# EDGAR Filing Document

**Accession Number:** 0001321732
**File Stem:** 0001321732-25-000097
**Filing Date:** 2025-7
**Character Count:** 34915
**Document Hash:** 6f9829b1f46773547baac2ac98d0801c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001321732-25-000097.hdr.sgml**: 20250729

**ACCESSION NUMBER**: 0001321732-25-000097

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 14

**CONFORMED PERIOD OF REPORT**: 20250729

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20250729

**DATE AS OF CHANGE**: 20250729

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Penumbra Inc
- **CENTRAL INDEX KEY:** 0001321732
- **STANDARD INDUSTRIAL CLASSIFICATION:** SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-37557
- **FILM NUMBER:** 251162042

**BUSINESS ADDRESS:**
- **STREET 1:** ONE PENUMBRA PLACE
- **CITY:** ALAMEDA
- **STATE:** CA
- **ZIP:** 94502
- **BUSINESS PHONE:** (510) 995-2486

**MAIL ADDRESS:**
- **STREET 1:** ONE PENUMBRA PLACE
- **CITY:** ALAMEDA
- **STATE:** CA
- **ZIP:** 94502

?xml version='1.0' encoding='ASCII'? pen-20250729

**__________________________________________________________________________________________________________________________**

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**_______________________________________________________________________________________________________________________________**

**FORM 8-K** 

**_______________________________________________________________________________________________________________________________**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of the**

**Securities Exchange Act of 1934**

**July 29, 2025**

**Date of Report (Date of earliest event reported)** 

**_______________________________________________________________________________________________________________________________**

**Penumbra, Inc.**

**(Exact name of registrant as specified in its charter)**

_______________________________________________________________________________________________________________________________

---

| | | |
|:---|:---|:---|
| **Delaware** | **001-37557** | **05-0605598** |
| **(State or other jurisdiction of incorporation or organization)** | **(Commission File No.)** | **(I.R.S. employer identification number)** |

---

**One Penumbra Place**

**Alameda, CA 94502**

**(Address of principal executive offices, including zip code)**

**(510) 748-3200**

**(Registrant's telephone number, including area code)** 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligations of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| **<u>Title of each class</u>** | **<u>Trading Symbol</u>** | **<u>Name of each exchange on which registered</u>** |
| Common Stock, Par value $0.001 per share | PEN | The New York Stock Exchange |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. □

**_______________________________________________________________________________________________________________________________**

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**_______________________________________________________________________________________________________________________________**

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| | |
|:---|:---|
| **Item 2.02.** | **Results of Operations and Financial Condition.** |

---

On July 29, 2025, Penumbra, Inc. issued a press release announcing financial results for the second fiscal quarter ended June 30, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

The information furnished on this Current Report on Form 8-K, including the attached exhibit, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference into any other filing under the Securities Act of 1933, as amended, or the Exchange Act, regardless of any general incorporation language in such a filing, except as expressly set forth by specific reference in such a filing.

---

| | |
|:---|:---|
| **Item 9.01.** | **Financial Statements and Exhibits.** |

---

(d) Exhibits.

---

| | |
|:---|:---|
| <u>Exhibit Number</u> | <u>Description</u> |
| <u>[99.1](pen-63025xexhibit991.htm)</u> | Press release of Penumbra, Inc. dated July 29, 2025. |
| 104 | Cover Page Interactive Data File (formatted as Inline Extensible Business Reporting Language). |

---

------

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
| | **Penumbra, Inc.** | **Penumbra, Inc.** |
| Date: July 29, 2025 | By: | /s/ Maggie Yuen |
|  |  | Maggie Yuen |
|  |  | Chief Financial Officer |

---

## Exhibit 99.1

**<u>Exhibit 99.1</u>**

![image1a.jpg](image1a.jpg)

**Penumbra, Inc. Reports Second Quarter 2025 Financial Results**

ALAMEDA, Calif., July 29, 2025 /PRNewswire/ -- Penumbra, Inc. (NYSE: PEN), the world's leading thrombectomy company, today reported financial results for the second quarter ended June 30, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**• Revenue of $339.5 million in the second quarter of 2025, an increase of 13.4% or 12.7% in constant currency**<sup>1</sup>**, compared to the second quarter of 2024.**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**• U.S. Thrombectomy revenue of $188.5 million in the second quarter of 2025, an increase of 22.6% compared to the second quarter of 2024. U.S. VTE revenue increased 42% compared to the same period a year ago.** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**• Income from operations of $40.8 million or operating margin of 12.0% in the second quarter of 2025.**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**• Net income of $45.3 million and adjusted EBITDA**<sup>1</sup> **of $61.4 million or net income margin of 13.3% and adjusted EBITDA margin**<sup>1</sup> **of 18.1% in the second quarter of 2025.**

**Second Quarter 2025 Financial Results**

Total revenue increased to $339.5 million for the second quarter of 2025 compared to $299.4 million for the second quarter of 2024, an increase of 13.4%, or 12.7% in constant currency<sup>1</sup>. The United States represented 76.8% of total revenue and international represented 23.2% of total revenue for the second quarter of 2025. Revenue from the U.S. increased 19.5% while revenue from our international regions decreased 3.2%, or 5.8% in constant currency<sup>1</sup>. Revenue from sales of our global thrombectomy products grew to $230.3 million in the second quarter of 2025, an increase of 13.1%, or 12.6% in constant currency<sup>1</sup> over the same period a year ago, driven primarily by the sales of our U.S. thrombectomy products which increased by 22.6% over the same period a year ago. Revenue from sales of our global embolization and access products grew to $109.2 million for the second quarter of 2025, an increase of 13.9%, or 12.8% in constant currency<sup>1</sup> from the same period a year ago, driven primarily by our U.S. embolization and access products which increased by 12.2% from the same period a year ago.

Gross profit for the second quarter of 2025 was $224.0 million, or 66.0% of total revenue compared to $162.8 million, or 54.4% of total revenue, for the second quarter of 2024, which included a one-time $33.4 million inventory impairment charge to cost of revenue in connection with the impairment of our immersive healthcare asset group. The impact of the one-time $33.4 million charge decreased our gross margin by 11.1 percentage points during the second quarter of 2024. Excluding the one-time inventory impairment charge, the improvement in gross margin was primarily driven by favorable product mix across our regions and productivity improvements. Gross margin is impacted by product mix, regional mix, and production initiatives to support demand and create future efficiencies. As such, with favorable product mix, improvement in productivity, and by leveraging our fixed costs on higher volume of new product sales during the year, our gross margin may be positively impacted in the future. As we move into the second half of 2025, we expect to see sequential gross margin expansion from favorable product mix and productivity improvements.

Total operating expenses and non-GAAP operating expenses<sup>1</sup> were $183.2 million, or 54.0% of total revenue for the second quarter of 2025. This compares to total operating expenses of $243.8 million, or 81.4% of total revenue for the second quarter of 2024, which included a $76.9 million long-lived assets impairment charge associated with the impairment of assets related to our immersive healthcare business during the second quarter of 2024 and a $2.4 million amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition. Excluding the charges noted above, total non-GAAP operating expenses<sup>1</sup> were $164.5 million, or 54.9% of total revenue for the second quarter of 2024. R&D expenses were $23.2 million for the second quarter of 2025, compared to $24.9 million for the second quarter of 2024. SG&A expenses were $160.0 million for the second quarter of 2025, compared to $141.9 million for the second quarter of 2024.

Income from operations and non-GAAP income from operations<sup>1</sup> was $40.8 million for the second quarter of 2025, compared to a loss from operations of $81.0 million for the second quarter of 2024. Excluding a $76.9 million long-lived assets impairment charge associated with the impairment of assets related to our immersive healthcare business during the second quarter of 2024 and a $2.4 million amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition, non-GAAP loss from operations<sup>1</sup> was $1.6 million for the second quarter of 2024.

**Updated Full Year 2025 Financial Outlook**

<sup>1</sup>See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

------

The Company is increasing its guidance for 2025 total revenue to a range of $1 billion, 355 million to $1 billion, 370 million, which represents 13% to 15% growth over 2024 revenue of $1 billion, 195 million. The Company maintains guidance for U.S. Thrombectomy growth of 20% to 21% compared to 2024 levels. The Company also maintains guidance for both gross margin and operating margin for full year 2025.

**Webcast and Conference Call Information**

Penumbra, Inc. will host a conference call to discuss the second quarter 2025 financial results after market close on Tuesday, July 29, 2025 at 4:30 PM Eastern Time. The conference call can be accessed live over the phone by dialing (888) 596-4144 (conference id: 6572573), or the webcast can be accessed on the "Events and Presentations" section under the "Investors" tab of the Company's website at: <u>www.penumbrainc.com</u>. The webcast will be available on the Company's website for at least two weeks following the completion of the call.

**About Penumbra**

Penumbra, Inc., the world's leading thrombectomy company, is focused on developing the most innovative technologies for challenging medical conditions such as ischemic stroke, venous thromboembolism such as pulmonary embolism, and acute limb ischemia. Our broad portfolio, which includes computer assisted vacuum thrombectomy (CAVT), centers on removing blood clots from head-to-toe with speed, safety and simplicity. By pioneering these innovations, we support healthcare providers, hospitals and clinics in more than 100 countries, working to improve patient outcomes and quality of life. For more information, visit <u>www.penumbrainc.com</u> and connect on <u>Instagram, LinkedIn, and X</u>.

**Non-GAAP Financial Measures**

In addition to financial measures prepared in accordance with U.S. generally accepted accounting principles ("GAAP"), the Company uses the following non-GAAP financial measures in this press release: a) constant currency, b) non-GAAP operating expenses, non-GAAP income (loss) from operations, non-GAAP net income (loss), and non-GAAP diluted earnings per share ("EPS") and c) adjusted EBITDA and adjusted EBITDA margin.

*Constant Currency*. The Company's constant currency revenue disclosures estimate the impact of changes in foreign currency rates on the translation of the Company's current period revenue as compared to the applicable comparable period in the prior year. This impact is derived by taking the current local currency revenue and translating it into U.S. dollars based upon the foreign currency exchange rates used to translate the local currency revenue for the applicable comparable period in the prior year, rather than the actual exchange rates in effect during the current period. It does not include any other effect of changes in foreign currency rates on the Company's results or business.

*Non-GAAP operating expenses, non-GAAP income (loss) from operations, non-GAAP net income (loss), and non-GAAP diluted EPS.* The adjustments to the GAAP financial measures reflect the exclusion of:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the effect of the amortization of finite lived intangible assets acquired in connection with the Sixense acquisition over their estimated useful lives;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the excess tax benefits associated with share-based compensation arrangements;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• non-recurring litigation related expenses; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• non-cash long-lived asset impairment charges related to the impairment of our immersive healthcare asset group.

*Adjusted EBITDA and adjusted EBITDA margin.* The Company's adjusted EBITDA reflects the exclusion from GAAP net income (loss) of:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• non-cash operating charges such as stock-based compensation, depreciation and amortization, and impairment charges;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• non-operating items such as interest income, interest expense, and provision for (benefit from) income taxes; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• non-recurring litigation related expenses.

Full reconciliation of these non-GAAP measures to the most comparable GAAP measures is set forth in the tables below.

Our management believes the non-GAAP financial measures disclosed in this press release are useful to investors in assessing the operating performance of our business and provide meaningful comparisons to prior periods and thus a more complete understanding of our business than could be obtained absent this disclosure. Specifically, we consider the change in constant currency revenue as a useful metric as it provides an alternative framework for assessing how our underlying business performed excluding the effect of foreign currency rate fluctuations. We consider non-GAAP operating expenses, non-GAAP income (loss) from operations, non-GAAP net income (loss), and non-GAAP diluted EPS useful metrics as they provide an alternative framework for assessing how our underlying business performed excluding non-cash long-lived asset impairment charges related to the impairment of our immersive healthcare asset group, the amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition, the excess tax benefits associated with share-based compensation arrangements, and expenses related to certain litigation matters that we have determined are not a normal or recurring part of our business, including settlement costs and legal fees. Further, we consider

------

adjusted EBITDA and adjusted EBITDA margin useful metrics as they provide an alternative framework for assessing how our underlying business performed excluding non-cash operating charges such as stock-based compensation, depreciation and amortization, and impairment charges, non-operating items such as interest income, interest expense, and provision for (benefit from) income taxes and non-recurring litigation related expenses.

The non-GAAP financial measures included in this press release may be different from, and therefore may not be comparable to, similarly titled measures used by other companies. These non-GAAP measures should not be considered in isolation or as alternatives to GAAP measures. We urge investors to review the reconciliation of these non-GAAP financial measures to the comparable GAAP financial measures included in this press release, and not to rely on any single financial measure to evaluate our business.

**Forward-Looking Statements**

Except for historical information, certain statements in this press release are forward-looking in nature and are subject to risks, uncertainties and assumptions about us. Our business and operations are subject to a variety of risks and uncertainties and, consequently, actual results may differ materially from those projected by any forward-looking statements. Factors that could cause actual results to differ from those projected include, but are not limited to: failure to sustain or grow profitability or generate positive cash flows; failure to effectively introduce and market new products; delays in product introductions; significant competition; inability to further penetrate our current customer base, expand our user base and increase the frequency of use of our products by our customers; inability to achieve or maintain satisfactory pricing and margins; manufacturing difficulties; permanent write-downs or write-offs of our inventory or other assets; product defects or failures; unfavorable outcomes in clinical trials; inability to maintain our culture as we grow; fluctuations in foreign currency exchange rates; potential adverse regulatory actions; and the potential impact of any acquisitions, mergers, dispositions, joint ventures or investments we may make. These risks and uncertainties, as well as others, are discussed in greater detail in our filings with the Securities and Exchange Commission ("SEC"), including our Annual Report on Form 10-K for the year ended December 31, 2024 filed with the SEC on February 18, 2025. There may be additional risks of which we are not presently aware or that we currently believe are immaterial which could have an adverse impact on our business. Any forward-looking statements are based on our current expectations, estimates and assumptions regarding future events and are applicable only as of the dates of such statements. We make no commitment to revise or update any forward-looking statements in order to reflect events or circumstances that may change.

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**Penumbra, Inc.**

**Condensed Consolidated Balance Sheets**

**(unaudited)**

**(in thousands)**

---

| | | |
|:---|:---|:---|
| | **June 30, 2025** | **December 31, 2024** |
| **Assets** | | |
| Current assets: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp; Cash and cash equivalents | $421768 | $324404 |
| &nbsp;&nbsp;&nbsp;&nbsp; Marketable investments | 2795 | 15727 |
| &nbsp;&nbsp;&nbsp;&nbsp; Accounts receivable, net | 175536 | 167668 |
| &nbsp;&nbsp;&nbsp;&nbsp; Inventories | 427628 | 406737 |
| &nbsp;&nbsp;&nbsp;&nbsp; Prepaid expenses and other current assets | 37757 | 36589 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total current assets | 1065484 | 951125 |
| Property and equipment, net | 84825 | 62641 |
| Operating lease right-of-use assets | 174059 | 177787 |
| Finance lease right-of-use assets | 27606 | 28018 |
| Intangible assets, net | 6552 | 6513 |
| Goodwill | 166752 | 165826 |
| Deferred taxes | 109141 | 100332 |
| Other non-current assets | 40390 | 40939 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total assets | $1674809 | $1533181 |
| **Liabilities and Stockholders' Equity** |  |  |
| Current liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp; Accounts payable | $28121 | $31326 |
| &nbsp;&nbsp;&nbsp;&nbsp; Accrued liabilities | 114389 | 112429 |
| &nbsp;&nbsp; Current operating lease liabilities | 12855 | 12221 |
| &nbsp;&nbsp; Current finance lease liabilities | 2396 | 2369 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total current liabilities | 157761 | 158345 |
| Non-current operating lease liabilities | 183493 | 187068 |
| Non-current finance lease liabilities | 21785 | 21731 |
| Other non-current liabilities | 17819 | 15106 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total liabilities | 380858 | 382250 |
| Stockholders' equity: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Common stock | 39 | 38 |
| &nbsp;&nbsp;&nbsp;&nbsp;Additional paid-in capital | 1146260 | 1096732 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accumulated other comprehensive income (loss) | 3155 | (5843) |
| &nbsp;&nbsp;&nbsp;&nbsp;Retained earnings | 144497 | 60004 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total stockholders' equity | 1293951 | 1150931 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total liabilities and stockholders' equity | $1674809 | $1533181 |

---

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**Penumbra, Inc.**

**Condensed Consolidated Statements of Operations**

**(unaudited)**

**(in thousands, except share and per share amounts)**

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended June 30,** | **Three Months Ended June 30,** | **Six Months Ended June 30,** | **Six Months Ended June 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| Revenue | $339455 | $299403 | $663595 | $578058 |
| Cost of revenue | 115445 | 136574 | 223702 | 234090 |
| &nbsp;&nbsp;&nbsp;&nbsp;Gross profit | 224010 | 162829 | 439893 | 343968 |
| Operating expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development | 23218 | 24942 | 45295 | 49568 |
| &nbsp;&nbsp;&nbsp;&nbsp;Sales, general and administrative | 159964 | 141903 | 313420 | 286315 |
| &nbsp;&nbsp;&nbsp;&nbsp;Impairment charge |  | 76945 |  | 76945 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | 183182 | 243790 | 358715 | 412828 |
| Income (loss) from operations | 40828 | (80961) | 81178 | (68860) |
| Interest and other income, net | 4482 | 3087 | 7990 | 5612 |
| Income (loss) before income taxes | 45310 | (77874) | 89168 | (63248) |
| Provision for (benefit from) income taxes | 40 | (17674) | 4675 | (14050) |
| Net income (loss) | $45270 | $(60200) | $84493 | $(49198) |
| Net income (loss) per share: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $1.17 | $(1.55) | $2.18 | $(1.27) |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $1.15 | $(1.55) | $2.15 | $(1.27) |
| Weighted average shares outstanding: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | 38834917 | 38793341 | 38699307 | 38755337 |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | 39245953 | 38793341 | 39214027 | 38755337 |

---

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**Penumbra, Inc.**

**Reconciliation of GAAP Operating Expenses and GAAP Income (Loss) from Operations to Non-GAAP Operating Expenses and Non-GAAP Income (Loss) from Operations**<sup>1</sup>

**(unaudited)**

**(in thousands)**

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended June 30,** | **Three Months Ended June 30,** | **Six Months Ended June 30,** | **Six Months Ended June 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| GAAP operating expenses | $183182 | $243790 | $358715 | $412828 |
| &nbsp;&nbsp;GAAP operating expenses includes the effect of the following items: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Impairment charge<sup>2</sup> |  | 76945 |  | 76945 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Non-recurring litigation related expenses |  |  |  | 4823 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Amortization of finite lived intangible assets acquired |  | 2380 |  | 4759 |
| Non-GAAP operating expenses | $183182 | $164465 | $358715 | $326301 |
| GAAP income (loss) from operations | $40828 | $(80961) | $81178 | $(68860) |
| &nbsp;&nbsp;GAAP income (loss) from operations includes the effect of the following items: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Impairment charge<sup>2</sup> |  | 76945 |  | 76945 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Non-recurring litigation related expenses |  |  |  | 4823 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Amortization of finite lived intangible assets acquired |  | 2380 |  | 4759 |
| Non-GAAP income (loss) from operations | $40828 | $(1636) | $81178 | $17667 |

---

<sup>1</sup>See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

<sup>2</sup>Represents charges associated with the impairment of the immersive healthcare asset group during the three months ended June 30, 2024.

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**Penumbra, Inc.**

**Reconciliation of GAAP Net Income (Loss) and GAAP Diluted EPS to Non-GAAP Net Income (Loss) and Non-GAAP Diluted EPS**<sup>1</sup>

**(unaudited)**

**(in thousands, except share and per share amounts)**

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Three Months Ended<br>June 30, 2025** | **Three Months Ended<br>June 30, 2025** | **Three Months Ended<br>June 30, 2024** | **Three Months Ended<br>June 30, 2024** | **Six Months Ended June 30, 2025** | **Six Months Ended June 30, 2025** | **Six Months Ended June 30, 2024** | **Six Months Ended June 30, 2024** |
| | **Net income** | **Diluted EPS** | **Net loss** | **Diluted EPS** | **Net income** | **Diluted EPS** | **Net (loss) income** | **Diluted EPS** |
| GAAP net income (loss) | $45270 | $1.15 | $(60200) | $(1.55) | $84493 | $2.15 | $(49198) | $(1.27) |
| &nbsp;&nbsp;&nbsp;GAAP net income (loss) includes the effect of the following items: |  |  |  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Impairment charge<sup>2</sup> |  |  | 76945 | 1.98 |  |  | 76945 | 1.97 |
| &nbsp;&nbsp;&nbsp;&nbsp;Non-recurring litigation related expenses |  |  |  |  |  |  | 4823 | 0.12 |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of finite lived intangible assets acquired |  |  | 2380 | 0.06 |  |  | 4759 | 0.12 |
| &nbsp;&nbsp;&nbsp;&nbsp;Tax effects on the non-GAAP adjustments above<sup>3</sup> |  |  | (19117) | (0.49) |  |  | (20853) | (0.52) |
| &nbsp;&nbsp;&nbsp;&nbsp;Excess tax benefits related to stock compensation awards | (11541) | (0.29) | (119) | 0.00 | (18134) | (0.46) | (406) | (0.01) |
| Non-GAAP net income (loss) | $33729 | $0.86 | $(111) | $— | $66359 | $1.69 | $16070 | $0.41 |
| GAAP diluted EPS |  | $1.15 |  | $(1.55) |  | $2.15 |  | $(1.27) |
| Non-GAAP diluted EPS |  | $0.86 |  | $0.00 |  | $1.69 |  | $0.41 |
| Weighted average shares outstanding used to compute: |  |  |  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;GAAP diluted EPS | 39245953 | 39245953 | 38793341 | 38793341 | 39214027 | 39214027 | 38755337 | 38755337 |
| &nbsp;&nbsp;Non-GAAP diluted EPS<sup>4</sup> | 39245953 | 39245953 | 38793341 | 38793341 | 39214027 | 39214027 | 39398553 | 39398553 |

---

<sup>1</sup>See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures. 

<sup>2</sup>Represents charges associated with the impairment of the immersive healthcare asset group during the three months ended June 30, 2024.

<sup>3</sup>For the three and six months ended June 30, 2024, management used a combined federal and state tax rate of 24.10% to compute the tax effect of non-GAAP adjustments.

<sup>4</sup>For the purposes of calculating non-GAAP diluted EPS for the six months ended June 30, 2024, non-GAAP diluted weighted average shares outstanding of 39,398,553 were used as the Company had non-GAAP net income in the period.

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**Penumbra, Inc.**

**Reconciliation of GAAP Net Income (Loss) and GAAP Net Income (Loss) Margin to Adjusted EBITDA and Adjusted EBITDA Margin**<sup>1</sup>

**(unaudited)**

**(in thousands, except for percentages)**

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended June 30,** | **Three Months Ended June 30,** | **Six Months Ended June 30,** | **Six Months Ended June 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| GAAP net income (loss) | $45270 | $(60200) | $84493 | $(49198) |
| Adjustments to GAAP net income (loss): |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Depreciation and amortization expense | 5507 | 7647 | 10522 | 15166 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Interest income, net | (3670) | (3313) | (6734) | (6204) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Provision for (benefit from) income taxes | 40 | (17674) | 4675 | (14050) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Stock-based compensation expense | 14234 | 9560 | 28019 | 23129 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Impairment charge<sup>2</sup> |  | 76945 |  | 76945 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Non-recurring litigation related expenses |  |  |  | 4823 |
| Adjusted EBITDA | $61381 | $12965 | $120975 | $50611 |
| Revenue | $339455 | $299403 | $663595 | $578058 |
| Adjusted EBITDA | $61381 | $12965 | $120975 | $50611 |
| GAAP net income (loss) margin | 13.3% | (20.1)% | 12.7% | (8.5)% |
| Adjusted EBITDA margin | 18.1% | 4.3% | 18.2% | 8.8% |

---

<sup>1</sup>See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures. 

<sup>2</sup>Represents charges associated with the impairment of the immersive healthcare asset group during the three months ended June 30, 2024.

------

**Penumbra, Inc.**

**Reconciliation of Revenue Growth by Geographic Regions to Constant Currency Revenue Growth**<sup>1</sup>

**(unaudited)**

**(in thousands, except for percentages)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **Three Months Ended June 30,** | **Three Months Ended June 30,** | **Reported Change** | **FX Impact** | **Constant Currency Change** |
| | **2025** | **2024** | $**%** | **$** | $**%** |
| United States | $260818 | $218180 | 19.5% | $— | 19.5% |
| International | 78637 | 81223 | (3.2)% | (2141) | (5.8)% |
| Total | $339455 | $299403 | 13.4% | $(2141) | 12.7% |

---

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **Six Months Ended June 30,** | **Six Months Ended June 30,** | **Reported Change** | **FX Impact** | **Constant Currency Change** |
| | **2025** | **2024** | $**%** | **$** | $**%** |
| United States | $517678 | $427824 | 21.0% | $— | 21.0% |
| International | 145917 | 150234 | (2.9)% | (483) | (3.2)% |
| Total | $663595 | $578058 | 14.8% | $(483) | 14.7% |

---

**Penumbra, Inc.**

**Reconciliation of Revenue Change by Product Categories to Constant Currency Revenue Growth**<sup>1</sup>

**(unaudited)**

**(in thousands, except for percentages)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **Three Months Ended June 30,** | **Three Months Ended June 30,** | **Reported Change** | **FX Impact** | **Constant Currency Change** |
| | **2025** | **2024** | $**%** | **$** | $**%** |
| Thrombectomy | $230256 | $203502 | 13.1% | $(1147) | 12.6% |
| Embolization and Access | 109199 | 95901 | 13.9% | (994) | 12.8% |
| Total | $339455 | $299403 | 13.4% | $(2141) | 12.7% |

---

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **Six Months Ended June 30,** | **Six Months Ended June 30,** | **Reported Change** | **FX Impact** | **Constant Currency Change** |
| | **2025** | **2024** | $**%** | **$** | $**%** |
| Thrombectomy | $456800 | $391205 | 16.8% | $(224) | 16.7% |
| Embolization and Access | 206795 | 186853 | 10.7% | (259) | 10.5% |
| Total | $663595 | $578058 | 14.8% | $(483) | 14.7% |

---

**Penumbra, Inc.**

**Reconciliation of Revenue Change by Product Categories and Geographic Regions to Constant Currency Revenue Growth**<sup>1</sup>

**(unaudited)**

**(in thousands, except for percentages)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **Three Months Ended June 30,** | **Three Months Ended June 30,** | **Reported Change** | **FX Impact** | **Constant Currency Change** |
| | **2025** | **2024** | $**%** | **$** | $**%** |
| **Thrombectomy** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;United States | $188533 | $153728 | 22.6% | $— | 22.6% |
| &nbsp;&nbsp;&nbsp;International | 41723 | 49774 | (16.2)% | (1147) | (18.5)% |
| &nbsp;&nbsp;&nbsp;&nbsp;Total Thrombectomy | 230256 | 203502 | 13.1% | (1147) | 12.6% |
| **Embolization and Access** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;United States | 72285 | 64452 | 12.2% |  | 12.2% |
| &nbsp;&nbsp;&nbsp;International | 36914 | 31449 | 17.4% | (994) | 14.2% |
| &nbsp;&nbsp;&nbsp;&nbsp;Total Embolization and Access | 109199 | 95901 | 13.9% | (994) | 12.8% |
| **Total** | $339455 | $299403 | 13.4% | $(2141) | 12.7% |

---

------

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **Six Months Ended June 30,** | **Six Months Ended June 30,** | **Reported Change** | **FX Impact** | **Constant Currency Change** |
| | **2025** | **2024** | $**%** | **$** | $**%** |
| **Thrombectomy** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;United States | $376425 | $304013 | 23.8% | $— | 23.8% |
| &nbsp;&nbsp;&nbsp;International | 80375 | 87192 | (7.8)% | (224) | (8.1)% |
| &nbsp;&nbsp;&nbsp;&nbsp;Total Thrombectomy | 456800 | 391205 | 16.8% | (224) | 16.7% |
| **Embolization and Access** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;United States | 141253 | 123811 | 14.1% |  | 14.1% |
| &nbsp;&nbsp;&nbsp;International | 65542 | 63042 | 4.0% | (259) | 3.6% |
| &nbsp;&nbsp;&nbsp;&nbsp;Total Embolization and Access | 206795 | 186853 | 10.7% | (259) | 10.5% |
| **Total** | $663595 | $578058 | 14.8% | $(483) | 14.7% |

---

<sup>1</sup>See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

**Investor Relations**

Penumbra, Inc.

<u>investors@penumbrainc.com</u>

Source: Penumbra, Inc.