# EDGAR Filing Document

**Accession Number:** 0001435049
**File Stem:** 0001193125-23-051031
**Filing Date:** 2023-2
**Character Count:** 33161
**Document Hash:** 0c1b1e1480082460713acce3423a0dae
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-23-051031.hdr.sgml**: 20230227

**ACCESSION NUMBER**: 0001193125-23-051031

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 6

**FILED AS OF DATE**: 20230227

**DATE AS OF CHANGE**: 20230227

**EFFECTIVENESS DATE**: 20230227

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** CHINOOK THERAPEUTICS, INC.
- **CENTRAL INDEX KEY:** 0001435049
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-270072
- **FILM NUMBER:** 23676849

**BUSINESS ADDRESS:**
- **STREET 1:** 400 FAIRVIEW AVENUE NORTH, SUITE 900
- **CITY:** SEATTLE
- **STATE:** WA
- **ZIP:** 98109
- **BUSINESS PHONE:** 206-485-7051

**MAIL ADDRESS:**
- **STREET 1:** 400 FAIRVIEW AVENUE NORTH, SUITE 900
- **CITY:** SEATTLE
- **STATE:** WA
- **ZIP:** 98109

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ADURO BIOTECH, INC.
- **DATE OF NAME CHANGE:** 20111107

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ADURO BIOTECH
- **DATE OF NAME CHANGE:** 20080514

**As filed with the Securities and Exchange Commission on February 27, 2023** 

**Registration No. 333-** 

------

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**WASHINGTON, D.C. 20549** 

------

**FORM S-8** 

**REGISTRATION STATEMENT** 

***UNDER***

***THE SECURITIES ACT OF 1933***

------

## CHINOOK THERAPEUTICS, INC.
***(Exact name of Registrant as specified in its charter)***

------

---

| | |
|:---|:---|
| **Delaware** | **94-3348934** |
| ***(State or other jurisdiction of*** | ***(I.R.S. Employer*** |
| ***incorporation or organization)*** | ***Identification Number)*** |

---

**400 Fairview Avenue North, Suite 900** 

**Seattle, WA 98109** 

**(206) 485-7241** 

***(Address, including zip code, and telephone number, including area code, of Registrant's principal executive offices)***

**Chinook 2015 Equity Incentive Plan** 

**Chinook 2015 Employee Stock Purchase Plan** 

**Non-Plan Stock Option Agreement (Inducement Stock Option Award)** 

***(Full title of the plans)***

**Eric Dobmeier** 

**President and Chief Executive Officer** 

**Chinook Therapeutics, Inc.** 

**400 Fairview Avenue North, Suite 900** 

**Seattle, WA 98109** 

**(206) 485-7241** 

***(Name, address, including zip code, and telephone number, including area code, of agent for service)***

***Please send copies of all communications to:***

**Effie Toshav, Esq.** 

**Amanda L. Rose, Esq.** 

**Ryan Mitteness, Esq.** 

**Fenwick & West LLP 1191 2nd Ave.** 

**Seattle, Washington 98101** 

**(206) 389-4510** 

------

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definition of "large accelerated filer", "accelerated filer", "smaller reporting company", and "emerging growth company" in Rule 12b-2 of the Exchange Act.

---

| | | | |
|:---|:---|:---|:---|
| Large accelerated filer | ☒ | Accelerated filer | ☐ |
| Non-accelerated filer | ☐ | Smaller reporting company | ☒ |
|  |  | Emerging growth company | ☐ |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

------

**REGISTRATION OF ADDITIONAL SHARES** 

**PURSUANT TO GENERAL INSTRUCTION E** 

Pursuant to General Instruction E of Form S-8, Chinook Therapeutics, Inc. (the "***Registrant***") is filing this Registration Statement with the Securities and Exchange Commission (the "***Commission***") to register (a) 2,618,821 additional shares of common stock available for issuance under the Chinook 2015 Plan, pursuant to the provision of the Chinook 2015 Plan providing for an annual automatic increase in the number of shares reserved for issuance and (b) 654,705 additional shares of common stock available for issuance under the Chinook 2015 ESPP, pursuant to the provision of the Chinook 2015 ESPP providing for an annual 1% automatic increase in the number of shares reserved for issuance.

In accordance with General Instruction E of Form S-8, and only with respect to the common stock issuable under the Chinook 2015 Plan and Chinook 2015 ESPP, this Registration Statement hereby incorporates by reference the contents of the Registrant's Registration Statements on Form S-8 filed with the Commission on [April 20, 2015](http://www.sec.gov/Archives/edgar/data/1435049/000119312515136526/d912762ds8.htm) (File No. 333-203508), [March 8, 2016](http://www.sec.gov/Archives/edgar/data/1435049/000119312516496915/d151893ds8.htm) (File No. 333-210016), [March 1, 2017](http://www.sec.gov/Archives/edgar/data/1435049/000119312517065884/d338541ds8.htm) (File No. 333-216373), [March 1, 2018](http://www.sec.gov/Archives/edgar/data/1435049/000119312518067617/d469057ds8.htm) (File No. 333-223382), [February 27, 2019](http://www.sec.gov/Archives/edgar/data/1435049/000119312519054155/d712829ds8.htm) (File No. 333-229915), [March 9, 2020](http://www.sec.gov/Archives/edgar/data/1435049/000119312520067262/d895387ds8.htm) (File No. 333-237034), [April 7, 2021](http://www.sec.gov/Archives/edgar/data/0001435049/000156459021018047/kdny-s8.htm) (File No. 333-255109), [March 17, 2022](http://www.sec.gov/Archives/edgar/data/1435049/000119312522078400/d333263ds8.htm) (File No. 333-263649) and [November 10, 2022](http://www.sec.gov/Archives/edgar/data/1435049/000119312522282556/d361243ds8.htm) (File No. 333-268295), to the extent not superseded hereby.

**PART I** 

**INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS** 

The information called for by Part I of Form S-8 is omitted from this Registration Statement in accordance with Rule 428 of the Securities Act of 1933, as amended (the "Securities Act") and the instructions to Form S-8. In accordance with the rules and regulations of the Securities and Exchange Commission (the "Commission") and the instructions to Form S-8, such documents are not being filed with the Commission either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424. The documents containing the information specified in Part I of Form S-8 will be delivered to the participants in the equity benefit plans covered by this Registration Statement as specified by Rule 428(b)(1) under the Securities Act.

------

**PART II** 

**INFORMATION REQUIRED IN THE REGISTRATION STATEMENT** 

**Item 3. Incorporation of Documents by Reference.** 

The following documents filed by the Registrant with the Commission pursuant to the Securities Act and the Securities Exchange Act of 1934, as amended (the "Exchange Act") are incorporated herein by reference:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) The Registrant's Annual Report on Form 10-K for the year ended December 31, 2022, which includes
audited financial statements for the Registrant's latest fiscal year, filed with the Commission on February 27, 2023.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) all other reports filed pursuant to Section 13(a) or 15(d) of the Exchange Act since the end of the fiscal
year covered by the Registrant's Annual Report on [Form 10-K](http://www.sec.gov/Archives/edgar/data/../../../ix?doc=/Archives/edgar/data/1435049/000156459023002589/kdny-10k_20221231.htm) referred to in (a) above.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) The description of the Registrant's common stock which is contained in a registration statement on [Form 8-A](http://www.sec.gov/Archives/edgar/data/0001435049/000119312515126152/d906544d8a12b.htm) filed on April 10, 2015 (File No. 001-37345) under the Securities Exchange Act of 1934, as amended, or the Exchange Act, including any amendment or
report filed for the purpose of updating such description.

All documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent to the filing of this Registration Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing such documents, except as to specific sections of such documents as set forth therein. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document which also is deemed to be incorporated by reference herein modifies or supersedes such statement.

**Item 4. Description of Securities.** 

Not applicable.

**Item 5. Interests of Named Experts and Counsel.** 

Not applicable.

**Item 6. Indemnification of Directors and Officers.** 

The Registrant is incorporated under the laws of the State of Delaware. Section 145 of the Delaware General Corporation Law authorizes a court to award, or a corporation's board of directors to grant, indemnity to directors and officers under certain circumstances and subject to certain limitations. The terms of Section 145 of the Delaware General Corporation Law are sufficiently broad to permit indemnification under certain circumstances for liabilities, including reimbursement of expenses incurred, arising under the Securities Act.

The Registrant's amended and restated certificate of incorporation, as amended, and amended and restated bylaws, as amended, provide that the Registrant will indemnify its directors and officers, and may indemnify its employees and other agents, to the fullest extent permitted by the Delaware General Corporation Law. However, Delaware law prohibits the Registrant's certificate of incorporation from limiting the liability of the Registrant's directors for the following:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• any breach of the director's duty of loyalty to us or to our stockholders;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• acts or omissions not in good faith or that involve intentional misconduct or a knowing violation of law;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• unlawful payment of dividends or unlawful stock repurchases or redemptions; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• any transaction from which the director derived an improper personal benefit.

In addition, the Registrant has entered into, and intends to continue to enter, into indemnification agreements with each of its current directors and executive officers. These agreements will provide for the indemnification of directors and executive officers for all reasonable expenses and liabilities incurred in connection with any action or proceeding brought against them by reason of the fact that they are or were agents of the Registrant.

------

The Registrant currently carries liability insurance for its directors and executive officers for securities matters.

The indemnification provisions in the Registrant's restated certificate of incorporation and restated bylaws and the indemnification agreements to be entered into between the Registrant and each of its directors and executive officers is sufficiently broad to permit indemnification of the Registrant's directors and executive officers for liabilities arising under the Securities Act.

See also the undertakings set out in response to Item 9 hereof.

**Item 7. Exemption From Registration Claimed.** 

Not applicable.

**Item 8. Exhibits.** 

The following exhibits are filed herewith:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Exhibit** | | **Incorporated by Reference** | **Incorporated by Reference** | **Incorporated by Reference** | **Incorporated by Reference** | |
| **Number** | <br>**Exhibit Description** | **Form** | **File No.** | **Exhibit** | **Filing Date** | **Filed**<br>**Herewith** |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.1 | [Restated Certificate of Incorporation of the Registrant](http://www.sec.gov/Archives/edgar/data/1435049/000119312515138401/d910999dex31.htm) | 8-K | 001-37345 | 3.1 | 4/10/2015 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.2 | [Amendment to Amended and Restated Certificate of Incorporation](http://www.sec.gov/Archives/edgar/data/1435049/000119312520261293/d153950dex31.htm) | 8-K | 001-37345 | 3.1 | 10/5/2020 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.3 | [Certificate of Amendment to Amended and Restated Certificate of Incorporation of the Registrant](http://www.sec.gov/Archives/edgar/data/1435049/000119312520264856/d31443dex46.htm) | S-8 | 333-249351 | 4.6 | 10/6/2020 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.4 | [Amended and Restated Bylaws of the Registrant.](http://www.sec.gov/Archives/edgar/data/1435049/000119312523049013/d463440dex31.htm) | 8-K | 001-37345 | 3.1 | 02/24/2023 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.7 | [Form of Registrant's Common Stock certificate](http://www.sec.gov/Archives/edgar/data/1435049/000119312515119482/d804420dex41.htm) | S-1/A | 333-202667 | 4.1 | 04/06/2015 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5.1 | [Opinion of Fenwick & West LLP](d470696dex51.htm) |  |  |  |  | X |
| &nbsp;&nbsp;&nbsp;&nbsp;23.1 | [Consent of Fenwick & West LLP (contained in Exhibit 5.1)](d470696dex51.htm) |  |  |  |  | X |
| &nbsp;&nbsp;&nbsp;&nbsp;23.2 | [Consent of Independent Registered Public Accounting Firm](d470696dex232.htm) |  |  |  |  | X |
| &nbsp;&nbsp;&nbsp;&nbsp;24.1 | [Power of Attorney (included on the signature page to this Registration Statement)](d470696ds8.htm#sig) |  |  |  |  | X |
| &nbsp;&nbsp;&nbsp;&nbsp;99.1 | [Chinook 2015 Stock Equity Plan and forms of award agreements thereunder](http://www.sec.gov/Archives/edgar/data/1435049/000119312515119482/d804420dex108.htm) | S-1/A | 333-202667 | 10.8 | 4/6/2015 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;99.2 | [Chinook 2015 Employee Stock Purchase Plan](http://www.sec.gov/Archives/edgar/data/1435049/000119312515119482/d804420dex109.htm) | S-1/A | 333-202667 | 10.9 | 4/6/2015 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;99.3 | [Form of Inducement Stock Option Agreement](http://www.sec.gov/Archives/edgar/data/1435049/000156459021018017/kdny-ex1023_981.htm) | 10-K | 001-37345 | 10.23 | 4/7/2021 |  |
| 107 | [Filing Fees Exhibit](d470696dexfilingfees.htm) |  |  |  |  | X |

---

**Item 9. Undertakings.** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A. The undersigned Registrant hereby undertakes:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;

------

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii) To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in the volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20 percent change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective Registration Statement;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii) To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement;

<u>provided</u>, <u>however</u>, that paragraphs (a)(1)(i) and (a)(1)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial *bona fide* offering thereof.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.

B. The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial *bona fide* offering thereof.

C. Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered hereby, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

------

**SIGNATURES** 

Pursuant to the requirements of the Securities Act, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Seattle, State of Washington, on this 27th day of February, 2023.

---

| | |
|:---|:---|
| **CHINOOK THERAPEUTICS, INC.** | **CHINOOK THERAPEUTICS, INC.** |
| By: | /s/ Eric Dobmeier<u> </u> |
|  | Eric Dobmeier |
|  | President and Chief Executive Officer |

---

**POWER OF ATTORNEY** 

**KNOW ALL PERSONS BY THESE PRESENTS**, that each person whose signature appears below hereby constitutes and appoints Eric Dobmeier and Kirk Schumacher, and each of them, as his or her true and lawful attorney-in-fact and agent with full power of substitution, for him or her in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement on Form S-8, and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully for all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent, or his or her substitute, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities and on the date indicated.

---

| | | |
|:---|:---|:---|
| **Name** | **Title** | **Date** |
| /s/ Eric Dobmeier<br> Eric Dobmeier | Chief Executive Officer and Director<br> (Principal Executive Officer) | February 27, 2023 |
| /s/Eric Bjerkholt<br> Eric Bjerkholt | Chief Financial Officer<br> (Principal Financial and Accounting Officer) | February 27, 2023 |
| /s/ Srinivas Akkaraju<br> Srinivas Akkaraju | Director | February 27, 2023 |
| /s/ Jerel Davis<br> Jerel Davis | Director | February 27, 2023 |
| /s/ William M. Greenman<br> William M. Greenman | Director | February 27, 2023 |
| /s/ Michelle Griffin<br> Michelle Griffin | Director | February 27, 2023 |
| /s/ Ross Haghighat<br> Ross Haghighat | Director | February 27, 2023 |
| /s/ Mahesh Krishnan<br> Mahesh Krishnan | Director | February 27, 2023 |
| /s/ Dolca Thomas<br> Dolca Thomas | Director | February 27, 2023 |

---

## Exhibit 5.1

**Exhibit 5.1**![LOGO](g470696g0224092411735.jpg)

February 27, 2023

Chinook Therapeutics, Inc.

400 Fairview Avenue North, Suite 900

Seattle, WA 98109

Re: Registration Statement on Form S-8

Ladies and Gentlemen:

As counsel to Chinook Therapeutics, Inc., a Delaware corporation (the "***Company***"), we have examined the Registration Statement on Form S-8 (the "***Registration Statement***") to be filed by the Company with the Securities and Exchange Commission (the "***Commission***") on or about February 27, 2023 in connection with the registration under the Securities Act of 1933, as amended (the "***Securities Act***"), of an aggregate of 3,372,126 shares (the "***Plan Shares***") of the Company's Common Stock, $0.0001 par value per share (the "***Common Stock***"), that consists of (a) 2,618,821 shares of Common Stock that are subject to issuance by the Company upon the exercise or settlement of awards to be granted under the Chinook 2015 Equity Incentive Plan, as amended (the "***2015 Plan***"), (b) 654,705 shares of Common Stock subject to purchase rights to acquire such shares under the Company's 2015 Employee Stock Purchase Plan (the "***Purchase Plan***", and together with the 2015 Plan, the "***Plans***") and (c) 98,600 shares of Common Stock granted pursuant to inducement stock option awards (the "***Inducement Options***").

As to matters of fact relevant to the opinions rendered herein, we have examined such documents, certificates and other instruments which we have deemed necessary or advisable, including a certificate addressed to us and dated the date hereof executed by the Company (the "***Opinion Certificate***"). We have not undertaken any independent investigation to verify the accuracy of any such information, representations or warranties or to determine the existence or absence of any fact, and no inference as to our knowledge of the existence or absence of any fact should be drawn from our representation of the Company or the rendering of the opinion set forth below. We have not considered parol evidence in connection with any of the agreements or instruments reviewed by us in connection with this letter.

In our examination of documents for purposes of this letter, we have assumed, and express no opinion as to, the genuineness and authenticity of all signatures on original documents, the authenticity and completeness of all documents submitted to us as originals, that each document is what it purports to be, the conformity to originals of all documents submitted to us as copies or facsimile copies, the absence of any termination, modification or waiver of or amendment to any document reviewed by us (other than as has been disclosed to us), the legal competence or capacity of all persons or entities (other than the Company) executing the same and (other than the Company) the due authorization, execution, and delivery of all documents by each party thereto. We have also assumed the conformity of the documents filed with the Commission via the Electronic Data Gathering, Analysis and Retrieval System ("***EDGAR***"), except for required EDGAR formatting changes, to physical copies submitted for our examination.

The opinions in this letter are limited to the existing General Corporation Law of the State of Delaware now in effect. We express no opinion with respect to any other laws.

------

Based upon, and subject to, the foregoing, it is our opinion that the Shares, when issued and sold by the Company in accordance with the terms (including, without limitation, payment and authorization provisions) of the applicable Plans and the applicable form of award agreement thereunder or of the Inducement Awards, against the Company's receipt of payment therefor (in an amount and type of consideration not less than the par value per Share), and duly registered on the books of the transfer agent and registrar for the Shares in the name or on behalf of the holders thereof, will be validly issued, fully paid and non-assessable.

We consent to the use of this opinion as an exhibit to the Registration Statement and further consent to all references to us, if any, in the Registration Statement, the prospectuses constituting a part thereof and any amendments thereto. We do not thereby admit that we are within the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of the Commission thereunder.

This opinion is intended solely for your use in connection with the issuance and sale of the Shares subject to the Registration Statement and is not to be relied upon for any other purpose. In providing this letter, we are opining only as to the specific legal issues expressly set forth above, and no opinion shall be inferred as to any other matter or matters. This opinion is rendered on, and speaks only as of, the date of this letter first written above, and does not address any potential change in facts or law that may occur after the date of this opinion letter. We assume no obligation to advise you of any fact, circumstance, event or change in the law or the facts that may hereafter be brought to our attention, whether or not such occurrence would affect or modify any of the opinions expressed herein.

---

| |
|:---|
|  Very truly yours, |
|  /s/ Fenwick & West LLP |
| **FENWICK & WEST LLP** |

---

## Exhibit 23.2

**Exhibit 23.2**![LOGO](g470696pwc.jpg)

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of Chinook Therapeutics, Inc. of our report dated February 27, 2023 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in Chinook Therapeutics, Inc.'s Annual Report on Form 10-K for the year ended December 31, 2022.

/s/ PricewaterhouseCoopers LLP

San Francisco, California

February 27, 2023

## Ex-Filing

**Exhibit 107** 

**CALCULATION OF FILING FEE TABLES** 

**Form S-8** 

*(Form Type)* 

**Chinook Therapeutics, Inc.** 

*(Exact Name of Registrant as Specified in Its Charter)* 

**Table 1 – Newly Registered Securities** 

---

| | | | | |
|:---|:---|:---|:---|:---|
| &nbsp;&nbsp;&nbsp;Security Type | Security<br> Class Title | Fee<br>Calculation<br>Rule | Fee<br> Rate | Amount of<br>Registration<br> Fee |
| &nbsp;&nbsp;&nbsp;Equity | Common stock, par value<br>$0.0001 per share, 2015<br>Equity Incentive Plan | Rule 457(c)<br>and Rule<br>457(h)2618821<sup>(2)</sup>$22.80<sup>(3)</sup>$59696024.70<sup>(3)</sup> | 0.00011020 | $6578.50 |
| &nbsp;&nbsp;&nbsp;Equity | Common stock, par value<br>$0.0001 per share, 2015<br>Employee Stock Purchase<br>Plan | Rule 457(c)<br>and Rule<br>457(h)654705<sup>(4)</sup>$19.38<sup>(5)</sup>$12685400.40<sup>(5)</sup> | 0.00011020 | $1397.93 |
| &nbsp;&nbsp;&nbsp;Equity | — To be issued under an<br>Inducement Stock Option<br>Award, dated May 6, 2022 | Rule 457(h)45000<sup>(6)</sup>$13.64<sup>(7)</sup>$613800.00<sup>(7)</sup> | 0.00011020 | $67.64 |
| &nbsp;&nbsp;&nbsp;Equity | — To be issued under an<br>Inducement Stock Option<br>Award, dated July 29, 2022 | Rule 457(h)24700<sup>(8)</sup>$18.51<sup>(9)</sup>$457197.00<sup>(9)</sup> | 0.00011020 | $50.38 |
| &nbsp;&nbsp;&nbsp;Equity | — To be issued under an<br>Inducement Stock Option<br>Award, dated January 5,<br>2023 | Rule 457(h)28900<sup>(10)</sup>$24.50<sup>(11)</sup>$708050.00<sup>(11)</sup> | 0.00011020 | $78.03 |
| &nbsp;&nbsp;&nbsp;**Total Offering Amounts** | &nbsp;&nbsp;&nbsp;**Total Offering Amounts** | &nbsp;&nbsp;&nbsp;**Total Offering Amounts** |  | $74160472.10 |
| &nbsp;&nbsp;&nbsp;**Total Fee Offsets** | &nbsp;&nbsp;&nbsp;**Total Fee Offsets** | &nbsp;&nbsp;&nbsp;**Total Fee Offsets** |  |  |
| &nbsp;&nbsp;&nbsp;**Net Fee Due** | &nbsp;&nbsp;&nbsp;**Net Fee Due** | &nbsp;&nbsp;&nbsp;**Net Fee Due** |  | $8172.48 |

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(1) Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "  ***Securities Act*** "), this Registration Statement shall also cover any additional shares of the Registrant's common stock that become issuable in respect of the securities identified in the above table by reason of any stock dividend, stock
split, recapitalization or other similar transaction effected without receipt of consideration that increases the number of the Registrant's outstanding shares of common stock.

(2) Represents additional shares to be registered under the Chinook 2015 Equity Incentive Plan (the "Chinook
2015 Plan") resulting from the annual automatic increase in the number of authorized shares available for issuance under the Chinook 2015 Plan.

(3) Estimated solely for the purpose of calculating the registration fee in accordance with Rules 457(c) and
(h) under the Securities Act on the basis of the average of the high and low prices of the Registrant's common stock as reported on The Nasdaq Global Market on February 22, 2023.

(4) Represents additional shares to be registered under the Chinook 2015 Employee Stock Plan (the "Chinook
2015 ESPP") resulting from the annual automatic increase in the number of authorized shares available for issuance under the Chinook 2015 ESPP.

(5) Estimated in accordance with Rules 457(c) and 457(h) of the Securities Act solely for the purpose of
calculating the registration fee. The proposed maximum offering price per share of $19.38 was computed by averaging the high and low prices of a share of Registrant's common stock as reported on The Nasdaq Global Market on February 22,
2023, multiplied by 85%, which is the percentage of the trading price per share applicable to purchasers under the Chinook 2015 ESPP.

(6) Consists of 45,000 shares of the Registrant's common stock issuable under a new employment inducement
stock option award granted on May 6, 2022 in accordance with Nasdaq Listing Rule 5635(c)(4).

(7) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities
Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of $13.64 per share.

(8) Consists of 24,700 shares of the Registrant's common stock issuable under a new employment inducement
stock option award granted on July 29, 2022 in accordance with Nasdaq Listing Rule 5635(c)(4).

(9) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities
Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of $18.51 per share.

(10) Consists of 28,900 shares of the Registrant's common stock issuable under a new employment inducement
stock option award granted on January 5, 2023 in accordance with Nasdaq Listing Rule 5635(c)(4).

(11) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities
Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of $24.50 per share.