# EDGAR Filing Document

**Accession Number:** 0001907685
**File Stem:** 0001193125-23-028450
**Filing Date:** 2023-2
**Character Count:** 1938
**Document Hash:** 9ea384ac0cb8f1a05de1fe40561aa69b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-23-028450.hdr.sgml**: 20230313

**ACCESSION NUMBER**: 0001193125-23-028450

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20230208

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Comera Life Sciences Holdings, Inc.
- **CENTRAL INDEX KEY:** 0001907685
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 874706968
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 12 GILL STREET
- **STREET 2:** SUITE 4650
- **CITY:** WOBURN
- **STATE:** MA
- **ZIP:** 01801
- **BUSINESS PHONE:** (617)871-2101

**MAIL ADDRESS:**
- **STREET 1:** 12 GILL STREET
- **STREET 2:** SUITE 4650
- **CITY:** WOBURN
- **STATE:** MA
- **ZIP:** 01801

**Comera Life Sciences Holdings, Inc.** 

**12 Gill Street, Suite 4650** 

**Woburn, Massachusetts 01801** 

February 8, 2023

**<u>VIA EDGAR</u>**

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Re: Comera Life Sciences Holdings, Inc.

Registration Statement on Form S-1

File No. 333-269564

<u>Request for Acceleration</u>

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Comera Life Sciences Holdings, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-1, as amended (File No. 333-269564) so that it may become effective at 4:00 p.m. Eastern time on February 10, 2023, or as soon thereafter as practicable.

*[Remainder of this page intentionally left blank]* 

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| | |
|:---|:---|
|  Very truly yours, | Very truly yours, |
|  Comera Life Sciences Holdings, Inc. | Comera Life Sciences Holdings, Inc. |
| By: | /s/ Jeffrey S. Hackman |
|  Name: | Jeffrey S. Hackman |
|  Title: | Chairman, President and CEO |

---