# EDGAR Filing Document

**Accession Number:** 0001000694
**File Stem:** 0001000694-26-000011
**Filing Date:** 2026-2
**Character Count:** 34895
**Document Hash:** e8b0283cf4aef9186d7687c2b7186a1c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001000694-26-000011.hdr.sgml**: 20260226

**ACCESSION NUMBER**: 0001000694-26-000011

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 14

**CONFORMED PERIOD OF REPORT**: 20260226

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20260226

**DATE AS OF CHANGE**: 20260226

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** NOVAVAX INC
- **CENTRAL INDEX KEY:** 0001000694
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 222816046
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-26770
- **FILM NUMBER:** 26681772

**BUSINESS ADDRESS:**
- **STREET 1:** 21 FIRSTFIELD RD
- **CITY:** GAITHERSBURG
- **STATE:** MD
- **BUSINESS PHONE:** 240-268-2000

**MAIL ADDRESS:**
- **STREET 1:** 21 FIRSTFIELD RD
- **CITY:** GAITHERSBURG
- **STATE:** MD

?xml version='1.0' encoding='ASCII'? nvax-20260226

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**Washington, D.C. 20549** 

**FORM 8-K**

**CURRENT REPORT**

**PURSUANT TO SECTION 13 OR 15(d)**

**OF THE SECURITIES EXCHANGE ACT OF 1934** 

**Date of Report (Date of earliest event reported): February 26, 2026**

**NOVAVAX, INC.**

**(Exact name of registrant as specified in charter)** 

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| | | |
|:---|:---|:---|
| **Delaware** | **0-26770** | **22-2816046** |
| **(State or Other Jurisdiction**<br>**of Incorporation)** | **(Commission File Number)** | **(I.R.S. Employer**<br>**Identification No.)** |

---

**21 Firstfield Road**

**Gaithersburg, Maryland 20878**

**(Address of Principal Executive Offices, including Zip Code)** 

**(240) 268-2000**

**(Registrant's telephone number, including area code)** 

**(Former name or former address, if changed since last report.)** 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 ☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 ☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 ☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 ☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

**Securities registered pursuant to Section 12(b) of the Act:**

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| | | |
|:---|:---|:---|
| **Title of each class** | **Trading <br>Symbol(s)** | **Name of each exchange on which <br>registered** |
| Common Stock, Par Value $0.01 per share | NVAX | The Nasdaq Global Select Market |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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**Item 2.02. Results of Operations and Financial Condition.**

*Third Quarter Financial Results*

On February 26, 2026, Novavax, Inc. (the "Company") issued a press release announcing the Company's financial results for the quarter ended December 31, 2025. A copy of this press release is attached as Exhibit 99.1 to this Current Report on Form 8-K.

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**Item 9.01. Financial Statements and Exhibits.**

(d) **Exhibits.**

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| | |
|:---|:---|
| **Exhibit No.** | **Description** |
| <u>[99.1](nvaxq4-25earningspressrele.htm)</u> | <u>[Press release, dated](nvaxq4-25earningspressrele.htm)[Febr](nvaxq4-25earningspressrele.htm)[uary 26, 2026](nvaxq4-25earningspressrele.htm)[, regarding the Company's financial results for the quarter ended](nvaxq4-25earningspressrele.htm)[December](nvaxq4-25earningspressrele.htm)[3](nvaxq4-25earningspressrele.htm)[1](nvaxq4-25earningspressrele.htm)[, 202](nvaxq4-25earningspressrele.htm)[5](nvaxq4-25earningspressrele.htm)[.](nvaxq4-25earningspressrele.htm)</u> |
| 104 | Cover Page Interactive Data File (formatted as Inline XBRL). |

---

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**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | | |
|:---|:---|:---|
| | NOVAVAX, INC. | NOVAVAX, INC. |
| Date: February 26, 2026 | By: | /s/ Mark J. Casey |
|  | Name: | Mark J. Casey |
|  | Title: | Executive Vice President, Chief Legal Officer and Corporate Secretary |

---

## Exhibit 99.1

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| | |
|:---|:---|
| <br>Press Release | ![image_0.jpg](image_0.jpg) |

---

**Novavax Reports Fourth Quarter and Full Year 2025 Financial Results and Operational Highlights**

• *Pfizer agreement announced in January 2026 for non-exclusive license to utilize Matrix-M*<sup>®</sup> *in two infectious disease areas*

• *Multiple Material Transfer Agreements signed in 2025 and Q1 2026 with pharmaceutical companies, including major global pharmaceutical companies exploring the utility of Matrix-M for their vaccine portfolios* 

• *Successful execution of Sanofi partnership with $225 million in milestones earned in full year 2025* 

• *Total revenue of $147 million in the fourth quarter of 2025 and $1.1 billion for the full year 2025*

• *Continued advancement of early-stage pipeline with the intention to enter the clinic as early as 2027*

• *Year end 2025 Cash of $751 million* 

• *Novavax exceeded its full year 2025 R&D and SG&A expense reduction goals and is improving future targets* 

**GAITHERSBURG, Md., February 26, 2026** – Novavax, Inc. (Nasdaq: NVAX) today announced its financial results and operational highlights for the fourth quarter and year ended December 31, 2025.

"In 2025, we made significant progress on our corporate strategy, marked with the successful achievement of key milestones under our Sanofi agreement, progress towards potential new partnerships, in the form of multiple MTAs signed with other parties enabling experimentation with our Matrix-M<sup>®</sup> adjuvant technology and the advancement of our own R&D efforts," said John C. Jacobs, President and Chief Executive Officer, Novavax. "With a strong start to 2026, including the recently announced Pfizer Matrix-M agreement, we look forward to commercial and clinical development execution from our partners, advancing our R&D efforts and the potential for more partnerships as we drive vaccine innovation and value creation from our technology."

**Fourth Quarter 2025 and Recent Highlights**

***Key Business Highlights***

<br> <br> <br>

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<br> <br> <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• In January 2026, Novavax entered into a license agreement with Pfizer for use of Novavax's Matrix-M adjuvant in vaccine development. Under the terms of the agreement, Pfizer was granted a non-exclusive license for Matrix-M use in two infectious disease areas.

oNovavax received an upfront payment of $30 million in the first quarter of 2026 and has the potential for up to $500 million in additional development and sales milestones. In addition, Novavax is eligible to receive high-mid-single digit percentage royalties on sales products incorporating Matrix-M.

oPfizer will be solely responsible for the development and commercialization of its products utilizing Matrix-M and Novavax will be responsible for the supply of Matrix-M.

oThis partnership has the potential to generate billions of dollars of revenue for Novavax over the life of the agreement.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Novavax continued successful execution of the Sanofi partnership with $225 million in milestones earned in full year 2025, including $50 million earned in the fourth quarter of 2025, upon marketing authorization transfers for European Union and U.S. markets.

oIn December 2025, Sanofi shared positive Phase 1/2 data from their influenza-COVID-19 combination programs and their belief that these data support the high probability of demonstrating non-inferiority in Phase 3 trials that would compare the new vaccine against the widely used regimen where both the flu and COVID-19 vaccines are co-administered.

oSanofi has stated they are working with regulators on next steps for these combination programs.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Novavax has multiple material transfer agreements (MTA) with pharmaceutical companies, including major global pharmaceutical companies, who are evaluating the potential of Matrix-M in their portfolio of vaccine products.

oIn the fourth quarter of 2025, Novavax signed a new MTA with a large pharmaceutical company to explore the utility of Matrix-M in its portfolio.

oIn February 2026, Novavax expanded an existing MTA with a major global pharmaceutical company to explore an additional field.

oIn February 2026, Novavax signed a new MTA with an oncology company.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Other partners continue to demonstrate the value of Novavax's technology with Takeda achieving 12% market share with Nuvaxovid<sup>®</sup> in Japan and the R21/Matrix-M, malaria vaccine, marketed by Serum Institute of India, continues its successful launch with 30 million doses sold since its launch in mid-2024, achieving over 80% market share.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The Company continued advancement of early-stage candidates and Matrix-M technology.

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<br> <br> <br>

oPreclinical research ongoing for Clostridioides difficile colitis (C. diff), varicella-zoster virus (shingles), and respiratory syncytial virus combinations vaccine candidates.

oSignificant progress made on preclinical candidates, for example the newest preclinical data from C. diff vaccine candidate provided encouraging results.

oNovavax intends to enter the clinic with at least one program as early as 2027.

oNovavax continued exploration of its adjuvant technology to expand its utility both within infectious disease and potentially beyond, such as oncology.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Novavax exceeded its full year 2025 GAAP and Non-GAAP research and development (R&D) and selling, general and administrative (SG&A) expense reduction goals and is improving future targets.

oNon-GAAP full year R&D and SG&A expenses, net of R&D reimbursements and at midpoint of range, are now targeted to be $325 million and $225 million for 2026 and 2027, respectively, and newly added 2028 is targeted to be at $200 million or below.

**Fourth Quarter and Full Year 2025 Revenue** 

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| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Fourth Quarter** | **Fourth Quarter** | **Fourth Quarter** | **Fourth Quarter** | **Full Year** | **Full Year** | **Full Year** | **Full Year** |
| **$ in millions** | **Q4 2025** | **Q4 2024** | **Q4**<br>**Chg.** | **%** | **FY**<br>**2025** | **FY**<br>**2024** | **FY**<br>**Chg.** | **%** |
| Nuvaxovid™ Sales <sup>1</sup> | $20 | $50 | ($30) | NM | $625 | $190 | $435 | NM |
| Supply Sales <sup>2</sup> | 19 | 9 | 10 | NM | 60 | 23 | 37 | NM |
| **Product Sales** | 39 | 59 | (20) | (34)% | 685 | 213 | 472 | NM |
| Sanofi <sup>3</sup> | 98 | 30 | 68 | NM | 386 | 459 | (73) | (16)% |
| Takeda | 8 | (4) | 12 | NM | 42 | 1 | 41 | NM |
| Other Partners <sup>4</sup> | 2 | 3 | (1) | NM | 10 | 9 | 1 | 11% |
| **Licensing, Royalties and Other Revenue** | 108 | 29 | 79 | NM | 438 | 469 | (31) | (7)% |
| **Total Revenue** | $**147** | $**88** | $**59** | **67%** | $**1123** | $**682** | $**441** | **65%** |

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*Notes* 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;*1.Nuvaxovid Sales reflects product sales where Novavax is the commercial market lead and records revenue related to the sales and distribution of its COVID-19 vaccine.* 

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<br> <br> <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;*2.Supply Sales includes sales of finished product, adjuvant and other supplies from Novavax to its license partners.*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;*3.Sanofi includes revenue recognized under the license agreement including upfront payments, milestones, royalties and transition services reimbursement.*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;*4.Other Partners include upfront payments, royalties and milestone revenue under licensing agreements including Serum Institute and SK bioscience.* 

**Fourth Quarter and Full Year 2025 Financial Results** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Total revenue** for the fourth quarter of 2025 was $147 million, a 67% increase compared to $88 million in the same period in 2024. Total revenue for the full year 2025 was $1,123 million, a 65% increase compared to $682 million for the full year 2024. Full year 2025 total revenue included $625 million of Nuvaxovid product sales, the vast majority of which were associated with settlement of Advance Purchase Agreements and related to cash received in prior years.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Cost of sales** for the fourth quarter of 2025 was $22 million, compared to $37 million in the same period in 2024. Cost of sales for the full year 2025 was $73 million, compared to $203 million for the full year 2024. The decrease in both periods was mainly driven by cost reductions resulting from the sale of Novavax's Czech Republic manufacturing facility, lower manufacturing overhead, scrap and inventory write-offs, and decreased sales volumes.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **R&D expenses** for the fourth quarter of 2025 were $76 million, compared to $104 million in the same period in 2024. R&D expenses for the full year 2025 were $342 million, compared to $391 million for the full year 2024. R&D transition services expenses reimbursed by Sanofi in the fourth quarter and full year of 2025 were $28 million and $92 million, respectively. For the fourth quarter and full year of 2025, Non-GAAP R&D expenses, net of Sanofi reimbursement, decreased by 50% and 33%, respectively when compared to the prior periods. These reductions were driven by the ongoing Novavax cost reduction program as it streamlines operations to make targeted R&D investments.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **SG&A expenses** for the fourth quarter of 2025 were $34 million, a 56% decrease compared to $78 million for the same period in 2024. SG&A expenses for the full year 2025 were $157 million, a 53% decrease compared to $337 million for the full year 2024. The decrease in both periods was primarily due to the transition of lead commercial activities to Sanofi and the elimination of commercial infrastructure plus the ongoing general administrative cost reduction program.

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<br> <br> <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Net income** for the fourth quarter of 2025 was $18 million, compared to net loss of $81 million in the same period in 2024. Net income for the full year 2025 was $440 million compared to a net loss of $187 million for the full year 2024.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Cash, cash equivalents, marketable securities and restricted cash (Cash)** were $751 million as of December 31, 2025, compared to $938 million as of December 31, 2024. In February 2026, Novavax announced a $330 million credit facility with MidCap Financial, including an initial capital draw of $50 million. The credit facility was put in place to further strengthen Novavax's balance sheet and provide access to non-dilutive capital as Novavax advances its growth strategy. Leerink Partners acted as exclusive financial advisor and Latham & Watkins acted as legal advisor to Novavax on the credit facility.

**Financial Framework** 

**Full Year 2026 Financial Guidance** 

Novavax provides Full Year 2026 Financial Guidance for Combined R&D and SG&A Expenses and Non-GAAP Combined R&D and SG&A Expenses and currently expects to achieve the following results:

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| | |
|:---|:---|
| $ in millions | **Full Year 2026**<br>(as of February 26, 2026) |
| Combined R&D and SG&A Expenses | $380 - $420 |
| Less: R&D Reimbursements | ($70 - $80) |
| Non-GAAP Combined R&D and SG&A Expenses | $310 - $340 |

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Non-GAAP Combined R&D and SG&A Expenses exclude R&D Reimbursements, which are amounts reimbursed by Novavax's license partners. See "Non-GAAP Financial Measures" below. R&D Reimbursements are recorded as revenue under Licensing, Royalties and Other Revenue.

**Full Year 2026 Revenue Framework** 

Novavax transitioned lead commercial responsibility of Nuvaxovid beginning with the 2025-2026 COVID-19 vaccination season to Sanofi for select markets. Since Novavax is reliant on Sanofi's sales forecasts for certain revenue components, these are not included in the Full Year 2026 Revenue Framework. For 2026, Novavax currently expects to achieve Adjusted Total Revenue<sup>4</sup> of between $230 million and $270 million.

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| | |
|:---|:---|
| <br>$ in millions | **Full Year 2026**<br>(as of February 26, 2026) |
| Nuvaxovid Product Sales<sup>1</sup> | $35 - $45 |
| Adjusted Supply Sales<sup>2</sup> | $40 - $50 |
| Adjusted Licensing, Royalties and Other Revenue<sup>3</sup> | $155 - $175 |
| Adjusted Total Revenue<sup>4</sup> | $230 - $270 |
| Sanofi Supply Sales, Sanofi Royalties and Sanofi influenza-COVID-19 combination and Matrix-M Milestones | No guidance |

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| | |
|:---|:---|
| **Revenue Category** | **Revenue Framework Footnotes** |
| Nuvaxovid Product Sales<sup>1</sup> | $35 million to $45 million in Nuvaxovid Product Sales by Novavax under existing APA and commercial agreements. |
| Adjusted Supply Sales<sup>2</sup> | $40 million to $50 million in Adjusted Supply Sales associated with collaborations with the Serum Institute on R21/Matrix-M and collaboration partners for COVID-19 vaccine, including Serum and Takeda. |
| Adjusted Licensing, Royalties and Other Revenue<sup>3</sup>  | o$70 million to $80 million in R&D Reimbursement. Under the Sanofi co-exclusive licensing agreement (CLA), Novavax is eligible to receive reimbursement for costs incurred related to select R&D and technology transfer activities during the transition performance period. <br>o$50 to $60 million in Other Partner related revenue including royalties and milestones from Pfizer, Serum on R21/Matrix-M and collaboration partners for COVID-19 vaccine, including Serum and Takeda. Includes a $30 million upfront payment under the Pfizer agreement received in the first quarter of 2026.<br>o$35 million amortization related to the $500 million Upfront Payment and the $50 million Database Lock Milestone. Revenue recognition will occur over the transition performance period. |
| Adjusted Total Revenue<sup>4</sup> | oAdjusted Total Revenue is a Non-GAAP Financial Measure. Adjusted Total Revenue is total revenue excluding Sanofi Supply Sales, Sanofi Royalties and Sanofi influenza-COVID-19 Combination and Matrix-M related Milestones. See "Non-GAAP Financial Measures" |

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**Components of Revenue excluded from the Full Year 2026 Revenue Framework are described below.** 

Sanofi Supply Sales

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Novavax will sell Nuvaxovid commercial supply to Sanofi for the 2026-2027 COVID-19 vaccination season and the reimbursement for this supply will be recorded as product sales.

Sanofi Royalties

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Sanofi will lead commercial activities for the 2026-2027 COVID-19 vaccination season in select markets, including the U.S. Novavax is eligible to receive royalties in the high teens to low twenties percent on Sanofi sales.

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<br> <br> <br>

Sanofi Influenza-COVID-19 Combination and Matrix-M Related Milestones

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Novavax is eligible to receive up to $350 million in Phase 3 development and commercial launch milestone payments associated with Sanofi influenza-COVID-19 combination products.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• For each new vaccine using Matrix-M, Novavax is eligible to receive up to $200 million in launch and sales milestones and mid-single digit sales royalties for 20 years.

**Conference Call**

Novavax will host its quarterly conference call today at 8:30 a.m. Eastern Time (ET). To join the call without operator assistance, you may register and enter your phone number at https://registrations.events/easyconnect/9610065/rec5pyQ9YRaX3NyBf/ to receive an instant automated call back. You may also dial direct to be entered into the call by an operator. The dial-in numbers for the conference call are (888) 880-3330 (Domestic) or (+1) (646) 357-8766 (International). Participants will be prompted to request to join the Novavax, Inc. call. A replay of the conference call will be available starting at 11:30 a.m. ET on February 26, 2026, until 11:59 p.m. ET on March 5, 2026. To access the replay by telephone, dial (800) 770-2030 (Domestic) or (+1) (609) 800-9909 (International) and use passcode 9610065#.

A webcast of the conference call can also be accessed on the Novavax website at ir.novavax.com/events. A replay of the webcast will be available on the Novavax website until March 25, 2026.

**About Novavax** 

Novavax, Inc. (Nasdaq: NVAX) tackles some of the world's most pressing health challenges with its scientific expertise in vaccines and its proven technology platform, including its Matrix-M adjuvant and protein-based nanoparticles. The Company's growth strategy focuses on maximizing the impact of its cutting-edge technology by forging strategic partnerships for its Matrix-M adjuvant and R&D assets. Please visit novavax.com and LinkedIn for more information.

**Non-GAAP Financial Measures** 

The Company presents the following non-GAAP financial measures in this press release: Non-GAAP Combined R&D and SG&A Expenses, Adjusted Total Revenue and Adjusted Licensing, Royalties and Other Revenue. Non-GAAP financial measures refer to financial information adjusted from financial measures prepared in accordance with accounting principles generally accepted in the United States (GAAP). The Company

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believes that the presentation of these adjusted financial measures is useful to investors as they provide additional information on comparisons between periods by including certain items that affect overall comparability. The Company uses these non-GAAP financial measures for business planning purposes and to consider underlying trends of its business. Non-GAAP financial measures should be considered in addition to, and not as an alternative for, the Company's reported results prepared in accordance with GAAP. Our use of non-GAAP financial measures may differ from similar measures reported by other companies and may not be comparable to other similarly titled measures. The Company is unable to reconcile these revenue forward-looking non-GAAP financial measures to the most directly comparable GAAP measures without unreasonable effort because the Company is reliant on Sanofi sales forecasts for certain revenue categories, which are not available.

**Forward-Looking Statements** 

This press release contains forward-looking statements relating to the future of Novavax, its mission; its corporate strategy and operating plans, objectives and prospects; its value drivers and strategic priorities; its partnerships, including expectations with respect to potential royalties, milestones and other commercial objectives, and cost reimbursement, Matrix-M's potential utility in partners' vaccine portfolios and plans for additional potential partnering activities; the development of Novavax's clinical and preclinical product candidates and pipeline advancement opportunities, including with respect to new Matrix formulations; the conduct, timing and potential results from clinical trials, conducted by Novavax or its partners, and other preclinical and postmarketing studies; expectations as to the timing and outcome of future and pending regulatory filings and actions; full year 2026 financial guidance and revenue framework; and Novavax's future financial or business performance. Novavax cautions that these forward-looking statements are subject to numerous risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. These risks and uncertainties include, without limitation, Novavax's ability to successfully and timely obtain and maintain full U.S. FDA licensure or foreign regulatory approvals necessary to manufacture, market, distribute, or deliver its COVID-19 vaccine; the impact of delays in obtaining regulatory approval, including regulatory decisions impacting labeling, approval or authorization, including the scope of the indicated population, product dosage, manufacturing processes, shelf life, safety, for our product candidates; challenges in conducting the postmarketing commitment ("PMC") study, our ability to obtain adequate additional funding to maintain our current level of operations and fund the further development of our vaccine candidates; challenges related to Novavax's partnership with Sanofi, including collaboration on the Nuvaxovid PMC, and in pursuing additional partnership opportunities; challenges

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<br> <br> <br>

satisfying, alone or together with partners, various safety, efficacy, and product characterization requirements, including those related to process qualification, assay validation and stability testing, necessary to satisfy applicable regulatory authorities; challenges or delays in conducting clinical trials or studies for its product candidates; manufacturing, distribution or export delays or challenges; Novavax's substantial dependence on Serum Institute of India Pvt. Ltd. and Serum Life Sciences Limited for co-formulation and filling Novavax's COVID-19 vaccine and the impact of any delays or disruptions in their operations; the impact of potential legislative, regulatory, or policy changes under the current presidential administration, including any adverse impact funding for vaccine research and development, reimbursement for vaccines and their administration, vaccine mandates and recommendations, and public perception of vaccine importance; uncertainty with respect to pricing, third-party reimbursement and healthcare reform; uncertainty in the regulatory pathway for Novavax's COVID -19 Vaccine; the impact of any new or changes in interpretations of existing trade measures, including tariffs, embargoes, sanctions, import restrictions, and export licensing requirements; difficulty obtaining scarce raw materials and supplies including for its proprietary adjuvant; resource constraints, including human capital and manufacturing capacity; constraints on Novavax's ability to pursue planned regulatory pathways, alone or with partners, in multiple jurisdictions simultaneously, leading to staggering of regulatory filings, and potential regulatory actions; Novavax's ability to timely deliver doses; challenges in obtaining commercial adoption and market acceptance of its COVID-19 vaccine or any COVID-19 variant strain containing formulation, or for its CIC vaccine candidates, stand-alone influenza vaccine candidates or other candidates; challenges meeting contractual requirements under agreements with multiple commercial, governmental, and other entities, including requirements to deliver doses that may require Novavax to refund portions of upfront and other payments previously received or result in reduced future payments pursuant to such agreements; challenges related to the seasonality of vaccinations against COVID-19; challenges related to the demand for vaccinations against COVID-19 or influenza; challenges in identifying and successfully pursuing innovation expansion opportunities; Novavax's expectations as to expenses and cash needs may prove not to be correct for reasons such as changes in plans or actual events being different than its assumptions; and those other risk factors identified in the "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" sections of Novavax's Annual Report on Form 10-K for the year ended December 31, 2025, and subsequent Quarterly Reports on Form 10-Q, as filed with the Securities and Exchange Commission (SEC). We caution investors not to place considerable reliance on forward-looking statements contained in this press release. You are encouraged to read our filings with the SEC, available at <u>www.sec.gov</u> and <u>www.novavax.com</u>, for a discussion of these and other risks and

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<br> <br> <br>

uncertainties. The forward-looking statements in this press release speak only as of the date of this document, and we undertake no obligation to update or revise any of the statements. Our business is subject to substantial risks and uncertainties, including those referenced above. Investors, potential investors, and others should give careful consideration to these risks and uncertainties.

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| | | | | |
|:---|:---|:---|:---|:---|
| **NOVAVAX, INC.** | **NOVAVAX, INC.** | **NOVAVAX, INC.** | **NOVAVAX, INC.** | **NOVAVAX, INC.** |
| **CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS**<br>**(in thousands, except per share information)** | **CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS**<br>**(in thousands, except per share information)** | **CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS**<br>**(in thousands, except per share information)** | **CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS**<br>**(in thousands, except per share information)** | **CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS**<br>**(in thousands, except per share information)** |
| | **Three Months Ended** | **Three Months Ended** | **Twelve Months Ended** | **Twelve Months Ended** |
| | **December 31,** | **December 31,** | **December 31,** | **December 31,** |
|  | **2025** | 2024 | **2025** | 2024 |
|  | **(unaudited)** | **(unaudited)** |  |  |
| Revenue: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Product sales | $**39197** | $59250 | $**685041** | $213202 |
| &nbsp;&nbsp;&nbsp;&nbsp;Licensing, royalties and other | **107942** | 29061 | **438438** | 468960 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total revenue | **147139** | 88311 | **1123479** | 682162 |
| Expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of sales | &nbsp;&nbsp;&nbsp;&nbsp;**22104** | 36669 | **73040** | 202739 |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development | **75876** | 104380 | **342320** | 391169 |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative | **34122** | 78342 | **157479** | 337185 |
| &nbsp;&nbsp;&nbsp;&nbsp;Impairment of assets held for sale | **807** | - | **97845** | - |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total expenses | **132909** | 219391 | **670684** | 931093 |
| Income (loss) from operations | **14230** | (131080) | **452795** | (248931) |
| Interest expense | **(5824)** | (7585) | **(22547)** | (20075) |
| Loss on debt extinguishment | **-** | - | **(28714)** | - |
| Gain on disposition of Novavax CZ assets | **-** | 51949 | **-** | 51949 |
| Other income, net | **9497** | 13135 | **40633** | 40442 |
| Income (loss) before income tax expense | **17903** | (73581) | **442167** | (176615) |
| &nbsp;&nbsp;&nbsp;&nbsp;Income tax expense  | **(376)** | (7449) | **(1865)** | (10884) |
| Net income (loss) | $**17527** | $(81030) | $**440302** | $(187499) |
| Net income (loss) per share: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $**0.11** | $(0.51) | $**2.72** | $(1.23) |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $**0.11** | $(0.51) | $**2.58** | $(1.23) |
| Weighted average number of common shares outstanding: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | **162527** | 160241 | **161991** | 152190 |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | **165182** | 160241 | **173103** | 152190 |

---

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<br> <br> <br>

**SELECTED CONSOLIDATED BALANCE SHEET DATA**

**(in thousands)**

---

| | | |
|:---|:---|:---|
|  | **December 31,**<br>**2025** | **December 31,**<br>**2024** |
| Cash and cash equivalents | $**240634** | $**530230** |
| Marketable securities | **494450** | **392888** |
| Total restricted cash | **15418** | **15062** |
| Total current assets | **978276** | **1128942** |
| Working capital&nbsp;&nbsp;&nbsp;&nbsp; | **518326** | **&nbsp;&nbsp;&nbsp;&nbsp;(25474)** |
| Total assets | **1176512** | **1560418** |
| Convertible notes payable | **244213** | **169684** |
| Total stockholders' deficit | **(127753)** | **(623841)** |

---

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| | | | | |
|:---|:---|:---|:---|:---|
| **NOVAVAX, INC.** | **NOVAVAX, INC.** | **NOVAVAX, INC.** | **NOVAVAX, INC.** | **NOVAVAX, INC.** |
| **Reconciliation of GAAP to NON-GAAP Financial Results**<br>**(unaudited)** | **Reconciliation of GAAP to NON-GAAP Financial Results**<br>**(unaudited)** | **Reconciliation of GAAP to NON-GAAP Financial Results**<br>**(unaudited)** | **Reconciliation of GAAP to NON-GAAP Financial Results**<br>**(unaudited)** | **Reconciliation of GAAP to NON-GAAP Financial Results**<br>**(unaudited)** |
| ($ in millions) | **Three Months Ended** | **Three Months Ended** | **Twelve Months Ended** | **Twelve Months Ended** |
|  | **December 31,** | **December 31,** | **December 31,** | **December 31,** |
|  | **2025** | 2024 | 2025 | 2024 |
| **Total Revenue** | $147.1 | $88.3 | $1123.5 | $682.2 |
| Adjustments: |  |  |  |  |
| Sanofi Supply Sales | 9.2 | 0 | 15.7 | 0 |
| Sanofi Royalties | 1.6 | 0 | 5.8 | 0 |
| **Adjusted Total Revenue** | $**136.4** | $**88.3** | $**1102.0** | $**682.2** |
| **R&D Expenses** | $75.9 | $104.4 | $342.3 | $391.2 |
| Adjustments: |  |  |  |  |
| R&D Reimbursement | 28.1 | 8.7 | 91.6 | 19.4 |
| **Non-GAAP R&D Expenses** | $**47.8** | $**95.7** | $**250.7** | $**371.7** |
| **Combined R&D and SG&A Expenses** | $110.0 | $182.7 | $499.8 | $728.4 |
| Adjustments: |  |  |  |  |
| R&D Reimbursement | 28.1 | 8.7 | 91.6 | 19.4 |
| **Non-GAAP Combined R&D and SG&A Expenses** | $**81.9** | $**174.0** | $**408.2** | $**708.9** |

---

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<br> <br> <br>

**Contacts:**

<u>Investors</u>

Luis Sanay, CFA

240-268-2022

ir@novavax.com

<u>Media</u>

Yvonne Sprow

844-264-8571

media@novavax.com