# EDGAR Filing Document

**Accession Number:** 0001100663
**File Stem:** 0001193125-25-202143
**Filing Date:** 2025-9
**Character Count:** 2905
**Document Hash:** aa014f55f8eda0e98e726e36211c2803
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-202143.hdr.sgml**: 20250912

**ACCESSION NUMBER**: 0001193125-25-202143

**CONFORMED SUBMISSION TYPE**: 497

**PUBLIC DOCUMENT COUNT**: 11

**FILED AS OF DATE**: 20250912

**DATE AS OF CHANGE**: 20250912

**EFFECTIVENESS DATE**: 20250912

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** iSHARES TRUST
- **CENTRAL INDEX KEY:** 0001100663

**ORGANIZATION NAME:**
- **EIN:** 943351276
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 497
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-92935
- **FILM NUMBER:** 251311314

**BUSINESS ADDRESS:**
- **STREET 1:** 400 HOWARD STREET
- **CITY:** SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94105
- **BUSINESS PHONE:** (415) 670-2000

**MAIL ADDRESS:**
- **STREET 1:** 400 HOWARD STREET
- **CITY:** SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94105

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ISHARES TRUST
- **DATE OF NAME CHANGE:** 19991213

## Series and Classes Contracts Data

### iShares Neuroscience and Healthcare ETF (Series ID: S000076483)

---

|  |  |  |
|:---|:---|:---|
| Class Name                              | Ticker Symbol | Class ID   |
| iShares Neuroscience and Healthcare ETF | IBRN          | C000236410 |

---

## Series and Classes Contracts Data

### iShares Neuroscience and Healthcare ETF (Series ID: S000076483)

| Class ID   | Class Name                              | Ticker Symbol   |
|:---|:---|:---|
| C000236410 | iShares Neuroscience and Healthcare ETF | IBRN            |

?xml version='1.0' encoding='ASCII'? Form 497

------

## iShares<sup>®</sup>

#### iShares Trust

#### Supplement dated September 12, 2025

#### to the currently effective Summary Prospectus, Prospectus and Statement of Additional Information (the "SAI")

#### for the iShares Neuroscience and Healthcare ETF (IBRN) (the "Fund")
**<u>Change in the Fund's "Summary of Principal Risks</u>"** 

The section of the Fund's Summary Prospectus and Prospectus entitled "Summary of Principal Risks" is amended to delete the paragraph entitled "Non-Diversification Risk".

**<u>Change in the Fund's "Additional Information About the Funds' Risks</u>"** 

In the table starting on page 6 of the Prospectus, the column for the Fund is amended to remove the checkmark (✓) in the row for "Non-Diversification Risk".

**Change in the Fund's "Investment Strategies and Risks"**

In the section of the Fund's SAI entitled, "Investment Strategies and Risks," the "Diversification Status" sub-section starting on page 3 is amended to move the Fund from the "Non-Diversified Funds" column to the "Diversified Funds" column.

If you have any questions, please call 1-800-iShares (1-800-474-2737).

iShares<sup>®</sup> is a registered trademark of BlackRock Fund Advisors and its affiliates.

IS-A-IBRN-0925

#### PLEASE RETAIN THIS SUPPLEMENT

#### FOR FUTURE REFERENCE