# EDGAR Filing Document

**Accession Number:** 0001815776
**File Stem:** 0001642575-26-000004
**Filing Date:** 2026-4
**Character Count:** 19750
**Document Hash:** 9f4c4bf48c0f64926159ba4c2da2f479
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001642575-26-000004.hdr.sgml**: 20260408

**ACCESSION NUMBER**: 0001642575-26-000004

**CONFORMED SUBMISSION TYPE**: SCHEDULE 13G

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20260408

**DATE AS OF CHANGE**: 20260408

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** LENZ Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001815776
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 844867570
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-92660
- **FILM NUMBER:** 26847754

**BUSINESS ADDRESS:**
- **STREET 1:** 201 LOMAS SANTA FE DRIVE, SUITE 300
- **CITY:** SOLANA BEACH
- **STATE:** CA
- **ZIP:** 92075
- **BUSINESS PHONE:** 858-925-7000

**MAIL ADDRESS:**
- **STREET 1:** 201 LOMAS SANTA FE DRIVE, SUITE 300
- **CITY:** SOLANA BEACH
- **STATE:** CA
- **ZIP:** 92075

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Graphite Bio, Inc.
- **DATE OF NAME CHANGE:** 20210312

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Integral Medicines, Inc.
- **DATE OF NAME CHANGE:** 20200622
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Squarepoint Ops LLC
- **CENTRAL INDEX KEY:** 0001642575

**ORGANIZATION NAME:**
- **EIN:** 465665364
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G

**BUSINESS ADDRESS:**
- **STREET 1:** 250 W. 55TH STREET
- **STREET 2:** 32ND FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019
- **BUSINESS PHONE:** 011442036957214

**MAIL ADDRESS:**
- **STREET 1:** 250 W. 55TH STREET
- **STREET 2:** 32ND FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10019

## Ex-1

------

**JOINT FILING AGREEMENT**

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is, and that all subsequent amendments to this statement on Schedule 13G (including amendments on Schedule 13D) signed by each of the undersigned shall be, filed on behalf of each of them pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended. The undersigned acknowledge that each shall be responsible for the timely filing of this Schedule 13G and any amendments thereto, and for the completeness and accuracy of the information concerning them or it contained herein and therein, but shall not be responsible for the completeness and accuracy of the information concerning the others, except to the extent that they or it knows or has reason to believe that such information is inaccurate.

---

| |
|:---|
| Squarepoint Ops LLC |
| Signature: /s/ John Weitzer |
| Name/Title: John Weitzer, Chief Compliance Officer |
| Date: 4/8/2026 |

---

---

| |
|:---|
| Squarepoint Capital LLP |
| Signature: /s/ John Weitzer |
| Name/Title: John Weitzer, Chief Compliance Officer |
| Date: 4/8/2026 |

---

---

| |
|:---|
| Squarepoint Operations Private Limited |
| Signature: /s/ John Weitzer |
| Name/Title: John Weitzer, Chief Compliance Officer |
| Date: 4/8/2026 |

---

---

| |
|:---|
| Squarepoint (DIFC) Limited |
| Signature: /s/ John Weitzer |
| Name/Title: John Weitzer, Chief Compliance Officer |
| Date: 4/8/2026 |

---

---

| |
|:---|
| Squarepoint Master Fund Limited |
| Signature: /s/ John Weitzer |
| Name/Title: John Weitzer, Chief Compliance Officer |
| Date: 4/8/2026 |

---

---

| |
|:---|
| Squarepoint Core Master Fund Limited |
| Signature: /s/ John Weitzer |
| Name/Title: John Weitzer, Chief Compliance Officer |
| Date: 4/8/2026 |

---

------

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## SCHEDULE 13G

### Under the Securities Exchange Act of 1934

**Issuer:** LENZ Therapeutics, Inc.

**Title of Class of Securities:** Common Stock

**CUSIP Number:** —

**Date of Event Which Requires Filing of this Statement:** 04/01/2026

**Check the appropriate box to designate the rule pursuant to which this Schedule is filed:**

- [ ] Rule 13d-1(b)

- [x] Rule 13d-1(c)

- [ ] Rule 13d-1(d)

---

| 1. | Names of Reporting Persons<br>Squarepoint Ops LLC | Names of Reporting Persons<br>Squarepoint Ops LLC |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>1593246.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>1593246.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.1% | Percent of Class Represented by Amount in Row (9)<br>5.1% |
| 12. | Type of Reporting Person (See Instructions)<br>IA | Type of Reporting Person (See Instructions)<br>IA |

---

| 1. | Names of Reporting Persons<br>Squarepoint Capital LLP | Names of Reporting Persons<br>Squarepoint Capital LLP |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>X0 | Citizenship or Place of Organization<br>X0 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>1593246.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>1593246.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.1% | Percent of Class Represented by Amount in Row (9)<br>5.1% |
| 12. | Type of Reporting Person (See Instructions)<br>IA | Type of Reporting Person (See Instructions)<br>IA |

---

| 1. | Names of Reporting Persons<br>Squarepoint Operations Private Limited | Names of Reporting Persons<br>Squarepoint Operations Private Limited |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>U0 | Citizenship or Place of Organization<br>U0 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>1593246.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>1593246.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.1% | Percent of Class Represented by Amount in Row (9)<br>5.1% |
| 12. | Type of Reporting Person (See Instructions)<br>IA | Type of Reporting Person (See Instructions)<br>IA |

---

| 1. | Names of Reporting Persons<br>Squarepoint (DIFC) Ltd | Names of Reporting Persons<br>Squarepoint (DIFC) Ltd |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>C0 | Citizenship or Place of Organization<br>C0 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>1593246.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>1593246.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1593246.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.1% | Percent of Class Represented by Amount in Row (9)<br>5.1% |
| 12. | Type of Reporting Person (See Instructions)<br>IA | Type of Reporting Person (See Instructions)<br>IA |

---

| 1. | Names of Reporting Persons<br>Squarepoint Master Fund Limited | Names of Reporting Persons<br>Squarepoint Master Fund Limited |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>E9 | Citizenship or Place of Organization<br>E9 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>1590333.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>1590333.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1590333.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1590333.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>5.1% | Percent of Class Represented by Amount in Row (9)<br>5.1% |
| 12. | Type of Reporting Person (See Instructions)<br>OO | Type of Reporting Person (See Instructions)<br>OO |

---

| 1. | Names of Reporting Persons<br>Squarepoint Core Master Fund Limited | Names of Reporting Persons<br>Squarepoint Core Master Fund Limited |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [ ] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>E9 | Citizenship or Place of Organization<br>E9 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>2913.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>2913.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2913.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>2913.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>0.0% | Percent of Class Represented by Amount in Row (9)<br>0.0% |
| 12. | Type of Reporting Person (See Instructions)<br>OO | Type of Reporting Person (See Instructions)<br>OO |

---

**Item 1(a). Name of Issuer:**
LENZ Therapeutics, Inc.

**Item 1(b). Address of Issuer's Principal Executive Offices:**
201 LOMAS SANTA FE DRIVE, SUITE 300, SOLANA BEACH, CALIFORNIA, 92075.

**Item 2(a). Name of Person Filing:**
Squarepoint Ops LLC
Squarepoint Capital LLP
Squarepoint Operations Private Limited
Squarepoint (DIFC) Limited
Squarepoint Master Fund Limited
Squarepoint Core Master Fund Limited

**Item 2(b). Address of Principal Business Office:**
Squarepoint Ops LLC
Squarepoint Master Fund Limited
Squarepoint Core Master Fund Limited
250 W 55th Street 32nd Floor, New York, NY 10019 USA

Squarepoint Capital LLP
Citypoint, One Ropemaker Street, London, EC2Y 9AW UK

Squarepoint Operations Private Limited
88 Market Street, CapitaSpring, Level 49, 048948 Singapore

Squarepoint (DIFC) Limited
Unit L29-07, Level 29, ICD Brookfield Place, Dubai International Financial Centre, Dubai,
United Arab Emirates

**Item 2(c). Citizenship:**
Squarepoint Ops LLC- USA
Squarepoint Capital LLP- United Kingdom
Squarepoint Operations Private Limited- Singapore
Squarepoint (DIFC) Limited- United Arab Emirates
Squarepoint Master Fund Limited- Cayman Islands
Squarepoint Core Master Fund Limited- Cayman Islands

**Item 2(d). Title of Class of Securities:**
Common Stock

**Item 2(e). CUSIP Number:**
—

**Item 3. If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:**

(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d) [ ] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).

(e) [ ] An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);

(f) [ ] An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);

(g) [ ] A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j) [ ] A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), if filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:

(k) [ ] Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).

**Item 4. Ownership:**

**(a) Amount beneficially owned:**

Squarepoint Ops LLC- 1,593,246
Squarepoint Capital LLP- 1,593,246
Squarepoint Operations Private Limited- 1,593,246
Squarepoint (DIFC) Limited- 1,593,246
Squarepoint Master Fund Limited- 1,590,333
Squarepoint Core Master Fund Limited- 2,913

**(b) Percent of class:**

Squarepoint Ops LLC- 5.08%
Squarepoint Capital LLP- 5.08%
Squarepoint Operations Private Limited- 5.08%
Squarepoint (DIFC) Limited- 5.08%
Squarepoint Master Fund Limited- 5.07%
Squarepoint Core Master Fund Limited- 0.01%

**(c) Number of shares as to which the person has:**

**(i) Sole power to vote or to direct the vote:**

0

**(ii) Shared power to vote or to direct the vote:**

Squarepoint Ops LLC- 1,593,246
Squarepoint Capital LLP- 1,593,246
Squarepoint Operations Private Limited- 1,593,246
Squarepoint (DIFC) Limited- 1,593,246
Squarepoint Master Fund Limited- 1,590,333
Squarepoint Core Master Fund Limited- 2,913

**(iii) Sole power to dispose or to direct the disposition of:**

0

**(iv) Shared power to dispose or to direct the disposition of:**

Squarepoint Ops LLC- 1,593,246
Squarepoint Capital LLP- 1,593,246
Squarepoint Operations Private Limited- 1,593,246
Squarepoint (DIFC) Limited- 1,593,246
Squarepoint Master Fund Limited- 1,590,333
Squarepoint Core Master Fund Limited- 2,913

**Item 5. Ownership of Five Percent or Less of a Class.**

[x] If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following.

**Item 6. Ownership of More than 5 Percent on Behalf of Another Person.**

Not Applicable

**Item 7. Identification and Classification of the Subsidiary**

Not Applicable

**Item 8. Identification and Classification of Members of the Group**

Not Applicable

**Item 9. Notice of Dissolution of Group**

Not Applicable

**Item 10. Certification:**

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

### SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Squarepoint Ops LLC**

**Date:** 04/08/2026

**By:** /s/ John Weitzer

**Name & Title:** Chief Compliance Officer

**Squarepoint Capital LLP**

**Date:** 04/08/2026

**By:** /s/ John Weitzer

**Name & Title:** Chief Compliance Officer

**Squarepoint Operations Private Limited**

**Date:** 04/08/2026

**By:** /s/ John Weitzer

**Name & Title:** Chief Compliance Officer

**Squarepoint (DIFC) Ltd**

**Date:** 04/08/2026

**By:** /s/ John Weitzer

**Name & Title:** Chief Compliance Officer

**Squarepoint Master Fund Limited**

**Date:** 04/08/2026

**By:** /s/ John Weitzer

**Name & Title:** Chief Compliance Officer

**Squarepoint Core Master Fund Limited**

**Date:** 04/08/2026

**By:** /s/ John Weitzer

**Name & Title:** Chief Compliance Officer