# EDGAR Filing Document

**Accession Number:** 0001472322
**File Stem:** 0001104659-25-078700
**Filing Date:** 2025-8
**Character Count:** 19975
**Document Hash:** 097c84fba17ca25d5fb0f7a35e58f5ac
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-078700.hdr.sgml**: 20250814

**ACCESSION NUMBER**: 0001104659-25-078700

**CONFORMED SUBMISSION TYPE**: 13F-HR

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250814

**DATE AS OF CHANGE**: 20250814

**EFFECTIVENESS DATE**: 20250814

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Nantahala Capital Management, LLC
- **CENTRAL INDEX KEY:** 0001472322

**ORGANIZATION NAME:**
- **EIN:** 201151760
- **STATE OF INCORPORATION:** MA
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 13F-HR
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-14750
- **FILM NUMBER:** 251220172

**BUSINESS ADDRESS:**
- **STREET 1:** 130 MAIN ST.
- **STREET 2:** 2ND FLOOR
- **CITY:** NEW CANAAN
- **STATE:** CT
- **ZIP:** 06840
- **BUSINESS PHONE:** 203-404-1172

**MAIL ADDRESS:**
- **STREET 1:** 130 MAIN ST.
- **STREET 2:** 2ND FLOOR
- **CITY:** NEW CANAAN
- **STATE:** CT
- **ZIP:** 06840

### FORM 13F COVER PAGE

**Report for the Calendar Year or Quarter Ended:** 06-30-2025

**Check here if Amendment** [ ] **Amendment Number:** 

**This Amendment (Check only one.):** [ ] is a restatement.

[ ] adds new holdings entries.

**Institutional Investment Manager Filing this Report:**

**Name:** Nantahala Capital Management LLC<br>**Address:** 130 Main St.<br>2nd Floor<br>New Canaan, CT 06840

**Form 13F File Number:** 028-14750

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

**Person Signing this Report on Behalf of Reporting Manager:**

**Name:** Taki Vasilakis<br>**Title:** Chief Compliance Officer<br>**Phone:** 203-308-4440

**Signature, Place, and Date of Signing:**

/s/ Taki Vasilakis  New Canaan, CT  08-14-2025<br>[Signature]  [City, State]  [Date]

**Report Type (Check only one.):**

[x] **13F HOLDINGS REPORT.** (Check here if all holdings of this reporting manager are reported in this report.)

[ ] **13F NOTICE.** (Check here if no holdings are reported in this report, and all holdings are reported by other reporting manager(s).)

[ ] **13F COMBINATION REPORT.** (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)

### Form 13F Summary Page

**Report Summary:**

**Number of Other Included Managers:** 0

**Form 13F Information Table Entry Total:** 158

**Form 13F Information Table Value Total:** $2552295036

      (round to nearest dollar)

**List of Other Included Managers:**

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.

[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]

**NONE**

### FORM 13F INFORMATION TABLE

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | VOTING AUTHORITY | VOTING AUTHORITY | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | VALUE (x$1000) | SHRS OR PRN AMT | SH/PRN | PUT/CALL | INVESTMENT DISCRETION | OTHER MANAGER | SOLE | SHARED | NONE |
| 1 800 FLOWERS COM INC | CL A | 68243Q106 |  | 9840000 | 2000000 | SH |  | SOLE |  | 2000000 | 0 | 0 |
| ABEONA THERAPEUTICS INC | COM NEW | 00289Y206 |  | 24819697 | 4369665 | SH |  | SOLE |  | 4369665 | 0 | 0 |
| ABEONA THERAPEUTICS INC | COM NEW | 00289Y206 |  | 2953600 | 520000 | SH | Call | SOLE |  | 520000 | 0 | 0 |
| ABIVAX SA | SPONSORED ADS | 00370M103 |  | 11344904 | 1482994 | SH |  | SOLE |  | 1482994 | 0 | 0 |
| ACHIEVE LIFE SCIENCES INC | COM | 004468500 |  | 2031480 | 898885 | SH |  | SOLE |  | 898885 | 0 | 0 |
| ACME UTD CORP | COM | 004816104 |  | 846699 | 20427 | SH |  | SOLE |  | 20427 | 0 | 0 |
| ADC THERAPEUTICS SA | SHS | H0036K147 |  | 6073655 | 2266289 | SH |  | SOLE |  | 2266289 | 0 | 0 |
| AKEBIA THERAPEUTICS INC | COM | 00972D105 |  | 7280000 | 2000000 | SH |  | SOLE |  | 2000000 | 0 | 0 |
| ALTA EQUIPMENT GROUP INC | COMMON STOCK | 02128L106 |  | 6590300 | 1042769 | SH |  | SOLE |  | 1042769 | 0 | 0 |
| ALTISOURCE PORTFOLIO SOLUTIO | *W EXP 04/02/202 | L0175J120 |  | 1238656 | 2477312 | SH |  | SOLE |  | 2477312 | 0 | 0 |
| ALTISOURCE PORTFOLIO SOLUTIO | *W EXP 04/30/203 | L0175J112 |  | 1263429 | 2477312 | SH |  | SOLE |  | 2477312 | 0 | 0 |
| ALTISOURCE PORTFOLIO SOLUTIO | REG SHS | L0175J104 |  | 1156677 | 135601 | SH |  | SOLE |  | 135601 | 0 | 0 |
| AMERICAS CAR-MART INC | COM | 03062T105 |  | 36128203 | 644686 | SH |  | SOLE |  | 644686 | 0 | 0 |
| AMNEAL PHARMACEUTICALS INC | COM STK CL A | 03168L105 |  | 35332573 | 4367438 | SH |  | SOLE |  | 4367438 | 0 | 0 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 |  | 18809536 | 2934405 | SH |  | SOLE |  | 2934405 | 0 | 0 |
| ANEBULO PHARMACEUTICALS INC | COM | 034569103 |  | 4372308 | 3036325 | SH |  | SOLE |  | 3036325 | 0 | 0 |
| ANTERIS TECHNOLOGIES GLOBAL | COM | 03675P102 |  | 6418994 | 1693666 | SH |  | SOLE |  | 1693666 | 0 | 0 |
| APREA THERAPEUTICS INC | COM NEW | 03836J201 |  | 347734 | 205760 | SH |  | SOLE |  | 205760 | 0 | 0 |
| APYX MEDICAL CORPORATION | COM | 03837C106 |  | 7510608 | 3338048 | SH |  | SOLE |  | 3338048 | 0 | 0 |
| ASSERTIO HOLDINGS INC | COM NEW | 04546C205 |  | 5649019 | 8810073 | SH |  | SOLE |  | 8810073 | 0 | 0 |
| ASTRIA THERAPEUTICS INC | COM | 04635X102 |  | 5732681 | 1069530 | SH |  | SOLE |  | 1069530 | 0 | 0 |
| AURA BIOSCIENCES INC | COM | 05153U107 |  | 13256783 | 2117697 | SH |  | SOLE |  | 2117697 | 0 | 0 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 |  | 4965050 | 995000 | SH |  | SOLE |  | 995000 | 0 | 0 |
| AYTU BIOPHARMA INC | COM | 054754858 |  | 2369250 | 1086812 | SH |  | SOLE |  | 1086812 | 0 | 0 |
| BANCORP INC DEL | COM | 05969A105 |  | 55175616 | 968503 | SH |  | SOLE |  | 968503 | 0 | 0 |
| BENITEC BIOPHARMA INC | COM NEW | 08205P209 |  | 9805712 | 838095 | SH |  | SOLE |  | 838095 | 0 | 0 |
| BIODESIX INC | COM | 09075X108 |  | 23960 | 84903 | SH |  | SOLE |  | 84903 | 0 | 0 |
| BIOMX INC | COM NEW | 09090D301 |  | 1121989 | 2493309 | SH |  | SOLE |  | 2493309 | 0 | 0 |
| BIOVENTUS INC | COM CL A | 09075A108 |  | 34959174 | 5280842 | SH |  | SOLE |  | 5280842 | 0 | 0 |
| CAESARS ENTERTAINMENT INC NE | COM | 12769G100 |  | 2807175 | 98879 | SH |  | SOLE |  | 98879 | 0 | 0 |
| CAESARS ENTERTAINMENT INC NE | COM | 12769G100 |  | 14195000 | 500000 | SH | Call | SOLE |  | 500000 | 0 | 0 |
| CAMPING WORLD HLDGS INC | CL A | 13462K109 |  | 17190000 | 1000000 | SH | Call | SOLE |  | 1000000 | 0 | 0 |
| CARGO THERAPEUTICS INC | COM | 14179K101 |  | 4532000 | 1100000 | SH |  | SOLE |  | 1100000 | 0 | 0 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 |  | 7290111 | 554803 | SH |  | SOLE |  | 554803 | 0 | 0 |
| CHILDRENS PL INC NEW | COM | 168905107 |  | 252643 | 57030 | SH |  | SOLE |  | 57030 | 0 | 0 |
| CODEXIS INC | COM | 192005106 |  | 9834710 | 4030619 | SH |  | SOLE |  | 4030619 | 0 | 0 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 |  | 11887847 | 1655689 | SH |  | SOLE |  | 1655689 | 0 | 0 |
| COLUMBUS MCKINNON CORP N Y | COM | 199333105 |  | 3109400 | 203628 | SH |  | SOLE |  | 203628 | 0 | 0 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 |  | 11703804 | 4179930 | SH |  | SOLE |  | 4179930 | 0 | 0 |
| CONTEXT THERAPEUTICS INC | COM | 21077P108 |  | 1268129 | 1935484 | SH |  | SOLE |  | 1935484 | 0 | 0 |
| DARIOHEALTH CORP | COM NEW | 23725P209 |  | 1133843 | 1692303 | SH |  | SOLE |  | 1692303 | 0 | 0 |
| DESTINATION XL GROUP INC | COM | 25065K104 |  | 2860219 | 2576774 | SH |  | SOLE |  | 2576774 | 0 | 0 |
| DHI GROUP INC | COM | 23331S100 |  | 7050860 | 2374027 | SH |  | SOLE |  | 2374027 | 0 | 0 |
| DICKS SPORTING GOODS INC | COM | 253393102 |  | 7912400 | 40000 | SH |  | SOLE |  | 40000 | 0 | 0 |
| DISC MEDICINE INC | COM | 254604101 |  | 15241888 | 287800 | SH |  | SOLE |  | 287800 | 0 | 0 |
| DISTRIBUTION SOLUTIONS GRP I | COM | 520776105 |  | 5790676 | 210800 | SH |  | SOLE |  | 210800 | 0 | 0 |
| DYNE THERAPEUTICS INC | COM | 26818M108 |  | 7092990 | 745062 | SH |  | SOLE |  | 745062 | 0 | 0 |
| EDESA BIOTECH INC | COM NEW | 27966L306 |  | 1268750 | 625000 | SH |  | SOLE |  | 625000 | 0 | 0 |
| EHEALTH INC | COM | 28238P109 |  | 5704768 | 1311441 | SH |  | SOLE |  | 1311441 | 0 | 0 |
| ELEDON PHARMACEUTICALS INC | COM | 28617K101 |  | 3092752 | 1141237 | SH |  | SOLE |  | 1141237 | 0 | 0 |
| ELUTIA INC | CL A COM | 05479K106 |  | 6306195 | 3184947 | SH |  | SOLE |  | 3184947 | 0 | 0 |
| ENVVENO MEDICAL CORPORATION | COM | 29415J106 |  | 2372697 | 594661 | SH |  | SOLE |  | 594661 | 0 | 0 |
| ESTABLISHMENT LABS HLDGS INC | COM | G31249108 |  | 75832886 | 1775530 | SH |  | SOLE |  | 1775530 | 0 | 0 |
| ETON PHARMACEUTICALS INC | COM | 29772L108 |  | 16757302 | 1175951 | SH |  | SOLE |  | 1175951 | 0 | 0 |
| EVENTBRITE INC | COM CL A | 29975E109 |  | 16783069 | 6381395 | SH |  | SOLE |  | 6381395 | 0 | 0 |
| EVOKE PHARMA INC | COM | 30049G302 |  | 385198 | 148153 | SH |  | SOLE |  | 148153 | 0 | 0 |
| EVOLUS INC | COM | 30052C107 |  | 38662898 | 4197926 | SH |  | SOLE |  | 4197926 | 0 | 0 |
| EVOLUS INC | COM | 30052C107 |  | 921000 | 100000 | SH | Call | SOLE |  | 100000 | 0 | 0 |
| EXAGEN INC | COM | 30068X103 |  | 427078 | 61186 | SH |  | SOLE |  | 61186 | 0 | 0 |
| EYEPOINT PHARMACEUTICALS INC | COM NEW | 30233G209 |  | 5580986 | 593091 | SH |  | SOLE |  | 593091 | 0 | 0 |
| FORTRESS BIOTECH INC | COM NEW | 34960Q307 |  | 605467 | 325520 | SH |  | SOLE |  | 325520 | 0 | 0 |
| FOSSIL GROUP INC | COM | 34988V106 |  | 7529948 | 5087803 | SH |  | SOLE |  | 5087803 | 0 | 0 |
| FOX FACTORY HLDG CORP | COM | 35138V102 |  | 18901129 | 728648 | SH |  | SOLE |  | 728648 | 0 | 0 |
| FULCRUM THERAPEUTICS INC | COM | 359616109 |  | 29503497 | 4288299 | SH |  | SOLE |  | 4288299 | 0 | 0 |
| GAIA INC NEW | CL A | 36269P104 |  | 4015173 | 914618 | SH |  | SOLE |  | 914618 | 0 | 0 |
| GLOBUS MED INC | CL A | 379577208 |  | 17706000 | 300000 | SH | Call | SOLE |  | 300000 | 0 | 0 |
| GOGO INC | COM | 38046C109 |  | 15332012 | 1044415 | SH |  | SOLE |  | 1044415 | 0 | 0 |
| GRACE THERAPEUTICS INC | COM | 00439U104 |  | 3499263 | 1178203 | SH |  | SOLE |  | 1178203 | 0 | 0 |
| GUARDFORCE AI CO LTD | *W EXP 10/01/202 | G4236L120 |  | 37703 | 154205 | SH |  | SOLE |  | 154205 | 0 | 0 |
| HAIN CELESTIAL GROUP INC | COM | 405217100 |  | 4560000 | 3000000 | SH |  | SOLE |  | 3000000 | 0 | 0 |
| HERBALIFE LTD | COM SHS | G4412G101 |  | 7088209 | 822298 | SH |  | SOLE |  | 822298 | 0 | 0 |
| HERBALIFE LTD | COM SHS | G4412G101 |  | 54306000 | 6300000 | SH | Call | SOLE |  | 6300000 | 0 | 0 |
| HILTON GRAND VACATIONS INC | COM | 43283X105 |  | 82597273 | 1988858 | SH |  | SOLE |  | 1988858 | 0 | 0 |
| HILTON GRAND VACATIONS INC | COM | 43283X105 |  | 23879750 | 575000 | SH | Call | SOLE |  | 575000 | 0 | 0 |
| IMAX CORP | COM | 45245E109 |  | 31706444 | 1133993 | SH |  | SOLE |  | 1133993 | 0 | 0 |
| IMMATICS N.V | *W EXP 07/01/202 | N44445117 |  | 149 | 248506 | SH |  | SOLE |  | 248506 | 0 | 0 |
| INDUSTRIAL LOGISTICS PPTYS T | COM SHS BEN INT | 456237106 |  | 14588296 | 3206219 | SH |  | SOLE |  | 3206219 | 0 | 0 |
| INHIBIKASE THERAPEUTICS INC | COM NEW | 45719W205 |  | 4270500 | 2190000 | SH |  | SOLE |  | 2190000 | 0 | 0 |
| INSPIREMD INC | COM | 45779A846 |  | 5261899 | 2318017 | SH |  | SOLE |  | 2318017 | 0 | 0 |
| ISHARES TR | RUSSELL 2000 ETF | 464287655 |  | 776844000 | 3600000 | SH | Put | SOLE |  | 3600000 | 0 | 0 |
| ITEOS THERAPEUTICS INC | COM | 46565G104 |  | 5948760 | 596666 | SH |  | SOLE |  | 596666 | 0 | 0 |
| JACK IN THE BOX INC | COM | 466367109 |  | 10476000 | 600000 | SH |  | SOLE |  | 600000 | 0 | 0 |
| JEFFERSON CAPITAL INC | COM | 47248R103 |  | 11070000 | 600000 | SH |  | SOLE |  | 600000 | 0 | 0 |
| KEROS THERAPEUTICS INC | COM | 492327101 |  | 21636238 | 1620692 | SH |  | SOLE |  | 1620692 | 0 | 0 |
| KEROS THERAPEUTICS INC | COM | 492327101 |  | 3337500 | 250000 | SH | Call | SOLE |  | 250000 | 0 | 0 |
| KIORA PHARMACEUTICALS INC | COM | 49721T507 |  | 607997 | 211110 | SH |  | SOLE |  | 211110 | 0 | 0 |
| KODIAK SCIENCES INC | COM | 50015M109 |  | 2203997 | 590884 | SH |  | SOLE |  | 590884 | 0 | 0 |
| KOSMOS ENERGY LTD | COM | 500688106 |  | 2952540 | 1716593 | SH |  | SOLE |  | 1716593 | 0 | 0 |
| KRYSTAL BIOTECH INC | COM | 501147102 |  | 27492000 | 200000 | SH | Put | SOLE |  | 200000 | 0 | 0 |
| LADDER CAP CORP | CL A | 505743104 |  | 273061 | 25401 | SH |  | SOLE |  | 25401 | 0 | 0 |
| LIVE NATION ENTERTAINMENT IN | COM | 538034109 |  | 19711784 | 130300 | SH | Put | SOLE |  | 130300 | 0 | 0 |
| LUCID DIAGNOSTICS INC | COM | 54948X109 |  | 108722 | 94541 | SH |  | SOLE |  | 94541 | 0 | 0 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 |  | 4789376 | 353982 | SH |  | SOLE |  | 353982 | 0 | 0 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 |  | 18340224 | 709761 | SH |  | SOLE |  | 709761 | 0 | 0 |
| NEUROPACE INC | COM | 641288105 |  | 3287291 | 295089 | SH |  | SOLE |  | 295089 | 0 | 0 |
| NN INC | COM | 629337106 |  | 5126974 | 2441416 | SH |  | SOLE |  | 2441416 | 0 | 0 |
| NOODLES  CO | COM CL A | 65540B105 |  | 3211513 | 4505489 | SH |  | SOLE |  | 4505489 | 0 | 0 |
| OLAPLEX HLDGS INC | COM | 679369108 |  | 910000 | 650000 | SH |  | SOLE |  | 650000 | 0 | 0 |
| ONKURE THERAPEUTICS INC | COM CL A | 68277Q105 |  | 129557 | 54208 | SH |  | SOLE |  | 54208 | 0 | 0 |
| OPUS GENETICS INC | COM | 67577R102 |  | 3152194 | 3345923 | SH |  | SOLE |  | 3345923 | 0 | 0 |
| PALVELLA THERAPEUTICS INC NE | COM | 697947109 |  | 5636397 | 250062 | SH |  | SOLE |  | 250062 | 0 | 0 |
| PATHWARD FINANCIAL INC | COM | 59100U108 |  | 659940 | 8341 | SH |  | SOLE |  | 8341 | 0 | 0 |
| PAYONEER GLOBAL INC | COM | 70451X104 |  | 3314277 | 483836 | SH |  | SOLE |  | 483836 | 0 | 0 |
| PELOTON INTERACTIVE INC | CL A COM | 70614W100 |  | 22678095 | 3267737 | SH |  | SOLE |  | 3267737 | 0 | 0 |
| PELOTON INTERACTIVE INC | CL A COM | 70614W100 |  | 20820000 | 3000000 | SH | Call | SOLE |  | 3000000 | 0 | 0 |
| PERFECT CORP | *W EXP 99/99/999 | G7006A117 |  | 660 | 16075 | SH |  | SOLE |  | 16075 | 0 | 0 |
| PERFECT CORP | CL A ORD SHS | G7006A109 |  | 1343028 | 583925 | SH |  | SOLE |  | 583925 | 0 | 0 |
| QUINCE THERAPEUTICS INC | COM | 22053A107 |  | 4171698 | 2528302 | SH |  | SOLE |  | 2528302 | 0 | 0 |
| RAPT THERAPEUTICS INC | COM NEW | 75382E208 |  | 7612904 | 951613 | SH |  | SOLE |  | 951613 | 0 | 0 |
| READING INTL INC | CL A | 755408101 |  | 2574258 | 1921088 | SH |  | SOLE |  | 1921088 | 0 | 0 |
| RED VIOLET INC | COM | 75704L104 |  | 9561479 | 194339 | SH |  | SOLE |  | 194339 | 0 | 0 |
| RESERVOIR MEDIA INC | COM | 76119X105 |  | 11061183 | 1442136 | SH |  | SOLE |  | 1442136 | 0 | 0 |
| REZOLUTE INC | COM NEW | 76200L309 |  | 10219622 | 2291395 | SH |  | SOLE |  | 2291395 | 0 | 0 |
| RH | COM | 74967X103 |  | 9450500 | 50000 | SH | Call | SOLE |  | 50000 | 0 | 0 |
| RMR GROUP INC | CL A | 74967R106 |  | 18768198 | 1147902 | SH |  | SOLE |  | 1147902 | 0 | 0 |
| RUMBLEON INC | COM CL B | 781386305 |  | 7560272 | 3272845 | SH |  | SOLE |  | 3272845 | 0 | 0 |
| RUMBLEON INC | COM CL B | 781386305 |  | 3927000 | 1700000 | SH | Call | SOLE |  | 1700000 | 0 | 0 |
| SAVARA INC | COM | 805111101 |  | 18981855 | 8325375 | SH |  | SOLE |  | 8325375 | 0 | 0 |
| SCPHARMACEUTICALS INC | COM | 810648105 |  | 3792619 | 995438 | SH |  | SOLE |  | 995438 | 0 | 0 |
| SCULLY ROYALTY LTD | COM SHS | G7T96K107 |  | 2135456 | 368182 | SH |  | SOLE |  | 368182 | 0 | 0 |
| SENTI BIOSCIENCES INC | COM NEW | 81726A209 |  | 1873680 | 888000 | SH |  | SOLE |  | 888000 | 0 | 0 |
| SERVICE PPTYS TR | COM SH BEN INT | 81761L102 |  | 19258350 | 8057887 | SH |  | SOLE |  | 8057887 | 0 | 0 |
| SILENCE THERAPEUTICS PLC | ADS | 82686Q101 |  | 6046077 | 1042427 | SH |  | SOLE |  | 1042427 | 0 | 0 |
| SOLENO THERAPEUTICS INC | COM | 834203309 |  | 83893103 | 1001350 | SH |  | SOLE |  | 1001350 | 0 | 0 |
| SOLID BIOSCIENCES INC | COM NEW | 83422E204 |  | 8295246 | 1703336 | SH |  | SOLE |  | 1703336 | 0 | 0 |
| SPAR GROUP INC | COM | 784933103 |  | 634260 | 660688 | SH |  | SOLE |  | 660688 | 0 | 0 |
| SPDR SERIES TRUST | S BIOTECH | 78464A870 |  | 66344000 | 800000 | SH | Put | SOLE |  | 800000 | 0 | 0 |
| STRATA SKIN SCIENCES INC | COM | 86272A305 |  | 924970 | 403917 | SH |  | SOLE |  | 403917 | 0 | 0 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 |  | 3495789 | 168553 | SH |  | SOLE |  | 168553 | 0 | 0 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 |  | 3111000 | 150000 | SH | Call | SOLE |  | 150000 | 0 | 0 |
| SURROZEN INC | COM NEW | 86889P208 |  | 2051971 | 229527 | SH |  | SOLE |  | 229527 | 0 | 0 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 |  | 7065921 | 754503 | SH |  | SOLE |  | 754503 | 0 | 0 |
| TALPHERA INC | COM NEW | 00444T209 |  | 916957 | 1992519 | SH |  | SOLE |  | 1992519 | 0 | 0 |
| TANGO THERAPEUTICS INC | COM | 87583X109 |  | 17610721 | 3439594 | SH |  | SOLE |  | 3439594 | 0 | 0 |
| TELA BIO INC | COM | 872381108 |  | 9916481 | 5111588 | SH |  | SOLE |  | 5111588 | 0 | 0 |
| TELA BIO INC | COM | 872381108 |  | 1455000 | 750000 | SH | Call | SOLE |  | 750000 | 0 | 0 |
| TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | 881624209 |  | 16760000 | 1000000 | SH | Call | SOLE |  | 1000000 | 0 | 0 |
| THE ONE GROUP HOSPITALITY IN | COM | 88338K103 |  | 8590390 | 2121084 | SH |  | SOLE |  | 2121084 | 0 | 0 |
| THERATECHNOLOGIES INC | COM NEW | 88338H704 |  | 5717249 | 2422563 | SH |  | SOLE |  | 2422563 | 0 | 0 |
| THIRD HARMONIC BIO INC | COM | 88427A107 |  | 15957141 | 2938700 | SH |  | SOLE |  | 2938700 | 0 | 0 |
| TITAN MACHY INC | COM | 88830R101 |  | 22495285 | 1135552 | SH |  | SOLE |  | 1135552 | 0 | 0 |
| TOURMALINE BIO INC | COM | 89157D105 |  | 8925410 | 558187 | SH |  | SOLE |  | 558187 | 0 | 0 |
| TRANSACT TECHNOLOGIES INC | COM | 892918103 |  | 55068 | 15046 | SH |  | SOLE |  | 15046 | 0 | 0 |
| TRISALUS LIFE SCIENCES INC | COM | 89680M101 |  | 10900000 | 2000000 | SH |  | SOLE |  | 2000000 | 0 | 0 |
| UNICYCIVE THERAPEUTICS INC | COM NEW | 90466Y202 |  | 4559826 | 939202 | SH |  | SOLE |  | 939202 | 0 | 0 |
| UNIQURE NV | SHS | N90064101 |  | 28602817 | 2051852 | SH |  | SOLE |  | 2051852 | 0 | 0 |
| UPSTREAM BIO INC | COM | 91678A107 |  | 6532782 | 594971 | SH |  | SOLE |  | 594971 | 0 | 0 |
| UROGEN PHARMA LTD | COM | M96088105 |  | 91831 | 6703 | SH |  | SOLE |  | 6703 | 0 | 0 |
| UROGEN PHARMA LTD | COM | M96088105 |  | 13700000 | 1000000 | SH | Call | SOLE |  | 1000000 | 0 | 0 |
| VERASTEM INC | COM NEW | 92337C203 |  | 12262150 | 2954735 | SH |  | SOLE |  | 2954735 | 0 | 0 |
| VERVE THERAPEUTICS INC | COM | 92539P101 |  | 3722038 | 331437 | SH |  | SOLE |  | 331437 | 0 | 0 |
| VIATRIS INC | COM | 92556V106 |  | 44650000 | 5000000 | SH | Call | SOLE |  | 5000000 | 0 | 0 |
| VIEMED HEALTHCARE INC | COM | 92663R105 |  | 6443195 | 932445 | SH |  | SOLE |  | 932445 | 0 | 0 |
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 |  | 3956984 | 1978492 | SH |  | SOLE |  | 1978492 | 0 | 0 |
| XENCOR INC | COM | 98401F105 |  | 6446010 | 820103 | SH |  | SOLE |  | 820103 | 0 | 0 |
| XTANT MED HLDGS INC | COM NEW | 98420P308 |  | 50543166 | 68394000 | SH |  | SOLE |  | 68394000 | 0 | 0 |
| Y-MABS THERAPEUTICS INC | COM | 984241109 |  | 1586970 | 351878 | SH |  | SOLE |  | 351878 | 0 | 0 |
| ZEVRA THERAPEUTICS INC | COM NEW | 488445206 |  | 12967756 | 1471936 | SH |  | SOLE |  | 1471936 | 0 | 0 |

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