# EDGAR Filing Document

**Accession Number:** 0001888886
**File Stem:** 0000318989-23-000054
**Filing Date:** 2023-2
**Character Count:** 11090
**Document Hash:** fdb7703b2badd43f97fc9c1ecf94003b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000318989-23-000054.hdr.sgml**: 20230209

**ACCESSION NUMBER**: 0000318989-23-000054

**CONFORMED SUBMISSION TYPE**: 4

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20230207

**FILED AS OF DATE**: 20230209

**DATE AS OF CHANGE**: 20230209

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** FIL Ltd
- **CENTRAL INDEX KEY:** 0000318989
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-41608
- **FILM NUMBER:** 23605463

**BUSINESS ADDRESS:**
- **STREET 1:** P.O. BOX H.M. 670
- **CITY:** HAMILTON
- **STATE:** D0
- **ZIP:** 00000
- **BUSINESS PHONE:** 617-563-7000

**MAIL ADDRESS:**
- **STREET 1:** P.O. BOX H.M. 670
- **CITY:** HAMILTON
- **STATE:** D0
- **ZIP:** 00000

**FORMER NAME:**
- **FORMER CONFORMED NAME:** FIL LTD
- **DATE OF NAME CHANGE:** 20080213

**FORMER NAME:**
- **FORMER CONFORMED NAME:** FIDELITY INTERNATIONAL LTD
- **DATE OF NAME CHANGE:** 19920929
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Structure Therapeutics Inc.
- **CENTRAL INDEX KEY:** 0001888886
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 981480821
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 611 GATEWAY BLVD SUITE 223
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080
- **BUSINESS PHONE:** (628) 229-9277

**MAIL ADDRESS:**
- **STREET 1:** 611 GATEWAY BLVD SUITE 223
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** ShouTi Inc.
- **DATE OF NAME CHANGE:** 20211019

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 4

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[x] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[ ] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>FIL Ltd<br><sub>(Last) (First) (Middle)</sub><br>P.O. BOX H.M. 670<br><sub>(Street)</sub><br>HAMILTON, D0 00000<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2023-02-07 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director [ ] 10% Owner<br>[ ] Officer (give title below) [X] Other (specify below)<br>_See Remark 1_ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>Structure Therapeutics Inc. [ GPCR ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[X] Form filed by One Reporting Person<br>[ ] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Ordinary Shares | 2023-02-07 |  | C |  | 4013678 | A | <sup>(1)</sup> | 4013678 | I | Eight Roads Investments |
| Ordinary Shares | 2023-02-07 |  | C |  | 620499 | A | <sup>(1)</sup> | 4634177 | I | Eight Roads Investments |
| Ordinary Shares | 2023-02-07 |  | C |  | 452867 | A | <sup>(1)</sup> | 5087044 | I | Eight Roads Investments |
| Ordinary Shares | 2023-02-07 |  | C |  | 179242 | A | <sup>(1)</sup> | 5266286 | I | Eight Roads Investments |
| Ordinary Shares | 2023-02-07 |  | C |  | 71636 | A | <sup>(1)</sup> | 71636 | I | ERVC Healthcare Advisors IV, LP |
| Ordinary Shares | 2023-02-07 |  | C |  | 10154 | A | <sup>(1)</sup> | 81790 | I | ERVC Healthcare Advisors IV, LP |
| Ordinary Shares | 2023-02-07 |  | C |  | 7411 | A | <sup>(1)</sup> | 89201 | I | ERVC Healthcare Advisors IV, LP |
| Ordinary Shares | 2023-02-07 |  | C |  | 494035 | A | <sup>(1)</sup> | 494035 | I | ERVC Healthcare V, LP |
| Ordinary Shares | 2023-02-07 |  | C |  | 624239 | A | <sup>(1)</sup> | 624239 | I | ERVC Healthcare IV, LP |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| Series A Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 4013678 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 4013678 | <sup>(1)</sup> | 0 | I | Eight Roads Investments |
| Series A+ Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 620499 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 620499 | <sup>(1)</sup> | 0 | I | Eight Roads Investments |
| Series B Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 452867 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 452867 | <sup>(1)</sup> | 0 | I | Eight Roads Investments |
| Series B-1 Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 179242 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 179242 | <sup>(1)</sup> | 0 | I | Eight Roads Investments |
| Series A Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 71636 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 71636 | <sup>(1)</sup> | 0 | I | ERVC Healthcare Advisors IV, LP |
| Series A+ Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 10154 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 10154 | <sup>(1)</sup> | 0 | I | ERVC Healthcare Advisors IV, LP |
| Series B Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 7411 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 7411 | <sup>(1)</sup> | 0 | I | ERVC Healthcare Advisors IV, LP |
| Series B-1 Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 494035 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 494035 | <sup>(1)</sup> | 0 | I | ERVC Healthcare V, LP |
| Series A Convertible Preferred Shares | <sup>(1)</sup> | 2023-02-07 |  | C |  |  | 624239 | <sup>(1)</sup> | <sup>(1)</sup> | Ordinary Shares | 624239 | <sup>(1)</sup> | 0 | I | ERVC Healthcare IV, LP |

---

### Footnotes:

(1) On February 7, 2023, in connection with the completion of the issuer's initial public offering, each share of  Series A, A+, B, and B-1 Preferred Shares converted on a 1-for-1 basis into Ordinary Shares.

**Remarks:**
Remark 1:Eight Roads Shareholdings Limited ("ERSL") and Pandanus Partners, LP ("Pandanus") own shares of Eight Roads Holdings Limited ("ERHL") voting stock. ERHL is the immediate parent company of Eight Roads Investments ("ERI"), which owns the shares being reported on with this Form. While the percentage of total voting power represented by ERSL's and Pandanus' shares of ERHL voting stock may fluctuate due to changes in the total number of shares of ERHL voting stock outstanding from time to time, ERSL's holdings represents more than 50% and Pandanus' holding represents more than 25% and less than 50% of, the total votes which may be cast by all holders of ERHL voting stock. The shares in ERSL are owned primarily by officers and senior employees of FIL Limited and Eight Roads together with several charitable organizations.  No such person or organization owns or controls more than 25% of the voting stock in ERSL. Pandanus Associates, Inc. ("PAI")acts as general partner of Pandanus. Pandanus is owned by trusts for the benefit of members of the Johnson family, including ERHL's Chairman Abigail P. Johnson, but disclaims that any such member is a beneficial owner of the securities reported on this form. The address of ERSL, ERHL and ERI is 42 Crow Lane, Hamilton HM19, Bermuda. The address of Pandanus is c/o FIL Limited, 42 Crow Lane, Hamilton HM19, Bermuda. The address of PAI is 11 Keewaydin Drive, Suite 100, Salem, NH, USA, 03079. ERVC Healthcare IV, LP and ERVC Healthcare V, LP (Collectively "ERVC HC") are limited partners. The General Partners of ERVC HC are ERVC Healthcare Advisors V, LP and ERVC Healthcare Advisors IV, LP (collectively "ERVC HCA").The general partner of ERVC HCA is Eight Roads GP, which is controlled by ERSL.
Remark 2:The filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, the undersigned are the beneficial owners of any securities reported herein.

**Signature:** Stephanie J. Brown, Duly authorized under Powers of Attorney, by and on behalf of FIL Limited, Eight Roads Shareholdings Limited, and its direct and indirect subsidiaries, Eight Roads Holdings Limited and Eight Roads Investments  
**Date:** 2023-02-09

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**