# EDGAR Filing Document

**Accession Number:** 0001357459
**File Stem:** 0001213900-23-009107
**Filing Date:** 2023-2
**Character Count:** 11800
**Document Hash:** 230e5bd2e12a9303eacc6c80f55e9d3d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-23-009107.hdr.sgml**: 20230208

**ACCESSION NUMBER**: 0001213900-23-009107

**CONFORMED SUBMISSION TYPE**: SC 13G/A

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230208

**DATE AS OF CHANGE**: 20230208

**GROUP MEMBERS**: DANIEL B. ASHER

**GROUP MEMBERS**: MITCHELL P. KOPIN

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PALISADE BIO, INC.
- **CENTRAL INDEX KEY:** 0001357459
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 522007292
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-86724
- **FILM NUMBER:** 23596929

**BUSINESS ADDRESS:**
- **STREET 1:** 7750 EL CAMINO REAL, SUITE 5200
- **CITY:** CARLSBAD
- **STATE:** CA
- **ZIP:** 92009
- **BUSINESS PHONE:** (858) 704-4900

**MAIL ADDRESS:**
- **STREET 1:** 7750 EL CAMINO REAL, SUITE 5200
- **CITY:** CARLSBAD
- **STATE:** CA
- **ZIP:** 92009

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Seneca Biopharma, Inc.
- **DATE OF NAME CHANGE:** 20200127

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Neuralstem, Inc.
- **DATE OF NAME CHANGE:** 20060324
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** INTRACOASTAL CAPITAL, LLC
- **CENTRAL INDEX KEY:** 0001646799
- **IRS NUMBER:** 320460881
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13G/A

**BUSINESS ADDRESS:**
- **STREET 1:** 245 PALM TRAIL
- **CITY:** DELRAY BEACH
- **STATE:** FL
- **ZIP:** 33483
- **BUSINESS PHONE:** 8475629030

**MAIL ADDRESS:**
- **STREET 1:** 245 PALM TRAIL
- **CITY:** DELRAY BEACH
- **STATE:** FL
- **ZIP:** 33483

**UNITED STATES<br> SECURITIES AND EXCHANGE COMMISSION<br> Washington, D.C. 20549**

**SCHEDULE 13G** 

**Under the Securities Exchange Act of 1934** 

**(Amendment No. 1)\***

Palisade Bio, Inc.

(Name of Issuer)

Common Stock, $0.01 par value per share

(Title of Class of Securities)

696389204

(CUSIP Number)

December 31, 2022

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

a. ☐
Rule 13d-1(b)

b. ☒
Rule 13d-1(c)

c. ☐
Rule 13d-1(d)

\* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Page 1 of 6

CUSIP No. 696389204 <br>

---

| | |
|:---|:---|
| 1. | Names of Reporting Persons. |
|  | Mitchell P. Kopin |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) |
|  | (b) |

---

3. SEC Use Only

4. Citizenship
or Place of Organization United States of America

---

| | | |
|:---|:---|:---|
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 5. Sole Voting Power | 0 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 6. Shared Voting Power | 131,086 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 7. Sole Dispositive Power | 0 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 8. Shared Dispositive Power | 131,086 |

---

---

| | |
|:---|:---|
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person 131,086 (see Item 4) |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) |
| 11. | Percent of Class Represented by Amount in Row (9) 5.7% (see Item 4) |
| 12. | Type of Reporting Person (See Instructions) |
|  | IN; HC |

---

Page 2 of 6

CUSIP No. <u>696389204</u>

---

| | |
|:---|:---|
| 1. | Names of Reporting Persons. |
|  | Daniel B. Asher |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) |
|  | (b) |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization United States of America |

---

---

| | | |
|:---|:---|:---|
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 5. Sole Voting Power | 0 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 6. Shared Voting Power | 131,086 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 7. Sole Dispositive Power | 0 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 8. Shared Dispositive Power | 131,086 |

---

---

| | |
|:---|:---|
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person 131,086 (see Item 4) |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) |
| 11. | Percent of Class Represented by Amount in Row (9) 5.7% (see Item 4) |
| 12. | Type of Reporting Person (See Instructions) |
|  | IN; HC |

---

Page 3 of 6

CUSIP No. <u>696389204 </u>

---

| | |
|:---|:---|
| 1. | Names of Reporting Persons. |
|  | Intracoastal Capital LLC |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions) |
|  | (a) |
|  | (b) |
| 3. | SEC Use Only |
| 4. | Citizenship or Place of Organization Delaware |

---

---

| | | |
|:---|:---|:---|
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 5. Sole Voting Power | 0 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 6. Shared Voting Power | 131,086 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 7. Sole Dispositive Power | 0 |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | | |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: |  |  |
| Number of <br> Shares Beneficially<br> Owned by Each<br> Reporting Person<br> With: | 8. Shared Dispositive Power | 131,086<br>|

---

---

| | |
|:---|:---|
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person 131,086 (see Item 4) |
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) |
| 11. | Percent of Class Represented by Amount in Row (9) 5.7% (see Item 4) |
| 12. | Type of Reporting Person (See Instructions) |
|  | OO |

---

Page 4 of 6

This Amendment No. 1 is being filed jointly by the Reporting Persons and amends the Schedule 13G initially filed by the Reporting Persons with the Securities and Exchange Commission (the "**SEC**") on August 22, 2022 (the "**Schedule 13G**").

Except as set forth below, all Items of the Schedule 13G remain unchanged. All capitalized terms not otherwise defined herein shall have the meanings ascribed to such terms in the Schedule 13G.

**Item 2.** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e) CUSIP Number

696389204

 **Item 4. Ownership.** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) and (b):

As of close of business on December 31, 2022, each of the Reporting Persons may have been deemed to have beneficial ownership of 131,086 shares of Common Stock, which consisted of (i) 52,000 shares of Common Stock held by Intracoastal, (ii) 3,086 shares of Common Stock issuable upon an exercise of a warrant held by Intracoastal ("**Intracoastal Warrant 1**"), (ii) 64,000 shares of Common Stock issuable upon an exercise of a second warrant held by Intracoastal ("**Intracoastal Warrant 2**") and (iii) 12,000 shares of Common Stock issuable upon an exercise of a third warrant held by Intracoastal ("**Intracoastal Warrant 3**"), and all such shares of Common Stock in the aggregate represented beneficial ownership of approximately 5.7% of the Common Stock, based on (1) 2,188,308 shares of Common Stock outstanding as of September 30, 2022, as reported by the Issuer, (2) 3,086 shares of Common Stock issuable upon an exercise of Intracoastal Warrant 1, (3) 64,000 shares of Common Stock issuable upon an exercise of Intracoastal Warrant 2 and (4) 12,000 shares of Common Stock issuable upon an exercise of Intracoastal Warrant 3.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) Number of shares as to which each Reporting Person has:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) Sole power to vote or to direct the vote: <u>0</u> .

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii) Shared power to vote or to direct the vote: <u>131,086</u> .

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii) Sole power to dispose or to direct the disposition of <u>0</u> .

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iv) Shared power to dispose or to direct the disposition of <u>131,086</u> .

**Item 10. Certification** 

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a-11.

Page 5 of 6

**SIGNATURE**

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: February 8, 2023

---

| | |
|:---|:---|
| /s/ Mitchell P. Kopin | /s/ Mitchell P. Kopin |
| Mitchell P. Kopin | Mitchell P. Kopin |
| /s/ Daniel B. Asher | /s/ Daniel B. Asher |
| Daniel B. Asher | Daniel B. Asher |
| Intracoastal Capital LLC | Intracoastal Capital LLC |
| By: | /s/ Mitchell P. Kopin |
|  | Mitchell P. Kopin, Manager |

---

Page 6 of 6