/Title:** Fabian Hansen

**Date:** 10/20/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Christian Angermayer

**Signature:** /s/ Christian Angermayer

**Name/Title:** Christian Angermayer

**Date:** 10/20/2025