# EDGAR Filing Document

**Accession Number:** 0001095435
**File Stem:** 0001171843-25-004719
**Filing Date:** 2025-7
**Character Count:** 17616
**Document Hash:** 15c2fc4b1b3aa70ff30518b14bca0c2f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001171843-25-004719.hdr.sgml**: 20250725

**ACCESSION NUMBER**: 0001171843-25-004719

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250725

**FILED AS OF DATE**: 20250725

**DATE AS OF CHANGE**: 20250725

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PORTAGE BIOTECH INC.
- **CENTRAL INDEX KEY:** 0001095435
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** D8
- **FISCAL YEAR END:** 0331

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-40086
- **FILM NUMBER:** 251151965

**BUSINESS ADDRESS:**
- **STREET 1:** CLARENCE THOMAS BUILDING
- **STREET 2:** P.O. BOX 4649, ROAD TOWN
- **CITY:** TORTOLA
- **STATE:** D8
- **ZIP:** VG1110
- **BUSINESS PHONE:** 416-737-7600

**MAIL ADDRESS:**
- **STREET 1:** CLARENCE THOMAS BUILDING
- **STREET 2:** P.O. BOX 4649, ROAD TOWN
- **CITY:** TORTOLA
- **STATE:** D8
- **ZIP:** VG1110

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** BONTAN CORP INC
- **DATE OF NAME CHANGE:** 20030421

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** DEALCHECK COM INC
- **DATE OF NAME CHANGE:** 19990921

---

| |
|:---|
| **UNITED STATES** |
| **SECURITIES AND EXCHANGE COMMISSION** |
| **Washington, D.C. 20549** |
| **FORM 6-K** |
| **REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16** |
| **UNDER THE SECURITIES EXCHANGE ACT OF 1934** |
| **For the month of July 2025** |
| Commission File Number: **001-40086** |
| **PORTAGE BIOTECH INC.** |
| (Translation of registrant's name into English) |
| **Clarence Thomas Building, P.O. Box 4649, Road Town, Tortola, British Virgin Islands, VG1110** |
| (Address of principal executive office) |

---

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F. <br> <br> Form 20-F [ X ] Form 40-F [ ]

**INCORPORATION BY REFERENCE**

This report on Form 6-K (including any exhibits attached hereto) shall be deemed to be incorporated by reference into the registration statement on Form S-8 (File No. 333-275842) and Form F-3, as amended (File No. 333-286961) of Portage Biotech Inc. (including any prospectuses forming a part of such registration statement) and to be a part thereof from the date on which this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished.

**EXHIBITS**

---

| | |
|:---|:---|
| **<u>Exhibit No.</u>** | **<u>Description</u>** |
| [99.1\*](exh_991.htm) | [Press Release dated July 25, 2025](exh_991.htm) |
| _______ |  |
| \* Filed herewith | \* Filed herewith |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: July 25, 2025

**PORTAGE BIOTECH INC.**

---

| | |
|:---|:---|
| By: | */s/ Andrea Park* |
|  | Andrea Park |
|  | Chief Financial Officer |

---

## Exhibit 99.1

**EXHIBIT 99.1**

**Portage Biotech Reports Results for Fiscal Year Ended March 31, 2025**

DOVER, Del., July 25, 2025 (GLOBE NEWSWIRE) -- Portage Biotech Inc. ("Portage" or the "Company") (NASDAQ: PRTG), a clinical-stage immuno-oncology company formed under the laws of the British Virgin Islands, with a portfolio of novel multi-targeted therapies for use as monotherapy and in combination, today reported its financial results for the fiscal year ended March 31, 2025.

**Financial Results from Year Ended March 31, 2025**

The Company incurred a net loss of approximately $6.8 million during the fiscal year ended March 31, 2025 ("Fiscal 2025"), which includes approximately $0.2 million of net non-cash expenses. This compares to a net loss of approximately $75.4 million during the fiscal year ended March 31, 2024 ("Fiscal 2024"), which included approximately $60.9 million of net non-cash expenses. Net loss decreased by approximately $68.6 million year-over-year, which is primarily due to lower non-cash losses attributable to full impairment of the Company's identifiable intangible assets, goodwill, and certain investments as of March 31, 2024.

Operating expenses, including research and development ("R&D") costs and general and administrative ("G&A") expenses, were $7.4 million in the Fiscal 2025, down from $18.2 million in the Fiscal 2024, a decrease of $10.8 million, as detailed below.

R&D expenses decreased by approximately $9.4 million, or approximately 75%, from approximately $12.5 million in Fiscal 2024, to approximately $3.1 million in Fiscal 2025. The decrease was primarily attributable to clinical trial costs (principally CRO-related), which decreased by approximately $3.4 million, from $5.2 million in Fiscal 2024 to $1.8 million in Fiscal 2025, due to the decision to pause enrollment in our sponsored clinical trials in the third and fourth quarters of Fiscal 2024. Manufacturing-related costs decreased by $1.6 million from $1.8 million in Fiscal 2024, compared to $0.2 million in Fiscal 2025, related to the iNKT and adenosine clinical trials. During Fiscal 2024, we deprioritized development of the iNKT program and closed the related clinical trial. In August 2024, we temporarily paused enrollment in the PORT-6 arm of the study. Enrollment resumed in March 2025 with the initiation of the final dose escalation cohort. Non-cash share-based compensation expense allocable to R&D decreased by $1.4 million, from $1.4 million in Fiscal 2024, compared to nil in Fiscal 2025, as the relevant share options fully vested by Fiscal 2024 and no new share option awards were allocable to R&D during Fiscal 2025. Payroll-related expenses decreased by $0.9 million from $1.6 million in Fiscal 2024 to $0.7 million in Fiscal 2025; the decrease in salaries is primarily due to reduced headcount. R&D services decreased by $0.5 million due to the pause of medical writing, analysis, and clinical studies at the beginning of Fiscal 2025. Scientific consulting fees decreased by approximately $0.6 million from $0.8 million in Fiscal 2024 to $0.2 million in Fiscal 2025 to reflect the decrease in activity year-over-year. Additionally, in Fiscal 2024, we incurred a one-time milestone payment of $0.5 million for dosing our first adenosine patients, and finally, $0.5 million in fees paid with respect to the transition of the iNKT study prior to discontinuing the study in Fiscal 2024.

G&A expenses decreased by approximately $1.4 million, or approximately 24.9%, from approximately $5.7 million in Fiscal 2024, to approximately $4.3 million in Fiscal 2025. The decreases are attributable to decreases in: non-cash share-based compensation expense allocable to G&A expenses by $0.9 million, from $1.2 million in Fiscal 2024 to $0.3 million in Fiscal 2025, primarily due to the vesting of certain share options granted in prior years fully vesting by Fiscal 2024 and lower fair value associated with more recent grants; professional fees by $0.7 million, from $2.3 million in Fiscal 2024, compared to $1.6 million in Fiscal 2025, primarily due to decline in public relations and accounting services related expenses; directors' fees by $0.1 million, from $0.3 million in Fiscal 2024, compared to $0.2 million Fiscal 2025 due to the adoption of a new director compensation policy in March 2025; and general office related supplies and expenses by $0.1 million, from $0.2 million in Fiscal 2024, compared to $0.1 million in Fiscal 2025. These decreases were offset to some extent by an increase in payroll-related and consulting expenses by $0.4 million from $0.9 million in Fiscal 2024 to $1.3 million in Fiscal 2025 primarily attributable to $0.2 million in retention payments to an employee and a consultant included in payroll expenses allocable to general and administrative expenses.

The primary reasons for the year-over-year differences in the Company's pre-tax items of income and expense were substantially non-cash in nature, aggregating approximately $0.6 million net gain in Fiscal 2025 compared to approximately $67.7 million net loss in Fiscal 2024. The net gain in year over year were attributable to $0.9 million net gain from the settlement and release of obligations and liabilities under the Master Services Agreement between iOx and Parexel partially offset to some extent by the $0.4 million non-cash loss from the change in the fair value of certain warrants accounted for as liabilities, issued in connection with a private placement offering in October 2023 in Fiscal 2025. In Fiscal 2024, the recognized full impairment of the carrying value of in-process research and development of $57.9 million for iOx and $23.6 million for Tarus, as well as a $1.0 million loss on the impairment of the Company's investment in Stimunity and the Stimunity convertible note. These expenses were partially offset by the non-cash gains from the decrease in the fair value of the deferred purchase price payable to the former Tarus shareholders and the deferred obligation for the iOx milestone, totaling $11.3 million. These losses were offset to some extent by a $0.7 million gain on the sale of Intensity shares, accounted for under fair value through other comprehensive income (FVOCI), which had a carrying value of $2.1 million and a $2.4 million loss during Fiscal 2024 from the Company's equity financing in October 2023, representing the excess of the fair value of certain warrants over the net proceeds. Additionally, a $6.9 million non-cash gain was recognized from the change in the fair value of certain warrants accounted for as liabilities issued in connection with this equity offering.

Additionally, the Company recognized a non-cash net deferred income tax benefit of $10.5 million in Fiscal 2024, compared to a non-cash net deferred income tax benefit of $3 thousand in Fiscal 2025. The benefit in Fiscal 2024 was primarily attributable to the tax effect of the non-cash impairment loss on IPR&D for iOx, partially offset by the derecognition of previously recognized losses.

As of March 31, 2025, the Company had cash and cash equivalents of approximately $1.7 million and total current liabilities of approximately $1.1 million.

**About Portage Biotech**

Portage Biotech is a clinical-stage immuno-oncology company advancing a pipeline of novel biologics to transform the immune system's ability to fight cancer. For more information, visit **www.portagebiotech.com**.

**Forward-Looking Statements**

All statements in this news release, other than statements of historical facts, including without limitation, statements regarding the Company's business strategy, plans and objectives of management for future operations and those statements preceded by, followed by or that otherwise include the words "believe," "expects," "anticipates," "intends," "estimates," "will," "may," "plans," "potential," "continues," or similar expressions or variations on such expressions are forward-looking statements. As a result, forward-looking statements are subject to certain risks and uncertainties, including, but not limited to: the risk that the Company may not secure financing, the uncertainty of the Company's ability to continue as a going concern, scientific results may not be as expected, and other factors set forth in "Item 3 - Key Information-Risk Factors" in the Company's Annual Report on Form 20-F for the year ended March 31, 2025. Although the Company believes that the expectations reflected in these forward-looking statements are reasonable, undue reliance should not be placed on them as actual results may differ materially from these forward-looking statements. The forward-looking statements contained in this news release are made as of the date hereof, and the Company undertakes no obligation to update publicly or revise any forward-looking statements or information, except as required by law.

FOR MORE INFORMATION, PLEASE CONTACT:

Investor Relations:

ir@portagebiotech.com

Media Relations:

media@portagebiotech.com

---

tables to follow---

---

| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;**PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Operations and Other Comprehensive Loss**<br>**(U.S. Dollars in thousands, except per share amounts)** | &nbsp;&nbsp;**PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Operations and Other Comprehensive Loss**<br>**(U.S. Dollars in thousands, except per share amounts)** | &nbsp;&nbsp;**PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Operations and Other Comprehensive Loss**<br>**(U.S. Dollars in thousands, except per share amounts)** | &nbsp;&nbsp;**PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Operations and Other Comprehensive Loss**<br>**(U.S. Dollars in thousands, except per share amounts)** |
|  | **Years Ended March 31,** | **Years Ended March 31,** | **Years Ended March 31,** |
|  | **2025** | 2024 | 2023 |
| **Expenses** |  |  |  |
| &nbsp;&nbsp;Research and development | $**3129** | $12535 | $8674 |
| &nbsp;&nbsp;General and administrative expenses | **4254** | 5664 | 7901 |
| **Loss from operations** | **(7383)** | (18199) | (16575) |
| &nbsp;&nbsp;Change in fair value of warrant liability | **(388)** | 6868 | 33 |
| &nbsp;&nbsp;Change in fair value of deferred purchase price payable - Tarus and deferred obligation - iOx milestone | **-** | 11305 | 2711 |
| &nbsp;&nbsp;Gain on settlement with Parexel – iOx CRO | **946** |  |  |
| &nbsp;&nbsp;Loss on Registered Direct Offering | **-** | (2432) |  |
| &nbsp;&nbsp;Offering costs | **-** | (662) |  |
| &nbsp;&nbsp;Impairment loss - iOx IPR&D | **-** | (57890) | (59320) |
| &nbsp;&nbsp;Impairment loss - Tarus IPR&D | **-** | (23615) | (4585) |
| &nbsp;&nbsp;Impairment loss - Goodwill | **-** |  | (43862) |
| &nbsp;&nbsp;Impairment loss - Stimunity | **-** | (1002) | (818) |
| &nbsp;&nbsp;Impairment loss - Saugatuck | **-** | (178) |  |
| &nbsp;&nbsp;Commitment fee under Committed Purchase Agreement | **-** | (839) |  |
| &nbsp;&nbsp;Share of loss in associate accounted for using equity method | **-** | (233) | (260) |
| &nbsp;&nbsp;Gain on dissolution of investment in associate | **-** | 27 |  |
| &nbsp;&nbsp;Gain from sale of investment in public company | **-** | 725 |  |
| &nbsp;&nbsp;Foreign exchange transaction gain (loss) | **(7)** | 7 | (53) |
| &nbsp;&nbsp;Depreciation expense | **(35)** | (54) | (1) |
| &nbsp;&nbsp;Interest income | **89** | 274 | 217 |
| &nbsp;&nbsp;Interest expense | **(3)** | (32) | (9) |
| **Loss before provision for income taxes** | **(6781)** | (85930) | (122522) |
| &nbsp;&nbsp;Income tax benefit | **3** | 10548 | 17856 |
| **Net loss** | **(6778)** | (75382) | (104666) |
| **Other comprehensive loss** |  |  |  |
| &nbsp;&nbsp;Net unrealized loss on investments | **-** | (38) | (5283) |
| **Total comprehensive loss for year** | $**(6778)** | $(75420) | $(109949) |
| **<br>Net loss attributable to:** |  |  |  |
| &nbsp;&nbsp;**Owners of the Company**  | $**(6767)** | $(75339) | $(104611) |
| &nbsp;&nbsp;**Non-controlling interest** | **(11)** | (43) | (55) |
| **Net loss** | $**(6778)** | $(75382) | $(104666) |
| **<br>Comprehensive loss attributable to:** |  |  |  |
| &nbsp;&nbsp;**Owners of the Company** | $**(6767)** | $(75377) | $(109894) |
| &nbsp;&nbsp;**Non-controlling interest** | **(11)** | (43) | (55) |
| **Total comprehensive loss for year** | $**(6778)** | $(75420) | $(109949) |
| **Loss per share** |  |  |  |
| &nbsp;&nbsp;**Basic and diluted** | $**(5.72)** | $(77.83) | $(129.79) |
| **Weighted average shares outstanding Basic and diluted** | **1183** | 968 | 806 |

---

---

| | | |
|:---|:---|:---|
| **PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Financial Position**<br>**(U.S. Dollars in thousands)** | **PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Financial Position**<br>**(U.S. Dollars in thousands)** | **PORTAGE BIOTECH INC.**<br>**Consolidated Statements of Financial Position**<br>**(U.S. Dollars in thousands)** |
|  | **March 31,** | **March 31,** |
|  | **2025** | **2024** |
| **Assets** |  |  |
| **Current assets** |  |  |
| Cash and cash equivalents | $**1670** | $5028 |
| Prepaid expenses and other receivables | **555** | 2667 |
| **Total current assets** | **2225** | 7695 |
| **Non-current assets** |  |  |
| Right-of-use asset | **-** | 35 |
| &nbsp;&nbsp;Other assets, including equipment, net | **-** | 49 |
| **Total non-current assets** | **-** | 84 |
| **Total assets** | $**2225** | $7779 |
| **Liabilities and Equity (Deficit)** |  |  |
| **Current liabilities** |  |  |
| Accounts payable and accrued liabilities | $**1100** | $2836 |
| Lease liability - current, including interest | **-** | 40 |
| Other current liabilities | **-** | 3 |
| **Total current liabilities** | **1100** | 2879 |
| **Non-current liabilities** |  |  |
| Lease liability - non-current | **-** | 7 |
| Warrant liability | **1952** | 1564 |
| **Total non-current liabilities** | **1952** | 1571 |
| **Total liabilities** | **3052** | 4450 |
| **Shareholders' Equity (Deficit)** |  |  |
| &nbsp;&nbsp;Capital stock | **221800** | 219499 |
| &nbsp;&nbsp;Share option reserve | **23530** | 23841 |
| &nbsp;&nbsp;Accumulated deficit | **(245453)** | (239318) |
| **Total equity (deficit) attributable to owners of the Company** | **(123)** | 4022 |
| **Non-controlling interest** | **(704)** | (693) |
| **Total equity (deficit)** | **(827)** | 3329 |
| **Total liabilities and equity (deficit)** | $**2225** | $7779 |

---