# EDGAR Filing Document

**Accession Number:** 0001761612
**File Stem:** 0001104659-26-075451
**Filing Date:** 2026-6
**Character Count:** 9451
**Document Hash:** a88d014a1279ae27a665960d6f49d564
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-26-075451.hdr.sgml**: 20260618

**ACCESSION NUMBER**: 0001104659-26-075451

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 12

**CONFORMED PERIOD OF REPORT**: 20260617

**ITEM INFORMATION**: Submission of Matters to a Vote of Security Holders

**FILED AS OF DATE**: 20260618

**DATE AS OF CHANGE**: 20260618

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** BICYCLE THERAPEUTICS PLC
- **CENTRAL INDEX KEY:** 0001761612
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** X0
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38916
- **FILM NUMBER:** 261100497

**BUSINESS ADDRESS:**
- **STREET 1:** BLOCKS A & B, PORTWAY BUILDING
- **STREET 2:** GRANTA PARK, GREAT ABINGTON
- **CITY:** CAMBRIDGE
- **STATE:** X0
- **ZIP:** CB21 6GS
- **BUSINESS PHONE:** 011441223261503

**MAIL ADDRESS:**
- **STREET 1:** BLOCKS A & B, PORTWAY BUILDING
- **STREET 2:** GRANTA PARK, GREAT ABINGTON
- **CITY:** CAMBRIDGE
- **STATE:** X0
- **ZIP:** CB21 6GS

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** BICYCLE THERAPEUTICS plc
- **DATE OF NAME CHANGE:** 20190530

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** BICYCLE THERAPEUTICS Ltd
- **DATE OF NAME CHANGE:** 20181212

?xml version='1.0' encoding='ASCII'?

**UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934**

**June 17, 2026**

Date of Report (Date of earliest event reported)

**Bicycle Therapeutics plc**

(Exact name of registrant as specified in its charter)

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| | | |
|:---|:---|:---|
| **England and Wales** | **001-38916** | **Not applicable** |
| (State or other jurisdiction <br> of incorporation) | (Commission<br> File Number) | (IRS Employer<br> Identification No.) |

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| | |
|:---|:---|
| &nbsp;&nbsp;**Blocks A & B, Portway Building** **,<br> Granta Park Great Abington, Cambridge<br> United Kingdom** | &nbsp;&nbsp;**CB21 6GS** |
| &nbsp;&nbsp;(Address of principal executive offices) | &nbsp;&nbsp;(Zip Code) |

---

Registrant's telephone number, including area code: **+44** **1223 261503**

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

◻ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) <br>

◻ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) <br>

◻ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) <br>

◻ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

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| | | |
|:---|:---|:---|
| &nbsp;&nbsp;**Title of each class** | &nbsp;&nbsp;**Trading Symbol (s)** | &nbsp;&nbsp;**Name of each exchange on which registered** |
| &nbsp;&nbsp;Ordinary shares, nominal value £0.01 per share | &nbsp;&nbsp;n/a | &nbsp;&nbsp;The Nasdaq Stock Market LLC\* |
| &nbsp;&nbsp;American Depositary Shares, each representing one ordinary share, nominal value £0.01 per share | &nbsp;&nbsp;BCYC | &nbsp;&nbsp;The Nasdaq Stock Market LLC |

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**\*** Not for trading, but only in connection with the listing of the American Depositary Shares on The Nasdaq Stock Market LLC.

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company ◻

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ◻

**Item 5.07 Submission of Matters to a Vote of Security Holders** 

Bicycle Therapeutics plc (the "Company") held its annual general meeting of shareholders (the "AGM") on June 17, 2026. Each of the proposals set forth below were voted on and duly passed on a poll at the AGM. Detailed descriptions of these proposals and of the voting procedures applied at the AGM are contained in the Company's definitive proxy statement on Schedule 14A filed with the Securities and Exchange Commission on April 22, 2026.

There were 49,696,908 ordinary shares of the Company represented in person or by proxy at the AGM, constituting approximately 98.64% of the issued and outstanding ordinary shares on June 17, 2026. Proxy appointments which gave the Chairman of the meeting discretion have been included in the "For" total. In accordance with the terms of the deposit agreement by and among the Company, Citibank, N.A., as depositary, and holders and beneficial owners of American Depositary Shares ("ADSs") dated May 28, 2019, holders of ADSs who did not provide the depositary bank with voting instructions on or before the specified deadline were deemed to have instructed the depositary to give a discretionary proxy to a person designated by the Company to vote the underlying ordinary shares at the AGM and the voting results below reflect that designation. A vote withheld/abstain is not a vote in law and is not counted in the calculation of votes for or against a resolution.

**<u>Ordinary Resolutions</u>**

**Proposal 1 – To re-elect as a director Felix Baker**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 46171302 |  | 3364113 |  | 161493 |

---

**Proposal 2 – To re-elect as a director Hervé Hoppenot**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 49284459 |  | 250669 |  | 161780 |

---

**Proposal 3 – To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the Company's definitive proxy statement**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 48748743 |  | 785032 |  | 163133 |

---

**Proposal 4 – To ratify the appointment of PricewaterhouseCoopers LLP, a limited liability partnership organized under the laws of England, as the Company's independent registered public accounting firm for the year ending December 31, 2026**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 49445128 |  | 232627 |  | 19153 |

---

**Proposal 5 – To re-appoint PricewaterhouseCoopers LLP, a limited liability partnership organized under the laws of England, as the Company's U.K. statutory auditors, to hold office until the conclusion of the next annual general meeting of shareholders**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 49441337 |  | 235008 |  | 20563 |

---

**Proposal 6 – To authorize the Audit Committee of the Company's Board of Directors to determine the Company's U.K. statutory auditors' remuneration for the year ending December 31, 2026**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 49493240 |  | 47269 |  | 156399 |

---

**Proposal 7 – To receive and adopt the Company's U.K. statutory annual accounts and reports for the year ended December 31, 2025.**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 49138590 |  | 553781 |  | 4537 |

---

**Proposal 8 – To approve the directors' remuneration report for the year ended December 31, 2025, which report is set forth in the Company's definitive proxy statement (excluding the directors' remuneration policy)**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 48741517 |  | 792394 |  | 162997 |

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**Proposal 9 – To approve the directors' remuneration policy, which policy is set forth in the Company's definitive proxy statement, and which will take effect immediately after the end of the AGM**

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **For** | **For** | **Against** | **Against** | **Vote Withheld/Abstain** | **Vote Withheld/Abstain** |
|  | 48238031 |  | 1293722 |  | 165155 |

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**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | | |
|:---|:---|:---|
| Date: June 18, 2026 | **BICYCLE THERAPEUTICS PLC** | **BICYCLE THERAPEUTICS PLC** |
|  | By: | /s/ Travis Thompson |
|  | Name: | Travis Thompson |
|  | Title: | Chief Financial Officer |

---