# EDGAR Filing Document

**Accession Number:** 0001847345
**File Stem:** 0001213900-26-015382
**Filing Date:** 2026-2
**Character Count:** 21322
**Document Hash:** 18c54d2e1ad120e3c0c47100437146fa
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-26-015382.hdr.sgml**: 20260212

**ACCESSION NUMBER**: 0001213900-26-015382

**CONFORMED SUBMISSION TYPE**: SCHEDULE 13G

**PUBLIC DOCUMENT COUNT**: 3

**FILED AS OF DATE**: 20260212

**DATE AS OF CHANGE**: 20260212

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Aspire Biopharma Holdings, Inc.
- **CENTRAL INDEX KEY:** 0001847345
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-93583
- **FILM NUMBER:** 26624954

**BUSINESS ADDRESS:**
- **STREET 1:** 23150 FASHION DRIVE, SUITE 232
- **CITY:** ESTERO
- **STATE:** FL
- **ZIP:** 33928
- **BUSINESS PHONE:** 561-704-8527

**MAIL ADDRESS:**
- **STREET 1:** 23150 FASHION DRIVE, SUITE 232
- **CITY:** ESTERO
- **STATE:** FL
- **ZIP:** 33928

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PowerUp Acquisition Corp.
- **DATE OF NAME CHANGE:** 20210222

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PowsedrUp Acquisition Corp.
- **DATE OF NAME CHANGE:** 20210222
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ARDSLEY ADVISORY PARTNERS LP
- **CENTRAL INDEX KEY:** 0000900529

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** NY
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SCHEDULE 13G

**BUSINESS ADDRESS:**
- **STREET 1:** 105 ROWAYTON AVE
- **CITY:** NORWALK
- **STATE:** CT
- **ZIP:** 06853
- **BUSINESS PHONE:** 203-564-4230

**MAIL ADDRESS:**
- **STREET 1:** 105 ROWAYTON AVE
- **CITY:** NORWALK
- **STATE:** CT
- **ZIP:** 06853

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ARDSLEY ADVISORY PARTNERS
- **DATE OF NAME CHANGE:** 19940208

## Exhibit 99.1

**Exhibit 1**

JOINT FILING AGREEMENT

In accordance with Rule 13d-1(f) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of this Schedule 13G (including amendments thereto) with respect to the Common Stock of Aspire Biopharma Holdings, Inc. and further agree that this Joint Filing Agreement be included as an Exhibit to such joint filing. In evidence thereof, the undersigned, hereby execute this Agreement this 12<sup>th</sup> day of February, 2026.

---

| |
|:---|
| February 12, 2026 |
| Date ARDSLEY ADVISORY PARTNERS LP |
| By: Ardsley Advisory Partners GP LLC, its general partner |
| /s/ Steve Napoli |
| Signature |
| Steve Napoli/ Member |
| Name/Title |
| February 12, 2026 |
| Date ARDSLEY ADVISORY PARTNERS GP LLC |
| /s/ Steve Napoli |
| Signature |
| Steve Napoli/ Member |
| Name/Title |
| February 12, 2026 |
| Date |
| ARDSLEY PARTNERS I GP LLC |
| /s/ Steve Napoli |
| Signature |
| Steve Napoli/ Member |
| Name/Title |
| February 12, 2026 |
| Date |
| PHILIP J. HEMPLEMAN |
| /s/ Steve Napoli\* |
| Signature |
| Steve Napoli/Attorney-in Fact for Philip J. Hempleman |
| Name/Title |
| February 12, 2026 |
| Date |
| ARDSLEY PARTNERS FUND II, L.P. |
| By: Ardsley Partners I GP LLC, its general partner |
| /s/ Steve Napoli |
| Signature |
| Steve Napoli/ Member |
| Name/Title |

---

---

| |
|:---|
| February 12, 2026 |
| Date |
| ARDSLEY PARTNERS ADVANCED HEALTHCARE FUND, L.P. |
| By: Ardsley Partners I GP LLC, its general partner |
| /s/ Steve Napoli |
| Signature |
| Steve Napoli/ Member |
| Name/Title |
| \* Executed by Steve Napoli as Attorney-in-Fact for Philip J. Hempleman. The Power of Attorney for Mr. Hempleman is attached as Exhibit 2 to the Statement on Schedule 13G with respect to the Common Stock of Vaxgen, Inc., filed on February 15, 2006, and is incorporated herein by reference. |

---

## Exhibit 99.2

**Exhibit 2**

IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

ARDSLEY ADVISORY PARTNERS LP

ARDSLEY ADVISORY PARTNERS GP LLC

ARDSLEY PARTNERS I GP LLC

PHILLIP J. HEMPLEMAN

ARDSLEY PARTNERS FUND II, L.P.<br> ARDSLEY PARTNERS ADVANCED HEALTHCARE FUND, L.P.

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## SCHEDULE 13G

### Under the Securities Exchange Act of 1934

**Issuer:** Aspire Biopharma Holdings, Inc.

**Title of Class of Securities:** Common Stock

**CUSIP Number:** 738920107

**Date of Event Which Requires Filing of this Statement:** 12/31/2025

**Check the appropriate box to designate the rule pursuant to which this Schedule is filed:**

- [x] Rule 13d-1(b)

- [x] Rule 13d-1(c)

- [ ] Rule 13d-1(d)

---

| 1. | Names of Reporting Persons<br>Ardsley Advisory Partners LP | Names of Reporting Persons<br>Ardsley Advisory Partners LP |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>10750000.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>10750000.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>7.76% | Percent of Class Represented by Amount in Row (9)<br>7.76% |
| 12. | Type of Reporting Person (See Instructions)<br>IA, PN | Type of Reporting Person (See Instructions)<br>IA, PN |

---

| 1. | Names of Reporting Persons<br>Ardsley Advisory Partners GP LLC | Names of Reporting Persons<br>Ardsley Advisory Partners GP LLC |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>10750000.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>10750000.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>7.76% | Percent of Class Represented by Amount in Row (9)<br>7.76% |
| 12. | Type of Reporting Person (See Instructions)<br>OO | Type of Reporting Person (See Instructions)<br>OO |

---

| 1. | Names of Reporting Persons<br>Ardsley Partners I GP LLC | Names of Reporting Persons<br>Ardsley Partners I GP LLC |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>10750000.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>10750000.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>7.76% | Percent of Class Represented by Amount in Row (9)<br>7.76% |
| 12. | Type of Reporting Person (See Instructions)<br>OO | Type of Reporting Person (See Instructions)<br>OO |

---

| 1. | Names of Reporting Persons<br>Ardsley Partners Advanced Healthcare Fund, L.P. | Names of Reporting Persons<br>Ardsley Partners Advanced Healthcare Fund, L.P. |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>9229100.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>9229100.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>9229100.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>9229100.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>6.67% | Percent of Class Represented by Amount in Row (9)<br>6.67% |
| 12. | Type of Reporting Person (See Instructions)<br>PN | Type of Reporting Person (See Instructions)<br>PN |

---

| 1. | Names of Reporting Persons<br>Ardsley Partners Fund II, L.P. | Names of Reporting Persons<br>Ardsley Partners Fund II, L.P. |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>DE | Citizenship or Place of Organization<br>DE |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>1520900.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>1520900.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1520900.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>1520900.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>1.10% | Percent of Class Represented by Amount in Row (9)<br>1.10% |
| 12. | Type of Reporting Person (See Instructions)<br>PN | Type of Reporting Person (See Instructions)<br>PN |

---

| 1. | Names of Reporting Persons<br>Philip J. Hempleman | Names of Reporting Persons<br>Philip J. Hempleman |
|:---|:---|:---|:---|
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] | Check the Appropriate Box if a Member of a Group (See Instructions)<br>(a) [x] (b) [ ] |
| 3. | SEC Use Only | SEC Use Only |
| 4. | Citizenship or Place of Organization<br>X1 | Citizenship or Place of Organization<br>X1 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 5. | Sole Voting Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 6. | Shared Voting Power<br>10750000.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 7. | Sole Dispositive Power<br>0.00 |
| Number of<br>Shares<br>Beneficially<br>Owned by<br>Each<br>Reporting<br>Person<br>With | 8. | Shared Dispositive Power<br>10750000.00 |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 | Aggregate Amount Beneficially Owned by Each Reporting Person<br>10750000.00 |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ] |
| 11. | Percent of Class Represented by Amount in Row (9)<br>7.76% | Percent of Class Represented by Amount in Row (9)<br>7.76% |
| 12. | Type of Reporting Person (See Instructions)<br>IN | Type of Reporting Person (See Instructions)<br>IN |

---

**Item 1(a). Name of Issuer:**
Aspire Biopharma Holdings, Inc.

**Item 1(b). Address of Issuer's Principal Executive Offices:**
23150 Fashion Drive, Suite 232, Estero, Florida 33928

**Item 2(a). Name of Person Filing:**
This Schedule 13G (the "Schedule") is being filed with respect to shares of Common Stock (as defined below) of Aspire Biopharma Holdings, Inc. (the "Issuer") which are beneficially owned by Ardsley Advisory Partners LP (the "Advisor"), Ardsley Advisory Partners GP LLC (the "Advisor General Partner"), Ardsley Partners I GP LLC (the "General Partner"), Ardsley Partners Advanced Healthcare Fund, L.P. (the "Advanced Healthcare Fund"), Ardsley Partners Fund II, L.P.  ("Fund II") and Phillip J. Hempleman ("Hempleman", and together with the Advisor, the Advisor General Partner, the General Partner, the Advanced Healthcare Fund and Fund II, collectively, the "Reporting Persons"). See Item 4 below.

**Item 2(b). Address of Principal Business Office:**
105 Rowayton Ave.
Norwalk, CT 06853

**Item 2(c). Citizenship:**
Each of the Advisor, the Advanced Healthcare Fund and Fund II is a Delaware limited partnership. Each of the Advisor General Partner and the General Partner is a Delaware limited liability company. Hempleman is a United States Citizen.

**Item 2(d). Title of Class of Securities:**
Common Stock

**Item 2(e). CUSIP Number:**
738920107

**Item 3. If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:**

(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d) [ ] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).

(e) [x] An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);

(f) [ ] An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);

(g) [ ] A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j) [ ] A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), if filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:

(k) [ ] Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).

**Item 4. Ownership:**

**(a) Amount beneficially owned:**

Ardsley Advisory Partners LP - 10,750,000
Ardsley Advisory Partners GP LLC - 10,750,000
Ardsley Partners I GP LLC - 10,750,000
Ardsley Partners Advanced Healthcare Fund, L.P. - 9,229,100
Ardsley Partners Fund II, L.P. - 1,520,900
Philip J. Hempleman - 10,750,000

**(b) Percent of class:**

Ardsley Advisory Partners LP - 7.76
Ardsley Advisory Partners GP LLC - 7.76
Ardsley Partners I GP LLC - 7.76
Ardsley Partners Advanced Healthcare Fund, L.P. - 6.67
Ardsley Partners Fund II, L.P. - 1.10
Philip J. Hempleman - 7.76

**(c) Number of shares as to which the person has:**

**(i) Sole power to vote or to direct the vote:**

Ardsley Advisory Partners LP - 0
Ardsley Advisory Partners GP LLC - 0
Ardsley Partners I GP LLC - 0
Ardsley Partners Advanced Healthcare Fund, L.P. - 0
Ardsley Partners Fund II, L.P. - 0
Philip J. Hempleman - 0

**(ii) Shared power to vote or to direct the vote:**

Ardsley Advisory Partners LP - 10,750,000
Ardsley Advisory Partners GP LLC - 10,750,000
Ardsley Partners I GP LLC - 10,750,000
Ardsley Partners Advanced Healthcare Fund, L.P. - 9,229,100
Ardsley Partners Fund II, L.P. - 1,520,900
Philip J. Hempleman - 10,750,000

**(iii) Sole power to dispose or to direct the disposition of:**

Ardsley Advisory Partners LP - 0
Ardsley Advisory Partners GP LLC - 0
Ardsley Partners I GP LLC - 0
Ardsley Partners Advanced Healthcare Fund, L.P. - 0
Ardsley Partners Fund II, L.P. - 0
Philip J. Hempleman - 0

**(iv) Shared power to dispose or to direct the disposition of:**

Ardsley Advisory Partners LP - 10,750,000
Ardsley Advisory Partners GP LLC - 10,750,000
Ardsley Partners I GP LLC - 10,750,000
Ardsley Partners Advanced Healthcare Fund, L.P. - 9,229,100
Ardsley Partners Fund II, L.P. - 1,520,900
Philip J. Hempleman - 10,750,000

**Item 5. Ownership of Five Percent or Less of a Class.**

[x] If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following.

**Item 6. Ownership of More than 5 Percent on Behalf of Another Person.**

Not Applicable

**Item 7. Identification and Classification of the Subsidiary**

Not Applicable

**Item 8. Identification and Classification of Members of the Group**

See Exhibit 2.

**Item 9. Notice of Dissolution of Group**

Not Applicable

**Item 10. Certification:**

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

### SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

**Ardsley Advisory Partners LP**

**Date:** 02/12/2026

**By:** /s/ Steve Napoli

**Name & Title:** Steve Napoli/ Member

**Ardsley Advisory Partners GP LLC**

**Date:** 02/12/2026

**By:** /s/ Steve Napoli

**Name & Title:** Steve Napoli/ Member

**Ardsley Partners I GP LLC**

**Date:** 02/12/2026

**By:** /s/ Steve Napoli

**Name & Title:** Steve Napoli/ Member

**Ardsley Partners Advanced Healthcare Fund, L.P.**

**Date:** 02/12/2026

**By:** /s/ Steve Napoli

**Name & Title:** Steve Napoli/ Member

**Ardsley Partners Fund II, L.P.**

**Date:** 02/12/2026

**By:** /s/ Steve Napoli

**Name & Title:** Steve Napoli/ Member

**Philip J. Hempleman**

**Date:** 02/12/2026

**By:** /s/ Steve Napoli*

**Name & Title:** Steve Napoli/Attorney-in Fact for Philip J. Hempleman