# EDGAR Filing Document

**Accession Number:** 0000859737
**File Stem:** 0001140361-25-028008
**Filing Date:** 2025-7
**Character Count:** 54203
**Document Hash:** 1cc871695b47c880814ca1cd37955354
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001140361-25-028008.hdr.sgml**: 20250730

**ACCESSION NUMBER**: 0001140361-25-028008

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 14

**CONFORMED PERIOD OF REPORT**: 20250730

**ITEM INFORMATION**: Results of Operations and Financial Condition

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20250730

**DATE AS OF CHANGE**: 20250730

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** HOLOGIC INC
- **CENTRAL INDEX KEY:** 0000859737
- **STANDARD INDUSTRIAL CLASSIFICATION:** X-RAY APPARATUS & TUBES & RELATED IRRADIATION APPARATUS [3844]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 042902449
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0928

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-36214
- **FILM NUMBER:** 251166890

**BUSINESS ADDRESS:**
- **STREET 1:** 250 CAMPUS DRIVE
- **CITY:** MARLBOROUGH
- **STATE:** MA
- **ZIP:** 01752
- **BUSINESS PHONE:** 5082632900

**MAIL ADDRESS:**
- **STREET 1:** 250 CAMPUS DRIVE
- **CITY:** MARLBOROUGH
- **STATE:** MA
- **ZIP:** 01752

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![graphic](image0.jpg)

### UNITED STATES

### SECURITIES AND EXCHANGE COMMISSION

#### Washington, D.C. 20549

### FORM 8-K

#### Current Report Pursuant

#### to Section 13 or 15(d) of the

#### Securities Exchange Act of 1934

#### Date of Report (Date of earliest event reported) July 30, 2025

## HOLOGIC, INC.

#### (Exact Name of Registrant as Specified in Its Charter)

#### DELAWARE

#### (State or Other Jurisdiction of Incorporation)

---

| | |
|:---|:---|
| **001-36214**<br>| **04-2902449**<br>|
| **(Commission File Number)** | **(I.R.S. Employer Identification No.)** |

---

---

| | |
|:---|:---|
| **250 Campus Drive, Marlborough, Massachusetts** | **01752**<br>|
| **(Address of Principal Executive Offices)** | **(Zip Code)** |

---

(508) 263-2900

#### (Registrant's Telephone Number, Including Area Code)

#### (Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

---

| | | |
|:---|:---|:---|
| **Title of each class** | **Trading Symbol(s)** | **Name of each exchange on which registered** |
| **Common Stock, $.01 par value**<br>| **HOLX**<br>| **The Nasdaq Stock Market LLC**<br>|

---

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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| | |
|:---|:---|
|  **Item 2.02** | **Results of Operations and Financial Condition.** |

---

On July 30, 2025, Hologic, Inc. issued a press release announcing its financial results for the third quarter ended June 28, 2025. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein in its entirety by reference.

***Limitation on Incorporation by Reference.*** The information furnished in this Item 2.02, including the press release attached hereto as Exhibit 99.1, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act except as set forth by specific reference in such a filing.

***Cautionary Note Regarding Forward-Looking Statements.*** Except for historical information contained in the press release attached as an exhibit hereto, the press release contains forward-looking statements that involve certain risks and uncertainties that could cause actual results to differ materially from those expressed or implied by these statements. Please refer to the cautionary note in the press release regarding these forward-looking statements.

---

| | |
|:---|:---|
|  **Item 9.01** | **Financial Statements and Exhibits.** |

---

(d) Exhibits.

---

| | |
|:---|:---|
| **Exhibit**<br> **Number** | **Description** |
| [99.1](ef20052949_ex99-1.htm) | Press release dated July 30, 2025, of Hologic, Inc. announcing its financial results for the third quarter ended June 28, 2025. |
| 104 | Cover Page Interactive Data File - the cover page XBRL tags are embedded within the Inline XBRL document. |

---

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#### SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

---

| | | |
|:---|:---|:---|
|  Date: July 30, 2025 | HOLOGIC, INC. | HOLOGIC, INC. |
|  | By: | <u>/s/ Karleen M. Oberton</u> |
|  |  | Karleen M. Oberton |
|  |  | Chief Financial Officer |

---

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## Exhibit 99.1

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#### Exhibit 99.1<br>

#### <br>

#### Hologic Announces Financial Results for Third Quarter of Fiscal 2025

– Revenue of $1,023.8 Million Exceeds Guidance –

– Company Reports GAAP Diluted EPS of $0.86; Non-GAAP Diluted EPS of $1.08 Exceeds Guidance –

– In Fourth Quarter, Company Remains on Track for Solid Revenue Growth and Faster Non-GAAP EPS Growth –

MARLBOROUGH, Mass. (July 30, 2025) – Hologic, Inc. (Nasdaq: HOLX) announced today the Company's financial results for the fiscal third quarter ended June 28, 2025*.*

"We are pleased to have delivered revenue and non-GAAP earnings growth in the third quarter that exceeded our guidance ranges," said Stephen P. MacMillan, the Company's Chairman, President and Chief Executive Officer. "And we made great progress toward returning to better top- and bottom-line growth in the fourth quarter, driven by the continued rebound of our Breast Health business and solid performances by our other divisions."

#### Recent Highlights
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Revenue of $1,023.8 million increased 1.2% for the quarter, or 0.4% in constant currency. This compares to the guidance range of $1,000 to $1,010 million that the Company provided
 in early May.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Total organic revenue excluding COVID-19, the divested blood screening and SSI businesses, and the acquired Endomagnetics and Gynesonics businesses decreased (0.8%), or (1.7%) on a
 constant currency basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• GAAP diluted EPS of $0.86 for the quarter increased 4.9%. Non-GAAP EPS of $1.08 increased 1.9% and exceeded the high-end of the guidance range of $1.04 to $1.07 that the Company
 provided in early May.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Diagnostics revenue of $448.9 million increased 1.8%, or 0.9% in constant currency, primarily driven by higher molecular diagnostics sales, partially offset by lower sales of
 COVID-19 assays.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Excluding COVID-19 revenue, organic diagnostics sales grew 3.9%, or 2.9% on a constant currency basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Molecular diagnostics revenue increased 3.2%, or 2.4% in constant currency, primarily driven by higher sales of the Company's BV CV/TV and Panther Fusion assays.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Excluding COVID-19 revenue, molecular diagnostics revenue grew 6.0%, or 5.2% on a constant currency basis. This included 7.3% growth in the United States.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Breast Health revenue of $365.2 million decreased (5.1%), or (5.8%) in constant currency, primarily driven by lower sales of mammography capital equipment, as expected. This
 decline was partially offset by the inclusion of Endomagnetics revenue and increased service contract revenue.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Organic breast health revenue, which excludes sales from the divested SSI and acquired Endomagnetics businesses, decreased (10.1%), or (10.8%) in constant currency.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Surgical revenue of $178.4 million grew 7.1%, or 6.3% in constant currency, primarily driven by the acquired Gynesonics business and strong international sales.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Organic surgical revenue, which excludes sales from Gynesonics, increased 2.0%, or 1.2% in constant currency.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Cash flow from operations was a strong $343.2 million in the third quarter.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The Company refinanced its term loan and revolving credit facility in July. The facility now comprises a $1.17 billion term loan and a $1.25 billion revolver, and matures in July
 2030.

------

Key financial results for the fiscal third quarter are shown in the table below.

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | GAAP | GAAP | GAAP | Non-GAAP | Non-GAAP | Non-GAAP |
|  | Q3'25 | Q3'24 | Change<br> *Increase (Decrease)* | Q3'25 | Q3'24 | Change<br> *Increase (Decrease)* |
|  Revenue | $1023.8 | $1011.4 | 1.2% | $1023.8 | $1011.4 | 1.2% |
|  Gross margin | 56.3% | 55.4% | 90 bps | 60.3% | 61.1% | (80 bps) |
|  Operating expenses | $322.0 | $316.3 | 1.8% | $309.6 | $302.8 | 2.2% |
|  Operating margin | 24.9% | 24.1% | 80 bps | 30.1% | 31.2% | (110 bps) |
|  Net margin | 19.0% | 19.2% | (20 bps) | 23.8% | 24.8% | (100 bps) |
|  Diluted EPS | $0.86 | $0.82 | 4.9% | $1.08 | $1.06 | 1.9% |

---

Throughout this press release, all dollar figures are in millions, except EPS, unless otherwise noted. Some totals may not foot due to rounding. Unless otherwise noted, all results are compared to the corresponding prior year period. Non-GAAP results exclude certain cash and non-cash items as discussed under "Use of Non-GAAP Financial Measures." Constant currency percentage changes show current period revenue results as if the foreign exchange rates were the same as those in the prior year period. Organic revenues for the fiscal third quarter exclude the divested blood screening and SSI ultrasound imaging businesses, as well as the acquired Endomagnetics (included in interventional breast solutions) and Gynesonics (included in GYN surgical) businesses. Revenue from acquired businesses is generally included in organic revenue starting a year after the acquisition.

#### Revenue Detail

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
|  |  |  | *Increase (Decrease)* | *Increase (Decrease)* | *Increase (Decrease)* | *Increase (Decrease)* | *Increase (Decrease)* |
| $ in millions | Q3'25 | Q3'24 | Global <br> Reported Change | Global<br> Constant Currency Change | U.S.<br> Reported Change | International<br> Reported<br> Change | International<br> Constant Currency Change |
|  Diagnostics |  |  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Cytology and perinatal | $121.4 | $122.2 | (0.7%) | (2.2%) | 3.4% | (6.8%) | (10.6%) |
| &nbsp;&nbsp;&nbsp; Molecular diagnostics | $320.5 | $310.7 | 3.2% | 2.4% | 3.6% | 1.2% | (2.2%) |
| &nbsp;&nbsp;&nbsp; Blood screening | $7.0 | $7.9 | (11.4%) | (11.4%) | (11.4%) | N/A | N/A |
|  Total diagnostics | $448.9 | $440.8 | 1.8% | 0.9% | 3.2% | (2.2%) | (5.8%) |
| &nbsp;&nbsp;&nbsp; *Organic diagnostics ex. COVID-19* | $410.4 | $394.9 | 3.9<br>*%* | 2.9<br>*%* | 6.3<br>*%* | *(2.6*<br>*%)* | *(6.3*<br>*%)* |
| &nbsp;&nbsp;&nbsp; *Organic molecular ex. COVID-19* | $289.0 | $272.7 | 6.0<br>*%* | 5.2<br>*%* | 7.3<br>*%* | 1.0<br>*%* | *(2.6*<br>*%)* |
|  Breast health |  |  |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp; Breast imaging | $264.7 | $309.2 | (14.4%) | (15.0%) | (15.0%) | (12.2%) | (14.8%) |
| &nbsp;&nbsp;&nbsp; Interventional breast solutions | $100.5 | $75.8 | 32.6% | 31.8% | 25.5% | 59.8% | 55.9% |
|  Total breast health | $365.2 | $385.0 | (5.1%) | (5.8%) | (6.9%) | 1.2% | (1.7%) |
| &nbsp;&nbsp;&nbsp; *Organic breast health* | $345.5 | $384.5 | *(10.1*<br>*%)* | *(10.8*<br>*%)* | *(10.8*<br>*%)* | *(7.9*<br>*%)* | *(10.8*<br>*%)* |
| &nbsp;&nbsp;&nbsp; *Organic interventional* | $81.0 | $75.8 | 6.9<br>*%* | 6.0<br>*%* | 6.2<br>*%* | 8.9<br>*%* | 5.0<br>*%* |
|  GYN surgical | $178.4 | $166.6 | 7.1% | 6.3% | 0.3% | 28.2% | 24.8% |
| &nbsp;&nbsp;&nbsp; *Organic surgical* | $169.9 | $166.6 | 2.0<br>*%* | 1.2<br>*%* | *(3.5*<br>*%)* | 19.3<br>*%* | 15.8<br>*%* |
|  Skeletal health | $31.3 | $19.0 | 64.7% | 62.1% | 42.0% | 108.0% | 100.2% |
|  Total | $1023.8 | $1011.4 | 1.2% | 0.4% | (0.6%) | 6.9% | 3.5% |
|  *Organic revenue (definition above)* | $988.6 | $*1003.0* | *(1.4*<br>*%)* | (2.3%) | *(2.7*<br>*%)* | 2.3<br>*%* | *(1.1*<br>*%)* |
|  *Organic revenue excluding COVID-19* | $957.1 | $965.0 | *(0.8*<br>*%)* | *(1.7*<br>*%)* | *(1.8*<br>*%)* | 2.3<br>*%* | *(1.1*<br>*%)* |

---

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#### Other Financial Highlights

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• U.S. revenue of $760.7 million decreased (0.6%). International revenue of $263.1 million increased 6.9%, or 3.5% in constant currency.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• GAAP gross margin of 56.3% increased 90 basis points primarily due to lower impairment charges. Non-GAAP gross margin of 60.3% decreased (80) basis points primarily due to product
 mix and increased reserves.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• GAAP operating margin of 24.9% increased 80 basis points primarily due to lower impairment charges. Non-GAAP operating margin of 30.1% decreased (110) basis points, primarily due
 to the expected margin dilution from the inclusion of Endomagnetics and Gynesonics results.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• GAAP net income of $194.9 million was flat to the prior year, while non-GAAP net income of $244.1 million decreased (2.6%). Adjusted earnings before interest, taxes, depreciation
 and amortization (EBITDA) were $340.9 million, an increase of 0.7%.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• COVID-19 revenue, which consisted of COVID-19 assay revenue of $6.5 million and other COVID-19 related revenue of $25.0 million, decreased (17.1%), or (17.8%) in constant currency.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The Company repurchased 0.7 million shares for $36 million in the third quarter of fiscal 2025.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• The Company ended the quarter with cash and cash equivalents of $1.74 billion and an adjusted net leverage ratio (net debt over adjusted EBITDA) of 0.6 times. In addition, the
 Company had short-term investments of $144 million.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;• Adjusted Return on Invested Capital (ROIC) was 13.9%, a decrease of (20) basis points compared to the prior year period.

#### Financial Guidance for the Fourth Quarter and Full Fiscal Year 2025

"Building on our solid third-quarter performance, in the fourth quarter we continue to expect mid-single-digit growth in organic, constant currency revenue excluding COVID," said Karleen Oberton, Hologic's Chief Financial Officer. "We also forecast non-GAAP earnings per share will grow faster than revenue, helped in part by our tariff mitigation efforts."

Hologic's financial guidance for the fourth quarter and full year 2025 is shown in the table below. The guidance is based on a full year non-GAAP tax rate of approximately 19.25%, and diluted shares outstanding of approximately 228 million for the full year. Constant currency guidance assumes that foreign exchange rates are the same in fiscal 2025 as in fiscal 2024. Organic revenue guidance for fiscal 2025 is in constant currency and excludes the divested blood screening and SSI ultrasound imaging businesses. Revenue from acquired businesses is generally included in organic revenue guidance starting a year after the acquisition. In fiscal 2025, revenue from the acquired Endomagnetics business becomes organic in August. Revenue from the acquired Gynesonics business will be excluded from organic revenue for all of fiscal 2025. Organic revenue excluding COVID-19 is in constant currency and is organic revenue excluding COVID-19 assay revenue and COVID-19 related revenue.

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  | Current Guidance | Current Guidance | Current Guidance | Current Guidance | Current Guidance | Previous <br> Guidance |
|  | Guidance $ | Reported %<br> Increase<br> (Decrease) | Constant <br> Currency %<br> Increase <br> (Decrease) | Organic %<br> Increase <br> (Decrease) | Organic<br> excluding <br> COVID-19 %<br> Increase<br> (Decrease) | Guidance $ |
|  <u>Fiscal 2025</u> |  |  |  |  |  |  |
|  Revenue | $4081 - $4091 | 1.3% to 1.5% | 1.1% to 1.4% | (0.5%) to (0.2%) | 0.6% to 0.8% | $4050 - $4100 |
|  GAAP EPS | $2.56 - $2.59 | (22.9%) to (22.0%) |  |  |  | $2.47 - $2.57 |
|  Non-GAAP EPS | $4.23 - $4.26 | 3.7% to 4.4% |  |  |  | $4.15 - $4.25 |
|  <u>Q4 2025</u> |  |  |  |  |  |  |
|  Revenue | $1030 - $1040 | 4.3% to 5.3% | 3.7% to 4.7% | 2.7% to 3.7% | 3.9% to 5.0% |  |
|  GAAP EPS | $0.90 - $0.93 | 18.4% to 22.4% |  |  |  |  |
|  Non-GAAP EPS | $1.09 - $1.12 | 7.9% to 10.9% |  |  |  |  |

---

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#### Use of Non-GAAP Financial Measures

The Company has presented the following non-GAAP financial measures in this press release: constant currency revenues; organic revenues; organic revenues excluding COVID-19; non-GAAP gross margin; non-GAAP operating expenses; non-GAAP operating margin; non-GAAP effective tax rate; non-GAAP net income; non-GAAP net income margin; non-GAAP EPS; adjusted EBITDA; adjusted net leverage ratio and adjusted ROIC. Organic revenue for the fiscal third quarter of 2025 excludes the divested Blood Screening and SSI ultrasound imaging businesses and the acquired Endomagnetics and Gynesonics businesses. Revenue from acquired businesses is generally included in organic revenue starting a year after the acquisition. Organic revenue excluding COVID-19 revenues is organic revenue less COVID-19 assay revenue, COVID-19 related sales of instruments, collection kits and ancillaries, COVID-19 related revenue from Diagenode and Mobidiag, as well as COVID-19 related license revenue, and revenues from discontinued products in Diagnostics. The Company defines its non-GAAP net income, EPS, and other non-GAAP financial measures to exclude, as applicable: (i) the amortization of intangible assets; (ii) the impairment of goodwill and intangible assets and equipment, and charges for the purchase of intellectual property to be used in a development project that has no future alternative use; (iii) adjustments to record contingent consideration at fair value; (iv) charges to write-off inventory for a product line discontinuance; (v) restructuring charges, facility closure and consolidation charges (including accelerated depreciation), and costs incurred to integrate acquisitions (including retention, contract termination costs, legal and professional consulting services); (vi) transaction related expenses for acquisitions; (vii) the step-up to fair value for acquired inventory sold; (viii) debt extinguishment losses and related transaction costs; (ix) the unrealized (gains) losses on the mark-to-market of foreign currency contracts to hedge operating results for which the Company has not elected hedge accounting; (x) litigation settlement charges (benefits) and non-income tax related charges (benefits); (xi) other-than-temporary impairment losses on investments and realized gains and losses resulting from the sale of investments; (xii) the one-time discrete impacts related to internal restructurings and non-operational items; (xiii) other one-time, non-recurring, unusual or infrequent charges, expenses or gains that may not be indicative of the Company's core business results; and (xiv) income taxes related to such adjustments. The Company defines adjusted EBITDA as its non-GAAP net income plus net interest income/expense, income taxes, and depreciation and amortization expense included in its non-GAAP net income. The Company defines its adjusted net leverage ratio as the principal amount of its debt net of cash and cash equivalents, divided by its adjusted EBITDA for the last four quarters. The Company defines its adjusted ROIC as its non-GAAP operating income for a trailing twelve months tax effected by its non-GAAP effective tax rate divided by the sum of its average net debt and stockholders' equity, which is adjusted to exclude the after-tax effects of goodwill and intangible assets and equipment impairment charges.

These non-GAAP financial measures should be considered supplemental to, and not a substitute for, financial information prepared in accordance with GAAP. The Company's definition of these non-GAAP measures may differ from similarly titled measures used by others.

The non-GAAP financial measures used in this press release adjust for specified items many of which can be highly variable or difficult to predict. The Company generally uses these non-GAAP financial measures to facilitate management's financial and operational decision-making, including evaluation of Hologic's historical operating results, comparison to competitors' operating results and determination of management incentive compensation. These non-GAAP financial measures reflect an additional way of viewing aspects of the Company's operations that, when viewed with GAAP results and the reconciliations to corresponding GAAP financial measures, may provide a more complete understanding of factors and trends affecting Hologic's business.

Because non-GAAP financial measures exclude the effect of items that will increase or decrease the Company's reported results of operations, management strongly encourages investors to review the Company's consolidated financial statements and publicly filed reports in their entirety. A reconciliation of the non-GAAP financial measures to the most directly comparable GAAP financial measures is included in the tables accompanying this release.

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#### Conference Call and Webcast

Hologic's management will host a conference call at 4:30 p.m. ET today to discuss its financial results for the third quarter of fiscal 2025. Interested participants may listen to the call by dialing (866) 400-0049 (in the U.S. and Canada) or +1 (313) 209-4906 (for international callers) and referencing access code 5212316. Participants may also <u>click here to join</u>. Participants should dial in 5-10 minutes before the call begins. The Company will also provide a live and replay webcast of the call at <u>hologic.com/investors</u>. The replay of the call will be available approximately two hours after the call ends through Friday, August 29, 2025.

#### About Hologic, Inc.

Hologic, Inc. is an innovative medical technology company primarily focused on improving women's health and well-being through early detection and treatment. For more information on Hologic, visit <u>www.hologic.com</u>.

Hologic and associated logos are trademarks and/or registered trademarks of Hologic, Inc. and/or its subsidiaries in the United States and/or other countries.

#### Forward-Looking Statements

This news release contains forward-looking information that involves risks and uncertainties, including statements about the Company's plans, objectives, expectations and intentions. Such statements include, without limitation: financial or other information based upon or otherwise incorporating judgments or estimates relating to future performance, events or expectations; the Company's strategies, positioning, resources, capabilities, and expectations for future performance; and the Company's outlook and financial and other guidance. These forward-looking statements are based upon assumptions made by the Company as of the date hereof and are subject to known and unknown risks and uncertainties that could cause actual results to differ materially from those anticipated.

Risks and uncertainties that could adversely affect the Company's business and prospects, and otherwise cause actual results to differ materially from those anticipated, include, without limitation: the development of new or improved competitive technologies and products and competition; the anticipated development of markets the Company sells its products into and the success of the Company's products in these markets; the Company's ability to predict accurately the demand for its products, and products under development and to develop strategies to address markets successfully; the anticipated performance and benefits of the Company's products; the Company's business strategies; the effect of consolidation in the healthcare industry; the ability to execute acquisitions and the impact and anticipated benefits of completed acquisitions and acquisitions the Company may complete in the future; the coverage and reimbursement decisions of third-party payors; the uncertainty of the impact of cost containment efforts and federal healthcare reform legislation on our business and results of operations; the guidelines, recommendations, and studies published by various organizations relating to the use of the Company's products; the Company's ability to obtain and maintain regulatory approvals and clearances for its products, including the implementation of the European Union Medical Device and In Vitro Diagnostic Regulation requirements, and maintain compliance with complex and evolving regulations and quality standards, as well as the uncertainty of costs required to obtain and maintain compliance with such regulatory and quality matters; the possibility that products may contain undetected errors or defects or otherwise not perform as anticipated; the impact and costs and expenses of investigative and legal proceedings and compliance risks the Company may be subject to now or in the future; potential negative impacts resulting from climate change or other environmental, social, and governance and sustainability related matters; the impact of future tax legislation; the ongoing and possible future effects of global challenges, including macroeconomic uncertainties, such as inflation, bank failures, rising interest rates and availability of capital markets, wars, conflicts, other economic disruptions and U.S. and global recession concerns, on the Company's customers and suppliers and on the Company's business, financial condition, results of operations and cash flows and the Company's ability to draw down its revolver; the effect of the worldwide political and social uncertainty and divisions, including the impact on trade regulations and tariffs, that may adversely impact the cost and sale of the Company's products in certain countries, or increase the costs the Company may incur to purchase materials, parts and equipment from its suppliers; conducting business internationally; potential cybersecurity threats and targeted computer crime; the ongoing and possible future effects of supply chain constraints, including the availability of critical raw materials and components, as well as cost inflation in materials, packaging and transportation; the possibility of interruptions or delays at the Company's manufacturing facilities, or the failure to secure alternative suppliers if any of the Company's sole source third-party manufacturers fail to supply the Company; the ability to consolidate certain of the Company's manufacturing and other operations on a timely basis and within budget, without disrupting the Company's business and to achieve anticipated cost synergies related to such actions; the Company's ability to meet production and delivery schedules for its products; the effect of any future public health pandemic or other crises, including the timing, scope and effect of U.S. and international governmental, regulatory, fiscal, monetary and public health responses to such crises; the ability to successfully manage ongoing organizational and strategic changes, including the Company's ability to attract, motivate and retain key employees and maintain engagement and efficiency in remote work environments; the Company's ability to protect its intellectual property rights; anticipated trends relating to the Company's financial condition or results of operations, including the impact of interest rate and foreign currency exchange fluctuations; estimated asset and liability values; compliance with covenants contained in the Company's debt agreements; and the Company's liquidity, capital resources and the adequacy thereof.

------

The risks included above are not exhaustive. Other factors that could adversely affect the Company's business and prospects are described in the filings made by the Company with the SEC, including its most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q. The Company expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any such statements presented herein to reflect any change in expectations or any change in events, conditions or circumstances on which any such statements are based.

#### Contacts:

#### Michael Watts
Corporate Vice President, Investor Relations

<u>Michael.Watts@hologic.com</u>

(858) 410-8514

#### Peter Sattler
Senior Manager, Investor Relations

<u>Peter.Sattler@hologic.com</u>

(858) 410-8423

SOURCE: Hologic, Inc.

------

HOLOGIC, INC.

CONDENSED CONSOLIDATED STATEMENTS OF INCOME

(Unaudited)

(In millions, except number of shares, which are reflected in thousands, and per share data)

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months Ended** | **Three Months Ended** | **Nine Months Ended** | **Nine Months Ended** |
|  | **June 28, 2025** | **June 29, 2024** | **June 28, 2025** | **June 29, 2024** |
|  **Revenues**: | | | | |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Product | $810.4 | $811.2 | $2421.0 | $2467.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Service and other | 213.4 | 200.2 | 629.9 | 575.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total revenues | 1023.8 | 1011.4 | 3050.9 | 3042.3 |
|  **Cost of revenues:** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Product | 310.5 | 298.2 | 916.6 | 913.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets | 41.1 | 44.4 | 135.3 | 134.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Impairment of intangible assets |  | 13.3 | 183.4 | 39.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Service and other | 95.6 | 95.2 | 281.2 | 284.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; **Gross profit** | 576.6 | 560.3 | 1534.4 | 1670.1 |
|  **Operating expenses:** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Research and development | 61.4 | 64.1 | 183.1 | 205.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Selling and marketing | 152.2 | 146.3 | 472.8 | 439.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; General and administrative | 99.1 | 94.0 | 334.5 | 306.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets | 3.0 | 5.3 | 11.5 | 24.3 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Impairment of intangible assets |  | 0.4 | 37.5 | 5.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Contingent consideration fair value adjustment |  |  |  | 1.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Restructuring charges | 6.3 | 6.2 | 17.6 | 34.8 |
| &nbsp;&nbsp;&nbsp; Total operating expenses | 322.0 | 316.3 | 1057.0 | 1017.5 |
|  **Income from operations** | 254.6 | 244.0 | 477.4 | 652.6 |
|  Interest income | 16.4 | 28.4 | 55.5 | 80.3 |
|  Interest expense | (28.9) | (31.9) | (88.5) | (90.2) |
|  Other income (expense), net | (7.1) | 0.2 | 9.6 | 0.8 |
|  **Income before income taxes** | 235.0 | 240.7 | 454.0 | 643.5 |
|  Provision for income taxes | 40.1 | 46.2 | 75.5 | 32.6 |
|  **Net income** | $194.9 | $194.5 | $378.5 | $610.9 |
|  **Net income per common share:** |  |  |  |  |
|  Basic | $0.87 | $0.83 | $1.67 | $2.58 |
|  Diluted | $0.86 | $0.82 | $1.66 | $2.57 |
|  **Weighted average number of shares outstanding:** |  |  |  |  |
|  Basic | 224315 | 234604 | 226791 | 236373 |
|  Diluted | 225462 | 236466 | 228186 | 238081 |

---

------

HOLOGIC, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS

(Unaudited)

(In millions)

---

| | | |
|:---|:---|:---|
|  | **June 28, 2025** | **September 28, 2024** |
|  **ASSETS** | | |
|  **Current assets:** | | |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Cash and cash equivalents | $1735.2 | $2160.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Short-term investments | 143.9 | 173.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Accounts receivable, net | 609.3 | 600.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Inventory | 713.7 | 679.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Other current assets | 219.3 | 209.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total current assets | 3421.4 | 3823.3 |
|  Property, plant and equipment, net | 570.5 | 537.8 |
|  Goodwill and intangible assets | 4286.1 | 4287.7 |
|  Long-term investments |  | 96.4 |
|  Other assets | 528.1 | 410.8 |
|  **Total assets** | $8806.1 | $9156.0 |
|  **LIABILITIES AND STOCKHOLDERS' EQUITY** |  |  |
|  **Current liabilities**: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Current portion of long-term debt | $— | $37.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Accounts payable and accrued liabilities | 749.8 | 786.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Deferred revenue | 212.7 | 212.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Total current liabilities | 962.5 | 1037.2 |
|  Long-term debt, net of current portion | 2509.0 | 2497.1 |
|  Deferred income taxes | 46.6 | 59.4 |
|  Other long-term liabilities | 445.5 | 432.3 |
| &nbsp;&nbsp;&nbsp; Total stockholders' equity | 4842.5 | 5130.0 |
|  **Total liabilities and stockholders' equity** | $8806.1 | $9156.0 |

---

------

HOLOGIC, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(Unaudited)

(In millions)

---

| | | |
|:---|:---|:---|
|  | **Nine Months Ended** | **Nine Months Ended** |
|  | **June 28, 2025** | **June 29, 2024** |
|  OPERATING ACTIVITIES |  |  |
|  Net income | $378.5 | $610.9 |
|  Adjustments to reconcile net income to net cash provided by operating activities: |  |  |
| &nbsp;&nbsp;&nbsp; Depreciation | 73.5 | 75.2 |
| &nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets | 146.8 | 159.2 |
| &nbsp;&nbsp;&nbsp; Stock-based compensation expense | 72.0 | 69.1 |
| &nbsp;&nbsp;&nbsp; Deferred income taxes | (111.3) | (52.3) |
| &nbsp;&nbsp;&nbsp; Intangible asset impairment charges | 220.9 | 44.8 |
| &nbsp;&nbsp;&nbsp; Other adjustments and non-cash items | 15.0 | 34.1 |
| &nbsp;&nbsp;&nbsp; Changes in operating assets and liabilities, excluding the effect of acquisitions and dispositions: |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Accounts receivable | 3.2 | (2.5) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Inventories | (34.7) | (47.1) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Prepaid income taxes | (1.7) | (73.9) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Prepaid expenses and other assets | 16.7 | (4.2) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Accounts payable | (12.4) | 26.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Accrued expenses and other liabilities | (61.4) | 58.5 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Deferred revenue | (3.1) | 19.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Net cash provided by operating activities | 702.0 | 918.2 |
|  INVESTING ACTIVITIES |  |  |
| &nbsp;&nbsp;&nbsp; Acquisition of business, net of cash acquired | (321.5) |  |
| &nbsp;&nbsp;&nbsp; Sale of business, net of cash disposed |  | (31.3) |
| &nbsp;&nbsp;&nbsp; Capital expenditures | (45.1) | (56.0) |
| &nbsp;&nbsp;&nbsp; Increase in equipment under customer usage agreements | (61.5) | (43.9) |
| &nbsp;&nbsp;&nbsp; Strategic investments | (33.0) | (42.5) |
| &nbsp;&nbsp;&nbsp; Purchase of intellectual property | (15.4) | (10.0) |
| &nbsp;&nbsp;&nbsp; Maturities of available-for-sale securities | 128.0 |  |
| &nbsp;&nbsp;&nbsp; Other activity | (2.1) | (1.6) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Net cash used in investing activities | (350.6) | (185.3) |
|  FINANCING ACTIVITIES |  |  |
| &nbsp;&nbsp;&nbsp; Repayment of long-term debt | (28.1) | (278.1) |
| &nbsp;&nbsp;&nbsp; Payment of contingent consideration | (1.1) | (2.6) |
| &nbsp;&nbsp;&nbsp; Repurchases of common stock | (752.9) | (776.8) |
| &nbsp;&nbsp;&nbsp; Proceeds under employee stock plans | 27.7 | 25.2 |
| &nbsp;&nbsp;&nbsp; Payment of minimum tax withholdings on net share settlements of equity awards | (22.0) | (16.6) |
| &nbsp;&nbsp;&nbsp; Payments under finance lease obligations | (2.4) | (2.9) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Net cash used in financing activities | (778.8) | (1051.8) |
|  Effect of exchange rate changes on cash and cash equivalents | 2.4 | 2.3 |
|  Net decrease in cash and cash equivalents | (425.0) | (316.6) |
|  Cash and cash equivalents, beginning of period\* | 2160.2 | 2755.7 |
|  Cash and cash equivalents, end of period | $1735.2 | $2439.1 |

---

\*Includes $33.2 million of cash recorded in assets held-for-sale - current assets as of September 30, 2023.

------

HOLOGIC, INC.

RECONCILIATION OF GAAP TO NON-GAAP RESULTS

(Unaudited)

(In millions, except earnings per share)

#### Reconciliation of GAAP Revenue to Organic Revenue

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months Ended** | **Three Months Ended** | **Nine Months Ended** | **Nine Months Ended** |
|  | **June 28, 2025** | **June 29, 2024** | **June 28, 2025** | **June 29, 2024** |
|  **Consolidated GAAP Revenue** | $1023.8 | $1011.4 | $3050.9 | $3042.3 |
| &nbsp;&nbsp;&nbsp; Less: Blood Screening revenue | (7.0) | (7.9) | (20.3) | (22.8) |
| &nbsp;&nbsp;&nbsp; Less: SSI revenue | (0.1) | (0.5) | (0.7) | (2.3) |
| &nbsp;&nbsp;&nbsp; Less: Endomagnetics revenue | (19.6) |  | (43.4) |  |
| &nbsp;&nbsp;&nbsp; Less: Gynesonics revenue | (8.5) |  | (14.7) |  |
|  **Organic Revenue** | $988.6 | $1003.0 | $2971.8 | $3017.2 |
| &nbsp;&nbsp;&nbsp; Less: COVID-19 Assays | (6.5) | (13.3) | (33.9) | (63.4) |
| &nbsp;&nbsp;&nbsp; Less: COVID-19 Related Revenue\* | (25.0) | (24.7) | (78.3) | (79.5) |
|  **Organic Revenue excluding COVID-19** | $957.1 | $965.0 | $2859.6 | $2874.3 |

---

\*Revenues estimated to be related to COVID assay sales for instruments, collection kits and ancillaries.

------

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months Ended** | **Three Months Ended** | **Nine Months Ended** | **Nine Months Ended** |
|  | **June 28, 2025** | **June 29, 2024** | **June 28, 2025** | **June 29, 2024** |
|  **Gross Profit:** | | | | |
|  GAAP gross profit | $576.6 | $560.3 | $1534.4 | $1670.1 |
| &nbsp;&nbsp;&nbsp; Adjustments: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets (1) | 41.1 | 44.4 | 135.3 | 134.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Impairment of intangible assets (13) |  | 13.3 | 183.4 | 39.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Product line discontinuance (12) |  |  |  | 7.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Acquisition related expenses (2) (4) |  |  | 8.9 |  |
|  Non-GAAP gross profit | $617.7 | $618.0 | $1862.0 | $1851.3 |
|  **Gross Margin Percentage:** |  |  |  |  |
|  GAAP gross margin percentage | 56.3% | 55.4% | 50.3% | 54.9% |
| &nbsp;&nbsp;&nbsp; Impact of adjustments above | 4.0% | 5.7% | 10.7% | 6.0% |
|  Non-GAAP gross margin percentage | 60.3% | 61.1% | 61.0% | 60.9% |
|  **Operating Expenses:** |  |  |  |  |
|  GAAP operating expenses | $322.0 | $316.3 | $1057.0 | $1017.5 |
| &nbsp;&nbsp;&nbsp; Adjustments: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets (1) | (3.0) | (5.3) | (11.5) | (24.3) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Impairment of intangible assets (13) |  | (0.4) | (37.5) | (5.6) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Acquisition related expenses (4) (15) | (2.3) | (1.6) | (27.8) | (3.4) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Contingent consideration adjustment (7) |  |  |  | (1.7) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Integration/consolidation costs (3) | (0.8) |  | (11.0) |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Purchased research and development asset charge (14) |  |  |  | (10.0) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Restructuring charges (3) | (6.3) | (6.2) | (17.6) | (34.8) |
|  Non-GAAP operating expenses | $309.6 | $302.8 | $951.6 | $937.7 |
|  **Operating Margin:** |  |  |  |  |
|  GAAP income from operations | $254.6 | $244.0 | $477.4 | $652.6 |
| &nbsp;&nbsp;&nbsp; Adjustments to gross profit as detailed above | 41.1 | 57.7 | 327.6 | 181.2 |
| &nbsp;&nbsp;&nbsp; Adjustments to operating expenses as detailed above | 12.4 | 13.5 | 105.4 | 79.8 |
|  Non-GAAP income from operations | $308.1 | $315.2 | $910.4 | $913.6 |
|  **Operating Margin Percentage:** |  |  |  |  |
|  GAAP income from operations margin percentage | 24.9% | 24.1% | 15.6% | 21.5% |
| &nbsp;&nbsp;&nbsp; Impact of adjustments above | 5.2% | 7.1% | 14.2% | 8.5% |
|  Non-GAAP operating margin percentage | 30.1% | 31.2% | 29.8% | 30.0% |

---

------

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months Ended** | **Three Months Ended** | **Nine Months Ended** | **Nine Months Ended** |
|  | **June 28, 2025** | **June 29, 2024** | **June 28, 2025** | **June 29, 2024** |
|  **Pre-Tax Income:** | | | | |
|  GAAP pre-tax earnings | $235.0 | $240.7 | $454.0 | $643.5 |
| &nbsp;&nbsp;&nbsp; Adjustments to pre-tax earnings as detailed above | 53.5 | 71.2 | 433.0 | 261.0 |
| &nbsp;&nbsp;&nbsp; Debt extinguishment loss (6) |  |  |  | 0.4 |
| &nbsp;&nbsp;&nbsp; Unrealized losses (gains) on forward foreign currency contracts (8) | 13.8 | 0.5 | (0.8) | 6.2 |
|  Non-GAAP pre-tax income | $302.3 | $312.4 | $886.2 | $911.1 |
|  **Net Income:** |  |  |  |  |
|  GAAP net income | $194.9 | $194.5 | $378.5 | $610.9 |
| &nbsp;&nbsp;&nbsp; Adjustments: |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets (1) | 44.1 | 49.7 | 146.8 | 159.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Impairment of intangible assets (13) |  | 13.7 | 220.9 | 44.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Restructuring and integration/consolidation costs (3) | 7.1 | 6.2 | 28.6 | 34.8 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Purchased research and development asset charge (14) |  |  |  | 10.0 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Product line discontinuance (12) |  |  |  | 7.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Debt extinguishment loss (6) |  |  |  | 0.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Acquisition related expenses (2) (4) (15) | 2.3 | 1.6 | 36.7 | 3.4 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Contingent consideration adjustment (7) |  |  |  | 1.7 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Unrealized losses (gains) on forward foreign currency contracts (8) | 13.8 | 0.5 | (0.8) | 6.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Worthless stock deduction (5) |  |  |  | (107.2) |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Income tax related items (9) | (3.1) | 3.7 | 6.5 | 15.6 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Income tax effect of reconciling items (11) | (15.0) | (19.2) | (101.6) | (55.7) |
|  Non-GAAP net income | $244.1 | $250.7 | $715.6 | $731.2 |
|  **Net Income Percentage:** |  |  |  |  |
|  GAAP net income percentage | 19.0% | 19.2% | 12.4% | 20.1% |
| &nbsp;&nbsp;&nbsp; Impact of adjustments above | 4.8% | 5.6% | 11.1% | 3.9% |
| &nbsp;&nbsp;&nbsp; Non-GAAP net income percentage | 23.8% | 24.8% | 23.5% | 24.0% |
|  **Earnings per Share:** |  |  |  |  |
|  GAAP income per share - Diluted | $0.86 | $0.82 | $1.66 | $2.57 |
| &nbsp;&nbsp;&nbsp; Adjustment to net income (as detailed above) | 0.22 | 0.24 | 1.48 | 0.50 |
|  Non-GAAP earnings per share – diluted (10) | $1.08 | $1.06 | $3.14 | $3.07 |
|  **Adjusted EBITDA:** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Non-GAAP net income | $244.1 | $250.7 | $715.6 | $731.2 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Interest expense (income), net | 12.5 | 3.5 | 33.0 | 9.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Provision for income taxes | 58.2 | 61.7 | 170.6 | 179.9 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Depreciation expense, not adjusted above | 26.1 | 22.6 | 73.5 | 68.0 |
|  Adjusted EBITDA | $340.9 | $338.5 | $992.7 | $989.0 |

---

------

#### Explanatory Notes to Reconciliations:
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) To reflect non-cash expenses attributable to the amortization of acquired intangible assets.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) To reflect the fair value write-up of inventory sold during the period related to the Endomagnetics and Gynesonics acquisitions of $3.3 million and $4.0
 million in the first and second quarters of fiscal 2025, respectively.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) To reflect restructuring charges, and certain costs associated with the Company's integration and facility consolidation plans, which primarily include
 severance, retention, and transfer costs as well as costs incurred to integrate acquisitions, including legal, tax and professional consulting services and contract termination costs.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4) To reflect expenses with third parties related to acquisitions prior to when such transactions are completed. These expenses primarily comprise legal,
 consulting and due diligence fees.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5) To reflect the discrete tax benefit related to a worthless stock deduction on the investment in one of the Company's international subsidiaries.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(6) To reflect a debt extinguishment loss for the prepayment of principal under the Credit Agreement in first quarter of fiscal 2024.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(7) To reflect an adjustment to the estimated contingent consideration liability related to the Acessa Health acquisition, which was payable upon meeting defined revenue growth
 metrics.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(8) To reflect non-cash unrealized gains and losses on the mark-to market on outstanding forward foreign currency contracts, for which the Company has elected to
 not designate for hedge accounting.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(9) To reflect the net impact of income tax reserves from the expiration of the statute of limitations, and non-recurring income tax charges and benefits.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(10) Non-GAAP earnings per share was calculated based on 225,462 and 228,186 weighted average diluted shares outstanding for the three and nine months ended June
 28, 2025, respectively, and 236,466 and 238,081 for the three and nine months ended June 29, 2024, respectively.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(11) To reflect the tax effects of Non-GAAP reconciling items, excluding specific income tax related items and the worthless stock deduction. Amounts are
 calculated using the effective tax rate in the jurisdiction to which the adjustment relates, and the overall effective tax rate was 19.25% for the three and nine months ended June 28, 2025, and 19.75% for the three and nine months ended
 June 29, 2024.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(12) To reflect the write-off of inventory and charges for non-cancellable purchase orders related to a product line discontinuance in the Diagnostics division.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(13) To reflect impairment charges related to the Acessa ($61.9 million), Bolder ($64.5 million), Mobidiag ($39.0 million), and Diagenode ($38.6 million)
 acquisitions recorded during the second quarter of fiscal 2025 and impairment charges related to BioZorb of $26.8 million and $13.7 million recorded during the second and third quarters, respectively, of fiscal 2024. In addition, an
 impairment charge for an in-process research and development intangible asset acquired in the Mobidiag acquisition was recorded during the second quarters of fiscal 2024 ($4.3 million) and 2025 ($16.9 million).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(14) To reflect the purchase of an intangible asset to be used in a research and development project that has no future alternative use.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(15) To reflect an aggregate charge of $22.4 million for the acceleration of unvested stock options in connection with the Gynesonics acquisition recorded in the
 second quarter of fiscal 2025.

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#### Reconciliation of GAAP to non-GAAP EPS Guidance:

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| | | | | |
|:---|:---|:---|:---|:---|
|  | Guidance Range | Guidance Range | Guidance Range | Guidance Range |
|  | Quarter Ending<br> September 27, 2025 | Quarter Ending<br> September 27, 2025 | Year Ending<br> September 27, 2025 | Year Ending<br> September 27, 2025 |
|  | <u>Low</u> | <u>High</u> | <u>Low</u> | <u>High</u> |
|  <u>GAAP Net Income Per Share</u> | $0.90 | $0.93 | $2.56 | $2.59 |
| &nbsp;&nbsp;&nbsp; Amortization of acquired intangible assets | $0.21 | $0.21 | $0.85 | $0.85 |
| &nbsp;&nbsp;&nbsp; Impairment of intangible assets | $- | $- | $0.97 | $0.97 |
| &nbsp;&nbsp;&nbsp; Acquisition Related | $- | $- | $0.20 | $0.20 |
| &nbsp;&nbsp;&nbsp; Restructuring, Integration and Other charges | $0.02 | $0.02 | $0.10 | $0.10 |
| &nbsp;&nbsp;&nbsp; Income tax related items | $- | $- | $0.03 | $0.03 |
| &nbsp;&nbsp;&nbsp; Tax Impact of Exclusions | $(0.04) | $(0.04) | $(0.48) | $(0.48) |
|  Non-GAAP Net Income Per Share | $1.09 | $1.12 | $4.23 | $4.26 |

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| | |
|:---|:---|
| **Adjusted Return on Invested Capital (ROIC) Reconciliation of Net Income to ROIC:** | **Adjusted Return on Invested Capital (ROIC) Reconciliation of Net Income to ROIC:** |
|  | **Trailing Twelve** <br> **Months Ended June** <br> **28, 2025** |
|  **Adjusted Net Operating Profit After Tax** |  |
| &nbsp;&nbsp;&nbsp; GAAP net income | $557.1 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Adjustments to GAAP net income | 396.0 |
| &nbsp;&nbsp;&nbsp; Non-GAAP net income | $953.1 |
| &nbsp;&nbsp;&nbsp; Non-GAAP provision for income taxes | 229.0 |
| &nbsp;&nbsp;&nbsp; GAAP interest expense | 120.4 |
| &nbsp;&nbsp;&nbsp; Non-GAAP other income | (95.5) |
| &nbsp;&nbsp;&nbsp; Adjusted net operating profit before tax | $1207.0 |
| &nbsp;&nbsp;&nbsp; Non-GAAP average effective tax rate (1) | 19.37% |
| &nbsp;&nbsp;&nbsp; Adjusted net operating profit after tax | $973.2 |
|  **Average Net Debt plus Average Stockholders' Equity (2)** |  |
| &nbsp;&nbsp;&nbsp; Average total debt | $2526.0 |
| &nbsp;&nbsp;&nbsp; Less: Average cash and cash equivalents | (2087.1) |
| &nbsp;&nbsp;&nbsp; Average net debt | $438.9 |
| &nbsp;&nbsp;&nbsp; Average stockholders' equity (3) | 6575.3 |
| &nbsp;&nbsp;&nbsp; Average net debt plus average stockholders' equity | $7014.2 |
|  **Adjusted Return on Invested Capital** | **13.9%** |

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(1) ROIC is presented on a TTM basis; non-GAAP effective tax rate for the three months ended September 28, 2024 was 19.75%, the three months ended December 28, 2024 was 19.50%, the three months ended March 29, 2025 was 19.00% and the three months ended June 28, 2025 was 19.25%.

(2) Calculated using the average of the balances as of June 28, 2025 and June 29, 2024.

(3) For Adjusted ROIC, stockholder's equity is adjusted (increased) to eliminate the effect of the impairment of intangible assets of $32.2 million in fiscal 2014, the impairment of goodwill of $685.7 million and an IPR&D asset of $46.0 million in fiscal 2018, the impairment of intangible assets and equipment of $685.4 million in fiscal 2019, the impairment of intangible assets and equipment of $30.2 million in fiscal 2020, the impairment of intangible assets of $45.1 million in fiscal 2022, the impairment of intangible assets and equipment of $223.8 million in fiscal 2023, the impairment of an intangible asset of $4.3 million in the first quarter of fiscal 2024, $26.8 million in the second quarter of fiscal 2024, and $13.7 million in the third quarter of fiscal 2024 and the impairment of intangible assets of $220.9 million in the second quarter of fiscal 2025. The impact of the intangible asset impairment charges is reflected net of tax.

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| | |
|:---|:---|
|  | **As of June 28, 2025**<br>**Net Leverage Ratio:** |
|  Total principal debt | $2519.4 |
|  Total cash and cash equivalents | $(1735.2) |
|  Net principal debt | $784.2 |
|  EBITDA for the last four quarters | $1316.3 |
|  Net Leverage Ratio | 0.6 |

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#### Other Supplemental Information:

#### <br>

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| | | | | |
|:---|:---|:---|:---|:---|
|  | **Three Months Ended** | **Three Months Ended** | **Nine Months Ended** | **Nine Months Ended** |
|  | **June 28, 2025** | **June 29, 2024** | **June 28, 2025** | **June 29, 2024** |
|  **Geographic Revenues** | | | | |
|  United States | 74.3% | 75.7% | 74.2% | 74.9% |
|  Europe | 14.5% | 12.6% | 14.5% | 13.4% |
|  Asia-Pacific | 5.9% | 6.4% | 5.9% | 6.4% |
|  Rest of World | 5.3% | 5.3% | 5.4% | 5.3% |
|  Total Revenues | 100.0% | 100.0% | 100.0% | 100.0% |

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