# EDGAR Filing Document

**Accession Number:** 0001727196
**File Stem:** 0001980298-25-000007
**Filing Date:** 2025-12
**Character Count:** 9801
**Document Hash:** 4975685616498cd7d3025cadf0e58e6c
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001980298-25-000007.hdr.sgml**: 20251205

**ACCESSION NUMBER**: 0001980298-25-000007

**CONFORMED SUBMISSION TYPE**: 4

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20251204

**FILED AS OF DATE**: 20251205

**DATE AS OF CHANGE**: 20251205

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Qatanani Mo
- **CENTRAL INDEX KEY:** 0001980298

**ORGANIZATION NAME:**

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-38501
- **FILM NUMBER:** 251553618

**MAIL ADDRESS:**
- **STREET 1:** 301 BINNEY STREET, 3RD FLOOR
- **STREET 2:** C/O SCHOLAR ROCK HOLDING CORP
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02142
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Scholar Rock Holding Corp
- **CENTRAL INDEX KEY:** 0001727196
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 823750435
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 301 BINNEY STREET
- **STREET 2:** 3RD FLOOR
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02142
- **BUSINESS PHONE:** 857-259-3860

**MAIL ADDRESS:**
- **STREET 1:** 301 BINNEY STREET
- **STREET 2:** 3RD FLOOR
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02142

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 4

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[x] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Qatanani Mo<br><sub>(Last) (First) (Middle)</sub><br>301 BINNEY STREET<br><sub>(Street)</sub><br>CAMBRIDGE, MA 02142<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2025-12-04 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director [ ] 10% Owner<br>[X] Officer (give title below) [ ] Other (specify below)<br>_CHIEF SCIENTIFIC OFFICER_ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>Scholar Rock Holding Corp [ SRRK ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[X] Form filed by One Reporting Person<br>[ ] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Common Stock | 2025-12-04 |  | M |  | 65625<sup>(1)</sup> | A | $26.05 | 174589<sup>(2)</sup> | D |  |
| Common Stock | 2025-12-04 |  | M |  | 21093<sup>(1)</sup> | A | $18.08 | 195682<sup>(3)</sup> | D |  |
| Common Stock | 2025-12-04 |  | M |  | 5607<sup>(1)</sup> | A | $4.86 | 201289<sup>(4)</sup> | D |  |
| Common Stock | 2025-12-04 |  | M |  | 1281<sup>(1)</sup> | A | $7.62 | 202570<sup>(5)</sup> | D |  |
| Common Stock | 2025-12-04 |  | M |  | 11250<sup>(1)</sup> | A | $10 | 213820<sup>(6)</sup> | D |  |
| Common Stock | 2025-12-04 |  | M |  | 23571<sup>(1)</sup> | A | $15.75 | 237391<sup>(7)</sup> | D |  |
| Common Stock | 2025-12-04 |  | M |  | 8035<sup>(1)</sup> | A | $35.15 | 245426<sup>(8)</sup> | D |  |
| Common Stock | 2025-12-04 |  | S |  | 136462<sup>(1)</sup> | D | 45.2125<sup>(9)</sup> | 108964<sup>(10)</sup> | D |  |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| Stock Option (Right to Buy) | $26.05 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 65625 | <sup>(11)</sup> | 2031-10-26 | Common Stock | 65625 | $0 | 4375 | D |  |
| Stock Option (Right to Buy) | $18.08 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 21093 | <sup>(12)</sup> | 2032-02-14 | Common Stock | 21093 | $0 | 1407 | D |  |
| Stock Option (Right to Buy) | $4.86 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 5607 | <sup>(11)</sup> | 2032-06-16 | Common Stock | 5607 | $0 | 0 | D |  |
| Stock Option (Right to Buy) | $7.62 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 1281 | <sup>(11)</sup> | 2032-10-10 | Common Stock | 1281 | $0 | 1282 | D |  |
| Stock Option (Right to Buy) | $10 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 11250 | <sup>(13)</sup> | 2033-02-13 | Common Stock | 11250 | $0 | 14063 | D |  |
| Stock Option (Right to Buy) | $15.75 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 23571 | <sup>(14)</sup> | 2034-12-12 | Common Stock | 23571 | $0 | 53036 | D |  |
| Stock Option (Right to Buy) | $35.15 | 2025-12-04 |  | M<sup>(1)</sup> |  |  | 8035 | <sup>(15)</sup> | 2035-03-10 | Common Stock | 8035 | $0 | 34820 | D |  |

---

### Footnotes:

(1) This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025.

(2) Consists of 65,625 shares of common stock and 108,964 RSUs.

(3) Consists of 86,718 shares of common stock and 108,964 RSUs.

(4) Consists of 92,325 shares of common stock and 108,964 RSUs

(5) Consists of 93,606 shares of common stock and 108,964 RSUs.

(6) Consists of 104,856 shares of common stock and 108,964 RSUs.

(7) Consists of 128,427 shares of common stock and 108,964 RSUs.

(8) Consists of 136,462 shares of common stock and 108,964 RSUs.

(9) The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.00 to $45.46, inclusive.  Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

(10) Consists of 108,964 RSUs.

(11) 1,282 shares remain unvested under this stock option. The first vesting event occurred on January 5, 2023 and the remainder vest in fifteen quarterly installments thereafter; provided the reporting person continues to have a service relationship with the Issuer on such vesting date.

(12) 1,407 shares remain unvested under this stock option. The first vesting event occurred on April 1, 2022 and the remainder vests in fifteen quarterly installments thereafter; provided the Reporting Person continues to have a service relationship with the Issuer on such vesting date.

(13) 14,063 shares remain unvested under this stock option. The first vesting event occurred on April 1, 2023 and the remainder vests in fifteen quarterly installments thereafter; provided the Reporting Person continues to have a service relationship with the Issuer on such vesting date.

(14) 53,036 shares remain unvested under this stock option. The first vesting event occurred on April 1, 2024 and the remainder vests in fifteen quarterly installments thereafter; provided the Reporting Person continues to have a service relationship with the Issuer on such vesting date.

(15) 34,820 shares remain unvested under this stock option. The first vesting event occurred on April 1, 2025 and the remainder vests in fifteen quarterly installments thereafter; provided the Reporting Person continues to have a service relationship with the Issuer on such vesting date.

**Signature:** /s/ Junlin Ho, Attorney-in-Fact for Mo Qatanani  
**Date:** 2025-12-05

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**