# EDGAR Filing Document

**Accession Number:** 0000744218
**File Stem:** 0001104659-26-050884
**Filing Date:** 2026-4
**Character Count:** 265600
**Document Hash:** 0730d7ae16019cac25cdc390bb876dbd
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-26-050884.hdr.sgml**: 20260429

**ACCESSION NUMBER**: 0001104659-26-050884

**CONFORMED SUBMISSION TYPE**: DEF 14A

**PUBLIC DOCUMENT COUNT**: 69

**CONFORMED PERIOD OF REPORT**: 20260625

**FILED AS OF DATE**: 20260429

**DATE AS OF CHANGE**: 20260429

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Celldex Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0000744218
- **STANDARD INDUSTRIAL CLASSIFICATION:** IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 133191702
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DEF 14A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-15006
- **FILM NUMBER:** 26910609

**BUSINESS ADDRESS:**
- **STREET 1:** 53 FRONTAGE ROAD
- **STREET 2:** SUITE 220
- **CITY:** HAMPTON
- **STATE:** NJ
- **ZIP:** 08827
- **BUSINESS PHONE:** 908-200-7500

**MAIL ADDRESS:**
- **STREET 1:** 53 FRONTAGE ROAD
- **STREET 2:** SUITE 220
- **CITY:** HAMPTON
- **STATE:** NJ
- **ZIP:** 08827

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AVANT IMMUNOTHERAPEUTICS INC
- **DATE OF NAME CHANGE:** 19980828

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** T CELL SCIENCES INC
- **DATE OF NAME CHANGE:** 19920703

?xml version='1.0' encoding='ASCII'? tm261321-3_nonfiling - none - 21.5551736s

[**TABLE OF CONTENTS**](#TOC)

#### UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

### SCHEDULE 14A

#### Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.)
Filed by the Registrant ☒

Filed by a Party other than the Registrant ☐

Check the appropriate box:

☐

Preliminary Proxy Statement

☐

**Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))** 

☒

Definitive Proxy Statement

☐

Definitive Additional Materials

☐

Soliciting Material under §240.14a-12

### Celldex Therapeutics, Inc.
(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check all boxes that apply):

☒

No fee required.

☐

Fee paid previously with preliminary materials.

☐

Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11.

------

[**TABLE OF CONTENTS**](#TOC)

### Notice of Annual Meeting of Stockholders

---

| | | |
|:---|:---|:---|
| ![[MISSING IMAGE: ic_date-pn.jpg]](ic_date-pn.jpg)  | ![[MISSING IMAGE: ic_virtual-pn.jpg]](ic_virtual-pn.jpg)  | ![[MISSING IMAGE: ic_record-pn.jpg]](ic_record-pn.jpg)  |
| **Date and Time**  | **Virtual Meeting**  | **Record Date**  |
| **June 25, 2026** <br> at <br> **9:00 a.m.** <br> Eastern Time  | This year's meeting will be held online at: <u>virtualshareholdermeeting.com/CLDX2026</u>  | Only stockholders of record at the close of business on April 27, 2026 are entitled to receive notice of and to vote at the Annual Meeting or any postponement or adjournment thereof.  |

---

---

| | | | | |
|:---|:---|:---|:---|:---|
| **Proposals**  | **Items of Business**  | **Board Voting <br> Recommendation**  | **Board Voting <br> Recommendation**  | **Page <br> Reference**  |
| ![[MISSING IMAGE: ic_one-pn.jpg]](ic_one-pn.jpg)  | Elect nine directors to serve until the next Annual Meeting of Stockholders and until their respective successors shall have been duly elected and qualified;  | **FOR**  | ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | **[7](#tP1TE)**  |
| ![[MISSING IMAGE: ic_two-pn.jpg]](ic_two-pn.jpg)  | Ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the year ending December 31, 2026;  | **FOR**  | ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | **[53](#tP2RT)**  |
| ![[MISSING IMAGE: ic_three-pn.jpg]](ic_three-pn.jpg)  | Approve an amendment to our 2021 Omnibus Equity Incentive Plan, including an increase in the number of the shares reserved for issuance thereunder by 3,400,000 shares to 12,900,000 shares and a clarification regarding the tax withholding provisions applicable to awards under the 2021 Incentive Plan;  | **FOR**  | ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | **[55](#tP3AO)**  |
| ![[MISSING IMAGE: ic_four-pn.jpg]](ic_four-pn.jpg)  | Approve, on an advisory basis, the compensation of the Company's Named Executive Officers as disclosed in this proxy statement; and  | **FOR**  | ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | **[62](#tP4AV)**  |
|  | Address any other matters that may properly come before the meeting. |  |  |  |

---

#### YOUR VOTE IS IMPORTANT
Regardless of whether you plan to attend the live virtual meeting, we encourage you to vote as soon as possible in one of the following ways:

---

| | | | |
|:---|:---|:---|:---|
| ![[MISSING IMAGE: ic_mail-pn.jpg]](ic_mail-pn.jpg)  | ![[MISSING IMAGE: ic_telephone-pn.jpg]](ic_telephone-pn.jpg)  | ![[MISSING IMAGE: ic_internet-pn.jpg]](ic_internet-pn.jpg)  | ![[MISSING IMAGE: ic_virtual2-pn.jpg]](ic_virtual2-pn.jpg)  |
| **BY MAIL**  | **BY TELEPHONE**  | **VIA INTERNET**  | **AT THE VIRTUAL MEETING**  |
| Sign, date, and return your proxy card in the enclosed envelope  | submit your proxy <br> by telephone  | submit your proxy by <br> via the Internet  | Attend the Annual Meeting online at <br> <u>virtualshareholdermeeting.com/CLDX2026</u>  |

---

By Order of the Board of Directors <br> May 4, 2026 Hampton, NJ Sam Martin Chief Financial Officer and Secretary

------

[**TABLE OF CONTENTS**](#TOC)

**Table of Contents**

---

| | |
|:---|:---|
| **[About Us](#tABUS)**  | **[2](#tABUS)** |
| **[About the Meeting](#tATM)**  | **[3](#tATM)** |
| **[Proposal 1: Election of Directors](#tP1TE)**  | **[7](#tP1TE)** |
| &nbsp;&nbsp; [Nominees for Election](#tNFE)  | [7](#tNFE) |
| &nbsp;&nbsp; [Director Nominees](#tDINO)  | [8](#tDINO) |
| **[Information Regarding the Board of Directors and Corporate Governance](#tIRTB)**  | **[13](#tIRTB)**  |
| &nbsp;&nbsp; [Independence of the Board of Directors](#tIOTB)  | [13](#tIOTB) |
| &nbsp;&nbsp; [Board Leadership Structure](#tBLS)  | [13](#tBLS) |
| &nbsp;&nbsp; [Role of the Board in Risk Oversight](#tROTB)  | [14](#tROTB) |
| &nbsp;&nbsp; [Audit Committee](#tAUCO)  | [15](#tAUCO) |
| &nbsp;&nbsp; [Compensation and Organization Development Committee](#tCAOD)  | [15](#tCAOD) |
| &nbsp;&nbsp; [Nominating and Corporate Governance Committee](#tNACG)  | [16](#tNACG) |
| &nbsp;&nbsp; [Science and Regulatory Committee](#tSACC)  | [16](#tSACC) |
| &nbsp;&nbsp; [Director Selection Criteria](#tDSC)  | [16](#tDSC) |
| &nbsp;&nbsp; [Stockholder Nominations for Directorships](#tSNFD)  | [17](#tSNFD) |
| &nbsp;&nbsp; [Stockholder Communications](#tSTCO)  | [18](#tSTCO) |
| &nbsp;&nbsp; [Code of Business Conduct and Ethics](#tCOBC)  | [18](#tCOBC) |
| &nbsp;&nbsp; [Corporate Governance Matters](#tCGM)  | [18](#tCGM) |
| &nbsp;&nbsp; [Compliance Program](#tCOPR)  | [19](#tCOPR) |
| &nbsp;&nbsp; [Stock Ownership Guidelines](#tSOG)  | [19](#tSOG) |
| &nbsp;&nbsp; [Insider Trading Policy (including Anti-Hedging and <br> Anti-Pledging)](#tITPI)  | [19](#tITPI) |
| **[Sustainability & Corporate Responsibility](#tSCR)**  | **[20](#tSCR)** |
| **[Executive Officers](#tEXOF)**  | **[25](#tEXOF)** |
| **[Executive Compensation](#tEXCO)**  | **[26](#tEXCO)** |
| &nbsp;&nbsp; [Compensation Discussion and Analysis](#tCDAA)  | [26](#tCDAA) |
| &nbsp;&nbsp; [Compensation And Organization Development Committee Report](#tCAOD1)  | [37](#tCAOD1) |
| &nbsp;&nbsp; [Summary Compensation Table](#tSCT)  | [38](#tSCT) |
| &nbsp;&nbsp; [Grants of Plan-Based Awards](#tGOPA)  | [39](#tGOPA) |
| &nbsp;&nbsp; [Outstanding Equity Awards at Fiscal Year-End](#tOEAA)  | [39](#tOEAA) |
| &nbsp;&nbsp; [Option Exercises and Stock Vested](#tOEAS)  | [41](#tOEAS) |
| &nbsp;&nbsp; [Pension Benefits](#tPEBE)  | [41](#tPEBE) |
| &nbsp;&nbsp; [Nonqualified Deferred Compensation](#tNDC)  | [42](#tNDC) |
| &nbsp;&nbsp; [Potential Payments Upon Termination of Employment or Change in Control](#tPPUT)  | [42](#tPPUT) |
| &nbsp;&nbsp; [Securities Authorized For Issuance Under Equity Compensation Plans](#tSAFI)  | [43](#tSAFI) |
| &nbsp;&nbsp; [CEO Pay Ratio](#tCPR)  | [43](#tCPR) |

---

---

| | |
|:---|:---|
| &nbsp;&nbsp; [Pay Versus Performance Table](#tPVPT)  | [44](#tPVPT) |
| &nbsp;&nbsp; [Director Compensation](#tDICO)  | [47](#tDICO) |
| &nbsp;&nbsp; [Compensation and Organization Development Committee Interlocks and Insider Participation](#tCAOD2)  | [48](#tCAOD2) |
| &nbsp;&nbsp; [Risk Considerations](#tRICO)  | [48](#tRICO) |
| &nbsp;&nbsp; [Stock Ownership Policy — Non-Employee Directors](#tSOPN)  | [48](#tSOPN) |
| &nbsp;&nbsp; [Report of The Audit Committee](#tROTA)  | [49](#tROTA) |
| &nbsp;&nbsp; [Security Ownership of Certain Beneficial Owners and Management](#tSOOC)  | [50](#tSOOC) |
| &nbsp;&nbsp; [Transactions with Related Persons](#tTWRP)  | [52](#tTWRP) |
| **[Proposal 2: Ratification of Independent Public Accounting Firm](#tP2RT)**  | **[53](#tP2RT)**  |
| &nbsp;&nbsp; [Principal Accountant Fees and Services](#tPAFA)  | [53](#tPAFA) |
| &nbsp;&nbsp; [Audit Fees](#tAUFE)  | [53](#tAUFE) |
| &nbsp;&nbsp; [All Other Fees](#tAOF)  | [53](#tAOF) |
| **[Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan](#tP3AO)**  | **[55](#tP3AO)**  |
| &nbsp;&nbsp; [General](#tGEN)  | [55](#tGEN) |
| &nbsp;&nbsp; [Description of the 2021 Incentive Plan](#tDOT2)  | [56](#tDOT2) |
| &nbsp;&nbsp; [Other Information](#tOTIN)  | [58](#tOTIN) |
| &nbsp;&nbsp; [Material Federal Income Tax Consequences](#tMFIT)  | [58](#tMFIT) |
| &nbsp;&nbsp; [Treatment of Options](#tTOO)  | [58](#tTOO) |
| &nbsp;&nbsp; [Treatment of Stock Appreciation Rights](#tTOSA)  | [59](#tTOSA) |
| &nbsp;&nbsp; [Treatment of Stock Awards](#tTOSA1)  | [59](#tTOSA1) |
| &nbsp;&nbsp; [Section 409A](#tSE40)  | [60](#tSE40) |
| &nbsp;&nbsp; [Potential Limitation on Company Deductions](#tPLOC)  | [60](#tPLOC) |
| &nbsp;&nbsp; [Restrictions on Resale](#tROR)  | [60](#tROR) |
| &nbsp;&nbsp; [Tax Withholding](#tTAWI)  | [60](#tTAWI) |
| &nbsp;&nbsp; [New Plan Benefits](#tNPB)  | [60](#tNPB) |
| &nbsp;&nbsp; [Options outstanding under the 2021 Incentive Plan as of March 31, 2026](#tOGUT)  | [60](#tOGUT) |
| **[Proposal 4: Advisory Vote on Executive Compensation](#tP4AV)**  | **[62](#tP4AV)**  |
| **[Stockholder Proposals](#tSTPR)**  | **[63](#tSTPR)** |
| &nbsp;&nbsp; [Submitting Proxy Proposals and Director Nominations for the 2027 Annual Meeting](#tSPPA)  | [63](#tSPPA) |
| **[Where You Can Find Additional Information](#tWYCF)**  | **[64](#tWYCF)**  |
| **[Other Matters](#tOTMA)**  | **[65](#tOTMA)** |
| **[Annex A](#tANA)**  | **[66](#tANA)**  |

---

------

[**TABLE OF CONTENTS**](#TOC)

About Us

### About Us
Celldex is a clinical stage biotechnology company pioneering new horizons in immunology to deliver life-changing therapies.

 **Our Pipeline**

<br> Our pipeline includes antibody-based therapeutics which have the ability to engage the human immune system and/or directly affect critical pathways to improve the lives of patients with severe allergic, inflammatory and autoimmune disorders.

![[MISSING IMAGE: tb_pipeline-4c.jpg]](tb_pipeline-4c.jpg)

\*

ColdU and SD are subtypes under the global Phase 3 CIndU (Chronic Inducible Urticaria) program

---

| | |
|:---|:---|
| **Barzolvolimab**  | **CDX-622**  |
| Barzolvolimab is a humanized monoclonal antibody with a novel mechanism of action that targets mast cells by binding with high specificity to a unique part of the KIT receptor and potently inhibiting its activity. The KIT receptor is abundantly expressed by mast cells and critical for their function and survival. Mast cells are drivers of inflammatory responses such as hypersensitivity and allergic reactions and, in certain inflammatory diseases, such as chronic urticarias, mast cell activation plays a central role in the onset and progression of the disease. Based on data from robust, randomized, placebo controlled Phase 2 studies, barzolvolimab has significant potential as a first-in-class and best-in-disease treatment option for patients with chronic spontaneous urticaria (CSU), cold urticaria (ColdU) and symptomatic dermographism (SD). Barzolvolimab is currently being studied in Phase 3 studies in CSU and ColdU/SD and Phase 2 studies in prurigo nodularis (PN) and atopic dermatitis (AD), with additional indications planned for the future.  | CDX-622 is a bispecific antibody that targets two complementary, clinically validated pathways that drive chronic inflammation, potently neutralizing the alarmin thymic stromal lymphopoietin (TSLP) and depleting mast cells via stem cell factor (SCF) starvation. SCF activation of the KIT receptor is required for mast cell survival and plays a key role in their activation, maturation and tissue recruitment. Combined neutralization of SCF and TSLP with CDX-622 is expected to simultaneously reduce tissue mast cells and inhibit Type 2 inflammatory responses to potentially offer enhanced therapeutic benefit in inflammatory and fibrotic disorders. CDX-622 is currently being studied in a Phase 1 proof of mechanism study in adults with mild to moderate asthma.  |

---

Celldex Therapeutics \| 1

------

**[**TABLE OF CONTENTS**](#TOC)

About Us

Our Science

Driven by our deep and longstanding experience developing antibody-based immunotherapies, Celldex's proprietary antibody programs and technologies are supported by robust in-house capabilities, enabling the optimized discovery and development of innovative scientific programs.

---

| | | | | |
|:---|:---|:---|:---|:---|
| ![[MISSING IMAGE: ic_scientific-pn.jpg]](ic_scientific-pn.jpg)  | ![[MISSING IMAGE: ic_edgescience-pn.jpg]](ic_edgescience-pn.jpg)  | ![[MISSING IMAGE: ic_innovation-pn.jpg]](ic_innovation-pn.jpg)  | ![[MISSING IMAGE: ic_bispecific-pn.jpg]](ic_bispecific-pn.jpg)  | ![[MISSING IMAGE: ic_gearhouse-pn.jpg]](ic_gearhouse-pn.jpg)  |
| Deep and longstanding experience developing antibody-based immunotherapies  | Cutting edge science with patient- focused approach  | Proprietary antibody programs using validated technologies drive innovation  | Next generation bispecific antibody platform  | Robust in-house capabilities enable optimized development process  |

---

2 \| Celldex Therapeutics

------**

[**TABLE OF CONTENTS**](#TOC)

Proxy Statement

### Proxy Statement
This proxy statement contains information related to the Annual Meeting of Stockholders to be held on June 25, 2026 at 9:00 a.m. Eastern Time. We are holding the Annual Meeting virtually via the Internet. In order to attend our Annual Meeting, you must log in to www.virtualshareholdermeeting.com/CLDX2026 using the 16-digit control number on the notice, proxy card or voting instruction form that accompanied the proxy materials.

Our Annual Meeting could be adjourned or postponed to another date and/or time. A list of record holders of the Company's common stock entitled to vote at the Annual Meeting will be available for examination by any stockholder, for any purpose germane to the Annual Meeting, at our principal offices at Perryville III Building, 53 Frontage Road, Suite 220, Hampton, New Jersey 08827, during normal business hours for ten days prior to the Annual Meeting.

The enclosed proxy is solicited by the Board of Directors of Celldex Therapeutics, Inc. (the "Board"). The proxy materials relating to the Annual Meeting are being mailed to stockholders entitled to vote at the meeting on or about May 4, 2026.

#### Important Notice of Availability of Proxy Materials for the Annual Meeting of Stockholders to be held on June 25, 2026.
**Our proxy materials, including our Proxy Statement for the 2026 Annual Meeting, 2025 Annual Report to Stockholders (which contains our Annual Report on Form 10-K) and proxy card, are available on the Internet at www.proxyvote.com.** 

#### About the Meeting

#### Why are we calling this Annual Meeting?
We are calling the Annual Meeting to seek the approval of our stockholders to:

• elect nine directors to serve until the next Annual Meeting of Stockholders and until their respective successors shall have been duly elected and qualified;

• ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the year ending December 31, 2026;

• approve an amendment to our 2021 Omnibus Equity Incentive Plan (the "2021 Incentive Plan"), including an increase in the number of the shares reserved for issuance thereunder by 3,400,000 shares to 12,900,000 shares and a clarification regarding the tax withholding provisions applicable to awards under the 2021 Incentive Plan

• approve, on an advisory basis, the compensation of the Company's Named Executive Officers as disclosed in this proxy statement; and

• address any other matters that may properly come before the meeting.

#### What are the Board's recommendations?
Our Board of Directors recommends that you vote:

• ***FOR*** the election of each of the nine director nominees;

• ***FOR*** the ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the year ending December 31, 2026;

• ***FOR*** the approval of an amendment to our 2021 Incentive Plan, including an increase in the number of the shares reserved for issuance thereunder by 3,400,000 shares to 12,900,000 shares and a clarification regarding the tax withholding provisions applicable to awards under the 2021 Incentive Plan and

• ***FOR*** the advisory vote to approve the compensation of our Named Executive Officers as described in this proxy statement.

#### Who is entitled to vote at the meeting?
Only stockholders of record at the close of business on the record date, April 27, 2026, are entitled to receive notice of the Annual Meeting and to vote the shares of common stock that they held on that date at the meeting, or any postponement or adjournment of the meeting. Holders of our common stock are entitled to one vote per share on each matter to be voted upon. As of the record date, we had 78,492,072 outstanding shares of common stock.

Celldex Therapeutics \| 3

------

[**TABLE OF CONTENTS**](#TOC)

Proxy Statement

#### Who can attend the meeting?
All stockholders as of the record date, or their duly appointed proxies, may attend the Annual Meeting. Attendance shall solely be via the Internet at www.virtualshareholdermeeting.com/CLDX2026 using the 16-digit control number on the notice, proxy card or voting instruction form that accompanied the proxy materials.

The live webcast of the Annual Meeting will begin promptly at 9:00 am Eastern Time. Online access to the audio webcast will open approximately 10 minutes prior to the start of the Annual Meeting to allow time for our stockholders to log in and test their devices' audio system. We encourage our stockholders to access the meeting in advance of the designated start time.

Stockholders may also vote, and submit written questions, during the Annual Meeting on www.virtualshareholdermeeting.com/CLDX2026. To demonstrate proof of stock ownership, you will need to enter the 16-digit control number received with your notice, proxy card or voting instruction form to submit questions and vote at our Annual Meeting. If you hold your shares in "street name" (that is, through a broker or other nominee), you will need authorization from your broker or nominee in order to vote. We intend to answer questions submitted during the meeting that are pertinent to the Company and the items being brought for stockholder vote at the Annual Meeting, as time permits, and in accordance with the Rules of Conduct for the Annual Meeting. To promote fairness, efficiently use the Company's resources and ensure all stockholder questions are able to be addressed, we will respond to no more than one question from a single stockholder. Questions and answers will be grouped by topic and substantially similar questions will be grouped and answered once. We have retained Broadridge Financial Solutions to host our virtual annual meeting and to distribute, receive, count and tabulate proxies.

#### What constitutes a quorum?
The presence at the Annual Meeting, in person or by proxy, of the holders of a majority of our common stock outstanding on the record date will constitute a quorum for our meeting. Signed proxies received but not voted and broker non-votes will be included in the calculation of the number of shares considered to be present at the meeting.

#### How do I vote?
You can vote on matters that come before the Annual Meeting by completing, dating and signing the enclosed proxy card and returning it in the enclosed postage-paid envelope.

Your shares will be voted as you indicate on your proxy card. If you vote the enclosed proxy but you do not indicate your voting preferences, and with respect to any other matter that properly comes before the meeting, the individuals named on the proxy card will vote your shares FOR the matters submitted at the meeting, or if no recommendation is given, in their own discretion.

If you are a stockholder of record, to submit your proxy by telephone or via the Internet, follow the instructions on the proxy card. If you hold your shares in street name, you may vote by telephone or via the Internet as instructed by your broker, bank or other nominee.

You will have the right to vote at the Annual Meeting. You will have the right to vote on the day of, or during, the Annual Meeting on www.virtualshareholdermeeting.com/CLDX2026. To demonstrate proof of stock ownership, you will need to enter the 16-digit control number received with your notice, proxy card or voting instruction form to vote at our Annual Meeting.

If you attend the Annual Meeting and prefer to vote in person, you may do so even if you have already voted your shares by proxy. Even if you plan to attend our Annual Meeting, we recommend that you also submit your proxy as described above so that your vote will be counted if you later decide not to attend our Annual Meeting.

#### What if I vote and then change my mind?
You may revoke your proxy at any time before it is exercised by:

• filing with the Secretary of the Company a notice of revocation;

• sending in another duly executed proxy bearing a later date; or

• attending the meeting and casting your vote in person.

Your latest vote will be the vote that is counted.

4 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proxy Statement

#### What is the difference between holding shares as a stockholder of record and as a beneficial owner?
Many of our stockholders hold their shares through a stockbroker, bank or other nominee rather than directly in their own name. As summarized below, there are some distinctions between shares held of record and those owned beneficially.

*Stockholder of Record* 

If your shares are registered directly in your name with our transfer agent, Computershare Trust Company, N.A., you are considered, with respect to those shares, the stockholder of record. As the stockholder of record, you have the right to directly grant your voting proxy or to vote in person at the Annual Meeting.

*Beneficial Owner* 

If your shares are held in a stock brokerage account or by a bank or other nominee, you are considered the beneficial owner of shares held in street name, and these proxy materials are being forwarded to you by your broker, bank or nominee which is considered, with respect to those shares, the stockholder of record. As the beneficial owner, you have the right to direct your broker as to how to vote and are also invited to attend the Annual Meeting. However, because you are not the stockholder of record, you may not vote these shares in person at the Annual Meeting unless you obtain a signed proxy from the record holder giving you the right to vote the shares. If you do not provide the stockholder of record with voting instructions or otherwise obtain a signed proxy from the record holder giving you the right to vote the shares, broker non-votes may occur for the shares that you beneficially own. The effect of broker non-votes is more specifically described in "What vote is required to approve each proposal?" below.

#### What are "broker non-votes"?
Banks and brokers acting as nominees are permitted to use discretionary voting authority to vote for proposals that are deemed "routine" by the New York Stock Exchange, which means that they can submit a proxy or cast a ballot on behalf of stockholders who do not provides a specific voting instruction. Brokers, banks or other nominees are not permitted to use discretionary voting authority to vote for proposals that are deemed "non-routine" by the New York Stock Exchange. The determination of which proposals are deemed "routine" versus "non-routine" may not be made by the New York Stock Exchange until after the date on which this proxy statement has been mailed to you. As such, it is important that you provide voting instructions to your bank, broker or other nominee as to how to vote your shares, if you wish to ensure that your shares are present and voted at the Annual Meeting on all matters and if you wish to direct the voting of your shares on "routine" matters.

When there is at least one "routine" matter to be considered at a meeting, a broker "non-vote" occurs when a proposal is deemed "non-routine" and a nominee holding shares for a beneficial owner does not have discretionary voting authority with respect to the "non-routine" matter being considered and has not received instructions from the beneficial owner.

The election of directors (Proposal No. 1), the approval of an amendment to our 2021 Incentive Plan including an increase in the number of the shares reserved for issuance thereunder by 3,400,000 shares to 12,900,000 shares and a clarification regarding the tax withholding provisions applicable to awards under the 2021 Incentive Plan (Proposal No. 3) and the advisory vote on the compensation of our Named Executive Officers (Proposal No. 4) are generally considered to be "non-routine" matters, and brokers, banks or other nominees are not permitted to vote on those matters if the broker, bank or other nominee has not received instructions from the beneficial owner. Accordingly, it is particularly important that beneficial owners instruct their brokers, banks or other nominees how they wish to vote their shares on these proposals. The ratification of our independent registered public accounting firm (Proposal No. 2) is generally considered to be a "routine" matter, and hence, a broker, bank or other nominee may be able to vote on Proposal No. 2 even if it does not receive instructions from the beneficial owner.

#### What vote is required to approve each proposal?
Holders of a majority of the outstanding shares as of the record date entitled to vote at the meeting must be present, in person or by proxy, at the Annual Meeting in order to establish the required quorum for the transaction of business. Pursuant to Delaware corporate law, abstentions and broker non-votes will be counted for the purpose of determining whether a quorum is present.

Assuming that a quorum is present, the following votes will be required:

• With respect to the election of directors (Proposal No. 1), each nominee presented in Proposal 1 must be elected by a majority of the votes cast in person or by proxy at the Annual Meeting. Nominees are elected by a majority vote for non-contested director elections. Because the number of nominees properly nominated for the Annual Meeting is the same as the number of directors to be elected, the election of directors at this Annual Meeting is non-contested. If the

Celldex Therapeutics \| 5

------

[**TABLE OF CONTENTS**](#TOC)

Proxy Statement

number of votes "For" a nominee exceeds the number of votes "Against" such nominee (among votes properly cast in person or by proxy), then the nominee will be elected. Abstentions and broker non-votes will have no effect on Proposal 1.

• With respect to the ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm (Proposal No. 2), approval will require the affirmative vote of a majority of the votes cast, affirmatively or negatively, on Proposal No. 2 at the Annual Meeting. Accordingly, abstentions, if any, will not have any effect on the outcome of Proposal 2. Because Proposal 2 is considered a "routine" proposal, no broker non-votes will occur with respect to Proposal 2.

• With respect to the approval of an amendment to our 2021 Incentive Plan including an increase in the number of the shares reserved for issuance thereunder by 3,400,000 shares to 12,900,000 shares and a clarification regarding the tax withholding provisions applicable to awards under the 2021 Incentive Plan (Proposal No. 3) and the advisory vote on the compensation of our Named Executive Officers (Proposal No. 4), approval will require the affirmative vote of a majority of the votes cast, affirmatively or negatively, on such proposal. Accordingly, abstentions, if any, will not have any effect the outcomes of Proposals Nos. 3 and 4. Broker non-votes, if any, will have no effect on Proposals 3 and 4.

Holders of the common stock will not have any dissenters' rights of appraisal in connection with any of the matters to be voted on at the meeting.

#### How are we soliciting this proxy?
We are soliciting this proxy on behalf of our Board of Directors by mail and will pay all expenses associated therewith. Some of our officers and other employees also may, but without compensation other than their regular compensation, solicit proxies by further mailing or personal conversations, or by telephone, facsimile or other electronic means. We will also, upon request, reimburse brokers and other persons holding stock in their names, or in the names of nominees, for their reasonable out-of-pocket expenses for forwarding proxy materials to the beneficial owners of the capital stock and to obtain proxies.

6 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 1: Election of Directors

### Proposal 1: To Elect Nine Directors to Serve Until the Next Annual Meeting and Until Their Successors Have Been Duly Elected and Qualified (Proposal No. 1)
At the Annual Meeting, nine directors are to be elected. All directors of the Company hold office until the next Annual Meeting of Stockholders or until their respective successors are duly elected and qualified or their earlier resignation or removal.

It is the intention of the persons named in the proxies for the holders of common stock to vote the proxies for the election of the nominees named below, unless otherwise specified in any particular proxy. Our management does not contemplate that the nominees will become unavailable for any reason, but if that should occur before the meeting, proxies will be voted for another nominee, or other nominees, to be selected by our Board of Directors. In accordance with our by-laws and Delaware law, a stockholder entitled to vote for the election of directors may withhold authority to vote for certain nominees for directors or may withhold authority to vote for all nominees for directors. Director nominees are elected by a majority vote in non-contested elections of directors. Because the number of nominees properly nominated for the Annual Meeting is the same as the number of directors to be elected, the election of directors at this Annual Meeting is non-contested. Accordingly, each director nominee must be elected by a majority of the votes cast in person or by proxy at the Annual Meeting. Stockholders may not vote, or submit a proxy, for a greater number of nominees than the nine nominees named below.

#### Nominees for Election
The persons listed below are our current directors that have been nominated for re-election or nominees for election at the Annual Meeting (the "Director Nominees") to fill the nine director positions to be elected by the holders of the common stock.

---

| | |
|:---|:---|
| **Proposal 1: <br> Election of Directors**  | **Our Board recommends that you vote "FOR" the Board's Nominees.**  |

---

---

| | | |
|:---|:---|:---|
| **HARRY H. PENNER, JR.**  | **ANTHONY S. MARUCCI**  | **KEITH L. BROWNLIE**  |
| **Director**  | **Chief Executive Officer**  | **Director**  |
| Age: **80** <br> Director since **January 1997** <br> Public Boards: **1**  | Age: **64** <br> Director since **December 2008** <br> Public Boards: **1**  | Age: **73** <br> Director since **June 2017** <br> Public Boards: **1**  |
| **CHERYL L. COHEN**  | **HERBERT J. CONRAD**  | **RITA I. JAIN, M.D.**  |
| **Director**  | **Director**  | **Director**  |
| Age: **60** <br> Director since **June 2022** <br> Public Boards: **2**  | Age: **93** <br> Director since **March 2008** <br> Public Boards: **1**  | Age: **64** <br> Director since **February 2023** <br> Public Boards: **2**  |
| **JAMES J. MARINO**  | **GARRY A. NEIL, M.D.**  | **DENICE TORRES**  |
| **Director**  | **Director**  | **Director**  |
| Age: **76** <br> Director since **March 2017** <br> Public Boards: **1**  | Age: **72** <br> Director since **June 2022** <br> Public Boards: **2**  | Age: **66** <br> Director since **June 2025** <br> Public Boards: **2**  |

---

Celldex Therapeutics \| 7

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 1: Election of Directors

The following biographical descriptions set forth certain information with respect to the Director Nominees, based on information furnished to Celldex by each Director Nominee. Public company boards that nominees have served since 2021 are noted with\*.

#### Director Nominees

---

| | | |
|:---|:---|:---|
| **HARRY H. PENNER, JR., 80**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Chair** <br> since January 1997  | &nbsp;&nbsp;&nbsp; **AVANT**  | &nbsp;&nbsp; Board and Chairman from January 1997 prior to the consummation of our merger with AVANT  |
| **PUBLIC BOARDS: <br> 1**  | **Nascent BioScience, LLC**  | &nbsp;&nbsp; **Served as Chairman and Chief Executive Officer from 2001 to June 2023**  |
| **COMMITTEES: <br> None**  | Neurogen Corporation  | &nbsp;&nbsp; President, Chief Executive Officer and Vice Chairman from 1993 to 2001  |
| **EDUCATION:** <br> B.A. from the University of Virginia, a J.D. from Fordham University, and an L.L.M. in International Law from New York <br> University  | Novo Nordisk A/S  | &nbsp;&nbsp; Executive Vice President and General Counsel in Denmark from 1985 to 1988 <br> Executive Vice President for North America from 1988 to 1993  |
|  | BioCT  | &nbsp;&nbsp; Former Chair <br> Former BioScience Advisor to the Governor and the State of Connecticut  |
|  | Connecticut Technology Council  | &nbsp;&nbsp; Former Chair  |
|  | **Connecticut Board of Governors of Higher Education**  | &nbsp;&nbsp; **Former Chair**  |
|  | NeuroCyte Therapeutics, Inc.  | &nbsp;&nbsp; Currently Chair  |

---

---

| | | |
|:---|:---|:---|
| **ANTHONY S. MARUCCI, 64**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Founder, President and CEO** <br> Since September 2008 <br> (Director since December 2008)  | Celldex  | &nbsp;&nbsp; Former Vice President, Chief Financial Officer, Treasurer and Secretary  |
| **PUBLIC BOARDS: <br> 1**  | Medarex  | &nbsp;&nbsp; Treasurer (now a part of Bristol-Myers Squibb Co.) from December 1998 to March 2004 and senior financial positions from December 1998 to March 2003  |
| **COMMITTEES: <br> None**  | Genenta Science S.p.A.\*  | &nbsp;&nbsp; Board of directors from May 2021 to April 2024  |
| **EDUCATION:** <br> M.B.A. from Columbia University and <br> M.H.L. from Brown University  | BioNJ Inc.  | &nbsp;&nbsp; Board of Trustees  |

---

8 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 1: Election of Directors

---

| | | |
|:---|:---|:---|
| **KEITH L. BROWNLIE, 73**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since June 2017  | Ernst & Young LLP  | &nbsp;&nbsp; Former Audit partner for numerous public companies and was the Life Sciences Industry Leader for the New York Metro Area until 2009  |
| **PUBLIC BOARDS: <br> 1**  | Soligenix, Inc.  | &nbsp;&nbsp; Board of directors from 2010 until 2019  |
| **COMMITTEES: <br> Audit**  | &nbsp;&nbsp;&nbsp; **Phio Pharmaceuticals Corp.** <br> (formerly RXi Pharmaceuticals Corporation)  | &nbsp;&nbsp; Board of directors from 2012 until 2019  |
| **EDUCATION:** <br> B.S. in Accounting from Lehigh University <br> and is a Certified Public Accountant  | Cancer Genetics, Inc.  | &nbsp;&nbsp; Board of directors from 2013 to 2014  |
|  | EpiCept Corporation  | &nbsp;&nbsp; Board of directors from 2011 to 2013  |

---

---

| | | |
|:---|:---|:---|
| **CHERYL L. COHEN, 60**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since June 2022  | CLC Consulting  | &nbsp;&nbsp; President since 2008  |
| **PUBLIC BOARDS: <br> 2**  | Medivation, Inc.  | &nbsp;&nbsp; Chief Commercial Officer from August 2011 to July 2014, where she built the company's commercial organization and led her team to successfully launch the oncology drug, Xtandi<sup>®</sup>  |
| **COMMITTEES: <br> Compensation and Organization Development, Science and Commercialization**  | Johnson & Johnson  | &nbsp;&nbsp; Former Vice President of the Rheumatology Franchise  |
| **EDUCATION: <br> B.A. degree from Saint Joseph College**  | Solvay Pharmaceuticals  | &nbsp;&nbsp; Former management and sales  |
|  | &nbsp;&nbsp;&nbsp; **Immunity Bio\*** <br> (previously NantKwest)  | &nbsp;&nbsp; Board of directors since 2019  |
|  | MEI Pharma\*  | &nbsp;&nbsp; Board of directors from April 2020 to December 2022  |
|  | Ignyte Acquisition Corp.  | &nbsp;&nbsp; Board of directors from January 2021 to April 2022  |

---

---

| | | |
|:---|:---|:---|
| **HERBERT J. CONRAD, 93**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since March 2008  | Hoffmann-La Roche, Inc.  | &nbsp;&nbsp; President of the U.S. Pharmaceuticals Division from 1982 to 1993  |
| **PUBLIC BOARDS: <br> 1**  | Matinas BioPharma Holdings, Inc.\*  | &nbsp;&nbsp; Former director from 2012 to February 2025  |
| **COMMITTEES: <br> Nominating and Corporate Governance**  | **Seaver Autism Center at Mount Sinai Hospital**  | &nbsp;&nbsp; **Advisor**  |
| **EDUCATION:** <br> B.S. and M.S. degrees from the Brooklyn College of Pharmacy and an honorary Doctorate in Humane Letters from Long Island University  | Pharmasset, Inc., GenVec, Inc. and <br> Bone Care International, Inc.  | &nbsp;&nbsp; Former Chairman of the Board of Directors  |
| **EDUCATION:** <br> B.S. and M.S. degrees from the Brooklyn College of Pharmacy and an honorary Doctorate in Humane Letters from Long Island University  | Arbutus Biopharma Corporation  | &nbsp;&nbsp; Former director  |
| **EDUCATION:** <br> B.S. and M.S. degrees from the Brooklyn College of Pharmacy and an honorary Doctorate in Humane Letters from Long Island University  | Reliant Pharmaceuticals, Inc.  | &nbsp;&nbsp; Former director and co-founder  |

---

Celldex Therapeutics \| 9

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 1: Election of Directors

---

| | | |
|:---|:---|:---|
| **RITA I. JAIN, M.D., 64**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since February 2023  | AnaptysBio, Inc.\*  | &nbsp;&nbsp; Board of directors since April 2023  |
| **PUBLIC BOARDS: <br> 4**  | Avalo Therapeutics, Inc.\*  | &nbsp;&nbsp; Board of directors since June 2025  |
| **COMMITTEES: <br> Nominating and Corporate Governance, Science and Commercialization**  | **SAB Biotherapeutics, Inc.\***  | &nbsp;&nbsp; **Board of directors since January 2026**  |
| **EDUCATION:** <br> B.S. degree in biology from Long Island University, and her M.D. from the State University of New York at Stony Brook School of Medicine  | Provention Bio, Inc.  | &nbsp;&nbsp; Board of Directors from January 2023 until its acquisition by Sanofi in April 2023  |
|  | AM-Pharma B.V.  | &nbsp;&nbsp; Supervisory Board from 2020 until 2023  |
|  | ChemoCentryx, Inc.  | &nbsp;&nbsp; Board of Directors from 2019 until its acquisition by Amgen in 2022 <br> Executive Vice President and Chief Medical Officer from 2021 to 2022  |
|  | Immunovant, Inc.  | &nbsp;&nbsp; Chief Medical Officer in 2021  |
|  | Heartwood Biopharma Group  | &nbsp;&nbsp; Chief Executive Officer from August 2021 until December 2023  |
|  | Akebia Therapeutics, Inc.  | &nbsp;&nbsp; Senior Vice President and Chief Medical Officer from 2017 to 2019  |
|  | AbbVie Inc.  | &nbsp;&nbsp; Vice President in Clinical Development from 2013 to 2016, including Men's and Women's Health and Metabolic Development  |
|  | Abbott Laboratories  | &nbsp;&nbsp; Various leadership roles from 2003 through 2012, including as Divisional Vice President of Pain, Respiratory and Metabolic Disease Development  |

---

---

| | | |
|:---|:---|:---|
| **JAMES J. MARINO, 76**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since March 2017  | Dechert LLP  | &nbsp;&nbsp; Former Partner at the global law firm, where he served as Managing Partner of the Princeton Office and Chair of Life Science practice  |
| **PUBLIC BOARDS: <br> 1**  | &nbsp;&nbsp;&nbsp; **Traws Pharma, Inc.\*** <br> (formerly Onconova Therapeutics, Inc.)  | &nbsp;&nbsp; Former director from 2015 through September 2024 and Chairman of the Board  |
| **COMMITTEES: <br> Audit, Compensation and Organization Development**  | Pharmacopeia Inc.  | &nbsp;&nbsp; Former director  |
| **EDUCATION:** <br> B.A., M.B.A., and J.D. from Rutgers University  | BioNJ Inc.  | &nbsp;&nbsp; Co-founder and former counsel  |
|  | Wake Forest University  | &nbsp;&nbsp; Life Trustee  |

---

10 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 1: Election of Directors

---

| | | |
|:---|:---|:---|
| **GARRY NEIL, M.D., 72**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since June 2022  | Avalo Therapeutics\*  | &nbsp;&nbsp; Chief Executive Officer since February 2022 and Chairman of the Board from August 2022 to March 2025 <br> Senior Scientific Adviser and Chief Scientific Officer from February 2020 to February 2022 <br> Served as Chief Scientific Officer from September 2013 to February 2020  |
| **PUBLIC BOARDS: <br> 2**  | Apple Tree Partners  | &nbsp;&nbsp; Partner from September 2012 to September 2013  |
| **COMMITTEES: <br> Audit, Nominating and Corporate Governance**  | Johnson & Johnson  | &nbsp;&nbsp; Corporate Vice President of Science & Technology from November 2007 to August 2012  |
| **COMMITTEES: <br> Audit, Nominating and Corporate Governance**  | **Johnson & Johnson Pharmaceutical Research and Development**  | &nbsp;&nbsp; **Former Group President**  |
| **EDUCATION:** <br> B.S. from the University of Saskatchewan and an M.D. from the University of Saskatchewan College of Medicine. He completed postdoctoral clinical training in internal medicine and gastroenterology at the University of Toronto. Dr. Neil also completed a postdoctoral research fellowship at the Research Institute of Scripps Clinic  | Merck KGaA/EMD Pharmaceuticals  | &nbsp;&nbsp; Former Vice President of Research & Development  |
| **EDUCATION:** <br> B.S. from the University of Saskatchewan and an M.D. from the University of Saskatchewan College of Medicine. He completed postdoctoral clinical training in internal medicine and gastroenterology at the University of Toronto. Dr. Neil also completed a postdoctoral research fellowship at the Research Institute of Scripps Clinic  | AstraZeneca and Astra Merck  | &nbsp;&nbsp; Former Vice President of Clinical Research  |
| **EDUCATION:** <br> B.S. from the University of Saskatchewan and an M.D. from the University of Saskatchewan College of Medicine. He completed postdoctoral clinical training in internal medicine and gastroenterology at the University of Toronto. Dr. Neil also completed a postdoctoral research fellowship at the Research Institute of Scripps Clinic  | Arena Pharmaceuticals, Inc.  | &nbsp;&nbsp; Board of directors since February 2017 and as its Chair since February 2021  |
| **EDUCATION:** <br> B.S. from the University of Saskatchewan and an M.D. from the University of Saskatchewan College of Medicine. He completed postdoctoral clinical training in internal medicine and gastroenterology at the University of Toronto. Dr. Neil also completed a postdoctoral research fellowship at the Research Institute of Scripps Clinic  | Zura Bio Limited\*  | &nbsp;&nbsp; Board of directors from March 2023 to November 2023  |
| **EDUCATION:** <br> B.S. from the University of Saskatchewan and an M.D. from the University of Saskatchewan College of Medicine. He completed postdoctoral clinical training in internal medicine and gastroenterology at the University of Toronto. Dr. Neil also completed a postdoctoral research fellowship at the Research Institute of Scripps Clinic  | GTx, Inc.  | &nbsp;&nbsp; Board of directors from August 2016 to May 2019  |
|  | Hackensack Meridian Medical School in Hackensack, New Jersey  | &nbsp;&nbsp; Board of the Center for Discovery and Innovation  |
|  | TransCelerate Biopharma, Inc.  | &nbsp;&nbsp; Founding Chairman and past member of the board from 2012 to 2019  |
|  | &nbsp;&nbsp;&nbsp; **Reagan Udall Foundation for the FDA**  | &nbsp;&nbsp; **Board of directors from 2007 to 2021**  |
|  | National Institutes of Health  | &nbsp;&nbsp; Board of Foundation from 2010 to 2012 and the Science Management Review Board from 2010 to 2012  |
|  | Pharmaceutical Research and Manufacturers Association (PhRMA)  | &nbsp;&nbsp; Former Chairman of Science and Regulatory Executive Committee and the PhRMA Foundation Board  |

---

Celldex Therapeutics \| 11

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 1: Election of Directors

---

| | | |
|:---|:---|:---|
| **DENICE TORRES, 66**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Director** <br> since June 2025  | The Ignited Company  | &nbsp;&nbsp; Chief Executive Officer since 2017  |
| **PUBLIC BOARDS: <br> 2**  | Johnson & Johnson, Global Medical Device Business  | &nbsp;&nbsp; Chief Strategy and Transformation Officer from 2015 to 2017  |
| **COMMITTEES: <br> Compensation and Organization Development, Science and Commercialization**  | **Johnson & Johnson McNeil Consumer Healthcare**  | &nbsp;&nbsp; **President from 2011 to 2015**  |
| **EDUCATION:** <br> Bachelor of Science, Ball State University <br> J.D., Indiana University <br> M.B.A., University of Michigan <br> M.A. Study of Happiness, <br> Centenary University  | Johnson & Johnson Janssen Pharmaceuticals, Neuroscience  | &nbsp;&nbsp; President from 2009 to 2011  |
|  | Eli Lilly and Company  | &nbsp;&nbsp; Various Executive Positions from 1990 to 2004  |
|  | 2seventybio\*  | &nbsp;&nbsp; Board of directors from 2021 to 2025  |
|  | Glaukos Corporation\*  | &nbsp;&nbsp; Board of directors since 2021  |
|  | Karuna Therapeutics, Inc.  | &nbsp;&nbsp; Board of directors from 2020 to 2024  |
|  | Surface Oncology  | &nbsp;&nbsp; Board of directors from 2021 to 2023  |
|  | Bluebird bio, Inc.\*  | &nbsp;&nbsp; Board of directors from 2020 to 2021  |

---

12 \| Celldex Therapeutics

------

**[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

Information Regarding the Board of Directors and Corporate Governance

Independence of the Board of Directors

We are currently managed by a nine member Board of Directors, a majority of whom are "independent" as that term is defined in the applicable NASDAQ listing standards. Other than Mr. Marucci, each of our directors is deemed "independent" as that term is defined in the applicable NASDAQ listing standards. Our Board of Directors met five times in 2025. Each of the directors attended at least 75% of the aggregate of (i) the total number of meetings of our Board of Directors and (ii) the total number of meetings of all committees of our Board of Directors on which the Director served. Our annual meeting of stockholders is generally held to coincide with one of the Board's regularly scheduled meetings. We do not have a formal policy requiring members of the Board of Directors to attend our annual meetings, although our directors typically attend the annual meeting. Each of the then current directors attended the 2025 Annual Meeting of Stockholders. As of April 1, 2026, our committee membership has changed. The current members of our committees are listed below.

Board Leadership Structure

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| Number of Board meetings  | Number of Board meetings  | HARRY H. PENNER, JR  |  | ANTHONY S. MARUCCI  | Director Attendance  | Director Attendance  |
| 5  | 5  | Chair of the Board  |  | CEO/Director  | >75%  | >75%  |
| KEITH L. BROWNLIE  | CHERYL L. COHEN  | HERBERT J. CONRAD  | RITA I. JAIN, M.D.  | JAMES J. MARINO  | GARRY A. NEIL, M.D.  | Denice Torres  |
| Director  | Director  | Director  | Director  | Director  | Director  | Director  |

---

The Board recognizes that one of its key responsibilities is to evaluate and determine its optimal leadership structure so as to provide independent oversight of management. The Board understands that there is no single, generally accepted approach to providing Board leadership and that given the dynamic and competitive environment in which we operate, the right Board leadership structure may vary as circumstances warrant. Consistent with this understanding, the Nominating and Corporate Governance Committee considers the Board's leadership structure on an annual basis. This consideration includes the pros and cons of alternative leadership structures in light of the Company's operating and governance environment at the time, with the goal of achieving the optimal model for effective oversight of management by the Board. Currently, the roles of Chief Executive Officer and Chair of the Board are separate. Mr. Marucci, our Chief Executive Officer, is a member of our Board. Mr. Penner, an independent director, serves as our current Chair of the Board. The Board believes that its current leadership structure provides independent board leadership, engagement and oversight.

In addition, our independent committee chairs are responsible for leading committee meetings, determining committee meeting schedules, agenda and information flow, and reporting to the full Board on the committee's actions and areas of responsibilities.

Celldex Therapeutics \| 13

------**

[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

#### Role of the Board in Risk Oversight
Our management is responsible for assessing and managing risk and the Board of Directors oversees and reviews certain aspects of our risk management processes. The Board of Directors is involved in risk oversight through direct decision-making authority with respect to significant matters and the oversight of management and its committees. The Board is responsible for overseeing risks related to our overall operations and strategy, including, among others, product development, potential asset acquisitions, financial reporting, business continuity (including succession planning) and reputational risks faced by us.

The committees of the Board execute their oversight responsibility for risk management as follows:

---

| | |
|:---|:---|
| **Audit Committee**  | **Compensation and Organization <br> Development Committee**  |
| &nbsp;&nbsp;&nbsp; • Overseeing our internal financial and accounting controls and the work performed by the independent registered public accounting firm. <br>• Regularly discusses with management and the independent registered public accounting firm our major financial and controls-related risk exposures and steps that management has taken to monitor and control such exposures. <br>• Reviews our risk management insurance programs. <br>• Responsible for reviewing our information security programs, including cybersecurity. <br>• Our information technology ("IT") function provides regular updates to the Audit Committee on our IT security strategy, secure score assessments, penetration testing results, and status of risk mitigation activities, where applicable. IT also notifies the Audit Committee and our Executive Committee of any cybersecurity incidents (suspected or actual) and provides updates on the incidents as well as cybersecurity risk mitigation activities, as appropriate. <br>| &nbsp;&nbsp;&nbsp; • Responsible for overseeing risks related to our cash and equity-based compensation programs and practices. <br>• Periodically discusses with the President and Chief Executive Officer as well as the Board of Directors, as necessary, the compensation plan for both Executive Officers and the independent directors, performance goals and objectives for the period and related achievement, peer group and other relevant compensation benchmarks and practices and other matters to ensure our compensation practices are in our best interest and that of our shareholders. <br>• Has oversight responsibilities for our Diversity and Inclusion (D&I) initiatives. <br>|

---

---

| | |
|:---|:---|
| **Nominating and Corporate <br> Governance Committee**  | **Science and Commercialization <br> Committee**  |
| &nbsp;&nbsp;&nbsp; • Responsible for overseeing risks related to the composition and structure of the Board of Directors and its committees and our corporate governance. <br>• Assesses the qualifications and independence of members of the Board, makes annual recommendations regarding Board and committee membership, and reviews any transactions between us and our officers, directors, affiliates of officers and directors or other related parties for conflicts of interest. <br>| &nbsp;&nbsp;&nbsp; • Responsible for overseeing the scientific, regulatory and commercial aspects of our business. <br>• Monitor and review the overall strategy, direction and effectiveness of our research and development. <br>• Provide oversight and guidance regarding the commercial aspects of our business <br>|

---

14 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

#### Audit Committee

---

| | | |
|:---|:---|:---|
| **KEITH L. BROWNLIE <br> Chair**  | **JAMES J. MARINO**  | **GARRY NEIL, M.D.**  |
| MEETINGS IN 2025: **7**  | MEETINGS IN 2025: **7**  | MEETINGS IN 2025: **7**  |

---

• The Audit Committee makes recommendations concerning the engagement of our independent registered public accounting firm,

• Reviews with our independent registered public accounting firm the scope and results of the audit engagement,

• Approves professional services provided by our independent registered public accounting firm,

• Reviews the independence of our independent registered public accounting firm, considers the range of audit and non-audit fees, and

• Reviews the adequacy of our internal accounting controls.

• Oversee risks related to information technology and cybersecurity. Celldex mitigates its cybersecurity risk in many ways including leveraging standard industry tools from a software and hardware perspective, required annual training and maintaining a cybersecurity risk insurance policy. The Audit Committee reviews these information technology and cybersecurity risks at least annually.

Each member of the Audit Committee is "independent" as that term is defined in the rules of the Securities and Exchange Commission (the "SEC") and the applicable NASDAQ listing standards. The Board has determined that each Audit Committee member has sufficient knowledge in financial and auditing matters to serve on the Committee.

The Board has designated **Mr. Brownlie** as an "audit committee financial expert," as defined under the applicable rules of the SEC and the applicable NASDAQ listing standards. The Audit Committee met seven times during 2025. Our Board has adopted an Audit Committee Charter, which is available for viewing at www.celldex.com.

#### Compensation and Organization Development Committee

---

| | | |
|:---|:---|:---|
| **JAMES J. MARINO <br> Chair**  | **CHERYL L. COHEN**  | **DENICE TORRES**  |
| MEETINGS IN 2025: **8**  | MEETINGS IN 2025: **8**  | MEETINGS IN 2025: **8**  |

---

• To assist the Board in the establishment of compensation for the Chief Executive Officer,

• To approve the compensation of other officers and senior employees, and

• To approve certain other personnel and employee benefit matters.

• The Compensation and Organization Development Committee has oversight of the Company's strategies and policies related to human capital management, provided, however, that the full Board has retained oversight of the Company's strategies and policies related to diversity and inclusion.

Each member of the Compensation and Organization Development Committee is "independent" as that term is defined in the rules of the SEC and the applicable NASDAQ listing standards. The Compensation and Organization Development Committee met eight times during 2025. Our Board has adopted a Compensation and Organization Development Committee Charter, which is available for viewing at www.celldex.com.

Celldex Therapeutics \| 15

------

[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

#### Nominating and Corporate Governance Committee

---

| | | |
|:---|:---|:---|
| **GARRY NEIL, M.D. <br> Chair**  | **HERBERT J. CONRAD**  | **RITA JAIN, M.D.**  |
| MEETINGS IN 2025: **6**  | MEETINGS IN 2025: **6**  | MEETINGS IN 2025: **6**  |

---

• To assist the Board in reviewing, investigating and addressing issues regarding Board composition, policy and structure; membership on Board committees; and other matters regarding our governance.

Each member of the Nominating and Corporate Governance Committee is "independent" as that term is defined in the rules of the SEC and the applicable NASDAQ listing standards. The Nominating and Corporate Governance Committee met six times during 2025. Our Board has adopted a Nominating and Corporate Governance Committee Charter, which is available for viewing at www.celldex.com.

**Science and Commercialization Committee** (formerly referred to as the Science and Regulatory Committee)

---

| | | |
|:---|:---|:---|
| **CHERYL L. COHEN <br> Chair**  | **RITA JAIN, M.D.**  | **DENICE TORRES**  |
| MEETINGS IN 2025: **5**  | MEETINGS IN 2025: **5**  | MEETINGS IN 2025: **5**  |

---

• To assist the Board in the general oversight of the significant scientific and regulatory aspects of the Company's businesses.

• To assist the Board in the general oversight of and serve as a resource to management for the advancement of the Company's commercial strategy.

In April 2026, the Board changed the name of the Science and Regulatory Committee to the Science and Commercialization Committee to reflect that the Committee also provides oversight of the Company's commercial launch plans.

Each member of the Science and Commercialization Committee is "independent" as that term is defined in the rules of the SEC and the applicable NASDAQ listing standards. The Science and Commercialization Committee met five times during 2025. Our Board has adopted a Science and Commercialization Committee Charter, which is available for viewing at www.celldex.com.

#### Director Selection Criteria
The Nominating and Corporate Governance Committee is responsible for reviewing, on an annual basis, the appropriate mix of professional competencies, key attributes, skills and experiences required of board members to work together as a team to properly oversee our strategies and operations. The process followed by the Nominating and Corporate Governance Committee to evaluate any candidates, whether identified or recommended by board members, management, members of the Nominating and Corporate Governance Committee, stockholders or other external sources, includes meeting from time to time to evaluate biographical information and background material relating to potential candidates to the Board and interviews of selected candidates by members of the Committee and the Board. All nominees must have, at a minimum, high personal and professional integrity, exceptional ability and judgment, and effectiveness in collectively serving the long-term interests of all stockholders, all as described above. Other qualifications that may be considered are described in the Nominating and Corporate Governance Committee Charter. Our Nominating and Corporate Governance Committee and our Board value diversity and, as such, also consider diversity of gender, race, sexual orientation, national origin, education, professional experience and differences in viewpoints and skills when selecting members of our Board, however we have no formal policy regarding diversity of our Board of Directors.

All board members are expected to possess certain key attributes necessary to creating a functional board: high personal and professional ethics, integrity and values; practical wisdom and mature judgment; diversity of perspective, an inquisitive and objective perspective; professional experience at a policy-making level in business, government, education or medicine; time availability for in-person participation at board and committee meetings; and a commitment to representing the long-term interests of our stockholders. We look for directors with professional competencies that

16 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

include senior management operational experience, accounting and finance capabilities, deep industry-related experience, biologic development and manufacturing expertise, business development leadership, medical and scientific proficiencies, and government and public policy experience.

Independence is also an important selection criterion for nomination to our Board. Independent directors should be free of any relationship with us, our management, other directors or other parties that may impair, or appear to impair, the director's ability to make independent judgments. Independent directors must satisfy the criteria for independence established by NASDAQ. Currently all of our directors are independent except for our Chief Executive Officer, Mr. Marucci. There are no family relationships among our Director Nominees, management and other key personnel.

Finally, candidates should be enthusiastic and excited about their service on our Board and working collaboratively with existing board members to create value for all of our stockholders.

The Nominating and Corporate Governance Committee believes that the nine director nominees collectively have the skills, experience, diversity and character to execute the Board's responsibilities. The following is a summary of those qualifications:

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  | **ATTRIBUTES, EXPERIENCE AND SKILLS**  |
| <br> **DIRECTORS**  | **Industry <br> Experience**  | **Executive/<br>Leadership<br>Experience**  | **Scientific <br> Research/Drug <br> Development <br> Experience**  | **Business <br> Strategy/<br>Operations<br>Experience**  | **Financial <br> Experience**  | **Commercial <br> Experience**  | **Mergers & <br> Acquisitions <br> Experience**  | **Public <br> Company <br> Board <br> Experience**  |
| Anthony S. Marucci  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| Keith L. Brownlie  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| Cheryl L. Cohen  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| Herbert J. Conrad  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| Rita I. Jain, M.D.  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| James J. Marino  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| Garry A. Neil, M.D.  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| Harry H. Penner, Jr.  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  | ![[MISSING IMAGE: ic_tick-pn.gif]](ic_tick-pn.gif)  |
| **Denice Torres**  | | | | | | | | |

---

Over the past few years, our Nominating and Corporate Governance Committee implemented a process to expand our Board's scientific and commercial experience and focused on candidates with significant commensurate experience. This process resulted in the addition of highly qualified candidates to the Board. Our Nominating and Corporate Governance Committee's and our Board's priority in selecting Board members is the identification of persons who will provide a composite mix of experience, knowledge and abilities that will allow our Board to promote our strategic objectives and fulfill its responsibilities to our stockholders.

#### Stockholder Nominations for Directorships
Under our by-laws, stockholders wishing to suggest a candidate for director should write to the Secretary of Celldex at Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827. In order to give the Nominating and Corporate Governance Committee sufficient time to evaluate a recommended candidate and/or include the candidate in our proxy statement for the 2027 Annual Meeting, the recommendation should be received by our corporate secretary at our principal executive offices in accordance with our procedures detailed in the section below entitled "Submitting Proxy Proposals and Director Nominations for the 2027 Annual Meeting." Such submissions must state the nominee's name, together with appropriate biographical information and background materials, and information with respect to the stockholder or group of stockholders making the recommendation, including the number of shares of common stock owned by such

Celldex Therapeutics \| 17

------

[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

stockholder or group of stockholders, as well as other information required by our by-laws (including our proxy access bylaw). We may require any proposed nominee to furnish such other information as we may reasonably require to determine the eligibility of such proposed nominee to serve as an independent director or that could be material to a reasonable stockholder's understanding of the independence, or lack thereof, of such proposed nominee.

Assuming that appropriate information is provided for candidates recommended by stockholders, the Nominating and Corporate Governance Committee will evaluate those candidates by following substantially the same process, and applying substantially the same criteria, as for candidates submitted by Board members or other persons, as described above and as set forth in its written charter.

In addition, under our proxy access by-law, a stockholder (or a group of stockholders) who has owned at least 3% of the Company's outstanding common stock continuously for at least three (3) years and has complied with the other requirements of our by-laws may nominate up to the greater of two (2) individuals or 20% of the Board for inclusion in our proxy materials for election.

#### Stockholder Communications
The Board of Directors will give appropriate attention to written communications that are submitted by stockholders, and will respond if and as appropriate. Absent unusual circumstances or as contemplated by committee charters, and subject to advice from legal counsel, the Secretary of Celldex is primarily responsible for monitoring communications from stockholders and for providing copies or summaries of such communications to the Board of Directors as he considers appropriate.

Communications from stockholders will be forwarded to all directors if they relate to important substantive matters or if they include suggestions or comments that the Secretary considers to be important for the Board of Directors to know. Communication relating to corporate governance and corporate strategy are more likely to be forwarded to the Board of Directors than communications regarding personal grievances, ordinary business matters and matters as to which Celldex tends to receive repetitive or duplicative communications.

Stockholders who wish to send communications to the Board of Directors should address such communications to: The Board of Directors, Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827, Attention: Secretary.

#### Code of Business Conduct and Ethics
We have adopted a Code of Business Conduct and Ethics, as amended, that applies to our directors, officers and employees. The purpose of the Code of Business Conduct and Ethics is to promote, among other things, honest and ethical conduct and to ensure to the extent possible that our business is conducted in a consistently legal and ethical manner. Our Code of Business Conduct and Ethics includes standards of conduct including compliance with laws, antitrust, anti-corruption, gifts, lobbying, environmental compliance and conflicts of interest. Our Code of Business Conduct and Ethics is publicly available on our website at www.celldex.com. If we make any substantive amendments to the Code of Business Conduct and Ethics or grant any waiver, including any implicit waiver from a provision of the Code of Business Conduct and Ethics to our Directors or Executive Officers, we will disclose the nature of such amendments or waiver on our website or in a current report on Form 8-K. On March 14, 2023, our Board of Directors amended our Code of Business Conduct and Ethics which we included on our website.

Additionally, all Board members are expected to act in our best interests and the best interests of our stockholders and to avoid any conflicts of interest in accordance with our Code of Business Conduct and Ethics. In selecting director nominees, the Nominating and Corporate Governance Committee seeks individuals who are free from conflicts of interest.

#### Corporate Governance Matters
We have adopted a majority voting standard for uncontested elections of directors and eliminated the mandatory retirement age for directors. Since it is an uncontested election at this Annual Meeting, all director nominees are required to receive a number of "FOR" votes representing at least a majority of votes cast in the election. If such a director nominee fails to receive "FOR" votes representing at least a majority of votes cast and is an incumbent director, the by-laws require the director to promptly tender his or her resignation to the Board, subject to acceptance by the Board. The Nominating and Corporate Governance Committee of the Board would then be charged with making a recommendation to the Board as to whether to accept or reject the tendered resignation, or whether other action should be taken. In contested elections, where the number of nominees exceeds the number of directors to be elected, the plurality voting standard would continue to apply.

In addition, upon the recommendation of our Nominating and Corporate Governance Committee, we adopted corporate governance guidelines which are available for viewing at www.celldex.com.

18 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Information Regarding the Board of Directors and Corporate Governance

#### Compliance Program
Our Chief Financial Officer services as Compliance Officer under our Code of Business Conduct and Ethics, which governs ethical and legal decision-making in conducting our business and day to day operations. In addition, our General Counsel serves as Health Care Compliance Officer, who along with a Compliance Committee has oversight and responsibility for the Celldex Healthcare Compliance Program, which governs the Company's compliance with health care laws and regulations, including privacy. Our Compliance Program is designed to promote ethical business conduct and compliance with applicable laws and regulations. Key components of our compliance program include policies and procedures, compliance training and educational opportunities as appropriate, maintaining avenues for staff to raise concerns without fear of retaliation, including anonymously through a business conduct hotline, and responding appropriately to compliance-related events.

#### Stock Ownership Guidelines
Our Stock Ownership Guidelines for our directors and executive officers further align their financial interests with those of our stockholders, as well as promote sound corporate governance. For a detailed description of our Stock Ownership Guidelines see "Stock Ownership Policy — Employees" and "Stock Ownership Policy — Non-Employee Directors" below.

#### Insider Trading Policy (including Anti-Hedging and Anti-Pledging)
We have adopted an Insider Trading Policy that governs the purchase, sale and/or other dispositions of our securities that apply to all Company personnel, including directors, officers and employees, that we believe is reasonably designed to promote compliance with insider trading laws, rules and regulations and the exchange listing standards applicable to us. Additionally, our Insider Trading Policy prohibits all employees (including Executive Officers) and directors from engaging in short sales, transactions in put or call options, hedging transactions or similar inherently speculative transactions with respect to our stock at any time. For a detailed description of our Insider Trading Policy see www.celldex.com or refer to Exhibit 19.1 to our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 filed with the SEC on February 25, 2026.

Celldex Therapeutics \| 19

------

[**TABLE OF CONTENTS**](#TOC)

Sustainability & Corporate Responsibility

### Sustainability & Corporate Responsibility
The Board of Directors is committed to building a safe, environmentally sustainable, and ethical business that provides long-term value for all Celldex stakeholders. As part of this commitment, we support initiatives aligned to our mission, culture, and core values, including responsible environmental stewardship, community engagement, and strong corporate governance. These values provide the foundation for us to demonstrate our dedication to patients, employees, our environment, and local communities. Our Board oversees the sustainability and corporate responsibility initiatives relevant to our company and the associated risks.

#### Environmental
We view resource efficiency and responsible operations as core to maintaining a safe and compliant lab environment. We are committed to operating our facilities in an environmentally responsible way to reduce environmental impacts and protect our people, our business, the environment and the communities where we operate. In light of the potential impact our business may have on the environment, we have adopted a number of initiatives designed to eliminate, reduce, or substitute hazardous materials and waste and reduce water and energy consumption. Examples of these initiatives include:

---

| | | |
|:---|:---|:---|
| **ENVIRONMENTAL**  | **ENVIRONMENTAL**  | **GOVERNANCE**  |
| ![[MISSING IMAGE: ic_energystar-pn.jpg]](ic_energystar-pn.jpg)  | Continually replacing old equipment with Energy Star rated equipment to improve energy efficiency and reduce overall energy consumption  | &nbsp;&nbsp; We are committed to good corporate governance and to conducting our business in an ethical manner. We have in place numerous policies and guidelines to facilitate legal and ethical conduct and to further align the interests of our employees and directors with our stockholders and other key stakeholders, including the patients we serve. <br> For a detailed description of several of these policies and guidelines, see "Information Regarding the Board of Directors and Corporate Governance" above.  |
| ![[MISSING IMAGE: ic_led-pn.jpg]](ic_led-pn.jpg)  | Installing LED lighting with energy reducing controls systems to reduce overall energy use  | &nbsp;&nbsp; We are committed to good corporate governance and to conducting our business in an ethical manner. We have in place numerous policies and guidelines to facilitate legal and ethical conduct and to further align the interests of our employees and directors with our stockholders and other key stakeholders, including the patients we serve. <br> For a detailed description of several of these policies and guidelines, see "Information Regarding the Board of Directors and Corporate Governance" above.  |
| ![[MISSING IMAGE: ic_lowflow-pn.jpg]](ic_lowflow-pn.jpg)  | Installing low flow restroom fixtures  | &nbsp;&nbsp; We are committed to good corporate governance and to conducting our business in an ethical manner. We have in place numerous policies and guidelines to facilitate legal and ethical conduct and to further align the interests of our employees and directors with our stockholders and other key stakeholders, including the patients we serve. <br> For a detailed description of several of these policies and guidelines, see "Information Regarding the Board of Directors and Corporate Governance" above.  |
| ![[MISSING IMAGE: ic_waste-pn.jpg]](ic_waste-pn.jpg)  | Implementing business waste stream segregation for landfill and recyclables including paper, cardboard, bottles and cans  | &nbsp;&nbsp; We are committed to good corporate governance and to conducting our business in an ethical manner. We have in place numerous policies and guidelines to facilitate legal and ethical conduct and to further align the interests of our employees and directors with our stockholders and other key stakeholders, including the patients we serve. <br> For a detailed description of several of these policies and guidelines, see "Information Regarding the Board of Directors and Corporate Governance" above.  |

---

20 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Sustainability & Corporate Responsibility

#### Social
We believe much of our success is rooted in the diversity of our teams and that our business benefits from the different perspectives that a diverse workforce brings including background, experience, expertise and skills. We continue our commitment to diversity and inclusion by promoting a welcoming, diverse environment, including our partnership with the internal Employee Resource Group ("ERG"), which is open to all interested employees. The focus of the ERG has been on:

---

| | |
|:---|:---|
| ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | Providing education and resources to support employee learning about Diversity and Inclusion ("D&I")  |
| ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | Engaging in local community outreach to support D&I activities  |
| ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | Fostering a diverse and inclusive environment at Celldex  |
| ![[MISSING IMAGE: ic_tick-pn.jpg]](ic_tick-pn.jpg)  | Working toward a diverse talent pipeline for the biotechnology industry by engaging in local communities to provide exposure to biotechnology to students of all backgrounds  |

---

We are committed to greater data transparency, and that's why we are sharing our 2025 Federal Employer Information Report, known as EEO-1, as follows. These data are based on U.S. federal government requirements that categorizes roles into 10 job categories, each with seven race/ethnicity categories and two gender categories. While this is important data to collect and share, it does not fully reflect all of Celldex's job levels and titles and is not inclusive of all races, ethnicities and genders.

---

| | |
|:---|:---|
| **Senior Leadership (SVP or above)**  | **Senior Leadership (SVP or above)**  |
| ![[MISSING IMAGE: pc_seniorracial-pn.jpg]](pc_seniorracial-pn.jpg)  | ![[MISSING IMAGE: pc_seniorracial-pn.jpg]](pc_seniorracial-pn.jpg)  |
| **Full Time Workforce**  | **Full Time Workforce**  |
| ![[MISSING IMAGE: pc_fulltimedirectors-pn.jpg]](pc_fulltimedirectors-pn.jpg)  | ![[MISSING IMAGE: pc_fulltimeracial-pn.jpg]](pc_fulltimeracial-pn.jpg)  |

---

The Company's labor right policy provides for equal opportunity to all employees without regard to race, color, religion, sex (including gender, pregnancy, sexual orientation, gender identity and gender expression), national origin, disability, age, genetic information, ethnicity, citizenship status, participation in uniformed military services of the United States, or any other class or status protected by federal, state, or local law.

Celldex Therapeutics \| 21

------

[**TABLE OF CONTENTS**](#TOC)

Executive Officers

### Executive Officers
The following table sets forth certain information regarding our current Executive Officers:

---

| | | |
|:---|:---|:---|
| **ANTHONY S. MARUCCI**  | **TIBOR KELER, PH.D.**  | **SARAH CAVANAUGH**  |
| **President, Chief Executive <br> Officer and Director**  | **Executive Vice President and <br> Chief Scientific Officer**  | **Senior Vice President, Corporate <br> Affairs and Administration**  |
| Age: **64**  | Age: **67**  | Age: **51**  |
| **ELIZABETH CROWLEY**  | **MARGO HEATH-CHIOZZI, M.D.**  | **FREDDY JIMENEZ**  |
| **Senior Vice President and Chief <br> Product Development Officer**  | **Senior Vice President, <br> Regulatory Affairs**  | **Senior Vice President and <br> General Counsel**  |
| Age: **54**  | Age: **69**  | Age: **57**  |
| **TERI LAWVER**  | **SAM MARTIN**  | **RONALD PEPIN, PH.D.**  |
| **Senior Vice President and <br> Chief Commercial Officer**  | **Senior Vice President, Chief <br> Financial Officer and Secretary**  | **Senior Vice President and <br> Chief Business Officer**  |
| Age: **59**  | Age: **55**  | Age: **70**  |
| **DIANE C. YOUNG, M.D.**  |  |  |
| **Senior Vice President, <br> Chief Medical Officer**  |  |  |
| Age: **70**  |  |  |

---

---

| | | |
|:---|:---|:---|
| **ANTHONY S. MARUCCI, 64**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Founder, President and CEO** <br> Since September 2008 <br> (Director since December 2008)  | Celldex  | &nbsp;&nbsp; Former Vice President, Chief Financial Officer, Treasurer and Secretary  |
| **EDUCATION:** <br> M.B.A. from Columbia University and <br> M.H.L. from Brown University  | Medarex  | &nbsp;&nbsp; Treasurer (now a part of Bristol-Myers Squibb Co.) from December 1998 to March 2004 and senior financial positions from December 1998 to March 2003  |
|  | Genenta Science S.p.A.  | &nbsp;&nbsp; Board of directors from May 2021 to April 2024  |
|  | BioNJ Inc.  | &nbsp;&nbsp; Board of Trustees  |

---

---

| | | |
|:---|:---|:---|
| **TIBOR KELER, PH.D., 67**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Founder, Executive Vice President and Chief Scientific Officer** <br> Since 2014  | Celldex  | &nbsp;&nbsp; Senior Vice President and Chief Scientific Officer from March 2008 to July 2014 <br> Vice President, Research and Discovery and Chief Scientific Officer from May 2003 to March 2008  |
| **EDUCATION:** <br> Ph.D. in Microbiology from the <br> University of Pennsylvania  | Medarex  | &nbsp;&nbsp; Senior Director of Preclinical Development and Principal Scientist from September 1993 to March 2004  |

---

22 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Officers

---

| | | |
|:---|:---|:---|
| **SARAH CAVANAUGH, 51**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President, Corporate <br> Affairs and Administration** <br> Since 2017  | Celldex  | &nbsp;&nbsp; Vice President, Investor Relations and Corporate Communications from August 2012 to June 2017  |
| **Senior Vice President, Corporate <br> Affairs and Administration** <br> Since 2017  | **MacDougall Biomedical <br> Communications**  | &nbsp;&nbsp; **Vice President from 2007 to 2012**  |
| **EDUCATION:** <br> B.A. from the University of <br> New Hampshire  | Point Therapeutics, Inc.  | &nbsp;&nbsp; Former Director of Corporate Communications  |
| **EDUCATION:** <br> B.A. from the University of <br> New Hampshire  | Fallon Community Health Plan  | &nbsp;&nbsp; Former Director of Corporate Communications  |
| **EDUCATION:** <br> B.A. from the University of <br> New Hampshire  | American Cancer Society  | &nbsp;&nbsp; Various former positions including Division Communications and Marketing Director for the Mid-South Division  |

---

---

| | | |
|:---|:---|:---|
| **ELIZABETH CROWLEY, 54**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President and Chief <br> Product Development Officer** <br> Since 2016  | Celldex  | &nbsp;&nbsp; Senior Vice President, Product Development from July 2014 to August 2016 <br> Vice President, Clinical Development from 2009 to July 2014  |
| **EDUCATION:** <br> B.S. in Chemistry with a concentration <br> in Business from Boston College  | CuraGen Corporation  | &nbsp;&nbsp; Held several senior level roles, most recently serving as the Vice President of Development Operations  |
|  | Bayer Corporation  | &nbsp;&nbsp; Held several roles in clinical research and project management, most recently serving as the Director of Global Study Audit Management  |

---

---

| | | |
|:---|:---|:---|
| **MARGO HEATH- <br> CHIOZZI, M.D., 69**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President, <br> Regulatory Affairs** <br> Since 2017  | Bristol-Myers Squibb Company  | &nbsp;&nbsp; Served as Executive Director, Global Regulatory Sciences; Vice President, Global Regulatory Strategy; and Vice President, Global Submissions and Regulatory Policy from 2003 until September 2017  |
| **EDUCATION:** <br> B.S. and M.D. from the University of Utah. She received further medical training in internal medicine at Duke University and completed fellowships in infectious <br> disease at Brigham & Women's Hospital <br> and Dana-Farber Cancer Institute in <br> Boston  | Abbott Laboratories  | &nbsp;&nbsp; Served as Medical Director, Pharmacogenetics; Senior Director, Global Marketed Product Development and Outcomes Research; and Global Project Head, Abbott/Millennium Obesity/Diabetes Alliance from 1995 to 2003  |
|  | **University of Hawaii John A. Burns School of Medicine**  | &nbsp;&nbsp; **Former Assistant Professor**  |
|  | Queen's Medical Center  | &nbsp;&nbsp; Former Director of the HIV Research Clinical  |
|  | Kapiolani Medical Center  | &nbsp;&nbsp; Former Director of the Women's Immunology Clinical for Women and Children, in Honolulu  |

---

Celldex Therapeutics \| 23

------

[**TABLE OF CONTENTS**](#TOC)

Executive Officers

---

| | | |
|:---|:---|:---|
| **FREDDY JIMENEZ, 57**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President and <br> General Counsel** <br> Since 2021  | Celldex  | &nbsp;&nbsp; Vice President, Law and Compliance from February 2016 to December 2020  |
| **EDUCATION:** <br> B.A. in Biology and Certificate in the <br> Legal Studies Program from Brandeis University and his legal training and JD <br> from the Rutgers School of <br> Law — Newark.  | Johnson & Johnson  | &nbsp;&nbsp; Assistant General Counsel, Senior Counsel and General Attorney from 1999 to 2016 <br> FDA Liaison for the R.W. Johnson Pharmaceutical Research Institute (a Johnson & Johnson Company) and varying roles of increasing seniority in regulatory affairs and clinical research from 1991 to 1997  |
|  | &nbsp;&nbsp;&nbsp; **Akin Gump Strauss Hauer & Feld LLP**  | &nbsp;&nbsp; Associate in the Food and Drug Practice from 1997 to 1999  |

---

---

| | | |
|:---|:---|:---|
| **TERI LAWVER, 59**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President and Chief Commercial Officer** <br> Since 2025  | Thera Lifescience Advisors LLC  | &nbsp;&nbsp; Principal and Owner from April 2025 to November 2025  |
| &nbsp;&nbsp; **EDUCATION:** <br> Masters of Business Administration, Duke University Fuqua School of Business, 1994 <br> Bachelor of Science Degree, Linguistics <br> Georgetown University, 1989  | Dexcom Corporation  | &nbsp;&nbsp; Strategic Advisor from December 2024 to March 2025 <br> EVP and Chief Commercial Officer from January 2023 to November 2024  |
|  | Johnson & Johnson Corporation  | &nbsp;&nbsp; General Management and Commercial Leadership Roles of Increasing Responsibility, including: Worldwide Vice President, Immunology: January 2017 to December 2023 <br> Global Vice President, Cardiovascular and Metabolism from July 2013 to December 2016 <br> President, J&J Medical Companies Canada from April 2011 to July 2013 <br> Worldwide General Manager, Animas Corporation from October 2007 to April 2011 <br> National Sales Director, Corporate Accounts, Centocor from January 2006 to December 2007 <br> Senior Director, Gastroenterology Marketing from May 2002 to January 2006  |
|  | McKinsey & Company  | &nbsp;&nbsp; Associate Principal <br> Engagement Manager <br> Consultant  |

---

24 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Officers

---

| | | |
|:---|:---|:---|
| **SAM MARTIN, 55**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President, Chief Financial Officer and Secretary** <br> Since 2017  | Celldex  | &nbsp;&nbsp; Vice President, Finance from January 2015 to July 2017 <br> Senior Director of Finance from August 2011 to January 2015 <br> Director of Financial Reporting, Planning and Analysis from 2009 to 2011  |
| **EDUCATION:** <br> M.B.A. from Boston University, <br> a B.S. from Skidmore College and is a Certified Public Accountant  | Alseres Pharmaceuticals, Inc.  | &nbsp;&nbsp; Held several former roles, most recently served as Director of Finance and Corporate Compliance  |
|  | Ernst & Young LLP  | &nbsp;&nbsp; Held several former roles, most recently serving as Audit Manager  |

---

---

| | | |
|:---|:---|:---|
| **RONALD PEPIN, PH.D., 70**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President and <br> Chief Business Officer** <br> Since 2011  | Shire Pharmaceuticals  | &nbsp;&nbsp; Vice President from June 2010 to April 2011  |
| **EDUCATION:** <br> B.A. from Tufts University and <br> Ph.D. in Genetics from Georgetown <br> University  | Medarex  | &nbsp;&nbsp; Senior Vice President, Business Development from August 2000 to December 2009  |
|  | Bristol-Myers Squibb Company  | &nbsp;&nbsp; Former Executive Director of External Science and Technology  |

---

---

| | | |
|:---|:---|:---|
| **DIANE C. YOUNG, M.D., 70**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  | &nbsp;&nbsp;&nbsp; **CAREER HIGHLIGHTS**  |
| **Senior Vice President, <br> Chief Medical Officer** <br> Since 2019  | GTx, Inc  | &nbsp;&nbsp; Vice President, Chief Medical Officer from July 2015 until February 2019  |
| **EDUCATION:** <br> A.B. in Biochemical Sciences from Harvard University and her M.D. from Harvard Medical School. Medical training in internal medicine at Johns Hopkins Hospital and Vanderbilt University Hospital and completed a fellowship in medical oncology at Dana-Farber Cancer Institute.  | Novartis Oncology  | &nbsp;&nbsp; Vice President, Head of Oncology Clinical Development and Medical Affairs, Latin America and Canada; Vice President, Global Head of Medical Affairs, Oncology Business Unit; and Vice President, Global Head of Clinical Development Phase 2/3, Oncology Business Unit from 2002 to June 2015  |
|  | R.W. Johnson Pharmaceutical <br> Research Institute  | &nbsp;&nbsp; Held roles including Vice President for Global Development and Senior Director, Clinical Research and Development from 1993 to 2002  |
|  | Sandoz Research Institute  | &nbsp;&nbsp; Held roles at Director of Clinical Research, Cytokine Development Unit and Associate Medical Director from 1991 to 1993  |
|  | Hoffman-LaRoche, Inc.  | &nbsp;&nbsp; Assistant Director, Clinical Investigation II from 1988 to 1990  |

---

Celldex Therapeutics \| 25

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

### Executive Compensation

#### Compensation Discussion and Analysis

#### Introduction
Our Compensation and Organization Development Committee oversees and administers our executive compensation programs. The Committee's complete roles and responsibilities are set forth in the written charter of the Compensation and Organization Development Committee adopted by our Board of Directors, which can be found at our website, www.celldex.com.

#### Overview
Our executive compensation programs are designed to deliver compensation that allows us to attract and retain superior talent who can perform effectively and succeed in a demanding business environment and that is competitive with our peer group. Our compensation programs are also designed to reward performance against pre-established goals and align the interests of our executives with our stockholders. We believe that the compensation of our Executive Officers should focus executive behavior on the achievement of near-term corporate targets as well as long-term business objectives and strategies. We believe that pay-for-performance compensation programs, which reward our executives when they achieve individual and/or corporate goals, create stockholder value and thus have emphasized company and individual performance in setting compensation. We use a combination of base salary, annual cash incentive compensation programs, a long-term equity incentive compensation program and a broad-based benefits program to create a competitive compensation package for our executive management team.

We describe below our compensation philosophy, policies and practices with respect to our (i) Chief Executive Officer, (ii) Chief Financial Officer, and (iii) three most highly compensated Executive Officers, other than the Chief Executive Officer and Chief Financial Officer, who were serving as Executive Officers as of December 31, 2025, collectively referred to as our Named Executive Officers. In 2025, our Named Executive Officers were as follows:

---

| | | |
|:---|:---|:---|
| **ANTHONY S. MARUCCI**  | | **TIBOR KELER, PH.D.**  |
| **President, <br> Chief Executive Officer and <br> Director**  | | **Executive Vice President <br> and Chief Scientific Officer**  |
| **ELIZABETH CROWLEY**  | **MARGO HEATH-CHIOZZI, M.D.**  | **SAM MARTIN**  |
| **Senior Vice President, <br> Chief Product Development <br> Officer**  | **Senior Vice President, <br> Regulatory Affairs**  | **Senior Vice President, <br> Chief Financial Officer and <br> Secretary**  |

---

We establish corporate goals that are designed to contribute to the development of our lead programs, ensure that we manage our cash effectively and have sufficient funding to complete near-term development activities for our lead drug candidates and, where appropriate, to pursue partnerships and collaborations through which we can leverage the value of our drug candidates. We seek to link the financial interests of our Named Executive Officers to those of our stockholders by tying compensation to the achievement of these strategic corporate goals, which we believe will drive long-term stockholder value. Each year we establish corporate goals, the achievement of which we believe is essential to the long-term success of our business.

The Compensation and Organization Development Committee has adopted a compensation philosophy that considers each executive's experience, scope of position, individual performance and company constraints and reviews the executive compensation of our peer group and the Aon Global Life Sciences ("Aon") Survey results. In June 2025, the Compensation and Organization Development Committee increased the annual base salary for Mr. Marucci, Dr. Keler, Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin by 4.0% to 6.0%. In December 2025, the Compensation and Organization Development Committee increased the annual base salary for Mr. Marucci, Dr. Keler, Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin by 1.4% to 4.6%. The December 2025 market adjustment followed an analysis of independent benchmarking data of peer companies as the Company prepares for potential commercialization with a view to make compensation competitive and retain a high performing management team.

In December 2025 and January 2026, our Compensation and Organization Development Committee reviewed our performance relative to our 2025 corporate goals. Our corporate goals cover priorities important to both our short and long-term success. The Committee considers both quantitative and qualitative results and applies discretion when evaluating performance and determining total bonus payout potential. Based on its evaluation of our performance against our strategic goals, including the achievement of stretch goals, the Committee determined a payout factor of 100% of the target.

26 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

In 2025, we accomplished the following significant milestones during the year:

---

| |
|:---|
| **Strong execution across the barzolvolimab clinical program:**  |
| In 2025, we made significant progress across the barzolvolimab development program, including strong execution across our Phase 3 chronic spontaneous urticaria (CSU) studies that supported enrollment completion six months ahead of guidance in February 2026, the initiation of our Phase 3 program in Cold Urticaria (ColdU) and Symptomatic Dermographism (SD) and the reporting of multiple positive data sets, including best-in-disease data from Phase 2 studies in both CSU and ColdU/SD. <br> The global Phase 3 program in CSU consists of two Phase 3 trials (EMBARQ-CSU1 and EMBARQ-CSU2) and enrollment is complete. The studies are designed to establish the efficacy and safety of barzolvolimab in adult patients with CSU who remain symptomatic despite H1 antihistamine treatment and also include patients who remain symptomatic after treatment with biologics. EMBARQ-CSU1 and EMBARQ-CSU2 enrolled 1,939 patients — the largest program conducted in antihistamine refractory CSU, including patients with advanced therapy experienced/refractory CSU. The studies included 43 countries and over 500 sites. Topline data from the study is expected in the fourth quarter of 2026. <br> Based on results from the completed Phase 2 study of barzolvolimab in CSU, we believe barzolvolimab has the potential to deliver a first-in-class and best-in-disease clinical profile — symptom free complete control and dramatic improvements in quality of life and angioedema. The primary endpoint of the study was met, a statistically significant mean change from baseline to week 12 in UAS7 (weekly urticaria activity score), across all dose levels and all secondary endpoints were also met. Up to 51% of patients on study had a complete response and were symptom free (UAS7=0; no itch/no hives) at 12 weeks, which continued to deepen over 52 weeks of active therapy to up to 71% of patients. In 2025, we reported data that demonstrated that this profound clinical benefit continued even after patients were off therapy with up to 41% of patients reporting complete response seven months after receiving their last dose. This sustained off-treatment efficacy was observed despite barzolvolimab clearance and normalization of tryptase (a measure of mast cell burden), suggesting disease modification and supports barzolvolimab's significant potential to become a transformative treatment option for patients suffering from CSU. Patients also reported dramatic improvements in angioedema control and quality of life. At 12 weeks, up to 65% of barzolvolimab treated patients were angioedema free (AAS7=0), which increased to up to 77% at Week 52 and remained at up to 64% seven months after last dose. At 12 weeks, up to 67% of patients treated with barzolvolimab reported their CSU had no impact on their quality of life (DLQI 0/1), which increased to up to 82% at Week 52 and remained at up to 48% seven months after last dose. <br> The global Phase 3 program in ColdU and SD (EMBARQ-ColdU and SD) opened to enrollment in December 2025 and enrollment is ongoing. The study is designed to establish the efficacy and safety of barzolvolimab in adult participants with ColdU and SD who remain symptomatic despite H1 antihistamine treatment. Participants who remain symptomatic after treatment with biologics are also eligible for the study. The Phase 3 study will recruit approximately 240 participants (120 ColdU; 120 SD) from approximately 75 clinical trial sites across 7 countries. <br> In 2025, we completed our Phase 2 study in ColdU and SD. Barzolvolimab is the first drug to demonstrate clinical benefit in patients with these conditions in a large, randomized, placebo-controlled study, meeting all primary and secondary endpoints at both 12 and 20 weeks. Up to 53.1% of patients with ColdU and 57.6% of patients with SD treated with barzolvolimab experienced a complete response (per provocation test) compared to placebo rates of only 12.5% (p=0.0011) in ColdU and 3.2% (p<0.0001) in SD. In November 2025, we reported that these effects were sustained through the end of the treatment period (20 weeks) with up to 78% of patients with ColdU and 58% of patients with SD obtaining a partial or complete response. Marked and rapid improvement in quality of life was also observed and sustained through the 20-week period with up to 60% of patients reporting that disease symptoms no longer impacted their QOL at Week 20. Patients were followed for up to 24 weeks after treatment completion and patients with returning or continuing symptoms were given the option to enter an open label extension (OLE) during this follow up period. Consistent with the clinical endpoint results at Week 20, placebo-treated patients entered the OLE at a faster rate compared to barzolvolimab-treated patients. In March of 2026, data from the OLE were presented demonstrating barzolvolimab retreatment achieves similar profound efficacy to first exposure in patients with ColdU and SD further supporting barzolvolimab's first-in-class and best-in-disease profile. <br> We continued to execute across the Phase 2 studies of barzolvolimab in patients with eosinophilic esophagitis (EOE), prurigo nodularis (PN) and atopic dermatitis (AD) in 2025. Data from the EOE study were presented in August 2025. The study met the primary endpoint demonstrating barzolvolimab's ability to potently deplete mast cells in the gastrointestinal tract. The depletion of mast cells did not result in improved clinical outcomes providing direct evidence that mast cells are not a primary driver in EoE. Based on these results, Celldex did not advance development in EoE but will consider future development with KIT- or SCF-targeted therapies in other GI indications where mucosal mast cells are believed to play an important role. Enrollment to the Phase 2 studies in PN and AD is complete and topline data from these programs are expected in summer 2026 and late 2026, respectively. <br> Barzolvolimab has demonstrated a well-tolerated safety profile across all studies reported to date.  |

---

Celldex Therapeutics \| 27

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

---

| |
|:---|
| **Continued progress across our bispecific platform:**  |
| Our next generation bispecific antibody platform is supporting the expansion of our pipeline with additional candidates for inflammatory diseases. Targets are being selected based on new science as well as their compatibility to be used in bispecific antibody formats with our existing antibody programs. Development is focused on emerging, important pathways controlling inflammatory diseases. <br> CDX-622, the first candidate, targets two complementary pathways that drive chronic inflammation, potently neutralizing the alarmin thymic stromal lymphopoietin (TSLP) and depleting mast cells via stem cell factor (SCF) starvation. In November 2024, a multi-part Phase 1 dose-escalation study in healthy volunteers was initiated and enrollment was completed across all parts in January 2026. Positive data from the single ascending dose portion of the study was presented in October 2025 demonstrating a favorable safety and pharmacokinetic profile and sustained mast cell inhibition. Data from the multiple ascending dose portion of the study and subcutaneous administration are anticipated in the third quarter of 2026. In January 2026, we initiated an open-label, single-dose Phase 1 proof of mechanism study in adults with mild to moderate asthma.  |

---

---

| | |
|:---|:---|
| **Fund the continued development of our clinical and preclinical programs and the overall operation of our <br> business:**  | **Fund the continued development of our clinical and preclinical programs and the overall operation of our <br> business:**  |
| We ended 2025 with cash, cash equivalents and marketable securities of $519 million which is sufficient to meet estimated working capital requirements and fund current planned operations through 2027.  | **$519M**  |

---

---

| |
|:---|
| **Execute across Diversity and Inclusion (D&I) initiatives:**  |
| In 2025, we continued our commitment to diversity and inclusion by promoting a welcoming, diverse environment, including our partnership with the internal Employee Resource Group (ERG). The ERG continued to focus their efforts on hosting local urban high school and college STEM students for experiential learning in biotechnology and delivering various employee educational programs at Celldex.  |

---

#### Independent Compensation Consultants
The Compensation and Organization Development Committee believes that independent advice is important in developing Celldex's director and executive compensation programs and engages Aon's Human Capital Solutions practice, a division of Aon plc, as its independent compensation consultant. Aon reports directly to the Compensation and Organization Development Committee and provides guidance on trends in executive and non-employee director compensation, the development of specific executive compensation programs, the composition of the Company's compensation peer group and other matters as directed by the Compensation and Organization Development Committee. The Company also participated in various Aon surveys in 2025. In 2025, Aon did not provide any other services to Celldex. The Compensation and Organization Development Committee has assessed the independence of Aon and concluded that no conflict of interests exists under applicable NASDAQ and SEC rules.

#### Data Used to Make Compensation Determinations
In making decisions regarding the compensation of our Executive Officers, the Compensation and Organization Development Committee generally considers compensation and survey data for similarly situated executives at a comparison group of companies it considers our peer group as a reference point. These comparison data are primarily used to gauge the reasonableness and competitiveness of executive compensation decisions, but are not used to set compensation formulaically.

We draw upon a pool of talent that is highly sought after by large and established pharmaceutical and biotechnology companies as well as other development-stage life science companies, both within and outside our geographic areas. We believe that the compensation practices of our industry in general and of our select peer group in particular provide useful information to help us establish compensation practices that allow us to attract, reward, motivate and retain a highly talented executive team. We believe we must offer a compensation package to all of our officers and our other employees that is competitive with our peer group, as well as larger pharmaceutical and biotechnology companies from whom we frequently draw talent. In addition, the comparator companies should be aligned with our current stage of development and have similar short and long-term growth objectives. The Compensation and Organization Development Committee's pay for performance philosophy considers the compensation of our peer group when assessing total executive

28 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

compensation and other key factors related to compensation including but not limited to overall job scope/span, performance, impact to corporate goals, tenure and market dynamics to set individual compensation. The Committee reviews and adjusts compensation as appropriate over the course of the year.

We review the cash, equity and total compensation for all comparable officers in our peer group relative to the elements of compensation paid to our officers. In considering how these data relate to our existing compensation structure, we also take into account our size, stage of development, performance and geographic location as compared to these peer companies, as well as what we know about the comparable scope of responsibilities of our officers versus those of comparable executives at such peer group companies. We used two primary market frames of reference (which we refer to as the "market") against which to compare our total executive compensation practices and levels and inform our decisions regarding compensation of our officers as follows:

• Select Peer Group — A select group of national biotechnology companies at a similar stage of development as our company with similar headcount, R&D expense, market capitalization and in most cases, similar therapeutic targets, and

• Aon Global Life Sciences Survey — A national survey of executive compensation levels and practices that covers approximately sixty executive positions in over 600 multinational life sciences organizations.

We do not apply a specific weighting to either data source when making compensation comparisons. Instead, we develop competitive market guidelines using these data sources.

We review our peer group each year to ensure continued relevance as we grow and develop, and the Compensation and Organization Development Committee approves our peer group prior to its adoption. In March 2024, the below peer group was approved by the Compensation and Organization Development Committee and used to inform our decisions affecting executive compensation in 2024. In March 2024, this peer group consisted of public companies in the biopharmaceutical industry with product candidates generally in mid to late-stage development, with employee headcount 50<sup>th</sup> percentile of 341 (range of 112 to 904), R&D expense 50<sup>th</sup> percentile of $301 million and market capitalization 50<sup>th</sup> percentile of $3.6 billion.

In December 2024, the Compensation and Organization Development Committee decided to keep our 2025 peer group consistent with the 2024 peer group based on the consistency of our stage of development from year to year. Our Compensation and Organization Development Committee believes that, as of December 2024, this list continued to be representative of the companies with whom we generally compete for talent.

---

| | |
|:---|:---|
| Apellis Pharmaceuticals | Iovance Biotherapeutics |
| Arcellx | Keros Therapeutics |
| Arvinas | Kiniksa Pharmaceuticals |
| Biohaven | Madrigal Pharmaceuticals |
| Blueprint Medicines | Morphic |
| BridgeBio Pharma | Protagonist Therapeutics |
| CRISPR Therapeutics | Roivant Sciences |
| Cytokinetics | SpringWorks Therapeutics |
| Denali Therapeutics | Syndax Pharmaceuticals |
| ImmunityBio | Vaxcyte |
| Immunovant | Vir Biotechnology |
| Inhibrx | Zentalis Pharmaceuticals |

---

#### Administration and Objectives of Our Executive Compensation Program
The Compensation and Organization Development Committee of the Board of Directors, which comprises independent, non-employee directors, is responsible for establishing and administering the policies governing the compensation of our Executive Officers, including salary, bonus and stock option grants. The policy of the Compensation and Organization Development Committee is to compensate our Executive Officers with competitive salaries based on their level of experience and job performance. All Executive Officers are eligible for annual bonus awards based on achievement of our strategic corporate goals and participation in our stock option program. Stock option grants are made in accordance with our 2021 Incentive Plan. Prior to the approval of the 2021 Incentive Plan, stock option grants were made in accordance with our 2008 Stock Option and Incentive Plan, as amended and restated (the "2008 Incentive Plan"). The Compensation and Organization Development Committee is also responsible for the administration of our 2004 Employee Stock Purchase Plan, as amended (the "2004 Plan"), in which employees participate on a voluntary basis.

Celldex Therapeutics \| 29

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

Our Compensation and Organization Development Committee has designed our overall executive compensation program to achieve the following objectives:

• attract and retain talented and experienced executives;

• motivate and reward executives whose knowledge, skills and performance are critical to our success;

• provide a competitive compensation package that aligns the interests of our executive officers and stockholders by including a significant variable component which is weighted heavily towards performance-based rewards, based upon achievement of predetermined goals;

• ensure fairness among the executive management team by recognizing the contributions each executive makes to our success;

• foster a shared commitment among executives by aligning our and their individual goals; and

• compensate our executives to manage our business to meet our near-term and long-term objectives.

We use a mix of short-term compensation (base salaries and cash incentive bonuses) and long-term compensation (equity incentive compensation) to provide a total compensation structure that is designed to achieve these objectives. We determine the percentage mix of compensation structures that we think is appropriate for each of our Executive Officers. In general, the Compensation and Organization Development Committee believes that a substantial percentage of the compensation of our Executive Officers should be performance based. We consider stock options that vest over time an appropriate choice of long-term incentive given the development stage of the Company. The Compensation and Organization Development Committee uses its judgment, experience, relative peer group data and the recommendations of the Chief Executive Officer (except for his own compensation) to determine the appropriate mix of compensation for each Executive Officer.

In determining whether to adjust the compensation of any of our Named Executive Officers, we take into account the changes, if any, in the following:

• market compensation levels;

• the contributions made by each Executive Officer;

• the performance of each Executive Officer;

• the increases or decreases in responsibilities and roles of each Executive Officer;

• the business needs of the Company with respect to each Executive Officer;

• the relevance of each Executive Officer's experience to other potential employers; and

• the readiness of each Executive Officer to assume a more significant role within the organization.

In addition, with respect to new Executive Officers, we take into account their prior base salary and annual cash incentives, their expected contribution and our business needs. We believe that our executive officers should be fairly compensated each year relative to market pay levels within our industry.

#### Committee Consideration of the Company's 2025 Shareholder Advisory Vote on Executive Compensation
![[MISSING IMAGE: pc_sharevoted-pn.jpg]](pc_sharevoted-pn.jpg) <br>

At our 2025 Annual Meeting of Shareholders, approximately 99% of the shares voted at the meeting approved, on an advisory basis, the compensation of the Named Executive Officers. Given that a majority of the shares voted approved the 'say on pay' advisory proposal, the Committee did not implement specific changes and continued with its performance-based compensation philosophy and its balanced approach to various components of its compensation program. However, the Compensation and Organization Development Committee does monitor the results of the annual advisory 'say-on-pay' proposal and refers to such results as one of many factors considered in connection with the discharge of its responsibilities, although the Committee does not assign a quantitative weighting to any such factors.

At our 2023 annual meeting of stockholders, we conducted a non-binding stockholder vote on the frequency of future Say-on-Pay votes. We recommended that such votes be conducted annually and our stockholders overwhelmingly approved that recommendation. We listen to the views of shareholders and receive valuable commentary and insights from them. We believe that our executive compensation program is aligned with structures and the components sought by our shareholders and the practices of our peer companies. We believe that our program is effective at motivating our Executive Officers to achieve our goals.

30 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

The Compensation and Organization Development Committee and the Board are committed to continually evaluating changes to the compensation program that will enhance the link between our long-term strategy and objectives and the incentives for our Executive Officers and enhancing alignment between our Executive Officers' and our shareholders' interests.

#### Executive Compensation Components
In order to both attract and retain experienced and qualified executives to manage us, the Compensation and Organization Development Committee's policy on executive compensation is to (i) pay salaries which are competitive with the salaries of executives in comparable positions in the biotechnology industry, and (ii) allow for additional incentive-based compensation through the payment of annual cash bonuses and the grant of stock-based incentive awards. This policy is designed to have a significant portion of each executive's total compensation be tied to our progress in order to incentivize the executive to fully dedicate himself or herself to achievement of corporate goals and align the executive's interest with those of our stockholders.

Our executive compensation program is primarily composed of base salary, incentive cash compensation payable on an annual basis and equity compensation. In addition, we provide our executives with benefits that are generally available to our salaried employees, including medical, dental, group life and accidental death and dismemberment insurance, short and long-term disability coverage and our 401(k) plan. Within the context of the overall objectives of our compensation programs, we determined the specific amounts of compensation to be paid to each of our executives in 2025 based on a number of factors including:

• the roles and responsibilities of our executives;

• the individual experience and skills of, and expected contributions from, our executives;

• the amounts of compensation being paid to our other executives;

• our executives' historical compensation; and

• our understanding of the amount of compensation generally paid by similarly situated companies to their executives with similar roles and responsibilities.

We discuss each of the primary elements of our executive compensation in detail below. While we have identified particular compensation objectives that each element of executive compensation serves, our compensation programs complement each other and collectively serve all of our executive compensation objectives described above.

*Base Salary* 

Each Executive Officer (except the Chief Executive Officer whose performance is reviewed by the Compensation and Organization Development Committee) has an annual performance review with the Chief Executive Officer who makes recommendations on salary increases, promotions, cash bonuses and stock option grants to the Compensation and Organization Development Committee. We have historically established base salaries for each of our executives based on many factors, including average salary increases expected in the biotechnology industry in the Boston, Massachusetts, New Haven, Connecticut and central New Jersey areas, competition in the marketplace to hire and retain executives, experiences of our leadership team with respect to salaries and compensation of executives in similarly situated companies in our industry and other similar industries, as well as additional factors which we believe enable us to hire and retain our leadership team in an extremely competitive environment. Our Compensation and Organization Development Committee at least annually reviews salary ranges and individual salaries for our Executive Officers and approved the following salaries for our Named Executive Officers:

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Annual Salary**  | **Annual Salary**  | | |
| **Name**  | **As of <br> December 31, <br> 2025**  | **As of <br> December 31, <br> 2024**  | **Increase <br> $**  | **Increase <br> %**  |
| Anthony S. Marucci | $822000 | $769611 | $52389 | 6.8%  |
| Tibor Keler, Ph.D. | $574276 | $542573 | $31703 | 5.8%  |
| Elizabeth Crowley | $498000 | $463059 | $34941 | 7.5%  |
| Margo Heath-Chiozzi, M.D. | $501000 | $475069 | $25931 | 5.5%  |
| Sam Martin | $529000 | $477240 | $51760 | 10.8%  |

---

Celldex Therapeutics \| 31

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

*Annual Performance-Based Cash Bonus* 

We have designed our annual cash bonuses to reward our Executive Officers for their individual performance and contributions to our corporate goals for each year, as approved in advance by our Compensation and Organization Development Committee and Board of Directors. The corporate goals are allocated between specific product and financial performance targets. Achievement of our corporate goals was, in 2025, the primary factor considered by our Compensation and Organization Development Committee in determining the annual bonuses for our Executive Officers. However, the Compensation and Organization Development Committee retains discretion to adjust any individual bonus based on assessment of such individual's performance. Our performance-based bonus plan emphasizes the contributions of each of our Executive Officers to the achievement of our corporate goals.

At the beginning of each calendar year, the Compensation and Organization Development Committee establishes annual corporate performance goals and target bonuses. The Compensation and Organization Development Committee has established target bonuses for each of our Named Executive Officers including 60% of base salary for Mr. Marucci, 45% of base salary for Dr. Keler, and 40% of base salary for Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin. In December 2025, the Compensation and Organization Development Committee established new target bonuses for each of our Named Executive Officers including 65% of base salary for Mr. Marucci, 53% of base salary for Dr. Keler, and 45% of base salary for Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin, in each case applicable to the entire year 2025. The December 2025 market adjustment followed an analysis of independent benchmarking data of peer companies as the Company prepares for potential commercialization with a view to make compensation competitive and retain a high performing management team. In evaluating the updated target bonus opportunities, the Committee also considered the expanded scope of responsibilities with advancing barzolvolimab through multiple late-stage registrational studies and preparing for potential commercialization. Corporate goals are proposed by management, reviewed and approved by the Compensation and Organization Development Committee and also approved by the Board of Directors on an annual basis. The Compensation and Organization Development Committee considers and assigns a relative weight to appropriately focus efforts on corporate goals that are intended to enhance shareholder value.

The Compensation and Organization Development Committee reviewed the 2025 corporate goals at meetings held in April, June and September 2025 to gauge our levels of achievement and to assess whether the corporate goals approved earlier in the year remained relevant and complete. In December 2025 and January 2026, prior to approving 2025 incentive bonuses, the Compensation and Organization Development Committee evaluated our 2025 performance by assessing if, and the extent to which, we achieved or failed to achieve the corporate goals approved by the Board of Directors for 2025. The Compensation and Organization Development Committee considered the 2025 performance and determined that based on the success the Company had in accomplishing the significant milestones detailed above we met 100% of our 2025 corporate goals for pipeline development and business and financial operations. Our corporate goals for 2025 and the level at which the Compensation and Organization Development Committee determined they were achieved are as follows:

#### 2025 Corporate Goals

---

| | | | |
|:---|:---|:---|:---|
|  | **Pipeline Development:**  | **Business and Financial Operations:**  | **Totals:**  |
| Relative <br> Weight  | 65% | 35% | 100%  |
| Goals  | &nbsp;&nbsp;&nbsp; • Progress the barzolvolimab clinical program, including continued execution of ongoing studies, reporting data at key medical meetings and advancing activities to prepare for potential commercialization. <br>• Progress our bispecific clinical and preclinical programs. <br>| &nbsp;&nbsp;&nbsp; • Fund the continued development of our clinical and preclinical programs and the overall operation of our business. <br>• Progress activities that support operational readiness and the potential commercialization of barzolvolimab <br>• Execute across Diversity and Inclusion initiatives. <br>|  |
| <br> **2025** <br> **Achievement**  | 65% | 35% | 100%  |

---

At the Compensation and Organization Development Committee's January 2026 meeting, Mr. Marucci reviewed in detail the performance of each Executive Officer, excluding himself, and considered such individual's contributions to our success

32 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

in 2025. Mr. Marucci's bonus recommendations were based on such individual performance assessments and the fact that the Company achieved 100% of its predetermined corporate goals in 2025 and each employee, including the Executive Officers, contributed to our success in achieving the 2025 corporate goals.

The Compensation and Organization Development Committee discussed Mr. Marucci's recommendations for the Named Executive Officers and reviewed Mr. Marucci's performance for fiscal 2025. Based on Mr. Marucci's recommendations for each of the Named Executive Officers, the Compensation and Organization Development Committee's review of Mr. Marucci's performance and the Compensation and Organization Development Committee's determination that the Company achieved 100% of the corporate goals for 2025, the Compensation and Organization Development Committee approved the following annual bonus payments for our Named Executive Officers:

---

| | | | |
|:---|:---|:---|:---|
| **Name**  | **Target <br> % of Base <br> Salary**  | **Final Payout <br> % of Base <br> Salary**  | **Final <br> Payout <br> $**  |
| Anthony S. Marucci  | ![[MISSING IMAGE: pc_anthonyfinal-pn.jpg]](pc_anthonyfinal-pn.jpg)  | ![[MISSING IMAGE: pc_anthonyfinal-pn.jpg]](pc_anthonyfinal-pn.jpg)  | **$534300**  |
| Tibor Keler, Ph.D.  | ![[MISSING IMAGE: pc_tiborfinal-pn.jpg]](pc_tiborfinal-pn.jpg)  | ![[MISSING IMAGE: pc_tiborfinal-pn.jpg]](pc_tiborfinal-pn.jpg)  | **$304366**  |
| Elizabeth Crowley  | ![[MISSING IMAGE: pc_dianetrgt-pn.jpg]](pc_dianetrgt-pn.jpg)  | ![[MISSING IMAGE: pc_dianefinal-pn.jpg]](pc_dianefinal-pn.jpg)  | **$260000**  |
| Margo Heath-Chiozzi, M.D.  | ![[MISSING IMAGE: pc_margofinal-pn.jpg]](pc_margofinal-pn.jpg)  | ![[MISSING IMAGE: pc_margofinal-pn.jpg]](pc_margofinal-pn.jpg)  | **$225450**  |
| Sam Martin  | ![[MISSING IMAGE: pc_samfinal-pn.jpg]](pc_samfinal-pn.jpg)  | ![[MISSING IMAGE: pc_samfinal-pn.jpg]](pc_samfinal-pn.jpg)  | **$238050**  |

---

The Compensation and Organization Development Committee approved annual bonus payments of 100%, 100%, 116%, 100% and 100% of the 2025 bonus target for Mr. Marucci, Dr. Keler, Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin, respectively, depending on each individual's performance and their respective position. The Compensation and Organization Development Committee determined that annual incentive bonuses paid to the Named Executive Officers for 2025, were fair, reasonable and appropriate based on the factors described above.

*Equity Compensation* 

We also use stock options and equity-based incentive programs to attract, retain, motivate and reward our Executive Officers. Through our equity-based grants, we seek to align the interests of our Executive Officers with our stockholders, reward and motivate both near-term and long-term executive performance and provide an incentive for retention. Our decisions regarding the amount and type of equity incentive compensation and relative weighting of these awards among total executive compensation have been based on our understanding of market practices of similarly situated companies and our negotiations with our executives in connection with their initial employment or promotion.

We have adopted an equity grant policy that formalizes how we grant equity awards by setting a regular schedule for granting equity awards in connection with the hiring or promotion of any of our employees, granting annual equity awards and granting equity awards to non-employee directors. Such policy also outlines grant approval requirements and specifies the vesting schedule and exercise prices for stock option awards. We believe that this policy will mitigate the risk that issues or concerns would be raised in the future regarding the timing of grants of equity awards to our officers, directors and employees.

All such grants to our Named Executive Officers are subject to prior approval by the Compensation and Organization Development Committee at a regularly scheduled meeting during the year. The date of grant and the fair market value of

Celldex Therapeutics \| 33

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

the award are based upon the date of the Compensation and Organization Development Committee meeting approving such grant. When granting equity-based awards, the Compensation and Organization Development Committee considers a number of factors in determining the amount of equity incentive awards, if any, to grant to our executives, including:

• the existing levels of stock ownership among the Executive Officers relative to each other and to our employees as a whole;

• previous grants of stock options to such Executive Officers;

• vesting schedules of previously granted options;

• the performance of the executives and their contributions to our overall performance;

• an outside survey of stock option grants and restricted common stock awards in the biotechnology industry;

• an outside survey of similarly situated biotechnology companies' proxy statements;

• personal knowledge of the Compensation and Organization Development Committee members regarding executive stock options and restricted common stock awards at comparable companies;

• the financial statement impact of stock option awards on our results of operations; and

• the amount and percentage of our total equity on a diluted basis held by our executives.

Equity compensation awards to our Named Executive Officers consist of stock option awards. Stock option awards provide our Executive Officers with the right to purchase shares of our common stock at a fixed exercise price typically for a period of up to ten years, subject to continued employment with us. Stock options are earned on the basis of continued service to us and generally vest over four years, beginning with 25% vesting one year after the date of grant, then pro-rata vesting quarterly thereafter. All historical option grants were made at what our Compensation and Organization Development Committee and Board of Directors determined to be the fair market value of our shares of our common stock on the respective grant dates.

On June 5, 2025, the Compensation and Organization Development Committee awarded stock options to all qualified employees, including the following stock options to our Named Executive Officers:

---

| | | | |
|:---|:---|:---|:---|
| **Name**  | **Number of <br> Options**  | **Exercise Price <br> ($/Sh)<sup>(1)</sup>**  | **Grant Date <br> Fair Value of <br> Option Awards <br> ($)<sup>(2)</sup>**  |
| Anthony S. Marucci | 300000 | 19.53 | 4027590 |
| Tibor Keler, Ph.D. | 93000 | 19.53 | 1248553 |
| Elizabeth Crowley | 85000 | 19.53 | 1141151 |
| Margo Heath-Chiozzi, M.D. | 82000 | 19.53 | 1100875 |
| Sam Martin | 81000 | 19.53 | 1087449 |

---

(1) The exercise prices reflect the closing price of our common stock on the grant date.

(2) The grant date fair values are generally the amount we would expense in our financial statements over the award's service period, but does not include a reduction for estimated forfeitures.

The stock options granted to our Executive Officers in 2025 have exercise prices equal to 100% of the fair value on the date of grant and vest over four years, beginning with 25% vesting one year after the date of grant, then pro-rata vesting quarterly thereafter based on continued service. We believe that stock options structured in this manner encourage our Executive Officers to focus on increasing stockholder value and stock price appreciation over the long term and limit unnecessary risk taking behavior, while promoting retention.

*Other Benefits* 

We believe that establishing competitive benefit packages for our employees is an important factor in attracting and retaining highly qualified personnel. Executive Officers are eligible to participate in all of our employee benefit plans, such as medical, dental, group life and accidental death and dismemberment insurance, short and long-term disability coverage and our 401(k) plan, in each case on the same basis as other employees. We provide a matching contribution under our 401(k) plan. In addition, Mr. Marucci's compensation includes the annual premium for a $1,000,000 term life insurance policy and the personal use of a Company car.

*Employment Agreements and Post-Termination Compensation and Benefits* 

We depend greatly on the intellectual capabilities and experience of our key executives. Our success is dependent on our ability to attract and retain highly skilled executives with significant experience in the biotechnology industry, particularly

34 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

as we expand our activities in clinical trials, the regulatory approval process and sales and manufacturing. Therefore we enter into employment agreements with each of our Named Executive Officers.

In general, each employment arrangement provides for cash severance, 100% acceleration of any unvested options, and/or other equity awards and continuation of certain employee benefits in the event that an executive's employment is terminated within a one year period immediately following a change of control either without cause or by the executive for good reason. The cash severance consists of a single lump sum payment equal to (i) twenty-four (24) times the executive's highest monthly base compensation paid hereunder during the preceding twenty-four month period, plus (ii) 150% (200%, in the case of Mr. Marucci) of the highest one-year annual bonus actually received by the executive during the preceding two full fiscal years prior to the date of termination. We use a "double trigger" with respect to benefits that are to be provided in connection with a change of control. A change of control does not itself trigger benefits; rather, benefits are paid only if the employment of the executive is terminated by us other than for cause, death or disability or by the executive for good reason during the one year period immediately following the change of control. We believe a "double trigger" benefit maximizes shareholder value because it prevents a windfall to executives in the event of a change of control in which the executive retains significant responsibility as defined in his or her individual agreement, while still providing our executives appropriate incentives to cooperate in negotiating any change of control that may put their jobs at risk.

In addition to the benefits that only accrue in connection with a change of control, our agreements with the Named Executive Officers provide for cash severance, 25% acceleration of unvested options (in the case of Mr. Marucci, Dr. Keler and Ms. Crowley) and/or other equity awards and continuation of certain employee benefits if we terminate their employment with us without cause or they terminate their employment with us for good reason, as such terms are defined in the applicable agreement with the Executive Officer. The cash severance consists of a lump sum cash payment equal to 100% (200% in the case of Mr. Marucci) of the executive's then existing base salary. A further discussion of the terms and projected payments under each of these agreements is set forth below under the heading "*Potential Payments upon Termination of Employment or Change in Control."* 

#### Stock Ownership Policy — Employees
In March 2021, our Board adopted a stock ownership policy which requires our Chief Executive Officer and our other Executive Officers (the "Covered Persons") to own shares of our common stock to further align their interests with those of our stockholders. The guidelines require that Covered Persons achieve the following level of stock ownership as a multiple of annual salary when the policy was adopted:

---

| | |
|:---|:---|
| **Level**  | **Minimum Required <br> Level of Stock Ownership**  |
| **CEO**  |  |
| **Other Executive Officers**  |  |

---

For purposes of these calculations, the following shares of our common stock count toward satisfaction of the guidelines: (i) shares held outright by the Covered Person or his or her immediate family members, (ii) shares held indirectly by trusts, family partnerships and other types of entities formed for the benefit of the Covered Person or his or her immediate family members, (iii) the value of vested stock options (valued at 70% of their net value) and restricted stock units and performance stock units, if any (valued at 70% of their fair market value) and (iv) shares held by investment funds, trusts, retirement funds, partnerships, corporations and other types of entities over which the Covered Person has the ability to influence or direct investment decisions. For purposes of these calculations, the base salary amounts are based on the base salaries in effect as of March 2021 or date of hire for new hires.

Covered Persons are required to achieve the relevant ownership threshold on or before January 1, 2026 (the fifth measurement date following the adoption of the plan) or, if a Covered Person is appointed or promoted after March 2021, five measurement dates from his or her respective date of appointment or promotion, and are based on the base salary in effect at the time of such appointment or promotion.

We assess compliance with these stock ownership guidelines on an annual basis. At January 1, 2026, all officers had achieved their required stock ownership except for Ms. Lawver who has until January 2030.

#### Clawback Policy
We have adopted a clawback policy that requires the recovery of certain erroneously paid incentive compensation received by our Section 16 officers on or after October 2, 2023, as required by SEC rules and Nasdaq Listing Standards implemented pursuant to the Dodd-Frank Act. Under our clawback policy, in the event that we are required to prepare an accounting restatement, we will attempt to recover from our current or former executive officers the pre-tax amount of

Celldex Therapeutics \| 35

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

any erroneously awarded incentive compensation as required by such rules and listing standards. For purposes of the clawback policy, incentive compensation means any compensation that is granted, earned or vested based wholly or in part upon the attainment of any measures determined and presented in accordance with the accounting principles used in preparing our financial statements, and any measures that are derived wholly or in part from such measures, as well as stock or share price and total shareholder return. There were no events during fiscal year 2025 that triggered a right to a clawback or recoupment from any of our executive officers pursuant to our clawback policy. You can review our clawback policy by referring to Exhibit 97 to our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 filed with the SEC on February 25, 2026.

36 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Compensation and Organization Development Committee Report \*
Our Compensation and Organization Development Committee has reviewed and discussed the Compensation Discussion and Analysis with management and based on such review and discussion of the Compensation Discussion and Analysis, the Compensation and Organization Development Committee recommended to the Board that the Compensation Discussion and Analysis be included in this proxy statement.

This Compensation and Organization Development Committee Report shall not be deemed to be incorporated by reference into any filing made by the Company under the Securities Act of 1933 or the Exchange Act, notwithstanding any general statement contained in any such filing incorporating this Proxy Statement by reference, except to the extent the Company incorporates such Report by specific reference.

Compensation and Organization Development Committee:

James J. Marino, J.D., Chair

Cheryl L. Cohen

Denice Torres, J.D.

\*

The foregoing report of the Compensation and Organization Development Committee is not to be deemed "filed" with the SEC (irrespective of any general incorporation language in any document filed with the SEC) or subject to Regulation 14A of the Securities Exchange Act of 1934, as amended, or to the liabilities of Section 18 of the Securities Exchange Act of 1934, except to the extent we specifically incorporate it by reference into a document filed with the SEC.

Celldex Therapeutics \| 37

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Summary Compensation Table
The following summary compensation table reflects certain information concerning compensation for services in all capacities awarded to, earned by or paid during the years ended December 31, 2025, 2024 and 2023 to (i) our Chief Executive Officer, (ii) our Chief Financial Officer, and (iii) our three most highly compensated Executive Officers, other than the Chief Executive Officer and Chief Financial Officer, who were serving as Executive Officers as of December 31, 2025 (collectively, the "Named Executive Officers").

---

| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| **Name and Principal <br> Position**  | **Years**  | **Salary <br> ($)**  | **Bonus <br> ($)<sup>(1)</sup>**  | **Stock <br> Awards <br> ($)**  | **Option <br> Awards <br> ($)<sup>(2)</sup>**  | **Non-Equity <br> Incentive <br> Plan <br> Compensation <br> ($)**  | **Change in <br> Pension <br> Value and <br> Nonqualified <br> Deferred <br> Compensation <br> Earnings <br> ($)**  | **All Other <br> Compensation <br> ($)<sup>(3)</sup>**  | **Total <br> ($)**  |
| **Anthony S. Marucci** <br> President and Chief <br> Executive Officer  | 2025 | 785804 | 534300 |  | 4027590 |  |  | 19015 | 5366709 |
| **Anthony S. Marucci** <br> President and Chief <br> Executive Officer  | 2024 | 751766 | 554000 |  | 7903800 |  |  | 19599 | 9229165 |
| **Anthony S. Marucci** <br> President and Chief <br> Executive Officer  | 2023 | 721218 | 530000 |  | 7092975 |  |  | 17651 | 8361844 |
| **Tibor Keler., Ph.D.** <br> Executive Vice President and <br> Chief Scientific Officer  | 2025 | 552699 | 304366 |  | 1248553 |  |  | 10099 | 2115717 |
| **Tibor Keler., Ph.D.** <br> Executive Vice President and <br> Chief Scientific Officer  | 2024 | 530727 | 295000 |  | 2450178 |  |  | 10073 | 3285978 |
| **Tibor Keler., Ph.D.** <br> Executive Vice President and <br> Chief Scientific Officer  | 2023 | 509804 | 291000 |  | 2610215 |  |  | 9590 | 3420609 |
| **Elizabeth Crowley**<sup>(4)</sup> <br> Senior Vice President, <br> Chief Product Development <br> Officer  | 2025 | 473883 | 260000 |  | 1141151 |  |  | 10175 | 1885209 |
| **Elizabeth Crowley**<sup>(4)</sup> <br> Senior Vice President, <br> Chief Product Development <br> Officer  | 2024 | 446905 | 234000 |  | 2239410 |  |  | 10033 | 2930348 |
| **Margo Heath-Chiozzi, M.D.** <br> Senior Vice President, <br> Regulatory Affairs  | 2025 | 483900 | 225450 |  | 1100875 |  |  | 10134 | 1820359 |
| **Margo Heath-Chiozzi, M.D.** <br> Senior Vice President, <br> Regulatory Affairs  | 2024 | 461338 | 228034 |  | 2160372 |  |  | 10080 | 2859824 |
| **Margo Heath-Chiozzi, M.D.** <br> Senior Vice President, <br> Regulatory Affairs  | 2023 | 440259 | 217500 |  | 2269752 |  |  | 9455 | 2936966 |
| **Sam Martin** <br> Senior Vice President <br> and Chief Financial Officer  | 2025 | 490790 | 238050 |  | 1087449 |  |  | 10823 | 1827112 |
| **Sam Martin** <br> Senior Vice President <br> and Chief Financial Officer  | 2024 | 466470 | 229076 |  | 2134026 |  |  | 10548 | 2840120 |
| **Sam Martin** <br> Senior Vice President <br> and Chief Financial Officer  | 2023 | 447771 | 219475 |  | 2269752 |  |  | 9628 | 2946626 |

---

(1) The amounts in the Bonus column include annual bonus amounts earned by each of our Named Executive Officers in 2025, 2024 and 2023.

(2) The amounts in the Option Awards column reflect the dollar amounts for the aggregate grant date fair value in accordance with accounting principles generally accepted in the United States of America (U.S. GAAP) of stock option awards made in fiscal years ended December 31, 2025, 2024 and 2023 for annual awards pursuant to the 2021 Incentive Plan. For a discussion regarding the valuation of our stock option awards for financial statement reporting purposes, please refer to Note 2 in the Notes to the Financial Statements contained in our Annual Report on Form 10-K for the year ended December 31, 2025. These amounts do not represent the actual amounts paid to the Named Executive Officers or the actual value that may be realized by the Named Executive Officers upon exercise of such stock options.

(3) The amounts listed in the All Other Compensation column include our matching contribution to the 401(k) Savings Plan of each Named Executive Officer and premiums paid for life insurance under our nondiscriminatory group plan for each Named Executive Officer. In addition, Mr. Marucci's compensation includes (i) the annual premium of $2,550 in 2025, 2024 and 2023 for a $1,000,000 term life insurance policy and (ii) $3,560, $5,531 and $4,051 for the personal use of a Company car in 2025, 2024 and 2023, respectively.

(4) Ms. Crowley became Senior Vice President and Chief Product Development in August 2016.

38 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Grants of Plan-Based Awards
The following table provides information on stock options and stock awards granted in 2025 to each of our Named Executive Officers.

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| **Name**  | **Grant <br> Date**  | **Estimated Future <br> Payouts Under <br> Equity Incentive Plan Awards**  | **Estimated Future <br> Payouts Under <br> Equity Incentive Plan Awards**  | **Estimated Future <br> Payouts Under <br> Equity Incentive Plan Awards**  | **All Other <br> Stock <br> Awards: <br> Number of <br> Shares of <br> Stock or <br> Units <br> (#)**  | **All Other <br> Option <br> Awards: <br> Number of <br> Securities <br> Underlying <br> Options <br> (#)**  | **Exercise or <br> Base Price of <br> Option <br> Awards <br> ($/Sh)<sup>(1)</sup>**  | **Grant Date <br> Fair Value of <br> Stock and <br> Option <br> Awards <br> ($)<sup>(2)</sup>**  |
| **Name**  | **Grant <br> Date**  | **Threshold <br> (#)**  | **Target <br> (#)**  | **Maximum <br> (#)**  | **All Other <br> Stock <br> Awards: <br> Number of <br> Shares of <br> Stock or <br> Units <br> (#)**  | **All Other <br> Option <br> Awards: <br> Number of <br> Securities <br> Underlying <br> Options <br> (#)**  | **Exercise or <br> Base Price of <br> Option <br> Awards <br> ($/Sh)<sup>(1)</sup>**  | **Grant Date <br> Fair Value of <br> Stock and <br> Option <br> Awards <br> ($)<sup>(2)</sup>**  |
| Anthony S. Marucci | 6/5/25 |  |  |  |  | 300000 | 19.53 | 4027590 |
| Tibor Keler, Ph.D. | 6/5/25 |  |  |  |  | 93000 | 19.53 | 1248553 |
| Elizabeth Crowley | 6/5/25 |  |  |  |  | 85000 | 19.53 | 1141151 |
| Margo Heath-Chiozzi, M.D. | 6/5/25 |  |  |  |  | 82000 | 19.53 | 1100875 |
| Sam Martin | 6/5/25 |  |  |  |  | 81000 | 19.53 | 1087449 |

---

(1) The exercise prices reflect the closing price of our common stock on the grant date.

(2) The grant date fair values are generally the amount we would expense in our financial statements over the award's service period, but does not include a reduction for estimated forfeitures.

#### Outstanding Equity Awards at Fiscal Year-End
The following table sets forth certain information regarding the stock option grants and stock awards to our Named Executive Officers at December 31, 2025.

---

| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Option Awards**  | **Option Awards**  | **Option Awards**  | **Option Awards**  | **Option Awards**  | **Stock Awards**  | **Stock Awards**  | **Stock Awards**  | **Stock Awards**  |
| **Name**  | **Number of <br> Securities <br> Underlying <br> Unexercised <br> Options (#) <br> Exercisable**  | **Number of <br> Securities <br> Underlying <br> Unexercised <br> Options (#) <br> Unexercisable**  | **Equity <br> Incentive <br> Plan <br> Awards: <br> Number of <br> Securities <br> Underlying <br> Unexercised <br> Unearned <br> Options <br> (#)**  | **Option <br> Exercise <br> Price ($)**  | **Option <br> Expiration <br> Date**  | **Number of <br> Shares or <br> Units of <br> Stock <br> That <br> Have Not <br> Vested (#)**  | **Market <br> Value of <br> Shares or <br> Units of <br> Stock <br> That <br> Have Not <br> Vested ($)**  | **Equity <br> Incentive <br> Plan <br> Awards: <br> Number of <br> Unearned <br> Shares, <br> Units or <br> Other <br> Rights <br> That <br> Have Not <br> Vested (#)**  | **Equity <br> Incentive <br> Plan <br> Awards: <br> Market or <br> Payout <br> Value of <br> Unearned <br> Shares, <br> Units or <br> Other <br> Rights <br> That <br> Have Not <br> Vested (#)**  |
| Anthony S. Marucci<sup>(1)</sup> |  | 300000 |  | 19.53 | 6/5/35 |  |  |  |  |
| Anthony S. Marucci<sup>(1)</sup> | 112500 | 187500 |  | 36.43 | 6/13/34 |  |  |  |  |
| Anthony S. Marucci<sup>(1)</sup> | 156250 | 93750 |  | 36.87 | 6/15/33 |  |  |  |  |
| Anthony S. Marucci<sup>(1)</sup> | 218750 | 31250 |  | 22.48 | 6/16/32 |  |  |  |  |
| Anthony S. Marucci | 224000 |  |  | 28.00 | 6/17/31 |  |  |  |  |
| Anthony S. Marucci | 245000 |  |  | 10.38 | 6/18/30 |  |  |  |  |
| Anthony S. Marucci | 25000 |  |  | 2.78 | 6/19/29 |  |  |  |  |
| Anthony S. Marucci | 26665 |  |  | 9.02 | 6/13/28 |  |  |  |  |
| Anthony S. Marucci | 31665 |  |  | 34.80 | 6/15/27 |  |  |  |  |
| Anthony S. Marucci | 31665 |  |  | 70.80 | 6/8/26 |  |  |  |  |
| Tibor Keler, Ph.D.<sup>(1)</sup> |  | 93000 |  | 19.53 | 6/5/35 |  |  |  |  |
| Tibor Keler, Ph.D.<sup>(1)</sup> | 34875 | 58125 |  | 36.43 | 6/13/34 |  |  |  |  |
| Tibor Keler, Ph.D.<sup>(1)</sup> | 57500 | 34500 |  | 36.87 | 6/15/33 |  |  |  |  |
| Tibor Keler, Ph.D.<sup>(1)</sup> | 79625 | 11375 |  | 22.48 | 6/16/32 |  |  |  |  |
| Tibor Keler, Ph.D. | 91000 |  |  | 28.00 | 6/17/31 |  |  |  |  |
| Tibor Keler, Ph.D. | 108000 |  |  | 10.38 | 6/18/30 |  |  |  |  |

---

Celldex Therapeutics \| 39

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

---

| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Option Awards**  | **Option Awards**  | **Option Awards**  | **Option Awards**  | **Option Awards**  | **Stock Awards**  | **Stock Awards**  | **Stock Awards**  | **Stock Awards**  |
| **Name**  | **Number of <br> Securities <br> Underlying <br> UnexercisedOptions (#) <br> Exercisable**  | **Number of <br> Securities <br> Underlying <br> Unexercised <br> Options (#) <br> Unexercisable**  | **Equity <br> Incentive <br> Plan <br> Awards: <br> Number of <br> Securities <br> Underlying <br> UnexercisedUnearned <br> Options <br> (#)**  | **Option <br> ExercisePrice ($)**  | **Option <br> ExpirationDate**  | **Number ofShares or <br> Units of <br> Stock <br> That <br> Have Not <br> Vested (#)**  | **Market <br> Value of <br> Shares or <br> Units of <br> Stock <br> That <br> Have Not <br> Vested ($)**  | **Equity <br> Incentive <br> Plan <br> Awards: <br> Number ofUnearned <br> Shares, <br> Units or <br> Other <br> Rights <br> That <br> Have Not <br> Vested (#)**  | **Equity <br> Incentive <br> Plan <br> Awards: <br> Market or <br> Payout <br> Value of <br> Unearned <br> Shares, <br> Units or <br> Other <br> Rights <br> That <br> Have Not <br> Vested (#)**  |
| Tibor Keler, Ph.D | 43140 |  |  | 2.78 | 6/19/29 |  |  |  |  |
| Tibor Keler, Ph.D. | 25999 |  |  | 9.02 | 6/13/28 |  |  |  |  |
| Tibor Keler, Ph.D. | 10799 |  |  | 34.80 | 6/15/27 |  |  |  |  |
| Tibor Keler, Ph.D. | 10799 |  |  | 70.80 | 6/8/26 |  |  |  |  |
| Elizabeth Crowley<sup>(1)</sup> |  | 85000 |  | 19.53 | 6/5/35 |  |  |  |  |
| Elizabeth Crowley<sup>(1)</sup> | 31875 | 53125 |  | 36.43 | 6/13/34 |  |  |  |  |
| Elizabeth Crowley<sup>(1)</sup> | 50000 | 30000 |  | 36.87 | 6/15/33 |  |  |  |  |
| Elizabeth Crowley<sup>(1)</sup> | 67375 | 9625 |  | 22.48 | 6/16/32 |  |  |  |  |
| Elizabeth Crowley | 58000 |  |  | 28.00 | 6/17/31 |  |  |  |  |
| Elizabeth Crowley | 46500 |  |  | 10.38 | 6/18/30 |  |  |  |  |
| Elizabeth Crowley | 5466 |  |  | 34.80 | 6/15/27 |  |  |  |  |
| Elizabeth Crowley | 5399 |  |  | 70.80 | 6/8/26 |  |  |  |  |
| Margo Heath-Chiozzi, M.D<sup>(1)</sup> |  | 82000 |  | 19.53 | 6/5/35 |  |  |  |  |
| Margo Heath-Chiozzi, M.D<sup>(1)</sup> | 30750 | 51250 |  | 36.43 | 6/13/34 |  |  |  |  |
| Margo Heath-Chiozzi, M.D<sup>(1)</sup> | 50000 | 30000 |  | 36.87 | 6/15/33 |  |  |  |  |
| Margo Heath-Chiozzi, M.D<sup>(1)</sup> | 67375 | 9625 |  | 22.48 | 6/16/32 |  |  |  |  |
| Margo Heath-Chiozzi, M.D | 62500 |  |  | 28.00 | 6/17/31 |  |  |  |  |
| Margo Heath-Chiozzi, M.D | 23023 |  |  | 10.38 | 6/18/30 |  |  |  |  |
| Margo Heath-Chiozzi, M.D | 12732 |  |  | 2.78 | 6/19/29 |  |  |  |  |
| Margo Heath-Chiozzi, M.D | 5000 |  |  | 45.15 | 10/3/27 |  |  |  |  |
| Sam Martin<sup>(1)</sup> |  | 81000 |  | 19.53 | 6/5/35 |  |  |  |  |
| Sam Martin<sup>(1)</sup> | 30375 | 50625 |  | 36.43 | 6/13/34 |  |  |  |  |
| Sam Martin<sup>(1)</sup> | 50000 | 30000 |  | 36.87 | 6/15/33 |  |  |  |  |
| Sam Martin<sup>(1)</sup> | 74375 | 10625 |  | 22.48 | 6/16/32 |  |  |  |  |
| Sam Martin | 85000 |  |  | 28.00 | 6/17/31 |  |  |  |  |
| Sam Martin | 63632 |  |  | 10.38 | 6/18/30 |  |  |  |  |
| Sam Martin | 4332 |  |  | 34.80 | 6/15/27 |  |  |  |  |
| Sam Martin | 1399 |  |  | 70.80 | 6/8/26 |  |  |  |  |

---

(1) 25% of the options vest on the first anniversary of the grant date and the remainder vest quarterly (in equal amounts) over the subsequent 12 quarters.

40 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Option Exercises and Stock Vested
The following table sets forth certain information regarding the number of option exercises in fiscal 2025 and the number of shares of stock issued under the 2021 Incentive Plan and 2008 Plan that vested in fiscal 2025 and the corresponding amounts realized by our Named Executive Officers.

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Option Awards**  | **Option Awards**  | **Stock Awards**  | **Stock Awards**  |
| **Name**  | **Number of Shares <br> Acquired on Exercise <br> (#)**  | **Value Realized <br> on Exercise <br> ($)<sup>(1)</sup>**  | **Number of Shares <br> Acquired on Vesting <br> (#)**  | **Value Realized <br> on Vesting <br> ($)**  |
| Anthony S. Marucci |  |  |  |  |
| Tibor Keler, Ph.D. |  |  |  |  |
| Elizabeth Crowley |  |  |  |  |
| Margo Heath-Chiozzi, M.D. |  |  |  |  |
| Sam Martin |  |  |  |  |

---

(1) Value realized on exercise represents difference between sale price and exercise price for shares sold or difference between closing price on day of exercise and exercise price for shares held and not sold.

#### Employment Agreements
The terms and conditions of the employment agreements of Mr. Marucci, Dr. Keler, Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin are governed by written employment contracts which became effective on December 8, 2025. The employment agreements provide, among other things, for:

• current annual base salary ($822,000 in the case of Mr. Marucci, $574,276 in the case of Dr. Keler, $498,000 in the case of Ms. Crowley, $501,000 in the case of Dr. Heath-Chiozzi and $529,000 in the case of Mr. Martin) or such greater amount as may from time to time be determined by the Board of Directors or the Compensation and Organization Development Committee thereof;

• eligibility for an annual bonus with a current bonus target (65% of base salary in the case of Mr. Marucci, 53% of base salary in the case of Dr. Keler and 45% of base salary in the case of Ms. Crowley, Dr. Heath-Chiozzi and Mr. Martin);

• a lump sum severance payment equal to 100% (200% in the case of Mr. Marucci only) of the executive's then-existing annual base salary in the event that the executive's employment is terminated without cause or the executive resigns "for good reason" (as defined in the employment agreement) and 25% accelerated vesting of any unvested equity awards (in the case of Mr. Marucci, Dr. Keler and Ms. Crowley); and

• accelerated vesting of any unvested equity awards (as defined in the employment agreement) and a lump sum cash payment equal to twenty-four (24) times the executive's highest monthly base compensation (not including bonus) during the twenty-four month period preceding the date of termination plus 150% (200% in the case of Mr. Marucci only) of the highest one-year annual bonus actually received by the executive during the two full fiscal years preceding the date of termination in the event of termination without cause or resignation "for good reason" by the executive within one year immediately following a change in control (as defined in the employment agreement).

Payment of cash severance and certain supplemental benefits is conditioned upon the executive executing and delivering to us a release within 55 days of termination of employment. The employment arrangements are also conditioned upon each executive entering into an employee non-disclosure invention assignment agreement which includes confidentiality, assignment of inventions, non-competition, non-solicitation and non-disparagement restrictions. The assignment of inventions provision applies to inventions created while employed. The confidentiality and non-disparagement provisions apply during and after employment. The non-competition and non-solicitation provisions apply during employment and for 12 months thereafter, except do not apply in case of a termination without cause or for good reason within one year following a change in control. Waiver of a breach by the executive of the employee non-disclosure invention assignment agreement would require our written agreement.

The employment agreements had an initial term through December 31, 2026 and shall automatically renew for additional one year terms unless either party gives ninety (90) days prior written notice of its intent not to renew. The Company may terminate the employment agreements without cause, on 90-days' prior notice, or for cause, subject to a 30-day cure period in certain circumstances.

#### Pension Benefits
None of our Named Executive Officers participate in qualified or nonqualified defined benefit plans sponsored by us.

Celldex Therapeutics \| 41

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Nonqualified Deferred Compensation
None of our Named Executive Officers are covered by a defined contribution or other plan that provides for the deferral of compensation on a basis that is not tax-qualified.

#### Potential Payments Upon Termination of Employment or Change in Control
Our Named Executive Officers have provisions in their employment agreements regarding severance upon certain termination events or acceleration of stock options in the event of our change of control or termination following a change of control. These severance and acceleration provisions are described in "Employment Agreements," and certain estimates of these change of control benefits are provided in the tables below.

Payment of cash severance and certain supplemental benefits is conditioned upon the Named Executive Officer executing and delivering to us a release within 55 days of termination of employment. The employment arrangements are also conditioned upon each Named Executive Officer entering into an employee non-disclosure invention assignment agreement which includes confidentiality, assignment of inventions, non-competition, non-solicitation and non-disparagement restrictions. The assignment of inventions provision applies to inventions created while employed. The confidentiality and non-disparagement provisions apply during and after employment. The non-competition and non-solicitation provisions apply during employment and for 12 months thereafter, except do not apply in case of a termination without cause or for good reason within one year following a change in control. Waiver of a breach by the executive of the employee non-disclosure invention assignment agreement would require our written agreement.

The following table describes the potential payments and benefits upon employment termination for our Named Executive Officers as if their employment had terminated as of December 31, 2025.

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **Executive benefits and payments <br> upon termination**  | **Voluntary <br> resignation <br> for no good <br> reason**  | **Voluntary <br> resignation <br> for good <br> reason<sup>(1)</sup>**  | **Termination <br> by Celldex <br> without <br> cause<sup>(1)</sup>**  | **Termination <br> by Celldex <br> for cause**  | **Voluntary termination <br> by the executive <br> for good reason <br> or termination by <br> Celldex without <br> cause in connection <br> with or following <br> change of control<sup>(2)</sup>**  |
| **<u>Anthony S. Marucci</u>**  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Base Salary  | $— | $1644000 | $1644000 | $— | $1644000 |
| &nbsp;&nbsp;&nbsp; Bonus  |  |  |  |  | 1108000 |
| &nbsp;&nbsp;&nbsp; Equity Awards Acceleration<sup>(3)</sup>  |  | 608813 | 608813 |  | 2435250 |
| &nbsp;&nbsp;&nbsp; Continuation of Health Benefits  |  | 62406 | 62406 |  | 62406 |
| &nbsp;&nbsp;&nbsp; Total  | $— | $2315219 | $2315219 | $— | $5249656 |
| **<u>Tibor Keler, Ph.D.</u>**  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Base Salary  | $— | $574276 | $574276 | $— | $1148552 |
| &nbsp;&nbsp;&nbsp; Bonus  |  |  |  |  | 456549 |
| &nbsp;&nbsp;&nbsp; Equity Awards Acceleration<sup>(3)</sup>  |  | 190707 | 190707 |  | 762825 |
| &nbsp;&nbsp;&nbsp; Continuation of Health Benefits  |  | 45648 | 45648 |  | 45648 |
| &nbsp;&nbsp;&nbsp; Total  | $— | $810631 | $810631 | $— | $2413574 |
| **<u>Elizabeth Crowley</u>**  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Base Salary  | $— | $498000 | $498000 | $— | $996000 |
| &nbsp;&nbsp;&nbsp; Bonus  |  |  |  |  | 390000 |
| &nbsp;&nbsp;&nbsp; Equity Awards Acceleration<sup>(3)</sup>  |  | 173399 | 173399 |  | 693595 |
| &nbsp;&nbsp;&nbsp; Continuation of Health Benefits  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Total  | $— | $671399 | $671399 | $— | $2079595 |
| **<u>Margo Heath-Chiozzi, M.D</u>**  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Base Salary  | $— | $501000 | $501000 | $— | $1002000 |
| &nbsp;&nbsp;&nbsp; Bonus  |  |  |  |  | 342051 |
| &nbsp;&nbsp;&nbsp; Equity Awards Acceleration<sup>(3)</sup>  |  |  |  |  | 670705 |
| &nbsp;&nbsp;&nbsp; Continuation of Health Benefits  |  | 45648 | 45648 |  | 45648 |
| &nbsp;&nbsp;&nbsp; Total  | $— | $546648 | $546648 | $— | $2060404 |
| **<u>Sam Martin</u>**  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Base Salary  | $— | $529000 | $529000 | $— | $1058000 |
| &nbsp;&nbsp;&nbsp; Bonus  |  |  |  |  | 357075 |
| &nbsp;&nbsp;&nbsp; Equity Awards Acceleration<sup>(3)</sup>  |  |  |  |  | 667755 |
| &nbsp;&nbsp;&nbsp; Continuation of Health Benefits  |  | 62406 | 62406 |  | 62406 |
| &nbsp;&nbsp;&nbsp; Total  | $— | $591406 | $591406 | $— | $2145236 |

---

42 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

(1) Upon termination without cause or resignation for good reason, the employee is generally entitled to a lump sum payment equal to 100% (200% in the case of Mr. Marucci only) of the employee's then annual base salary, continuation of certain employee benefits and 25% accelerated vesting of any unvested equity awards (in the case of Mr. Marucci, Dr. Keler and Ms. Crowley).

(2) The employee is generally entitled to accelerated vesting of any unvested equity awards (as defined in the employment agreement) and a lump sum cash payment equal to twenty-four (24) times the executive's highest monthly base compensation (not including bonus) during the twenty-four month period preceding the date of termination plus 150% (200% in the case of Mr. Marucci only) of the highest one-year annual bonus actually received by the executive during the two full fiscal years preceding the date of termination in the event of termination without cause or resignation "for good reason" by the executive within one year immediately following a change in control (as defined in the employment agreement) and continuation of certain employee benefits.

(3) The exercise price of each unvested option outstanding was greater than $27.16 per share (the closing price on the last trading day of our 2025 fiscal year).

#### Securities Authorized For Issuance Under Equity Compensation Plans
The following table provides information as of December 31, 2025 regarding shares of our common stock that may be issued under our existing equity compensation plans, including our 2021 Incentive Plan, our 2008 Plan and our 2004 Plan.

---

| | | | |
|:---|:---|:---|:---|
| **Plan Category**  | **(a) <br> Number of securities to be <br> issued upon exercise of <br> outstanding options and <br> rights<sup>(1)</sup>**  | **(b) <br> Weighted-average exercise <br> price of outstanding <br> options and rights**  | **(c) <br> Number of securities <br> remaining available for <br> future issuance under equity <br> compensation plans <br> (excluding securities <br> reflected in column (a))**  |
| Equity compensation plans approved by security holders<sup>(2)</sup>  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;9134278<sup>(3</sup>) | $26.49 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2753587<sup>(4</sup>) |

---

(1) Does not include any Restricted Stock as such shares are already reflected in our outstanding shares.

(2) Consists of the 2021 Incentive Plan, 2008 Plan and the 2004 Plan.

(3) Does not include purchase rights accruing under the 2004 Plan because the purchase price (and therefore the number of shares to be purchased) will not be determined until the end of the purchase period.

(4) Includes shares available for future issuance under the 2021 Incentive Plan and the 2004 Plan as of December 31, 2025, of which 2,624,836 shares are available for grants in the form of restricted stock, deferred stock, performance shares or unrestricted stock under the 2021 Incentive Plan.

#### CEO Pay Ratio
As required by Section 953(b) of the Dodd-Frank Wall Street Reform and Consumer Protection Act and Item 402(u) of Regulation S-K, we are required to disclose the ratio of our median employee's annual total compensation to the annual total compensation of our principal Executive Officer.

The purpose of this disclosure is to provide a measure of the equitability of pay within our company. We believe our compensation philosophy and process yield an equitable result for all of our employees. During fiscal 2025, the principal Executive Officer of Celldex was our Chief Executive Officer, Anthony S. Marucci. For 2025, the annual total compensation, using the same methodology we use for our Named Executive Officers as set forth in the summary compensation table, for Mr. Marucci was $5,366,709, and for our median employee was $235,733, resulting in an estimated pay ratio of 23 to 1.

In accordance with Item 402(u) of Regulation S-K, we identified the median employee by (i) determining our employee population as of December 31, 2024 (including all full-time, part-time, salaried, hourly, and seasonal employees, but excluding Mr. Marucci), (ii) calculating the total compensation for each employee for fiscal 2024 by aggregating (A) annual base salary for salaried employees (or hourly rate multiplied by expected annual work schedule, for hourly employees), (B) the bonus for 2024, and (C) the estimated accounting value of any equity awards granted during 2024, and (iii) ranking this compensation measure for our employees from lowest to highest. We do not believe that there has been any change in our employee population or employee compensation arrangements for fiscal 2025 that would result in a significant change to our pay ratio disclosure. As such, and as permitted by Item 402(u) of Regulation S-K, we are using the same median employee for our pay ratio disclosure that we identified for our pay ratio disclosure for fiscal 2024.

The pay ratio reported above is a reasonable estimate calculated in a manner consistent with SEC rules based on our internal records and the methodology described above. Because the SEC rules for identifying the median compensated employee and calculating the pay ratio based on that employee's annual total compensation allow companies to adopt a variety of methodologies, to apply certain exclusions, and to make reasonable estimates and assumptions that reflect their employee populations and compensation practices, the pay ratio reported by other companies may not be comparable to the pay ratio reported above, as other companies have different employee populations and compensation practices and may utilize different methodologies, exclusions, estimates and assumptions in calculating their own pay ratios.

Celldex Therapeutics \| 43

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Pay Versus Performance Table
In accordance with rules adopted by the SEC pursuant to the Dodd-Frank Act, below is disclosure regarding executive compensation for our principal Executive Officer ("PEO," also known as our CEO), and other NEOs and company financial performance for the fiscal years listed below. The Compensation Committee did not consider the pay versus performance disclosure below in making its pay decisions for any of the years shown. Pursuant to SEC rules, the information in this "*Pay Versus Performance*" section shall not be deemed to be incorporated by reference into any Celldex filing under the Securities Act or Exchange Act, unless expressly incorporated by specific reference in such filing.

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| **(a)**  | **(b)**  | **(c)**  | **(d)**  | **(e)**  | **(f)**  | **(g)**  | **(h)**  | **(i)**  |
| **Fiscal year <br> ended <br> December 31,**  | **Summary <br> Compensation <br> Table Total <br> for PEO**  | **Compensation <br> Actually <br> Paid to PEO<sup>(2)</sup>**  | **Average <br> Summary <br> Compensation <br> Table Total for <br> Non-PEO <br> NEOs<sup>(1)</sup>**  | **Average <br> Compensation <br> Actually <br> Paid to <br> Non-PEO <br> NEOs<sup>(2)</sup>**  | **Value of <br> Initial <br> Fixed $100 <br> Investment <br> Based <br> on Total <br> Shareholder <br> Return**  | **Value of <br> Initial <br> Fixed $100 <br> Investment <br> Based on <br> Peer Group <br> Total <br> Shareholder <br> Return<sup>(3)</sup>**  | **Net Loss (in <br> thousands)**  | **Year-end <br> cash & <br> investment <br> balance (in <br> thousands)<sup>(4)</sup>**  |
| 2025 | $5366709 | $4834841 | $1912099 | $1728087 | $155 | $201 | $(258757) | $518573 |
| 2024 | $9229165 | $75804 | $2979068 | $98029 | $144 | $156 | $(157863) | $725281 |
| 2023 | $8361844 | $3737921 | $3067602 | $1456996 | $226 | $144 | $(141429) | $423598 |
| 2022 | $5401283 | $10096324 | $2055757 | $3596459 | $254 | $139 | $(112325) | $304952 |
| 2021 | $6045894 | $13902770 | $2390179 | $5115872 | $221 | $124 | $(70511) | $408250 |

---

(1) As reflected elsewhere herein, our Non-PEO NEOs for 2025 and 2024 were Tibor Keler, Ph.D., Sam Martin, Margo-Heath Chiozzi, M.D. and Elizabeth Crowley. Our Non-PEO NEOs for 2023 and 2022 were Tibor Keler, Ph.D., Sam Martin, Margo-Heath Chiozzi, M.D. and Diane C. Young, M.D. Our Non-PEO NEOs for 2021 were Tibor Keler, Ph.D., Freddy Jimenez, Sam Martin and Diane C. Young, M.D.

(2) The following table outlines the adjustments made to the compensation earned by the Company's PEO and other NEOs, as presented in the Summary Compensation Table, to derive the compensation actually paid to the Company's PEO and other NEOs.

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| | **Adjustments**  | **Adjustments**  | **Adjustments**  | **Adjustments**  | **Adjustments**  | **Adjustments**  |
| **PEO**  | **Summary <br> Compensation <br> Table Total**  | **Less: Grant <br> Date Fair Value <br> of Option <br> Awards <br> Granted during <br> the Fiscal <br> Year<sup>(a)</sup>**  | **Add: Year-End <br> Fair Value of <br> Outstanding <br> and Unvested <br> Option Awards <br> Granted during <br> the Fiscal Year<sup>(b)</sup>**  | **Adjust for <br> Change in Fair <br> Value of <br> Outstanding and <br> Unvested Option <br> Awards Granted <br> in Prior Fiscal <br> Years<sup>(b)</sup>**  | **Adjust for Change <br> in Fair Value of <br> Option Awards <br> Granted in Prior <br> Fiscal Years that <br> Vested During the <br> Fiscal Year<sup>(b)</sup>**  | **Compensation <br> Actually Paid**  |
| 2025 | $5366709 | (4027590) | 5348700 | (803438) | (1049540) | $4834841 |
| 2024 | $9229165 | (7903800) | 4626300 | (4593339) | (1282522) | $75804 |
| 2023 | $8361844 | (7092975) | 7152250 | (2343805) | (2339393) | $3737921 |
| 2022 | $5401283 | (4262250) | 9362250 | 1051936 | (1456895) | $10096324 |
| 2021 | $6045894 | (4868797) | 6697600 | 3863005 | 2165068 | $13902770 |
| **Average Non-PEO NEOs**  | **Average Non-PEO NEOs**  |  |  |  |  |  |
| 2025 | $1912099 | (1144507) | 1519922 | (237224) | (322203) | $1728087 |
| 2024 | $2979068 | (2245997) | 1314640 | (1521453) | (428229) | $98029 |
| 2023 | $3067602 | (2354868) | 2374547 | (796800) | (833485) | $1456996 |
| 2022 | $2055757 | (1402280) | 3080180 | 394595 | (531793) | $3596459 |
| 2021 | $2390179 | (1744290) | 2399475 | 1365289 | 705219 | $5115872 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (a)

Amounts reflect the aggregate grant-date fair value reported in the "Option Awards" column in the Summary Compensation Table for the applicable year.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; (b)

Fair values as of each measurement date were determined using valuation assumptions and methodologies in accordance with Accounting Standards Codification (ASC) Topic 718.

(3) The Peer Group TSR set forth in this table utilizes the NASDAQ Pharmaceutical (Subsector) Index (assuming reinvestment of all dividends), which we also utilize in the stock performance graph required by Item 201(e) of Regulation S-K, included in our Annual Report on Form 10-K for the year ended December 31, 2025. The comparison assumes $100 was invested for the period starting December 31, 2020, through the end of the listed year in our company and in the NASDAQ Pharmaceutical (Subsector) Index, respectively, and assumes reinvestment of all dividends. Historical stock performance is not indicative of future stock performance.

(4) Our Company Selected Measure is calculated as follows: Year-end cash and investment balance (in thousands), which is calculated by adding the cash, cash equivalents and marketable securities from our consolidated balance sheet. Identifying a Company Selected Measure is a matter of opinion. Other companies, including our peer companies, may utilize different measures as a basis for compensation or may utilize similar measures that are calculated in a manner that is different from the manner in which we calculate that measure. We may change the Company Selected Measure from year to year, depending upon a number of factors relating to our business.

44 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Relationship between Compensation Actually Paid and TSR
The graph below illustrates the relationship between compensation actually paid to the Company's PEO and other NEOs, our total shareholder return and that of the NASDAQ Pharmaceutical (Subsector) Index.

![[MISSING IMAGE: bc_paidvstsr-pn.jpg]](bc_paidvstsr-pn.jpg)

#### Relationship between Compensation Actually Paid and Net Loss
The graph below illustrates the relationship between compensation actually paid to the Company's PEO and other NEOs and the Company's net loss.

![[MISSING IMAGE: bc_paidvsnetloss-pn.jpg]](bc_paidvsnetloss-pn.jpg)

Celldex Therapeutics \| 45

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Relationship between Compensation Actually Paid and Year-End Cash & Investment Balance
The graph below illustrates the relationship between compensation actually paid to the Company's PEO and other NEOs and the Company's year-end cash and investment balance.

![[MISSING IMAGE: bc_paidvsyearendcash-pn.jpg]](bc_paidvsyearendcash-pn.jpg)

#### Tabular List
The following table sets forth the sole financial performance measure we used to determine the compensation paid to our PEO and other NEOs.

<u> Year-end cash and investment balance </u>

#### Policies and Practices Related to the Grant of Certain Equity Awards Close in Time to the Release of Material Nonpublic Information
We have an Equity Award Grant Policy pursuant to which we may grant equity awards, including stock options, to our employees, including the named executive officers, and our non-employee directors. It is our policy that we shall not backdate any equity grant, or manipulate the timing of the public release of material information or of any equity award with the intent of benefiting a grantee under an equity award. We generally grant stock options only on a regularly scheduled basis. Pursuant to our Equity Award Grant Policy, we grant new-hire equity awards, which may include stock options, as of the date of the new hire's employment start date or date of promotion. In addition, we make annual equity awards, which have historically been in the form of stock options, to our employees, including our named executive officers, on an annual basis on the date of our annual meeting of stockholders. Our non-employee directors receive grants of initial and annual stock option awards, at the time of a director's initial appointment or election to the board and at the time of each annual meeting of our stockholders, respectively, regardless of whether or not we then have material non-public information ("MNPI"), as further described under the heading "Director Compensation" below. We have not timed the release of MNPI for the purpose of affecting the value of executive compensation.

46 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

The following table sets forth information relating to the grant of stock options close in time to the filing of certain SEC reports.

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **Name**  | **Grant date**  | **Number of <br> securities <br> underlying <br> the award**  | **Exercise price <br> of the award <br> ($/Sh)**  | **Grant date <br> fair value of <br> the award<sup>(1)</sup>**  | **Percentage change in the closing <br> market price of the securities <br> underlying the award between the <br> trading day ending immediately prior to <br> the disclosure of material nonpublic <br> information and the trading day <br> beginning immediately following the <br> disclosure of material nonpublic <br> information<sup>(2)</sup>**  |
| **(a)**  | **(b)**  | **(c)**  | **(d)**  | **(e)**  | **(f)**  |
| Anthony S. Marucci | 6/5/2025 | 300000 | $19.53 | $13.43 | 6.0% increase  |
| Tibor Keler, Ph.D. | 6/5/2025 | 93000 | $19.53 | $13.43 | 6.0% increase  |
| Elizabeth Crowley | 6/5/2025 | 85000 | $19.53 | $13.43 | 6.0% increase  |
| Margo Heath-Chiozzi, M.D | 6/5/2025 | 82000 | $19.53 | $13.43 | 6.0% increase  |
| Sam Martin | 6/5/2025 | 81000 | $19.53 | $13.43 | 6.0% increase  |

---

(1) Amounts reflect the grant date fair value of each option award granted, calculated in accordance with ASC 718.

(2) Percentage change in the closing market price of the securities underlying the award between the trading day ending immediately prior to the filing of the Company's Current Report on Form 8-K announcing the results of the 2025 Annual Meeting (the "Annual Meeting 8-K") and the trading day beginning immediately following the date of the filing of the Annual Meeting 8-K.

#### Director Compensation
Effective June 2024, Directors who are not our employees are each entitled to receive a retainer fee of $48,000 each fiscal year ("Annual Retainer"). The Chair of the Board is entitled to receive an annual retainer fee of $35,000 in addition to his or her Annual Retainer and any retainer for committee service. The Chairperson of the Audit Committee, Compensation and Organization Development Committee, Nominating and Corporate Governance Committee and Science and Commercialization Committee of the Board of Directors is entitled to receive an annual retainer fee of $20,000, $15,000, $10,000 and $10,000, respectively, in addition to his or her Annual Retainer. Each committee member of the Audit Committee, Compensation and Organization Development Committee, Nominating and Corporate Governance Committee and Science and Commercialization Committee (other than the Chairperson of a committee) will receive an annual retainer of $10,000, $7,500, $5,000 and $5,000, respectively, in addition to his or her Annual Retainer. Stipends and retainers are paid in advance on a quarterly basis. The Directors shall be reimbursed for necessary travel and business expenses as incurred but will not receive any additional fees for attending meetings or calls of the Board of Directors.

Effective June 2024, Directors who are not our employees are each entitled to receive the lesser of 16,500 options or the number of options subject to the existing Director annual compensation limit of $750,000 and, for new directors, the lesser of 33,000 options or the number of options subject to the existing Director compensation limit of $1,200,000. In June 2025, all non-employee directors received an annual stock option grant to purchase 16,500 shares of the Company's common stock following the 2025 Annual Meeting of Stockholders, except Ms. Torres who received a stock option grant to purchase 33,000 shares.

The following table summarizes the annual compensation for our non-employee directors during 2025.

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| **Name**  | **Fees <br> Earned or <br> Paid in Cash <br> ($)**  | **Stock <br> Awards <br> ($)**  | **Option <br> Awards <br> ($)<sup>(1)</sup>**  | **Non-Equity <br> Incentive Plan <br> Compensation <br> ($)**  | **Change in <br> Pension <br> Value and <br> Nonqualified <br> Deferred <br> Compensation <br> Earnings**  | **All Other <br> Compensation <br> ($)**  | **Total <br> ($)**  |
| Harry H. Penner, Jr. | 75422 |  | 221517 |  |  |  | 296939 |
| Keith L. Brownlie | 67922 |  | 221517 |  |  |  | 289439 |
| Cheryl L. Cohen | 60431 |  | 221517 |  |  |  | 281948 |
| Herbert J. Conrad | 57934 |  | 221517 |  |  |  | 279451 |
| Rita I. Jain, M.D. | 57934 |  | 221517 |  |  |  | 279451 |
| James J. Marino | 72917 |  | 221517 |  |  |  | 294434 |
| Garry A. Neil, M.D. | 62928 |  | 221517 |  |  |  | 284445 |
| Denice Torres | 37416 |  | 443035 |  |  |  | 480451 |

---

Celldex Therapeutics \| 47

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

(1) The amounts in the Option Awards column reflect the grant date fair value in accordance with U.S. GAAP of stock option awards made in 2025 to each of our non-employee directors for awards pursuant to the 2021 Incentive Plan subject to a vesting schedule whereby an equal number of the shares of common stock shall become vested and no longer be subject to risk of forfeiture (so long as the director remains a member of the Board as of such date). As of December 31, 2025, our non-employee directors had the following stock options outstanding: Harry H. Penner, Jr. — 91,866, Keith L. Brownlie — 91,399, Cheryl L. Cohen — 71,500, Herbert J. Conrad — 91,866, Rita, I. Jain, M.D. — 50,100, James J. Marino — 91,399, Garry A. Neil, M.D. — 71,500, and Denice Torres — 33,000. For a discussion regarding the valuation of our stock option awards for financial statement reporting purposes, please refer to Note 2 in the Notes to the Financial Statements contained in our Annual Report on Form 10-K for the year ended December 31, 2025. These amounts do not represent the actual amounts paid to the directors or the actual value that may be realized by the directors upon exercise of such stock options.

#### Compensation and Organization Development Committee Interlocks and Insider Participation
The Compensation and Organization Development Committee of the Board of Directors is currently composed of the following three non-employee directors: James J. Marino, Chair, Cheryl L. Cohen and Denice Torres. None of these Compensation and Organization Development Committee members was an officer or employee of us during the year. No Compensation and Organization Development Committee interlocks between us and another entity existed.

#### Risk Considerations
We do not believe that our compensation practices and policies for our employees, including our Executive Officers, create risks or are likely to create risks that are reasonably likely to have a material adverse effect on our results of operations or financial condition. The Compensation and Organization Development Committee considered our strategic goals and operational practices and evaluated our incentive program design to assess whether these programs foster a business environment that might drive inappropriate decision-making or behavior. We are a biopharmaceutical company that is generating a pipeline of drug candidates to treat diseases for which available treatments are inadequate and do not yet generate earnings. While a significant portion of our executives' compensation is performance-based, we believe several features of our program mitigate inappropriate or excessive risk-taking that could harm shareholder value: we set performance goals that we believe are reasonable and set targets with payouts at multiple levels of performance, rather than an "all or nothing" approach. As discussed above in our Compensation Discussion and Analysis section, we use a mix of performance goals in our annual and long-term incentive programs to align incentive compensation with a broad set of measures important to the creation of shareholder value.

#### Stock Ownership Policy — Non-Employee Directors
In March 2021, our Board adopted stock ownership guidelines applicable to our non-employee directors based on its belief that stock ownership would further align their interests with the long-term interests of our stockholders. The minimum stock ownership requirement for non-employee directors is three times the Annual Retainer. Non-employee directors are required to achieve this level of stock ownership by January 1, 2026 (the fifth measurement date following the adoption of the plan), and any non-employee directors appointed or elected after March 2021 are required to achieve this level of stock ownership by the fifth measurement date from his or her respective date of appointment or election. Measurement dates are January 1 of each year. We assess compliance with these stock ownership guidelines on an annual basis. At January 1, 2026, Mr. Penner, Mr. Conrad and Mr. Marino, were the only non-employee director who had achieved their required stock ownership. Mr. Brownlie was not in compliance as of January 1, 2026 but, as of the date of this proxy statement, he has maintained compliance with the stock ownership guidelines. Ms. Cohen and Dr. Neil have until January 2027, Dr. Jain has until January 2028, and Ms. Torres has until January 2030.

48 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Report of The Audit Committee \*
The undersigned members of the Audit Committee of the Board of Directors of Celldex submit this report in connection with the committee's review of the financial reports for the fiscal year ended December 31, 2025 as follows:

1. The Audit Committee has reviewed and discussed with management the audited financial statements for Celldex for the fiscal year ended December 31, 2025.

2. The Audit Committee has discussed with representatives of PricewaterhouseCoopers LLP the matters which are required to be discussed by applicable requirements of the Public Company Accounting Oversight Board ("PCAOB") and the SEC. That Auditing Standard requires the auditors to ensure that the Audit Committee received information regarding the scope and results of the audit.

3. The Audit Committee has discussed with PricewaterhouseCoopers LLP, the independent registered public accounting firm, the auditors' independence from management and Celldex including the matters in the written disclosures and the letter from the independent auditors required by PCAOB Rule 3526.

In addition, the Audit Committee considered whether the provision of tax or other non-audit services by PricewaterhouseCoopers LLP is compatible with maintaining its independence. In reliance on the reviews and discussions referred to above, the Audit Committee recommended to the Board of Directors (and the Board of Directors has approved) that the audited financial statements be included in Celldex's Annual Report on Form 10-K for the fiscal year ended December 31, 2025 for filing with the Securities and Exchange Commission.

Audit Committee:

Keith L. Brownlie, Chair

James J. Marino, J.D.

Garry Neil, M.D.

\*

The foregoing report of the Audit Committee is not to be deemed "soliciting material" or deemed to be "filed" with the Securities and Exchange Commission (irrespective of any general incorporation language in any document filed with the Securities and Exchange Commission) or subject to Regulation 14A of the Securities Exchange Act of 1934, as amended, or to the liabilities of Section 18 of the Securities Exchange Act of 1934, except to the extent we specifically incorporate it by reference into a document filed with the Securities and Exchange Commission.

Celldex Therapeutics \| 49

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Security Ownership of Certain Beneficial Owners and Management
The following table sets forth certain information as of April 10, 2026 with respect to the beneficial ownership of common stock of the Company by the following: (i) each of the Company's current directors; (ii) each of the Named Executive Officers; (iii) the current Executive Officers; (iv) all of the Executive Officers and directors as a group; and (v) each person known by the Company to own beneficially more than five percent (5%) of the outstanding shares of the Company's common stock.

For purposes of the following table, beneficial ownership is determined in accordance with the applicable SEC rules and the information is not necessarily indicative of beneficial ownership for any other purpose. Except as otherwise noted in the footnotes to the table, we believe that each person or entity named in the table has sole voting and investment power with respect to all shares of the Company's common stock shown as beneficially owned by that person or entity (or shares such power with his or her spouse). Under the SEC's rules, shares of the Company's common stock issuable under options that are exercisable on or within 60 days after April 10, 2026 ("Presently Exercisable Options") are deemed outstanding and therefore included in the number of shares reported as beneficially owned by a person or entity named in the table and are used to compute the percentage of the common stock beneficially owned by that person or entity. These shares are not, however, deemed outstanding for computing the percentage of the common stock beneficially owned by any other person or entity.

The percentage of the common stock beneficially owned by each person or entity named in the following table is based on 78,488,660 shares of common stock outstanding as of April 10, 2026 plus any shares issuable upon exercise of Presently Exercisable Options held by such person or entity.

---

| | | |
|:---|:---|:---|
| **Name and Business Address of Beneficial Owners\***  | **Amount and Nature of <br> Beneficial Ownership<sup>(1)</sup>**  | **Percentage of <br> Common Stock<sup>(2)</sup>**  |
| *5% Holders* |  |  |
|  Wellington Management Group LLP <br> 280 Congress Street <br> Boston, Massachusetts 02210  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;8079608<sup>(3</sup>) | 10.3% |
|  Kynam Capital Management, LP <br> 221 Elm Road <br> Princeton, NJ 08540  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;6500000<sup>(4</sup>) | 8.3% |
|  FMR LLC <br> 245 Summer Street <br> Boston, Massachusetts 02210  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4857668<sup>(5</sup>) | 6.2% |
|  BlackRock Inc. <br> 50 Hudson Yards <br> New York, NY 10001  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4819293<sup>(6</sup>) | 6.1% |
| *Director Nominees and Named Executive Officers* |  |  |
| Keith L. Brownlie | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;92065<sup>(7</sup>) | \*\* |
| Cheryl L. Cohen | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;71500<sup>(8</sup>) | \*\* |
| Herbert J. Conrad | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;93429<sup>(9</sup>) | \*\* |
| Elizabeth Crowley | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;304664<sup>(10</sup>) | \*\* |
| Margo Heath-Chiozzi, M.D. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;301109<sup>(11</sup>) | \*\* |
| Rita I. Jain, M.D. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;50100<sup>(12</sup>) | \*\* |
| Tibor Keler, Ph.D. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;498794<sup>(13</sup>) | \*\* |
| James J. Marino | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;93603<sup>(14</sup>) | \*\* |
| Sam Martin | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;371463<sup>(15</sup>) | \*\* |
| Anthony S. Marucci | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1206505<sup>(16</sup>) | 1.5% |
| Garry A. Neil, M.D. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;71500<sup>(17</sup>) | \*\* |
| Harry H. Penner, Jr. | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;93656<sup>(18</sup>) | \*\* |
| Denice Torres | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;11000<sup>(19</sup>) | \*\* |
| *All Director Nominees and Executive Officers as a group (18 persons)* | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4281773<sup>(20</sup>) | 5.2% |

---

\*

Unless otherwise indicated, the address is c/o Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827.

\*\*

Less than 1%.

(1) Unless otherwise indicated, the persons shown have sole voting and investment power over the shares listed.

(2) Common stock includes all outstanding common stock plus, as required for the purpose of determining beneficial ownership (in accordance with Rule 13d-3(d)(1) of the Securities Exchange Act of 1934, as amended), all common stock subject to any right of acquisition, through exercise or conversion of any security, within 60 days of April 10, 2026.

(3) Based solely on information set forth in a Schedule 13G filed with the SEC by Wellington Management Group LLP on February 10, 2026.

50 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

(4) Based solely on information set forth in a Schedule 13G filed with the SEC by Kynam Capital Management, LP on May 15, 2025.

(5) Based solely on information set forth in a Schedule 13G filed with the SEC by FMR LLC on February 12, 2025.

(6) Based solely on information set forth in a Schedule 13G filed with the SEC by BlackRock Inc. on April 17, 2025.

(7) Includes 91,399 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(8) Includes 71,500 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(9) Includes 90,866 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(10) Includes 295,590 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(11) Includes 286,817 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(12) Includes 50,100 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(13) Includes 491,437 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(14) Includes 91,399 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(15) Includes 338,521 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(16) Includes 1,164,830 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(17) Includes 71,500 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(18) Includes 90,866 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(19) Includes 11,000 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

(20) Please refer to footnotes 7 – 19. Includes for Executive Officers not named in the table, 71,994 shares of common stock and 950,391 shares of common stock underlying options which are or may be exercisable as of April 10, 2026 or 60 days after such date.

Celldex Therapeutics \| 51

------

[**TABLE OF CONTENTS**](#TOC)

Executive Compensation

#### Transactions with Related Persons
It is our policy that all employees and directors, as well as their family members, must avoid any activity that is or has the appearance of conflicting with Celldex's business interest. This policy is included in our Code of Business Conduct and Ethics. All directors and officers of Celldex complete a directors and officers questionnaire at the beginning of each year, in which they are asked to disclose family relationships and other related party transactions. Our Audit Committee must review and approve all related party transactions, as defined in Item 404 of Regulation S-K. Our Audit Committee's procedures for reviewing related party transactions are not in writing. Other than compensation arrangements for our Named Executive Officers and directors, which are described in the section entitled "Executive Compensation," since January 1, 2025, there have been no transactions or series of similar transactions to which we were a party or will be a party, in which:

• the amounts involved exceeded or will exceed $120,000; and

• any of our directors, Executive Officers or holders of more than 5% of our capital stock, or any member of the immediate family of the foregoing persons, had or will have a direct or indirect material interest.

#### THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE ELECTION OF THE DIRECTOR NOMINEES.
52 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 2: Ratification of Independent Public Accounting Firm

### Proposal 2: Ratify The Appointment of Pricewaterhousecoopers LLP as Our Independent Registered Public Accounting Firm for The Year Ending December 31, 2026 (Proposal No. 2)
The Audit Committee has reappointed PricewaterhouseCoopers LLP as our independent registered public accounting firm to audit the financial statements of the Company for the fiscal year ending December 31, 2026 and has further directed that management submit their selection of independent registered public accounting firm for ratification by our stockholders at the Annual Meeting of Stockholders. A representative of PricewaterhouseCoopers LLP is expected to attend the Annual Meeting and will have an opportunity to make a statement, if he or she desires, and will be available to respond to appropriate questions. Neither the accounting firm nor any of its members have any direct or indirect financial interest in or any connection with us in any capacity other than as public registered accounting firm.

#### Principal Accountant Fees and Services
The following table summarizes the fees for professional services rendered by PricewaterhouseCoopers LLP, our independent registered public accounting firm, for each of the last two fiscal years:

---

| | | |
|:---|:---|:---|
| **Fee Category**  | **2025**  | **2024**  |
|  | **(In thousands)**  | **(In thousands)**  |
| Audit Fees | $750 | $680 |
| Audit-Related Fees | 170 |  |
| Tax Fees |  | 109 |
| All Other Fees | 2 | 2 |
| Total Fees | $922 | $791 |

---

#### Audit Fees
Represents fees, including out of pocket expenses, for professional services provided in connection with the audit of our annual audited financial statements, the review of our quarterly financial statements included in our Forms 10-Q, accounting consultations or advice on accounting matters necessary for the rendering of an opinion on our financial statements, services provided in connection with the offerings of our common stock and audit services provided in connection with other statutory or regulatory filings.

#### Audit-Related Fees
Audit-Related fees consist of fees for assurance and related services that are reasonably related to the performance of the audit or review of the Company's consolidated financial statements and are not reported under "Audit Fees." These fees include services pertaining to the Company's implementation of a new enterprise resource planning system.

#### Tax Fees
Tax fees are associated with tax compliance and tax planning related activities.

#### All Other Fees
All other fees consist of fees relating to an accounting research tool and disclosures database.

The Audit Committee is responsible for appointing, setting compensation and overseeing the work of the independent auditors. The Audit Committee has established a policy regarding pre-approval of all auditing services and the terms thereof and non-audit services (other than non-audit services prohibited under Section 10A(g) of the Exchange Act or the applicable rules of the SEC or the Public Company Accounting Oversight Board) to be provided to Celldex by the independent auditor. However, the pre-approval requirement may be waived with respect to the provision of non-audit services for Celldex if the "de minimis" provisions of Section 10A(i)(1)(B) of the Exchange Act are satisfied.

The Audit Committee has considered whether the provision of Audit-Related Fees, Tax Fees, and All Other Fees as described above is compatible with maintaining PricewaterhouseCoopers LLP's independence and has determined that such

Celldex Therapeutics \| 53

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 2: Ratification of Independent Public Accounting Firm

services for fiscal years 2025 and 2024 were compatible. All such services were approved by the Audit Committee pursuant to Rule 2-01 of Regulation S-X under the Exchange Act to the extent that rule was applicable.

The Audit Committee is responsible for reviewing and discussing the audited financial statements with management, discussing with the independent registered public accountants the matters required in Auditing Standards No. 1301, receiving written disclosures from the independent registered public accountants required by the applicable requirements of the Public Company Accounting Oversight Board regarding the independent registered public accountants' communications with the Audit Committee concerning independence and discussing with the independent registered public accountants their independence, and recommending to the Board of Directors that the audit financial statements be included in our annual report on Form 10-K.

#### THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE RATIFICATION OF THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM.
54 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

### Proposal 3: Approval of an Amendment to The 2021 Incentive Plan to Increase The Number of Shares Available for Issuance Under The 2021 Incentive Plan by 3,400,000, From 9,500,000 Plus The Unused Shares of Common Stock Reserved Under The 2008 Incentive Plan, to 12,900,000 Plus The Unused Shares of Common Stock Reserved Under The 2008 Incentive Plan and to Clarify the Tax Withholding Provisions Applicable to Awards Under The 2021 Incentive Plan (Proposal No. 3)

#### General
The primary purpose of the 2021 Incentive Plan is to provide a means whereby eligible employees, officers, non-employee directors and other individual service providers develop a sense of proprietorship and personal involvement in the development and financial success of the Company and to encourage them to devote their best efforts to the business of the Company, thereby advancing the interests of the Company and its stockholders. The Company, by means of the 2021 Incentive Plan, seeks to retain the services of such eligible persons and to provide incentives for such persons to exert maximum efforts for the success of the Company and its subsidiaries.

Our Board believes that the granting of stock options, restricted stock awards and other kinds of equity-based compensation promotes continuity of management and increases incentive and personal interest in the welfare of our Company and alignment with shareholders by those who are primarily responsible for shaping and carrying out our long-range plans and securing our growth and financial success. On March 12, 2026, our Board approved an amendment to increase in the number of shares available for issuance thereunder by 3,400,000 shares and to clarify the tax withholding provisions applicable to awards under the 2021 Incentive Plan, and directed that the amendment be submitted to the shareholders for approval at the Annual Meeting. A copy of the amendment is attached as <u>Annex A</u>.

Our Board believes the increase in the number of shares available for issuance under the 2021 Incentive Plan is needed in order to make awards to expected new hires as a result of the Company planning for commercialization. Our Board also believes that amending the tax withholding provisions of the 2021 Incentive Plan will provide the Company and participants with greater flexibility and certainty in the methods available to satisfy tax withholding obligations arising in connection with awards under the 2021 Incentive Plan.

We believe that our future success will depend in large part upon our ability to attract and retain highly skilled scientific, managerial and marketing personnel. The life sciences industry is highly competitive, and our results are largely attributable to the talents, expertise, efforts and dedication of our employees. Our compensation program, including the granting of equity compensation, is an important component in attracting and recruiting new employees as well as retaining our most experienced and skilled employees.

Equity compensation is also fundamental to our compensation philosophy of paying for performance and aligning the interests of employees with those of our stockholders. We believe that equity awards, and the potential they hold for appreciation through an increase in our stock price, support our pay-for-performance philosophy, provide further incentive to our employees to focus on creating long-term stockholder value and create an ownership culture that links employees' interests with those of our stockholders and our long-term results, performance and financial condition. We also believe that amending the tax withholding provisions of the 2021 Incentive Plan is in the best interests of the Company and its participants. The amendment expands the scope of the tax withholding provision and provides greater clarity and certainty for both the Company and participants regarding the mechanics of tax withholding in connection with equity awards. In particular, the amended tax withholding provision expressly authorizes the Compensation Committee of our Board (the "Committee") to use multiple methods to satisfy tax withholding obligations, including net share issuance.

Accordingly, it is the judgment of our Board of Directors that the approval of this Proposal 3 is in the best interests of our Company and its stockholders.

If the Company's stockholders do not approve the amendment, the Company will continue to operate the 2021 Incentive Plan under its current provisions.

Celldex Therapeutics \| 55

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

#### Description of the 2021 Incentive Plan
The following description of the material terms of the 2021 Incentive Plan is intended to be a summary only. This summary is qualified in its entirety by the full text of the 2021 Incentive Plan, which is incorporated herein by reference to Appendix A of the Company's Definitive Proxy Statement filed on April 27, 2021, as amended on June 15, 2023, June 13, 2024 and June 5, 2025.

***Administration*.** The 2021 Incentive Plan is administered by the Committee. However, the entire Board may act in lieu of the Committee on any matter. The Committee has authority, in its discretion, to approve the persons to whom awards may be granted, to make any combination of awards to participants, to accelerate the exercisability or vesting of an award and to determine the specific terms and conditions of each award, subject to the provisions of the 2021 Incentive Plan. The Committee may also approve rules and regulations for the administration of the 2021 Incentive Plan and amendments or modifications of outstanding awards (except that (i) options and stock appreciation rights ("SARs") cannot be repriced and (ii) options and SARs cannot be cancelled in exchange for cash or another award, in each case, without shareholder approval). The Committee may delegate authority to the chief executive officer and/or other executive officers to grant awards to employees (other than themselves), subject to applicable law and the 2021 Incentive Plan. No awards may be made under the 2021 Incentive Plan on or after the ten (10)-year anniversary of the Effective Date, but the 2021 Incentive Plan will continue thereafter while previously granted awards remain outstanding.

***Eligibility*.** Persons eligible to receive awards under the 2021 Incentive Plan are all employees, officers, directors, consultants, scientific advisors, other individual advisors and other individual service providers of our Company and our subsidiaries, who, in the opinion of the Committee, are in a position to contribute to the success and growth of the Company, or any person who is determined by the Committee to be a prospective employee, officer, director, consultant, scientific advisor, other individual advisor or other individual service provider of the Company or any subsidiary. As of March 31, 2026, the Company and its subsidiaries had a total of 205 employees, including 17 officers and 10 executive officers (who are not included in the number of officers) and eight non-employee directors. Our subsidiary does not have employees and none of the officers and directors of our subsidiaries are eligible for awards under the 2021 Incentive Plan other than those who are eligible as officers or directors of the Company. As of that date, we had approximately five consultants who we have historically granted options to, and no one in the categories of scientific advisors, other individual advisors or other individual service providers. As of March 31, 2026, no person is eligible to participate as a result of a determination by the Committee that that person is a prospective employee, officer, director, consultant, scientific advisor, other individual advisor or other individual service provider of the Company or any subsidiary. As awards under the 2021 Incentive Plan are within the discretion of the Committee, the Company cannot determine how many individuals in each of the categories described above will receive awards.

***Shares Subject to the 2021 Incentive Plan.*** Prior to the proposed increase, an aggregate of (i) 9,500,000 shares of common stock plus (ii) such number of unused shares of common stock reserved under the 2008 Incentive Plan as of the Effective Date that were rolled into the 2021 Incentive Plan, (subsections (i) and (ii) together, the "Share Reserve"), of which approximately 2,680,069 shares remain available for issuance as of March 31, 2026. All such shares of common stock reserved for issuance under the 2021 Incentive Plan may, but need not, be issued in respect of ISOs. In addition, shares of our common stock that relate to any outstanding grants or awards under the 2008 Incentive Plan as of the Effective Date that are forfeited, cancelled or otherwise lapse in accordance with applicable plan terms shall be rolled into the 2021 Incentive Plan and added to the Share Reserve (but not issued in respect of ISOs).

If any option granted under the 2021 Incentive Plan terminates without having been exercised in full or if any award is forfeited or cancelled, the number of shares of common stock as to which such award was forfeited or withheld will be available for future grants under the 2021 Incentive Plan. However, any shares of common stock otherwise issuable that are withheld to satisfy the exercise price of a stock option, tax withholding obligations or repurchased by the Company with stock option proceeds, shall not revert to the 2021 Incentive Plan or be added back to the Share Reserve.

The number of shares of common stock authorized for issuance under the 2021 Incentive Plan and the foregoing share limitations are subject to customary adjustment for stock splits, stock dividends or similar transactions.

Equity-based awards under the 2021 Incentive Plan may vest no earlier than the first anniversary of the date of grant, with limited exceptions for substitute awards, shares of common stock delivered in lieu of fully vested cash awards, director awards vesting on the earlier of the one-year anniversary of grant or the next annual meeting of stockholders and for equity-based awards with respect to up to 5% of the Share Reserve.

***Outside Director Limitation***. The grant date fair value (determined as of the grant date in accordance with Financial Accounting Standards Board Accounting Standards Codification Topic 718, or any successor thereto) of awards granted under the 2021 Incentive Plan to any non-employee director during any calendar year shall not exceed $750,000 (inclusive of any cash awards to a non-employee director for such year that are not made pursuant to the 2021 Incentive Plan); provided that in the case of a new non-employee director, such amount shall be increased to $1,200,000 for the initial year of the non-employee director's term.

56 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

***Terms and Conditions of Options.*** Options granted under the 2021 Incentive Plan may be either ISOs or "nonstatutory stock options" that do not meet the requirements of Section 422 of the Internal Revenue Code of 1986 (the "Code"). The Committee will determine the exercise price of options granted under the 2021 Incentive Plan. The exercise price of stock options may not be less than the fair market value per share of our common stock on the date of grant (or 110% of fair market value in the case of ISOs granted to a ten-percent stockholder).

If on the date of grant the common stock is listed on a stock exchange or is quoted on the automated quotation system of Nasdaq, the fair market value will generally be the closing sale price on the date of grant (or the last trading day before the date of grant if no trades occurred on the date of grant). If no such prices are available, the fair market value will be determined in good faith by the Committee based on the reasonable application of a reasonable valuation method. On April 20, 2026, the closing sale price of a share of common stock on Nasdaq was $34.38.

No option may be exercisable for more than ten years (five years in the case of an ISO granted to a ten-percent stockholder) from the date of grant. Options granted under the 2021 Incentive Plan will be exercisable at such time or times as the Committee prescribes at the time of grant. No employee may receive ISOs that first become exercisable in any calendar year in an amount exceeding $100,000. The Committee may, in its discretion, permit a holder of a nonstatutory option to exercise the option before it has otherwise become exercisable, in which case the shares of our common stock issued to the recipient will continue to be subject to the vesting requirements that applied to the option before exercise.

Generally, the option price may be paid (a) in cash or by certified or bank check or (b) through a broker-assisted exercise program implemented by the Committee in connection with the 2021 Incentive Plan.

No option may be transferred other than by will or by the laws of descent and distribution, and during a recipient's lifetime an option may be exercised only by the recipient. However, the Committee may permit the holder of a nonstatutory option to transfer the award to immediate family members or a family trust for estate planning purposes. The Committee will determine the extent to which a holder of a stock option may exercise the option following termination of service with us.

***Stock Appreciation Rights*.** The Committee may grant SARs independent of or in connection with an option. The Committee will determine the other terms applicable to SARs. The exercise price per share of a SAR will not be less than 100% of the fair market value of a share of our common stock on the date of grant, as determined by the Committee. The maximum term of any SAR granted under the 2021 Incentive Plan is ten years from the date of grant. Generally, each SAR will entitle a participant upon exercise to an amount equal to:

• the excess of the fair market value on the exercise date of one share of our common stock over the exercise price, *multiplied by* 

• the number of shares of common stock covered by the SAR.

Payment may be made in shares of our common stock, in cash, or partly in common stock and partly in cash, all as determined by the Committee.

***Restricted Stock and Restricted Stock Units****.* The Committee may award restricted common stock and/or restricted stock units under the 2021 Incentive Plan. Restricted stock awards consist of shares of common stock that are transferred to a participant subject to restrictions that may result in forfeiture if specified conditions are not satisfied. Restricted stock units confer the right to receive shares of our common stock, cash, or a combination of shares of common stock and cash, at a future date upon or following the attainment of certain conditions specified by the Committee. The restrictions and conditions applicable to each award of restricted stock or restricted stock units may include performance-based conditions. Dividends with respect to restricted stock will only be paid to the holder of the shares at the time that the restricted stock vests. Dividend equivalent amounts may be deemed reinvested in additional restricted stock units, as determined by the Committee in its sole discretion, or paid with respect to restricted stock units when the units vest. Unless the Committee determines otherwise, holders of restricted stock will have the right to vote the shares.

***Performance Shares and Performance Units****.* The Committee may award performance shares and/or performance units under the 2021 Incentive Plan to any eligible employee or other individual service provider other than a non-employee director of the Board. Performance shares and performance units are awards, denominated in either shares of common stock or U.S. dollars, which are earned during a specified performance period subject to the attainment of performance criteria, as established by the Committee. The Committee will determine the restrictions and conditions applicable to each award of performance shares and performance units.

***Incentive Bonus Awards, Other Stock-Based and Cash-Based Awards****.* The Committee may award other types of equity-based or cash-based awards under the 2021 Incentive Plan, including the grant or offer for sale of shares of our common stock that do not have vesting requirements and the right to receive one or more cash payments subject to satisfaction of such conditions as the Committee may impose.

Celldex Therapeutics \| 57

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

***Effect of Certain Corporate Transactions*.** The Committee may, at the time of the grant of an award provide for the effect of a change in control (as defined in the 2021 Incentive Plan) on any award, including (i) accelerating or extending the time periods for exercising, vesting in, or realizing gain from any award, (ii) eliminating or modifying the performance or other conditions of an award, or (iii) providing for the cash settlement of an award for an equivalent cash value, as determined by the Committee. The Committee may, in its discretion and without the need for the consent of any recipient of an award, also take one or more of the following actions contingent upon the occurrence of a change in control: (a) cause any or all outstanding options and SARs to become immediately exercisable, in whole or in part; (b) cause any other awards to become non-forfeitable, in whole or in part; (c) cancel any option or SAR in exchange for a substitute option; (d) cancel any award of restricted stock, restricted stock units, performance shares or performance units in exchange for a similar award of the capital stock of any successor corporation; (e) redeem any restricted stock for cash and/or other substitute consideration with a value equal to the fair market value of an unrestricted share of our common stock on the date of the change in control; (f) cancel any awards in exchange for cash and/or other property equal to the amount, if any, that would have been attained upon the exercise of such award or realization of rights upon a change in control; (g) cancel any outstanding underwater options or SARs for no consideration; or (h) take any other action the Committee deems necessary or appropriate to carry out the terms of any definitive agreement controlling the terms and conditions of the change in control.

***Clawback/Recoupment.*** Awards granted under the 2021 Incentive Plan will be subject to the requirement that the awards be forfeited or amounts repaid to the Company after they have been distributed to the participant (i) to the extent set forth in an award agreement or (ii) to the extent covered by any clawback or recapture policy adopted by the Company from time to time, or any applicable laws that impose mandatory forfeiture or recoupment, under circumstances set forth in such applicable laws.

***Amendment, Termination*.** Our Board may at any time amend the 2021 Incentive Plan for the purpose of satisfying the requirements of the Code, or other applicable law or regulation or for any other legal purpose, provided that, without the consent of our stockholders, the Board may not (a) increase the number of shares of common stock available under the 2021 Incentive Plan, (b) change the group of individuals eligible to receive awards, (c) extend the term of the 2021 Incentive Plan, or (d) reduce or reprice the exercise price of any stock option and/or SAR or cancel any stock option and/or SAR in exchange for cash or another award.

#### Other Information
A "new plan benefits" table, as described in the SEC's proxy rules, is not provided because the grant of options and other awards under the 2021 Incentive Plan is discretionary, and we cannot determine now the specific number or type of options or awards to be granted in the future to any particular person or group. However, please refer to "Executive Compensation" in this Proxy Statement, which provides information on the grants made in the previous fiscal year, and please refer to the description of grants made to our non-employee directors in the last previous year under the heading "Director Compensation" in this Proxy Statement.

#### Material Federal Income Tax Consequences
THE FOLLOWING IS A BRIEF SUMMARY OF THE EFFECT OF FEDERAL INCOME TAXATION UPON THE PARTICIPANTS AND THE COMPANY WITH RESPECT TO THE PURCHASE OF SHARES UNDER THE 2021 INCENTIVE PLAN. THIS SUMMARY DOES NOT PURPORT TO BE COMPLETE AND DOES NOT ADDRESS THE FEDERAL INCOME TAX CONSEQUENCES TO TAXPAYERS WITH SPECIAL TAX STATUS. IN ADDITION, THIS SUMMARY DOES NOT DISCUSS THE PROVISIONS OF THE INCOME TAX LAWS OF ANY MUNICIPALITY, STATE OR FOREIGN COUNTRY IN WHICH THE PARTICIPANT MAY RESIDE, AND DOES NOT DISCUSS ESTATE, GIFT OR OTHER TAX CONSEQUENCES OTHER THAN INCOME TAX CONSEQUENCES. THE COMPANY ADVISES EACH PARTICIPANT TO CONSULT HIS OR HER OWN TAX ADVISOR REGARDING THE TAX CONSEQUENCES OF PARTICIPATION IN THE 2021 INCENTIVE PLAN AND FOR REFERENCE TO APPLICABLE PROVISIONS OF THE CODE.

#### Treatment of Options
The Code treats incentive stock options and nonstatutory stock options differently. However, as to both types of options, no income will be recognized to the optionee at the time of the grant of the options under the 2021 Incentive Plan, nor will our Company be entitled to a tax deduction at that time.

Generally, upon exercise of a nonstatutory stock option (including an option intended to be an incentive stock option but which has not continued to so qualify at the time of exercise), an optionee will recognize ordinary income tax on the excess of the fair market value of the stock on the exercise date over the option price. Our Company will be entitled to a tax deduction in an amount equal to the ordinary income recognized by the optionee in the fiscal year which includes the end of the optionee's taxable year. We will be required to satisfy applicable withholding requirements in order to be entitled to a tax deduction. In general, if an optionee, in exercising a nonstatutory stock option, tenders shares of our common stock in partial or full payment of the option price, no gain or loss will be recognized on the tender. However, if

58 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

the tendered shares were previously acquired upon the exercise of an incentive stock option and the tender is within two years from the date of grant or one year after the date of exercise of the incentive stock option, the tender will be a disqualifying disposition of the shares acquired upon exercise of the incentive stock option.

For incentive stock options, there is no taxable income to an optionee at the time of exercise. However, the excess of the fair market value of the stock on the date of exercise over the exercise price will be taken into account in determining whether the "alternative minimum tax" will apply for the year of exercise. If the shares acquired upon exercise are held until at least two years from the date of grant and more than one year from the date of exercise, any gain or loss upon the sale of such shares, if held as capital assets, will be long-term capital gain or loss (measured by the difference between the sales price of the stock and the exercise price). Under current federal income tax law, a long-term capital gain will be taxed at a rate which is less than the maximum rate of tax on ordinary income. If the two-year and one year holding period requirements are not met (a "disqualifying disposition"), an optionee will recognize ordinary income in the year of disposition in an amount equal to the lesser of (i) the fair market value of the stock on the date of exercise minus the exercise price or (ii) the amount realized on disposition minus the exercise price. The remainder of the gain will be treated as long-term capital gain, depending upon whether the stock has been held for more than a year. If an optionee makes a disqualifying disposition, our Company will be entitled to a tax deduction equal to the amount of ordinary income recognized by the optionee.

In general, if an optionee, in exercising an incentive stock option, tenders shares of common stock in partial or full payment of the option price, no gain or loss will be recognized on the tender. However, if the tendered shares were previously acquired upon the exercise of another incentive stock option and the tender is within two years from the date of grant or one year after the date of exercise of the other option, the tender will be a disqualifying disposition of the shares acquired upon exercise of the other option.

As noted above, the exercise of an incentive stock option could subject an optionee to the alternative minimum tax. The application of the alternative minimum tax to any particular optionee depends upon the particular facts and circumstances which exist with respect to the optionee in the year of exercise. However, as a general rule, the amount by which the fair market value of the common stock on the date of exercise of an option exceeds the exercise price of the option will constitute an item of "adjustment" for purposes of determining the alternative minimum taxable income on which the alternative tax may be imposed. As such, this item will enter into the tax base on which the alternative minimum tax is computed, and may therefore cause the alternative minimum tax to become applicable in any given year.

#### Treatment of Stock Appreciation Rights
Generally, the recipient of a SAR will not recognize any income upon grant of the SAR, nor will our Company be entitled to a deduction at that time. Upon exercise of a SAR, the holder will recognize ordinary income, and our Company generally will be entitled to a corresponding deduction, equal to the fair market value of our common stock at that time.

#### Treatment of Stock Awards
Generally, absent an election to be taxed currently under Section 83(b) of the Code (a "Section 83(b) Election"), there will be no federal income tax consequences to either the recipient or our Company upon the grant of a restricted stock award. At the expiration of the restriction period and the satisfaction of any other restrictions applicable to the restricted shares, the recipient will recognize ordinary income and our Company generally will be entitled to a corresponding deduction equal to the fair market value of the common stock at that time. If a Section 83(b) Election is made within 30 days after the date the restricted stock award is granted, the recipient will recognize an amount of ordinary income at the time of the receipt of the restricted shares, and our Company generally will be entitled to a corresponding deduction, equal to the fair market value (determined without regard to applicable restrictions) of the shares at such time, less any amount paid by the recipient for the shares. If a Section 83(b) Election is made, no additional income will be recognized by the recipient upon the lapse of restrictions on the shares (and prior to the sale of such shares), but, if the shares are subsequently forfeited, the recipient may not deduct the income that was recognized pursuant to the Section 83(b) Election at the time of the receipt of the shares.

The recipient of an unrestricted stock award will recognize ordinary income, and our Company generally will be entitled to a corresponding deduction, equal to the fair market value of our common stock that is the subject of the award when the award is made.

The recipient of a restricted stock unit will recognize ordinary income as and when the units vest and shares of our common stock are issued. The amount of the income will be equal to the fair market value of the shares of our common stock issued at that time, and our Company will be entitled to a corresponding deduction. The recipient of a restricted stock unit will not be permitted to make a Section 83(b) Election with respect to such award.

The federal income tax consequences of performance share awards, performance unit awards, incentive bonus awards, other cash-based awards and other stock-based awards will depend on the terms and conditions of those awards but, in

Celldex Therapeutics \| 59

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

general, participants will be required to recognize ordinary income in an amount equal to the cash and the fair market value of any fully vested shares of our common stock paid, determined at the time of such payment, in connection with such awards.

#### Section 409A
If an award is subject to Section 409A of the Code, but does not comply with the requirements of Section 409A of the Code, the taxable events as described above could apply earlier than described, and could result in the imposition of additional taxes and penalties. Participants are urged to consult with their tax advisors regarding the applicability of Section 409A of the Code to their awards.

#### Potential Limitation on Company Deductions
Section 162(m) of the Code generally disallows a tax deduction for compensation in excess of $1 million paid in a taxable year by a publicly held corporation to its chief executive officer and certain other "covered employees". The Board and the Committee intend to consider the potential impact of Section 162(m) on grants made under the 2021 Incentive Plan, but reserve the right to approve grants of awards for an executive officer that exceeds the deduction limit of Section 162(m).

#### Restrictions on Resale
Certain officers and directors of the Company may be deemed to be "affiliates" of the Company as that term is defined under the Securities Act. The common stock acquired under the 2021 Incentive Plan by an affiliate may be reoffered or resold only pursuant to an effective registration statement or pursuant to Rule 144 under the Securities Act or another exemption from the registration requirements of the Securities Act. It is intended that the shares issuable pursuant to the 2021 Incentive Plan will be registered under the Securities Act of 1933, as amended.

#### Tax Withholding
Under the amendment, the Company may require, as a condition to the grant, vesting, settlement, or delivery of any award, the satisfaction of applicable federal, state, local, and foreign tax withholding obligations. To satisfy such obligations, the Committee is authorized, in its discretion and subject to applicable law, to (i) require cash payments by the participant, (ii) withhold from any amounts otherwise payable in cash to the participant, (iii) withhold a number of whole shares otherwise issuable with respect to the award having an aggregate fair market value equal to the amount of such obligations, (iv) accept delivery by the participant to the Company of shares having an aggregate fair market value equal to the amount of such obligations, and/or (v) facilitate a sale of shares issued upon settlement to generate proceeds sufficient to satisfy such obligations. The number of shares withheld may not exceed such number as is necessary to satisfy the maximum statutory tax rates (or such lower rate as may be necessary to avoid adverse accounting treatment) in the participant's applicable jurisdictions. Shares withheld or delivered to the Company pursuant to this provision shall not again be available for issuance under the 2021 Incentive Plan. For purposes of withholding, fair market value shall be determined pursuant to the Company's consistently applied valuation method for tax withholding.

#### New Plan Benefits
The grant of options and other awards under the 2021 Incentive Plan is discretionary, and we cannot determine now the number or type of options or other awards to be granted in the future to any particular person or group.

#### Options granted under the 2021 Incentive Plan as of March 31, 2026
Since the adoption of the 2021 Incentive Plan through March 31, 2026 we have granted the following stock options under the 2021 Incentive Plan to the individuals and groups listed below. In all cases, the securities underlying such stock options were shares of our common stock. As of the date hereof, we have granted only stock options and no other type of award under the 2021 Incentive Plan.

60 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 3: Approval of an Amendment to the 2021 Omnibus Equity Incentive Plan

---

| | |
|:---|:---|
| **Name and Position**  | **Number of Shares <br> Subject to Stock <br> Options**  |
| **Named Executive Officers**  |  |
| Anthony S. Marucci <br> *President and Chief Executive Officer* | 1324000 |
| Tibor Keler, Ph.D. <br> *Executive Vice President and Chief Scientific Officer* | 460000 |
| Elizabeth Crowley <br> *Senior Vice President, Chief Product Development Officer* | 385000 |
| Margo Heath-Chiozzi, M.D. <br> *Senior Vice President, Regulatory Affairs* | 383500 |
| Sam Martin <br> *Senior Vice President and Chief Financial Officer* | 412000 |
| All current executive officers, as a group  | 4252000 |
| All current directors who are not executive officers, as a group  | 505700 |
| **Each Nominee for Election as a Director**  |  |
| Anthony S. Marucci | 1324000 |
| Keith L. Brownlie | 69900 |
| Cheryl L. Cohen | 71500 |
| Herbert J. Conrad | 69900 |
| Rita I. Jain, M.D. | 50100 |
| James J. Marino | 69900 |
| Garry A. Neil, M.D. | 71500 |
| Harry H. Penner, Jr. | 69900 |
| Denice Torres | 33000 |
| All employees who are not executive officers, as a group  | 3041225 |

---

 **THE BOARD OF DIRECTORS UNANIMOUSLY RECOMMENDS THAT YOU VOTE "*FOR"* THE AMENDMENT TO THE 2021 INCENTIVE PLAN TO INCREASE THE NUMBER OF SHARES AVAILABLE FOR ISSUANCE UNDER THE 2021 INCENTIVE PLAN BY 3,400,000, FROM 9,500,000 PLUS THE UNUSED SHARES OF COMMON STOCK RESERVED UNDER THE 2008 INCENTIVE PLAN, TO 12,900,000 PLUS THE UNUSED SHARES OF COMMON STOCK RESERVED UNDER THE 2008 INCENTIVE PLAN, AND TO CLARIFY THE TAX WITHHOLDING PROVISIONS APPLICABLE TO AWARDS UNDER THE 2021 INCENTIVE PLAN.** 

Celldex Therapeutics \| 61

------

[**TABLE OF CONTENTS**](#TOC)

Proposal 4: Advisory Vote on Executive Compensation

### Proposal 4: Advisory Vote on Executive Compensation (Proposal No. 4)
Under the Dodd-Frank Wall Street Reform and Consumer Protection Act, or the Dodd-Frank Act, and Section 14A of the Securities Exchange Act of 1934, as amended, or the Exchange Act, our stockholders are entitled to vote to approve, on an advisory (nonbinding) basis, the compensation of our Named Executive Officers as disclosed in this proxy statement in accordance with the Securities and Exchange Commission's rules.

As described in detail under the heading "Compensation of Executive Officers — Compensation Discussion and Analysis," our executive compensation programs are designed to retain and incentivize the high quality executives whose efforts are key to our long-term success. Under these programs, our Named Executive Officers are rewarded on the basis of individual and corporate performance measured against established corporate and strategic goals. Please read the section of this proxy statement under the heading "Compensation of Executive Officers — Compensation Discussion and Analysis" for additional details about our executive compensation programs, including information about the fiscal year 2025 compensation of our Named Executive Officers.

The Compensation and Organization Development Committee of our Board of Directors continually reviews the compensation programs for our Named Executive Officers to ensure they achieve the desired goals of aligning our executive compensation structure with our stockholders' interests and current market practices.

We are asking our stockholders to indicate their support for our Named Executive Officer compensation as described in this proxy statement. This proposal, commonly known as a "say-on-pay" proposal, gives our stockholders the opportunity to express their views on our Named Executive Officers' compensation. This vote is not intended to address any specific item of compensation, but rather the overall compensation of our Named Executive Officers and the philosophy, policies and practices described in this proxy statement. Accordingly, we are asking our stockholders to cast a non-binding advisory vote "FOR" the following resolution at the Annual Meeting:

"RESOLVED, that the compensation of the Named Executive Officers, as disclosed in the Company's Proxy Statement for the 2026 Annual Meeting of Stockholders pursuant to Item 402 of Regulation S-K, including the Compensation Discussion and Analysis, compensation tables and narrative disclosure is hereby APPROVED."

The say-on-pay vote is advisory, and therefore not binding on Celldex, the Compensation and Organization Development Committee or our Board of Directors. Nevertheless, our Board of Directors and our Compensation and Organization Development Committee value the opinions of our stockholders, whether expressed through this vote or otherwise, and accordingly, the Board and Compensation and Organization Development Committee intend to consider the results of this vote among the many factors they consider in making determinations in the future regarding executive compensation arrangements.

#### THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THIS PROPOSAL NO. 4.
62 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Stockholder Proposals

### Stockholder Proposals

#### Submitting Proxy Proposals and Director Nominations for the 2027 Annual Meeting

#### Proposals for Inclusion in Our 2027 Proxy Materials
Any stockholder proposals submitted pursuant to Exchange Act Rule 14a-8 for inclusion in Celldex's proxy statement and form of proxy for our 2027 Annual Meeting must be received by Celldex on or before January 4, 2027 in order to be considered for inclusion in our proxy statement and form of proxy. Such proposal must also comply with the requirements as to form and substance established by the SEC if such proposals are to be included in the proxy statement and form of proxy. Any such proposal shall be mailed to: Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827, Attn.: Secretary.

#### Director Nominations for Inclusion in Our 2027 Proxy Materials (Proxy Access)
Any stockholder considering a proxy access nomination should carefully review our bylaws. Under our proxy access bylaw, if a stockholder (or a group of stockholders) who has owned at least 3% of our shares for at least three years and has complied with the other requirements in our bylaws wants us to include director nominees (up to the greater of two nominees or 20% of the Board) in our 2027 proxy materials for election at our 2027 Annual Meeting of Stockholders, then the nominations must be mailed to: Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827, Attn.: Secretary. Any such nomination must be received by us not earlier than December 5, 2026 and not later than January 4, 2027.

#### Other Proposals or Nominations to be Brought before Our 2027 Annual Meeting
Any shareholder considering introducing a nomination or other item of business should carefully review the procedures set forth in our bylaws. Our bylaws state that a stockholder must provide timely written notice of such nomination or proposal and supporting documentation as well as be present at such meeting, either in person or by a representative. A stockholder's notice shall be timely received by Celldex at our principal executive office not less than seventy-five (75) days nor more than one hundred twenty (120) days prior to the anniversary date of the immediately preceding annual meeting (the "Anniversary Date"); provided, however, that in the event the annual meeting is scheduled to be held on a date more than thirty (30) days before the Anniversary Date or more than sixty (60) days after the Anniversary Date, a stockholder's notice shall be timely if received by Celldex at our principal executive office not later than the close of business on the later of (i) the seventy-fifth (75<sup>th</sup>) day prior to the scheduled date of such annual meeting or (ii) the fifteenth (15<sup>th</sup>) day following the day on which such public announcement of the date of such annual meeting is first made by Celldex. Proxies solicited by our Board of Directors will confer discretionary voting authority with respect to these proposals, subject to SEC rules and regulations governing the exercise of this authority. Any such proposal shall be mailed to: Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827, Attn.: Secretary.

Further, if you intend to nominate a director and solicit proxies in support of such director nominee(s) at the 2027 Annual Meeting of Stockholders, you must also provide the notice and additional information required by Rule 14a-19 to: Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827, Attn.: Secretary., no later than April 26, 2027. This deadline under Rule 14a-19 does not supersede any of the timing requirements for advance notice under our by-laws. The supplemental notice and information required under Rule 14a-19 is in addition to the applicable advance notice requirements under our by-laws as described in this section and it shall not extend any such deadline set forth under our by-laws.

Celldex Therapeutics \| 63

------

[**TABLE OF CONTENTS**](#TOC)

Where You Can Find Additional Information

### Where You Can Find Additional Information
The Company files annual, quarterly and current reports, proxy statements and other information with the SEC. Our SEC filings are available to the public over the Internet at the SEC's website at http://www.sec.gov. The SEC's website contains reports, proxy statements and other information regarding issuers, such as Celldex Therapeutics, Inc., that file electronically with the SEC.

The SEC allows the Company to "incorporate by reference" certain information the Company files with it, which means that the Company can disclose important information to you by referring you to those documents. The information incorporated by reference is considered to be part of this Proxy Statement, and information that the Company files later with the SEC will automatically update and supersede previously filed information, including information contained in this document. We are incorporating by reference the following, which include the information required by Item 13(a) of Schedule 14A in connection with Proposal 4:

• Sections of our Annual Report on Form 10-K for the year ended December 31, 2025, filed with the SEC on February 25, 2026: "Part II. Item 7 — Management's Discussion and Analysis of Financial Condition and Results of Operations," "Part II. Item 8 — Financial Statements and Supplementary Data," "Part II. Item 7A — Quantitative and Qualitative Disclosure About Market Risk" and "Part II. Item 9 — Changes in and Disagreements With Accountants on Accounting and Financial Disclosure."

In addition, all documents we file under Section 13(a), 13(c), 14 or 15(d) of the Exchange Act after the date of this Proxy Statement and before the date of the Annual Meeting are incorporated by reference into and deemed a part of this Proxy Statement from the date of filing of those documents.

Any person, including any beneficial owner, to whom this Proxy Statement is delivered may request copies of reports, proxy statements or other information concerning the Company (including the documents incorporated by reference herein) without charge, by written or telephonic request directed to our Corporate Secretary at Celldex Therapeutics, Inc., Perryville III Building, 53 Frontage Road, Suite 220, Hampton, NJ 08827. A request for copies of reports, proxy statements or other information concerning the Company (including the documents incorporated by reference herein) must set forth a good-faith representation that the requesting party was either a holder of record or a beneficial owner of our common stock on April 27, 2026.

64 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

Other Matters

### Other Matters
As of the date of this proxy statement, the Board of Directors does not intend to present at the Annual Meeting any matters other than those described herein and does not presently know of any matters that will be presented by other parties. If any other matter requiring a vote of the stockholders should come before the meeting, it is the intention of the persons named in the proxy to vote with respect to any such matter in accordance with the recommendation of the Board of Directors or, in the absence of such a recommendation, in accordance with the best judgment of the proxy holder.

By Order of the Board of Directors

/s/ Sam Martin

Secretary

Hampton, NJ

May 4, 2026

Celldex Therapeutics \| 65

------

[**TABLE OF CONTENTS**](#TOC)

Annex A

### Annex A

#### Amendment No. 4 to Celldex Therapeutics, Inc. 2021 Omnibus Equity Incentive Plan

#### Approved by the Board of Directors on April 19, 2026
This Agreement amends the Celldex Therapeutics, Inc. 2021 Omnibus Equity Incentive Plan (the "*Plan*"). All capitalized terms not defined herein shall have the meanings set forth in the Plan.

#### Recitals
WHEREAS, Section 17.2 of the Plan reserves to the Board of Directors ("*Board*") of Celldex Therapeutics, Inc. (the "*Company*") the right to amend the Plan from time to time; and

WHEREAS, the Board desires to amend the Plan to increase the number of shares available for awards under the plan by 3,400,000 shares in the manner hereinafter provided subject to approval by the Company's stockholders.

NOW THEREFORE, the Plan is hereby amended as follows:

1. *Amendment to Plan Share Limitation.* 

Section 4.1(a) of the Plan is amended and restated in its entirety as follows:

"(a) Subject to adjustment pursuant to Section 4.3 and any other applicable provisions hereof, the maximum aggregate number of shares of Common Stock which may be issued under all Awards granted to Participants under the Plan shall be (i) 12,900,000 shares plus (ii) such number of unused shares of Common Stock reserved under the Prior Plan as of the Effective Date, which unused reserve shall be rolled into this Plan (subsections (i) and (ii) together, the "*Share Reserve*"); all of which shares may, but need not, be issued in respect of Incentive Stock Options. In addition, there shall be rolled into this Plan and added to the Share Reserve (but not issued in respect of Incentive Stock Options) such number of shares of Common Stock subject to outstanding grants or awards under the Prior Plan as of the Effective Date which are thereafter forfeited, cancelled or otherwise lapse in accordance with the provisions of Section 4.1(b)."

2. *Amendment to Tax Withholding Provision.* 

Section 16.5 of the Plan is amended and restated in its entirety as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 16.5 Tax Withholding. The Company may require, as a condition to the grant, vesting, settlement, or delivery of any Award, the satisfaction of applicable federal, state, local, and foreign tax withholding obligations. To satisfy such obligations, the Committee is authorized, in its discretion and subject to applicable law, to (i) require cash payments by the Participant, (ii) withhold from any amounts otherwise payable in cash to the Participant, (iii) withhold a number of whole shares otherwise issuable with respect to the Award having an aggregate fair market value equal to the amount of such obligations, (iv) accept delivery by the Participant to the Company of shares having an aggregate fair market value equal to the amount of such obligations, and/or (v) facilitate a sale of shares issued upon settlement to generate proceeds sufficient to satisfy such obligations. Notwithstanding the foregoing, the number of shares withheld pursuant to clause (iii) shall not exceed such number as is necessary to satisfy the maximum statutory tax rates (or such lower rate as may be necessary to avoid adverse accounting treatment) in the Participant's applicable jurisdictions. Shares withheld or delivered to the Company pursuant to this section shall not again be available for issuance under the Plan. For purposes of withholding, fair market value shall be determined pursuant to the Company's consistently applied valuation method for tax withholding.

*3. No Other Changes.* Except as set forth herein, the Plan shall remain in full force and effect without modification.

IN WITNESS WHEREOF, the undersigned, a duly authorized officer of the Company, has executed this Amendment as of the date first above written as evidence of its adoption by the Company.

CELLDEX THERAPEUTICS, INC.

By:

/s/ Sam Martin

Name:

Sam Martin

Title:

Senior Vice President and Chief Financial Officer

66 \| Celldex Therapeutics

------

[**TABLE OF CONTENTS**](#TOC)

![[MISSING IMAGE: px_26celldexproxy1pg01-bw.jpg]](px_26celldexproxy1pg01-bw.jpg)

CELLDEX THERAPEUTICS, INC. PERRYVILLE III BUILDING53 FRONTAGE ROAD, SUITE 220 HAMPTON, NJ 08827 SCAN TOVIEW MATERIALS & VOTEVOTE BY INTERNET - www.proxyvote.com or scan the QR Barcode aboveUse the Internet to transmit your voting instructions and for electronic delivery of information. Vote by 11:59 P.M. ET on June 24, 2026. Have your proxy card in hand when you access the web site and follow the instructions to obtain your records and to create an electronic voting instruction form.During The Meeting - Go to www.virtualshareholdermeeting.com/CLDX2026You may attend the meeting via the Internet and vote during the meeting. Have the information that is printed in the box marked by the arrow available and follow the instructions.VOTE BY PHONE - 1-800-690-6903Use any touch-tone telephone to transmit your voting instructions. Vote by 11:59 P.M. ET on June 24, 2026. Have your proxy card in hand when you call and then follow the instructions.VOTE BY MAILMark, sign and date your proxy card and return it in the postage-paid envelope we have provided or return it to Vote Processing, c/o Broadridge, 51 Mercedes Way, Edgewood, NY 11717. TO VOTE, MARK BLOCKS BELOW IN BLUE OR BLACK INK AS FOLLOWS:KEEP THIS PORTION FOR YOUR RECORDSTHIS PROXY CARD IS VALID ONLY WHEN SIGNED AND DATED.DETACH AND RETURN THIS PORTION ONLY R2.09.05.0101 _ 0000706278 TheBoard of Directors recommends you vote FORthefollowing:1.Election of DirectorsNomineesForAgainstAbstain1a.Harry H. Penner, Jr.000TheBoard of Directors recommends you vote FORproposals 2 through 4.1b.Anthony S. Marucci0002.To ratify the appointment ofPricewaterhouseCoopers LLP as our independentregistered public accounting firm for the year1c.Keith L. Brownlie000ending December 31, 2026.1d.Cheryl L. Cohen0003.To approve an amendment to our 2021 OmnibusEquity Incentive Plan, including an increase inthe number of the shares reserved for issuance1e.Herbert J. Conrad000thereunder by 3,400,000 shares to 12,900,000shares and a clarification regarding the taxwithholding provisions applicable to awards1f.Rita I. Jain, M.D.000under the 2021 Incentive Plan.1g.James J. Marino0004.To approve, on an advisory basis, thecompensation of the Company's Named Executive1h.Garry A. Neil, M.D.000Officers as disclosed in the Proxy Statement.1i.Denice Torres000NOTE: In their discretion, upon such other businessas may properly come before the annual meeting oranyadjournment or postponement.Please sign exactly as your name(s) appear(s) hereon. When signing as attorney, executor, administrator, or other fiduciary, please give full title as such. Joint owners should each sign personally. All holders must sign. If a corporation or partnership, please sign in full corporate or partnership name by authorized officer. ForAgainst Abstain00 000 000 0 Signature [PLEASE SIGN WITHIN BOX]DateSignature (Joint Owners)Date

------

[**TABLE OF CONTENTS**](#TOC)

![[MISSING IMAGE: px_26celldexproxy1pg02-4c.jpg]](px_26celldexproxy1pg02-4c.jpg)

Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting:The Notice and Proxy Statement and Annual Report are available at www.proxyvote.comCELLDEX THERAPEUTICS, INC.Annual Meeting of StockholdersJune 25, 2026 9:00 a.m. Eastern TimeThis proxy is solicited by the Board of DirectorsThe undersigned hereby appoints Sam Martin and Anthony S. Marucci, and either of them, as the true and lawful attorneys, agents and proxies of the undersigned, with full power of substitution, and hereby authorizes them to represent and to vote, as designated on the reverse side, all shares of common stock of Celldex Therapeutics, Inc. held of record by the undersigned on April 27, 2026 at the Annual Meeting of Stockholders to be held virtually via the Internet at www.virtualshareholdermeeting.com/CLDX2026, on June 25, 2026 at 9:00 a.m. Eastern Time, or at any adjournment or postponement thereof.This proxy, when properly executed, will be voted in the manner directed herein. If no such direction is made, this proxy will be voted in accordance with the Board of Directors' recommendations.R2.09.05.0102 _ 0000706278Continued and to be signed on reverse side

------