# EDGAR Filing Document

**Accession Number:** 0001815620
**File Stem:** 0001193125-25-273377
**Filing Date:** 2025-11
**Character Count:** 3396
**Document Hash:** aff61a570ff37f3df53085cc2d83415a
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-25-273377.hdr.sgml**: 20251110

**ACCESSION NUMBER**: 0001193125-25-273377

**CONFORMED SUBMISSION TYPE**: 25

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20251110

**DATE AS OF CHANGE**: 20251110

**EFFECTIVENESS DATE**: 20251110

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Opthea Ltd
- **CENTRAL INDEX KEY:** 0001815620
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 000000000
- **STATE OF INCORPORATION:** C3
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** 25
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-39621
- **FILM NUMBER:** 251464601

**BUSINESS ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** LEVEL 4
- **STREET 2:** 650 CHAPEL STREET
- **CITY:** SOUTH YARRA
- **NON US STATE TERRITORY:** VICTORIA
- **PROVINCE COUNTRY:** C3
- **ZIP:** 3141
- **BUSINESS PHONE:** 61 3 9826 0399

**MAIL ADDRESS:**
- **ADDRESS IS A NON US LOCATION:** YES
- **STREET 1:** LEVEL 4
- **STREET 2:** 650 CHAPEL STREET
- **CITY:** SOUTH YARRA
- **NON US STATE TERRITORY:** VICTORIA
- **PROVINCE COUNTRY:** C3
- **ZIP:** 3141

**UNITED STATES** 

**SECURITIES AND EXCHANGE COMMISSION** 

**Washington, D.C. 20549** 

**FORM 25** 

**NOTIFICATION OF REMOVAL FROM LISTING** 

**AND/OR REGISTRATION UNDER SECTION 12(b)**

**OF THE SECURITIES EXCHANGE ACT OF 1934** 

**Commission File Number 001-39621** 

## Opthea Limited
**The Nasdaq Global Select Market**

**(Exact name of Issuer as specified in its charter, and name of Exchange where security is listed and/or registered)** 

**C/- Prime Company Compliance, Level 9** 

**505 Little Collins Street** 

**Melbourne, VIC 3000** 

**Australia** 

**+ 61 3 9826 0399** 

**(Address, including zip code, and telephone number, including area code, of Issuer's principal executive offices)** 

**American Depositary Shares, each representing eight ordinary shares, no par value**

**(Description of class of securities)** 

Please place an X in the box to designate the rule provision relied upon to strike the class of securities from listing and registration:

☐ 17 CFR 240.12d2-2(a)(1)

☐ 17 CFR 240.12d2-2(a)(2)

☐ 17 CFR 240.12d2-2(a)(3)

☐ 17 CFR 240.12d2-2(a)(4)

☐ Pursuant to 17 CFR 240.12d2-2(b), the Exchange has complied with its rules to strike the class of securities from listing and/or withdraw registration on the Exchange.

☒ Pursuant to 17 CFR 240.12d2-2(c), the Issuer has complied with the
rules of the Exchange and the requirements of 17 CFR 240.12d2-2(c) governing the voluntary withdrawal of the class of securities from listing and registration on the Exchange.

As of the date hereof, the Issuer does not have an audit committee that meets the audit committee composition requirements set forth in Nasdaq Listing Rule 5605(c)(2).

Pursuant to the requirements of the Securities Exchange Act of 1934, Opthea Limited certifies that it has reasonable grounds to believe that it meets all of the requirements for filing the Form 25 and has caused this notification to be signed on its behalf by the undersigned duly authorized person.

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| | | |
|:---|:---|:---|
|  | **Opthea Limited** | **Opthea Limited** |
| Date: November 10, 2025 | By: | /s/ Jeremy Levin |
|  | Name: | Jeremy Levin |
|  | Title: | Chief Executive Officer |

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