# EDGAR Filing Document

**Accession Number:** 0001364608
**File Stem:** 0000940400-26-020540
**Filing Date:** 2026-5
**Character Count:** 17594
**Document Hash:** 854d696ddba8e5f3c883c14a90c437b2
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000940400-26-020540.hdr.sgml**: 20260521

**ACCESSION NUMBER**: 0000940400-26-020540

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260521

**DATE AS OF CHANGE**: 20260521

**PERIOD START**: 20260930

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIRST TRUST EXCHANGE-TRADED FUND II
- **CENTRAL INDEX KEY:** 0001364608

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MA

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-21944
- **FILM NUMBER:** 261007783

**BUSINESS ADDRESS:**
- **STREET 1:** 12O EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187
- **BUSINESS PHONE:** 630-765-8000

**MAIL ADDRESS:**
- **STREET 1:** 12O EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187

## Series and Classes Contracts Data

### First Trust Nasdaq Lux Digital Health Solutions ETF (Series ID: S000075528)

| Class ID   | Class Name                                          | Ticker Symbol   |
|:---|:---|:---|
| C000234707 | First Trust Nasdaq Lux Digital Health Solutions ETF | EKG             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** First Trust Exchange-Traded Fund II

- **b. Investment Company Act file number:** 811-21944

- **c. CIK number of Registrant:** 0001364608

- **d. LEI of Registrant:** 549300HY3NFBU00W8S30

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 120 East Liberty Drive

  - **City:** Wheaton

  - **State:** IL

  - **Foreign country:** US

  - **Zip / Postal Code:** 60187

  - **Telephone number:** 630-765-8000

**Item A.2. Information about the Series.**

- **a. Name of Series:** First Trust Nasdaq Lux Digital Health Solutions ETF

- **b. EDGAR series identifier (if any):** S000075528

- **c. LEI of Series:** 549300D67CSMMN7O4494

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-09-30

- **b. Date as of which information is reported:** 2026-03-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $2436884.17

**Total Liabilities:** $1403.95

**Net Assets:** $2435480.22

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000234707 | -0.05%               | -5.27%               | -9.73%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-903.96                 | $-4308.82                                  |
| Month 2  | $79085.28                | $-228322.29                                |
| Month 3  | $-50171.98               | $-210822.30                                |

### Schedule of Portfolio Investments

| Name                                         | Title                                                       | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Tempus AI Inc.                               | Tempus AI Inc. CL A                                         | CUSIP: 88023B103<br>LEI: 2549009LA0KWRAGQBX50 | Long             | EC               | CORP              | US        |      1799 | NS      | $81350.78     | 3.34%             |  |  |  | No            |                  1 | On Loan: No      |
| QIAGEN NV                                    | QIAGEN NV ORD SHARES                                        | CUSIP: 000000000<br>LEI: 54930036WK3GMCN17Z57 | Long             | EC               | CORP              | NL        |      2163 | NS      | $86606.52     | 3.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corporation                 | Twist Bioscience Corporation COM                            | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |       569 | NS      | $27038.88     | 1.11%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc.                                  | ResMed Inc. COM                                             | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |       841 | NS      | $188787.68    | 7.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Alphatec Holdings Inc.                       | Alphatec Holdings Inc. COM NEW                              | CUSIP: 02081G201<br>LEI: 549300EZE8CQ8K65FS24 | Long             | EC               | CORP              | US        |      2351 | NS      | $25578.88     | 1.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                                 | Doximity Inc CL A                                           | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1935 | NS      | $45085.50     | 1.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Morgan Stanley Institutional Liquidity Funds | Morgan Stanley Institutional Liquidity Funds TREAS PTF INST | CUSIP: 61747C582<br>LEI: 5493000A332Y142SOW84 | Long             | STIV             | RF                | US        |      4132 | NS      | $4131.94      | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| NATERA INC                                   | Natera Inc. COM                                             | CUSIP: 632307104<br>LEI: 529900CQ3OZ0A0VYVU59 | Long             | EC               | CORP              | US        |       518 | NS      | $103594.82    | 4.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health Inc                          | Guardant Health Inc COM                                     | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |      1147 | NS      | $105948.39    | 4.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                                 | Veracyte Inc COM                                            | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |       865 | NS      | $27861.65     | 1.14%             |  |  |  | No            |                  1 | On Loan: No      |
| QuidelOrtho Corp                             | QuidelOrtho Corp COM                                        | CUSIP: 219798105<br>LEI: 549300YU8CMO9HF53113 | Long             | EC               | CORP              | US        |       620 | NS      | $10186.60     | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp                | Adaptive Biotechnologies Corp COM                           | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |      2336 | NS      | $32423.68     | 1.33%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc                             | 10X Genomics Inc CL A COM                                   | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |      1323 | NS      | $28087.29     | 1.15%             |  |  |  | No            |                  1 | On Loan: No      |
| IRHYTHM HOLDINGS INC                         | iRhythm Holdings Inc. COM                                   | CUSIP: 450056106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       444 | NS      | $52400.88     | 2.15%             |  |  |  | No            |                  1 | On Loan: No      |
| HINGE HEALTH INC                             | Hinge Health, Inc. CL A                                     | CUSIP: 433313103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       498 | NS      | $19202.88     | 0.79%             |  |  |  | No            |                  1 | On Loan: No      |
| Caris Life Sciences Inc.                     | Caris Life Sciences Inc. COM                                | CUSIP: 142152107<br>LEI: 549300LX5LO78M5VPY43 | Long             | EC               | CORP              | US        |      1766 | NS      | $31576.08     | 1.30%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc.                          | IQVIA Holdings Inc. COM                                     | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |      1205 | NS      | $205500.70    | 8.44%             |  |  |  | No            |                  1 | On Loan: No      |
| HEARTFLOW INC                                | HeartFlow Inc. COM                                          | CUSIP: 42238D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1235 | NS      | $30047.55     | 1.23%             |  |  |  | No            |                  1 | On Loan: No      |
| PRIVIA HEALTH GROUP INC                      | Privia Health Group Inc. COM                                | CUSIP: 74276R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1501 | NS      | $30875.57     | 1.27%             |  |  |  | No            |                  1 | On Loan: No      |
| ESTABLISHMENT LABS HOLDINGS INC              | Establishment Labs Hldgs Inc COM                            | CUSIP: 000000000<br>LEI: 549300BCBQ714JNJ7V58 | Long             | EC               | CORP              | VG        |       473 | NS      | $26856.94     | 1.10%             |  |  |  | No            |                  1 | On Loan: No      |
| TransMedics Group Inc.                       | TransMedics Group Inc. COM                                  | CUSIP: 89377M109<br>LEI: 549300060GVOSMWARH50 | Long             | EC               | CORP              | US        |       380 | NS      | $37775.80     | 1.55%             |  |  |  | No            |                  1 | On Loan: No      |
| DexCom Inc                                   | DexCom Inc COM                                              | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |      2934 | NS      | $184255.20    | 7.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Med Inc                               | Globus Med Inc CL A                                         | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |      1128 | NS      | $97188.48     | 3.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Tandem Diabetes Care Inc                     | Tandem Diabetes Care Inc COM NEW                            | CUSIP: 875372203<br>LEI: 549300JEPFOD0K4D3I05 | Long             | EC               | CORP              | US        |       915 | NS      | $17540.55     | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                            | Veeva Systems Inc CL A COM                                  | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |      1183 | NS      | $207805.78    | 8.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc.                        | Align Technology Inc. COM                                   | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |       567 | NS      | $97200.81     | 3.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Neogenomics Inc                              | Neogenomics Inc COM NEW                                     | CUSIP: 64049M209<br>LEI: 549300KN62PPGHBVXB46 | Long             | EC               | CORP              | US        |      1761 | NS      | $13066.62     | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Hims & Hers Health Inc                       | Hims & Hers Health Inc COM CL A                             | CUSIP: 433000106<br>LEI: 254900V041EIVTSB6D58 | Long             | EC               | CORP              | US        |      2626 | NS      | $54515.76     | 2.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                                 | Illumina Inc COM                                            | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |       801 | NS      | $98731.26     | 4.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Schrodinger Inc.                             | Schrodinger Inc. COM                                        | CUSIP: 80810D103<br>LEI: 984500044BAE4791E559 | Long             | EC               | CORP              | US        |       773 | NS      | $8781.28      | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| LifeStance Health Group Inc                  | LifeStance Health Group Inc COM                             | CUSIP: 53228F101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2783 | NS      | $17727.71     | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Progyny Inc                                  | Progyny Inc COM                                             | CUSIP: 74340E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       863 | NS      | $14653.74     | 0.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corporation                          | Insulet Corporation COM                                     | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |       437 | NS      | $91700.08     | 3.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc                  | Inspire Medical Systems Inc COM                             | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |       403 | NS      | $20786.74     | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Teladoc Health Inc                           | Teladoc Health Inc COM                                      | CUSIP: 87918A105<br>LEI: 549300I2PVFBC9MFAC61 | Long             | EC               | CORP              | US        |      2580 | NS      | $14061.00     | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc.                      | Intuitive Surgical Inc. COM NEW                             | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |       428 | NS      | $197303.72    | 8.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Waystar Holding Corp                         | Waystar Holding Corp COM                                    | CUSIP: 946784105<br>LEI: 529900QJLKXDYU36MH89 | Long             | EC               | CORP              | US        |      1506 | NS      | $36309.66     | 1.49%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BIOROBOTICS CORP                     | Procept Biorobotics Corp. COM                               | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       705 | NS      | $17632.05     | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Oscar Health Inc                             | Oscar Health Inc CL A                                       | CUSIP: 687793109<br>LEI: 254900AE8KDLFDOPKZ19 | Long             | EC               | CORP              | US        |      4071 | NS      | $46694.37     | 1.92%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-05-21

**Name of Applicant:** First Trust Exchange-Traded Fund II

**Signature:** Derek Maltbie

**Name of Signer:** Derek Maltbie

**Title:** Treasurer, Chief Financial Officer and Chief Accounting Officer