# EDGAR Filing Document

**Accession Number:** 0000897448
**File Stem:** 0001193125-25-254620
**Filing Date:** 2025-10
**Character Count:** 34202
**Document Hash:** e23925293756a1dffb5ccdf20a39a64f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-254620.hdr.sgml**: 20251029

**ACCESSION NUMBER**: 0001193125-25-254620

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 12

**CONFORMED PERIOD OF REPORT**: 20251029

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20251029

**DATE AS OF CHANGE**: 20251029

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** AMARIN CORP PLC\UK
- **CENTRAL INDEX KEY:** 0000897448
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** X0
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 000-21392
- **FILM NUMBER:** 251426792

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** SPACES SOUTH DOCKLANDS, BLOCK C
- **STREET 2:** 77 SIR JOHN ROGERSON'S QUAY
- **CITY:** DUBLIN 2
- **PROVINCE COUNTRY:** L2
- **BUSINESS PHONE:** 353 1 6699 020

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** SPACES SOUTH DOCKLANDS, BLOCK C
- **STREET 2:** 77 SIR JOHN ROGERSON'S QUAY
- **CITY:** DUBLIN 2
- **PROVINCE COUNTRY:** L2

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** AMARIN PHARMACEUTICALS PLC
- **DATE OF NAME CHANGE:** 20000201

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ETHICAL HOLDINGS PLC
- **DATE OF NAME CHANGE:** 19930322

?xml version='1.0' encoding='ASCII'? 8-K

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**WASHINGTON, D.C. 20549** 

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**FORM** 8-K

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**CURRENT REPORT** 

**Pursuant to Section 13 or 15(d)** 

**of the Securities Exchange Act of 1934** 

**Date of Report (Date of Earliest Event Reported):** October 29, 2025

Amarin Corporation plc

**(Exact name of registrant as specified in its charter)** 

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| | | |
|:---|:---|:---|
| England and Wales | 0-21392 | Not applicable |
| **(State or other jurisdiction**<br>**of incorporation)** | **(Commission**<br>**File Number)** | **(I.R.S. Employer**<br>**Identification No.)** |

---

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| | |
|:---|:---|
| 8th Floor, One Central Plaza, Dame Street**,**<br>Dublin 2, Co. Dublin**,** D02 K7K5**,** Ireland | **Not applicable** |
| **(Address of principal executive offices)** | **(Zip Code)** |

---

**Registrant's telephone number, including area code: +**353 1 6699 020

**Not Applicable** 

**Former name or former address, if changed since last report** 

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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) 

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) 

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) 

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) 

Securities registered pursuant to Section 12(b) of the Act:

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| | | |
|:---|:---|:---|
| **Title of each class** | **Trading Symbol** | **Name of each exchange on which registered** |
| American Depositary Shares (ADS(s)), each ADS representing the right to receive twenty (20) Ordinary Shares of Amarin Corporation plc | AMRN | Nasdaq Stock Market LLC  |

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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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**Item 2.02. Results of Operations and Financial Condition.** 

On October 29, 2025, Amarin Corporation plc ("*Amarin*") issued a press release announcing its financial results for the three and nine months ended September 30, 2025 and 2024 (the "*Press Release*"). A copy of the Press Release is furnished herewith as Exhibit 99.1.

*The information in this report furnished pursuant to Item 2.02 shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section. It may only be incorporated by reference in another filing under the Exchange Act or the Securities Act of 1933, as amended (the "Securities Act"), if such subsequent filing specifically references the information furnished pursuant to Item 2.02 of this report.* 

**Item 9.01. Financial Statements and Exhibits.** 

(d) Exhibits

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| | |
|:---|:---|
| Exhibit No. | Description |
| [<u>99.1</u>](amrn-ex99_1.htm) | &nbsp;&nbsp;&nbsp;[<u>Press Release (results of operations), dated October 29, 2025 (furnished herewith)</u>](amrn-ex99_1.htm) |
| 104 | &nbsp;&nbsp;&nbsp;Cover Page Interactive Data File (embedded within the Inline XBRL document)<br>|

---

\* \* \*

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**SIGNATURES** 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | | |
|:---|:---|:---|
| Date: October 29, 2025 | Amarin Corporation plc | Amarin Corporation plc |
|  | By: | /s/ Aaron Berg<br>|
|  |  | Aaron Berg |
|  |  | President and Chief Executive Officer |

---

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## Exhibit 99.1

**Exhibit 99.1**![img114078973_0.jpg](img114078973_0.jpg)

**Amarin Reports Third Quarter 2025 Financial Results**

*Company completes transition to fully partnered commercialization model across all international markets* 

*Q3 2025 performance reflects initial impact of new approach to Europe, ongoing expansion of* <br>*Rest-of-World demand, continued success in managing US market, and initial operating margin improvements following corporate rightsizing*

*Targeting sustainable positive free cash flow in 2026*

**DUBLIN, Ireland and BRIDGEWATER, N.J., October 29, 2025 --** Amarin Corporation plc (NASDAQ: AMRN), a company committed to advancing the science of cardiovascular care worldwide, today announced financial results for the third quarter of 2025.

"With the reporting of Q3 2025 we usher in the next phase in the Amarin story," said Aaron Berg, President & CEO, Amarin. "Our international commercial strategy is now a fully partnered model comprising seven parties and close to 100 countries with regional and in-country economies of scale, infrastructure and proven experience to commercialize a unique product like VASCEPA®/VAZKEPA® (icosapent ethyl)."

Mr. Berg continued," We are confident in the strategic actions we have taken at Amarin to date and optimistic about the potential of our global business. Meanwhile, we remain focused on additional ways to create value for shareholders. As always, we look forward to reporting on our future progress."

**Q3 2025 Financial Highlights**

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| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;*($ in millions)* | &nbsp;&nbsp;Q3 2025 | &nbsp;&nbsp;Q3 2024 | &nbsp;&nbsp;% Change |
| &nbsp;&nbsp;Total Net Revenue | &nbsp;&nbsp;$49.7 | &nbsp;&nbsp;$42.3 | &nbsp;&nbsp;17% |
| &nbsp;&nbsp;Operating Expenses | &nbsp;&nbsp;$33.3 | &nbsp;&nbsp;$41.4 | &nbsp;&nbsp;(20)% |
| &nbsp;&nbsp;Operating Loss | &nbsp;&nbsp;$11.1 | &nbsp;&nbsp;$25.2 | &nbsp;&nbsp;56% |
| &nbsp;&nbsp;Operating Margin %\* | &nbsp;&nbsp;(22)% | &nbsp;&nbsp;(60)% | &nbsp;&nbsp;NM |
| &nbsp;&nbsp;Net Loss | &nbsp;&nbsp;$7.7 | &nbsp;&nbsp;$25.1 | &nbsp;&nbsp;69% |
| &nbsp;&nbsp;Net Margin | &nbsp;&nbsp;(16)% | &nbsp;&nbsp;(59)% | &nbsp;&nbsp;NM |
| &nbsp;&nbsp;Cash | &nbsp;&nbsp;$286.6 | &nbsp;&nbsp;$305.7 |  |

---

*\*Operating margin is calculated as operating income (loss) divided by total net revenue*

*NM – Not Meaningful*

Commenting on the third quarter and current state of the business, Peter Fishman, Amarin's Chief Financial Officer said, "Our third quarter performance reflects the initial impact following the strategic steps we've taken in creating a different operating profile. Revenues remained stable, supported by ongoing resilience domestically and growing international demand. Operating expenses declined meaningfully, demonstrating the benefits of our global reorganization and continued cost discipline. As we progress with the transition to Recordati, we continue to build

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toward positive free cash flow, which we expect to achieve in 2026. Overall, with the new strategy and foundation in place, Amarin is positioned for steady operating margin and cash flow improvements."

**Q3 2025 Financial Performance**

**<u>Revenues</u>**

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| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;*($ in millions)* | &nbsp;&nbsp;Q3 2025 | &nbsp;&nbsp;Q3 2024 | &nbsp;&nbsp;% Change |
| &nbsp;&nbsp;Product Revenue, net: |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;U.S. | &nbsp;&nbsp;$40.9 | &nbsp;&nbsp;$30.6 | &nbsp;&nbsp;34% |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Europe | &nbsp;&nbsp;$4.1 | &nbsp;&nbsp;$4.3 | &nbsp;&nbsp;(5)% |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Rest-of-World (ROW) | &nbsp;&nbsp;$3.6 | &nbsp;&nbsp;$6.9 | &nbsp;&nbsp;(48)% |
| &nbsp;&nbsp;Total Product Revenue, net | &nbsp;&nbsp;$48.6 | &nbsp;&nbsp;$41.9 | &nbsp;&nbsp;16% |
| &nbsp;&nbsp;Licensing & Royalties | &nbsp;&nbsp;$1.1 | &nbsp;&nbsp;$0.4 | &nbsp;&nbsp;NM |
| &nbsp;&nbsp;Total Net Revenue | &nbsp;&nbsp;$49.7 | &nbsp;&nbsp;$42.3 | &nbsp;&nbsp;17% |

---

*NM – Not Meaningful*

**Total Net Revenue:** For Q3 2025, total net revenue increased $7.4 million, or 17%, compared to Q3 2024, primarily due to higher U.S. sales.

**Product Revenue, Net:** For Q3 2025, product revenue, net increased $6.7 million, or 16%, compared to Q3 2024 primarily due to higher net selling price in the U.S. and an increase in volume driven by regaining exclusive status with a large PBM. The increase was offset by slightly lower Europe sales, reflecting the initial transition to a partnered model with Recordati in this market, as well as lower ROW sales, primarily reflecting normal quarterly variability across the multiple geographies encompassing this early stage of a developing ex-U.S. market.

**Licensing and Royalties:** For Q3 2025, licensing and royalties increased $0.7 million, or 149%, compared to Q3 2024, primarily due to increased royalty revenues from in-market sales generated by the Company's licensed global partners.

**<u>Operating Expenses</u>**

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| | | | |
|:---|:---|:---|:---|
| &nbsp;&nbsp;*($ in millions)* | &nbsp;&nbsp;Q3 2025 | &nbsp;&nbsp;Q3 2024 | &nbsp;&nbsp;% Change |
| &nbsp;&nbsp;COGS | &nbsp;&nbsp;$27.5 | &nbsp;&nbsp;$26.0 | &nbsp;&nbsp;6% |
| &nbsp;&nbsp;SG&A | &nbsp;&nbsp;$19.7 | &nbsp;&nbsp;$36.9 | &nbsp;&nbsp;(47)% |
| &nbsp;&nbsp;R&D | &nbsp;&nbsp;$4.2 | &nbsp;&nbsp;$4.5 | &nbsp;&nbsp;(7)% |
| &nbsp;&nbsp;Restructuring | &nbsp;&nbsp;$9.4 | &nbsp;&nbsp;-- | &nbsp;&nbsp;NM |
| &nbsp;&nbsp;Total Operating Expenses\* | &nbsp;&nbsp;$33.3 | &nbsp;&nbsp;$41.4 | &nbsp;&nbsp;(20)% |

---

 *\* Total operating expenses reflect the sum of SG&A, R&D, and Restructuring expenses.*

*NM – Not Meaningful*

**COGS:** For Q3 2025, cost of goods sold (COGS) increased $1.4 million, or 6%, due primarily to the increase in net product revenue.

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**SG&A:** For Q3 2025, selling general and administrative expenses decreased $17.2 million, or 47%, compared with Q3 2024, primarily due to the impact of the June 2025 restructuring and the continued disciplined management of spending commitments and priorities.

**R&D:** For Q3 2025, research and development expenses decreased $0.3 million, or 7%, compared with Q3 2024.

**Restructuring:** In Q3 2025, the Company recognized $9.4 million in restructuring charges related to the implementation of the Global Restructuring Plan associated with the execution of the Recordati Licensing Agreement announced on June 24, 2025, which resulted in the elimination of commercial roles in the Company's European operations.

**Total Operating Expenses:** For Q3 2025, total operating expenses decreased $8.1 million, or 20%, compared with Q3 2024, due primarily to the impact of the June 2025 operational restructuring. Excluding the restructuring charge of $9.4 million, Q3 2025 total operating expenses were $23.9 million.

Overall, the Company will maintain adequate operating expense levels necessary to support the global VASCEPA/VAZKEPA brand and its partners. Such expenses include: regulatory affairs, nonclinical development, clinical development, biostatistics and data management, medical affairs, medical information, scientific publications, and pharmacovigilance, as well as public company related costs, among others.

**<u>Additional Financial Information</u>**

**Operating Loss:** For Q3 2025, the Company reported an operating loss of $11.1 million, compared with an operating loss of $25.2 million for Q3 2024, an improvement of $14.1 million or 56%. Expressed as a percentage of total net revenue, Q3 2025 operating margin was (22)%compared to (60)% for Q3 2024. In both instances, the Q3 2025 performance primarily reflects the impact of the implementation of the Global Restructuring Plan.

**Net Loss:** For Q3 2025, the Company reported a net loss of $7.7 million, or $0.02 per share, compared to a net loss of $25.1 million, or $0.06 per share in Q3 2024.

**Cash:** As of the end of Q3 2025, the Company reported aggregate cash and investments of $286.6 million, compared to $298.7 million for Q2 2025, reflecting a sequential reduction in cash balance of $12.1 million.

**Debt:** As of the end of Q3 2025, the Company remained debt free.

**Third Quarter 2025 Earnings Conference Call and Webcast Information**

Amarin will host a conference call on October 29, 2025, at 8:00 a.m. ET to discuss this information. The conference call can be accessed on the investor relations section of the Company's website at www.amarincorp.com, or via telephone by dialing 877-545-0523 within the United States, 973-528-0016 from outside the United States, and referencing conference ID 459510. A replay of the call will be made available for a period of two weeks following the conference call. To listen to a replay of the call, dial 877-481-4010 from within the United States and 919-882-2331 from outside of the United States, and reference conference ID 53008. A replay of the call will also be available through the Company's website shortly after the call.

**About Amarin** 

Amarin is a global pharmaceutical company committed to reducing the cardiovascular disease (CVD) burden for patients and communities and to advancing the science of cardiovascular care around the world. We own and support a global branded product approved by multiple regulatory authorities based on a track record of proven

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efficacy and safety and backed by robust clinical trial evidence. Our commercialization model includes a direct sales approach in the U.S. and an indirect distribution strategy internationally, through a syndicate of reputable and well-established partners with significant geographic expertise, covering close to 100 markets worldwide. Our success is driven by a dedicated, talented, and highly skilled team of experts passionate about the fight against the world's leading cause of death, CVD.

**About VASCEPA®/VAZKEPA® (icosapent ethyl) Capsules** 

VASCEPA (icosapent ethyl) capsules are the first prescription treatment approved by the U.S. Food and Drug Administration (FDA) comprised solely of the active ingredient, icosapent ethyl (IPE), a unique form of eicosapentaenoic acid. VASCEPA was launched in the United States in January 2020 as the first drug approved by the U.S. FDA for treatment of the studied high-risk patients with persistent cardiovascular risk despite being on statin therapy. VASCEPA was initially launched in the United States in 2013 based on the drug's initial FDA approved indication for use as an adjunct therapy to diet to reduce triglyceride levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia. Since launch, VASCEPA has been prescribed more than twenty-five million times. VASCEPA is covered by most major medical insurance plans. In addition to the United States, VASCEPA is approved and sold in Canada, China, Australia, Lebanon, the United Arab Emirates, Saudi Arabia, Qatar, Bahrain, and Kuwait. In Europe, in March 2021 marketing authorization was granted to icosapent ethyl in the European Union for the reduction of risk of cardiovascular events in patients at high cardiovascular risk, under the brand name VAZKEPA. In April 2021 marketing authorization for VAZKEPA (icosapent ethyl) was granted in the United Kingdom (applying to England, Scotland, Wales, and Northern Ireland). VAZKEPA (icosapent ethyl) is currently approved and sold in Europe in Sweden, Finland, England/Wales, Spain, Netherlands, Scotland, Greece, Portugal, Italy, Denmark and Austria.

**United States<br>Indications and Limitation of Use** 

VASCEPA is indicated:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•As an adjunct to maximally tolerated statin therapy to reduce the risk of myocardial infarction, stroke, coronary revascularization and unstable angina requiring hospitalization in adult patients with elevated triglyceride (TG) levels (≥ 150 mg/dL) and

oestablished cardiovascular disease or

odiabetes mellitus and two or more additional risk factors for cardiovascular disease.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•As an adjunct to diet to reduce TG levels in adult patients with severe (≥ 500 mg/dL) hypertriglyceridemia.

The effect of VASCEPA on the risk for pancreatitis in patients with severe hypertriglyceridemia has not been determined.

**Important Safety Information** 

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•VASCEPA is contraindicated in patients with known hypersensitivity (e.g., anaphylactic reaction) to VASCEPA or any of its components.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•VASCEPA was associated with an increased risk (3% vs 2%) of atrial fibrillation or atrial flutter requiring hospitalization in a double-blind, placebo-controlled trial. The incidence of atrial fibrillation was greater in patients with a previous history of atrial fibrillation or atrial flutter.

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•It is not known whether patients with allergies to fish and/or shellfish are at an increased risk of an allergic reaction to VASCEPA. Patients with such allergies should discontinue VASCEPA if any reactions occur.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•VASCEPA was associated with an increased risk (12% vs 10%) of bleeding in a double-blind, placebo-controlled trial. The incidence of bleeding was greater in patients receiving concomitant antithrombotic medications, such as aspirin, clopidogrel or warfarin.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Common adverse reactions in the cardiovascular outcomes trial (incidence ≥3% and ≥1% more frequent than placebo): musculoskeletal pain (4% vs 3%), peripheral edema (7% vs 5%), constipation (5% vs 4%), gout (4% vs 3%), and atrial fibrillation (5% vs 4%).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Common adverse reactions in the hypertriglyceridemia trials (incidence >1% more frequent than placebo): arthralgia (2% vs 1%) and oropharyngeal pain (1% vs 0.3%).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Adverse events may be reported by calling 1-855-VASCEPA or the FDA at 1-800-FDA-1088.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;•Patients receiving VASCEPA and concomitant anticoagulants and/or anti-platelet agents should be monitored for bleeding.

**FULL U.S. FDA-APPROVED VASCEPA** PRESCRIBING INFORMATION **CAN BE FOUND AT** WWW.VASCEPA.COM**.**

**Europe** 

For further information about the Summary of Product Characteristics (SmPC) for VAZKEPA® in Europe, please visit: https://www.ema.europa.eu/en/documents/product-information/vazkepa-epar-product-information_en.pdf

Globally, prescribing information varies; refer to the individual country product label for complete information.

**Use of Non-GAAP Adjusted Financial Information** 

Included in this press release are non-GAAP adjusted financial information as defined by U.S. Securities and Exchange Commission Regulation G. The GAAP financial measure is most directly comparable to each non-GAAP adjusted financial measure used or discussed, and a reconciliation of the differences between each non-GAAP adjusted financial measure and the comparable GAAP financial measure, is included in this press release after the condensed consolidated financial statements.

Non-GAAP adjusted net (loss) income was derived by taking GAAP net loss and adjusting it for non-cash stock-based compensation expense, restructuring expense and other one-time expenses. Management uses these non-GAAP adjusted financial measures for internal reporting and forecasting purposes, when publicly providing its business outlook, to evaluate the company's performance and to evaluate and compensate the company's executives. The company has provided these non-GAAP financial measures in addition to GAAP financial results because it believes that these non-GAAP adjusted financial measures provide investors with a better understanding of the company's historical results from its core business operations.

While management believes that these non-GAAP adjusted financial measures provide useful supplemental information to investors regarding the underlying performance of the company's business operations, investors are reminded to consider these non-GAAP measures in addition to, and not as a substitute for, financial performance measures prepared in accordance with GAAP. Non-GAAP measures have limitations in that they do not reflect all the amounts associated with the company's results of operations as determined in accordance with GAAP. In addition, it should be noted that these non-GAAP financial measures may be different from non-GAAP measures used by other companies, and management may utilize other measures to illustrate performance in the future.

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**Forward-Looking Statements** 

This press release contains forward-looking statements which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including beliefs about Amarin's key achievements in 2024 and the potential impact and outlook for achievements in 2025 and beyond; Amarin's 2025 financial outlook and cash position; Amarin's overall efforts to expand access and reimbursement to VAZKEPA across global markets; expectations regarding potential strategic collaboration and licensing agreements with third parties, including our ability to attract additional collaborators, as well as our plans and strategies for entering into potential strategic collaboration and licensing agreements and the overall potential and future success of VASCEPA/VAZKEPA and Amarin that are based on the beliefs and assumptions and information currently available to Amarin.

All statements other than statements of historical fact contained in this press release are forward-looking statements. These forward-looking statements are not promises or guarantees and involve substantial risks and uncertainties. A further list and description of these risks, uncertainties and other risks associated with an investment in Amarin can be found in Amarin's filings with the U.S. Securities and Exchange Commission, including Amarin's quarterly report on Form 10-Q for the period ending September 30, 2025 and annual report on Form 10-K for the fiscal year ended 2024. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date they are made. Amarin undertakes no obligation to update or revise the information contained in its forward-looking statements, whether as a result of new information, future events or circumstances or otherwise. Amarin's forward-looking statements do not reflect the potential impact of significant transactions the company may enter into, such as mergers, acquisitions, dispositions, joint ventures or any material agreements that Amarin may enter into, amend or terminate. Investors and others should note that Amarin communicates with its investors and the public using the company website (www.amarincorp.com), the investor relations website (www.amarincorp.com/investor-relations), including but not limited to investor presentations and investor FAQs, U.S. Securities and Exchange Commission filings, press releases, public conference calls and webcasts.

**Amarin Contact Information**

Media Inquiries:

Tegan Berry

Amarin Corporation plc

PR@amarincorp.com

Investor Inquiries:

Bob Burrows

Western Avenue Advisers LLC

bob.burrows.ext@amarincorp.com

Investor.relations@amarincorp.com

**-Tables to Follow-**

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| | | |
|:---|:---|:---|
| **CONSOLIDATED BALANCE SHEET DATA** | **CONSOLIDATED BALANCE SHEET DATA** | **CONSOLIDATED BALANCE SHEET DATA** |
| **(U.S. GAAP)** | **(U.S. GAAP)** | **(U.S. GAAP)** |
| **Unaudited** | **Unaudited** | **Unaudited** |
|  | **September 30, 2025** | **December 31, 2024** |
|  | **(in thousands)** | **(in thousands)** |
| **ASSETS** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Current Assets: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Cash and cash equivalents | $122802 | $121038 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Restricted cash | 301 | 300 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Short-term investments | 163785 | 173182 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Net income (loss) for EPS<sup>1</sup> - non-GAAP | 127309 | 122279 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Inventory | 184703 | 166048 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Prepaid and other current assets | 29434 | 12552 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current assets | 628334 | 595399 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Earnings (loss) per Ordinary Share: | 13 | 16 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Long-term inventory | 9106 | 64740 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Operating lease right-of-use asset | 7186 | 7592 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Other long-term assets | 1109 | 1213 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Earnings (loss) per ADS: | 14066 | 16389 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**TOTAL ASSETS** | $659814 | $685349 |
| &nbsp;&nbsp;&nbsp;&nbsp;**LIABILITIES AND STOCKHOLDERS' EQUITY** |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Current Liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accounts payable | $36712 | $40366 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accrued expenses and other current liabilities | 145521 | 139583 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total current liabilities | 182233 | 179949 |
| &nbsp;&nbsp;&nbsp;&nbsp;Long-Term Liabilities: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Long-term operating lease liability | 6731 | 7723 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Other long-term liabilities | 11956 | 11501 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total liabilities | 200920 | 199173 |
| &nbsp;&nbsp;&nbsp;&nbsp;Stockholders' Equity: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Common stock | 310019 | 305298 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Additional paid-in capital | 1922351 | 1914750 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Treasury stock | (67356) | (65326) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Accumulated deficit | (1706120) | (1668546) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Total stockholders' equity** | 458894 | 486176 |
| **TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY** | $659814 | $685349 |

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| | | | | |
|:---|:---|:---|:---|:---|
| **CONSOLIDATED STATEMENTS OF OPERATIONS DATA** | **CONSOLIDATED STATEMENTS OF OPERATIONS DATA** | **CONSOLIDATED STATEMENTS OF OPERATIONS DATA** | **CONSOLIDATED STATEMENTS OF OPERATIONS DATA** | **CONSOLIDATED STATEMENTS OF OPERATIONS DATA** |
| **(U.S. GAAP)** | **(U.S. GAAP)** | **(U.S. GAAP)** | **(U.S. GAAP)** | **(U.S. GAAP)** |
| **Unaudited** | **Unaudited** | **Unaudited** | **Unaudited** | **Unaudited** |
|  | **Three months ended September 30,** | **Three months ended September 30,** | **Nine months ended September 30,** | **Nine months ended September 30,** |
|  | **(in thousands, except per share amounts)** | **(in thousands, except per share amounts)** | **(in thousands, except per share amounts)** | **(in thousands, except per share amounts)** |
|  | **2025** | **2024** | **2025** | **2024** |
| Product revenue, net | $48558 | $41852 | $136210 | $144522 |
| Licensing and royalty revenue | 1112 | 446 | 28217 | 21786 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total revenue, net | 49670 | 42298 | 164427 | 166308 |
| Less: Cost of goods sold | 27462 | 26022 | 66728 | 75359 |
| Gross margin | 22208 | 16276 | 97699 | 90949 |
| Operating expenses: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Selling, general and administrative (1) | 19697 | 36904 | 94944 | 115340 |
| &nbsp;&nbsp;&nbsp;&nbsp;Research and development (1) | 4208 | 4540 | 14435 | 14884 |
| &nbsp;&nbsp;&nbsp;&nbsp;Restructuring | 9406 |  | 32165 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Total operating expenses | 33311 | 41444 | 141544 | 130224 |
| Operating loss | (11103) | (25168) | (43845) | (39275) |
| Interest income, net | 2783 | 3374 | 8277 | 10028 |
| Other income, net | 205 | 265 | 372 | 1954 |
| Loss from operations before taxes | (8115) | (21529) | (35196) | (27293) |
| Benefit from (provision for) income taxes | 377 | (3605) | (2378) | (6272) |
| Net loss | $(7738) | $(25134) | $(37574) | $(33565) |
| Loss per Ordinary Share: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | $(0.02) | $(0.06) | $(0.09) | $(0.08) |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | $(0.02) | $(0.06) | $(0.09) | $(0.08) |
| Weighted average Ordinary Shares: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Basic | 415531 | 411150 | 414607 | 410786 |
| &nbsp;&nbsp;&nbsp;&nbsp;Diluted | 415531 | 411150 | 414607 | 410786 |
| (1) - Excluding non-cash stock-based compensation, selling, general and administrative expenses were $17,938 and $33,075 for the three months ended September 30, 2025 and 2024, respectively, and research and development expenses were $3,613 and $3,671, respectively, for the same periods. | (1) - Excluding non-cash stock-based compensation, selling, general and administrative expenses were $17,938 and $33,075 for the three months ended September 30, 2025 and 2024, respectively, and research and development expenses were $3,613 and $3,671, respectively, for the same periods. | (1) - Excluding non-cash stock-based compensation, selling, general and administrative expenses were $17,938 and $33,075 for the three months ended September 30, 2025 and 2024, respectively, and research and development expenses were $3,613 and $3,671, respectively, for the same periods. | (1) - Excluding non-cash stock-based compensation, selling, general and administrative expenses were $17,938 and $33,075 for the three months ended September 30, 2025 and 2024, respectively, and research and development expenses were $3,613 and $3,671, respectively, for the same periods. | (1) - Excluding non-cash stock-based compensation, selling, general and administrative expenses were $17,938 and $33,075 for the three months ended September 30, 2025 and 2024, respectively, and research and development expenses were $3,613 and $3,671, respectively, for the same periods. |

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| | | | | |
|:---|:---|:---|:---|:---|
| **RECONCILIATION OF NON-GAAP NET INCOME (LOSS)** | **RECONCILIATION OF NON-GAAP NET INCOME (LOSS)** | **RECONCILIATION OF NON-GAAP NET INCOME (LOSS)** | **RECONCILIATION OF NON-GAAP NET INCOME (LOSS)** | **RECONCILIATION OF NON-GAAP NET INCOME (LOSS)** |
| **Unaudited** | **Unaudited** | **Unaudited** | **Unaudited** | **Unaudited** |
|  | **Three months ended September 30,** | **Three months ended September 30,** | **Nine months ended September 30,** | **Nine months ended September 30,** |
|  | **(in thousands, except per share amounts)** | **(in thousands, except per share amounts)** | **(in thousands, except per share amounts)** | **(in thousands, except per share amounts)** |
|  | **2025** | **2024** | **2025** | **2024** |
| Net loss for EPS<sup>1</sup> - GAAP | (7738) | (25134) | (37574) | (33565) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Stock-based compensation expense | 2354 | 4698 | 12720 | 14303 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;ADS Ratio Change Fees |  |  | 2015 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Licensing Agreement Fees |  |  | 5038 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Restructuring | 9406 |  | 32165 |  |
| Net income (loss) for EPS<sup>1</sup> - non-GAAP | $4022 | $(20436) | $14364 | $(19262) |
| <sup>1</sup>basic and diluted |  |  |  |  |
| Earnings (loss) per Ordinary Share: |  |  |  |  |
| Basic - non-GAAP | $0.01 | $(0.05) | $0.03 | $(0.05) |
| Diluted - non-GAAP | $0.01 | $(0.05) | $0.03 | $(0.05) |
| Earnings (loss) per ADS: |  |  |  |  |
| Basic - non-GAAP | $0.19 | $(0.99) | $0.69 | $(0.94) |
| Diluted - non-GAAP | $0.19 | $(0.99) | $0.69 | $(0.94) |
| Weighted average Ordinary Shares: |  |  |  |  |
| Basic | 415531 | 411150 | 414607 | 410786 |
| Diluted | 416117 | 411150 | 415127 | 410786 |

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