# EDGAR Filing Document

**Accession Number:** 0001552740
**File Stem:** 0000940400-26-020383
**Filing Date:** 2026-5
**Character Count:** 20881
**Document Hash:** 8ad35566604ff502ae28b1ed79f38cbf
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000940400-26-020383.hdr.sgml**: 20260521

**ACCESSION NUMBER**: 0000940400-26-020383

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260521

**DATE AS OF CHANGE**: 20260521

**PERIOD START**: 20260331

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIRST TRUST EXCHANGE-TRADED FUND VI
- **CENTRAL INDEX KEY:** 0001552740

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MA

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-22717
- **FILM NUMBER:** 261007588

**BUSINESS ADDRESS:**
- **STREET 1:** 120 EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187
- **BUSINESS PHONE:** 630-765-8000

**MAIL ADDRESS:**
- **STREET 1:** 120 EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187

## Series and Classes Contracts Data

### First Trust Indxx Medical Devices ETF (Series ID: S000071976)

| Class ID   | Class Name                            | Ticker Symbol   |
|:---|:---|:---|
| C000227613 | First Trust Indxx Medical Devices ETF | MDEV            |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** First Trust Exchange-Traded Fund VI

- **b. Investment Company Act file number:** 811-22717

- **c. CIK number of Registrant:** 0001552740

- **d. LEI of Registrant:** 549300ZLB3EUU3H8NE60

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 120 East Liberty Drive

  - **City:** Wheaton

  - **State:** IL

  - **Foreign country:** US

  - **Zip / Postal Code:** 60187

  - **Telephone number:** 630-765-8000

**Item A.2. Information about the Series.**

- **a. Name of Series:** First Trust Indxx Medical Devices ETF

- **b. EDGAR series identifier (if any):** S000071976

- **c. LEI of Series:** 549300I7ZP4IRE34QB73

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-03-31

- **b. Date as of which information is reported:** 2026-03-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $1907149.89

**Total Liabilities:** $1155.41

**Net Assets:** $1905994.48

**Cash Not Reported:** $392.10

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000227613 | -0.67%               | 0.29%                | -9.06%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $0.00                    | $-12603.14                                 |
| Month 2  | $-44.90                  | $6240.81                                   |
| Month 3  | $37979.76                | $-230834.51                                |

### Schedule of Portfolio Investments

| Name                                      | Title                                               | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Insulet Corporation                       | Insulet Corporation COM                             | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |       132 | NS      | $27698.88     | 1.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Steris PLC                                | Steris PLC SHS USD                                  | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | IE        |       176 | NS      | $38918.88     | 2.04%             |  |  |  | No            |                  1 | On Loan: No      |
| DexCom Inc                                | DexCom Inc COM                                      | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |       637 | NS      | $40003.60     | 2.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Danaher Corporation                       | Danaher Corporation COM                             | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |       205 | NS      | $38868.00     | 2.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Sonova Holding AG                         | Sonova Holding AG CHF0.05 (REGD)                    | CUSIP: 000000000<br>LEI: 5299004A0QNX7FBNHS61 | Long             | EC               | CORP              | CH        |       153 | NS      | $34886.06     | 1.83%             |  |  |  | No            |                  2 | On Loan: No      |
| Masimo Corporation                        | Masimo Corporation COM                              | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |       287 | NS      | $51048.69     | 2.68%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc.                               | ResMed Inc. COM                                     | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |       152 | NS      | $34120.96     | 1.79%             |  |  |  | No            |                  1 | On Loan: No      |
| Boston Scientific Corporation             | Boston Scientific Corporation COM                   | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |       434 | NS      | $27233.50     | 1.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Sartorius Stedim Biotech SA               | Sartorius Stedim Biotech SA EUR0.20                 | CUSIP: 000000000<br>LEI: 52990006IVXY7GCSSR39 | Long             | EC               | CORP              | FR        |       191 | NS      | $37199.77     | 1.95%             |  |  |  | No            |                  2 | On Loan: No      |
| Siemens Healthineers AG                   | Siemens Healthineers AG NPV                         | CUSIP: 000000000<br>LEI: 529900QBVWXMWANH7H45 | Long             | EC               | CORP              | DE        |       758 | NS      | $32341.02     | 1.70%             |  |  |  | No            |                  2 | On Loan: No      |
| Olympus Corp.                             | Olympus Corp. NPV                                   | CUSIP: 000000000<br>LEI: 5299000Y52IFDI1I2A21 | Long             | EC               | CORP              | JP        |      3440 | NS      | $32774.01     | 1.72%             |  |  |  | No            |                  2 | On Loan: No      |
| Sysmex Corp.                              | Sysmex Corp. NPV                                    | CUSIP: 000000000<br>LEI: 5299001ZO4CKWACMZI55 | Long             | EC               | CORP              | JP        |      3334 | NS      | $29075.44     | 1.53%             |  |  |  | No            |                  2 | On Loan: No      |
| Straumann Holding AG                      | Straumann Holding AG CHF0.01 (REGD) (POST SPLIT)    | CUSIP: 000000000<br>LEI: 50670046ML5FVIM60Z37 | Long             | EC               | CORP              | CH        |       383 | NS      | $40070.66     | 2.10%             |  |  |  | No            |                  2 | On Loan: No      |
| Zimmer Biomet Holdings Inc                | Zimmer Biomet Holdings Inc COM                      | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |       438 | NS      | $39603.96     | 2.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton, Dickinson and Company             | Becton, Dickinson and Company COM                   | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |       222 | NS      | $34905.06     | 1.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corporation                        | Waters Corporation COM                              | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |       155 | NS      | $46159.00     | 2.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Med Inc                            | Globus Med Inc CL A                                 | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |       733 | NS      | $63155.28     | 3.31%             |  |  |  | No            |                  1 | On Loan: No      |
| Abbott Laboratories                       | Abbott Laboratories COM                             | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |       313 | NS      | $32135.71     | 1.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc.                   | Intuitive Surgical Inc. COM NEW                     | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |        96 | NS      | $44255.04     | 2.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc              | Thermo Fisher Scientific Inc COM                    | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |        79 | NS      | $38830.87     | 2.04%             |  |  |  | No            |                  1 | On Loan: No      |
| WuXi AppTec Co Ltd.                       | WuXi AppTec Co Ltd. CNY1 H                          | CUSIP: 000000000<br>LEI: 254900OEPQLZSPLN9175 | Long             | EC               | CORP              | CN        |      2885 | NS      | $44185.06     | 2.32%             |  |  |  | No            |                  2 | On Loan: No      |
| Koninklijke Philips NV                    | Koninklijke Philips NV EUR0.20                      | CUSIP: 000000000<br>LEI: H1FJE8H61JGM1JSGM897 | Long             | EC               | CORP              | NL        |      1510 | NS      | $41302.07     | 2.17%             |  |  |  | No            |                  2 | On Loan: No      |
| Penumbra Inc.                             | Penumbra Inc. COM                                   | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |       159 | NS      | $52210.83     | 2.74%             |  |  |  | No            |                  1 | On Loan: No      |
| Cochlear Ltd                              | Cochlear Ltd ORD NPV                                | CUSIP: 000000000<br>LEI: 5493001OLLWY8KV5UC08 | Long             | EC               | CORP              | AU        |       223 | NS      | $26240.57     | 1.38%             |  |  |  | No            |                  2 | On Loan: No      |
| Merit Medical Systems Inc.                | Merit Medical Systems Inc. COM                      | CUSIP: 589889104<br>LEI: 549300OYTY138SP2CE83 | Long             | EC               | CORP              | US        |       525 | NS      | $36188.25     | 1.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc.                     | Align Technology Inc. COM                           | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |       330 | NS      | $56571.90     | 2.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Dreyfus Government Cash Management Funds  | Dreyfus Government Cash Management Funds SH BEN INT | CUSIP: 262006208<br>LEI: 549300F7IDB6WRO7VJ11 | Long             | STIV             | RF                | US        |      2149 | NS      | $2149.18      | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Demant A/S                                | Demant A/S DKK0.20                                  | CUSIP: 000000000<br>LEI: 213800RM6L9LN78BVA56 | Long             | EC               | CORP              | DK        |      1174 | NS      | $35576.35     | 1.87%             |  |  |  | No            |                  2 | On Loan: No      |
| FISHER & PAYKEL HEALTHCARE CORP LTD       | Fisher & Paykel Healthcare Corp Ltd. NPV            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | NZ        |      1992 | NS      | $43193.49     | 2.27%             |  |  |  | No            |                  2 | On Loan: No      |
| Carl Zeiss Meditec AG                     | Carl Zeiss Meditec AG NPV                           | CUSIP: 000000000<br>LEI: 529900GRL4MZ8NMOOK95 | Long             | EC               | CORP              | DE        |       837 | NS      | $24057.90     | 1.26%             |  |  |  | No            |                  2 | On Loan: No      |
| Revvity Inc                               | Revvity Inc COM                                     | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |       470 | NS      | $41176.70     | 2.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Amplifon S.p.A.                           | Amplifon S.p.A. EUR0.02                             | CUSIP: 000000000<br>LEI: ZYXJDNVM2JI3VBM8G556 | Long             | EC               | CORP              | IT        |      2423 | NS      | $26732.60     | 1.40%             |  |  |  | No            |                  2 | On Loan: No      |
| West Pharmaceutical Services Incorporated | West Pharmaceutical Services Incorporated COM       | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |       158 | NS      | $39601.12     | 2.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Teleflex Incorporated                     | Teleflex Incorporated COM                           | CUSIP: 879369106<br>LEI: UUL85LWXB4NGSWWXIQ25 | Long             | EC               | CORP              | US        |       347 | NS      | $41504.67     | 2.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Baxter International, Inc.                | Baxter International, Inc. COM                      | CUSIP: 071813109<br>LEI: J5OIVXX3P24RJRW5CK77 | Long             | EC               | CORP              | US        |      1889 | NS      | $31735.20     | 1.67%             |  |  |  | No            |                  1 | On Loan: No      |
| Edwards Lifesciences Corporation          | Edwards Lifesciences Corporation COM                | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |       561 | NS      | $44924.88     | 2.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Smith & Nephew PLC                        | Smith & Nephew PLC ORD USD0.20                      | CUSIP: 000000000<br>LEI: 213800ZTMDN8S67S1H61 | Long             | EC               | CORP              | GB        |      2352 | NS      | $37264.89     | 1.96%             |  |  |  | No            |                  2 | On Loan: No      |
| Medtronic PLC                             | Medtronic PLC SHS                                   | CUSIP: 000000000<br>LEI: 549300GX3ZBSQWUXY261 | Long             | EC               | CORP              | IE        |       434 | NS      | $37606.10     | 1.97%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMerieux SA                             | BioMerieux SA NPV                                   | CUSIP: 000000000<br>LEI: 549300AK8Y0LBIQ4T071 | Long             | EC               | CORP              | FR        |       312 | NS      | $33332.31     | 1.75%             |  |  |  | No            |                  2 | On Loan: No      |
| HOYA Corp.                                | HOYA Corp. NPV                                      | CUSIP: 000000000<br>LEI: 353800X4VR3BHEUCJB42 | Long             | EC               | CORP              | JP        |       294 | NS      | $50967.97     | 2.67%             |  |  |  | No            |                  2 | On Loan: No      |
| Bio-Rad Laboratories, Inc.                | Bio-Rad Laboratories, Inc. CL A                     | CUSIP: 090572207<br>LEI: 549300ZC1GPV35XYDK53 | Long             | EC               | CORP              | US        |       139 | NS      | $38746.25     | 2.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Coloplast AS                              | Coloplast AS SER'B'DKK1                             | CUSIP: 000000000<br>LEI: 529900NN7SOJ5QG82X67 | Long             | EC               | CORP              | DK        |       473 | NS      | $32220.26     | 1.69%             |  |  |  | No            |                  2 | On Loan: No      |
| Alcon AG                                  | Alcon AG CHF0.04                                    | CUSIP: 000000000<br>LEI: 549300LDT5AP8S0NBM78 | Long             | EC               | CORP              | CH        |       574 | NS      | $43388.79     | 2.28%             |  |  |  | No            |                  2 | On Loan: No      |
| Stryker Corporation                       | Stryker Corporation COM                             | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |       114 | NS      | $37459.26     | 1.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                               | Hologic Inc COM                                     | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |       612 | NS      | $46261.08     | 2.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc.                 | Agilent Technologies Inc. COM                       | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |       303 | NS      | $34535.94     | 1.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Mettler-Toledo International Inc          | Mettler-Toledo International Inc COM                | CUSIP: 592688105<br>LEI: 5493000BD5GJNUDIUG10 | Long             | EC               | CORP              | US        |        33 | NS      | $41619.60     | 2.18%             |  |  |  | No            |                  1 | On Loan: No      |
| The Cooper Companies, Inc.                | The Cooper Companies, Inc. COM                      | CUSIP: 216648501<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |       606 | NS      | $43329.00     | 2.27%             |  |  |  | No            |                  1 | On Loan: No      |
| GE Healthcare Technologies Inc.           | GE Healthcare Technologies Inc. COMMON STOCK        | CUSIP: 36266G107<br>LEI: 549300OI9J7XOWZMUN85 | Long             | EC               | CORP              | US        |       584 | NS      | $41569.12     | 2.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Terumo Corp.                              | Terumo Corp. NPV                                    | CUSIP: 000000000<br>LEI: 353800JX1R4582QVK932 | Long             | EC               | CORP              | JP        |      2560 | NS      | $34392.98     | 1.80%             |  |  |  | No            |                  2 | On Loan: No      |

### Signature

**Date Signed:** 2026-05-21

**Name of Applicant:** First Trust Exchange-Traded Fund VI

**Signature:** Derek Maltbie

**Name of Signer:** Derek Maltbie

**Title:** Treasurer, Chief Financial Officer and Chief Accounting Officer