# EDGAR Filing Document

**Accession Number:** 0001075880
**File Stem:** 0001193125-26-116176
**Filing Date:** 2026-3
**Character Count:** 50168
**Document Hash:** 34f205d642d38934a2e1872d68db9a77
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-116176.hdr.sgml**: 20260319

**ACCESSION NUMBER**: 0001193125-26-116176

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 72

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260319

**DATE AS OF CHANGE**: 20260319

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** KAZIA THERAPEUTICS LTD
- **CENTRAL INDEX KEY:** 0001075880
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** C3
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-29962
- **FILM NUMBER:** 26775157

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** THREE INTERNATIONAL TOWERS LEVEL 24,
- **STREET 2:** 300 BARANGAROO AVENUE
- **CITY:** SYDNEY NSW
- **PROVINCE COUNTRY:** C3
- **ZIP:** 2000
- **BUSINESS PHONE:** 01161298780088

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** THREE INTERNATIONAL TOWERS LEVEL 24,
- **STREET 2:** 300 BARANGAROO AVENUE
- **CITY:** SYDNEY NSW
- **PROVINCE COUNTRY:** C3
- **ZIP:** 2000

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** NOVOGEN LTD
- **DATE OF NAME CHANGE:** 19981228

?xml version='1.0' encoding='ASCII'? 6-K

### UNITED STATES

### SECURITIES AND EXCHANGE COMMISSION

#### Washington, D.C. 20549

### Form 6-K

#### REPORT OF FOREIGN PRIVATE ISSUER

#### PURSUANT TO RULE 13a-16 OR 15d-16

#### UNDER THE SECURITIES EXCHANGE ACT OF 1934

#### For the month of March , 2026

#### Commission File Number 000-29962

## Kazia Therapeutics Limited

#### (Translation of registrant's name into English)

#### Three International Towers Level 24 300 Barangaroo Avenue Sydney NSW 2000

#### (Address of principal executive office)
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒ Form 40-F ☐

------

#### INFORMATION CONTAINED IN THIS FORM 6-K REPORT
On March 16, 2026 AEDT, Kazia Therapeutics Limited (the "Company") reported its unaudited half-year results for the six months ended December 31, 2025, a copy of which is attached to this Form 6-K as Exhibit 99.1.

The Company hereby incorporates by reference the information contained herein, including Exhibit 99.1, into the Company's registration statements on Form F-3 (File No. 333-281937).

------

#### EXHIBIT LIST

---

| | |
|:---|:---|
| Exhibit | Description |
| 99.1 | Half-year report for the six months ended December 31, 2025 |
| 101.INS | XBRL Instance Document |
| 101.SCH | XBRL Taxonomy Extension Schema Document |
| 101.CAL | XBRL Taxonomy Extension Calculation Linkbase Document |
| 101.DEF | XBRL Taxonomy Extension Definition Linkbase Document |
| 101.LAB | XBRL Taxonomy Extension Label Linkbase Document |
| 101.PRE | XBRL Taxonomy Extension Presentation Linkbase Document |
| 104 | Cover Page Interactive Data File (embedded within the Inline XBRL document) |

---

------

#### SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

---

| |
|:---|
| **Kazia Therapeutics Limited** (Registrant) |
| /s/ John Friend |
| Name: John Friend |
| Title: Chief Executive Officer |
| Date: March 19, 2026 |

---

------

## Exhibit 99.1

?xml version='1.0' encoding='ASCII'? EX-99.1

#### Exhibit 99.1
![](g45630g52z59.jpg)

#### Kazia Therapeutics Limited

#### ABN 37 063 259 754

#### Half Yearly Report - 31 December 2025

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---

| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Directors' report<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

The directors present their report, together with the financial statements, on the Consolidated entity (referred to hereafter as the 'Consolidated entity') consisting of Kazia Therapeutics Limited (referred to hereafter as the 'Consolidated entity' or 'parent entity') and the entities it controlled at the end of, or during, the half-year ended 31 December 2025.

#### Directors
The following persons were directors of Kazia Therapeutics Limited during the whole of the financial year and up to the date of this report, unless otherwise stated:

Dr John Friend

Bryce Carmine

Steven Coffey

Ebru Davidson

Robert Apple

#### Principal activities
During the financial year the principal continuing activity of the Consolidated entity consisted of pharmaceutical research and development with a view to commercialising the results of our research through license transactions or other means.

#### Review of operations
The loss for the Consolidated entity after providing for income tax amounted to $12,552,490 (31 December 2024: $10,453,811).

The attached financial statements detail the performance and financial position of the Consolidated entity for the half-year ended 31 December 2025.

Cash resources

At 31 December 2025, the Consolidated entity had total funds of $69,459,980 comprising cash in hand and at bank.

Going concern

For the period ended 31 December 2025 the Consolidated Entity incurred a loss after income tax of $12,552,490 (31 December 2024: $10,453,811), was in a net current asset position of $45,612,689 (30 June 2025 net current liability: $9,119,727) and had net cash outflows from operating activities of $9,540,623 (31 December 2024: $8,420,244) for the half-year ended 31 December 2025.

The Directors note the following with regards to the ability of the Consolidated Entity to continue as a going concern:

• During the period, the Company received notifications from Nasdaq regarding non-compliance with the minimum Market Value of Listed Securities requirement. On 18 December 2025, the Nasdaq Office of General Counsel confirmed that the Company had regained compliance with Listing Rule 5550(b) and remained in compliance with all applicable listing standards. Accordingly, the Company's ADSs continue to trade on The Nasdaq Capital Market.

• The Consolidated Entity continued to access capital markets during the period. Capital raised in the period, including the PIPE entered on 2nd December 2025 which raised US$46.51 million after deducting offering expenses has resulted in a cash balance of AUD 69.46 million at 31 December 2025. The Directors have considered the Consolidated Entity's cash flow forecasts for a period of at least 12 months from the date of this report, together with available cash and capital-raising mechanisms, and believe that the Group will be able to meet its obligations as and when they fall due.

Accordingly, the financial statements have been prepared on a going concern basis which assumes continuity of normal activities and the realisation of assets and the settlement of liabilities in the ordinary course of business.

------

---

| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Directors' report<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

Research and development report

During the reporting period (July 1, 2025 to December 31, 2025), the Consolidated entity advanced paxalisib beyond neuro-oncology into multiple breast cancer translational and clinical settings, including a Company-sponsored Phase 1b study in metastatic triple-negative breast cancer (TNBC), collaborative ex vivo studies in HER2-positive metastatic breast cancer, and expanded-access real-world use. On 10 July 2025, the Company reported preliminary results from the first patient in its Phase 1b paxalisib combination regimen (paxalisib + pembrolizumab + standard chemotherapy) after 21 days of dosing, including a >50% reduction in circulating tumor cells (CTCs) and a notable decrease in CTC clusters.

On 1 August 2025, the Company announced an approximately $2.0 million private placement at a premium to market, with proceeds intended to support continued clinical development of the company's lead programs, including paxalisib and EVT801.

On 11 September 2025, the Company announced new findings from a collaborative research program led by Professor Sudha Rao at QIMR Berghofer, reporting that paxalisib monotherapy demonstrated a statistically significant reduction in single CTCs and complete (100%) disruption of CTC clusters (<u>></u>3 cells) in ex vivo blood samples from stage IV HER2-positive metastatic breast cancer patients.

On 2 October 2025, the Company reported an expanded-access case in metastatic TNBC treated with a combination immunotherapy/chemotherapy regimen plus paxalisib, in which imaging after three weeks of treatment demonstrated an 86% reduction in overall tumor burden.

In October 2025, the Company also expanded its immuno-oncology pipeline through an exclusive collaboration and in-licensing agreement with QIMR Berghofer for a first-in-class PD-L1 protein degrader program (lead optimized compound NDL2), intended to address resistance mechanisms not reached by existing checkpoint inhibitors.

On 27 October 2025, the Company announced its intention to request a follow-up FDA Type C meeting to discuss overall survival findings in newly diagnosed glioblastoma patients treated with paxalisib and to seek feedback on a potential regulatory pathway aligned with the FDA Oncology Center of Excellence's Project FrontRunner initiative.

On 18 November 2025, the Company provided a clinical update describing an initial immune-complete response (iCR) in metastatic TNBC in an expanded-access setting and a broader Q4 business update across breast cancer immuno-oncology and GBM regulatory strategy.

In December 2025, the Company reported additional momentum across both R&D execution and corporate runway. On 2 December 2025, the Company announced the pricing of an approximately $50.0 million private placement of equity securities, with expected net proceeds of approximately $46.5 million after fees and expenses, intended to support continued clinical development programs. On 10 December 2025, the Company announced new data from two presentations at the 2025 San Antonio Breast Cancer Symposium (SABCS), describing mechanistic and early clinical evidence supporting paxalisib activity across HER2-positive metastatic breast cancer and TNBC.

#### Significant changes in the state of affairs
As noted in the 'Going concern' section of this Directors report, the Company entered into two securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE).

Apart from this change, there were no other significant changes in the state of affairs of the Consolidated entity during the financial half-year.

#### Matters subsequent to the end of the financial half-year
No matter or circumstance has arisen since 31 December 2025 that has significantly affected, or may significantly affect the Consolidated entity's operations, the results of those operations, or the Consolidated entity's state of affairs in future financial years.

#### Auditors independence declaration
A copy of the auditors independence declaration as required under section 307C of the Corporations Act 2001 is set out immediately after this directors report.

------

---

| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Directors' report<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

This report is made in accordance with a resolution of Directors, pursuant to section 298(2)(a) of the Corporations Act 2001.

On behalf of the Directors

---

| |
|:---|
| /s/ Steven Coffey |
| Steven Coffey<br>Director |
| 16 March 2026 |
| Sydney |

---

------

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| | | |
|:---|:---|:---|
| ![](g45630g79v93.jpg) | Tel: +61 2 9251 4100<br>Fax: +61 2 9240 9821<br>www.bdo.com.au | Parkline Place<br>Level 25, 252 Pitt Street<br>Sydney NSW 2000 Australia |

---

#### DECLARATION OF INDEPENDENCE BY GARETH FEW TO THE DIRECTORS OF KAZIA THERAPEUTICS LIMITED
As lead auditor for the review of Kazia Therapeutics Limited for the half-year ended 31 December 2025, I declare that, to the best of my knowledge and belief, there have been:

1. No contraventions of the auditor independence requirements of the Corporations Act 2001 in relation to the review; and

2. No contraventions of any applicable code of professional conduct in relation to the review.

This declaration is in respect of Kazia Therapeutics Limited and the entities it controlled during the period.

---

| |
|:---|
| /s/ Gareth Few |
| Gareth Few<br>Director |
| BDO Audit Pty Ltd |
| Sydney, 16 March 2026 |

---

BDO Audit Pty Ltd ABN 33 134 022 870 is a member of a national association of independent entities which are all members of BDO International Ltd, a UK company limited by guarantee, and form part of the international BDO network of independent member firms. Liability limited by a scheme approved under Professional Standards Legislation.

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Contents<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

---

| | |
|:---|:---|
| [Statement of profit or loss and other comprehensive income](#ex99_145630_1) | 6 |
| [Statement of financial position](#ex99_145630_2) | 7 |
| [Statement of changes in equity](#ex99_145630_3) | 8 |
| [Statement of cash flows](#ex99_145630_4) | 9 |
| [Notes to the financial statements](#ex99_145630_5) | 10 |
| [Directors' declaration](#ex99_145630_6) | 19 |
| [Independent auditor's review report to the members of Kazia Therapeutics Limited](#ex99_145630_7) | 20 |

---

#### General information
The financial statements cover Kazia Therapeutics Limited as a Consolidated entity consisting of Kazia Therapeutics Limited and the entities it controlled at the end of, or during, the half-year. The financial statements are presented in Australian dollars, which is Kazia Therapeutics Limited's functional and presentation currency.

Kazia Therapeutics Limited is a public Consolidated entity limited by shares, incorporated and domiciled in Australia. Its registered office and principal place of business is:

Three International Towers

Level 24, 300 Barangaroo Avenue

Sydney NSW 2000

A description of the nature of the Consolidated entity's operations and its principal activities are included in the directors report, which is not part of the financial statements.

The financial statements were authorised for issue, in accordance with a resolution of directors, on 16 March 2026.

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>**Statement of profit or loss and other comprehensive income**<br>For the half-year ended 31 December 2025 | ![](g45630g52z59.jpg) |

---

---

| | | | |
|:---|:---|:---|:---|
|  | | Consolidated | Consolidated |
|  | Note | December<br> 2025<br>$ | December<br> 2024<br>$ |
| Revenue and other income |  |  |  |
| Other income |  | 91921 | 22290 |
| Finance Income |  | 160923 | 28667 |
| Expenses |  |  |  |
| Research and development expense |  | (4992238) | (4282101) |
| General and administrative expense | 3 | (8558016) | (5108573) |
| Fair value gain/(loss) on financial liabilities |  | 744920 | (1999648) |
| Gain on revaluation of contingent consideration |  |  | 750008 |
| Loss before income tax benefit |  | (12552490) | (10589357) |
| Income tax benefit |  |  | 135546 |
| Loss after income tax benefit for the half-year attributable to the owners of Kazia Therapeutics Limited |  | (12552490) | (10453811) |
| Other comprehensive (loss) / income |  |  |  |
| Items that may be reclassified subsequently to profit or loss |  |  |  |
| Net exchange difference on translation of financial statements of foreign controlled entities, net of tax |  | (859893) | 174335 |
| Other comprehensive (loss) / income for the half-year, net of tax |  | (859893) | 174335 |
| Total comprehensive loss for the half-year attributable to the owners of Kazia Therapeutics Limited |  | (13412383) | (10279476) |
|  |  | Cents | Cents |
| Basic loss per share | 17 | (0.805) | (2.459) |
| Diluted loss per share | 17 | (0.805) | (2.459) |

---

The above statement of profit or loss and other comprehensive income should be read in conjunction with the accompanying notes

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>**Statement of financial position**<br>As at 31 December 2025 | ![](g45630g52z59.jpg) |

---

---

| | | | |
|:---|:---|:---|:---|
|  | | Consolidated | Consolidated |
|  | Note | December<br>2025<br>$ | June 2025<br>$ |
| Assets |  |  |  |
| Current assets |  |  |  |
| Cash and cash equivalents | 4 | 69459980 | 4344691 |
| Trade and other receivables | 5 | 315539 | 97911 |
| Other assets | 6 | 210498 | 490558 |
| Total current assets |  | 69986017 | 4933160 |
| Non-current assets |  |  |  |
| Trade and other receivables | 5 | 40000 | 40000 |
| Intangibles | 7 | 1086516 | 1086516 |
| Total non-current assets |  | 1126516 | 1126516 |
| Total assets |  | 71112533 | 6059676 |
| Liabilities |  |  |  |
| Current liabilities |  |  |  |
| Trade and other payables | 8 | 9648456 | 10116769 |
| Other financial liabilities | 9 | 14180627 | 3150301 |
| Borrowings | 10 | 98807 | 395640 |
| Employee benefits provision | 11 | 445438 | 390177 |
| Total current liabilities |  | 24373328 | 14052887 |
| Non-current liabilities |  |  |  |
| Deferred tax liability | 12 | 271629 | 271629 |
| Employee benefits provision | 11 | 537 | 36609 |
| Total non-current liabilities |  | 272166 | 308238 |
| Total liabilities |  | 24645494 | 14361125 |
| Net assets/(liabilities) |  | 46467039 | (8301449) |
| Equity |  |  |  |
| Contributed equity | 13 | 186592055 | 123045889 |
| Other contributed equity | 14 | 380224 | 380224 |
| Reserves | 15 | 5104456 | 3099687 |
| Accumulated losses |  | (145609696) | (134827249) |
| Total equity/(deficiency) |  | 46467039 | (8301449) |

---

The above statement of financial position should be read in conjunction with the accompanying notes

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>**Statement of changes in equity**<br>For the half-year ended 31 December 2025 | ![](g45630g52z59.jpg) |

---

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| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| Consolidated | Contributed<br> equity<br>$ | Other<br> contributed<br> equity<br>$ | Share based<br> payment<br> reserve<br>$ | Foreign<br> currency<br> translation<br> reserve<br>$ | Accumulated<br> losses<br>$ | Total deficit<br>$ |
| Balance at 1 July 2024 | 101637758 |  | 4224946 | (750191) | (115130270) | (10017757) |
| Loss after income tax benefit for the half-year |  |  |  |  | (10453811) | (10453811) |
| Other comprehensive income for the half-year, net of tax |  |  |  | 174335 |  | 174335 |
| Total comprehensive income for the half-year |  |  |  | 174335 | (10453811) | (10279476) |
| Issue of shares | 16387602 |  |  |  |  | 16387602 |
| Transactions with owners in their capacity as owners: |  |  |  |  |  |  |
| Share issue costs | (187965) |  |  |  |  | (187965) |
| Unissued equity | (380224) | 380224 |  |  |  |  |
| Employee share-based payment options - expired |  |  | (495900) |  | 495900 |  |
| Employee share-based payment options |  |  | 290053 |  |  | 290053 |
| Balance at 31 December 2024 | 117457171 | 380224 | 4019099 | (575856) | (125088181) | (3807543) |

---

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| Consolidated | Contributed<br> equity<br>$ | Other<br> contributed<br> equity<br>$ | Share based<br> payment<br> reserve<br>$ | Foreign<br> currency<br> translation<br> reserve<br>$ | Accumulated<br> losses<br>$ | Total equity<br>$ |
| Balance at 1 July 2025 | 123045889 | 380224 | 3873198 | (773511) | (134827249) | (8301449) |
| Loss after income tax expense for the half-year |  |  |  |  | (12552490) | (12552490) |
| Other comprehensive loss for the half-year, net of tax |  |  |  | (859893) |  | (859893) |
| Total comprehensive loss for the half-year |  |  |  | (859893) | (12552490) | (13412383) |
| Transactions with owners in their capacity as owners: |  |  |  |  |  |  |
| Issue of shares | 65248181 |  |  |  |  | 65248181 |
| Share issue costs | (1702015) |  |  |  |  | (1702015) |
| Employee share-based payment options - expired |  |  | (1770043) |  | 1770043 |  |
| Employee share-based payment options |  |  | 4634705 |  |  | 4634705 |
| Balance at 31 December 2025 | 186592055 | 380224 | 6737860 | (1633404) | (145609696) | 46467039 |

---

The above statement of changes in equity should be read in conjunction with the accompanying notes

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>**Statement of cash flows**<br>For the half-year ended 31 December 2025 | ![](g45630g52z59.jpg) |

---

---

| | | | |
|:---|:---|:---|:---|
|  | | Consolidated | Consolidated |
|  | Note | December<br> 2025<br>$ | December<br> 2024<br>$ |
| Cash flows from operating activities |  |  |  |
| Other Income |  | 91921 |  |
| Payments to suppliers (inclusive of GST) |  | (9793467) | (8420244) |
|  |  | (9701546) | (8420244) |
| Interest received |  | 160923 |  |
| Net cash used in operating activities | 18 | (9540623) | (8420244) |
| Cash flows from financing activities |  |  |  |
| Proceeds from issue of shares (net of costs) | 13 | 53735958 | 8561589 |
| Proceeds from issue of pre-funded warrants | 9 | 21585452 | 1178106 |
| Net cash from financing activities |  | 75321410 | 9739695 |
| Net increase in cash and cash equivalents |  | 65780787 | 1319451 |
| Cash and cash equivalents at the beginning of the financial half-year |  | 4344691 | 1657478 |
| Effects of exchange rate changes on cash and cash equivalents |  | (665498) | 87379 |
| Cash and cash equivalents at the end of the financial half-year | 4 | 69459980 | 3064308 |

---

The above statement of cash flows should be read in conjunction with the accompanying notes

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>**Notes to the financial statements**<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 1. Material accounting policy information
These general purpose financial statements for the interim half-year reporting period ended 31 December 2025 have been prepared in accordance with Australian Accounting Standard AASB 134 Interim Financial Reporting and the Corporations Act 2001, as appropriate for for-profit oriented entities. Compliance with AASB 134 ensures compliance with International Financial Reporting Standard IAS 34 Interim Financial Reporting.

These general purpose financial statements do not include all the notes of the type normally included in annual financial statements. Accordingly, these financial statements are to be read in conjunction with the annual report for the year ended 30 June 2025 and any public announcements made by the Consolidated entity during the interim reporting period in accordance with the continuous disclosure requirements of the Corporations Act 2001.

The accounting policies adopted are consistent with those of the previous financial year and corresponding interim reporting period, unless otherwise stated.

#### Classification and initial measurement of financial assets
The Consolidated entity's other financial liabilities comprise derivatives in respect of prefunded and ordinary warrants. Prefunded and ordinary warrants are measured at fair value through profit or loss. All transactions costs in relation to the warrants are expensed immediately. Changes to the fair value of the instruments post issue will be recognised in profit or loss.

#### New or amended Accounting Standards and Interpretations adopted
The Consolidated entity has adopted all of the new, revised or amending Accounting Standards and Interpretations issued by the Australian Accounting Standards Board (AASB) that are mandatory for the current reporting period. Any new, revised or amending Accounting Standards or Interpretations that are not yet mandatory have not been early adopted. The adoption of these Accounting Standards and Interpretations did not have any significant impact on the financial performance or position of the Consolidated entity.

#### Going concern
For the period ended 31 December 2025 the Consolidated Entity incurred a loss after income tax of $12,552,490 (31 December 2024: $10,453,811), was in a net current asset position of $45,612,689 (30 June 2025 net current liability: $9,119,727) and had net cash outflows from operating activities of $9,540,623 (31 December 2024: $8,420,244) for the half-year ended 31 December 2025.

The Directors note the following with regards to the ability of the Consolidated Entity to continue as a going concern:

• During the period, the Company received notifications from Nasdaq regarding non-compliance with the minimum Market Value of Listed Securities requirement. On 18 December 2025, the Nasdaq Office of General Counsel confirmed that the Company had regained compliance with Listing Rule 5550(b) and remained in compliance with all applicable listing standards. Accordingly, the Company's ADSs continue to trade on The Nasdaq Capital Market.

• The Consolidated Entity continued to access capital markets during the period. Capital raised in the period, including the PIPE entered on 2nd December 2025 which raised US$46.51 million after deducting offering expenses has resulted in a cash balance of AUD 69.46 million at 31 December 2025. The Directors have considered the Consolidated Entity's cash flow forecasts for a period of at least 12 months from the date of this report, together with available cash and capital-raising mechanisms, and believe that the Group will be able to meet its obligations as and when they fall due.

Accordingly, the financial statements have been prepared on a going concern basis which assumes continuity of normal activities and the realisation of assets and the settlement of liabilities in the ordinary course of business.

------

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 2. Critical accounting judgements, estimates and assumptions
When preparing the half-year financial statements, management undertakes a number of judgements, estimates and assumptions about recognition and measurement of assets, liabilities, income and expenses. The actual results may differ from the judgements, estimates and assumptions made by management and will seldom equal the estimated results.

The judgments, estimates and assumptions applied in the half-year financial statements, including key sources of estimation uncertainty were the same as those applied in the Consolidated entity's last annual financial statements for the year ended 30 June 2025.

#### Note 3. Expenses

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | December<br>2024<br>$ |
| Loss before income tax includes the following specific expenses: |  |  |
| Amortisation |  |  |
| Amortisation |  | 934710 |
| Interest expense |  |  |
| Borrowings | 7263 | 10033 |
| Contingent consideration - Effective interest |  | 223035 |
|  | 7263 | 233068 |
| Superannuation expense |  |  |
| Defined contribution superannuation expense | 27900 | 26738 |
| Employee benefits expense excluding superannuation |  |  |
| Employee benefits expense excluding superannuation | 1381820 | 1138052 |
| Share based payment expense |  |  |
| Share based payment expense | 4634705 | 290053 |

---

#### Note 4. Cash and cash equivalents

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br>2025<br>$ |
| Current assets |  |  |
| Cash at bank and on hand | 69459980 | 4344691 |

---

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

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#### Note 5. Trade and other receivables

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br>2025<br>$ |
| Current assets |  |  |
| Deposits held | 7687 | 7687 |
| BAS receivable | 307852 | 90224 |
|  | 315539 | 97911 |
| Non-current assets |  |  |
| Corporate credit card deposit | 40000 | 40000 |
|  | 355539 | 137911 |

---

#### Note 6. Other assets

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br>2025<br>$ |
| Current assets |  |  |
| Prepayments | 210498 | 490558 |

---

Other assets contain the prepayment of invoices in relation to the annual insurance renewal program and an offsetting borrowing for the funding of this prepayment in included in Borrowings - See Note 10 'Borrowings'.

#### Note 7. Intangibles

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br>2025<br>$ |
| Non-current assets |  |  |
| Licensing agreement - Paxalisib | 1086516 | 1086516 |

---

Reconciliations

Reconciliations of the written down values at the beginning and end of the current financial half-year are set out below:

---

| | | |
|:---|:---|:---|
| Balance at 1 July 2025 | 1086516.0 | 1086516.0 |
| Balance at 31 December 2025 | 1086516.0 | 1086516.0 |

---

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

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#### Note 8. Trade and other payables

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br>2025<br>$ |
| Current liabilities |  |  |
| Trade payables | 6127338 | 5644797 |
| Accrued and other payables | 3521118 | 4471972 |
|  | 9648456 | 10116769 |

---

#### Note 9. Other financial liabilities

---

| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br>2025<br>$ |
| Current liabilities |  |  |
| Prefunded and ordinary warrants | 14180627 | 3150301 |

---

Reconciliation

Reconciliation of the written down values at the beginning and end of the current and previous financial year end are set out below:

---

| | | |
|:---|:---|:---|
| Opening balance | 3150301 | 6478060 |
| Prefunded and ordinary warrants at initial recognition | 21585452 | 3034625 |
| Prefunded warrants exercised | (9810204) | (8840101) |
| Gain / Loss on remeasurement of other financial liabilities | (744920) | 2477717 |
| Closing balance | 14180627 | 3150301 |

---

On 25 July 2025 Maxim Partners LLC exercised a net settlement of warrants and was issued 1,057,000 ordinary shares.

On 31 July 2025 the Consolidated Entity entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$2,049,992, after deducting offering expenses. Pursuant to the Purchase Agreement, the Consolidated Entity agreed to offer and sell in the Private Placement to such Purchasers (i) 14,204,500 ordinary shares at a purchase price of $0.0176 per Share, and (ii) pre-funded warrants to purchase up to 204,547 American Depositary Shares ("ADSs"), each ADS representing five hundred Ordinary Shares, at a purchase price of $8.7999 per Pre-Funded Warrant. Each Pre-Funded Warrant is exercisable for one ADS at an exercise price of $0.0001 and are exercisable immediately and will expire when exercised in full. The pre-funded Warrants were determined to be classified as a financial liability and a derivative under AASB 132 "Financial Instruments: Presentation" accounted for at fair value through profit and loss because they are denominated in a foreign currency, causing the value to vary with the USD/AUD exchange rate and the Consolidated Entity's share price, requires a smaller net investment, and is settled at a future date. The initial fair value of the pre-funded Warrants was A$2,600,115.

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 9. Other financial liabilities (continued)
On 2 December 2025 the Consolidated Entity entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$46,509,833, after deducting offering expenses. Pursuant to the Purchase Agreement, the Consolidated Entity agreed to offer and sell in the Private Placement to such Purchasers (i) 4,530,854,000 ordinary shares at a purchase price of $0.01 per Share, and (ii) pre-funded warrants to purchase up to 938,490 American Depositary Shares ("ADSs"), each ADS representing five hundred Ordinary Shares, at a purchase price of $4.9999 per Pre-Funded Warrant. Each Pre-Funded Warrant is exercisable for one ADS at an exercise price of $0.0001 and are exercisable immediately and will expire when exercised in full. The pre-funded Warrants were determined to be classified as a financial liability and a derivative under AASB 132 "Financial Instruments: Presentation" accounted for at fair value through profit and loss because they are denominated in a foreign currency, causing the value to vary with the USD/AUD exchange rate and the Consolidated Entity's share price, requires a smaller net investment, and is settled at a future date. The initial fair value of the pre-funded Warrants was A$18,985,338. Transaction costs of A$5,278,293 were incurred and allocated on a pro rata basis between the equity and derivative liability components with the portion allocated to the derivative liability component expensed immediately.

On 10 December 2025 Alumni Capital LP exercised a net settlement of warrants and was issued 219,841,000 ordinary shares.

#### Note 10. Borrowings

---

| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br> 2025<br>$ |
| Current liabilities |  |  |
| Insurance premium funding | 98807 | 395640 |

---

Borrowings relate to the annual insurance renewal program. An offsetting prepayment of insurance invoices is included in Prepayments - See Note 6 'Other assets'.

#### Note 11. Employee benefits

---

| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br> 2025<br>$ |
| Current liabilities |  |  |
| Annual leave | 405833 | 390177 |
| Long service leave | 39605 |  |
|  | 445438 | 390177 |
| Non-current liabilities |  |  |
| Long service leave | 537 | 36609 |
|  | 445975 | 426786 |

---

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 12. Deferred tax liability

---

| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | June<br> 2025<br>$ |
| Non-current liabilities |  |  |
| Deferred tax liability associated with Licencing Agreement | 271629 | 271629 |

---

The Company has completed an analysis of the availability of historical tax losses to offset the deferred tax liability, concluding that the historical tax losses are not expected to be available for offset against the deferred tax liability.

#### Note 13. Contributed equity

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| | | | | |
|:---|:---|:---|:---|:---|
| | Consolidated | Consolidated | Consolidated | Consolidated |
| | December 2025<br>Shares | June 2025<br>Shares | December<br>2025<br>$ | June 2025<br>$ |
| | December 2025<br>Shares | June 2025<br>Shares | December<br>2025<br>$ | June 2025<br>$ |
| | December 2025<br>Shares | June 2025<br>Shares | December<br>2025<br>$ | June 2025<br>$ |
| Ordinary shares - fully paid | 5667995734 | 809418734 | 186592055 | 123045889 |

---

Movements in share capital

---

| | | | | |
|:---|:---|:---|:---|:---|
| Details | Date | Shares | Issue<br> price | $ |
| Balance | 1 July 2025 | 809418734 |  |  |
| Maxim Warrants Net Settlement | 25 July 2025 | 1057000 | $0.0882 |  |
| August PIPE | 5 August 2025 | 14204500 | $0.0412 |  |
| ATM issue of shares No. 65 | 20 August 2025 | 650000 | $0.0229 |  |
| ATM issue of shares No. 66 | 27 August 2025 | 1382500 | $0.0255 |  |
| ATM issue of shares No. 67 | 12 September 2025 | 8576000 | $0.0255 |  |
| ATM issue of shares No. 68 | 3 October 2025 | 82012000 | $0.0234 |  |
| December PIPE – (Net of transaction costs) | 3 December 2025 | 4530854000 | $0.0116 |  |
| Alumni Warrants Net Settlement | 10 December 2025 | 219841000 | $0.0442 |  |
| Less: share issue transaction costs |  |  | $0.0000) |  |
| Balance | 31 December 2025 | 5667995734 |  |  |

---

The at-the-market equity program ("ATM") allows the Company to raise capital dynamically in the market, which no discount, no warrant coverage, and modest banking fees, allowing it to fund operations with minimal dilution to existing shareholders. An ATM with Oppenheimer & Co. Inc. (Oppenheimer) as sales agent was established in April 2022. Under the ATM, Kazia may offer and sell via Oppenheimer, in the form of American Depository Shares (ADSs), with each ADS representing 500 ordinary shares. Kazia entered into an Equity Distribution Agreement, dated as of 22 April 2022 (the "Sales Agreement"), with Oppenheimer, acting as sales agent for an initial capacity of US$35 million. On 4 September 2024, the Equity Distribution Agreement was amended to increase the aggregate offering price to US$50 million. On 10 July 2025, the Company terminated the ATM with Oppenheimer and on July 25, 2025, Kazia entered into an At the Market Offering Agreement with Rodman & Renshaw LLC ("Rodman"), as sales agent under which the Company may offer and sell, from time to time through Rodman, American Depositary Shares ("ADSs"), each ADS representing five hundred (500) ordinary shares, no par value per share, of the Company (the "Ordinary Shares").

From July through December 2025, the Consolidated entity raised total proceeds, net of expenses of US$1,397,016 using the ATM facility, the remaining capacity of the ATM was US$35.19 million.

On 25 July 2025 Maxim Partners LLC exercised a net settlement of warrants and was issued 1,057,000 ordinary shares.

On 31 July 2025 the Company entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$1.80 million, after deducting offering expenses.

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 13. Contributed equity (continued)
On 2 December 2025 the Company entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$46.51 million, after deducting offering expenses.

On 10 December 2025 Alumni Capital LP exercised a net settlement of warrants and was issued 219,841,000 ordinary shares.

Ordinary shares

Ordinary shares entitle the holder to participate in dividends and the proceeds on the winding up of the Consolidated entity in proportion to the number of and amounts paid on the shares held. The fully paid ordinary shares have no par value and the Consolidated entity does not have a limited amount of authorised capital.

On a show of hands every member present at a meeting in person or by proxy shall have one vote and upon a poll each share shall have one vote.

Share buy-back

There is no current on-market share buy-back.

Capital risk management

The Consolidated entity's objectives when managing capital are to safeguard its ability to continue as a going concern, so that it can provide returns for shareholders and benefits for other stakeholders and to maintain an optimum capital structure to reduce the cost of capital.

Capital is regarded as total equity, as recognised in the statement of financial position, plus net debt. Net debt is calculated as total borrowings less cash and cash equivalents.

The capital structure of the Consolidated entity consists of cash and cash equivalents and equity attributable to equity holders. The overall strategy of the Consolidated entity is to continue its drug development programs, which depends on raising sufficient funds, through a variety of sources including issuing of additional share capital, as may be required from time to time.

The capital risk management policy remains unchanged from the prior year.

#### Note 14. Unissued equity
On 23 October 2023, the Company entered into a securities purchase agreement with an accredited investor, pursuant to which the Company issued a six-month unsecured convertible promissory note (the "Note") in the principal amount of A$776,670 (US$500,000). The Note bears interest at a rate of 10% per annum. On 23 December 2023 the investor called upon 50% of the Note, and cash of US$253,014 was paid, which represented US$250,000 of principal and US$3,014 of interest (total payment of A$380,224). The investor exercised their option to receive the remaining 50% in ADSs on 20 December 2023, which resulted in 591,697 ADS to be issued. On 19 June 2024, 591,697 ADSs representing 5,916,970 ordinary shares were issued at a price of A$0.0643 per ordinary share. Subsequent to 30 June 2024, the investor was unable to meet their obligations for transfer of the shares and on 2 July 2024 the share allocation was cancelled and remains recognised as unissued equity as at 31 December 2025.

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 15. Reserves

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| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br> 2025<br>$ | June<br>2025<br>$ |
| Foreign currency translation reserve | (1633404) | (773511) |
| Share-based payments reserve | 6737860 | 3873198 |
|  | 5104456 | 3099687 |

---

Foreign currency reserve

The reserve is used to recognise exchange differences arising from translation of the financial statements of foreign operations to Australian dollars.

Share-based payments reserve

The reserve is used to recognise the value of equity benefits provided to employees and directors as part of their remuneration, and other parties as part of their compensation for services.

Share based payments reserve for Employee Share Option Plan

During the half year there were no issues under the Employee Share Option Plan

#### Note 16. Dividends
There were no dividends paid, recommended or declared during the current or previous financial half-year.

#### Note 17. Loss per share

---

| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br>2025<br>$ | December<br> 2024<br>$ |
| Loss after income tax attributable to the owners of Kazia Therapeutics Limited | (12552490) | (10453811) |
|  | Number | Number |
| Weighted average number of ordinary shares used in calculating basic loss per share | 1560213259 | 425157427 |
| Weighted average number of ordinary shares used in calculating diluted loss per share | 1560213259 | 425157427 |
|  | Cents | Cents |
| Basic loss per share | (0.805) | (2.459) |
| Diluted loss per share | (0.805) | (2.459) |

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>Notes to the financial statements<br>31 December 2025 | ![](g45630g52z59.jpg) |

---

#### Note 18. Reconciliation of loss after income tax to net cash used in operating activities

---

| | | |
|:---|:---|:---|
|  | Consolidated | Consolidated |
|  | December<br> 2025 | December<br> 2024 |
|  | $ | $ |
| Loss after income tax benefit for the half-year) |  |  |
| Adjustments for: |  |  |
| Amortisation |  |  |
| Share-based payments expense |  |  |
| Foreign exchange differences) |  |  |
| Fair value (gain)/loss on financial liabilities at fair value through profit or loss |  |  |
| Gain on contingent consideration) |  |  |
| Contingent consideration interest |  |  |
| Change in operating assets and liabilities: |  |  |
| (Increase) / Decrease trade and other receivables |  |  |
| Decrease in other assets |  |  |
| Decrease in borrowings) |  |  |
| Decrease in trade and other payables) |  |  |
| Decrease in deferred tax liabilities) |  |  |
| Increase in employee benefits provisions |  |  |
| Net cash used in operating activities) |  |  |

---

#### Note 19. Events after the reporting period
No matter or circumstance has arisen since 31 December 2025 that has significantly affected, or may significantly affect the Consolidated entity's operations, the results of those operations, or the Consolidated entity's state of affairs in future financial years.

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| | |
|:---|:---|
| Kazia Therapeutics Limited<br>**Directors' declaration**<br>31 December 2025 | ![](g45630g52z59.jpg) |

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In the directors' opinion:

• the attached financial statements and notes comply with the Corporations Act 2001, Australian Accounting Standard AASB 134 'Interim Financial Reporting', the Corporations Regulations 2001 and other mandatory professional reporting requirements;

• the attached financial statements and notes give a true and fair view of the Consolidated entity's financial position as at 31 December 2025 and of its performance for the financial half-year ended on that date; and

• there are reasonable grounds to believe that the Consolidated entity will be able to pay its debts as and when they become due and payable.

Signed in accordance with a resolution of directors made pursuant to section 303(5)(a) of the Corporations Act 2001.

On behalf of the directors

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| |
|:---|
| /s/ Steven Coffey |
| Steven Coffey<br>Director |
| 16 March 2026<br>Sydney |

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| | | |
|:---|:---|:---|
| ![](g45630g79v93.jpg) | Tel: +61 2 9251 4100<br>Fax: +61 2 9240 9821<br>www.bdo.com.au | Parkline Place<br>Level 25, 252 Pitt Street<br>Sydney NSW 2000<br>Australia |

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#### INDEPENDENT AUDITOR'S REVIEW REPORT
To the members of Kazia Therapeutics Limited

#### Report on the Half-Year Financial Report

#### Conclusion
We have reviewed the half-year financial report of Kazia Therapeutics Limited (the Company) and its subsidiaries (the Group), which comprises the consolidated statement of financial position as at 31 December 2025, the consolidated statement of profit or loss and other comprehensive income, the consolidated statement of changes in equity and the consolidated statement of cash flows for the half-year ended on that date, material accounting policy information and other explanatory information, and the directors' declaration.

Based on our review, which is not an audit, we have not become aware of any matter that makes us believe that the accompanying half-year financial report of the Group does not comply with the Corporations Act 2001 including:

i. Giving a true and fair view of the Group's financial position as at 31 December 2025 and of its financial performance for the half-year ended on that date; and

ii. Complying with Accounting Standard AASB 134 Interim Financial Reporting and the Corporations Regulations 2001.

#### Basis for conclusion
We conducted our review in accordance with ASRE 2410 Review of a Financial Report Performed by the Independent Auditor of the Entity. Our responsibilities are further described in the Auditor's Responsibilities for the Review of the Financial Report section of our report. We are independent of the Group in accordance with the auditor independence requirements of the Corporations Act 2001 and the ethical requirements of the Accounting Professional and Ethical Standards Board's APES 110 Code of Ethics for Professional Accountants (including Independence Standards) (the Code) that are relevant to the audit of the annual financial report in Australia. We have also fulfilled our other ethical responsibilities in accordance with the Code.

We confirm that the independence declaration required by the Corporations Act 2001 which has been given to the directors of the Company, would be the same terms if given to the directors as at the time of this auditor's review report.

#### Responsibility of the directors for the financial report
The directors of the Company are responsible for the preparation of the half-year financial report that gives a true and fair view in accordance with Australian Accounting Standards and the Corporations Act 2001 and for such internal control as the directors determine is necessary to enable the preparation of the half-year financial report that gives a true and fair view and is free from material misstatement, whether due to fraud or error.

BDO Audit Pty Ltd ABN 33 134 022 870 is a member of a national association of independent entities which are all members of BDO International Ltd, a UK company limited by guarantee, and form part of the international BDO network of independent member firms. Liability limited by a scheme approved under Professional Standards Legislation.

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![](g45630g79v93.jpg)

#### Auditor's responsibility for the review of the financial report
Our responsibility is to express a conclusion on the half-year financial report based on our review. ASRE 2410 requires us to conclude whether we have become aware of any matter that makes us believe that the half-year financial report is not in accordance with the Corporations Act 2001 including giving a true and fair view of the Group's financial position as at 31 December 2025 and its financial performance for the half-year ended on that date and complying with Accounting Standard AASB 134 Interim Financial Reporting and the Corporations Regulations 2001.

A review of a half-year financial report consists of making enquiries, primarily of persons responsible for financial and accounting matters, and applying analytical and other review procedures. A review is substantially less in scope than an audit conducted in accordance with Australian Auditing Standards and consequently does not enable us to obtain assurance that we would become aware of all significant matters that might be identified in an audit. Accordingly, we do not express an audit opinion.

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| |
|:---|
| BDO Audit Pty Ltd |
| /s/ Gareth Few |
| Gareth Few<br>Director |

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Sydney, 16 March 2026