# EDGAR Filing Document

**Accession Number:** 0001559109
**File Stem:** 0000940400-25-014936
**Filing Date:** 2025-12
**Character Count:** 38704
**Document Hash:** 465d3556c54d637f37b399b21dde12fb
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000940400-25-014936.hdr.sgml**: 20251229

**ACCESSION NUMBER**: 0000940400-25-014936

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20251031

**FILED AS OF DATE**: 20251229

**DATE AS OF CHANGE**: 20251229

**PERIOD START**: 20251031

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ETFis Series Trust I
- **CENTRAL INDEX KEY:** 0001559109

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1031

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-22819
- **FILM NUMBER:** 251606210

**BUSINESS ADDRESS:**
- **STREET 1:** 1301 AVENUE OF THE AMERICAS
- **STREET 2:** 16TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019
- **BUSINESS PHONE:** 2125934383

**MAIL ADDRESS:**
- **STREET 1:** 1301 AVENUE OF THE AMERICAS
- **STREET 2:** 16TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ETF Actively Managed Trust
- **DATE OF NAME CHANGE:** 20120926

## Series and Classes Contracts Data

### Virtus LifeSci Biotech Clinical Trials ETF (Series ID: S000047353)

| Class ID   | Class Name                                 | Ticker Symbol   |
|:---|:---|:---|
| C000148681 | Virtus LifeSci Biotech Clinical Trials ETF | BBC             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ETFis Series Trust I

- **b. Investment Company Act file number:** 811-22819

- **c. CIK number of Registrant:** 0001559109

- **d. LEI of Registrant:** 5493002CWTVLBPSYFT98

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 1301 Avenue of the Americas

  - **City:** New York

  - **State:** NY

  - **Foreign country:** US

  - **Zip / Postal Code:** 10019

  - **Telephone number:** 1-888-383-0553

**Item A.2. Information about the Series.**

- **a. Name of Series:** Virtus LifeSci Biotech Clinical Trials ETF

- **b. EDGAR series identifier (if any):** S000047353

- **c. LEI of Series:** 549300YTBZ16PIXEKJ82

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-10-31

- **b. Date as of which information is reported:** 2025-10-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $23442381.56

**Total Liabilities:** $2454736.07

**Net Assets:** $20987645.49

**Cash Not Reported:** $139032.03

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000148681 | 5.08%                | 20.38%               | 17.97%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $16556.16                | $760035.00                                 |
| Month 2  | $276545.98               | $2769993.14                                |
| Month 3  | $395992.61               | $2809979.51                                |

### Schedule of Portfolio Investments

| Name                           | Title                              | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Monte Rosa Therapeutics Inc    | Monte Rosa Therapeutics Inc        | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     24285 | NS      | $312062.25    | 1.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Vaxcyte Inc                    | Vaxcyte Inc                        | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |      3467 | NS      | $156985.76    | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| AbCellera Biologics Inc        | AbCellera Biologics Inc            | CUSIP: 00288U106<br>LEI: 9845000861BC95FF9F73 | Long             | EC               | CORP              | CA        |     37931 | NS      | $210517.05    | 1.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Cytokinetics Inc               | Cytokinetics Inc                   | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |      3599 | NS      | $228860.41    | 1.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Tectonic Therapeutic Inc       | Tectonic Therapeutic Inc           | CUSIP: 878972108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5325 | NS      | $97181.25     | 0.46%             |  |  |  | No            |                  1 | On Loan: —       |
| ORIC Pharmaceuticals Inc       | ORIC Pharmaceuticals Inc           | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |     12356 | NS      | $162604.96    | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicycle Therapeutics PLC       | Bicycle Therapeutics PLC           | CUSIP: 088786108<br>LEI: 213800XKUI6R7GKC3E43 | Long             | EC               | CORP              | GB        |     13749 | NS      | $110954.43    | 0.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc         | Sana Biotechnology Inc             | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     47040 | NS      | $232848.00    | 1.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Arrowhead Pharmaceuticals Inc  | Arrowhead Pharmaceuticals Inc      | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |      7366 | NS      | $312244.74    | 1.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc         | Stoke Therapeutics Inc             | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |     10108 | NS      | $303644.32    | 1.45%             |  |  |  | No            |                  1 | On Loan: No      |
| CureVac NV                     | CureVac NV                         | CUSIP: 000000000<br>LEI: 724500BUT8GAG9LMYN56 | Long             | EC               | CORP              | DE        |     21336 | NS      | $113934.24    | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon Inc                    | Annexon Inc                        | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     44089 | NS      | $139321.24    | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcus Biosciences Inc          | Arcus Biosciences Inc              | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12779 | NS      | $252001.88    | 1.20%             |  |  |  | No            |                  1 | On Loan: —       |
| Immatics NV                    | Immatics NV                        | CUSIP: 000000000<br>LEI: 984500DC691EZ96AF394 | Long             | EC               | CORP              | DE        |     19460 | NS      | $198297.40    | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara Inc                     | Savara Inc                         | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |     52868 | NS      | $219402.20    | 1.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Astria Therapeutics Inc        | Astria Therapeutics Inc            | CUSIP: 04635X102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     21336 | NS      | $269473.68    | 1.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcellx Inc                    | Arcellx Inc                        | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1796 | NS      | $162089.00    | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Structure Therapeutics Inc     | Structure Therapeutics Inc         | CUSIP: 86366E106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5377 | NS      | $179161.64    | 0.85%             |  |  |  | No            |                  1 | On Loan: —       |
| Edgewise Therapeutics Inc      | Edgewise Therapeutics Inc          | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7749 | NS      | $141651.72    | 0.67%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc        | Apogee Therapeutics Inc            | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2854 | NS      | $161507.86    | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcturus Therapeutics Holdings | Arcturus Therapeutics Holdings Inc | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9453 | NS      | $94246.41     | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc     | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2653 | NS      | $527310.28    | 2.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                   | Biohaven Ltd                       | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7664 | NS      | $131820.80    | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Celcuity Inc                   | Celcuity Inc                       | CUSIP: 15102K100<br>LEI: 25490070W7UU7W2SEY87 | Long             | EC               | CORP              | US        |      9513 | NS      | $734023.08    | 3.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvalent Inc                   | Nuvalent Inc                       | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1534 | NS      | $152356.88    | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Revolution Medicines Inc       | Revolution Medicines Inc           | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |      2906 | NS      | $170989.04    | 0.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Keros Therapeutics Inc         | Keros Therapeutics Inc             | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8760 | NS      | $133327.20    | 0.64%             |  |  |  | No            |                  1 | On Loan: —       |
| Soleno Therapeutics Inc        | Soleno Therapeutics Inc            | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |      1490 | NS      | $100068.40    | 0.48%             |  |  |  | No            |                  1 | On Loan: No      |
| ArriVent Biopharma Inc         | ArriVent Biopharma Inc             | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5056 | NS      | $94698.88     | 0.45%             |  |  |  | No            |                  1 | On Loan: —       |
| Disc Medicine Inc              | Disc Medicine Inc                  | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2267 | NS      | $195460.74    | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunome Inc                   | Immunome Inc                       | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12205 | NS      | $196134.35    | 0.93%             |  |  |  | No            |                  1 | On Loan: —       |
| Beam Therapeutics Inc          | Beam Therapeutics Inc              | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6851 | NS      | $171343.51    | 0.82%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc       | Enliven Therapeutics Inc           | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6077 | NS      | $142323.34    | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp         | Arbutus Biopharma Corp             | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | US        |     33375 | NS      | $157863.75    | 0.75%             |  |  |  | No            |                  1 | On Loan: —       |
| Liquidia Corp                  | Liquidia Corp                      | CUSIP: 53635D202<br>LEI: 549300O826O5VQJTG707 | Long             | EC               | CORP              | US        |      8269 | NS      | $201432.84    | 0.96%             |  |  |  | No            |                  1 | On Loan: —       |
| Vera Therapeutics Inc          | Vera Therapeutics Inc              | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5306 | NS      | $151008.76    | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics Inc         | Tango Therapeutics Inc             | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23660 | NS      | $191882.60    | 0.91%             |  |  |  | No            |                  1 | On Loan: —       |
| Prothena Corp PLC              | Prothena Corp PLC                  | CUSIP: 000000000<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | IE        |     23567 | NS      | $253345.25    | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Recursion Pharmaceuticals Inc  | Recursion Pharmaceuticals Inc      | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23111 | NS      | $127572.72    | 0.61%             |  |  |  | No            |                  1 | On Loan: —       |
| Rapport Therapeutics Inc       | Rapport Therapeutics Inc           | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10726 | NS      | $310303.18    | 1.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Tyra Biosciences Inc           | Tyra Biosciences Inc               | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11567 | NS      | $183221.28    | 0.87%             |  |  |  | No            |                  1 | On Loan: No      |
| uniQure NV                     | uniQure NV                         | CUSIP: 000000000<br>LEI: 724500RPCTZLFYJZ3S98 | Long             | EC               | CORP              | NL        |      7472 | NS      | $505779.68    | 2.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc   | Protagonist Therapeutics Inc       | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2121 | NS      | $166753.02    | 0.79%             |  |  |  | No            |                  1 | On Loan: No      |
| Silence Therapeutics PLC       | Silence Therapeutics PLC           | CUSIP: 82686Q101<br>LEI: 213800SSURRJBX85SQ91 | Long             | EC               | CORP              | GB        |     21393 | NS      | $153173.88    | 0.73%             |  |  |  | No            |                  1 | On Loan: —       |
| Cullinan Therapeutics Inc      | Cullinan Therapeutics Inc          | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13350 | NS      | $115611.00    | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| Maze Therapeutics Inc          | Maze Therapeutics Inc              | CUSIP: 578784100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8818 | NS      | $290200.38    | 1.38%             |  |  |  | No            |                  1 | On Loan: No      |
| WaVe Life Sciences Ltd         | WaVe Life Sciences Ltd             | CUSIP: 000000000<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | US        |     16595 | NS      | $150018.80    | 0.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Sionna Therapeutics Inc        | Sionna Therapeutics Inc            | CUSIP: 829401108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7033 | NS      | $268730.93    | 1.28%             |  |  |  | No            |                  1 | On Loan: —       |
| Janux Therapeutics Inc         | Janux Therapeutics Inc             | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4675 | NS      | $134219.25    | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Pharvaris NV                   | Pharvaris NV                       | CUSIP: 000000000<br>LEI: 9845003BE146D3B75D32 | Long             | EC               | CORP              | NL        |      6935 | NS      | $154095.70    | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Avidity Biosciences Inc        | Avidity Biosciences Inc            | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3718 | NS      | $259702.30    | 1.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Corvus Pharmaceuticals Inc     | Corvus Pharmaceuticals Inc         | CUSIP: 221015100<br>LEI: 549300I3AVJ8F75NCX65 | Long             | EC               | CORP              | US        |     28180 | NS      | $226567.20    | 1.08%             |  |  |  | No            |                  1 | On Loan: —       |
| Xencor Inc                     | Xencor Inc                         | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |     12670 | NS      | $186375.70    | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Rocket Pharmaceuticals Inc     | Rocket Pharmaceuticals Inc         | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |     38919 | NS      | $146724.63    | 0.70%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc        | Denali Therapeutics Inc            | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |      8006 | NS      | $130337.68    | 0.62%             |  |  |  | No            |                  1 | On Loan: —       |
| Arvinas Inc                    | Arvinas Inc                        | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     15784 | NS      | $160049.76    | 0.76%             |  |  |  | No            |                  1 | On Loan: No      |
| GH Research PLC                | GH Research PLC                    | CUSIP: 000000000<br>LEI: 875500HKJS7QQG6EWH62 | Long             | EC               | CORP              | IE        |      9313 | NS      | $133362.16    | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Belite Bio Inc                 | Belite Bio Inc                     | CUSIP: 07782B104<br>LEI: 984500BD54036BOEAE79 | Long             | EC               | CORP              | US        |      1923 | NS      | $203655.32    | 0.97%             |  |  |  | No            |                  1 | On Loan: —       |
| Erasca Inc                     | Erasca Inc                         | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     78093 | NS      | $188985.06    | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc                  | Altimmune Inc                      | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |     16711 | NS      | $67679.55     | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Summit Therapeutics Inc        | Summit Therapeutics Inc            | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5927 | NS      | $112079.57    | 0.53%             |  |  |  | No            |                  1 | On Loan: —       |
| MoonLake Immunotherapeutics    | MoonLake Immunotherapeutics        | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | CH        |      2714 | NS      | $27411.40     | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| CG oncology Inc                | CG oncology Inc                    | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4509 | NS      | $195104.43    | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Mind Medicine MindMed Inc      | Mind Medicine MindMed Inc          | CUSIP: 60255C885<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | US        |     16367 | NS      | $232411.40    | 1.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences Inc         | Cogent Biosciences Inc             | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     16549 | NS      | $269748.70    | 1.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Ideaya Biosciences Inc         | Ideaya Biosciences Inc             | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |      5363 | NS      | $170865.18    | 0.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc   | Xeris Biopharma Holdings Inc       | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     27032 | NS      | $262210.40    | 1.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Xenon Pharmaceuticals Inc      | Xenon Pharmaceuticals Inc          | CUSIP: 98420N105<br>LEI: 549300XV44Q9Z1MIPQ03 | Long             | EC               | CORP              | CA        |      3643 | NS      | $152714.56    | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Olema Pharmaceuticals Inc      | Olema Pharmaceuticals Inc          | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     29429 | NS      | $263978.13    | 1.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Centessa Pharmaceuticals PLC   | Centessa Pharmaceuticals PLC       | CUSIP: 152309100<br>LEI: 213800GIDAARDSKOI827 | Long             | EC               | CORP              | US        |      9924 | NS      | $247107.60    | 1.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Entrada Therapeutics Inc       | Entrada Therapeutics Inc           | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     15221 | NS      | $105785.95    | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Terns Pharmaceuticals Inc      | Terns Pharmaceuticals Inc          | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |     30403 | NS      | $251128.78    | 1.20%             |  |  |  | No            |                  1 | On Loan: —       |
| Nuvation Bio Inc               | Nuvation Bio Inc                   | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     66012 | NS      | $344582.64    | 1.64%             |  |  |  | No            |                  1 | On Loan: —       |
| Arcutis Biotherapeutics Inc    | Arcutis Biotherapeutics Inc        | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8851 | NS      | $224018.81    | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc         | Relay Therapeutics Inc             | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     34633 | NS      | $247279.62    | 1.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Crinetics Pharmaceuticals Inc  | Crinetics Pharmaceuticals Inc      | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |      3714 | NS      | $161559.00    | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurogene Inc                  | Neurogene Inc                      | CUSIP: 64135M105<br>LEI: 529900A7VIY892SZVW73 | Long             | EC               | CORP              | US        |      5857 | NS      | $200660.82    | 0.96%             |  |  |  | No            |                  1 | On Loan: —       |
| Viridian Therapeutics Inc      | Viridian Therapeutics Inc          | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |      7625 | NS      | $180178.75    | 0.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp      | Scholar Rock Holding Corp          | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |      3586 | NS      | $106217.32    | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Zymeworks Inc                  | Zymeworks Inc                      | CUSIP: 98985Y108<br>LEI: 894500AHOYAGYLYZJL67 | Long             | EC               | CORP              | US        |      9121 | NS      | $174074.29    | 0.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology Inc              | Kura Oncology Inc                  | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |     17940 | NS      | $184243.80    | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc      | Dianthus Therapeutics Inc          | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |      6194 | NS      | $216666.12    | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Viking Therapeutics Inc        | Viking Therapeutics Inc            | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |      4181 | NS      | $159212.48    | 0.76%             |  |  |  | No            |                  1 | On Loan: —       |
| Nurix Therapeutics Inc         | Nurix Therapeutics Inc             | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9990 | NS      | $129270.60    | 0.62%             |  |  |  | No            |                  1 | On Loan: No      |
| REGENXBIO Inc                  | REGENXBIO Inc                      | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |     11714 | NS      | $149587.78    | 0.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Capricor Therapeutics Inc      | Capricor Therapeutics Inc          | CUSIP: 14070B309<br>LEI: 5493002ZI5PDLXV4DX14 | Long             | EC               | CORP              | US        |      8571 | NS      | $55797.21     | 0.27%             |  |  |  | No            |                  1 | On Loan: —       |
| Autolus Therapeutics PLC       | Autolus Therapeutics PLC           | CUSIP: 05280R100<br>LEI: 549300C0KZP8EYROLL02 | Long             | EC               | CORP              | GB        |     55573 | NS      | $86138.15     | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Mineralys Therapeutics Inc     | Mineralys Therapeutics Inc         | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8008 | NS      | $327206.88    | 1.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Mereo Biopharma Group PLC      | Mereo Biopharma Group PLC          | CUSIP: 589492107<br>LEI: 213800U8JQHIJOS5AS09 | Long             | EC               | CORP              | GB        |     42979 | NS      | $81660.10     | 0.39%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc      | Intellia Therapeutics Inc          | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |     14309 | NS      | $180579.58    | 0.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Compass Pathways Plc           | Compass Pathways Plc               | CUSIP: 20451W101<br>LEI: 213800N7CUZIC6QSTZ31 | Long             | EC               | CORP              | GB        |     26434 | NS      | $167062.88    | 0.80%             |  |  |  | No            |                  1 | On Loan: —       |
| Celldex Therapeutics Inc       | Celldex Therapeutics Inc           | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |      5871 | NS      | $156931.83    | 0.75%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals Inc   | KalVista Pharmaceuticals Inc       | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |      9128 | NS      | $99586.48     | 0.47%             |  |  |  | No            |                  1 | On Loan: —       |
| Spyre Therapeutics Inc         | Spyre Therapeutics Inc             | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |      6747 | NS      | $165031.62    | 0.79%             |  |  |  | No            |                  1 | On Loan: —       |
| Taysha Gene Therapies Inc      | Taysha Gene Therapies Inc          | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45088 | NS      | $223636.48    | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Vir Biotechnology Inc          | Vir Biotechnology Inc              | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22889 | NS      | $136418.44    | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| AnaptysBio Inc                 | AnaptysBio Inc                     | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |      5104 | NS      | $186704.32    | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Dyne Therapeutics Inc          | Dyne Therapeutics Inc              | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8263 | NS      | $186578.54    | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant Inc                 | Immunovant Inc                     | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7496 | NS      | $185001.28    | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc        | Kymera Therapeutics Inc            | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2527 | NS      | $156269.68    | 0.74%             |  |  |  | No            |                  1 | On Loan: No      |
| LENZ Therapeutics Inc          | LENZ Therapeutics Inc              | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4039 | NS      | $120039.08    | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| NEWAMSTERDAM PHARMA CO NV      | NEWAMSTERDAM PHARMA CO NV-27       | CUSIP: 000000000<br>LEI: 984500B6549TF6E14D36 | Long             | EC               | CORP              | NL        |      5682 | NS      | $215631.90    | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicara Therapeutics Inc        | Bicara Therapeutics Inc            | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10327 | NS      | $167813.75    | 0.80%             |  |  |  | No            |                  1 | On Loan: —       |
| MBX Biosciences Inc            | MBX Biosciences Inc                | CUSIP: 55287L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11146 | NS      | $244766.16    | 1.17%             |  |  |  | No            |                  1 | On Loan: —       |
| Syndax Pharmaceuticals Inc     | Syndax Pharmaceuticals Inc         | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |     11198 | NS      | $153412.60    | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Allogene Therapeutics Inc      | Allogene Therapeutics Inc          | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     85345 | NS      | $105827.80    | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc            | Replimune Group Inc                | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |     12087 | NS      | $117606.51    | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| DREYFUS GOVERNMENT CASH MANAGE | DREYFUS GOVERNMENT CASH MANAGE     | CUSIP: 000000000<br>LEI: N/A                  | Long             | STIV             | RF                | US        |   2442090 | NS      | $2442090.50   | 11.64%            |  |  |  | No            |                  1 | On Loan: No      |
| EyePoint Pharmaceuticals Inc   | EyePoint Pharmaceuticals Inc       | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |     13486 | NS      | $176531.74    | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| Cartesian Therapeutics Inc     | Cartesian Therapeutics Inc         | CUSIP: 816212302<br>LEI: 529900NMN0LACZOL7C43 | Long             | EC               | CORP              | US        |     11668 | NS      | $95327.56     | 0.45%             |  |  |  | No            |                  1 | On Loan: —       |
| Upstream Bio Inc               | Upstream Bio Inc                   | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10336 | NS      | $267185.60    | 1.27%             |  |  |  | No            |                  1 | On Loan: —       |

### Signature

**Date Signed:** 2025-12-26

**Name of Applicant:** ETFis Series Trust I

**Signature:** Brinton W. Frith

**Name of Signer:** Brinton W. Frith

**Title:** Treasurer and Principal Financial Officer