# EDGAR Filing Document

**Accession Number:** 0001414040
**File Stem:** 0001752724-25-183430
**Filing Date:** 2025-7
**Character Count:** 43772
**Document Hash:** 3d41835242996b4ef9c847aada953b1e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-25-183430.hdr.sgml**: 20250730

**ACCESSION NUMBER**: 0001752724-25-183430

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250531

**FILED AS OF DATE**: 20250730

**DATE AS OF CHANGE**: 20250730

**PERIOD START**: 20251130

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ALPS ETF Trust
- **CENTRAL INDEX KEY:** 0001414040

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **FISCAL YEAR END:** 1130

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-22175
- **FILM NUMBER:** 251165213

**BUSINESS ADDRESS:**
- **STREET 1:** P.O. Box 328
- **CITY:** Denver
- **STATE:** CO
- **ZIP:** 80201-0328
- **BUSINESS PHONE:** 303.623.2577

**MAIL ADDRESS:**
- **STREET 1:** P.O. Box 328
- **CITY:** Denver
- **STATE:** CO
- **ZIP:** 80201-0328

## Series and Classes Contracts Data

### ALPS Medical Breakthroughs ETF (Series ID: S000047823)

| Class ID   | Class Name                     | Ticker Symbol   |
|:---|:---|:---|
| C000150206 | ALPS Medical Breakthroughs ETF | SBIO            |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ALPS ETF TRUST

- **b. Investment Company Act file number:** 811-22175

- **c. CIK number of Registrant:** 0001414040

- **d. LEI of Registrant:** 549300VF1907NYC4WM31

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 1290 BROADWAY SUITE 1000

  - **City:** DENVER

  - **State:** CO

  - **Foreign country:** US

  - **Zip / Postal Code:** 80203

  - **Telephone number:** 3036232577

**Item A.2. Information about the Series.**

- **a. Name of Series:** ALPS Medical Breakthroughs ETF

- **b. EDGAR series identifier (if any):** S000047823

- **c. LEI of Series:** 549300UUE13R3N0UVB96

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-11-30

- **b. Date as of which information is reported:** 2025-05-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $81230915.72

**Total Liabilities:** $34291.80

**Net Assets:** $81196623.92

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000150206 | -9.09%               | 4.03%                | -2.23%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-82704.92               | $-8178480.43                               |
| Month 2  | $236097.30               | $3033304.26                                |
| Month 3  | $-270619.81              | $-1628355.24                               |

### Schedule of Portfolio Investments

| Name                                                       | Title                                                                       | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Protagonist Therapeutics Inc                               | Protagonist Therapeutics, Inc.                                              | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45188 | NS      | $2145074.36   | 2.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunocore Holdings Plc                                    | Immunocore Holdings PLC                                                     | CUSIP: 45258D105<br>LEI: 213800IUE3DFS84BVN18 | Long             | EC               | CORP              | GB        |     35097 | NS      | $1284550.20   | 1.58%             |  |  |  | No            |                  1 | On Loan: —       |
| Novavax Inc                                                | Novavax, Inc.                                                               | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |    111242 | NS      | $816516.28    | 1.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Nuvation Bio Inc                                           | Nuvation Bio, Inc.                                                          | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    239661 | NS      | $508081.32    | 0.63%             |  |  |  | No            |                  1 | On Loan: —       |
| N/A                                                        | Azn Ln - Cvr                                                                | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               | CORP              | GB        |     29054 | NC      | $0.04         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Rigel Pharmaceuticals Inc                                  | Rigel Pharmaceuticals, Inc.                                                 | CUSIP: 766559702<br>LEI: 529900KPTNUS5J8K9K66 | Long             | EC               | CORP              | US        |     12757 | NS      | $244934.40    | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Prokidney Corp                                             | ProKidney Corp.                                                             | CUSIP: G7S53R104<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |     92690 | NS      | $66996.33     | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Aurinia Pharmaceuticals Inc                                | Aurinia Pharmaceuticals, Inc.                                               | CUSIP: 05156V102<br>LEI: 5299008YP2BW4570ML28 | Long             | EC               | CORP              | CA        |     96765 | NS      | $758637.60    | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Viridian Therapeutics Inc                                  | Viridian Therapeutics, Inc.                                                 | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |     59869 | NS      | $833376.48    | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Pliant Therapeutics Inc                                    | Pliant Therapeutics, Inc.                                                   | CUSIP: 729139105<br>LEI: 5493002Q5LITR7VHZH02 | Long             | EC               | CORP              | US        |     44069 | NS      | $59493.15     | 0.07%             |  |  |  | No            |                  1 | On Loan: —       |
| Celldex Therapeutics Inc                                   | Celldex Therapeutics, Inc.                                                  | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |     48830 | NS      | $965857.40    | 1.19%             |  |  |  | No            |                  1 | On Loan: —       |
| Agios Pharmaceuticals Inc                                  | Agios Pharmaceuticals, Inc.                                                 | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     41314 | NS      | $1325766.26   | 1.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Anaptysbio Inc                                             | AnaptysBio, Inc.                                                            | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |     22522 | NS      | $500664.06    | 0.62%             |  |  |  | No            |                  1 | On Loan: —       |
| Chinook Therapeutics Inc                                   | Chinook Therapeutics, Inc.                                                  | CUSIP: N/A<br>LEI: 549300X0O3003W5QYQ48       | N/A              | DE               | CORP              | US        |     20700 | NC      | $0.02         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Iteos Therapeutics Inc                                     | iTeos Therapeutics, Inc.                                                    | CUSIP: 46565G104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     27898 | NS      | $279537.96    | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc                             | Day One Biopharmaceuticals, Inc.                                            | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     71424 | NS      | $455685.12    | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Tarsus Pharmaceuticals Inc                                 | Tarsus Pharmaceuticals, Inc.                                                | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     27307 | NS      | $1172835.65   | 1.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc                             | Praxis Precision Medicines, Inc.                                            | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     14548 | NS      | $560825.40    | 0.69%             |  |  |  | No            |                  1 | On Loan: —       |
| Y-mabs Therapeutics Inc                                    | Y-mAbs Therapeutics, Inc.                                                   | CUSIP: 984241109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     32429 | NS      | $149173.40    | 0.18%             |  |  |  | No            |                  1 | On Loan: —       |
| Mbx Biosciences Inc                                        | MBX Biosciences, Inc.                                                       | CUSIP: 55287L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     25353 | NS      | $314884.26    | 0.39%             |  |  |  | No            |                  1 | On Loan: —       |
| Ideaya Biosciences Inc                                     | Ideaya Biosciences, Inc.                                                    | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |     60074 | NS      | $1194871.86   | 1.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corp Plc                                          | Prothena Corp. PLC                                                          | CUSIP: G72800108<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | IE        |     36962 | NS      | $169655.58    | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Omniab Inc                                                 | OmniAb, Inc.                                                                | CUSIP: 68218J301<br>LEI: N/A                  | N/A              | DE               | CORP              | US        |      3653 | NC      | $0.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Moonlake Immunotherapeutics                                | MoonLake Immunotherapeutics                                                 | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |     46068 | NS      | $1797112.68   | 2.21%             |  |  |  | No            |                  1 | On Loan: —       |
| Intellia Therapeutics Inc                                  | Intellia Therapeutics, Inc.                                                 | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |     75304 | NS      | $517338.48    | 0.64%             |  |  |  | No            |                  1 | On Loan: —       |
| Zai Lab Ltd                                                | Zai Lab, Ltd.                                                               | CUSIP: 98887Q104<br>LEI: 549300P2UYQ9U5LY1T58 | Long             | EC               | CORP              | KY        |     74601 | NS      | $2248474.14   | 2.77%             |  |  |  | No            |                  1 | On Loan: —       |
| Ironwood Pharmaceuticals Inc                               | Ironwood Pharmaceuticals, Inc.                                              | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |    113801 | NS      | $68178.18     | 0.08%             |  |  |  | No            |                  1 | On Loan: —       |
| Cartesian Therapeutics Inc                                 | Cartesian Therapeutics, Inc.                                                | CUSIP: 816212302<br>LEI: 529900NMN0LACZOL7C43 | Long             | EC               | CORP              | US        |     18885 | NS      | $180540.60    | 0.22%             |  |  |  | No            |                  1 | On Loan: —       |
| Liquidia Corp                                              | Liquidia Corp.                                                              | CUSIP: 53635D202<br>LEI: 549300O826O5VQJTG707 | Long             | EC               | CORP              | US        |     61017 | NS      | $910373.64    | 1.12%             |  |  |  | No            |                  1 | On Loan: —       |
| Rapport Therapeutics Inc                                   | Rapport Therapeutics, Inc.                                                  | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     25443 | NS      | $210413.61    | 0.26%             |  |  |  | No            |                  1 | On Loan: —       |
| Stoke Therapeutics Inc                                     | Stoke Therapeutics, Inc.                                                    | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |     38848 | NS      | $370609.92    | 0.46%             |  |  |  | No            |                  1 | On Loan: —       |
| Crinetics Pharmaceuticals Inc                              | Crinetics Pharmaceuticals, Inc.                                             | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |     65741 | NS      | $2005757.91   | 2.47%             |  |  |  | No            |                  1 | On Loan: —       |
| Merus Nv                                                   | Merus NV                                                                    | CUSIP: N5749R100<br>LEI: 549300W8GPUWU8QNU293 | Long             | EC               | CORP              | NL        |     49884 | NS      | $2796995.88   | 3.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Compass Pathways Plc                                       | Compass Pathways PLC                                                        | CUSIP: 20451W101<br>LEI: 213800N7CUZIC6QSTZ31 | Long             | EC               | CORP              | GB        |     64499 | NS      | $268315.84    | 0.33%             |  |  |  | No            |                  1 | On Loan: —       |
| Axsome Therapeutics Inc                                    | Axsome Therapeutics, Inc.                                                   | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |     31657 | NS      | $3329050.12   | 4.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Arrivent Biopharma Inc                                     | ArriVent Biopharma, Inc.                                                    | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     24509 | NS      | $520816.25    | 0.64%             |  |  |  | No            |                  1 | On Loan: —       |
| Pharvaris Nv                                               | Pharvaris NV                                                                | CUSIP: N69605108<br>LEI: 9845003BE146D3B75D32 | Long             | EC               | CORP              | NL        |     35675 | NS      | $592205.00    | 0.73%             |  |  |  | No            |                  1 | On Loan: —       |
| Biocryst Pharmaceuticals Inc                               | BioCryst Pharmaceuticals, Inc.                                              | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    149580 | NS      | $1607985.00   | 1.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Vir Biotechnology Inc                                      | Vir Biotechnology, Inc.                                                     | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    100138 | NS      | $494681.72    | 0.61%             |  |  |  | No            |                  1 | On Loan: —       |
| Amylyx Pharmaceuticals Inc                                 | Amylyx Pharmaceuticals, Inc.                                                | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     65829 | NS      | $339019.35    | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Sutro Biopharma Inc                                        | Sutro Biopharma, Inc.                                                       | CUSIP: 869367102<br>LEI: 5493005U6P15VD25P851 | Long             | EC               | CORP              | US        |     59610 | NS      | $53511.90     | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Alector Inc                                                | Alector, Inc.                                                               | CUSIP: 014442107<br>LEI: 549300Z8RQOIY1JMHC25 | Long             | EC               | CORP              | US        |     72973 | NS      | $97054.09     | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Newamsterdam Pharma Co Nv                                  | Newamsterdam Pharma Co. NV                                                  | CUSIP: N62509109<br>LEI: 984500B6549TF6E14D36 | Long             | EC               | CORP              | NL        |     76222 | NS      | $1380380.42   | 1.70%             |  |  |  | No            |                  1 | On Loan: No      |
| Zenas Biopharma Inc                                        | Zenas Biopharma, Inc.                                                       | CUSIP: 98937L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     27396 | NS      | $260809.92    | 0.32%             |  |  |  | No            |                  1 | On Loan: —       |
| Enanta Pharmaceuticals Inc                                 | Enanta Pharmaceuticals, Inc.                                                | CUSIP: 29251M106<br>LEI: 529900SSN4DODDQSN594 | Long             | EC               | CORP              | US        |     15831 | NS      | $93877.83     | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Aclaris Therapeutics Inc                                   | Aclaris Therapeutics, Inc.                                                  | CUSIP: 00461U105<br>LEI: 5493000B2LQ9QTW1DF52 | Long             | EC               | CORP              | US        |     76720 | NS      | $112011.20    | 0.14%             |  |  |  | No            |                  1 | On Loan: —       |
| Fulgent Genetics Inc                                       | Fulgent Genetics, Inc.                                                      | CUSIP: 359664109<br>LEI: 549300CL6P01M68QJ404 | Long             | EC               | CORP              | US        |     22157 | NS      | $459093.04    | 0.57%             |  |  |  | No            |                  1 | On Loan: —       |
| Mannkind Corp                                              | MannKind Corp.                                                              | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |    215007 | NS      | $892279.05    | 1.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunome Inc                                               | Immunome, Inc.                                                              | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     60908 | NS      | $533554.08    | 0.66%             |  |  |  | No            |                  1 | On Loan: —       |
| Avidity Biosciences Inc                                    | Avidity Biosciences, Inc.                                                   | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     85552 | NS      | $2650400.96   | 3.26%             |  |  |  | No            |                  1 | On Loan: —       |
| Macrogenics Inc                                            | MacroGenics, Inc.                                                           | CUSIP: 556099109<br>LEI: 5493001KJQUA83L8MH79 | Long             | EC               | CORP              | US        |     47373 | NS      | $64427.28     | 0.08%             |  |  |  | No            |                  1 | On Loan: —       |
| Upstream Bio Inc                                           | Upstream Bio, Inc.                                                          | CUSIP: 91678A107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     38055 | NS      | $351247.65    | 0.43%             |  |  |  | No            |                  1 | On Loan: —       |
| Celcuity Inc                                               | Celcuity, Inc.                                                              | CUSIP: 15102K100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     28044 | NS      | $298107.72    | 0.37%             |  |  |  | No            |                  1 | On Loan: —       |
| Vanda Pharmaceuticals Inc                                  | Vanda Pharmaceuticals, Inc.                                                 | CUSIP: 921659108<br>LEI: 529900AY8VOOQBKJ0O70 | Long             | EC               | CORP              | US        |     40894 | NS      | $177479.96    | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Eledon Pharmaceuticals Inc                                 | Eledon Pharmaceuticals, Inc.                                                | CUSIP: 28617K101<br>LEI: 549300S17CAM13O43606 | Long             | EC               | CORP              | US        |     43269 | NS      | $129807.00    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Astrazeneca Plc                                            | AstraZeneca PLC                                                             | CUSIP: N/A<br>LEI: PY6ZZQWO2IZFZC3IOL08       | N/A              | DE               | CORP              | US        |     36586 | NC      | $0.04         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Astria Therapeutics Inc                                    | Astria Therapeutics, Inc.                                                   | CUSIP: 04635X102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     42306 | NS      | $201376.56    | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc                                 | Rhythm Pharmaceuticals, Inc.                                                | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |     45222 | NS      | $2773465.26   | 3.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Verona Pharma Plc                                          | Verona Pharma PLC                                                           | CUSIP: 925050106<br>LEI: 213800EVI6O6J3TIAL06 | Long             | EC               | CORP              | GB        |     58904 | NS      | $4783004.80   | 5.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Vera Therapeutics Inc                                      | Vera Therapeutics, Inc.                                                     | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45295 | NS      | $858340.25    | 1.06%             |  |  |  | No            |                  1 | On Loan: —       |
| Replimune Group Inc                                        | Replimune Group, Inc.                                                       | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |     54854 | NS      | $492588.92    | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Capricor Therapeutics Inc                                  | Capricor Therapeutics, Inc.                                                 | CUSIP: 14070B309<br>LEI: 5493002ZI5PDLXV4DX14 | Long             | EC               | CORP              | US        |     32359 | NS      | $320030.51    | 0.39%             |  |  |  | No            |                  1 | On Loan: —       |
| Mirum Pharmaceuticals Inc                                  | Mirum Pharmaceuticals, Inc.                                                 | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |     34688 | NS      | $1542228.48   | 1.90%             |  |  |  | No            |                  1 | On Loan: —       |
| Zentalis Pharmaceuticals Inc                               | Zentalis Pharmaceuticals, Inc.                                              | CUSIP: 98943L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     53595 | NS      | $64849.95     | 0.08%             |  |  |  | No            |                  1 | On Loan: —       |
| Disc Medicine Inc                                          | Disc Medicine, Inc.                                                         | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     24912 | NS      | $1162892.16   | 1.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Akero Therapeutics Inc                                     | Akero Therapeutics, Inc.                                                    | CUSIP: 00973Y108<br>LEI: 549300SI3KG74LBE2955 | Long             | EC               | CORP              | US        |     56780 | NS      | $2819127.00   | 3.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Aura Biosciences Inc                                       | Aura Biosciences, Inc.                                                      | CUSIP: 05153U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     36190 | NS      | $212073.40    | 0.26%             |  |  |  | No            |                  1 | On Loan: —       |
| Omniab Inc                                                 | OmniAb, Inc.                                                                | CUSIP: 68218J202<br>LEI: N/A                  | N/A              | DE               | CORP              | US        |      3653 | NC      | $0.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Cg Oncology Inc                                            | CG oncology, Inc.                                                           | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     55122 | NS      | $1412225.64   | 1.74%             |  |  |  | No            |                  1 | On Loan: —       |
| Keros Therapeutics Inc                                     | Keros Therapeutics, Inc.                                                    | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     28956 | NS      | $409727.40    | 0.50%             |  |  |  | No            |                  1 | On Loan: —       |
| Tourmaline Bio Inc                                         | Tourmaline Bio, Inc.                                                        | CUSIP: 89157D105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     17042 | NS      | $284260.56    | 0.35%             |  |  |  | No            |                  1 | On Loan: —       |
| Edgewise Therapeutics Inc                                  | Edgewise Therapeutics, Inc.                                                 | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     66498 | NS      | $949591.44    | 1.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp                                  | Anavex Life Sciences Corp.                                                  | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |     58644 | NS      | $441589.32    | 0.54%             |  |  |  | No            |                  1 | On Loan: —       |
| State Street Institutional Treasury Plus Money Market Fund | State Street Institutional Treasury Plus Money Market Fund                  | CUSIP: 857492862<br>LEI: 549300PNASLVKQG64331 | Long             | STIV             | RF                | US        |    130293 | NS      | $130293.24    | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Ptc Therapeutics Inc                                       | PTC Therapeutics, Inc.                                                      | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |     56067 | NS      | $2720370.84   | 3.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                                               | Rezolute, Inc.                                                              | CUSIP: 76200L309<br>LEI: 549300T05L48T72P2G08 | Long             | EC               | CORP              | US        |     41945 | NS      | $172813.40    | 0.21%             |  |  |  | No            |                  1 | On Loan: —       |
| Amicus Therapeutics Inc                                    | Amicus Therapeutics, Inc.                                                   | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |    217037 | NS      | $1317414.59   | 1.62%             |  |  |  | No            |                  1 | On Loan: No      |
| Galapagos Nv                                               | Galapagos NV                                                                | CUSIP: 36315X101<br>LEI: 549300QKJ78IY0IOV655 | Long             | EC               | CORP              | BE        |     47222 | NS      | $1358104.72   | 1.67%             |  |  |  | No            |                  1 | On Loan: —       |
| Apogee Therapeutics Inc                                    | Apogee Therapeutics, Inc.                                                   | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     32429 | NS      | $1188198.56   | 1.46%             |  |  |  | No            |                  1 | On Loan: —       |
| Neumora Therapeutics Inc                                   | Neumora Therapeutics, Inc.                                                  | CUSIP: 640979100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    111378 | NS      | $79780.06     | 0.10%             |  |  |  | No            |                  1 | On Loan: —       |
| Olema Pharmaceuticals Inc                                  | Olema Pharmaceuticals, Inc.                                                 | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49163 | NS      | $259580.64    | 0.32%             |  |  |  | No            |                  1 | On Loan: —       |
| Aldeyra Therapeutics Inc                                   | Aldeyra Therapeutics, Inc.                                                  | CUSIP: 01438T106<br>LEI: 529900HGKY864E4Y9014 | Long             | EC               | CORP              | US        |     42656 | NS      | $91710.40     | 0.11%             |  |  |  | No            |                  1 | On Loan: —       |
| Xencor Inc                                                 | Xencor, Inc.                                                                | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |     50111 | NS      | $400888.00    | 0.49%             |  |  |  | No            |                  1 | On Loan: —       |
| Larimar Therapeutics Inc                                   | Larimar Therapeutics, Inc.                                                  | CUSIP: 517125100<br>LEI: 529900NCBZHTTJV6HX73 | Long             | EC               | CORP              | US        |     46227 | NS      | $104010.75    | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes Plc                                               | Alkermes PLC                                                                | CUSIP: G01767105<br>LEI: N/A                  | Long             | EC               | CORP              | IE        |    113203 | NS      | $3465143.83   | 4.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc                                  | Dianthus Therapeutics, Inc.                                                 | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |     23065 | NS      | $401100.35    | 0.49%             |  |  |  | No            |                  1 | On Loan: —       |
| Arcus Biosciences Inc                                      | Arcus Biosciences, Inc.                                                     | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     75090 | NS      | $670553.70    | 0.83%             |  |  |  | No            |                  1 | On Loan: —       |
| Autolus Therapeutics Plc                                   | Autolus Therapeutics PLC                                                    | CUSIP: 05280R100<br>LEI: 549300C0KZP8EYROLL02 | Long             | EC               | CORP              | GB        |    194483 | NS      | $340345.25    | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcturus Therapeutics Holdings Inc                         | Arcturus Therapeutics Holdings, Inc.                                        | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     19427 | NS      | $243420.31    | 0.30%             |  |  |  | No            |                  1 | On Loan: —       |
| Mineralys Therapeutics Inc                                 | Mineralys Therapeutics, Inc.                                                | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     33757 | NS      | $525934.06    | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Xenon Pharmaceuticals Inc                                  | Xenon Pharmaceuticals, Inc.                                                 | CUSIP: 98420N105<br>LEI: 549300XV44Q9Z1MIPQ03 | Long             | EC               | CORP              | CA        |     54085 | NS      | $1560352.25   | 1.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Theravance Biopharma Inc                                   | Theravance Biopharma, Inc.                                                  | CUSIP: G8807B106<br>LEI: 5493007VTSXP4Z6MIW52 | Long             | EC               | CORP              | KY        |     35136 | NS      | $321845.76    | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Cargo Therapeutics Inc                                     | Cargo Therapeutics, Inc.                                                    | CUSIP: 14179K101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     32291 | NS      | $137236.75    | 0.17%             |  |  |  | No            |                  1 | On Loan: —       |
| Vericel Corp                                               | Vericel Corp.                                                               | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |     35376 | NS      | $1460851.92   | 1.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Erasca Inc                                                 | Erasca, Inc.                                                                | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    204768 | NS      | $286675.20    | 0.35%             |  |  |  | No            |                  1 | On Loan: —       |
| 4d Molecular Therapeutics Inc                              | 4D Molecular Therapeutics, Inc.                                             | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     31952 | NS      | $115666.24    | 0.14%             |  |  |  | No            |                  1 | On Loan: —       |
| Annexon Inc                                                | Annexon, Inc.                                                               | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     80464 | NS      | $164146.56    | 0.20%             |  |  |  | No            |                  1 | On Loan: —       |
| N/A                                                        | State Street Navigator Securities Lending Government Money Market Portfolio | CUSIP: N/A<br>LEI: N/A                        | Long             | STIV             | RF                | US        |         0 | NS      | $0.00         | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Structure Therapeutics Inc                                 | Structure Therapeutics, Inc.                                                | CUSIP: 86366E106<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |     42251 | NS      | $919381.76    | 1.13%             |  |  |  | No            |                  1 | On Loan: —       |
| N/A                                                        | Radius Health CVR                                                           | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               | CORP              | US        |     28640 | NC      | $0.03         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Kyverna Therapeutics Inc                                   | Kyverna Therapeutics, Inc.                                                  | CUSIP: 501976104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     31307 | NS      | $79832.85     | 0.10%             |  |  |  | No            |                  1 | On Loan: —       |
| Denali Therapeutics Inc                                    | Denali Therapeutics, Inc.                                                   | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |    108960 | NS      | $1442630.40   | 1.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara Inc                                                 | Savara, Inc.                                                                | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |    112723 | NS      | $257008.44    | 0.32%             |  |  |  | No            |                  1 | On Loan: —       |
| Urogen Pharma Ltd                                          | UroGen Pharma, Ltd.                                                         | CUSIP: M96088105<br>LEI: 549300C0YCX7CG2G5D50 | Long             | EC               | CORP              | IL        |     31904 | NS      | $135272.96    | 0.17%             |  |  |  | No            |                  1 | On Loan: —       |
| Acadia Pharmaceuticals Inc                                 | ACADIA Pharmaceuticals, Inc.                                                | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |    116710 | NS      | $2517434.70   | 3.10%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-06-30

**Name of Applicant:** ALPS ETF TRUST

**Signature:** Erich Rettinger

**Name of Signer:** Erich Rettinger

**Title:** Treasurer