# EDGAR Filing Document

**Accession Number:** 0001355064
**File Stem:** 0000910472-26-008194
**Filing Date:** 2026-5
**Character Count:** 23212
**Document Hash:** 485e95f1c0561d70be0261b8c4bd848b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000910472-26-008194.hdr.sgml**: 20260529

**ACCESSION NUMBER**: 0000910472-26-008194

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260529

**DATE AS OF CHANGE**: 20260529

**PERIOD START**: 20260331

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MUTUAL FUND SERIES TRUST
- **CENTRAL INDEX KEY:** 0001355064

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** OH
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-21872
- **FILM NUMBER:** 261039298

**BUSINESS ADDRESS:**
- **STREET 1:** C/O GEMINI FUND SERVICES LLC
- **STREET 2:** 4221 NORTH 203RD STREET, SUITE 100
- **CITY:** ELKHORN
- **STATE:** NE
- **ZIP:** 68022-3474
- **BUSINESS PHONE:** 631 549 1859

**MAIL ADDRESS:**
- **STREET 1:** C/O GEMINI FUND SERVICES LLC
- **STREET 2:** 4221 NORTH 203RD STREET, SUITE 100
- **CITY:** ELKHORN
- **STATE:** NE
- **ZIP:** 68022-3474

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CATALYST FUNDS
- **DATE OF NAME CHANGE:** 20060303

## Series and Classes Contracts Data

### AlphaCentric Life Sciences and Healthcare Fund (Series ID: S000067055)

| Class ID   | Class Name                                             | Ticker Symbol   |
|:---|:---|:---|
| C000215729 | AlphaCentric Life Sciences and Healthcare Fund Class C | LYFCX           |
| C000215730 | AlphaCentric Life Sciences and Healthcare Fund Class I | LYFIX           |
| C000215731 | AlphaCentric Life Sciences and Healthcare Fund Class A | LYFAX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** MUTUAL FUND SERIES TRUST

- **b. Investment Company Act file number:** 811-21872

- **c. CIK number of Registrant:** 0001355064

- **d. LEI of Registrant:** 5493002ZGLQMLR4QMA96

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** C/O GEMINI FUND SERVICES LLC

  - **City:** ELKHORN

  - **State:** NE

  - **Foreign country:** US

  - **Zip / Postal Code:** 68022

  - **Telephone number:** 631-470-2600

**Item A.2. Information about the Series.**

- **a. Name of Series:** AlphaCentric Life Sciences and Healthcare Fund

- **b. EDGAR series identifier (if any):** S000067055

- **c. LEI of Series:** 549300XV4TMPQ6UX8179

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-03-31

- **b. Date as of which information is reported:** 2026-03-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $39404584.00

**Total Liabilities:** $82266.07

**Net Assets:** $39322317.93

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000215729 | 0.90%                | 2.24%                | -3.63%               |
| Class ID C000215730 | 1.01%                | 2.37%                | -3.59%               |
| Class ID C000215731 | 1.01%                | 2.32%                | -3.61%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $51692.41                | $390269.74                                 |
| Month 2  | $1099815.08              | $-176295.56                                |
| Month 3  | $87057.81                | $-1514775.47                               |

### Schedule of Portfolio Investments

| Name                                | Title            | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Adma Biologics Inc                  | ADMA BIOLOGICS I | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10037 | NS      | $90433.37     | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc.                         | ABBVIE INC       | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |      3544 | NS      | $770784.56    | 1.96%             |  |  |  | No            |                  1 | On Loan: No      |
| Abivax SA                           | ABIVAX SA-ADR    | CUSIP: 00370M103<br>LEI: 969500D8TMNB184OJU95 | Long             | EC               | CORP              | FR        |      3424 | NS      | $381262.40    | 0.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc              | SPYRE THERAPEUTI | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |      6634 | NS      | $334618.96    | 0.85%             |  |  |  | No            |                  1 | On Loan: No      |
| Agios Pharmaceuticals Inc           | AGIOS PHARMACEUT | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     13971 | NS      | $472638.93    | 1.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Aldeyra Therapeutics Inc.           | ALDEYRA THERAPEU | CUSIP: 01438T106<br>LEI: 529900HGKY864E4Y9014 | Long             | EC               | CORP              | US        |     37120 | NS      | $62732.80     | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc.        | ALNYLAM PHARMACE | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |      1370 | NS      | $453291.90    | 1.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc.                          | AMGEN INC        | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |      2329 | NS      | $819458.65    | 2.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon Inc                         | ANNEXON INC      | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     24518 | NS      | $135829.72    | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc.            | APOGEE THERAPEUT | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11369 | NS      | $956928.73    | 2.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Argenx SE                           | ARGENX SE - ADR  | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |      1794 | NS      | $1310068.50   | 3.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                         | ARVINAS INC      | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13150 | NS      | $139390.00    | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Ascendis Pharma A/S                 | ASCENDIS PHA-ADR | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |      4526 | NS      | $1035231.98   | 2.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Atrium Therapeutics Inc.            | ATRIUM THERAPEUT | CUSIP: 04965N104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13286 | NS      | $177633.82    | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Avalo Therapeutics Inc              | AVALO THERAPEUTI | CUSIP: 05338F306<br>LEI: 549300GPK6FPJ3X8SZ39 | Long             | EC               | CORP              | US        |     11668 | NS      | $174203.24    | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc.            | AXSOME THERAPEUT | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |      6438 | NS      | $1088150.76   | 2.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                          | BIOGEN INC       | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |      3835 | NS      | $703070.55    | 1.79%             |  |  |  | No            |                  1 | On Loan: No      |
| BioNTech SE                         | BIONTECH SE-ADR  | CUSIP: 09075V102<br>LEI: 894500UZJ5LG1F8J1U58 | Long             | EC               | CORP              | DE        |      5616 | NS      | $499150.08    | 1.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Candel Therapeutics Inc             | CANDEL THERAPEUT | CUSIP: 137404109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     36313 | NS      | $177933.70    | 0.45%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc.       | CATALYST PHARMAC | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |     23286 | NS      | $576561.36    | 1.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc.           | CELLDEX THERAPEU | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |     12614 | NS      | $400116.08    | 1.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc           | CULLINAN THERAPE | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     20135 | NS      | $286118.35    | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                    | CYTOKINETICS INC | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |      5616 | NS      | $370150.56    | 0.94%             |  |  |  | No            |                  1 | On Loan: No      |
| Design Therapeutics Inc.            | DESIGN THERAPEUT | CUSIP: 25056L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     21231 | NS      | $225897.84    | 0.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Disc Medicine Inc                   | DISC MEDICINE IN | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3972 | NS      | $253969.68    | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc.          | EDGEWISE THERAPE | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     15615 | NS      | $491872.50    | 1.25%             |  |  |  | No            |                  1 | On Loan: No      |
| First American Funds Inc.           | FIRST AM-TR OB-X | CUSIP: 31846V328<br>LEI: 549300J5J5SJCZ9IA369 | Long             | STIV             | RF                | US        |   3035293 | PA      | $3035292.53   | 7.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc.                | GILEAD SCIENCES  | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |     20260 | NS      | $2823636.20   | 7.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc           | HALOZYME THERAPE | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |      4794 | NS      | $309836.22    | 0.79%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corporation.                 | INCYTE CORP      | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |     14245 | NS      | $1340739.40   | 3.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                          | INSMED INC       | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |      8583 | NS      | $1403492.16   | 3.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc           | INTELLIA THERAPE | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |     11506 | NS      | $147506.92    | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals, Inc.         | IONIS PHARMACEUT | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |     19587 | NS      | $1470787.83   | 3.74%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc.                 | IQVIA HOLDINGS I | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |       822 | NS      | $140183.88    | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech Inc                 | KRYSTAL BIOTECH  | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |      1918 | NS      | $495457.76    | 1.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc             | KYMERA THERAPEUT | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5342 | NS      | $444935.18    | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics Inc         | MONTE ROSA THERA | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12566 | NS      | $206710.70    | 0.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc.                         | NATERA INC       | CUSIP: 632307104<br>LEI: 529900CQ3OZ0A0VYVU59 | Long             | EC               | CORP              | US        |      1370 | NS      | $273986.30    | 0.70%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc          | NEUROCRINE BIOSC | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |      9607 | NS      | $1265626.18   | 3.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvalent Inc                        | NUVALENT INC-A   | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4657 | NS      | $477109.65    | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics Inc.             | NURIX THERAPEUTI | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     25571 | NS      | $396350.50    | 1.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics Inc              | ORUKA THERAPEUTI | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |     11506 | NS      | $564369.30    | 1.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Personalis Inc                      | PERSONALIS INC   | CUSIP: 71535D106<br>LEI: 549300EZ2NYFK7H0US48 | Long             | EC               | CORP              | US        |     64032 | NS      | $407883.84    | 1.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc        | PROTAGONIST THER | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      9040 | NS      | $952816.00    | 2.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Rapport Therapeutics Inc            | RAPPORT THERAPEU | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6438 | NS      | $201445.02    | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                        | REZOLUTE INC     | CUSIP: 76200L309<br>LEI: 549300T05L48T72P2G08 | Long             | EC               | CORP              | US        |     71227 | NS      | $217242.35    | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc          | RHYTHM PHARMACEU | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |      9297 | NS      | $808560.09    | 2.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Sanofi SA                           | SANOFI-ADR       | CUSIP: 80105N105<br>LEI: 549300E9PC51EN656011 | Long             | EC               | CORP              | FR        |     14382 | NS      | $692924.76    | 1.76%             |  |  |  | No            |                  1 | On Loan: No      |
| Sionna Therapeutics Inc.            | SIONNA THERAPEUT | CUSIP: 829401108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4818 | NS      | $193153.62    | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Tectonic Therapeutic Inc            | TECTONIC THERAPE | CUSIP: 878972108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6849 | NS      | $211702.59    | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |
| Trevi Therapeutics Inc              | TREVI THERAPEUTI | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23970 | NS      | $285962.10    | 0.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                        | VERACYTE INC     | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |      6838 | NS      | $220251.98    | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Incorporated | VERTEX PHARM     | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |      4931 | NS      | $2201888.74   | 5.60%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc        | XERIS BIOPHARMA  | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45886 | NS      | $266138.80    | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| MDXHealth SA                        | MDXHEALTH        | CUSIP: B5950S113<br>LEI: 549300J3MG9F9B5FY646 | Long             | EC               | CORP              | BE        |     32951 | NS      | $75787.30     | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| AstraZeneca PLC                     | ASTRAZENECA PLC  | CUSIP: G0593M107<br>LEI: PY6ZZQWO2IZFZC3IOL08 | Long             | EC               | CORP              | GB        |     11232 | NS      | $2215175.04   | 5.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes PLC                        | ALKERMES PLC CVR | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               |  | IE        |     39859 | NS      | $0.00         | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| Icon PLC                            | ICON PLC         | CUSIP: G4705A100<br>LEI: 6354008SRQGEMC4XFI67 | Long             | EC               | CORP              | IE        |       973 | NS      | $107672.18    | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC            | JAZZ PHARMACEUTI | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | IE        |      3561 | NS      | $673207.05    | 1.71%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings PLC               | MEIRAGTX HOLDING | CUSIP: G59665102<br>LEI: 54930007YV6NYIOGFZ57 | Long             | EC               | CORP              | KY        |     53694 | NS      | $464990.04    | 1.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                | ROIVANT SCIENCES | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | BM        |     47667 | NS      | $1320375.90   | 3.36%             |  |  |  | No            |                  1 | On Loan: No      |
| NewAmsterdam Pharma Company NV      | NEWAMSTERDAM PHA | CUSIP: N62509109<br>LEI: 984500B6549TF6E14D36 | Long             | EC               | CORP              | NL        |     14656 | NS      | $469138.56    | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Wave Life Sciences Ltd.             | WAVE LIFE SCIENC | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | SG        |     29175 | NS      | $211518.75    | 0.54%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-04-28

**Name of Applicant:** MUTUAL FUND SERIES TRUST

**Signature:** Erik Naviloff

**Name of Signer:** Erik Naviloff

**Title:** Treasurer