# EDGAR Filing Document

**Accession Number:** 0001276144
**File Stem:** 0001999371-26-003461
**Filing Date:** 2026-2
**Character Count:** 14667
**Document Hash:** 4d19495654790f3c4d0853d262fc2107
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001999371-26-003461.hdr.sgml**: 20260217

**ACCESSION NUMBER**: 0001999371-26-003461

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260217

**DATE AS OF CHANGE**: 20260217

**EFFECTIVENESS DATE**: 20260217

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** CLOUGH CAPITAL PARTNERS L P
- **CENTRAL INDEX KEY:** 0001276144

**ORGANIZATION NAME:**
- **EIN:** 043486480
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-10679
- **FILM NUMBER:** 26640004

**BUSINESS ADDRESS:**
- **STREET 1:** 53 STATE STREET
- **STREET 2:** 27TH FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02109
- **BUSINESS PHONE:** 6172043400

**MAIL ADDRESS:**
- **STREET 1:** 53 STATE STREET
- **STREET 2:** 27TH FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02109

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 12-31-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** CLOUGH CAPITAL PARTNERS L P<br>**Address:** 53 State Street<br>27th Floor<br>Boston, MA 02109

**Form 13F File Number:** 028-10679

**CRD Number (if applicable):** 000131257

**SEC File Number (if applicable):** 801-63142

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Daniel Gillis<br>**Title:** Chief Compliance Officer<br>**Phone:** 617-204-3409

**Signature, Place, and Date of Signing:**

/s/ Daniel Gillis  Boston, MA  02-17-2026<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 1

**Form 13F Information Table Entry Total:** 108

**Form 13F Information Table Value Total:** $1126161402

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

| No.   | Name              | Form 13F File Number   |
|:---|:---|:---|
|  | Clough Charles JR | 028-12502              |

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 10X GENOMICS INC | CL A COM | 88025U109 |  | 9955200 | 610374 | SH |  | DFND | 1 | 610374 | 0 | 0 |
| AERCAP HOLDINGS NV | SHS | N00985106 |  | 4210155 | 29286 | SH |  | DFND | 1 | 29286 | 0 | 0 |
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 |  | 21592700 | 147310 | SH |  | DFND | 1 | 147310 | 0 | 0 |
| ALPHABET INC | CAP STK CL C | 02079K107 |  | 54387188 | 173318 | SH |  | DFND | 1 | 173318 | 0 | 0 |
| AMAZON COM INC | COM | 023135106 |  | 56965453 | 246796 | SH |  | DFND | 1 | 246796 | 0 | 0 |
| AMPHENOL CORP NEW | CL A | 032095101 |  | 18566749 | 137389 | SH |  | DFND | 1 | 137389 | 0 | 0 |
| ANTERO RESOURCES CORP | COM | 03674X106 |  | 11848072 | 343821 | SH |  | DFND | 1 | 343821 | 0 | 0 |
| APPLE INC | COM | 037833100 |  | 30978991 | 113952 | SH |  | DFND | 1 | 113952 | 0 | 0 |
| ARCELLX INC | COMMON STOCK | 03940C100 |  | 8461656 | 129780 | SH |  | DFND | 1 | 129780 | 0 | 0 |
| ARCOS DORADOS HOLDINGS INC | SHS CLASS -A - | G0457F107 |  | 1081138 | 147294 | SH |  | DFND | 1 | 147294 | 0 | 0 |
| ASML HOLDING N V | N Y REGISTRY SHS | N07059210 |  | 2089437 | 1953 | SH |  | DFND | 1 | 1953 | 0 | 0 |
| BANK AMERICA CORP | COM | 060505104 |  | 1320000 | 24000 | SH |  | DFND | 1 | 24000 | 0 | 0 |
| BOEING CO | COM | 097023105 |  | 37921094 | 174655 | SH |  | DFND | 1 | 174655 | 0 | 0 |
| BOEING CO | COM | 097023105 |  | 9119040 | 42000 | SH | Call | DFND | 1 | 42000 | 0 | 0 |
| BOOKING HOLDINGS INC | COM | 09857L108 |  | 4948325 | 924 | SH |  | DFND | 1 | 924 | 0 | 0 |
| BOOZ ALLEN HAMILTON HLDG COR | CL A | 099502106 |  | 19283009 | 228580 | SH |  | DFND | 1 | 228580 | 0 | 0 |
| BOSTON SCIENTIFIC CORP | COM | 101137107 |  | 13200254 | 138440 | SH |  | DFND | 1 | 138440 | 0 | 0 |
| BROADCOM INC | COM | 11135F101 |  | 35016668 | 101175 | SH |  | DFND | 1 | 101175 | 0 | 0 |
| BROOKDALE SR LIVING INC | COM | 112463104 |  | 5743517 | 532300 | SH |  | DFND | 1 | 532300 | 0 | 0 |
| BUTTERFLY NETWORK INC | COM CL A | 124155102 |  | 845462 | 222490 | SH |  | DFND | 1 | 222490 | 0 | 0 |
| BWX TECHNOLOGIES INC | COM | 05605H100 |  | 17216592 | 99610 | SH |  | DFND | 1 | 99610 | 0 | 0 |
| CARNIVAL CORP | UNIT 99/99/9999 | 143658300 |  | 40220966 | 1316993 | SH |  | DFND | 1 | 1316993 | 0 | 0 |
| CARNIVAL CORP | UNIT 99/99/9999 | 143658300 |  | 4865022 | 159300 | SH | Call | DFND | 1 | 159300 | 0 | 0 |
| CHENIERE ENERGY INC | COM NEW | 16411R208 |  | 9789480 | 50360 | SH |  | DFND | 1 | 50360 | 0 | 0 |
| CITIGROUP INC | COM NEW | 172967424 |  | 8577882 | 73510 | SH |  | DFND | 1 | 73510 | 0 | 0 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 |  | 1206120 | 23000 | SH |  | DFND | 1 | 23000 | 0 | 0 |
| D R HORTON INC | COM | 23331A109 |  | 33311402 | 231281 | SH |  | DFND | 1 | 231281 | 0 | 0 |
| DELL TECHNOLOGIES INC | CL C | 24703L202 |  | 15046688 | 119532 | SH |  | DFND | 1 | 119532 | 0 | 0 |
| DENALI THERAPEUTICS INC | COM | 24823R105 |  | 855713 | 51830 | SH |  | DFND | 1 | 51830 | 0 | 0 |
| DUKE ENERGY CORP NEW | COM NEW | 26441C204 |  | 6253388 | 53352 | SH |  | DFND | 1 | 53352 | 0 | 0 |
| EATON CORP PLC | SHS | G29183103 |  | 12877359 | 40430 | SH |  | DFND | 1 | 40430 | 0 | 0 |
| ENCOMPASS HEALTH CORP | COM | 29261A100 |  | 10136476 | 95501 | SH |  | DFND | 1 | 95501 | 0 | 0 |
| EVEREST GROUP LTD | COM | G3223R108 |  | 9455988 | 27865 | SH |  | DFND | 1 | 27865 | 0 | 0 |
| EXPAND ENERGY CORPORATION | COM | 165167735 |  | 24799547 | 224715 | SH |  | DFND | 1 | 224715 | 0 | 0 |
| EXXON MOBIL CORP | COM | 30231G102 |  | 879685 | 7310 | SH |  | DFND | 1 | 7310 | 0 | 0 |
| FIDELIS INSURANCE HOLDINGS L | COM | G3398L118 |  | 11880047 | 607054 | SH |  | DFND | 1 | 607054 | 0 | 0 |
| GE AEROSPACE | COM NEW | 369604301 |  | 15841983 | 51430 | SH |  | DFND | 1 | 51430 | 0 | 0 |
| GENEDX HOLDINGS CORP | COM CL A | 81663L200 |  | 1793397 | 13789 | SH |  | DFND | 1 | 13789 | 0 | 0 |
| GENERAL DYNAMICS CORP | COM | 369550108 |  | 17523153 | 52050 | SH |  | DFND | 1 | 52050 | 0 | 0 |
| GILEAD SCIENCES INC | COM | 375558103 |  | 773262 | 6300 | SH |  | DFND | 1 | 6300 | 0 | 0 |
| GLAUKOS CORP | COM | 377322102 |  | 2299751 | 20368 | SH |  | DFND | 1 | 20368 | 0 | 0 |
| HDFC BANK LTD | SPONSORED ADS | 40415F101 |  | 1568662 | 42930 | SH |  | DFND | 1 | 42930 | 0 | 0 |
| HELMERICH  PAYNE INC | COM | 423452101 |  | 2229641 | 77742 | SH |  | DFND | 1 | 77742 | 0 | 0 |
| HUNTINGTON INGALLS INDS INC | COM | 446413106 |  | 22764286 | 66940 | SH |  | DFND | 1 | 66940 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 |  | 2127890 | 12517 | SH |  | DFND | 1 | 12517 | 0 | 0 |
| JOHNSON  JOHNSON | COM | 478160104 |  | 642994 | 3107 | SH |  | DFND | 1 | 3107 | 0 | 0 |
| JPMORGAN CHASE  CO. | COM | 46625H100 |  | 16758662 | 52010 | SH |  | DFND | 1 | 52010 | 0 | 0 |
| KINROSS GOLD CORP | COM | 496902404 |  | 2043853 | 72580 | SH |  | DFND | 1 | 72580 | 0 | 0 |
| KRATOS DEFENSE  SEC SOLUTIO | COM NEW | 50077B207 |  | 1658937 | 21854 | SH |  | DFND | 1 | 21854 | 0 | 0 |
| KRYSTAL BIOTECH INC | COM | 501147102 |  | 1924491 | 7806 | SH |  | DFND | 1 | 7806 | 0 | 0 |
| KYMERA THERAPEUTICS INC | COM | 501575104 |  | 850074 | 10925 | SH |  | DFND | 1 | 10925 | 0 | 0 |
| LAS VEGAS SANDS CORP | COM | 517834107 |  | 23562710 | 362002 | SH |  | DFND | 1 | 362002 | 0 | 0 |
| LIBERTY MEDIA CORP DEL | COM LBTY ONE S C | 531229755 |  | 3563501 | 36174 | SH |  | DFND | 1 | 36174 | 0 | 0 |
| LOCKHEED MARTIN CORP | COM | 539830109 |  | 1245450 | 2575 | SH |  | DFND | 1 | 2575 | 0 | 0 |
| LUMENTUM HLDGS INC | COM | 55024U109 |  | 922949 | 2504 | SH |  | DFND | 1 | 2504 | 0 | 0 |
| MAKEMYTRIP LIMITED MAURITIUS | SHS | V5633W109 |  | 851913 | 10374 | SH |  | DFND | 1 | 10374 | 0 | 0 |
| MELCO RESORTS AND ENTMNT LTD | ADR | 585464100 |  | 8485364 | 1120920 | SH |  | DFND | 1 | 1120920 | 0 | 0 |
| MERCADOLIBRE INC | COM | 58733R102 |  | 9747004 | 4839 | SH |  | DFND | 1 | 4839 | 0 | 0 |
| META PLATFORMS INC | CL A | 30303M102 |  | 38320205 | 58053 | SH |  | DFND | 1 | 58053 | 0 | 0 |
| MICRON TECHNOLOGY INC | COM | 595112103 |  | 9224451 | 32320 | SH |  | DFND | 1 | 32320 | 0 | 0 |
| MICROSOFT CORP | COM | 594918104 |  | 20453257 | 42292 | SH |  | DFND | 1 | 42292 | 0 | 0 |
| MORGAN STANLEY | COM NEW | 617446448 |  | 1762518 | 9928 | SH |  | DFND | 1 | 9928 | 0 | 0 |
| MOSAIC CO NEW | COM | 61945C103 |  | 997085 | 41390 | SH |  | DFND | 1 | 41390 | 0 | 0 |
| NEWMONT CORP | COM | 651639106 |  | 2050120 | 20532 | SH |  | DFND | 1 | 20532 | 0 | 0 |
| NORTHROP GRUMMAN CORP | COM | 666807102 |  | 8733336 | 15316 | SH |  | DFND | 1 | 15316 | 0 | 0 |
| NU HLDGS LTD | ORD SHS CL A | G6683N103 |  | 1947481 | 116337 | SH |  | DFND | 1 | 116337 | 0 | 0 |
| NVENT ELECTRIC PLC | SHS | G6700G107 |  | 1031529 | 10116 | SH |  | DFND | 1 | 10116 | 0 | 0 |
| NVIDIA CORPORATION | COM | 67066G104 |  | 37697245 | 202130 | SH |  | DFND | 1 | 202130 | 0 | 0 |
| PALO ALTO NETWORKS INC | COM | 697435105 |  | 7235192 | 39279 | SH |  | DFND | 1 | 39279 | 0 | 0 |
| PAN AMERN SILVER CORP | COM | 697900108 |  | 2153379 | 41563 | SH |  | DFND | 1 | 41563 | 0 | 0 |
| PDD HOLDINGS INC | SPONSORED ADS | 722304102 |  | 958146 | 8450 | SH |  | DFND | 1 | 8450 | 0 | 0 |
| PENNYMAC FINL SVCS INC NEW | COM | 70932M107 |  | 5390938 | 40890 | SH |  | DFND | 1 | 40890 | 0 | 0 |
| PLANET LABS PBC | COM CL A | 72703X106 |  | 976377 | 49512 | SH |  | DFND | 1 | 49512 | 0 | 0 |
| PULTE GROUP INC | COM | 745867101 |  | 33399635 | 284834 | SH |  | DFND | 1 | 284834 | 0 | 0 |
| PURECYCLE TECHNOLOGIES INC | COM | 74623V103 |  | 884547 | 102974 | SH |  | DFND | 1 | 102974 | 0 | 0 |
| QUANTA SVCS INC | COM | 74762E102 |  | 1903069 | 4509 | SH |  | DFND | 1 | 4509 | 0 | 0 |
| REDDIT INC | CL A | 75734B100 |  | 3807337 | 16563 | SH |  | DFND | 1 | 16563 | 0 | 0 |
| RH | COM | 74967X103 |  | 2265889 | 12648 | SH |  | DFND | 1 | 12648 | 0 | 0 |
| ROCKET COS INC | COM CL A | 77311W101 |  | 33271709 | 1718580 | SH |  | DFND | 1 | 1718580 | 0 | 0 |
| ROLLINS INC | COM | 775711104 |  | 1402547 | 23368 | SH |  | DFND | 1 | 23368 | 0 | 0 |
| ROYAL CARIBBEAN GROUP | COM | V7780T103 |  | 31919884 | 114441 | SH |  | DFND | 1 | 114441 | 0 | 0 |
| RTX CORPORATION | COM | 75513E101 |  | 25346980 | 138206 | SH |  | DFND | 1 | 138206 | 0 | 0 |
| SABLE OFFSHORE CORP | COM SHS | 78574H104 |  | 1558927 | 172830 | SH |  | DFND | 1 | 172830 | 0 | 0 |
| SCHWAB CHARLES CORP | COM | 808513105 |  | 32524502 | 325538 | SH |  | DFND | 1 | 325538 | 0 | 0 |
| SELECT MED HLDGS CORP | COM | 81619Q105 |  | 2569199 | 173010 | SH |  | DFND | 1 | 173010 | 0 | 0 |
| SELECT WATER SOLUTIONS INC | CL A COM | 81617J301 |  | 1028014 | 97720 | SH |  | DFND | 1 | 97720 | 0 | 0 |
| SERVICE CORP INTL | COM | 817565104 |  | 2392587 | 30686 | SH |  | DFND | 1 | 30686 | 0 | 0 |
| SIMON PPTY GROUP INC NEW | COM | 828806109 |  | 888528 | 4800 | SH |  | DFND | 1 | 4800 | 0 | 0 |
| SITIME CORP | COM | 82982T106 |  | 1720388 | 4871 | SH |  | DFND | 1 | 4871 | 0 | 0 |
| SOLARIS ENERGY INFRAS INC | COM CL A | 83418M103 |  | 2249404 | 48932 | SH |  | DFND | 1 | 48932 | 0 | 0 |
| SPOTIFY TECHNOLOGY S A | SHS | L8681T102 |  | 2078361 | 3579 | SH |  | DFND | 1 | 3579 | 0 | 0 |
| STARBUCKS CORP | COM | 855244109 |  | 973804 | 11564 | SH |  | DFND | 1 | 11564 | 0 | 0 |
| TAIWAN SEMICONDUCTOR MFG LTD | SPONSORED ADS | 874039100 |  | 1148400 | 3779 | SH |  | DFND | 1 | 3779 | 0 | 0 |
| TE CONNECTIVITY PLC | ORD SHS | G87052109 |  | 6267901 | 27550 | SH |  | DFND | 1 | 27550 | 0 | 0 |
| TECHNIPFMC PLC | COM | G87110105 |  | 2325141 | 52180 | SH |  | DFND | 1 | 52180 | 0 | 0 |
| TELEDYNE TECHNOLOGIES INC | COM | 879360105 |  | 14680934 | 28745 | SH |  | DFND | 1 | 28745 | 0 | 0 |
| TESLA INC | COM | 88160R101 |  | 2570150 | 5715 | SH |  | DFND | 1 | 5715 | 0 | 0 |
| TEXTRON INC | COM | 883203101 |  | 16861293 | 193430 | SH |  | DFND | 1 | 193430 | 0 | 0 |
| TJX COS INC NEW | COM | 872540109 |  | 2643014 | 17206 | SH |  | DFND | 1 | 17206 | 0 | 0 |
| TRANSMEDICS GROUP INC | COM | 89377M109 |  | 866026 | 7119 | SH |  | DFND | 1 | 7119 | 0 | 0 |
| TRANSOCEAN LTD | REGISTERED SHS | H8817H100 |  | 18905566 | 4577619 | SH |  | DFND | 1 | 4577619 | 0 | 0 |
| UNITEDHEALTH GROUP INC | COM | 91324P102 |  | 5314771 | 16100 | SH |  | DFND | 1 | 16100 | 0 | 0 |
| UNIVERSAL HLTH SVCS INC | CL B | 913903100 |  | 16711233 | 76650 | SH |  | DFND | 1 | 76650 | 0 | 0 |
| VALE S A | SPONSORED ADS | 91912E105 |  | 2149012 | 164928 | SH |  | DFND | 1 | 164928 | 0 | 0 |
| VIKING HOLDINGS LTD | ORD SHS | G93A5A101 |  | 2103167 | 29452 | SH |  | DFND | 1 | 29452 | 0 | 0 |
| WALMART INC | COM | 931142103 |  | 1296478 | 11637 | SH |  | DFND | 1 | 11637 | 0 | 0 |
| WARBY PARKER INC | CL A COM | 93403J106 |  | 1565110 | 71827 | SH |  | DFND | 1 | 71827 | 0 | 0 |
| WYNN RESORTS LTD | COM | 983134107 |  | 15550246 | 129230 | SH |  | DFND | 1 | 129230 | 0 | 0 |

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