# EDGAR Filing Document

**Accession Number:** 0001174610
**File Stem:** 0002071691-26-009265
**Filing Date:** 2026-4
**Character Count:** 99899
**Document Hash:** d110e33801a947e4d0a5eb912b6a303c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0002071691-26-009265.hdr.sgml**: 20260424

**ACCESSION NUMBER**: 0002071691-26-009265

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260228

**FILED AS OF DATE**: 20260424

**DATE AS OF CHANGE**: 20260424

**PERIOD START**: 20260531

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PROSHARES TRUST
- **CENTRAL INDEX KEY:** 0001174610

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0531

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-21114
- **FILM NUMBER:** 26892989

**BUSINESS ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814
- **BUSINESS PHONE:** 240-497-6400

**MAIL ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** XTRASHARES TRUST
- **DATE OF NAME CHANGE:** 20030409

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PROFUNDS ETF TRUST
- **DATE OF NAME CHANGE:** 20020531

## Series and Classes Contracts Data

### ProShares Ultra Nasdaq Biotechnology (Series ID: S000018718)

| Class ID   | Class Name                           | Ticker Symbol   |
|:---|:---|:---|
| C000051848 | ProShares Ultra Nasdaq Biotechnology | BIB             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ProShares Trust

- **b. Investment Company Act file number:** 811-21114

- **c. CIK number of Registrant:** 0001174610

- **d. LEI of Registrant:** 5493005D9DS7C1P5AM59

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 7272 Wisconsin Avenue

  - **City:** Bethesda

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 20814

  - **Telephone number:** 240-497-6400

**Item A.2. Information about the Series.**

- **a. Name of Series:** ProShares Ultra Nasdaq Biotechnology

- **b. EDGAR series identifier (if any):** S000018718

- **c. LEI of Series:** SL5GC2XPBUL7EXVSNF27

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-05-31

- **b. Date as of which information is reported:** 2026-02-28

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $95192396.54

**Total Liabilities:** $3482243.27

**Net Assets:** $91710153.27

**Cash Not Reported:** $9533496.23

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000051848 | -4.39%               | 4.27%                | 6.03%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-1452174.95             | $321710.96                                 |
| Month 2  | $1110126.30              | $399618.45                                 |
| Month 3  | $519804.82               | $1454949.38                                |

**Designated Index Information**

- **Index Name:** Nasdaq Biotechnology Index

- **Index Identifier:** NBI

### Schedule of Portfolio Investments

| Name                                      | Title                                                   | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| ADMA Biologics, Inc.                      | ADMA Biologics, Inc.                                    | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10990 | NS      | $171114.30    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Absci Corp.                               | Absci Corp.                                             | CUSIP: 00091E109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6944 | NS      | $19026.56     | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| ANI Pharmaceuticals, Inc.                 | ANI Pharmaceuticals, Inc.                               | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |      1037 | NS      | $76634.30     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| AbCellera Biologics, Inc.                 | AbCellera Biologics, Inc.                               | CUSIP: 00288U106<br>LEI: 9845000861BC95FF9F73 | Long             | EC               | CORP              | CA        |     13822 | NS      | $49897.42     | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| Aardvark Therapeutics, Inc.               | Aardvark Therapeutics, Inc.                             | CUSIP: 002942100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1005 | NS      | $12552.45     | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Abivax SA                                 | Abivax SA                                               | CUSIP: 00370M103<br>LEI: 969500D8TMNB184OJU95 | Long             | EC               | CORP              | FR        |      2726 | NS      | $330609.28    | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| ACADIA Pharmaceuticals, Inc.              | ACADIA Pharmaceuticals, Inc.                            | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |      7812 | NS      | $191862.72    | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Aclaris Therapeutics, Inc.                | Aclaris Therapeutics, Inc.                              | CUSIP: 00461U105<br>LEI: 5493000B2LQ9QTW1DF52 | Long             | EC               | CORP              | US        |      5003 | NS      | $14358.61     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Invivyd, Inc.                             | Invivyd, Inc.                                           | CUSIP: 00534A102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12796 | NS      | $21625.24     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp.            | Adaptive Biotechnologies Corp.                          | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |      7049 | NS      | $112924.98    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics, Inc.                  | Spyre Therapeutics, Inc.                                | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |      3583 | NS      | $154104.83    | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Agios Pharmaceuticals, Inc.               | Agios Pharmaceuticals, Inc.                             | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |      2692 | NS      | $81379.16     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Allogene Therapeutics, Inc.               | Allogene Therapeutics, Inc.                             | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10377 | NS      | $28848.06     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals, Inc.             | Alnylam Pharmaceuticals, Inc.                           | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |      6101 | NS      | $2031144.92   | 2.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Alpha Teknova, Inc.                       | Alpha Teknova, Inc.                                     | CUSIP: 02080L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2471 | NS      | $6375.18      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune, Inc.                           | Altimmune, Inc.                                         | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |      4819 | NS      | $20769.89     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Alumis, Inc.                              | Alumis, Inc.                                            | CUSIP: 022307102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4489 | NS      | $133278.41    | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen, Inc.                               | Amgen, Inc.                                             | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |     14536 | NS      | $5642293.76   | 6.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Amicus Therapeutics, Inc.                 | Amicus Therapeutics, Inc.                               | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |     14247 | NS      | $204729.39    | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Amneal Pharmaceuticals, Inc.              | Amneal Pharmaceuticals, Inc.                            | CUSIP: 03168L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     14516 | NS      | $200465.96    | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Amphastar Pharmaceuticals, Inc.           | Amphastar Pharmaceuticals, Inc.                         | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |      2122 | NS      | $42928.06     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Amylyx Pharmaceuticals, Inc.              | Amylyx Pharmaceuticals, Inc.                            | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5071 | NS      | $76927.07     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| AnaptysBio, Inc.                          | AnaptysBio, Inc.                                        | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |      1278 | NS      | $70353.90     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp.                | Anavex Life Sciences Corp.                              | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |      4125 | NS      | $18273.75     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon, Inc.                             | Annexon, Inc.                                           | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6683 | NS      | $37424.80     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals, Inc.             | Apellis Pharmaceuticals, Inc.                           | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |      5839 | NS      | $122385.44    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics, Inc.                 | Apogee Therapeutics, Inc.                               | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2532 | NS      | $177240.00    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Aquestive Therapeutics, Inc.              | Aquestive Therapeutics, Inc.                            | CUSIP: 03843E104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5633 | NS      | $22532.00     | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Arbutus Biopharma Corp.                   | Arbutus Biopharma Corp.                                 | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | CA        |      8881 | NS      | $41385.46     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcellx, Inc.                             | Arcellx, Inc.                                           | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2670 | NS      | $303819.30    | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardelyx, Inc.                             | Ardelyx, Inc.                                           | CUSIP: 039697107<br>LEI: 549300F542QR4SXHCY32 | Long             | EC               | CORP              | US        |     11220 | NS      | $73491.00     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcutis Biotherapeutics, Inc.             | Arcutis Biotherapeutics, Inc.                           | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5656 | NS      | $152542.32    | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcturus Therapeutics Holdings, Inc.      | Arcturus Therapeutics Holdings, Inc.                    | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1312 | NS      | $10797.76     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Argenx SE                                 | Argenx SE                                               | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |      1344 | NS      | $1030740.48   | 1.12%             |  |  |  | No            |                  1 | On Loan: No      |
| ArriVent Biopharma, Inc.                  | ArriVent Biopharma, Inc.                                | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1906 | NS      | $43780.82     | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| Arrowhead Pharmaceuticals, Inc.           | Arrowhead Pharmaceuticals, Inc.                         | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |      6271 | NS      | $396766.17    | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas, Inc.                             | Arvinas, Inc.                                           | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2965 | NS      | $39345.55     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Ascendis Pharma A/S                       | Ascendis Pharma A/S                                     | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |      2835 | NS      | $661972.50    | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| AtaiBeckley, Inc.                         | AtaiBeckley, Inc.                                       | CUSIP: 04650F101<br>LEI: 529900HOVZ0MXOBQ5Y47 | Long             | EC               | CORP              | US        |     16770 | NS      | $60875.10     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Atea Pharmaceuticals, Inc.                | Atea Pharmaceuticals, Inc.                              | CUSIP: 04683R106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3607 | NS      | $16880.76     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Aura Biosciences, Inc.                    | Aura Biosciences, Inc.                                  | CUSIP: 05153U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2932 | NS      | $17269.48     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Aurinia Pharmaceuticals, Inc.             | Aurinia Pharmaceuticals, Inc.                           | CUSIP: 05156V102<br>LEI: 5299008YP2BW4570ML28 | Long             | EC               | CORP              | CA        |      6088 | NS      | $86266.96     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Autolus Therapeutics plc                  | Autolus Therapeutics plc                                | CUSIP: 05280R100<br>LEI: 549300C0KZP8EYROLL02 | Long             | EC               | CORP              | GB        |      9262 | NS      | $15838.02     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics, Inc.                 | Axsome Therapeutics, Inc.                               | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |      2327 | NS      | $381372.03    | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicara Therapeutics, Inc.                 | Bicara Therapeutics, Inc.                               | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2530 | NS      | $42453.40     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics, Inc.                   | Beam Therapeutics, Inc.                                 | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4685 | NS      | $133335.10    | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| BeOne Medicines Ltd.                      | BeOne Medicines Ltd.                                    | CUSIP: 07725L102<br>LEI: 549300JFUK6FRD5MH739 | Long             | EC               | CORP              | CH        |      1454 | NS      | $460903.46    | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicycle Therapeutics plc                  | Bicycle Therapeutics plc                                | CUSIP: 088786108<br>LEI: 213800XKUI6R7GKC3E43 | Long             | EC               | CORP              | GB        |      2136 | NS      | $12239.28     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| BioCryst Pharmaceuticals, Inc.            | BioCryst Pharmaceuticals, Inc.                          | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |      9722 | NS      | $85067.50     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMarin Pharmaceutical, Inc.             | BioMarin Pharmaceutical, Inc.                           | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |      8871 | NS      | $547606.83    | 0.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen, Inc.                              | Biogen, Inc.                                            | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |      6774 | NS      | $1299388.68   | 1.42%             |  |  |  | No            |                  1 | On Loan: No      |
| BioNTech SE                               | BioNTech SE                                             | CUSIP: 09075V102<br>LEI: 894500UZJ5LG1F8J1U58 | Long             | EC               | CORP              | DE        |      4669 | NS      | $514663.87    | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| BioAge Labs, Inc.                         | BioAge Labs, Inc.                                       | CUSIP: 09077V100<br>LEI: 529900NG0C40250Z7875 | Long             | EC               | CORP              | US        |      1656 | NS      | $36879.12     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Black Diamond Therapeutics, Inc.          | Black Diamond Therapeutics, Inc.                        | CUSIP: 09203E105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2631 | NS      | $6498.57      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Bridgebio Pharma, Inc.                    | Bridgebio Pharma, Inc.                                  | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |      8897 | NS      | $591472.56    | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| C4 Therapeutics, Inc.                     | C4 Therapeutics, Inc.                                   | CUSIP: 12529R107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4475 | NS      | $12082.50     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cabaletta Bio, Inc.                       | Cabaletta Bio, Inc.                                     | CUSIP: 12674W109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4445 | NS      | $14757.40     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Candel Therapeutics, Inc.                 | Candel Therapeutics, Inc.                               | CUSIP: 137404109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2535 | NS      | $13308.75     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Caribou Biosciences, Inc.                 | Caribou Biosciences, Inc.                               | CUSIP: 142038108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4316 | NS      | $8200.40      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Caris Life Sciences, Inc.                 | Caris Life Sciences, Inc.                               | CUSIP: 142152107<br>LEI: 549300LX5LO78M5VPY43 | Long             | EC               | CORP              | US        |     13029 | NS      | $262404.06    | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Castle Biosciences, Inc.                  | Castle Biosciences, Inc.                                | CUSIP: 14843C105<br>LEI: 2549007M2Q4HLR1XD252 | Long             | EC               | CORP              | US        |      1348 | NS      | $39860.36     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Centessa Pharmaceuticals plc              | Centessa Pharmaceuticals plc                            | CUSIP: 152309100<br>LEI: 213800GIDAARDSKOI827 | Long             | EC               | CORP              | GB        |      4455 | NS      | $119661.30    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| CG oncology, Inc.                         | CG oncology, Inc.                                       | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3725 | NS      | $219030.00    | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Codexis, Inc.                             | Codexis, Inc.                                           | CUSIP: 192005106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4171 | NS      | $4212.71      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences, Inc.                  | Cogent Biosciences, Inc.                                | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7088 | NS      | $275368.80    | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Coherus Oncology, Inc.                    | Coherus Oncology, Inc.                                  | CUSIP: 19249H103<br>LEI: 5493007IL8W5MV932D26 | Long             | EC               | CORP              | US        |      5581 | NS      | $9320.27      | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Collegium Pharmaceutical, Inc.            | Collegium Pharmaceutical, Inc.                          | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |      1460 | NS      | $60838.20     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Compass Pathways plc                      | Compass Pathways plc                                    | CUSIP: 20451W101<br>LEI: 213800N7CUZIC6QSTZ31 | Long             | EC               | CORP              | GB        |      4351 | NS      | $30021.90     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Contineum Therapeutics, Inc.              | Contineum Therapeutics, Inc., Class A                   | CUSIP: 21217B100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1067 | NS      | $16367.78     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CorMedix, Inc.                            | CorMedix, Inc.                                          | CUSIP: 21900C308<br>LEI: 5299006YIA3L0MBW8358 | Long             | EC               | CORP              | US        |      3638 | NS      | $25938.94     | 0.03%             |  |  |  | No            |                  1 | On Loan: —       |
| Corvus Pharmaceuticals, Inc.              | Corvus Pharmaceuticals, Inc.                            | CUSIP: 221015100<br>LEI: 549300I3AVJ8F75NCX65 | Long             | EC               | CORP              | US        |      3449 | NS      | $62978.74     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Crinetics Pharmaceuticals, Inc.           | Crinetics Pharmaceuticals, Inc.                         | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |      4382 | NS      | $180100.20    | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics, Inc.               | Cullinan Therapeutics, Inc.                             | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2728 | NS      | $42284.00     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics, Inc.                        | Cytokinetics, Inc.                                      | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |      5646 | NS      | $351294.12    | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| CytomX Therapeutics, Inc.                 | CytomX Therapeutics, Inc.                               | CUSIP: 23284F105<br>LEI: 5493004VW2FW0QLL3345 | Long             | EC               | CORP              | US        |      7823 | NS      | $42009.51     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals, Inc.          | Day One Biopharmaceuticals, Inc.                        | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4741 | NS      | $50254.60     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Definium Therapeutics, Inc.               | Definium Therapeutics, Inc.                             | CUSIP: 24477V105<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | CA        |      4548 | NS      | $79362.60     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics, Inc.                 | Denali Therapeutics, Inc.                               | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |      6772 | NS      | $143430.96    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Design Therapeutics, Inc.                 | Design Therapeutics, Inc.                               | CUSIP: 25056L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2630 | NS      | $27457.20     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Disc Medicine, Inc.                       | Disc Medicine, Inc.                                     | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1744 | NS      | $116185.28    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    776976 | PA      | $776975.55    | 0.85%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    776976 | PA      | $776975.55    | 0.85%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    466185 | PA      | $466185.33    | 0.51%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |   1567851 | PA      | $1567850.91   | 1.71%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    466185 | PA      | $466185.33    | 0.51%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    310790 | PA      | $310790.22    | 0.34%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    388488 | PA      | $388487.77    | 0.42%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    155395 | PA      | $155395.11    | 0.17%             |  |  |  | No            |                  2 | On Loan: No      |
| Repurchase Agreement                      | Repurchase Agreement                                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | RA               | CORP              | US        |    310790 | PA      | $310790.22    | 0.34%             |  |  |  | No            |                  2 | On Loan: No      |
| Dyne Therapeutics, Inc.                   | Dyne Therapeutics, Inc.                                 | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6595 | NS      | $103013.90    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics, Inc.               | Edgewise Therapeutics, Inc.                             | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4889 | NS      | $148821.16    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Editas Medicine, Inc.                     | Editas Medicine, Inc.                                   | CUSIP: 28106W103<br>LEI: 5299000AON4Q9NT2JE42 | Long             | EC               | CORP              | US        |      4508 | NS      | $9917.60      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Enanta Pharmaceuticals, Inc.              | Enanta Pharmaceuticals, Inc.                            | CUSIP: 29251M106<br>LEI: 529900SSN4DODDQSN594 | Long             | EC               | CORP              | US        |      1332 | NS      | $19047.60     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics, Inc.                | Enliven Therapeutics, Inc.                              | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2741 | NS      | $81380.29     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Entrada Therapeutics, Inc.                | Entrada Therapeutics, Inc.                              | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1765 | NS      | $21056.45     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Erasca, Inc.                              | Erasca, Inc.                                            | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13101 | NS      | $178959.66    | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Esperion Therapeutics, Inc.               | Esperion Therapeutics, Inc.                             | CUSIP: 29664W105<br>LEI: 549300OFU56UKEWVUS92 | Long             | EC               | CORP              | US        |     11038 | NS      | $36977.30     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Eton Pharmaceuticals, Inc.                | Eton Pharmaceuticals, Inc.                              | CUSIP: 29772L108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1239 | NS      | $21050.61     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolus, Inc.                              | Evolus, Inc.                                            | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |      2993 | NS      | $12869.90     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Exelixis, Inc.                            | Exelixis, Inc.                                          | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |     12381 | NS      | $545506.86    | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| EyePoint, Inc.                            | EyePoint, Inc.                                          | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |      3822 | NS      | $67114.32     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Foghorn Therapeutics, Inc.                | Foghorn Therapeutics, Inc.                              | CUSIP: 344174107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2611 | NS      | $14830.48     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Fortrea Holdings, Inc.                    | Fortrea Holdings, Inc.                                  | CUSIP: 34965K107<br>LEI: 5493000FIVFABOVCDU97 | Long             | EC               | CORP              | US        |      4266 | NS      | $45731.52     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| 4D Molecular Therapeutics, Inc.           | 4D Molecular Therapeutics, Inc.                         | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2638 | NS      | $25483.08     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Fulcrum Therapeutics, Inc.                | Fulcrum Therapeutics, Inc.                              | CUSIP: 359616109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2499 | NS      | $20941.62     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Galapagos NV                              | Galapagos NV                                            | CUSIP: 36315X101<br>LEI: 549300QKJ78IY0IOV655 | Long             | EC               | CORP              | BE        |       668 | NS      | $22484.88     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Genmab A/S                                | Genmab A/S                                              | CUSIP: 372303206<br>LEI: 529900MTJPDPE4MHJ122 | Long             | EC               | CORP              | DK        |      2699 | NS      | $79458.56     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Geron Corp.                               | Geron Corp.                                             | CUSIP: 374163103<br>LEI: 549300T282D7Z2YESL90 | Long             | EC               | CORP              | US        |     29476 | NS      | $49519.68     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences, Inc.                     | Gilead Sciences, Inc.                                   | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |     39904 | NS      | $5943700.80   | 6.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Gossamer Bio, Inc.                        | Gossamer Bio, Inc.                                      | CUSIP: 38341P102<br>LEI: 549300ZOC0N2W6PSFR58 | Long             | EC               | CORP              | US        |     10687 | NS      | $4540.91      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| GRAIL, Inc.                               | GRAIL, Inc.                                             | CUSIP: 384747101<br>LEI: 2549009XSNESW3VE8024 | Long             | EC               | CORP              | US        |      1800 | NS      | $95814.00     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Grifols SA                                | Grifols SA                                              | CUSIP: 398438408<br>LEI: 959800HSSNXWRKBK4N60 | Long             | EC               | CORP              | ES        |      5633 | NS      | $51260.30     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health, Inc.                     | Guardant Health, Inc.                                   | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |      5974 | NS      | $560958.60    | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics, Inc.               | Halozyme Therapeutics, Inc.                             | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |      5430 | NS      | $377547.90    | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings, Inc.        | Harmony Biosciences Holdings, Inc.                      | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2660 | NS      | $75916.40     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Harrow, Inc.                              | Harrow, Inc.                                            | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1710 | NS      | $92647.80     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Humacyte, Inc.                            | Humacyte, Inc.                                          | CUSIP: 44486Q103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8647 | NS      | $9641.41      | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| NovaBridge Biosciences                    | NovaBridge Biosciences                                  | CUSIP: 44975P103<br>LEI: 549300L1A5T19703RR64 | Long             | EC               | CORP              | KY        |      4801 | NS      | $15747.28     | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Ideaya Biosciences, Inc.                  | Ideaya Biosciences, Inc.                                | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |      4048 | NS      | $130345.60    | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina, Inc.                            | Illumina, Inc.                                          | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |      7055 | NS      | $948615.30    | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Immuneering Corp.                         | Immuneering Corp., Class A                              | CUSIP: 45254E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2981 | NS      | $14875.19     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ImmunityBio, Inc.                         | ImmunityBio, Inc.                                       | CUSIP: 45256X103<br>LEI: 529900J9XLBR4HFL4B83 | Long             | EC               | CORP              | US        |     45481 | NS      | $444804.18    | 0.49%             |  |  |  | No            |                  1 | On Loan: —       |
| Immunocore Holdings plc                   | Immunocore Holdings plc                                 | CUSIP: 45258D105<br>LEI: 213800IUE3DFS84BVN18 | Long             | EC               | CORP              | GB        |      2015 | NS      | $65084.50     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant, Inc.                          | Immunovant, Inc.                                        | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8094 | NS      | $224446.62    | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corp.                              | Incyte Corp.                                            | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |      9065 | NS      | $918012.55    | 1.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Indivior Pharmaceuticals, Inc.            | Indivior Pharmaceuticals, Inc.                          | CUSIP: 45579U109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5763 | NS      | $188565.36    | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Inhibrx Biosciences, Inc.                 | Inhibrx Biosciences, Inc.                               | CUSIP: 45720N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       672 | NS      | $49815.36     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed, Inc.                              | Insmed, Inc.                                            | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |      9848 | NS      | $1470601.84   | 1.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Innoviva, Inc.                            | Innoviva, Inc.                                          | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |      3453 | NS      | $79280.88     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics, Inc.               | Intellia Therapeutics, Inc.                             | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |      5348 | NS      | $73695.44     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals, Inc.               | Ionis Pharmaceuticals, Inc.                             | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |      7479 | NS      | $606920.85    | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics, Inc.             | Iovance Biotherapeutics, Inc.                           | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |     18330 | NS      | $70753.80     | 0.08%             |  |  |  | No            |                  1 | On Loan: —       |
| Ironwood Pharmaceuticals, Inc.            | Ironwood Pharmaceuticals, Inc., Class A                 | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |      7512 | NS      | $25691.04     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Janux Therapeutics, Inc.                  | Janux Therapeutics, Inc.                                | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2777 | NS      | $37794.97     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals, Inc.            | KalVista Pharmaceuticals, Inc.                          | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |      2334 | NS      | $37997.52     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Zevra Therapeutics, Inc.                  | Zevra Therapeutics, Inc.                                | CUSIP: 488445206<br>LEI: 254900CU6T74V18Y1W18 | Long             | EC               | CORP              | US        |      2600 | NS      | $23218.00     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Keros Therapeutics, Inc.                  | Keros Therapeutics, Inc.                                | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1406 | NS      | $19951.14     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Kodiak Sciences, Inc.                     | Kodiak Sciences, Inc.                                   | CUSIP: 50015M109<br>LEI: 254900IXI5NI8C9OQE24 | Long             | EC               | CORP              | US        |      2450 | NS      | $65660.00     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech, Inc.                     | Krystal Biotech, Inc.                                   | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |      1339 | NS      | $369081.96    | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology, Inc.                       | Kura Oncology, Inc.                                     | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |      4018 | NS      | $35077.14     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics, Inc.                 | Kymera Therapeutics, Inc.                               | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3322 | NS      | $303464.70    | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Kyverna Therapeutics, Inc.                | Kyverna Therapeutics, Inc.                              | CUSIP: 501976104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2023 | NS      | $16608.83     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Lifecore Biomedical, Inc.                 | Lifecore Biomedical, Inc.                               | CUSIP: 514766104<br>LEI: 549300EHBZ5OM9ND9O43 | Long             | EC               | CORP              | US        |      1730 | NS      | $12456.00     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Larimar Therapeutics, Inc.                | Larimar Therapeutics, Inc.                              | CUSIP: 517125100<br>LEI: 529900NCBZHTTJV6HX73 | Long             | EC               | CORP              | US        |      3953 | NS      | $20990.43     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Legend Biotech Corp.                      | Legend Biotech Corp.                                    | CUSIP: 52490G102<br>LEI: 254900EIUFZTW136H859 | Long             | EC               | CORP              | KY        |      3888 | NS      | $73872.00     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| LENZ Therapeutics, Inc.                   | LENZ Therapeutics, Inc.                                 | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1445 | NS      | $19493.05     | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Lexeo Therapeutics, Inc.                  | Lexeo Therapeutics, Inc.                                | CUSIP: 52886X107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3370 | NS      | $24196.60     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Ligand Pharmaceuticals, Inc.              | Ligand Pharmaceuticals, Inc.                            | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |       909 | NS      | $180263.79    | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Lyell Immunopharma, Inc.                  | Lyell Immunopharma, Inc.                                | CUSIP: 55083R203<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       979 | NS      | $23496.00     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| MBX Biosciences, Inc.                     | MBX Biosciences, Inc.                                   | CUSIP: 55287L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2073 | NS      | $67476.15     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Madrigal Pharmaceuticals, Inc.            | Madrigal Pharmaceuticals, Inc.                          | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |      1048 | NS      | $452736.00    | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| MannKind Corp.                            | MannKind Corp.                                          | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |     14180 | NS      | $46510.40     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Maravai LifeSciences Holdings, Inc.       | Maravai LifeSciences Holdings, Inc., Class A            | CUSIP: 56600D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6696 | NS      | $23837.76     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Maze Therapeutics, Inc.                   | Maze Therapeutics, Inc.                                 | CUSIP: 578784100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2222 | NS      | $101300.98    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Medpace Holdings, Inc.                    | Medpace Holdings, Inc.                                  | CUSIP: 58506Q109<br>LEI: 549300H8TYEUVTW14A54 | Long             | EC               | CORP              | US        |      1301 | NS      | $587739.76    | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Mesoblast Ltd.                            | Mesoblast Ltd.                                          | CUSIP: 590717401<br>LEI: 529900J5ALF3JG921927 | Long             | EC               | CORP              | AU        |      2264 | NS      | $35884.40     | 0.04%             |  |  |  | No            |                  1 | On Loan: —       |
| Mineralys Therapeutics, Inc.              | Mineralys Therapeutics, Inc.                            | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3654 | NS      | $106916.04    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharmaceuticals, Inc.               | Mirum Pharmaceuticals, Inc.                             | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |      2373 | NS      | $219004.17    | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna, Inc.                             | Moderna, Inc.                                           | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |     18039 | NS      | $966349.23    | 1.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics, Inc.             | Monte Rosa Therapeutics, Inc.                           | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3007 | NS      | $53374.25     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Neumora Therapeutics, Inc.                | Neumora Therapeutics, Inc.                              | CUSIP: 640979100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7715 | NS      | $26925.35     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences, Inc.              | Neurocrine Biosciences, Inc.                            | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |      4604 | NS      | $608879.00    | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurogene, Inc.                           | Neurogene, Inc.                                         | CUSIP: 64135M105<br>LEI: 529900A7VIY892SZVW73 | Long             | EC               | CORP              | US        |       715 | NS      | $16795.35     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Novavax, Inc.                             | Novavax, Inc.                                           | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |      7504 | NS      | $76090.56     | 0.08%             |  |  |  | No            |                  1 | On Loan: —       |
| Nuvalent, Inc.                            | Nuvalent, Inc., Class A                                 | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3335 | NS      | $340003.25    | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics, Inc.                  | Nurix Therapeutics, Inc.                                | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4680 | NS      | $74739.60     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocular Therapeutix, Inc.                  | Ocular Therapeutix, Inc.                                | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |      9837 | NS      | $87942.78     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Olema Pharmaceuticals, Inc.               | Olema Pharmaceuticals, Inc.                             | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3632 | NS      | $87894.40     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Omeros Corp.                              | Omeros Corp.                                            | CUSIP: 682143102<br>LEI: 549300CJWLXX2MXVVV71 | Long             | EC               | CORP              | US        |      3274 | NS      | $39451.70     | 0.04%             |  |  |  | No            |                  1 | On Loan: —       |
| OmniAb, Inc.                              | OmniAb, Inc.                                            | CUSIP: 68218J103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6647 | NS      | $11432.84     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Orchestra BioMed Holdings, Inc.           | Orchestra BioMed Holdings, Inc.                         | CUSIP: 68572M106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2607 | NS      | $11418.66     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC Pharmaceuticals, Inc.                | ORIC Pharmaceuticals, Inc.                              | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |      4497 | NS      | $60484.65     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics, Inc.                  | Oruka Therapeutics, Inc.                                | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |      2236 | NS      | $76940.76     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| PTC Therapeutics, Inc.                    | PTC Therapeutics, Inc.                                  | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |      3707 | NS      | $252780.33    | 0.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacific Biosciences of California, Inc.   | Pacific Biosciences of California, Inc.                 | CUSIP: 69404D108<br>LEI: 529900F1BWRE1M0KZN89 | Long             | EC               | CORP              | US        |     13941 | NS      | $23420.88     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacira BioSciences, Inc.                  | Pacira BioSciences, Inc.                                | CUSIP: 695127100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1986 | NS      | $43513.26     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| PepGen, Inc.                              | PepGen, Inc.                                            | CUSIP: 713317105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3175 | NS      | $19748.50     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Personalis, Inc.                          | Personalis, Inc.                                        | CUSIP: 71535D106<br>LEI: 549300EZ2NYFK7H0US48 | Long             | EC               | CORP              | US        |      4101 | NS      | $37155.06     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Phathom Pharmaceuticals, Inc.             | Phathom Pharmaceuticals, Inc.                           | CUSIP: 71722W107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3285 | NS      | $41259.60     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Phibro Animal Health Corp.                | Phibro Animal Health Corp., Class A                     | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |       946 | NS      | $51642.14     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines, Inc.          | Praxis Precision Medicines, Inc.                        | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1155 | NS      | $388946.25    | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Precigen, Inc.                            | Precigen, Inc.                                          | CUSIP: 74017N105<br>LEI: 549300XCWNQU35K64G19 | Long             | EC               | CORP              | US        |     16338 | NS      | $61921.02     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Prime Medicine, Inc.                      | Prime Medicine, Inc.                                    | CUSIP: 74168J101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8335 | NS      | $38507.70     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics, Inc.            | Protagonist Therapeutics, Inc.                          | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2887 | NS      | $265834.96    | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Puma Biotechnology, Inc.                  | Puma Biotechnology, Inc.                                | CUSIP: 74587V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2326 | NS      | $13258.20     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pyxis Oncology, Inc.                      | Pyxis Oncology, Inc.                                    | CUSIP: 747324101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2875 | NS      | $4226.25      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Quantum-Si, Inc.                          | Quantum-Si, Inc.                                        | CUSIP: 74765K105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9030 | NS      | $8636.29      | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Rani Therapeutics Holdings, Inc.          | Rani Therapeutics Holdings, Inc., Class A               | CUSIP: 753018100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4504 | NS      | $6170.48      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| RAPT Therapeutics, Inc.                   | RAPT Therapeutics, Inc.                                 | CUSIP: 75382E208<br>LEI: 549300MB473BIU78ES48 | Long             | EC               | CORP              | US        |      1279 | NS      | $74156.42     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Rapport Therapeutics, Inc.                | Rapport Therapeutics, Inc.                              | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2201 | NS      | $63895.03     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Recursion Pharmaceuticals, Inc.           | Recursion Pharmaceuticals, Inc., Class A                | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23743 | NS      | $87136.81     | 0.10%             |  |  |  | No            |                  1 | On Loan: —       |
| Regeneron Pharmaceuticals, Inc.           | Regeneron Pharmaceuticals, Inc.                         | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |      4769 | NS      | $3727784.23   | 4.06%             |  |  |  | No            |                  1 | On Loan: No      |
| REGENXBIO, Inc.                           | REGENXBIO, Inc.                                         | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |      2337 | NS      | $21126.48     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics, Inc.                  | Relay Therapeutics, Inc.                                | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8003 | NS      | $82110.78     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group, Inc.                     | Replimune Group, Inc.                                   | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |      3622 | NS      | $27708.30     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Revolution Medicines, Inc.                | Revolution Medicines, Inc.                              | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |      8927 | NS      | $910732.54    | 0.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals, Inc.              | Rhythm Pharmaceuticals, Inc.                            | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |      3082 | NS      | $285793.86    | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| Rigel Pharmaceuticals, Inc.               | Rigel Pharmaceuticals, Inc.                             | CUSIP: 766559702<br>LEI: 529900KPTNUS5J8K9K66 | Long             | EC               | CORP              | US        |       838 | NS      | $29112.12     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Rocket Pharmaceuticals, Inc.              | Rocket Pharmaceuticals, Inc.                            | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |      4990 | NS      | $24999.90     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Sagimet Biosciences, Inc.                 | Sagimet Biosciences, Inc., Class A                      | CUSIP: 786700104<br>LEI: 2549002OT2F8BV0VPD02 | Long             | EC               | CORP              | US        |      1432 | NS      | $8176.72      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology, Inc.                  | Sana Biotechnology, Inc.                                | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12300 | NS      | $51783.00     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Sanofi SA                                 | Sanofi SA                                               | CUSIP: 80105N105<br>LEI: 549300E9PC51EN656011 | Long             | EC               | CORP              | FR        |     12219 | NS      | $594576.54    | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics, Inc.                | Sarepta Therapeutics, Inc.                              | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |      4838 | NS      | $81084.88     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara, Inc.                              | Savara, Inc.                                            | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |      9395 | NS      | $56557.90     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp.                | Scholar Rock Holding Corp.                              | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |      4710 | NS      | $208511.70    | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Cartesian Therapeutics, Inc.              | Cartesian Therapeutics, Inc.                            | CUSIP: 816212112<br>LEI: 529900NMN0LACZOL7C43 | Long             |  | CORP              | US        |      9785 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Septerna, Inc.                            | Septerna, Inc.                                          | CUSIP: 81734D104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2067 | NS      | $59984.34     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Silence Therapeutics plc                  | Silence Therapeutics plc                                | CUSIP: 82686Q101<br>LEI: 213800SSURRJBX85SQ91 | Long             | EC               | CORP              | GB        |      2169 | NS      | $11799.36     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| SIGA Technologies, Inc.                   | SIGA Technologies, Inc.                                 | CUSIP: 826917106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3307 | NS      | $21396.29     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ARS Pharmaceuticals, Inc.                 | ARS Pharmaceuticals, Inc.                               | CUSIP: 82835W108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4564 | NS      | $42353.92     | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| Sionna Therapeutics, Inc.                 | Sionna Therapeutics, Inc.                               | CUSIP: 829401108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2061 | NS      | $75308.94     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Solid Biosciences, Inc.                   | Solid Biosciences, Inc.                                 | CUSIP: 83422E204<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3598 | NS      | $22343.58     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics, Inc.                  | Stoke Therapeutics, Inc.                                | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |      2638 | NS      | $96049.58     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Structure Therapeutics, Inc.              | Structure Therapeutics, Inc.                            | CUSIP: 86366E106<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |      3086 | NS      | $194356.28    | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Summit Therapeutics, Inc.                 | Summit Therapeutics, Inc.                               | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     34375 | NS      | $570281.25    | 0.62%             |  |  |  | No            |                  1 | On Loan: —       |
| Supernus Pharmaceuticals, Inc.            | Supernus Pharmaceuticals, Inc.                          | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |      2648 | NS      | $144925.04    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Sutro Biopharma, Inc.                     | Sutro Biopharma, Inc.                                   | CUSIP: 869367201<br>LEI: 5493005U6P15VD25P851 | Long             | EC               | CORP              | US        |         1 | NS      | $20.47        | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Syndax Pharmaceuticals, Inc.              | Syndax Pharmaceuticals, Inc.                            | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |      4014 | NS      | $87143.94     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics, Inc.                  | Tango Therapeutics, Inc.                                | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6219 | NS      | $69279.66     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Tarsus Pharmaceuticals, Inc.              | Tarsus Pharmaceuticals, Inc.                            | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1961 | NS      | $148094.72    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Taysha Gene Therapies, Inc.               | Taysha Gene Therapies, Inc.                             | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12648 | NS      | $57295.44     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Tectonic Therapeutic, Inc.                | Tectonic Therapeutic, Inc.                              | CUSIP: 878972108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       864 | NS      | $20260.80     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Tenaya Therapeutics, Inc.                 | Tenaya Therapeutics, Inc.                               | CUSIP: 87990A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7688 | NS      | $4319.12      | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Tempus AI, Inc.                           | Tempus AI, Inc., Class A                                | CUSIP: 88023B103<br>LEI: 2549009LA0KWRAGQBX50 | Long             | EC               | CORP              | US        |      7982 | NS      | $425041.50    | 0.46%             |  |  |  | No            |                  1 | On Loan: —       |
| 10X Genomics, Inc.                        | 10X Genomics, Inc., Class A                             | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |      5379 | NS      | $123985.95    | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Terns Pharmaceuticals, Inc.               | Terns Pharmaceuticals, Inc.                             | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |      4160 | NS      | $175219.20    | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Third Harmonic Bio, Inc.                  | Third Harmonic Bio, Inc.                                | CUSIP: 88427A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1662 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Travere Therapeutics, Inc.                | Travere Therapeutics, Inc.                              | CUSIP: 89422G107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4131 | NS      | $123062.49    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Trevi Therapeutics, Inc.                  | Trevi Therapeutics, Inc.                                | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5921 | NS      | $70578.32     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corp.                    | Twist Bioscience Corp.                                  | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |      2823 | NS      | $132455.16    | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Tyra Biosciences, Inc.                    | Tyra Biosciences, Inc.                                  | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2464 | NS      | $82075.84     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceutical, Inc.           | Ultragenyx Pharmaceutical, Inc.                         | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |      4455 | NS      | $104202.45    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| United Therapeutics Corp.                 | United Therapeutics Corp.                               | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |      1988 | NS      | $1001753.20   | 1.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Upstream Bio, Inc.                        | Upstream Bio, Inc.                                      | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2495 | NS      | $19161.60     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanda Pharmaceuticals, Inc.               | Vanda Pharmaceuticals, Inc.                             | CUSIP: 921659108<br>LEI: 529900AY8VOOQBKJ0O70 | Long             | EC               | CORP              | US        |      2729 | NS      | $24315.39     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Vaxcyte, Inc.                             | Vaxcyte, Inc.                                           | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |      6044 | NS      | $373156.56    | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Ventyx Biosciences, Inc.                  | Ventyx Biosciences, Inc.                                | CUSIP: 92332V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3295 | NS      | $46031.15     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte, Inc.                            | Veracyte, Inc.                                          | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |      3650 | NS      | $133553.50    | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Vera Therapeutics, Inc.                   | Vera Therapeutics, Inc., Class A                        | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2950 | NS      | $120330.50    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Vericel Corp.                             | Vericel Corp.                                           | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |      2335 | NS      | $83312.80     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals, Inc.              | Vertex Pharmaceuticals, Inc.                            | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |     11581 | NS      | $5753788.23   | 6.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Viatris, Inc.                             | Viatris, Inc.                                           | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |     53183 | NS      | $794022.19    | 0.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Vir Biotechnology, Inc.                   | Vir Biotechnology, Inc.                                 | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6424 | NS      | $58394.16     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Vor BioPharma, Inc.                       | Vor BioPharma, Inc.                                     | CUSIP: 929033207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       778 | NS      | $12012.32     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Voyager Therapeutics, Inc.                | Voyager Therapeutics, Inc.                              | CUSIP: 92915B106<br>LEI: 54930082S4XVR0ZWCC74 | Long             | EC               | CORP              | US        |      2721 | NS      | $11156.10     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor, Inc.                              | Xencor, Inc.                                            | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |      3298 | NS      | $42115.46     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Xenon Pharmaceuticals, Inc.               | Xenon Pharmaceuticals, Inc.                             | CUSIP: 98420N105<br>LEI: 549300XV44Q9Z1MIPQ03 | Long             | EC               | CORP              | CA        |      3568 | NS      | $154244.64    | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings, Inc.            | Xeris Biopharma Holdings, Inc.                          | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7662 | NS      | $46891.44     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Zai Lab Ltd.                              | Zai Lab Ltd.                                            | CUSIP: 98887Q104<br>LEI: 549300P2UYQ9U5LY1T58 | Long             | EC               | CORP              | KY        |      1808 | NS      | $34749.76     | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Zenas Biopharma, Inc.                     | Zenas Biopharma, Inc.                                   | CUSIP: 98937L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2478 | NS      | $65295.30     | 0.07%             |  |  |  | No            |                  1 | On Loan: —       |
| Zymeworks, Inc.                           | Zymeworks, Inc.                                         | CUSIP: 98985Y108<br>LEI: 894500AHOYAGYLYZJL67 | Long             | EC               | CORP              | US        |      3456 | NS      | $80490.24     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                       | Total Return Swap                                       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |      6179 | NC      | $2613913.81   | 2.85%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                       | Total Return Swap                                       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |      3646 | NC      | $2414689.32   | 2.63%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                       | Total Return Swap                                       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |      4291 | NC      | $5817987.37   | 6.34%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                       | Total Return Swap                                       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |      2639 | NC      | $2651090.10   | 2.89%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                       | Total Return Swap                                       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |      2484 | NC      | $3308295.63   | 3.61%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                       | Total Return Swap                                       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | US        |       633 | NC      | $-1662820.74  | -1.81%            |  |  |  | No            |                  2 | On Loan: No      |
| Alkermes plc                              | Alkermes plc                                            | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | IE        |      7624 | NS      | $229482.40    | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| GH Research plc                           | GH Research plc                                         | CUSIP: N/A<br>LEI: 875500HKJS7QQG6EWH62       | Long             | EC               | CORP              | IE        |      2864 | NS      | $42530.40     | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| Jazz Pharmaceuticals plc                  | Jazz Pharmaceuticals plc                                | CUSIP: N/A<br>LEI: 635400GAUMJCLEZRRV50       | Long             | EC               | CORP              | IE        |      2806 | NS      | $533196.12    | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Kiniksa Pharmaceuticals International plc | Kiniksa Pharmaceuticals International plc, Class A      | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | GB        |      2086 | NS      | $92806.14     | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings plc                     | MeiraGTx Holdings plc                                   | CUSIP: N/A<br>LEI: 54930007YV6NYIOGFZ57       | Long             | EC               | CORP              | KY        |      3717 | NS      | $28100.52     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Novocure Ltd.                             | Novocure Ltd.                                           | CUSIP: N/A<br>LEI: 213800YPP55UMHWA4826       | Long             | EC               | CORP              | JE        |      5171 | NS      | $70687.57     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corp. plc                        | Prothena Corp. plc                                      | CUSIP: N/A<br>LEI: 5299009ZXQ8NIIJ8OL30       | Long             | EC               | CORP              | IE        |      2485 | NS      | $21544.95     | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd.                     | Roivant Sciences Ltd.                                   | CUSIP: N/A<br>LEI: 549300DL466NY5J6U724       | Long             | EC               | CORP              | BM        |     32114 | NS      | $929379.16    | 1.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Royalty Pharma plc                        | Royalty Pharma plc, Class A                             | CUSIP: N/A<br>LEI: 549300FGFN7VOK8BZR03       | Long             | EC               | CORP              | GB        |     19729 | NS      | $911677.09    | 0.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Jyong Biotech Ltd.                        | Jyong Biotech Ltd.                                      | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | KY        |      3511 | NS      | $7513.54      | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Theravance Biopharma, Inc.                | Theravance Biopharma, Inc.                              | CUSIP: N/A<br>LEI: 5493007VTSXP4Z6MIW52       | Long             | EC               | CORP              | KY        |      2340 | NS      | $42705.00     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| AC Immune SA                              | AC Immune SA                                            | CUSIP: N/A<br>LEI: 967600VLQ0ZC2HSOG765       | Long             | EC               | CORP              | CH        |      4636 | NS      | $13583.48     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| CRISPR Therapeutics AG                    | CRISPR Therapeutics AG                                  | CUSIP: N/A<br>LEI: 506700O6IRRIQLT3W370       | Long             | EC               | CORP              | CH        |      4400 | NS      | $264616.00    | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| INVESCO GOVT AND AGCY LEX                 | INVESCO GOVERNMENT & AGENCY PORTFOLIO OPEN-END FUND USD | CUSIP: 825252885<br>LEI: O37NHJVF7S22I1ONOU83 | Long             | STIV             | RF                | US        |   1662868 | NS      | $1662868.50   | 1.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Alvotech SA                               | Alvotech SA                                             | CUSIP: N/A<br>LEI: 222100DCZBOWV5DZ8372       | Long             | EC               | CORP              | LU        |     14454 | NS      | $57671.46     | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Kamada Ltd.                               | Kamada Ltd.                                             | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | IL        |      2664 | NS      | $23176.80     | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| UroGen Pharma Ltd.                        | UroGen Pharma Ltd.                                      | CUSIP: N/A<br>LEI: 549300C0YCX7CG2G5D50       | Long             | EC               | CORP              | IL        |      2162 | NS      | $46915.40     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Newamsterdam Pharma Co. NV                | Newamsterdam Pharma Co. NV                              | CUSIP: N/A<br>LEI: 984500B6549TF6E14D36       | Long             | EC               | CORP              | NL        |      5236 | NS      | $185668.56    | 0.20%             |  |  |  | No            |                  1 | On Loan: —       |
| Pharvaris NV                              | Pharvaris NV                                            | CUSIP: N/A<br>LEI: 9845003BE146D3B75D32       | Long             | EC               | CORP              | NL        |      2958 | NS      | $83977.62     | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| uniQure NV                                | uniQure NV                                              | CUSIP: N/A<br>LEI: 724500RPCTZLFYJZ3S98       | Long             | EC               | CORP              | NL        |      2877 | NS      | $44967.51     | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| WaVe Life Sciences Ltd.                   | WaVe Life Sciences Ltd.                                 | CUSIP: N/A<br>LEI: 54930070006GPKFYZ813       | Long             | EC               | CORP              | SG        |      7723 | NS      | $107581.39    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-03-30

**Name of Applicant:** ProShares Trust

**Signature:** Maria Clem Sell

**Name of Signer:** Maria Clem Sell

**Title:** Treasurer