# EDGAR Filing Document

**Accession Number:** 0001383496
**File Stem:** 0000940400-26-011345
**Filing Date:** 2026-3
**Character Count:** 28478
**Document Hash:** 71939a69019165e06c595a6b0200a1b6
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000940400-26-011345.hdr.sgml**: 20260325

**ACCESSION NUMBER**: 0000940400-26-011345

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20260131

**FILED AS OF DATE**: 20260325

**DATE AS OF CHANGE**: 20260325

**PERIOD START**: 20260731

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** FIRST TRUST EXCHANGE-TRADED ALPHADEX FUND
- **CENTRAL INDEX KEY:** 0001383496

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** MA

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-22019
- **FILM NUMBER:** 26792045

**BUSINESS ADDRESS:**
- **STREET 1:** 120 EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187
- **BUSINESS PHONE:** 630-765-8000

**MAIL ADDRESS:**
- **STREET 1:** 120 EAST LIBERTY DRIVE, SUITE 400
- **CITY:** WHEATON
- **STATE:** IL
- **ZIP:** 60187

## Series and Classes Contracts Data

### First Trust Health Care AlphaDEX Fund (Series ID: S000017700)

| Class ID   | Class Name                            | Ticker Symbol   |
|:---|:---|:---|
| C000048900 | First Trust Health Care AlphaDEX Fund | FXH             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** First Trust Exchange-Traded AlphaDEX Fund

- **b. Investment Company Act file number:** 811-22019

- **c. CIK number of Registrant:** 0001383496

- **d. LEI of Registrant:** 549300PGRVU1P76W4537

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 120 East Liberty Drive

  - **City:** Wheaton

  - **State:** IL

  - **Foreign country:** US

  - **Zip / Postal Code:** 60187

  - **Telephone number:** 630-765-8000

**Item A.2. Information about the Series.**

- **a. Name of Series:** First Trust Health Care AlphaDEX Fund

- **b. EDGAR series identifier (if any):** S000017700

- **c. LEI of Series:** 5493009VIGFPXQC5HK94

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-07-31

- **b. Date as of which information is reported:** 2026-01-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $927954563.16

**Total Liabilities:** $752124.24

**Net Assets:** $927202438.92

**Cash Not Reported:** $1558.97

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000048900 | 6.01%                | -3.63%               | 0.64%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $1973873.89              | $51870106.63                               |
| Month 2  | $-121426.13              | $-35115908.90                              |
| Month 3  | $27050207.43             | $-22214324.84                              |

### Schedule of Portfolio Investments

| Name                               | Title                             | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Elanco Animal Health Inc           | Elanco Animal Health Inc          | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |    170550 | NS      | $4106844.00   | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                       | Illumina Inc                      | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |     29425 | NS      | $4261034.25   | 0.46%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc          | Halozyme Therapeutics Inc         | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |    183515 | NS      | $13159860.65  | 1.42%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMarin Pharmaceutical Inc        | BioMarin Pharmaceutical Inc       | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |    207817 | NS      | $11749973.18  | 1.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Penumbra Inc                       | Penumbra Inc                      | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |     52965 | NS      | $18970474.05  | 2.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Quest Diagnostics Inc              | Quest Diagnostics Inc             | CUSIP: 74834L100<br>LEI: 8MCWUBXQ0WE04KMXBX50 | Long             | EC               | CORP              | US        |     71174 | NS      | $13311673.22  | 1.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Labcorp Holdings Inc               | Labcorp Holdings Inc              | CUSIP: 504922105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49229 | NS      | $13366658.08  | 1.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corp                        | Incyte Corp                       | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |    208408 | NS      | $20855388.56  | 2.25%             |  |  |  | No            |                  1 | On Loan: No      |
| QIAGEN NV                          | QIAGEN NV                         | CUSIP: 000000000<br>LEI: 54930036WK3GMCN17Z57 | Long             | EC               | CORP              | NL        |    274182 | NS      | $14715347.94  | 1.59%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc         | Neurocrine Biosciences Inc        | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |     87079 | NS      | $11847968.74  | 1.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc                         | Natera Inc                        | CUSIP: 632307104<br>LEI: 529900CQ3OZ0A0VYVU59 | Long             | EC               | CORP              | US        |     89852 | NS      | $20768391.28  | 2.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                         | Insmed Inc                        | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    118274 | NS      | $18553642.38  | 2.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Perrigo Co PLC                     | Perrigo Co PLC                    | CUSIP: 000000000<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | IE        |   1183006 | NS      | $16810515.26  | 1.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Viking Therapeutics Inc            | Viking Therapeutics Inc           | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    109710 | NS      | $3185978.40   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc       | Thermo Fisher Scientific Inc      | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |      6661 | NS      | $3854121.21   | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Boston Scientific Corp             | Boston Scientific Corp            | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |     40478 | NS      | $3785907.34   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Medpace Holdings Inc               | Medpace Holdings Inc              | CUSIP: 58506Q109<br>LEI: 549300H8TYEUVTW14A54 | Long             | EC               | CORP              | US        |     36650 | NS      | $21347892.00  | 2.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Sotera Health Co                   | Sotera Health Co                  | CUSIP: 83601L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    933528 | NS      | $16915527.36  | 1.82%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc               | Align Technology Inc              | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |     52731 | NS      | $8596734.93   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals Inc          | Ionis Pharmaceuticals Inc         | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |    260200 | NS      | $21510734.00  | 2.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Cigna Group/The                    | Cigna Group/The                   | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |     59833 | NS      | $16400823.63  | 1.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Organon & Co                       | Organon & Co                      | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |   2870897 | NS      | $24517460.38  | 2.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Cardinal Health Inc                | Cardinal Health Inc               | CUSIP: 14149Y108<br>LEI: CCU46N3GJMF4OK4N7U60 | Long             | EC               | CORP              | US        |    100168 | NS      | $21524099.84  | 2.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                  | Veeva Systems Inc                 | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |     17289 | NS      | $3525572.88   | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Henry Schein Inc                   | Henry Schein Inc                  | CUSIP: 806407102<br>LEI: VGO3WGL8H45T73F4RR92 | Long             | EC               | CORP              | US        |    108942 | NS      | $8222942.16   | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Elevance Health Inc                | Elevance Health Inc               | CUSIP: 036752103<br>LEI: 8MYN82XMYQH89CTMTH67 | Long             | EC               | CORP              | US        |     46976 | NS      | $16241482.24  | 1.75%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEXX Laboratories Inc             | IDEXX Laboratories Inc            | CUSIP: 45168D104<br>LEI: OGMTXK0LUU1HKV2P0J84 | Long             | EC               | CORP              | US        |     24342 | NS      | $16320337.32  | 1.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Royalty Pharma PLC                 | Royalty Pharma PLC                | CUSIP: 000000000<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | US        |     99884 | NS      | $4163165.12   | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Humana Inc                         | Humana Inc                        | CUSIP: 444859102<br>LEI: 529900YLDW34GJAO4J06 | Long             | EC               | CORP              | US        |     32148 | NS      | $6275289.60   | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| Cooper Cos Inc/The                 | Cooper Cos Inc/The                | CUSIP: 216648501<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |     47090 | NS      | $3832184.20   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc                         | ResMed Inc                        | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |     34184 | NS      | $8830069.04   | 0.95%             |  |  |  | No            |                  1 | On Loan: No      |
| Encompass Health Corp              | Encompass Health Corp             | CUSIP: 29261A100<br>LEI: 549300FVRPM9DRQZRG64 | Long             | EC               | CORP              | US        |    116362 | NS      | $10999699.86  | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals Inc        | Apellis Pharmaceuticals Inc       | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |    655551 | NS      | $14802341.58  | 1.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Medtronic PLC                      | Medtronic PLC                     | CUSIP: 000000000<br>LEI: 549300GX3ZBSQWUXY261 | Long             | EC               | CORP              | IE        |     85715 | NS      | $8825216.40   | 0.95%             |  |  |  | No            |                  1 | On Loan: No      |
| Molina Healthcare Inc              | Molina Healthcare Inc             | CUSIP: 60855R100<br>LEI: 549300NQQCEQ46YHZ591 | Long             | EC               | CORP              | US        |    118615 | NS      | $21302067.85  | 2.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corp                        | Waters Corp                       | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |     21677 | NS      | $8036097.44   | 0.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Tempus AI Inc                      | Tempus AI Inc                     | CUSIP: 88023B103<br>LEI: 2549009LA0KWRAGQBX50 | Long             | EC               | CORP              | US        |     65362 | NS      | $3909954.84   | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc        | Inspire Medical Systems Inc       | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |     41848 | NS      | $3171241.44   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc             | UnitedHealth Group Inc            | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |     24942 | NS      | $7156608.06   | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| HCA Healthcare Inc                 | HCA Healthcare Inc                | CUSIP: 40412C101<br>LEI: 529900PH4ZGUH2MNEU89 | Long             | EC               | CORP              | US        |     44091 | NS      | $21528312.57  | 2.32%             |  |  |  | No            |                  1 | On Loan: No      |
| MSILF Treasury Portfolio           | MSILF Treasury Portfolio          | CUSIP: 61747C582<br>LEI: 549300D1XR6GP7EZ0T47 | Long             | STIV             | RF                | US        |    660398 | NS      | $660398.40    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Baxter International Inc           | Baxter International Inc          | CUSIP: 071813109<br>LEI: J5OIVXX3P24RJRW5CK77 | Long             | EC               | CORP              | US        |    201965 | NS      | $4053437.55   | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Inc         | Vertex Pharmaceuticals Inc        | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |     18162 | NS      | $8534323.80   | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc             | Intuitive Surgical Inc            | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |     21806 | NS      | $10995021.32  | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Chemed Corp                        | Chemed Corp                       | CUSIP: 16359R103<br>LEI: 54930020031IDJT2IM79 | Long             | EC               | CORP              | US        |     28867 | NS      | $12330250.38  | 1.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc                | Gilead Sciences Inc               | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |    100624 | NS      | $14283576.80  | 1.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc                         | Pfizer Inc                        | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |    826680 | NS      | $21857419.20  | 2.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Repligen Corp                      | Repligen Corp                     | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |    100498 | NS      | $15011386.26  | 1.62%             |  |  |  | No            |                  1 | On Loan: No      |
| Regeneron Pharmaceuticals Inc      | Regeneron Pharmaceuticals Inc     | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |     21334 | NS      | $15818094.30  | 1.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Revvity Inc                        | Revvity Inc                       | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |     85104 | NS      | $9259315.20   | 1.00%             |  |  |  | No            |                  1 | On Loan: No      |
| GE HealthCare Technologies Inc     | GE HealthCare Technologies Inc    | CUSIP: 36266G107<br>LEI: 549300OI9J7XOWZMUN85 | Long             | EC               | CORP              | US        |    100386 | NS      | $7927482.42   | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Exelixis Inc                       | Exelixis Inc                      | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |    281786 | NS      | $11654668.96  | 1.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc                          | Amgen Inc                         | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |     50310 | NS      | $17199982.80  | 1.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc        | Alnylam Pharmaceuticals Inc       | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |     31058 | NS      | $10499467.48  | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Zoetis Inc                         | Zoetis Inc                        | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |     65440 | NS      | $8168220.80   | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Abbott Laboratories                | Abbott Laboratories               | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |    131436 | NS      | $14365954.80  | 1.55%             |  |  |  | No            |                  1 | On Loan: No      |
| Universal Health Services Inc      | Universal Health Services Inc     | CUSIP: 913903100<br>LEI: 549300YGMGQDO0NMJD09 | Long             | EC               | CORP              | US        |     94414 | NS      | $19001761.64  | 2.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Acadia Healthcare Co Inc           | Acadia Healthcare Co Inc          | CUSIP: 00404A109<br>LEI: 5493005CW985Y9D0NC11 | Long             | EC               | CORP              | US        |   1450624 | NS      | $19496386.56  | 2.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Bristol-Myers Squibb Co            | Bristol-Myers Squibb Co           | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |    228971 | NS      | $12604853.55  | 1.36%             |  |  |  | No            |                  1 | On Loan: No      |
| STERIS PLC                         | STERIS PLC                        | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     15224 | NS      | $3997822.40   | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton Dickinson & Co              | Becton Dickinson & Co             | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |     42426 | NS      | $8632842.48   | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Zimmer Biomet Holdings Inc         | Zimmer Biomet Holdings Inc        | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |    183136 | NS      | $15945651.52  | 1.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Johnson & Johnson                  | Johnson & Johnson                 | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |     39785 | NS      | $9041141.25   | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                         | Biogen Inc                        | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |    116963 | NS      | $21040474.07  | 2.27%             |  |  |  | No            |                  1 | On Loan: No      |
| DAIWA CAPITAL MARKETS AMERICA INC. | DAIWA CAPITAL MARKETS AMERICA INC | CUSIP: 000000000<br>LEI: M67H5PRC0NQKM73ZAS82 | Long             | RA               | CORP              | US        |       291 | PA      | $291.00       | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| United Therapeutics Corp           | United Therapeutics Corp          | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |     33796 | NS      | $15866884.04  | 1.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                     | Eli Lilly & Co                    | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |     19154 | NS      | $19865571.10  | 2.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc           | Agilent Technologies Inc          | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |     28365 | NS      | $3796655.25   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Certara Inc                        | Certara Inc                       | CUSIP: 15687V109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    934590 | NS      | $8215046.10   | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc                         | AbbVie Inc                        | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |     36037 | NS      | $8036611.37   | 0.87%             |  |  |  | No            |                  1 | On Loan: No      |
| Tenet Healthcare Corp              | Tenet Healthcare Corp             | CUSIP: 88033G407<br>LEI: 0W9AIBT6U6ADJ2I8HK17 | Long             | EC               | CORP              | US        |     62150 | NS      | $11763752.00  | 1.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corp                       | Insulet Corp                      | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |     13578 | NS      | $3473388.18   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Edwards Lifesciences Corp          | Edwards Lifesciences Corp         | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |     45275 | NS      | $3683574.00   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services I     | West Pharmaceutical Services Inc  | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |     14026 | NS      | $3241689.12   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Merck & Co Inc                     | Merck & Co Inc                    | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |    156445 | NS      | $17251190.15  | 1.86%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics Inc           | Sarepta Therapeutics Inc          | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |    765216 | NS      | $15564493.44  | 1.68%             |  |  |  | No            |                  1 | On Loan: No      |
| Solventum Corp                     | Solventum Corp                    | CUSIP: 83444M101<br>LEI: 254900I70403OSGY4M28 | Long             | EC               | CORP              | US        |    259771 | NS      | $19994573.87  | 2.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Medical Inc                 | Globus Medical Inc                | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |    141457 | NS      | $12827320.76  | 1.38%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-03-25

**Name of Applicant:** First Trust Exchange-Traded AlphaDEX Fund

**Signature:** Derek Maltbie

**Name of Signer:** Derek Maltbie

**Title:** Treasurer, Chief Financial Officer and Chief Accounting Officer