# EDGAR Filing Document

**Accession Number:** 0001457247
**File Stem:** 0001493152-23-003128
**Filing Date:** 2023-1
**Character Count:** 10561
**Document Hash:** 239b8f0ed2b3bad4ecfdabb51caf589d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001493152-23-003128.hdr.sgml**: 20230131

**ACCESSION NUMBER**: 0001493152-23-003128

**CONFORMED SUBMISSION TYPE**: 5

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230131

**DATE AS OF CHANGE**: 20230131

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** CZIRR JAMES C
- **CENTRAL INDEX KEY:** 0001260641

**FILING VALUES:**
- **FORM TYPE:** 5
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-31791
- **FILM NUMBER:** 23572119

**MAIL ADDRESS:**
- **STREET 1:** 4908 SOUTH ASHTON COURT
- **CITY:** SPOKANE
- **STATE:** WA
- **ZIP:** 99223
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** 10X Capital Management, LLC
- **CENTRAL INDEX KEY:** 0001457247
- **STATE OF INCORPORATION:** FL
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 5
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-31791
- **FILM NUMBER:** 23572120

**BUSINESS ADDRESS:**
- **STREET 1:** 1099 FOREST LAKE TERRACE
- **CITY:** NICEVILLE
- **STATE:** FL
- **ZIP:** 32578
- **BUSINESS PHONE:** 850-502-7659

**MAIL ADDRESS:**
- **STREET 1:** 1099 FOREST LAKE TERRACE
- **CITY:** NICEVILLE
- **STATE:** FL
- **ZIP:** 32578
**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** 10X Fund, L.P.
- **CENTRAL INDEX KEY:** 0001453356
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 5
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-31791
- **FILM NUMBER:** 23572121

**BUSINESS ADDRESS:**
- **STREET 1:** 1099 FOREST LAKE TERRACE
- **CITY:** NICEVILLE
- **STATE:** FL
- **ZIP:** 32578
- **BUSINESS PHONE:** 208-263-6695

**MAIL ADDRESS:**
- **STREET 1:** 1099 FOREST LAKE TERRACE
- **CITY:** NICEVILLE
- **STATE:** FL
- **ZIP:** 32578

**FORMER NAME:**
- **FORMER CONFORMED NAME:** 10X FUND LP
- **DATE OF NAME CHANGE:** 20090107
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** GALECTIN THERAPEUTICS INC
- **CENTRAL INDEX KEY:** 0001133416
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 043562325
- **STATE OF INCORPORATION:** NV
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 4960 PEACHTREE INDUSTRIAL BOULEVARD
- **STREET 2:** SUITE 240
- **CITY:** NORCROSS
- **STATE:** GA
- **ZIP:** 30071
- **BUSINESS PHONE:** 678-620-3186

**MAIL ADDRESS:**
- **STREET 1:** 4960 PEACHTREE INDUSTRIAL BOULEVARD
- **STREET 2:** SUITE 240
- **CITY:** NORCROSS
- **STATE:** GA
- **ZIP:** 30071

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PRO PHARMACEUTICALS INC
- **DATE OF NAME CHANGE:** 20010612

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 5

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[ ] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>10X Fund, L.P.<br><sub>(Last) (First) (Middle)</sub><br>545 DUTCH VALLEY ROAD, N.E., SUITE A<br><sub>(Street)</sub><br>ATLANTA,, GA 30324<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2022-12-31 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>GALECTIN THERAPEUTICS INC [ GALT ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>10X Capital Management, LLC<br><sub>(Last) (First) (Middle)</sub><br>545 DUTCH VALLEY ROAD, N.E., SUITE A<br><sub>(Street)</sub><br>ATLANTA,, GA 30324<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2022-12-31 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>GALECTIN THERAPEUTICS INC [ GALT ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>CZIRR JAMES C<br><sub>(Last) (First) (Middle)</sub><br>545 DUTCH VALLEY ROAD, N.E., SUITE A<br><sub>(Street)</sub><br>ATLANTA,, GA 30324<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2022-12-31 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[X] Director [X] 10% Owner<br>[ ] Officer (give title below) [ ] Other (specify below)<br>_ _ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>GALECTIN THERAPEUTICS INC [ GALT ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[ ] Form filed by One Reporting Person<br>[X] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Common Stock | 2022-07-29 |  | J<sup>(1)</sup> |  | 33496 | D | <sup>(1)</sup> | 6135444 | D<sup>(2)</sup> |  |
| Common Stock | 2022-07-29 |  | J<sup>(1)</sup> |  | 90586 | D | <sup>(1)</sup> | 6044858 | D<sup>(2)</sup> |  |
| Common Stock | 2022-12-21 |  | J<sup>(1)</sup> |  | 17117 | D | <sup>(1)</sup> | 6027741 | D<sup>(2)</sup> |  |
| Common Stock | 2022-12-21 |  | J<sup>(1)</sup> |  | 16050 | D | <sup>(1)</sup> | 6011691 | D<sup>(2)</sup> |  |
| Common Stock | 2022-12-21 |  | J<sup>(1)</sup> |  | 3077 | D | <sup>(1)</sup> | 6008614 | D<sup>(2)</sup> |  |
| Common Stock | 2022-12-21 |  | J<sup>(1)</sup> |  | 61407 | D | <sup>(1)</sup> | 5947207 | D<sup>(2)</sup> |  |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

---

### Footnotes:

(1) Shares were distributed in an in-kind distribution to a withdrawing limited partner of 10X Fund, LP of his/her/its pro rata share of shares held by 10X Fund, LP, which did not receive any consideration for the transfer. The distribution is exempt from Section 16(b) because it does not constitute a sale of a security under applicable law.

(2) 10X Fund, L.P. has direct beneficial ownership of all the securities owned by 10X Fund, L.P. 10X Capital Management, LLC, a Florida limited liability company, is the general partner of 10X Fund, L.P., a Delaware limited partnership, and may be deemed to have indirect beneficial ownership of all or a portion of the securities owned directly by 10X Fund, L.P., but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein. James C. Czirr is the manager of 10X Capital Management, LLC, and may be deemed to have indirect beneficial ownership of all or a portion of the securities owned directly by 10X Fund, L.P. and 10X Capital Management, LLC., but disclaims beneficial ownership of the reported securities except to the extent of his pecuniary interest therein.

**Signature:** /s/ James C. Czirr, as Managing Member of the General Partner for 10X Fund, LP  
**Date:** 2023-01-31

**Signature:** /s/ James C. Czirr, as Managing Member of 10X Capital Management, LLC  
**Date:** 2023-01-31

**Signature:** /s/ James C. Czirr, Individually  
**Date:** 2023-01-31

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**