# EDGAR Filing Document

**Accession Number:** 0001818382
**File Stem:** 0001104659-25-091324
**Filing Date:** 2025-9
**Character Count:** 2210
**Document Hash:** 6fac3457e4aaa66dda44e10167dc4ead
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001104659-25-091324.hdr.sgml**: 20260113

**ACCESSION NUMBER**: 0001104659-25-091324

**CONFORMED SUBMISSION TYPE**: CORRESP

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20250918

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Humacyte, Inc.
- **CENTRAL INDEX KEY:** 0001818382
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 851763759
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** CORRESP

**BUSINESS ADDRESS:**
- **STREET 1:** 2525 EAST NORTH CAROLINA HIGHWAY 54
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27713
- **BUSINESS PHONE:** 919-313-9633

**MAIL ADDRESS:**
- **STREET 1:** 2525 EAST NORTH CAROLINA HIGHWAY 54
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27713

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Alpha Healthcare Acquisition Corp.
- **DATE OF NAME CHANGE:** 20200716

![](tm2525852d4_correspimg01.jpg)

September 18, 2025

**Via EDGAR**

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attn: Alan Campbell

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| | |
|:---|:---|
| **Re:** | **Humacyte, Inc.** |
|  | **Registration Statement Filed on Form S-3 (the "Registration Statement")** |
|  | **File No. 333-290231** |

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Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Humacyte, Inc. (the "Company") hereby respectfully requests that the effective date for the above-referenced Registration Statement be accelerated to 4:00 p.m., Eastern Time, on September 22, 2025, or as soon as practicable thereafter.

Please contact Kerry S. Burke of Covington & Burling LLP at (202) 662-5297 or kburke@cov.com with any questions you may have regarding this request. In addition, please notify Ms. Burke by telephone when this request for acceleration has been granted.

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| | |
|:---|:---|
| Respectfully, | Respectfully, |
| **Humacyte, Inc.** | **Humacyte, Inc.** |
| By: | /s/ Dale A. Sander |
| Name: | Dale A. Sander |
| Title: | Chief Financial Officer |

---

cc: Kerry S. Burke, Covington & Burling LLP