# EDGAR Filing Document

**Accession Number:** 0001175680
**File Stem:** 0001104659-26-040687
**Filing Date:** 2026-4
**Character Count:** 142897
**Document Hash:** d0362eb584894d39f8a8129f34d9ebfe
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-26-040687.hdr.sgml**: 20260408

**ACCESSION NUMBER**: 0001104659-26-040687

**CONFORMED SUBMISSION TYPE**: 10-Q

**PUBLIC DOCUMENT COUNT**: 69

**CONFORMED PERIOD OF REPORT**: 20260228

**FILED AS OF DATE**: 20260408

**DATE AS OF CHANGE**: 20260408

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** CytoDyn Inc.
- **CENTRAL INDEX KEY:** 0001175680
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 753056237
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0531

**FILING VALUES:**
- **FORM TYPE:** 10-Q
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-49908
- **FILM NUMBER:** 26846579

**BUSINESS ADDRESS:**
- **STREET 1:** 1111 MAIN STREET, SUITE 660
- **CITY:** VANCOUVER
- **STATE:** WA
- **ZIP:** 98660
- **BUSINESS PHONE:** 360-980-8524

**MAIL ADDRESS:**
- **STREET 1:** 1111 MAIN STREET, SUITE 660
- **CITY:** VANCOUVER
- **STATE:** WA
- **ZIP:** 98660

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CYTODYN INC
- **DATE OF NAME CHANGE:** 20031114

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** REXRAY CORP
- **DATE OF NAME CHANGE:** 20020617

?xml version='1.0' encoding='ASCII'? CYTODYN INC._February 28, 2026

[**Table of Contents**](#TOC)

------

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, DC 20549**

**FORM 10-Q**

&nbsp;&nbsp;&nbsp;&nbsp;☒ **QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934** 

**For the quarterly period ended February 28, 2026**

☐ **TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES ACT OF 1933**

**For the transition period from &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; to &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;** 

**Commission File Number: 000-49908**

## CYTODYN INC.
**(Exact name of registrant as specified in its charter)**

---

| | |
|:---|:---|
| **Delaware** | **83-1887078** |
| (State or other jurisdiction of<br>incorporation or organization) | (I.R.S. Employer or<br>Identification No.) |
| **1111 Main Street, Suite 660**<br>**Vancouver, Washington** | **98660** |
| (Address of principal executive offices) | (Zip Code) |

---

**(360) 980-8524**

(Registrant's telephone number, including area code)

**Not applicable**

(Former name, former address and former fiscal year, if changed since last report)

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| ('Unnamed: 0_level_0', 'Title of Each Class <br>') | ('&nbsp;&nbsp;', '&nbsp;&nbsp;&nbsp;Trading<br>Symbol(s)<br>') | ('&nbsp;&nbsp;', '&nbsp;&nbsp;&nbsp;Name of Each Exchange<br>on Which Registered<br>') |
| **None** | **None** | **None** |

---

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒&nbsp;&nbsp;&nbsp;&nbsp;No ☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (Section 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒&nbsp;&nbsp;&nbsp;&nbsp;No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

---

| | | | |
|:---|:---|:---|:---|
| Large Accelerated Filer | ☐ | Accelerated Filer | ☐ |
| Non-accelerated Filer | ☒ | Smaller Reporting Company | ☒ |
|  |  | Emerging Growth Company | ☐ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act):&nbsp;&nbsp;&nbsp;&nbsp;Yes ☐&nbsp;&nbsp;&nbsp;&nbsp;No ☒

On March 31, 2026, there were 1,366,030 thousand shares outstanding of the registrant's $0.001 par value common stock.

------

[**Table of Contents**](#TOC)

**TABLE OF CONTENTS**

---

| | | |
|:---|:---|:---|
| ('Unnamed: 0_level_0', 'Unnamed: 0_level_1') | ('<br>', 'Unnamed: 1_level_1') | ('Unnamed: 2_level_0', '**PAGE**<br>') |
| [PART I](#PARTIFinancialInformation_904720) Financial Information | [PART I](#PARTIFinancialInformation_904720) Financial Information | 3 |
|  | [ITEM 1. CONSOLIDATED FINANCIAL STATEMENTS](#Item1ConsolidatedFinancialStatements_616) | 3 |
|  | [ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS](#Item2ManagementsDiscussionandAnalysisofF) | 23 |
|  | [ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK](#Item3QuantitativeandQualitativeDisclosur) | 31 |
|  | [ITEM 4. CONTROLS AND PROCEDURES](#Item4ControlsandProcedures_512111) | 31 |
| [PART II](#PARTII) Other Information | [PART II](#PARTII) Other Information | 32 |
|  | [ITEM 1. LEGAL PROCEEDINGS](#Item1LegalProceedings_843679) | 32 |
|  | [ITEM 1A. RISK FACTORS](#Item1ARiskFactors) | 32 |
|  | [ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS](#Item2UnregisteredSalesofEquitySecurities) | 32 |
|  | [ITEM 6. EXHIBITS](#Item6Exhibits_430268) | 33 |

---

[**Table of Contents**](#TOC)

**PART I. Financial Information**

#### Item 1. Consolidated Financial Statements
**CytoDyn Inc.**

**Consolidated Balance Sheets**

(Unaudited, in thousands, except par value)

---

| | | |
|:---|:---|:---|
|  | **February 28, 2026** | **May 31, 2025** |
| **Assets** |  |  |
| Current assets: |  |  |
| &nbsp;&nbsp;Cash and cash equivalents | $15655 | $11903 |
| &nbsp;&nbsp;Prepaid expenses | 448 | 252 |
| &nbsp;&nbsp;Prepaid service fees | 2335 | 3723 |
| &nbsp;&nbsp;Other receivables |  | 2000 |
| Total current assets | 18438 | 17878 |
| Other non-current assets | 59 | 169 |
| Total assets | $18497 | $18047 |
| **Liabilities and Stockholders' Deficit** |  |  |
| Current liabilities: |  |  |
| &nbsp;&nbsp;Accounts payable | $13478 | $14692 |
| &nbsp;&nbsp;Accrued liabilities and compensation | 15825 | 2206 |
| &nbsp;&nbsp;Accrued interest on convertible notes | 11750 | 18151 |
| &nbsp;&nbsp;Accrued dividends on convertible preferred stock | 9375 | 8269 |
| &nbsp;&nbsp;Convertible notes payable, net |  | 27200 |
| Total current liabilities | 50428 | 70518 |
| Convertible notes payable, net | 27200 |  |
| Accrued interest on convertible notes | 1585 |  |
| Other liabilities (Note 10) | 43571 | 43571 |
| Total liabilities | 122784 | 114089 |
| Commitments and Contingencies (Note 10) |  |  |
| Stockholders' deficit: |  |  |
| Preferred stock, $0.001 par value; 5,000 shares authorized: |  |  |
| &nbsp;&nbsp;Series B convertible preferred stock, $0.001 par value; 400 authorized; 19 issued and outstanding at February 28, 2026 and May 31, 2025 |  |  |
| &nbsp;&nbsp;Series C convertible preferred stock, $0.001 par value; 8 authorized; 6 issued and outstanding at February 28, 2026 and May 31, 2025 |  |  |
| &nbsp;&nbsp;Series D convertible preferred stock, $0.001 par value; 12 authorized; 9 issued and outstanding at February 28, 2026 and May 31, 2025 |  |  |
| Common stock, $0.001 par value; 2,250,000 shares authorized; 1,358,242 and 1,249,460 issued, and 1,357,956 and 1,249,174 outstanding at February 28, 2026 and May 31, 2025, respectively | 1358 | 1249 |
| Treasury stock, $0.001 par value; 286 shares at February 28, 2026 and May 31, 2025 |  |  |
| Additional paid-in capital | 814978 | 790495 |
| Accumulated deficit | (920623) | (887786) |
| Total stockholders' deficit | (104287) | (96042) |
| Total liabilities and stockholders' deficit | $18497 | $18047 |

---

See accompanying notes to consolidated financial statements.

[**Table of Contents**](#TOC)

**CytoDyn Inc.**

**Consolidated Statements of Operations**

(Unaudited, in thousands, except per share data)

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Nine months ended February 28,** | **Nine months ended February 28,** |
|  | **2026** | **2025** | **2026** | **2025** |
| Operating expenses: |  |  |  |  |
| &nbsp;&nbsp;General and administrative | $1654 | $1516 | $5166 | $5423 |
| &nbsp;&nbsp;Research and development | 4649 | 2487 | 11183 | (20150) |
| &nbsp;&nbsp;Legal settlement loss |  |  | 16587 |  |
| Total operating expenses | 6303 | 4003 | 32936 | (14727) |
| Operating (loss) gain  | (6303) | (4003) | (32936) | 14727 |
| Interest and other income (expense): |  |  |  |  |
| &nbsp;&nbsp;Interest income | 15 | 173 | 166 | 441 |
| &nbsp;&nbsp;Interest on convertible notes | (614) | (1143) | (1934) | (3469) |
| &nbsp;&nbsp;Amortization of discount on convertible notes |  | (110) |  | (348) |
| &nbsp;&nbsp;Standby equity purchase agreement commitment fee |  |  | (325) |  |
| &nbsp;&nbsp;Issuance costs for private placement of shares and warrants through placement agent (Note 5) | (1628) |  | (1628) |  |
| &nbsp;&nbsp;Legal settlement revaluation | 3842 |  | 3842 |  |
| &nbsp;&nbsp;Loss on induced conversion |  |  |  | (1180) |
| &nbsp;&nbsp;Finance charges | (2) | (2) | (22) | (25) |
| &nbsp;&nbsp;Gain on restructuring of payables |  | 327 |  | 407 |
| &nbsp;&nbsp;Loss on derivatives |  |  |  | (852) |
| Total interest and other expenses | 1613 | (755) | 99 | (5026) |
| (Loss) gain before income taxes | (4690) | (4758) | (32837) | 9701 |
| Income tax benefit |  |  |  |  |
| Net (loss) income | $(4690) | $(4758) | $(32837) | $9701 |
| (Loss) income per share: |  |  |  |  |
| &nbsp;&nbsp;Basic | $(0.00) | $(0.00) | $(0.03) | $0.01 |
| &nbsp;&nbsp;Diluted | $(0.00) | $(0.00) | $(0.03) | $0.01 |
| Weighted average common shares used in calculation of (loss) income per share: |  |  |  |  |
| &nbsp;&nbsp;Basic | 1275184 | 1228259 | 1262834 | 1194561 |
| &nbsp;&nbsp;Diluted | 1275184 | 1228259 | 1262834 | 1225538 |

---

See accompanying notes to consolidated financial statements.

[**Table of Contents**](#TOC)

**CytoDyn Inc.**

**Consolidated Statement of Changes in Stockholders' Deficit**

(Unaudited, in thousands)

---

| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
|  | **Preferred stock** | **Preferred stock** | **Common stock** | **Common stock** | **Treasury stock** | **Treasury stock** | | | |
|  | **Shares** | **Amount** | **Shares** | **Amount** | **Shares** | **Amount** | **Additional**<br>**paid-in capital** | **Accumulated**<br>**deficit** | **Total stockholders'**<br>**deficit** |
| Balance at May 31, 2025 | 34 | $— | 1249460 | $1249 | 286 | $— | $790495 | $(887786) | $(96042) |
| &nbsp;&nbsp;&nbsp;Issuance of stock for convertible note repayment  |  |  | 7462 | 8 |  |  | 2242 |  | 2250 |
| &nbsp;&nbsp;&nbsp;Stock option exercises |  |  | 100 |  |  |  | 21 |  | 21 |
| &nbsp;&nbsp;&nbsp;Warrant exercises |  |  | 23 |  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Dividends accrued on Series C and D convertible preferred stock  |  |  |  |  |  |  | (373) |  | (373) |
| &nbsp;&nbsp;&nbsp;Stock-based compensation  |  |  |  |  |  |  | 180 |  | 180 |
| &nbsp;&nbsp;&nbsp;Net loss |  |  |  |  |  |  |  | (5540) | (5540) |
| Balance at August 31, 2025 | 34 | $— | 1257045 | $1257 | 286 | $— | $792565 | $(893326) | $(99504) |
| &nbsp;&nbsp;&nbsp;Issuance of stock for convertible note repayment  |  |  | 8060 | 8 |  |  | 2242 |  | 2250 |
| &nbsp;&nbsp;&nbsp;Warrant exercises |  |  | 399 |  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Standby equity purchase agreement commitment fee |  |  | 635 | 1 |  |  | 299 |  | 300 |
| &nbsp;&nbsp;&nbsp;Dividends accrued on Series C and D convertible preferred stock  |  |  |  |  |  |  | (369) |  | (369) |
| &nbsp;&nbsp;&nbsp;Stock-based compensation  |  |  |  |  |  |  | 183 |  | 183 |
| &nbsp;&nbsp;&nbsp;Net loss |  |  |  |  |  |  |  | (22607) | (22607) |
| Balance at November 30, 2025 | 34 |  | 1266139 | 1266 | 286 |  | 794920 | (915933) | (119747) |
| &nbsp;&nbsp;&nbsp;Issuance of stock for convertible note repayment  |  |  | 8562 | 9 |  |  | 2241 |  | 2250 |
| &nbsp;&nbsp;&nbsp;Stock issued for private offerings |  |  | 80341 | 80 |  |  | 19941 |  | 20021 |
| &nbsp;&nbsp;&nbsp;Issuance costs related to stock to be issued for private offerings |  |  |  |  |  |  | (3075) |  | (3075) |
| &nbsp;&nbsp;&nbsp;Standby equity purchase agreement advance notices |  |  | 3200 | 3 |  |  | 871 |  | 874 |
| &nbsp;&nbsp;&nbsp;Dividends accrued on Series C and D preferred stock  |  |  |  |  |  |  | (364) |  | (364) |
| &nbsp;&nbsp;&nbsp;Stock-based compensation  |  |  |  |  |  |  | 444 |  | 444 |
| &nbsp;&nbsp;&nbsp;Net loss |  |  |  |  |  |  |  | (4690) | (4690) |
| &nbsp;&nbsp;&nbsp;Balance at February 28, 2026 | 34 | $— | 1358242 | $1358 | 286 | $— | $814978 | $(920623) | $(104287) |

---

See accompanying notes to consolidated financial statements.

[**Table of Contents**](#TOC)

**CytoDyn Inc.**

**Consolidated Statement of Changes in Stockholders' Deficit**

(Unaudited, in thousands)

---

| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
|  | **Preferred stock** | **Preferred stock** | **Common stock** | **Common stock** | **Treasury stock** | **Treasury stock** | | | |
|  | **Shares** | **Amount** | **Shares** | **Amount** | **Shares** | **Amount** | **Additional**<br>**paid-in capital**  | **Accumulated**<br>**deficit** | **Total stockholders'**<br>**deficit** |
| Balance at May 31, 2024  | 34 | $— | 1059002 | $1059 | 443 | $— | $773714 | $(891531) | $(116758) |
| &nbsp;&nbsp;&nbsp;Issuance of stock for convertible note repayment  |  |  | 8777 | 9 |  |  | 991 |  | 1000 |
| &nbsp;&nbsp;&nbsp;Loss on induced conversion |  |  |  |  |  |  | 1180 |  | 1180 |
| &nbsp;&nbsp;&nbsp;Stock issued for tender offer |  |  | 152505 | 152 |  |  | 13874 |  | 14026 |
| &nbsp;&nbsp;&nbsp;Issuance costs related to stock issued for tender offer |  |  |  |  |  |  | (3649) |  | (3649) |
| &nbsp;&nbsp;&nbsp;Dividends accrued on Series C and D convertible preferred stock  |  |  |  |  |  |  | (372) |  | (372) |
| &nbsp;&nbsp;&nbsp;Stock-based compensation  |  |  |  |  |  |  | 136 |  | 136 |
| &nbsp;&nbsp;&nbsp;Net income |  |  |  |  |  |  |  | 19227 | 19227 |
| Balance at August 31, 2024 | 34 | $— | 1220284 | $1220 | 443 | $— | $785874 | $(872304) | $(85210) |
| &nbsp;&nbsp;&nbsp;Issuance of stock for convertible note repayment  |  |  | 3233 | 4 |  |  | 416 |  | 420 |
| &nbsp;&nbsp;&nbsp;Dividends accrued on Series C and D convertible preferred stock  |  |  |  |  |  |  | (369) |  | (369) |
| &nbsp;&nbsp;&nbsp;Stock-based compensation  |  |  |  |  |  |  | 537 |  | 537 |
| &nbsp;&nbsp;&nbsp;Net loss |  |  |  |  |  |  |  | (4768) | (4768) |
| Balance at November 30, 2024 | 34 |  | 1223517 | 1224 | 443 |  | 786458 | (877072) | (89390) |
| &nbsp;&nbsp;&nbsp;Issuance of stock for convertible note repayment  |  |  | 7802 | 8 |  |  | 1165 |  | 1173 |
| &nbsp;&nbsp;&nbsp;Stock option exercises |  |  | 100 |  |  |  | 21 |  | 21 |
| &nbsp;&nbsp;&nbsp;Stock issued for compensation |  |  | 162 |  |  |  | 40 |  | 40 |
| &nbsp;&nbsp;&nbsp;Stock adjustment |  |  | (651) | (1) | (157) |  |  |  | (1) |
| &nbsp;&nbsp;&nbsp;Exercise of warrants, net of issuance costs |  |  | 1661 | 2 |  |  | (1) |  | 1 |
| &nbsp;&nbsp;&nbsp;Dividends accrued on Series C and D convertible preferred stock  |  |  |  |  |  |  | (365) |  | (365) |
| &nbsp;&nbsp;&nbsp;Stock-based compensation  |  |  |  |  |  |  | 300 |  | 300 |
| &nbsp;&nbsp;&nbsp;Net loss |  |  |  |  |  |  |  | (4758) | (4758) |
| Balance at February 28, 2025 | 34 | $— | 1232591 | $1233 | 286 | $— | $787618 | $(881830) | $(92979) |

---

See accompanying notes to consolidated financial statements.

[**Table of Contents**](#TOC)

**CytoDyn Inc.**

**Consolidated Statements of Cash Flows**

(Unaudited, in thousands)

---

| | | |
|:---|:---|:---|
|  | **Nine months ended February 28,** | **Nine months ended February 28,** |
|  | **2026** | **2025** |
| Cash flows from operating activities: |  |  |
| &nbsp;&nbsp;Net (loss) income | $(32837) | $9701 |
| &nbsp;&nbsp;Adjustments to reconcile net (loss) income to net cash used in operating activities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Depreciation | 13 | 14 |
| &nbsp;&nbsp;&nbsp;&nbsp;Standby equity purchase agreement non-cash commitment fee | 300 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Issuance costs for private placement of shares and warrants through placement agent | 1628 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Amortization of discount on convertible notes |  | 348 |
| &nbsp;&nbsp;&nbsp;&nbsp;Gain on restructuring of payables  |  | (407) |
| &nbsp;&nbsp;&nbsp;&nbsp;Loss on derivatives |  | 852 |
| &nbsp;&nbsp;&nbsp;&nbsp;Loss on induced conversion |  | 1180 |
| &nbsp;&nbsp;&nbsp;&nbsp;Stock-based compensation | 807 | 1013 |
| &nbsp;&nbsp;&nbsp;&nbsp;Changes in operating assets and liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Prepaid expenses and other assets | 3289 | (3483) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accounts payable, accrued expenses, and other liabilities | 14481 | (12320) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash used in operating activities | (12319) | (3102) |
| Cash flows from investing activities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash provided by/used in investing activities |  |  |
| Cash flows from financing activities: |  |  |
| &nbsp;&nbsp;Proceeds from warrant transactions, net of offering costs |  | 10377 |
| &nbsp;&nbsp;Proceeds from sale of common stock and warrants, net of issuance costs | 15318 |  |
| &nbsp;&nbsp;Proceeds from standby equity purchase agreement, net of issuance costs | 874 |  |
| &nbsp;&nbsp;Proceeds from exercise of stock options | 21 | 21 |
| &nbsp;&nbsp;Cash paid for note payable | (142) | (710) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash provided by financing activities | 16071 | 9688 |
| Net change in cash and cash equivalents | 3752 | 6586 |
| Cash and cash equivalents at beginning of period | 11903 | 9814 |
| Cash and cash equivalents at end of period | $15655 | $16400 |
| Supplemental disclosure: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Cash paid for interest | $20 | $25 |
| Non-cash investing and financing transactions: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Issuance of common stock for interest on convertible notes | $6750 | $2593 |
| &nbsp;&nbsp;&nbsp;&nbsp;Accrued dividends on Series C and D convertible preferred stock  | $1106 | $1106 |
| &nbsp;&nbsp;&nbsp;&nbsp;Warrants issued to placement agent | $2573 | $— |

---

See accompanying notes to consolidated financial statements.

[**Table of Contents**](#TOC)

**CYTODYN INC.**

#### NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

#### AS OF FEBRUARY 28, 2026
(Unaudited)

#### Note 1. Organization
CytoDyn Inc. (together with its wholly owned subsidiary, the "Company") was originally incorporated under the laws of Colorado on May 2, 2002, under the name RexRay Corporation and, effective August 27, 2015, reincorporated under the laws of Delaware. The Company is a clinical-stage biotechnology company focused on the clinical development of innovative treatments for multiple therapeutic indications based on its product candidate, leronlimab, a novel humanized monoclonal antibody targeting the C-C chemokine receptor type 5 ("CCR5").

The Company investigates leronlimab as a viral entry inhibitor believed to competitively bind to the N-terminus and second extracellular loop of the CCR5 receptor. The CCR5 receptor is believed to be implicated in immune-mediated illnesses. Leronlimab is being studied in solid tumors in oncology. The Company also strategically works with select partners to explore leronlimab's potential benefits in certain inflammatory diseases.

#### Note 2. Summary of Significant Accounting Policies

#### Basis of presentation
The unaudited consolidated financial statements include the accounts of CytoDyn Inc. and its wholly owned subsidiary, CytoDyn Operations Inc. All intercompany transactions and balances are eliminated in consolidation. The consolidated financial statements reflect all normal recurring adjustments which are, in the opinion of management, necessary for a fair statement of the results of operations for the interim financial statements. Certain information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States ("U.S. GAAP" or "GAAP") have been omitted in accordance with the rules and regulations of the United States Securities and Exchange Commission ("SEC"). The interim financial information and notes thereto should be read in conjunction with the Company's latest Annual Report on Form 10-K for the fiscal year ended May 31, 2025 (the "2025 Form 10-K"). The results of operations for the periods presented are not necessarily indicative of results to be expected for the entire fiscal year or for any other future annual or interim period.

#### Going concern
The accompanying consolidated financial statements have been prepared on a going concern basis, which contemplates the realization of assets and satisfaction of liabilities in the normal course of business. As presented in the accompanying consolidated financial statements, the Company had losses for all periods presented, except for the nine months ended February 28, 2025 due to a one-time return of clinical expenses. The Company has an accumulated deficit of approximately $920.6 million as of February 28, 2026. These factors, among others, including the various matters discussed in Note 10, *Commitments and Contingencies*, raise substantial doubt about the Company's ability to continue as a going concern. The consolidated financial statements do not include any adjustments relating to the recoverability of assets and classification of liabilities that might be necessary should the Company be unable to continue as a going concern.

The Company's continuance as a going concern is dependent upon its ability to obtain additional operating capital, complete the development of its product candidate, leronlimab, obtain approval to commercialize leronlimab from regulatory agencies, continue to outsource manufacturing of leronlimab, and ultimately generate revenues and attain profitability. The Company plans to continue to engage in research and development activities related to leronlimab and a new or modified longer-acting therapeutic for multiple indications and expects to incur significant research and development expenses in the future, primarily related to its regulatory compliance, including performing additional pre-clinical and clinical studies in various indications, and seeking regulatory approval for its product candidate for commercialization. These research and development activities are subject to significant risks and uncertainties. The Company intends to finance its future development activities and its working capital needs primarily from the sale of

[**Table of Contents**](#TOC)

equity and debt securities, combined with additional funding from other sources. However, there can be no assurance that the Company will be successful in these endeavors.

#### Use of estimates
The unaudited consolidated financial statements have been prepared in accordance with GAAP, which requires management to make estimates and judgments that affect the reported amounts of assets, liabilities, and the disclosure of contingent assets and liabilities at the date of consolidated financial statements, and the reported amounts of expenses during the reporting period. Estimates are assessed each period and updated to reflect current information, such as the status of our analysis of the results of our clinical trials and discussions with the U.S. Food and Drug Administration ("FDA"), which could have an impact on the Company's significant accounting estimates and assumptions. The Company's estimates are based on historical experience and on various other assumptions that are believed to be reasonable under the circumstances. Significant estimates include, but are not limited to, those relating to stock-based compensation, and the assumptions used to value warrants and warrant modifications. Actual results could differ from these estimates.

*Cash and cash equivalents*

Cash and cash equivalents are short-term, highly liquid investments with original maturities of three months or less when purchased and comprise bank deposits and money market funds. Our investments in money market funds are recorded at fair value. The value of the money market fund as of February 28, 2026, and May 31, 2025, was approximately $2.1 million and $11.4 million, respectively.

*Fair value of financial instruments*

In accordance with the prescribed accounting guidance, the Company measured fair value of money market funds, and common shares related to the Securities Class Action Lawsuits settlement (for further information, see Note 10, *Commitments and Contingencies*) using the fair value hierarchy which include:

Level 1. Quoted prices in active markets for identical assets or liabilities.

---

| | |
|:---|:---|
| Level 2.  | Observable inputs other than Level 1 prices, such as quoted prices for similar assets or liabilities, quoted prices in markets with insufficient volume or infrequent transactions (less active markets), or model-derived valuations in which all significant inputs are observable or can be derived principally from or corroborated with observable market data for substantially the full term of the assets or liabilities. Level 2 inputs also include non-binding market consensus prices that can be corroborated with observable market data, as well as quoted prices that were adjusted for security-specific restrictions.  |

---

---

| | |
|:---|:---|
| Level 3.  | Unobservable inputs to the valuation methodology are significant to the measurement of the fair value of assets or liabilities. These Level 3 inputs also include non-binding market consensus prices or non-binding broker quotes that the Company was unable to corroborate with observable market data. |

---

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*Recent Accounting Pronouncements*

In October 2023, the Financial Accounting Standards Board ("FASB") issued Accounting Standards Update ("ASU") 2023-06, *Disclosure Improvements* – *Codification Amendments in Response to the SEC's Disclosure Update and Simplification Initiative.* The amendments clarify or improve disclosure and presentation requirements on various disclosure areas, including the statement of cash flows, earnings per share, debt, equity, and derivatives. The amendments will align the requirements in the FASB Accounting Standards Codification ("ASC") with the SEC's regulations. The amendments in this ASU will be effective on the date the related disclosures are removed from Regulation S-X or Regulation S-K by the SEC and will not be effective if the SEC has not removed the applicable disclosure requirement by June 30, 2027. Early adoption is prohibited. The Company is currently evaluating the potential impact of this update on its financial statement disclosures.

In December 2023, the FASB issued ASU No. 2023-09, *Improvements to Income Tax Disclosures*, which requires disclosure of disaggregated income taxes paid, prescribes standard categories for the components of the effective tax rate reconciliation, and modifies other income tax-related disclosures. The ASU is effective for annual periods beginning after December 15, 2024, and allows for adoption on a prospective basis, with a retrospective option. The Company is currently evaluating the potential impact of this update on its consolidated financial statements and related disclosures.

In November 2024, the FASB issued ASU 2024-03, *"Income Statement (Topic 220): Reporting Comprehensive Income - Expense Disaggregation Disclosures, Disaggregation of Income Statement Expenses,"* which requires public companies to disclose, in interim and annual reporting periods, additional information about certain expenses in the financial statements. In January 2025, the FASB issued ASU 2025-01, "Income Statement—Reporting Comprehensive Income—Expense Disaggregation Disclosures (Subtopic 220-40) – Clarifying the Effective Date" to clarify the effective date for non-calendar year-end entities. The amendments in this ASU will be effective for annual periods beginning after December 15, 2026, and interim reporting periods within annual reporting periods beginning after December 15, 2027. Early adoption is permitted and is effective on either a prospective basis or retrospective basis. The Company is currently evaluating the potential impact of this update on its consolidated financial statements and related disclosures.

In November 2024, the FASB issued ASU 2024-04, *"Debt—Debt with Conversion and Other Options (Subtopic 470-20): Induced Conversions of Convertible Debt Instruments,"* which clarifies the requirements for determining whether certain settlements of convertible debt instruments should be accounted for as an induced conversion or extinguishment of convertible debt. The new guidance is effective for annual reporting periods beginning after December 15, 2025, and interim periods within those annual periods. The Company is currently evaluating the potential impact of this update on its consolidated financial statements and related disclosures.

#### Note 3. Accrued Liabilities and Compensation
The components of accrued liabilities and compensation are as follows (in thousands):

---

| | | |
|:---|:---|:---|
|  | **February 28, 2026** | **May 31, 2025** |
| Compensation and related expense | $255 | $278 |
| Legal settlement | 12745 |  |
| Legal fees | 15 | 50 |
| Clinical expense | 2213 | 487 |
| License fees | 563 | 1105 |
| Lease payable | 34 | 141 |
| Other liabilities |  | 145 |
| &nbsp;&nbsp;Total accrued liabilities | $15825 | $2206 |

---

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#### Note 4. Convertible Instruments and Accrued Interest
*Convertible preferred stock*

The following table presents the number of potentially issuable shares of common stock, should shares of preferred stock and amounts of undeclared and accrued preferred dividends be converted to common stock. 

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | **February 28, 2026** | **February 28, 2026** | **February 28, 2026** | **May 31, 2025** | **May 31, 2025** | **May 31, 2025** |
| *(in thousands except conversion rate)* | **Series B** | **Series C** | **Series D** | **Series B** | **Series C** | **Series D** |
| Shares of preferred stock outstanding | 19 | 6 | 9 | 19 | 6 | 9 |
| Common stock conversion rate | 10:1 | 2,000:1 | 1,250:1 | 10:1 | 2,000:1 | 1,250:1 |
| Total shares of common stock if converted | 190 | 12670 | 10565 | 190 | 12670 | 10565 |
| Undeclared dividends | $28 | $— | $— | $24 | $— | $— |
| Accrued dividends | $— | $4243 | $5132 | $— | $3769 | $4500 |
| Total shares of common stock if dividends converted | 56 | 8486 | 10264 | 48 | 7538 | 9000 |

---

Under the Company's Amended and Restated Certificate of Incorporation, as amended (the "Certificate of Incorporation"), dividends on its outstanding shares of Series B Convertible Preferred Stock (the "Series B preferred stock") may be paid in cash or shares of the Company's common stock at the election of the Company. Dividends on outstanding shares of Series C Convertible Preferred Stock (the "Series C preferred stock") and Series D Convertible Preferred Stock (the "Series D preferred stock") are payable in cash or shares of common stock at the election of the holder. The preferred stockholders have the right to dividends only when and if declared by the Company's Board of Directors. Under Section 170 of the Delaware General Corporation Law, the Company is permitted to pay dividends only out of capital surplus or, if none, out of net profits for the fiscal year in which the dividend is declared or net profits from the preceding fiscal year.

Series B preferred stock provides for a liquidation preference over the common shares of $5.00 per share, plus any accrued and unpaid dividends. In the event of liquidation, holders of Series C and Series D preferred stock will be entitled to receive, on a pari passu basis, and in preference of any payment or distribution to holders of the Series B preferred stock and common stock, an amount per share equal to $1,000 per share plus any accrued and unpaid dividends.

*Convertible Notes and Accrued Interest*

The table below presents outstanding convertible notes and accrued interest as of February 28, 2026 and May 31, 2025:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | **February 28, 2026** | **February 28, 2026** | **February 28, 2026** | **May 31, 2025** | **May 31, 2025** | **May 31, 2025** |
| *(in thousands)* | **April 2, 2021 Note** | **April 23, 2021 Note** | **Total** | **April 2, 2021 Note** | **April 23, 2021 Note** | **Total** |
| Convertible notes payable outstanding principal | $2831 | $24369 | $27200 | $2831 | $24369 | $27200 |
| Accrued interest on convertible notes | 5755 | 7580 | 13335 | 5378 | 12773 | 18151 |
| Outstanding convertible notes payable, net and accrued interest | $8586 | $31949 | $40535 | $8209 | $37142 | $45351 |

---

Reconciliation of changes to the outstanding balance of convertible notes, including accrued interest, were as follows:

---

| | | | |
|:---|:---|:---|:---|
| *(in thousands)* | **April 2, 2021 Note** | **April 23, 2021 Note** | **Total** |
| Outstanding balance at May 31, 2025 | $8209 | $37142 | $45351 |
| Interest expense | 377 | 1557 | 1934 |
| Fair market value of shares exchanged for repayment |  | (6750) | (6750) |
| Outstanding balance at February 28, 2026 | $8586 | $31949 | $40535 |

---

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*April 2, 2021 & April 23, 2021 Notes*

Key terms of the outstanding convertible notes (the "Notes") are as follows:

---

| | | |
|:---|:---|:---|
|  | **February 28, 2026** | **February 28, 2026** |
|  | **April 2, 2021 Note** | **April 23, 2021 Note** |
| Interest rate per annum | 6% | 6% |
| Conversion price per share upon five trading days' notice | $10.00 | $10.00 |
| Party that controls the conversion rights | Investor | Investor |
| Maturity date | April 5, 2026 | April 23, 2026 |
| Security interest | All Company assets excluding intellectual property | All Company assets excluding intellectual property |

---

In addition to standard anti-dilution adjustments, the conversion price of the Notes is subject to full-ratchet anti-dilution protection, pursuant to which the conversion price will be automatically reduced to equal the effective price per share in any new offering by the Company of equity securities that have registration rights, are registered, or become registered under the Securities Act of 1933, as amended (the "Securities Act"). The Notes provide for liquidated damages upon failure to deliver common stock within specified timeframes and require the Company to maintain a share reservation of 6.0 million shares of common stock for each Note. Subsequent to February 28, 2026, the Company and the noteholders entered into amendments to the existing Note terms, extending the maturity date of each Note by three years and lowering the interest rate of the Notes to 5%. For further information, see Note 12, *Subsequent Events.* 

During the nine months ended February 28, 2026, in satisfaction of the required monthly payments, the Company and April 23, 2021 Noteholder entered into exchange agreements, pursuant to which the April 23, 2021 Note was partitioned into new notes (the "Partitioned Notes") with an aggregate principal amount of approximately $6.8 million, which were exchanged concurrently for shares of the Company's common stock of equal value, amounting to approximately 24.1 million shares of common stock. The monthly payments were applied to accrued interest on the April 23, 2021 Note. The outstanding balance of the April 23, 2021 Note was reduced by the Partitioned Notes to a total amount of $31.9 million.

As of the filing date of this report, the holders of the Notes waived all provisions that, based on the occurrence of various events through that date, could have triggered the imposition of a default interest rate, a downward adjustment of the conversion price, or specified other provisions relating to default, breach or imposition of a penalty. Accordingly, the Company was not in default under the Notes on the filing date of this report.

#### Note 5. Equity
*Standby Equity Purchase Agreement*

On November 3, 2025, the Company entered into a Standby Equity Purchase Agreement (the "Purchase Agreement") with YA II PN, Ltd., a Cayman Islands exempt limited partnership ("Yorkville").

Pursuant to and subject to the terms of the Purchase Agreement, for 36 months following the date of the Purchase Agreement, the Company has the right, but not the obligation, to sell to Yorkville, and Yorkville is obligated to purchase from the Company, shares of the Company's common stock.

At the Company's option, the shares of common stock would be purchased at 98% of the lowest daily volume weighted average price ("VWAP") during the three consecutive trading days (the "Pricing Period") commencing on the date (each, an "Advance Notice Date") the Company is deemed to have delivered a written notice to Yorkville setting forth the number of shares of common stock that the Company desires to issue and sell to Yorkville in accordance with the terms of the Purchase Agreement (each notice, an "Advance Notice"), subject to certain limitations. The Company, at its discretion, may also specify a minimum acceptable price per share in an Advance Notice (each issuance and sale, an "Advance"). While there is no mandatory minimum amount for any Advance, it may not exceed an amount equal to 100% of the average of the daily traded amount on the five consecutive trading days immediately preceding an Advance

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Notice. Further, subject to the above conditions, in no event shall Yorkville be required to purchase more than $30,000,000 of shares of common stock in the aggregate during the term of the Purchase Agreement (the "Commitment Amount").

As consideration for Yorkville's commitment to purchase the common stock pursuant the Purchase Agreement, the Company (i) paid Yorkville a structuring fee in the amount of $25,000; and (ii) will pay a commitment fee in an amount equal to 1.00% of the Commitment Amount (the "Commitment Fee"), to be paid in the form of shares of common stock issued to Yorkville (the "Commitment Shares"), of which one-half was issued on November 3, 2025, and the remaining one-half shall be issued on the six-month anniversary of the Purchase Agreement.

The Purchase Agreement will automatically terminate on the earlier of (i) the 36-month anniversary of the date of the Purchase Agreement, or (ii) the date Yorkville has made full payment of Advances equal to the Commitment Amount. The Company has the right to terminate the Purchase Agreement upon five trading days' prior written notice to Yorkville, subject to certain conditions. The Company and Yorkville may also agree to terminate the Purchase Agreement by mutual written consent.

During the nine months ended February 28, 2026, pursuant to the Purchase Agreement, the Company sold approximately 3.2 million shares of common stock in exchange for approximately $0.9 million in cash.

*Private placement of common stock and warrants through placement agent*

On February 27, 2026, the Company concluded a private offering to accredited investors of units through a placement agent that commenced in January 2026 (the "Placement Agent Offering"). Each unit consists of one share of common stock and one warrant to purchase one share of common stock. The purchase price per unit, $0.2153 (the "deal price"), was equal to 90% of the intraday volume weighted average prices of the common stock as of the initial closing on January 30, 2026. The Company sold approximately 81.3 million units for a total of approximately $17.5 million in cash in the Placement Agent Offering. Of these, approximately $16.3 million of proceeds relating to approximately 75.9 million units had been remitted to the Company by February 28, 2026. The Company classified the securities issued in the private placement as a liability until the final close, when it was reclassified as equity.

The warrants issued to the investors in the private placement have a five-year term and an exercise price of $0.26 per share. The warrants were fully exercisable when issued. Except as described above, the terms of the warrants will be substantially similar to the form of warrant included as Exhibit 4.1 in the Company's Current Report on Form 8-K filed with the SEC on September 7, 2021.

The Company has agreed to use commercially reasonable efforts to prepare and file, and cause the SEC to declare effective, a registration statement under the Securities Act of 1933, as amended (the "Securities Act"), covering the resale of the shares of common stock and the shares to be received upon the exercise of the warrants sold in the private placement.

As compensation to the placement agent, the Company has paid a cash fee equal to 13% of the gross proceeds received from qualified investors. The Company has also issued to the placement agent or its designees warrants to purchase approximately 12.2 million shares of common stock with an exercise price equal to the deal price. Additionally, the placement agent was given the right to exchange warrants to purchase up to 3.0 million shares for newly issued warrants to purchase an equal number of shares, also with an exercise price equal to the deal price. All warrants issued to the placement agent in connection with the private placement include a cashless exercise provision and are exercisable for a period of 10 years from the date of issuance.

Based on contractual payment terms, the private placement transactions above are considered convertible debt instruments prior to final settlement, and the option to enter a final closing that would lower the purchase price is considered a share-settled redemption feature. Therefore, approximately $1.6 million of cash and non-cash issuance costs associated with such issuances were capitalized and subsequently recognized through the statement of operations as interest expense on the final closing date.

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*Direct Private Sales of Common Stock and Warrants to Accredited Investors*

On January 23, 2026, in a private sale by the Company directly to an accredited investor, the Company issued a total of 3,944,773 shares of common stock in exchange for total gross cash proceeds to the Company of approximately $1.0 million. The transaction did not include warrants.

On February 26, 2026, the Company accepted a $100,000 investment from an accredited investor in a transaction not involving a placement agent. The terms of the investment were identical to those of the Placement Agent Offering described above. Based on the deal price of $0.2153 per unit, the accredited investor received 464,468 units.

*Warrants*

Warrant activity is presented in the table below:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  |  |  | **Weighted**  |  |
|  |  |  | **average** |  |
|  |  | **Weighted** | **remaining** | **Aggregate** |
|  | **Number of** | **average** | **contractual** | **intrinsic** |
| *(in thousands, except for share data and years)* | **shares** | **exercise price** | **life in years** | **value** |
| Warrants outstanding at May 31, 2025 | 213128 | $0.27 | 3.71 | $27923 |
| Granted | 87786 | $0.25 |  |  |
| Exercised | (597) | $0.09 |  | 129 |
| Forfeited, expired, and cancelled | (105) | $3.07 |  |  |
| Warrants outstanding at February 28, 2026 | 300212 | $0.26 | 3.75 | $13391 |
| Warrants outstanding and exercisable at February 28, 2026 | 300212 | $0.26 | 3.75 | $13391 |

---

*Warrant exercises*

During the nine months ended February 28, 2026, the Company issued approximately 0.4 million shares of common stock in connection with the cashless exercise of approximately 0.6 million warrants with stated exercise prices of $0.09387 per share.

**Note 6. Equity Incentive Plan**

*Equity Incentive Plan*

As of February 28, 2026, the Company had one active equity incentive plan, the *CytoDyn Inc. Amended and Restated 2012 Equity Incentive Plan* (the "EIP"). As of February 28, 2026 and May 31, 2025, the EIP covered a total of 79.3 million and 66.8 million shares of common stock, respectively. The "evergreen provision" automatically increased the number of shares of common stock subject to the EIP by an amount equal to 1% of the total outstanding shares on June 1, 2025. The EIP provides for awards of stock options to purchase shares of common stock, restricted and unrestricted shares of common stock, restricted stock units ("RSUs"), and performance share units ("PSUs").

The Company recognizes the compensation cost of employee and director services received in exchange for equity awards based on the grant date estimated fair value of the awards. Share-based compensation cost is recognized over the period during which the employee or director is required to provide services in exchange for the award and, as forfeitures occur, the associated compensation cost recognized to date is reversed. For awards with performance-based payout conditions, the Company recognizes compensation cost based on the probability of achieving the performance conditions, with changes in expectations recognized as an adjustment to earnings in the period of change. Any recognized compensation cost is reversed if the conditions ultimately are not met.

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Stock-based compensation for the three months ended February 28, 2026 and 2025 was approximately $0.5 million and $0.3 million, respectively, and for the nine months ended February 28, 2026 and 2025 was $0.8 million and $1.0 million, respectively. Stock-based compensation is recorded in general and administrative and research and development costs.

*Stock options*

Stock option activity is presented in the table below:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  |  |  | **Weighted**  |  |
|  |  |  | **average** |  |
|  |  | **Weighted** | **remaining** | **Aggregate** |
|  | **Number of** | **average** | **contractual** | **intrinsic** |
| *(in thousands, except per share data and years)* | **shares** | **exercise price** | **life in years** | **value** |
| Options outstanding at May 31, 2025 | 38324 | $0.46 | 7.65 | $4039 |
| Granted | 925 | $0.29 |  |  |
| Exercised | (100) | $0.21 |  | 6 |
| Forfeited, expired, and cancelled | (905) | $1.14 |  |  |
| Options outstanding at February 28, 2026 | 38244 | $0.44 | 6.98 | $1794 |
| Options outstanding and exercisable at February 28, 2026 | 31322 | $0.44 | 6.66 | $1320 |

---

During the nine months ended February 28, 2026 and 2025, stock options for approximately 0.9 million shares and 11.7 million shares, respectively, were granted. Of the options granted in the current year, approximately 0.6 million vest over four years, and approximately 0.3 million vest over one year. Of the options granted in the prior year, approximately 5.7 million vest over four years, and approximately 6.0 million vest over one year. The Company records compensation expense based on the Black-Scholes fair value per share of the awards on the grant date. The weighted average fair value per share was $0.26 and $0.12 for the stock options granted in the nine months ended February 28, 2026 and 2025, respectively.

*PSUs*

The following table summarizes the Company's PSU activity:

---

| | | | |
|:---|:---|:---|:---|
|  |  |  | **Weighted average** |
|  | **Number of** | **Weighted average** | **remaining contractual** |
| *(shares in thousands)* | **RSUs and PSUs (1)** | **grant date fair value** | **life in years** |
| Unvested PSUs at May 31, 2025 | 3500 | 0.41 | 1.75 |
| PSUs granted |  |  |  |
| PSUs forfeited |  |  |  |
| PSUs vested |  |  |  |
| Unvested PSUs at February 28, 2026 | 3500 | $0.41 | 1.00 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) The number of PSUs disclosed in this table are at the target level of 100% .

The vesting of the PSUs is subject to the achievement of specified performance-based conditions, and the actual number of common shares that will ultimately be issued will be determined by multiplying this number of PSUs by a payout percentage ranging from 0% to 100%.

Based on the estimated level of achievement of the performance targets associated with the PSUs as of February 28, 2026, unrecognized compensation expense related to the unvested portion of the Company's PSUs was $1.4 million, which is expected to be recognized over a weighted-average period of 1.0 years.

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#### Note 7. (Loss) Income per Share
Basic (loss) income per share is computed by dividing the net (loss) income adjusted for preferred stock dividends by the weighted average number of common shares outstanding during the period. Diluted (loss) income per share includes the weighted average common shares outstanding and potentially dilutive common stock equivalents. Basic and diluted (loss) income per share for the three and nine months ended February 28, 2026 and 2025 were calculated as follows:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Nine months ended February 28,** | **Nine months ended February 28,** |
| *(in thousands, except per share amounts)* | **2026** | **2025** | **2026** | **2025** |
| Numerator: |  |  |  |  |
| &nbsp;&nbsp;Net (loss) income | $(4690) | $(4758) | $(32837) | $9701 |
| &nbsp;&nbsp;Less: Accrued preferred stock dividends | (364) | (365) | (1106) | (1106) |
| &nbsp;&nbsp;Basic net (loss) income applicable to common stockholders | (5054) | (5123) | (33943) | 8595 |
| &nbsp;&nbsp;Diluted net (loss) income applicable to common stockholders | $(5054) | $(5123) | $(33943) | $8595 |
| Denominator: |  |  |  |  |
| &nbsp;&nbsp;Basic weighted average common shares outstanding | 1275184 | 1228259 | 1262834 | 1194561 |
| &nbsp;&nbsp;Effect of dilutive securities: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Warrant exercises |  |  |  | 30352 |
| &nbsp;&nbsp;&nbsp;&nbsp;Preferred stock conversions |  |  |  | 625 |
| &nbsp;&nbsp;Diluted weighted average common shares outstanding | 1275184 | 1228259 | 1262834 | 1225538 |
| Basic (loss) income per share | $(0.00) | $(0.00) | $(0.03) | $0.01 |
| Diluted (loss) income per share | $(0.00) | $(0.00) | $(0.03) | $0.01 |

---

The table below shows the approximate number of shares of common stock issuable upon the exercise, vesting, or conversion of outstanding options, PSUs, warrants, convertible notes, and convertible preferred stock (including undeclared dividends) that were not included in the computation of diluted weighted average number of shares of common stock outstanding for the periods presented:

---

| | | |
|:---|:---|:---|
|  | **Three and nine months ended February 28,** | **Three and nine months ended February 28,** |
| *(in thousands)* | **2026** | **2025** |
| Stock options, PSUs, and warrants | 341,956 | 231,027 |
| Convertible notes | 12,000 | 12,000 |
| Convertible preferred stock  | 42,232 | 39,265 |

---

#### Note 8. Income Taxes
**To determine the Company's quarterly provision for income taxes, the Company used an estimated annual effective tax rate that is based on expected annual income and statutory tax rates in the various jurisdictions in which the Company operates. Certain significant unusual or infrequently occurring items that are separately reported are separately recognized in the quarter during which they occur and can be a source of variability in the effective tax rate from quarter to quarter.**

**The Company had no income tax expense for the three and nine months ended February 28, 2026 and 2025. The provision for income taxes for the three and nine months ended February 28, 2026 and 2025 is based on the Company's estimated annualized effective tax rate for the fiscal years ending May 31, 2026 and 2025, respectively. For the three and nine months ended February 28, 2026, the Company's recognized effective tax rate differs from the U.S. federal statutory rate due to the Company maintaining a full valuation allowance on its net deferred tax assets, as the Company does not consider it more likely than not that the benefits from the net deferred tax assets will be realized.**

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**Note 9. Fair Value Measurement**

The following table provides information by level for assets and liabilities that are measured at fair value on a recurring basis.

---

| | | | |
|:---|:---|:---|:---|
| *(in thousands)* | **February 28, 2026** | **May 31, 2025** | **level** |
| Assets: |  |  |  |
| &nbsp;&nbsp;Cash | $13591 | $534 | Level 1 |
| &nbsp;&nbsp;Money market funds | 2064 | 11369 | Level 1 |
| Liabilities: |  |  |  |
| &nbsp;&nbsp;Common stock | $(12245) | $— | Level 1 |

---

Our investments in money market funds, and common stock are classified within Level 1 of the fair value hierarchy because they are valued using quoted market prices.

**Note 10. Commitments and Contingencies**

*Other Liabilities*

The $43.6 million balance recorded in other liabilities is conditional, and will only be due and payable, upon the Company achieving a qualifying "Revenue" event, as defined below. The Company has agreed to pay 20% of its qualifying Revenue generated in each calendar year, if any, with such payments to be applied to reduce the balance until it is repaid in full. Interest will not accrue on the balance throughout the prospective repayment period. Revenue is defined as:

"…the gross revenue generated by Client and its Affiliates, less the following items (if not previously deducted from the amount invoiced): (a) reasonable and customary trade, quantity, and cash discounts actually granted and legally permitted wholesaler chargebacks actually paid or credited by Client and its Affiliates to wholesalers of products; (b) reasonable, customary, and legally permitted rebates and retroactive price reductions actually granted; (c) freight charges for the delivery of products; (d) the portion of the administrative fees paid during the relevant time period to group purchasing organizations, pharmaceutical benefit managers and/or government-mandated Medicare or Medicaid Prescription Drug Plans relating specifically to the product; and (e) sales, use or excise taxes imposed and actually paid in connection with the sale of products (but excluding any value added taxes or taxes based on income or gross receipts)."

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*Operating lease commitments*

*The Company leases its principal office location in Vancouver, Washington (the "Vancouver Lease"). The Vancouver Lease expires on April 30, 2026. Consistent with the guidance in ASC 842, Leases, the Company has recorded this lease in its consolidated balance sheet as an operating lease. For the purpose of determining the right of use asset and associated lease liability, we determined that the renewal of the Vancouver lease was not reasonably probable. The lease does not include any restrictions or covenants requiring special treatment under ASC 842, Leases. Operating lease costs for the three months ended February 28, 2026 and 2025 were approximately $31.0 thousand and $26.0 thousand, respectively, and for the nine months ended February 28, 2026 and 2025 were approximately $0.1 million. Operating lease right-of-use assets are included in other non-current assets and the current portion of operating lease liabilities are included in accrued liabilities and compensation on the consolidated balance sheets. The following table summarizes the operating lease balances:*

---

| | | |
|:---|:---|:---|
| *(in thousands)* | **February 28, 2026** | **May 31, 2025** |
| *Assets* |  |  |
| Right-of-use asset | $33 | $130 |
| *Liabilities* |  |  |
| Current operating lease liability | $34 | $141 |
| Non-current operating lease liability |  |  |
| Total operating lease liability | $34 | $141 |

---

The minimum (base rental) lease payments are expected to be as follows as of February 28, 2026 (in thousands):

---

| | |
|:---|:---|
| **Fiscal Year** | **Amount**  |
| 2026 - 3 months remaining | $31 |
| Thereafter |  |
| Total operating lease payments | 31 |
| Less: imputed interest | 3 |
| Present value of operating lease liabilities | $34 |

---

Supplemental information related to operating leases was as follows:

---

| | |
|:---|:---|
|  | **February 28, 2026** |
| Weighted average remaining lease term | 0.2<br> years |
| Weighted average discount rate | 10.0% |

---

*PRO 140 Acquisition and Licensing Arrangements*

Refer to Note 9, *Commitments and Contingencies*, in the 2025 Form 10-K for additional information.

*Legal proceedings*

On November 30, 2025, the Company recorded an accrual of approximately $16.5 million, which was revalued to approximately $12.7 million as of February 28, 2026, related to the Securities Class Action Lawsuits described below. The Company did not record any other accruals related to the outcomes of the legal matters described below. It is not possible to determine the outcome of these proceedings, including the defense and other litigation-related costs and expenses that may be incurred by the Company, as the outcomes of legal proceedings are inherently uncertain.

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Therefore, it is possible that the ultimate outcome of any proceeding, if in excess of a recognized accrual, if any, could be material to the Company's consolidated financial statements.

*Conclusion of Investigations by Securities and Exchange Commission and Department of Justice*

In September 2025, the Securities and Exchange Commission ("SEC") and Department of Justice ("DOJ") informed the Company that their respective investigations were effectively closed, and that nothing further was required of the Company.

*Securities Class Action Lawsuits*

On March 17, 2021, a stockholder filed a putative class-action lawsuit (the "March 17, 2021 lawsuit") in the U.S. District Court for the Western District of Washington against the Company and certain former officers. The complaint generally alleges the defendants made false and misleading statements regarding the viability of leronlimab as a potential treatment for COVID-19. On April 9, 2021, a second stockholder filed a similar putative class action lawsuit in the same court, which the plaintiff voluntarily dismissed without prejudice on July 23, 2021. On August 9, 2021, the court appointed lead plaintiffs for the March 17, 2021 lawsuit. On December 21, 2021, lead plaintiffs filed an amended complaint, which is brought on behalf of an alleged class of those who purchased the Company's common stock between March 27, 2020 and May 17, 2021. The amended complaint generally alleges that the defendants violated Sections 10(b) and/or 20(a) of the Securities Exchange Act of 1934, as amended (the "Exchange Act") and Rule 10b-5 promulgated thereunder by making purportedly false or misleading statements concerning, among other things, the safety and efficacy of leronlimab as a potential treatment for COVID-19, the Company's CD10 and CD12 clinical trials, and its human immunodeficiency virus ("HIV") Biologic License Application ("BLA"). The amended complaint also alleges that the individual defendants violated Section 20A of the Exchange Act by selling shares of the Company's common stock purportedly while in possession of material nonpublic information. The amended complaint seeks, among other relief, a ruling that the case may proceed as a class action and unspecified damages and attorneys' fees and costs. On February 25, 2022, the defendants filed a motion to dismiss the amended complaint. On June 24, 2022, lead plaintiffs filed a second amended complaint. The second amended complaint was brought on behalf of an alleged class of those who purchased the Company's common stock between March 27, 2020 and March 30, 2022, makes similar allegations, names the same defendants, and asserts the same claims as the prior complaint, adds a claim for alleged violation of Section 10(b) of the Exchange Act and Rule 10b-5(a) and (c) promulgated thereunder, and seeks the same relief as the prior complaint. All defendants filed motions to dismiss the second amended complaint in whole or in part. By order dated June 25, 2025, the court denied defendants' motions to dismiss.

On November 23, 2025, the Company reached an agreement in principle to settle the putative class-action lawsuit. The agreement in principle provides for a payment by the Company to the class of $500,000 in cash and 49 million shares of common stock of the Company in exchange for the dismissal and release of all claims against all defendants in the class action. The agreement is subject to final documentation, court approval, and other conditions.

There can be no assurances as to the ultimate outcome of the class action, including that the final settlement agreement will be executed, that the settlement agreement, if executed, will include the terms and conditions currently anticipated by the Company, that such agreement will be approved by the court, or that any revised settlement terms, if applicable, will be finalized by the parties and approved by the court. A final, non-appealable closure of the litigation could take several months. The agreement in principle does not constitute an admission by the Company of any fault or liability and the Company does not admit fault or liability. If the settlement cannot be finalized by the parties or is not approved by the court, the Company will defend the class action vigorously and believes there are meritorious defenses and legal standards that must be met for, among other things, success by the plaintiffs on the merits. If the parties are unable to finalize the settlement, the class action could have a material adverse effect on the Company's financial condition, results of operations, and cash flows.

*Shareholder Derivative Lawsuits*

On June 4, 2021, a stockholder filed a purported derivative lawsuit against certain of the Company's former officers and directors, and the Company as a nominal defendant, in the U.S. District Court for the Western District of

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Washington. Two additional shareholder derivative lawsuits were filed against the same defendants in the same court on June 25, 2021 and August 18, 2021, respectively. The court has consolidated these three lawsuits for all purposes ("Consolidated Derivative Suit"). On January 20, 2022, the plaintiffs filed a consolidated complaint. The consolidated complaint generally alleges that the director defendants breached their fiduciary duties by allowing the Company to make false and misleading statements regarding, among other things, the safety and efficacy of leronlimab as a potential treatment for COVID-19, the Company's CD10 and CD12 clinical trials and its HIV BLA, and by failing to maintain an adequate system of oversight and controls. The consolidated complaint also asserts claims against one or more individual defendants for waste of corporate assets, unjust enrichment, contribution for alleged violations of the federal securities laws, and for breach of fiduciary duty arising from alleged insider trading. The consolidated complaint seeks declaratory and equitable relief, an unspecified amount of damages, and attorneys' fees and costs.

On January 29, 2024, two purported stockholders filed a purported derivative lawsuit against certain of the Company's former officers, certain current and former directors, and the Company as a nominal defendant, in the Delaware Court of Chancery. The complaint generally makes allegations similar to those set forth in the Consolidated Derivative Suit and asserts that the individual defendants breached their fiduciary duties by allowing the Company to make false and misleading statements and by failing to maintain an adequate system of oversight and controls. The complaint also asserts claims against certain individual defendants for breach of fiduciary duty arising from alleged insider trading.

On June 20, 2025, two other purported stockholders filed a purported derivative lawsuit against certain of the Company's former officers, certain former and current directors, a third-party individual, and the Company as a nominal defendant, in the Delaware Court of Chancery. The complaint generally asserts that the individual defendants breached their fiduciary duties by allowing the Company to make false and misleading statements, by failing to maintain an adequate system of oversight and controls, and/or by purportedly wrongfully refusing plaintiffs' demands that the Company's board investigate and initiate claims against certain of the Company's former officers and directors based on allegations and claims similar to those set forth in the complaint. The complaint also asserts claims against certain individual defendants arising from alleged insider trading. The parties have filed a stipulation and proposed order to consolidate this lawsuit with the January 2024 lawsuit.

The Company and the individual defendants deny all allegations of wrongdoing in the complaints and intend to vigorously defend the litigation. In light of the fact that the suit(s) is/are in an early stage and the claims do not specify an amount of damages, the Company cannot predict the ultimate outcome of the matter(s) and cannot reasonably estimate the potential loss or range of loss the Company may incur.

*Investor Lawsuit Seeking Issuance of Additional Shares*

In January 2025, two former investors and current shareholders filed an action against the Company in relation to a dispute over how many shares were issued to them following their direct investment(s) with the Company. The former investors claim that the final pricing utilized to calculate the issuance of shares to them in 2022 was incorrect, and that they are entitled to more shares than were issued. The complaint presents legal claims sounding in breach of fiduciary duty, misrepresentation, fraud, negligence, theft, and breach of contract.

The Company's position is that the claims are without any factual support, or support under applicable law and/or the underlying investment documents. The Company views this action as an attempt to extract more shares without further/fair investment and plans to vigorously defend itself.

#### Note 11. Segment Information
The Company's measure of segment profit or loss is net earnings or loss. The measure of segment assets is reported on the consolidated balance sheets as total assets.

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The following table is representative of the significant expense categories regularly provided to the CODM when managing the Company's single reporting segment.

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| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Nine months ended February 28,** | **Nine months ended February 28,** |
| *(in thousands, except for per share data)* | **2026** | **2025** | **2026** | **2025** |
| Expenses<sup>(1)</sup>: |  |  |  |  |
| &nbsp;&nbsp;General and administrative expense<sup>(2)</sup> | $1561 | $1334 | $4890 | $4785 |
| &nbsp;&nbsp;Research and development<sup>(3)</sup> | 4298 | 2329 | 10652 | 4460 |
| &nbsp;&nbsp;Return of clinical expenses |  |  |  | (24985) |
| &nbsp;&nbsp;Legal settlement loss |  |  | 16587 |  |
| &nbsp;&nbsp;Stock-based compensation expense | 444 | 340 | 807 | 1013 |
| Total operating expenses | 6303 | 4003 | 32936 | (14727) |
| Operating (loss) gain | (6303) | (4003) | (32936) | 14727 |
| &nbsp;&nbsp;Interest income | 15 | 173 | 166 | 441 |
| &nbsp;&nbsp;Interest on convertible notes | (614) | (1143) | (1934) | (3469) |
| &nbsp;&nbsp;Amortization of discount on convertible notes |  | (110) |  | (348) |
| &nbsp;&nbsp;Standby equity purchase agreement commitment fee |  |  | (325) |  |
| &nbsp;&nbsp;Issuance costs for private placement of shares and warrants through placement agent (Note 5) | (1628) |  | (1628) |  |
| &nbsp;&nbsp;Legal settlement revaluation | 3842 |  | 3842 |  |
| &nbsp;&nbsp;Loss on induced conversion |  |  |  | (1180) |
| &nbsp;&nbsp;Finance charges | (2) | (2) | (22) | (25) |
| &nbsp;&nbsp;Gain on restructuring of payables |  | 327 |  | 407 |
| &nbsp;&nbsp;Loss on derivatives |  |  |  | (852) |
| Segment net (loss) income | (4690) | (4758) | (32837) | 9701 |
| Reconciliation of profit or loss: |  |  |  |  |
| &nbsp;&nbsp;Adjustments or reconciling items |  |  |  |  |
| Consolidated net (loss) income | $(4690) | $(4758) | $(32837) | $9701 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) The significant expense categories and amounts align with the segment-level information that is regularly provided to the CODM.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) General and administrative expense for the three months ended February 28, 2026, and 2025 is net of approximately $0.1 million and $0.1 million, respectively, of stock-based compensation expense, and for the nine months ended February 28, 2026 and 2025 is net of approximately $0.3 million and $0.6 million, respectively, of stock-based compensation expense.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) Research and development expense for the three months ended February 28, 2026 and 2025 is net of $0.4 million and $0.2 million, respectively, of stock-based compensation expense, and for the nine months ended February 28, 2026 and 2025 is net of approximately $0.5 million and $0.4 million, respectively, of stock-based compensation expense. During the nine months ended February 28, 2025, research and development expense included the return of $25.0 million of clinical expenses in the settlement of a dispute with Amarex. See Note 9, Commitments and Contingencies – Legal Proceedings – Settlement of Amarex Dispute in the 2025 Form 10-K for additional discussion.

#### Note 12. Subsequent Events
*Extension(s) to April 2, 2021 and April 23, 2021 Notes*

On March 24, 2026, the Company and the holders of the April 2, 2021 and April 23, 2021 Notes (each a "Noteholder" and together, the "Noteholders") agreed to extend the maturity date of each of the Notes by 36 months (the "Extension Period"). In consideration, the Company agreed to make a monthly payment covering both Notes in the total amount of $1,000,000 to the Noteholders in the form of shares of common stock, calculated based on (i) the previous trading day's closing price, or (ii) the average of the closing prices for the previous five trading days, whichever is lower. Monthly payments will be made through the extended maturity dates of April 5, 2029 and April 23, 2029, respectively. The annual interest rate for each Note was also reduced to 5% as part of the extension.

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*Note conversion*

In March 2026, in satisfaction of the required monthly payment, the Company and the Noteholder of the April 23, 2021 Note entered into an exchange agreement, pursuant to which a portion of the April 23, 2021 Note was partitioned into a new note with an aggregate principal amount of approximately $0.8 million. The new note was exchanged concurrently for approximately 2.7 million shares of common stock.

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**Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations**

Certain information included in this quarterly report on Form 10-Q contains, or incorporates by reference, forward-looking statements that involve risks, uncertainties, and assumptions that are difficult to predict. Words and expressions reflecting optimism, satisfaction, or disappointment with current prospects, as well as words such as "believes," "intends," "estimates," "expects," "projects," "plans," "anticipates," and variations thereof, or the use of future tense, identify forward-looking statements, but their absence does not mean that a statement is not forward-looking.

Our forward-looking statements are not guarantees of performance, and actual results could vary materially from those contained in or expressed by such statements. In evaluating all such statements, we urge you to specifically consider various risks identified elsewhere in this quarterly report including Item 1A of Part II, as well as those set forth in Item 1A. *Risk Factors* in the 2025 Form 10-K, any of which could cause actual results to differ materially from those indicated by our forward-looking statements.

Our forward-looking statements reflect our current views with respect to future events and are based on currently available financial, economic, scientific, and competitive data and information about current business plans.

Forward-looking statements may include, among others, statements about leronlimab, its ability to have positive health outcomes, the Company's ability to implement a successful operating strategy for the development of leronlimab and thereby create shareholder value, the ability to obtain regulatory approval of the Company's drug products for commercial sales, and the strength of the Company's leadership team. The Company's forward-looking statements are not guarantees of performance, and actual results could vary materially from those contained in or expressed by such statements due to risks and uncertainties, including: (i) the regulatory determinations of leronlimab's safety and effectiveness to treat the disease and conditions for which we are studying the product by the FDA and, potentially, drug regulatory agencies in other countries; (ii) the Company's ability to raise additional capital to fund its operations; (iii) the Company's ability to meet its debt and other payment obligations; (iv) the Company's ability to enter into or maintain partnership or licensing arrangements with third parties; (v) the Company's ability to recruit and retain key employees; (vi) the timely and sufficient development, through internal resources or third-party consultants, of analyses of the data generated from the Company's clinical trials required by the FDA or other regulatory agencies in connection with applications for approval of the Company's drug product; (vii) the Company's ability to achieve approval of a marketable product; (viii) the design, implementation, and conduct of clinical trials; (ix) the results of any such clinical trials, including the possibility of unfavorable clinical trial results; (x) the market for, and marketability of, any product that is approved; (xi) the existence or development of vaccines, drugs, or other treatments that are viewed by medical professionals or patients as superior to the Company's products; (xii) regulatory initiatives, compliance with governmental regulations, and the regulatory approval process; (xiii) legal proceedings, investigations, or inquiries affecting the Company or its products, including the finalization of an agreement in principle to settle the class action litigation filed against the Company in the state of Washington; (xiv) stockholder actions or proposals with regard to the Company, its management, or its Board of Directors; (xv) general economic and business conditions; (xvi) changes in domestic and foreign political and social conditions; and (xvii) various other matters, many of which are beyond the Company's control.

We intend that all forward-looking statements made in this quarterly report will be subject to the safe harbor protection of the federal securities laws pursuant to Section 27A of the Securities Act and Section 21E of the Exchange Act, to the extent applicable. Except as required by law, we do not undertake any responsibility to update these forward-looking statements to address events or circumstances that occur after the date of this quarterly report. Additionally, we do not undertake any responsibility to update you on the occurrence of any unanticipated events that may cause actual results to differ from those expressed or implied by these forward-looking statements.

The following discussion and analysis of our financial condition and results of operations should be read in conjunction with our 2025 Form 10-K, and the other sections of this Form 10-Q, including our consolidated financial statements and related notes set forth in Part I, Item 1. This discussion and analysis contains forward-looking statements, including information about possible or assumed results of our financial condition, operations, plans, objectives, and performance that involve risks, uncertainties, and assumptions. The actual results may differ materially from those anticipated and set forth in such forward-looking statements.

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*Overview*

The Company is a clinical stage biotechnology company focused on the clinical development and potential commercialization of its product candidate, leronlimab, which is being studied for its potential in solid-tumor oncology.

Our current business strategy is to continue to pursue the clinical development of leronlimab, which may include the following:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. Continue the Phase II trial of leronlimab in patients with relapsed/refractory micro-satellite stable colorectal cancer;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. Conduct additional studies exploring leronlimab and its therapeutic potential in other solid-tumor oncology indications, including but not limited to metastatic Triple-Negative Breast Cancer; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. Continue our work researching and developing a new or modified long-acting version of leronlimab.

We may need significant additional funding to execute the above business strategy in full, which may include conducting a variety of additional pre-clinical studies and clinical trials, in furtherance of our efforts to obtain FDA approval to commercialize leronlimab. In addition to traditional fundraising, the Company will pursue non-dilutive financing opportunities, such as license agreements and co-development or strategic partnerships, to help implement its strategy.

*Corporate Developments*

Refer to Note 5*, Equity - Private Placement of Common Stock and Warrants through Placement Agent* and Item 1, Note 12, *Subsequent Events*.

*Fluctuations in operating results* 

The Company's operating results may fluctuate significantly depending on the outcomes, number and timing of pre-clinical and clinical studies, patient enrollment and/or completion rates in the studies, and their related effect on research and development expenses, regulatory and compliance activities, activities related to seeking FDA approval of our drug product, general and administrative expenses, professional fees, and legal and regulatory proceedings and related consequences. We require a significant amount of capital to continue to operate; therefore, we regularly conduct financing offerings to raise capital, which may result in various forms of non-cash interest expense or other expenses. Additionally, we periodically seek to negotiate settlement of debt payment obligations in exchange for equity securities of the Company and enter into warrant exchanges or modifications that may result in non-cash charges. Our ability to continue to fund operations will depend on our ability to raise additional funds. See the *Liquidity and Capital Resources* and *Going Concern* sections in this Item 2 of Part I, Item 1A of Part II of this report, and Item 1A. *Risk Factors* in our 2025 Form 10-K.

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The results of operations were as follows for the periods presented:

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| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Change** | **Nine months ended February 28,** | **Nine months ended February 28,** | **Change** |
| *(in thousands, except for per share data)* | **2026** | **2025** | $**%** | **2026** | **2025** | $% |
| Operating expenses: |  |  |  |  |  |  |
| &nbsp;&nbsp;General and administrative | $1654 | $1516 | 9% | $5166 | $5423 | (5)% |
| &nbsp;&nbsp;Research and development | 4649 | 2487 | 87 | 11183 | (20150) | 155 |
| &nbsp;&nbsp;Legal settlement loss |  |  |  | 16587 |  | 100 |
| Total operating expenses | 6303 | 4003 | 57 | 32936 | (14727) | 324 |
| Operating (loss) gain  | (6303) | (4003) | (57) | (32936) | 14727 | (324) |
| Interest and other income (expense): |  |  |  |  |  |  |
| &nbsp;&nbsp;Interest income | 15 | 173 | (91) | 166 | 441 | (62) |
| &nbsp;&nbsp;Interest on convertible notes | (614) | (1143) | 46 | (1934) | (3469) | 44 |
| &nbsp;&nbsp;Amortization of discount on convertible notes |  | (110) | 100 |  | (348) | 100 |
| &nbsp;&nbsp;Standby equity purchase agreement commitment fee |  |  |  | (325) |  | (100) |
| &nbsp;&nbsp;Issuance costs for private placement of shares and warrants through placement agent | (1628) |  | (100) | (1628) |  | (100) |
| &nbsp;&nbsp;Legal settlement revaluation | 3842 |  | 100 | 3842 |  | 100 |
| &nbsp;&nbsp;Loss on induced conversion |  |  |  |  | (1180) | 100 |
| &nbsp;&nbsp;Finance charges | (2) | (2) |  | (22) | (25) | 12 |
| &nbsp;&nbsp;Gain on restructuring of payables |  | 327 | (100) |  | 407 | (100) |
| &nbsp;&nbsp;Loss on derivatives |  |  |  |  | (852) | 100 |
| Total interest and other expenses | 1613 | (755) | 314 | 99 | (5026) | 102 |
| (Loss) gain before income taxes | (4690) | (4758) | 1 | (32837) | 9701 | (438) |
| Income tax benefit |  |  |  |  |  |  |
| Net (loss) income | $(4690) | $(4758) | 1% | $(32837) | $9701 | (438)% |
| (Loss) income per share: |  |  |  |  |  |  |
| Basic | $(0.00) | $(0.00) | (100)% | $(0.03) | $0.01 | (400)% |
| Diluted | $(0.00) | $(0.00) | (100)% | $(0.03) | $0.01 | (400)% |
| Weighted average common shares used in calculation of (loss) income per share: |  |  |  |  |  |  |
| Basic | 1275184 | 1228259 | 4 | 1262834 | 1194561 | 6% |
| Diluted | 1275184 | 1228259 | 4 | 1262834 | 1225538 | 3% |

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*General and administrative ("G&A") expenses*

G&A expenses consisted of the following:

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Change** |  | **Nine months ended February 28,** | **Nine months ended February 28,** | **Change** |
| *(in thousands)* | **2026** | **2025** | $**%** |  | **2026** | **2025** | $**%** |
| Salaries, benefits, and other compensation | $584 | $379 | 54 | % | $1571 | 1139 | 38% |
| Stock-based compensation | 93 | 182 | (49) |  | 276 | 638 | (57) |
| Legal fees | 326 | 235 | 39 |  | 993 | 1374 | (28) |
| Insurance | 284 | 301 | (6) |  | 824 | 944 | (13) |
| Other | 367 | 419 | (12) |  | 1502 | 1328 | 13 |
| &nbsp;&nbsp;Total general and administrative | $1654 | $1516 | 9 | % | $5166 | $5423 | (5)% |

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The increase in G&A expenses for the three-month period ended February 28, 2026, compared to the same period in the prior year, was primarily due to salaries, benefits, and other compensation, primarily attributable to headcount increases.

The decrease in G&A expenses for the nine-month period ended February 28, 2026, compared to the same period in the prior year, was primarily due to legal fees and stock-based compensation, offset by an increase in salaries, benefits, and other compensation. The decrease in legal fees is primarily attributable to decreased legal activity compared to the prior year. The decrease in stock-based compensation is primarily due to difference in timing of annual option grants. The increase in salaries, benefits, and other compensation is primarily attributable to headcount increases.

*Research and development ("R&D") expenses*

R&D expenses consisted of the following:

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| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Change** | **Nine months ended February 28,** | **Nine months ended February 28,** | **Change** |
| *(in thousands)* | **2026** | **2025** | $**%** | **2026** | **2025** | $**%** |
| Clinical | $4323 | $1828 | 136% | $9338 | $3388 | 176% |
| Non-clinical | 320 | 371 | (14) | 741 | 700 | 6 |
| CMC | 404 | 597 | (32) | 1227 | 957 | 28 |
| License and patent fees | (398) | (309) | 29 | (123) | (210) | (41) |
| Return of clinical expenses |  |  |  |  | (24985) | (100) |
| &nbsp;&nbsp;Total research and development | $4649 | $2487 | 87% | $11183 | $(20150) | (155)% |

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The increases in R&D expenses in the three- and nine-month periods ended February 28, 2026, compared to the same periods in the prior year, were due to higher clinical expenses related to the Phase II trial of leronlimab in patients with relapsed/refractory micro-satellite stable colorectal cancer in the fiscal 2026 periods. Additionally with regard to the nine-month period ended February 28, 2026, the primary factor contributing to the increase in R&D expenses was a return of clinical expenses related to the settlement of the Company's litigation with Amarex in the nine-month period ended February 28, 2025.

The future trend of our R&D expenses is dependent on the costs of any future clinical trials and our decisions regarding which indications on which to focus our future efforts toward the development and study of leronlimab, which may include pre-clinical and clinical studies for oncology and inflammation, as well as efforts to develop a long-acting new or modified therapeutic, and the timing and outcomes of such efforts.

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*Interest and other income (expense)*

Interest and other income (expense) consisted of the following:

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| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | **Three months ended February 28,** | **Three months ended February 28,** | **Change** | **Nine months ended February 28,** | **Nine months ended February 28,** | **Change** |
| *(in thousands)* | **2026** | **2025** | $**%** | **2026** | **2025** | $**%** |
| Interest income | $15 | $173 | (91)% | $166 | 441 | (62)<br>**%** |
| Interest on convertible notes | (614) | (1143) | 46 | (1934) | $(3469) | (44) |
| Amortization of discount on convertible notes |  | (110) | 100 |  | (348) | (100) |
| Standby equity purchase agreement commitment fee |  |  |  | (325) |  | 100 |
| Issuance costs for private placement of shares and warrants through placement agent (Note 5) | (1628) |  | (100) | (1628) |  | (100) |
| Legal settlement revaluation | 3842 |  | 100 | 3842 |  | 100 |
| Loss on induced conversion |  |  |  |  | (1180) | (100) |
| Finance charges | (2) | (2) |  | (22) | (25) | (12) |
| Gain on restructuring of payables |  | 327 | (100) |  | 407 | (100) |
| Loss on derivatives |  |  |  |  | (852) | (100) |
| &nbsp;&nbsp;Total interest and other expenses | $1613 | $(755) | (314)% | $99 | $(5026) | (102)% |

---

The decrease in interest and other expenses for the three-month period ended February 28, 2026, compared with the same period in the prior year, was primarily due to the legal settlement revaluation, which is related to the change in value of the Securities Class Action Lawsuits settlement. The decrease was partially offset by an increase in issuance costs related to the private placement of common stock and warrants through a placement agent.

The decrease in interest and other expenses for the nine-month period ended February 28, 2026, compared with the same period in the prior year, was primarily due to the legal settlement revaluation, interest on convertible notes payable, loss on induced conversion, and loss on derivatives. The legal settlement revaluation is related to the change in value of the Securities Class Action Lawsuits settlement. The decrease in interest on convertible notes payable is due to a lower interest rate compared to the prior period. The decrease in loss on induced conversion is due to the note payments in the current fiscal year being exchanged with an equal value of shares of common stock. The decrease in loss on derivatives is due to no derivative activity in the fiscal 2026 period. The decrease in interest and other expenses for the nine-month period ended February 28, 2026 was partially offset by issuance costs related to the private placement of common stock and warrants through a placement agent.

***Liquidity and Capital Resources***

As of February 28, 2026, we had a total of approximately $15.7 million in cash and cash equivalents and approximately $50.4 million in short-term liabilities. We expect to continue to incur operating losses and require a significant amount of capital in the future as we continue to seek approval to commercialize leronlimab. There can be no assurance that future funding will be available to us when needed on terms that are acceptable to us, or at all. We sell securities and incur debt when the terms of such arrangements are deemed acceptable to both parties under then current circumstances and as necessary to fund our current and projected cash needs. As of February 28, 2026, we had approximately 312.8 million shares of common stock available for issuance in new financing transactions.

Since inception, the Company has financed its activities principally from the public and private sale of equity securities as well as with proceeds from issuances of convertible notes. The Company intends to finance its future operating activities and its working capital needs largely from the sale of equity and debt securities. The sale of equity and convertible debt securities to raise additional capital is likely to result in dilution to stockholders and those securities may have rights senior to those of common shares. If the Company raises funds through the issuance of additional preferred stock, convertible debt securities or other debt or equity financing, the related transaction documents may contain covenants restricting its operations.

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During the 2021 fiscal year, the Company entered into long-term convertible notes that are secured by all of our assets (excluding our intellectual property), and include certain restrictive provisions, including limitations on incurring additional indebtedness and future dilutive issuances of securities, any of which could impair our ability to raise additional capital on acceptable terms.

On November 3, 2025, the Company entered into a purchase agreement with Yorkville pursuant to which the Company has the right to sell to the Investor up to $30.0 million of its shares of common stock, subject to certain limitations and conditions set forth in the Purchase Agreement, from time to time during the term of the Purchase Agreement.

Future third-party funding arrangements may also require the Company to relinquish valuable rights. Additional capital, if available, may not be available on reasonable or non-dilutive terms.

*Cash and cash equivalents*

The Company's cash and cash equivalents position of approximately $15.7 million as of February 28, 2026, increased by approximately $3.8 million when compared to the balance of $11.9 million as of May 31, 2025. This increase was primarily the result of approximately $16.1 million cash provided by financing activities offset by operational expenses. Refer to Item 1, Note 2, *Summary of Significant Accounting Policies – Going Concern*, and the *Going Concern* discussion below for information regarding concerns about the Company's ability to continue to fund its operations and satisfy its payment obligations and commitments. A summary of cash flows and changes between the periods presented is as follows:

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| | | | |
|:---|:---|:---|:---|
|  | **Nine months ended February 28,** | **Nine months ended February 28,** | **Change** |
| *(in thousands)* | **2026** | **2025** | **$**  |
| Net cash (used in) provided by: |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash (used in) provided by operating activities  | $(12319) | $(3102) | $(9217) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash (used in) provided by financing activities  | $16071 | $9688 | $6383 |

---

*Cash used in operating activities*

Net cash used in operating activities totaled approximately $12.3 million during the nine months ended February 28, 2026, representing an increase of approximately $9.2 million compared to the nine months ended February 28, 2025. The increase in the net amount of cash used in operating activities was due primarily to a one-time legal settlement of approximately $10.0 million in the prior period.

*Cash provided by financing activities*

Net cash used in financing activities totaled approximately $16.1 million during the nine months ended February 28, 2026, an increase of approximately $6.4 million compared to the nine months ended February 28, 2025. The increase in net cash provided was primarily the result of the private sale of common stock and warrants.

[**Table of Contents**](#TOC)

*Convertible debt* 

*April 2, 2021 Convertible Note*

On April 2, 2021, we issued a convertible note with a principal amount of $28.5 million, resulting in net cash proceeds of $25.0 million after $3.4 million of debt discount and $0.1 million of offering costs. At February 28, 2026, the Note terms provided for accruing interest daily at a rate of 6% per annum, a stated conversion price of $10.00 per share, and maturity in April 2026. Subsequent to February 28, 2026, the Company and the Noteholders entered into an amendment to the Note, extending the maturity date by 36 months, changing the required monthly payment, and lowering the interest rate to 5%. For more information, see Note 12, *Subsequent Events* in Part I, Item 1 of this Form 10-Q. As of February 28, 2026, the outstanding balance of the April 2, 2021 Note, including accrued interest, was approximately $8.6 million.

*April 23, 2021 Convertible Note*

On April 23, 2021, we issued a convertible note with a principal amount of $28.5 million, resulting in net cash proceeds of $25.0 million after $3.4 million of debt discount and $0.1 million of offering costs. At February 28, 2026, the Note terms provided for accruing interest daily at a rate of 6% per annum, a stated conversion price of $10.00 per share, and maturity in April 2026. Subsequent to February 28, 2026, the Company and the Noteholders entered into an amendment to the Note, extending the maturity date by 36 months, changing the required monthly payment, and lowering the interest rate to 5%. For more information, see Note 12, *Subsequent Events* in Part I, Item 1 of this Form 10-Q. As of February 28, 2026, the outstanding balance of the April 23, 2021 Note, including accrued interest, was approximately $31.9 million. In March 2026, in satisfaction of the required monthly payment, the Company and the Noteholder of the April 23, 2021 Note entered into an exchange agreement, pursuant to which a portion of the April 23, 2021 Note was partitioned into a new note with an aggregate principal amount of approximately $0.8 million. The new note was exchanged concurrently for approximately 2.7 million shares. Refer to Item 1, Note 12. *Subsequent Events*.

*Common stock*

We have 2,250.0 million authorized shares of common stock. The table below summarizes intended uses of common stock.

---

| | |
|:---|:---|
| *(in millions)* | **As of**<br>**February 28, 2026** |
| Issuable upon: |  |
| &nbsp;&nbsp;Warrant exercises | 300.2 |
| &nbsp;&nbsp;Convertible preferred stock and undeclared dividends conversion  | 42.2 |
| &nbsp;&nbsp;Outstanding stock option exercises or vesting of outstanding PSUs | 41.7 |
| Reserved for issuance pursuant to future stock-based awards under equity incentive plan | 18.6 |
| Reserved for issuance under Standby Equity Purchase Agreement | 115.5 |
| Reserved for issuance pursuant to legal settlement, subject to court approval | 49.0 |
| Reserved and issuable upon conversion of outstanding convertible notes | 12.0 |
| Total shares reserved for future uses | 579.2 |
| Common stock outstanding | 1358.0 |

---

As of February 28, 2026, we had approximately 312.8 million unreserved authorized shares of common stock available for issuance. Our ability to continue to fund our operations depends on our ability to raise capital. The funding necessary for our operations may not be available on acceptable terms, or at all. If we deplete our cash reserves, we may have to discontinue our operations and liquidate our assets. In extreme cases, we could be forced to file for bankruptcy protection.

[**Table of Contents**](#TOC)

***Off-Balance Sheet Arrangements***

As of February 28, 2026, we did not have any off-balance sheet arrangements that have, or are reasonably likely to have, a material effect on our current or future financial condition, results of operations, liquidity, capital expenditures or capital resources.

***Contractual Obligations***

Refer to Note 3, *Accrued Liabilities and Compensation*, Note 4, *Convertible Instruments and Accrued Interest*, and Note 10*, Commitments and Contingencies* included in Part I, Item 1 of this Form 10-Q, and Notes 4 and 9 in Part II, Item 8 in the 2025 Form 10-K.

***Legal Proceedings***

The Company is a party to various legal proceedings described in Part I, Item 1, Note 10, *Commitments and Contingencies – Legal Proceedings* of this Form 10-Q. The Company recognizes accruals for such proceedings to the extent a loss is determined to be both probable and reasonably estimable. The best estimate of a loss within a possible range is accrued; however, if no estimate in the range is more probable than another, then the minimum amount in the range is accrued. If it is determined that a material loss is not probable but reasonably possible and the loss or range of loss can be estimated, the possible loss is disclosed.

It generally is not possible to predict the outcome of these proceedings, including the defense and other litigation-related costs and expenses that may be incurred by the Company, as the outcomes of legal proceedings are inherently uncertain, and the outcomes could differ significantly from recognized accruals. Therefore, it is possible that the ultimate outcome of any proceeding, if in excess of a recognized accrual, if any, could be material to the Company's consolidated financial statements. As of February 28, 2026, the Company had not recorded any accruals related to the outcomes of the legal matters discussed in this Form 10-Q, other than approximately $12.7 million in connection with an agreement in principle to settle the Securities Class Action, as discussed above under "*Corporate Developments.*".

***Going Concern***

The accompanying consolidated financial statements have been prepared on a going concern basis, which contemplates the realization of assets and the satisfaction of liabilities in the normal course of business. As presented in the accompanying consolidated financial statements, the Company had losses for all periods presented, except for the nine months ended February 28, 2025. Net income of $9.7 million in the nine months ended February 28, 2025, resulted from the recovery of approximately $25.0 million in clinical expenses due to the settlement of the Company's litigation with Amarex, which is a non-recurring event. The Company had an accumulated deficit of approximately $920.6 million as of February 28, 2026. These factors, among several others, raise substantial doubt about our ability to continue as a going concern. The consolidated financial statements do not include any adjustments relating to the recoverability and classification of assets and liabilities that might be necessary should the Company be unable to continue as a going concern.

The Company's continuance as a going concern is dependent upon its ability to obtain additional operating capital, complete the development of its product candidate, leronlimab, obtain approval to commercialize leronlimab from regulatory agencies, continue to outsource manufacturing of leronlimab, and ultimately achieve revenues and attain profitability. The Company plans to continue to engage in research and development activities related to leronlimab and a new or modified longer-acting therapeutic and expects to incur significant research and development expenses in the future, primarily related to its regulatory compliance, including performing additional clinical trials and seeking regulatory approval of its product candidate for commercialization. These research and development activities are subject to significant risks and uncertainties. The Company intends to finance its future development activities and its working capital needs primarily from the sale of equity and debt securities, combined with additional funding from other sources. However, there can be no assurance that the Company will be successful in these endeavors. See also *Liquidity and Capital Resources* above.

[**Table of Contents**](#TOC)

***New Accounting Pronouncements***

Refer to Part I, Item 1, Note 2, *Summary of Significant Accounting Policies – Recent Accounting Pronouncements* in this Form 10-Q for the discussion.

***Critical Accounting Estimates***

This discussion and analysis of the Company's financial condition and results of operations is based on our consolidated financial statements, which have been prepared in accordance with GAAP. The preparation of our financial statements and related disclosures requires management to make estimates and judgments that affect the reported amounts of assets, liabilities, the disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. The Company's critical accounting estimates are described under the heading *Management's Discussion and Analysis of Financial Condition and Results of Operations — Critical Accounting Estimates* in our 2025 Form 10-K.

#### Item 3. Quantitative and Qualitative Disclosures about Market Risk
There have been no material changes from the information previously reported in Part II, Item 7A of the 2025 Form 10-K.

#### Item 4. Controls and Procedures
We maintain disclosure controls and procedures that are designed to ensure that information required to be disclosed in the reports that we file or submit under the Exchange Act, is (1) recorded, processed, summarized and reported within the time periods specified in the SEC's rules and forms, and (2) accumulated and communicated to our management, including our Chief Executive Officer and Chief Financial Officer, as appropriate to allow timely decisions regarding required disclosure.

Our management, with the participation of our Chief Executive Officer and Chief Financial Officer, evaluated the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act) as of February 28, 2026. Our management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving their objectives, and management necessarily applies its judgment in evaluating the cost-benefit relationship of possible controls and procedures. Our Chief Executive Officer and Chief Financial Officer concluded, based upon the evaluation described above, that as of February 28, 2026, our disclosure controls and procedures were effective at the reasonable assurance level.

During the quarter ended February 28, 2026, there have been no changes in our internal control over financial reporting, as such term is defined in Rules 13a-15(f) and 15(d)-15(f) promulgated under the Exchange Act, that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

[**Table of Contents**](#TOC)

**PART II – Other Information**

#### Item 1. Legal Proceedings
**For a description of pending material legal proceedings, please see Note 10, *Commitments and Contingencies–Legal Proceedings*, of the Notes to Consolidated Financial Statements included in Part I, Item 1 of this Form 10-Q.**

#### Item 1A. Risk Factors
We are subject to various risks, including risk factors identified in our 2025 Form 10-K. You should carefully consider those risk factors in addition to other information in this Form 10-Q.

#### Item 2. Unregistered Sales of Equity Securities and Use of Proceeds
*Issuances of Shares in Convertible Note Exchange Transactions*

In March 2026, the Company and the holder of its April 23, 2021 Note, in partial satisfaction of the holder's redemption rights, entered into an exchange agreement pursuant to which a portion of the original note was partitioned into new notes with a principal amount of approximately $0.8 million. The new note was exchanged concurrently with issuance of a total of approximately 2.7 million shares of common stock. The Company relied on the exemption provided by Section 3(a)(9) of the Securities Act in connection with the exchange transaction.

[**Table of Contents**](#TOC)

**Item 6. Exhibits**

(a)Exhibits:

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | | | **Incorporated by Reference** | **Incorporated by Reference** | **Incorporated by Reference** |
| <br>**ExhibitNo** | <br>**Description** | <br>**FiledHerewith** | **Form** | **Exhibit No.** | **Filing Date** |
| 10.1 | [Amendment to Security Agreement between CytoDyn Inc. and Streeterville Capital, LLC, dated April 2, 2021](cydy-20260228xex10d1.htm) | X |  |  |  |
| 10.2 | [Amendment to Security Agreement between CytoDyn Inc. and Uptown Capital, LLC, dated April 23, 2021](cydy-20260228xex10d2.htm) | X |  |  |  |
| <br>31.1 | <br>[Rule 13a-14(a) Certification by Principal Executive Officer of the Registrant.](cydy-20260228xex31d1.htm)<br>| X |  |  |  |
| 31.2 | [Rule 13a-14(a) Certification by Principal Financial Officer of the Registrant.](cydy-20260228xex31d2.htm) | X |  |  |  |
| 32 | [Certification of Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350.\*](cydy-20260228xex32.htm) | X |  |  |  |
| 101.INS | Inline XBRL Instance Document. | X |  |  |  |
| 101.SCH | Inline XBRL Taxonomy Extension Schema Document. | X |  |  |  |
| 101.CAL | Inline XBRL Taxonomy Extension Calculation Linkbase Document. | X |  |  |  |
| 101.DEF | Inline XBRL Taxonomy Extension Definition Linkbase Document. | X |  |  |  |
| 101.LAB | Inline XBRL Taxonomy Extension Label Linkbase Document. | X |  |  |  |
| 101.PRE | Inline XBRL Taxonomy Extension Presentation Linkbase Document. | X |  |  |  |
| 104 | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). | X |  |  |  |

---

\*Furnished, not filed.

[**Table of Contents**](#TOC)

#### SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  | CYTODYN INC. | CYTODYN INC. |
|  | (Registrant) | (Registrant) |
| Dated: April 8, 2026 |  | /s/ Jacob Lalezari |
|  |  | Jacob Lalezari |
|  |  | Chief Executive Officer |
|  |  | (Principal Executive Officer)<br>|

---

---

| | |
|:---|:---|
| Dated: April 8, 2026 | /s/ Robert E. Hoffman  |
|  | Robert E. Hoffman |
|  | Chief Financial Officer |
|  | (Principal Financial and Accounting Officer)<br>|

---

## Exhibit 10.1

#### Exhibit 10.1

#### AMENDMENT #2 TO SECURED CONVERTIBLE PROMISSORY NOTE
This Amendment #2 to Secured Convertible Promissory Note (this "**Amendment**") is entered into as agreed upon on March 24, 2026, by and between STREETERVILLE CAPITAL, LLC, a Utah limited liability company ("**Lender**"), and CYTODYN, INC., a Delaware corporation ("**Borrower**"). Capitalized terms used in this Amendment without definition shall have the meanings given to them in the Note (as defined below).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A.Borrower previously issued to Lender a Secured Convertible Promissory Note dated April 2, 2021 in the principal amount of $28,500,000.00 (the "**Note**").

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;B.Effective as of April 5, 2025, Borrower and Lender entered into that certain Amendment to Secured Convertible Promissory Note (the "**Prior Amendment**"), pursuant to which, among other modifications, Borrower and Lender agreed to extend the Maturity Date of the Note.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;C.Borrower has requested that Lender again extend the Maturity Date of the Note (the "**Extension**") and temporarily reduce the interest rate.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;D.Lender has agreed, subject to the terms, amendments, conditions, and understandings expressed in this Amendment, to grant the Extension and reduce the interest rate.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which is acknowledged, the parties agree as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.<u>Recitals</u>. Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Amendment are true and accurate and are hereby incorporated into and made a part of this Amendment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.<u>Extension</u>. The Maturity Date for the Note is hereby extended until April 5, 2029 (the "**Extension Period**").

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.<u>Monthly Payment Term(s) on Note During Extension Period</u>. Beginning in April 2026, on the 20th day of each calendar month (or the next Trading Day if a weekend or holiday) during the Extension Period, Borrower will calculate a number of shares of common stock equal to $1,000,000.00 (the "**Monthly Payment Amount**") divided by the lower of: (a) the immediately preceding Closing Trade Price, and (b) the average of the five (5) previous Closing Trade Prices (the "**Monthly Payment Shares**"). Within two (2) Trading Days of the applicable calculation date, Borrower will request that its transfer agent, Computershare, issue the calculated shares to Lender, and deliver such shares within four (4) Trading Days of the applicable calculation date (provided that Lender has delivered all applicable documentation to Computershare). In the event Borrower's common stock is either not trading on its principal market or is not available for immediate resell by Lender on the applicable calculation date and delivery date, then the Monthly Payment Amount must be paid to Lender in cash within fifteen (15) days of the date the share issuance was due to Lender.

------

For the avoidance of doubt, Chicago Venture Partners ("**CVP**") currently holds two notes with Borrower – one in the name of Uptown Capital, LLC and another in the name of Streeterville Capital, LLC – and the Monthly Payment Amount will accrue and be applicable to one of the two notes on a monthly basis. CVP may, at its discretion, choose which of the two notes it would like to apply the Monthly Payment Amount to on a month-by-month basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.<u>Interest Rate</u>. During the Extension Period, the interest rate on the Note will decrease to five percent (5%).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5.<u>Failure</u><u> </u><u>to Make a Monthly</u><u> </u><u>Payment</u>. In the event Borrower fails to timely make a Monthly Payment (whether in cash or by delivery of Monthly Delivery Shares, as applicable), recourse to Lender will be as follows (i) in the first event of any missed payment/issuance, Borrower will have five (5) business days to cure the default; (ii) for any default thereafter, or in the event the first default is not timely cured: (a) the Extension Period will immediately terminate,

(b) the Note will become immediately due and payable in full, (c) Default Interest will begin accruing on the Note, and (d) the difference between the interest accrued during the Extension Period at the reduced interest rate and the amount that would have accrued at the original ten percent (10%) interest rate during the Extension Period will automatically be added to the Outstanding Balance.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;6.<u>Representations and Warranties</u>. Each party, for itself, and for its affiliates, successors and assigns, hereby acknowledges, represents, warrants and agrees as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)Each of the parties has full power and authority to enter into this Amendment and to incur and perform all obligations and covenants contained herein, all of which have been duly authorized by all proper and necessary action. No consent, approval, filing or registration with or notice to any governmental authority is required as a condition to the validity of this Amendment or the performance of any of the obligations of the parties hereunder.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)Borrower represents that there is no fact known to Borrower or which should be known to Borrower which Borrower has not disclosed to Lender on or prior to the date of this Amendment which would or could materially and adversely affect the understanding of Lender expressed in this Amendment or any representation, warranty, or recital contained in this Amendment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)Except as expressly set forth in this Amendment, Borrower acknowledges and agrees that neither the execution and delivery of this Amendment nor any of the terms, provisions, covenants, or agreements contained in this Amendment shall in any manner release, impair, lessen, modify, waive, or otherwise affect the liability and obligations of Borrower under the terms of the Transaction Documents.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d)As of the effective date of this Amendment, Borrower has no known defenses against Lender, directly or indirectly, arising out of, based upon, or in any manner connected with, the transactions contemplated, which occurred, existed, was taken, permitted, or begun prior to the effective date of this Amendment and occurred, existed, was taken, permitted or begun in accordance with, pursuant to, or by virtue of any of the terms or conditions of the

------

Transaction Documents. To the extent any such defenses existed as of the effective date of this Amendment, such defenses are hereby waived, discharged, and released. Borrower hereby acknowledges and agrees that the execution of this Amendment by Lender shall not constitute an acknowledgment of or admission by Lender of the existence of any claims or of liability for any matter or precedent upon which any claim or liability may be asserted.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e)Each of the parties represents and warrants that as of the date hereof no Events of Default or other material breaches exist under the Transaction Documents or have occurred prior to the date hereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;7.<u>Certain Acknowledgments</u>. Each of the parties acknowledges and agrees that no property or cash consideration of any kind whatsoever has been or shall be given by Lender to Borrower in connection with the Extension or any other amendment to the Note granted herein.

8<u>Other</u><u> </u><u>Terms Unchanged</u>. The Note, as amended by this Amendment and the Prior Amendment, remains and continues in full force and effect, constitutes legal, valid, and binding obligations of each of the parties, and is in all respects agreed to, ratified, and confirmed. Any reference to the Note after the date of this Amendment is deemed to be a reference to the Note as amended by this Amendment. If there is a conflict between the terms of this Amendment, the Prior Amendment, and the Note, the terms of this Amendment shall control. No forbearance or waiver may be implied by this Amendment. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver of, or as an amendment to, any right, power, or remedy of Lender under the Note, as in effect prior to the date hereof. For the avoidance of doubt, this Amendment shall be subject to the governing law, venue, and Arbitration Provisions, as set forth in the Note.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;9.<u>No</u><u> </u><u>Reliance</u>. Borrower acknowledges and agrees that neither Lender nor any of its officers, directors, members, managers, equity holders, representatives, or agents has made any representations or warranties to Borrower or any of its agents, representatives, officers, directors, or employees except as expressly set forth in this Amendment and the Transaction Documents and, in making its decision to enter into the transactions contemplated by this Amendment, Borrower is not relying on any representation, warranty, covenant, or promise of Lender or its officers, directors, members, managers, equity holders, agents or representatives other than as set forth in this Amendment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;10.<u>Counterparts</u>. This Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall constitute one instrument. The parties hereto confirm that any electronic copy of another party's executed counterpart of this Amendment (or such party's signature page thereof) will be deemed to be an executed original thereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;11.<u>Further Assurances</u>. Each party shall do and perform or cause to be done and performed, all such further acts and things, and shall execute and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to carry out the intent and accomplish the purposes of this Amendment and the consummation of the transactions contemplated hereby.

------

*[Remainder of page intentionally left blank]*

------

IN WITNESS WHEREOF, the undersigned have executed this Amendment as of the date set forth above.

#### LENDER:
Streeterville Capital, LLC

By: <u>/s/ John M. Fife</u> John M. Fife, President

#### BORROWER:
CytoDyn, Inc.

By: <u>/s/ Robert E. Hoffman</u> <sup>Name:</sup><u> </u><u>Robert Hoffman</u> 

Title: <u> </u><u>CFO</u> 

*[Signature Page to Amendment #2 to Secured Convertible Promissory Note]*

------

## Exhibit 10.2

#### Exhibit 10.2

#### AMENDMENT #2 TO SECURED CONVERTIBLE PROMISSORY NOTE
This Amendment #2 to Secured Convertible Promissory Note (this "**Amendment**") is entered into as agreed upon on March 24, 2026, by and between UPTOWN CAPITAL, LLC, a Utah limited liability company ("**Lender**"), and CYTODYN, INC., a Delaware corporation ("**Borrower**"). Capitalized terms used in this Amendment without definition shall have the meanings given to them in the Note (as defined below).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A.Borrower previously issued to Lender a Secured Convertible Promissory Note dated April 23, 2021 in the principal amount of $28,500,000.00 (the "**Note**").

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;B.B. Effective as of April 23, 2025, Borrower and Lender entered into that certain Amendment to Secured Convertible Promissory Note (the "**Prior Amendment**"), pursuant to which, among other modifications, Borrower and Lender agreed to extend the Maturity Date of the Note.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;C.Borrower has requested that Lender again extend the Maturity Date of the Note (the "**Extension**") and temporarily reduce the interest rate.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;D.Lender has agreed, subject to the terms, amendments, conditions, and understandings expressed in this Amendment, to grant the Extension and reduce the interest rate.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which is acknowledged, the parties agree as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.<u>Recitals</u>. Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Amendment are true and accurate and are hereby incorporated into and made a part of this Amendment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.<u>Extension</u>. The Maturity Date for the Note is hereby extended until April 23, 2029 (the "**Extension Period**").

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.<u>Monthly</u><u> </u><u>Payment Term(s) on Note During</u><u> </u><u>Extension Period</u>. Beginning in April 2026, on the 20th day of each calendar month (or the next Trading Day if a weekend or holiday) during the Extension Period, Borrower will calculate a number of shares of common stock equal to $1,000,000.00 (the "**Monthly Payment Amount**") divided by the lower of: (a) the immediately preceding Closing Trade Price, and (b) the average of the five (5) previous Closing Trade Prices (the "**Monthly Payment Shares**"). Within two (2) Trading Days of the applicable calculation date, Borrower will request that its transfer agent, Computershare, issue the calculated shares to Lender, and deliver such shares within four (4) Trading Days of the applicable calculation date (provided that Lender has delivered all applicable documentation to Computershare). In the event Borrower's common stock is either not trading on its principal market or is not available for immediate resell by Lender on the applicable calculation date and delivery date, then the Monthly Payment Amount must be paid to Lender in cash within fifteen

(15) days of the date the share issuance was due to Lender.

------

For the avoidance of doubt, Chicago Venture Partners ("**CVP**") currently holds two notes with Borrower – one in the name of Uptown Capital, LLC and another in the name of Streeterville Capital, LLC – and the Monthly Payment Amount will accrue and be applicable to one of the two notes on a monthly basis. CVP may, at its discretion, choose which of the two notes it would like to apply the Monthly Payment Amount to on a month-by-month basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.<u>Interest</u><u> </u><u>Rate</u>. During the Extension Period, the interest rate on the Note will decrease to five percent (5%).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5.<u>Failure</u><u> </u><u>to</u><u> </u><u>Make</u><u> </u><u>a</u><u> </u><u>Monthly</u><u> </u><u>Payment</u>. In the event Borrower fails to timely make a Monthly Payment (whether in cash or by delivery of Monthly Delivery Shares, as applicable), recourse to Lender will be as follows (i) in the first event of any missed payment/issuance, Borrower will have five (5) business days to cure the default; (ii) for any default thereafter, or in the event the first default is not timely cured: (a) the Extension Period will immediately terminate, (b) the Note will become immediately due and payable in full, (c) Default Interest will begin accruing on the Note, and (d) the difference between the interest accrued during the Extension Period at the reduced interest rate and the amount that would have accrued at the original ten percent (10%) interest rate during the Extension Period will automatically be added to the Outstanding Balance.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;6.<u>Representations</u><u> </u><u>and</u><u> </u><u>Warranties</u>. Each party, for itself, and for its affiliates, successors and assigns, hereby acknowledges, represents, warrants and agrees as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)Each of the parties has full power and authority to enter into this Amendment and to incur and perform all obligations and covenants contained herein, all of which have been duly authorized by all proper and necessary action. No consent, approval, filing or registration with or notice to any governmental authority is required as a condition to the validity of this Amendment or the performance of any of the obligations of the parties hereunder.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)Borrower represents that there is no fact known to Borrower or which should be known to Borrower which Borrower has not disclosed to Lender on or prior to the date of this Amendment which would or could materially and adversely affect the understanding of Lender expressed in this Amendment or any representation, warranty, or recital contained in this Amendment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)Except as expressly set forth in this Amendment, Borrower acknowledges and agrees that neither the execution and delivery of this Amendment nor any of the terms, provisions, covenants, or agreements contained in this Amendment shall in any manner release, impair, lessen, modify, waive, or otherwise affect the liability and obligations of Borrower under the terms of the Transaction Documents.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d)As of the effective date of this Amendment, Borrower has no known defenses against Lender, directly or indirectly, arising out of, based upon, or in any manner connected with, the transactions contemplated, which occurred, existed, was taken, permitted, or begun prior to the effective date of this Amendment and occurred, existed, was taken, permitted or begun in accordance with, pursuant to, or by virtue of any of the terms or conditions of the

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Transaction Documents. To the extent any such defenses existed as of the effective date of this Amendment, such defenses are hereby waived, discharged, and released. Borrower hereby acknowledges and agrees that the execution of this Amendment by Lender shall not constitute an acknowledgment of or admission by Lender of the existence of any claims or of liability for any matter or precedent upon which any claim or liability may be asserted.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e)Each of the parties represents and warrants that as of the date hereof no Events of Default or other material breaches exist under the Transaction Documents or have occurred prior to the date hereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;7.<u>Certain</u><u> </u><u>Acknowledgments</u>. Each of the parties acknowledges and agrees that no property or cash consideration of any kind whatsoever has been or shall be given by Lender to Borrower in connection with the Extension or any other amendment to the Note granted herein.

8<u>Other</u><u> </u><u>Terms</u><u> </u><u>Unchanged</u>. The Note, as amended by this Amendment and the Prior Amendment, remains and continues in full force and effect, constitutes legal, valid, and binding obligations of each of the parties, and is in all respects agreed to, ratified, and confirmed. Any reference to the Note after the date of this Amendment is deemed to be a reference to the Note as amended by this Amendment. If there is a conflict between the terms of this Amendment, the Prior Amendment, and the Note, the terms of this Amendment shall control. No forbearance or waiver may be implied by this Amendment. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver of, or as an amendment to, any right, power, or remedy of Lender under the Note, as in effect prior to the date hereof. For the avoidance of doubt, this Amendment shall be subject to the governing law, venue, and Arbitration Provisions, as set forth in the Note.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;9.<u>No</u><u> </u><u>Reliance</u>. Borrower acknowledges and agrees that neither Lender nor any of its officers, directors, members, managers, equity holders, representatives, or agents has made any representations or warranties to Borrower or any of its agents, representatives, officers, directors, or employees except as expressly set forth in this Amendment and the Transaction Documents and, in making its decision to enter into the transactions contemplated by this Amendment, Borrower is not relying on any representation, warranty, covenant, or promise of Lender or its officers, directors, members, managers, equity holders, agents or representatives other than as set forth in this Amendment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;10.<u>Counterparts</u>. This Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall constitute one

instrument. The parties hereto confirm that any electronic copy of another party's executed counterpart of this Amendment (or such party's signature page thereof) will be deemed to be an executed original thereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;11.<u>Further Assurances</u>. Each party shall do and perform or cause to be done and performed, all such further acts and things, and shall execute and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to carry out the intent and accomplish the purposes of this Amendment and the consummation of the transactions contemplated hereby.

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*[Remainder of page intentionally left blank]*

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IN WITNESS WHEREOF, the undersigned have executed this Amendment as of the date

above.

#### LENDER:
Uptown Capital, LLC

By: <u>/s/ John M. Fife</u> John M. Fife, President

#### BORROWER:
CytoDyn, Inc.

By:<u>/s/ Robert E. Hoffman</u> <sup>Name:</sup><u> </u><u>Robert Hoffman</u> 

<sup>Title:</sup> <u> </u><u>CFO</u> 

*[Signature Page to Amendment #2 to Secured Convertible Promissory Note]*

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## Exhibit 31.1

**Exhibit 31.1**

**Certification of Principal Executive Officer**

I, Jacob Lalezari, certify that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.&nbsp;&nbsp;&nbsp;&nbsp; I have reviewed this Quarterly Report on Form 10-Q of CytoDyn Inc.;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.&nbsp;&nbsp;&nbsp;&nbsp; Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.&nbsp;&nbsp;&nbsp;&nbsp; Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the Registrant as of, and for, the periods presented in this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.&nbsp;&nbsp;&nbsp;&nbsp; I am responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the Registrant and have:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the Registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this quarterly report is being prepared;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;b.&nbsp;&nbsp;&nbsp;&nbsp; designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;c.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;evaluated the effectiveness of the Registrant's disclosure controls and procedures and presented in this quarterly report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report, based on such evaluation; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;d.&nbsp;&nbsp;&nbsp;&nbsp; disclosed in this report any change in the Registrant's internal control over financial reporting that occurred during the registrant's most-recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the Registrant's internal control over financial reporting; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5.&nbsp;&nbsp;&nbsp;&nbsp; I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the Registrant's auditors and the audit committee of the Registrant's board of directors (or persons performing the equivalent functions):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the Registrant's ability to record, process, summarize and report financial information; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;b.&nbsp;&nbsp;&nbsp;&nbsp; any fraud, whether or not material, that involves management or other employees who have a significant role in the Registrant's internal control over financial reporting.

---

| | |
|:---|:---|
| Date: April 8, 2026 | /s/ Jacob Lalezari |
|  | Jacob Lalezari |
|  | Chief Executive Officer |

---

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## Exhibit 31.2

**Exhibit 31.2**

**Certification of Chief Financial Officer**

I, Robert E. Hoffman, certify that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.&nbsp;&nbsp;&nbsp;&nbsp; I have reviewed this Quarterly Report on Form 10-Q of CytoDyn Inc.;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.&nbsp;&nbsp;&nbsp;&nbsp; Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.&nbsp;&nbsp;&nbsp;&nbsp; Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the Registrant as of, and for, the periods presented in this report;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.&nbsp;&nbsp;&nbsp;&nbsp; The Registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the Registrant and have:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the Registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this quarterly report is being prepared;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;b.&nbsp;&nbsp;&nbsp;&nbsp; designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;c.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;evaluated the effectiveness of the Registrant's disclosure controls and procedures and presented in this quarterly report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report, based on such evaluation; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;d.&nbsp;&nbsp;&nbsp;&nbsp; disclosed in this report any change in the Registrant's internal control over financial reporting that occurred during the registrant's most-recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the Registrant's internal control over financial reporting; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5.&nbsp;&nbsp;&nbsp;&nbsp; The Registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the Registrant's auditors and the audit committee of the Registrant's board of directors (or persons performing the equivalent functions):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the Registrant's ability to record, process, summarize and report financial information; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;b.&nbsp;&nbsp;&nbsp;&nbsp; any fraud, whether or not material, that involves management or other employees who have a significant role in the Registrant's internal control over financial reporting.

---

| | |
|:---|:---|
| Date: April 8, 2026 | /s/ Robert E. Hoffman |
|  | Robert E. Hoffman |
|  | Chief Financial Officer  |

---

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## Ex-32

**Exhibit 32**

**CERTIFICATION PURSUANT TO** 

**18 U.S.C. SECTION 1350**

In connection with the Quarterly Report of CytoDyn Inc. (the "Company") on Form 10-Q for the fiscal quarter ended February 28, 2026, as filed with the Securities and Exchange Commission on the date hereof (the "Report"), the undersigned certify, pursuant to 18 U.S.C. Section 1350, that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;&nbsp;&nbsp;&nbsp; The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;&nbsp;&nbsp;&nbsp; The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

---

| | |
|:---|:---|
| /s/ Jacob Lalezari | /s/ Robert E. Hoffman |
| Jacob Lalezari | &nbsp;&nbsp;Robert E. Hoffman |
| Chief Executive Officer | &nbsp;&nbsp;Chief Financial Officer |
| Date: April 8, 2026 | &nbsp;&nbsp;Date: April 8, 2026 |

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A signed original of this written statement required by Section 906 has been provided to CytoDyn Inc. and will be retained by CytoDyn Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

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