# EDGAR Filing Document

**Accession Number:** 0000200406
**File Stem:** 0000200406-26-000002
**Filing Date:** 2026-1
**Character Count:** 86121
**Document Hash:** 9995b880704e45c12e444673c0e6446e
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000200406-26-000002.hdr.sgml**: 20260121

**ACCESSION NUMBER**: 0000200406-26-000002

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 17

**CONFORMED PERIOD OF REPORT**: 20260121

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20260121

**DATE AS OF CHANGE**: 20260121

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** JOHNSON & JOHNSON
- **CENTRAL INDEX KEY:** 0000200406
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 221024240
- **STATE OF INCORPORATION:** NJ
- **FISCAL YEAR END:** 1228

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-03215
- **FILM NUMBER:** 26544810

**BUSINESS ADDRESS:**
- **STREET 1:** ONE JOHNSON & JOHNSON PLZ
- **CITY:** NEW BRUNSWICK
- **STATE:** NJ
- **ZIP:** 08933
- **BUSINESS PHONE:** 732-524-2455

**MAIL ADDRESS:**
- **STREET 1:** ONE JOHNSON & JOHNSON PLZ
- **CITY:** NEW BRUNSWICK
- **STATE:** NJ
- **ZIP:** 08933

?xml version='1.0' encoding='ASCII'? jnj-20260121

    

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, DC 20549**

**FORM 8-K** 

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of The**

**Securities Exchange Act of 1934**

**Date of report (Date of earliest event reported):** 

**January 21, 2026**

**Johnson & Johnson** 

**(Exact name of registrant as specified in its charter)**

---

| | | |
|:---|:---|:---|
| **New Jersey** | **1-3215** | **22-1024240** |
| **(State or Other Jurisdiction**<br>**of Incorporation)** | **(Commission File Number)** | **(IRS Employer**<br>**Identification No.)** |

---

**One Johnson & Johnson Plaza, New Brunswick, New Jersey 08933** 

**(Address of Principal Executive Offices)**

 **(Zip Code)** 

**Registrant's telephone number, including area code:**

**732-524-0400** 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

**SECURITIES REGISTERED PURSUANT TO SECTION 12(b) OF THE ACT**

---

| | | |
|:---|:---|:---|
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Title of each class** | **Trading Symbol(s)** | **Name of each exchange on which registered** |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Common Stock, Par Value $1.00 | JNJ | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.150% Notes Due November 2028 | JNJ28 | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.700% Notes due February 2029 | JNJ29B | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.200% Notes Due June 2032 | JNJ32 | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.050% Notes due February 2033 | JNJ33B | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.650% Notes Due May 2035 | JNJ35 | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.350% Notes Due June 2036 | JNJ36A | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.350% Notes due February 2037 | JNJ37B | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.550% Notes Due June 2044 | JNJ44 | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.600% Notes due February 2045 | JNJ45 | New York Stock Exchange |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.700% Notes due February 2055 | JNJ55 | New York Stock Exchange |

---

------

**Item 2.02 Results of operations and financial condition**

On January 21, 2026, Johnson & Johnson (the "Company") issued the attached press release (Exhibit 99.1) announcing its sales and earnings for the fourth quarter and full year ended December 28, 2025.

**Item 9.01 Financial statements and exhibits**

(d)&nbsp;&nbsp;&nbsp;&nbsp;Exhibits.

---

| | |
|:---|:---|
| **Exhibit No.** | **Description of Exhibit** |
| <u>[99.1](a2025q4exhibit991.htm)</u> | <u>[Press Release dated](a2025q4exhibit991.htm)[January](a2025q4exhibit991.htm)[21](a2025q4exhibit991.htm)[, 202](a2025q4exhibit991.htm)[6](a2025q4exhibit991.htm)[for the period ended](a2025q4exhibit991.htm)[December](a2025q4exhibit991.htm)[28, 2025](a2025q4exhibit991.htm)</u> |
| <u>[99.2](a2025q4exhibit992.htm)</u> | <u>[Unaudited Comparative Supplementary Sales Data and Condensed Consolidated Statement of Earnings for the fiscal](a2025q4exhibit992.htm)[fourth](a2025q4exhibit992.htm)[quarter and](a2025q4exhibit992.htm)[full year](a2025q4exhibit992.htm)</u> |
| 104 | The cover page from this Current Report on Form 8-K, formatted in Inline XBRL. |

---

------

Signatures

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: January 21, 2026

---

| | |
|:---|:---|
| | **JOHNSON & JOHNSON** |
| | (Registrant) |
| By: | /s/ **Robert J. Decker, Jr.** |
|  | **Robert J. Decker, Jr.**<br>Controller<br>(Principal Accounting Officer) |

---

## Exhibit 99.1

**Exhibit 99.1**

![jnjlogoa.jpg](jnjlogoa.jpg)

---

| | |
|:---|:---|
| **Media contact:**<br><u>media-relations@its.jnj.com</u> | **Investor contact:** <br><u>investor-relations@its.jnj.com</u> |

---

For immediate release

![image_1a.jpg](image_1a.jpg)

**Johnson & Johnson reports Q4 and Full-Year 2025 results**

***•*** *2025 Fourth-Quarter reported sales growth of 9.1% to $24.6 Billion with operational growth of 7.1%\* and adjusted operational growth of 6.1%\*; 2025 Fourth-Quarter earnings per share (EPS) of $2.10 and adjusted EPS of $2.46, both include $(0.10) due to the acquisition of Halda Therapeutics* 

***•*** *2025 Full-Year reported sales growth of 6.0% to $94.2 Billion with operational growth of 5.3%\* and adjusted operational growth of 4.2%\*; 2025 Full-Year earnings per share (EPS) of $11.03 and adjusted EPS of $10.79, both include $(0.10) due to the acquisition of Halda Therapeutics* 

***•*** *Significant innovation including approvals of CAPLYTA for major depressive disorder and RYBREVANT FASPRO plus LAZCLUZE for non-small cell lung cancer, landmark data for TECVAYLI plus DARZALEX FASPRO as a potential standard of care as early as second line for patients with relapsed/refractory multiple myeloma, the acquisition of Halda Therapeutics, and submission of OTTAVA Robotic Surgical System*

***•*** *Company issues guidance for 2026 with estimated reported sales* *of $100.5 Billion or 6.7% at the midpoint, and adjusted EPS*<sup>4</sup> *of $11.53 or 6.9% at the midpoint*

**New Brunswick, N.J. (January 21, 2026)** – Johnson & Johnson (NYSE: JNJ) today announced results for fourth-quarter and full-year 2025. "2025 was a catapult year for Johnson & Johnson, fueled by the strongest portfolio and pipeline in our history" said Joaquin Duato, Chairman and Chief Executive Officer, Johnson & Johnson. "Last year kicked off a new era of accelerated growth, driven by medical innovation that is transforming lives in our six key businesses: Oncology, Immunology, Neuroscience, Cardiovascular, Surgery, and Vision. In each of these important areas, our leadership is expanding driven by game-changing science and technology."

**Overall financial results**

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| | **Q4** | **Q4** | **Q4** | **Full Year** | **Full Year** | **Full Year** |
|<br>**($ in Millions, except EPS)** | **2025** | **2024** | **% Change** | **2025** | **2024** | **% Change** |
| Reported Sales | $24564 | $22520 | &nbsp;&nbsp;&nbsp;&nbsp;9.1% | $94193 | $88821 | &nbsp;&nbsp;&nbsp;&nbsp;6.0% |
| Net Earnings | &nbsp;&nbsp;&nbsp;&nbsp;$5116 | $3431 | &nbsp;&nbsp;&nbsp;&nbsp;49.1% | $26804 | $14066 | &nbsp;&nbsp;&nbsp;&nbsp;90.6% |
| EPS (diluted) | $2.10 | $1.41 | &nbsp;&nbsp;&nbsp;&nbsp;48.9% | $11.03 | $5.79 | &nbsp;&nbsp;&nbsp;&nbsp;90.5% |
|  | **Q4** | **Q4** | **Q4** | **Full Year** | **Full Year** | **Full Year** |
| **Non-GAAP\* ($ in Millions, except EPS)** | **2025** | **2024** | **% Change** | **2025** | **2024** | **% Change** |
| Operational Sales<sup>1,2</sup> |  |  | 7.1% |  |  | 5.3% |
| Adjusted Operational Sales<sup>1,3</sup> |  |  | 6.1% |  |  | 4.2% |
| Adjusted Net Earnings<sup>1,4</sup> | $6009 | $4946 | 21.5% | $26215 | $24242 | 8.1% |
| Adjusted EPS (diluted)<sup>1,4</sup> | $2.46 | $2.04 | 20.6% | $10.79 | $9.98 | 8.1% |
| Free Cash Flow<sup>5,6</sup> |  |  |  | ~$19,700 | $19842 |  |

---

<sup>1</sup>Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules

<sup>2</sup>Excludes the impact of translational currency

<sup>3</sup>Excludes the net impact of acquisitions and divestitures and translational currency

------

<sup>4</sup>Excludes intangible amortization expense and special items

<sup>5</sup>Non-GAAP measure; defined as cash flow from operating activities, less additions to property, plant and equipment. Cash flow from operations, the most directly comparable GAAP financial measure, will be included in subsequent SEC filings.

<sup>6</sup>Full year 2025 is estimated as of January 21, 2026.

Note: values may have been rounded

**Regional sales results**

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Q4** |  |  |  | **% Change** | **% Change** |  |
| **($ in Millions)** | **2025** | **2024** | **Reported** | **Operational**<sup>1,2</sup> | **Currency** | **Adjusted**<br>**Operational**<sup>1,3</sup> |
| U.S. | $14195  | $13204  | 7.5% | 7.5 | - | 5.7 |
| International | 10369  | 9316 | 11.3 | 6.6 | 4.7 | 6.8 |
| Worldwide | $24564  | $22520  | 9.1% | 7.1 | 2.0 | 6.1 |
| **Full Year** |  |  |  | **% Change** | **% Change** |  |
| **($ in Millions)** | **2025** | **2024** | **Reported** | **Operational**<sup>1,2</sup> | **Currency** | **Adjusted**<br>**Operational**<sup>1,3</sup> |
| U.S. | $53752  | $50302  | 6.9% | 6.9 | - | 4.9 |
| International | 40441  | 38519  | 5.0 | 3.4 | 1.6 | 3.3 |
| Worldwide | $94193  | $88821  | 6.0% | 5.3 | 0.7 | 4.2 |

---

<sup>1</sup>Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules

<sup>2</sup>Excludes the impact of translational currency

<sup>3</sup>Excludes the net impact of acquisitions and divestitures and translational currency

Note: values may have been rounded

**Segment sales results**

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Q4** |  |  |  | **% Change** | **% Change** |  |
| **($ in Millions)** | **2025** | **2024** | **Reported** | **Operational**<sup>1,2</sup> | **Currency** | **Adjusted**<br>**Operational**<sup>1,3</sup> |
| Innovative Medicine | $15763  | $14332 | 10.0% | 7.9 | 2.1 | 6.2 |
| MedTech | 8801 | 8188 | 7.5 | 5.8 | 1.7 | 5.9 |
| Worldwide | $24564  | $22520  | 9.1% | 7.1 | 2.0 | 6.1 |
| **Full Year** |  |  |  | **% Change** | **% Change** |  |
| **($ in Millions)** | **2025** | **2024** | **Reported** | **Operational**<sup>1,2</sup> | **Currency** | **Adjusted**<br>**Operational**<sup>1,3</sup> |
| Innovative Medicine | $60401  | $56964 | 6.0% | 5.3 | 0.7 | 4.1 |
| MedTech | 33792 | 31857 | 6.1 | 5.4 | 0.7 | 4.3 |
| Worldwide | $94193  | $88821  | 6.0% | 5.3 | 0.7 | 4.2 |

---

<sup>1</sup>Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules

<sup>2</sup>Excludes the impact of translational currency

<sup>3</sup>Excludes the net impact of acquisitions and divestitures and translational currency

Note: values may have been rounded

------

**Full-year 2025 segment commentary:**

Operational sales\* reflected below excludes the impact of translational currency.

**Innovative Medicine**

Innovative Medicine worldwide operational sales grew 5.3%\*, with net acquisitions and divestitures positively impacting growth by 1.2% primarily due to CAPLYTA. Growth was driven primarily by DARZALEX, CARVYKTI, ERLEADA, and RYBREVANT/LAZCLUZE in Oncology, TREMFYA and SIMPONI/SIMPONI ARIA in Immunology, and SPRAVATO in Neuroscience. Growth was partially offset by an approximate (1,040) basis points impact from STELARA in Immunology.

**MedTech**

MedTech worldwide operational sales grew 5.4%\*, with net acquisitions and divestitures positively impacting growth by 1.1% primarily due to Shockwave. Growth was driven primarily by electrophysiology products and Abiomed in Cardiovascular and wound closure products in General Surgery.

**Full-year 2026 guidance:**

Johnson & Johnson does not provide GAAP financial measures on a forward-looking basis because the company is unable to predict with reasonable certainty the ultimate outcome of legal proceedings, unusual gains and losses, acquisition-related expenses, and purchase accounting fair value adjustments without unreasonable effort. These items are uncertain, depend on various factors, and could be material to Johnson & Johnson's results computed in accordance with GAAP.

---

| | |
|:---|:---|
| **($ in Billions, except EPS)** | **January 2026** |
| Adjusted Operational Sales<sup>1,2</sup><br>Change vs. Prior Year / Mid-point | 5.4% – 6.4% / 5.9% |
| Operational Sales<sup>2</sup> / Mid-point<br>Change vs. Prior Year / Mid-point | $99.5B – $100.5B / $100.0B<br>5.7% – 6.7% / 6.2% |
| Estimated Reported Sales<sup>3</sup>/ Mid-point<br>Change vs. Prior Year / Mid-point | $100.0B – $101.0B / $100.5B<br>6.2% – 7.2% / 6.7% |
| Adjusted Operational EPS (Diluted)<sup>2,4</sup> / Mid-point<br>Change vs. Prior Year / Mid-point | $11.28 – $11.48 / $11.38<br>4.5% – 6.5% / 5.5% |
| Adjusted EPS (Diluted)<sup>3,4</sup> / Mid-point<br>Change vs. Prior Year / Mid-point | $11.43 – $11.63 / $11.53<br>5.9% – 7.9% / 6.9% |

---

<sup>1</sup>Non-GAAP financial measure; excludes the net impact of acquisitions and divestitures

<sup>2</sup>Non-GAAP financial measure; excludes the impact of translational currency

<sup>3</sup>Calculated using Euro Average Rate: January 2026 = $1.17 (Illustrative purposes only)

<sup>4</sup>Non-GAAP financial measure; excludes intangible amortization expense and special items

Note: percentages may have been rounded

Other modeling considerations will be provided on the <u>webcast</u>.

**Notable announcements in the quarter:**

The information contained in this section should be read together with Johnson & Johnson's other disclosures filed with the Securities and Exchange Commission, including its Current Reports on Form 8-K, Quarterly Reports on Form 10-Q and Annual Reports on Form 10-K. Copies of these filings are available online at <u>www.sec.gov</u>, <u>www.jnj.com</u> or on request from Johnson & Johnson. The reader is also encouraged to review all other news releases and information available in the Investor Relations section of the company's website at <u>Investor News</u>, as well as <u>Innovative Medicine Newsroom</u>, <u>MedTech News & Events</u>, and <u>www.factsabouttalc.com</u>.

------

---

| | | |
|:---|:---|:---|
| **Regulatory** | Johnson & Johnson Submits OTTAVA Robotic Surgical System to the U.S. Food and Drug Administration<sup>1</sup> | <u>Press Release</u> |
|  | Johnson & Johnson Receives FDA Approval for TRUFILL n-BCA Liquid Embolic System for the Treatment of Symptomatic Chronic Subdural Hematoma | <u>Press Release</u> |
|  | U.S. FDA Approval of RYBREVANT FASPRO (amivantamab and hyaluronidase-lpuj) Enables the Simplest, Shortest Administration Time for a First-Line Combination Regimen when Combined with LAZCLUZE (lazertinib) | <u>Press Release</u> |
|  | U.S. FDA approves AKEEGA as the first precision therapy for BRCA2-mutated metastatic castration-sensitive prostate cancer with 54% reduction in disease progression vs standard of care | <u>Press Release</u> |
|  | DARZALEX FASPRO is the first and only treatment approved by the U.S. FDA for patients with high-risk smoldering multiple myeloma | <u>Press Release</u> |
|  | FDA approval of CAPLYTA (lumateperone) has the potential to reset treatment expectations, offering hope for remission in adults with major depressive disorder | <u>Press Release</u> |
| **Data Releases** | New clinical data highlights CAPLYTA (lumateperone) as a promising option for achieving remission in adults with major depressive disorder<sup>1</sup> | <u>Press Release</u> |
|  | TECVAYLI monotherapy demonstrates superior progression-free and overall survival versus standard of care as early as first relapse in patients with multiple myeloma predominantly refractory to anti-CD38 therapy and lenalidomide<sup>1</sup> | <u>Press Release</u> |
|  | RYBREVANT (amivantamab-vmjw) longer-term results show promising and durable responses in difficult-to-treat colorectal cancer<sup>1</sup> | <u>Press Release</u> |
|  | Johnson & Johnson unveils new data showing nipocalimab is the first and only investigational FcRn blocker with potential to reduce systemic lupus erythematosus (SLE) activity in a Phase 2 study<sup>1</sup> | <u>Press Release</u> |
|  | Unprecedented results from the Phase 3 MajesTEC-3 study support TECVAYLI plus DARZALEX FASPRO as a potential standard of care as early as second line for patients with relapsed/refractory multiple myeloma | <u>Press Release</u> |
|  | Earlier use of CARVYKTI demonstrated lasting treatment-free remissions at 2.5 years in patients with relapsed or refractory multiple myeloma | <u>Press Release</u> |
|  | Johnson & Johnson's INLEXZO (gemcitabine intravesical system) delivers 74 percent disease-free survival at one year in BCG-unresponsive, high-risk, papillary-only NMIBC | <u>Press Release</u> |
|  | New long-term data reinforces TREMFYA (guselkumab) as the only IL-23 inhibitor proven to substantially inhibit structural joint damage in active psoriatic arthritis | <u>Press Release</u> |
|  | Johnson & Johnson announces first head-to-head study comparing IMAAVY with an alternative FcRn blocker in generalized myasthenia gravis (gMG) at AANEM Annual Meeting | <u>Press Release</u> |
|  | Icotrokinra maintains standout combination of therapeutic benefit and a favorable safety profile in once-daily pill through 28 weeks in ulcerative colitis | <u>Press Release</u> |
|  | TREMFYA (guselkumab), the first and only IL-23 inhibitor with a fully subcutaneous treatment regimen, demonstrates durable remission in Crohn's disease at two years | <u>Press Release</u> |
|  | Published in The Lancet: Nipocalimab significantly decreased Sjögren's disease (SjD) activity and severity through substantial reduction in Sjögren's-related autoantibodies | <u>Press Release</u> |

---

------

---

| | | |
|:---|:---|:---|
| | Icotrokinra long-term results affirm promise of targeted oral peptide with high rates of durable skin clearance and favorable safety profile in difficult-to-treat scalp and genital psoriasis | <u>Press Release</u> |
| | Subcutaneous amivantamab delivers promising 45 percent overall response rate with median duration of 7.2 months in recurrent or metastatic head and neck cancer | <u>Press Release</u> |
| | TECVAYLI plus DARZALEX FASPRO combination regimen significantly improves progression-free survival and overall survival versus standard of care | <u>Press Release</u> |
| <br>**Other** | Johnson & Johnson Reaches Agreement with U.S. Government to Improve Access to Medicines and Lower Costs for Millions of Americans; Delivers on U.S. Manufacturing and Innovation Investments<sup>1</sup> | <u>Press Release</u> |
| <br>**Other** | Johnson & Johnson completes acquisition of Halda Therapeutics and its novel platform to revolutionize cancer treatment and enable next-generation oral therapies | <u>Press Release</u> |
| <br>**Other** | Johnson & Johnson Announces Intent to Separate Its Orthopaedics Business | <u>Press Release</u> |

---

<sup>1</sup>Subsequent to the quarter

**Webcast information:**

Johnson & Johnson will conduct a conference call with investors to discuss this earnings release today at 8:30 a.m., Eastern Time. A simultaneous webcast of the call for investors and other interested parties may be accessed by visiting the <u>Johnson & Johnson website</u>. A replay and podcast will be available approximately two hours after the live webcast in the Investor Relations section of the company's website at <u>events-and-presentations</u>.

**About Johnson & Johnson:**

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at <u>www.jnj.com</u>.

**Non-GAAP financial measures:**

\* "Operational sales growth" excluding the impact of translational currency, "adjusted operational sales growth" excluding the net impact of acquisitions and divestitures and translational currency, as well as "adjusted net earnings", "adjusted diluted earnings per share" and "adjusted operational diluted earnings per share" excluding after-tax intangible amortization expense and special items, are non-GAAP financial measures and should not be considered replacements for, and should be read together with, the most comparable GAAP financial measures. Except for guidance measures, reconciliations of these non-GAAP financial measures to the most directly comparable GAAP financial measures can be found in the accompanying financial schedules of the earnings release and the Investor Relations section of the company's website at <u>quarterly results</u>.

Copies of the financial schedules accompanying this earnings release are available on the company's website at <u>quarterly results</u>. These schedules include supplementary sales data, a condensed consolidated statement of earnings, reconciliations of non-GAAP financial measures, and sales of key products/franchises. Additional information on Johnson & Johnson, including adjusted income before tax by segment, an <u>Innovative Medicine pipeline</u> of selected compounds in late stage development and a copy of today's earnings call presentation can also be found in the Investor Relations section of the company's website at <u>quarterly results</u>.

------

**Note to investors concerning forward-looking statements:** 

This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things: future operating and financial performance, product development, and market position and business strategy. The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Johnson & Johnson. Risks and uncertainties include, but are not limited to: economic factors, such as interest rate and currency exchange rate fluctuations or changes to applicable laws and regulations; competition, including technological advances, new products and patents attained by competitors; challenges inherent in new product research and development, including uncertainty of clinical success and obtaining regulatory approvals; uncertainty of commercial success for new and existing products; challenges to patents; the impact of patent expirations; the ability of the Company to successfully execute strategic plans, including restructuring plans; the impact of business combinations and divestitures; manufacturing difficulties or delays, internally or within the supply chain; product efficacy or safety concerns resulting in product recalls or regulatory action; significant adverse litigation or government action, including related to product liability claims; changes to applicable laws and regulations, including tax laws and global health care reforms; trends toward health care cost containment; changes in behavior and spending patterns of purchasers of health care products and services; financial instability of international economies and legal systems and sovereign risk; and increased scrutiny of the health care industry by government agencies. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson's most recent Annual Report on Form 10-K, including in the sections captioned "Cautionary Note Regarding Forward-Looking Statements" and "Item 1A. Risk Factors," and in Johnson & Johnson's subsequent Quarterly Reports on Form 10-Q and other filings with the Securities and Exchange Commission. Copies of these filings are available online at <u>www.sec.gov</u>, <u>www.jnj.com</u>, <u>investor.jnj.com</u>, or on request from Johnson & Johnson. Any forward-looking statement made in this release speaks only as of the date of this release. Johnson & Johnson does not undertake to update any forward-looking statement as a result of new information or future events or developments.

## Exhibit 99.2

**Exhibit 99.2**

**Johnson & Johnson and subsidiaries**

**Supplementary sales data**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **Percent Change** | **Percent Change** | **Percent Change** |
| **(Unaudited; Dollars in Millions)**<br>**Sales to customers by geographic area** | **2025** | **2024** | **Total** | **Operations** | **Currency** |
| U.S. | **$14195** | **13204** | 7.5% | 7.5 |  |
| Europe | **5598** | **4921** | 13.8 | 5.2 | 8.6 |
| Western Hemisphere excluding U.S. | **1271** | **1135** | 12.0 | 11.0 | 1.0 |
| Asia-Pacific, Africa | **3500** | **3260** | 7.4 | 7.2 | 0.2 |
| International | **10369** | **9316** | 11.3 | 6.6 | 4.7 |
| Worldwide | **$24564** | **22520** | 9.1% | 7.1 | 2.0 |

---

**Note:** Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

------

**Johnson & Johnson and subsidiaries**

**Supplementary sales data**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **Percent Change** | **Percent Change** | **Percent Change** |
| **(Unaudited; Dollars in Millions)**<br>**Sales to customers by geographic area** | **2025** | **2024** | **Total** | **Operations** | **Currency** |
| U.S. | **$53752** | **50302** | 6.9% | 6.9 |  |
| Europe | **21535** | **20212** | 6.5 | 2.4 | 4.1 |
| Western Hemisphere excluding U.S. | **4875** | **4714** | 3.4 | 8.4 | (5.0) |
| Asia-Pacific, Africa | **14031** | **13593** | 3.2 | 3.1 | 0.1 |
| International | **40441** | **38519** | 5.0 | 3.4 | 1.6 |
| Worldwide | **$94193** | **88821** | 6.0% | 5.3 | 0.7 |

---

**Note:** Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

------

**Johnson & Johnson and subsidiaries**

**Supplementary sales data**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **Percent Change** | **Percent Change** | **Percent Change** |
| **(Unaudited; Dollars in Millions)**<br>**Sales to customers by segment of business** | **2025** | **2024** | **Total** | **Operations** | **Currency** |
| Innovative Medicine |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | $**9689** | **8977** | 7.9% | 7.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;International | **6074** | **5355** | 13.4 | 7.9 | 5.5 |
|  | **15763** | **14332** | 10.0 | 7.9 | 2.1 |
| MedTech |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | **4506** | **4227** | 6.6 | 6.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;International | **4295** | **3961** | 8.5 | 4.9 | 3.6 |
|  | **8801** | **8188** | 7.5 | 5.8 | 1.7 |
| U.S. | **14195** | **13204** | 7.5 | 7.5 |  |
| International | **10369** | **9316** | 11.3 | 6.6 | 4.7 |
| Worldwide | $**24564** | **22520** | 9.1% | 7.1 | 2.0 |

---

**Note:** Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

------

**Johnson & Johnson and subsidiaries**

**Supplementary sales data**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **Percent Change** | **Percent Change** | **Percent Change** |
| **(Unaudited; Dollars in Millions)**<br>**Sales to customers by segment of business** | **2025** | **2024** | **Total** | **Operations** | **Currency** |
| Innovative Medicine |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | $**36344** | **33970** | 7.0% | 7.0 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;International | **24057** | **22994** | 4.6 | 2.9 | 1.7 |
|  | **60401** | **56964** | 6.0 | 5.3 | 0.7 |
| MedTech |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | **17408** | **16332** | 6.6 | 6.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;International | **16384** | **15525** | 5.5 | 4.1 | 1.4 |
|  | **33792** | **31857** | 6.1 | 5.4 | 0.7 |
| U.S. | **53752** | **50302** | 6.9 | 6.9 |  |
| International | **40441** | **38519** | 5.0 | 3.4 | 1.6 |
| Worldwide | $**94193** | **88821** | 6.0% | 5.3 | 0.7 |

---

**Note:** Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

------

**Johnson & Johnson and subsidiaries**

**Condensed consolidated statement of earnings**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **(Unaudited; in Millions Except Per Share Figures)** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
|  | **2025** | **2025** | **2024** | **2024** | **Percent<br>Increase<br>(Decrease)** |
|  | **Amount** | **Percent<br>to Sales** | **Amount** | **Percent<br>to Sales** | **Percent<br>Increase<br>(Decrease)** |
| **Sales to customers** | $**24564** | **100.0** | $**22520** | **100.0** | 9.1 |
| **Cost of products sold** | **7968** | **32.4** | **7128** | **31.6** | 11.8 |
| **Gross Profit** | **16596** | **67.6** | **15392** | **68.4** | 7.8 |
| **Selling, marketing and administrative expenses** | **6753** | **27.5** | **6453** | **28.6** | 4.6 |
| **Research and development expense** | **4252** | **17.3** | **5298** | **23.5** | (19.7) |
| **In-process research and development impairments** | **81** | **0.3** | **17** | **0.1** |  |
| **Interest (income) expense, net** | **(23)** | **(0.1)** | **(144)** | **(0.6)** |  |
| **Other (income) expense, net** | **483** | **2.0** | **(161)** | **(0.7)** |  |
| **Restructuring** | **84** | **0.4** | **42** | **0.2** |  |
| **Earnings before provision for taxes on income** | **4966** | **20.2** | **3887** | **17.3** | 27.8 |
| **(Benefit from)/Provision for taxes on income** | **(150)** | **(0.6)** | **456** | **2.1** | (132.9) |
| **Net earnings** | $**5116** | **20.8** | $**3431** | **15.2** | 49.1 |
| **Net earnings per share (Diluted)** | $**2.10** |  | $**1.41** |  | 48.9 |
| **Average shares outstanding (Diluted)** | **2439.0** |  | **2427.1** |  |  |
| **Effective tax rate** | **(3.0)%** |  | **11.7%** |  |  |
| **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> | **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> | **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> | **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> |  |  |
| **Earnings before provision for taxes on income** | $**7046** | **28.7** | $**5421** | **24.1** | 30.0 |
| **Net earnings** | $**6009** | **24.5** | $**4946** | **22.0** | 21.5 |
| **Net earnings per share (Diluted)** | $**2.46** |  | $**2.04** |  | 20.6 |
| **Effective tax rate** | **14.7%** |  | **8.8%** |  |  |

---

<sup>(1)</sup> See Reconciliation of Non-GAAP Financial Measures.

<sup>(A)</sup>&nbsp;&nbsp;&nbsp;&nbsp;NON-GAAP FINANCIAL MEASURES "Adjusted earnings before provision for taxes on income," "adjusted net earnings," "adjusted net earnings per share (diluted)," and "adjusted effective tax rate" are non-GAAP financial measures and should not be considered replacements for GAAP results. The Company provides earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate on an adjusted basis because management believes that these measures provide useful information to investors. Among other things, these measures may assist investors in evaluating the Company's results of operations period over period. In various periods, these measures may exclude such items as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters). Special items may be highly variable, difficult to predict, and of a size that sometimes has substantial impact on the Company's reported results of operations for a period. Management uses these measures internally for planning, forecasting and evaluating the performances of the Company's businesses, including allocating resources and evaluating results relative to employee performance compensation targets. Unlike earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate prepared in accordance with GAAP, adjusted earnings before provision for taxes on income, adjusted net earnings, adjusted net earnings per share (diluted), and adjusted effective tax rate may not be comparable with the calculation of similar measures for other companies. The limitations of using these non-GAAP financial measures as performance measures are that they provide a view of the Company's results of operations without including all events during a period, such as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters) and do not provide a comparable view of the Company's performance to other companies in the health care industry. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP.

------

**Johnson & Johnson and subsidiaries**

**Condensed consolidated statement of earnings**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **(Unaudited; in Millions Except Per Share Figures)** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
|  | **2025** | **2025** | **2024** | **2024** | **Percent<br>Increase<br>(Decrease)** |
|  | **Amount** | **Percent<br>to Sales** | **Amount** | **Percent<br>to Sales** | **Percent<br>Increase<br>(Decrease)** |
| **Sales to customers** | $**94193** | **100.0** | $**88821** | **100.0** | 6.0 |
| **Cost of products sold** | **30256** | **32.1** | **27471** | **30.9** | 10.1 |
| **Gross Profit** | **63937** | **67.9** | **61350** | **69.1** | 4.2 |
| **Selling, marketing and administrative expenses** | **23676** | **25.1** | **22869** | **25.7** | 3.5 |
| **Research and development expense** | **14665** | **15.6** | **17232** | **19.4** | (14.9) |
| **In-process research and development impairments** | **81** | **0.1** | **211** | **0.2** |  |
| **Interest (income) expense, net** | **(85)** | **(0.1)** | **(577)** | **(0.6)** |  |
| **Other (income) expense, net** | **(7209)** | **(7.6)** | **4694** | **5.3** |  |
| **Restructuring** | **228** | **0.2** | **234** | **0.3** |  |
| **Earnings before provision for taxes on income** | **32581** | **34.6** | **16687** | **18.8** | 95.2 |
| **Provision for taxes on income** | **5777** | **6.1** | **2621** | **3.0** | 120.4 |
| **Net earnings** | $**26804** | **28.5** | $**14066** | **15.8** | 90.6 |
| **Net earnings per share (Diluted)** | $**11.03** |  | $**5.79** |  | 90.5 |
| **Average shares outstanding (Diluted)** | **2429.4** |  | **2429.4** |  |  |
| **Effective tax rate** | **17.7%** |  | **15.7%** |  |  |
| **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> | **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> | **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> | **Adjusted earnings before provision for taxes and net earnings** <sup>(1) (A)</sup> |  |  |
| **Earnings before provision for taxes on income** | $**31681** | **33.6** | $**28979** | **32.6** | 9.3 |
| **Net earnings** | $**26215** | **27.8** | $**24242** | **27.3** | 8.1 |
| **Net earnings per share (Diluted)** | $**10.79** |  | $**9.98** |  | 8.1 |
| **Effective tax rate** | **17.3%** |  | **16.3%** |  |  |

---

<sup>(1)</sup> See Reconciliation of Non-GAAP Financial Measures.

<sup>(A)</sup>&nbsp;&nbsp;&nbsp;&nbsp;NON-GAAP FINANCIAL MEASURES "Adjusted earnings before provision for taxes on income," "adjusted net earnings," "adjusted net earnings per share (diluted)," and "adjusted effective tax rate" are non-GAAP financial measures and should not be considered replacements for GAAP results. The Company provides earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate on an adjusted basis because management believes that these measures provide useful information to investors. Among other things, these measures may assist investors in evaluating the Company's results of operations period over period. In various periods, these measures may exclude such items as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters). Special items may be highly variable, difficult to predict, and of a size that sometimes has substantial impact on the Company's reported results of operations for a period. Management uses these measures internally for planning, forecasting and evaluating the performances of the Company's businesses, including allocating resources and evaluating results relative to employee performance compensation targets. Unlike earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate prepared in accordance with GAAP, adjusted earnings before provision for taxes on income, adjusted net earnings, adjusted net earnings per share (diluted), and adjusted effective tax rate may not be comparable with the calculation of similar measures for other companies. The limitations of using these non-GAAP financial measures as performance measures are that they provide a view of the Company's results of operations without including all events during a period, such as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters) and do not provide a comparable view of the Company's performance to other companies in the health care industry. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP.

------

**Johnson & Johnson and subsidiaries**

**Reconciliation of non-GAAP financial measures**

---

| | | |
|:---|:---|:---|
| | **Fourth Quarter** | **Fourth Quarter** |
|<br>**(Dollars in Millions Except Per Share Data)** | **2025** | **2024** |
| Net Earnings, after tax- as reported | **$5116** | **$3431** |
| *Pre-tax Adjustments* |  |  |
| Litigation related | 854 | (16) |
| Intangible Asset Amortization expense | 1186 | 1171 |
| Restructuring related <sup>1</sup> | 210 | 62 |
| Acquisition, integration and divestiture related | (190) | 298 |
| IPR&D impairments | 81 | 17 |
| (Gains)/losses on securities | (100) | (68) |
| Orthopaedics Separation related | 48 |  |
| COVID-19 Vaccine related costs |  | 23 |
| Medical Device Regulation |  | 47 |
| Other | (9) |  |
| *Tax Adjustments* |  |  |
| Tax impact on special item adjustments <sup>2</sup> | (445) | (80) |
| Tax legislation and other tax related | (742) | 61 |
| Adjusted Net Earnings, after tax | **$6009** | **$4946** |
| Average shares outstanding (Diluted) | 2439.0 | 2427.1 |
| Adjusted net earnings per share (Diluted) | **$2.46** | **$2.04** |
| Operational adjusted net earnings per share (Diluted) | **$2.35** |  |

---

**Notes:**

<sup>1</sup>In fiscal 2023, the company completed a prioritization of its research and development (R&D) investment within the Innovative Medicine segment to focus on the most promising medicines with the greatest benefit to patients. This resulted in the exit of certain programs within therapeutic areas. The R&D program exits were primarily in infectious diseases and vaccines including the discontinuation of its respiratory syncytial virus (RSV) adult vaccine program, hepatitis and HIV development. The restructuring expense of $102 million in fiscal 2024 included the termination of partnered and non-partnered program costs, asset impairments and asset divestments. This program was completed in Q4 2024.

In fiscal 2023, the company initiated a restructuring program of its Orthopaedics franchise within the MedTech segment to streamline operations by exiting certain markets, product lines and distribution network arrangements. The restructuring expense of $162 million in the fiscal fourth quarter of 2025 ($307 million Q4 2025 YTD) and $60 million in the fiscal fourth quarter of 2024 ($167 million Q4 2024 YTD) primarily includes costs related to market and product exits. This program was substantially completed in Q4 2025.

In fiscal 2025, the company initiated a restructuring program of its Surgery franchise within the MedTech segment to simplify and focus operations by exiting certain non-strategic product lines and optimize select sites across the network. The restructuring expense of $48 million in the fiscal fourth quarter of 2025 ($205 million Q4 2025 YTD) primarily includes costs related to asset impairments and market and product exits. This program is expected to be substantially completed by the end of fiscal year 2026.

<sup>2</sup>The tax impact related to special item adjustments reflects the current and deferred income taxes associated with the above pre-tax special items in arriving at adjusted earnings.

------

**Johnson & Johnson and subsidiaries**

**Reconciliation of non-GAAP financial measures**

---

| | | |
|:---|:---|:---|
| | **Twelve Months Ended** | **Twelve Months Ended** |
|<br>**(Dollars in Millions Except Per Share Data)** | **2025** | **2024** |
| Net Earnings, after tax- as reported | **$26804** | **$14066** |
| *Pre-tax Adjustments* |  |  |
| Litigation related | (6040) | 5450 |
| Intangible Asset Amortization expense | 4621 | 4526 |
| Restructuring related <sup>1</sup> | 512 | 269 |
| Acquisition, integration and divestiture related | 285 | 1226 |
| IPR&D impairments | 81 | 211 |
| (Gains)/losses on securities | (427) | 306 |
| Orthopaedics Separation related | 48 |  |
| COVID-19 Vaccine related costs |  | 100 |
| Medical Device Regulation |  | 204 |
| Other | 20 |  |
| *Tax Adjustments* |  |  |
| Tax impact on special item adjustments <sup>2</sup> | 381 | (2135) |
| Tax legislation and other tax related | (70) | 19 |
| Adjusted Net Earnings, after tax | **$26215** | **$24242** |
| Average shares outstanding (Diluted) | 2429.4 | 2429.4 |
| Adjusted net earnings per share (Diluted) | **$10.79** | **$9.98** |
| Operational adjusted net earnings per share (Diluted) | **$10.58** |  |

---

**Notes:**

<sup>1</sup>In fiscal 2023, the company completed a prioritization of its research and development (R&D) investment within the Innovative Medicine segment to focus on the most promising medicines with the greatest benefit to patients. This resulted in the exit of certain programs within therapeutic areas. The R&D program exits were primarily in infectious diseases and vaccines including the discontinuation of its respiratory syncytial virus (RSV) adult vaccine program, hepatitis and HIV development. The restructuring expense of $102 million in fiscal 2024 included the termination of partnered and non-partnered program costs, asset impairments and asset divestments. This program was completed in Q4 2024.

In fiscal 2023, the company initiated a restructuring program of its Orthopaedics franchise within the MedTech segment to streamline operations by exiting certain markets, product lines and distribution network arrangements. The restructuring expense of $162 million in the fiscal fourth quarter of 2025 ($307 million Q4 2025 YTD) and $60 million in the fiscal fourth quarter of 2024 ($167 million Q4 2024 YTD) primarily includes costs related to market and product exits. This program was substantially completed in Q4 2025.

In fiscal 2025, the company initiated a restructuring program of its Surgery franchise within the MedTech segment to simplify and focus operations by exiting certain non-strategic product lines and optimize select sites across the network. The restructuring expense of $48 million in the fiscal fourth quarter of 2025 ($205 million Q4 2025 YTD) primarily includes costs related to asset impairments and market and product exits. This program is expected to be substantially completed by the end of fiscal year 2026.

<sup>2</sup>The tax impact related to special item adjustments reflects the current and deferred income taxes associated with the above pre-tax special items in arriving at adjusted earnings.

------

**Johnson & Johnson and subsidiaries**

**Reconciliation of non-GAAP financial measures**

**Adjusted operational sales growth**<sup>(A)</sup>

**Fourth quarter 2025 actual vs. 2024 actual**

---

| | | | |
|:---|:---|:---|:---|
| **Segments** | **Segments** | **Segments** | **Segments** |
| | **Innovative Medicine** | **MedTech** | **Total** |
| **WW As Reported** | **10.0%** | **7.5%** | **9.1%** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 7.9% | 6.6% | 7.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 13.4% | 8.5% | 11.3% |
| **WW Currency** | **2.1** | **1.7** | **2.0** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 5.5 | 3.6 | 4.7 |
| **WW Operational** | **7.9%** | **5.8%** | **7.1%** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 7.9% | 6.6% | 7.5% |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 7.9% | 4.9% | 6.6% |
| **Caplyta** | **(1.7)** |  | **(1.1)** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | (2.8) |  | (1.9) |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 0.0 |  | 0.0 |
| **All Other Acquisitions and Divestitures (A&D)** | **0.0** | **0.1** | **0.1** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 0.0 | 0.1 | 0.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 0.1 | 0.2 | 0.2 |
| **WW Adjusted Operational Ex A&D** | **6.2%** | **5.9%** | **6.1%** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 5.1% | 6.7% | 5.7% |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 8.0% | 5.1% | 6.8% |

---

**Note:** Percentages are based on actual, non-rounded figures and may not sum

<sup>(A)&nbsp;&nbsp;&nbsp;&nbsp;</sup>NON-GAAP FINANCIAL MEASURE "Adjusted operational sales growth" excludes acquisitions, divestitures and translational currency and is a non-GAAP financial measure. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP. Due to the variable nature of acquisitions and divestitures, and the impact they may have on the analysis of underlying business performance and trends, management believes that providing this measure enhances an investor's understanding of the Company's performance and may assist in the evaluation of ongoing business operations period over period. This non-GAAP financial measure is presented to permit investors to more fully understand how management assesses the performance of the Company, including for internal evaluation of the performance of the Company's businesses and planning and forecasting for future periods. The use of this non-GAAP financial measure as a performance measure is limited in that it provides a view of the Company's results of operations without including all events during a period and may not provide a comparable view of the Company's performance to that of other companies in the health care industry.

------

**Johnson & Johnson and subsidiaries**

**Reconciliation of non-GAAP financial measures**

**Adjusted operational sales growth**<sup>(A)</sup>

**Twelve months 2025 actual vs. 2024 actual**

---

| | | | |
|:---|:---|:---|:---|
| **Segments** | **Segments** | **Segments** | **Segments** |
| | **Innovative Medicine** | **MedTech** | **Total** |
| **WW As Reported** | **6.0%** | **6.1%** | **6.0%** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 7.0% | 6.6% | 6.9% |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 4.6% | 5.5% | 5.0% |
| **WW Currency** | **0.7** | **0.7** | **0.7** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 1.7 | 1.4 | 1.6 |
| **WW Operational** | **5.3%** | **5.4%** | **5.3%** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 7.0% | 6.6% | 6.9% |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 2.9% | 4.1% | 3.4% |
| **Shockwave** |  | **(1.4)** | **(0.5)** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. |  | (2.1) | (0.7) |
| &nbsp;&nbsp;&nbsp;&nbsp;International |  | (0.5) | (0.2) |
| **Caplyta** | **(1.2)** |  | **(0.7)** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | (2.1) |  | (1.4) |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 0.0 |  | 0.0 |
| **All Other Acquisitions and Divestitures (A&D)** | **0.0** | **0.3** | **0.1** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 0.0 | 0.3 | 0.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 0.1 | 0.2 | 0.1 |
| **WW Adjusted Operational Ex A&D** | **4.1%** | **4.3%** | **4.2%** |
| &nbsp;&nbsp;&nbsp;&nbsp;U.S. | 4.9% | 4.8% | 4.9% |
| &nbsp;&nbsp;&nbsp;&nbsp;International | 3.0% | 3.8% | 3.3% |

---

**Note:** Percentages are based on actual, non-rounded figures and may not sum

<sup>(A)&nbsp;&nbsp;&nbsp;&nbsp;</sup>NON-GAAP FINANCIAL MEASURE "Adjusted operational sales growth" excludes acquisitions, divestitures and translational currency and is a non-GAAP financial measure. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP. Due to the variable nature of acquisitions and divestitures, and the impact they may have on the analysis of underlying business performance and trends, management believes that providing this measure enhances an investor's understanding of the Company's performance and may assist in the evaluation of ongoing business operations period over period. This non-GAAP financial measure is presented to permit investors to more fully understand how management assesses the performance of the Company, including for internal evaluation of the performance of the Company's businesses and planning and forecasting for future periods. The use of this non-GAAP financial measure as a performance measure is limited in that it provides a view of the Company's results of operations without including all events during a period and may not provide a comparable view of the Company's performance to that of other companies in the health care industry.

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)</sup> |  |  |  |  |  |
| **ONCOLOGY** |  |  |  |  |  |
| US | **$3793** | **3019** | 25.6% | 25.6% | —% |
| Intl | **3069** | **2476** | 23.9 | 17.3 | 6.6 |
| WW | **6861** | **5497** | 24.8 | 21.9 | 2.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CARVYKTI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **420** | **304** | 38.2 | 38.2 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **135** | **31** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **555** | **334** | 65.8 | 63.2 | 2.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>DARZALEX</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **2332** | **1799** | 29.6 | 29.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1571** | **1285** | 22.3 | 16.2 | 6.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **3903** | **3084** | 26.6 | 24.1 | 2.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ERLEADA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **405** | **342** | 18.6 | 18.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **554** | **442** | 25.3 | 17.5 | 7.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **959** | **784** | 22.4 | 18.0 | 4.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>IMBRUVICA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **207** | **250** | (17.4) | (17.4) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **478** | **481** | (0.8) | (7.5) | 6.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **684** | **731** | (6.5) | (10.9) | 4.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>RYBREVANT / LAZCLUZE</u><sup>(3)</sup> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **146** | **101** | 45.6 | 45.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **70** | **21** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **216** | **122** | 78.0 | 76.5 | 1.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TALVEY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **105** | **68** | 53.8 | 53.8 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **44** | **17** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **149** | **85** | 75.8 | 73.1 | 2.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TECVAYLI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **110** | **108** | 2.7 | 2.7 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **66** | **38** | 72.2 | 65.1 | 7.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **176** | **146** | 20.8 | 18.9 | 1.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ZYTIGA / abiraterone acetate</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **5** | **9** | (41.4) | (41.4) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **115** | **127** | (9.9) | (11.1) | 1.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **119** | **135** | (11.9) | (13.0) | 1.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER ONCOLOGY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **61** | **39** | 54.8 | 54.8 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **39** | **36** | 8.4 | 3.0 | 5.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **100** | **75** | 32.9 | 30.3 | 2.6 |
| See footnotes at end of schedule |  |  |  |  |  |

---

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| **IMMUNOLOGY** |  |  |  |  |  |
| US | **$2495** | **2856** | (12.6)% | (12.6)% | —% |
| Intl | **1364** | **1383** | (1.4) | (5.5) | 4.1 |
| WW | **3860** | **4238** | (8.9) | (10.3) | 1.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>REMICADE</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **248** | **231** | 7.1 | 7.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US Exports<sup>(4)</sup> | **11** | **9** | 17.1 | 17.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **110** | **117** | (5.6) | (7.3) | 1.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **370** | **359** | 3.2 | 2.6 | 0.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SIMPONI / SIMPONI ARIA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **287** | **262** | 9.6 | 9.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **345** | **321** | 7.4 | 3.7 | 3.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **632** | **583** | 8.4 | 6.4 | 2.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>STELARA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **766** | **1699** | (54.9) | (54.9) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **462** | **650** | (28.8) | (32.3) | 3.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1230** | **2349** | (47.7) | (48.6) | 0.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TREMFYA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1145** | **654** | 75.1 | 75.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **445** | **295** | 50.9 | 44.0 | 6.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1589** | **949** | 67.6 | 65.4 | 2.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER IMMUNOLOGY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **39** | **0** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2** | **0** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **40** | **0** | \* | \* | \* |
| **NEUROSCIENCE** |  |  |  |  |  |
| US | **1439** | **1148** | 25.4 | 25.4 |  |
| Intl | **675** | **628** | 7.6 | 4.3 | 3.3 |
| WW | **2115** | **1775** | 19.1 | 17.9 | 1.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CAPLYTA</u><sup>(5)</sup> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **249** | **—** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **—** | **—** |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **249** | **—** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CONCERTA / methylphenidate</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **6** | **33** | (79.6) | (79.6) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **126** | **125** | (0.3) | (1.4) | 1.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **132** | **159** | (17.1) | (17.8) | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>INVEGA SUSTENNA / XEPLION / INVEGA<br>TRINZA / TREVICTA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **704** | **796** | (11.5) | (11.5) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **281** | **267** | 5.2 | 1.9 | 3.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **986** | **1063** | (7.3) | (8.2) | 0.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SPRAVATO</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **438** | **269** | 63.0 | 63.0 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **64** | **28** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **503** | **297** | 69.0 | 67.8 | 1.2 |
| See footnotes at end of schedule |  |  |  |  |  |

---

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER NEUROSCIENCE</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | $**40** | **49** | (18.3)% | (18.3)% | —% |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **205** | **206** | (0.7) | (4.3) | 3.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **245** | **255** | (4.1) | (6.9) | 2.8 |
| **PULMONARY HYPERTENSION** |  |  |  |  |  |
| US | **865** | **819** | 5.7 | 5.7 |  |
| Intl | **319** | **274** | 16.4 | 12.2 | 4.2 |
| WW | **1184** | **1092** | 8.4 | 7.4 | 1.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OPSUMIT / OPSYNVI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **458** | **408** | 11.9 | 11.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **185** | **162** | 14.8 | 10.9 | 3.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **643** | **570** | 12.7 | 11.6 | 1.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>UPTRAVI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **397** | **391** | 1.6 | 1.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **94** | **75** | 26.9 | 20.8 | 6.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **491** | **465** | 5.7 | 4.7 | 1.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER PULMONARY HYPERTENSION</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **10** | **19** | (43.7) | (43.7) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **39** | **38** | 2.6 | 1.2 | 1.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **49** | **57** | (12.5) | (13.5) | 1.0 |
| **INFECTIOUS DISEASES** |  |  |  |  |  |
| US | **303** | **331** | (8.5) | (8.5) |  |
| Intl | **505** | **443** | 13.9 | 5.6 | 8.3 |
| WW | **807** | **774** | 4.3 | (0.4) | 4.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>EDURANT / rilpivirine</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **5** | **7** | (39.1) | (39.1) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **379** | **315** | 20.6 | 11.1 | 9.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **383** | **322** | 19.2 | 9.9 | 9.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>PREZISTA / PREZCOBIX / REZOLSTA / SYMTUZA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **294** | **321** | (8.4) | (8.4) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **89** | **86** | 3.6 | (2.9) | 6.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **383** | **407** | (5.8) | (7.2) | 1.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER INFECTIOUS DISEASES</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **4** | **1** | 92.9 | 92.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **37** | **43** | (14.5) | (18.0) | 3.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **40** | **45** | (9.9) | (13.2) | 3.3 |
| See footnotes at end of schedule |  |  |  |  |  |

---

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| **CARDIOVASCULAR / METABOLISM / OTHER** |  |  |  |  |  |
| US | $**794** | **805** | (1.4)% | (1.4)% | —% |
| Intl | **142** | **153** | (6.3) | (10.7) | 4.4 |
| WW | **936** | **957** | (2.2) | (2.9) | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>XARELTO</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **687** | **676** | 1.7 | 1.7 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **—** | **—** |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **687** | **676** | 1.7 | 1.7 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **107** | **130** | (17.4) | (17.4) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **142** | **153** | (6.3) | (10.7) | 4.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **249** | **281** | (11.4) | (13.8) | 2.4 |
| **TOTAL INNOVATIVE MEDICINE** |  |  |  |  |  |
| **US** | **9689** | **8977** | **7.9** | **7.9** | **—** |
| **Intl** | **6074** | **5355** | **13.4** | **7.9** | **5.5** |
| **WW** | $**15763** | **14332** | **10.0%** | **7.9%** | **2.1%** |

---

See footnotes at end of schedule

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **MEDTECH SEGMENT**<sup>(2)</sup> |  |  |  |  |  |
| **CARDIOVASCULAR** |  |  |  |  |  |
| US | $**1374** | **1221** | 12.5% | 12.5% | —% |
| Intl | **925** | **841** | 10.1 | 6.8 | 3.3 |
| WW | **2299** | **2062** | 11.5 | 10.1 | 1.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ELECTROPHYSIOLOGY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **746** | **681** | 9.5 | 9.5 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **679** | **640** | 6.2 | 3.2 | 3.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1425** | **1321** | 7.9 | 6.5 | 1.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ABIOMED</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **358** | **308** | 16.5 | 16.5 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **102** | **77** | 33.1 | 25.4 | 7.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **460** | **384** | 19.8 | 18.3 | 1.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SHOCKWAVE</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **238** | **202** | 18.0 | 18.0 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **80** | **56** | 42.3 | 40.7 | 1.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **318** | **258** | 23.3 | 22.9 | 0.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER CARDIOVASCULAR</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **31** | **31** | (0.1) | (0.1) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **64** | **68** | (6.7) | (8.8) | 2.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **95** | **99** | (4.6) | (6.1) | 1.5 |
| **ORTHOPAEDICS** |  |  |  |  |  |
| US | **1520** | **1460** | 4.2 | 4.2 |  |
| Intl | **918** | **856** | 7.3 | 2.3 | 5.0 |
| WW | **2438** | **2315** | 5.3 | 3.5 | 1.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>HIPS</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **284** | **272** | 4.3 | 4.3 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **154** | **146** | 5.5 | 0.4 | 5.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **439** | **418** | 4.7 | 2.9 | 1.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>KNEES</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **251** | **238** | 5.1 | 5.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **181** | **160** | 13.7 | 9.2 | 4.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **432** | **398** | 8.6 | 6.8 | 1.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TRAUMA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **543** | **514** | 5.6 | 5.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **270** | **250** | 7.9 | 2.7 | 5.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **813** | **764** | 6.4 | 4.7 | 1.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SPINE, SPORTS & OTHER</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **442** | **434** | 1.9 | 1.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **312** | **300** | 4.2 | (0.7) | 4.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **756** | **735** | 2.8 | 0.8 | 2.0 |

---

See footnotes at end of schedule

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** | **FOURTH QUARTER** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **MEDTECH SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| **SURGERY** |  |  |  |  |  |
| US | **$1081** | **1038** | 4.2% | 4.2% | —% |
| Intl | **1563** | **1469** | 6.4 | 3.4 | 3.0 |
| WW | **2644** | **2507** | 5.5 | 3.7 | 1.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ADVANCED</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **489** | **478** | 2.5 | 2.5 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **687** | **673** | 1.9 | (0.8) | 2.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1175** | **1151** | 2.2 | 0.6 | 1.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>GENERAL</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **592** | **560** | 5.6 | 5.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **876** | **795** | 10.2 | 6.9 | 3.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1468** | **1357** | 8.3 | 6.3 | 2.0 |
| **VISION** |  |  |  |  |  |
| US | **531** | **509** | 4.3 | 4.3 |  |
| Intl | **889** | **794** | 11.9 | 8.5 | 3.4 |
| WW | **1420** | **1303** | 8.9 | 6.8 | 2.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CONTACT LENSES / OTHER</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **417** | **396** | 5.3 | 5.3 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **592** | **541** | 9.3 | 5.3 | 4.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1008** | **937** | 7.6 | 5.3 | 2.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SURGICAL</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **113** | **113** | 0.6 | 0.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **297** | **252** | 17.7 | 15.3 | 2.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **411** | **365** | 12.4 | 10.8 | 1.6 |
| **TOTAL MEDTECH** |  |  |  |  |  |
| **US** | **4506** | **4227** | **6.6** | **6.6** | **—** |
| **Intl** | **4295** | **3961** | **8.5** | **4.9** | **3.6** |
| **WW** | **$8801** | **8188** | **7.5%** | **5.8%** | **1.7%** |

---

See footnotes at end of schedule

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)</sup> |  |  |  |  |  |
| **ONCOLOGY** |  |  |  |  |  |
| US | **$13659** | **10854** | 25.8% | 25.8% | —% |
| Intl | **11721** | **9926** | 18.1 | 15.6 | 2.5 |
| WW | **25380** | **20781** | 22.1 | 20.9 | 1.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CARVYKTI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1492** | **869** | 71.6 | 71.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **395** | **94** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1887** | **963** | 95.9 | 94.3 | 1.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>DARZALEX</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **8266** | **6588** | 25.5 | 25.5 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **6085** | **5082** | 19.7 | 17.5 | 2.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **14351** | **11670** | 23.0 | 22.0 | 1.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ERLEADA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1453** | **1282** | 13.4 | 13.4 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2121** | **1717** | 23.5 | 20.1 | 3.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **3574** | **2999** | 19.2 | 17.2 | 2.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>IMBRUVICA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **892** | **1020** | (12.5) | (12.5) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1931** | **2018** | (4.3) | (6.7) | 2.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **2823** | **3038** | (7.1) | (8.6) | 1.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>RYBREVANT / LAZCLUZE</u><sup>(3)</sup> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **534** | **257** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **200** | **70** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **734** | **327** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TALVEY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **340** | **241** | 40.9 | 40.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **123** | **46** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **463** | **287** | 61.3 | 60.3 | 1.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TECVAYLI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **444** | **418** | 6.3 | 6.3 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **226** | **131** | 72.8 | 70.4 | 2.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **670** | **549** | 22.1 | 21.5 | 0.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ZYTIGA / abiraterone acetate</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **23** | **34** | (33.2) | (33.2) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **480** | **597** | (19.7) | (20.5) | 0.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **502** | **631** | (20.4) | (21.2) | 0.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER ONCOLOGY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **214** | **145** | 47.5 | 47.5 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **162** | **172** | (6.0) | (7.8) | 1.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **376** | **317** | 18.5 | 17.5 | 1.0 |
| See footnotes at end of schedule |  |  |  |  |  |

---

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| **IMMUNOLOGY** |  |  |  |  |  |
| US | **$9872** | **11355** | (13.1)% | (13.1)% | —% |
| Intl | **5856** | **6473** | (9.5) | (10.2) | 0.7 |
| WW | **15728** | **17828** | (11.8) | (12.0) | 0.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>REMICADE</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1171** | **1009** | 16.0 | 16.0 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US Exports<sup>(4)</sup> | **74** | **98** | (24.8) | (24.8) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **523** | **497** | 5.3 | 6.2 | (0.9) |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1768** | **1605** | 10.2 | 10.5 | (0.3) |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SIMPONI / SIMPONI ARIA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1193** | **1082** | 10.3 | 10.3 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1475** | **1108** | 33.1 | 32.8 | 0.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **2668** | **2190** | 21.8 | 21.7 | 0.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>STELARA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **3847** | **6720** | (42.7) | (42.7) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2230** | **3641** | (38.7) | (39.3) | 0.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **6078** | **10361** | (41.3) | (41.5) | 0.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TREMFYA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **3529** | **2443** | 44.5 | 44.5 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1626** | **1227** | 32.5 | 30.4 | 2.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **5155** | **3670** | 40.5 | 39.8 | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER IMMUNOLOGY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **59** | **3** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2** | **0** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **61** | **3** | \* | \* | \* |
| **NEUROSCIENCE** |  |  |  |  |  |
| US | **5151** | **4398** | 17.1 | 17.1 |  |
| Intl | **2686** | **2718** | (1.2) | (1.8) | 0.6 |
| WW | **7837** | **7115** | 10.1 | 9.9 | 0.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CAPLYTA</u><sup>(5)</sup> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **700** | **—** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **—** | **—** |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **700** | **—** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CONCERTA / methylphenidate</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **82** | **134** | (38.6) | (38.6) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **502** | **507** | (1.2) | (0.7) | (0.5) |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **584** | **641** | (9.0) | (8.6) | (0.4) |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>INVEGA SUSTENNA / XEPLION / INVEGA<br>TRINZA / TREVICTA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **2725** | **3125** | (12.8) | (12.8) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1085** | **1097** | (1.1) | (1.8) | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **3810** | **4222** | (9.8) | (9.9) | 0.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SPRAVATO</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1485** | **929** | 59.9 | 59.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **210** | **148** | 41.9 | 39.1 | 2.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1696** | **1077** | 57.4 | 57.0 | 0.4 |
| See footnotes at end of schedule |  |  |  |  |  |

---

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER NEUROSCIENCE</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | $**159** | **210** | (24.5)% | (24.5)% | —% |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **889** | **965** | (7.9) | (8.7) | 0.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1048** | **1175** | (10.9) | (11.5) | 0.6 |
| **PULMONARY HYPERTENSION** |  |  |  |  |  |
| US | **3223** | **3143** | 2.6 | 2.6 |  |
| Intl | **1214** | **1140** | 6.5 | 4.9 | 1.6 |
| WW | **4437** | **4282** | 3.6 | 3.2 | 0.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OPSUMIT / OPSYNVI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1633** | **1557** | 4.8 | 4.8 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **692** | **668** | 3.7 | 2.1 | 1.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **2325** | **2225** | 4.5 | 4.0 | 0.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>UPTRAVI</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1536** | **1511** | 1.7 | 1.7 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **366** | **307** | 19.4 | 17.4 | 2.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1902** | **1817** | 4.7 | 4.3 | 0.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER PULMONARY HYPERTENSION</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **54** | **75** | (27.0) | (27.0) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **155** | **165** | (6.2) | (6.8) | 0.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **209** | **240** | (12.7) | (13.0) | 0.3 |
| **INFECTIOUS DISEASES** |  |  |  |  |  |
| US | **1264** | **1354** | (6.6) | (6.6) |  |
| Intl | **1977** | **2042** | (3.2) | (6.5) | 3.3 |
| WW | **3241** | **3396** | (4.6) | (6.5) | 1.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>EDURANT / rilpivirine</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **26** | **31** | (18.4) | (18.4) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1461** | **1241** | 17.7 | 13.0 | 4.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1486** | **1272** | 16.9 | 12.2 | 4.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>PREZISTA / PREZCOBIX / REZOLSTA / SYMTUZA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1226** | **1311** | (6.5) | (6.5) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **353** | **401** | (11.9) | (13.7) | 1.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1579** | **1712** | (7.7) | (8.1) | 0.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER INFECTIOUS DISEASES</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **12** | **11** | 6.6 | 6.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **163** | **401** | (59.3) | (59.5) | 0.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **175** | **412** | (57.5) | (57.7) | 0.2 |
| See footnotes at end of schedule |  |  |  |  |  |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **INNOVATIVE MEDICINE SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| **CARDIOVASCULAR / METABOLISM / OTHER** |  |  |  |  |  |
| US | $**3175** | **2866** | 10.8% | 10.8% | —% |
| Intl | **603** | **696** | (13.3) | (13.8) | 0.5 |
| WW | **3778** | **3562** | 6.1 | 6.0 | 0.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>XARELTO</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **2633** | **2373** | 11.0 | 11.0 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **—** | **—** |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **2633** | **2373** | 11.0 | 11.0 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **542** | **494** | 9.8 | 9.8 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **603** | **696** | (13.3) | (13.8) | 0.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1145** | **1189** | (3.7) | (4.0) | 0.3 |
| **TOTAL INNOVATIVE MEDICINE** |  |  |  |  |  |
| **US** | **36344** | **33970** | **7.0** | **7.0** | **—** |
| **Intl** | **24057** | **22994** | **4.6** | **2.9** | **1.7** |
| **WW** | $**60401** | **56964** | **6.0%** | **5.3%** | **0.7%** |

---

See footnotes at end of schedule

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **MEDTECH SEGMENT**<sup>(2)</sup> |  |  |  |  |  |
| **CARDIOVASCULAR** |  |  |  |  |  |
| US | $**5305** | **4513** | 17.5% | 17.5% | —% |
| Intl | **3623** | **3194** | 13.4 | 11.9 | 1.5 |
| WW | **8928** | **7707** | 15.8 | 15.2 | 0.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ELECTROPHYSIOLOGY</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **2891** | **2738** | 5.6 | 5.6 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2743** | **2529** | 8.5 | 7.3 | 1.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **5634** | **5267** | 7.0 | 6.4 | 0.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ABIOMED</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1393** | **1213** | 14.9 | 14.9 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **358** | **284** | 26.4 | 22.0 | 4.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1751** | **1496** | 17.1 | 16.2 | 0.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SHOCKWAVE</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **897** | **442** | \* | \* |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **249** | **122** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1146** | **564** | \* | \* | \* |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>OTHER CARDIOVASCULAR</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **124** | **120** | 3.1 | 3.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **273** | **260** | 4.9 | 4.1 | 0.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **397** | **380** | 4.3 | 3.8 | 0.5 |
| **ORTHOPAEDICS** |  |  |  |  |  |
| US | **5720** | **5689** | 0.5 | 0.5 |  |
| Intl | **3538** | **3470** | 2.0 | (0.2) | 2.2 |
| WW | **9258** | **9158** | 1.1 | 0.3 | 0.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>HIPS</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1080** | **1057** | 2.1 | 2.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **594** | **581** | 2.2 | 0.1 | 2.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1674** | **1638** | 2.1 | 1.4 | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>KNEES</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **924** | **922** | 0.2 | 0.2 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **663** | **623** | 6.5 | 4.6 | 1.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1587** | **1545** | 2.7 | 2.0 | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>TRAUMA</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **2058** | **2013** | 2.2 | 2.2 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1088** | **1036** | 5.0 | 2.7 | 2.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **3146** | **3049** | 3.2 | 2.4 | 0.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SPINE, SPORTS & OTHER</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1658** | **1696** | (2.2) | (2.2) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1193** | **1230** | (3.0) | (5.3) | 2.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **2852** | **2926** | (2.5) | (3.5) | 1.0 |

---

See footnotes at end of schedule

------

**Johnson & Johnson**

**Segment sales**

**(Dollars in Millions)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** | **TWELVE MONTHS** |
| | | | **% Change** | **% Change** | **% Change** |
| | **2025** | **2024** | **Reported** | **Operational**<sup>(1)</sup> | **Currency** |
| **MEDTECH SEGMENT**<sup>(2)(Continued)</sup> |  |  |  |  |  |
| **SURGERY** |  |  |  |  |  |
| US | **$4157** | **4003** | 3.9% | 3.9% | —% |
| Intl | **5980** | **5842** | 2.4 | 1.5 | 0.9 |
| WW | **10137** | **9845** | 3.0 | 2.5 | 0.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>ADVANCED</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1900** | **1838** | 3.4 | 3.4 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2678** | **2650** | 1.0 | 0.1 | 0.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **4577** | **4488** | 2.0 | 1.5 | 0.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>GENERAL</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **2258** | **2165** | 4.3 | 4.3 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **3302** | **3192** | 3.4 | 2.7 | 0.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **5560** | **5358** | 3.8 | 3.3 | 0.5 |
| **VISION** |  |  |  |  |  |
| US | **2225** | **2128** | 4.6 | 4.6 |  |
| Intl | **3243** | **3018** | 7.4 | 5.9 | 1.5 |
| WW | **5468** | **5146** | 6.3 | 5.3 | 1.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>CONTACT LENSES / OTHER</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **1754** | **1684** | 4.1 | 4.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **2157** | **2049** | 5.3 | 3.2 | 2.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **3910** | **3733** | 4.8 | 3.6 | 1.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;<u>SURGICAL</u> |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;US | **471** | **444** | 6.1 | 6.1 |  |
| &nbsp;&nbsp;&nbsp;&nbsp;Intl | **1086** | **969** | 12.1 | 11.6 | 0.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;WW | **1558** | **1413** | 10.2 | 9.9 | 0.3 |
| **TOTAL MEDTECH** |  |  |  |  |  |
| **US** | **17408** | **16332** | **6.6** | **6.6** | **—** |
| **Intl** | **16384** | **15525** | **5.5** | **4.1** | **1.4** |
| **WW** | **$33792** | **31857** | **6.1%** | **5.4%** | **0.7%** |

---

**Note:** Column and rows within tables may not add due to rounding. Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

\*&nbsp;&nbsp;&nbsp;&nbsp;Percentage greater than 100% or not meaningful

<sup>(1)</sup> Operational growth excludes the effect of translational currency

<sup>(2)</sup> Unaudited

<sup>(3)</sup> Includes the sales of RYBREVANT and RYBREVANT + LAZCLUZE

<sup>(4)</sup> Reported as U.S. sales

<sup>(5)</sup> Acquired with Intra-Cellular Therapies on April 2, 2025

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