# EDGAR Filing Document

**Accession Number:** 0000834365
**File Stem:** 0000919574-25-003574
**Filing Date:** 2025-6
**Character Count:** 16815
**Document Hash:** 8b0666406528b47b590d84accfdf37ae
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000919574-25-003574.hdr.sgml**: 20250612

**ACCESSION NUMBER**: 0000919574-25-003574

**CONFORMED SUBMISSION TYPE**: SCHEDULE 13D/A

**PUBLIC DOCUMENT COUNT**: 3

**FILED AS OF DATE**: 20250612

**DATE AS OF CHANGE**: 20250612

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** BIOLIFE SOLUTIONS INC
- **CENTRAL INDEX KEY:** 0000834365
- **STANDARD INDUSTRIAL CLASSIFICATION:** ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 943076866
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13D/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-40587
- **FILM NUMBER:** 251044571

**BUSINESS ADDRESS:**
- **STREET 1:** 3303 MONTE VILLA PARKWAY
- **STREET 2:** SUITE 310
- **CITY:** BOTHELL
- **STATE:** WA
- **ZIP:** 98021
- **BUSINESS PHONE:** 4254011400

**MAIL ADDRESS:**
- **STREET 1:** 3303 MONTE VILLA PARKWAY
- **STREET 2:** SUITE 310
- **CITY:** BOTHELL
- **STATE:** WA
- **ZIP:** 98021

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** BIOLIFE SOLUTION INC
- **DATE OF NAME CHANGE:** 20030113

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CRYOMEDICAL SCIENCES INC
- **DATE OF NAME CHANGE:** 19920703
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Casdin Capital, LLC
- **CENTRAL INDEX KEY:** 0001534261

**ORGANIZATION NAME:**
- **EIN:** 800752351
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13D/A

**BUSINESS ADDRESS:**
- **STREET 1:** 1350 AVENUE OF THE AMERICAS
- **STREET 2:** SUITE 2600
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019
- **BUSINESS PHONE:** 212.300.5575

**MAIL ADDRESS:**
- **STREET 1:** 1350 AVENUE OF THE AMERICAS
- **STREET 2:** SUITE 2600
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019

## Ex-99

Exhibit A

<u>AGREEMENT</u>

The undersigned agree that this Schedule 13D amendment, dated June 12, 2025, relating to the Common Stock, par value $0.001 per share of BioLife Solutions, Inc. shall be filed on behalf of the undersigned.

<u>June 12, 2025</u> <br> (Date)

---

| |
|:---|
| &nbsp;&nbsp; Casdin Capital, LLC<br>By: /s/ Eli Casdin |
| &nbsp;&nbsp;(Signature) |
| &nbsp;&nbsp;Eli Casdin, Managing Member |
| &nbsp;&nbsp;(Name/Title) |

---

---

| |
|:---|
| &nbsp;&nbsp; Casdin Partners Master Fund, L.P.<br>By: /s/ Eli Casdin |
| &nbsp;&nbsp;(Signature) |
| &nbsp;&nbsp;Eli Casdin, Managing Member of its General Partner |
| &nbsp;&nbsp;(Name/Title) |

---

---

| |
|:---|
| &nbsp;&nbsp; Casdin Partners GP, LLC<br>By: /s/ Eli Casdin |
| &nbsp;&nbsp;(Signature) |
| &nbsp;&nbsp;Eli Casdin, Managing Member |
| &nbsp;&nbsp;(Name/Title) |
| &nbsp;&nbsp;/s/ Eli Casdin |
| &nbsp;&nbsp;Eli Casdin |

---

## Ex-99

Exhibit B

**Schedule of Transactions in Shares**

---

| | | | | |
|:---|:---|:---|:---|:---|
| &nbsp;&nbsp; <br> <u>Date of Transaction</u> | &nbsp;&nbsp; <br> <u>Title of Class</u> | &nbsp;&nbsp;<u>Number of Shares Acquired</u> | &nbsp;&nbsp;<u>Number of Shares Disposed</u> | &nbsp;&nbsp; <u>Price Per Share</u><br>|
| &nbsp;&nbsp;June 10, 2025 | &nbsp;&nbsp;Common Stock, par value $0.001 per share |  | &nbsp;&nbsp;1000000 | &nbsp;&nbsp;$23.80 |

---

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## SCHEDULE 13D

### Under the Securities Exchange Act of 1934

**(Amendment No. 3)**

**BioLife Solutions, Inc.**

*(Name of Issuer)*

**Common Stock, par value $0.001 per share**

*(Title of Class of Securities)*

**09062W204**

*(CUSIP Number)*

**Eli Casdin**<br>Casdin Capital, LLC<br>1350 Avenue of the Americas, Suite 2405<br>New York NY 10019<br>(212) 897-5438

*(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)*

**06/10/2025**

*(Date of Event Which Requires Filing of this Statement)*

| **CUSIP No.** | **09062W204** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Casdin Capital, LLC** | Name of reporting person<br>**Casdin Capital, LLC** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**AF** | Source of funds (See Instructions)<br>**AF** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**DELAWARE** | Citizenship or place of organization<br>**DELAWARE** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**7707165.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**7707165.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**16.2%** | Percent of class represented by amount in Row (11)<br>**16.2%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**IA** | Type of Reporting Person (See Instructions)<br>**IA** | |

---

| **CUSIP No.** | **09062W204** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Casdin Partners Master Fund, L.P.** | Name of reporting person<br>**Casdin Partners Master Fund, L.P.** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**WC** | Source of funds (See Instructions)<br>**WC** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**CAYMAN ISLANDS** | Citizenship or place of organization<br>**CAYMAN ISLANDS** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**7707165.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**7707165.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**16.2%** | Percent of class represented by amount in Row (11)<br>**16.2%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**PN** | Type of Reporting Person (See Instructions)<br>**PN** | |

---

| **CUSIP No.** | **09062W204** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Casdin Partners GP, LLC** | Name of reporting person<br>**Casdin Partners GP, LLC** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**AF** | Source of funds (See Instructions)<br>**AF** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**DELAWARE** | Citizenship or place of organization<br>**DELAWARE** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**7707165.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**7707165.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**16.2%** | Percent of class represented by amount in Row (11)<br>**16.2%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**OO** | Type of Reporting Person (See Instructions)<br>**OO** | |

---

| **CUSIP No.** | **09062W204** |

---

| | | | |
|:--|:--|:--|:--|
| 1 | Name of reporting person<br>**Eli Casdin** | Name of reporting person<br>**Eli Casdin** | |
| 2 | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | Check the appropriate box if a member of a Group (See Instructions)<br>[x] (a)<br>[ ] (b) | |
| 3 | SEC use only | SEC use only | |
| 4 | Source of funds (See Instructions)<br>**AF** | Source of funds (See Instructions)<br>**AF** | |
| 5 | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)<br>[ ] | |
| 6 | Citizenship or place of organization<br>**X1** | Citizenship or place of organization<br>**X1** | |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 7 | Sole Voting Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 8 | Shared Voting Power<br>**7707165.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 9 | Sole Dispositive Power<br>**0.00** |
| Number of Shares<br>Beneficially Owned by<br>Each Reporting Person With: | 10 | Shared Dispositive Power<br>**7707165.00** |
| 11 | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | Aggregate amount beneficially owned by each reporting person<br>**7707165.00** | |
| 12 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)<br>[ ] | |
| 13 | Percent of class represented by amount in Row (11)<br>**16.2%** | Percent of class represented by amount in Row (11)<br>**16.2%** | |
| 14 | Type of Reporting Person (See Instructions)<br>**IN** | Type of Reporting Person (See Instructions)<br>**IN** | |

---

**Item 1. Security and Issuer**

**(a) Title of Class of Securities:**
Common Stock, par value $0.001 per share

**(b) Name of Issuer:**
BioLife Solutions, Inc.

**(c) Address of Issuer's Principal Executive Offices:**
3303 Monte Villa Parkway, Suite 310, Bothell, WA, 98021

**Item 4. Purpose of Transaction**

The Reporting Persons have acquired their Shares of the Issuer for investment.  The Reporting Persons have no plans or proposals as of the date of this filing which, other than as expressly set forth below, would relate to or would result in: (a) any extraordinary corporate transaction involving the Issuer; (b) any change in the present Board of Directors or management of the Issuer; (c) any material change in the present capitalization or dividend policy of the Issuer; (d) any material change in the operating policies or corporate structure of the Issuer; (e) any change in the Issuer's charter or by-laws; (f) the Shares of the Issuer ceasing to be listed from a national securities exchange or to ceasing to be authorized to be quoted in an inter-dealer quotation system of a registered national securities association; or (g) causing the Issuer becoming eligible for termination of registration pursuant to Section 12(g)(4) of the Securities Exchange Act of 1934.

The Reporting Persons, however, reserve the right, at a later date, to effect one or more of such changes and may dispose of or enter into other transactions in the shares they may be deemed to beneficially own.

The Reporting Persons have been and may continue to be in contact with members of the Issuer's management, the Issuer's Board of Directors, other significant shareholders and others regarding alternatives that the Issuer could employ to maximize shareholder value.

The Reporting Persons further reserve the right to act in concert with any other shareholders of the Issuer, or other persons, for a common purpose should it determine to do so, and/or to recommend courses of action to management and the shareholders of the Issuer.

**Item 5. Interest in Securities of the Issuer**

**(a)**
(a) - (e) As of the date hereof, Casdin, the Fund, the GP and Eli Casdin may be deemed to be the beneficial owners of 7,707,165 Shares, constituting 16.2% of the Shares based upon 47,561,171* Shares outstanding.

Casdin has the sole power to vote or direct the vote of 0 Shares; has the shared power to vote or direct the vote of 7,707,165 Shares; has the sole power to dispose or direct the disposition of 0 Shares; and has the shared power to dispose or direct the disposition of 7,707,165 Shares.

The Fund has the sole power to vote or direct the vote of 0 Shares; has the shared power to vote or direct the vote of 7,707,165 Shares; has the sole power to dispose or direct the disposition of 0 Shares; and has the shared power to dispose or direct the disposition of 7,707,165 Shares.

The GP has the sole power to vote or direct the vote of 0 Shares; has the shared power to vote or direct the vote of 7,707,165 Shares; has the sole power to dispose or direct the disposition of 0 Shares; and has the shared power to dispose or direct the disposition of 7,707,165 Shares.

Eli Casdin has the sole power to vote or direct the vote of 0 Shares; has the shared power to vote or direct the vote of 7,707,165 Shares; has the sole power to dispose or direct the disposition of 0 Shares; and has the shared power to dispose or direct the disposition of 7,707,165 Shares.

The transactions by the Reporting Persons in the Shares are set forth in Exhibit B.

*This outstanding Shares figure reflects the number of outstanding Shares as of May 1, 2025.

**(b)**
—

**(c)**
—

**Item 6. Contracts, Arrangements, Understandings or Relationships With Respect to Securities of the Issuer.**

Not Applicable.

### SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Casdin Capital, LLC

**Signature:** By /s/ Eli Casdin*

**Name/Title:** Eli Casdin, Managing Member

**Date:** 06/12/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Casdin Partners Master Fund, L.P.

**Signature:** By: /s/ Eli Casdin*

**Name/Title:** Eli Casdin, Managing Member of its General Partner

**Date:** 06/12/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Casdin Partners GP, LLC

**Signature:** By /s/ Eli Casdin*

**Name/Title:** Eli Casdin, Managing Member

**Date:** 06/12/2025

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Reporting Person:** Eli Casdin

**Signature:** By /s/ Eli Casdin*

**Name/Title:** Eli Casdin

**Date:** 06/12/2025