# EDGAR Filing Document

**Accession Number:** 0001348911
**File Stem:** 0000950170-23-000615
**Filing Date:** 2023-1
**Character Count:** 27106
**Document Hash:** cd8ce5bc1f2b09375668560c1b03eb8f
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000950170-23-000615.hdr.sgml**: 20230110

**ACCESSION NUMBER**: 0000950170-23-000615

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 4

**FILED AS OF DATE**: 20230110

**DATE AS OF CHANGE**: 20230110

**EFFECTIVENESS DATE**: 20230110

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** KalVista Pharmaceuticals, Inc.
- **CENTRAL INDEX KEY:** 0001348911
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 200915291
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0430

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-269174
- **FILM NUMBER:** 23521288

**BUSINESS ADDRESS:**
- **STREET 1:** 55 CAMBRIDGE PARKWAY
- **STREET 2:** SUITE 901E
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02142
- **BUSINESS PHONE:** (857) 999-0075

**MAIL ADDRESS:**
- **STREET 1:** 55 CAMBRIDGE PARKWAY
- **STREET 2:** SUITE 901E
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02142

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Carbylan Therapeutics, Inc.
- **DATE OF NAME CHANGE:** 20140916

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Carbylan Biosurgery, Inc
- **DATE OF NAME CHANGE:** 20130102

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Carbylan Biosurgery Inc
- **DATE OF NAME CHANGE:** 20060105

**As filed with the Securities and Exchange Commission on January 10, 2023**

**Registration No. 333-** 

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**<u>______________________</u>**

**FORM S-8**

**REGISTRATION STATEMENT UNDER THE Securities Act of 1933**

**<u>______________________</u>**

**KALVISTA PHARMACEUTICALS, INC.**

(Exact Name of Registrant as Specified in Its Charter)

---

| | |
|:---|:---|
| &nbsp;&nbsp;**Delaware** | &nbsp;&nbsp;**20-0915291** |
| &nbsp;&nbsp;(State or Other Jurisdiction<br>of Incorporation or Organization) | &nbsp;&nbsp;(I.R.S. Employer<br>Identification No.) |

---

**KalVista Pharmaceuticals, Inc.<br>55 Cambridge Parkway**

**Suite 901E<br>Cambridge, MA 02142**

(Address of Principal Executive Offices) (Zip Code)****

<br> **2017 Equity Incentive Plan**

**2017 Employee Stock Purchase Plan** 

(Full Title of the Plans)

**Thomas Andrew Crockett**

**Chief Executive Officer**

**KalVista Pharmaceuticals, Inc.<br>55 Cambridge Parkway**

**Suite 901E<br>Cambridge, MA 02142**

(Name and Address of Agent For Service)

**(857) 999-0075**

(Telephone Number, including area code, of agent for service)

**Copies to:**

**Robert A. Freedman, Esq.**

**Julia Forbess, Esq.**

**Fenwick & West LLP**

**555 California Street, 12**<sup>th</sup> **Floor**

**San Francisco, California 94104**

**(415) 875-2300** 

**Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.** 

---

| | |
|:---|:---|
| &nbsp;&nbsp;Large accelerated filer  | &nbsp;&nbsp;Accelerated filer  |
| &nbsp;&nbsp;Non-accelerated filer <br>| &nbsp;&nbsp;Smaller reporting company  |
|  | &nbsp;&nbsp;Emerging growth company  |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. 

------

**STATEMENT PURSUANT TO GENERAL INSTRUCTION E TO FORM S-8**

**REGISTRATION OF ADDITIONAL SECURITIES**

KalVista Pharmaceuticals, Inc. (the "**Registrant**") is filing this Registration Statement with the Securities and Exchange Commission (the "**Commission**") to register (a) 1,364,094 additional shares of common stock available for issuance under the Registrant's 2017 EIP, pursuant to the provision of the 2017 EIP providing for an annual 4% automatic increase in the number of shares reserved for issuance and (b) 341,023 additional shares of common stock available for issuance under the Registrant's 2017 ESPP, pursuant to the provision of the 2017 ESPP providing for an annual 1% automatic increase in the number of shares reserved for issuance.

In accordance with General Instruction E of Form S-8, and only with respect to the common stock issuable under the 2017 EIP and 2017 ESPP, this Registration Statement hereby incorporates by reference the contents of the Registrant's Registration Statements on Form S-8 filed with the Commission on March 29, 2017 (Registration No. 333-217008), on July 30, 2018 (Registration No. 333-226442), on March 14, 2019 (Registration No. 333-230279), on March 10, 2020 (Registration No. 333-237059), on March 11, 2021 (Registration No. 333-257871), and on March 10, 2022 (Registration No. 333-263431) to the extent not superseded hereby.

------

**PART II**

**Information Required in the Registration Statement**

**Item 3. <u>Incorporation of Documents by Reference</u>.** 

The following documents filed by the Registrant with the Commission pursuant to the Securities Act and the Securities Exchange Act of 1934, as amended (the "**Exchange Act**"), are incorporated herein by reference, except that the Registrant is not incorporating by reference any information furnished (and not filed) with the Commission, including any information furnished pursuant to Items 2.02 or 7.01 of Form 8-K or related exhibits furnished pursuant to Item 9.01 of Form 8-K:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a)The Registrant's Annual Report on [<u>Form 10-K</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017022012521/kalv-20220430.htm) for the fiscal year ended April 30, 2022, filed with the Commission on July 7, 2022;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b)The Registrant's Quarterly Reports on Form 10-Q for the three months ended July 31, 2022 and October 31, 2022 filed with the Commission on [<u>September 8, 2022</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017022018239/kalv-20220731.htm) and [<u>December 8, 2022</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017022026230/kalv-20221031.htm) respectively;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c)The Registrant's Current Reports on Form 8-K filed with the Commission on [<u>March 7, 2022</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017022002956/kalv-20220307.htm), [<u>May 27, 2022</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017022010855/kalv-20220525.htm), [<u>October 17, 2022</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017022019610/kalv-20221013.htm)<u>,</u> [<u>December 27, 2022</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000119312522312030/d420223d8k.htm)and [<u>January 5, 2023</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1348911/000095017023000230/kalv-20230104.htm);

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d)All other reports filed pursuant to Section 13(a) or 15(d) of the Exchange Act since the end of the fiscal year covered by the Registrant's Annual Report referred to in (a) above; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e)The description of the Registrant's common stock contained in the Registrant's Registration Statement on [<u>Form 8-A</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312515029700/d864214d8a12b.htm) (registration number 001-36830) filed with the Commission on February 2, 2015 under Section 12(b) of the Exchange Act, including any amendments or reports filed for the purpose of updating such description.

All documents filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, subsequent to the filing of this Registration Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement and to be part hereof from the date of filing of such documents, except as to specific sections of such documents as set forth therein. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document, which also is deemed to be incorporated by reference herein, modifies or supersedes such statement.

**Item 8. <u>Exhibits</u>.** 

The following exhibits are filed herewith:

------

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| &nbsp;&nbsp;**Exhibit** |  | &nbsp;&nbsp; **<u>Incorporated by Reference</u>** | &nbsp;&nbsp; **<u>Incorporated by Reference</u>** | &nbsp;&nbsp; **<u>Incorporated by Reference</u>** | &nbsp;&nbsp; **<u>Incorporated by Reference</u>** | &nbsp;&nbsp;**Filed** |
| &nbsp;&nbsp;**<u>Number</u>** | &nbsp;&nbsp;**<u>Exhibit Description</u>** | &nbsp;&nbsp;**<u>Form</u>** | &nbsp;&nbsp;**<u>File No.</u>** | &nbsp;&nbsp;**<u>Exhibit</u>** | &nbsp;&nbsp;**<u>Filing Date</u>** | &nbsp;&nbsp;**<u>Herewith</u>** |
| &nbsp;&nbsp;4.1 | &nbsp;&nbsp;[<u>Amended and Restated Certificate of Incorporation</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312515133269/d908546dex31.htm) | &nbsp;&nbsp;8-K | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;3.1 | &nbsp;&nbsp;April 16, 2015 |  |
| &nbsp;&nbsp;4.2 | &nbsp;&nbsp;[<u>Certificate of Amendment to the Restated Certificate of Incorporation</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312516776615/d296713dex31.htm) | &nbsp;&nbsp;8-K | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;3.1 | &nbsp;&nbsp;November 23, 2016 |  |
| &nbsp;&nbsp;4.3 | &nbsp;&nbsp;[<u>Certificate of Amendment (Name Change) to the Restated Certificate of Incorporation</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312516776615/d296713dex32.htm) | &nbsp;&nbsp;8-K | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;3.2 | &nbsp;&nbsp;November 23, 2016 |  |
| &nbsp;&nbsp;4.4 | &nbsp;&nbsp;[<u>Amended and Restated Bylaws, as amended</u>](https://www.sec.gov/Archives/edgar/data/1348911/000156459021035225/kalv-ex31_8.htm) | &nbsp;&nbsp;8-K | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;3.4 | &nbsp;&nbsp;June 30, 2021  |  |
| &nbsp;&nbsp;4.5 | &nbsp;&nbsp;[<u>Form of Common Stock Certificate</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312515018035/d781411dex42.htm) | &nbsp;&nbsp;S-1/A | &nbsp;&nbsp;333-201278 | &nbsp;&nbsp;4.2 | &nbsp;&nbsp;January 23, 2015 |  |
| &nbsp;&nbsp;5.1 | &nbsp;&nbsp;[<u>Opinion and Consent of Fenwick & West LLP</u><u>.</u>](kalv-ex5_1.htm) |  |  |  |  | &nbsp;&nbsp;**X** |
| &nbsp;&nbsp;23.1 | &nbsp;&nbsp;[<u>Consent of Deloitte & Touche LLP, independent registered public accounting firm.</u>](kalv-ex23_1.htm) |  |  |  |  | &nbsp;&nbsp;**X** |
| &nbsp;&nbsp;23.2 | &nbsp;&nbsp;[<u>Consent of Fenwick & West LLP (contained in Exhibit 5.1).</u>](kalv-ex5_1.htm) |  |  |  |  | &nbsp;&nbsp;**X** |
| &nbsp;&nbsp;24.1 | &nbsp;&nbsp;[<u>Power of Attorney (included on the signature page to this Registration Statement).</u>](#node7) |  |  |  |  | &nbsp;&nbsp;**X** |
| &nbsp;&nbsp;99.1 | &nbsp;&nbsp;[<u>2017 Equity Incentive Plan.</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312517067690/d352394ddef14a.htm) | &nbsp;&nbsp;DEF 14A | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;Appendix A | &nbsp;&nbsp;March 2, 2017 |  |
| &nbsp;&nbsp;99.2 | &nbsp;&nbsp;[<u>2017 Employee Stock Purchase Plan.</u>](https://www.sec.gov/Archives/edgar/data/1348911/000119312517067690/d352394ddef14a.htm) | &nbsp;&nbsp;DEF 14A | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;Appendix B | &nbsp;&nbsp;March 2, 2017 |  |
| &nbsp;&nbsp;99.3 | &nbsp;&nbsp;[<u>Forms of Equity Award Agreements under the 2017 Equity Incentive Plan.</u>](https://www.sec.gov/Archives/edgar/data/1348911/000156459018016455/kalv-ex991_20.htm) | &nbsp;&nbsp;8-K | &nbsp;&nbsp;001-36830 | &nbsp;&nbsp;99.1 | &nbsp;&nbsp;June 29, 2018 |  |
| &nbsp;&nbsp;99.4 | &nbsp;&nbsp;[<u>Enrollment/Change Form under the 2017 Employee Stock Purchase Plan.</u>](https://www.sec.gov/Archives/edgar/data/1348911/000156459020009778/kalv-ex994_35.htm) | &nbsp;&nbsp;S-8 | &nbsp;&nbsp;333-237059 | &nbsp;&nbsp;99.4 | &nbsp;&nbsp;March 10, 2020 |  |
| &nbsp;&nbsp;107 | &nbsp;&nbsp;[<u>Filing Fee Table</u>](kalv-exfiling_fees.htm) |  |  |  |  | &nbsp;&nbsp;**X** |

---

------

**SIGNATURES**

Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cambridge, the Commonwealth of Massachusetts, on January 10, 2023.

**KALVISTA PHARMACEUTICALS, INC.**

By: <u>/s/ T. Andrew Crockett</u>

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;T. Andrew Crockett<br>Chief Executive Officer

**POWER OF ATTORNEY**

 **KNOW ALL PERSONS BY THESE PRESENTS**, that each person whose signature appears below does hereby constitute and appoint Thomas Andrew Crockett and Benjamin L. Palleiko, and each of them, with full power of substitution, such person's true and lawful attorneys-in-fact and agents for such person, with full power and authority to do any and all acts and things and to execute any and all instruments which said attorneys and agents, and any one of them, determine may be necessary or advisable or required to enable said corporation to comply with the Securities Act of 1933, as amended, and any rules or regulations or requirements of the Securities and Exchange Commission in connection with this Registration Statement. Without limiting the generality of the foregoing power and authority, the powers granted include the power and authority to sign the names of the undersigned officers and directors in the capacities indicated below to this Registration Statement, to any and all amendments, both pre-effective and post-effective, and supplements to this Registration Statement, and to any and all instruments or documents filed as part of or in conjunction with this Registration Statement or amendments or supplements thereof, and each of the undersigned hereby ratifies and confirms that all said attorneys and agents, or any one of them, shall do or cause to be done by virtue hereof. This Power of Attorney may be signed in several counterparts.

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons on behalf of the Registrant in the capacities and on the dates indicated.

------

---

| | | |
|:---|:---|:---|
| &nbsp;&nbsp;**<u>Signature</u>** | &nbsp;&nbsp;**<u>Title</u>** | &nbsp;&nbsp;**<u>Date</u>** |
| &nbsp;&nbsp;<u>/s/ T. Andrew Crockett</u> <br>T. Andrew Crockett | &nbsp;&nbsp;Chief Executive Officer and Director<br>(Principal Executive Officer) | &nbsp;&nbsp;January 10, 2023 |
| &nbsp;&nbsp;<u>/s/ Benjamin L. Palleiko</u> <br>Benjamin L. Palleiko | &nbsp;&nbsp;President, Chief Business Officer and Chief Financial Officer<br>(Principal Financial and Accounting Officer) | &nbsp;&nbsp;January 10, 2023 |
| &nbsp;&nbsp;<u>/s/ Albert Cha, M.D., Ph.D.</u> <br>Albert Cha, M.D., Ph.D. | &nbsp;&nbsp;Director  | &nbsp;&nbsp;January 10, 2023 |
| &nbsp;&nbsp;<u>/s/ Brian J. G. Pereira, M.D.</u> <br>Brian J. G. Pereira, M.D. | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 10, 2023 |
| &nbsp;&nbsp;<u>/s/ Nancy Stuart</u> <br>Nancy Stuart | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 10, 2023 |
| &nbsp;&nbsp;<u>/s/ Patrick Treanor</u> <br>Patrick Treanor | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 10, 2023 |
| &nbsp;&nbsp;<u>/s/ Edward W. Unkart</u> <br>Edward W. Unkart | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 10, 2023 |

---

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## Exhibit 5.1

**<u>EXHIBIT 5.1</u>**

January 10, 2023

KalVista Pharmaceuticals, Inc.<br>55 Cambridge Parkway<br>Suite 901E<br>Cambridge, MA 02142

Ladies and Gentlemen:

At your request, as your counsel, we have examined the Registration Statement on Form S-8 (the "**Registration Statement**") to be filed by KalVista Pharmaceuticals, Inc., a Delaware corporation (the "**Company**") with the Securities and Exchange Commission (the "**Commission**") on or about January 10, 2023 in connection with the registration under the Securities Act of 1933, as amended (the "**Securities Act**"), of an aggregate of 1,705,117 shares (the "**Shares**") of the Company's Common Stock, $0.001 par value per share (the "**Common Stock**"), subject to issuance by the Company (a) upon the exercise or settlement of equity awards granted or to be granted under the Company's 2017 Equity Incentive Plan, as amended to date (the "**2017 EIP**") pursuant to the provision of the 2017 EIP providing for an annual 4% automatic increase in the number of shares reserved for issuance under the 2017 EIP and (b) pursuant to purchase rights granted or to be granted under the Company's 2017 Employee Stock Purchase Plan, as amended to date (the "**2017 ESPP**") pursuant to the provision of the 2017 ESPP providing for an annual 1% automatic increase in the number of shares reserved for issuance under the 2017 ESPP. The 2017 EIP and the 2017 ESPP are each individually referred to herein as a "**Plan**" and collectively as the "**Plans**".

At your request we are providing this letter to express our opinion on the matters set forth below in this letter ("**our opinion**").

In connection with our opinion, we have examined such matters of fact as we have deemed necessary, which included examination of originals or copies of: the Company's current Amended and Restated Certificate of Incorporation, as amended, and Amended and Restated Bylaws, as amended (collectively, the "**Charter Documents**"), the Plans, the Registration Statement and the exhibits thereto; the prospectuses relating to the Plans; certain corporate proceedings of the Company's Board of Directors (the "**Board**")**,** the Compensation Committee of the Board and the Company's stockholders relating to adoption or approval of the Company Charter Documents, the Plans, the reservation of the Shares for sale and issuance, the filing of the Registration Statement and the registration of the Shares under the Securities Act and documents (including a certificate from the Company's transfer agent) regarding the Company's outstanding and reserved capital stock and other securities and such other documents as we have deemed advisable, and we have examined such questions of law as we have considered necessary.

In our examination of documents for purposes of this opinion, we have assumed, and express no opinion as to, the authenticity and completeness of all documents submitted to us as originals, the genuineness of signatures on documents reviewed by us, the conformity to originals and the completeness of all documents submitted to us as copies, the legal capacity of all parties executing any documents (other than the Company), the lack of any undisclosed termination or modification or waiver of any document, the absence of any extrinsic agreements or documents that might change or affect the interpretation or terms of documents, and the due authorization, execution and delivery of all documents by each party thereto other than the Company. We have also assumed that any certificates or instruments representing the Shares, when issued, will be executed by the Company by officers of the Company duly authorized to do so. In rendering our opinion, we have also relied upon a Certificate of Good Standing dated January 6, 2023 issued by the Delaware Secretary of State with respect to the Company and representations and certifications made

------

to us by the Company, including without limitation representations in a Management Certificate addressed to us of even date herewith that the Company has available a sufficient number of authorized shares of Common Stock that are not currently outstanding or reserved for issuance under other outstanding securities or plans of the Company, to enable the Company to issue and deliver all of the Shares as of the date of this letter.

We render this opinion only with respect to, and we express no opinion herein concerning the application or effect of the laws of any jurisdiction other than, the existing Delaware General Corporation Law now in effect. We express no opinion with respect to the securities or "blue sky" laws of any state.

Based upon, and subject to, the foregoing, it is our opinion that when the 1,705,117 Shares of Common Stock that may be issued and sold by the Company (a) upon the exercise or settlement of awards granted or to be granted under the 2017 EIP and (b) pursuant to purchase rights granted or to be granted under the 2017 ESPP, have been issued and sold by the Company against the Company's receipt of payment therefor (in an amount and type of consideration not less than the par value per Share) in accordance with the terms (including without limitation payment and authorization provisions) of the applicable Plan, and have been duly registered on the books of the transfer agent and registrar for the Shares in the name or on behalf of the holders thereof, such Shares will be validly issued, fully paid and non-assessable.

[Signature page follows]

------

We consent to the use of this opinion as an exhibit to the Registration Statement and further consent to all references to us, if any, in the Registration Statement, the prospectuses constituting a part thereof and any amendments thereto. We do not thereby admit that we are within the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of the Commission thereunder. This opinion is intended solely for use in connection with issuance and sale of the Shares subject to the Registration Statement and is not to be relied upon for any other purpose. In providing this letter, we are opining only as to the specific legal issues expressly set forth above, and no opinion shall be inferred as to any other matter or matters. This opinion is rendered on, and speaks only as of, the date of this letter first written above, and does not address any potential change in facts or law that may occur after the date of this opinion letter. We assume no obligation to advise you of any fact, circumstance, event or change in the law or the facts that may hereafter be brought to our attention, whether or not such occurrence would affect or modify any of the opinions expressed herein.

Very truly yours,

/s/ Fenwick & West LLP

**FENWICK & WEST LLP**

------

## Exhibit 23.1

**<u>EXHIBIT 23.1</u>**

**CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM**

We consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated July 7, 2022, relating to the financial statements of KalVista Pharmaceuticals, Inc. appearing in the Annual Report on Form 10-K of KalVista Pharmaceuticals, Inc. for the year ended April 30, 2022.

/s/ Deloitte & Touche LLP

Boston, Massachusetts

January 9, 2023

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## Ex-Filing

**<u>EXHIBIT 107</u>**

**CALCULATION OF FILING FEE TABLES**

**Form S-8**

(Form Type)

**KalVista Pharmaceuticals, Inc.**

(Exact Name of Registrant as Specified in Its Charter)

**Table 1 – Newly Registered Securities**

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| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| Security Type | Security Class Title | Fee Calculation Rule | Amount Registered(1) | Proposed Maximum Offering Price Per Unit | Maximum Aggregate Offering Price | Fee Rate | Amount of Registration Fee |
| Equity | Common stock, par value $0.001 per share, 2017 Equity Incentive Plan | Rule 457(c) and Rule 457(h) | 1364094(2) | $6.52 (4) | $8893892.88 | 0.0001102 | $980.11 |
| Equity | Common stock, par value $0.001 per share, 2017 Employee Stock Purchase Plane | Rule 457(c) and Rule 457(h) | 341023 (3) | $5.54 (5) | $1889267.42 | 0.0001102 | $208.20 |
| **Total Offering Amounts** | **Total Offering Amounts** | **Total Offering Amounts** | **Total Offering Amounts** |  |  |  | $1188.30 |
| **Total Fee Offsets** | **Total Fee Offsets** | **Total Fee Offsets** | **Total Fee Offsets** |  |  |  | &nbsp;&nbsp;&nbsp;&nbsp;— |
| **Net Fee Due** | **Net Fee Due** | **Net Fee Due** | **Net Fee Due** |  |  |  | $1188.30 |

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(1)Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "**Securities Act**"), this Registration Statement shall also cover any additional shares of the Registrant's common stock that become issuable in respect of the securities identified in the above table by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without receipt of consideration that increases the number of the Registrant's outstanding shares of common stock.

(2)Represents additional shares of common stock reserved for issuance under the Registrant's 2017 Equity Incentive Plan (the "**2017 EIP**") resulting from the annual 4% automatic increase in the number of authorized shares reserved for issuance under the 2017 EIP. The increase was effective as of January 1, 2022.

(3)Represents additional shares of common stock reserved for issuance under the Registrant's 2017 Employee Stock Purchase Plan (the "**2017 ESPP**") resulting from the annual 1% automatic increase in the number of authorized shares reserved for issuance under the 2017 ESPP. The increase was effective as of January 1, 2022.

(4)Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(c) and (h) under the Securities Act of 1933, as amended, based on the average of the high and low prices of the Registrant's common stock as reported by the Nasdaq Global Market on January 5, 2023.

(5)Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(c) and (h) under the Securities Act of 1933, as amended, based on the average of the high and low prices of the Registrant's common stock as reported by the Nasdaq Global Market on January 5, 2023, multiplied by 85%, which is the percentage of the trading price per share applicable to purchasers under the 2017 ESPP.

------