# EDGAR Filing Document

**Accession Number:** 0000836487
**File Stem:** 0001752724-25-199158
**Filing Date:** 2025-8
**Character Count:** 16381
**Document Hash:** 460fa741c6283f6e4ca7c4264b95eeeb
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-25-199158.hdr.sgml**: 20250822

**ACCESSION NUMBER**: 0001752724-25-199158

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250822

**DATE AS OF CHANGE**: 20250822

**PERIOD START**: 20251231

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MORGAN STANLEY INSTITUTIONAL FUND INC
- **CENTRAL INDEX KEY:** 0000836487

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MD
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-05624
- **FILM NUMBER:** 251244167

**BUSINESS ADDRESS:**
- **STREET 1:** 1585 BROADWAY
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10036
- **BUSINESS PHONE:** 800-548-7786

**MAIL ADDRESS:**
- **STREET 1:** 1585 BROADWAY
- **CITY:** NEW YORK
- **STATE:** NY
- **ZIP:** 10036

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MORGAN STANLEY DEAN WITTER INSTITUTIONAL FUND INC
- **DATE OF NAME CHANGE:** 19990329

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MORGAN STANLEY INSTITUTIONAL FUND INC
- **DATE OF NAME CHANGE:** 19920703

## Series and Classes Contracts Data

### Vitality Portfolio (Series ID: S000074797)

| Class ID   | Class Name   | Ticker Symbol   |
|:---|:---|:---|
| C000233002 | Class I      | MSVDX           |
| C000233003 | Class A      | MSVEX           |
| C000233004 | Class C      | MSVMX           |
| C000233005 | Class R6     | MSVOX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** MORGAN STANLEY INSTITUTIONAL FUND INC

- **b. Investment Company Act file number:** 811-05624

- **c. CIK number of Registrant:** 0000836487

- **d. LEI of Registrant:** 54930067DYRSUSGS4E97

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 1585 Broadway

  - **City:** NEW YORK

  - **State:** NY

  - **Foreign country:** US

  - **Zip / Postal Code:** 10036

  - **Telephone number:** 800-869-6397

**Item A.2. Information about the Series.**

- **a. Name of Series:** Vitality Portfolio

- **b. EDGAR series identifier (if any):** S000074797

- **c. LEI of Series:** 549300V9WWJX6LPH4Y61

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-12-31

- **b. Date as of which information is reported:** 2025-06-30

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $1925175.10

**Total Liabilities:** $67100.33

**Net Assets:** $1858074.77

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000233003 | 2.26%                | -4.60%               | 2.32%                |
| Class ID C000233002 | 2.24%                | -4.57%               | 2.30%                |
| Class ID C000233004 | 2.10%                | -4.49%               | 2.16%                |
| Class ID C000233005 | 2.43%                | -4.56%               | 2.29%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $16205.40                | $27307.70                                  |
| Month 2  | $-46850.48               | $-39061.65                                 |
| Month 3  | $-62428.51               | $105496.87                                 |

### Schedule of Portfolio Investments

| Name                                               | Title                                                                        | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| 10X Genomics Inc                                   | 10X Genomics Inc                                                             | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |      3801 | NS      | $44015.58     | 2.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc                        | Alnylam Pharmaceuticals Inc                                                  | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |       335 | NS      | $109240.15    | 5.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Newamsterdam Pharma Co NV                          | Newamsterdam Pharma Co NV                                                    | CUSIP: 000000000<br>LEI: 984500B6549TF6E14D36 | Long             | EC               | CORP              | NL        |      2383 | NS      | $43156.13     | 2.32%             |  |  |  | No            |                  1 | On Loan: —       |
| Vertex Pharmaceuticals Inc                         | Vertex Pharmaceuticals Inc                                                   | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |       169 | NS      | $75238.80     | 4.05%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc                             | UnitedHealth Group Inc                                                       | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |       222 | NS      | $69257.34     | 3.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corp                                | Exact Sciences Corp                                                          | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |      2200 | NS      | $116908.00    | 6.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Merrill Lynch, Pierce, Fenner & Smith Incorporated | MERRILL LYNCH TRI PARTY A REPO                                               | CUSIP: 000000000<br>LEI: 8NAV47T0Y26Q87Y0QP81 | Long             | RA               | CORP              | US        |     10419 | PA      | $10418.86     | 0.56%             |  |  |  | No            |                  2 | On Loan: No      |
| agilon health Inc                                  | agilon health Inc                                                            | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7516 | NS      | $17286.80     | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc                       | Thermo Fisher Scientific Inc                                                 | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |       186 | NS      | $75415.56     | 4.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc                              | Beam Therapeutics Inc                                                        | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       951 | NS      | $16176.51     | 0.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Ascendis Pharma A/S                                | Ascendis Pharma A/S                                                          | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |       512 | NS      | $88371.20     | 4.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc                          | Intellia Therapeutics Inc                                                    | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |      5293 | NS      | $49648.34     | 2.67%             |  |  |  | No            |                  1 | On Loan: —       |
| Zoetis Inc                                         | Zoetis Inc                                                                   | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |       411 | NS      | $64095.45     | 3.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc                        | Inspire Medical Systems Inc                                                  | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |       406 | NS      | $52686.62     | 2.84%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc                               | Align Technology Inc                                                         | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |       433 | NS      | $81979.89     | 4.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                                  | Veeva Systems Inc                                                            | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |       190 | NS      | $54716.20     | 2.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                                       | Biohaven Ltd                                                                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | VG        |      1286 | NS      | $18145.46     | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Morgan Stanley & Co. LLC                           | Morgan Stanley Institutional Liquidity Funds - Treasury Securities Portfolio | CUSIP: 61747C525<br>LEI: 549300OJY9IZ31SGS926 | Long             | STIV             | RF                | US        |    141537 | NS      | $141537.26    | 7.62%             |  |  |  | No            |                  1 | On Loan: No      |
| ATAI Life Sciences NV                              | ATAI Life Sciences NV                                                        | CUSIP: 000000000<br>LEI: 391200Z8UWPJSNBNCA11 | Long             | EC               | CORP              | NL        |     14368 | NS      | $31465.92     | 1.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Structure Therapeutics Inc                         | Structure Therapeutics Inc                                                   | CUSIP: 86366E106<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |      1787 | NS      | $37062.38     | 1.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                                       | Illumina Inc                                                                 | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |       295 | NS      | $28145.95     | 1.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Doximity Inc                                       | Doximity Inc                                                                 | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1037 | NS      | $63609.58     | 3.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc                             | Intuitive Surgical Inc                                                       | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |       132 | NS      | $71730.12     | 3.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Argenx SE                                          | Argenx SE                                                                    | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |       241 | NS      | $132844.02    | 7.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc                           | Enliven Therapeutics Inc                                                     | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1067 | NS      | $21404.02     | 1.15%             |  |  |  | No            |                  1 | On Loan: —       |
| Schrodinger Inc/United States                      | Schrodinger Inc/United States                                                | CUSIP: 80810D103<br>LEI: 984500044BAE4791E559 | Long             | EC               | CORP              | US        |      2552 | NS      | $51346.24     | 2.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceutical Inc                      | Ultragenyx Pharmaceutical Inc                                                | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |       758 | NS      | $27560.88     | 1.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Morgan Stanley & Co. LLC                           | Morgan Stanley Institutional Liquidity Funds - Treasury Securities Portfolio | CUSIP: 61747C525<br>LEI: 549300OJY9IZ31SGS926 | Long             | STIV             | RF                | US        |     59040 | NS      | $59040.21     | 3.18%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Inc                   | West Pharmaceutical Services Inc                                             | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |       146 | NS      | $31944.80     | 1.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                                     | Eli Lilly & Co                                                               | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |       181 | NS      | $141094.93    | 7.59%             |  |  |  | No            |                  1 | On Loan: No      |
| MaxCyte Inc                                        | MaxCyte Inc                                                                  | CUSIP: 57777K106<br>LEI: 54930053YHXULRFCU991 | Long             | EC               | CORP              | US        |     21067 | NS      | $45926.06     | 2.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Citigroup Global Markets Inc                       | Citigroup Global Markets Inc                                                 | CUSIP: 000000000<br>LEI: MBNUM2BPBDO7JBLYG310 | Long             | RA               | CORP              | US        |      4793 | PA      | $4792.68      | 0.26%             |  |  |  | No            |                  2 | On Loan: No      |

### Signature

**Date Signed:** 2025-07-21

**Name of Applicant:** MORGAN STANLEY INSTITUTIONAL FUND INC

**Signature:** Francis Smith

**Name of Signer:** Francis Smith

**Title:** Principal Financial Officer