# EDGAR Filing Document

**Accession Number:** 0001043961
**File Stem:** 0001104659-26-006653
**Filing Date:** 2026-1
**Character Count:** 22932
**Document Hash:** 5ca80f872cc68b8e606c3571ecfa0b91
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-26-006653.hdr.sgml**: 20260126

**ACCESSION NUMBER**: 0001104659-26-006653

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 17

**FILED AS OF DATE**: 20260126

**DATE AS OF CHANGE**: 20260126

**EFFECTIVENESS DATE**: 20260126

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Precipio, Inc.
- **CENTRAL INDEX KEY:** 0001043961
- **STANDARD INDUSTRIAL CLASSIFICATION:** LABORATORY ANALYTICAL INSTRUMENTS [3826]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 911789357
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-292961
- **FILM NUMBER:** 26561306

**BUSINESS ADDRESS:**
- **STREET 1:** 4 SCIENCE PARK
- **CITY:** NEW HAVEN
- **STATE:** CT
- **ZIP:** 06511
- **BUSINESS PHONE:** 203 787 7888

**MAIL ADDRESS:**
- **STREET 1:** 4 SCIENCE PARK
- **CITY:** NEW HAVEN
- **STATE:** CT
- **ZIP:** 06511

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** TRANSGENOMIC INC
- **DATE OF NAME CHANGE:** 20000119

**As filed with the Securities and Exchange Commission on January 26, 2026**

**Registration No. 333-**

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM S-8**

**REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933**

**Precipio, Inc.**

(Exact name of registrant as specified in its charter)

---

| | |
|:---|:---|
| **Delaware** | **91-1789357** |
| (State or other jurisdiction of<br> incorporation or organization) | (I.R.S. Employer<br> Identification No.) |

---

---

| | |
|:---|:---|
| **4 Science Park, New Haven, CT** | **06511** |
| (Address of Principal Executive Offices) | (Zip Code) |

---

**Precipio, Inc. Amended and Restated 2017 Stock Option and Incentive Plan**

(Full Title of the Plans)

**Ilan Danieli**

**Chief Executive Officer**

**4 Science Park, New Haven, CT 06511**

(Name and address of agent for service)

(203) 787-7888

(Telephone number, including area code, of agent for service)

**Copy to:**

**Stephen M. Davis, Esq.**

**Goodwin Procter LLP**

**620 Eighth Avenue**

**New York, NY**

**(212) 813-8800**

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

Large accelerated filer ◻ Accelerated filer ◻ <br> Non-accelerated filer ⌧ Smaller reporting company ⌧ <br> Emerging growth company ◻

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ◻

**EXPLANATORY NOTE**

This Registration Statement on Form S-8 (the "Registration Statement") is being filed by Precipio, Inc. (the "Registrant") to register additional securities issuable pursuant to the Registrant's Amended and Restated 2017 Stock Option and Incentive Plan (the "Plan") and consists of only those items required by General Instruction E to Form S-8. Pursuant to certain provisions of the Plan (referred to as the "evergreen provisions"), the number of shares of the Registrant's common stock, $0.01 par value per share (the "Common Stock"), that are available for award grant purposes under the Plan, is automatically increased each year in accordance with a formula set forth in the Plan. Pursuant to the Plan's evergreen provisions, the additional securities registered hereby include 89,045 shares of Common Stock that were automatically added to the Plan, effective January 1, 2026.

In accordance with General Instruction E to Form S-8, the contents of the earlier registration statements on Form S-8 ([File No. 333-284316](https://www.sec.gov/Archives/edgar/data/1043961/000110465925004086/tm253587d1_s-8.htm), [File No. 333-278385](https://www.sec.gov/Archives/edgar/data/1043961/000110465924041153/tm2410202d1_s8.htm), [File No. 333-271002](https://www.sec.gov/Archives/edgar/data/1043961/000110465923039240/tm2310893d1_s8.htm), [File No. 333-222819](https://www.sec.gov/Archives/edgar/data/1043961/000114420418005194/tv484555_s8.htm) and [File No. 333-221804](https://www.sec.gov/Archives/edgar/data/1043961/000119312517355701/d476995ds8.htm)), as filed with the Securities and Exchange Commission (the "Commission") on January 16, 2025, March 29, 2024, March 30, 2023, February 1, 2018 and November 29, 2017, respectively are effective and are incorporated herein by reference, except as otherwise set forth herein.

**Part II**

**INFORMATION REQUIRED IN THE REGISTRATION STATEMENT**

**Item 3. Incorporation of Documents by Reference.**

The following documents have been previously filed by the Registrant with the Commission and are hereby incorporated by reference into this Registration Statement and shall be deemed a part hereof:

&nbsp;&nbsp;&nbsp;&nbsp;(a) [The Registrant's Annual Report on Form 10-K for the year ended December 31, 2024, filed with the Commission on March 27, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000155837025003817/prpo-20241231x10k.htm) ;

&nbsp;&nbsp;&nbsp;&nbsp;(b) [The Registrant's Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the Commission on May 14, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000155837025007776/prpo-20250331x10q.htm) ;

&nbsp;&nbsp;&nbsp;&nbsp;(c) [The Registrant's Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2025, filed with the Commission on August 13, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000155837025011390/prpo-20250630x10q.htm) ;

&nbsp;&nbsp;&nbsp;&nbsp;(d) [The Registrant's Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2025, filed with the Commission on November 14, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000110465925112601/prpo-20250930x10q.htm) ;

&nbsp;&nbsp;&nbsp;&nbsp;(e) The Registrant's Current Reports on Form 8-K, filed with the Commission on [January 21, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000110465925004875/tm253755d1_8k.htm) , [April 10, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000110465925033457/tm2511994d1_8k.htm) , [June 17, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000110465925060236/tm2518241d1_8k.htm) , [September 3, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000110465925086995/tm2525140d1_8k.htm) and [December 29, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1043961/000110465925124902/tm2534444d1_8k.htm) .

&nbsp;&nbsp;&nbsp;&nbsp;(f) The description of the Registrant's Common Stock contained in the Registrant's registration
statement on [Form 8-A filed with the Commission on June 29, 2017](https://www.sec.gov/Archives/edgar/data/1043961/000114420417034976/v470084_8a12b.htm) , including any amendments or reports filed for the purposes
of updating this description; and

All reports and other documents subsequently filed with the Commission by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934, as amended, prior to the filing of a post-effective amendment which indicates that all securities offered have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement and to be a part hereof from the date of filing of such documents, excluding any information furnished under Item 7.01 or Item 2.02 of any Current Report on Form 8-K (and corresponding information furnished under Item 9.01 or included as an exhibit thereto). Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for the purposes of this Registration Statement to the extent that a statement contained herein or in any other subsequently filed document that also is or is deemed to be incorporated by reference herein modifies or replaces such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.

**Item 8. Exhibits.**

---

| | |
|:---|:---|
| **Exhibit No.** | **Description** |
| [3.1](https://www.sec.gov/Archives/edgar/data/1043961/000114420417035085/v470106_ex3-1.htm) | [Third Amended and Restated Certificate of Incorporation, as amended (incorporated by reference to Exhibit 3.1 of the Registrant's Form 8-K filed on June 30, 2017).](https://www.sec.gov/Archives/edgar/data/1043961/000114420417035085/v470106_ex3-1.htm) |
| [3.2](https://www.sec.gov/Archives/edgar/data/1043961/000114420417035085/v470106_ex3-2.htm) | [Amended and Restated Bylaws (incorporated by reference to Exhibit 3.2 of the Registrant's Form 8-K filed on June 30, 2017).](https://www.sec.gov/Archives/edgar/data/1043961/000114420417035085/v470106_ex3-2.htm) |
| [3.3](https://www.sec.gov/Archives/edgar/data/1043961/000114420417035085/v470106_ex3-3.htm) | [Certificate of Elimination (incorporated by reference to Exhibit 3.3 of the Company's Form 8-K filed on June 30, 2017).](https://www.sec.gov/Archives/edgar/data/1043961/000114420417035085/v470106_ex3-3.htm) |
| [3.4](https://www.sec.gov/Archives/edgar/data/1043961/000119312517274394/d449841dex31.htm) | [Certificate of Designation for Series B Preferred Stock (incorporated by reference to Exhibit 3.1 of the Company's Form 8-K filed on August 31, 2017).](https://www.sec.gov/Archives/edgar/data/1043961/000119312517274394/d449841dex31.htm) |
| [3.5](https://www.sec.gov/Archives/edgar/data/1043961/000119312517332004/d486748dex31.htm) | [Certificate of Designation for Series C Preferred Stock (incorporated by reference to Exhibit 3.1 of the Company's Form 8-K filed on November 3, 2017).](https://www.sec.gov/Archives/edgar/data/1043961/000119312517332004/d486748dex31.htm) |
| [3.6](https://www.sec.gov/Archives/edgar/data/1043961/000155837019003368/ex-3d1.htm) | [Certificate of Amendment to the Third Amended and Restated Certificate of Incorporation, dated April 25, 2019 (incorporated by reference to Exhibit 3.1 of the Company's Form 8-K filed on April 26, 2019).](https://www.sec.gov/Archives/edgar/data/1043961/000155837019003368/ex-3d1.htm) |
| [3.7](https://www.sec.gov/Archives/edgar/data/1043961/000110465923102859/tm2326654d1_ex3-1.htm) | [Certificate of Amendment to the Third Amended and Restated Certificate of Incorporation, dated 21 September 21, 2023 (incorporated by reference to Exhibit 3.1 of the Company's Form 8-K filed on September 21, 2023).](https://www.sec.gov/Archives/edgar/data/1043961/000110465923102859/tm2326654d1_ex3-1.htm) |
| [5.1\*](tm264098d1_ex5-1.htm) | [Opinion of Goodwin Procter LLP.](tm264098d1_ex5-1.htm) |
| [23.1\*](tm264098d1_ex23-1.htm) | [Consent of Marcum LLP, Independent Registered Public Accounting Firm.](tm264098d1_ex23-1.htm) |
| [23.2\*](tm264098d1_ex5-1.htm) | [Consent of Goodwin Procter LLP (included in Exhibit 5.1).](tm264098d1_ex5-1.htm) |
| [24.1\*](#v1) | [Power of Attorney (included on signature page).](#v1) |
| [99.1](https://www.sec.gov/Archives/edgar/data/1043961/000114036121014971/nc10023643x1_def14a.htm) | [Amended and Restated 2017 Stock Option and Incentive Plan (incorporated by reference to Annex B of the Registrant's Definitive Proxy Statement on Schedule 14A filed on April 29, 2021).](https://www.sec.gov/Archives/edgar/data/1043961/000114036121014971/nc10023643x1_def14a.htm) |
| [107\*](tm264098d1_ex-filingfees.htm) | [Filing Fee Table.](tm264098d1_ex-filingfees.htm) |

---

\* Filed herewith.

**SIGNATURES**

Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of New Haven, State of Connecticut, on the 26th day of January 2026.

---

| | |
|:---|:---|
| **Precipio, Inc.** | **Precipio, Inc.** |
| By: | /s/ Ilan Danieli |
|  | Ilan Danieli |
|  | Chief Executive Officer<br> (Principal Executive Officer) |

---

**POWER OF ATTORNEY AND SIGNATURES**

KNOW ALL BY THESE PRESENT, that each individual whose signature appears below hereby constitutes and appoints each of Ilan Danieli and Matthew Gage as such person's true and lawful attorney-in-fact and agent with full power of substitution and resubstitution, for such person in such person's name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement on Form S-8, and to file the same, with all exhibits thereto, and all documents in connection therewith, with the Securities and Exchange Commission granting unto each said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as such person might or could do in person, hereby ratifying and confirming all that any said attorney-in-fact and agent, or any substitute or substitutes of any of them, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following person in the capacities and on the date indicated.

---

| | | |
|:---|:---|:---|
| **Signature** | **Title** | **Date** |
| /s/ Ilan Danieli | Director and Chief Executive Officer<br> *(Principal Executive Officer)* | January 26, 2026 |
| **Ilan Danieli** | Director and Chief Executive Officer<br> *(Principal Executive Officer)* | January 26, 2026 |
| <br> /s/ Matthew Gage | <br> Interim Chief Financial Officer<br> *(Principal Financial and Accounting Officer)* | January 26, 2026 |
| **Matthew Gage** | <br> Interim Chief Financial Officer<br> *(Principal Financial and Accounting Officer)* | January 26, 2026 |
| <br> /s/ Richard Sandberg | <br> Chairman of the Board of Directors | January 26, 2026 |
| **Richard Sandberg** | <br> Chairman of the Board of Directors | January 26, 2026 |
| <br> /s/ Kathleen Laporte | Director | January 26, 2026 |
| **Kathleen Laporte**<br>/s/ Ronald Andrews | Director | January 26, 2026 |
| **Ronald Andrews** | Director | January 26, 2026 |
| <br> /s/ Christina Valauri. | Director | January 26, 2026 |
| **Christina Valuari** | Director | January 26, 2026 |
| <br> /s/ Jeffrey Cossman, M.D. | Director | January 26, 2026 |
| **Jeffrey Cossman, M.D.** | Director | January 26, 2026 |
| <br> /s/ David Cohen | Director | January 26, 2026 |
| **David Cohen** | Director | January 26, 2026 |

---

## Exhibit 5.1

**Exhibit 5.1**

![](tm264098d1_ex5-1img01.jpg)

January 26, 2026

Precipio, Inc.

4 Science Park

New Haven, CT 06511

Re: <u>Securities Being Registered under Registration Statement on Form S-8</u>

We have acted as counsel to you in connection with your filing of a Registration Statement on Form S-8 (the "Registration Statement") pursuant to the Securities Act of 1933, as amended (the "Securities Act"), on or about the date hereof relating to an aggregate of 89,045 shares (the "Shares") of Common Stock, $0.01 par value per share ("Common Stock"), of Precipio, Inc., a Delaware corporation (the "Company"), that may be issued pursuant to the Precipio, Inc. Amended and Restated 2017 Stock Option and Incentive Plan (the "Plan").

We have reviewed such documents and made such examination of law as we have deemed appropriate to give the opinions set forth below. We have relied, without independent verification, on certificates of public officials and, as to matters of fact material to the opinion set forth below, on certificates of officers of the Company.

The opinion set forth below is limited to the Delaware General Corporation Law.

For purposes of the opinion set forth below, we have assumed that no event occurs that causes the number of authorized shares of Common Stock available for issuance by the Company to be less than the number of then unissued Shares.

Based on the foregoing, we are of the opinion that the Shares have been duly authorized and, upon issuance and delivery against payment therefor in accordance with the terms of the Plan, will be validly issued, fully paid and nonassessable.

This opinion letter and the opinion it contains shall be interpreted in accordance with the Core Opinion Principles as published in 74 *Business Lawyer* 815 (Summer 2019).

We hereby consent to the inclusion of this opinion as Exhibit 5.1 to the Registration Statement. In giving our consent, we do not admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations thereunder.

---

| |
|:---|
| Very truly yours, |
| /s/ Goodwin Procter LLP |
| GOODWIN PROCTER LLP |

---

## Exhibit 23.1

**Exhibit 23.1**

![](tm264098d1_ex23-1img01.jpg)

**<u>INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM'S CONSENT</u>**

We consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 27, 2025, which includes an explanatory paragraph as to Precipio, Inc.'s ability to continue as a going concern, relating to the consolidated financial statements appearing in the Annual Report on Form 10-K of Precipio, Inc. for the year ended December 31, 2024.

Very truly yours,

![](tm264098d1_ex23-1img02.jpg)

Marcum LLP<br> New Haven, CT<br> January 26, 2026

## Ex-Filing

?xml version='1.0' encoding='ASCII'? EX-FILING FEES

---

| |
|:---|
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Calculation of Filing Fee Tables**  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **S-8**  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Precipio, Inc.**  |

---

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| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Security Type**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Security Class Title**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Fee Calculation Rule**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Amount Registered**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Proposed Maximum Offering Price Per Unit**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Maximum Aggregate Offering Price**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Fee Rate**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Amount of Registration Fee**  |
| 1 | Equity | Precipio, Inc. Amended and Restated 2017 Stock Option and Incentive Plan Common stock, $0.01 par value per share | 457(a) | 89045 | $24.55 | $2186054.75 | 0.0001381 | $301.89 |
| Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: |  | $2186054.75  |  | $301.89  |
| Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  |  |  |  | $0.00  |
| Net Fee Due:  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  |  |  |  | $301.89  |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Offering Note** <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <sup>1</sup> Note 1.a Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional shares of the Registrant's common stock that become issuable by reason of any stock dividend, stock split, recapitalization, or other similar transaction effected that results in an increase to the number of outstanding shares of the Registrant's common stock. Note 1.b Represents 89,045 shares of Common Stock that were automatically added to the Plan, effective January 1, 2026. Other shares of Common Stock available for issuance under the Plan were previously registered on registration statements on Form S-8 filed with the Securities and Exchange Commission on January 16, 2025 (File No. 333-284316), March 29, 2024 (File No. 333-278385), March 30, 2023 (File No. 333-271002), February 1, 2018 (File No. 333-222819) and November 29, 2017 (File No. 333-221804). Note 1.c Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and (h) of the Securities Act, and based on the average of the high and low sale prices of the Registrant's Common Stock, as quoted on The Nasdaq Capital Market, on January 23, 2026

---

| | |
|:---|:---|
| | |
| **Rule 457(p)** | **Rule 457(p)** |
| Fee Offset Claims | N/A |
| Fee Offset Sources | N/A |

---