# EDGAR Filing Document

**Accession Number:** 0001554859
**File Stem:** 0000950103-26-000624
**Filing Date:** 2026-1
**Character Count:** 8156
**Document Hash:** dc9289e5b35579ffe2eb16e12d5e333f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000950103-26-000624.hdr.sgml**: 20260116

**ACCESSION NUMBER**: 0000950103-26-000624

**CONFORMED SUBMISSION TYPE**: S-8 POS

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20260116

**DATE AS OF CHANGE**: 20260116

**EFFECTIVENESS DATE**: 20260116

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Semler Scientific, Inc.
- **CENTRAL INDEX KEY:** 0001554859
- **STANDARD INDUSTRIAL CLASSIFICATION:** ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 261367393
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8 POS
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-283009
- **FILM NUMBER:** 26540296

**BUSINESS ADDRESS:**
- **STREET 1:** 51 E CAMPBELL AVE
- **STREET 2:** SUITE 107-D
- **CITY:** CAMPBELL
- **STATE:** CA
- **ZIP:** 95008
- **BUSINESS PHONE:** 8777744211

**MAIL ADDRESS:**
- **STREET 1:** 51 E CAMPBELL AVE
- **STREET 2:** SUITE 107-D
- **CITY:** CAMPBELL
- **STATE:** CA
- **ZIP:** 95008

**As filed with the Securities and Exchange Commission on January 16, 2026**

**Registration No. 333-285470**

**Registration No. 333-283009**

**Registration No. 333-263341**

**Registration No. 333-207779**

**Registration No. 333-198891**

**Registration No. 333-198275**

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**POST-EFFECTIVE AMENDMENT NO. 1 (No. 333-285470)**

**POST-EFFECTIVE AMENDMENT NO. 1 (No. 333-283009)**

**POST-EFFECTIVE AMENDMENT NO. 1 (No. 333-263341)**

**POST-EFFECTIVE AMENDMENT NO. 1 (No. 333-207779)**

**POST-EFFECTIVE AMENDMENT NO. 1 (No. 333-198891)**

**POST-EFFECTIVE AMENDMENT NO. 1 (No. 333-198275)**

**<br> TO**

**FORM S-8**

**REGISTRATION STATEMENT UNDER**

**THE SECURITIES ACT OF 1933**

**Semler Scientific, Inc.**

(Exact Name of Registrant as Specified in its Charter)

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| | | |
|:---|:---|:---|
| **Delaware** |  | **26-1367393** |
| (State or Other Jurisdiction of <br> Incorporation or Organization) |  | (I.R.S. Employer <br> Identification No.) |
|  | **51 E. Campbell Avenue, Suite 107-D<br> Campbell, California 95008** |  |
| (Address of Principal Executive Offices) | (Address of Principal Executive Offices) | (Address of Principal Executive Offices) |

---

**Semler Scientific, Inc. 2024 Stock Option and Incentive Plan<br> Semler Scientific, Inc. 2014 Stock Incentive Plan<br> Semler Scientific, Inc. 2007 Key Person Stock Option Plan**<br> (Full Title of the Plan)

**Brian Logan Beirne<br> Strive, Inc.<br> Chief Legal Officer**<br>**200 Crescent Court, Suite 1400**<br>**Dallas, TX 75201** <br>**(855) 427-7360**<br> (Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent For Service)<br>***Copies to:***<br>**Derek Dostal**<br>**Evan Rosen<br> Adam Kaminsky**<br>**Davis Polk & Wardwell LLP**<br>**450 Lexington Avenue**<br>**New York, New York 10017**<br>**(212) 450-4000**<br>

**Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer, " "smaller reporting company" and "emerging growth company" in Rule 12b-2 of the Exchange Act.** 

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| | |
|:---|:---|
| **Large accelerated filer** ☐ | **Accelerated filer** ☐ |
| **Non-accelerated filer** ☒ | **Smaller reporting company** ☒ |
|  | **Emerging Growth Company ☐** |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

**EXPLANATORY NOTE**

These Post-Effective Amendments (collectively, the "Post-Effective Amendments") relate to the following Registration Statements of Semler Scientific, Inc., a Delaware corporation (the "Registrant") on Form S-8 (collectively, the "Registration Statements"):

&nbsp;&nbsp;&nbsp;&nbsp;1. Registration Statement No. [333-285470](https://www.sec.gov/Archives/edgar/data/1554859/000110465925019241/tm257507d1_s8.htm) ,
registering 382,259 shares of the Registrant's common stock, par value $0.001 per share (the "Shares"), issuable pursuant
to the Registrant's 2024 Stock Option and Incentive Plan (the "2024 Plan"), filed with the Securities and Exchange Commission
(the "SEC") on February 28, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;2. Registration Statement No. [333-283009](https://www.sec.gov/Archives/edgar/data/1554859/000110465924114374/tm2427203d1_s8.htm) ,
registering 3,172,399 Shares issuable pursuant to the 2024 Plan, filed with the SEC on November 5, 2024.

&nbsp;&nbsp;&nbsp;&nbsp;3. Registration Statement No. [333-263341](https://www.sec.gov/Archives/edgar/data/1554859/000110465922031044/tm228395d1_s8.htm) ,
registering 1,176,563 Shares issuable pursuant to the Registrant's 2014 Stock Incentive Plan (the "2014 Plan"), filed
with the SEC on March 7, 2022.

&nbsp;&nbsp;&nbsp;&nbsp;4. Registration Statement No. [333-207779](https://www.sec.gov/Archives/edgar/data/1554859/000157104915008764/t1502473_s8.htm) ,
registering 1,688,640 Shares issuable pursuant to the 2014 Plan, filed with the SEC on November 3, 2015.

&nbsp;&nbsp;&nbsp;&nbsp;5. Registration Statement No. [333-198891](https://www.sec.gov/Archives/edgar/data/1554859/000157104914004766/t1401822_s8.htm) ,
registering 450,000 Shares issuable pursuant to the 2014 Plan, filed with the SEC on September 23, 2014.

&nbsp;&nbsp;&nbsp;&nbsp;6. Registration Statement No. [333-198275](https://www.sec.gov/Archives/edgar/data/1554859/000157104914004157/t1401615_s8.htm) ,
registering 407,500 Shares issuable pursuant to the Registrant's 2007 Key Person Stock Option Plan, filed with the SEC on August
20, 2014.

On January 16, 2026, pursuant to the terms of that certain Agreement and Plan of Merger, dated as of September 22, 2025 (as amended by that certain Amendment Letter dated as of December 3, 2025, the "Merger Agreement"), by and between the Registrant and Strive, Inc., a Nevada corporation ("Strive"), the Registrant merged with and into Strive Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Strive, with the Registrant surviving as a wholly owned subsidiary of Strive.

In connection with the Merger, the offerings of securities pursuant to the Registration Statements have been terminated. In accordance with the undertakings made by the Registrant in Part II of each Registration Statement to remove from registration, by means of a post-effective amendment, any of the securities registered pursuant to the Registration Statements which remain unsold at the termination of the offerings, the Registrant hereby terminates the effectiveness of each Registration Statement and removes from registration all Shares registered under each Registration Statement that remain unsold as of the date hereof. Each Registration Statement is hereby amended, as appropriate, to reflect the deregistration of such securities. After giving effect to these Post-Effective Amendments, there will be no remaining securities registered by the Registrant pursuant to the Registration Statements.

**SIGNATURES**

Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused these Post-Effective Amendments to the Registration Statements on Form S-8 to be signed on its behalf by the undersigned, thereunto duly authorized, in the city of Campbell, State of California, on the 16th day of January, 2026

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| | | |
|:---|:---|:---|
| **SEMLER SCIENTIFIC, INC.** | **SEMLER SCIENTIFIC, INC.** | **SEMLER SCIENTIFIC, INC.** |
| By: | /s/ Brian Logan Beirne | /s/ Brian Logan Beirne |
|  | Name: | Brian Logan Beirne |
|  | Title: | Secretary |

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Pursuant to Rule 478 under the Securities Act of 1933, as amended, no other person is required to sign these Post-Effective Amendments.