# EDGAR Filing Document

**Accession Number:** 0001174940
**File Stem:** 0000000000-26-000820
**Filing Date:** 2026-1
**Character Count:** 2195
**Document Hash:** 153d99bc244d2220ff34e8120db6075b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000000000-26-000820.hdr.sgml**: 20260521

**ACCESSION NUMBER**: 0000000000-26-000820

**CONFORMED SUBMISSION TYPE**: UPLOAD

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20260127

**FILED FOR**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ORAGENICS INC
- **CENTRAL INDEX KEY:** 0001174940
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 593410522
- **STATE OF INCORPORATION:** FL
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** UPLOAD
- **SEC FILE NUMBER:** 333-292880

**BUSINESS ADDRESS:**
- **STREET 1:** 9015 TOWN CENTER PARKWAY
- **STREET 2:** SUITE 143
- **CITY:** LAKEWOOD RANCH
- **STATE:** FL
- **ZIP:** 34202
- **BUSINESS PHONE:** 8132867900

**MAIL ADDRESS:**
- **STREET 1:** 9015 TOWN CENTER PARKWAY
- **STREET 2:** SUITE 143
- **CITY:** LAKEWOOD RANCH
- **STATE:** FL
- **ZIP:** 34202
**PUBLIC REFERENCE ACCESSION NUMBER**: 0001493152-26-003241

## Text-Extract

```

                                                           January 27, 2026

Janet Huffman
Chief Executive Officer
Oragenics, Inc.
9015 Town Center Parkway, Suite 143
Lakewood Ranch, FL 34202

       Re: Oragenics, Inc.
           Registration Statement of Form S-3
           Filed January 22, 2026
           File No. 333-292880
Dear Janet Huffman:

       This is to advise you that we have not reviewed and will not review your
registration
statement.

        Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you
that the company and its management are responsible for the accuracy and
adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.

       Please contact Lauren Hamill at 303-844-1008 with any questions.

                                                           Sincerely,

                                                           Division of
Corporation Finance
                                                           Office of Life
Sciences
cc:    Julio Esquivel

```

### Attached PDF Documents

**Attachment 1:** `filename1`

_No text found in this document._