# EDGAR Filing Document

**Accession Number:** 0001287098
**File Stem:** 0001104659-25-083112
**Filing Date:** 2025-8
**Character Count:** 26602
**Document Hash:** a633576ae635d379ddeee340de3614a1
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-083112.hdr.sgml**: 20250826

**ACCESSION NUMBER**: 0001104659-25-083112

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 15

**FILED AS OF DATE**: 20250826

**DATE AS OF CHANGE**: 20250826

**EFFECTIVENESS DATE**: 20250826

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MAXCYTE, INC.
- **CENTRAL INDEX KEY:** 0001287098
- **STANDARD INDUSTRIAL CLASSIFICATION:** SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 522210438
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-289865
- **FILM NUMBER:** 251258082

**BUSINESS ADDRESS:**
- **STREET 1:** 9713 KEY WEST AVENUE,
- **STREET 2:** SUITE 400
- **CITY:** ROCKVILLE
- **STATE:** MD
- **ZIP:** 20850
- **BUSINESS PHONE:** 301-517-5556

**MAIL ADDRESS:**
- **STREET 1:** 9713 KEY WEST AVENUE,
- **STREET 2:** SUITE 400
- **CITY:** ROCKVILLE
- **STATE:** MD
- **ZIP:** 20850

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MAXCYTE INC
- **DATE OF NAME CHANGE:** 20040415

**As filed with the Securities and Exchange Commission on August 26, 2025**

**Registration No. 333-** 

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

------

**Form S-8**

**REGISTRATION STATEMENT**

***UNDER***

***THE SECURITIES ACT OF 1933***

------

**MaxCyte, Inc.**

**(Exact name of registrant as specified in its charter)**

------

---

| | |
|:---|:---|
| **Delaware** | **52-2210438** |
| (State or other jurisdiction of | (IRS employer |
| incorporation or organization) | identification number) |
| **9713 Key West Avenue, Suite 400** |  |
| **Rockville, Maryland** | **20850** |
| (Address of Principal Executive Offices) | (Zip Code) |

---

------

**MaxCyte, Inc. 2022 Equity Incentive Plan**

**MaxCyte, Inc. 2021 Employee Stock Purchase Plan**

(Full titles of the plans)

**Maher Masoud**

**President and Chief Executive Officer**

**MaxCyte, Inc.**

**9713 Key West Avenue, Suite 400**

**Rockville, Maryland 20850**

**(301) 944-1700**

(Name, address, including zip code and telephone number, including area code, of agent for service)

***Copies to:***

---

| | |
|:---|:---|
| **David Sandoval** | **Asher Rubin** |
| **Senior VP and General Counsel** | **Sidley Austin LLP** |
| **MaxCyte, Inc.** | **2850 Quarry Lake Drive, Suite 301** |
| **9713 Key West Avenue, Suite 400** | **Baltimore, Maryland 21209** |
| **Rockville, Maryland 20850** | **(410) 559-2881** |
| **(301) 944-1700** |  |

---

------

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

---

| | | | |
|:---|:---|:---|:---|
| Large accelerated filer | ◻ | Smaller reporting company | ⌧ |
| Non-accelerated filer | ⌧ | Accelerated filer | ¨ |
|  |  | Emerging growth company | ⌧ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ¨

**EXPLANATORY NOTE**

This Registration Statement on Form S-8 is being filed for the purpose of registering: (i) an additional 11,319,000 shares of common stock, par value $0.01 per share (the "***Common Stock***"), of MaxCyte, Inc., a Delaware corporation (the "***Registrant***"), to be issued pursuant to the MaxCyte, Inc. 2022 Equity Incentive Plan, as amended (the "***2022 EIP***"), which shares of Common Stock are in addition to the shares of Common Stock registered on the Registrant's Registration Statement on Form S-8 filed with the Securities and Exchange Commission (the "***Commission***") on [July 14, 2022 (File No. 333-266133)](https://www.sec.gov/Archives/edgar/data/1287098/000110465922079885/tm2220850d1_s8.htm) and (ii) an additional 3,120,706 shares of Common Stock to be issued pursuant to the MaxCyte, Inc. 2021 Employee Stock Purchase Plan (the "***2021 ESPP***," and the 2022 EIP and the 2021 ESPP, together, the "***Plans***"), which shares of Common Stock are in addition to the shares of Common Stock registered on the Registrant's Registration Statement on Form S-8 filed with the Commission on [July 14, 2022 (File No. 333-266133)](https://www.sec.gov/Archives/edgar/data/1287098/000110465922079885/tm2220850d1_s8.htm). The Registrant's prior Registration Statement on Form S-8, which is referenced in the preceding sentence is referred to as the "***Prior Registration Statement*** ."

The Prior Registration Statement is currently effective. This Registration Statement relates to securities of the same class as those to which the Prior Registration Statement relates and is submitted in accordance with General Instruction E of Form S-8 regarding Registration of Additional Securities. Pursuant to General Instruction E of Form S-8, the contents of the Prior Registration Statement are incorporated herein by reference and made part of this Registration Statement, except for Items 3 and 8, which are being updated by this Registration Statement.

**PART I**

**INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS**

**Item 1.** **Plan Information.**

The documents containing the information specified in Part I will be delivered in accordance with Rule 428(b) under the Securities Act of 1933, as amended (the "***Securities Act***"). Such documents are not required to be, and are not, filed with the Commission, either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities Act. These documents, and the documents incorporated by reference under this Registration Statement pursuant to Item 3 of Part II of the Form S-8, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.

**Item 2.** **Registrant Information and Employee Plan Annual Information.**

The written statement required by Item 2 of Part I is included in documents that will be delivered to participants in the Plans pursuant to Rule 428(b) of the Securities Act.

**PART II**

**INFORMATION REQUIRED IN THE REGISTRATION STATEMENT**

**Item 3.** **Incorporation of Documents by Reference.**

The following documents filed by the Registrant with the Commission are incorporated by reference into this Registration Statement:

1. The Registrant's [Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the Commission on March 11, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1287098/000155837025002721/mxct-20241231x10k.htm) ;

2. The Registrant's Quarterly Reports on Form 10-Q for the quarterly periods ended [March 31, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1287098/000155837025007005/mxct-20250331x10q.htm) and [June 30, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1287098/000155837025010554/mxct-20250630x10q.htm) ;

3. The Registrant's Current Reports on
 Form 8-K (except for the information furnished under Items 2.02 and 7.01 therein), filed with the Commission on [June 18, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1287098/000155837025008730/mxct-20250618x8k.htm) , [June 25, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1287098/000155837025008856/mxct-20250625x8k.htm) and [August 11, 2025](https://www.sec.gov/ix?doc=/Archives/edgar/data/1287098/000155837025011056/mxct-20250811x8k.htm) ;

4. The description of the Common Stock contained in the Registrant's Registration Statement on [Form 8-A (File No. 001-40674), filed with the Commission on July 27, 2021](https://www.sec.gov/Archives/edgar/data/1287098/000110465921095955/tm2113965d10_8a12b.htm) , under Section 12(b) of the Securities Exchange Act of 1934, as amended (the "  ***Exchange Act*** "), including any amendments or reports filed for the purpose of updating such description, including [Exhibit 4.1](https://www.sec.gov/Archives/edgar/data/1287098/000155837022004081/mxct-20211231xex4d1.htm) to the Registrant's Annual Report on Form 10-K for the fiscal year ended December 31, 2022, filed with the Commission on March 22, 2022; and

5. All documents, reports and definitive proxy or information statements filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act (other than Current Reports furnished under Item 2.02 or Item 7.01 of Form 8-K and exhibits furnished on such form that relate to such items) on or after the date of this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement that indicates that all securities offered have been sold or that deregisters all securities then remaining unsold shall be deemed to be incorporated by reference in this Registration Statement and to be part hereof from the date of filing of such documents. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any subsequently filed document that also is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.

**Item 8.** **Exhibits.**

The exhibits to this Registration Statement are listed below:

---

| | |
|:---|:---|
| **Exhibit<br> Number** | **Exhibit Description** |
| [4.1](https://www.sec.gov/Archives/edgar/data/1287098/000110465921095556/tm2113965d9_ex3-1.htm) | [Fifteenth Amended and Restated Certificate of Incorporation (incorporated herein by reference to Exhibit 3.1 to the Registrant's Registration Statement on Form S-1 (File No. 333-257810), filed with the Commission on July 26, 2021).](https://www.sec.gov/Archives/edgar/data/1287098/000110465921095556/tm2113965d9_ex3-1.htm) |
| [4.2](https://www.sec.gov/Archives/edgar/data/1287098/000110465921100067/tm2113965d16_ex3-1.htm) | [Amended and Restated Bylaws (incorporated herein by reference to Exhibit 3.1 to the Registrant's Current Report on Form 8-K (File No. 001-40674), filed with the Commission on August 4, 2021).](https://www.sec.gov/Archives/edgar/data/1287098/000110465921100067/tm2113965d16_ex3-1.htm) |
| [<u>5.1\*</u>](tm2524224d1_ex5-1.htm) | [Opinion of Sidley Austin LLP](tm2524224d1_ex5-1.htm) |
| [<u>23.1\*</u>](tm2524224d1_ex23-1.htm) | [<u>Consent of Independent Registered Public Accounting Firm.</u>](tm2524224d1_ex23-1.htm) |
| [<u>23.2\*</u>](tm2524224d1_ex5-1.htm) | [<u>Consent of Sidley Austin LLP (included in Exhibit 5.1).</u>](tm2524224d1_ex5-1.htm) |
| [24.1<u>\*</u>](#a_001) | [Power of Attorney (included on the signature page of this Registration Statement).](#a_001) |
| [99.1](https://www.sec.gov/Archives/edgar/data/1287098/000155837025008730/mxct-20250618xex10d1.htm) | [MaxCyte, Inc. 2022 Equity Incentive Plan (incorporated herein by reference to Exhibit 10.1 to the Registrant's Current Report on Form 8-K (File No. 001-40674), filed with the Commission on June 18, 2025).](https://www.sec.gov/Archives/edgar/data/1287098/000155837025008730/mxct-20250618xex10d1.htm) |
| [99.2](https://www.sec.gov/Archives/edgar/data/1287098/000110465922079885/tm2220850d1_ex99-2.htm) | [MaxCyte, Inc. 2021 Employee Stock Purchase Plan (incorporated herein by reference to Exhibit 99.2 to the Registrant's Registration Statement on Form S-8 (File No. 333-266133), filed with the Commission on June 14, 2022).](https://www.sec.gov/Archives/edgar/data/1287098/000110465922079885/tm2220850d1_ex99-2.htm) |
| [<u>107\*</u>](tm2524224d1_ex-filingfees.htm) | [<u>Filing Fee Table.</u>](tm2524224d1_ex-filingfees.htm) |
| \* | Filed herewith. |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Rockville, Maryland, on August 26, 2025.

---

| | |
|:---|:---|
| **MaxCyte, Inc.** | **MaxCyte, Inc.** |
| By: | /s/ Maher Masoud |
| Name: | Maher Masoud |
| Title: | President and Chief Executive Officer |

---

**POWER OF ATTORNEY**

**KNOW ALL PERSONS BY THESE PRESENTS,** that each person whose signature appears below constitutes and appoints Maher Masoud, Douglas Swirsky and David Sandoval and each or any one of them, his or her true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this registration statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their or his or her substitutes or substitute, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement on Form S-8 has been signed by the following persons in the capacities and on the dates indicated.

---

| | | |
|:---|:---|:---|
| **Signature** | **Title** | **Date** |
| /s/ Maher Masoud | President, Chief Executive Officer and Director |  |
| Maher Masoud | (Principal Executive Officer) | August 26, 2025 |
| /s/ Douglas Swirsky | Chief Financial Officer |  |
| Douglas Swirsky | (Principal Financial Officer and Principal Accounting Officer) | August 26, 2025 |
| /s/ Richard Douglas |  |  |
| Richard Douglas, PhD | Chairman of the Board | August 26, 2025 |
| /s/ Yasir Al-Wakeel |  |  |
| Yasir Al-Wakeel, BM BCh | Director | August 26, 2025 |
| /s/ Patrick Balthrop |  |  |
| Patrick Balthrop, Sr. | Director | August 26, 2025 |
| /s/ Will Brooke |  |  |
| Will Brooke | Director | August 26, 2025 |
| /s/ Cynthia Collins |  |  |
| Cynthia Collins | Director | August 26, 2025 |
| /s/ Stanley C. Erck |  |  |
| Stanley C. Erck | Director | August 26, 2025 |
| /s/ Rekha Hemrajani |  |  |
| Rekha Hemrajani | Director | August 26, 2025 |
| /s/ John Johnston |  |  |
| John Johnston | Director | August 26, 2025 |

---

## Exhibit 5.1

**Exhibit 5.1**

---

| | |
|:---|:---|
| ![](tm2524224d1_ex5-1img001.jpg) | Sidley Austin LLP<br> one south dearborn street<br> chicago, il 60603<br> +1 312 853 7000<br> +1 312 853 7036 FAX<br>AMERICA • ASIA PACIFIC • EUROPE |

---

August 26, 2025

MaxCyte, Inc.

9713 Key West Avenue, Suite 400

Rockville, Maryland 20850

---

| | |
|:---|:---|
| Re: | <u>14,439,706 shares of Common Stock, $0.01 par value per share</u> |

---

Ladies and Gentlemen:

We refer to the Registration Statement on Form S-8 (the "<u>Registration Statement</u>") being filed by MaxCyte, Inc., a Delaware corporation (the "<u>Company</u>"), with the Securities and Exchange Commission under the Securities Act of 1933, as amended (the "<u>Securities Act</u>"), relating to the registration of (i) 11,319,000 shares of common stock, $0.01 par value per share, of the Company (the "<u>Common Stock</u>"), which may be issued under the MaxCyte, Inc. 2022 Equity Incentive Plan, as amended (the "<u>2022 EIP</u>"), and (ii) 3,120,706 shares of Common Stock which may be issued under the MaxCyte, Inc. 2021 Employee Stock Purchase Plan (together with the 2022 EIP, the "<u>Plans</u>," and the aggregate number of shares of Common Stock to be registered under the Registration Statement, the "<u>Registered Shares</u>").

This opinion letter is being delivered in accordance with the requirements of Item 601(b)(5) of Regulation S-K under the Securities Act.

We have examined the Registration Statement, the Company's amended and restated certificate of incorporation and bylaws, the Plans, the resolutions adopted by the board of directors of the Company relating to the Registration Statement and the Plans, and the resolutions and proposals adopted by the stockholders of the Company relating to the Plans. We have also examined originals, or copies of originals certified to our satisfaction, of such agreements, documents, certificates and statements of the Company and other corporate documents and instruments, and have examined such questions of law, as we have considered relevant and necessary as a basis for this opinion letter. We have assumed the authenticity of all documents submitted to us as originals, the genuineness of all signatures, the legal capacity of all persons and the conformity with the original documents of any copies thereof submitted to us for examination. As to facts relevant to the opinions expressed herein, we have relied without independent investigation or verification upon, and assumed the accuracy and completeness of, certificates, letters and oral and written statements and representations of public officials and officers and other representatives of the Company.

Based on the foregoing, we are of the opinion that each Registered Share that is newly issued pursuant to each Plan will be validly issued, fully paid and non-assessable when: (i) the Registration Statement, as finally amended, shall have become effective under the Securities Act; (ii) such Registered Share shall have been duly issued and delivered in accordance with the applicable Plan; and (iii) a certificate representing such Registered Share shall have been duly executed, countersigned and registered and duly delivered to the person entitled thereto against payment of the agreed consideration therefor (in an amount not less than the par value thereof) or, if any such Registered Share is to be issued in uncertificated form, the Company's books shall reflect the issuance of such Registered Share to the person entitled thereto against payment of the agreed consideration therefor (in an amount not less than the par value thereof), all in accordance with the applicable Plan.

Sidley Austin LLP is a limited liability partnership practicing in affiliation with other Sidley Austin partnerships.

![](tm2524224d1_ex5-1img001.jpg)

MaxCyte, Inc.

August 26, 2025

This opinion letter is limited to the General Corporation Law of the State of Delaware. We express no opinion as to the laws, rules or regulations of any other jurisdiction, including, without limitation, the federal laws of the United States of America or any state securities or blue sky laws.

We hereby consent to the filing of this opinion letter as an exhibit to the Registration Statement and to all references to our Firm included in or made a part of the Registration Statement. In giving such consent, we do not thereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act.

---

| |
|:---|
| Very truly yours, |
| <u>/s/ Sidley Austin LLP</u> |
| Sidley Austin LLP |

---

## Exhibit 23.1

**Exhibit 23.1**

**Consent of Independent Registered Public Accounting Firm**

We consent to the incorporation by reference in the Registration Statement pertaining to MaxCyte, Inc. 2021 Employee Stock Purchase Plan and 2022 Equity Incentive Plan of our report dated March 11, 2025, with respect to the consolidated financial statements of MaxCyte Inc. included in the Annual Report (Form 10-K) for the year ended December 31, 2024.

/s/ CohnReznick LLP

Tysons, Virginia

August 26, 2025

## Ex-Filing

?xml version='1.0' encoding='ASCII'? EX-FILING FEES

---

| |
|:---|
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Calculation of Filing Fee Tables**  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **S-8**  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **MAXCYTE, INC.**  |

---

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| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Security Type**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Security Class Title**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Fee Calculation Rule**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Amount Registered**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Proposed Maximum Offering Price Per Unit**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Maximum Aggregate Offering Price**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Fee Rate**  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Amount of Registration Fee**  |
| 1 | Equity | Common Stock, $0.01 par value per share | Other | 11319000 | $1.40 | $15846600.00 | 0.0001531 | $2426.11 |
| 2 | Equity | Common Stock, $.01 par value per share | Other | 3120706 | $1.40 | $4368988.40 | 0.0001531 | $668.89 |
| Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: | Total Offering Amounts: |  | $20215588.40  |  | $3095.00  |
| Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  | Total Fee Offsets:  |  |  |  | $0.00  |
| Net Fee Due:  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  | Net Fee Due:  |  |  |  | $3095.00  |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Offering Note** <br>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <sup>1</sup> (a) Represents shares of the Registrant's Common Stock that were added to the MaxCyte, Inc. 2022 Equity Incentive Plan (the "2022 EIP"), pursuant to share reserve increases approved by the Registrant's Board of Directors and stockholders in each of 2023, 2024 and 2025. Pursuant to Rule 416(a) promulgated under the Securities Act of 1933, as amended, or the Securities Act, this Registration Statement shall also cover any additional shares of Registrant's Common Stock that become issuable under the 2022 EIP by reason of any stock dividend, stock split, recapitalization, or other similar transaction effected that results in an increase to the number of outstanding shares of Registrant's Common Stock, as applicable. (b) Estimated in accordance with Rules 457(c) and 457(h) solely for the purpose of calculating the registration fee on the basis of $1.40 per share, the average of the high and low prices of the Registrant's Common Stock on August 21, 2025 as reported on the Nasdaq Global Select Market.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <sup>2</sup> (a) Represents shares of the Registrant's Common Stock that were automatically added to the shares authorized for issuance under the MaxCyte, Inc. 2021 Employee Stock Purchase Plan (the "2021 ESPP") on January 1st of each year for a period of up to ten years, commencing on January 1, 2022 and ending on (and including) January 1, 2031, in an amount equal to the lesser of (i) 1% of the total number of shares of Common Stock outstanding on December 31st of the preceding calendar year, and (ii) 3,006,435 shares of Common Stock. Pursuant to Rule 416(a) promulgated under the Securities Act of 1933, as amended, or the Securities Act, this Registration Statement shall also cover any additional shares of Registrant's Common Stock that become issuable under the 2021 ESPP by reason of any stock dividend, stock split, recapitalization, or other similar transaction effected that results in an increase to the number of outstanding shares of Registrant's Common Stock, as applicable. (b) Estimated in accordance with Rules 457(c) and 457(h) solely for the purpose of calculating the registration fee on the basis of $1.40 per share, the average of the high and low prices of the Registrant's Common Stock on August 21, 2025 as reported on the Nasdaq Global Select Market.

---

| | |
|:---|:---|
| | |
| **Rule 457(p)** | **Rule 457(p)** |
| Fee Offset Claims | N/A |
| Fee Offset Sources | N/A |

---