# EDGAR Filing Document

**Accession Number:** 0001651308
**File Stem:** 0001628280-25-049821
**Filing Date:** 2025-11
**Character Count:** 42979
**Document Hash:** cf82302021689fb014db5c22b85a2a8e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001628280-25-049821.hdr.sgml**: 20251106

**ACCESSION NUMBER**: 0001628280-25-049821

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 14

**CONFORMED PERIOD OF REPORT**: 20251106

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20251106

**DATE AS OF CHANGE**: 20251106

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** BeOne Medicines Ltd.
- **CENTRAL INDEX KEY:** 0001651308
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 981209416
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-37686
- **FILM NUMBER:** 251455924

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** C/O BEONE MEDICINES I GMBH
- **STREET 2:** AESCHENGRABEN 27, 21ST FLOOR
- **CITY:** BASEL
- **PROVINCE COUNTRY:** V8
- **ZIP:** 4051
- **BUSINESS PHONE:** 41-616851900

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** C/O BEONE MEDICINES I GMBH
- **STREET 2:** AESCHENGRABEN 27, 21ST FLOOR
- **CITY:** BASEL
- **PROVINCE COUNTRY:** V8
- **ZIP:** 4051

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** BeiGene, Ltd.
- **DATE OF NAME CHANGE:** 20150819

?xml version='1.0' encoding='ASCII'? bgne-20251106

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**_____________________**

**Form 8-K** 

**_________________________**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934**

Date of Report (Date of earliest event Reported): November 6, 2025

**BEONE MEDICINES LTD.** 

**(Exact Name of Registrant as Specified in Charter)**

---

| | | |
|:---|:---|:---|
| **Switzerland** | **001-37686** | **98-1209416** |
| (State or Other Jurisdiction of Incorporation) | (Commission File Number) | (I.R.S. Employer Identification Number) |

---

c/o BeOne Medicines I GmbH

Aeschengraben 27

Basel 4051

Switzerland

(Address of Principal Executive Offices) (Zip Code)

**+41 61 685 19 00** 

(Registrant's telephone number, including area code)

**N/A**

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| **Title of each class** | **Trading Symbol(s)** | **Name of each exchange on which registered** |
| **American Depositary Shares, each representing 13 Ordinary Shares, par value $0.0001 per share** | **ONC** | **The Nasdaq Global Select Market** |
| **Ordinary Shares, par value $0.0001 per share\*** | **06160** | **The Stock Exchange of Hong Kong Limited** |

---

\*Included in connection with the registration of the American Depositary Shares with the Securities and Exchange Commission. The ordinary shares are not listed for trading in the United States but are listed for trading on The Stock Exchange of Hong Kong Limited.

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2). Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. □

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**Item 2.02. Results of Operations and Financial Condition.**

On November 6, 2025, BeOne Medicines Ltd. (the "Company") announced its financial results for the three months ended September 30, 2025. A copy of the press release is attached hereto as Exhibit 99.1 to this Current Report on Form 8-K.

**Item 9.01. Financial Statements and Exhibits.**

(d) <u>Exhibits</u>.

---

| | |
|:---|:---|
| **Exhibit No.** | **Description** |
| 99.1 | Press release titled "BeOne Medicines Announces Third Quarter 2025 Financial Results and Business Updates" issued by BeOne Medicines Ltd. on November 6, 2025 |
| 104 | The cover page from this Current Report on Form 8-K, formatted in Inline XBRL |

---

The portions of the press release set forth under Item 2.02 of this Current Report on Form 8-K are being furnished and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall they be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended or the Exchange Act, except as expressly set forth by specific reference in such filing.

------

**Exhibit Index** 

---

| | |
|:---|:---|
| **Exhibit No.** | **Description** |
| 99.1 | <u>[Press release titled "BeOne Medicines Announces](exhibit991-q32025earningsr.htm)[Third](exhibit991-q32025earningsr.htm)[Quarter 2025 Financial Results and Business Updates" issued by BeOne Medicines Ltd. on](exhibit991-q32025earningsr.htm)[November](exhibit991-q32025earningsr.htm)[6, 2025](exhibit991-q32025earningsr.htm)</u> |
| 104 | The cover page from this Current Report on Form 8-K, formatted in Inline XBRL |

---

------

**SIGNATURE**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
| | **BEONE MEDICINES LTD.** | **BEONE MEDICINES LTD.** |
| Date: November 6, 2025 | By: | /s/ Chan Lee |
|  | Name: | Chan Lee |
|  | Title: | Senior Vice President, General Counsel |

---

## Exhibit 99.1

---

| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

---

**BeOne Medicines Announces Third Quarter 2025 Financial Results and Business Updates**

*• Third quarter total revenues increased 41% to $1.4 billion versus third quarter 2024*

*• Global BRUKINSA*<sup>®</sup> *(zanubrutinib) revenues increased 51% to $1.0 billion versus third quarter 2024*

*• Diluted GAAP Earnings per American Depository Share (ADS) of $1.09, non-GAAP diluted Earnings per ADS of $2.65*

*• 47 abstracts accepted at American Society of Hematology (ASH) Annual Meeting*

SAN CARLOS, Calif. – November 6, 2025 – BeOne Medicines Ltd. (NASDAQ: ONC; HKEX: 06160; SSE: 688235), a global oncology company, today announced financial results and corporate updates from the third quarter of 2025.

"These strong financial results reinforce our position as a global oncology leader with exceptional topline growth and a strong balance sheet," said John V. Oyler, Co-Founder, Chairman and CEO at BeOne. "BRUKINSA is now the global revenue leader in the BTKi class, supported by long-term efficacy and safety data and a growing body of evidence reinforcing its scientific hypothesis of sustained BTK inhibition. Our late-stage hematology portfolio continues to advance with sonrotoclax, a potentially best-in-class BCL2 inhibitor that has demonstrated impressive clinical results, and our BTK CDAC BGB-16673, further strengthening our leadership in B cell malignancies, including CLL. With one of the most promising oncology pipelines in the industry, we are poised to deliver multiple data and regulatory milestones that will drive long-term value."

(Amounts in thousands of U.S. dollars and unaudited)

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| | **Three Months Ended September 30,** | **Three Months Ended September 30,** | | **Nine Months Ended September 30,** | **Nine Months Ended September 30,** | |
| | **2025** | **2024** |<br>**% Change** | **2025** | **2024** |<br>**% Change** |
| Net product revenues | $1395013 | $993447 | 40% | $3805619 | $2661511 | 43% |
| Other revenue | $17271 | $8152 | 112% | $39244 | $20906 | 88% |
| Total revenue | $1412284 | $1001599 | 41% | $3844863 | $2682417 | 43% |
| GAAP income (loss) from operations | $163114 | $(120265) | 236% | $262101 | $(488774) | 154% |
| Adjusted income (loss) from operations\* | $341184 | $65630 | 420% | $755486 | $(33247) | 2372% |
| GAAP net income (loss) | $124841 | $(121350) | 203% | $220431 | $(492905) | 145% |
| Adjusted net income (loss)\* | $303663 | $51582 | 489% | $692622 | $(71020) | 1075% |
| GAAP basic EPS per ADS | $1.13 | $(1.15) | 198% | $2.03 | $(4.71) | 143% |
| Adjusted basic EPS per ADS\* | $2.76 | $0.49 | 463% | $6.38 | $(0.68) | 1038% |
| GAAP diluted EPS per ADS | $1.09 | $(1.15) | 195% | $1.96 | $(4.71) | 142% |
| Adjusted diluted EPS per ADS\* | $2.65 | $0.48 | 452% | $6.14 | $(0.68) | 1003% |
| Free Cash Flow\* | $354469 | $54714 | 548% | $561916 | $(615974) | 191% |

---

\* For an explanation of our use of non-GAAP financial measures refer to the "Note Regarding Use of Non-GAAP Financial Measures" section later in this press release and for a reconciliation of each non-GAAP financial measure to the most comparable GAAP measures, see the table at the end of this press release.

------

---

| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

---

**<u>Third Quarter 2025 Financial Results</u>**

**Revenue** for the third quarter of 2025 was $1.4 billion, compared to $1.0 billion in the prior-year period driven primarily by growth in BRUKINSA product sales in the U.S. and Europe.

**Product Revenue** totaled $1.4 billion for the third quarter of 2025 compared to $993 million in the prior-year period. The increase in product revenue was primarily attributable to increased sales of BRUKINSA. The U.S. continued to be the Company's largest market, with product revenue of $743 million compared to $504 million in the prior-year period. In-licensed products from Amgen and TEVIMBRA<sup>®</sup> (tislelizumab) also contributed to product revenue growth.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• U.S. sales of BRUKINSA totaled $739 million in the third quarter of 2025, representing growth of 47% over the prior-year period driven primarily by robust demand growth across all indications and modest benefit due to net pricing. BRUKINSA continues to maintain its leading new patient share across the BTKi class due to its differentiated, best-in-class clinical profile. BRUKINSA sales in Europe totaled $163 million in the third quarter of 2025, representing growth of 68% compared to the prior-year period, driven by increased market share across all major European markets, including Germany, Italy, Spain, France and the UK.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Sales of TEVIMBRA totaled $191 million in the third quarter of 2025, representing growth of 17% compared to the prior-year period.

**Gross Margin** as a percentage of global product sales for the third quarter of 2025 was 85.9% compared to 82.8% in the prior-year period on a GAAP basis. The gross margin percentage increased due to a proportionally higher sales mix of global BRUKINSA compared to other products in our portfolio. Gross margin also benefited from production productivity improvements for both BRUKINSA and TEVIMBRA. On an adjusted basis, which does not include depreciation and amortization, gross margin as a percentage of product sales increased to 86.3% for the third quarter of 2025, compared to 84.9% in the prior-year period.

**Operating Expenses**

The following table summarizes operating expenses for the third quarter of 2025:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| | **GAAP** | **GAAP** | | **Non-GAAP** | **Non-GAAP** | |
| **(unaudited, in thousands, except percentages)** | **Q3 2025** | **Q3 2024** |<br>**% Change** | **Q3 2025** | **Q3 2024** |<br>**% Change** |
| Research and development | $523662 | $496179 | 6% | $445904 | $405545 | 10% |
| Selling, general and administrative | $528998 | $455223 | 16% | $434484 | $380737 | 14% |
| Total operating expenses | $1052660 | $951402 | 11% | $880388 | $786282 | 12% |

---

The following table summarizes operating expenses for the year-to-date period ended September 30, 2025 and 2024:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| | **GAAP** | **GAAP** | | **Non-GAAP** | **Non-GAAP** | |
| **(unaudited, in thousands, except percentages)** | **Q3 YTD 2025** | **Q3 YTD 2024** |<br>**% Change** | **Q3 YTD 2025** | **Q3 YTD 2024** |<br>**% Change** |
| Research and development | $1530445 | $1411283 | 8% | $1311156 | $1193494 | 10% |
| Selling, general and administrative | $1526199 | $1326379 | 15% | $1271650 | $1116805 | 14% |
| Total operating expenses | $3056644 | $2737662 | 12% | $2582806 | $2310299 | 12% |

---

**Research and Development (R&D) Expenses** increased for the third quarter of 2025 compared to the prior-year period on both a GAAP and adjusted basis primarily due to advancing preclinical programs into the clinic and early clinical programs into late stage, and offset by lower development upfront and milestone fees. Upfront fees and milestone payments related to in-process R&D for in-licensed assets totaled $0.2 million and $5 million in the third quarter of 2025 and 2024, respectively.

**Selling, General and Administrative (SG&A) Expenses** increased for the third quarter of 2025 compared to the prior-year period on both a GAAP and adjusted basis due to continued investment in global commercial expansion, primarily in the U.S. and Europe. SG&A expenses as a percentage of product sales were 38% for the third quarter of 2025, compared to 46% in the prior-year period.

**Net Income/(Loss) and GAAP/Non-GAAP Earnings Per Share**

GAAP net income for the third quarter of 2025 was $125 million, an increase of $246 million over the prior-year period loss, primarily attributable to revenue growth and improved operating leverage.

------

---

| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

---

For the third quarter of 2025, basic and diluted earnings per share was $0.09 and $0.08 per share and $1.13 and $1.09 per American Depositary Share (ADS), respectively, compared to basic loss of $0.09 per share and $1.15 per ADS in the prior-year period.

**Free Cash Flow** for the third quarter of 2025 was $354 million, an increase of $300 million over the prior-year period.

For further details on BeOne's Third Quarter 2025 Financial Statements, please see BeOne's Quarterly Report on Form 10-Q for the third quarter of 2025 filed with the U.S. Securities and Exchange Commission.

**<u>Full Year 2025 Guidance</u>**

BeOne has updated its full year 2025 revenue and expense guidance. Guidance is summarized below:

---

| | | |
|:---|:---|:---|
| | **Prior FY 2025 Guidance**<sup>1</sup> | **Current FY 2025 Guidance**<sup>1</sup> |
| **Total Revenue** | $5.0 - $5.3B | $5.1 - $5.3B |
| **GAAP Operating Expenses<br>(R&D and SG&A)** | $4.1 - $4.4B | $4.1 - $4.3B |
| **GAAP Gross Margin %** | Mid to high -80% range | Unchanged |
| **GAAP Operating Income** | Positive FY 2025 | Unchanged |
| **Cash Flow** | Positive FY 2025 free<br>cash flow | Unchanged |

---

<sup>1</sup> Does not assume any potential new, material business development activity or unusual/non-recurring items. Assumes September 30, 2025, foreign exchange rates.

BeOne's total revenue guidance for full year 2025 of $5.1 billion to $5.3 billion includes expectations for strong revenue growth driven by BRUKINSA's U.S. leadership position and continued global expansion in both Europe and other important rest of world markets. Gross margin percentage is expected to be in the mid- to high-80% range due to mix and production efficiencies as compared to 2024. BeOne's guidance for combined operating expenses on a GAAP basis includes expectations of investment to support growth in both commercial and research at a pace that continues to deliver meaningful operating leverage. Non-GAAP operating expenses, which exclude costs related to share-based compensation, depreciation and amortization expense, are expected to track with GAAP operating expenses, with reconciling items unchanged from existing practice. Operating expense guidance does not assume any potential new, material business development activity or unusual/non-recurring items.

**<u>Third Quarter Business Highlights</u>**

**Core Marketed Products**

*BRUKINSA (zanubrutinib)* 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** Approved in 75 markets globally with reimbursement in 57 markets.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received European Commission (EC) approval of a film-coated tablet formulation of for all approved indications; launched tablet formulation in the U.S.

*TEVIMBRA (tislelizumab)*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Approved in 47 markets globally with reimbursement in 16 markets.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received EC approval in combination with platinum-containing chemotherapy as neoadjuvant treatment followed by TEVIMBRA monotherapy as adjuvant treatment for adult patients with resectable non-small cell lung cancer (NSCLC) at high risk of recurrence.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Achieved first subject enrolled in Phase 3 trial for subcutaneous formulation for the treatment of first-line gastric cancer (GC).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Achieved submission in Japan for the treatment of first-line GC.

------

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

---

**Select Clinical-Stage Programs**

*Hematology*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** Sonrotoclax (BCL2 inhibitor):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Received FDA Breakthrough Therapy Designation as a treatment for adult patients with relapsed or refractory (R/R) mantle cell lymphoma (MCL).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Completed enrollment of Phase 2 trial for the treatment of adult patients with R/R Waldenstrom's macroglobulinemia (WM), which is potentially registration enabling.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** BGB-16673 (BTK CDAC):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Achieved first subject enrolled in global Phase 3 head-to-head study versus noncovalent BTK inhibitor pirtobrutinib for the treatment of adult patients with R/R CLL.

*Breast/Gynecologic Cancers*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• BC-C9074 (B7-H4 ADC): Achieved proof-of-concept.

*Lung Cancer*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• BG-58067 (MTA-cooperative PRMT5 inhibitor): Achieved proof-of-concept.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Tarlatamab (AMG 757): Achieved first subject enrolled in global Phase 3 trial for the treatment of first-line extensive-stage small cell lung cancer.

*GI Cancers* 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• BGB-B2033 (GPC3x41BB bispecific antibody): Achieved proof-of-concept.

*Inflammation & Immunology*

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• BGB-45035 (IRAK4 CDAC):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Achieved proof-of-concept for target tissue degradation in healthy volunteers.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Achieved first subject enrolled in Phase 2 trial for the treatment of moderate to severe rheumatoid arthritis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• BGB-16673:Achieved first subject enrolled in Phase 1b trial for the treatment of chronic spontaneous urticaria.

------

---

| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

---

**Anticipated R&D Milestones**

---

| | | |
|:---|:---|:---|
| **Programs** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Milestones** | **Timing** |
| **BRUKINSA** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** Orphan Drug Designation and regulatory submission in Japan for the treatment of marginal zone lymphoma. | 1H 2026 |
| **TEVIMBRA** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** Anticipate Japan approval for the treatment of first-line gastric cancer. | 2H 2026 |
| **Hematology** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** Sonrotoclax (BCL2 inhibitor):  |  |
| **Hematology** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Initiate enrollment of Phase 3 trial in combination with BRUKINSA versus acalabrutinib+venetoclax (AV). | 1H 2026 |
| **Hematology** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Initiate enrollment in Phase 3 trial for the treatment of multiple myeloma. | 2H 2026 |
| **Hematology** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** BGB-16673 (BTK CDAC): |  |
|  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Data readout for potential accelerated approval submission for the treatment of R/R CLL. | 1H 2026 |
| **Breast/Gynecologic Cancers** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• BGB-43395 (CDK4 inhibitor):  |  |
| **Breast/Gynecologic Cancers** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Initiate Phase 3 trial for the treatment of first-line HR-positive, HER2-negative metastatic breast cancer. | 1H 2026 |
| **GI Cancers** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Zanidatamab (HER2-targeting bispecific antibody) for the treatment of first-line HER2-positive gastroesophageal adenocarcinoma:  |  |
|  | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Readout of primary progression-free survival data from Phase 3 trial (Herizon GEA-301) in collaboration with Zymeworks/Jazz. | 2H 2025 |
| **Inflammation and Immunology** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**•** BGB-45035 (IRAK4 CDAC): |  |
| **Inflammation and Immunology** | &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;◦ Initiate Phase 2 trial for the treatment of atopic dermatitis.  | 1H 2026 |

---

**Other Highlights**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Entered into an agreement with Royalty Pharma to sell royalty rights on the worldwide sales, excluding China, of Amgen's IMDELLTRA® (tarlatamab-dlle) for up to $950 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Announced Pharmacyclics' decision not to appeal a U.S. Patent and Trademark Office Final Written Decision invalidating all claims of Pharmacyclics' U.S. Patent No. 11,672,803 related to BRUKINSA, which fully resolved the patent infringement lawsuit brought by Pharmacyclics.

**<u>Conference Call and Webcast</u>**

The Company's earnings conference call for the third quarter 2025 will be broadcast via webcast at 8:00 a.m. ET on Thursday, November 6, 2025, and will be accessible through the Investors section of BeOne's website at www.beonemedicines.com. Supplemental information in the form of a slide presentation and a replay of the webcast will also be available.

**<u>About BeOne</u>**

BeOne Medicines is a global oncology company domiciled in Switzerland that is discovering and developing innovative treatments that are more accessible to cancer patients worldwide. With a portfolio spanning hematology and solid tumors, BeOne is expediting development of its diverse pipeline of novel therapeutics through its internal capabilities and collaborations. With a growing global team of nearly 12,000 colleagues spanning six continents, the Company is committed to radically improving access to medicines for far more patients who need them.

To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X, Facebook and Instagram.

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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**<u>Forward-Looking Statements</u>**

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and other federal securities laws, including statements regarding: upcoming R&D milestones to be achieved by BeOne; the timing of clinical developments and data readouts; BeOne's expectations regarding continued global expansion and investment to support growth; the potential of sonrotoclax to be a best-in-class BCL2 inhibitor; BeOne's ability to deliver meaningful data and regulatory milestones that will drive long-term value; BeOne's future revenue, operating income, cash flow, free cash flow, operating expenses and gross margin percentage; and BeOne's plans, commitments, aspirations and goals under the caption "About BeOne". Actual results may differ materially from those indicated in the forward-looking statements as a result of various important factors, including BeOne's ability to demonstrate the efficacy and safety of its drug candidates; the clinical results for its drug candidates, which may not support further development or marketing approval; actions of regulatory agencies, which may affect the initiation, timing and progress of clinical trials and marketing approval; BeOne's ability to achieve commercial success for its marketed medicines and drug candidates, if approved; BeOne's ability to obtain and maintain protection of intellectual property for its medicines and technology; BeOne's reliance on third parties to conduct drug development, manufacturing, commercialization, and other services; BeOne's limited experience in obtaining regulatory approvals and commercializing pharmaceutical products; BeOne's ability to obtain additional funding for operations and to complete the development of its drug candidates and achieve and maintain profitability; and those risks more fully discussed in the section entitled "Risk Factors" in BeOne's most recent quarterly report on Form 10-Q, as well as discussions of potential risks, uncertainties, and other important factors in BeOne's subsequent filings with the U.S. Securities and Exchange Commission. All information in this press release is as of the date of this press release, and BeOne undertakes no duty to update such information unless required by law. BeOne's financial guidance is based on estimates and assumptions that are subject to significant uncertainties.

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| | |
|:---|:---|
| **Investor Contact** | **Media Contact** |
| Liza Heapes | Kyle Blankenship |
| +1 857-302-5663 | +1 667-351-5176 |
| ir@beonemed.com | media@beonemed.com |

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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**Condensed Consolidated Statements of Operations (U.S. GAAP)**

(Amounts in thousands of U.S. dollars, except for shares, American Depositary Shares (ADSs), per share and per ADS data)

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| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended**<br>**September 30,** | **Three Months Ended**<br>**September 30,** | **Nine Months Ended**<br>**September 30,** | **Nine Months Ended**<br>**September 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| | **(Unaudited)** | **(Unaudited)** | **(Unaudited)** | **(Unaudited)** |
| Revenues |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Product revenue, net | $1395013 | $993447 | $3805619 | $2661511 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other revenue | 17271 | 8152 | 39244 | 20906 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total revenues | 1412284 | 1001599 | 3844863 | 2682417 |
| &nbsp;&nbsp;&nbsp;&nbsp;Cost of sales - products | 196510 | 170462 | 526118 | 433529 |
| Gross profit | 1215774 | 831137 | 3318745 | 2248888 |
| Operating expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development | 523662 | 496179 | 1530445 | 1411283 |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative | 528998 | 455223 | 1526199 | 1326379 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | 1052660 | 951402 | 3056644 | 2737662 |
| Income (loss) from operations | 163114 | (120265) | 262101 | (488774) |
| &nbsp;&nbsp;&nbsp;&nbsp;Interest income, net | 3029 | 10643 | 12374 | 40028 |
| &nbsp;&nbsp;&nbsp;&nbsp;Other income (expense), net | (18979) | 11318 | (6862) | 1096 |
| Income (loss) before income taxes | 147164 | (98304) | 267613 | (447650) |
| Income tax expense | 22323 | 23046 | 47182 | 45255 |
| Net income (loss) | $124841 | $(121350) | 220431 | (492905) |
| Earnings (loss) per share |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $0.09 | $(0.09) | 0.16 | (0.36) |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $0.08 | $(0.09) | 0.15 | (0.36) |
| Weighted-average shares outstanding—basic | 1432801699 | 1376751873 | 1410497062 | 1361216763 |
| Weighted-average shares outstanding—diluted | 1488750354 | 1376751873 | 1465535004 | 1361216763 |
| Earnings (loss) per American Depositary Share ("ADS") |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $1.13 | $(1.15) | 2.03 | (4.71) |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $1.09 | $(1.15) | 1.96 | (4.71) |
| Weighted-average ADSs outstanding—basic | 110215515 | 105903990 | 108499774 | 104708982 |
| Weighted-average ADSs outstanding—diluted | 114519258 | 105903990 | 112733462 | 104708982 |

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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**Select Condensed Consolidated Balance Sheet Data (U.S. GAAP)**

(Amounts in thousands of U.S. Dollars)

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| | | |
|:---|:---|:---|
| | **As of** | **As of** |
| | **September 30,**<br>**2025** | **December 31,**<br>**2024** |
| | **(unaudited)** | **(audited)** |
| **Assets:** |  |  |
| Cash, cash equivalents and restricted cash | $4110542 | $2638747 |
| Accounts receivable, net | 863281 | 676278 |
| Inventories | 531687 | 494986 |
| Property, plant and equipment, net | 1628114 | 1578423 |
| Total assets | 7632586 | 5920910 |
| **Liabilities and equity:** |  |  |
| Accounts payable | 383676 | 404997 |
| Accrued expenses and other payables | 1001661 | 803713 |
| Royalty financing liability | 885000 |  |
| R&D cost share liability | 90596 | 165440 |
| Debt | 952867 | 1018013 |
| Total liabilities | 3503260 | 2588688 |
| Total equity | $4129326 | $3332222 |

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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**Select Unaudited Condensed Consolidated Statements of Cash Flows (U.S. GAAP)**

(Amounts in thousands of U.S. Dollars)

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| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended**<br>**September 30,** | **Three Months Ended**<br>**September 30,** | **Nine Months Ended**<br>**September 30,** | **Nine Months Ended**<br>**September 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| | **(unaudited)** | **(unaudited)** | **(unaudited)** | **(unaudited)** |
| Cash, cash equivalents and restricted cash at beginning of period | $2786086 | $2617931 | $2638747 | $3185984 |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash provided by (used in) operating activities | 402553 | 188369 | 710233 | (215791) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash used in investing activities | (49274) | (133882) | (237820) | (454745) |
| &nbsp;&nbsp;&nbsp;&nbsp;Net cash provided by financing activities | 961272 | 12662 | 962520 | 197972 |
| &nbsp;&nbsp;&nbsp;&nbsp;Net effect of foreign exchange rate changes | 9905 | 28348 | 36862 | 8 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net increase (decrease) in cash, cash equivalents, and restricted cash | 1324456 | 95497 | 1471795 | (472556) |
| Cash, cash equivalents and restricted cash at end of period | $4110542 | $2713428 | $4110542 | $2713428 |

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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**Note Regarding Use of Non-GAAP Financial Measures**

BeOne provides certain non-GAAP financial measures, including Adjusted Operating Expenses, Adjusted Operating Loss, Adjusted Net Income, Adjusted Earnings Per Share and certain other non-GAAP income statement line items, each of which include adjustments to GAAP figures. These non-GAAP financial measures are intended to provide additional information on BeOne's operating performance. Adjustments to BeOne's GAAP figures exclude, as applicable, non-cash items such as share-based compensation, depreciation and amortization. Certain other special items or substantive events may also be included in the non-GAAP adjustments periodically when their magnitude is significant within the periods incurred. Non-GAAP adjustments are tax effected to the extent there is U.S. GAAP current tax expense. The Company currently records a valuation allowance on its net deferred tax assets, so there is no net impact recorded for deferred tax effects. BeOne maintains an established non-GAAP policy that guides the determination of what costs will be excluded in non-GAAP financial measures and the related protocols, controls and approval with respect to the use of such measures. BeOne believes that these non-GAAP financial measures, when considered together with the GAAP figures, can enhance an overall understanding of BeOne's operating performance. The non-GAAP financial measures are included with the intent of providing investors with a more complete understanding of BeOne's historical and expected financial results and trends and to facilitate comparisons between periods and with respect to projected information. In addition, these non-GAAP financial measures are among the indicators BeOne's management uses for planning and forecasting purposes and measuring BeOne's performance. These non-GAAP financial measures should be considered in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. The non-GAAP financial measures used by BeOne may be calculated differently from, and therefore may not be comparable to, non-GAAP financial measures used by other companies.

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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**RECONCILIATION OF SELECTED GAAP MEASURES TO NON-GAAP MEASURES**

(Amounts in thousands of U.S. Dollars)

(unaudited)

---

| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended** | **Three Months Ended** | **Nine Months Ended** | **Nine Months Ended** |
| | **September 30,** | **September 30,** | **September 30,** | **September 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| **Reconciliation of GAAP to adjusted cost of sales - products:** |  |  |  |  |
| GAAP cost of sales - products | $196510 | $170462 | $526118 | $433529 |
| Less: Depreciation | 4261 | 19589 | 10195 | 24618 |
| Less: Amortization of intangibles | 1537 | 1186 | 8459 | 3546 |
| Less: Other |  |  | 893 |  |
| Adjusted cost of sales - products | $190712 | $149687 | $506571 | $405365 |
| **Reconciliation of GAAP to adjusted research and development:** |  |  |  |  |
| GAAP research and development | $523662 | $496179 | $1530445 | $1411283 |
| Less: Share-based compensation cost | 58839 | 47670 | 164998 | 141121 |
| Less: Depreciation | 18919 | 42964 | 54291 | 76668 |
| Adjusted research and development | $445904 | $405545 | $1311156 | $1193494 |
| **Reconciliation of GAAP to adjusted selling, general and administrative:** |  |  |  |  |
| GAAP selling, general and administrative | $528998 | $455223 | $1526199 | $1326379 |
| Less: Share-based compensation cost | 81947 | 66933 | 221792 | 192890 |
| Less: Depreciation | 12550 | 7475 | 32712 | 16606 |
| Less: Amortization of intangibles | 17 | 78 | 45 | 78 |
| Adjusted selling, general and administrative | $434484 | $380737 | $1271650 | $1116805 |
| **Reconciliation of GAAP to adjusted operating expenses** |  |  |  |  |
| GAAP operating expenses | $1052660 | $951402 | $3056644 | $2737662 |
| Less: Share-based compensation cost | 140786 | 114603 | 386790 | 334011 |
| Less: Depreciation | 31469 | 50439 | 87003 | 93274 |
| Less: Amortization of intangibles | 17 | 78 | 45 | 78 |
| Adjusted operating expenses | $880388 | $786282 | $2582806 | $2310299 |
| **Reconciliation of GAAP to adjusted income (loss) from operations:** |  |  |  |  |
| GAAP income (loss) from operations | $163114 | $(120265) | $262101 | $(488774) |
| Plus: Share-based compensation cost | 140786 | 114603 | 386790 | 334011 |
| Plus: Depreciation | 35730 | 70028 | 97198 | 117892 |
| Plus: Amortization of intangibles | 1554 | 1264 | 8504 | 3624 |
| Plus: Other |  |  | 893 |  |
| Adjusted income (loss) from operations | $341184 | $65630 | $755486 | $(33247) |
| **Reconciliation of GAAP to adjusted net income (loss):** |  |  |  |  |
| GAAP net income (loss) | $124841 | $(121350) | $220431 | $(492905) |
| Plus: Share-based compensation expenses | 140786 | 114603 | 386790 | 334011 |
| Plus: Depreciation | 35730 | 70028 | 97198 | 117892 |
| Plus: Amortization of intangibles | 1554 | 1264 | 8504 | 3624 |
| Plus: Other |  |  | 893 |  |
| Plus: Impairment of equity investments | 18722 |  | 34216 |  |
| Plus: Discrete tax items | (926) | 962 | (9663) | 3365 |
| Plus: Income tax effect of non-GAAP adjustments<sup>1</sup> | (17044) | (13925) | (45747) | (37007) |
| Adjusted net income (loss) | $303663 | $51582 | $692622 | $(71020) |

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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| | | | | |
|:---|:---|:---|:---|:---|
| **Reconciliation of GAAP to adjusted EPS - basic** | | | | |
| GAAP earnings (loss) per share - basic | $0.09 | $(0.09) | $0.16 | $(0.36) |
| Plus: Share-based compensation expenses | 0.10 | 0.08 | 0.27 | 0.25 |
| Plus: Depreciation | 0.02 | 0.05 | 0.07 | 0.09 |
| Plus: Amortization of intangibles | 0.00 | 0.00 | 0.01 | 0.00 |
| Plus: Other | 0.00 | 0.00 | 0.00 | 0.00 |
| Plus: Impairment of equity investments | 0.01 | 0.00 | 0.02 | 0.00 |
| Plus: Discrete tax items | (0.00) | 0.00 | (0.01) | 0.00 |
| Plus: Income tax effect of non-GAAP adjustments<sup>1</sup> | (0.01) | (0.01) | (0.03) | (0.03) |
| Adjusted earnings (loss) per share - basic | $0.21 | $0.04 | $0.49 | $(0.05) |
| **Reconciliation of GAAP to adjusted EPS - diluted** |  |  |  |  |
| GAAP earnings (loss) per share - diluted | $0.08 | $(0.09) | $0.15 | $(0.36) |
| Plus: Share-based compensation expenses | 0.09 | 0.08 | 0.26 | 0.25 |
| Plus: Depreciation | 0.02 | 0.05 | 0.07 | 0.09 |
| Plus: Amortization of intangibles | 0.00 | 0.00 | 0.01 | 0.00 |
| Plus: Other | 0.00 | 0.00 | 0.00 | 0.00 |
| Plus: Impairment of equity investments | 0.01 | 0.00 | 0.02 | 0.00 |
| Plus: Discrete tax items | (0.00) | 0.00 | (0.01) | 0.00 |
| Plus: Income tax effect of non-GAAP adjustments<sup>1</sup> | (0.01) | (0.01) | (0.03) | (0.03) |
| Adjusted earnings (loss) per share - diluted | $0.20 | $0.04 | $0.47 | $(0.05) |
| **Reconciliation of GAAP to adjusted earnings (loss) per ADS - basic** |  |  |  |  |
| GAAP earnings (loss) per ADS - basic | $1.13 | $(1.15) | $2.03 | $(4.71) |
| Plus: Share-based compensation expenses | 1.28 | 1.08 | 3.56 | 3.19 |
| Plus: Depreciation | 0.32 | 0.66 | 0.90 | 1.13 |
| Plus: Amortization of intangibles | 0.01 | 0.01 | 0.08 | 0.03 |
| Plus: Other | 0.00 | 0.00 | 0.01 | 0.00 |
| Plus: Impairment of equity investments | 0.17 | 0.00 | 0.32 | 0.00 |
| Plus: Discrete tax items | (0.01) | 0.01 | (0.09) | 0.03 |
| Plus: Income tax effect of non-GAAP adjustments<sup>1</sup> | (0.15) | (0.13) | (0.42) | (0.35) |
| Adjusted earnings (loss) per ADS - basic | $2.76 | $0.49 | $6.38 | $(0.68) |
| **Reconciliation of GAAP to adjusted earnings (loss) per ADS - diluted** |  |  |  |  |
| GAAP earnings (loss) per ADS - diluted<sup>2</sup> | $1.09 | $(1.12) | $1.96 | $(4.71) |
| Plus: Share-based compensation expenses | 1.23 | 1.06 | 3.43 | 3.19 |
| Plus: Depreciation | 0.31 | 0.65 | 0.86 | 1.13 |
| Plus: Amortization of intangibles | 0.01 | 0.01 | 0.08 | 0.03 |
| Plus: Other | 0.00 | 0.00 | 0.01 | 0.00 |
| Plus: Impairment of equity investments | 0.16 | 0.00 | 0.30 | 0.00 |
| Plus: Discrete tax items | (0.01) | 0.01 | (0.09) | 0.03 |
| Plus: Income tax effect of non-GAAP adjustments<sup>1</sup> | (0.15) | (0.13) | (0.41) | (0.35) |
| Adjusted earnings (loss) per ADS - diluted | $2.65 | $0.48 | $6.14 | $(0.68) |

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**1. Tax effect of Non-GAAP adjustments is based on the statutory tax rate in the relevant tax jurisdiction. Please note that the Company currently records a valuation allowance on its net deferred tax assets, so there is no net impact recorded for deferred tax effects.**

**2. For the third quarter of 2024, GAAP diluted loss per ADS includes $0.03 loss per ADS attributable to the dilutive ADS outstanding for purposes of this reconciliation. As the Company was in a GAAP net loss position no diluted weighted average shares outstanding were calculated for US GAAP purposes.**

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| | |
|:---|:---|
| ![bgi2404beoneprimarylogorgb.jpg](bgi2404beoneprimarylogorgb.jpg) | **Exhibit 99.1** |

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| | | | | |
|:---|:---|:---|:---|:---|
| | **Three Months Ended<br>September 30,** | **Three Months Ended<br>September 30,** | **Nine Months Ended**<br>**September 30,** | **Nine Months Ended**<br>**September 30,** |
| | **2025** | **2024** | **2025** | **2024** |
| **Free Cash Flow (Non-GAAP):** |  |  |  |  |
| Net cash provided by (used in) operating activities (GAAP) | $402553 | $188369 | $710233 | $(215791) |
| Less: Purchases of property, plant and equipment | (48084) | (133655) | (148317) | (400183) |
| Free Cash Flow (Non-GAAP) | $354469 | $54714 | $561916 | $(615974) |

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