# EDGAR Filing Document

**Accession Number:** 0000097745
**File Stem:** 0000097745-23-000003
**Filing Date:** 2023-2
**Character Count:** 64101
**Document Hash:** 9e75e3b323c94353822a1b8bbdd07a04
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000097745-23-000003.hdr.sgml**: 20230201

**ACCESSION NUMBER**: 0000097745-23-000003

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 15

**CONFORMED PERIOD OF REPORT**: 20230201

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20230201

**DATE AS OF CHANGE**: 20230201

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** THERMO FISHER SCIENTIFIC INC.
- **CENTRAL INDEX KEY:** 0000097745
- **STANDARD INDUSTRIAL CLASSIFICATION:** MEASURING & CONTROLLING DEVICES, NEC [3829]
- **IRS NUMBER:** 042209186
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-08002
- **FILM NUMBER:** 23574638

**BUSINESS ADDRESS:**
- **STREET 1:** 168 THIRD AVENUE
- **CITY:** WALTHAM
- **STATE:** MA
- **ZIP:** 02451
- **BUSINESS PHONE:** 7816221000

**MAIL ADDRESS:**
- **STREET 1:** 168 THIRD AVENUE
- **CITY:** WALTHAM
- **STATE:** MA
- **ZIP:** 02451

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** THERMO ELECTRON CORP
- **DATE OF NAME CHANGE:** 19920703

?xml version="1.0" ? tmo-20230201

**UNITED STATES SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 8-K** 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): February 1, 2023

**THERMO FISHER SCIENTIFIC INC.** 

*(Exact name of Registrant as specified in its Charter)*

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| | | |
|:---|:---|:---|
| Delaware | 1-8002 | 04-2209186 |
| *(State of incorporation)* | *(Commission File Number)* | *(I.R.S. Employer Identification Number)* |

---

168 Third Avenue

Waltham, Massachusetts 02451

*(Address of principal executive offices) (Zip Code)*

Registrant's telephone number, including area code: (781) 622-1000

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (*see* General Instruction A.2. below):

☐&nbsp;&nbsp;&nbsp;&nbsp; Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ &nbsp;&nbsp;&nbsp;&nbsp; Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐&nbsp;&nbsp;&nbsp;&nbsp; Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐&nbsp;&nbsp;&nbsp;&nbsp; Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| Title of each class | Trading Symbol(s) | Name of each exchange on which registered |
| Common Stock, $1.00 par value | TMO | New York Stock Exchange |
| 0.750% Notes due 2024 | TMO 24A | New York Stock Exchange |
| 0.125% Notes due 2025 | TMO 25B | New York Stock Exchange |
| 2.000% Notes due 2025 | TMO 25 | New York Stock Exchange |
| 3.200% Notes due 2026 | TMO 26B | New York Stock Exchange |
| 1.400% Notes due 2026 | TMO 26A | New York Stock Exchange |
| 1.450% Notes due 2027 | TMO 27 | New York Stock Exchange |
| 1.750% Notes due 2027 | TMO 27B | New York Stock Exchange |
| 0.500% Notes due 2028 | TMO 28A | New York Stock Exchange |
| 1.375% Notes due 2028 | TMO 28 | New York Stock Exchange |
| 1.950% Notes due 2029 | TMO 29 | New York Stock Exchange |
| 0.875% Notes due 2031 | TMO 31 | New York Stock Exchange |
| 2.375% Notes due 2032 | TMO 32 | New York Stock Exchange |
| 3.650% Notes due 2034 | TMO 34 | New York Stock Exchange |
| 2.875% Notes due 2037 | TMO 37 | New York Stock Exchange |
| 1.500% Notes due 2039 | TMO 39 | New York Stock Exchange |
| 1.875% Notes due 2049 | TMO 49 | New York Stock Exchange |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).&nbsp;&nbsp;&nbsp;&nbsp;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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**THERMO FISHER SCIENTIFIC INC.**

**Item 2.02&nbsp;&nbsp;&nbsp;&nbsp;Results of Operations and Financial Condition**

On February 1, 2023, the Registrant announced its financial results for the fiscal quarter and year ended December 31, 2022. The full text of the press release issued in connection with the announcement is furnished as Exhibit 99.1 to this Form 8-K and incorporated herein by reference.

The information contained in this report and exhibits hereto shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such filing.

**Item 9.01&nbsp;&nbsp;&nbsp;&nbsp;Financial Statements and Exhibits**

(d)&nbsp;&nbsp;&nbsp;&nbsp;Exhibits

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<u>[99.1](q42022earnings8kex99_1.htm)</u> Press Release dated February 1, 2023

104 Cover Page Interactive Data File (embedded within the Inline XBRL document).

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**THERMO FISHER SCIENTIFIC INC.**

**SIGNATURE**

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | | |
|:---|:---|:---|:---|
| | | THERMO FISHER SCIENTIFIC INC. | THERMO FISHER SCIENTIFIC INC. |
| Date: | February 1, 2023 | By: | /s/ Joseph R. Holmes |
|  |  |  | Joseph R. Holmes |
|  |  |  | Vice President and Chief Accounting Officer |

---

## Exhibit 99.1

**Exhibit 99.1**

![logo.jpg](logo.jpg)

News

---

| | |
|:---|:---|
| **FOR IMMEDIATE RELEASE** | |
| Media Contact Information:<br>Sandy Pound | Investor Contact Information:<br>Rafael Tejada |
| Thermo Fisher Scientific | Thermo Fisher Scientific |
| Phone: 781-622-1223 | Phone: 781-622-1356 |
| E-mail: sandy.pound@thermofisher.com | E-mail: rafael.tejada@thermofisher.com |

---

**Thermo Fisher Scientific Reports Fourth Quarter and Full Year 2022 Results**

**WALTHAM, Mass**. (February 1, 2023) – Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science, today reported its financial results for the fourth quarter and full year ended December 31, 2022.

**Fourth Quarter and Full Year 2022 Highlights**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Fourth quarter revenue grew 7% to $11.45 billion.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Fourth quarter GAAP diluted earnings per share (EPS) was $4.01.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Fourth quarter adjusted EPS was $5.40.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full year revenue grew 15% to $44.92 billion.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full year GAAP diluted EPS was $17.63.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full year adjusted EPS was $23.24.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• During the year, we strengthened our industry leadership, advanced our trusted partner status with our customers, delivered excellent financial performance for our shareholders, and invested in our world class team.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Achieved outstanding and differentiated Core organic revenue growth, growing 14% in both the fourth quarter and for the full year.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Delivered another outstanding year of high-impact innovation, highlighted by the Applied Biosystems SeqStudio Flex Series genetic analyzer, the Thermo Scientific TRACE 1600 Series Gas Chromatograph**,** the Phadia 2500+ series of instruments, as well as the Orbitrap Ascend Tribrid mass spectrometer. During the quarter, we launched the Thermo Scientific Glacios 2 Cryo-TEM (transmission electron microscope) to accelerate structure-based drug discovery, the Gibco CTS DynaCellect Magnetic Separation System to advance the manufacturing of cell therapies, and the SeCore CDx HLA Sequencing System, which received marketing authorization by the FDA for use as a companion diagnostic with an immunotherapy to treat patients with a rare eye cancer.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Continued to strengthen our unique customer value proposition by adding capacity and capabilities globally for pharma services, bioproduction, and clinical research services. During the fourth quarter, this included the opening of a new state-of-the-art bioanalytical lab in Richmond, Virginia, to support our clinical research business and the increasing demand for analytical services to accelerate drug development.

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![logo.jpg](logo.jpg)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Advanced our industry-leading scale and depth of capabilities in high-growth and emerging markets. During the fourth quarter, this included opening a new biologics manufacturing facility in Hangzhou, China, to offer integrated clinical and commercial drug substance and drug product capabilities for customers.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Very active year advancing our environmental, social and governance (ESG) priorities. We made strong progress on our Scope 1 and Scope 2 emissions initiatives, enabling us to increase our 2030 greenhouse gas emissions reduction target and accelerate our transition to 100% renewable energy. Among the highlights from our Foundation for Science, we supported students across the globe through our STEM education programs and colleague-led Community Action Councils. Throughout the year, the company also received a variety of awards and recognition for its industry leadership and inclusive culture including being recognized by *Forbes* magazine during the quarter as one of the World's Top Female-Friendly Companies and one of America's Best Employers for veterans.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Continued to successfully execute our capital deployment strategy in 2022. The integration of PPD is largely complete and drove strong returns for our shareholders with outstanding execution and business performance throughout the year. For the full year, PPD delivered outstanding Core organic revenue growth and is on track to deliver total synergies of $175 million by year 3. Additionally, we returned $3.5 billion of capital to shareholders through stock buybacks and dividends. Shortly after year end, we completed the acquisition of The Binding Site for $2.7 billion.

"We had another exceptional year, exceeding our goals and delivering for all of our stakeholders in 2022," said Marc N. Casper, chairman, president and chief executive officer of Thermo Fisher Scientific. "Thanks to our incredible global team, we successfully executed our proven growth strategy, effectively navigated the macro-environment, and delivered impressive financial results, as we continued to enable our customers to make the world healthier, cleaner and safer."

Casper added, "We are incredibly well positioned as we enter 2023. Our high-impact innovation and unique customer value proposition continue to drive significant share gain. Our experienced management team, PPI Business System and the benefits of scale, position our company to deliver another outstanding year of value creation for all of our stakeholders and ensure we create an even brighter future."

**Fourth Quarter 2022**

Revenue for the quarter grew 7% to $11.45 billion in 2022, versus $10.70 billion in 2021. Organic revenue was 3% lower, Core organic revenue growth was 14%, and COVID-19 testing revenue was $0.37 billion.

*GAAP Earnings Results*

GAAP diluted EPS in the fourth quarter of 2022 was $4.01, versus $4.17 in the same quarter last year. GAAP operating income for the fourth quarter of 2022 was $1.86 billion, compared with $2.54 billion in the year-ago quarter. GAAP operating margin was 16.3%, compared with 23.7% in the fourth quarter of 2021.

*Non-GAAP Earnings Results*

Adjusted EPS in the fourth quarter of 2022 was $5.40, versus $6.54 in the fourth quarter of 2021. Adjusted operating income for the fourth quarter of 2022 was $2.56 billion, compared with $3.16 billion in the year-ago quarter. Adjusted operating margin was 22.4%, compared with 29.5% in the fourth quarter of 2021.<br>

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![logo.jpg](logo.jpg)

**Full Year 2022**

Revenue for the full year grew 15% to $44.92 billion in 2022, versus $39.21 billion in 2021. Organic revenue grew slightly, Core organic revenue growth was 14%, and COVID-19 testing revenue was $3.11 billion.

*GAAP Earnings Results*

GAAP diluted EPS for the full year was $17.63, versus $19.46 in 2021. GAAP operating income for 2022 was $8.39 billion, compared with $10.03 billion a year-ago. GAAP operating margin was 18.7%, compared with 25.6% in 2021.

*Non-GAAP Earnings Results*

Adjusted EPS for the full year was $23.24, versus $25.13 in 2021. Adjusted operating income for the full year was $10.99 billion, compared with $12.14 billion a year-ago. Adjusted operating margin was 24.5%, compared with 31.0% in 2021.

**Annual Guidance for 2023**

Thermo Fisher is initiating revenue and adjusted EPS guidance for the full year 2023. The company expects to achieve 2023 revenue of $45.3 billion and full year Core organic revenue growth of 7%. The company expects to achieve adjusted EPS of $23.70.

**Use of Non-GAAP Financial Measures**

Adjusted EPS, adjusted net income, adjusted operating income, adjusted operating margin, free cash flow, organic revenue growth and Core organic revenue growth are non-GAAP measures that exclude certain items detailed after the tables that accompany this press release, under the heading "Supplemental Information Regarding Non-GAAP Financial Measures." The reconciliations of GAAP to non-GAAP financial measures are provided in the tables that accompany this press release.

**Conference Call**

Thermo Fisher Scientific will hold its earnings conference call today, February 1, 2023, at 8:30 a.m. Eastern Time. To listen, dial (844) 200-6205 within the U.S. or (929) 526-1599 outside the U.S. The conference ID is 982319. You may also listen to the call live on our website, www.thermofisher.com, by clicking on "Investors." You will find this press release, including the accompanying reconciliation of non-GAAP financial measures and related information, in that section of our website under "Financials." An audio archive of the call will be available under "News & Events" through Friday, February 17, 2023.

**About Thermo Fisher Scientific**

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue over $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our global team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit www.thermofisher.com.

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![logo.jpg](logo.jpg)

**Safe Harbor Statement**

The following constitutes a "Safe Harbor" statement under the Private Securities Litigation Reform Act of 1995: This press release contains forward-looking statements that involve a number of risks and uncertainties. Important factors that could cause actual results to differ materially from those indicated by forward-looking statements include risks and uncertainties relating to: the duration and severity of the COVID-19 pandemic; the need to develop new products and adapt to significant technological change; implementation of strategies for improving growth; general economic conditions and related uncertainties; dependence on customers' capital spending policies and government funding policies; the effect of economic and political conditions and exchange rate fluctuations on international operations; use and protection of intellectual property; the effect of changes in governmental regulations; any natural disaster, public health crisis or other catastrophic event; and the effect of laws and regulations governing government contracts, as well as the possibility that expected benefits related to recent or pending acquisitions may not materialize as expected. Additional important factors that could cause actual results to differ materially from those indicated by such forward-looking statements are set forth in our most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q, which are on file with the SEC and available in the "Investors" section of our website under the heading "SEC Filings." While we may elect to update forward-looking statements at some point in the future, we specifically disclaim any obligation to do so, even if estimates change and, therefore, you should not rely on these forward-looking statements as representing our views as of any date subsequent to today.

###

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| | | | | |
|:---|:---|:---|:---|:---|
| **Condensed Consolidated Statement of Income (unaudited)** | | | | |
|  | Three Months Ended | Three Months Ended | Three Months Ended | Three Months Ended |
|  | December 31, | % of | December 31, | % of |
| (In millions except per share amounts) | 2022 | Revenues | 2021 | Revenues |
| Revenues | $11450 |  | $10702 |  |
| Costs and operating expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues (a) | 6715 | 58.6% | 5302 | 49.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses (b) | 1836 | 16.0% | 1958 | 18.3% |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 592 | 5.2% | 466 | 4.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development expenses | 391 | 3.4% | 392 | 3.7% |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 55 | 0.5% | 46 | 0.4% |
|  | 9589 | 83.7% | 8164 | 76.3% |
| Operating income | 1861 | 16.3% | 2538 | 23.7% |
| Interest income | 150 |  | 11 |  |
| Interest expense | (269) |  | (161) |  |
| Other income/(expense) (d) | 35 |  | (526) |  |
| Income before income taxes | 1777 |  | 1862 |  |
| Provision for income taxes (e) | (173) |  | (202) |  |
| Equity in earnings/(losses) of unconsolidated entities | (30) |  | (1) |  |
| Net income | 1574 |  | 1659 |  |
| Less: net income/(losses) attributable to noncontrolling interests and redeemable noncontrolling interest | (2) |  | 1 |  |
| Net income attributable to Thermo Fisher Scientific Inc. | $1576 | 13.8% | $1658 | 15.5% |
| Earnings per share attributable to Thermo Fisher Scientific Inc.: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $4.03 |  | $4.20 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $4.01 |  | $4.17 |  |
| Weighted average shares: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | 391 |  | 394 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | 393 |  | 398 |  |
| **Reconciliation of adjusted operating income and adjusted operating margin** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP operating income | $1861 | 16.3% | $2538 | 23.7% |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | 5 | 0.0% |  | 0.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | 47 | 0.4% | 111 | 1.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 55 | 0.5% | 46 | 0.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 592 | 5.2% | 466 | 4.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjusted operating income (non-GAAP measure) | $2560 | 22.4% | $3161 | 29.5% |
| **Reconciliation of adjusted net income** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP net income attributable to Thermo Fisher Scientific Inc. | $1576 |  | $1658 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | 5 |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | 47 |  | 111 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 55 |  | 46 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 592 |  | 466 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income/expense adjustments (d) | (46) |  | 532 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Provision for income taxes adjustments (e) | (138) |  | (213) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Equity in earnings/losses of unconsolidated entities | 30 |  | 1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjusted net income (non-GAAP measure) | $2121 |  | $2601 |  |
| **Reconciliation of adjusted earnings per share** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP diluted EPS attributable to Thermo Fisher Scientific Inc. | $4.01 |  | $4.17 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | 0.01 |  | 0.00 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | 0.12 |  | 0.28 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 0.14 |  | 0.11 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 1.50 |  | 1.17 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income/expense adjustments (d) | (0.11) |  | 1.34 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Provision for income taxes adjustments (e) | (0.35) |  | (0.53) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Equity in earnings/losses of unconsolidated entities | 0.08 |  | 0.00 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjusted EPS (non-GAAP measure) | $5.40 |  | $6.54 |  |
| **Reconciliation of free cash flow** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP net cash provided by operating activities | $3487 |  | $2457 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Purchases of property, plant and equipment | (550) |  | (831) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Proceeds from sale of property, plant and equipment | 6 |  | 11 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Free cash flow (non-GAAP measure) | $2943 |  | $1637 |  |

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| | | | | |
|:---|:---|:---|:---|:---|
| **Segment data** | Three Months Ended | Three Months Ended | Three Months Ended | Three Months Ended |
|  | December 31, | % of | December 31, | % of |
| (In millions) | 2022 | Revenues | 2021 | Revenues |
| **Revenues** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Life Sciences Solutions | $3046 | 26.6% | $4150 | 38.8% |
| &nbsp;&nbsp;&nbsp;&nbsp;Analytical Instruments | 1878 | 16.4% | 1725 | 16.1% |
| &nbsp;&nbsp;&nbsp;&nbsp;Specialty Diagnostics | 1115 | 9.7% | 1447 | 13.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Laboratory Products and Biopharma Services | 5947 | 51.9% | 4195 | 39.2% |
| &nbsp;&nbsp;&nbsp;&nbsp;Eliminations | (536) | -4.6% | (815) | -7.6% |
| &nbsp;&nbsp;&nbsp;&nbsp;Consolidated revenues | $11450 | 100.0% | $10702 | 100.0% |
| **Operating income and operating margin** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Life Sciences Solutions | $1040 | 34.1% | $1999 | 48.2% |
| &nbsp;&nbsp;&nbsp;&nbsp;Analytical Instruments | 476 | 25.4% | 381 | 22.1% |
| &nbsp;&nbsp;&nbsp;&nbsp;Specialty Diagnostics | 208 | 18.6% | 297 | 20.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Laboratory Products and Biopharma Services | 836 | 14.1% | 484 | 11.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Subtotal reportable segments | 2560 | 22.4% | 3161 | 29.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | (5) | 0.0% |  | 0.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | (47) | -0.4% | (111) | -1.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | (55) | -0.5% | (46) | -0.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | (592) | -5.2% | (466) | -4.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP operating income | $1861 | 16.3% | $2538 | 23.7% |
| &nbsp;&nbsp;(a) Adjusted results in 2022 exclude charges for inventory write-downs associated with large-scale abandonment of product lines. | &nbsp;&nbsp;(a) Adjusted results in 2022 exclude charges for inventory write-downs associated with large-scale abandonment of product lines. | &nbsp;&nbsp;(a) Adjusted results in 2022 exclude charges for inventory write-downs associated with large-scale abandonment of product lines. | &nbsp;&nbsp;(a) Adjusted results in 2022 exclude charges for inventory write-downs associated with large-scale abandonment of product lines. | &nbsp;&nbsp;(a) Adjusted results in 2022 exclude charges for inventory write-downs associated with large-scale abandonment of product lines. |
| &nbsp;&nbsp;(b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | &nbsp;&nbsp;(b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | &nbsp;&nbsp;(b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | &nbsp;&nbsp;(b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | &nbsp;&nbsp;(b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. |
| &nbsp;&nbsp;(c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility, and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $22 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | &nbsp;&nbsp;(c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility, and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $22 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | &nbsp;&nbsp;(c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility, and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $22 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | &nbsp;&nbsp;(c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility, and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $22 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | &nbsp;&nbsp;(c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility, and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $22 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. |
| &nbsp;&nbsp;(d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $4 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $570 of losses on the early extinguishment of debt and $10 of charges for the amortization of bridge loan commitment fees related to recent acquisitions. | &nbsp;&nbsp;(d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $4 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $570 of losses on the early extinguishment of debt and $10 of charges for the amortization of bridge loan commitment fees related to recent acquisitions. | &nbsp;&nbsp;(d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $4 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $570 of losses on the early extinguishment of debt and $10 of charges for the amortization of bridge loan commitment fees related to recent acquisitions. | &nbsp;&nbsp;(d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $4 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $570 of losses on the early extinguishment of debt and $10 of charges for the amortization of bridge loan commitment fees related to recent acquisitions. | &nbsp;&nbsp;(d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $4 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $570 of losses on the early extinguishment of debt and $10 of charges for the amortization of bridge loan commitment fees related to recent acquisitions. |
| &nbsp;&nbsp;(e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements. | &nbsp;&nbsp;(e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements. | &nbsp;&nbsp;(e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements. | &nbsp;&nbsp;(e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements. | &nbsp;&nbsp;(e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements. |
| &nbsp;&nbsp;Note: | &nbsp;&nbsp;Note: | &nbsp;&nbsp;Note: | &nbsp;&nbsp;Note: | &nbsp;&nbsp;Note: |
| &nbsp;&nbsp;Consolidated depreciation expense is $256 and $217 in 2022 and 2021, respectively. | &nbsp;&nbsp;Consolidated depreciation expense is $256 and $217 in 2022 and 2021, respectively. | &nbsp;&nbsp;Consolidated depreciation expense is $256 and $217 in 2022 and 2021, respectively. | &nbsp;&nbsp;Consolidated depreciation expense is $256 and $217 in 2022 and 2021, respectively. | &nbsp;&nbsp;Consolidated depreciation expense is $256 and $217 in 2022 and 2021, respectively. |

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| | |
|:---|:---|
| **Organic and Core organic revenue growth** | Three months ended |
|  | December 31, 2022 |
| **Revenue growth** | 7% |
| Acquisitions | 14% |
| Currency translation | -4% |
| **Organic revenue growth** | -3% |
| COVID-19 testing revenue | -16% |
| Contribution of PPD to Core organic revenue growth (a) | 1% |
| **Core organic revenue growth** | 14% |
| (a) Adjustment to include the contribution of PPD to Core organic revenue growth as though the acquisition had occurred on January 1, 2021. | (a) Adjustment to include the contribution of PPD to Core organic revenue growth as though the acquisition had occurred on January 1, 2021. |
| Note: | Note: |
| For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. | For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. |

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------

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| | | | | |
|:---|:---|:---|:---|:---|
| **Condensed Consolidated Statement of Income (unaudited)** | | | | |
|  | Year ended | Year ended | Year ended | Year ended |
|  | December 31, | % of | December 31, | % of |
| (In millions except per share amounts) | 2022 | Revenues | 2021 | Revenues |
| Revenues | $44915 |  | $39211 |  |
| Costs and operating expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues (a) | 25415 | 56.6% | 18977 | 48.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses (b) | 7127 | 15.9% | 6842 | 17.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 2395 | 5.3% | 1761 | 4.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development expenses | 1471 | 3.3% | 1406 | 3.6% |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 114 | 0.3% | 197 | 0.5% |
|  | 36522 | 81.3% | 29183 | 74.4% |
| Operating income | 8393 | 18.7% | 10028 | 25.6% |
| Interest income | 272 |  | 43 |  |
| Interest expense | (726) |  | (536) |  |
| Other income/(expense) (d) | (104) |  | (694) |  |
| Income before income taxes | 7835 |  | 8841 |  |
| Provision for income taxes (e) | (703) |  | (1109) |  |
| Equity in earnings/(losses) of unconsolidated entities | (172) |  | (4) |  |
| Net income | 6960 |  | 7728 |  |
| Less: net income/(losses) attributable to noncontrolling interests and redeemable noncontrolling interest | 10 |  | 3 |  |
| Net income attributable to Thermo Fisher Scientific Inc. | $6950 | 15.5% | $7725 | 19.7% |
| Earnings per share attributable to Thermo Fisher Scientific Inc.: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $17.75 |  | $19.62 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $17.63 |  | $19.46 |  |
| Weighted average shares: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | 392 |  | 394 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | 394 |  | 397 |  |
| **Reconciliation of adjusted operating income and adjusted operating margin** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP operating income | $8393 | 18.7% | $10028 | 25.6% |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | 46 | 0.1% | 8 | 0.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | 37 | 0.1% | 144 | 0.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 114 | 0.3% | 197 | 0.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 2395 | 5.3% | 1761 | 4.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjusted operating income (non-GAAP measure) | $10985 | 24.5% | $12138 | 31.0% |
| **Reconciliation of adjusted net income** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP net income attributable to Thermo Fisher Scientific Inc. | $6950 |  | $7725 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | 46 |  | 8 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | 37 |  | 144 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 114 |  | 197 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 2395 |  | 1761 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income/expense adjustments (d) | 117 |  | 732 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Provision for income taxes adjustments (e) | (672) |  | (593) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Equity in earnings/losses of unconsolidated entities | 172 |  | 4 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjusted net income (non-GAAP measure) | $9159 |  | $9978 |  |
| **Reconciliation of adjusted earnings per share** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP diluted EPS attributable to Thermo Fisher Scientific Inc. | $17.63 |  | $19.46 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | 0.12 |  | 0.02 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | 0.09 |  | 0.36 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | 0.29 |  | 0.50 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | 6.07 |  | 4.43 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income/expense adjustments (d) | 0.30 |  | 1.84 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Provision for income taxes adjustments (e) | (1.70) |  | (1.49) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Equity in earnings/losses of unconsolidated entities | 0.44 |  | 0.01 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjusted EPS (non-GAAP measure) | $23.24 |  | $25.13 |  |
| **Reconciliation of free cash flow** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP net cash provided by operating activities | $9154 |  | $9312 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Purchases of property, plant and equipment | (2243) |  | (2523) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Proceeds from sale of property, plant and equipment | 24 |  | 20 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Free cash flow (non-GAAP measure) | $6935 |  | $6809 |  |

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| | | | | |
|:---|:---|:---|:---|:---|
| **Segment data** | Year ended | Year ended | Year ended | Year ended |
|  | December 31, | % of | December 31, | % of |
| (In millions) | 2022 | Revenues | 2021 | Revenues |
| **Revenues** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Life Sciences Solutions | $13532 | 30.1% | $15631 | 39.9% |
| &nbsp;&nbsp;&nbsp;&nbsp;Analytical Instruments | 6624 | 14.7% | 6069 | 15.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Specialty Diagnostics | 4763 | 10.6% | 5659 | 14.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Laboratory Products and Biopharma Services | 22511 | 50.1% | 14862 | 37.9% |
| &nbsp;&nbsp;&nbsp;&nbsp;Eliminations | (2515) | -5.5% | (3010) | -7.7% |
| &nbsp;&nbsp;&nbsp;&nbsp;Consolidated revenues | $44915 | 100.0% | $39211 | 100.0% |
| **Operating income and operating margin** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Life Sciences Solutions | $5582 | 41.2% | $7817 | 50.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Analytical Instruments | 1507 | 22.8% | 1197 | 19.7% |
| &nbsp;&nbsp;&nbsp;&nbsp;Specialty Diagnostics | 1024 | 21.5% | 1280 | 22.6% |
| &nbsp;&nbsp;&nbsp;&nbsp;Laboratory Products and Biopharma Services | 2872 | 12.8% | 1844 | 12.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Subtotal reportable segments | 10985 | 24.5% | 12138 | 31.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of revenues adjustments (a) | (46) | -0.1% | (8) | 0.0% |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative expenses adjustments (b) | (37) | -0.1% | (144) | -0.4% |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring and other costs (c) | (114) | -0.3% | (197) | -0.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of acquisition-related intangible assets | (2395) | -5.3% | (1761) | -4.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;GAAP operating income | $8393 | 18.7% | $10028 | 25.6% |
| (a) Adjusted results in 2022 and 2021 exclude charges for the sale of inventories revalued at the date of acquisition. Adjusted results in 2022 also exclude $27 of inventory write-downs associated with large-scale abandonment of product lines. | (a) Adjusted results in 2022 and 2021 exclude charges for the sale of inventories revalued at the date of acquisition. Adjusted results in 2022 also exclude $27 of inventory write-downs associated with large-scale abandonment of product lines. | (a) Adjusted results in 2022 and 2021 exclude charges for the sale of inventories revalued at the date of acquisition. Adjusted results in 2022 also exclude $27 of inventory write-downs associated with large-scale abandonment of product lines. | (a) Adjusted results in 2022 and 2021 exclude charges for the sale of inventories revalued at the date of acquisition. Adjusted results in 2022 also exclude $27 of inventory write-downs associated with large-scale abandonment of product lines. | (a) Adjusted results in 2022 and 2021 exclude charges for the sale of inventories revalued at the date of acquisition. Adjusted results in 2022 also exclude $27 of inventory write-downs associated with large-scale abandonment of product lines. |
| (b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | (b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | (b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | (b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. | (b) Adjusted results in 2022 and 2021 exclude certain third-party expenses, principally transaction/integration costs related to recent acquisitions, charges/credits for changes in estimates of contingent acquisition consideration, and charges associated with product liability litigation. |
| (c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $122 of charges for impairments of acquired intangible assets and $35 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | (c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $122 of charges for impairments of acquired intangible assets and $35 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | (c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $122 of charges for impairments of acquired intangible assets and $35 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | (c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $122 of charges for impairments of acquired intangible assets and $35 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. | (c) Adjusted results in 2022 and 2021 exclude restructuring and other costs consisting principally of severance, impairments of long-lived assets, charges/credits for environmental-related matters, abandoned facility and other expenses of headcount reductions within several businesses and real estate consolidations. Adjusted results in 2022 also exclude $14 of gain on the sale of intellectual property. Adjusted results in 2021 also exclude $122 of charges for impairments of acquired intangible assets and $35 of charges for compensation due to employees at recently acquired businesses at the date of acquisition. |
| (d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments and losses on the early extinguishment of debt. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $2 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $36 of charges for amortization of bridge loan commitment fees related to a pending acquisition. | (d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments and losses on the early extinguishment of debt. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $2 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $36 of charges for amortization of bridge loan commitment fees related to a pending acquisition. | (d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments and losses on the early extinguishment of debt. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $2 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $36 of charges for amortization of bridge loan commitment fees related to a pending acquisition. | (d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments and losses on the early extinguishment of debt. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $2 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $36 of charges for amortization of bridge loan commitment fees related to a pending acquisition. | (d) Adjusted results in 2022 and 2021 exclude net gains/losses on investments and losses on the early extinguishment of debt. Adjusted results in 2022 also exclude $67 of net gains on derivative instruments to address certain foreign currency risks and $2 of net settlement gains for pension plans. Adjusted results in 2021 also exclude $36 of charges for amortization of bridge loan commitment fees related to a pending acquisition. |
| (e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements (including a $658 benefit from an audit settlement in 2022). Adjusted results in 2022 also exclude a $423 charge for the impact of deferred tax realizability assessments as a result of audit settlements. | (e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements (including a $658 benefit from an audit settlement in 2022). Adjusted results in 2022 also exclude a $423 charge for the impact of deferred tax realizability assessments as a result of audit settlements. | (e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements (including a $658 benefit from an audit settlement in 2022). Adjusted results in 2022 also exclude a $423 charge for the impact of deferred tax realizability assessments as a result of audit settlements. | (e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements (including a $658 benefit from an audit settlement in 2022). Adjusted results in 2022 also exclude a $423 charge for the impact of deferred tax realizability assessments as a result of audit settlements. | (e) Adjusted provision for income taxes in 2022 and 2021 excludes incremental tax impacts for the reconciling items between GAAP and adjusted net income, incremental tax impacts as a result of tax rate/law changes and the tax impacts from audit settlements (including a $658 benefit from an audit settlement in 2022). Adjusted results in 2022 also exclude a $423 charge for the impact of deferred tax realizability assessments as a result of audit settlements. |
| Notes: | Notes: | Notes: | Notes: | Notes: |
| Consolidated depreciation expense is $986 and $831 in 2022 and 2021, respectively. | Consolidated depreciation expense is $986 and $831 in 2022 and 2021, respectively. | Consolidated depreciation expense is $986 and $831 in 2022 and 2021, respectively. | Consolidated depreciation expense is $986 and $831 in 2022 and 2021, respectively. | Consolidated depreciation expense is $986 and $831 in 2022 and 2021, respectively. |

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| | |
|:---|:---|
| **Organic and Core organic revenue growth** | Twelve months ended |
|  | December 31, 2022 |
| **Revenue growth** | 15% |
| Acquisitions | 18% |
| Currency translation | -3% |
| **Organic revenue growth** | 0% |
| COVID-19 testing revenue | -13% |
| Contribution of PPD to Core organic revenue growth (a) | 1% |
| **Core organic revenue growth** | 14% |
| (a) Adjustment to include the contribution of PPD to Core organic revenue growth as though the acquisition had occurred on January 1, 2021. | (a) Adjustment to include the contribution of PPD to Core organic revenue growth as though the acquisition had occurred on January 1, 2021. |
| Note: | Note: |
| For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. | For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. |

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---

| | | |
|:---|:---|:---|
| **Condensed Consolidated Balance Sheet (unaudited)** | | |
|  | December 31, | December 31, |
| (In millions) | 2022 | 2021 |
| **Assets** |  |  |
| Current assets: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cash and cash equivalents | $8524 | $4477 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accounts receivable, net | 8274 | 7977 |
| &nbsp;&nbsp;&nbsp;&nbsp;Inventories | 5634 | 5051 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other current assets | 2933 | 2608 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current assets | 25365 | 20113 |
| Property, plant and equipment, net | 9280 | 8333 |
| Acquisition-related intangible assets, net | 17442 | 20113 |
| Other assets | 4007 | 4640 |
| Goodwill | 41196 | 41924 |
| **Total assets** | $97290 | $95123 |
| **Liabilities, redeemable noncontrolling interest and equity** |  |  |
| Current liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Short-term obligations and current maturities of long-term obligations | $5579 | $2537 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other current liabilities | 11535 | 10899 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current liabilities | 17114 | 13436 |
| Other long-term liabilities | 7119 | 8377 |
| Long-term obligations | 28909 | 32333 |
| Redeemable noncontrolling interest | 116 | 122 |
| Total equity | 44032 | 40855 |
| **Total liabilities, redeemable noncontrolling interest and equity** | $97290 | $95123 |

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---

| | | |
|:---|:---|:---|
| **Condensed Consolidated Statement of Cash Flows (unaudited)** | | |
|  | Year ended | Year ended |
|  | December 31, | December 31, |
| (In millions) | 2022 | 2021 |
| **Operating activities** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Net income | $6960 | $7728 |
| &nbsp;&nbsp;&nbsp;&nbsp;Adjustments to reconcile net income to net cash provided by operating activities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Depreciation and amortization | 3381 | 2592 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Change in deferred income taxes | (995) | (647) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Other non-cash expenses, net | 857 | 1187 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Changes in assets and liabilities, excluding the effects of acquisitions | (1049) | (1548) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net cash provided by operating activities | 9154 | 9312 |
| **Investing activities** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Acquisitions, net of cash acquired | (39) | (19395) |
| &nbsp;&nbsp;&nbsp;&nbsp;Purchases of property, plant and equipment | (2243) | (2523) |
| &nbsp;&nbsp;&nbsp;&nbsp;Proceeds from sale of property, plant and equipment | 24 | 20 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other investing activities, net | 99 | (34) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net cash used in investing activities | (2159) | (21932) |
| **Financing activities** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Net proceeds from issuance of debt | 3193 | 18137 |
| &nbsp;&nbsp;&nbsp;&nbsp;Repayment of debt | (375) | (11738) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net proceeds from issuance of commercial paper | 1526 | 2512 |
| &nbsp;&nbsp;&nbsp;&nbsp;Repayment of commercial paper | (3690) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Purchases of company common stock | (3000) | (2000) |
| &nbsp;&nbsp;&nbsp;&nbsp;Dividends paid | (455) | (395) |
| &nbsp;&nbsp;&nbsp;&nbsp;Other financing activities, net | (9) | 65 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net cash (used in) provided by financing activities | (2810) | 6581 |
| Exchange rate effect on cash | (139) | 194 |
| Increase (decrease) in cash, cash equivalents and restricted cash | 4046 | (5845) |
| Cash, cash equivalents and restricted cash at beginning of period | 4491 | 10336 |
| Cash, cash equivalents and restricted cash at end of period | $8537 | $4491 |
| Free cash flow (non-GAAP measure) | $6935 | $6809 |
| Note: | Note: | Note: |
| For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. | For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. | For more information related to non-GAAP financial measures, refer to the section titled "Supplemental Information Regarding Non-GAAP Financial Measures" of this release. |

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**Supplemental Information Regarding Non-GAAP Financial Measures**

In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use certain non-GAAP financial measures such as organic revenue growth, which is reported revenue growth, excluding the impacts of revenues from acquired businesses and the effects of currency translation. We also report Core organic revenue growth, which is reported revenue growth including the impact of PPD revenue, excluding the impacts of COVID-19 testing revenue, and excluding the impacts of acquisitions other than PPD and currency translation. We calculate period-to-period Core organic revenue growth by adding to the baseline period PPD's pre-acquisition revenues from such period. We report these measures because Thermo Fisher management believes that in order to understand the company's short-term and long-term financial trends, investors may wish to consider the impact of acquisitions, foreign currency translation and/or COVID-19 testing on revenues. In particular, given PPD's significance relative to our existing businesses, management believes it is appropriate to also present information on a basis that includes PPD pre-acquisition revenues in order to demonstrate the impact PPD has on our current growth profile. Core organic revenue growth amounts are not necessarily indicative of the combined results of operations that would have been realized had the PPD acquisition occurred on January 1, 2021. Thermo Fisher management uses these measures to forecast and evaluate the operational performance of the company as well as to compare revenues of current periods to prior periods.

We report adjusted operating income, adjusted operating income margin, adjusted net income, and adjusted EPS. We believe that the use of these non-GAAP financial measures, in addition to GAAP financial measures, helps investors to gain a better understanding of our core operating results and future prospects, consistent with how management measures and forecasts the company's core operating performance, especially when comparing such results to previous periods, forecasts, and to the performance of our competitors. Such measures are also used by management in their financial and operating decision-making and for compensation purposes. To calculate these measures we exclude, as applicable:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Certain acquisition-related costs, including charges for the sale of inventories revalued at the date of acquisition, significant transaction/acquisition-related costs, including changes in estimates of contingent acquisition-related consideration, and other costs associated with obtaining short-term financing commitments for pending/recent acquisitions. We exclude these costs because we do not believe they are indicative of our normal operating costs.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Costs/income associated with restructuring activities and large-scale abandonments of product lines, such as reducing overhead and consolidating facilities. We exclude these costs because we believe that the costs related to restructuring activities are not indicative of our normal operating costs.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Equity in earnings/losses of unconsolidated entities; impairments of long-lived assets; and certain other gains and losses that are either isolated or cannot be expected to occur again with any predictability, including gains/losses on investments, the sale of businesses, product lines, and real estate, significant litigation-related matters, curtailments/settlements of pension plans, and the early retirement of debt. We exclude these items because they are outside of our normal operations and/or, in certain cases, are difficult to forecast accurately for future periods.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The expense associated with the amortization of acquisition-related intangible assets because a significant portion of the purchase price for acquisitions may be allocated to intangible assets that have lives of up to 20 years. Exclusion of the amortization expense allows comparisons of operating results that are consistent over time for both our newly acquired and long-held businesses and with both acquisitive and non-acquisitive peer companies.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The tax impacts of the above items and the impact of significant tax audits or events (such as changes in deferred taxes from enacted tax rate/law changes), the latter of which we exclude because they are outside of our normal operations and difficult to forecast accurately for future periods.

We report free cash flow, which is operating cash flow excluding net capital expenditures, to provide a view of the continuing operations' ability to generate cash for use in acquisitions and other investing and financing activities. The company also uses this measure as an indication of the strength of the company. Free cash flow is not a measure of cash available for discretionary expenditures since we have certain non-discretionary obligations such as debt service that are not deducted from the measure.

Thermo Fisher Scientific does not provide GAAP financial measures on a forward-looking basis because we are unable to predict with reasonable certainty and without unreasonable effort items such as the timing and amount of future restructuring actions and acquisition-related charges as well as gains or losses from sales of real estate and businesses, the early retirement of debt and the outcome of legal proceedings. The timing and amount of these items are uncertain and could be material to Thermo Fisher Scientific's results computed in accordance with GAAP.

The non-GAAP financial measures of Thermo Fisher Scientific's results of operations and cash flows included in this press release are not meant to be considered superior to or a substitute for Thermo Fisher Scientific's results of operations prepared in accordance with GAAP. Reconciliations of such non-GAAP financial measures to the most directly comparable GAAP financial measures are set forth in the tables above.

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