# EDGAR Filing Document

**Accession Number:** 0001123274
**File Stem:** 0001123274-23-000002
**Filing Date:** 2023-2
**Character Count:** 19435
**Document Hash:** 90884655fba5e857898c5cd294e0f770
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001123274-23-000002.hdr.sgml**: 20230208

**ACCESSION NUMBER**: 0001123274-23-000002

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230208

**DATE AS OF CHANGE**: 20230208

**EFFECTIVENESS DATE**: 20230208

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Pictet & Cie (Europe) SA
- **CENTRAL INDEX KEY:** 0001123274
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** N4
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-15846
- **FILM NUMBER:** 23597742

**BUSINESS ADDRESS:**
- **STREET 1:** 15A, AVENUE J. F. KENNEDY
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** 1855
- **BUSINESS PHONE:** 00352467171

**MAIL ADDRESS:**
- **STREET 1:** 15A, AVENUE J. F. KENNEDY
- **CITY:** LUXEMBOURG
- **STATE:** N4
- **ZIP:** 1855

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PICTET & CIE EUROPE SA
- **DATE OF NAME CHANGE:** 20030129

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PICKET & CIE EUROPE SA
- **DATE OF NAME CHANGE:** 20000905

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2022

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** Pictet  Cie (Europe) SA<br>**Address:** 15A AVENUE J. F. KENNEDY<br>LUXEMBOURG, N4 1855

**Form 13F File Number:** 028-15846

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Antoine Favre<br>**Title:** Head of Compliance<br>**Phone:** 003524671717189

**Signature, Place, and Date of Signing:**

Antoine Favre  Luxembourg, N4  02-08-2023<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 162

**Form 13F Information Table Value Total:** $2045960369

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 10X GENOMICS INC | CL A COM | 88025U109 |  | 244695 | 6715 | SH |  | SOLE |  | 0 | 0 | 6715 |
| 3M CO | COM | 88579Y101 |  | 7930310 | 66130 | SH |  | SOLE |  | 0 | 0 | 66130 |
| ABBOTT LABS | COM | 002824100 |  | 4257876 | 38782 | SH |  | SOLE |  | 0 | 0 | 38782 |
| ABBVIE INC | COM | 00287Y109 |  | 14148632 | 87548 | SH |  | SOLE |  | 0 | 0 | 87548 |
| ACCENTURE PLC IRELAND | SHS CLASS A | G1151C101 |  | 306599 | 1149 | SH |  | SOLE |  | 0 | 0 | 1149 |
| ADOBE SYSTEMS INCORPORATED | COM | 00724F101 |  | 5784614 | 17189 | SH |  | SOLE |  | 0 | 0 | 17189 |
| ADVANCED MICRO DEVICES INC | COM | 007903107 |  | 9237886 | 142626 | SH |  | SOLE |  | 0 | 0 | 142626 |
| AIR PRODS  CHEMS INC | COM | 009158106 |  | 1700362 | 5516 | SH |  | SOLE |  | 0 | 0 | 5516 |
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 |  | 1676969 | 19037 | SH |  | SOLE |  | 0 | 0 | 19037 |
| ALIGN TECHNOLOGY INC | COM | 016255101 |  | 16263764 | 77116 | SH |  | SOLE |  | 0 | 0 | 77116 |
| ALPHABET INC | CAP STK CL A | 02079K305 |  | 131814473 | 1493987 | SH |  | SOLE |  | 0 | 0 | 1493987 |
| ALPHABET INC | CAP STK CL C | 02079K107 |  | 43983905 | 495705 | SH |  | SOLE |  | 0 | 0 | 495705 |
| AMAZON COM INC | COM | 023135106 |  | 127481508 | 1517637 | SH |  | SOLE |  | 0 | 0 | 1517637 |
| AMEDISYS INC | COM | 023436108 |  | 823955 | 9863 | SH |  | SOLE |  | 0 | 0 | 9863 |
| AMETEK INC | COM | 031100100 |  | 4831937 | 34583 | SH |  | SOLE |  | 0 | 0 | 34583 |
| AON PLC | SHS CL A | G0403H108 |  | 4602047 | 15333 | SH |  | SOLE |  | 0 | 0 | 15333 |
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 |  | 375518 | 7262 | SH |  | SOLE |  | 0 | 0 | 7262 |
| APPLE INC | COM | 037833100 |  | 36220846 | 278772 | SH |  | SOLE |  | 0 | 0 | 278772 |
| ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 |  | 384833 | 9488 | SH |  | SOLE |  | 0 | 0 | 9488 |
| AUTODESK INC | COM | 052769106 |  | 2045105 | 10944 | SH |  | SOLE |  | 0 | 0 | 10944 |
| BAIDU INC | SPON ADR REP A | 056752108 |  | 1009861 | 8829 | SH |  | SOLE |  | 0 | 0 | 8829 |
| BANK AMERICA CORP | COM | 060505104 |  | 5691672 | 171850 | SH |  | SOLE |  | 0 | 0 | 171850 |
| BAXTER INTL INC | COM | 071813109 |  | 6965968 | 136668 | SH |  | SOLE |  | 0 | 0 | 136668 |
| BECTON DICKINSON  CO | COM | 075887109 |  | 1017200 | 4000 | SH |  | SOLE |  | 0 | 0 | 4000 |
| BERKSHIRE HATHAWAY INC DEL | CL A | 084670108 |  | 44527545 | 95 | SH |  | SOLE |  | 0 | 0 | 95 |
| BERKSHIRE HATHAWAY INC DEL | CL B NEW | 084670702 |  | 11366902 | 36798 | SH |  | SOLE |  | 0 | 0 | 36798 |
| BIOGEN INC | COM | 09062X103 |  | 1068911 | 3860 | SH |  | SOLE |  | 0 | 0 | 3860 |
| BIONTECH SE | SPONSORED ADS | 09075V102 |  | 226081 | 1505 | SH |  | SOLE |  | 0 | 0 | 1505 |
| BOOKING HOLDINGS INC | COM | 09857L108 |  | 8250556 | 4094 | SH |  | SOLE |  | 0 | 0 | 4094 |
| BOSTON SCIENTIFIC CORP | COM | 101137107 |  | 865943 | 18715 | SH |  | SOLE |  | 0 | 0 | 18715 |
| BRISTOL-MYERS SQUIBB CO | COM | 110122108 |  | 809438 | 11250 | SH |  | SOLE |  | 0 | 0 | 11250 |
| CAMECO CORP | COM | 13321L108 |  | 20385496 | 900000 | SH |  | SOLE |  | 0 | 0 | 900000 |
| CASTLE BIOSCIENCES INC | COM | 14843C105 |  | 297028 | 12618 | SH |  | SOLE |  | 0 | 0 | 12618 |
| CHEVRON CORP NEW | COM | 166764100 |  | 16186767 | 90182 | SH |  | SOLE |  | 0 | 0 | 90182 |
| CHIPOTLE MEXICAN GRILL INC | COM | 169656105 |  | 28354746 | 20436 | SH |  | SOLE |  | 0 | 0 | 20436 |
| CINTAS CORP | COM | 172908105 |  | 56678762 | 125501 | SH |  | SOLE |  | 0 | 0 | 125501 |
| CME GROUP INC | COM | 12572Q105 |  | 3218582 | 19140 | SH |  | SOLE |  | 0 | 0 | 19140 |
| COCA COLA CO | COM | 191216100 |  | 1911481 | 30050 | SH |  | SOLE |  | 0 | 0 | 30050 |
| COLGATE PALMOLIVE CO | COM | 194162103 |  | 25693183 | 326097 | SH |  | SOLE |  | 0 | 0 | 326097 |
| CONSTELLATION BRANDS INC | CL A | 21036P108 |  | 1053999 | 4548 | SH |  | SOLE |  | 0 | 0 | 4548 |
| COSTCO WHSL CORP NEW | COM | 22160K105 |  | 41769750 | 91500 | SH |  | SOLE |  | 0 | 0 | 91500 |
| DANAHER CORPORATION | COM | 235851102 |  | 72711544 | 273949 | SH |  | SOLE |  | 0 | 0 | 273949 |
| DAVITA INC | COM | 23918K108 |  | 224010 | 3000 | SH |  | SOLE |  | 0 | 0 | 3000 |
| DEUTSCHE BANK A G | NAMEN AKT | D18190898 |  | 185321 | 16400 | SH |  | SOLE |  | 0 | 0 | 16400 |
| DEXCOM INC | COM | 252131107 |  | 452281 | 3994 | SH |  | SOLE |  | 0 | 0 | 3994 |
| DISNEY WALT CO | COM | 254687106 |  | 10305445 | 118617 | SH |  | SOLE |  | 0 | 0 | 118617 |
| DROPBOX INC | CL A | 26210C104 |  | 814968 | 36415 | SH |  | SOLE |  | 0 | 0 | 36415 |
| ECOLAB INC | COM | 278865100 |  | 361280 | 2482 | SH |  | SOLE |  | 0 | 0 | 2482 |
| EDWARDS LIFESCIENCES CORP | COM | 28176E108 |  | 611354 | 8194 | SH |  | SOLE |  | 0 | 0 | 8194 |
| ELECTRONIC ARTS INC | COM | 285512109 |  | 9569260 | 78321 | SH |  | SOLE |  | 0 | 0 | 78321 |
| EOG RES INC | COM | 26875P101 |  | 4341640 | 33521 | SH |  | SOLE |  | 0 | 0 | 33521 |
| ERMENEGILDO ZEGNA N V | ORD SHS | N30577105 |  | 238716 | 22800 | SH |  | SOLE |  | 0 | 0 | 22800 |
| ETSY INC | COM | 29786A106 |  | 476605 | 3979 | SH |  | SOLE |  | 0 | 0 | 3979 |
| EXACT SCIENCES CORP | COM | 30063P105 |  | 7098150 | 143368 | SH |  | SOLE |  | 0 | 0 | 143368 |
| EXXON MOBIL CORP | COM | 30231G102 |  | 267478 | 2425 | SH |  | SOLE |  | 0 | 0 | 2425 |
| FIDELITY NATL INFORMATION SV | COM | 31620M106 |  | 2998902 | 44199 | SH |  | SOLE |  | 0 | 0 | 44199 |
| GILEAD SCIENCES INC | COM | 375558103 |  | 1375746 | 16025 | SH |  | SOLE |  | 0 | 0 | 16025 |
| GLOBAL BLUE GROUP HOLDING AG | ORD SHS | H33700107 |  | 595284 | 128571 | SH |  | SOLE |  | 0 | 0 | 128571 |
| GLOBAL X FDS | RBTCS ARTFL INTE | 37954Y715 |  | 401239 | 19525 | SH |  | SOLE |  | 0 | 0 | 19525 |
| GLOBUS MED INC | CL A | 379577208 |  | 1535012 | 20668 | SH |  | SOLE |  | 0 | 0 | 20668 |
| GOLDMAN SACHS GROUP INC | COM | 38141G104 |  | 504769 | 1470 | SH |  | SOLE |  | 0 | 0 | 1470 |
| HCA HEALTHCARE INC | COM | 40412C101 |  | 337384 | 1406 | SH |  | SOLE |  | 0 | 0 | 1406 |
| HDFC BANK LTD | SPONSORED ADS | 40415F101 |  | 2495802 | 36483 | SH |  | SOLE |  | 0 | 0 | 36483 |
| HOME DEPOT INC | COM | 437076102 |  | 1656370 | 5244 | SH |  | SOLE |  | 0 | 0 | 5244 |
| HONEYWELL INTL INC | COM | 438516106 |  | 16227439 | 75723 | SH |  | SOLE |  | 0 | 0 | 75723 |
| ICON PLC | SHS | G4705A100 |  | 421523 | 2170 | SH |  | SOLE |  | 0 | 0 | 2170 |
| IDEXX LABS INC | COM | 45168D104 |  | 36778410 | 90152 | SH |  | SOLE |  | 0 | 0 | 90152 |
| ILLUMINA INC | COM | 452327109 |  | 1302168 | 6440 | SH |  | SOLE |  | 0 | 0 | 6440 |
| INFOSYS LTD | SPONSORED ADR | 456788108 |  | 2106161 | 116944 | SH |  | SOLE |  | 0 | 0 | 116944 |
| INSULET CORP | COM | 45784P101 |  | 448062 | 1522 | SH |  | SOLE |  | 0 | 0 | 1522 |
| INTEL CORP | COM | 458140100 |  | 430809 | 16300 | SH |  | SOLE |  | 0 | 0 | 16300 |
| INTERCONTINENTAL EXCHANGE IN | COM | 45866F104 |  | 6102053 | 59480 | SH |  | SOLE |  | 0 | 0 | 59480 |
| INTERNATIONAL BUSINESS MACHS | COM | 459200101 |  | 825615 | 5860 | SH |  | SOLE |  | 0 | 0 | 5860 |
| INTERNATIONAL FLAVORS | COM | 459506101 |  | 540974 | 5160 | SH |  | SOLE |  | 0 | 0 | 5160 |
| INTUITIVE SURGICAL INC | COM NEW | 46120E602 |  | 48637328 | 183295 | SH |  | SOLE |  | 0 | 0 | 183295 |
| INVESCO QQQ TR | UNIT SER 1 | 46090E103 |  | 20440718 | 76764 | SH |  | SOLE |  | 0 | 0 | 76764 |
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 |  | 179470 | 28086 | SH |  | SOLE |  | 0 | 0 | 28086 |
| IRHYTHM TECHNOLOGIES INC | COM | 450056106 |  | 317635 | 3391 | SH |  | SOLE |  | 0 | 0 | 3391 |
| ISHARES INC | MSCI JPN ETF NEW | 46434G822 |  | 230336 | 4231 | SH |  | SOLE |  | 0 | 0 | 4231 |
| ISHARES INC | MSCI WORLD ETF | 464286392 |  | 322943 | 2956 | SH |  | SOLE |  | 0 | 0 | 2956 |
| ISHARES TR | CORE US AGGBD ET | 464287226 |  | 321231 | 3312 | SH |  | SOLE |  | 0 | 0 | 3312 |
| ISHARES TR | S 500 VAL ETF | 464287408 |  | 17319907 | 119390 | SH |  | SOLE |  | 0 | 0 | 119390 |
| ISHARES TR | CORE S ETF | 464287200 |  | 13481929 | 35090 | SH |  | SOLE |  | 0 | 0 | 35090 |
| ISHARES TR | RUS 1000 VAL ETF | 464287598 |  | 5137144 | 33875 | SH |  | SOLE |  | 0 | 0 | 33875 |
| ISHARES TR | MSCI USA MIN VOL | 46429B697 |  | 3384014 | 46935 | SH |  | SOLE |  | 0 | 0 | 46935 |
| ISHARES TR | MSCI INDIA ETF | 46429B598 |  | 407967 | 9774 | SH |  | SOLE |  | 0 | 0 | 9774 |
| ISHARES TR | IBOXX INV CP ETF | 464287242 |  | 241540 | 2291 | SH |  | SOLE |  | 0 | 0 | 2291 |
| JOHNSON  JOHNSON | COM | 478160104 |  | 4384453 | 24820 | SH |  | SOLE |  | 0 | 0 | 24820 |
| JOHNSON CTLS INTL PLC | SHS | G51502105 |  | 4233984 | 66156 | SH |  | SOLE |  | 0 | 0 | 66156 |
| JPMORGAN CHASE  CO | COM | 46625H100 |  | 28376901 | 211610 | SH |  | SOLE |  | 0 | 0 | 211610 |
| LAUDER ESTEE COS INC | CL A | 518439104 |  | 6861978 | 27657 | SH |  | SOLE |  | 0 | 0 | 27657 |
| LILLY ELI  CO | COM | 532457108 |  | 1074838 | 2938 | SH |  | SOLE |  | 0 | 0 | 2938 |
| LINDE PLC | SHS | G5494J103 |  | 14989121 | 45980 | SH |  | SOLE |  | 0 | 0 | 45980 |
| LOCKHEED MARTIN CORP | COM | 539830109 |  | 778384 | 1600 | SH |  | SOLE |  | 0 | 0 | 1600 |
| LOGITECH INTL S A | SHS | H50430232 |  | 958051 | 15534 | SH |  | SOLE |  | 0 | 0 | 15534 |
| LYONDELLBASELL INDUSTRIES N | SHS - A - | N53745100 |  | 1851403 | 22298 | SH |  | SOLE |  | 0 | 0 | 22298 |
| MASTERCARD INCORPORATED | CL A | 57636Q104 |  | 16419115 | 47218 | SH |  | SOLE |  | 0 | 0 | 47218 |
| MCDONALDS CORP | COM | 580135101 |  | 60755787 | 230546 | SH |  | SOLE |  | 0 | 0 | 230546 |
| MEDTRONIC PLC | SHS | G5960L103 |  | 15511979 | 199588 | SH |  | SOLE |  | 0 | 0 | 199588 |
| MERCK  CO INC | COM | 58933Y105 |  | 17866389 | 161031 | SH |  | SOLE |  | 0 | 0 | 161031 |
| META PLATFORMS INC | CL A | 30303M102 |  | 19047656 | 158282 | SH |  | SOLE |  | 0 | 0 | 158282 |
| MICRON TECHNOLOGY INC | COM | 595112103 |  | 2291983 | 45858 | SH |  | SOLE |  | 0 | 0 | 45858 |
| MICROSOFT CORP | COM | 594918104 |  | 149166361 | 621993 | SH |  | SOLE |  | 0 | 0 | 621993 |
| MODERNA INC | COM | 60770K107 |  | 26087290 | 145236 | SH |  | SOLE |  | 0 | 0 | 145236 |
| MONDELEZ INTL INC | CL A | 609207105 |  | 17688177 | 265389 | SH |  | SOLE |  | 0 | 0 | 265389 |
| MOODYS CORP | COM | 615369105 |  | 10792067 | 38734 | SH |  | SOLE |  | 0 | 0 | 38734 |
| NATERA INC | COM | 632307104 |  | 441026 | 10979 | SH |  | SOLE |  | 0 | 0 | 10979 |
| NEOGEN CORP | COM | 640491106 |  | 1028787 | 67550 | SH |  | SOLE |  | 0 | 0 | 67550 |
| NETFLIX INC | COM | 64110L106 |  | 423153 | 1435 | SH |  | SOLE |  | 0 | 0 | 1435 |
| NIKE INC | CL B | 654106103 |  | 23470919 | 200589 | SH |  | SOLE |  | 0 | 0 | 200589 |
| NOVAGOLD RES INC | COM NEW | 66987E206 |  | 23883084 | 4000000 | SH |  | SOLE |  | 0 | 0 | 4000000 |
| NUTRIEN LTD | COM | 67077M108 |  | 1904141 | 26100 | SH |  | SOLE |  | 0 | 0 | 26100 |
| NVIDIA CORPORATION | COM | 67066G104 |  | 22565477 | 154410 | SH |  | SOLE |  | 0 | 0 | 154410 |
| ORACLE CORP | COM | 68389X105 |  | 280613 | 3433 | SH |  | SOLE |  | 0 | 0 | 3433 |
| OTIS WORLDWIDE CORP | COM | 68902V107 |  | 5197905 | 66376 | SH |  | SOLE |  | 0 | 0 | 66376 |
| PALO ALTO NETWORKS INC | COM | 697435105 |  | 2315108 | 16591 | SH |  | SOLE |  | 0 | 0 | 16591 |
| PAYPAL HLDGS INC | COM | 70450Y103 |  | 2642761 | 37107 | SH |  | SOLE |  | 0 | 0 | 37107 |
| PEPSICO INC | COM | 713448108 |  | 45367339 | 251120 | SH |  | SOLE |  | 0 | 0 | 251120 |
| PERRIGO CO PLC | SHS | G97822103 |  | 294879 | 8650 | SH |  | SOLE |  | 0 | 0 | 8650 |
| PFIZER INC | COM | 717081103 |  | 3440100 | 67137 | SH |  | SOLE |  | 0 | 0 | 67137 |
| PROCTER AND GAMBLE CO | COM | 742718109 |  | 11284097 | 74453 | SH |  | SOLE |  | 0 | 0 | 74453 |
| PURE STORAGE INC | CL A | 74624M102 |  | 257217 | 9612 | SH |  | SOLE |  | 0 | 0 | 9612 |
| REPLIGEN CORP | COM | 759916109 |  | 370620 | 2189 | SH |  | SOLE |  | 0 | 0 | 2189 |
| ROLLINS INC | COM | 775711104 |  | 1943928 | 53200 | SH |  | SOLE |  | 0 | 0 | 53200 |
| ROYALTY PHARMA PLC | SHS CLASS A | G7709Q104 |  | 1976000 | 50000 | SH |  | SOLE |  | 0 | 0 | 50000 |
| SALESFORCE INC | COM | 79466L302 |  | 12847706 | 96898 | SH |  | SOLE |  | 0 | 0 | 96898 |
| SCHLUMBERGER LTD | COM STK | 806857108 |  | 606771 | 11350 | SH |  | SOLE |  | 0 | 0 | 11350 |
| SEA LTD | SPONSORD ADS | 81141R100 |  | 830815 | 15968 | SH |  | SOLE |  | 0 | 0 | 15968 |
| SEAGEN INC | COM | 81181C104 |  | 339780 | 2644 | SH |  | SOLE |  | 0 | 0 | 2644 |
| SHELL PLC | SPON ADS | 780259305 |  | 415735 | 7300 | SH |  | SOLE |  | 0 | 0 | 7300 |
| SNOWFLAKE INC | CL A | 833445109 |  | 2318171 | 16150 | SH |  | SOLE |  | 0 | 0 | 16150 |
| SOPHIA GENETICS SA | ORDINARY SHARES | H82027105 |  | 468856 | 227600 | SH |  | SOLE |  | 0 | 0 | 227600 |
| SPDR GOLD TR | GOLD SHS | 78463V107 |  | 7586979 | 44724 | SH |  | SOLE |  | 0 | 0 | 44724 |
| SPDR S 500 ETF TR | TR UNIT | 78462F103 |  | 11687061 | 30560 | SH |  | SOLE |  | 0 | 0 | 30560 |
| SPDR SER TR | S BIOTECH | 78464A870 |  | 329842 | 3974 | SH |  | SOLE |  | 0 | 0 | 3974 |
| STARBUCKS CORP | COM | 855244109 |  | 4186934 | 42207 | SH |  | SOLE |  | 0 | 0 | 42207 |
| STRYKER CORPORATION | COM | 863667101 |  | 621249 | 2541 | SH |  | SOLE |  | 0 | 0 | 2541 |
| TAIWAN SEMICONDUCTOR MFG LTD | SPONSORED ADS | 874039100 |  | 10660711 | 143116 | SH |  | SOLE |  | 0 | 0 | 143116 |
| TESLA INC | COM | 88160R101 |  | 1728831 | 14035 | SH |  | SOLE |  | 0 | 0 | 14035 |
| TEXAS INSTRS INC | COM | 882508104 |  | 8025066 | 48572 | SH |  | SOLE |  | 0 | 0 | 48572 |
| THERMO FISHER SCIENTIFIC INC | COM | 883556102 |  | 81079741 | 147233 | SH |  | SOLE |  | 0 | 0 | 147233 |
| TJX COS INC NEW | COM | 872540109 |  | 705972 | 8869 | SH |  | SOLE |  | 0 | 0 | 8869 |
| TRANE TECHNOLOGIES PLC | SHS | G8994E103 |  | 248269 | 1477 | SH |  | SOLE |  | 0 | 0 | 1477 |
| UBS GROUP AG | SHS | H42097107 |  | 216945 | 11666 | SH |  | SOLE |  | 0 | 0 | 11666 |
| UNIQURE NV | SHS | N90064101 |  | 276393 | 12192 | SH |  | SOLE |  | 0 | 0 | 12192 |
| UNITEDHEALTH GROUP INC | COM | 91324P102 |  | 104664955 | 197414 | SH |  | SOLE |  | 0 | 0 | 197414 |
| VANECK ETF TRUST | OIL SERVICES ETF | 92189H607 |  | 44999400 | 148000 | SH |  | SOLE |  | 0 | 0 | 148000 |
| VANGUARD INDEX FDS | S 500 ETF SHS | 922908363 |  | 5510768 | 15685 | SH |  | SOLE |  | 0 | 0 | 15685 |
| VANGUARD INDEX FDS | VALUE ETF | 922908744 |  | 13222714 | 94199 | SH |  | SOLE |  | 0 | 0 | 94199 |
| VANGUARD SCOTTSDALE FDS | SHRT TRM CORP BD | 92206C409 |  | 363318 | 4832 | SH |  | SOLE |  | 0 | 0 | 4832 |
| VERIZON COMMUNICATIONS INC | COM | 92343V104 |  | 1427265 | 36225 | SH |  | SOLE |  | 0 | 0 | 36225 |
| VERTEX PHARMACEUTICALS INC | COM | 92532F100 |  | 543195 | 1881 | SH |  | SOLE |  | 0 | 0 | 1881 |
| VISA INC | COM CL A | 92826C839 |  | 72820088 | 350501 | SH |  | SOLE |  | 0 | 0 | 350501 |
| VODAFONE GROUP PLC NEW | SPONSORED ADR | 92857W308 |  | 166170 | 16420 | SH |  | SOLE |  | 0 | 0 | 16420 |
| WALMART INC | COM | 931142103 |  | 1077604 | 7600 | SH |  | SOLE |  | 0 | 0 | 7600 |
| WEATHERFORD INTL PLC | ORD SHS | G48833118 |  | 27028540 | 530804 | SH |  | SOLE |  | 0 | 0 | 530804 |
| WELLS FARGO CO NEW | COM | 949746101 |  | 18351919 | 444464 | SH |  | SOLE |  | 0 | 0 | 444464 |
| WORKDAY INC | CL A | 98138H101 |  | 310899 | 1858 | SH |  | SOLE |  | 0 | 0 | 1858 |
| XYLEM INC | COM | 98419M100 |  | 489162 | 4424 | SH |  | SOLE |  | 0 | 0 | 4424 |
| ZEBRA TECHNOLOGIES CORPORATI | CL A | 989207105 |  | 10947169 | 42694 | SH |  | SOLE |  | 0 | 0 | 42694 |
| ZIMMER BIOMET HOLDINGS INC | COM | 98956P102 |  | 4217445 | 33078 | SH |  | SOLE |  | 0 | 0 | 33078 |
| ZOETIS INC | CL A | 98978V103 |  | 59785219 | 407951 | SH |  | SOLE |  | 0 | 0 | 407951 |

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