# EDGAR Filing Document

**Accession Number:** 0001100663
**File Stem:** 0001004726-25-002051
**Filing Date:** 2025-11
**Character Count:** 20951
**Document Hash:** 685f2146f22979620fd57b9d9b3ebee0
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001004726-25-002051.hdr.sgml**: 20251125

**ACCESSION NUMBER**: 0001004726-25-002051

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250930

**FILED AS OF DATE**: 20251125

**DATE AS OF CHANGE**: 20251125

**PERIOD START**: 20260331

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** iSHARES TRUST
- **CENTRAL INDEX KEY:** 0001100663

**ORGANIZATION NAME:**
- **EIN:** 943351276
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-09729
- **FILM NUMBER:** 251519125

**BUSINESS ADDRESS:**
- **STREET 1:** 400 HOWARD STREET
- **CITY:** SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94105
- **BUSINESS PHONE:** (415) 670-2000

**MAIL ADDRESS:**
- **STREET 1:** 400 HOWARD STREET
- **CITY:** SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94105

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ISHARES TRUST
- **DATE OF NAME CHANGE:** 19991213

## Series and Classes Contracts Data

### iShares U.S. Pharmaceuticals ETF (Series ID: S000009417)

| Class ID   | Class Name                       | Ticker Symbol   |
|:---|:---|:---|
| C000025771 | iShares U.S. Pharmaceuticals ETF | IHE             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** iShares Trust

- **b. Investment Company Act file number:** 811-09729

- **c. CIK number of Registrant:** 0001100663

- **d. LEI of Registrant:** 5493000860OXIC4B5K91

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 400 Howard Street

  - **City:** San Francisco

  - **State:** CA

  - **Foreign country:** US

  - **Zip / Postal Code:** 94105

  - **Telephone number:** 800-474-2737

**Item A.2. Information about the Series.**

- **a. Name of Series:** iShares U.S. Pharmaceuticals ETF

- **b. EDGAR series identifier (if any):** S000009417

- **c. LEI of Series:** 549300K3OFF3L3ODU217

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-03-31

- **b. Date as of which information is reported:** 2025-09-30

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $619120122.94

**Total Liabilities:** $38361264.34

**Net Assets:** $580758858.60

**Cash Not Reported:** $788553.72

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000025771 | 0.28%                | 8.26%                | 2.49%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $2392660.62              | $-1242053.02                               |
| Month 2  | $939127.67               | $41786430.86                               |
| Month 3  | $-3780031.73             | $17633266.79                               |

### Schedule of Portfolio Investments

| Name                                                                       | Title                                             | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Collegium Pharmaceutical, Inc.                                             | COLLEGIUM PHARMACEUTICAL INC                      | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |     67135 | NS      | $2349053.65   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Mind Medicine (MindMed) Inc                                                | MIND MEDICINE MINDMED INC                         | CUSIP: 60255C885<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | CA        |    162160 | NS      | $1911866.40   | 0.33%             |  |  |  | No            |                  1 | On Loan: —       |
| BlackRock Funds III: BlackRock Cash Funds: Treasury; SL Agency Shares      | BLACKROCK CASH FUNDS TREASURY                     | CUSIP: 066922477<br>LEI: N/A                  | Long             | STIV             | RF                | US        |    251552 | NS      | $251552.17    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| AVADEL PHARMACEUTICALS PUBLIC LIMITED COMPANY                              | AVADEL PHARMACEUTICALS PLC                        | CUSIP: G29687103<br>LEI: 549300E27PTSG2RHC762 | Long             | EC               | CORP              | IE        |    207284 | NS      | $3165226.68   | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| LIGAND PHARMACEUTICALS INCORPORATED                                        | LIGAND PHARMACEUTICALS                            | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |     41780 | NS      | $7400909.20   | 1.27%             |  |  |  | No            |                  1 | On Loan: —       |
| ELANCO ANIMAL HEALTH INCORPORATED                                          | ELANCO ANIMAL HEALTH INC                          | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |   1059178 | NS      | $21331844.92  | 3.67%             |  |  |  | No            |                  1 | On Loan: —       |
| BlackRock Funds III: BlackRock Cash Funds: Institutional; SL Agency Shares | BLACKROCK CASH FUNDS INSTITUTIONAL FUND SL AGENCY | CUSIP: 066922519<br>LEI: N/A                  | Long             | STIV             | RF                | US        |  38118126 | NS      | $38137185.32  | 6.57%             |  |  |  | No            |                  1 | On Loan: No      |
| PHATHOM PHARMACEUTICALS, INC.                                              | PHATHOM PHARMACEUTICALS INC                       | CUSIP: 71722W107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     96765 | NS      | $1138924.05   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| WAVE Life Sciences Ltd                                                     | WAVE LIFE SCIENCES LTD                            | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | SG        |    261297 | NS      | $1912694.04   | 0.33%             |  |  |  | No            |                  1 | On Loan: —       |
| BRISTOL-MYERS SQUIBB COMPANY                                               | BRISTOL MYERS SQUIBB CO                           | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |    540131 | NS      | $24359908.10  | 4.19%             |  |  |  | No            |                  1 | On Loan: No      |
| PERRIGO COMPANY PUBLIC LIMITED COMPANY                                     | PERRIGO CO PLC                                    | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | IE        |    293319 | NS      | $6532214.13   | 1.12%             |  |  |  | No            |                  1 | On Loan: No      |
| ELI LILLY AND COMPANY                                                      | ELI LILLY CO                                      | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |    168742 | NS      | $128750146.00 | 22.17%            |  |  |  | No            |                  1 | On Loan: No      |
| XAV HEALTH CARE DEC25                                                      | XAV HEALTH CARE DEC25                             | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |         2 | NC      | $5446.93      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| JAZZ PHARMACEUTICALS PUBLIC LIMITED COMPANY                                | JAZZ PHARMACEUTICALS PLC                          | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | IE        |    129321 | NS      | $17044507.80  | 2.93%             |  |  |  | No            |                  1 | On Loan: No      |
| ZOETIS INC.                                                                | ZOETIS INC                                        | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |    170440 | NS      | $24938780.80  | 4.29%             |  |  |  | No            |                  1 | On Loan: No      |
| JOHNSON & JOHNSON                                                          | JOHNSON JOHNSON                                   | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |    724364 | NS      | $134311572.88 | 23.13%            |  |  |  | No            |                  1 | On Loan: No      |
| OCULAR THERAPEUTIX, INC.                                                   | OCULAR THERAPEUTIX INC                            | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |    281839 | NS      | $3294697.91   | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| INNOVIVA, INC.                                                             | INNOVIVA INC                                      | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |    127592 | NS      | $2328554.00   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc                                                  | EDGEWISE THERAPEUTICS INC                         | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    157183 | NS      | $2549508.26   | 0.44%             |  |  |  | No            |                  1 | On Loan: —       |
| Evolus Inc                                                                 | EVOLUS INC                                        | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |    137856 | NS      | $846435.84    | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| LENZ Therapeutics Inc                                                      | LENZ THERAPEUTICS INC                             | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     42550 | NS      | $1981979.00   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| AXSOME THERAPEUTICS, INC.                                                  | AXSOME THERAPEUTICS INC                           | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |     89364 | NS      | $10853257.80  | 1.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Tarsus Pharmaceuticals Inc                                                 | TARSUS PHARMACEUTICALS INC                        | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     82777 | NS      | $4919437.11   | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                                                                | ARVINAS INC                                       | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    156469 | NS      | $1333115.88   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| HARMONY BIOSCIENCES HOLDINGS, INC.                                         | HARMONY BIOSCIENCES HOLDINGS INC                  | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     84778 | NS      | $2336481.68   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvation Bio Inc                                                           | NUVATION BIO INC                                  | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    510619 | NS      | $1889290.30   | 0.33%             |  |  |  | No            |                  1 | On Loan: —       |
| ORGANON & CO.                                                              | ORGANON CO                                        | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |    554215 | NS      | $5919016.20   | 1.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Crinetics Pharmaceuticals Inc                                              | CRINETICS PHARMACEUTICALS INC                     | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |    200969 | NS      | $8370358.85   | 1.44%             |  |  |  | No            |                  1 | On Loan: —       |
| PFIZER INC.                                                                | PFIZER INC                                        | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |   1036516 | NS      | $26410427.68  | 4.55%             |  |  |  | No            |                  1 | On Loan: No      |
| HARROW, INC.                                                               | HARROW INC                                        | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     70193 | NS      | $3381898.74   | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| NEKTAR THERAPEUTICS                                                        | NEKTAR THERAPEUTICS                               | CUSIP: 640268306<br>LEI: 5299005I24806IOIYE03 | Long             | EC               | CORP              | US        |     40536 | NS      | $2306498.40   | 0.40%             |  |  |  | No            |                  1 | On Loan: —       |
| Amylyx Pharmaceuticals Inc                                                 | AMYLYX PHARMACEUTICALS INC                        | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    172830 | NS      | $2348759.70   | 0.40%             |  |  |  | No            |                  1 | On Loan: —       |
| CORCEPT THERAPEUTICS INCORPORATED                                          | CORCEPT THERAPEUTICS INC                          | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |    199936 | NS      | $16616680.96  | 2.86%             |  |  |  | No            |                  1 | On Loan: —       |
| AMPHASTAR PHARMACEUTICALS INC                                              | AMPHASTAR PHARMACEUTICALS INC                     | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |     76299 | NS      | $2033368.35   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| MERCK & CO., INC.                                                          | MERCK CO INC                                      | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |    303073 | NS      | $25436916.89  | 4.38%             |  |  |  | No            |                  1 | On Loan: No      |
| PHIBRO ANIMAL HEALTH CORPORATION                                           | PHIBRO ANIMAL HEALTH CORP                         | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |     43409 | NS      | $1756328.14   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| AMNEAL PHARMACEUTICALS, INC.                                               | AMNEAL PHARMACEUTICALS INC                        | CUSIP: 03168L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    361458 | NS      | $3618194.58   | 0.62%             |  |  |  | No            |                  1 | On Loan: —       |
| ANI PHARMACEUTICALS, INC.                                                  | ANI PHARMACEUTICALS INC                           | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |     36888 | NS      | $3378940.80   | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| SUPERNUS PHARMACEUTICALS, INC.                                             | SUPERNUS PHARMACEUTICALS INC                      | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |    119541 | NS      | $5712864.39   | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| PRESTIGE CONSUMER HEALTHCARE INC.                                          | PRESTIGE CONSUMER HEALTH                          | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    104921 | NS      | $6547070.40   | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc                                                   | ENLIVEN THERAPEUTICS INC                          | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     94683 | NS      | $1938161.01   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Liquidia Corp                                                              | LIQUIDIA CORP                                     | CUSIP: 53635D202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    145185 | NS      | $3301506.90   | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| THERAVANCE BIOPHARMA, INC.                                                 | THERAVANCE BIOPHARMA INC                          | CUSIP: G8807B106<br>LEI: 5493007VTSXP4Z6MIW52 | Long             | EC               | CORP              | KY        |     78350 | NS      | $1143910.00   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| PACIRA BIOSCIENCES, INC.                                                   | PACIRA BIOSCIENCES INC                            | CUSIP: 695127100<br>LEI: 549300P56LERYBDHCF69 | Long             | EC               | CORP              | US        |     95757 | NS      | $2467657.89   | 0.42%             |  |  |  | No            |                  1 | On Loan: —       |
| ROYALTY PHARMA PLC                                                         | ROYALTY PHARMA PLC                                | CUSIP: G7709Q104<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |    703903 | NS      | $24833697.84  | 4.28%             |  |  |  | No            |                  1 | On Loan: No      |
| VIATRIS INC.                                                               | VIATRIS INC                                       | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |   2485570 | NS      | $24607143.00  | 4.24%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-10-30

**Name of Applicant:** iShares Trust

**Signature:** Chuck Pulsfort

**Name of Signer:** Chuck Pulsfort

**Title:** Assistant Treasurer