# EDGAR Filing Document

**Accession Number:** 0002012593
**File Stem:** 0001193125-26-171836
**Filing Date:** 2026-4
**Character Count:** 5707
**Document Hash:** 9f297dea3dddaa53f7b3ab4ef82b9a15
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-171836.hdr.sgml**: 20260423

**ACCESSION NUMBER**: 0001193125-26-171836

**CONFORMED SUBMISSION TYPE**: DEFA14A

**PUBLIC DOCUMENT COUNT**: 7

**FILED AS OF DATE**: 20260423

**DATE AS OF CHANGE**: 20260423

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Rapport Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0002012593
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 880724208
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DEFA14A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-42121
- **FILM NUMBER:** 26885543

**BUSINESS ADDRESS:**
- **STREET 1:** 99 HIGH STREET
- **STREET 2:** SUITE 2100
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02110
- **BUSINESS PHONE:** 857-321-8020

**MAIL ADDRESS:**
- **STREET 1:** 99 HIGH STREET
- **STREET 2:** SUITE 2100
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02110

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**Washington, D.C. 20549** 

**SCHEDULE 14A** 

**Proxy Statement Pursuant to Section 14(a) of the** 

**Securities Exchange Act of 1934** 

**(Amendment No.)** 

Filed by the Registrant ☒

Filed by a Party other than the Registrant ☐

Check the appropriate box:

☐ Preliminary Proxy Statement

☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

☐ Definitive Proxy Statement

☒ **Definitive Additional Materials** 

☐ Soliciting Material under §240.14a-12

**RAPPORT THERAPEUTICS, INC.** 

**(Name of Registrant as Specified in Its Charter)** 

**(Name of Person(s) Filing Proxy Statement, if other than the Registrant)** 

Payment of Filing Fee (Check all boxes that apply):

☒ No fee required

☐ Fee paid previously with preliminary materials

☐ Fee computed on table in exhibit required by Item 25(b) Exchange Act Rules 14a-6(i)(1) and 0-11

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![LOGO](g96029dsp03.jpg)

RAPPORT THERAPEUTICS, INC.

99 HIGH STREET, SUITE 2100

BOSTON, MA 02110

V89959-P44732

![LOGO](g96029g00i01.jpg)

You invested in RAPPORT THERAPEUTICS, INC. and it's time to vote!

You have the right to vote on proposals being presented at the 2026 Annual Meeting, which is being held virtually. **Important Notice Regarding the Availability of Proxy Materials for the 2026 Annual Meeting of Stockholders to be Held on June 10, 2026.**

Get informed before you vote

View the Notice, Proxy Statement and 2025 Annual Report online OR you can receive a free paper or email copy of the material(s) by requesting prior to May 27, 2026. If you would like to request a copy of the material(s) for this and/or future stockholder meetings, you may (1) visit www.ProxyVote.com, (2) call 1-800-579-1639 or (3) send an email to sendmaterial@proxyvote.com. If sending an email, please include your control number (indicated below) in the subject line. Unless requested, you will not otherwise receive a paper or email copy.

![LOGO](g96029dsp03b.jpg)

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| | | |
|:---|:---|:---|
| **Smartphone users** | ![LOGO](g96029dsp03d.jpg) | **Vote Virtually at the Meeting\*** |
| <br> Point your camera here and<br> vote without entering a<br> control number | ![LOGO](g96029dsp03d.jpg) | June 10, 2026 |
| <br> Point your camera here and<br> vote without entering a<br> control number | ![LOGO](g96029dsp03d.jpg) | 1:00 PM ET |
| <br> Point your camera here and<br> vote without entering a<br> control number | ![LOGO](g96029dsp03d.jpg) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ![LOGO](g96029dsp03c.jpg)  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Virtually at: | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Virtually at: |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ![LOGO](g96029dsp03c.jpg)  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;www.virtualshareholdermeeting.com/RAPP2026 | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;www.virtualshareholdermeeting.com/RAPP2026 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ![LOGO](g96029dsp03c.jpg)  |  |  |

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\*Please check the meeting materials for any special requirements for meeting attendance.

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**Vote at www.ProxyVote.com** 

**THIS IS NOT A VOTABLE BALLOT** 

This is an overview of the proposals being presented at the

upcoming 2026 Annual Meeting. Please follow the instructions

on the reverse side to vote on these important matters.

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| | | |
|:---|:---|:---|
| **Voting Items** | **Voting Items** | **Board**<br> **Recommends** |
| 1. | To elect James Healy, M.D., Ph.D., Robert J. Perez, and Raymond Sanchez, M.D. as Class II Directors. |  |
|  | **Nominees:** |  |
|  | 01) James Healy, M.D., Ph.D.<br> 02) Robert J. Perez<br> 03) Raymond Sanchez, M.D. | **![LOGO](g96029dsp4b.jpg) For** |
| 2. | To ratify the appointment of PricewaterhouseCoopers LLP as Rapport's independent registered public accounting firm for the fiscal year ending December 31, 2026. | **![LOGO](g96029dsp4b.jpg) For** |
|  **NOTE:** In their discretion, the proxies are authorized to vote upon such other business as may properly come before the meeting or any continuations, adjournments and postponements thereof. | **NOTE:** In their discretion, the proxies are authorized to vote upon such other business as may properly come before the meeting or any continuations, adjournments and postponements thereof. |  |

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Prefer to receive an email instead? While voting on www.ProxyVote.com, be sure to click "Delivery Settings".

V89960-P44732