# EDGAR Filing Document

**Accession Number:** 0000918294
**File Stem:** 0000918294-23-000068
**Filing Date:** 2023-2
**Character Count:** 90400
**Document Hash:** 877a7f5208f7fcac8b0c87c74f168a38
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000918294-23-000068.hdr.sgml**: 20230224

**ACCESSION NUMBER**: 0000918294-23-000068

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230224

**DATE AS OF CHANGE**: 20230224

**PERIOD START**: 20221231

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** T. Rowe Price Equity Series, Inc.
- **CENTRAL INDEX KEY:** 0000918294
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** MD
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-07143
- **FILM NUMBER:** 23667576

**BUSINESS ADDRESS:**
- **STREET 1:** 100 EAST PRATT STREET
- **CITY:** BALTIMORE
- **STATE:** MD
- **ZIP:** 21202
- **BUSINESS PHONE:** 410-345-2000

**MAIL ADDRESS:**
- **STREET 1:** 100 EAST PRATT STREET
- **CITY:** BALTIMORE
- **STATE:** MD
- **ZIP:** 21202

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PRICE T ROWE EQUITY SERIES INC
- **DATE OF NAME CHANGE:** 19940131

## Series and Classes Contracts Data

### T. Rowe Price Health Sciences Portfolio (Series ID: S000002083)

| Class ID   | Class Name                                 | Ticker Symbol   |
|:---|:---|:---|
| C000005448 | T. Rowe Price Health Sciences Portfolio    | QAAGZX          |
| C000005449 | T. Rowe Price Health Sciences Portfolio-II | QAAHBX          |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** T. ROWE PRICE EQUITY SERIES, INC.

- **b. Investment Company Act file number:** 811-07143

- **c. CIK number of Registrant:** 0000918294

- **d. LEI of Registrant:** 549300U8GAQGX2UFFV03

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 100 East Pratt Street

  - **City:** Baltimore

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 21202

  - **Telephone number:** 410-345-2000

**Item A.2. Information about the Series.**

- **a. Name of Series:** T. Rowe Price Health Sciences Portfolio

- **b. EDGAR series identifier (if any):** S000002083

- **c. LEI of Series:** 23LI9YJ7764IBT5W0K91

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2022-12-31

- **b. Date as of which information is reported:** 2022-12-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $730896337.64

**Total Liabilities:** $1604361.97

**Net Assets:** $729291975.67

**Assets Attributable to Miscellaneous Securities:** $30003351.32

**Delayed Delivery Securities:** $458582.48

**Cash Not Reported:** $6412.07

**Currency Risk Metrics (dv01):**

- 

**Credit Spread Risk - Investment Grade (dv01):**

- **3-Month:** 0.000000 | **1-Year:** 0.000000 | **5-Year:** 0.000000 | **10-Year:** 0.000000 | **30-Year:** 0.000000

**Credit Spread Risk - Non-Investment Grade (dv01):**

- **3-Month:** 0.000000 | **1-Year:** 0.000000 | **5-Year:** 0.000000 | **10-Year:** 0.000000 | **30-Year:** 0.000000

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000005449 | 7.60%                | 4.08%                | -3.00%               |
| Class ID C000005448 | 7.62%                | 4.12%                | -3.00%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-680700.98              | $52735559.06                               |
| Month 2  | $2285520.41              | $27788690.41                               |
| Month 3  | $2623538.98              | $-25287002.76                              |

### Schedule of Portfolio Investments

| Name                                            | Title                                              | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| N/A                                             | ELEMENT BIOSCIENCES SER C CVT PFD STOCK            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     38785 | NS      | $797291.61    | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | EIKON THERA SERIES B CVT PFD STOCK PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     45781 | NS      | $809800.62    | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | FLAME BIOSCIENCES INC PP                           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     37754 | NS      | $173290.86    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | HONOR TECHNOLOGY SER D CVT PFD PP                  | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    140829 | NS      | $323906.70    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | REFLEXION MEDICAL INC SR E CVT PFD PP              | CUSIP: TC9L8ZXJ6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     83857 | NS      | $198786.79    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | SIONNA THERAPEUTICS SR B CVT PFD STK PP            | CUSIP: TC9JBHH97<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     24459 | NS      | $238768.76    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | TEMPUS LAB SERIES E CVT PFD STOCK PP               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     37551 | NS      | $2269582.44   | 0.31%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | AFFINIVAX EXPENSE FUND PP                          | CUSIP: TC929D1E2<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       562 | NS      | $534.04       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | ARBOR BIO SERIES B CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     23994 | NS      | $397580.58    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Freenome Inc                                    | FREENOME HOLDINGS SER C CVT PFD PP                 | CUSIP: TC87S2BF1<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |     41732 | NS      | $487012.44    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | TESSERA THERAPEUTICS SR C CVT PFD STK PP           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     17475 | NS      | $357363.75    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Exact Sciences Corp                             | EXACT SCIENCES FDA MILESTONE PP                    | CUSIP: 000000000<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |     83712 | NS      | $44367.34     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | DELFI DIAGNOSTICS SR B CVT PFD STOCK PP            | CUSIP: TC7ZV25B2<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     84104 | NS      | $407530.98    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Gyroscope Therapeutics Ltd                      | GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 1 PP      | CUSIP: 000000000<br>LEI: 21380066POJ2YSHZAD73 | Long             | EC               | CORP              | US        |    253263 | NS      | $124098.87    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | INSCRIPTA SERIES E CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     64740 | NS      | $361249.20    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | TEMPUS LABS SERIES F CVT PFD STOCK PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      7944 | NS      | $486490.56    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | RING THERA SER B CVT PFD STOCK PP                  | CUSIP: TC7JBYSO7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     43885 | NS      | $403742.00    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | TEMPUS LAB SERIES G CVT PFD                        | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      5107 | NS      | $316531.86    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | PrognomIQ Series A-4 Pfd                           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     26885 | NS      | $82268.10     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | AFFINIVAX NEXT GEN PROD MILESTON EVNT PP           | CUSIP: TC7BEY6E7<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    331976 | NS      | $73034.68     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | REFLEXION MEDICAL INC CVT                          | CUSIP: TC70GKL85<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     51079 | NS      | $121085.07    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | VIVIDION THERAPEUTICS MILESTONE PAYMENT            | CUSIP: TC6TYXRT3<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    103855 | NS      | $46786.89     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Gyroscope Therapeutics Ltd                      | GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 3 PP      | CUSIP: 000000000<br>LEI: 21380066POJ2YSHZAD73 | Long             | EC               | CORP              | US        |    168785 | NS      | $43884.10     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PAX Labs Inc                                    | PAX LABS CLASS A COMMON PP                         | CUSIP: 000000000<br>LEI: 549300FKJA0AEKUHVG68 | Long             | EC               | CORP              | US        |    385684 | NS      | $254551.44    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | RING THERAPEUTICS SER C CVT PFD STK PP             | CUSIP: TC6IOH633<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     21482 | NS      | $197634.40    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | Ginkgo Bioworks Holdings Earn Out Shares $20.00 PP | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9683 | NS      | $4218.71      | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | CHROMA MEDICINE SERIES A CVT PFD STOCK P           | CUSIP: TC5E9TJR7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    235778 | NS      | $499849.36    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | GENERATE BIO SER B CVT PFD STOCK PP                | CUSIP: TC5CQ34B0<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     84485 | NS      | $1001147.25   | 0.14%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Freenome Inc                                    | FREENOME HOLDINGS SER D CVT PFD PP                 | CUSIP: 000000000<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |     23669 | NS      | $276217.23    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Exact Sciences Corp                             | - EXACT SCIENCES CMO MILESTONE PP                  | CUSIP: 000000000<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |    167424 | NS      | $88734.67     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | PROGNOMIQ SER B CVT PFD STOCK                      | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    168024 | NS      | $514153.44    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | FOG PHARMACEUTICALS SERIES C CVT PFD STOCK PP      | CUSIP: TC4W1BVL4<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     19483 | NS      | $209697.48    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Verily Life Sciences LLC                        | VERILY LIFE SCIENCES LLC SER B UNITS PP            | CUSIP: 000000000<br>LEI: 5493003ZYK1Z7M670M44 | Long             | EC               | CORP              | US        |      5220 | NS      | $786393.00    | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | COLOR HEALTH SERIES E CVT PFD STOCK PP             | CUSIP: TC4SC4HB5<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      1991 | NS      | $81431.90     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | LUMICKS TECH SER D CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |       221 | NS      | $427608.48    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | SALUDA MEDICAL WTS 1/23 PP                         | CUSIP: TC4G9B837<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9344 | NS      | $0.00         | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | ODYSSEY THERAPEUTICS SR B CVT PFD STK PP           | CUSIP: TC4CBMMO7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     50567 | NS      | $319373.08    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | SALIOGEN THERA SERIES B CVT PFD STOCK PP           | CUSIP: TC46G6E19<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      4690 | NS      | $496502.16    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | SALUDA MEDICAL SERIES D CVT PFD STOCK PP           | CUSIP: TC460A8T3<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     31146 | NS      | $397294.95    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | Series A-5 CVT Pfd                                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     23318 | NS      | $71353.08     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| DNA Script SAS                                  | DNA SCRIPT SERIES C CVT PFD STOCK PP               | CUSIP: TC3XW4UW2<br>LEI: 8945001SCRZOZAUEFH64 | Long             | EP               | CORP              | FR        |      1132 | NS      | $908812.05    | 0.12%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | NUTCRACKER THERA SER C CVT PFD STOCK PP            | CUSIP: TC3WVBUQ2<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     46567 | NS      | $500655.79    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | SCRIBE THERA SER B CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     45881 | NS      | $277639.70    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | COLOR HEALTH SERIES D-1 CVT PFD STOCK PP           | CUSIP: TC3KSMZE0<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     20165 | NS      | $824748.50    | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | INSITRO SER C CVT PFD PP                           | CUSIP: TC3HHHWL7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     26282 | NS      | $480726.69    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Freenome Inc                                    | FREENOME HOLDINGS SER B CVT PFD PP                 | CUSIP: 000000000<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |     71397 | NS      | $833202.99    | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | VIVIDION THERAPEUTICS MILESTONE PAYMENT            | CUSIP: TC3B3UJ15<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     77892 | NS      | $36967.36     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | TEMPUS LABS INC CVT PFD SR D PP                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     56856 | NS      | $3347681.28   | 0.46%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CLEAR LABS SERIES C CVT PFD PP                     | CUSIP: TC385IBS6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    171440 | NS      | $594948.23    | 0.08%             |  |  |  | Yes           |                  3 | On Loan: No      |
| REFLEXION MEDICAL INC                           | REFLEXION MEDICAL INC CVT PFD SR C PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    150708 | NS      | $357260.10    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | Acerta Future Payments PP                          | CUSIP: TC30M7746<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    826005 | NS      | $724406.68    | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | FOG PHARMA SER D CVT PFD STOCK PP                  | CUSIP: TC2VY7UZ1<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     27546 | NS      | $296480.35    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | HONOR TECHNOLOGY SER E CVT PFD STOCK PP            | CUSIP: TC2V4FT13<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     94916 | NS      | $218306.80    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CAPSULE CORP PP                                    | CUSIP: TC2P3HTV7<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     38140 | NS      | $111807.41    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Gyroscope Therapeutics Ltd                      | GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 2 PP      | CUSIP: 000000000<br>LEI: 21380066POJ2YSHZAD73 | Long             | EC               | CORP              | US        |    168785 | NS      | $45571.95     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Scholar Rock Holding Corp                       | SCHOLAR ROCK WTS 12.25 PP                          | CUSIP: TC2K72CM5<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |      6855 | NS      | $34769.55     | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | AFFINIVAX AFX3772 MILESTONE EVENT PP               | CUSIP: TC2HD0ET2<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    331976 | NS      | $199185.48    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | KARDIUM INC SER D-5 CVT PFD STOCK PP               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    403778 | NS      | $410173.84    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | TEMPUS LABS SERIES G-2 CVT PFD STOCK PP            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      5275 | NS      | $296507.75    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | Prime Medicine Restricted Common Stock             | CUSIP: TC21UGON5<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23411 | NS      | $413227.56    | 0.06%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | CHROMACODE INC SR D-2 CVT PFD STOCK PP             | CUSIP: TC1YLODP4<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    117322 | NS      | $76259.30     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | Ginkgo Bioworks Holdings Earn Out Shares $17.50 PP | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9683 | NS      | $4626.18      | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | NATIONAL RESILIENCE SER C CVT PFD STOCK            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     19224 | NS      | $1167473.52   | 0.16%             |  |  |  | Yes           |                  3 | On Loan: No      |
| SomaLogic Inc                                   | SOMALOGIC INC EARN OUT SHS $20 PP                  | CUSIP: TC1RC2ZS7<br>LEI: 549300D3W3Q8CN30YO25 | Long             | EC               | CORP              | US        |    174553 | NS      | $613.38       | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | DYNAMICS SPECIAL PURPOSE CORP                      | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5211 | NS      | $6980.13      | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | NATIONAL RESILIENCE SER B CVT PFD STOCK            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     54252 | NS      | $3294723.96   | 0.45%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | COLOR HEALTH SER D CVT PFD STOCK PP                | CUSIP: TC1HL9RU8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     13310 | NS      | $544379.00    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CLEERLY SER C CVT PFD STK PP                       | CUSIP: TC1A1CZJ4<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     26533 | NS      | $312574.66    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | INSITRO SER B CVT PFD PP                           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     39793 | NS      | $727857.74    | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | LARONDE SERIES B CVT PFD STOCK PP                  | CUSIP: TC14DLDG5<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     52537 | NS      | $294207.20    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CARIS LIFE SER D CVT PFD STOCK PP                  | CUSIP: TC13PNHL5<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    101939 | NS      | $670758.62    | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CELLANOME SERIES A CVT PFD STOCK PP                | CUSIP: TC13MXKE8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     89839 | NS      | $625279.44    | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Exact Sciences Corp                             | EXACT SCIENCES EXPENSE FUND PP                     | CUSIP: 000000000<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |       171 | NS      | $153.47       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CARIS LIFE SCIENCES SER C CVT PFD PP               | CUSIP: TC104V422<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    169277 | NS      | $1113842.66   | 0.15%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | Ginkgo Bioworks Holdings Earn Out Shares $15.00 PP | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9683 | NS      | $5117.11      | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| N/A                                             | TREELINE BIO SER A CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    106061 | NS      | $830192.48    | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | DELFI DIAGNOSTICS SR A CVT PFD STOCK PP            | CUSIP: TC0LOSSE0<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    154525 | NS      | $748760.16    | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | END EAVOR BIO SERIES B CVT PFD STOCK PP            | CUSIP: TC0KH48I6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     84304 | NS      | $397586.09    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | KARDIUM SERIES D6 CVT PFD STOCK PP                 | CUSIP: TC0GUUWU8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    556501 | NS      | $565315.98    | 0.08%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | CHROMACODE INC SR D-1 CVT PFD STOCK PP             | CUSIP: TC0GJI1L2<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    141298 | NS      | $91843.70     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | VIVIDION THERAPEUTICS MILESTONE PAYMENT 3          | CUSIP: TC09CIJA0<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     77892 | NS      | $33314.24     | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | GENESIS THERA SER A CVT PFD STOCK PP               | CUSIP: TC08XH789<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     37471 | NS      | $191386.88    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| N/A                                             | PROGNOMIQ SER C CVT PFD STOCK PP                   | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     51466 | NS      | $157485.96    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Novocure Ltd                                    | NOVOCURE LTD                                       | CUSIP: 000000000<br>LEI: 213800YPP55UMHWA4826 | Long             | EC               | CORP              | JE        |     52819 | NS      | $3874273.65   | 0.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Sophia Genetics SA                              | SOPHIA GENETICS SA                                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | CH        |     32820 | NS      | $67609.20     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Health Sciences Acquisitions Corp 2             | HEALTH SCIENCES ACQUISITIONS CORP 2                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |     30999 | NS      | $309680.01    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Royalty Pharma PLC                              | ROYALTY PHARMA PLC                                 | CUSIP: 000000000<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |     75254 | NS      | $2974038.08   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Wuxi Biologics Cayman Inc                       | WUXI BIOLOGICS CAYMAN INC                          | CUSIP: 000000000<br>LEI: 5493001TD2TH6VDTJU11 | Long             | EC               | CORP              | KY        |    135500 | NS      | $1026264.93   | 0.14%             |  |  |  | No            |                  2 | On Loan: No      |
| ADC Therapeutics SA                             | ADC THERAPEUTICS SA                                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | CH        |     55544 | NS      | $213288.96    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings plc                           | MEIRAGTX HOLDINGS PLC                              | CUSIP: 000000000<br>LEI: 54930007YV6NYIOGFZ57 | Long             | EC               | CORP              | KY        |      9836 | NS      | $64130.72     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| STERIS PLC                                      | STERIS PLC                                         | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | IE        |     10106 | NS      | $1866477.14   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| CRISPR Therapeutics AG                          | CRISPR THERAPEUTICS AG                             | CUSIP: 000000000<br>LEI: 506700O6IRRIQLT3W370 | Long             | EC               | CORP              | CH        |     11772 | NS      | $478531.80    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corp PLC                               | PROTHENA CORP PLC                                  | CUSIP: 000000000<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | IE        |     29190 | NS      | $1758697.50   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Daiichi Sankyo Co Ltd                           | DAIICHI SANKYO CO LTD                              | CUSIP: 000000000<br>LEI: 353800XGIU2IHQGC9504 | Long             | EC               | CORP              | JP        |    179300 | NS      | $5771073.59   | 0.79%             |  |  |  | No            |                  2 | On Loan: No      |
| Zimmer Biomet Holdings Inc                      | ZIMMER BIOMET HOLDINGS INC                         | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |     20065 | NS      | $2558287.50   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Zentalis Pharmaceuticals Inc                    | ZENTALIS PHARMACEUTICALS INC                       | CUSIP: 98943L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     26633 | NS      | $536388.62    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Zai Lab Ltd                                     | ZAI LAB LTD                                        | CUSIP: 98887Q104<br>LEI: 549300P2UYQ9U5LY1T58 | Long             | EC               | CORP              | KY        |     21226 | NS      | $651638.20    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor Inc                                      | XENCOR INC                                         | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |     34357 | NS      | $894656.28    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Inc                | WEST PHARMACEUTICAL SERVICES INC                   | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |     15645 | NS      | $3682050.75   | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corp                                     | WATERS CORP                                        | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |      3169 | NS      | $1085636.02   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Warby Parker Inc                                | WARBY PARKER INC                                   | CUSIP: 93403J106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     70171 | NS      | $946606.79    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Inc                      | VERTEX PHARMACEUTICALS INC                         | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |     56118 | NS      | $16205756.04  | 2.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                               | VEEVA SYSTEMS INC                                  | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |     26063 | NS      | $4206046.94   | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc                          | UNITEDHEALTH GROUP INC                             | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |    118657 | NS      | $62909568.26  | 8.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceutical Inc                   | ULTRAGENYX PHARMACEUTICAL INC                      | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |     59700 | NS      | $2765901.00   | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corp                           | TWIST BIOSCIENCE CORP                              | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |     14171 | NS      | $337411.51    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Theseus Pharmaceuticals Inc                     | THESEUS PHARMACEUTICALS INC                        | CUSIP: 88369M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     53475 | NS      | $266305.50    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc                    | THERMO FISHER SCIENTIFIC INC                       | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |     67786 | NS      | $37329072.34  | 5.12%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc                                | 10X GENOMICS INC                                   | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |     55854 | NS      | $2035319.76   | 0.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Tenaya Therapeutics Inc                         | TENAYA THERAPEUTICS INC                            | CUSIP: 87990A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     59906 | NS      | $120411.06    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Teleflex Inc                                    | TELEFLEX INC                                       | CUSIP: 879369106<br>LEI: UUL85LWXB4NGSWWXIQ25 | Long             | EC               | CORP              | US        |     14023 | NS      | $3500561.49   | 0.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Surgery Partners Inc                            | SURGERY PARTNERS INC                               | CUSIP: 86881A100<br>LEI: 549300LC82HG33S19I03 | Long             | EC               | CORP              | US        |     15196 | NS      | $423360.56    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Stryker Corp                                    | STRYKER CORP                                       | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |     67130 | NS      | $16412613.70  | 2.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc                          | STOKE THERAPEUTICS INC                             | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |     13995 | NS      | $129173.85    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| SpringWorks Therapeutics Inc                    | SPRINGWORKS THERAPEUTICS INC                       | CUSIP: 85205L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7848 | NS      | $204126.48    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| SomaLogic Inc                                   | SOMALOGIC INC                                      | CUSIP: 83444K113<br>LEI: 549300D3W3Q8CN30YO25 | Long             | EC               | CORP              | US        |      4962 | NS      | $1984.80      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Shockwave Medical Inc                           | SHOCKWAVE MEDICAL INC                              | CUSIP: 82489T104<br>LEI: 549300LDXO56IC5Y1538 | Long             | EC               | CORP              | US        |     25083 | NS      | $5157315.63   | 0.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Senti Biosciences Inc                           | SENTI BIOSCIENCES INC                              | CUSIP: 81726A100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     62666 | NS      | $88359.06     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Sema4 Holdings Corp                             | GENEDX HOLDINGS CORP                               | CUSIP: 81663L119<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11396 | NS      | $216.52       | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Sema4 Holdings Corp                             | GENEDX HOLDINGS CORP                               | CUSIP: 81663L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     63949 | NS      | $16869.75     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Seer Inc                                        | SEER INC                                           | CUSIP: 81578P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     44582 | NS      | $258575.60    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Seagen Inc                                      | SEAGEN INC                                         | CUSIP: 81181C104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     20296 | NS      | $2608238.96   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp                       | SCHOLAR ROCK HOLDING CORP                          | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |     87333 | NS      | $790363.65    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics Inc                        | SAREPTA THERAPEUTICS INC                           | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |     20610 | NS      | $2670643.80   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc                          | SANA BIOTECHNOLOGY INC                             | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     68347 | NS      | $269970.65    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Sage Therapeutics Inc                           | SAGE THERAPEUTICS INC                              | CUSIP: 78667J108<br>LEI: 5493000JX4BJS9W6CN35 | Long             | EC               | CORP              | US        |     24781 | NS      | $945147.34    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Rocket Pharmaceuticals Inc                      | ROCKET PHARMACEUTICALS INC                         | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |     21439 | NS      | $419561.23    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION Medicines Inc                        | REVOLUTION MEDICINES INC                           | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |     45509 | NS      | $1084024.38   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| T Rowe Price Government Reserve Investment Fund | T ROWE PRICE GOVERNMENT RESERVE INVESTMENT FUND    | CUSIP: 76105Y109<br>LEI: 5493007QR86JJLYO6D96 | Long             | STIV             | RF                | US        |   8274542 | NS      | $8274542.35   | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc                             | REPLIMUNE GROUP INC                                | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |     60833 | NS      | $1654657.60   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Repligen Corp                                   | REPLIGEN CORP                                      | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |      9497 | NS      | $1607937.07   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc                          | RELAY THERAPEUTICS INC                             | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49603 | NS      | $741068.82    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| REGENXBIO Inc                                   | REGENXBIO INC                                      | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |      5047 | NS      | $114465.96    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Regeneron Pharmaceuticals Inc                   | REGENERON PHARMACEUTICALS INC                      | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |     30656 | NS      | $22117997.44  | 3.03%             |  |  |  | No            |                  1 | On Loan: No      |
| RAPT Therapeutics Inc                           | RAPT THERAPEUTICS INC                              | CUSIP: 75382E109<br>LEI: 549300MB473BIU78ES48 | Long             | EC               | CORP              | US        |     32804 | NS      | $649519.20    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Rapid Micro Biosystems Inc                      | RAPID MICRO BIOSYSTEMS INC                         | CUSIP: 75340L104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     31688 | NS      | $35807.44     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Quanterix Corp                                  | QUANTERIX CORP                                     | CUSIP: 74766Q101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5554 | NS      | $76922.90     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                             | PROGENIC PHARMACEUTICALS CVR                       | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45500 | NS      | $52365.95     | 0.01%             |  |  |  | No            |                  3 | On Loan: No      |
| PROCEPT BioRobotics Corp                        | PROCEPT BIOROBOTICS CORP                           | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     30130 | NS      | $1251600.20   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Prelude Therapeutics Inc                        | PRELUDE THERAPEUTICS INC                           | CUSIP: 74065P101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10060 | NS      | $60762.40     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc                                      | PFIZER INC                                         | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |    320280 | NS      | $16411147.20  | 2.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Roche Holding AG                                | ROCHE HOLDING AG                                   | CUSIP: 000000000<br>LEI: 549300U41AUUVOAAOB37 | Long             | EC               | CORP              | CH        |     17640 | NS      | $5543150.48   | 0.76%             |  |  |  | No            |                  2 | On Loan: No      |
| Penumbra Inc                                    | PENUMBRA INC                                       | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |     30080 | NS      | $6691596.80   | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacific Biosciences of California Inc           | PACIFIC BIOSCIENCES OF CALIFORNIA INC              | CUSIP: 69404D108<br>LEI: 529900F1BWRE1M0KZN89 | Long             | EC               | CORP              | US        |    116774 | NS      | $955211.32    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| PTC Therapeutics Inc                            | PTC THERAPEUTICS INC                               | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |      9622 | NS      | $367271.74    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Option Care Health Inc                          | OPTION CARE HEALTH INC                             | CUSIP: 68404L201<br>LEI: 549300DI3Q5ACSYJRI17 | Long             | EC               | CORP              | US        |     28578 | NS      | $859912.02    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Olink Holding AB                                | OLINK HOLDING AB                                   | CUSIP: 680710100<br>LEI: 8945004Z7ZHV3LML4J27 | Long             | EC               | CORP              | SE        |     84134 | NS      | $2135320.92   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Oak Street Health Inc                           | OAK STREET HEALTH INC                              | CUSIP: 67181A107<br>LEI: 2549007CJE6GSEURLA30 | Long             | EC               | CORP              | US        |     22645 | NS      | $487093.95    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics Inc                          | NURIX THERAPEUTICS INC                             | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9696 | NS      | $106462.08    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Nevro Corp                                      | NEVRO CORP                                         | CUSIP: 64157F103<br>LEI: 254900SH91I4BOYKUE38 | Long             | EC               | CORP              | US        |      6863 | NS      | $271774.80    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc                      | NEUROCRINE BIOSCIENCES INC                         | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |     15372 | NS      | $1836031.68   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Morphic Holding Inc                             | MORPHIC HOLDING INC                                | CUSIP: 61775R105<br>LEI: 549300RWWOUFLHTY1224 | Long             | EC               | CORP              | US        |      8261 | NS      | $220981.75    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| MoonLake Immunotherapeutics                     | MOONLAKE IMMUNOTHERAPEUTICS                        | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |     39168 | NS      | $411264.00    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics Inc                     | MONTE ROSA THERAPEUTICS INC                        | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     60977 | NS      | $464034.97    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Molina Healthcare Inc                           | MOLINA HEALTHCARE INC                              | CUSIP: 60855R100<br>LEI: 549300NQQCEQ46YHZ591 | Long             | EC               | CORP              | US        |     34080 | NS      | $11253897.60  | 1.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                                     | MODERNA INC                                        | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |     46995 | NS      | $8441241.90   | 1.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirati Therapeutics Inc                         | MIRATI THERAPEUTICS INC                            | CUSIP: 60468T105<br>LEI: 529900GYRW59IDQV6N54 | Long             | EC               | CORP              | US        |     24497 | NS      | $1109959.07   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Mettler-Toledo International Inc                | METTLER-TOLEDO INTERNATIONAL INC                   | CUSIP: 592688105<br>LEI: 5493000BD5GJNUDIUG10 | Long             | EC               | CORP              | US        |      2248 | NS      | $3249371.60   | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Merck & Co Inc                                  | MERCK & CO INC                                     | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |    229661 | NS      | $25480887.95  | 3.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Sartorius AG                                    | SARTORIUS AG                                       | CUSIP: 000000000<br>LEI: 529900EQV2DY4FOAMU38 | Long             | EP               | CORP              | DE        |     10773 | NS      | $4253999.30   | 0.58%             |  |  |  | No            |                  2 | On Loan: No      |
| Evotec SE                                       | EVOTEC SE                                          | CUSIP: 000000000<br>LEI: 529900F9KI6OYITO9B12 | Long             | EC               | CORP              | DE        |     16684 | NS      | $271417.47    | 0.04%             |  |  |  | No            |                  2 | On Loan: No      |
| Lyell Immunopharma Inc                          | LYELL IMMUNOPHARMA INC                             | CUSIP: 55083R104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     74333 | NS      | $257935.51    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Longboard Pharmaceuticals Inc                   | LONGBOARD PHARMACEUTICALS INC                      | CUSIP: 54300N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23081 | NS      | $72935.96     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                                  | ELI LILLY & CO                                     | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |     88929 | NS      | $32533785.36  | 4.46%             |  |  |  | No            |                  1 | On Loan: No      |
| LianBio                                         | LIANBIO                                            | CUSIP: 53000N108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    102126 | NS      | $167486.64    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Lantheus Holdings Inc                           | LANTHEUS HOLDINGS INC                              | CUSIP: 516544103<br>LEI: 5299005HUB5IOJGO7S39 | Long             | EC               | CORP              | US        |      5978 | NS      | $304638.88    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc                         | KYMERA THERAPEUTICS INC                            | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     33447 | NS      | $834837.12    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Kronos Bio Inc                                  | KRONOS BIO INC                                     | CUSIP: 50107A104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5591 | NS      | $9057.42      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Kodiak Sciences Inc                             | KODIAK SCIENCES INC                                | CUSIP: 50015M109<br>LEI: 254900IXI5NI8C9OQE24 | Long             | EC               | CORP              | US        |     17662 | NS      | $126459.92    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Karuna Therapeutics Inc                         | KARUNA THERAPEUTICS INC                            | CUSIP: 48576A100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     27096 | NS      | $5324364.00   | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| IVERIC bio Inc                                  | IVERIC BIO INC                                     | CUSIP: 46583P102<br>LEI: 549300GZXI59U71XPM70 | Long             | EC               | CORP              | US        |     72315 | NS      | $1548264.15   | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics Inc                     | IOVANCE BIOTHERAPEUTICS INC COM                    | CUSIP: 462260100<br>LEI: 549300220Z2GHH33XL82 | Long             | EC               | CORP              | US        |     58312 | NS      | $372613.68    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals Inc                       | IONIS PHARMACEUTICALS INC                          | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |     51223 | NS      | $1934692.71   | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc                          | INTUITIVE SURGICAL INC                             | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |     81600 | NS      | $21652560.00  | 2.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Genmab A/S                                      | GENMAB A/S                                         | CUSIP: 000000000<br>LEI: 529900MTJPDPE4MHJ122 | Long             | EC               | CORP              | DK        |     14052 | NS      | $5941112.34   | 0.81%             |  |  |  | No            |                  2 | On Loan: No      |
| Intellia Therapeutics Inc                       | INTELLIA THERAPEUTICS INC                          | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |     18200 | NS      | $634998.00    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corp                                    | INSULET CORP                                       | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |     19343 | NS      | $5694385.77   | 0.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                                      | INSMED INC                                         | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    107941 | NS      | $2156661.18   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corp                                     | INCYTE CORP                                        | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |     39909 | NS      | $3205490.88   | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Inari Medical Inc                               | INARI MEDICAL INC                                  | CUSIP: 45332Y109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     17209 | NS      | $1093804.04   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunocore Holdings PLC                         | IMMUNOCORE HOLDINGS PLC                            | CUSIP: 45258D105<br>LEI: 213800IUE3DFS84BVN18 | Long             | EC               | CORP              | GB        |     47492 | NS      | $2710368.44   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Immuneering Corp                                | IMMUNEERING CORP                                   | CUSIP: 45254E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     76043 | NS      | $368808.55    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Ideaya Biosciences Inc                          | IDEAYA BIOSCIENCES INC                             | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |      7313 | NS      | $132877.21    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| iRhythm Technologies Inc                        | IRHYTHM TECHNOLOGIES INC                           | CUSIP: 450056106<br>LEI: 549300FJI72RJGDQS384 | Long             | EC               | CORP              | US        |      8146 | NS      | $763035.82    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| IGM Biosciences Inc                             | IGM BIOSCIENCES INC                                | CUSIP: 449585108<br>LEI: 5493008XCQES2N0VY969 | Long             | EC               | CORP              | US        |     13757 | NS      | $234006.57    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Humana Inc                                      | HUMANA INC                                         | CUSIP: 444859102<br>LEI: 529900YLDW34GJAO4J06 | Long             | EC               | CORP              | US        |     31534 | NS      | $16151399.46  | 2.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                                     | HOLOGIC INC                                        | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |     87854 | NS      | $6572357.74   | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| HCA Healthcare Inc                              | HCA HEALTHCARE INC                                 | CUSIP: 40412C101<br>LEI: 529900PH4ZGUH2MNEU89 | Long             | EC               | CORP              | US        |     26733 | NS      | $6414850.68   | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Guardant Health Inc                             | GUARDANT HEALTH INC                                | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |     49098 | NS      | $1335465.60   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Ginkgo Bioworks Holdings Inc                    | GINKGO BIOWORKS HOLDINGS INC                       | CUSIP: 37611X100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     91250 | NS      | $154212.50    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Generation Bio Co                               | GENERATION BIO CO                                  | CUSIP: 37148K100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     86363 | NS      | $339406.59    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| GE HealthCare Technologies Inc                  | GE HEALTHCARE TECHNOLOGIES INC                     | CUSIP: 36266G107<br>LEI: 549300OI9J7XOWZMUN85 | Long             | EC               | CORP              | US        |      7978 | NS      | $465755.64    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Fate Therapeutics Inc                           | FATE THERAPEUTICS INC                              | CUSIP: 31189P102<br>LEI: 549300L14Q4UHOODLA90 | Long             | EC               | CORP              | US        |     36150 | NS      | $364753.50    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| F-star Therapeutics Inc                         | F-STAR THERAPEUTICS INC                            | CUSIP: 30315R107<br>LEI: 5493003TRY5HK3M6WH76 | Long             | EC               | CORP              | US        |      2357 | NS      | $14896.24     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Exscientia Plc                                  | EXSCIENTIA LTD                                     | CUSIP: 30223G102<br>LEI: 213800XOQHH5CV85AD30 | Long             | EC               | CORP              | GB        |     10586 | NS      | $56423.38     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Exelixis Inc                                    | EXELIXIS INC                                       | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |     89392 | NS      | $1433847.68   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corp                             | EXACT SCIENCES CORP                                | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |     42754 | NS      | $2116750.54   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Entrada Therapeutics Inc                        | ENTRADA THERAPEUTICS INC                           | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     29975 | NS      | $405262.00    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Enanta Pharmaceuticals Inc                      | ENANTA PHARMACEUTICALS INC                         | CUSIP: 29251M106<br>LEI: 529900SSN4DODDQSN594 | Long             | EC               | CORP              | US        |      6200 | NS      | $288424.00    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Elanco Animal Health Inc                        | ELANCO ANIMAL HEALTH INC                           | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |     27562 | NS      | $336807.64    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| EQRx Inc                                        | EQRX INC                                           | CUSIP: 26886C115<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11096 | NS      | $2972.62      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| EQRx Inc                                        | EQRX INC                                           | CUSIP: 26886C107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     51453 | NS      | $126574.38    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                                    | DOXIMITY INC                                       | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     56349 | NS      | $1891072.44   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Dexcom Inc                                      | DEXCOM INC                                         | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |     51587 | NS      | $5841711.88   | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc                         | DENALI THERAPEUTICS INC                            | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |     47783 | NS      | $1328845.23   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc                  | DAY ONE BIOPHARMACEUTICALS INC                     | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     21830 | NS      | $469781.60    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Danaher Corp                                    | DANAHER CORP                                       | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |    103489 | NS      | $27468050.38  | 3.77%             |  |  |  | No            |                  1 | On Loan: No      |
| DICE Therapeutics Inc                           | DICE THERAPEUTICS INC                              | CUSIP: 23345J104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     30180 | NS      | $941616.00    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                                | CYTOKINETICS INC                                   | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |     16059 | NS      | $735823.38    | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Cooper Cos Inc/The                              | COOPER COS INC/THE                                 | CUSIP: 216648402<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |      4875 | NS      | $1612016.25   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Certara Inc                                     | CERTARA INC                                        | CUSIP: 15687V109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     21846 | NS      | $351065.22    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Cerevel Therapeutics Holdings Inc               | CEREVEL THERAPEUTICS HOLDINGS INC                  | CUSIP: 15678U128<br>LEI: 254900RJNIRS9COSQR41 | Long             | EC               | CORP              | US        |     73121 | NS      | $2306236.34   | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Centessa Pharmaceuticals PLC                    | CENTESSA PHARMACEUTICALS PLC                       | CUSIP: 152309100<br>LEI: 213800GIDAARDSKOI827 | Long             | EC               | CORP              | GB        |     46861 | NS      | $145269.10    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Centene Corp                                    | CENTENE CORP                                       | CUSIP: 15135B101<br>LEI: 549300Z7JJ4TQSQGT333 | Long             | EC               | CORP              | US        |    149975 | NS      | $12299449.75  | 1.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc                        | CELLDEX THERAPEUTICS INC                           | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |     28247 | NS      | $1258968.79   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalent Inc                                    | CATALENT INC                                       | CUSIP: 148806102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     43141 | NS      | $1941776.41   | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Cigna Corp                                      | CIGNA CORP                                         | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |     31945 | NS      | $10584656.30  | 1.45%             |  |  |  | No            |                  1 | On Loan: No      |
| C4 Therapeutics Inc                             | C4 THERAPEUTICS INC                                | CUSIP: 12529R107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     21403 | NS      | $126277.70    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Burning Rock Biotech Ltd                        | BURNING ROCK BIOTECH LTD                           | CUSIP: 12233L107<br>LEI: 5493006HO04GB8AQ2V43 | Long             | EC               | CORP              | KY        |     10102 | NS      | $22729.50     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Bruker Corp                                     | BRUKER CORP                                        | CUSIP: 116794108<br>LEI: LEBZ6VLQ6I8XB1NHVY15 | Long             | EC               | CORP              | US        |     83753 | NS      | $5724517.55   | 0.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Blueprint Medicines Corp                        | BLUEPRINT MEDICINES CORP                           | CUSIP: 09627Y109<br>LEI: 5299004CC60O9T5HVM83 | Long             | EC               | CORP              | US        |     50538 | NS      | $2214069.78   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| BioNTech SE                                     | BIONTECH SE                                        | CUSIP: 09075V102<br>LEI: 894500UZJ5LG1F8J1U58 | Long             | EC               | CORP              | DE        |     25714 | NS      | $3862757.08   | 0.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Techne Corp                                 | BIO-TECHNE CORP                                    | CUSIP: 09073M104<br>LEI: 54930073RLKQ51TILZ35 | Long             | EC               | CORP              | US        |     19617 | NS      | $1625856.96   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                                      | BIOGEN INC                                         | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |     16091 | NS      | $4455919.72   | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicycle Therapeutics PLC                        | BICYCLE THERAPEUTICS PLC                           | CUSIP: 088786108<br>LEI: 213800XKUI6R7GKC3E43 | Long             | EC               | CORP              | GB        |     12072 | NS      | $357331.20    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| BeiGene Ltd                                     | BEIGENE LTD                                        | CUSIP: 07725L102<br>LEI: 549300JFUK6FRD5MH739 | Long             | EC               | CORP              | KY        |      7778 | NS      | $1710693.32   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton Dickinson and Co                         | BECTON DICKINSON AND CO                            | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |     51088 | NS      | $12991678.40  | 1.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Avidity Biosciences Inc                         | AVIDITY BIOSCIENCES INC                            | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     77173 | NS      | $1712468.87   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Avantor Inc                                     | AVANTOR INC                                        | CUSIP: 05352A100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    189076 | NS      | $3987612.84   | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| AstraZeneca PLC                                 | ASTRAZENECA PLC                                    | CUSIP: 046353108<br>LEI: PY6ZZQWO2IZFZC3IOL08 | Long             | EC               | CORP              | GB        |    359982 | NS      | $24406779.60  | 3.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Ascendis Pharma A/S                             | ASCENDIS PHARMA A/S                                | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |     37605 | NS      | $4592698.65   | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                                     | ARVINAS INC                                        | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23413 | NS      | $800958.73    | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Argenx SE                                       | ARGENX SE                                          | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |     31663 | NS      | $11994894.29  | 1.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals Inc                     | APELLIS PHARMACEUTICALS INC                        | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |     28475 | NS      | $1472442.25   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Elevance Health Inc                             | ELEVANCE HEALTH INC                                | CUSIP: 036752103<br>LEI: 8MYN82XMYQH89CTMTH67 | Long             | EC               | CORP              | US        |     44616 | NS      | $22886669.52  | 3.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc                     | ALNYLAM PHARMACEUTICALS INC                        | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |     68901 | NS      | $16374322.65  | 2.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Allogene Therapeutics Inc                       | ALLOGENE THERAPEUTICS INC                          | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     85113 | NS      | $535360.77    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Allakos Inc                                     | ALLAKOS INC                                        | CUSIP: 01671P100<br>LEI: 549300S6ZD1W6BPMDY37 | Long             | EC               | CORP              | US        |     24100 | NS      | $202922.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Alignment Healthcare Inc                        | ALIGNMENT HEALTHCARE INC                           | CUSIP: 01625V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     57752 | NS      | $679163.52    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Alector Inc                                     | ALECTOR INC                                        | CUSIP: 014442107<br>LEI: 549300Z8RQOIY1JMHC25 | Long             | EC               | CORP              | US        |     16082 | NS      | $148436.86    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| agilon health Inc                               | AGILON HEALTH INC                                  | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     21898 | NS      | $353433.72    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Agios Pharmaceuticals Inc                       | AGIOS PHARMACEUTICALS INC                          | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     18862 | NS      | $529644.96    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc                        | AGILENT TECHNOLOGIES INC                           | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |     97335 | NS      | $14566182.75  | 2.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp                   | ADAPTIVE BIOTECHNOLOGIES CORP                      | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |     27974 | NS      | $213721.36    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Invivyd Inc                                     | INVIVYD INC                                        | CUSIP: 00534A102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     15900 | NS      | $23850.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ACADIA Pharmaceuticals Inc                      | ACADIA PHARMACEUTICALS INC                         | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |     52982 | NS      | $843473.44    | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc                                      | ABBVIE INC                                         | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |     76334 | NS      | $12336337.74  | 1.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Aadi Bioscience Inc                             | AADI BIOSCIENCE INC                                | CUSIP: 00032Q104<br>LEI: 549300G3U7TKW1M58L09 | Long             | EC               | CORP              | US        |      6782 | NS      | $87013.06     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2022-12-31

**Name of Applicant:** T. ROWE PRICE EQUITY SERIES, INC.

**Signature:** /s/ Alan Dupski

**Name of Signer:** Alan Dupski

**Title:** Treasurer & Vice President