# EDGAR Filing Document

**Accession Number:** 0001055951
**File Stem:** 0001438934-25-002680
**Filing Date:** 2025-8
**Character Count:** 142376
**Document Hash:** 40d9198c27fcf99ccade62e42b9de7e0
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001438934-25-002680.hdr.sgml**: 20250829

**ACCESSION NUMBER**: 0001438934-25-002680

**CONFORMED SUBMISSION TYPE**: N-PX

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250829

**EFFECTIVENESS DATE**: 20250829

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ORBIMED ADVISORS LLC
- **CENTRAL INDEX KEY:** 0001055951

**ORGANIZATION NAME:**
- **EIN:** 133976876
- **STATE OF INCORPORATION:** DE

**FILING VALUES:**
- **FORM TYPE:** N-PX
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-06774
- **FILM NUMBER:** 251280544

**BUSINESS ADDRESS:**
- **STREET 1:** 601 LEXINGTON AVENUE
- **STREET 2:** 54TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022
- **BUSINESS PHONE:** (212) 739-6400

**MAIL ADDRESS:**
- **STREET 1:** 601 LEXINGTON AVENUE
- **STREET 2:** 54TH FLOOR
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10022

## FORM N-PX
### ANNUAL REPORT OF PROXY VOTING RECORD

## N-PX: Filer Information

**Filer CIK:** 0001055951

**Date of Report:** 06/30/2025

**Are you a Registered Management Investment Company or an Institutional Manager?:** Institutional Manager

**Is this a LIVE or TEST Filing?:** LIVE

**Is this an electronic copy of an official filing submitted in paper format?:** [ ]

### Submission Contact Information
_Not provided in this filing._

### Notification Information
**Notify via Filing Website only?:** [ ]

## N-PX: Cover Page

**Name of reporting person:** OrbiMed Advisors LLC

**Address:** 601 Lexington Avenue, New York, NY 10022

**Telephone number:** 2127396400

**Name of agent for service:** —

**Agent Address:** —, —, — —

**Reporting Period:** Report for the year ended 06/30/2025

**SEC File Number:** 028-06774

**CRD Number (if any):** —

**Other SEC File Number (if any):** —

**LEI (if any):** —

**Report Type (check only one):**

Institutional Manager.

- [x] Institutional Manager Voting Report

- [ ] Institutional Manager Notice Report

- [ ] Institutional Manager Combination Report

Registered Management Investment Company.

- [ ] Fund Voting Report

- [ ] Fund Notice Report

**Do you wish to provide explanatory information pursuant to Special Instruction B.4?:**

- [x] No

- [ ] Yes

**Additional information:** —

## N-PX: Summary - Included Managers

**Number of Included Institutional Managers:** 1

**Included Institutional Managers:** —

## FORM N-PX PROXY VOTING RECORD

| NAME OF ISSUER                        | CUSIP     | MEETING DATE   | VOTE DESCRIPTION                                                                                                                                                                                                                                                                                                                                                                                                                                                          | VOTE CATEGORY                |   SHARES VOTED |   SHARES ON LOAN | HOW VOTED   |   SHARES VOTED FOR OR AGAINST MANAGEMENT | FOR OR AGAINST MANAGEMENT   | OTHER INFO   |
|:---|:---|:---|:---|:---|---:|---:|:---|---:|:---|:---|
| ADC THERAPEUTICS SA                   | H0036K147 | 06/03/2025     | Approving, on an advisory basis under U.S. law, the compensation paid to our Named Executive Officers: The Board of Directors is proposing that the following proposal: "RESOLVED, that the Company's Shareholders approve, on an advisory basis under U.S. law, the compensation of the Company's Named Executive Officers, as disclosed in "Executive Compensation" and the related compensation tables and narrative disclosure in this proxy statement", be approved. | SECTION 14A SAY-ON-PAY VOTES |        2131612 |                0 | FOR         |                                  2131612 | FOR                         |  |
| AGIOS PHARMACEUTICALS, INC.           | 00847X104 | 06/18/2025     | To vote, on an advisory basis, to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         202905 |                0 | FOR         |                                   202905 | FOR                         |  |
| AKERO THERAPEUTICS, INC               | 00973Y108 | 06/03/2025     | To consider and act upon a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |          88400 |                0 | FOR         |                                    88400 | FOR                         |  |
| ALNYLAM PHARMACEUTICALS, INC.         | 02043Q107 | 05/08/2025     | To approve, in a non-binding advisory vote, the compensation of Alnylam's named executive officers.                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |          27460 |                0 | FOR         |                                    27460 | FOR                         |  |
| AMGEN INC.                            | 031162100 | 05/23/2025     | Advisory vote to approve our executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |          44200 |                0 | FOR         |                                    44200 | FOR                         |  |
| AMICUS THERAPEUTICS, INC.             | 03152W109 | 06/05/2025     | Approval, on an advisory basis, the Company's executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |        1150800 |                0 | FOR         |                                  1150800 | FOR                         |  |
| AMYLYX PHARMACEUTICALS, INC.          | 03237H101 | 06/05/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         348000 |                0 | AGAINST     |                                   348000 | AGAINST                     |  |
| ARGENX SE                             | N0610Q109 | 05/27/2025     | THE 2024 REMUNERATION REPORT                                                                                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |          14183 |                0 | FOR         |                                    14183 | FOR                         |  |
| ARGENX SE                             | 04016X101 | 05/27/2025     | The 2024 remuneration report                                                                                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |          24400 |                0 | FOR         |                                    24400 | FOR                         |  |
| AVIDITY BIOSCIENCES, INC.             | 05370A108 | 06/10/2025     | To consider and vote upon, on an advisory basis, the compensation of our named executive officers as disclosed in this proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         407456 |                0 | AGAINST     |                                   407456 | AGAINST                     |  |
| AXSOME THERAPEUTICS, INC.             | 05464T104 | 06/06/2025     | To approve, by non-binding advisory vote, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |          76600 |                0 | FOR         |                                    76600 | FOR                         |  |
| C4 THERAPEUTICS, INC.                 | 12529R107 | 06/18/2025     | To cast a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |        1751200 |                0 | FOR         |                                  1751200 | FOR                         |  |
| CORBUS PHARMACEUTICALS HOLDINGS, INC. | 21833P301 | 05/15/2025     | Approval, on an advisory basis, of the executive compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |         395300 |                0 | FOR         |                                   395300 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, to approve our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         416757 |                0 | FOR         |                                   416757 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, on the frequency of future advisory votes on our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         416757 |                0 | 1 YEAR      |                                   416757 | FOR                         |  |
| CYTOKINETICS, INCORPORATED            | 23282W605 | 05/14/2025     | To approve, on an advisory basis, the compensation of Cytokinetics, Incorporated's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         170300 |                0 | FOR         |                                   170300 | FOR                         |  |
| DYNE THERAPEUTICS, INC.               | 26818M108 | 05/30/2025     | To vote, on an advisory basis, to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         432420 |                0 | AGAINST     |                                   432420 | AGAINST                     |  |
| DYNE THERAPEUTICS, INC.               | 26818M108 | 05/30/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         432420 |                0 | 1 YEAR      |                                   432420 | FOR                         |  |
| EDGEWISE THERAPEUTICS INC             | 28036F105 | 06/13/2025     | Conduct an advisory vote on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         265625 |                0 | FOR         |                                   265625 | FOR                         |  |
| EDGEWISE THERAPEUTICS INC             | 28036F105 | 06/13/2025     | Conduct an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         265625 |                0 | 1 YEAR      |                                   265625 | FOR                         |  |
| EXACT SCIENCES CORPORATION            | 30063P105 | 06/12/2025     | To approve, on an advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |          72500 |                0 | FOR         |                                    72500 | FOR                         |  |
| FATE THERAPEUTICS, INC.               | 31189P102 | 05/29/2025     | To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers as disclosed in the proxy statement.                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         687000 |                0 | AGAINST     |                                   687000 | AGAINST                     |  |
| FATE THERAPEUTICS, INC.               | 31189P102 | 05/29/2025     | To recommend, on a non-binding advisory basis, the frequency of future non-binding stockholder advisory votes to approve the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         687000 |                0 | 1 YEAR      |                                   687000 | FOR                         |  |
| GILEAD SCIENCES, INC.                 | 375558103 | 05/07/2025     | To approve, on an advisory basis, the compensation of our Named Executive Officers as presented in the Proxy Statement.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         281300 |                0 | FOR         |                                   281300 | FOR                         |  |
| INSMED INCORPORATED                   | 457669307 | 05/15/2025     | An advisory vote on the 2024 compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                                | SECTION 14A SAY-ON-PAY VOTES |          28659 |                0 | FOR         |                                    28659 | FOR                         |  |
| IONIS PHARMACEUTICALS, INC.           | 462222100 | 06/05/2025     | To make an advisory vote on executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         280300 |                0 | FOR         |                                   280300 | FOR                         |  |
| KEZAR LIFE SCIENCES, INC.             | 49372L209 | 06/17/2025     | Advisory vote on the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         192700 |                0 | FOR         |                                   192700 | FOR                         |  |
| KORRO BIO, INC.                       | 500946108 | 06/11/2025     | Non-Binding Advisory Vote to Approve the Compensation of our Named Executive Officers.                                                                                                                                                                                                                                                                                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |          32400 |                0 | FOR         |                                    32400 | FOR                         |  |
| KORRO BIO, INC.                       | 500946108 | 06/11/2025     | Non-Binding Advisory Vote on the Frequency of Future Non-Binding Advisory Votes to Approve the Compensation of our Named Executive Officers                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |          32400 |                0 | 1 YEAR      |                                    32400 | FOR                         |  |
| KRYSTAL BIOTECH, INC.                 | 501147102 | 05/16/2025     | Approval of the compensation of the Company's named executive officers, on a non-binding, advisory basis.                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |          23500 |                0 | FOR         |                                    23500 | FOR                         |  |
| NEUROCRINE BIOSCIENCES, INC.          | 64125C109 | 05/21/2025     | Advisory vote on the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         136300 |                0 | FOR         |                                   136300 | FOR                         |  |
| REPARE THERAPEUTICS INC.              | 760273102 | 06/17/2025     | To approve, on an advisory basis, the compensation of our named executive officers, as disclosed in the accompanying proxy statement.                                                                                                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |          49257 |                0 | FOR         |                                    49257 | FOR                         |  |
| RHYTHM PHARMACEUTICALS, INC.          | 76243J105 | 09/18/2024     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         292700 |                0 | FOR         |                                   292700 | FOR                         |  |
| RHYTHM PHARMACEUTICALS, INC.          | 76243J105 | 06/24/2025     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |          79225 |                0 | AGAINST     |                                    79225 | AGAINST                     |  |
| SCHOLAR ROCK HOLDING CORPORATION      | 80706P103 | 05/22/2025     | To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |         151800 |                0 | FOR         |                                   151800 | FOR                         |  |
| SPRINGWORKS THERAPEUTICS INC          | 85205L107 | 05/14/2025     | Non-binding advisory vote on executive compensation                                                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |          30200 |                0 | FOR         |                                    30200 | FOR                         |  |
| STRUCTURE THERAPEUTICS, INC.          | 86366E106 | 06/23/2025     | TO APPROVE, ON AN ADVISORY BASIS, THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS, AS DISCLOSED IN THE PROXY STATEMENT.                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         250800 |                0 | FOR         |                                   250800 | FOR                         |  |
| STRUCTURE THERAPEUTICS, INC.          | 86366E106 | 06/23/2025     | TO INDICATE, ON AN ADVISORY BASIS, THE PREFERRED FREQUENCY OF SHAREHOLDER ADVISORY VOTES ON THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS.                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         250800 |                0 | 1 YEAR      |                                   250800 | FOR                         |  |
| TARSUS PHARMACEUTICALS, INC.          | 87650L103 | 06/12/2025     | To hold an advisory vote to approve, on a non-binding basis, named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         218000 |                0 | FOR         |                                   218000 | FOR                         |  |
| TARSUS PHARMACEUTICALS, INC.          | 87650L103 | 06/12/2025     | To hold an advisory vote to approve, on a non-binding basis, the frequency with which future stockholder votes on the compensation of our named executive officers will be conducted of one, two or three years.                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         218000 |                0 | 1 YEAR      |                                   218000 | FOR                         |  |
| THE BIOTECH GROWTH TRUST PLC          | G1281H103 | 07/18/2024     | TO APPROVE THE DIRECTORS' REMUNERATION REPORT FOR THE YEAR ENDED 31 MARCH 2024                                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |          75000 |                0 | FOR         |                                    75000 | FOR                         |  |
| TREVI THERAPEUTICS INC                | 89532M101 | 06/11/2025     | Approval, on an advisory basis, of the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |         492000 |                0 | FOR         |                                   492000 | FOR                         |  |
| TREVI THERAPEUTICS INC                | 89532M101 | 06/11/2025     | Approval, on an advisory basis, of the frequency of future advisory votes to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         492000 |                0 | 1 YEAR      |                                   492000 | FOR                         |  |
| VERA THERAPEUTICS, INC.               | 92337R101 | 05/14/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |          41993 |                0 | FOR         |                                    41993 | FOR                         |  |
| VERA THERAPEUTICS, INC.               | 92337R101 | 05/14/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |          41993 |                0 | 1 YEAR      |                                    41993 | FOR                         |  |
| VERTEX PHARMACEUTICALS INCORPORATED   | 92532F100 | 05/14/2025     | Advisory vote to approve named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |          16300 |                0 | FOR         |                                    16300 | FOR                         |  |
| VIR BIOTECHNOLOGY, INC.               | 92764N102 | 05/29/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         911933 |                0 | FOR         |                                   911933 | FOR                         |  |
| XENON PHARMACEUTICALS INC             | 98420N105 | 06/04/2025     | To approve, on an advisory basis, the compensation of the Corporation's named executive officers.                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         319300 |                0 | FOR         |                                   319300 | FOR                         |  |
| ZAI LAB LTD                           | G9887T116 | 06/18/2025     | THAT, ON AN ADVISORY BASIS, THE COMPENSATION OF THE COMPANYS NAMED EXECUTIVE OFFICERS, AS DISCLOSED IN THE PROXY STATEMENT, IS HEREBY APPROVED                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |        1212000 |                0 | FOR         |                                  1212000 | FOR                         |  |
| ADC THERAPEUTICS SA                   | H0036K147 | 06/03/2025     | Approving, on an advisory basis under U.S. law, the compensation paid to our Named Executive Officers: The Board of Directors is proposing that the following proposal: "RESOLVED, that the Company's Shareholders approve, on an advisory basis under U.S. law, the compensation of the Company's Named Executive Officers, as disclosed in "Executive Compensation" and the related compensation tables and narrative disclosure in this proxy statement", be approved. | SECTION 14A SAY-ON-PAY VOTES |        2530638 |                0 | FOR         |                                  2530638 | FOR                         |  |
| ADICET BIO, INC.                      | 007002108 | 06/11/2025     | To ratify, on a non-binding advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        1255985 |                0 | FOR         |                                  1255985 | FOR                         |  |
| AGIOS PHARMACEUTICALS, INC.           | 00847X104 | 06/18/2025     | To vote, on an advisory basis, to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |          68117 |                0 | FOR         |                                    68117 | FOR                         |  |
| AKERO THERAPEUTICS, INC               | 00973Y108 | 06/03/2025     | To consider and act upon a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |          51500 |                0 | FOR         |                                    51500 | FOR                         |  |
| ALNYLAM PHARMACEUTICALS, INC.         | 02043Q107 | 05/08/2025     | To approve, in a non-binding advisory vote, the compensation of Alnylam's named executive officers.                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |          58000 |                0 | FOR         |                                    58000 | FOR                         |  |
| AMICUS THERAPEUTICS, INC.             | 03152W109 | 06/05/2025     | Approval, on an advisory basis, the Company's executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |         542300 |                0 | FOR         |                                   542300 | FOR                         |  |
| APELLIS PHARMACEUTICALS INC.          | 03753U106 | 06/03/2025     | To hold an advisory vote to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                | SECTION 14A SAY-ON-PAY VOTES |         115200 |                0 | FOR         |                                   115200 | FOR                         |  |
| APELLIS PHARMACEUTICALS INC.          | 03753U106 | 06/03/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         115200 |                0 | 1 YEAR      |                                   115200 | FOR                         |  |
| ARGENX SE                             | 04016X101 | 05/27/2025     | The 2024 remuneration report                                                                                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |          30200 |                0 | FOR         |                                    30200 | FOR                         |  |
| AVALO THERAPEUTICS INC                | 05338F306 | 06/17/2025     | To approve, on a nonbinding advisory basis, a "Say-on-Pay" resolution regarding the compensensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         322333 |                0 | FOR         |                                   322333 | FOR                         |  |
| AVIDITY BIOSCIENCES, INC.             | 05370A108 | 06/10/2025     | To consider and vote upon, on an advisory basis, the compensation of our named executive officers as disclosed in this proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         309230 |                0 | AGAINST     |                                   309230 | AGAINST                     |  |
| AXSOME THERAPEUTICS, INC.             | 05464T104 | 06/06/2025     | To approve, by non-binding advisory vote, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |          38500 |                0 | FOR         |                                    38500 | FOR                         |  |
| C4 THERAPEUTICS, INC.                 | 12529R107 | 06/18/2025     | To cast a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |        2174700 |                0 | FOR         |                                  2174700 | FOR                         |  |
| CORBUS PHARMACEUTICALS HOLDINGS, INC. | 21833P301 | 05/15/2025     | Approval, on an advisory basis, of the executive compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |         454087 |                0 | FOR         |                                   454087 | FOR                         |  |
| CRINETICS PHARMACEUTICALS INC.        | 22663K107 | 06/11/2025     | To consider and vote upon, on an advisory basis, the compensation of the Company's named executive officers as disclosed in the proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |          69600 |                0 | FOR         |                                    69600 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, to approve our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         549758 |                0 | FOR         |                                   549758 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, on the frequency of future advisory votes on our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         549758 |                0 | 1 YEAR      |                                   549758 | FOR                         |  |
| CYTOKINETICS, INCORPORATED            | 23282W605 | 05/14/2025     | To approve, on an advisory basis, the compensation of Cytokinetics, Incorporated's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         161907 |                0 | FOR         |                                   161907 | FOR                         |  |
| DISC MEDICINE, INC.                   | 254604101 | 06/11/2025     | To approve, on a non-binding, advisory basis, the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         186541 |                0 | FOR         |                                   186541 | FOR                         |  |
| DISC MEDICINE, INC.                   | 254604101 | 06/11/2025     | To recommend, by a non-binding advisory vote, the frequency of future advisory votes on the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |         186541 |                0 | 1 YEAR      |                                   186541 | FOR                         |  |
| DYNE THERAPEUTICS, INC.               | 26818M108 | 05/30/2025     | To vote, on an advisory basis, to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         271591 |                0 | AGAINST     |                                   271591 | AGAINST                     |  |
| DYNE THERAPEUTICS, INC.               | 26818M108 | 05/30/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         271591 |                0 | 1 YEAR      |                                   271591 | FOR                         |  |
| EDGEWISE THERAPEUTICS INC             | 28036F105 | 06/13/2025     | Conduct an advisory vote on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         171068 |                0 | FOR         |                                   171068 | FOR                         |  |
| EDGEWISE THERAPEUTICS INC             | 28036F105 | 06/13/2025     | Conduct an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         171068 |                0 | 1 YEAR      |                                   171068 | FOR                         |  |
| EXACT SCIENCES CORPORATION            | 30063P105 | 06/12/2025     | To approve, on an advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         103616 |                0 | FOR         |                                   103616 | FOR                         |  |
| FATE THERAPEUTICS, INC.               | 31189P102 | 05/29/2025     | To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers as disclosed in the proxy statement.                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         397600 |                0 | AGAINST     |                                   397600 | AGAINST                     |  |
| FATE THERAPEUTICS, INC.               | 31189P102 | 05/29/2025     | To recommend, on a non-binding advisory basis, the frequency of future non-binding stockholder advisory votes to approve the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         397600 |                0 | 1 YEAR      |                                   397600 | FOR                         |  |
| IONIS PHARMACEUTICALS, INC.           | 462222100 | 06/05/2025     | To make an advisory vote on executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         383000 |                0 | FOR         |                                   383000 | FOR                         |  |
| NATERA, INC.                          | 632307104 | 06/12/2025     | To approve, on an advisory (non-binding) basis, the compensation of Natera, Inc.'s named executive officers as disclosed in the proxy statement.                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |          56000 |                0 | FOR         |                                    56000 | FOR                         |  |
| NEUROCRINE BIOSCIENCES, INC.          | 64125C109 | 05/21/2025     | Advisory vote on the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         111800 |                0 | FOR         |                                   111800 | FOR                         |  |
| RAPT THERAPEUTICS, INC.               | 75382E109 | 05/29/2025     | To approve, on an advisory basis, the compensation of RAPT Therapeutics, Inc.'s named executive officers.                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |        6567630 |                0 | FOR         |                                  6567630 | FOR                         |  |
| RAPT THERAPEUTICS, INC.               | 75382E109 | 05/29/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of RAPT Therapeutics, Inc.'s named executive officers.                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |        6567630 |                0 | 1 YEAR      |                                  6567630 | FOR                         |  |
| RHYTHM PHARMACEUTICALS, INC.          | 76243J105 | 09/18/2024     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         162615 |                0 | FOR         |                                   162615 | FOR                         |  |
| RHYTHM PHARMACEUTICALS, INC.          | 76243J105 | 06/24/2025     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |          77274 |                0 | AGAINST     |                                    77274 | AGAINST                     |  |
| SCPHARMACEUTICALS INC.                | 810648105 | 06/03/2025     | To approve, on an advisory (non-binding) basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         252858 |                0 | FOR         |                                   252858 | FOR                         |  |
| SI-BONE, INC.                         | 825704109 | 06/05/2025     | Advisory vote to approve executive compensation "Say-on-Pay".                                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         473353 |                0 | FOR         |                                   473353 | FOR                         |  |
| STRUCTURE THERAPEUTICS, INC.          | 86366E106 | 06/23/2025     | TO APPROVE, ON AN ADVISORY BASIS, THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS, AS DISCLOSED IN THE PROXY STATEMENT.                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         294094 |                0 | FOR         |                                   294094 | FOR                         |  |
| STRUCTURE THERAPEUTICS, INC.          | 86366E106 | 06/23/2025     | TO INDICATE, ON AN ADVISORY BASIS, THE PREFERRED FREQUENCY OF SHAREHOLDER ADVISORY VOTES ON THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS.                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         294094 |                0 | 1 YEAR      |                                   294094 | FOR                         |  |
| TANGO THERAPEUTICS, INC.              | 87583X109 | 06/05/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         550000 |                0 | AGAINST     |                                   550000 | AGAINST                     |  |
| TANGO THERAPEUTICS, INC.              | 87583X109 | 06/05/2025     | Non-binding, advisory vote on the frequency of future non-binding, advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |         550000 |                0 | 1 YEAR      |                                   550000 | FOR                         |  |
| TARSUS PHARMACEUTICALS, INC.          | 87650L103 | 06/12/2025     | To hold an advisory vote to approve, on a non-binding basis, named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         247743 |                0 | FOR         |                                   247743 | FOR                         |  |
| TARSUS PHARMACEUTICALS, INC.          | 87650L103 | 06/12/2025     | To hold an advisory vote to approve, on a non-binding basis, the frequency with which future stockholder votes on the compensation of our named executive officers will be conducted of one, two or three years.                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         247743 |                0 | 1 YEAR      |                                   247743 | FOR                         |  |
| TREVI THERAPEUTICS INC                | 89532M101 | 06/11/2025     | Approval, on an advisory basis, of the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |         401000 |                0 | FOR         |                                   401000 | FOR                         |  |
| TREVI THERAPEUTICS INC                | 89532M101 | 06/11/2025     | Approval, on an advisory basis, of the frequency of future advisory votes to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         401000 |                0 | 1 YEAR      |                                   401000 | FOR                         |  |
| VERA THERAPEUTICS, INC.               | 92337R101 | 05/14/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         249602 |                0 | FOR         |                                   249602 | FOR                         |  |
| VERA THERAPEUTICS, INC.               | 92337R101 | 05/14/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         249602 |                0 | 1 YEAR      |                                   249602 | FOR                         |  |
| VERASTEM, INC.                        | 92337C203 | 05/22/2025     | To approve an advisory vote on the compensation of the named executive officers.                                                                                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         647215 |                0 | FOR         |                                   647215 | FOR                         |  |
| VIR BIOTECHNOLOGY, INC.               | 92764N102 | 05/29/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         627081 |                0 | FOR         |                                   627081 | FOR                         |  |
| WHITEHAWK THERAPEUTICS, INC.          | 00032Q104 | 06/11/2025     | To approve, on an advisory basis, the compensation of the named executive officers identified in the 2024 Summary Compensation Table in the 'Executive Compensation' section of the proxy statement.                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |        4166000 |                0 | FOR         |                                  4166000 | FOR                         |  |
| XENON PHARMACEUTICALS INC             | 98420N105 | 06/04/2025     | To approve, on an advisory basis, the compensation of the Corporation's named executive officers.                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         276890 |                0 | FOR         |                                   276890 | FOR                         |  |
| XERIS BIOPHARMA HOLDINGS, INC.        | 98422E103 | 06/04/2025     | To approve, on a non-binding advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |          11567 |                0 | FOR         |                                    11567 | FOR                         |  |
| ADICET BIO, INC.                      | 007002108 | 06/11/2025     | To ratify, on a non-binding advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        1674542 |                0 | FOR         |                                  1674542 | FOR                         |  |
| BIOMX INC.                            | 09090D103 | 07/09/2024     | To approve, on an advisory basis, the compensation of the Company's named executive officers as disclosed pursuant to Item 402 of Regulation S-K, including the compensation tables and narrative discussion related thereto.                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |       13773653 |                0 | FOR         |                                 13773653 | FOR                         |  |
| BIOMX INC.                            | 09090D103 | 07/09/2024     | To conduct a nonbinding advisory vote on the frequency (every one, two or three years) of future advisory votes on the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |       13773653 |                0 | 3 YEARS     |                                 13773653 | FOR                         |  |
| ADICET BIO, INC.                      | 007002108 | 06/11/2025     | To ratify, on a non-binding advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        8516613 |                0 | FOR         |                                  8516613 | FOR                         |  |
| AVALO THERAPEUTICS INC                | 05338F306 | 06/17/2025     | To approve, on a nonbinding advisory basis, a "Say-on-Pay" resolution regarding the compensensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         644667 |                0 | FOR         |                                   644667 | FOR                         |  |
| CORVUS PHARMACEUTICALS, INC.          | 221015100 | 06/12/2025     | To approve, on a non-binding advisory basis, the compensation of our named executive officers                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        6943654 |                0 | FOR         |                                  6943654 | FOR                         |  |
| CRINETICS PHARMACEUTICALS INC.        | 22663K107 | 06/11/2025     | To consider and vote upon, on an advisory basis, the compensation of the Company's named executive officers as disclosed in the proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |         999000 |                0 | FOR         |                                   999000 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, to approve our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         355306 |                0 | FOR         |                                   355306 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, on the frequency of future advisory votes on our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         355306 |                0 | 1 YEAR      |                                   355306 | FOR                         |  |
| DISC MEDICINE, INC.                   | 254604101 | 06/11/2025     | To approve, on a non-binding, advisory basis, the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |        1228479 |                0 | FOR         |                                  1228479 | FOR                         |  |
| DISC MEDICINE, INC.                   | 254604101 | 06/11/2025     | To recommend, by a non-binding advisory vote, the frequency of future advisory votes on the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |        1228479 |                0 | 1 YEAR      |                                  1228479 | FOR                         |  |
| EDGEWISE THERAPEUTICS INC             | 28036F105 | 06/13/2025     | Conduct an advisory vote on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |       14809075 |                0 | FOR         |                                 14809075 | FOR                         |  |
| EDGEWISE THERAPEUTICS INC             | 28036F105 | 06/13/2025     | Conduct an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |       14809075 |                0 | 1 YEAR      |                                 14809075 | FOR                         |  |
| JANUX THERAPEUTICS, INC.              | 47103J105 | 06/11/2025     | Approval, on an advisory basis, of the compensation of our named executive officers ("Say-On-Pay"), as disclosed in the accompanying Proxy Statement.                                                                                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |         720000 |                0 | FOR         |                                   720000 | FOR                         |  |
| JANUX THERAPEUTICS, INC.              | 47103J105 | 06/11/2025     | Indication, on an advisory basis, of the preferred frequency of holding future Say-On-Pay votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         720000 |                0 | 1 YEAR      |                                   720000 | FOR                         |  |
| KEROS THERAPEUTICS, INC.              | 492327101 | 06/04/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers as disclosed in the accompanying Proxy Statement.                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |        1018734 |                0 | FOR         |                                  1018734 | FOR                         |  |
| NEXTCURE, INC.                        | 65343E108 | 06/20/2025     | Approval, on an advisory basis, of the compensation paid by Company to its named executive officers.                                                                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         116470 |                0 | FOR         |                                   116470 | FOR                         |  |
| NEXTCURE, INC.                        | 65343E108 | 06/20/2025     | Approval, on an advisory basis, of whether a vote on the compensation of our named executive officers should take place every one year, every two years or every three years.                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         116470 |                0 | 1 YEAR      |                                   116470 | FOR                         |  |
| PMV PHARMACEUTICALS INC.              | 69353Y103 | 06/05/2025     | Approval, on a non-binding advisory basis, of the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |        6475291 |                0 | FOR         |                                  6475291 | FOR                         |  |
| Q32 BIO INC.                          | 746964105 | 06/13/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |        2252987 |                0 | FOR         |                                  2252987 | FOR                         |  |
| Q32 BIO INC.                          | 746964105 | 06/13/2025     | To approve, on a non-binding, advisory basis, the preferred frequency of future advisory votes on compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |        2252987 |                0 | 1 YEAR      |                                  2252987 | FOR                         |  |
| RAPT THERAPEUTICS, INC.               | 75382E109 | 05/29/2025     | To approve, on an advisory basis, the compensation of RAPT Therapeutics, Inc.'s named executive officers.                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |        6567630 |                0 | FOR         |                                  6567630 | FOR                         |  |
| RAPT THERAPEUTICS, INC.               | 75382E109 | 05/29/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of RAPT Therapeutics, Inc.'s named executive officers.                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |        6567630 |                0 | 1 YEAR      |                                  6567630 | FOR                         |  |
| REPARE THERAPEUTICS INC.              | 760273102 | 06/17/2025     | To approve, on an advisory basis, the compensation of our named executive officers, as disclosed in the accompanying proxy statement.                                                                                                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |        3177041 |                0 | FOR         |                                  3177041 | FOR                         |  |
| SCPHARMACEUTICALS INC.                | 810648105 | 06/03/2025     | To approve, on an advisory (non-binding) basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |        3230138 |                0 | FOR         |                                  3230138 | FOR                         |  |
| SPRINGWORKS THERAPEUTICS INC          | 85205L107 | 05/14/2025     | Non-binding advisory vote on executive compensation                                                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         920000 |                0 | FOR         |                                   920000 | FOR                         |  |
| VERASTEM, INC.                        | 92337C203 | 05/22/2025     | To approve an advisory vote on the compensation of the named executive officers.                                                                                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |        2215233 |                0 | FOR         |                                  2215233 | FOR                         |  |
| X4 PHARMACEUTICALS, INC.              | 98420X103 | 06/09/2025     | To hold a non-binding, advisory "say-on-pay" vote on the Company's executive compensation.                                                                                                                                                                                                                                                                                                                                                                                | SECTION 14A SAY-ON-PAY VOTES |        6776515 |                0 | FOR         |                                  6776515 | FOR                         |  |
| AKERO THERAPEUTICS, INC               | 00973Y108 | 06/03/2025     | To consider and act upon a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |          58200 |                0 | FOR         |                                    58200 | FOR                         |  |
| ALNYLAM PHARMACEUTICALS, INC.         | 02043Q107 | 05/08/2025     | To approve, in a non-binding advisory vote, the compensation of Alnylam's named executive officers.                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |          52900 |                0 | FOR         |                                    52900 | FOR                         |  |
| APELLIS PHARMACEUTICALS INC.          | 03753U106 | 06/03/2025     | To hold an advisory vote to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                | SECTION 14A SAY-ON-PAY VOTES |         128100 |                0 | FOR         |                                   128100 | FOR                         |  |
| APELLIS PHARMACEUTICALS INC.          | 03753U106 | 06/03/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         128100 |                0 | 1 YEAR      |                                   128100 | FOR                         |  |
| ARGENX SE                             | 04016X101 | 05/27/2025     | The 2024 remuneration report                                                                                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |          27100 |                0 | FOR         |                                    27100 | FOR                         |  |
| ASTRAZENECA PLC                       | G0593M107 | 04/11/2025     | TO APPROVE THE ANNUAL STATEMENT OF THE CHAIR OF THE REMUNERATION COMMITTEE AND THE ANNUAL REPORT ON REMUNERATION FOR THE YEAR ENDED 31 DECEMBER 2024                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         224000 |                0 | FOR         |                                   224000 | FOR                         |  |
| AVIDITY BIOSCIENCES, INC.             | 05370A108 | 06/10/2025     | To consider and vote upon, on an advisory basis, the compensation of our named executive officers as disclosed in this proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         396200 |                0 | AGAINST     |                                   396200 | AGAINST                     |  |
| AXSOME THERAPEUTICS, INC.             | 05464T104 | 06/06/2025     | To approve, by non-binding advisory vote, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |          44500 |                0 | FOR         |                                    44500 | FOR                         |  |
| BOSTON SCIENTIFIC CORPORATION         | 101137107 | 05/01/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         589500 |                0 | FOR         |                                   589500 | FOR                         |  |
| C4 THERAPEUTICS, INC.                 | 12529R107 | 06/18/2025     | To cast a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |        2904400 |                0 | FOR         |                                  2904400 | FOR                         |  |
| CRINETICS PHARMACEUTICALS INC.        | 22663K107 | 06/11/2025     | To consider and vote upon, on an advisory basis, the compensation of the Company's named executive officers as disclosed in the proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |          79900 |                0 | FOR         |                                    79900 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, to approve our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         602034 |                0 | FOR         |                                   602034 | FOR                         |  |
| CULLINAN THERAPEUTICS, INC.           | 230031106 | 06/12/2025     | Proposal to vote, on an advisory basis, on the frequency of future advisory votes on our named executive officer compensation.                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         602034 |                0 | 1 YEAR      |                                   602034 | FOR                         |  |
| CYTOKINETICS, INCORPORATED            | 23282W605 | 05/14/2025     | To approve, on an advisory basis, the compensation of Cytokinetics, Incorporated's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         177340 |                0 | FOR         |                                   177340 | FOR                         |  |
| DYNE THERAPEUTICS, INC.               | 26818M108 | 05/30/2025     | To vote, on an advisory basis, to approve the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         310600 |                0 | AGAINST     |                                   310600 | AGAINST                     |  |
| DYNE THERAPEUTICS, INC.               | 26818M108 | 05/30/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         310600 |                0 | 1 YEAR      |                                   310600 | FOR                         |  |
| EDWARDS LIFESCIENCES CORPORATION      | 28176E108 | 05/08/2025     | Advisory Vote to Approve Named Executive Officer Compensation                                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         268300 |                0 | FOR         |                                   268300 | FOR                         |  |
| ELI LILLY AND COMPANY                 | 532457108 | 05/05/2025     | Approval, on an advisory basis, of the compensation paid to the company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |          42600 |                0 | FOR         |                                    42600 | FOR                         |  |
| EXACT SCIENCES CORPORATION            | 30063P105 | 06/12/2025     | To approve, on an advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         130700 |                0 | FOR         |                                   130700 | FOR                         |  |
| FATE THERAPEUTICS, INC.               | 31189P102 | 05/29/2025     | To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers as disclosed in the proxy statement.                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         595980 |                0 | AGAINST     |                                   595980 | AGAINST                     |  |
| FATE THERAPEUTICS, INC.               | 31189P102 | 05/29/2025     | To recommend, on a non-binding advisory basis, the frequency of future non-binding stockholder advisory votes to approve the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |         595980 |                0 | 1 YEAR      |                                   595980 | FOR                         |  |
| INTEGER HOLDINGS CORPORATION          | 45826H109 | 05/21/2025     | To approve, on an advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         129700 |                0 | FOR         |                                   129700 | FOR                         |  |
| INTUITIVE SURGICAL, INC.              | 46120E602 | 05/01/2025     | To approve, by advisory vote, the compensation of the Company's Named Executive Officers.                                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |          56800 |                0 | FOR         |                                    56800 | FOR                         |  |
| IONIS PHARMACEUTICALS, INC.           | 462222100 | 06/05/2025     | To make an advisory vote on executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         435300 |                0 | FOR         |                                   435300 | FOR                         |  |
| NATERA, INC.                          | 632307104 | 06/12/2025     | To approve, on an advisory (non-binding) basis, the compensation of Natera, Inc.'s named executive officers as disclosed in the proxy statement.                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |          87000 |                0 | FOR         |                                    87000 | FOR                         |  |
| NEUROCRINE BIOSCIENCES, INC.          | 64125C109 | 05/21/2025     | Advisory vote on the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         126540 |                0 | FOR         |                                   126540 | FOR                         |  |
| NOVO NORDISK A/S                      | K72807140 | 03/27/2025     | PRESENTATION OF AND ADVISORY VOTE ON THE REMUNERATION REPORT 2024                                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |          55900 |                0 | FOR         |                                    55900 | FOR                         |  |
| PFIZER INC.                           | 717081103 | 04/24/2025     | 2025 advisory approval of executive compensation                                                                                                                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         567900 |                0 | FOR         |                                   567900 | FOR                         |  |
| REPARE THERAPEUTICS INC.              | 760273102 | 06/17/2025     | To approve, on an advisory basis, the compensation of our named executive officers, as disclosed in the accompanying proxy statement.                                                                                                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |          96190 |                0 | FOR         |                                    96190 | FOR                         |  |
| RHYTHM PHARMACEUTICALS, INC.          | 76243J105 | 09/18/2024     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         249527 |                0 | FOR         |                                   249527 | FOR                         |  |
| RHYTHM PHARMACEUTICALS, INC.          | 76243J105 | 06/24/2025     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |          92013 |                0 | AGAINST     |                                    92013 | AGAINST                     |  |
| SI-BONE, INC.                         | 825704109 | 06/05/2025     | Advisory vote to approve executive compensation "Say-on-Pay".                                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         669500 |                0 | FOR         |                                   669500 | FOR                         |  |
| STRUCTURE THERAPEUTICS, INC.          | 86366E106 | 06/23/2025     | TO APPROVE, ON AN ADVISORY BASIS, THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS, AS DISCLOSED IN THE PROXY STATEMENT.                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |          19100 |                0 | FOR         |                                    19100 | FOR                         |  |
| STRUCTURE THERAPEUTICS, INC.          | 86366E106 | 06/23/2025     | TO INDICATE, ON AN ADVISORY BASIS, THE PREFERRED FREQUENCY OF SHAREHOLDER ADVISORY VOTES ON THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS.                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |          19100 |                0 | 1 YEAR      |                                    19100 | FOR                         |  |
| STRYKER CORPORATION                   | 863667101 | 05/08/2025     | Advisory Vote to Approve Named Executive Officer Compensation.                                                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |          61200 |                0 | FOR         |                                    61200 | FOR                         |  |
| TARSUS PHARMACEUTICALS, INC.          | 87650L103 | 06/12/2025     | To hold an advisory vote to approve, on a non-binding basis, named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         188000 |                0 | FOR         |                                   188000 | FOR                         |  |
| TARSUS PHARMACEUTICALS, INC.          | 87650L103 | 06/12/2025     | To hold an advisory vote to approve, on a non-binding basis, the frequency with which future stockholder votes on the compensation of our named executive officers will be conducted of one, two or three years.                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         188000 |                0 | 1 YEAR      |                                   188000 | FOR                         |  |
| TENET HEALTHCARE CORPORATION          | 88033G407 | 05/22/2025     | To approve, on an advisory basis, the Company's executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |          90000 |                0 | FOR         |                                    90000 | FOR                         |  |
| THERMO FISHER SCIENTIFIC INC.         | 883556102 | 05/21/2025     | An advisory vote to approve named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |          17000 |                0 | AGAINST     |                                    17000 | AGAINST                     |  |
| UCB SA                                | B93562120 | 04/24/2025     | APPROVAL OF THE REMUNERATION REPORT FOR THE FINANCIAL YEAR ENDED 31 DECEMBER 2024                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |           8900 |                0 | FOR         |                                     8900 | FOR                         |  |
| VERA THERAPEUTICS, INC.               | 92337R101 | 05/14/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |         189470 |                0 | FOR         |                                   189470 | FOR                         |  |
| VERA THERAPEUTICS, INC.               | 92337R101 | 05/14/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         189470 |                0 | 1 YEAR      |                                   189470 | FOR                         |  |
| VERTEX PHARMACEUTICALS INCORPORATED   | 92532F100 | 05/14/2025     | Advisory vote to approve named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |          25200 |                0 | FOR         |                                    25200 | FOR                         |  |
| VIR BIOTECHNOLOGY, INC.               | 92764N102 | 05/29/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         709235 |                0 | FOR         |                                   709235 | FOR                         |  |
| XENON PHARMACEUTICALS INC             | 98420N105 | 06/04/2025     | To approve, on an advisory basis, the compensation of the Corporation's named executive officers.                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         351687 |                0 | FOR         |                                   351687 | FOR                         |  |
| ABCELLERA BIOLOGICS INC.              | 00288U106 | 06/12/2025     | To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers, or Say-on-Pay.                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |        4180768 |                0 | FOR         |                                  4180768 | FOR                         |  |
| XTANT MEDICAL HOLDINGS, INC.          | 98420P308 | 07/23/2024     | To approve, on an advisory basis, the compensation of the Company's executive officers named in the accompanying proxy statement.                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |       73114592 |                0 | FOR         |                                 73114592 | FOR                         |  |
| ALNYLAM PHARMACEUTICALS, INC.         | 02043Q107 | 05/08/2025     | To approve, in a non-binding advisory vote, the compensation of Alnylam's named executive officers.                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         109402 |                0 | FOR         |                                   109402 | FOR                         |  |
| APELLIS PHARMACEUTICALS INC.          | 03753U106 | 06/03/2025     | To hold an advisory vote to approve the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                | SECTION 14A SAY-ON-PAY VOTES |        1189000 |                0 | FOR         |                                  1189000 | FOR                         |  |
| APELLIS PHARMACEUTICALS INC.          | 03753U106 | 06/03/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation paid to our named executive officers.                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |        1189000 |                0 | 1 YEAR      |                                  1189000 | FOR                         |  |
| ARGENX SE                             | 04016X101 | 05/27/2025     | The 2024 remuneration report                                                                                                                                                                                                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |         125000 |                0 | FOR         |                                   125000 | FOR                         |  |
| ASTRAZENECA PLC                       | G0593M107 | 04/11/2025     | TO APPROVE THE ANNUAL STATEMENT OF THE CHAIR OF THE REMUNERATION COMMITTEE AND THE ANNUAL REPORT ON REMUNERATION FOR THE YEAR ENDED 31 DECEMBER 2024                                                                                                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES |        1054300 |                0 | FOR         |                                  1054300 | FOR                         |  |
| AVIDITY BIOSCIENCES, INC.             | 05370A108 | 06/10/2025     | To consider and vote upon, on an advisory basis, the compensation of our named executive officers as disclosed in this proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission.                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |         700000 |                0 | AGAINST     |                                   700000 | AGAINST                     |  |
| AXSOME THERAPEUTICS, INC.             | 05464T104 | 06/06/2025     | To approve, by non-binding advisory vote, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |         239600 |                0 | FOR         |                                   239600 | FOR                         |  |
| BOSTON SCIENTIFIC CORPORATION         | 101137107 | 05/01/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |        2223700 |                0 | FOR         |                                  2223700 | FOR                         |  |
| CYTOKINETICS, INCORPORATED            | 23282W605 | 05/14/2025     | To approve, on an advisory basis, the compensation of Cytokinetics, Incorporated's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         999658 |                0 | FOR         |                                   999658 | FOR                         |  |
| EDWARDS LIFESCIENCES CORPORATION      | 28176E108 | 05/08/2025     | Advisory Vote to Approve Named Executive Officer Compensation                                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        1103000 |                0 | FOR         |                                  1103000 | FOR                         |  |
| ELI LILLY AND COMPANY                 | 532457108 | 05/05/2025     | Approval, on an advisory basis, of the compensation paid to the company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         295000 |                0 | FOR         |                                   295000 | FOR                         |  |
| EXACT SCIENCES CORPORATION            | 30063P105 | 06/12/2025     | To approve, on an advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         152389 |                0 | FOR         |                                   152389 | FOR                         |  |
| INTEGER HOLDINGS CORPORATION          | 45826H109 | 05/21/2025     | To approve, on an advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |         532800 |                0 | FOR         |                                   532800 | FOR                         |  |
| INTUITIVE SURGICAL, INC.              | 46120E602 | 05/01/2025     | To approve, by advisory vote, the compensation of the Company's Named Executive Officers.                                                                                                                                                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |         234200 |                0 | FOR         |                                   234200 | FOR                         |  |
| IONIS PHARMACEUTICALS, INC.           | 462222100 | 06/05/2025     | To make an advisory vote on executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES |        1441536 |                0 | FOR         |                                  1441536 | FOR                         |  |
| NATERA, INC.                          | 632307104 | 06/12/2025     | To approve, on an advisory (non-binding) basis, the compensation of Natera, Inc.'s named executive officers as disclosed in the proxy statement.                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |         401363 |                0 | FOR         |                                   401363 | FOR                         |  |
| NEUROCRINE BIOSCIENCES, INC.          | 64125C109 | 05/21/2025     | Advisory vote on the compensation paid to the Company's named executive officers.                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         501980 |                0 | FOR         |                                   501980 | FOR                         |  |
| NOVO NORDISK A/S                      | K72807140 | 03/27/2025     | PRESENTATION OF AND ADVISORY VOTE ON THE REMUNERATION REPORT 2024                                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         494300 |                0 | FOR         |                                   494300 | FOR                         |  |
| PFIZER INC.                           | 717081103 | 04/24/2025     | 2025 advisory approval of executive compensation                                                                                                                                                                                                                                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |        3282300 |                0 | FOR         |                                  3282300 | FOR                         |  |
| SI-BONE, INC.                         | 825704109 | 06/05/2025     | Advisory vote to approve executive compensation "Say-on-Pay".                                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |        2300000 |                0 | FOR         |                                  2300000 | FOR                         |  |
| STRYKER CORPORATION                   | 863667101 | 05/08/2025     | Advisory Vote to Approve Named Executive Officer Compensation.                                                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         283200 |                0 | FOR         |                                   283200 | FOR                         |  |
| TENET HEALTHCARE CORPORATION          | 88033G407 | 05/22/2025     | To approve, on an advisory basis, the Company's executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |         375000 |                0 | FOR         |                                   375000 | FOR                         |  |
| THERMO FISHER SCIENTIFIC INC.         | 883556102 | 05/21/2025     | An advisory vote to approve named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |          87000 |                0 | AGAINST     |                                    87000 | AGAINST                     |  |
| UCB SA                                | B93562120 | 04/24/2025     | APPROVAL OF THE REMUNERATION REPORT FOR THE FINANCIAL YEAR ENDED 31 DECEMBER 2024                                                                                                                                                                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |         124500 |                0 | FOR         |                                   124500 | FOR                         |  |
| UNITEDHEALTH GROUP INCORPORATED       | 91324P102 | 06/02/2025     | Advisory approval of the Company's executive compensation.                                                                                                                                                                                                                                                                                                                                                                                                                | SECTION 14A SAY-ON-PAY VOTES |         189600 |                0 | FOR         |                                   189600 | FOR                         |  |
| VERTEX PHARMACEUTICALS INCORPORATED   | 92532F100 | 05/14/2025     | Advisory vote to approve named executive officer compensation.                                                                                                                                                                                                                                                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES |         109500 |                0 | FOR         |                                   109500 | FOR                         |  |
| WORLDWIDE HEALTHCARE TRUST PLC        | G9779G123 | 07/10/2024     | TO APPROVE THE DIRECTORS REMUNERATION REPORT FOR THE YEAR ENDED 31 MARCH 2024                                                                                                                                                                                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |         891416 |                0 | FOR         |                                   891416 | FOR                         |  |

## N-PX: Signature Block

**Reporting Person:** OrbiMed Advisors LLC

**By (Signature):** Sven H. Borho

**By (Printed Signature):** Sven H. Borho

**By (Title):** Member

**Date:** 08/29/2025