# EDGAR Filing Document

**Accession Number:** 0001682639
**File Stem:** 0001104659-25-077575
**Filing Date:** 2025-8
**Character Count:** 19404
**Document Hash:** 818c89d1967a7546daebc89018edc40e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-077575.hdr.sgml**: 20250813

**ACCESSION NUMBER**: 0001104659-25-077575

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 14

**CONFORMED PERIOD OF REPORT**: 20250813

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20250813

**DATE AS OF CHANGE**: 20250813

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** HYPERION DEFI, INC.
- **CENTRAL INDEX KEY:** 0001682639
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 471178401
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38365
- **FILM NUMBER:** 251211826

**BUSINESS ADDRESS:**
- **STREET 1:** 23461 SOUTH POINTE DRIVE,
- **STREET 2:** SUITE 390
- **CITY:** LAGUNA HILLS
- **STATE:** CA
- **ZIP:** 92653
- **BUSINESS PHONE:** 833-393-6684

**MAIL ADDRESS:**
- **STREET 1:** 23461 SOUTH POINTE DRIVE,
- **STREET 2:** SUITE 390
- **CITY:** LAGUNA HILLS
- **STATE:** CA
- **ZIP:** 92653

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** EYENOVIA, INC.
- **DATE OF NAME CHANGE:** 20160818

?xml version='1.0' encoding='ASCII'?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d)**

**of the Securities Exchange Act of 1934**

**Date of Report (Date of earliest event reported): August 13, 2025**

**HYPERION DEFI, INC.**

**(Exact Name of Registrant as Specified in its Charter)**

---

| | | |
|:---|:---|:---|
| **Delaware** | **001-38365** | **47-1178401** |
| **(State or other jurisdiction <br> of incorporation)** | **(Commission<br> File Number)** | **(IRS Employer<br> Identification No.)** |

---

23461 South Pointe Drive, Suite 390

Laguna Hills, CA 92653

**(Address of Principal Executive Offices, and Zip Code)**

(833) 393-6684

**Registrant's Telephone Number, Including Area Code**

**Eyenovia, Inc.**

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

◻ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

◻ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

◻ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

◻ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| **(Title of each class)** | **(Trading <br> Symbol)** | **(Name of each exchange <br> on which registered)** |
| **Common stock, par value $0.0001 per share** | **HYPD** | **The Nasdaq Stock Market<br> (Nasdaq Capital Market)** |

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).

Emerging growth company ◻

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ◻

**Item 2.02. Results of Operations and Financial Condition.**

On August 13, 2025, Hyperion DeFi, Inc. (the "Company") issued a press release announcing its financial results for the fiscal quarter ended June 30, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

The information contained in this Item 2.02, including Exhibit 99.1, is being "furnished" and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liability of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended (the "Securities Act"). The information contained in this Item 2.02, including Exhibit 99.1, shall not be incorporated by reference into any registration statement or other document pursuant to the Securities Act or into any filing or other document pursuant to the Exchange Act, except as otherwise expressly stated in any such filing.

**Item 9.01 Financial Statements and Exhibits.**

(d) <u>Exhibits</u>

---

| | |
|:---|:---|
| **Exhibit Number** | **Description** |
| [99.1](tm2523360d1_ex99-1.htm) | [Press Release, dated August 13, 2025.](tm2523360d1_ex99-1.htm) |
| 104 | Cover Page Interactive Data File (embedded within the inline XBRL document). |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  | **HYPERION DEFI, INC.** | **HYPERION DEFI, INC.** |
| Dated: August 13, 2025 | By: | */s/ Michael Rowe* |
|  |  | Michael Rowe |
|  |  | Chief Executive Officer |

---

## Exhibit 99.1

**Exhibit 99.1**

![](tm2523360d1_ex99-1img001.jpg)

**Hyperion DeFi Provides Corporate Update and Reports Second Quarter 2025 Financial Results**

*Successfully establishes cryptocurrency treasury reserve focused on the HYPE token and becomes the first<br> publicly listed U.S. company to implement DeFi strategies on Hyperliquid blockchain*

*Accumulates more than 1.5 million HYPE to date and establishes co-branded validator with Kinetiq*

*Reiterates FDA registration of the Optejet User Filled Device (UFD) remains on track for September 2025*

LAGUNA HILLS, CA—August 13, 2025—Hyperion DeFi, Inc. (NASDAQ: HYPD), the first publicly-listed U.S. company to implement DeFi strategies on its treasury of HYPE, the native token of the Hyperliquid protocol, and a pioneer in ophthalmic digital technologies, today provided a corporate update and announced financial results for the second quarter ended June 30<sup>th</sup>, 2025.

**Second Quarter 2025 and Recent Achievements:**

&nbsp;&nbsp;&nbsp;&nbsp;· Closed a private placement financing of $50 million and successfully established a cryptocurrency treasury
reserve focused on the HYPE token, acquiring more than 1.5 million HYPE to date.

&nbsp;&nbsp;&nbsp;&nbsp;· Appointed cryptocurrency executive Hyunsu Jung as Chief Investment Officer and Board member.

&nbsp;&nbsp;&nbsp;&nbsp;· Announced a co-branded validator with Kinetiq, a leading liquid staking protocol built natively for the
Hyperliquid ecosystem.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o The validator marks a significant step in Hyperion's onchain engagement strategy, enabling the Company
to earn yield on its more than 1.5 million HYPE while contributing directly to Hyperliquid blockchain's stability and security.

&nbsp;&nbsp;&nbsp;&nbsp;· Implemented a corporate rebranding and name change from Eyenovia, Inc. to Hyperion DeFi, Inc.

&nbsp;&nbsp;&nbsp;&nbsp;· Hosted a successful corporate update webinar to discuss the Company's transformation from a digital ophthalmic
technology company into Hyperion DeFi.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;o The event offered insight into how Hyperion DeFi is using blockchain-native assets like HYPE to build
scalable, yield-generating products and support the growth of the Hyperliquid ecosystem.

Michael Rowe, Chief Executive Officer of Hyperion DeFi, stated, "The transformation that we have undergone over the past two months has been nothing short of remarkable, and I could not be more excited to be part of a pioneering organization that is leading the way in leveraging the accelerating adoption of digital currencies to create long-term value for shareholders. Hyperion DeFi blends the benefits of a regulated public company with opportunities only available through decentralized finance, and our focus on HYPE and the Hyperliquid ecosystem truly sets us apart as more and more companies adopt various digital treasury asset strategies."

"At the same time, we continue to work tirelessly to complete the remaining development steps in support of FDA registration of the Optejet User Filled Device, which we anticipate next month. We are pleased with the level of interest we are seeing from potential development partners and view the Optejet UFD as an additional source of value."

![](tm2523360d1_ex99-1img001.jpg)

**Second Quarter 2025 Financial Review**

For the second quarter of 2025, net loss attributable to common stockholders was $8.8 million, or $2.50 per share. This compares to a net loss of $11.1 million, or $16.65 per share, for the second quarter of 2024.

Research and development expenses for the second quarter of 2025 totaled $0.7 million, a decrease of $3.9 million, or 85%, compared to $4.6 million recorded for the second quarter of 2024. The decrease was driven primarily by a reduction in headcount in the fourth quarter of 2024 after the termination of the Company's CHAPERONE study in November 2024.

General and administrative expenses for the second quarter of 2025 totaled $7.7 million, an increase of $3.9 million, or 104%, compared to $3.8 million recorded for the second quarter of 2024. The increase was due to a one-time non-cash stock-based compensation inducement grant given to a newly hired executive, as well as higher professional fees as a result of our assessment of strategic options earlier this year concluding with our $50 million financing and establishment of the treasury strategy in June. These costs were offset by decreases in costs resulting from initiatives that we implemented beginning late last year with the termination of the CHAPERONE study and commercial operations in November 2024.

As of June 30, 2025, the Company's unrestricted cash and cash equivalents were $7.5 million, as compared to $2.1 million in unrestricted and restricted cash as of December 31, 2024.

**About Hyperion DeFi, Inc.**

Hyperion DeFi, Inc. is the first U.S. publicly listed company building a long-term strategic treasury of Hyperliquid's native token, HYPE. The Company is focused on providing its shareholders with simplified access to the Hyperliquid ecosystem, one of the fastest growing, highest revenue-generating blockchains in the world. Shareholders benefit from a gradually compounding exposure to HYPE, both from its native staking yield and additional revenues generated from its unique on-chain utility.

Hyperion DeFi is also developing its proprietary Optejet User Filled Device (UFD) that is designed to work with a variety of topical ophthalmic liquids, including artificial tears and lens rewetting products. The Optejet is especially useful in chronic front-of-the-eye diseases due to its ease of use, enhanced safety and tolerability, and potential for superior compliance versus standard eye drops. Together, these benefits may result in higher treatment compliance and better outcomes for patients and providers.

For more information, please visit Hyperiondefi.com.

**Forward Looking Statements**

Except for historical information, all the statements, expectations and assumptions contained in this press release are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements, our future activities or other future events or conditions, including the estimated market opportunities for our platform technology, the viability of, and risks associated with, our cryptocurrency treasury strategy, the clinical trials that may be necessary in connection with the clearance of the Optejet UFD, and the timing for sales growth of our approved products. These statements are based on current expectations, estimates and projections about our business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Therefore, actual outcomes and results may, and in some cases are likely to, differ materially from what is expressed or forecasted in the forward-looking statements due to numerous factors discussed from time to time in documents which we file with the U.S. Securities and Exchange Commission.

![](tm2523360d1_ex99-1img001.jpg)

In addition, such statements could be affected by risks and uncertainties related to, among other things: risks of our clinical trials, including, but not limited to, the potential advantages of our products, and platform technology; the rate and degree of market acceptance and clinical utility of our products; our estimates regarding the potential market opportunity for our products; reliance on third parties to develop and commercialize our products; the ability of us and our partners to timely develop, implement and maintain manufacturing, commercialization and marketing capabilities and strategies for our products; intellectual property risks; changes in legal, regulatory, legislative and geopolitical environments in the markets in which we operate and the impact of these changes on our ability to obtain regulatory approval for our products and product candidates; our competitive position; our ability to raise additional funds to maintain our business operations and to make payments on our debt obligations as and when necessary; and the risks of our cryptocurrency strategy as detailed in our Current Report on Form 8-K filed on June 27, 2025.

Any forward-looking statements speak only as of the date on which they are made, and except as may be required under applicable securities laws, Hyperion DeFi does not undertake any obligation to update any forward-looking statements.

**Hyperion DeFi Investor Contact:**<br> Eric Ribner<br> LifeSci Advisors, LLC<br> <u>eric@lifesciadvisors.com</u><br> (646) 751-4363

![](tm2523360d1_ex99-1img001.jpg)

**Hyperion DeFi, Inc.**

**Condensed Balance Sheets**

**(unaudited)**

---

| | | |
|:---|:---|:---|
|  | **June 30,**<br>**2025** | **December 31,**<br>**2024** |
|  | **(unaudited)** |  |
| **Assets** |  |  |
| Current Assets |  |  |
| &nbsp;&nbsp;&nbsp;Cash and cash equivalents | $7532291 | $2121463 |
| &nbsp;&nbsp;&nbsp;Deposit to be refunded | 888000 |  |
| &nbsp;&nbsp;&nbsp;Prepaid expenses and other current assets | 967006 | 645736 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Current Assets | 9387297 | 2767199 |
| HYPE digital tokens | 45500000 |  |
| Property and equipment, net | 22959 |  |
| Security deposits, non-current | 182200 | 182200 |
| Operating lease right-of-use asset | 567180 | 718360 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Assets | $55659636 | $3667759 |
| **Liabilities and Stockholders' Equity (Deficiency)** |  |  |
| Current Liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;Accounts payable | $901594 | $1954681 |
| &nbsp;&nbsp;&nbsp;Accrued inducement grant | 5190000 |  |
| &nbsp;&nbsp;&nbsp;Accrued former licensor obligations | 2245087 | 2245087 |
| &nbsp;&nbsp;&nbsp;Accrued expenses and other current liabilities | 1496804 | 1322674 |
| &nbsp;&nbsp;&nbsp;Operating lease liabilities - current portion | 477609 | 575163 |
| &nbsp;&nbsp;&nbsp;Notes payable - current portion, net of debt discount of $0 and $527,870 as of June 30, 2025 and December 31, 2024, respectively |  | 5212532 |
| &nbsp;&nbsp;&nbsp;Convertible notes payable - current portion, net of debt discount of $0 and $263,930 as of June 30, 2025 and December 31, 2024, respectively |  | 4736070 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Current Liabilities | 10311094 | 16046207 |
| &nbsp;&nbsp;&nbsp;Notes payable - non-current portion, net of debt discount of $654,151 and $0 as of June 30, 2025 and December 31, 2024, respectively | 7516735 |  |
| &nbsp;&nbsp;&nbsp;Operating lease liabilities - non-current portion | 473241 | 717504 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Liabilities | 18301070 | 16763711 |
| Stockholders' Equity (Deficiency): |  |  |
| &nbsp;&nbsp;&nbsp;Preferred stock, $0.0001 par value, 6,000,000 shares authorized; Series A Non-Voting Convertible Preferred Stock, 5,435,898 shares designated, and 5,435,897 and 0 shares issued and outstanding as of June 30, 2025 and December 31, 2024, respectively | 544 |  |
| &nbsp;&nbsp;&nbsp;Common stock, $0.0001 par value, 300,000,000 shares authorized; 4,854,827 and 1,506,369 shares issued and outstanding as of June 30, 2025 and December 31, 2024, respectively | 485 | 151 |
| &nbsp;&nbsp;&nbsp;Additional paid-in capital | 244841981 | 182213889 |
| &nbsp;&nbsp;&nbsp;Accumulated deficit | (207484444) | (195309992) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Stockholders' Equity (Deficiency) | 37358566 | (13095952) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Liabilities and Stockholders' Equity (Deficiency) | $55659636 | $3667759 |

---

**Hyperion DeFi, Inc.**

**Condensed Statement of Operations**

**(unaudited)**

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **For the Three Months Ended** | **For the Three Months Ended** | **For the Six Months Ended** | **For the Six Months Ended** |
|  | **June 30,** | **June 30,** | **June 30,** | **June 30,** |
|  | **2025** | **2024** | **2025** | **2024** |
| **Operating Income** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Revenue | $— | 22625 | $14720 | $27618 |
| &nbsp;&nbsp;&nbsp;Cost of revenue |  | (490361) | (48) | (693388) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Gross Profit (Loss) |  | (467736) | 14672 | (665770) |
| **Operating Expenses:** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Research and development | 674578 | 4597173 | 1347621 | 9028774 |
| &nbsp;&nbsp;&nbsp;Selling, general and administrative | 7678704 | 3758835 | 10051026 | 7396024 |
| &nbsp;&nbsp;&nbsp;Reacquisition of license rights |  | 2864600 |  | 4864600 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Operating Expenses | 8353282 | 11220608 | 11398647 | 21289398 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Loss From Operations | (8353282) | (11688344) | (11383975) | (21955168) |
| **Other Income (Expense):** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Other income (expense), net | 168840 | 2980 | 172527 | (94578) |
| &nbsp;&nbsp;&nbsp;Gain on debt extinguishment |  |  | 89623 |  |
| &nbsp;&nbsp;&nbsp;Change in fair value of equity consideration payable |  | 1240800 |  | 1240800 |
| &nbsp;&nbsp;&nbsp;Interest expense | (528410) | (674001) | (1109909) | (1352659) |
| &nbsp;&nbsp;&nbsp;Interest income | 21933 | 64866 | 57282 | 185805 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total Other Income (Expense) | (337637) | 634645 | (790477) | (20632) |
| **Net Loss** | (8690919) | (11053699) | (12174452) | (21975800) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Dividend to preferred stockholders | (97167) |  | (97167) |  |
| **Net Loss Attributable to Common Stockholders** | $(8788086) | $(11053699) | $(12271619) | $(21975800) |
| Net Loss Per Share - Basic and Diluted | $(2.50) | $(16.65) | $(4.29) | $(35.26) |
| Weighted Average Shares Outstanding - Basic and Diluted | 3518906 | 664022 | 2857596 | 623303 |

---