# EDGAR Filing Document

**Accession Number:** 0001335325
**File Stem:** 0001172661-26-002079
**Filing Date:** 2026-5
**Character Count:** 19211
**Document Hash:** ab82805f4531ec1ce55d3531ef629ed2
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001172661-26-002079.hdr.sgml**: 20260515

**ACCESSION NUMBER**: 0001172661-26-002079

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260515

**DATE AS OF CHANGE**: 20260515

**EFFECTIVENESS DATE**: 20260515

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** HighVista Strategies LLC
- **CENTRAL INDEX KEY:** 0001335325

**ORGANIZATION NAME:**
- **EIN:** 830423786
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-14212
- **FILM NUMBER:** 26983362

**BUSINESS ADDRESS:**
- **STREET 1:** 200 CLARENDON STREET, 50TH FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116
- **BUSINESS PHONE:** 617-406-6500

**MAIL ADDRESS:**
- **STREET 1:** 200 CLARENDON STREET, 50TH FLOOR
- **CITY:** BOSTON
- **STATE:** MA
- **ZIP:** 02116

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 03-31-2026

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** HighVista Strategies LLC<br>**Address:** 200 CLARENDON STREET 50TH FLOOR<br>BOSTON, MA 02116

**Form 13F File Number:** 028-14212

**CRD Number (if applicable):** 000155759

**SEC File Number (if applicable):** 801-73524

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Nicholas Boston<br>**Title:** Chief Compliance Officer<br>**Phone:** 617-406-6546

**Signature, Place, and Date of Signing:**

/s/ Nicholas Boston  Boston, MA  05-15-2026<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 1

**Form 13F Information Table Entry Total:** 156

**Form 13F Information Table Value Total:** $362159371

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

| No.   | Name                                     | Form 13F File Number   |
|:---|:---|:---|
|  | HighVista Private Capital Management LLC |  |

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 3M CO | COM | 88579Y101 |  | 893165 | 6150 | SH |  | SOLE |  | 6150 | 0 | 0 |
| ABIVAX SA | SPONSORED ADS | 00370M103 |  | 12610833 | 113254 | SH |  | SOLE |  | 113254 | 0 | 0 |
| ALKERMES PLC | SHS | G01767105 |  | 2587963 | 73189 | SH |  | SOLE |  | 73189 | 0 | 0 |
| ALPHABET INC | CAP STK CL C | 02079K107 |  | 1571132 | 5477 | SH |  | SOLE |  | 5477 | 0 | 0 |
| ALUMIS INC | COM | 022307102 |  | 2487826 | 112929 | SH |  | SOLE |  | 112929 | 0 | 0 |
| AMAZON COM INC | COM | 023135106 |  | 4664623 | 22397 | SH |  | SOLE |  | 22397 | 0 | 0 |
| AMPHENOL CORP | CL A | 032095101 |  | 1235829 | 9781 | SH |  | SOLE |  | 9781 | 0 | 0 |
| AMRIZE LTD | SHS | H2927K103 |  | 956149 | 17068 | SH |  | SOLE |  | 17068 | 0 | 0 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 |  | 4893981 | 352085 | SH |  | SOLE |  | 352085 | 0 | 0 |
| API GROUP CORP | COM STK | 00187Y100 |  | 1080182 | 26658 | SH |  | SOLE |  | 26658 | 0 | 0 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 |  | 3010003 | 35761 | SH |  | SOLE |  | 35761 | 0 | 0 |
| ARGAN INC | COM | 04010E109 |  | 1032656 | 1896 | SH |  | SOLE |  | 1896 | 0 | 0 |
| ARGENX SE | SPONSORED ADR | 04016X101 |  | 3591370 | 4918 | SH |  | SOLE |  | 4918 | 0 | 0 |
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 |  | 1322288 | 5781 | SH |  | SOLE |  | 5781 | 0 | 0 |
| ASSEMBLY BIOSCIENCES INC | COM NEW | 045396207 |  | 2073896 | 74735 | SH |  | SOLE |  | 74735 | 0 | 0 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 |  | 875226 | 58622 | SH |  | SOLE |  | 58622 | 0 | 0 |
| AVANTOR INC | COM | 05352A100 |  | 1462160 | 186500 | SH |  | SOLE |  | 186500 | 0 | 0 |
| AXSOME THERAPEUTICS INC. | COM | 05464T104 |  | 3454262 | 20437 | SH |  | SOLE |  | 20437 | 0 | 0 |
| BANCO BRADESCO S A | SP ADR PFD NEW | 059460303 |  | 760164 | 208264 | SH |  | SOLE |  | 208264 | 0 | 0 |
| BELITE BIO INC | SPONSORED ADS | 07782B104 |  | 1280781 | 8033 | SH |  | SOLE |  | 8033 | 0 | 0 |
| BOOKING HOLDINGS INC | COM | 09857L108 |  | 1191521 | 283 | SH |  | SOLE |  | 283 | 0 | 0 |
| BRIDGEBIO ONCOLOGY THERAPEUT | COM NEW | 107924102 |  | 699774 | 78187 | SH |  | SOLE |  | 78187 | 0 | 0 |
| BRIDGEBIO PHARMA INC | COM | 10806X102 |  | 3680325 | 49560 | SH |  | SOLE |  | 49560 | 0 | 0 |
| BROADCOM INC | COM | 11135F101 |  | 1732946 | 5599 | SH |  | SOLE |  | 5599 | 0 | 0 |
| CELCUITY INC | COM | 15102K100 |  | 1495805 | 13105 | SH |  | SOLE |  | 13105 | 0 | 0 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 |  | 2835673 | 89397 | SH |  | SOLE |  | 89397 | 0 | 0 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 |  | 236890 | 5964 | SH |  | SOLE |  | 5964 | 0 | 0 |
| CG ONCOLOGY INC | COM | 156944100 |  | 1347779 | 19914 | SH |  | SOLE |  | 19914 | 0 | 0 |
| CIENA CORP | COM NEW | 171779309 |  | 2051796 | 5285 | SH |  | SOLE |  | 5285 | 0 | 0 |
| CLEAN HARBORS INC | COM | 184496107 |  | 1589344 | 5543 | SH |  | SOLE |  | 5543 | 0 | 0 |
| CLEVELAND-CLIFFS INC NEW | COM | 185899101 |  | 865905 | 102474 | SH |  | SOLE |  | 102474 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 7584493 | 197051 | SH |  | SOLE |  | 197051 | 0 | 0 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 |  | 2014911 | 364360 | SH |  | SOLE |  | 364360 | 0 | 0 |
| CONSTELLATION ENERGY CORP | COM | 21037T109 |  | 1606247 | 5752 | SH |  | SOLE |  | 5752 | 0 | 0 |
| CORE SCIENTIFIC INC NEW | COM | 21874A106 |  | 1547044 | 103412 | SH |  | SOLE |  | 103412 | 0 | 0 |
| CORPORACION AMER ARPTS S A | COM | L1995B107 |  | 752251 | 29745 | SH |  | SOLE |  | 29745 | 0 | 0 |
| COUPANG INC | CL A | 22266T109 |  | 869160 | 46036 | SH |  | SOLE |  | 46036 | 0 | 0 |
| CYTOKINETICS INC | COM NEW | 23282W605 |  | 3865160 | 58643 | SH |  | SOLE |  | 58643 | 0 | 0 |
| CYTOMX THERAPEUTICS INC. | COM | 23284F105 |  | 1353868 | 288057 | SH |  | SOLE |  | 288057 | 0 | 0 |
| DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 |  | 3512679 | 185856 | SH |  | SOLE |  | 185856 | 0 | 0 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 |  | 2986461 | 35587 | SH |  | SOLE |  | 35587 | 0 | 0 |
| DOORDASH INC | CL A | 25809K105 |  | 1007507 | 6710 | SH |  | SOLE |  | 6710 | 0 | 0 |
| DYNE THERAPEUTICS INC | COM | 26818M108 |  | 3316503 | 182929 | SH |  | SOLE |  | 182929 | 0 | 0 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 |  | 2895827 | 91931 | SH |  | SOLE |  | 91931 | 0 | 0 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 |  | 2865598 | 73102 | SH |  | SOLE |  | 73102 | 0 | 0 |
| ENTERGY CORP NEW | COM | 29364G103 |  | 1520006 | 13528 | SH |  | SOLE |  | 13528 | 0 | 0 |
| EQT CORP | COM | 26884L109 |  | 1163976 | 18290 | SH |  | SOLE |  | 18290 | 0 | 0 |
| ERASCA INC | COM | 29479A108 |  | 2929696 | 181069 | SH |  | SOLE |  | 181069 | 0 | 0 |
| EVERPURE INC | CL A | 74624M102 |  | 827091 | 14009 | SH |  | SOLE |  | 14009 | 0 | 0 |
| EYEPOINT INC | COM NEW | 30233G209 |  | 2359347 | 183037 | SH |  | SOLE |  | 183037 | 0 | 0 |
| FERGUSON ENTERPRISES INC | COMMON STOCK NEW | 31488V107 |  | 1090024 | 4673 | SH |  | SOLE |  | 4673 | 0 | 0 |
| FLOWSERVE CORP | COM | 34354P105 |  | 1834663 | 24958 | SH |  | SOLE |  | 24958 | 0 | 0 |
| FULL TRUCK ALLIANCE CO LTD | SPONSORED ADS | 35969L108 |  | 640685 | 77191 | SH |  | SOLE |  | 77191 | 0 | 0 |
| GE VERNOVA INC | COM | 36828A101 |  | 1063192 | 1218 | SH |  | SOLE |  | 1218 | 0 | 0 |
| GH RESEARCH PLC | ORDINARY SHARES | G3855L106 |  | 2997761 | 213212 | SH |  | SOLE |  | 213212 | 0 | 0 |
| GUARDANT HEALTH INC | COM | 40131M109 |  | 2157486 | 23357 | SH |  | SOLE |  | 23357 | 0 | 0 |
| HDFC BANK LTD | SPONSORED ADS | 40415F101 |  | 650039 | 26127 | SH |  | SOLE |  | 26127 | 0 | 0 |
| HEWLETT PACKARD ENTERPRISE C | COM | 42824C109 |  | 2142448 | 89981 | SH |  | SOLE |  | 89981 | 0 | 0 |
| ICICI BANK LIMITED | ADR | 45104G104 |  | 722195 | 27884 | SH |  | SOLE |  | 27884 | 0 | 0 |
| IMMUNOCORE HLDGS PLC | ADS | 45258D105 |  | 1769715 | 58697 | SH |  | SOLE |  | 58697 | 0 | 0 |
| IMMUNOVANT INC | COM | 45258J102 |  | 5592453 | 225139 | SH |  | SOLE |  | 225139 | 0 | 0 |
| INSMED INC | COM PAR $.01 | 457669307 |  | 3976152 | 24316 | SH |  | SOLE |  | 24316 | 0 | 0 |
| INTUIT | COM | 461202103 |  | 1298437 | 3003 | SH |  | SOLE |  | 3003 | 0 | 0 |
| INVENTIVA SA | ADS | 46124U107 |  | 3416946 | 615666 | SH |  | SOLE |  | 615666 | 0 | 0 |
| INVESCO DB COMMDY INDX TRCK | UNIT | 46138B103 |  | 30607040 | 1057238 | SH |  | SOLE |  | 1057238 | 0 | 0 |
| JAMES HARDIE INDS PLC | ORD SHS | G4253H101 |  | 1242426 | 65598 | SH |  | SOLE |  | 65598 | 0 | 0 |
| JANUX THERAPEUTICS INC | COM | 47103J105 |  | 686424 | 49383 | SH |  | SOLE |  | 49383 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 |  | 2048924 | 10838 | SH |  | SOLE |  | 10838 | 0 | 0 |
| JD.COM INC | SPON ADS CL A | 47215P106 |  | 398101 | 13463 | SH |  | SOLE |  | 13463 | 0 | 0 |
| KANZHUN LIMITED | SPONSORED ADS | 48553T106 |  | 285180 | 21298 | SH |  | SOLE |  | 21298 | 0 | 0 |
| KBR INC | COM | 48242W106 |  | 1452505 | 39406 | SH |  | SOLE |  | 39406 | 0 | 0 |
| KILROY REALTY CORP | COM | 49427F108 |  | 1184736 | 41997 | SH |  | SOLE |  | 41997 | 0 | 0 |
| KNIGHT-SWIFT TRANSN HLDGS IN | CL A | 499049104 |  | 1318582 | 22900 | SH |  | SOLE |  | 22900 | 0 | 0 |
| KODIAK SCIENCES INC | COM | 50015M109 |  | 1660851 | 43569 | SH |  | SOLE |  | 43569 | 0 | 0 |
| KRYSTAL BIOTECH INC | COM | 501147102 |  | 471175 | 1824 | SH |  | SOLE |  | 1824 | 0 | 0 |
| KYMERA THERAPEUTICS INC | COM | 501575104 |  | 315253 | 3785 | SH |  | SOLE |  | 3785 | 0 | 0 |
| LB PHARMACEUTICALS INC | COM SHS | 50180M108 |  | 4280853 | 173595 | SH |  | SOLE |  | 173595 | 0 | 0 |
| LIQUIDIA CORPORATION | COM NEW | 53635D202 |  | 3764338 | 99744 | SH |  | SOLE |  | 99744 | 0 | 0 |
| LUMENTUM HLDGS INC | COM | 55024U109 |  | 2190503 | 3117 | SH |  | SOLE |  | 3117 | 0 | 0 |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 |  | 1359975 | 2598 | SH |  | SOLE |  | 2598 | 0 | 0 |
| MASTEC INC | COM | 576323109 |  | 1166951 | 3627 | SH |  | SOLE |  | 3627 | 0 | 0 |
| MASTERCARD INCORPORATED | CL A | 57636Q104 |  | 1461006 | 2924 | SH |  | SOLE |  | 2924 | 0 | 0 |
| MAZE THERAPEUTICS INC | COM | 578784100 |  | 2980523 | 99850 | SH |  | SOLE |  | 99850 | 0 | 0 |
| MBX BIOSCIENCES INC | COM | 55287L101 |  | 342439 | 11472 | SH |  | SOLE |  | 11472 | 0 | 0 |
| MERCADOLIBRE INC | COM | 58733R102 |  | 752124 | 435 | SH |  | SOLE |  | 435 | 0 | 0 |
| META PLATFORMS INC | CL A | 30303M102 |  | 996651 | 1742 | SH |  | SOLE |  | 1742 | 0 | 0 |
| MICRON TECHNOLOGY INC | COM | 595112103 |  | 1283792 | 3800 | SH |  | SOLE |  | 3800 | 0 | 0 |
| MICROSOFT CORP | COM | 594918104 |  | 2390188 | 6457 | SH |  | SOLE |  | 6457 | 0 | 0 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 |  | 1267216 | 46778 | SH |  | SOLE |  | 46778 | 0 | 0 |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 |  | 1437710 | 15563 | SH |  | SOLE |  | 15563 | 0 | 0 |
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 |  | 3615321 | 193955 | SH |  | SOLE |  | 193955 | 0 | 0 |
| NCR ATLEOS CORPORATION | COM SHS | 63001N106 |  | 1747558 | 40100 | SH |  | SOLE |  | 40100 | 0 | 0 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 |  | 1047232 | 14555 | SH |  | SOLE |  | 14555 | 0 | 0 |
| NEW ORIENTAL ED  TECHNOLOGY | SPON ADR | 647581206 |  | 697512 | 12317 | SH |  | SOLE |  | 12317 | 0 | 0 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 |  | 642344 | 20067 | SH |  | SOLE |  | 20067 | 0 | 0 |
| NEXTERA ENERGY INC | COM | 65339F101 |  | 1029575 | 11085 | SH |  | SOLE |  | 11085 | 0 | 0 |
| NOKIA CORP | SPONSORED ADR | 654902204 |  | 569425 | 70824 | SH |  | SOLE |  | 70824 | 0 | 0 |
| NU HLDGS LTD | ORD SHS CL A | G6683N103 |  | 712321 | 49570 | SH |  | SOLE |  | 49570 | 0 | 0 |
| NURIX THERAPEUTICS INC | COM | 67080M103 |  | 3511464 | 226546 | SH |  | SOLE |  | 226546 | 0 | 0 |
| NUVALENT INC | COM | 670703107 |  | 5798874 | 56602 | SH |  | SOLE |  | 56602 | 0 | 0 |
| NVIDIA CORPORATION | COM | 67066G104 |  | 3910048 | 22420 | SH |  | SOLE |  | 22420 | 0 | 0 |
| OCULAR THERAPEUTIX INC | COM | 67576A100 |  | 3740123 | 441573 | SH |  | SOLE |  | 441573 | 0 | 0 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 |  | 1753431 | 117601 | SH |  | SOLE |  | 117601 | 0 | 0 |
| ON SEMICONDUCTOR CORP | COM | 682189105 |  | 1733760 | 28000 | SH |  | SOLE |  | 28000 | 0 | 0 |
| ORUKA THERAPEUTICS INC | COM | 687604108 |  | 3870585 | 78911 | SH |  | SOLE |  | 78911 | 0 | 0 |
| PALISADE BIO INC | COM | 696389402 |  | 3533820 | 2019326 | SH |  | SOLE |  | 2019326 | 0 | 0 |
| PALVELLA THERAPEUTICS INC NE | COM | 697947109 |  | 735809 | 5903 | SH |  | SOLE |  | 5903 | 0 | 0 |
| PDD HOLDINGS INC | SPONSORED ADS | 722304102 |  | 705042 | 6900 | SH |  | SOLE |  | 6900 | 0 | 0 |
| PENNYMAC FINL SVCS INC NEW | COM | 70932M107 |  | 638544 | 7306 | SH |  | SOLE |  | 7306 | 0 | 0 |
| PETROLEO BRASILEIRO S A | SP ADR NON VTG | 71654V101 |  | 1113750 | 59400 | SH |  | SOLE |  | 59400 | 0 | 0 |
| PHARVARIS N V | COM | N69605108 |  | 2764715 | 97866 | SH |  | SOLE |  | 97866 | 0 | 0 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 |  | 8481008 | 26323 | SH |  | SOLE |  | 26323 | 0 | 0 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 |  | 3568001 | 33852 | SH |  | SOLE |  | 33852 | 0 | 0 |
| PTC INC | COM | 69370C100 |  | 1064970 | 7474 | SH |  | SOLE |  | 7474 | 0 | 0 |
| QXO INC | COM NEW | 82846H405 |  | 511134 | 26320 | SH |  | SOLE |  | 26320 | 0 | 0 |
| RBC BEARINGS INC | COM | 75524B104 |  | 1446328 | 2663 | SH |  | SOLE |  | 2663 | 0 | 0 |
| REDDIT INC | CL A | 75734B100 |  | 929085 | 6900 | SH |  | SOLE |  | 6900 | 0 | 0 |
| RELAY THERAPEUTICS INC | COM | 75943R102 |  | 4197716 | 421881 | SH |  | SOLE |  | 421881 | 0 | 0 |
| REVOLUTION MEDICINES INC | COM | 76155X100 |  | 6740301 | 69309 | SH |  | SOLE |  | 69309 | 0 | 0 |
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 |  | 1460748 | 16796 | SH |  | SOLE |  | 16796 | 0 | 0 |
| RLX TECHNOLOGY INC | SPONSORED ADS | 74969N103 |  | 685740 | 311700 | SH |  | SOLE |  | 311700 | 0 | 0 |
| ROCKET COS INC | COM CL A | 77311W101 |  | 1317128 | 92430 | SH |  | SOLE |  | 92430 | 0 | 0 |
| RXO INC | COMMON STOCK | 74982T103 |  | 629216 | 43038 | SH |  | SOLE |  | 43038 | 0 | 0 |
| SALESFORCE INC | COM | 79466L302 |  | 1551787 | 8313 | SH |  | SOLE |  | 8313 | 0 | 0 |
| SAVARA INC | COM | 805111101 |  | 1370455 | 250999 | SH |  | SOLE |  | 250999 | 0 | 0 |
| SEA LTD | SPONSORD ADS | 81141R100 |  | 616935 | 7450 | SH |  | SOLE |  | 7450 | 0 | 0 |
| SEAGATE TECHNOLOGY HLDNGS PL | ORD SHS | G7997R103 |  | 1136104 | 2900 | SH |  | SOLE |  | 2900 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 |  | 5531800 | 165227 | SH |  | SOLE |  | 165227 | 0 | 0 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 |  | 7377556 | 146264 | SH |  | SOLE |  | 146264 | 0 | 0 |
| STOKE THERAPEUTICS INC | COM | 86150R107 |  | 2038809 | 62617 | SH |  | SOLE |  | 62617 | 0 | 0 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 |  | 5972414 | 123909 | SH |  | SOLE |  | 123909 | 0 | 0 |
| TALEN ENERGY CORP | COM | 87422Q109 |  | 995359 | 3118 | SH |  | SOLE |  | 3118 | 0 | 0 |
| TANGO THERAPEUTICS INC | COM | 87583X109 |  | 2179717 | 104193 | SH |  | SOLE |  | 104193 | 0 | 0 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 |  | 3680349 | 52464 | SH |  | SOLE |  | 52464 | 0 | 0 |
| TERNS PHARMACEUTICALS INC | COM | 880881107 |  | 6026265 | 114307 | SH |  | SOLE |  | 114307 | 0 | 0 |
| TRANSDIGM GROUP INC | COM | 893641100 |  | 1327009 | 1145 | SH |  | SOLE |  | 1145 | 0 | 0 |
| TRAVERE THERAPEUTICS INC | COM | 89422G107 |  | 1079216 | 36325 | SH |  | SOLE |  | 36325 | 0 | 0 |
| TREVI THERAPEUTICS INC | COM | 89532M101 |  | 638553 | 53525 | SH |  | SOLE |  | 53525 | 0 | 0 |
| TRIP COM GROUP LTD | ADS | 89677Q107 |  | 273049 | 5484 | SH |  | SOLE |  | 5484 | 0 | 0 |
| TYRA BIOSCIENCES INC | COM | 90240B106 |  | 5028943 | 131304 | SH |  | SOLE |  | 131304 | 0 | 0 |
| UNION PAC CORP | COM | 907818108 |  | 887504 | 3658 | SH |  | SOLE |  | 3658 | 0 | 0 |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 |  | 897771 | 1514 | SH |  | SOLE |  | 1514 | 0 | 0 |
| UNITY SOFTWARE INC | COM | 91332U101 |  | 1377020 | 62763 | SH |  | SOLE |  | 62763 | 0 | 0 |
| UROGEN PHARMA LTD | COM | M96088105 |  | 476650 | 26510 | SH |  | SOLE |  | 26510 | 0 | 0 |
| VAXCYTE INC | COM | 92243G108 |  | 7243237 | 124647 | SH |  | SOLE |  | 124647 | 0 | 0 |
| VERA THERAPEUTICS INC | CL A | 92337R101 |  | 2785566 | 69241 | SH |  | SOLE |  | 69241 | 0 | 0 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 |  | 2625519 | 134229 | SH |  | SOLE |  | 134229 | 0 | 0 |
| VISA INC | COM CL A | 92826C839 |  | 2158295 | 7141 | SH |  | SOLE |  | 7141 | 0 | 0 |
| WESTERN DIGITAL CORP | COM | 958102105 |  | 1109009 | 4100 | SH |  | SOLE |  | 4100 | 0 | 0 |
| WORKDAY INC | CL A | 98138H101 |  | 1076517 | 8286 | SH |  | SOLE |  | 8286 | 0 | 0 |
| XCEL ENERGY INC | COM | 98389B100 |  | 997608 | 12558 | SH |  | SOLE |  | 12558 | 0 | 0 |
| XENCOR INC | COM | 98401F105 |  | 639723 | 53045 | SH |  | SOLE |  | 53045 | 0 | 0 |
| XENON PHARMACEUTICALS INC | COM | 98420N105 |  | 2852257 | 49050 | SH |  | SOLE |  | 49050 | 0 | 0 |
| XOMA ROYALTY CORPORATION | COM NEW | 98419J206 |  | 1468555 | 46814 | SH |  | SOLE |  | 46814 | 0 | 0 |
| XPO INC | COM | 983793100 |  | 1735970 | 8923 | SH |  | SOLE |  | 8923 | 0 | 0 |
| ZYMEWORKS INC | COM | 98985Y108 |  | 853488 | 34085 | SH |  | SOLE |  | 34085 | 0 | 0 |

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