# EDGAR Filing Document

**Accession Number:** 0001787306
**File Stem:** 0001787306-26-000028
**Filing Date:** 2026-4
**Character Count:** 265580
**Document Hash:** 1b528ccb143e471100c77028ff50636d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001787306-26-000028.hdr.sgml**: 20260421

**ACCESSION NUMBER**: 0001787306-26-000028

**CONFORMED SUBMISSION TYPE**: DEF 14A

**PUBLIC DOCUMENT COUNT**: 21

**CONFORMED PERIOD OF REPORT**: 20260421

**FILED AS OF DATE**: 20260421

**DATE AS OF CHANGE**: 20260421

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Arcutis Biotherapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001787306
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 812974255
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DEF 14A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-39186
- **FILM NUMBER:** 26880040

**BUSINESS ADDRESS:**
- **STREET 1:** 3027 TOWNSGATE ROAD
- **STREET 2:** SUITE 300
- **CITY:** WESTLAKE VILLAGE
- **STATE:** CA
- **ZIP:** 91361
- **BUSINESS PHONE:** 805-418-5006

**MAIL ADDRESS:**
- **STREET 1:** 3027 TOWNSGATE ROAD
- **STREET 2:** SUITE 300
- **CITY:** WESTLAKE VILLAGE
- **STATE:** CA
- **ZIP:** 91361

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Arcutis, Inc.
- **DATE OF NAME CHANGE:** 20190905

?xml version='1.0' encoding='ASCII'? arqt-20260421

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

 

**SCHEDULE 14A**

**Proxy Statement Pursuant to Section 14(a) of the**

**Securities Exchange Act of 1934**

 

Filed by the Registrant ⌧ Filed by a party other than the Registrant ☐

Check the appropriate box:

☐ Preliminary Proxy Statement

☐ **Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))**

⌧ Definitive Proxy Statement

☐ Definitive Additional Materials

☐ Soliciting Material Under §240.14a-12

**ARCUTIS BIOTHERAPEUTICS, INC.**

**(Name of Registrant as Specified in its Charter)**

**(Name of Person(s) Filing Proxy Statement, if other than the Registrant)**

Payment of Filing Fee (Check the appropriate box):

⌧ No fee required.

☐ Fee paid previously with preliminary materials.

☐ Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11.

a

**ARCUTIS BIOTHERAPEUTICS, INC.**

**3027 Townsgate Road, Suite 300**

**Westlake Village, CA 91361**

**NOTICE OF ANNUAL MEETING OF STOCKHOLDERS**

**TO BE HELD ON** June 5, 2026

To the Stockholders of Arcutis Biotherapeutics, Inc.:

**NOTICE IS HEREBY GIVEN** that the Annual Meeting of Stockholders (the "Annual Meeting") of Arcutis Biotherapeutics, Inc., a Delaware corporation (the "Company"), will be held virtually on June 5, 2026, at 7:30 a.m. PDT. Stockholders can attend the meeting via the internet at www.virtualshareholdermeeting.com/ARQT2026 by using the 16-digit control number that appears on the accompanying Proxy Card (printed in the box and marked by the arrow) and the instructions that accompanied these proxy materials.

The Annual Meeting will be held for the following purposes:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.To elect three Class III directors to hold office until the 2029 annual meeting of stockholders or until their successors are elected;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.To ratify the selection of Ernst & Young LLP as the independent registered public accounting firm of the Company for its fiscal year ending December 31, 2026;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4.To transact such other business as may properly come before the Annual Meeting or any adjournment or postponement thereof.

The foregoing items of business are more fully described in the Proxy Statement accompanying this Notice of Annual Meeting of Stockholders. Only stockholders who owned common stock of the Company at the close of business on April 8, 2026 (the "Record Date"), can vote at this meeting or any adjournments that take place.

The Board of Directors recommends that you vote:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **"FOR"** the election of the director nominees named in Proposal No. 1 of the Proxy Statement;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **"FOR"** the ratification of the selection of Ernst & Young LLP as the independent registered public accounting firm of the Company for its fiscal year ending December 31, 2026; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **"FOR"** the approval, on a non-binding advisory basis, of the compensation of the Company's named executive officers.

YOUR VOTE IS IMPORTANT. WHETHER OR NOT YOU PLAN TO ATTEND THE VIRTUAL ANNUAL MEETING, WE ENCOURAGE YOU TO READ THE ACCOMPANYING PROXY STATEMENT AND OUR ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2025, AND SUBMIT YOUR PROXY AS SOON AS POSSIBLE USING ONE OF THE THREE CONVENIENT VOTING METHODS DESCRIBED IN THE "INFORMATION ABOUT THE PROXY PROCESS AND VOTING" SECTION IN THE PROXY STATEMENT. IF YOU RECEIVE MORE THAN ONE SET OF PROXY MATERIALS OR NOTICE OF INTERNET AVAILABILITY BECAUSE YOUR SHARES ARE REGISTERED IN DIFFERENT NAMES OR ADDRESSES, EACH PROXY SHOULD BE SIGNED AND SUBMITTED TO ENSURE THAT ALL OF YOUR SHARES WILL BE VOTED.

---

| | |
|:---|:---|
| | By Order of the Board of Directors<br>/s/ Todd Franklin Watanabe |
| | Todd Franklin Watanabe |
| | *President, Chief Executive Officer and Director* |
| Westlake Village, California | |
| April 21, 2026 | |

---

------

**TABLE OF CONTENTS**

---

| | |
|:---|:---|
| <u>[PROXY STATEMENT](#i5b7359c782984761a76ae8f85e6ac771_10)</u> | <u>[4](#i5b7359c782984761a76ae8f85e6ac771_10)</u> |
| <u>[Information About the Proxy Process and Voting](#i5b7359c782984761a76ae8f85e6ac771_13)</u> | <u>[5](#i5b7359c782984761a76ae8f85e6ac771_13)</u> |
| <u>[PROPOSAL NO. 1 ELECTION OF DIRECTORS](#i5b7359c782984761a76ae8f85e6ac771_16)</u> | <u>[11](#i5b7359c782984761a76ae8f85e6ac771_16)</u> |
| <u>[Board Size and Structure](#i5b7359c782984761a76ae8f85e6ac771_19)</u>  | <u>[11](#i5b7359c782984761a76ae8f85e6ac771_19)</u> |
| <u>[Nominees for Election to a Three-Year Term Expiring at the 202](#i5b7359c782984761a76ae8f85e6ac771_22)[9](#i5b7359c782984761a76ae8f85e6ac771_22)[Annual Meeting of Stockholders](#i5b7359c782984761a76ae8f85e6ac771_22)</u> | <u>[12](#i5b7359c782984761a76ae8f85e6ac771_22)</u> |
| <u>[Directors Continuing in Office Until the 202](#i5b7359c782984761a76ae8f85e6ac771_25)[7](#i5b7359c782984761a76ae8f85e6ac771_25)[Annual Meeting of Stockholders](#i5b7359c782984761a76ae8f85e6ac771_25)</u>  | <u>[15](#i5b7359c782984761a76ae8f85e6ac771_25)</u> |
| <u>[Directors Continuing in Office Until the 202](#i5b7359c782984761a76ae8f85e6ac771_28)[8](#i5b7359c782984761a76ae8f85e6ac771_28)[Annual Meeting of Stockholders](#i5b7359c782984761a76ae8f85e6ac771_28)</u> | <u>[16](#i5b7359c782984761a76ae8f85e6ac771_28)</u> |
| <u>[Board Recommendation](#i5b7359c782984761a76ae8f85e6ac771_31)</u> | <u>[16](#i5b7359c782984761a76ae8f85e6ac771_31)</u> |
| <u>[PROPOSAL NO. 2 RATIFICATION OF SELECTION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM](#i5b7359c782984761a76ae8f85e6ac771_34)</u> | <u>[17](#i5b7359c782984761a76ae8f85e6ac771_34)</u> |
| <u>[Appointment of Independent Registered Public Accounting Firm](#i5b7359c782984761a76ae8f85e6ac771_37)</u> | <u>[17](#i5b7359c782984761a76ae8f85e6ac771_37)</u> |
| <u>[Principal Accountant Fees and Services](#i5b7359c782984761a76ae8f85e6ac771_40)</u> | <u>[17](#i5b7359c782984761a76ae8f85e6ac771_40)</u> |
| <u>[Pre-Approval Policies and Procedures](#i5b7359c782984761a76ae8f85e6ac771_43)</u> | <u>[17](#i5b7359c782984761a76ae8f85e6ac771_43)</u> |
| <u>[Board Recommendation](#i5b7359c782984761a76ae8f85e6ac771_46)</u>  | <u>[18](#i5b7359c782984761a76ae8f85e6ac771_46)</u> |
| <u>[Audit Committee Report](#i5b7359c782984761a76ae8f85e6ac771_49)</u> | <u>[19](#i5b7359c782984761a76ae8f85e6ac771_49)</u> |
| <u>[EXECUTIVE OFFICERS](#i5b7359c782984761a76ae8f85e6ac771_52)</u> | <u>[20](#i5b7359c782984761a76ae8f85e6ac771_52)</u> |
| <u>[CORPORATE GOVERNANCE](#i5b7359c782984761a76ae8f85e6ac771_55)</u> | <u>[22](#i5b7359c782984761a76ae8f85e6ac771_55)</u> |
| &nbsp;&nbsp;<u>[Code of Business Conduct and Ethics](#i5b7359c782984761a76ae8f85e6ac771_58)</u> | <u>[22](#i5b7359c782984761a76ae8f85e6ac771_58)</u> |
| &nbsp;&nbsp;<u>[Corporate Governance Guidelines](#i5b7359c782984761a76ae8f85e6ac771_61)</u> | <u>[22](#i5b7359c782984761a76ae8f85e6ac771_61)</u> |
| &nbsp;&nbsp;<u>[Leadership Structure of the Board](#i5b7359c782984761a76ae8f85e6ac771_64)</u> | <u>[22](#i5b7359c782984761a76ae8f85e6ac771_64)</u> |
| &nbsp;&nbsp;<u>[Independence of the Board of Directors](#i5b7359c782984761a76ae8f85e6ac771_67)</u> | <u>[22](#i5b7359c782984761a76ae8f85e6ac771_67)</u> |
| &nbsp;&nbsp;<u>[Board Skills Overview](#i5b7359c782984761a76ae8f85e6ac771_70)</u> | <u>[24](#i5b7359c782984761a76ae8f85e6ac771_70)</u> |
| &nbsp;&nbsp;<u>[Board Committees](#i5b7359c782984761a76ae8f85e6ac771_73)</u> | <u>[24](#i5b7359c782984761a76ae8f85e6ac771_73)</u> |
| &nbsp;&nbsp;<u>[Meetings of the Board of Directors, Board and Committee Member Attendance and Annual Meeting Attendance](#i5b7359c782984761a76ae8f85e6ac771_76)</u> | <u>[27](#i5b7359c782984761a76ae8f85e6ac771_76)</u> |
| &nbsp;&nbsp;<u>[Role of Board in Risk Oversight Process](#i5b7359c782984761a76ae8f85e6ac771_79)</u> | <u>[28](#i5b7359c782984761a76ae8f85e6ac771_79)</u> |
| &nbsp;&nbsp;<u>[Our Environmental, Social and Governance Principles](#i5b7359c782984761a76ae8f85e6ac771_82)</u> | <u>[28](#i5b7359c782984761a76ae8f85e6ac771_82)</u> |
| &nbsp;&nbsp;<u>[Compensation Committee Interlocks and Insider Participation](#i5b7359c782984761a76ae8f85e6ac771_85)</u> | <u>[30](#i5b7359c782984761a76ae8f85e6ac771_85)</u> |
| &nbsp;&nbsp;<u>[Pledging and Hedging Policy](#i5b7359c782984761a76ae8f85e6ac771_88)</u> | <u>[30](#i5b7359c782984761a76ae8f85e6ac771_88)</u> |
| &nbsp;&nbsp;<u>[Stockholder Communications with the Board of Directors](#i5b7359c782984761a76ae8f85e6ac771_91)</u> | <u>[30](#i5b7359c782984761a76ae8f85e6ac771_91)</u> |
| <u>[CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS](#i5b7359c782984761a76ae8f85e6ac771_94)</u> | <u>[31](#i5b7359c782984761a76ae8f85e6ac771_94)</u> |
| &nbsp;&nbsp;<u>[Director and Executive Officer Compensation](#i5b7359c782984761a76ae8f85e6ac771_97)</u> | <u>[31](#i5b7359c782984761a76ae8f85e6ac771_97)</u> |
| &nbsp;&nbsp;<u>[Employment Agreements](#i5b7359c782984761a76ae8f85e6ac771_100)</u> | <u>[31](#i5b7359c782984761a76ae8f85e6ac771_100)</u> |
| &nbsp;&nbsp;<u>[Indemnification Agreements and Directors' and Officers' Liability Insurance](#i5b7359c782984761a76ae8f85e6ac771_103)</u> | <u>[31](#i5b7359c782984761a76ae8f85e6ac771_103)</u> |
| &nbsp;&nbsp;<u>[Investor Rights Agreement](#i5b7359c782984761a76ae8f85e6ac771_106)</u> | <u>[31](#i5b7359c782984761a76ae8f85e6ac771_106)</u> |
| &nbsp;&nbsp;<u>[Policies and Procedures for Related Party Transactions](#i5b7359c782984761a76ae8f85e6ac771_112)</u> | <u>[32](#i5b7359c782984761a76ae8f85e6ac771_112)</u> |
| <u>[EXECUTIVE COMPENSATION](#i5b7359c782984761a76ae8f85e6ac771_115)</u> | <u>[32](#i5b7359c782984761a76ae8f85e6ac771_115)</u> |

---

------

---

| | |
|:---|:---|
| &nbsp;&nbsp;<u>[Compensation Discussion and Analysis](#i5b7359c782984761a76ae8f85e6ac771_118)</u> | <u>[32](#i5b7359c782984761a76ae8f85e6ac771_118)</u> |
| &nbsp;&nbsp;<u>[202](#i5b7359c782984761a76ae8f85e6ac771_127)[5](#i5b7359c782984761a76ae8f85e6ac771_127)[Summary Compensation Table](#i5b7359c782984761a76ae8f85e6ac771_127)</u> | <u>[61](#i5b7359c782984761a76ae8f85e6ac771_127)</u> |
| &nbsp;&nbsp;<u>[Grants of Plan Based Awards Tables](#i5b7359c782984761a76ae8f85e6ac771_130)</u> | <u>[62](#i5b7359c782984761a76ae8f85e6ac771_130)</u> |
| &nbsp;&nbsp;<u>[Outstanding Equity Awards at 202](#i5b7359c782984761a76ae8f85e6ac771_133)[5](#i5b7359c782984761a76ae8f85e6ac771_133)[Fiscal Year End](#i5b7359c782984761a76ae8f85e6ac771_133)</u> | <u>[63](#i5b7359c782984761a76ae8f85e6ac771_133)</u> |
| &nbsp;&nbsp;<u>[Equity Compensation Plan Information](#i5b7359c782984761a76ae8f85e6ac771_139)</u> | <u>[66](#i5b7359c782984761a76ae8f85e6ac771_139)</u> |
| <u>[DIRECTOR COMPENSATION](#i5b7359c782984761a76ae8f85e6ac771_142)</u> | <u>[68](#i5b7359c782984761a76ae8f85e6ac771_142)</u> |
| <u>[Non-Employee Director Compensation Program](#i5b7359c782984761a76ae8f85e6ac771_145)</u> | <u>[68](#i5b7359c782984761a76ae8f85e6ac771_145)</u> |
| <u>[INFORMATION ABOUT STOCK OWNERSHIP](#i5b7359c782984761a76ae8f85e6ac771_148)</u> | <u>[72](#i5b7359c782984761a76ae8f85e6ac771_148)</u> |
| <u>[Security Ownership of Certain Beneficial Owners and Management](#i5b7359c782984761a76ae8f85e6ac771_151)</u>  | <u>[72](#i5b7359c782984761a76ae8f85e6ac771_151)</u> |
| <u>[Delinquent Section 16(a) Reports](#i5b7359c782984761a76ae8f85e6ac771_154)</u>  | <u>[75](#i5b7359c782984761a76ae8f85e6ac771_154)</u> |
| <u>[PROPOSAL NO. 3 APPROVAL, ON A NON-BINDING ADVISORY BASIS, OF THE COMPENSATION OF OUR NAMED EXECUTIVE OFFICERS](#i5b7359c782984761a76ae8f85e6ac771_157)</u> | <u>[75](#i5b7359c782984761a76ae8f85e6ac771_157)</u> |
| <u>[Background](#i5b7359c782984761a76ae8f85e6ac771_160)</u> | <u>[75](#i5b7359c782984761a76ae8f85e6ac771_160)</u> |
| <u>[Board Recommendation](#i5b7359c782984761a76ae8f85e6ac771_163)</u>  | <u>[75](#i5b7359c782984761a76ae8f85e6ac771_163)</u> |
| <u>[ADDITIONAL INFORMATION](#i5b7359c782984761a76ae8f85e6ac771_166)</u> | <u>[76](#i5b7359c782984761a76ae8f85e6ac771_166)</u> |
| <u>[Householding of Proxy Materials](#i5b7359c782984761a76ae8f85e6ac771_169)</u> | <u>[76](#i5b7359c782984761a76ae8f85e6ac771_169)</u> |
| <u>[Other Matters](#i5b7359c782984761a76ae8f85e6ac771_172)</u> | <u>[76](#i5b7359c782984761a76ae8f85e6ac771_172)</u> |
| <u>[Copies of Notice and Proxy Card](#i5b7359c782984761a76ae8f85e6ac771_175)</u> | <u>[78](#i5b7359c782984761a76ae8f85e6ac771_175)</u> |

---

------

a

**ARCUTIS BIOTHERAPEUTICS, INC.**

**3027 Townsgate Road, Suite 300**

**Westlake Village, CA 91361**

**PROXY STATEMENT**

**FOR THE 2026 ANNUAL MEETING OF STOCKHOLDERS**

June 5, 2026

We have sent you this Proxy Statement and the enclosed Proxy Card because the Board of Directors (the "Board") of Arcutis Biotherapeutics, Inc. (referred to herein as the "Company", "Arcutis", "we", "us" or "our"), is soliciting your proxy to vote at our 2026 Annual Meeting of Stockholders (the "Annual Meeting") to be held on Friday, June 5, 2026, at 7:30 a.m. PDT, virtually at www.virtualshareholdermeeting.com/ARQT2026. There will be no physical meeting location. The meeting will only be conducted via an audio webcast.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• This Proxy Statement summarizes information about the proposals to be considered at the Annual Meeting and other information you may find useful in determining how to vote.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The Proxy Card is the means by which you actually authorize another person to vote your shares in accordance with your instructions.

In addition to solicitations by mail, our directors, officers and regular employees, without additional remuneration, may solicit proxies by telephone, e-mail and personal interviews. We may retain outside consultants to solicit proxies on our behalf as well. All costs of solicitation of proxies will be borne by us, Brokers, custodians and fiduciaries will be requested to forward proxy soliciting material to the owners of stock held in their names, and we will reimburse them for their reasonable out-of-pocket expenses incurred in connection with the distribution of proxy materials.

Pursuant to the rules adopted by the Securities and Exchange Commission (the "SEC"), we have elected to provide access to our Annual Meeting materials, which include this Proxy Statement and our Annual Report on Form 10-K for the year ended December 31, 2025 (the "Form 10-K"), over the internet in lieu of mailing printed copies. We will begin mailing the Notice of Internet Availability to our stockholders of record as of April 8, 2026 (the "Record Date"), for the first time on or about April 21, 2026. The Notice of Internet Availability will contain instructions on how to access and review the Annual Meeting materials, and will also contain instructions on how to request a printed copy of the Annual Meeting materials. In addition, we have provided brokers, dealers, banks, voting trustees and their nominees, at our expense, with additional copies of our proxy materials and the Form 10-K so that our record holders can supply these materials to the beneficial owners of shares of our common stock as of the Record Date. The Form 10-K is also available in the "Financials" section of our website at https://investors.arcutis.com/investor-relations.

The only outstanding voting securities of Arcutis are shares of common stock, $0.0001 par value per share (the "common stock"), of which there were 125,073,249 shares outstanding as of the Record Date (excluding any treasury shares). The holders of a majority of the voting power of the shares of stock entitled to vote at the Annual Meeting, present in person or represented by proxy, are required to hold the Annual Meeting.

------

**Information about the Proxy Process and Voting**

**Why am I receiving these materials?**

We have made this Proxy Statement and Proxy Card available to you on the internet or, upon your request, have delivered printed proxy materials to you, because the Board is soliciting your proxy to vote at the Annual Meeting, including at any adjournments or postponements of the Annual Meeting. You are invited to attend the Annual Meeting via internet to vote on the proposals described in this Proxy Statement. However, you do not need to attend the Annual Meeting to vote your shares. Instead, you may simply complete, sign and return the Proxy Card, or follow the instructions below to submit your proxy over the telephone or on the internet.

This Proxy Statement, the Notice of Internet Availability, the Notice of Annual Meeting and accompanying Proxy Card will be first made available for access by our stockholders on or about April 21, 2026, to all stockholders of record entitled to vote at the Annual Meeting.

**Who can vote at the Annual Meeting?**

Stockholders of record at the close of business on the Record Date will be entitled to notice of and to vote at the Annual Meeting. At the close of business on the Record Date, there were 125,073,249 shares of common stock issued and outstanding and entitled to vote. Each share of our common stock is entitled to one vote on any matter presented to stockholders at the Annual Meeting, with no cumulative voting rights. You will need to obtain your own internet access if you choose to attend the Annual Meeting online and/or vote over the internet.

***Stockholder of Record: Shares Registered in Your Name***

If, on the Record Date, your shares were registered directly in your name with the transfer agent for our common stock, Equiniti Trust Company, then you are a stockholder of record. As a stockholder of record, you may vote at the Annual Meeting or vote by proxy. Whether or not you plan to attend the Annual Meeting, we encourage you to fill out and return the Proxy Card or vote by proxy over the telephone or on the internet as instructed below (see "*How do I vote?*") to ensure your vote is counted.

***Beneficial Owner: Shares Registered in the Name of a Broker, Bank or Other Agent***

If, on the Record Date, your shares were held in an account at a brokerage firm, bank, dealer or other similar organization, then you are the beneficial owner of shares held in "street name" and these proxy materials are being forwarded to you by that organization. The organization holding your account is considered the stockholder of record for purposes of voting at the Annual Meeting. As a beneficial owner, you have the right to direct your broker or other agent on how to vote the shares in your account. You are also invited to attend the virtual Annual Meeting. However, since you are not the stockholder of record, you may not vote your shares at the virtual Annual Meeting unless you request and obtain a valid Proxy Card from your broker or other agent.

**What am I being asked to vote on?**

There are three matters scheduled for a vote:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Proposal No. 1 – the election of three Class III directors to hold office until our 2029 annual meeting of stockholders;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Proposal No. 2 – the ratification of the selection of Ernst & Young LLP as our independent registered public accounting firm for the year ending December 31, 2026; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Proposal No. 3 – the approval, on a non-binding advisory basis, of the compensation of our named executive officers.

------

In addition, you are entitled to vote on any other matters that are properly brought before the Annual Meeting. The Board knows of no other matters that will be presented for consideration at the Annual Meeting.

**What is the Board's voting recommendation?**

The Board recommends that you vote your shares:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• "FOR" the election of the director nominees;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• "FOR" the ratification of the selection of Ernst & Young LLP as the independent registered public accounting firm for the Company's fiscal year ending December 31, 2026; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• "FOR" the approval, on a non-binding advisory basis, of the compensation of the named executive officers.

**How do I vote?**

For Proposal No. 1, you may either vote "For" all the nominees to the Board or you may "Withhold" your vote for any nominee you specify. For Proposal Nos. 2 and 3, you may vote "For" or "Against" or abstain from voting.

Please note that by casting your vote by proxy you are authorizing the individuals listed on the Proxy Card to vote your shares in accordance with your instructions and in their discretion with respect to any other matter that properly comes before the Annual Meeting or any adjournments or postponements thereof.

The procedures for voting depend on whether your shares are registered in your name or are held by a bank, broker or other agent:

***Stockholder of Record: Shares Registered in Your Name***

If you are a stockholder of record, you may vote at the virtual Annual Meeting. Alternatively, you may vote by proxy, by using the accompanying Proxy Card, over the internet or by telephone. Whether or not you plan to attend the Annual Meeting, we encourage you to vote by proxy to ensure your vote is counted. Even if you have submitted a proxy before the Annual Meeting, you may still attend the virtual Annual Meeting and vote by following the instructions described below. In such case, your previously submitted proxy will be disregarded.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **<u>At the Annual Meeting</u>** – To vote by attending the virtual Annual Meeting, vote your shares at www.virtualshareholdermeeting.com/ARQT2026 during the Annual Meeting. You will need the 16-digit control number which appears on the accompanying Proxy Card (printed in the box and marked by the arrow) and the instructions that accompanied these proxy materials. For additional details on the virtual meeting, please see page 7 of this Proxy Statement.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **<u>By Mail</u>** – To vote using the Proxy Card, simply complete, sign and date the accompanying Proxy Card and return it promptly in the envelope provided. If you return your signed Proxy Card to us before the Annual Meeting, we will vote your shares in accordance with the Proxy Card.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **<u>Via the Internet</u>** – To vote by proxy over the internet, follow the instructions provided on the Notice of Internet Availability.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **<u>By Telephone</u>** – To vote by telephone, you may vote by proxy by calling the toll free number found on the Notice of Internet Availability.

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***Beneficial Owner: Shares Registered in the Name of Broker, Bank or Other Agent***

If you are a beneficial owner of shares registered in the name of your broker, bank or other agent, you will receive a voting instruction card and voting instructions with these proxy materials from that organization rather than from us. To vote at the virtual Annual Meeting, you must obtain a valid proxy from your broker, bank or other agent. Follow the instructions from your broker, bank or other agent included with these proxy materials, or contact your broker, bank or other agent to request a proxy form.

We provide internet proxy voting to allow you to vote your shares online, with procedures designed to ensure the authenticity and correctness of your proxy vote instructions. However, please be aware that you must bear any costs associated with your internet access, such as usage charges from internet access providers and telephone companies.

**Who counts the votes?**

Broadridge Financial Solutions, Inc. ("Broadridge"), has been engaged as our independent agent to tabulate stockholder votes and a representative of Broadridge will act as inspector of election ("Inspector of Election").

**What is the quorum requirement?**

A quorum of stockholders is necessary to hold a valid meeting. A quorum will be present if the holders of a majority of the voting power of the shares of stock entitled to vote at the Annual Meeting are present in person (or by remote communication, if applicable) or represented by proxy. Shares are considered present "in person" if voted by the holder of those shares during the Annual Meeting or by proxy. On the Record Date, there were 125,073,249 shares outstanding and entitled to vote. Accordingly, 62,536,625 shares must be represented by stockholders present at the Annual Meeting or by proxy to have a quorum.

If there is no quorum, either the Chair of the Annual Meeting or the holders of a majority of the shares entitled to vote who are present in person (or by remote communication, if applicable) or represented by proxy at the Annual Meeting may adjourn the Annual Meeting to another time or place.

**How many votes are needed to approve each proposal?**

Proposal No. 1 (the election of director nominees) requires the approval of a plurality of the votes cast. This means that the three nominees who receive the most affirmative "For" votes will be elected as directors to our Board. Votes withheld and broker non-votes are not considered votes cast and thus will have no effect on the outcome of this proposal.

Proposal No. 2 (the ratification of the selection of Ernst & Young LLP as the independent registered public accounting firm for the Company's fiscal year ending December 31, 2026) requires the majority of the votes cast. Abstentions and broker non-votes are not considered votes cast and thus will have no effect, however, Proposal No. 2 is considered to be a "routine" matter under applicable laws and thus we do not expect any broker non-votes.

Proposal No. 3 (the non-binding advisory vote to approve the compensation of the named executive officers) requires the majority of votes cast. Abstentions and broker non-votes are not considered votes cast and thus will have no effect. This vote is advisory and not binding on us, our Board, or our Compensation Committee.

**What is a vote withheld and an abstention and how will they be treated?**

A vote withheld (in the case of the proposal regarding the election of director nominees) or an abstention (in the case of the proposal regarding the ratification of the selection of Ernst & Young LLP as the independent registered public accounting firm for the Company's fiscal year ending December 31, 2026) represents a stockholder's affirmative choice to decline to vote on a proposal. As a result, votes withheld and abstentions are counted as present and entitled to vote for purposes of determining a quorum. Votes withheld have no effect on the election of director nominees. Abstentions have no effect

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on the ratification of the selection of Ernst & Young LLP as the independent registered public accounting firm.

**What are "broker non-votes"?**

A "broker non-vote" occurs when a beneficial owner of shares held in "street name" does not give instructions to the broker, bank or other agent holding the shares as to how to vote on "non-routine" proposals. Generally, if shares are held in street name, the beneficial owner of the shares is entitled to give voting instructions to the broker, bank or other agent holding the shares. If the beneficial owner does not provide voting instructions, the broker, bank or other agent can still vote the shares with respect to matters that are considered to be "routine" under the applicable rules but cannot vote with respect to "non-routine" matters. On non-routine matters, any "uninstructed shares" may not be voted by the broker, bank or other agent and are considered to be "broker non-votes."

Broker non-votes will be counted for the purpose of determining whether a quorum is present at the Annual Meeting.

If you own shares through a nominee, such as a broker, bank or other agent, please be sure to instruct your nominee how to vote to ensure that your vote is counted on each of the proposals.

**Which proposals are routine and which are non-routine?**

The following proposal is considered a routine matter:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Proposal No. 2 (the ratification of the selection of Ernst & Young LLP as the independent registered public accounting firm for the Company's fiscal year ending December 31, 2026).

A broker, bank or other agent generally has discretionary voting power with respect to such proposal and therefore no broker non-votes are expected to exist in connection with Proposal No. 2.

The following proposals are considered non-routine matters:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Proposal No. 1 (the election of director nominees); and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Proposal No. 3 (the non-binding advisory vote to approve the compensation of the named executive officers).

A broker, bank or other agent generally cannot vote with respect to such proposals without voting instructions from the respective beneficial owner and therefore there may be broker non-votes on such proposals. If you own shares through a nominee, such as a broker, bank or other agent, and do not instruct your nominee how to vote your shares for these proposals, the nominee will inform the Inspector of Election that it does not have the authority to vote on the matter with respect to your shares, which is referred to above as a "broker non-vote." Therefore, broker non-votes may exist in connection with Proposal No. 1 and Proposal No. 3.

**What if I return a Proxy Card but do not make specific choices?**

If we receive a signed and dated Proxy Card and the Proxy Card does not specify how your shares are to be voted, your shares will be voted in accordance with the recommendations of the Board. The Board's recommendations are set forth above, as well as with the description of each proposal in this Proxy Statement.

**Who is paying for this proxy solicitation?**

We have retained Morrow Sodali LLC, 333 Ludlow Street, Fifth Floor, South Tower, Stamford, CT 06902, to assist in the solicitation of proxies for a fee of approximately $10,000, plus distribution costs and other costs and expenses. We will pay for the entire cost of soliciting proxies. In addition to these mailed proxy materials, our directors, officers and employees may also solicit proxies in person, by telephone or

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by other means of communication. Directors, officers and employees will not be paid any additional compensation for soliciting proxies. We may also reimburse brokerage firms, banks and other agents for the cost of forwarding proxy materials to beneficial owners.

**What does it mean if I receive more than one set of materials?**

If you receive more than one set of materials, your shares are registered in more than one name or are registered in different accounts. In order to vote all the shares you own, you must either sign and return all of the Proxy Cards or follow the instructions for any alternative voting procedure on each of the Proxy Cards.

**Can I change my vote after submitting my proxy?**

Yes. You can revoke your proxy at any time before the final vote at the Annual Meeting. If you are the record holder of your shares, you may revoke your proxy in any one of the following ways on or before the close of voting for the Annual Meeting:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• You may submit another properly completed proxy with a later date.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• You may grant a subsequent timely proxy by telephone or through the internet.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• You may send a timely written notice that you are revoking your proxy to our Corporate Secretary at 3027 Townsgate Road, Suite 300, Westlake Village, CA 91361.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• You may attend the virtual Annual Meeting and vote at the meeting by following the instructions described above. Simply attending the Annual Meeting will not, by itself, revoke your proxy.

Your most current proxy card or telephone or internet proxy is the one that is counted, so long as it is provided within the applicable deadline. If your shares are held by your broker, banker or other agent, you should follow the instructions provided by your broker, bank or other agent to change your vote or revoke your proxy.

**How do I attend the virtual Annual Meeting?**

The live audio webcast of the Annual Meeting. Any stockholder can attend the Annual Meeting live online at www.virtualshareholdermeeting.com/ARQT2026. Online access to the audio webcast will open approximately 15 minutes prior to the start of the Annual Meeting to allow time for our stockholders to log in and test their devices' audio system. We encourage our stockholders to access the meeting in advance of the designated start time.

If you were a stockholder as of the Record Date, or you hold a valid proxy for the Annual Meeting, you can vote at the Annual Meeting. A summary of the information you need to attend the Annual Meeting online is provided below:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Instructions on how to attend and participate via the internet, including how to demonstrate proof of stock ownership, are posted at www.virtualshareholdermeeting.com/ARQT2026.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Assistance with questions regarding how to attend and participate via the internet will be provided at www.virtualshareholdermeeting.com/ARQT2026 on the day of the Annual Meeting.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Webcast starts at 7:30 a.m. PDT.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• You will need your 16-digit control number on the proxy card or voting instruction form.

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**Can I submit questions prior to or at the virtual Annual Meeting?**

Stockholders may submit questions and vote on the day of, or during, the Annual Meeting on www.virtualshareholdermeeting.com/ARQT2026. To demonstrate proof of stock ownership, you will need to enter the 16-digit control number received with your proxy card or voting instruction form to submit questions and vote at our Annual Meeting. We intend to answer questions submitted during the meeting that are pertinent to the Company and the items being brought before stockholder vote at the Annual Meeting, as time permits, and in accordance with the Rules of Conduct for the Annual Meeting. Questions and answers will be grouped by topic and substantially similar questions will be answered only once. To promote fairness, efficiently use the Company's resources and ensure all stockholder questions are able to be addressed, we will respond to no more than three questions from a single stockholder.

**Is technical assistance provided before and during the virtual Annual Meeting?**

If you encounter any difficulties accessing the virtual meeting during the check-in time or meeting time, or you have any questions regarding how to use the virtual meeting platform, please call the technical support number that will be posted on the virtual shareholder meeting log-in page.

**When are stockholder proposals due for next year's Annual Meeting?**

Stockholders who intend to have a proposal considered for inclusion in our proxy materials for presentation at our 2027 Annual Meeting of Stockholders pursuant to Rule 14a-8 under the Securities Exchange Act of 1934, as amended (the "Exchange Act") must submit the proposal to our Corporate Secretary at 3027 Townsgate Road, Suite 300, Westlake Village, CA 91361 no later than December 22, 2026.

Stockholders intending to present a proposal at the 2027 Annual Meeting of Stockholders, but not to include the proposal in our proxy statement, or to nominate a person for election as a director, must comply with the requirements in our bylaws. Our bylaws require, among other things, that our Corporate Secretary receive written notice from the stockholder of record of their intent to present such proposal or nomination not later than the close of business on the 75th day nor earlier than the close of business on the 105th day prior to June 5, 2027. Therefore, we must receive notice of such a proposal or nomination for the 2027 Annual Meeting of Stockholders no earlier than the close of business on February 20, 2027 and no later than the close of business on March 22, 2027. The notice must contain the information required by the bylaws, a copy of which is available upon request to our Corporate Secretary. In the event that the date of the 2027 Annual Meeting of Stockholders is more than 30 days before or more than 60 days after June 5, 2027, then our Corporate Secretary must receive such written notice not earlier than the close of business on the 105th day prior to the 2027 Annual Meeting and not later than the close of business on the 75th day prior to the 2027 Annual Meeting or, if later, the close of business on the 10th day following the day on which public disclosure of the date of such annual meeting is first made by us. You are advised to review our bylaws, which contain additional requirements about advance notice of stockholder proposals and director nominations. In addition to satisfying the foregoing requirements under the Company's bylaws, to comply with the universal proxy rules, any notice of director nomination submitted to the Company must include the additional information required by Rule 14a-19 under the Exchange Act no later than April 6, 2027.

We intend to file our Proxy Statement and WHITE proxy card with the SEC in connection with our solicitation of proxy for our 2026 Annual Stockholders Meeting. Stockholders may obtain our Proxy Statement (and any amendments or supplements thereto) and other documents as and when filed by the Company with the SEC without charge from the Company's website at www.sec.gov.

**How can I find out the results of the voting at the Annual Meeting?**

Voting results will be announced by the filing of a Current Report on Form 8-K within four business days after the Annual Meeting. If final voting results are unavailable at that time, we will file an amended Current Report on Form 8-K within four business days of the day the final results are available.

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**a**

**PROPOSAL NO. 1**

**ELECTION OF DIRECTORS**

**Board Size and Structure**

The Board currently consists of nine seated directors, divided into the three following classes:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• *Class III directors*: Patrick J. Heron, Neha Krishnamohan, and Todd Franklin Watanabe, whose current terms will expire at the Annual Meeting;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• *Class I directors*: Terrie Curran, Halley Gilbert and Keith Leonard, Jr., whose current terms will expire at the annual meeting of stockholders to be held in 2027; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• *Class II directors*: Sue-Jean Lin, Amit D. Munshi and Howard G. Welgus, M.D., whose current terms will expire at the annual meeting of stockholders to be held in 2028.

At each annual meeting of stockholders, the successors to directors whose terms will then expire will be elected to serve from the time of election and qualification until the third subsequent annual meeting of stockholders and until each such director's successor is duly elected and qualified, or until such director's earlier death, resignation, disqualification or removal.

Mr. Heron, Ms. Krishnamohan and Mr. Watanabe have been nominated to serve as Class III directors and have each elected to stand for re-election. Each director to be elected will hold office from the date of their election by the stockholders until the third subsequent annual meeting of stockholders and until his or her successor is elected and has been qualified, or until such director's earlier death, resignation, disqualification or removal.

Shares represented by executed proxies will be voted, if authority to do so is not withheld, for the election of these three nominees. In the event that any nominee should be unavailable for election as a result of an unexpected occurrence, such shares will be voted for the election of such substitute nominee as the Board may propose. Each person nominated for election has agreed to serve if elected, and management has no reason to believe that any nominee will be unable to serve. Directors are elected by a plurality of the votes cast at the meeting.

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The following table sets forth, for the Class III nominees (who are currently standing for re-election) and for our other current directors who will continue in office after the Annual Meeting, information with respect to their ages as of April 8, 2026, tenure on the Board, and position/office held within the Company:

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| | | | |
|:---|:---|:---|:---|
| **Name** | **Age** | **Position/Office Held With the Company** | **Director Since** |
| *Class III Directors whose terms expire at the Annual Meeting of Stockholders* | *Class III Directors whose terms expire at the Annual Meeting of Stockholders* | *Class III Directors whose terms expire at the Annual Meeting of Stockholders* |  |
| Patrick J. Heron (2) | 55 | Director | 2016 |
| Neha Krishnamohan (1) | 39 | Director | 2022 |
| Todd Franklin Watanabe | 58 | President, Chief Executive Officer and Director | 2017 |
| *Class I Directors whose terms expire at the 2027 Annual Meeting of Stockholders* | *Class I Directors whose terms expire at the 2027 Annual Meeting of Stockholders* | *Class I Directors whose terms expire at the 2027 Annual Meeting of Stockholders* |  |
| Terrie Curran (3) | 57 | Director | 2020 |
| Halley E. Gilbert (1) | 56 | Director | 2020 |
| Keith R. Leonard, Jr. (2) | 64 | Chairperson and Director | 2021 |
| *Class II Directors whose terms expire at the 2028 Annual Meeting of Stockholders* | *Class II Directors whose terms expire at the 2028 Annual Meeting of Stockholders* | *Class II Directors whose terms expire at the 2028 Annual Meeting of Stockholders* |  |
| Sue-Jean Lin (1) (3) | 67 | Director | 2021 |
| Amit D. Munshi (2) | 58 | Director | 2025 |
| Howard G. Welgus, M.D. (3) | 74 | Director | 2020 |

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(1)Member of the Audit Committee.

(2)Member of the Compensation Committee.

(3)Member of the Nominating and Corporate Governance Committee.

**Nominees for Election to a Three-Year Term Expiring at the 2029 Annual Meeting of Stockholders**

***Patrick J. Heron*** has been a member of our Board of Directors since April 2016. Since September 1999, Mr. Heron has been a managing general partner with Frazier Life Sciences, where he has been active in company formations and initial investments in various biotechnology companies, including Marcadia Biotech Inc., Calixa Therapeutics, Inc. and VentiRx Pharmaceuticals, Inc. He also led Frazier's involvement in MedPointe Inc. Prior to joining Frazier, Mr. Heron helped develop McKinsey & Company's west coast biotechnology consulting practice. In addition, Mr. Heron currently serves on the Board of Directors of the following public companies: MBX Biosciences, Inc. and Mirum Pharmaceuticals, Inc. He also previously served on the Board of Directors of other public companies including Vaxcyte, Inc. (2017 to 2021), Passage Bio, Inc. (2018 to 2021) and Imago Biosciences, Inc. (2014 to 2022). In addition, Mr. Heron currently serves on the Board of Directors of several private companies: Alpha-9 Theranostics, Inc., Alceptor Therapeutics, Inc., Bluewater Biosciences, Inc. and Tubulis GmbH. Mr. Heron received a B.A. in Political Science from the University of North Carolina at Chapel Hill and an M.B.A. from Harvard Business School. We believe that Mr. Heron is qualified to serve on our Board of Directors because of his investing and operations experience in the life sciences industry.

***Neha Krishnamohan*** has served as a member of our Board of Directors since September 2022. Ms. Krishnamohan is currently the Chief Financial Officer and Chief Business Officer at Latigo Biotherapeutics, a clinical-stage biotechnology company developing best-in-class non-opioid pain treatments that target pain at its source. Previously, Ms. Krishnamohan was the Chief Financial Officer and Executive Vice President, Corporate Development at Artiva Biotherapeutics, Inc., an off-the-shell NK cell therapy company focused on autoimmune and oncology indications from April 2024 to December 2025. Ms. Krishnamohan served as Chief Financial Officer and Executive Vice President, Corporate Development at Kinnate Biopharma Inc., a publicly traded biopharmaceutical company from June 2021 until its acquisition by XOMA Corporation in April 2024. Prior to joining Kinnate, Ms. Krishnamohan was with Goldman Sachs where she held various roles since July 2008, most recently as Vice President in the Healthcare Investment Banking Group. During Ms. Krishnamohan's tenure at Goldman Sachs, she

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advised a variety of biopharmaceutical company Board of Directors and management teams on a broad range of strategic financial matters, and executing financings and leading M&A transactions. Ms. Krishnamohan holds a B.S.E. with a double major in Biomedical Engineering and Economics from Duke University. We believe that Ms. Krishnamohan is qualified to serve on our Board of Directors because of her business and financial expertise, including capital markets, and her experience as a senior executive in the biopharmaceutical industry.

***Todd Franklin Watanabe*** has served as our President and Chief Executive Officer, and as a member of our Board of Directors, since April 2017. Prior to joining Arcutis, he served as co-founder and Chief Operating Officer of Kanan Therapeutics, Inc., a cardiovascular drug development company from December 2015 to February 2018, and before that, he served as Vice President of Strategy and Corporate Development at Kythera Biopharmaceuticals Inc. from October 2013 to November 2015. Mr. Watanabe was an executive at Amgen Inc. from 2005 to 2013, where he was involved in the development of Repatha for hyperlipidemia and Aimovig for migraine, and worked on the U.S. marketing of Enbrel in both dermatology and rheumatology. Previously, he was an executive with Eli Lilly and Company, and an official in the U.S. Government. He was also a commissioned officer in the U.S. Navy Reserves for 25 years. Mr. Watanabe is also the Vice Chairperson of the Biotechnology Innovation Organization (BIO), and co-chairs that board's advocacy and nominations, governance & membership committees. Mr. Watanabe received his M.A. in National Security Studies, and his B.A. in International Relations, both from Georgetown University. We believe that Mr. Watanabe is qualified to serve on our Board of Directors because of his expertise in dermatology and experience with biotechnology companies, including working with and serving in various executive positions in life sciences companies.

**Directors Continuing in Office Until the 2027 Annual Meeting of Stockholders**

***Terrie Curran*** has served as a member of our Board of Directors since November 2020 and has served as the Chair of the Nominating and Corporate Governance Committee since 2021. Ms. Curran served as the Chief Executive Officer and President of Phathom Pharmaceuticals, Inc., a late clinical-stage biopharmaceutical company focused on developing and commercializing new treatments for gastrointestinal diseases, from December 2019 to March 2025, and served as a member of its Board of Directors since August 2019 to March 2025. From November 2016 to 2023, Ms. Curran served as a member of the Board of Directors of Myovant Sciences Ltd., a clinical-stage biopharmaceutical company with a focus on treatments for women suffering from uterine fibroids, endometriosis and infertility and men suffering from prostate cancer. Ms. Curran previously served as the President, Global Inflammation and Immunology (I&I) Franchise at Celgene Corporation and a member of its Executive Committee from April 2017 until November 2019. Ms. Curran joined Celgene in 2013 as the U.S. Commercial Head of the I&I Franchise and built the capabilities and recruited the teams that executed the successful launch of OTEZLA, before becoming Head of Worldwide Markets. Prior to joining Celgene, she served as Senior Vice President and General Manager - Global Women's Health at Merck & Co. Before joining Merck, Ms. Curran held a number of Country General Manager positions at Schering-Plough and Pharmacia across Europe and Asia Pacific. She previously served on the board of H. Lundbeck A/S, a global pharmaceutical company. Ms. Curran holds a Graduate Diploma of Marketing and a Bachelor of Applied Science (B.A.S.) from the University of Technology, Sydney. We believe Ms. Curran is qualified to serve on our Board of Directors because of her expertise in dermatology and years of experience in the pharmaceutical industry, including positions in senior executive roles at major pharmaceutical companies.

***Halley E. Gilbert*** has served as a member of our Board of Directors since May 2020. Ms. Gilbert is currently the Chief Operating Officer and Chief Legal Officer of Tubulis GmbH, an antibody drug conjugate oncology company, a position she has held since September 2025. Prior to Tubulis, Ms. Gilbert was Chief Legal Officer of CARGO Therapeutics, a cell therapy company focused on oncology indications until it was acquired by Concentra Biosciences in August 2025. From August 2021 through April 2022, Ms. Gilbert served as Chief Legal Officer of NeoGenomics Laboratories, a cancer diagnostics company. From July 2020 to August 2021, Ms. Gilbert served as Chief Operating Officer of Invivyd, Inc. (formerly,

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Adagio Therapeutics), a clinical stage company developing antibodies for infectious diseases. Prior to Invivyd, Ms. Gilbert held various roles at Ironwood Pharmaceuticals from February 2008 through February 2020, including Senior Vice President for Corporate Development, Chief Administrative Officer, and Chief Legal Officer. Prior to joining Ironwood Pharmaceuticals, Ms. Gilbert was Vice President, Deputy General Counsel at Cubist Pharmaceuticals, Inc. and previously served as a corporate counsel at Genzyme Corp., prior to its acquisition by Sanofi. She began her career at Skadden, Arps, Slate, Meagher & Flom LLP, where she specialized in mergers and acquisitions and securities law. Ms. Gilbert currently serves on the Board of Directors, including as chair of the nominating and corporate governance committee and a member of the audit committee, of each of Vaxcyte, Inc., a biopharmaceutical company developing vaccines for infectious disease targets, and CytomX Therapeutics, Inc., a biopharmaceutical company focused on the development of therapeutic cancer treatments. Ms. Gilbert previously served on the Board of Directors of Dermira, Inc. (acquired by Eli Lilly and Company), a commercial-stage company focused on medical dermatology, and Achaogen, Inc. (acquired by Cipla), a commercial-stage biopharmaceutical company that developed novel antibacterial therapies. Ms. Gilbert holds a B.A. in Political Science from Tufts University and J.D. from Northwestern University School of Law. We believe that Ms. Gilbert is qualified to serve on our Board of Directors because of her significant experience launching new medicines and her in-depth knowledge of legal matters, corporate and business development, compliance and government affairs from her extensive biopharmaceutical industry experience.

***Keith R. Leonard, Jr.*** has served as a member of our Board of Directors since September 2021 and has served as the Chair of our Board of Directors since November 2024. Mr. Leonard was previously chairman of the board of Unity Biotechnology Inc. where he served as chief executive officer from 2016 to 2020, and currently serves on the board of robotic surgery pioneer Intuitive Surgical. Previously, Mr. Leonard served as the chief executive officer of Kythera Biopharmaceuticals from its founding in 2005 to its acquisition by Allergan plc in 2015. Before Kythera, Mr. Leonard spent 13 years at Amgen, ultimately as senior vice president and general manager of Amgen Europe, where he ran all commercial operations in 28 countries. Prior to that position, Mr. Leonard ran Amgen's manufacturing operations in Europe, established Amgen's presence in inflammation, served as head of information management, and had leadership roles in sales and marketing, engineering, operations, and finance. Mr. Leonard previously served as an independent director of Sanifit Laboratories SA (a privately held clinical-stage biopharmaceutical company), Sienna Biopharmaceuticals, Inc., Anacor Pharmaceuticals, Inc., Affymax, Inc., and ARYx Therapeutics, and was a venture partner with ARCH Venture Partners. Mr. Leonard began his career as an officer in the Civil Engineer Corps of the U.S. Navy. He holds a Master of Business Administration from the Anderson School of Management, University of California, Los Angeles, a Master of Science in mechanical engineering from University of California, Berkeley, a Bachelor of Arts in history from University of Maryland, College Park, and a Bachelor of Science in engineering from University of California, Los Angeles. We believe Mr. Leonard is qualified to serve on the Board of Directors because of his years of experience as an executive in the pharmaceutical industry, his expertise in dermatology and deep commercial expertise.

**Directors Continuing in Office Until the 2028 Annual Meeting of Stockholders**

***Sue-Jean Lin*** has served as a member of our Board of Directors since June 2021 and has served as the Chair of the Audit Committee since September 2022. Ms. Lin retired in March 2025 from Alcon, where she held the position of Senior Vice President, Chief Information and Transformation Officer, and was a member of the Executive Committee. During her tenure at Alcon, she built and led a world-class global information technology organization and contributed to company's success after its spin-off from Novartis in 2019. From 2016 to 2018, she was a member of the Hill-Rom executive leadership team, serving in the capacity of senior vice president and chief information officer. In this role, she was instrumental in developing an innovative remote care in hospital acute care settings that enhanced patient engagement and improved the effectiveness of healthcare professionals. From 1989 to 2015, she held

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multiple roles at Allergan (prior to it being acquired by AbbVie Inc.), including as the senior vice president and chief information officer, and as the regional chief financial officer, VP of finance and controller, for Europe, Middle East, Africa, and Asia Pacific. Since June 2025, Ms. Lin has served on the board of Stevanato Group S.p.A., a public company specializing in drug containment and delivery solutions. Ms. Lin holds a bachelor's degree in accounting and a master's degree in business administration from the University of Nevada, Reno. She also holds a certificate in Effective AI Oversight from Carnegie Mellon University's Heinz College of Information Systems and Public Policy and the National Association of Corporate Directors, as well as a CERT Certificate in Cyber-Risk Oversight from Carnegie Mellon University's Software Engineering Institute, Ridge Global and the National Association of Corporate Directors. We believe Ms. Lin is qualified to serve on our Board of Directors because of her experience in senior executive positions in a number of industries, including healthcare, expertise in dermatology, and her financial, information technology, digital transformation, and cybersecurity expertise.

***Amit D. Munshi*** has served as a member of our Board of Directors and as the Chair of the Compensation Committee of the Board since December 2025. Since February 2026, Mr. Munshi has served as Interim Chief Executive Officer of Sensorion SA, a clinical-stage biotechnology company, where he has also been a board member since April 2025. Mr. Munshi was previously the President, Chief Executive Officer and as a board member of Orna Therapeutics, Inc., a biotechnology company, from May 2024 to April 2025. Prior to this, Mr. Munshi served as the President, Chief Executive Officer and as a board member of ReNAgade Therapeutics, Inc., an RNA therapeutics company, from May 2023 until its acquisition by Orna Therapeutics, Inc. in May 2024. Mr. Munshi previously served as the President and Chief Executive Officer of Arena Pharmaceuticals Inc., a then-publicly traded biopharmaceutical company, from May 2016 to March 2022, and a member of its Board of Directors from June 2016 until its acquisition by Pfizer in March 2022. Mr. Munshi was previously the Chief Executive Officer of Epirus Biopharmaceuticals, which filed for bankruptcy on July 25, 2016, and was previously Chief Executive Officer of Percivia LLC (acquired by Johnson & Johnson) and Chief Business Officer and co-founder of Kythera Biopharmaceuticals Inc. (acquired by Allergan). Mr. Munshi serves as a board member for a number of public biotechnology and pharmaceutical companies, including for Inhibikase Therapeutics, Inc. since October 2024, Zura Bio Limited and its predecessor since November 2022, and Galecto since May 2020. Mr. Munshi also previously served as a board member of Pulmatrix Inc., a publicly traded biopharmaceutical company from June 2017 until March 2021. Mr. Munshi holds a B.S. in Economics and a B.A. in History from the University of California, Riverside, and an M.B.A. from the Peter F. Drucker School of Management at Claremont Graduate University. We believe that Mr. Munshi is qualified to serve on our Board of Directors because of his expertise in financing, portfolio optimization, and strategic corporate transactions, combined with his experience advising diverse biotech companies and leading investment firms.

***Howard G. Welgus, M.D.*** has served as a member of our Board of Directors since August 2020. Dr. Welgus served as our Chief Medical Officer from April 2017 to July 2020. From February 2016 to June 2018, Dr. Welgus served as the Chief Medical Officer at Verrica Pharmaceuticals Inc. Prior to joining Verrica, Dr. Welgus served as the Chief Medical Officer at Thesan Pharmaceuticals Inc. from September 2012 to November 2016 and served as the Chief Medical Officer at Nycomed US Inc. from May 2009 to November 2010. From 1999 to 2009, he served as the Vice President and head of the Dermatology and Inflammation therapeutic areas in Discovery at Pfizer Inc. in Ann Arbor, MI. Prior to joining the private sector, Dr. Welgus was a faculty member at Washington University for 17 years. Dr. Welgus is a board-certified dermatologist and received a M.D. from Washington University School of Medicine in St. Louis and a B.A. in Biology from Rice University. We believe that Dr. Welgus is qualified to serve on our Board of Directors because of his extensive knowledge of our business, expertise in dermatology and his experience in the biopharmaceutical industry.

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**Board Recommendation**

**THE BOARD OF DIRECTORS RECOMMENDS A VOTE "*FOR"* THE ELECTION OF EACH OF THE THREE NAMED CLASS III DIRECTOR NOMINEES**

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**a**

**PROPOSAL NO. 2** 

**RATIFICATION OF SELECTION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM**

**Appointment of Independent Registered Public Accounting Firm**

The Audit Committee of our Board has engaged Ernst & Young LLP ("EY") as our independent registered public accounting firm for the year ending December 31, 2026, and is seeking ratification of such selection by our stockholders at the Annual Meeting. EY has served as the Company's independent registered public accounting firm since 2019. Representatives of EY are expected to be present at the Annual Meeting. They will have an opportunity to make a statement if they so desire and will be available to respond to appropriate questions.

Neither our bylaws nor other governing documents or law require stockholder ratification of the selection of EY as our independent registered public accounting firm. However, the Audit Committee is submitting the selection of EY to our stockholders for ratification as a matter of good corporate practice. If our stockholders fail to ratify the selection, the Audit Committee will reconsider whether or not to retain EY. Even if the selection is ratified, the Audit Committee in its discretion may direct the appointment of a different independent registered public accounting firm at any time during the year if they determine that such a change would be in the best interests of the Company and our stockholders.

**Principal Accountant Fees and Services**

The following table provides information regarding the fees incurred for services related to the fiscal years ended December 31, 2025 and 2024, by EY, our independent registered public accounting firm.

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| | | |
|:---|:---|:---|
| | **Year Ended December 31,** | **Year Ended December 31,** |
| | **2025** | **2024** |
| Audit Fees (1) | $1937370 | $2242058 |
| Tax Fees (2) | 177882 | 131114 |
| Audit-Related Fees |  |  |
| All Other Fees (3) | 3600 | 3600 |
| **Total Fees** | $**2118852** | $**2376772** |

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(1)Audit fees are for professional services rendered for the audits of our annual financial statements; the audits of our internal controls; the reviews of our interim financial statements; professional services rendered in connection with our registration statements and securities offerings; and the issuance of comfort letters and consents.

(2)Tax Fees include professional services in connection with tax compliance and consulting services.

(3)All Other Fees include fees for accounting research and reporting tools.

The Committee concluded that the provision of these services by EY would not affect their independence.

**Pre-Approval Policies and Procedures**

The Audit Committee has adopted a policy (the "Pre-Approval Policy") that sets forth the procedures and conditions pursuant to which audit and non-audit services proposed to be performed by the independent registered public accounting firm may be pre-approved. The Pre-Approval Policy provides that annual audit services engagement terms and fees are subject to the approval of the Audit Committee and delegates certain authority to the Chair of the Audit Committee to approve audit, audit-related, tax or permissible non-audit services, provided that the delegated services do not exceed 10% of the prior year actual costs for annual services provided by the independent registered public accounting firm, as established by the Audit Committee. Any services above the 10% limit require the approval of the

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full Audit Committee. The Pre-Approval Policy also provides that each pre-approval decision shall be communicated to the Audit Committee at its next scheduled meeting.

The Audit Committee considers whether services proposed to be performed by the independent registered public accounting firm are consistent with the SEC's rules on auditor independence. The Audit Committee will also consider whether the independent auditor is best positioned to provide the most effective and efficient service.

In connection with the Pre-Approval Policy, the Audit Committee will monitor the audit services engagement as necessary, and will approve, if necessary, any changes in terms, conditions and fees resulting from changes in audit scope, Company structure or other items.

All services to the Company provided by the Company's independent registered public accounting firm after the adoption of the Pre-Approval Policy in 2022 were approved in accordance with the Pre-Approval Policy.

**Board Recommendation**

**THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" RATIFICATION OF OUR SELECTION OF ERNST & YOUNG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR THE YEAR ENDING DECEMBER 31, 2026.**

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**a**

**AUDIT COMMITTEE REPORT**

The material in this report is not "soliciting material," is not deemed "filed" with the SEC, and is not to be incorporated by reference into any filing of Arcutis Biotherapeutics, Inc. under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended.

The primary purpose of the Audit Committee is to oversee our financial reporting processes on behalf of our Board. The Audit Committee's functions are more fully described in its charter, which is available on our website at https://investors.arcutis.com/corporate-governance/governance-overview. Management has the primary responsibility for our financial statements and reporting processes, including our systems of internal controls.

In fulfilling its oversight responsibilities, the Audit Committee reviewed and discussed with management the Company's audited financial statements as of and for the year ended December 31, 2025. The Audit Committee has discussed with Ernst & Young LLP ("EY"), the Company's independent registered public accounting firm, the matters required to be discussed by the applicable requirements of, Communications with Audit Committees, as adopted by the Public Company Accounting Oversight Board ("PCAOB") and the SEC.

In addition, the Audit Committee has received the written disclosures and the letter from EY required by PCAOB Ethics and Independence Rule 3526, "Communication with Audit Committees Concerning Independence", and the Audit Committee has discussed with EY their independence from the Company and its management. Finally, the Audit Committee discussed with EY, with and without management present, the scope and results of EY's audit of such financial statements.

Based on these reviews and discussions, the Audit Committee has recommended to our Board that such audited financial statements be included in our Annual Report on Form 10-K for the year ended December 31, 2025 for filing with the SEC. The Audit Committee has selected EY as our independent registered public accounting firm for the fiscal year ending December 31, 2026, and is seeking ratification of such selection by the stockholders.

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| |
|:---|
| **Audit Committee** |
| Sue-Jean Lin, Chair |
| Neha Krishnamohan |
| Halley Gilbert |

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**EXECUTIVE OFFICERS**

The following is biographical information for our executive officers, including their ages as of April 8, 2026:

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| | | |
|:---|:---|:---|
| **Name** | **Age** | **Position(s)** |
| Todd Franklin Watanabe | 58 | President, Chief Executive Officer and Director |
| Patrick E. Burnett, M.D., Ph.D. | 54 | Executive Vice President and Chief Medical Officer |
| Masaru Matsuda, JD | 56 | Executive Vice President, Chief Legal Officer and Corporate Secretary |
| L. Todd Edwards | 62 | Executive Vice President and Chief Commercial Officer |
| Latha Vairavan | 48 | Senior Vice President and Chief Financial Officer |

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Mr. Watanabe's biographical information is included above under "Directors Continuing in Office Until the 2026 Annual Meeting of Stockholders."

***Patrick E. Burnett, M.D., Ph.D.*** has served as our Executive Vice President and Chief Medical Officer since December 2024 and prior as Senior Vice President and Chief Medical Officer since August 2020. Prior to that Dr. Burnett was the Chief Medical Officer at Verrica Pharmaceuticals since April 2018. Prior to that, Dr. Burnett was at Sun Pharmaceuticals where he was Associate Vice President of Clinical Development from September 2015 to March 2018, with oversight of the dermatology and rheumatology pipeline. Prior to Sun Pharmaceuticals, Dr. Burnett was at Novartis from 2010 to August 2015, most recently as Global Program Medical Director. He is a board certified dermatologist and was a member of the medical faculty at Vanderbilt University Medical Center as an Assistant Professor of Dermatology from 2004 to 2010. Dr. Burnett holds an M.D. and Ph.D. in neuroscience from Johns Hopkins School of Medicine and a B.S. in Biology and Biochemistry from the University of Iowa.

***Masaru Matsuda, JD*** has served as our Executive Vice President, Chief Legal Officer and Corporate Secretary since March 2026 and prior as Senior Vice President, General Counsel and Corporate Secretary since January 2022. Mr. Matsuda most recently served as Senior Vice President, General Counsel, Chief Compliance Officer, and Corporate Secretary at Halozyme Therapeutics, Inc., where he worked from August 2018 through December 2021. Prior to Halozyme, Mr. Matsuda worked at Amgen for 18 years in positions of increasing responsibility with his last role serving as Vice President, Law, Global Commercial Operations, where he was responsible for strategic commercial legal support to the US Commercial Operations organization, as well as Medical Affairs, Compliance, Global Value, Access & Policy, Global Marketing, and Biosimilars divisions. Mr. Matsuda received a B.S. in Business Administration with a dual emphasis in Corporate Finance and International Finance from the University of Southern California, and J.D. from University of California College of the Law, San Francisco.

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***L. Todd Edwards*** has served as our Executive Vice President and Chief Commercial Officer since December 2024 and prior as Senior Vice President and Chief Commercial Officer since September 2023. Prior to joining the Company, Mr. Edwards served as Group Vice President, Business Head, Immunology at Incyte Corporation ("Incyte"), a multinational pharmaceutical company, since December 2020, where he was responsible for the commercialization of assets in Incyte's dermatology business unit. Prior to Incyte, Mr. Edwards worked at UCB S.A., a global biopharmaceutical company, in a variety of capacities. From June 2019 to December 2020, Mr. Edwards served as Senior Vice President and Head of Global Immunology Operations and Strategy, during which time he led the global immunology business unit and portfolio. From June 2013 to June 2019, Mr. Edwards served as Senior Vice President and Head of U.S. Immunology, during which time he led the organization's development and commercialization of on-market injectable biologic and pipeline immunology products in rheumatology, dermatology and gastroenterology. Prior to that, Mr. Edwards held senior roles at AbbVie and TAP Pharmaceuticals. In addition, Mr. Edwards is a decorated veteran of the U.S. Army. Mr. Edwards received a B.S. in Psychology from the East Tennessee State University and an M.B.A. from Embry-Riddle Aeronautical University.

***Latha Vairavan*** has served as our Senior Vice President and Chief Financial Officer since May 2025 and prior as Vice President, Finance and Corporate Controller since August 2024. She joined the Company in March 2020 and previously held positions as Vice President of Finance and Investor Relations and Executive Director, Financial Planning and Analysis. Prior to that, Ms. Vairavan worked at Amgen Inc. for 12 years, where she held various roles of increasing responsibility within the finance organization, culminating as Finance Director for US Value and Access. Ms. Vairavan started her career as a financial consultant working for accounting firms KPMG and Arthur Andersen. She holds a B.S. in Business Administration, Finance from the University of Southern California and is a licensed CPA in California.

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**CORPORATE GOVERNANCE**

**Code of Business Conduct and Ethics**

We have adopted a Code of Conduct and Ethics that applies to all of our employees, officers and directors, including those officers responsible for financial reporting. The Code of Conduct and Ethics is available on our website at https://investors.arcutis.com/corporate-governance/governance-overview. The Audit Committee and Nominating and Corporate Governance Committee are responsible for the development and periodic review of the Code of Conduct and Ethics. We expect that any amendments to the code, or any waivers of its requirements, will be disclosed on our website.

**Corporate Governance Guidelines**

We believe in sound corporate governance practices and have adopted formal Corporate Governance Guidelines to enhance our effectiveness. Our Board adopted these Corporate Governance Guidelines in order to ensure that it has the necessary practices in place to review and evaluate our business operations as needed and to make decisions that are independent of our management. The Corporate Governance Guidelines are also intended to align the interests of directors and management with those of our stockholders. The Corporate Governance Guidelines set forth the practices our Board follows with respect to Board and committee composition and selection, Board meetings, Chief Executive Officer performance evaluation and succession planning. A copy of our Corporate Governance Guidelines is available on our website at https://investors.arcutis.com/corporate-governance/governance-overview.

**Leadership Structure of the Board**

Our Bylaws and Corporate Governance Guidelines provide our Board with flexibility to combine or separate the positions of Chair of the Board and Chief Executive Officer and/or to implement a lead director in accordance with its determination that utilizing one or the other structure would be in the best interests of the Company. Mr. Leonard currently serves as the Chair of our Board. In that role, Mr. Leonard presides over the executive sessions of the Board and as a liaison between management and the Board. All of our directors are encouraged to make suggestions for agenda items and pre-meeting materials for meetings of the Board.

Our Board has determined that it is in Arcutis's best interest to maintain a separate Chair of the Board and Chief Executive Officer. Our Board believes that separating these roles enhances its independent oversight of management and that a separate Chair of the Board can more effectively lead the Board in objectively evaluating the performance of management, including the Chief Executive Officer. Our Board has concluded that our current leadership structure is appropriate at this time. However, our Board will continue to periodically review our leadership structure and may make such changes in the future as it deems appropriate.

**Independence of the Board of Directors**

As required under the Nasdaq Global Select Market ("Nasdaq") rules and regulations, a majority of the members of a listed company's Board of Directors must qualify as "independent," as affirmatively determined by such board. The Board consults with the Company's counsel to ensure that the Board's determinations are consistent with all relevant securities and other laws and regulations regarding the definition of "independent," including those set forth in pertinent Nasdaq listing standards, as in effect from time to time.

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Consistent with these considerations, our Board has determined that eight of our nine directors qualify as "independent" directors in accordance with the Nasdaq listing requirements. Mr. Watanabe is not considered independent because he is an employee of the Company. The Nasdaq independence definition includes a series of objective tests, such as that the director is not, and has not been for at least three years, one of our employees and that neither the director nor any of his or her family members has engaged in various types of business dealings with us. In addition, as required by Nasdaq rules, our Board has made a subjective determination as to each independent director that no relationships exist, which, in the opinion of our Board, would interfere with the exercise of independent judgment in carrying out the responsibilities of a director. In making these determinations, our Board considered information provided by the directors and us with regard to each director's business and personal activities and relationships as they may relate to us and our management. There are no family relationships among any of our directors or executive officers.

As required under Nasdaq rules and regulations, our independent directors meet in regularly scheduled executive sessions at which only independent directors are present. Each of the Audit Committee and Compensation Committee of our Board are comprised entirely of directors determined by the Board to be independent within the meaning of Nasdaq and SEC rules and regulations applicable to the members of such committees. Each of the members of our Nominating and Corporate Governance Committee is an independent director under the applicable rules and regulations of Nasdaq relating to Nominating and Corporate Governance Committee independence. As a result, in accordance with Nasdaq Rule 5605(e), director nominees are selected, or recommended for the Board's selection, by the independent directors constituting a majority of the Board's independent directors in a vote in which only independent directors participate.

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**Board Skills Overview**

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| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Curran** | **Gilbert** | **Heron** | **Krishnamohan** | **Leonard** | **Lin** | **Munshi** | **Watanabe** | **Welgus** |
| ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** | ***Skills & Expertise*** |
| **Executive Management** | ● | ● | | ● | ● | ● | ● | ● | ● |
| Served as CEO or other senior executive of an organization | ● | ● | | ● | ● | ● | ● | ● | ● |
| **Public Board Experience** | ● | ● | ● | | ● | ● | ● |  | |
| Experience as a director of another public company | ● | ● | ● | | ● | ● | ● |  | |
| **Veteran** | | | | | ● | | | ● | |
| Experience serving as a member of the U.S. military, naval or air services | | | | | ● | | | ● | |
| **Dermatology** | ● | ● | ● | | ● | ● | ● | ● | ● |
| Prior significant business experience in dermatology | ● | ● | ● | | ● | ● | ● | ● | ● |
| **Finance & Accounting Expertise** | | ● | ● | ● | | ● | | | |
| Experience in the preparation and review of financial statements and financial reports | | ● | ● | ● | | ● | | | |
| **Commercialization Expertise** | ● | ● | | | ● | | ● | ● | ● |
| Experience managing the successful commercialization of products | ● | ● | | | ● | | ● | ● | ● |
| **Information Technology** | | | | | ● | ● | | | |
| Oversight of or significant background working with information technology systems, data management, and/or cybersecurity risks | | | | | ● | ● | | | |
| **Legal / Compliance Expertise** | | ● | | ***●*** | | | | | |
| Experience in dealing with complex legal, compliance and public company governance issues | | ● | | ***●*** | | | | | |
| **Capital Markets and Strategic Transactions** | ***●*** | ***●*** | ***●*** | **●** | ***●*** | | ***●*** | ***●*** | |
| Experience with capital markets and strategic corporate transactions, including M&A. | ***●*** | ***●*** | ***●*** | **●** | ***●*** | | ***●*** | ***●*** | |
| ***Gender*** | | | | | | | | | |
| **Gender** | F | F | M | F | M | F | M | M | M |

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**Board Committees**

Our Board has the following standing committees: an Audit Committee, a Compensation Committee, and a Nominating and Corporate Governance Committee. Our Board may establish other committees to facilitate the management of our business. The composition and functions of each committee are described below.

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*Audit Committee*

Our Audit Committee oversees our corporate accounting and financial reporting process. Among other matters, the Audit Committee is responsible for:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• selecting an independent registered public accounting firm;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the qualifications, independence and performance of our registered public accounting firm;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the preparation of the audit committee report to be included in our annual proxy statement;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• our compliance with legal and regulatory requirements;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• our accounting and financial reporting processes, including our financial statement audits and the integrity of our financial statements;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the performance of our internal audit function;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• reviewing and approving related-person transactions; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• our information technology and information security, data privacy and cybersecurity programs.

The current members of our Audit Committee are Sue-Jean Lin, Neha Krishnamohan and Halley Gilbert. Ms. Lin serves as the Chair of the committee. All members of our Audit Committee meet the requirements for financial literacy under the applicable rules and regulations of the SEC and Nasdaq. Our Board has determined that each of Sue-Jean Lin, Neha Krishnamohan and Halley Gilbert are an "audit committee financial expert" as defined under the applicable rules of the SEC and has the requisite financial sophistication as defined under the applicable rules and regulations of Nasdaq. Under the rules of the SEC, members of the audit committee must also meet heightened independence standards. Our Board has determined that each of Ms. Lin, Ms. Krishnamohan and Ms. Gilbert are independent under the applicable rules of the SEC and Nasdaq.

The Audit Committee operates under a written charter that satisfies the applicable standards of the SEC and Nasdaq. A copy of the Audit Committee charter is available to security holders on the Company's website at https://investors.arcutis.com/corporate-governance/governance-overview.

*Compensation Committee*

Our Compensation Committee oversees policies relating to compensation of and benefits for our officers and employees. Among other things, our Compensation Committee is responsible for:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• evaluating, recommending, approving and reviewing executive officer compensation arrangements, plans, policies and programs;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• evaluating and recommending non-employee director compensation arrangements for determination by our Board;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• administering our cash-based and equity-based compensation plans;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• reviewing and overseeing the administration of our clawback policy, stock ownership policies and recommending any proposed changes to the Board; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• overseeing our compliance with regulatory requirements associated with the compensation of directors, officers and employees.

The current members of our Compensation Committee are Patrick Heron, Keith Leonard and Amit Munshi. Mr. Munshi serves as the Chair of the committee. Each of the members of our

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Compensation Committee is independent under the applicable rules and regulations of Nasdaq and is a "non-employee director" as defined in Rule 16b-3 promulgated under the Exchange Act.

Our Compensation Committee has retained Pay Governance LLC ("Pay Governance"), a compensation consulting firm, to serve as its independent compensation consultant and to conduct market research and analysis on our various executive positions, to assist the committee in developing appropriate incentive plans for our executives on an annual basis, to provide the committee with advice and ongoing recommendations regarding material executive compensation decisions, and to review compensation proposals of management. Pay Governance reports directly to the Compensation Committee and does not provide any non-compensation related services to the Company. The Compensation Committee reviewed the independence of Pay Governance, employing the independence factors specified in the listing requirements of Nasdaq. Based on this assessment, the Compensation Committee determined that the engagement of Pay Governance does not raise any conflicts of interest or similar concerns. In addition, the Compensation Committee evaluated the independence of its other outside advisors to the Compensation Committee, including outside legal counsel, considering the same independence factors and concluded their work for the Compensation Committee does not raise any conflicts of interest.

The Compensation Committee operates under a written charter that satisfies the applicable standards of the SEC and The Nasdaq rules. A copy of the Compensation Committee charter is available to security holders on the Company's website at https://investors.arcutis.com/corporate-governance/governance-overview.

*Nominating and Corporate Governance Committee*

Among other things, our Nominating and Corporate Governance Committee is responsible for:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• identifying and considering candidates for directorships;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the size and composition of our Board;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• overseeing the process of evaluating the performance of our Board;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• reviewing and approving any related person transactions where any member of the Audit Committee is a related person;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• evaluating and overseeing our environmental, social and governance principles, initiatives and risks focusing on the Company's strategy and initiatives regarding clinical trial quality, product safety, patient access and affordability, human capital management, sustainable operations, and corporate governance practices; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• reporting and advising our Board on other corporate governance matters.

The current members of our Nominating and Corporate Governance Committee are Terrie Curran, Sue-Jean Lin, and Howard Welgus, M.D. Ms. Curran serves as the Chair of the committee. Each of the members of our Nominating and Corporate Governance Committee is an independent director under the applicable rules and regulations of Nasdaq relating to Nominating and Corporate Governance Committee independence. As a result, in accordance with Nasdaq Rule 5605(e), director nominees are selected, or recommended for the Board's selection, by the independent directors constituting a majority of the Board's independent directors in a vote in which only independent directors participate. In carrying out its responsibilities, the Nominating and Corporate Governance Committee operates under a written charter that satisfies the applicable standards of the SEC and Nasdaq rules. A copy of the Nominating and Corporate Governance Committee charter is available to security holders on the Company's website at https://investors.arcutis.com/corporate-governance/governance-overview.

Our Nominating and Corporate Governance Committee is responsible for reviewing with the Board, on an annual basis, the appropriate characteristics, skills and experience required for the Board as a whole and its individual members. The Nominating and Corporate Governance Committee, in

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evaluating the suitability of individual candidates (both new candidates and current members), the independent directors of our Board, in recommending candidates for election, and the Board, in approving (and, in the case of vacancies, appointing) such candidates, may take into account many factors, including but not limited to the following:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• independence;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• personal and professional integrity;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• experience in corporate management, such as serving as an officer or former officer of a publicly held company;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• experience in the life sciences and biotechnology fields;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• experience as a board member or executive officer of another publicly held company;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• background and range of expertise, skills and experience in substantive matters pertaining to our business relative to other Board members;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• conflicts of interest; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• practical and mature business judgment.

Currently, our Board evaluates each individual in the context of the Board as a whole, with the objective of assembling a group that can best maximize the success of the business and represent stockholder interests through the exercise of sound judgment using its diversity of experience in these various areas. Our Board will consider director candidates recommended by stockholders. For a stockholder to make any nomination for election to the Board at an annual meeting, the stockholder must provide notice to the Company, which notice must be delivered to, or mailed and received at, the Company's principal executive offices not less than 75th day and not more than 105th day prior to the one-year anniversary of the preceding year's annual meeting; provided, that if the date of the annual meeting is more than 30 days before or more than 60 days after such anniversary date, the stockholder's notice must be delivered, or mailed and received, not earlier than 105th day prior to the date of the annual meeting and not later than 75th day prior to the date of the annual meeting or, if later, the 10th day following the date on which public disclosure of the date of such annual meeting is made. Further updates and supplements to such notice may be required at the times, and in the forms, required under our bylaws. As set forth in our bylaws, submissions must include information regarding the proposed nominee that is required to be disclosed in a proxy statement or other filings in a contested election pursuant to Section 14(a) under the Exchange Act, (including such person's written consent to being named in the proxy statement as a nominee and to serving as a director if elected). Our bylaws also specify further requirements as to the form and content of a stockholder's notice. We recommend that any stockholder wishing to make a nomination for director review a copy of our bylaws, as amended and restated to date, which is available, without charge, from our Corporate Secretary, at 3027 Townsgate Road, Suite 300, Westlake Village, CA 91361.

**Meetings of the Board of Directors, Board and Committee Member Attendance and Annual Meeting Attendance**

Our Board met six times during 2025. The Audit Committee met five times. The Compensation Committee met five times. The Nominating and Corporate Governance Committee met four times. During 2025, each Board member attended at least 75% of the meetings of the Board and of the committees of the Board on which he or she served, in each case, to the extent appointed as a Board member at the relevant time of each meeting. We encourage all of our directors and nominees for director to attend our annual meeting of stockholders; however, attendance is not mandatory. Eight directors attended the annual meeting of stockholders held in 2025.

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**Role of Board in Risk Oversight Process**

Risk assessment and oversight are an integral part of our governance and management processes. Our Board encourages management to promote a culture that incorporates risk management into our corporate strategy and day-to-day business operations. Management discusses strategic and operational risks at regular management meetings, and conducts specific strategic planning and review sessions during the year that include a focused discussion and analysis of the risks facing us. Senior management reviews these risks with the Board as part of regular Board meetings that focus on particular business functions, operations or strategies and discusses the steps taken by management to mitigate or eliminate such risks.

Our Board does not have a standing risk management committee, but rather administers this oversight function directly through our Board as a whole, as well as through various standing committees of our Board that address risks inherent in their respective areas of oversight. We complete an annual enterprise-wide risk assessment to identify the primary risks that could impede us from achieving our strategic objectives. The risk assessment follows a disciplined approach and includes interviews with senior leadership to identify and assess the significance of enterprise-wide risks at the Company. Such identification and assessment facilitates planning and accountability on how to manage and ameliorate such risks, and we will update the assessment at least annually. While our Board is responsible for monitoring and assessing strategic risk exposure, our Audit Committee is responsible for overseeing our major financial risk exposures and the steps our management has taken to monitor and control these exposures. We present and discuss our enterprise-risk assessment and planned mitigation plan at least annually with the Audit Committee. The Audit Committee also monitors compliance with legal and regulatory requirements and considers and approves or disapproves any related person transactions. Our Nominating and Corporate Governance Committee monitors the effectiveness of our corporate governance guidelines and considers and approves or disapproves any related person transactions where any member of the Audit Committee is a related party in such a transaction. Our Compensation Committee assesses and monitors whether any of our compensation policies and programs has the potential to encourage excessive risk-taking.

**Our Capital Management, Product Access and Environmental Impact Philosophies and Principles**

From the initial founding of Arcutis, we have strived to create an environment where workforce development, product innovation and quality, and sustainability are integrated into all aspects of our operations. This is evidenced by the clinical trials, treatments, and programs we have developed to meet unmet needs of individuals impacted by immune-mediated skin disease and their healthcare providers, the talent and diverse experience of our employees and our strong commitment to our community and the environment.

**Governance**

The Nominating and Corporate Governance Committee is charged with evaluating and overseeing our environmental, social and governance principles, initiatives, and risks, focusing on the Company's strategy and initiatives regarding clinical trial quality, product safety, patient access and affordability, human capital management, sustainable operations, and corporate governance practices. Where appropriate, these matters are also discussed within the Audit and Compensation committees and are reviewed with the Board on an as-needed basis. Internal oversight and execution is managed with a cross-functional team led by our Chief Digital and Information Technology Officer, and includes our Chief Legal Officer, Chief Human Resources Officer, Head of Corporate Communications, and Head of Investor Relations.

**Our Commitment to Our People**

Our employees are essential to our ability to develop innovative therapeutics, and our workforce development efforts make our company stronger. We value our employees and take care of them in multiple ways, including through competitive compensation, comprehensive benefits and retirement plans,

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a flexible workplace policy, health and safety training programs and job skills, compliance and leadership training. We strive to create an inclusive working environment that allows us to recruit and retain the best qualified people, and we are proud of the culture we have created. We are committed to a culture where everyone can contribute, regardless of their background.

**Pay Equity Assessment**

As part of our commitment to pay equity and equality for all employees, we have committed to conducting an annual pay equity assessment to identify and address potential pay gaps. In our 2025 assessment conducted in January 2026 for United States employees below the Senior Vice President level, no evidence of a systemic pay equity issue was found. More information on this assessment can be found in the Executive Compensation section of this proxy.

**Professional Development**

At Arcutis, we invest in building a high-performing, growth-oriented workforce by providing employees with opportunities to continuously develop their skills, capabilities, and leadership effectiveness. Our professional development strategy, ProfDev@Arcutis, is designed to foster a culture of learning, strengthen organizational effectiveness, and enable leaders at all levels. Our intentional approach is anchored in three core areas:

**Grow (Career Development)**

Support employees in ongoing development through Individual Development Plans, manager tools, and learning elective programs.

**Connect (Organizational Effectiveness)**

Enhance collaboration and communication through shared experiences such as Insights® Discovery workshops, team-based learning, and a Mentorship Exchange Program that fosters knowledge sharing, cross functional collaboration, and employee connection.

**Lead (Leadership Development)**

Build leadership capability through structured programs for emerging, first-line, and senior leaders, supported by performance management, coaching, and feedback processes.

We continue to scale these efforts as our organization grows. Since launching in 2021:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• 100% of employees participate in Insights® Discovery and structured performance and development cycles

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Approximately 40% of employees have engaged in a formal Leadership Development Program (Emerging, First-Line, or Senior Leader)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Our Emerging Leader Development Program, launched in 2024, strengthens our internal leadership pipeline by preparing high-potential talent for future people leadership roles

These programs are supported by an integrated performance and development platform, reinforcing a consistent and scalable approach to employee growth, leadership development, and organizational effectiveness.

**Arcutis Culture Team and Community Engagement**

Since 2020, our Arcutis Culture Team (ACT) helps plan and coordinate employee engagement activities. ACT is a cross-functional working group designed to integrate and facilitate the education of our employees and provide opportunities to strengthen our employee community. ACT is organized into various sub-teams focused on engagement, charity, and community initiatives. In 2025, our team contributed more than 2,000 volunteer hours to organizations across the United States and provided

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monetary support to 92 nonprofit organizations representing a wide range of philanthropic causes. As a company, we proudly supported national organizations, such as the National Psoriasis Foundation and the American Academy of Dermatology, while also partnering with local nonprofits, including Manna Food Bank, Casa Pacifica's Foster Youth Program, Many Mansions, the National Alliance on Mental Illness, Vitalant Blood Drive, and the One Warm Coat Drive, among many others.

**Health and Safety**

We are also focused on the health, well-being and safety of our employees. Our policies seek to prevent and reduce workplace risks and injuries. Employee safety is also supported by an access control system and 24/7 video monitoring at our offices in Westlake Village. We require all work-related injuries or illnesses to be reported. This information is reviewed by management for analysis.

**Access to and Affordability of Our Product**

Providing access to our product is paramount to our business. Our patient assistance program, Arcutis Cares™, provides Zoryve<sup>®</sup> (roflumilast) cream 0.3%, Zoryve<sup>®</sup> (roflumilast) foam 0.3%, Zoryve<sup>®</sup> (roflumilast) cream 0.15% and Zoryve<sup>®</sup> (roflumilast) cream 0.05% at no cost to eligible uninsured or underinsured patients with plaque psoriasis, seborrheic dermatitis or atopic dermatitis with demonstrated financial need. ZORYVE Direct™, a patient access support program, helps commercially insured individuals with plaque psoriasis, seborrheic dermatitis or atopic dermatitis by providing prescription status updates, refill reminders, and information to help patients stay on track with ZORYVE as prescribed by their healthcare provider. It also helps with out-of-pocket costs for eligible patients with commercial drug insurance.

**Environmental**

We have initiated an assessment of our greenhouse gas emissions footprint, in order to develop a methodology for collection and reporting. Through internal resources and third-party relationships, we are confident in our ability to quantify our scope 1 and 2 emissions while continuing to evaluate and understand our supply chain. We have also worked with our third-party suppliers to understand their sustainability practices. In addition, we have limited our operational environmental footprint by operating in a hybrid and virtual work environment. Our policies and work habits encourage environmentally conscious activities, such as reduced printing, automatic lights and water taps, recycling, and the elimination of single-use items in the break room. We believe these policies have helped to reduce waste generated through our operations.

**Compensation Committee Interlocks and Insider Participation**

During 2025, our Compensation Committee consisted of Dr. Bhaskar Chaudhuri, Mr. Heron and Mr. Leonard. In December 2025, Dr. Chaudhuri retired, and Mr. Munshi was appointed Chair of the Compensation Committee. None of the members of our Compensation Committee has been one of our officers or employees during the past three years. With the exception of Mr. Watanabe who serves as our President, Chief Executive Officer and a director, none of our executive officers currently serve, or in the past fiscal year has served, as a member of the Board of Directors or compensation committee of any entity that has one or more executive officers on our Board or Compensation Committee.

**Pledging and Hedging Policies** 

We maintain an Insider Trading Compliance Policy that prohibits our employees, officers and directors from engaging in hedging or similar monetization transactions, including put options, call options, short sales and exchange fund transactions. Our policy also prohibits employees, officers and directors from using or pledging securities as collateral in margin accounts or for loans unless approved by our designated compliance officer under the policy.

**Stockholder Communications with the Board of Directors**

Should stockholders wish to communicate with the Board or any specified individual directors, such correspondence should be sent to the attention of the Corporate Secretary, at 3027 Townsgate Road,

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Suite 300, Westlake Village, CA 91361. The Corporate Secretary will forward the communication to the Board members.

**CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS**

We describe below transactions and series of similar transactions, since January 1, 2025, to which we were a party or will be a party, in which:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• the amounts involved exceeded or will exceed $120,000; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• any of our directors, executive officers or holders of more than 5% of our common stock, or an affiliate or immediate family member thereof, had or will have a direct or indirect material interest.

**Director and Executive Officer Compensation**

See "Executive Compensation" and "Director Compensation" for information regarding compensation of directors and executive officers.

**Employment Agreements**

We have entered into employment agreements with our executive officers. We most recently entered into a new severance and change in control agreement with Ms. Vairavan in connection with her appointment as Senior Vice President and Chief Financial Officer in April 2025. For more information regarding these agreements, see "Executive Compensation - Employment and Severance Agreements."

**Director Transition**

In connection with Mr. Bhaskar Chaudhuri's resignation from our Board, we entered into a transition and consulting agreement with Mr. Chaudhuri, effective December 3, 2025. Pursuant to the terms of the agreement, Mr. Chaudhuri will be available to provide transition-related services to the Company as a consultant, including supporting product development of topical dermatology products, process and manufacturing matters for development and commercial products, and other tasks reasonably requested by the Board. Mr. Chaudhuri will be available to provide consulting services through June 30, 2027 at a rate of $1,000 per hour, and his equity awards will continue to vest during the consulting period. Our Board, including all Audit Committee members, approved the terms of the transition and consulting agreement with Mr. Chaudhuri.

**Indemnification Agreements and Directors' and Officers' Liability Insurance**

We have entered into indemnification agreements with each of our directors and executive officers. These agreements, among other things, require us to indemnify each director and executive officer to the fullest extent permitted by Delaware law, including indemnification of expenses such as attorneys' fees, judgments, penalties, fines and settlement amounts incurred by the director or executive officer in any action or proceeding, including any action or proceeding by or in right of us, arising out of the person's services as a director or executive officer. We have obtained an insurance policy that insures our directors and officers against certain liabilities, including liabilities arising under applicable securities laws. Since January 1, 2025, we have entered into new indemnification agreements in connection with the appointment of Ms. Vairavan as our Senior Vice President and Chief Financial Officer and the appointment of Mr. Munshi to our Board.

**Investor Rights Agreement**

We entered into an amended and restated investors' rights agreement with the purchasers of shares of our convertible preferred stock, including entities with which certain of our directors are affiliated, which were outstanding prior to our initial public offering in January 2020 and which converted into shares of common stock in connection therewith. As of December 31, 2025, certain holders of our

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common stock are entitled to rights with respect to the registration of their shares under the Securities Act.

**Policies and Procedures for Related Party Transactions**

Our Board has adopted a written related person transaction policy setting forth the policies and procedures for the review and approval or ratification of related person transactions. This policy covers, with certain exceptions set forth in Item 404 of Regulation S-K under the Securities Act of 1933, as amended, any transaction, arrangement or relationship, or any series of similar transactions, arrangements or relationships in which we were or are to be a participant, where the amount involved exceeds $120,000 and a related person had or will have a direct or indirect material interest, including, without limitation, purchases of goods or services by or from the related person or entities in which the related person has a material interest, indebtedness, guarantees of indebtedness and employment by us of a related person. In reviewing and approving any such transactions, our Audit Committee is tasked to consider all relevant facts and circumstances, including, but not limited to, whether the transaction is on terms comparable to those that could be obtained in an arm's length transaction with an unrelated third party and the extent of the related person's interest in the transaction. Our Nominating and Corporate Governance Committee reviews and approves any related person transactions where any member of the Audit Committee is a related party.

**EXECUTIVE COMPENSATION**

**COMPENSATION DISCUSSION AND ANALYSIS**

In this Compensation Discussion and Analysis ("CD&A") set forth below, we provide an overview and analysis of the compensation awarded to or earned by our named executive officers (collectively, the "named executive officers" or "NEOs") during fiscal 2025, including the elements of our compensation program for named executive officers, material compensation decisions made under that program for fiscal 2025 and the material factors considered in making those decisions. Our named executive officers for the year ended 2025, which consist of our principal executive officer, our principal financial officer, our three other most highly compensated executive officers for fiscal year 2025, and our former principal financial officer, are:

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| | |
|:---|:---|
| **Name** | **Position** |
| Todd Franklin Watanabe | President and Chief Executive Officer |
| Latha Vairavan | Senior Vice President, Chief Financial Officer |
| Patrick Burnett, M.D., Ph.D. | Executive Vice President, Chief Medical Officer |
| L. Todd Edwards | Executive Vice President, Chief Commercial Officer |
| Masaru Matsuda, J.D. | Executive Vice President, Chief Legal Officer |
| David Topper | Former Chief Financial Officer |

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Ms. Vairavan commenced services as our Senior Vice President and Chief Financial Officer on May 6, 2025, replacing Mr. Topper who served as our Chief Financial Officer until May 6, 2025 and continued employment until his retirement on May 15, 2025.

This discussion may contain forward-looking statements that are based on our current plans, considerations, expectations and determinations regarding future compensation programs. Actual compensation programs that we adopt following this proxy statement may differ materially from currently planned programs as summarized in this discussion.

**Executive Summary**

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We are a commercial-stage biopharmaceutical company focused on developing and commercializing treatments for dermatological diseases with high unmet medical needs. Our current portfolio is comprised of highly differentiated topical and systemic treatments with significant potential to treat immune-mediated dermatological diseases and conditions. We believe we have built a leading platform for dermatologic product development and commercialization. Our strategy is to focus on validated biological targets, and to use our drug development platform and deep dermatology expertise to develop and commercialize differentiated products that have the potential to address the major shortcomings of existing therapies in our targeted indications. We believe this strategy uniquely positions us to rapidly advance our goal of bridging the treatment innovation gap in dermatology, while maximizing our probability of technical success and financial resources.

During 2025, we made significant progress commercializing our product portfolio, developing and advancing our pipeline, and achieving our business goals, including the following:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Achieved full year net product revenue for ZORYVE® of $372.1 million, an increase of 123% over the prior year;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Produced positive cash flow beginning in the third quarter of 2025 with expectation to maintain positive operating cash flow on a quarterly basis going forward;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received FDA approval for, and launched in the United States, ZORYVE® (roflumilast) foam 0.3% for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received FDA approval for, and launched in the United States, ZORYVE® (roflumilast) cream 0.05% for the treatment of mild to moderate atopic dermatitis in children ages 2 to 5 years of age;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received Health Canada approval of ZORYVE® (roflumilast) cream 0.15% for the treatment of mild to moderate atopic dermatitis in adult and pediatric patients ages 6 years of age and older;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received Health Canada approval of ZORYVE® (roflumilast) foam 0.3% for the treatment of plaque psoriasis of the scalp and body in adults and pediatric patients ages 12 years of age and older;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Secured Medicare coverage such that 1 out of 3 Medicare lives are covered effective January 1, 2026;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Submitted sNDA for ZORYVE® (roflumilast) cream 0.3% to the FDA for the treatment of plaque psoriasis in children down to 2 years of age;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Completed enrollment for the INTEGUMENT-INFANT Phase 2 study of ZORYVE cream 0.05% in infants aged 3 months to less than 24 months with mild to moderate atopic dermatitis;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Initiated Phase 2 proof-of-concept studies with ZORYVE foam 0.3% for the treatment of vitiligo and hidradenitis suppurativa

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Submitted Investigational New Drug Application (IND) for ARQ-234, a novel fusion protein for the potential treatment of patients with atopic dermatitis;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Obtained multiple new U.S. patents for ZORYVE, and;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Received *Allure*'s "2025 Best Beauty Breakthrough Award", making it the first FDA-approved medication for atopic dermatitis, plaque psoriasis, and seborrheic dermatitis to win this prestigious award.

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**2025 Executive Compensation Program Highlights**

*Cash Compensation*

Historically, our compensation program has consisted of relatively modest cash compensation and has emphasized equity compensation consistent with common practices for other pre-IPO companies. Subsequent to our IPO in 2020, our compensation program continues to emphasize equity compensation, however, in 2025 we continued our multi-step process to better align the cash compensation for our named executive officers with competitive market practices of comparable public companies. For 2025, we increased the base salaries of our continuing named executive officers by approximately 3.1% to 8.7%. No increases were made in 2025 to the base salaries of our Chief Commercial Officer and Chief Medical Officer, both of whom received salary increases at the time of their promotions to Executive Vice President in December 2024. We did not increase the target bonus opportunity as a percentage of base salary for any of our named executive officers for 2025.

*Equity Awards*

Our continuing named executive officers received 2025 annual equity awards in a mix of stock options and restricted stock units (RSUs), at grant values that approximated the median of the 2025 peer group. We also awarded a promotional grant consisting of a mix of time-based options and RSUs to our Senior Vice President and Chief Financial Officer upon her promotion to this role in May 2025.

*Performance Results*

We had a strong year of execution across all departments and achieved our annual 2025 corporate goals at 125% of target.

**Executive Compensation Philosophy and Objectives**

Historically, our executive compensation program has been designed to motivate, reward, attract and retain high caliber management who create an inclusive and diverse environment and are deemed critical to our success. The program seeks to align executive compensation with our short-and long-term objectives, financial performance and stockholder priorities. Our compensation objectives are designed to support these goals by:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Attracting, retaining and motivating superior executive talent;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Providing fair and competitive compensation packages that are designed to incentivize executives to drive company performance;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Focusing on variable compensation that rewards the achievement of short-term and long-term goals and emphasizing our commitment to pay-for-performance; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Aligning our executives' interests with those of our stockholders to ensure that their compensation is meaningfully related to increasing shareholder value.

In keeping with our role as a publicly-held company, we maintain a commitment to strong corporate governance in connection with our named executive officer compensation arrangements where our Compensation Committee works with management to develop and maintain compensation frameworks that are appropriate and competitive for a public company. Our Compensation Committee works with Pay Governance, the Compensation Committee's compensation consultant, to formalize our compensation philosophy and implement compensation arrangements that reflect that philosophy.

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Our Compensation Committee reviews our executive compensation program to ensure our practices align the interests of our directors and executive officers with those of our stockholders. Below are features of our compensation program which the Compensation Committee believes demonstrate our commitment to link executive compensation to performance and to incentivize the creation of stockholder value.

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| | |
|:---|:---|
| **What We Do** | **What We Do Not Do** |
| ✔ Emphasize performance-based, at-risk compensation. | 🗷 Grant uncapped cash incentives or guaranteed equity compensation. |
| ✔ Emphasize the use of equity compensation to promote executive retention and reward long-term value creation. | 🗷 Guarantee executive officers annual salary increases or bonuses. |
| ✔ Weight the overall pay mix toward long-term incentive compensation for senior executives. | 🗷 Provide excessive perquisites. |
| ✔ Establish incentive compensation programs based on metrics that are aligned with our corporate strategy and designed to grow stockholder value. | 🗷 Provide any compensation-related tax gross-ups. |
| ✔ Structure change in control severance payments as "double-trigger", requiring both a change in control and an involuntary termination for payout. |  |
| ✔ Maintain an Insider Trading Compliance Policy that prohibits employees, officers and directors from engaging in pledging or hedging transactions. | |
| ✔ Maintain a Clawback Policy that allows the Company to seek to recover certain incentive compensation paid to its officers in situations where "Recoverable Events" have taken place. | |
| ✔ Maintain a Stock Ownership Policy to align the long-term interests of senior executives and non-employee directors with those of the Company's shareholders. | |
| ✔ Maintain a Compensation Committee comprised entirely of independent directors. | |
| ✔ Engage an independent compensation consultant to advise our Compensation Committee. | |
| ✔ Hold an annual say on pay stockholder advisory vote. | |
| ✔ Conduct annual pay equity assessments. | |

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**How We Determine Executive Compensation**

***Role of the Compensation Committee, Board of Directors, and Executive Officers***

The Compensation Committee oversees and recommends to the Board of Directors approval of all compensation arrangements for our executive officers, including our named executive officers. The

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Compensation Committee meets throughout the year to discuss and review our executive compensation program, and typically makes decisions on base salary, annual bonus, and equity awards for our continuing named executive officers in the first quarter of the year. As further described below, the Compensation Committee considers market data and input from its independent compensation consultant, Pay Governance, and other advisors in reviewing the competitiveness of individual compensation packages relative to peer company data and other relevant factors, including the performance and contributions of each named executive officer, our corporate performance and each individual's responsibilities, experience, and criticality to our business strategy.

For our 2025 compensation program, our Chief Executive Officer provided an assessment of these factors and made recommendations to the Compensation Committee to assist in determining fiscal 2025 compensation levels for the named executive officers other than himself. While the Compensation Committee and Board of Directors utilized this information, the ultimate decisions regarding fiscal 2025 executive compensation were made by the Compensation Committee and Board of Directors in their own independent judgment. With respect to our Chief Executive Officer's performance, the Compensation Committee considers input from the other independent members of the Board.

Our Compensation Committee regularly meets in executive session without management. While various members of management may attend committee meetings, none of our named executive officers participate in discussions or determinations regarding their own compensation.

***Role of Compensation Consultant***

The Compensation Committee has retained the services of Pay Governance as its independent compensation consultant. Pay Governance assists the Compensation Committee in its review of executive and director compensation practices, including the market competitiveness of compensation, executive compensation design, pay practices of industry peers, and other technical considerations including those related to tax and accounting.

For fiscal 2025, Pay Governance advised and assisted with the following:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Providing fair and competitive compensation packages that are designed to incentivize executives to drive company performance;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Development of a peer group to be used in the evaluation of 2025 executive and director compensation;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Market analysis of executive officer compensation compared to our peer group;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Market analysis of long-term incentive compensation of our executive officers compared to our peer group; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Market analysis of director compensation compared to our peer group.

The Compensation Committee regularly evaluates the services Pay Governance provides and has final authority to engage and terminate their services. Our Compensation Committee has assessed Pay Governance's independence consistent with Nasdaq listing standards and has concluded that the engagement of Pay Governance does not raise any conflict of interest.

***Competitive Assessment***

A key objective of our executive compensation program is to ensure that the overall compensation packages we offer our executive officers remain competitive with the packages offered by companies with which we compete for executive talent. The Compensation Committee consults with Pay Governance to develop a peer group of companies to serve as a reference when establishing and modifying executive compensation.

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***2025 Peer Group***

With the assistance of Pay Governance, the Compensation Committee annually reviews the composition of the peer group to account for changes in both our business and the businesses of the companies in the peer group. While referencing peer group compensation levels is helpful in determining market-competitive compensation for our named executive officers, the Compensation Committee and Board of Directors do not directly tie any pay elements to particular benchmarks within the peer group. Rather, peer data is one consideration, along with employee knowledge, skills, experience, individual performance, and scope of responsibilities, among other factors.

In developing the 2025 peer group, the Compensation Committee considered several qualitative and quantitative elements. The targeted criteria set out below were guidelines, and not all companies selected met each of the selection criteria.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Industry** – biotechnology/biopharmaceutical companies, with preference for companies with dermatology-related products;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**• Market Capitalization** – companies within a market capitalization range of $360 million to $3.25 billion (~1/3 to 3x our valuation at the time the peer group was developed) and that will position Arcutis closer to the median market capitalization value of our peer group;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Revenue** – companies with current and/or expected revenue for 2025 that is comparable to Arcutis' expected 2025 revenue;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Stage of Development** – primarily commercial companies and, to a lesser extent, later stage (Phase 3), pre-commercial companies;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Location** – strike a balance between companies with Southern and Northern California locations (with other U.S. geographies included as needed); and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• **Headcount** – companies with comparable headcount to Arcutis.

Following this analysis, the Compensation Committee identified the following 17 publicly-traded, U.S.-based biotechnology/biopharmaceutical companies as our peer group to be used in reviewing executive compensation for 2025:

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| | | |
|:---|:---|:---|
| **2025 Peer Group** | | |
| Agios Pharmaceuticals | AnaptysBio | Ardelyx |
| BioCryst Pharmaceuticals | Dynavax Technologies | Evolus |
| MannKind Corporation | Mirum Pharmaceuticals | Ocular Therapeutics |
| Phathom Pharmaceuticals | Protagonist Therapeutics | Sage Therapeutics |
| Tarsus Pharmaceuticals | Travere Therapeutics | Vanda Pharmaceuticals |
| Vericel | Y-mAbs Therapeutics |  |

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Bluebird Bio, Cara Therapeutics, Coherus Oncology, and Seres Therapeutics were removed from our peer group for 2025 because their market capitalizations were no longer in our targeted range. At the time the peer group was reviewed, their valuations were significantly lower than Arcutis's valuation. Alector was removed from our peer group for 2025 because their clinical program was in an earlier stage of development. In lieu of these companies that were removed, we added Ardelyx, Dynavax Technologies, Evolus, Mirum Pharmaceuticals, Ocular Therapeutics, Phathom Pharmaceuticals, and Vericel to our 2025 peer group.

Our Compensation Committee expects to periodically review and update this peer group and to utilize Pay Governance for peer group analysis in determining and developing compensation packages for our named executive officers.

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**Elements of Executive Compensation**

Historically, and for fiscal 2025, our executive compensation program consisted of the following elements, each established as part of our program in order to achieve the compensation objective specified below:

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| | |
|:---|:---|
| **Compensation Element** | **Compensation Objectives Designed to be Achieved<br>and Key Features** |
| Base Salary | Attract and retain key talent by providing base cash compensation at competitive levels. |
| Cash-Based Annual Incentive Compensation | Motivate and reward attainment of rigorous annual corporate performance goals identified as strategic drivers of long-term value creation. |
| Equity-Based Incentive Compensation | Provide long-term incentives in the form of equity-based compensation to drive an ownership mentality, encourage retention, provide strong alignment with shareholders and reinforce the importance long-term shareholder value creation. |
| Severance and Other Benefits Potentially Payable upon Termination of Employment or Change in Control | Create clarity around termination or change of control events and provide for retention of executives. |
| Health and Welfare Benefits | Attract and retain key talent by providing a competitive benefits package. |

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Our Compensation Committee has not established formal policies or guidelines for allocating compensation between annual and long-term incentive compensation, or between cash and non-cash compensation. Instead, through our compensation program, the Compensation Committee seeks to align pay and performance.

As can be seen in the graphs below, a large percentage of executive pay in 2025 was variable and "at-risk" (90% for the Chief Executive Officer, and 80% on average for our other named executive officers), meaning that value to the executive is tied directly to corporate goals and stock price performance. In this sense, we believe we have established a pay-for-performance culture and pay program. The balance between these components may change from year to year based on corporate strategy and objectives, among other considerations.

![16222](arqt-20260421_g1.jpg)

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![16224](arqt-20260421_g2.jpg)

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) Compensation for Mr. Topper has been excluded from the pay mix chart and related averages due to his departure during the year and the resulting atypical compensation structure, including prorated salary, severance, and no bonus payment which are not representative of ongoing executive compensation.

The equity awards granted to the other NEOs who were employed by the Company for the entirety of 2025, including the CEO, were comprised of a mix of RSUs and options.

**Base Salaries**

The base salaries of our named executive officers are a modest, but important part of their total compensation package, and are intended to reflect their respective positions, duties and responsibilities. Base salary is a visible and stable fixed component of our compensation program. Base salaries for our named executive officers were initially established by the Compensation Committee and/or Board of Directors at the time each executive was hired or promoted into their position.

In reviewing and adjusting base salaries for 2025, the Compensation Committee considered current market data as well as each named executive officer's total cash compensation (consisting of base salary and target bonus opportunity) and individual performance.

The following table sets forth the base salaries of our named executive officers for fiscal 2025:

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| | | | |
|:---|:---|:---|:---|
| **Named Executive Officer** | **Ending 2024 Base Salary** | **Ending 2025 Base Salary** | **% Increase** |
| Todd Franklin Watanabe (1) | $665000 | $723000 | 8.7% |
| Latha Vairavan (2) | $345000 | $450000 | 30.4% |
| Patrick Burnett, M.D., Ph.D. (3) | $535000 | $535000 | —% |
| L. Todd Edwards (3) | $535000 | $535000 | —% |
| Masaru Matsuda, J.D. (1) | $471000 | $500000 | 6.2% |
| David Topper (4) | $515000 | $531000 | 3.1% |

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&nbsp;&nbsp;&nbsp;&nbsp;(1)Salary increases for Mr. Watanabe and Mr. Matsuda went into effect on March 1, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;(2)Ms. Vairavan was promoted to Senior Vice President, Chief Financial Officer on May 6, 2025, and prior to such time served as our Vice President, Finance and Corporate Controller. Her ending base salary in 2025 includes a merit increase that went into effect on March 1, 2025 and a promotional increase that took effect upon her promotion.

&nbsp;&nbsp;&nbsp;&nbsp;(3)Mr. Burnett and Mr. Edwards did not receive salary increases in 2025, as their salaries were increased in December 2024 upon their promotions to Executive Vice President.

&nbsp;&nbsp;&nbsp;&nbsp;(4)Mr. Topper retired from the Company in May 2025.

**Cash-Based Incentive Compensation**

The Company maintains a cash annual incentive compensation program, whereby our named executive officers are eligible to receive cash incentive bonuses payable upon the achievement of specified annual corporate performance goals.

***Annual Corporate Performance Goals***

The Compensation Committee works with the executive team to develop goals with respect to the Company's annual incentive compensation program and ultimately recommends a list of goals to the Board for approval. The Board reviews the strategic, operational and financial components of the goals and approves the goals as well as a weighting for each goal based on its relative importance. Our Chief Executive Officer and executive team provide updates to the Board throughout the course of the year on performance towards these goals. At the end of the year, our Chief Executive Officer presents the Compensation Committee with a proposed score based on the Company's performance against the goals. After discussion and review, the Compensation Committee recommends to the Board for approval the overall corporate achievement score compared to the annual performance goals. This score is then used to establish the annual bonus payments for each named executive officer.

***Annual Bonus Process***

The Compensation Committee considers input from the Chief Executive Officer when reviewing the annual performance and compensation reviews for our executive officers and considers input from the non-employee members of our Board relative to the performance and compensation of our Chief Executive Officer. The Compensation Committee reviews base salary, annual bonus and equity-based compensation annually as part of this review. The review is typically conducted over a series of meetings beginning at the end of the year and as part of the Company's broader annual performance review process. The annual corporate score which is determined as described above in "Annual Corporate Performance Goals" is used to determine the size of the Company-wide bonus pool. Our Chief Executive Officer and named executive officers receive a bonus based entirely on corporate performance since they have ultimate operational responsibility for corporate performance. The Compensation Committee retains flexibility to increase or decrease any and all compensation components to reflect performance.

***2025 Bonus Targets***

We consider annual cash incentive bonuses to be an important component of our total compensation program that provide incentives necessary to retain executive officers. Each named executive officer is eligible to receive an annual performance-based cash bonus based on a specified target annual bonus award amount, expressed as a percentage of the named executive officer's base salary. Bonus targets are reviewed annually by the Compensation Committee, taking into consideration competitive market data, internal parity, promotions and other factors, and adjusted if deemed appropriate

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by the Compensation Committee. For fiscal 2025, our named executive officers participated in our annual cash incentive bonus program at the following target percentages of base salary:

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| | | |
|:---|:---|:---|
| **Named Executive Officer** | **2024 Bonus Target** | **2025 Bonus Target** |
| Todd Franklin Watanabe | 65% | 65% |
| Latha Vairavan (1) | 30% | 45% |
| Patrick Burnett, M.D., Ph.D.  | 50% | 50% |
| L. Todd Edwards  | 50% | 50% |
| Masaru Matsuda, J.D.  | 45% | 45% |
| David Topper (2) | 45% | 45% |

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&nbsp;&nbsp;&nbsp;&nbsp;(1)Ms. Vairavan was promoted to Senior Vice President, Chief Financial Officer on May 6, 2025, and prior to such time served as our Vice President, Finance and Corporate Controller. As part of Ms.Vairavan's promotion to Senior Vice President, Chief Financial Officer, the bonus target for Ms. Vairavan increased from 30% to 45%, effective May 1, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;(2)Mr. Topper did not receive a cash incentive bonus due to his retirement in May 2025.

***2025 Corporate Goal Development and Weighting***

We provide our executive officers the opportunity to receive annual cash incentives that are intended to encourage the achievement of corporate performance objectives. In January 2025, the Compensation Committee set the performance objectives for fiscal 2025, which mainly fell into seven categories: (i) Net Product Revenue for ZORYVE, (ii) ZORYVE Commercialization, (iii) Follow-On Indications, (iv) Advance the Pipeline, (v) Collaborations, (vi) Finance and (vii) Corporate. Our Corporate Bonus Plan provides the opportunity to achieve the maximum potential bonus of 150% overall if pre-specified stretch objectives are achieved. The charts below summarize our performance objectives, weightings and attainment under our Corporate Bonus Plan for fiscal 2025.

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Corporate Goals and Objectives:

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| | | |
|:---|:---|:---|
| **Goal Area and Target Weight** | **Objective** | **Results Achieved** |
| Zoryve Revenue<br>(40%) | • Achieve Arcutis Zoryve net product revenue goal with compliance excellence | 60% |
| Zoryve Commercialization<br>(20%) | • Scalp plaque psoriasis (PsO) launch in U.S.<br>• Pediatrics atopic dermatitis launch in U.S.<br>• Covered commercial scripts across all Zoryve approved indications<br>• Medicare Part D coverage<br>• Atopic dermatitis launch in Canada | 20% |
| Follow-On Indications<br>(10%) | • Scalp PsO SNDS approval in Canada<br>• ARQ-151-218 study initiation for atopic dermatitis study in 3-24 month olds<br>• Submit sNDA in the U.S. for PsO 0.3% cream for 2-5 year olds<br>• Submit atopic dermatitis SNDS in Canada for atopic dermatitis 0.05% cream | 15% |
| Advance the Pipeline<br>(5%) | • Submit ARQ-234 IND in the U.S.<br>• Complete ARQ-255 phase 1 study | 5% |
| Collaborations<br>(5%) | • Ensure clinical Huadong and Sato supply per development plans | 5% |
| Finance<br>(10%) | • Manage operating expenses<br>• Successfully transition to large company accelerated filer status<br>• Identify opportunities for meaningful outside expense savings | 10% |
| Corporate<br>(10%) | • Maintain cybersecurity maturity at 3.5/5<br>• Complete career development plans for all employees in executive succession plan<br>• Manage full-year voluntary turnover rate | 10% |
| **Total Goals Score:** | **Total Goals Score:** | **125%** |

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**Net Product Revenue for ZORYVE® (roflumilast)**

As a result of the focus of our executives and efforts of our talented colleagues throughout the Company, our performance exceeded consensus expectations. Full year 2025 net product revenue for ZORYVE was $372.1 million, an increase of 123% over the prior year, which was one of the primary drivers of achieving 125% on our corporate goals. Our culture of owning compliance continued to permeate the organization.

**ZORYVE Commercialization**

Product Coverage

We were able to achieve commercial covered scripts targets in plaque psoriasis, seborrheic dermatitis and atopic dermatitis. Overall ZORYVE commercial coverage was obtained in approximately 4 out of 5 patients. We were also able to secure coverage for over 50% of Medicare lives.

ZORYVE Expansion

In 2025, we launched ZORYVE foam 0.3% in the U.S. for the treatment of scalp and body psoriasis in adults and adolescents ages 12 and older and ZORYVE cream 0.05% for mild to moderate

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atopic dermatitis patients ages 2 to 5 years old. We also launched ZORYVE cream 0.15% in Canada for mild to moderate atopic dermatitis for patients as young as six years of age.

**Follow-on Indications**

We submitted a supplemental New Drug Application (sNDA) with the FDA for ZORYVE cream 0.3% for psoriasis in children ages 2 to 5 years, with a target action date of June 29, 2026. Additionally, during the year, we completed enrollment in our Phase 2 study (INTEGUMENT-INFANT) of ZORYVE cream 0.05% in infants with atopic dermatitis ages 3 to 24 months, then in February 2026, we presented positive topline data from that study.

In Canada, we received our approval in November 2025 for our supplement to New Drug Submission (SNDS) for Zoryve Foam 0.3% for scalp and body psoriasis in patients ages 12 and above. Additionally, we also submitted our SNDS for ZORYVE cream 0.05% for mild to moderate atopic dermatitis in children aged 2 to 5.

Lastly, in Q4 2025, we initiated two Phase 2 proof-of-concept (PoC) studies with ZORYVE foam 0.3% for the treatment of vitiligo and hidradenitis suppurativa. We anticipate starting additional PoC studies in the future.

**Advance the Pipeline**

We advanced our ARQ-234 drug candidate, a fusion protein that is a highly selective and potent checkpoint agonist, for the treatment of atopic dermatitis. We submitted an Investigational New Drug Application (IND) for ARQ-234 in July 2025, and are currently enrolling patients in our Phase 1 study.

Following the evaluation of results from the Phase 1b trial of ARQ-255, a penetrating topical formulation of ivarmacitinib for the treatment of alopecia areata, the Company elected to halt further development of this program. While clinical and biomarker results indicated some level of efficacy, the results did not meet the Company's threshold for advancement.

**Collaborations**

Our supply team worked to successfully supply all ZORYVE clinical product required to move the development plans forward for each of our ex-US strategic partners, Sato Pharmaceutical Co., Ltd. in Japan and Hangzhou Zhongmei Huadong Pharmaceutical Co. (Huadong) in Greater China and Southeast Asia.

**Finance** 

Management of Operating Expenses

Through rigorous financial planning and reporting processes, we were able to identify opportunities for meaningful outside expense savings, responsibly redeploy them to grow the business, and ultimately maintain our expenditures at or below the budget and priorities set by our Board.

Transition Back to Large Company Accelerated Filer Status

After our successful 2024 revenue results and public float, we earned our transition back to Large Company Accelerated Filer status in 2025 and successfully met the heightened reporting requirements and provision of the auditor attestation on our reported financials.

**Corporate**

Cybersecurity Maturity

Cybersecurity continues to emerge as a growing risk on a day-to-day basis. Our cybersecurity program promotes a structure and proactive process by which we identify, analyze and protect or mitigate

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threats to our information and systems that house it, and assesses our cybersecurity maturity level utilizing the NIST framework. In doing so, we continue to maintain at least a 3.5/5.0 score in an ever evolving and complex risk area.

Full-year Voluntary Turnover Rate

The talent of our colleagues is the most valuable asset we have at Arcutis. We would not be able to serve patients in the manner we have without the passion, talent, efforts and commitment of our colleagues. In order to bolster our retention, we invest in individual career development planning, leadership development programs, as well as award programs which recognize colleagues who exemplify the values that are the foundation of our Company culture. We are proud to report that our voluntary turnover rate for 2025 was below our internal target which was below the industry average.

***Evaluation of Performance Against 2025 Corporate Goals***

In January 2026, the Board evaluated the Company's performance against the above goals and determined that the Company had achieved corporate goals for fiscal 2025 at 125% of target levels.

In consideration of the foregoing, in February 2026, pursuant to the terms and conditions of the applicable annual bonus guidelines, the Board approved annual cash bonus payments for each named executive officer as reflected in the table below:

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| | | | | |
|:---|:---|:---|:---|:---|
| **Named Executive Officer** | **2025**<br>**Bonus Target** | **Corporate Goal<br>Score Modifier** | **2025 Actual Bonus**<br>**Paid as % of Salary** | **2025 Actual**<br>**Bonus Paid (1)** |
| Todd Franklin Watanabe (1) | 65% | 125% | 81% | $579584 |
| Latha Vairavan (2) | 45% | 125% | 51% | $213402 |
| Patrick Burnett, M.D., Ph.D. (1) | 50% | 125% | 63% | $334376 |
| L. Todd Edwards (1) | 50% | 125% | 63% | $334376 |
| Masaru Matsuda, J.D. (1) | 45% | 125% | 56% | $278532 |
| David Topper (3) | 45% | —% | —% | $— |

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(1)2025 bonuses were paid in March 2026. Bonuses paid to Mr. Watanabe, Mr. Burnett, Mr. Matsuda, and Mr. Edwards were calculated by multiplying their actual base salary earned in 2025 by their 2025 bonus target, and multiplying the resulting value by the corporate goal score modifier.

(2)As part of Ms.Vairavan's promotion to Senior Vice President, Chief Financial Officer, the bonus target for Ms. Vairavan increased from 30% to 45%, effective May 1, 2025. The pro-rated bonus paid to Ms. Vairavan was calculated by adding the two following values: i) her actual base salary earned from January 1 through April 30, 2025 multiplied by her bonus target of 30% multiplied by the corporate goal score modifier; and ii) her actual base salary earned from May 1, 2025 through December 31, 2025 multiplied by her new bonus target of 45% multiplied by the corporate goal score modifier.

(3)Mr. Topper did not receive a cash incentive bonus in 2025 due to his retirement in May 2025.

**2026 Annual Incentive Compensation Program** 

In February 2026, the Board also approved an annual incentive compensation program for 2026 for our NEOs on substantially similar terms and conditions as our 2025 annual incentive compensation program described above.

**Equity-Based Incentive Compensation**

We view equity-based compensation as a critical component of our balanced total compensation program. Equity-based compensation creates an ownership culture among our employees that provides an incentive to contribute to the continued growth and development of our business and aligns the interests of executives with those of our stockholders. In evaluating the mix of equity awards for 2025, the Compensation Committee considered market trends as well as practices of our peer group companies, and determined that a mix of stock options, restricted stock units and where appropriate, performance-based restricted stock units, would be the most appropriate incentive structure for our named executive officers to reward performance over time and achieve our retention objectives. We do

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not currently have any formal policy for determining the number of equity-based awards to grant to named executive officers.

***Stock Options***

The Compensation Committee and Board grant stock options to emphasize retention and align the named executive officers' interests with those of stockholders. These awards provide a necessary balance between performance-based and time-vesting awards. Stock option awards will generally be fully vested four years after the option grant date, subject to continuous service.

***Restricted Stock Units***

Restricted stock units (RSUs) are an important retention vehicle for named executive officers, as well as a variable and at-risk component of executive compensation. Market trends reflect their favored use among our peer group and other companies in the biotechnology sector. RSUs will generally be fully vested four years after the RSUs are granted, subject to continuous service.

***Performance-Based Equity***

In certain cases, the Compensation Committee and/or the Board grant performance-based stock options or performance-based restricted stock units (PSUs) that begin vesting upon the completion of specific performance criteria, with continued vesting subject to continuous service. Performance-based grants align the named executive officers' interests with those of stockholders by requiring the achievement of goals that the Compensation Committee expects to drive stock price growth.

In connection with Mr. Edwards commencing services as our Senior Vice President and Chief Commercial Officer in September 2023, our Compensation Committee and Board granted him 60,000 PSUs. The PSUs were to become earned based on the achievement of specified performance targets: (i) if Q1 2024 Zoryve total net sales forecast was achieved or exceeded, 30,000 PSUs would begin vesting; or (ii) if milestone 1 was not achieved and Q1 2024 total net sales forecast was achieved at 85% of forecast, 15,000 PSUs would begin vesting; and (iii) if Q1 2024 Zoryve Foam unit forecast was achieved or exceeded, 30,000 PSUs would begin vesting; or (iv) if milestone 3 was not achieved and Q1 2024 Zoryve Foam unit forecast was achieved at 85% of forecast, 15,000 PSUs would begin vesting. The first and third performance targets were achieved. Upon the date achievement of each respective performance target was certified by the Compensation Committee (the vesting commencement date), 30,000 PSUs vested, and the remaining 30,000 PSUs vested on the one-year anniversary of the vesting commencement date.

***2024 Option Exchange Offer***

In early 2024, we offered our employees and consultants, including our NEOs, the opportunity to exchange options with exercise prices in excess of $10.00 for a lesser number of new RSUs, subject to a new vesting schedule. We pursued this initiative as part of our continued efforts to retain top tier talent, and in recognition that our employees and consultants highly value equity incentive compensation. We view equity as a meaningful component of our balanced total compensation program which contributes to an ownership culture and strive to remain competitive in our compensation offerings to employees, including our NEOs. Non-employee directors were not eligible to participate.

The option exchange was offered at a crucial juncture for us when we most needed key talent continuity to execute on our then ongoing plaque psoriasis launch and our two commercial launches in 2024 in seborrheic dermatitis and atopic dermatitis. Our stock price had dropped from $20.74 per share of common stock on December 31, 2021 down to $3.23 on December 29, 2023. Given the drop in value our equity had suffered, our Compensation Committee determined that our equity-based compensation had little to no retentive effect. After losing a number of key talent in 2023, including executive officers, major investors advised that we needed to address retention in order to deliver on our strategy. We consider this to be a one-time event.

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The number of RSUs granted in exchange for options varied based on the exercise price of the options with participants receiving one RSU for between 2 and 3 shares of underlying options that were exchanged. Upon conclusion of the option exchange offer, there were 5,059,129 stock options exchanged for 2,129,594 RSUs.

In March 2025, our management held discussions with major investors who in the aggregate hold a majority of our outstanding shares of common stock and explained the purpose of the option exchange, its dilution friendly design and the fact that we consider this to be a one-time event. Such investors indicated their support of the option exchange, given our performance and execution on our strategy in 2024. Stockholder support for our fiscal 2024 compensation program was strong (approximately 84.68% support at our 2025 Annual Meeting of Stockholders).

***Equity Grants***

The following table sets forth the equity awards granted to our named executive officers in the 2025 fiscal year.

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| | | | | |
|:---|:---|:---|:---|:---|
| **Named Executive Officer** | **Grant Date** | **Type of Grant** | **Stock**<br>**Options (#)** | **RSUs (#)** |
| Todd Franklin Watanabe | 2/28/2025 | Annual | 396000 | 151000 |
| Latha Vairavan (1) | 2/28/2025 | Annual | 23750 | 11250 |
| Latha Vairavan (1) | 5/6/2025 | Promotion | 60000 | 20000 |
| Patrick Burnett, M.D., Ph.D. | 2/28/2025 | Annual | 99000 | 38000 |
| Patrick Burnett, M.D., Ph.D. (2) | 2/28/2025 | Promotion | 43000 | 17000 |
| L. Todd Edwards | 2/28/2025 | Annual | 99000 | 38000 |
| L. Todd Edwards (2) | 2/28/2025 | Promotion | 43000 | 17000 |
| Masaru Matsuda, J.D. | 2/28/2025 | Annual | 89000 | 34000 |
| David Topper (3) | 2/28/2025 | Annual | 89000 | 34000 |

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(1)Ms. Vairavan was promoted to Senior Vice President, Chief Financial Officer on May 6, 2025, and prior to such time served as Vice President, Finance and Corporate Controller. Her annual grant in 2025 was based on her level as a Vice President, and she received an additional equity grant upon her promotion in May 2025.

(2)Mr. Burnett and Mr. Edwards were promoted to Executive Vice President in December 2024. Equity grants associated with these promotions were made in 2025.

(3)Mr. Topper retired from the Company in May 2025, at which time his unvested stock options and RSUs were forfeited.

**Health, Welfare and Retirement Benefits**

Our employee benefit programs are designed to provide a competitive level of benefits to all of our full-time employees, including our named executive officers. All full-time employees are eligible to participate in our health and welfare plans, including:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Medical, dental, vision, and mental wellness benefits;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Medical and dependent care flexible spending accounts;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• 401(k) retirement savings plan, pursuant to which we make matching safe-harbor contributions under our 401(k) plan at 100% of the first 3% of each participant's contributions, plus 50% of each participant's next 2% of contributions, for a maximum aggregate matching contribution of 4%;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Long-term disability insurance; and

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Life insurance.

We believe the benefits described above are necessary and appropriate to provide a competitive compensation package to all of our full-time employees.

**Perquisites and Other Personal Benefits**

Currently, we do not view perquisites or other personal benefits as a significant component of our executive compensation program. Accordingly, we do not generally provide perquisites or other personal benefits to our executive officers, including our named executive officers, except as generally made available to our employees, or in situations where we believe it is appropriate to assist an individual in the performance of his or her duties, to make our executive officers more efficient and effective and for recruitment and retention purposes.

In the future, we may provide perquisites or other personal benefits in limited circumstances, such as those described in the preceding paragraph. All future practices with respect to perquisites or other personal benefits will be approved and subject to periodic review by the Compensation Committee.

**Employment and Severance Arrangements**

We have entered into employment agreements with all of our named executive officers, which provide for base salaries, target cash incentives, and benefit plan participation, as well as certain additional benefits as described below.

***Todd Franklin Watanabe***

We entered into a continued employment agreement with Mr. Watanabe, our President and Chief Executive Officer, in January 2020 (the "Watanabe Continued Employment Agreement"). The Watanabe Continued Employment Agreement outlined his initial base salary and target bonus opportunity, as well as the opportunity to continue participating in our employee benefit plans. In a November 2020 First Amendment to Continued Employment Letter, we amended the agreement to indicate that Mr. Watanabe's Principal Place of Employment is now in Utah and not California.

Under Mr. Watanabe's severance and change in control agreement (the "Watanabe Severance and Change in Control Agreement") that went into effect on the date of our initial public offering, he is entitled to certain benefits in the event of a termination of employment with cause, or resignation for good reason (both during and outside a change in control).

In the event of a qualifying termination outside of a change in control period, including resignation for good reason, Mr. Watanabe will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in the form of continuation of his base salary rate in effect immediately prior to the qualifying termination for twelve (12) months following termination; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Watanabe's timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) twelve (12) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Mr. Watanabe with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings.

In the event of a qualifying termination (i) within eighteen (18) months following a change in control or (ii) within three (3) months preceding a change in control, Mr. Watanabe will be entitled to receive the following benefits:

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in an amount equal to eighteen (18) months of his base salary rate in effect immediately prior to the qualifying termination plus 1.5 times his annual bonus amount for the then-current fiscal year based on 100% of target performance, paid out in substantially equal installments over an eighteen-month period;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Watanabe's timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) eighteen (18) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Mr. Watanabe with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full acceleration and immediate exercisability, if applicable, of all unvested equity awards subject to time-based vesting conditions.

The amounts set forth above are subject to Mr. Watanabe's timely delivery to us of a general release of claims that becomes effective and irrevocable.

***Latha Vairavan***

Ms. Vairavan first joined Arcutis as an Executive Director of Finance in March 2020, and was promoted to roles of increasing responsibility until she was lastly promoted to become our Senior Vice President and Chief Financial Officer, effective May 2025. Her base salary and target bonus opportunity are outlined above, and she has the opportunity to continue to participate in our employee benefit plans.

Under Ms. Vairavan's severance and change in control agreement (the "Vairavan Severance and Change in Control Agreement") that went into effect in May 2025, she is entitled to certain benefits in the event of a termination of employment with cause, or resignation for good reason (both during and outside a change in control).

In the event of a qualifying termination outside of a change in control period, including resignation for good reason, Ms. Vairavan will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in the form of continuation of her base salary rate in effect immediately prior to the qualifying termination for nine (9) months following termination; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Ms. Vairavan's timely election for continued coverage under COBRA, we shall pay, or reimburse, her monthly premium for her and her covered dependents under COBRA until the earliest of (a) nine (9) months, (b) the date when she receives similar coverage with a new employer, or (c) the expiration of her continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Ms. Vairavan with a monthly cash payment equal to the amount we would have otherwise paid for her monthly premium, less applicable tax withholdings.

In the event of a qualifying termination (i) within eighteen (18) months following a change in control or (ii) within three (3) months preceding a change in control, Ms. Vairavan will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in an amount equal to twelve (12) months of her base salary rate in effect immediately prior to the qualifying termination plus her annual bonus amount for the then-current

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fiscal year based on 100% of target performance, paid out in substantially equal installments over an twelve-month period;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Ms. Vairavan's timely election for continued coverage under COBRA, we shall pay, or reimburse, her monthly premium for her and her covered dependents under COBRA until the earliest of (a) twelve (12) months, (b) the date when she receives similar coverage with a new employer, or (c) the expiration of her continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Ms. Vairavan with a monthly cash payment equal to the amount we would have otherwise paid for her monthly premium, less applicable tax withholdings; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full acceleration and immediate exercisability, if applicable, of all unvested equity awards subject to time-based vesting conditions.

The amounts set forth above are subject to Ms. Vairavan's timely delivery to us of a general release of claims that becomes effective and irrevocable.

***Patrick Burnett, M.D., Ph.D.***

We entered into an executive employment agreement with Dr. Burnett, our Executive Vice President and Chief Medical Officer, in July 2020 (the "Burnett Employment Agreement") in connection with him joining us in August 2020. The Burnett Employment Agreement outlined his initial base salary and target bonus opportunity, as well as the opportunity to participate in our employee benefit plans. In addition, the Burnett Employment Agreement provides for reimbursement by us for travel expenses incurred for travel to and from, and housing, at our corporate headquarters, up to a maximum of $5,000 per month.

Under Dr. Burnett's severance and change in control agreement (the "Burnett Severance and Change in Control Agreement") that went into effect in July 2020, he is entitled to certain benefits in the event of a termination of employment with cause, or resignation for good reason (both during and outside a change in control).

In the event of a qualifying termination outside of a change in control period, including resignation for good reason, Dr. Burnett will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in the form of continuation of his base salary rate in effect immediately prior to the qualifying termination for nine (9) months following termination; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Dr. Burnett's timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) nine (9) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Dr. Burnett with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings.

In the event of a qualifying termination (i) within eighteen (18) months following a change in control or (ii) within three (3) months preceding a change in control, Dr. Burnett will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in an amount equal to twelve (12) months of his base salary rate in effect immediately prior to the qualifying termination plus his annual bonus amount for the then-current

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fiscal year based on 100% of target performance, paid out in substantially equal installments over an twelve-month period;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Dr. Burnett's timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) twelve (12) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Dr. Burnett with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full acceleration and immediate exercisability, if applicable, of all unvested equity awards subject to time-based vesting conditions, as well as the performance-based restricted stock units granted on August 3, 2020.

The amounts set forth above are subject to Dr. Burnett's timely delivery to us of a general release of claims that becomes effective and irrevocable.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;***L. Todd Edwards***

We entered into an executive employment agreement with Mr. Edwards, our Executive Vice President and Chief Commercial Officer, in September 2023 (the "Edwards Employment Agreement") in connection with him joining us in September 2023. The Edwards Employment Agreement outlined his initial base salary and target bonus opportunity, as well as the opportunity to participate in our employee benefit plans. In addition, the Edwards Employment Agreement provides for reimbursement by us for travel expenses incurred for travel to and from, and housing, at our corporate headquarters, in accordance with the Company's expense reimbursement policy, as in effect from time to time.

Under Mr. Edwards' severance and change in control agreement (the "Edwards Severance and Change in Control Agreement") that went into effect in September 2023, he is entitled to certain benefits in the event of a termination of employment with cause, or resignation for good reason (both during and outside a change in control).

In the event of a qualifying termination outside of a change in control period, including resignation for good reason, Mr. Edwards will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in the form of continuation of his base salary rate in effect immediately prior to the qualifying termination for nine (9) months following termination; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Edwards' timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) nine (9) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Mr. Edwards with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings.

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In the event of a qualifying termination (i) within eighteen (18) months following a change in control or (ii) within three (3) months preceding a change in control, Mr. Edwards will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in an amount equal to twelve (12) months of his base salary rate in effect immediately prior to the qualifying termination plus his annual bonus amount for the then-current fiscal year based on 100% of target performance, paid out in substantially equal installments over an twelve-month period;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Edwards' timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) twelve (12) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Mr. Edwards with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full acceleration and immediate exercisability, if applicable, of all unvested equity awards subject to time-based vesting conditions.

The amounts set forth above are subject to Mr. Edwards' timely delivery to us of a general release of claims that becomes effective and irrevocable.

***Masaru Matsuda, J.D.***

We entered into an executive employment agreement with Mr. Matsuda, our Executive Vice President and Chief Legal Officer, in December 2021 (the "Matsuda Employment Agreement") in connection with him joining us in January 2022. The Matsuda Employment Agreement outlined his initial base salary and target bonus opportunity, as well as the opportunity to participate in our employee benefit plans. In addition, the Matsuda Employment Agreement provides for reimbursement by us for travel expenses incurred for travel to and from, and housing, at our corporate headquarters, in accordance with the Company's expense reimbursement policy, as in effect from time to time.

Under Mr. Matsuda's severance and change in control agreement (the "Matsuda Severance and Change in Control Agreement") that went into effect in January 2022, he is entitled to certain benefits in the event of a termination of employment with cause, or resignation for good reason (both during and outside a change in control).

In the event of a qualifying termination outside of a change in control period, including resignation for good reason, Mr. Matsuda will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in the form of continuation of his base salary rate in effect immediately prior to the qualifying termination for nine (9) months following termination; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Matsuda's timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) nine (9) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Mr. Matsuda with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings.

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In the event of a qualifying termination (i) within eighteen (18) months following a change in control or (ii) within three (3) months preceding a change in control, Mr. Matsuda will be entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in an amount equal to twelve (12) months of his base salary rate in effect immediately prior to the qualifying termination plus his annual bonus amount for the then-current fiscal year based on 100% of target performance, paid out in substantially equal installments over an twelve-month period;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Matsuda's timely election for continued coverage under COBRA, we shall pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) twelve (12) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect that, in lieu of paying or reimbursing the premiums, we shall instead provide Mr. Matsuda with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full acceleration and immediate exercisability, if applicable, of all unvested equity awards subject to time-based vesting conditions.

The amounts set forth above are subject to Mr. Matsuda's timely delivery to us of a general release of claims that becomes effective and irrevocable.

***David Topper***

We entered into an executive employment agreement with Mr. Topper, our Senior Vice President and Chief Financial Officer, in April 2024 (the "Topper Employment Agreement") in connection with him joining us in April 2024. The Topper Employment Agreement outlined his initial base salary and target bonus opportunity, as well as the opportunity to participate in our employee benefit plans. In addition, the Topper Employment Agreement provides for reimbursement by us for travel expenses incurred for travel to and from, and housing, at our corporate headquarters, in accordance with the Company's expense reimbursement policy, as in effect from time to time.

Under Mr. Topper's severance and change in control agreement (the "Topper Severance and Change in Control Agreement") that went into effect in April 2024, he was entitled to certain benefits in the event of a termination of employment with cause, or resignation for good reason (both during and outside a change in control).

In the event of a qualifying termination outside of a change in control period, including resignation for good reason, Mr. Topper was entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in the form of continuation of his base salary rate in effect immediately prior to the qualifying termination for nine (9) months following termination; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Topper's timely election for continued coverage under COBRA, we would be required to pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) nine (9) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect, in lieu of paying or reimbursing the premiums, to provide Mr. Topper with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings.

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In the event of a qualifying termination (i) within eighteen (18) months following a change in control or (ii) within three (3) months preceding a change in control, Mr. Topper would have been entitled to receive the following benefits:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Severance pay in an amount equal to twelve (12) months of his base salary rate in effect immediately prior to the qualifying termination plus his annual bonus amount for the then-current fiscal year based on 100% of target performance, paid out in substantially equal installments over a twelve-month period;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Subject to Mr. Topper's timely election for continued coverage under COBRA, we would have been required to pay, or reimburse, his monthly premium for him and his covered dependents under COBRA until the earliest of (a) twelve (12) months, (b) the date when he receives similar coverage with a new employer, or (c) the expiration of his continuation coverage under COBRA. We may elect, in lieu of paying or reimbursing the premiums, to provide Mr. Topper with a monthly cash payment equal to the amount we would have otherwise paid for his monthly premium, less applicable tax withholdings; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Full acceleration and immediate exercisability, if applicable, of all unvested equity awards subject to time-based vesting conditions, as well as the performance-based restricted stock units granted on June 20, 2024.

The amounts set forth above would have been subject to Mr. Topper's timely delivery to us of a general release of claims that becomes effective and irrevocable.

On April 10, 2025, we announced that Mr. Topper would transition out of his role as Senior Vice President and Chief Financial Officer and retire, effective on the Transition Date. In connection with the transition, Mr. Topper continued to serve as our Senior Vice President and Chief Financial Officer until the Transition Date and provided transition support through his departure on May 15, 2025. In connection with the transition and Mr. Topper's timely execution and non-revocation of a general release, he received the benefits set forth above per the Topper Severance and Change of Control Agreement for a termination outside of a change in control period.

**Potential Payments Upon Termination or Change in Control**

The amount of compensation and benefits payable to each named executive officer in various termination and change in control situations has been estimated in the tables below. The value of the option and RSU vesting accelerations was calculated for each of the tables below on the assumption that the change in control and executive's employment termination occurred on December 31, 2025. The closing price of our common stock on December 31, 2025 was $29.04, which was used as the value of our common stock in the change in control calculations. The value of the option vesting acceleration was calculated by multiplying the number of unvested option shares subject to vesting acceleration as of December 31, 2025 by the difference between the closing price of our common stock as of December 31, 2025 and the exercise price. No value is attributed to unvested options subject to acceleration which have exercise prices above the closing market price of our common stock on December 31, 2025. The value of RSUs was calculated by multiplying the number of unvested RSUs subject to vesting acceleration as of December 31, 2025 by the closing price of our common stock on December 31, 2025. The respective severance and change in control agreement for each named executive officer includes a modified cutback provision, such that if any severance payments or benefits would constitute a "parachute payment" and would be subject to the excise tax imposed by Section 4999 of the Code, the aggregate benefits will either be delivered in full or delivered in a lesser amount that would result in no portion of the aggregate benefits being subject to the excise tax, whichever results in the receipt by the named executive officer of the greatest amount of aggregate benefits on an after-tax basis. For purposes of the table set forth below, it has been assumed that the payments and benefits will not be reduced

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pursuant to the preceding sentence and, accordingly, include the full value of such payments and benefits:

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| | | | | |
|:---|:---|:---|:---|:---|
| **Named Executive Officer** | **Termination by Company without Cause or resignation for Good Reason not in Change in Control Period ($)** | **Termination by Company without Cause or resignation for Good Reason during a Change in Control Period ($)** | **Termination by Company on Death or Disability ($)** | **Termination by Company for Cause or resignation without Good Reason ($)** |
| **Todd Franklin Watanabe**<br>*Base salary continuation (1)*<br>*Bonus continuation (1)*<br>*Lump sum bonus payment (2)*<br>*COBRA premiums (3)*<br>*Accelerated vesting of equity awards* | <br>723000<br>--<br>--<br>26666<br>-- | <br>1084500<br>704925<br>--<br>40000<br>21121830 | <br>--<br>--<br>--<br>--<br>-- | <br>--<br>--<br>--<br>--<br>-- |
| **Latha Vairavan**<br>*Base salary continuation (1)*<br>*Bonus continuation (1)*<br>*Lump sum bonus payment (2)*<br>*COBRA premiums (3)*<br>*Accelerated vesting of equity awards* | <br>337500<br>--<br>--<br>34226<br>-- | <br>450000<br>202500<br>--<br>45634<br>2997711 | <br>--<br>--<br>--<br>--<br>-- | <br>--<br>--<br>--<br>--<br>-- |
| **Patrick Burnett, M.D., Ph.D**.<br>*Base salary continuation (1)*<br>*Bonus continuation (1)*<br>*Lump sum bonus payment (2)*<br>*COBRA premiums (3)*<br>*Accelerated vesting of equity awards* | <br>401250<br>--<br>--<br>34226<br>-- | <br>535000<br>267500<br>--<br>45634<br>8642951 | <br>--<br>--<br>--<br>--<br>-- | <br>--<br>--<br>--<br>--<br>-- |
| **L. Todd Edwards**<br>*Base salary continuation (1)*<br>*Bonus continuation (1)*<br>*Lump sum bonus payment (2)*<br>*COBRA premiums (3)* <br>*Accelerated vesting of equity awards* | <br>401250<br>--<br>--<br>23901<br>-- | <br>535000<br>267500<br>--<br>31868<br>9758173 | <br>--<br>--<br>--<br>--<br>-- | <br>--<br>--<br>--<br>--<br>-- |
| **Masaru Matsuda, J.D.**<br>*Base salary continuation (1)*<br>*Bonus continuation (1)*<br>*Lump sum bonus payment (2)*<br>*COBRA premiums (3)*<br>*Accelerated vesting of equity awards* | <br>375000<br>--<br>--<br>34226<br>-- | <br>500000<br>225000<br>--<br>45634<br>6107281 | <br>--<br>--<br>--<br>--<br>-- | <br>--<br>--<br>--<br>--<br>-- |
| Total | $2391244 | $53608640 |  |  |

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(1)Reflects the aggregate amount of cash severance payable to each named executive officer based on a multiple of base salary and target annual incentive compensation as of 2025 pursuant to the terms of the respective named executive officer's severance and change in control agreement, as described above.

(2)Amounts reported in this table exclude accrued but unpaid annual incentive compensation, as such amounts relate to services previously performed and do not constitute payments triggered by, or contingent upon, a termination of employment or a change in control.

(3)Represents the estimated value of the continuation of health benefits that each named executive officer would have been entitled to receive upon a termination of employment as of December 31, 2025, as based on actual 2025 premiums and the terms of the respective named executive's officer's severance and change in control agreement, as described above.

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In connection with Mr. Topper's termination of employment and in exchange for a release of claims against us, Mr. Topper received 9 months of continued base salary in the aggregate amount of $398,250 and we paid COBRA premiums on his behalf in the aggregate amount of $21,521.

**Accounting and Tax Considerations**

As a general matter, the Compensation Committee and our Board of Directors review and consider the various tax and accounting implications of compensation programs we utilize.

***Deductibility of Executive Compensation***

Section 162(m) of the Internal Revenue Code ("Section 162(m)") generally disallows a federal income tax deduction for remuneration in excess of $1 million paid by a public corporation in a fiscal year to an officer that meets the definition of a "Covered Employee" as defined under Section 162(m). Covered Employees include our chief executive officer, chief financial officer, and any other employee who is among the three highest compensated employees for the taxable year (other than the chief executive officer and chief financial officer). The determination of which employees are deemed Covered Employees under Section 162(m) is made annually based on compensation paid during that taxable year, both in terms of how many employees are covered and which specific employees qualify. In addition, once an individual becomes a Covered Employee, that individual will remain a Covered Employee for all future years, including if they are no longer the highest compensated employees in subsequent years or whether their employment has terminated.

While we may take into account deductibility of compensation when making compensation decisions, our Compensation Committee believes that stockholder interests are best served if our Compensation Committee retains maximum flexibility to design executive compensation programs that meet stated business objectives. Therefore, our Compensation Committee has approved base salaries and other compensation awards for our executive officers that may not be fully deductible because of the deduction limit of Section 162(m) and expects in the future to approve additional compensation that is not deductible for federal income tax purposes.

***Accounting for Stock-Based Compensation***

We follow the Financial Accounting Standard Board's Accounting Standards Codification Topic 718 ("FASB ASC Topic 718") for our stock-based compensation awards. FASB ASC Topic 718 requires us to measure the compensation expense for all share-based payment awards made to our employees and non-employee members of our Board of Directors, including options to purchase shares of our common stock and other stock awards, based on the grant date "fair value" of these awards. This calculation is performed for accounting purposes and reported in the executive compensation tables required by the federal securities laws, even though the recipient of the awards may never realize any value from their awards.

**Other Compensation Policies and Practices**

***Clawback Policy***

Our Clawback Policy applies to incentive compensation paid to our senior executives, including our NEOs. The policy provides that if we are required to prepare an accounting restatement due to our material non-compliance with any financial reporting requirement, our Compensation Committee shall require the NEO to forfeit all or part of any applicable incentive compensation received by the NEO during the covered period. For purposes of this policy, incentive compensation means any compensation that is earned, granted, or vested based wholly or in part upon the attainment of a financial reporting measure. Our Clawback Policy complies with the requirements of Section 10D of the Exchange Act and Nasdaq rules. For more information, see our Policy for Recovery of Erroneously Awarded Compensation, which is filed as an exhibit to our 2025 Annual Report on Form 10-K.

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***Stock Ownership Policy***

Our Stock Ownership Policy encourages executive officers, including NEOs, and non-employee directors to remain invested in the performance of the Company and helps to align their long-term interests with those of the Company's shareholders by having a financial stake in the Company. In accordance with this policy, (i) each non-employee director must maintain beneficial ownership of a number of shares of our common stock with a value of at least three times his or her annual cash compensation for Board service (with the exception of committee service), (ii) the CEO must maintain beneficial ownership of a number of shares of our common stock with a value of at least three times his or her annual base salary, and (iii) each executive officer must maintain beneficial ownership of a number of shares of our common stock with a value of at least one times his or her annual base salary. For purposes of determining beneficial ownership, shares that count toward the satisfaction of the beneficial ownership requirements are set forth in the policy and include shares of common stock (a) held directly or indirectly or by or for the benefit of immediate family members, (b) by trusts for the benefit of such persons or such person's immediate family members, (c) in certain retirement, employee equity purchase or deferred compensation plans, (d) underlying restricted stock or restricted stock units awards that vest solely based on the passage of time (and for executive officers, net of shares that would need to be withheld for taxes), and (e) venture or other institutional investor funds under the control of such individual. Shares that do not count toward the satisfaction of the beneficial ownership requirements include shares of common stock (x) underlying outstanding stock options or performance-based options (whether vested or unvested), (y) unearned performance stock units or other incentive awards for which the performance milestone has not been achieved, and (z) warrants and all other forms of derivative securities. These beneficial ownership requirements must be met on the later of (i) on or before the 5th anniversary of the establishment of such policy (*i.e.*, June 27, 2027), (ii) for executive officers only, December 31 of the year in which the 5th anniversary of a person's appointment or election to the role making such person subject to the policy occurs or (iii) for newly appointed non-employee directors only, the date of the annual stockholders meeting in the year in which the 5th anniversary of such person's appointment to the Board occurs. While the compliance dates do not occur until June 2027, every person subject to the policy is either in compliance or is tracking to be well-within the allotted compliance date.

***Policies and Practices Related to the Timing of Equity Grants***

We generally grant annual equity-based awards to our executive officers in the first quarter of each calendar year during the performance review cycle, although the exact timing of the awards may change from year to year. The Compensation Committee or the Board of Directors may also grant equity awards, including stock options, at different times of the year to new hires and in connection with promotions or other job changes. Neither the Compensation Committee nor the Board of Directors grants equity awards in anticipation of the release of material non-public information and we have not timed the disclosure of material non-public information for the purpose of affecting the value of executive compensation.

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The following table contains information required by Item 402(x)(2) of Regulation S-K about stock options granted to our named executive officers in 2024 during the period beginning four business days before and ending one business day after (1) the filing of our Form 10-Q on May 6, 2025. The below stock options were granted to Latha Vairavan upon promotion to Chief Financial Officer:

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| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **Named Executive Officer** | **Grant Date** | **Number of Securities Underlying the Award** | **Exercise Price of the Award ($/Share)** | **Grant Date Fair Value of the Award ($)(1)** | **Percentage change in the closing market price of the securities underlying the award between the trading day ending immediately prior to the disclosure of material nonpublic information and the trading day beginning immediately following the disclosure of material nonpublic information** |
| Latha Vairavan | 5/6/2025 | 60000 | 14.32 | 608623 | (4.3)% |

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(1)Amounts represent grant date fair values of the Stock Options computed in accordance with ASC Topic 718. The aggregate grant date fair value for the Stock Options was based on the Black-Scholes option valuation methodology. For additional information, refer to Note 10 of the audited financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 for the assumptions used in calculating these amounts.

***Compensation Risk Assessment***

Consistent with the SEC's disclosure requirements, Pay Governance, our independent compensation consultant, assessed our compensation programs for all employees. We have concluded that our compensation policies and practices do not create risks that are reasonably likely to have a material adverse effect on us.

The Compensation Committee monitors our compensation programs on an annual basis and expects to make modifications as necessary to address any changes in our business or risk profile.

***Pay Equity Assessment***

In January 2026, we retained TalentAINow to conduct a pay equity assessment of our United States employees below the Senior Vice President level. The purpose of this assessment was to identify potential pay gaps by analyzing whether factors like race, ethnicity or gender affect employee pay, while simultaneously controlling for factors that could legitimately influence compensation, such as function, pay grade, manager versus individual contributor, performance, education, span of control, tenure in role, and experience. TalentAINow utilized regression models to conduct the assessment and found no evidence of a systemic pay equity issue across Arcutis.

**CEO Pay Ratio Disclosure**

Under the Dodd-Frank Act and the related SEC rules, we are required to provide our stockholders with specified disclosure regarding the relationship of our Chief Executive Officer's total compensation to the total compensation of our median employee, referred to as "pay-ratio" disclosure. For 2025, the annual total compensation of our Chief Executive Officer, for purposes of this disclosure, was $7,223,065, and the compensation of our median employee was $262,613, resulting in a pay ratio of approximately 28:1. The annual total compensation amounts for our Chief Executive Officer and our median employee include actual base salary earned in 2025, actual bonus earned in 2025 and paid in March 2026, the grant date fair value of the annual equity awards received in 2025, and other compensation received.

We identified a new median employee for 2025 due to changes in compensation levels during the year that we reasonably believed could materially affect the pay ratio disclosure, such that continued use of the previously identified median employee would not appropriately reflect our workforce for this calculation. In accordance with SEC rules, we have identified the median employee as of December 31, 2025 by: (i) aggregating for each applicable employee: (a) annual base salary rate for salaried employees (or annualized rate for hourly employees, excluding overtime), (b) the target incentive pay for fiscal year 2025, and (c) the 2025 target value of the annual equity awards, excluding new-hire awards, for fiscal

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year 2025, and (ii) ranking this compensation measure for our employees from lowest to highest. This calculation was performed for all employees employed by us as of December 31, 2025, excluding the Chief Executive Officer, whether employed on a full-time, part-time or seasonal basis. In making this determination, we annualized the compensation of employees who were employed by the Company for less than the entire fiscal year. This compensation measure was consistently applied to all employees included in the calculation and reasonably reflects the annual compensation of employees. All amounts paid in currencies other than US Dollars were converted to US Dollars based on the applicable average annual exchange rates.

The pay ratio reported above is a reasonable estimate calculated in a manner consistent with SEC rules based on our internal records and the methodology described above. The SEC rules for identifying the median compensated employee and calculating the pay ratio based on that employee's annual total compensation allow companies to adopt a variety of methodologies, to apply certain exclusions, and to make reasonable estimates and assumptions that reflect their employee populations and compensation practices. Therefore, the pay ratio reported by other companies may not be comparable to the pay ratio reported above, as other companies have different employee populations and compensation practices and may utilize different methodologies, exclusions, estimates and assumptions in calculating their own pay ratios.

**Pay Versus Performance Table** 

The following table sets forth information regarding the total compensation, for services rendered in all capacities, that was paid to, awarded to or earned by our CEO (referred to below as our "PEO" or principal executive officer) (and on average to our non-CEO NEOs, or our "Other NEOs"), as compared to compensation actually paid ("CAP") to our CEO (and on average to our Other NEOs) and certain Company and peer performance measures during the years ended December 31, 2025, 2024, 2023, 2022, and 2021, as calculated in accordance with Item 402(v) of Regulation S-K (the "Pay Versus Performance Table"):

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| | | | | | **Value of Initial Fixed $100 Investment Based on:** | **Value of Initial Fixed $100 Investment Based on:** | |
| **Year** |<br>**Summary Compensation Table Total for PEO ($)** |<br>**Compensation Actually Paid to PEO ($)(1)** |<br>**Average Summary Compensation Table Total for Other NEOs ($)** |<br>**Average Compensation Actually Paid to Other NEOs ($)(1)** | **Total Shareholder Return ($)(2)** | **Peer Group Total Shareholder Return ($)(3)** |<br>**Net Income ($)** |
| 2025 | 7223065 | 20353965 | 2407312 | 4865316 | 103.23 | 119.92 | (16141000) |
| 2024 | 3689490 | 11213466 | 2725870 | 5020816 | 49.52 | 90.58 | (140039000) |
| 2023 | 4935266 | (1156797) | 1622096 | 231716 | 11.48 | 91.84 | (262140000) |
| 2022 | 4581555 | 2422054 | 2310749 | 1326466 | 52.61 | 88.53 | (311458000) |
| 2021 | 4824123 | 441904 | 3070296 | 1021432 | 73.73 | 99.37 | (206356000) |

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(1)Amounts represent compensation actually paid to our CEO (which was Todd Franklin Watanabe each year) and the average compensation actually paid to our Other NEOs for the relevant fiscal year, as determined under SEC rules (and described below), which includes:

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| | |
|:---|:---|
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Year** | **Other NEOs** |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2025 | Latha Vairavan, Patrick Burnett, L. Todd Edwards, Masaru Matsuda, and David Topper<sup>(a.)</sup> |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2024 | David Topper, Patrick Burnett, L. Todd Edwards, Masaru Matsuda, and John Smither |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2023 | Patrick Burnett and L. Todd Edwards |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2022 | Masaru Matsuda, Patrick Burnett, Kenneth Lock, and Scott Burrows |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2021 | Matthew Moore, Scott Burrows, Patrick Burnett, David Osborne, and John Smither |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a.Mr. Topper retired from the Company in May 2025 and therefore his compensation included in the average NEO's may not be comparable to the other NEO's. He received prorated salary and severance payments, did not receive a 2025 bonus payment, and forfeited his outstanding equity awards, which are not representative of other NEO's compensation. See following "Executive Compensation Table".

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CAP to our NEOs represents the "Total" compensation reported in the Summary Compensation Table for the applicable fiscal year, as adjusted as follows:

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| | | |
|:---|:---|:---|
| | **2025** | **2025** |
| **Adjustments** | **PEO** | **Average Other NEOs** |
| **Deduction for Amounts Reported under the "Stock Awards" and "Option Awards" Columns in the Summary Compensation Table for Applicable FY** | $(5916148) | $(1641429) |
| **Increase based on ASC 718 Fair Value of Awards Granted during Applicable FY that Remain Unvested as of Applicable FY End, determined as of Applicable FY End** | $11348315 | $2634888 |
| **Increase based on ASC 718 Fair Value of Awards Granted during Applicable FY that Vested during Applicable FY, determined as of Vesting Date** | $868083 | $203256 |
| **Increase/deduction for Awards Granted during Prior FY that were Outstanding and Unvested as of Applicable FY End, determined based on change in ASC 718 Fair Value from Prior FY End to Applicable FY End** | $6326268 | $1821731 |
| **Increase/deduction for Awards Granted during Prior FY that Vested During Applicable FY, determined based on change in ASC 718 Fair Value from Prior FY End to Vesting Date** | $504382 | $191160 |
| **Deduction for Awards Granted during Applicable FY that were forfeited during Applicable FY, determined as of prior FY End (b.)** | $— | $(751602) |
| **TOTAL ADJUSTMENTS** | $13130900 | $2458004 |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;b.Forfeitures as a result of the departure of our prior CFO, David Topper.

(2)The column assumes $100 was invested for the period starting December 31, 2020 through the end of the listed year in the Company. Historical stock performance is not necessarily indicative of future stock performance.

(3)For the relevant fiscal year, represents the cumulative TSR (the "Peer Group TSR") of the Nasdaq Biotechnology Index (the "Peer Group"), which we also utilize in the stock performance graph required by Item 201(e) of Regulation S-K included in our Annual Report for the year ended December 31, 2025. The comparison assumes $100 was invested for the period starting December 31, 2020 through the end of the listed year in the Company and in the Peer Group, respectively. Historical stock performance is not necessarily indicative of future stock performance.

**Narrative Disclosure to Pay Versus Performance Table**

***Description of Between CEO and Other NEOs CAP and Financial Performance Measures***

The graphs below compare the CAP to our CEO and the average of the CAP to our Other NEOs, with (i) our cumulative TSR and (ii) our net income, in each case, for the fiscal years ended December 31, 2021, 2022, 2023, 2024 and 2025. CAP is influenced by numerous factors including, but not limited to, the timing of new grant issuances and award vesting, NEO mix, share price volatility during the fiscal year, our mix of performance metrics and other factors.

TSR amounts reported in the graph assume an initial fixed investment of $100 was invested for the period starting December 31, 2020 through the end of the listed year in the Company and our Peer Group.

Although Item 402(v) of Regulation S-K requires the description of the relationship between the compensation actually paid for our NEOs and our net income, we do not currently utilize GAAP or non-GAAP net income as a performance measure in any of our incentive programs. As a result, the impact of year-over-year fluctuations in our net income has less of an impact on compensation actually paid. The key factor that drove the changes in compensation actually paid is the fluctuation of our stock price.

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![Ch 1.jpg](arqt-20260421_g3.jpg)

![CH 2 .jpg](arqt-20260421_g4.jpg)

***Pay Versus Performance Tabular List***

In the years covered by this table, we did not use financial performance measures for our short or long-term incentive compensation for our NEOs. As described in more detail in "Executive Compensation – Compensation Discussion and Analysis," our executive compensation program reflects a variable "pay-for-performance" philosophy. Since our initial public offering in 2020, we have not used financial or other performance measures to align executive compensation with our performance. Therefore, this analysis only covers the performance measures presented in the Pay-Versus-Performance Table. Moreover, while we generally seek to prioritize long-term performance as our primary incentive for our CEO and our other NEOs, we do not specifically align our performance measures with compensation that is actually paid (as computed in accordance with Item 402(v) of Regulation S-K) for a particular year.

**Advisory Vote on Executive Compensation ("Say-on-Pay" vote)**

In 2022, we held a vote on the frequency of any future Say-on-Pay votes, which approved an annual non-binding advisory vote on the compensation of our named executive officers. In setting the form and amount of compensation for our named executive officers, the Compensation Committee considered the voting results from this non-binding advisory Say-On-Pay vote as well as feedback received from stockholders throughout the year. Stockholder support for our fiscal 2024 compensation program was strong (approximately 84.68% support at our 2025 Annual Meeting of Stockholders) and did not lead us to make any fundamental changes were to our executive compensation program. We will be conducting our next Say-on-Pay vote on the compensation of our named executive officers at this

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upcoming 2026 Annual Meeting of Stockholders as a result of our non-binding Say-on-Frequency vote from the 2022 Annual Meeting of the Stockholders. See the section titled "Proposal No. 3 Approval, on a Non-Binding, Advisory Basis, of the Compensation of our Named Executive Officers" for more information. We value the opinions of our stockholders and will consider the outcome of future Say-on-Pay votes, as well as any feedback received throughout the year, when making compensation decisions for our executive officers.

**Compensation Committee Report**

This report of the Compensation Committee shall not be deemed to be incorporated by reference into any filing made by Arcutis Biotherapeutics, Inc. under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, notwithstanding any general statement contained in any such filing incorporating this proxy statement by reference, except to the extent the Company incorporates such report by specific reference.

The Compensation Committee has reviewed and discussed the Compensation Discussion and Analysis with management. Based on this review and these discussions, we have recommended to the Board of Directors that the Compensation Discussion and Analysis be included in the Annual Report on Form 10-K and the proxy statement of Arcutis Biotherapeutics, Inc.

The preceding report has been furnished by the following members of the Compensation Committee:

Amit Munshi, Chair

Patrick Heron

Keith Leonard

**EXECUTIVE COMPENSATION TABLE**

**2025 Summary Compensation Table**

The following table sets forth information regarding the total compensation, for services rendered in all capacities, that was paid or awarded to or earned by our NEOs during the fiscal years ended December 31, 2025, 2024 and 2023:

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| **Name and Principal** <br>**Position** | **Year** | **Salary** <br>**($)** | **Stock Awards** <br>**($) (1)** | **Option Awards** <br>**($) (1)** | **Non-Equity** <br>**Incentive Plan** <br>**Compensation** <br>**($) (2)** | **All Other** <br>**Compensation** <br>**($) (3)** | **Total ($)** |
| Todd Franklin Watanabe | 2025 | 713333 | &nbsp;&nbsp;2067190 | 3848958 | 579584 | 14000 | 7223065 |
| &nbsp;&nbsp;*President and Chief* | 2024 | 660867 | &nbsp;&nbsp;1405630 | 1053227 | 549841 | 19926 | 3689491 |
| &nbsp;&nbsp;*Executive Officer* | 2023 | 633500 | &nbsp;&nbsp;1384250 | 2543320 | 354127 | 20069 | 4935266 |
| Latha Vairavan (4) | 2025 | 419485 | &nbsp;&nbsp;440413 | 839463 | 213402 | 12017 | 1924780 |
| &nbsp;&nbsp;*Chief Financial Officer* |  |  |  |  |  |  |  |
| Patrick E. Burnett, | 2025 | 535000 | &nbsp;&nbsp;752950 | 1380182 | 334376 | 14000 | 3016508 |
| &nbsp;&nbsp;M.D., Ph.D. | 2024 | 504203 | &nbsp;&nbsp;989282 | 709002 | 293274 | 17289 | 2513050 |
| &nbsp;&nbsp;*Chief Medical Officer* | 2023 | 477267 | &nbsp;&nbsp;332220 | 611185 | 230878 | 14795 | 1666345 |
| L. Todd Edwards  | 2025 | 535000 | &nbsp;&nbsp;752950 | 1380182 | 334376 | 27829 | 3030337 |
| &nbsp;&nbsp;*Chief Commercial Officer* | 2024 | 516419 | &nbsp;&nbsp;679120 | 452117 | 300311 | 17178 | 1965145 |
| Masaru Matsuda, J.D.  | 2025 | 495167 | &nbsp;&nbsp;465460 | 865044 | 278532 | 14000 | 2118203 |
| &nbsp;&nbsp;*Chief Legal Officer* | 2024 | 465472 | &nbsp;&nbsp;535475 | 452117 | 268112 | 16356 | 1737532 |
|  | 2023 | 434027 | &nbsp;&nbsp;332220 | 611185 | 209961 | 15756 | 1603149 |
| David Topper (5) | 2025 | 196458 | &nbsp;&nbsp;465460 | 865044 |  | 419771 | 1946733 |
| &nbsp;&nbsp;*Former Chief Financial Officer* | 2024 | 364792 | &nbsp;&nbsp;1854200 | 2772155 | 296640 | 23416 | 5311203 |

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(1)Amounts reflect the full grant date fair value of stock and option awards computed in accordance with ASC Topic 718 during the year ended December 31, 2025. See Note 10 of the audited financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 for the assumptions used in calculating these amounts. These amounts do not correspond to the actual value that may be recognized by the NEOs upon vesting of the applicable awards.

(2)Amounts represent the annual performance-based cash incentive earned by our NEOs based on the achievement of certain corporate performance objectives and individual performance during 2025. These amounts were paid to the NEOs in March 2026. See the descriptions of the annual performance incentive payments paid to our NEOs under "Cash-Based Incentive Compensation" above.

(3)Amount represents our matching contributions under our 401(k) plan and reimbursements for travel and housing related to travel to Corporate headquarters. 401(k) matching contributions were $14,000 for Mr. Watanabe, $12,017 for Ms. Vairavan, $14,000 for Mr. Burnett, $14,000 for Mr. Edwards, and $14,000 for Mr. Matsuda. Travel and housing reimbursements related to travel to Corporate headquarters were $13,829 for Mr. Edwards.

(4)Ms. Vairavan commenced her employment with us in March 2020 and was promoted to Chief Financial Officer on May 6, 2025.

(5)Mr Topper commenced his employment with us in April 2024. Mr. Topper separated from the Company effective May 15, 2025. The amount reported as salary for Mr. Topper in 2025 represents the total salary earned by Mr. Topper during 2025 prior to his separation. Under the terms of Mr. Topper's separation agreement, Mr. Topper was paid the following severance pay and benefits: (i) nine months of pay at his annual base salary rate in effect immediately prior to the separation date, less applicable taxes and withholdings and (ii) nine months of COBRA continuation. Mr. Toppers 'all other compensation' includes severance payments in the amount of $398,250 and payments paid or accrued for the continuation of health insurance for $21,521. He was not eligible for and therefore not paid an annual performance-based cash incentive for 2025.

**Grants of Plan-Based Awards Table**

The following table provides information about the plan-based awards granted in 2025 to each of our NEOs:

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| | | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | | | **Estimated Future Payouts Under Non-Equity Incentive Plan Awards ($)(1)** | **Estimated Future Payouts Under Non-Equity Incentive Plan Awards ($)(1)** | **Estimated Future Payouts Under Equity Incentive Plan Awards (#)** | **Estimated Future Payouts Under Equity Incentive Plan Awards (#)** | **All Other<br>Stock<br>Awards:<br>Number of<br>Shares of<br>Stock or<br>Units** | **All Other<br>Option<br>Awards:<br>Number of<br>Securities<br>Underlying<br>Options** | **Exercise or<br>Base Price<br>of<br>Awards** | **Grant Date**<br>**Fair Value**<br>**of Stock**<br>**Options**<br>**and Awards ($) (2)** |
| | **Grant Date** | | **Target** | **Maximum** | **Target** | **Maximum** | **All Other<br>Stock<br>Awards:<br>Number of<br>Shares of<br>Stock or<br>Units** | **All Other<br>Option<br>Awards:<br>Number of<br>Securities<br>Underlying<br>Options** | **Exercise or<br>Base Price<br>of<br>Awards** | **Grant Date**<br>**Fair Value**<br>**of Stock**<br>**Options**<br>**and Awards ($) (2)** |
| **NEO** | **Grant Date** |  | &nbsp;&nbsp;*Cash bonus* | &nbsp;&nbsp;*Cash bonus* | &nbsp;&nbsp;*Performance Awards* | &nbsp;&nbsp;*Performance Awards* | *RSU's* | *Options* | **Exercise or<br>Base Price<br>of<br>Awards** | **Grant Date**<br>**Fair Value**<br>**of Stock**<br>**Options**<br>**and Awards ($) (2)** |
| *Todd Franklin* |  |  | 463667 | 695500 |  |  |  |  |  |  |
| &nbsp;&nbsp;*Watanabe* | 2/28/2025 |  |  |  |  |  | 151000 |  |  | 2067190 |
|  | 2/28/2025 |  |  |  |  |  |  | 396000 | 13.69 | 3848958 |
| *Latha* |  |  | 170846 | 256268 |  |  |  |  |  |  |
| &nbsp;&nbsp;*Latha Vairavan* | 2/28/2025 |  |  |  |  |  | 11250 |  |  | 154013 |
|  | 2/28/2025 |  |  |  |  |  |  | 23750 | 13.69 | 230840 |
|  | 5/6/2025 | (3) |  |  |  |  | 20000 |  |  | 286400 |
|  | 5/6/2025 | (3) |  |  |  |  |  | 60000 | 14.32 | 608623 |
| *Patrick Burnett* |  |  | 267500 | 401250 |  |  |  |  |  |  |
| &nbsp;&nbsp;*M.D., Ph.D.* | 2/28/2025 | (4) |  |  |  |  | 17000 |  |  | 232730 |
|  | 2/28/2025 |  |  |  |  |  | 38000 |  |  | 520220 |
|  | 2/28/2025 |  |  |  |  |  |  | 99000 | 13.69 | 962240 |
|  | 2/28/2025 | (4) |  |  |  |  |  | 43000 | 13.69 | 417942 |
| *L. Todd* |  |  | 267500 | 401250 |  |  |  |  |  |  |
| &nbsp;&nbsp;*Edwards* | 2/28/2025 | (4) |  |  |  |  | 17000 |  |  | 232730 |
|  | 2/28/2025 |  |  |  |  |  | 38000 |  |  | 520220 |
|  | 2/28/2025 |  |  |  |  |  |  | 99000 | 13.69 | 962240 |
|  | 2/28/2025 | (4) |  |  |  |  |  | 43000 | 13.69 | 417942 |
| *Masaru* |  |  | 222825 | 334237 |  |  |  |  |  |  |
| &nbsp;&nbsp;*Matsuda* | 2/28/2025 |  |  |  |  |  | 34000 |  |  | 465460 |
| &nbsp;&nbsp;*J.D.* | 2/28/2025 |  |  |  |  |  |  | 89000 | 13.69 | 865044 |
| *David Topper* |  | (5) | 238950 | 358425 |  |  |  |  |  |  |
|  | 2/28/2025 |  |  |  |  |  | 34000 |  |  | 465460 |
|  | 2/28/2025 |  |  |  |  |  |  | 89000 | 13.69 | 865044 |

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(1)Amounts represent cash-based annual incentive bonuses for fiscal year 2025, following the achievement of certain corporate goals as determined by the Compensation Committee and as detailed in the heading "Compensation Discussion & Analysis – Evaluation of Performance Against 2025 Corporate Goals". The "maximum" amounts shown in the table above reflect the largest possible payments related to 2025, to be paid in March 2026. There are no minimum thresholds.

(2)Amounts represent the aggregate grant date fair values of the equity awards calculated in accordance with ASC Topic 718. The aggregate grant date fair value for the RSUs was based on the fair value of our common stock on the date of grant, which was determined as the closing market price per share of our common stock on the date of grant. The aggregate grant date fair value for the Stock Options was based on the Black-Scholes option valuation methodology. This calculation is performed for accounting purposes and reported in the table. However, our NEOs may never realize any value from their equity awards. For additional information, refer to Note 10 of the audited financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 for the assumptions used in calculating these amounts.

(3)Ms. Vairavan was promoted to Senior Vice President, Chief Financial Officer on May 6, 2025 and was awarded stock options and RSU's in connection with such promotion.

(4)Mr. Burnett and Mr. Edwards were promoted to Executive Vice President in December 2024. Equity grants associated with these promotions were made in 2025.

(5)Mr. Topper retired on May 15, 2025 and was not paid an annual performance-based cash incentive for 2025. These amounts reflect what he would have been eligible for had he remained employed throughout the year.

**Outstanding Equity Awards at 2025 Fiscal Year End.**

The following table lists all outstanding equity awards held by our NEOs as of December 31, 2025:

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| | | **Option Awards** | **Option Awards** | **Option Awards** | **Option Awards** | **Stock Awards** | **Stock Awards** |
|<br>**Name** |<br>**Vesting** <br>**Commencement** <br>**Date (3)** | **Number of Securities Underlying Unexercised Options Exercisable (#)** | **Number of Securities Underlying Unexercised Options Unexercisable (#)** | **Option Exercise Price ($)** | **Option Expiration Date** | **Number of** <br>**Shares or Units** <br>**of Stock That** <br>**Have Not** <br>**Vested (#) (1)** | **Market Value of Shares or Units of Stock That Have Not Vested ($)(2)** |
| Todd | 3/13/2019 | 267796 |  | 1.68 | 03/13/29 |  |  |
| Franklin | 11/20/2019 | 24991 |  | 6.52 | 11/20/29 |  |  |
| Watanabe | 1/12/2024 | 196458 | 213542 | 3.64 | 01/12/34 |  |  |
|  | 3/1/2025 | 74250 | 321750 | 13.69 | 02/28/35 |  |  |
|  | 3/1/2022 |  |  |  |  | 17725 | 514734 |
|  | 3/1/2023 |  |  |  |  | 43750 | 1270500 |
|  | 2/1/2024 |  |  |  |  | 93750 | 2722500 |
|  | 2/1/2024 (4) |  |  |  |  | 15889 | 461417 |
|  | 2/1/2024 (5) |  |  |  |  | 48375 | 1404810 |
|  | 3/1/2025 |  |  |  |  | 151000 | 4385040 |
| Latha | 3/1/2022 | 5156 | 344 | 17.67 | 03/03/32 |  |  |
| Vairavan | 3/1/2023 | 3438 | 1562 | 15.82 | 03/02/33 |  |  |
|  | 1/12/2024 | 20844 | 22656 | 3.64 | 01/12/34 |  |  |
|  | 3/1/2025 | 4453 | 19297 | 13.69 | 02/28/35 |  |  |
|  | 5/6/2025 | 8750 | 51250 | 14.32 | 05/06/35 |  |  |
|  | 3/1/2022 |  |  |  |  | 2225 | 64614 |
|  | 3/1/2023 |  |  |  |  | 4050 | 117612 |
|  | 2/1/2024 |  |  |  |  | 8625 | 250470 |
|  | 2/1/2024(4) |  |  |  |  | 237 | 6882 |
|  | 3/1/2025 |  |  |  |  | 11250 | 326700 |
|  | 5/1/2025 |  |  |  |  | 20000 | 580800 |
| Patrick | 1/12/2024 |  | 143750 | 3.64 | 01/12/34 |  |  |
| Burnett | 3/1/2025 | 18563 | 80437 | 13.69 | 02/28/35 |  |  |
| M.D., | 3/1/2025 | 8063 | 34937 | 13.69 | 02/28/35 |  |  |
| Ph.D. | 3/1/2022 |  |  |  |  | 4450 | 129228 |
|  | 3/1/2023 |  |  |  |  | 10500 | 304920 |

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| | 2/1/2024 | | | | | 21000 | 609840 |
| | 2/1/2024 (4) | | | | | 4144 | 120342 |
| | 2/1/2024 (5) | | | | | 11625 | 337590 |
| | 3/1/2025 | | | | | 17000 | 493680 |
| | 3/1/2025 | | | | | 38000 | 1103520 |
| | 8/18/2022 (6) | | | | | 4187 | 121590 |
| L.Todd | 10/1/2023 (7) | 130000 | 110000 | 5.58 | 09/27/33 |  |  |
| Edwards | 1/12/2024 | 84333 | 91667 | 3.64 | 01/12/34 |  |  |
|  | 3/1/2025 | 18563 | 80437 | 13.69 | 02/28/35 |  |  |
|  | 3/1/2025 | 8063 | 34937 | 13.69 | 02/28/35 |  |  |
|  | 10/1/2023 |  |  |  |  | 30000 | 871200 |
|  | 2/1/2024 |  |  |  |  | 21000 | 609840 |
|  | 3/1/2025 |  |  |  |  | 17000 | 493680 |
|  | 3/1/2025 |  |  |  |  | 38000 | 1103520 |
| Masaru | 1/12/2024 | 84333 | 91667 | 3.64 | 01/12/34 |  |  |
| Matsuda | 3/1/2025 | 16688 | 72312 | 13.69 | 02/28/35 |  |  |
| J.D. | 3/1/2022 |  |  |  |  | 3325 | 96558 |
|  | 3/1/2023 |  |  |  |  | 10500 | 304920 |
|  | 2/1/2024 |  |  |  |  | 21000 | 609840 |
|  | 2/1/2024 (4) |  |  |  |  | 11456 | 332682 |
|  | 2/1/2024 (5) |  |  |  |  | 11625 | 337590 |
|  | 3/1/2025 |  |  |  |  | 34000 | 987360 |

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(1)Each award is subject to the acceleration of vesting provisions in each named executive officers' severance & change in control agreement.

(2)Based on the closing price of our common stock on December 31, 2025 of $29.04 per share.

(3)Except as otherwise noted, each option vests and becomes exercisable in substantially equal monthly installments over a four year period commencing on the vesting commencement date, subject to the optionee's continuous service to us through the applicable vesting date, and each award of restricted stock units vests in substantially equal annual installments over a four year period commencing on the vesting commencement date, subject to the holder's continuous service to us through the applicable vesting date.

(4)The RSUs vest 1/8 quarterly over a period of two years beginning February 1, 2024, subject to the holder's continuous provision of services to us through each such date.

(5)The RSUs vest 1/12 quarterly over a period of three years beginning February 1, 2024, subject to the holder's continuous provision of services to us through each such date.

(6)The shares vest over a four-year period annually on each anniversary of the vesting commencement date, subject to the holder's continuous provision of services to us through each such date.

(7)The option vests and becomes exercisable as to 1/4th of the original number of shares underlying the option on the first anniversary of the vesting commencement date and as to 1/48th of the original number of shares underlying the option on each monthly anniversary thereafter, subject to the optionee's continuous provision of services to us through such date.

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**Option Exercises and Stock Vested in Fiscal 2025**

The following table summarizes the exercise of options and the vesting of RSUs and PSUs for each of our NEOs during the year ended December 31, 2025:

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| | | | | |
|:---|:---|:---|:---|:---|
| | **Option Awards** | **Option Awards** | **Stock Awards** | **Stock Awards** |
|<br>**Named Executive Officer** | **Number of Securities Acquired on Exercise** | **Value Realized on Exercise ($)(1)** | **Number of Securities Acquired on Vesting** | **Value Realized on Vesting ($)(2)** |
| Todd Franklin Watanabe |  |  | 186700 | 2857824 |
| Latha Vairavan | &nbsp;&nbsp;— | &nbsp;&nbsp;— | &nbsp;&nbsp;11300 | &nbsp;&nbsp;154775 |
| Patrick Burnett, M.D., Ph.D. | &nbsp;&nbsp;74750 | &nbsp;&nbsp;1170346 | 85325 | 1303868 |
| L. Todd Edwards | &nbsp;&nbsp;— | &nbsp;&nbsp;— | &nbsp;&nbsp;52000 | &nbsp;&nbsp;812380 |
| Masaru Matsuda, J.D. |  |  | 80450 | 1342078 |
| David Topper | 95166 | 303519 | 27500 | 411950 |

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(1)The value shown is based on the stock options exercised multiplied by the difference between the price at which they were valued on the date of exercise and the stock option exercise price.

(2)The value shown is the closing price of a share of our Common Stock on the vesting date of RSUs or PSUs, multiplied by the number of units vested.

**Pension Benefits**

We do not have a defined benefit plan. Our named executive officers did not participate in, or otherwise receive, any special benefits under, any pension or defined benefit retirement plan sponsored by us during 2025.

**Nonqualified Deferred Compensation**

During 2025, our named executive officers did not contribute to, or earn any amount with respect to, any defined contribution or other plan sponsored by us that provides for the deferral of compensation on a basis that is not tax-qualified.

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**Equity Compensation Plan Information**

The following table provides certain information as of December 31, 2025, with respect to all of our equity compensation plans in effect on that date:

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| | | | |
|:---|:---|:---|:---|
| **Plan Category** | **Number of Securities to be Issued Upon Exercise of Outstanding Options, Warrants and Rights (a)**  | **Weighted-Average Exercise Price of Outstanding Options, Warrants and Rights (1)** | **Number of Securities Remaining Available for Future Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column (a) (6)** |
| Equity Compensation Plans Approved by Stockholders (2) (3) (4) (5) | 10551206 | $9.39 | 6900421 |
| Equity Compensation Plans Not Approved by Stockholders (7) (8) | 1893281 | $6.97 | 111533 |
| **Total** | 12444487 | $9.17 | 7011954 |

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(1)The weighted-average exercise price is calculated based solely on the exercise prices of the outstanding options and does not reflect shares that will be issued upon the vesting of outstanding RSUs, which have no exercise price.

(2)Includes the 2017 Plan, the 2020 Plan and the 2020 Employee Stock Purchase Plan (the "2020 ESPP").

(3)Amounts include 5,851,828 options outstanding and 4,699,378 RSU's outstanding under the 2020 Equity Incentive Plan (2020 Plan) and 2017 Equity Incentive Plan (2017 Plan), respectively.

(4)The 2020 Plan contains an "evergreen" provision, pursuant to which the number of shares of common stock reserved for issuance or transfer pursuant to awards under the 2020 Plan shall be increased on the first day of each year beginning in 2021 and ending in 2030, equal to the lesser of (i) four percent (4.0%) of the shares of common stock outstanding (on an as converted basis) on the last day of the immediately preceding fiscal year, and (ii) such smaller number of shares of stock as determined by our Board; provided, however, that no more than 11,000,000 shares of stock may be issued upon the exercise of incentive stock options.

(5)The 2020 ESPP contains an "evergreen" provision, pursuant to which the maximum number of shares of our common stock authorized for sale under the 2020 ESPP shall be increased on the first day of each year beginning in 2021 and ending in 2030, equal to the lesser of (i) one percent (1.0%) of the shares of common stock outstanding (on an as converted basis) on the last day of the immediately preceding fiscal year, and (ii) such number of shares of common stock as determined by our Board; provided, however, no more than 5,265,000 shares of our common stock may be issued thereunder.

(6)Includes 2,806,818 shares that were available for future issuance under the 2020 ESPP. The maximum number of shares of our common stock that was purchasable in the offering period that was ongoing as of December 31, 2025 was 876,000.

(7)Includes the 2022 Employment Inducement Incentive Plan (2022 Plan).

(8)Amounts include 585,144 options outstanding and 1,308,137 RSU's outstanding under the 2022 Plan.

***2022 Employment Inducement Incentive Plan ("2022 Plan")***

In December 2021, the Board adopted the Company's 2022 Plan, which provides for the grants of awards of stock options, stock appreciation rights, restricted stock, restricted stock units, performance awards and other stock and cash-based awards to persons who have not previously been an employee or director of the Company, or to an individual following a bona fide period of non-employment with the Company, as an inducement for the individual's entering into employment with the Company. The purpose of the 2022 Plan is to help the Company provide incentives to attract and retain the employment services of new employees, to motivate those new employees whose potential contributions are important to the success of the Company to accept an offer of employment by providing them with equity ownership opportunities, and to advance the interests of the Company's stockholders by providing incentives to those eligible individuals who are expected to make important contributions to the Company.

In the event of any stock split, reverse stock split, stock dividend, recapitalization, combination of shares, reclassification of shares, spin-off or other similar change in capitalization or event, or any dividend or distribution to holders of our common stock other than an ordinary dividend or distribution, the Board will make equitable adjustments, to the number and type of shares reserved for issuance and future grant, the exercise price, number and type of shares subject to outstanding options and share

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appreciation rights and the number and type of shares subject to other outstanding awards in connection with the 2022 Plan.

The 2022 Plan is administered by the Compensation Committee or the Board acting as the Compensation Committee. Subject to the provisions of the 2022 Plan, the administrator has the power to select the recipients of awards, to determine the number of shares subject to any award, to establish and verify the extent of satisfaction of any performance goals or other conditions applicable to awards, to determine whether, and the extent to which, adjustments are required under the 2022 Plan, and to determine the terms and conditions of awards.

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**DIRECTOR COMPENSATION**

**Non-Employee Director Compensation Program**

We maintain a compensation program that was last amended in June 2025 and provides cash and equity compensation to our non-employee directors (the "Non-Employee Director Compensation Program") for their service on the Board and its committees as discussed below. The Non-Employee Director Compensation Program is intended to be fair and competitive to account for the time and effort required of our directors. We do not provide directors who are also our employees any additional compensation for their service as directors.

***Cash Compensation***

Pursuant to the Non-Employee Director Compensation Program, each non-employee director receives an annual retainer of $50,000 (the "Base Retainer"). Non-employee directors are eligible to receive additional annual retainers as follows:

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| | |
|:---|:---|
| | **Amount** |
| Board Chair | $35000 |
| Audit Committee Chair | 20000 |
| Compensation Committee Chair | 15000 |
| Nominating and Corporate Governance Committee Chair | 10000 |
| Audit Committee Member | 10000 |
| Compensation Committee Member | 7500 |
| Nominating and Corporate Governance Committee Member | 5000 |

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The cash compensation set forth above is payable in equal quarterly installments, in arrears following the end of each quarter in which the service occurred, pro-rated for any partial months of service.

We have also reimbursed, and will continue to reimburse, our non-employee directors for their travel, lodging, and other reasonable expenses incurred in attending meetings of our Board and committees of our Board.

***Equity Compensation***

The Non-Employee Director Compensation Program also provides for equity compensation to each non-employee director as compensation for his or her service on the Board. Upon a director's initial appointment or election to our Board, such director automatically receives an award of stock options to purchase shares of our common stock having a grant date fair value of $300,000 (the "Initial Director Grant"). If a director is first appointed or elected on a date other than the date of an Annual Meeting of the Company's stockholders, such director is granted a pro-rated annual equity award that is based on the number of days until the estimated date for the next annual meeting. On an annual basis thereafter, each non-employee director is eligible to receive an award with a value equivalent to $300,000 consisting of (1) stock options having a grant date value of $195,000 (65% of $300,000) and (2) an award of restricted stock units having a grant date value of $105,000 (35% of $300,000) (each of the pro-rata grant and each subsequent annual grant, the "Annual Director Grants").

Each option granted under the Non-Employee Director Compensation Program has an exercise price per share equal to the closing trading price of our common stock on the date of grant. Initial Director Grants vest on each of the first three annual anniversaries of the grant date, subject to the award holder's continued service through each applicable vesting date. Annual Director Grants vest in full on the earlier of the first anniversary of the grant date or immediately before the next annual meeting of stockholders, subject to the award holder's continued service through the applicable vesting date. All equity awards granted to our non-employee directors under the Non-Employee Director Compensation Program will, to the extent they are outstanding and unvested, vest in full immediately prior to the consummation of a

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change in control. Non-employee directors may elect to defer the issuance of shares underlying their RSUs.

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**Director Compensation Table**

The following table sets forth information concerning the compensation earned by our non-employee directors during the year ended December 31, 2025:

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| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Name** | **Fees Earned or Paid in Cash ($)** | | **Option Awards ($) (1)(3)** | **Stock Awards ($) (2)(3)** | **All Other Compensation ($)** | **Total ($)** |
| Bhaskar Chaudhuri, Ph.D. (4) | 60054 |  | 189734 | 102722 |  | 352510 |
| Terrie Curran | 60000 |  | 189734 | 102722 |  | 352456 |
| Halley Gilbert | 60000 |  | 189734 | 102722 |  | 352456 |
| Patrick J. Heron | 57500 | (5) | 189734 | 102722 |  | 349956 |
| Neha Krishnamohan | 60000 |  | 189734 | 102722 |  | 352456 |
| Keith R. Leonard  | 92500 |  | 189734 | 102722 |  | 384956 |
| Sue-Jean Lin | 75000 |  | 189734 | 102722 |  | 367456 |
| Amit Munshi | 4946 | (6) | 401503 | 92794 |  | 499243 |
| Howard G. Welgus, M.D. | 55000 |  | 189734 | 102722 |  | 347456 |

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(1)Amounts reflect the full grant date fair value of stock options granted during 2025 computed in accordance with ASC Topic 718, rather than the amounts paid to or realized by the named individual. See Note 10 of the audited financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 for the assumptions used in calculating these amounts.

(2)Amount reflects the full grant date fair value of restricted stock units granted during 2025 rather than the amounts paid to or realized by the named individual. See Note 10 of the audited financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025 for the assumptions used in calculating these amounts.

(3)As of December 31, 2025, outstanding options and restricted stock units held by our current non-employee directors were as follows:

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| | | | |
|:---|:---|:---|:---|
| **Name** | **Shares Subject to Outstanding Options** | | **Restricted Stock Units (b)** |
| Bhaskar Chaudhuri, Ph.D. | 208992 |  | 7609 |
| Terrie Curran | 122527 |  | 7609 |
| Halley Gilbert | 110307 |  | 7609 |
| Patrick J. Heron | 109027 |  | 7609 |
| Neha Krishnamohan | 50050 |  | 7609 |
| Keith R. Leonard | 104543 |  | 7609 |
| Sue-Jean Lin | 72087 |  | 7609 |
| Amit Munshi | 22679 |  | 3021 |
| Howard G. Welgus, M.D. | 106889 | (a) | 7609 |

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a.21,862 of Dr. Welgus' outstanding stock options related to awards granted as Chief Medical Officer prior to his appointment to the Board of Directors.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;b.Ms. Krishnamohan, Mr. Leonard and Ms. Lin elected to defer receipt of the shares underlying their vested restricted stock units granted in 2023 until the earlier of (i) 5 years from grant, (ii) 6 months after separation from services if a specified employee within the meaning of Section 409A, or (iii) upon a change in control event within the meaning of Section 409A. Ms. Gilbert and Mr. Heron elected to defer receipt of the shares underlying their restricted stock units granted in 2023 until the earlier of (i) 6 months after separation from services if a specified employee within the meaning of Section 409A, or (ii) upon a change in control event within the meaning of Section 409A. For each of the aforementioned directors, 4,375 shares were vested and deferred as of December 31, 2024 and are not reflected in this table.

(4)Mr. Chaudhuri resigned from the board in December 2025. As part of his consulting agreement, his equity will continue to vest until June 30, 2027.

(5)Amount paid to Frazier Healthcare Partners on behalf of Mr. Heron's service as a member of the Board.

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(6)Mr. Munshi was appointed to the Board of Directors on December 4, 2025. As a result, the compensation reported above reflects only the portion of the year during which Mr. Munshi served as a director. In connection with Mr. Munshi's appointment, he received a prorated annual cash retainer and an initial equity award in accordance with the Company's non-employee director compensation program.

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**INFORMATION ABOUT STOCK OWNERSHIP**

**Security Ownership of Certain Beneficial Owners and Management** 

The following table presents information as to the beneficial ownership of our common stock as of April 8, 2026 for:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• each person, or group of affiliated persons, known by us to beneficially own more than 5% of our common stock;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• each named executive officer as set forth in the summary compensation table above;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• each of our directors and nominees; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• all executive officers and directors as a group.

Beneficial ownership is determined in accordance with the rules of the SEC and generally includes voting or investment power with respect to securities. Unless otherwise indicated below, to our knowledge, the persons and entities named in the table have sole voting and sole investment power with respect to all shares beneficially owned, subject to community property laws where applicable. Shares of our common stock subject to options and restricted stock units (including restricted stock units deferred under our Non-Employee Director Compensation Program) that are currently exercisable or vested, or will become exercisable or vested within 60 days of April 8, 2026 are deemed to be outstanding and to be beneficially owned by the person holding the stock options or restricted stock units, as applicable, for the purpose of computing the percentage ownership of that person, but are not treated as outstanding for the purpose of computing the percentage ownership of any other person. Restricted stock units deferred under the deferred compensation feature of our Non-Employee Director Compensation Program (the "DCP") convert into an equivalent number of shares of our common stock on the earlier of (i) the fifth, sixth or seventh anniversary of the grant date, as elected by the director, (ii) cessation of service as a director, (iii) a change in control (as defined), or (iv) death.

Percentage ownership of our common stock in the table is based on shares of our 125,073,249 common stock issued and outstanding on April 8, 2026. This table is based upon information supplied by officers, directors and principal stockholders and Schedules 13D and Schedules 13G, if any, filed with the SEC. Unless otherwise indicated, the address of each of the individuals and entities named below is c/o Arcutis Biotherapeutics, Inc., 3027 Townsgate Road, Suite 300, Westlake Village, CA 91361.

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| | | | | |
|:---|:---|:---|:---|:---|
| | **Shares of Common Stock Beneficially Owned** | **Shares of Common Stock Beneficially Owned** | **Shares of Common Stock Beneficially Owned** | **Shares of Common Stock Beneficially Owned** |
| **Name of Beneficial Owner** | **Common Stock** | **Number of Shares Exercisable Within 60 Days** | **Number of Shares Beneficially Owned** | **Percentage of Shares Beneficially Owned** |
| **5% and Greater Stockholders:** | | | | |
| Suvretta Capital Management, LLC (1) | 9534837 |  | 9534837 | 7.6% |
| BlackRock, Inc. (2) | 9029624 |  | 9029624 | 7.2% |
| Frazier Life Sciences VIII, L.P. (3) | 8785284 |  | 8785284 | 7.0% |
| Rubric Capital Management LP (4) | 8271577 |  | 8271577 | 6.6% |
| Prudential Financial Inc. (5) | 7079926 |  | 7079926 | 5.7% |
| Jennison Associates LLC (6) | 6758006 |  | 6758006 | 5.4% |
| **Named Executive Officers and Directors:** |  |  |  |  |
| Todd Franklin Watanabe (7) | 680766 | 682004 | 1362770 | 1.1% |
| Latha Vairavan (8) | 24542 | 67985 | 92527 | \* |
| Patrick E. Burnett, M.D., Ph.D. (9) | 17163 | 80264 | 97427 | \* |
| L. Todd Edwards (10) | 59928 | 311856 | 371784 | \* |
| Masaru Matsuda, J.D. (11) | 45882 | 138868 | 184750 | \* |
| Howard G. Welgus, M.D. (12) | 32135 | 114498 | 146633 | \* |
| Terrie Curran (13) | 10139 | 130136 | 140275 | \* |
| Halley Gilbert (14) | 14514 | 117916 | 132430 | \* |
| Patrick J. Heron (3)(15) | 8855253 | 116636 | 8971889 | 7.2% |
| Keith Leonard (16) | 16264 | 72880 | 89144 | \* |
| Sue-Jean Lin (17) | 19126 | 79696 | 98822 | \* |
| Neha Krishnamohan (18) | 14514 | 57659 | 72173 | \* |
| Amit Munshi (19) | 2000 | 2021 | 4021 | \* |
| **All executive officers and directors as a group (13 persons)(20)** | 9792226 | 1972419 | 11764645 | 9.4% |

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______________

\*Indicates beneficial ownership of less than 1% of the total outstanding common stock.

(1)As reported on a Schedule 13G/A filed with the SEC on February 13, 2024 by Suvretta Capital Management ("Suvretta"), Averill Master Fund, Ltd ("Averill Fund"), and Aaron Cowen. Suvretta and Mr. Cowen report shared voting and dispositive power over all 9,534,837 shares. Averill Fund directly holds and has shared voting and dispositive power over 8,680,258 shares. The principal business address of Suvretta and Mr. Cowen is 540 Madison Avenue, 7th Floor, New York, NY 10022. The principle business address of Averill Fund is c/o Maples Corporate Services Limited, P.O. Box 309, Ugland House, Grand Cayman KY1-1104,Cayman Islands.

(2)As reported on a Schedule 13G/A filed with the SEC on November 8, 2024 by BlackRock, Inc. reporting beneficial ownership as of September 30, 2024 of shares held by certain subsidiaries, and as to which BlackRock Inc. reports sole voting power over 8,893,485 shares and sole dispositive power over 9,029,624 shares. The principal business address of Blackrock, Inc. is 50 Hudson Yards, New York, NY 10001.

(3)As reported on a Schedule 13D/A filed with the SEC on August 20, 2025 reporting ownership on August 18, 2025 by, among other reporting persons, Frazier Life Sciences VIII, L.P. ("FLS VIII"). James N. Topper and Patrick J. Heron, our director, are the sole members of FHM Life Sciences VIII, L.L.C., the indirect general partner of FLS VIII, and share voting and dispositive power over the shares held by FLS VIII. The principal business address of FLS VIII and Messrs. Topper and Heron is c/o Frazier Life Sciences Management, L.P., 1001 Page Mill Rd, Building 4, Suite B, Palo Alto, CA 94304.

(4)As reported on a Schedule 13G/A filed with the SEC on February 13, 2026 by Rubric Capital Management LP ("Rubric Capital") and David Rosen reporting beneficial ownership as of December 31, 2025 and shared voting and dispositive power over these shares. Rubric Capital is the investment adviser to certain investment funds and/or accounts that hold the shares of Common Stock and David Rosen is the managing member of the general partner of Rubric Capital. The principal business address of Rubric Capital and Mr. Rosen is 155 East 44th St, Suite 1630, New York, NY 10017.

(5)As reported on a Schedule 13G/A filed with the SEC on February 13, 2026 reporting beneficial ownership as of December 31, 2025 by Prudential Financial, Inc., who reports sole power to vote and dispose 45,000 shares, shared power to vote 6,381,022

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shares and shared power to dispose 7,024,926 shares. The shares are beneficially owned by certain of its indirect subsidiaries, including Jennison Associates LLC. See footnote (6). The principal business address of Prudential Financial, Inc. is 751 Broad Street, Newark, New Jersey 07102.

(6)As reported on a Schedule 13G/A filed with the SEC on January 30, 2026 reporting beneficial ownership as of December 31, 2025 by Jennison Associates LLC, who reports shared dispositive and voting power over 6,758,006 shares of our common stock. These shares are also reported as beneficially owned by Prudential Financial, Inc. See footnote (5). The principal business address of Jennison Associates LLC is 466 Lexington Avenue, New York, NY 10017.

(7)Consists of (i) 447,632 shares of our common stock held of record by Todd Franklin Watanabe, (ii) 124,956 shares of our common stock held of record by The Watanabe 2016 Irrevocable Trust, (iii) 57,358 shares of our common stock held of record by Watanabe Ventures, LLC, (iv) 25,410 shares of our common stock held of record by The Anderson Prest Watanabe Irrevocable Trust dated 12 December 2006, (v) 25,410 shares of our common stock held of record by The John Franklin Watanabe Trust dated 25 July 2001, (vi) 672,329 shares of our common stock held by Mr. Watanabe subject to options that are exercisable within 60 days of April 8, 2026, and (vii) 9,675 shares of our common stock held by Mr. Watanabe subject to the vesting of restricted stock units within 60 days of April 8, 2026.

(8)Consists of (i) 24,542 shares of our common stock held of record by Latha Vairavan, (ii) 62,985 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (iii) 5,000 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026.

(9)Consists of (i) 17,163 shares of our common stock held of record by Patrick Burnett, (ii) 77,939 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (iii) 2,325 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026.

(10)Consists of (i) 59,928 shares of our common stock held of record by L. Todd Edwards, and (ii) 311,856 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026.

(11)Consists of (i) 45,882 shares of our common stock held of record by Masaru Matsuda, (ii) 136,543 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (iii) 2,325 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026.

(12)Consists of (i) 32,135 shares of our common stock held of record by Howard G. Welgus, (ii) 106,889 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (iii) 7,609 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026.

(13)Consists of (i) 10,139 shares of our common stock held of record by Terrie Curran, (ii) 122,527 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026 and (iii) 7,609 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026, for which delivery will be deferred under the DCP.

(14)Consists of (i) 10,139 shares of our common stock held of record by Halley Gilbert, (ii) 4,375 restricted (deferred) stock units that have fully vested, which will convert into an equivalent number of shares under the DCP, (iii) 110,307 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (iv) 7,609 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026, for which the delivery will be deferred under the DCP.

(15)Consists of (i) 8,785,284 shares of our common stock held by FLS VIII (see footnote (3)) and 7 shares held by the indirect general partner of FLS VIII; (ii) 27,448 shares of our common stock held by Frazier Life Sciences X, L.P. Mr. Heron is one of two managing members of FHMLS X, L.L.C, the indirect general partner of Frazier Life Sciences X, L.P. and has shared voting and dispositive power over these shares; (iii) 23,688 shares of Common Stock held by The Heron Living Trust 11/30/2004, where Mr. Heron serves as co-trustee and has voting and investment power over these shares; (iv) 14,451 shares of our common stock held of record by Patrick Heron; (v) 4,375 restricted (deferred) stock units held by Mr. Heron that have fully vested, which will convert into an equivalent number of shares under the DCP; (vi) 109,027 shares of our common stock subject to options held by Mr. Heron that are exercisable within 60 days of April 8, 2026; and (vii) 7,609 shares of our common stock held by Mr. Heron subject to the vesting of restricted stock units within 60 days of April 8, 2026, for which the delivery will be deferred under the DCP.

(16)Consists of (i) 10,139 shares of our common stock held of record by Keith Leonard, (ii) 4,375 restricted (deferred) stock units that have fully vested, which will convert into an equivalent number of shares under the DCP, (iii) 1,750 shares of our common stock held of record by the Leonard Family Trust dated August 28, 1996, (iv) 65,271 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (v) 7,609 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026, the delivery of which will be deferred under the DCP.

(17)Consists of (i) 14,751 shares of our common stock held of record by Sue-Jean Lin, (ii) 4,375 restricted (deferred) stock units that have fully vested, which will convert into an equivalent number of shares under the DCP, (iii) 72,087 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, (iv) 4,946 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026, and (v) 2,663 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026, the delivery of which will be deferred under the DCP.

(18)Consists of (i) 10,139 shares of our common stock held of record by Neha Krishnamohan, (ii) 4,375 restricted (deferred) stock units that have fully vested, which will convert into an equivalent number of shares under the DCP, (iii) 50,050 shares of our common stock subject to options that are exercisable within 60 days of April 8, 2026, and (iv) 7,609 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026, for which the delivery will be deferred under the DCP.

(19)Consists of (i) 2,000 shares of our common stock held of record by Amit Munshi, and (ii) 2,021 shares of our common stock subject to the vesting of restricted stock units within 60 days of April 8, 2026.

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(20)Includes (i) 1,897,810 shares subject to options held by all executive officers and directors that are exercisable within 60 days of April 8, 2026, (ii) 33,901 shares of our common stock held by all executive officers and directors subject the vesting of restricted stock units within 60 days of April 8, 2026, and (iii) 40,708 shares restricted (deferred) stock units held by all directors that will vest within 60 days of April 8, 2026, for which the delivery will be deferred under the DCP.

**Delinquent Section 16(a) Reports**

Section 16(a) of the Exchange Act requires our directors and executive officers, and persons who own more than 10% of a registered class of our equity securities, to file with the SEC initial reports of ownership and reports of changes in ownership of our common stock and other equity securities. Officers, directors and greater than 10% stockholders are required by SEC regulations to furnish us with copies of all Section 16(a) forms they file.

To our knowledge, based solely on a review of the copies of such reports furnished to us and written representations that no other reports were required, we believe that all Section 16(a) filing requirements applicable to our officers, directors and greater than 10% beneficial owners were complied with during the year ended December 31, 2025, except, due to an administrative oversight, Mr. Watanabe filed a Form 4 on March 20, 2025 that was one day late, relating to the sale of shares of common stock in one transaction pursuant to a Rule 10b5-1 trading plan, and Mr. Burnett filed a late Form 4 on March 3, 2026, relating to the exempt acquisition of shares from the vesting of three-year performance-based RSUs on August 18, 2025.

**PROPOSAL NO. 3 APPROVAL, ON A NON-BINDING ADVISORY BASIS, OF THE COMPENSATION OF OUR NAMED EXECUTIVE OFFICERS**

**Background**

As required by Section 14A(a)(1) of the Exchange Act, the below resolution enables our stockholders to vote to approve, on a non-binding advisory basis, the compensation of our named executive officers as disclosed in this Proxy Statement. This proposal (the "Say-on-Pay Vote"), and commonly known as a "say-on-pay" proposal, gives our stockholders the opportunity to express their views on our named executive officers' compensation. The Say-on-Pay Vote is not intended to address any specific item of compensation, but rather the overall compensation of our named executive officers and the philosophy, policies and practices described in this Proxy Statement.

We encourage our stockholders to review the "Executive Compensation" section of this Proxy Statement for more information.

As an advisory approval, this proposal is not binding upon us or our Board. However, the Compensation Committee, which is responsible for the design and administration of our executive compensation program, values the opinions of our stockholders expressed through your vote on this proposal. The Board and Compensation Committee will consider the outcome of this vote in making future compensation decisions for our named executive officers. Accordingly, we ask our stockholders to vote "FOR" the following resolution at the Annual Meeting:

"RESOLVED, that the stockholders of Arcutis Biotherapeutics, Inc. approve, on an advisory basis, the fiscal year 2025 compensation of Arcutis Biotherapeutics, Inc.'s named executive officers as described in the "Executive Compensation" section and disclosed in the Summary Compensation Table and related compensation tables and narrative disclosure set forth in Arcutis Biotherapeutics, Inc.'s Proxy Statement for the 2026 Annual Meeting of Stockholders."

**Board Recommendation**

**THE BOARD OF DIRECTORS RECOMMENDS A VOTE "*FOR"* THE RESOLUTION TO APPROVE, ON A NON-BINDING ADVISORY BASIS, THE COMPENSATION OF OUR NAMED EXECUTIVE OFFICERS, AS DISCLOSED IN THE "EXECUTIVE COMPENSATION" SECTION, THE** 

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**ACCOMPANYING COMPENSATION TABLES AND RELATED NARRATIVE DISCLOSURE OF THIS PROXY STATEMENT.** 

**ADDITIONAL INFORMATION**

**Householding of Proxy Materials**

The SEC has adopted rules that permit companies and intermediaries (*e.g*., brokers) to satisfy the delivery requirements for proxy statements and annual reports with respect to two or more stockholders sharing the same address by delivering a single proxy statement addressed to those stockholders. This process, which is commonly referred to as "householding," potentially means extra convenience for stockholders and cost savings for companies.

Brokers with account holders who are our stockholders may be "householding" our proxy materials. A single proxy statement may be delivered to multiple stockholders sharing an address unless contrary instructions have been received from the affected stockholders. Once you have received notice from your broker that it will be "householding" communications to your address, "householding" will continue until you are notified otherwise or until you notify your broker or the Company that you no longer wish to participate in "householding."

If, at any time, you no longer wish to participate in "householding" and would prefer to receive a separate proxy statement and annual report, you may (1) notify your broker, (2) direct your written request to: 3027 Townsgate Road, Suite 300, Westlake Village, CA 91361, or (3) request from Broadridge Financial Solutions, Inc. by calling 1-866-540-7095. Stockholders who currently receive multiple copies of this Proxy Statement at their address and would like to request "householding" of their communications should contact their broker. In addition, the Company will promptly deliver, upon written or oral request to the address or telephone number above, a separate copy of the Form 10-K, Proxy Statement, Proxy Card or Notice of Internet Availability of Proxy Materials to a stockholder at a shared address to which a single copy of the documents was delivered.

**Forward-Looking Statements**

This proxy statement contains "forward-looking statements" (as defined in the Private Securities Litigation Reform Act of 1995). These statements are based on our current expectations and involve risks and uncertainties, which may cause results to differ materially from those set forth in the statements. The forward-looking statements may include statements regarding actions to be taken by us. We undertake no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. Forward-looking statements should be evaluated together with the many uncertainties that affect our business, particularly those mentioned in the risk factors in Item 1A of our Annual Report on Form 10-K for the year ended December 31, 2025 and in our periodic reports on Form 10-Q and our current reports on Form 8-K.

**No Incorporation By Reference**

In our filings with the SEC, information is sometimes "incorporated by reference." This means that we are referring you to information that has previously been filed with the SEC, information that should be considered as part of the filing that you are reading. Based on SEC regulations, the reports of the Audit and Compensation Committees included in this proxy statement are not specifically incorporated by reference into any other filings that we make with the SEC. In addition, references to our website are not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement. Information on our website, other than our proxy statement, Notice of Annual Meeting of Stockholders, and form of proxy, is not part of the proxy soliciting material and is not incorporated herein by reference.

**Other Matters**

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As of the date of this Proxy Statement, the Board does not intend to present any matters other than those described herein at the Annual Meeting and is unaware of any matters to be presented by other parties. If other matters are properly brought before the Annual Meeting for action by the stockholders, proxies will be voted in accordance with the recommendation of the Board or, in the absence of such a recommendation, in the discretion of the proxy holder.

**We have filed our Annual Report on Form 10-K for the year ended December 31, 2025 with the SEC. It is available free of charge at the SEC's web site at www.sec.gov. Upon written request by a stockholder of Arcutis Biotherapeutics, Inc., we will mail without charge a copy of our Annual Report on Form 10-K, including the financial statements and any financial statement schedules, but excluding exhibits to the Annual Report on Form 10-K. Exhibits to the Annual Report on Form 10-K are available upon payment of a reasonable fee, which is limited to our expenses in furnishing the requested exhibit. All requests should be directed to the Corporate Secretary, 3027 Townsgate Road, Suite 300, Westlake Village, CA 91361.**

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| | |
|:---|:---|
| | By Order of the Board of Directors |
| | /s/ Todd Franklin Watanabe |
| | Todd Franklin Watanabe |
| | *President, Chief Executive Officer and Director* |
| April 21, 2026 | |

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**SAMPLE**

![Ballot SCAN TO card ARCUTIS BIOTHERAPEUTICS, INC_Page_1.jpg](arqt-20260421_g5.jpg)

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![Ballot SCAN TO card ARCUTIS BIOTHERAPEUTICS, INC_Page_2.jpg](arqt-20260421_g6.jpg)