# EDGAR Filing Document

**Accession Number:** 0001039803
**File Stem:** 0000910472-25-001323
**Filing Date:** 2025-9
**Character Count:** 21273
**Document Hash:** 01f88d9f80acea64e1dcc1a97fc4cec5
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000910472-25-001323.hdr.sgml**: 20250926

**ACCESSION NUMBER**: 0000910472-25-001323

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250731

**FILED AS OF DATE**: 20250926

**DATE AS OF CHANGE**: 20250926

**PERIOD START**: 20250731

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ProFunds
- **CENTRAL INDEX KEY:** 0001039803

**ORGANIZATION NAME:**
- **EIN:** 522035197
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-08239
- **FILM NUMBER:** 251346515

**BUSINESS ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814
- **BUSINESS PHONE:** 2404976428

**MAIL ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PROFUNDS
- **DATE OF NAME CHANGE:** 19970521

## Series and Classes Contracts Data

### PHARMACEUTICALS ULTRASECTOR PROFUND (Series ID: S000003093)

| Class ID   | Class Name                                         | Ticker Symbol   |
|:---|:---|:---|
| C000008401 | PHARMACEUTICALS ULTRASECTOR PROFUND INVESTOR CLASS | PHPIX           |
| C000008402 | PHARMACEUTICALS ULTRASECTOR PROFUND SERVICE CLASS  | PHPSX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ProFunds

- **b. Investment Company Act file number:** 811-08239

- **c. CIK number of Registrant:** 0001039803

- **d. LEI of Registrant:** 549300HM4OOUYSE5DP77

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 7272 Wisconsin Avenue

  - **City:** Bethesda

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 20814

  - **Telephone number:** 240-497-6400

**Item A.2. Information about the Series.**

- **a. Name of Series:** PHARMACEUTICALS ULTRASECTOR PROFUND

- **b. EDGAR series identifier (if any):** S000003093

- **c. LEI of Series:** O4X73XQHFKFTUZE9BD44

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-07-31

- **b. Date as of which information is reported:** 2025-07-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $5842404.37

**Total Liabilities:** $3381439.27

**Net Assets:** $2460965.10

**Cash Not Reported:** $1461.36

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000008402 | -3.03%               | -0.49%               | 2.15%                |
| Class ID C000008401 | -2.95%               | -0.41%               | 2.23%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $-16044.96               | $-22176.95                                 |
| Month 2  | $-3458.17                | $1481.19                                   |
| Month 3  | $4168.79                 | $46260.03                                  |

**Designated Index Information**

- **Index Name:** Dow Jones U.S. Select Pharmaceuticals Index

- **Index Identifier:** DJSPHM

### Schedule of Portfolio Investments

| Name                                | Title                                         | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Collegium Pharmaceutical Inc.       | Collegium Pharmaceutical, Inc.                | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |       989 | NS      | $29531.54     | 1.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Wave Life Sciences Ltd.             | WaVe Life Sciences Ltd.                       | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | SG        |      4147 | NS      | $33590.70     | 1.36%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | HSBC SECURITIES (USA), INC.  4.25 , 8/01/2025 | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |    159000 | PA      | $159000.00    | 6.46%             |  |  |  | No            |                  2 | On Loan: No      |
| Tarsus Pharmaceuticals Inc          | Tarsus Pharmaceuticals Inc                    | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1775 | NS      | $68905.50     | 2.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Bristol-Myers Squibb Company        | Bristol-Myers Squibb Co.                      | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |      1458 | NS      | $63145.98     | 2.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Mind Medicine (MindMed) Inc.        | Mind Medicine MindMed Inc                     | CUSIP: 60255C885<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | CA        |      2501 | NS      | $22734.09     | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Ligand Pharmaceuticals Incorporated | Ligand Pharmaceuticals, Inc.                  | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |       312 | NS      | $41052.96     | 1.67%             |  |  |  | No            |                  1 | On Loan: No      |
| Organon & Co                        | Organon & Co.                                 | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |      7253 | NS      | $70354.10     | 2.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings Inc    | Harmony Biosciences Holdings, Inc.            | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1672 | NS      | $58820.96     | 2.39%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | UMB FINANCIAL CORP.  4.09 , 8/01/2025         | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |    116000 | PA      | $116000.00    | 4.71%             |  |  |  | No            |                  2 | On Loan: No      |
| Arvinas Inc                         | Arvinas, Inc.                                 | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2821 | NS      | $20988.24     | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Perrigo Company PLC                 | Perrigo Co. PLC                               | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | IE        |      2671 | NS      | $71235.57     | 2.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc.            | Axsome Therapeutics, Inc.                     | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |       676 | NS      | $68532.88     | 2.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc            | Enliven Therapeutics Inc                      | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       776 | NS      | $14596.56     | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| Innoviva Inc                        | Innoviva, Inc.                                | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |      1934 | NS      | $35140.78     | 1.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Johnson & Johnson                   | Johnson & Johnson                             | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |       471 | NS      | $77592.54     | 3.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacira Biosciences Inc              | Pacira Pharmaceuticals, Inc./DE               | CUSIP: 695127100<br>LEI: 549300P56LERYBDHCF69 | Long             | EC               | CORP              | US        |      2079 | NS      | $43846.11     | 1.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Liquidia Corporation                | Liquidia Corp                                 | CUSIP: 53635D202<br>LEI: 549300O826O5VQJTG707 | Long             | EC               | CORP              | US        |      2238 | NS      | $41828.22     | 1.70%             |  |  |  | No            |                  1 | On Loan: No      |
| Harrow Inc                          | Harrow Health, Inc.                           | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1103 | NS      | $35031.28     | 1.42%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | ROYAL BANK OF CANADA  4.14 , 8/01/2025        | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     39000 | PA      | $39000.00     | 1.58%             |  |  |  | No            |                  2 | On Loan: No      |
| Evolus Inc                          | Evolus Inc                                    | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |      1998 | NS      | $17822.16     | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Zevra Therapeutics Inc              | Zevra Therapeutics Inc                        | CUSIP: 488445206<br>LEI: 254900CU6T74V18Y1W18 | Long             | EC               | CORP              | US        |      1056 | NS      | $11732.16     | 0.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co.                     | Eli Lilly & Co.                               | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |        90 | NS      | $66606.30     | 2.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Amphastar Pharmaceuticals Inc       | Amphastar Pharmaceuticals, Inc.               | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |      1597 | NS      | $33457.15     | 1.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Viatris Inc                         | Viatris, Inc.                                 | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |      8141 | NS      | $71152.34     | 2.89%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | PHPIX_SPSIPH_UBS                              | CUSIP: N/A<br>LEI: N/A                        | Short            | DE               |  | US        |       -22 | OU      | $-12.47       | -0.00%            |  |  |  | No            |                  2 | On Loan: No      |
| Zoetis Inc.                         | Zoetis, Inc.                                  | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |       440 | NS      | $64147.60     | 2.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Merck & Co., Inc                    | Merck & Co., Inc.                             | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |       910 | NS      | $71089.20     | 2.89%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | SOCIETE' GENERALE  4.22 , 8/01/2025           | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |    159000 | PA      | $159000.00    | 6.46%             |  |  |  | No            |                  2 | On Loan: No      |
| Lenz Therapeutics Inc               | LENZ Therapeutics Inc                         | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       539 | NS      | $16046.03     | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc.          | Edgewise Therapeutics, Inc.                   | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2787 | NS      | $39742.62     | 1.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Supernus Pharmaceuticals, Inc       | Supernus Pharmaceuticals, Inc.                | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |      1240 | NS      | $43524.00     | 1.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocular Therapeutix Inc              | OCULAR THERAPEUTIX                            | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |      4126 | NS      | $47779.08     | 1.94%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | PHPIX_SPSIPH_GOLDMAN                          | CUSIP: N/A<br>LEI: N/A                        | Long             | DE               |  | US        |       329 | OU      | $-74064.58    | -3.01%            |  |  |  | No            |                  2 | On Loan: No      |
| Trevi Therapeutics Inc              | Trevi Therapeutics Inc                        | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3378 | NS      | $25014.09     | 1.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CorMedix Inc.                       | CorMedix Inc                                  | CUSIP: 21900C308<br>LEI: 5299006YIA3L0MBW8358 | Long             | EC               | CORP              | US        |      2170 | NS      | $25323.90     | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvation Bio Inc                    | Nuvation Bio, Inc.                            | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8726 | NS      | $20593.36     | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| Amneal Pharmaceuticals Inc          | Amneal Pharmaceuticals, Inc.                  | CUSIP: 03168L105<br>LEI: 549300VV176ZO5WQHZ61 | Long             | EC               | CORP              | US        |      5224 | NS      | $40851.68     | 1.66%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | NATWEST MARKETS PLC  4.22 , 8/01/2025         | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     66000 | PA      | $66000.00     | 2.68%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | CREDIT AGRICOLE CIB NY  4.23 , 8/01/2025      | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     66000 | PA      | $66000.00     | 2.68%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | PHPIX_SPSIPH_UBS                              | CUSIP: N/A<br>LEI: N/A                        | Long             | DE               |  | US        |       188 | OU      | $-47475.36    | -1.93%            |  |  |  | No            |                  2 | On Loan: No      |
| EyePoint Pharmaceuticals Inc.       | EyePoint Pharmaceuticals, Inc.                | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |      1609 | NS      | $15800.38     | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Elanco Animal Health Inc            | Elanco Animal Health, Inc.                    | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |      5123 | NS      | $70082.64     | 2.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Corcept Therapeutics Inc.           | Corcept Therapeutics, Inc.                    | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |      1026 | NS      | $68916.42     | 2.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Royalty Pharma PLC                  | Royalty Pharma PLC                            | CUSIP: G7709Q104<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |      2147 | NS      | $79009.60     | 3.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Prestige Consumer Healthcare Inc    | Prestige Consumer Healthcare, Inc.            | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       859 | NS      | $63523.05     | 2.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc.                         | Pfizer, Inc.                                  | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |      2986 | NS      | $69543.94     | 2.83%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | PHPIX_SPSIPH_GOLDMAN                          | CUSIP: N/A<br>LEI: N/A                        | Short            | DE               |  | US        |      -150 | OU      | $28786.59     | 1.17%             |  |  |  | No            |                  2 | On Loan: No      |
| ANI Pharmaceuticals Inc.            | ANI Pharmaceuticals, Inc.                     | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |       705 | NS      | $44661.75     | 1.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC            | Jazz Pharmaceuticals PLC                      | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | IE        |       662 | NS      | $75885.06     | 3.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc        | Xeris Biopharma Holdings Inc                  | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7968 | NS      | $40557.12     | 1.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Phibro Animal Health Corporation    | Phibro Animal Health Corp.                    | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |       624 | NS      | $16536.00     | 0.67%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-07-31

**Name of Applicant:** Pharmaceuticals UltraSector ProFund

**Signature:** Rebecca Colvin

**Name of Signer:** Rebecca Colvin

**Title:** Treasurer and Principal Financial Officer