# EDGAR Filing Document

**Accession Number:** 0001640455
**File Stem:** 0001214659-23-003818
**Filing Date:** 2023-3
**Character Count:** 26321
**Document Hash:** ae50279d479bd7276c325d8552dc1ea0
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001214659-23-003818.hdr.sgml**: 20230314

**ACCESSION NUMBER**: 0001214659-23-003818

**CONFORMED SUBMISSION TYPE**: SC 13D

**PUBLIC DOCUMENT COUNT**: 2

**FILED AS OF DATE**: 20230314

**DATE AS OF CHANGE**: 20230314

**GROUP MEMBERS**: CONCENTRA BIOSCIENCES, LLC

**GROUP MEMBERS**: KEVIN TANG

**GROUP MEMBERS**: TANG CAPITAL MANAGEMENT, LLC

**SUBJECT COMPANY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Jounce Therapeutics, Inc.
- **CENTRAL INDEX KEY:** 0001640455
- **STANDARD INDUSTRIAL CLASSIFICATION:** BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
- **IRS NUMBER:** 454870634
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13D
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 005-89831
- **FILM NUMBER:** 23731823

**BUSINESS ADDRESS:**
- **STREET 1:** 780 MEMORIAL DRIVE
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02139
- **BUSINESS PHONE:** 857-259-3840

**MAIL ADDRESS:**
- **STREET 1:** 780 MEMORIAL DRIVE
- **CITY:** CAMBRIDGE
- **STATE:** MA
- **ZIP:** 02139
**FILED BY**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** TANG CAPITAL PARTNERS LP
- **CENTRAL INDEX KEY:** 0001191935
- **IRS NUMBER:** 680517277
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** SC 13D

**BUSINESS ADDRESS:**
- **STREET 1:** 4747 EXECUTIVE DRIVE
- **STREET 2:** SUITE 210
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121
- **BUSINESS PHONE:** 858-200-3830

**MAIL ADDRESS:**
- **STREET 1:** 4747 EXECUTIVE DRIVE
- **STREET 2:** SUITE 210
- **CITY:** SAN DIEGO
- **STATE:** CA
- **ZIP:** 92121

**SECURITIES AND EXCHANGE COMMISSION** **<br> Washington, DC 20549**

**SCHEDULE 13D**

**Under the securities exchange act of 1934<br> (amendment no. ___)\***

**Jounce Therapeutics, Inc.<br> (Name of Issuer)**

**Common Stock, par value $0.001 per share**<br> (Title of Class of Securities)

**481116101<br> (CUSIP Number)**

**Ryan A. Murr<br> James J. Moloney<br> Gibson, Dunn & Crutcher LLP<br> 555 Mission Street, Suite 3000<br> San Francisco, CA 94105<br> (Name, Address and Telephone Number of Person<br> Authorized to Receive Notices and Communications)**

**March 14, 2023<br> (Date of Event Which Requires Filing of This Statement)**

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ⌧

\*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("**Act**") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

---

| | | |
|:---|:---|:---|
| **CUSIP No. 481116101** | **CUSIP No. 481116101** | **CUSIP No. 481116101** |
| **1** | NAMES OF REPORTING PERSONS<br>TANG CAPITAL PARTNERS, LP | NAMES OF REPORTING PERSONS<br>TANG CAPITAL PARTNERS, LP |
| **2** | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP\* | (a) □<br>(b) □<br>|
| **3** | SEC USE ONLY | SEC USE ONLY |
| **4** | SOURCE OF FUNDS (SEE INSTRUCTIONS)<br>WC | SOURCE OF FUNDS (SEE INSTRUCTIONS)<br>WC |
| **5** | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ |
| **6** | CITIZENSHIP OR PLACE OF ORGANIZATION<br>DELAWARE | CITIZENSHIP OR PLACE OF ORGANIZATION<br>DELAWARE |

---

---

| | | |
|:---|:---|:---|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **7** | SOLE VOTING POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **8** | SHARED VOTING POWER<br>5,300,087<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **9** | SOLE DISPOSITIVE POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **10** | SHARED DISPOSITIVE POWER<br>5,300,087<br>|

---

---

| | |
|:---|:---|
| **11** | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>5,300,087<br>|
| **12** | CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES<br>□  |
| **13** | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 11<br>10.2%<br>|
| **14** | TYPE OF REPORTING PERSON<br>PN<br>|

---

Page 2 of 10 Pages

---

| | | |
|:---|:---|:---|
| **CUSIP No. 481116101** | **CUSIP No. 481116101** | **CUSIP No. 481116101** |
| **1** | NAMES OF REPORTING PERSONS<br>TANG CAPITAL MANAGEMENT, LLC | NAMES OF REPORTING PERSONS<br>TANG CAPITAL MANAGEMENT, LLC |
| **2** | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP\* | (a) □<br>(b) □<br>|
| **3** | SEC USE ONLY | SEC USE ONLY |
| **4** | SOURCE OF FUNDS (SEE INSTRUCTIONS)<br>WC | SOURCE OF FUNDS (SEE INSTRUCTIONS)<br>WC |
| **5** | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ |
| **6** | CITIZENSHIP OR PLACE OF ORGANIZATION<br>DELAWARE | CITIZENSHIP OR PLACE OF ORGANIZATION<br>DELAWARE |

---

---

| | | |
|:---|:---|:---|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **7** | SOLE VOTING POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **8** | SHARED VOTING POWER<br>5,300,087<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **9** | SOLE DISPOSITIVE POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **10** | SHARED DISPOSITIVE POWER<br>5,300,087<br>|

---

---

| | |
|:---|:---|
| **11** | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>5,300,087<br>|
| **12** | CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES<br>□  |
| **13** | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 11<br>10.2%<br>|
| **14** | TYPE OF REPORTING PERSON<br>OO<br>|

---

Page 3 of 10 Pages

---

| | | |
|:---|:---|:---|
| **CUSIP No. 481116101** | **CUSIP No. 481116101** | **CUSIP No. 481116101** |
| **1** | NAMES OF REPORTING PERSONS<br>KEVIN TANG | NAMES OF REPORTING PERSONS<br>KEVIN TANG |
| **2** | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP\* | (a) □<br>(b) □<br>|
| **3** | SEC USE ONLY | SEC USE ONLY |
| **4** | SOURCE OF FUNDS (SEE INSTRUCTIONS)<br>WC | SOURCE OF FUNDS (SEE INSTRUCTIONS)<br>WC |
| **5** | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ |
| **6** | CITIZENSHIP OR PLACE OF ORGANIZATION<br>UNITED STATES | CITIZENSHIP OR PLACE OF ORGANIZATION<br>UNITED STATES |

---

---

| | | |
|:---|:---|:---|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **7** | SOLE VOTING POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **8** | SHARED VOTING POWER<br>5,300,087<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **9** | SOLE DISPOSITIVE POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **10** | SHARED DISPOSITIVE POWER<br>5,300,087<br>|

---

---

| | |
|:---|:---|
| **11** | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>5,300,087<br>|
| **12** | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES<br>□  |
| **13** | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 11<br>10.2%<br>|
| **12** | TYPE OF REPORTING PERSON<br>IN<br>|

---

Page 4 of 10 Pages

---

| | | |
|:---|:---|:---|
| **CUSIP No. 481116101** | **CUSIP No. 481116101** | **CUSIP No. 481116101** |
| **1** | NAMES OF REPORTING PERSONS<br>Concentra Biosciences, LLC  | NAMES OF REPORTING PERSONS<br>Concentra Biosciences, LLC  |
| **2** | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP\* | (a) □<br>(b) □<br>|
| **3** | SEC USE ONLY | SEC USE ONLY |
| **4** | SOURCE OF FUNDS (SEE INSTRUCTIONS) | SOURCE OF FUNDS (SEE INSTRUCTIONS) |
| **5** | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ | CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) ◻ |
| **6** | CITIZENSHIP OR PLACE OF ORGANIZATION<br>UNITED STATES | CITIZENSHIP OR PLACE OF ORGANIZATION<br>UNITED STATES |

---

---

| | | |
|:---|:---|:---|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **7** | SOLE VOTING POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **8** | SHARED VOTING POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **9** | SOLE DISPOSITIVE POWER<br>0<br>|
| NUMBER OF<br> SHARES<br> BENEFICIALLY<br> OWNED BY<br> EACH REPORTING<br> PERSON WITH | **10** | SHARED DISPOSITIVE POWER<br>0<br>|

---

---

| | |
|:---|:---|
| **11** | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<br>0<br>|
| **12** | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES<br>□  |
| **13** | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 11<br>0%<br>|
| **12** | TYPE OF REPORTING PERSON<br>OO<br>|

---

Page 5 of 10 Pages

**Item 1.** **Security and Issuer**

This Statement on Schedule 13D (this "**Statement**") relates to shares of Common Stock, par value $0.001 per share (the "**Common Stock**" or "**Shares**") of Jounce Therapeutics, Inc., a Delaware corporation (the "**Issuer**"). The address of the principal executive offices of the Issuer is 780 Memorial Drive, Cambridge, MA 02139.

**Item 2.** **Identity and Background**

This Statement is filed by Tang Capital Partners, LP, a Delaware limited partnership engaged in capital management ("**Tang Capital Partners**"); Tang Capital Management, LLC, a Delaware limited liability company that is the general partner of Tang Capital Partners ("**Tang Capital Management**"); Concentra Biosciences, LLC, a Delaware limited liability company ("**Concentra**") and Kevin Tang, a United States citizen who is the manager of Tang Capital Management and Chief Executive Officer of Concentra ("**Kevin Tang**" and, collectively with Tang Capital Partners, Tang Capital Management and Concentra, the "**Reporting Persons**"). The address of each of the Reporting Persons is 4747 Executive Drive, Suite 210, San Diego, CA 92121.

During the past five years, none of the Reporting Persons has been: (i) convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors), or (ii) a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

### Item 3. Source and Amount of Funds or Other Consideration
The Common Stock was acquired with approximately $6.5 million of working capital set aside by Tang Capital Partners for the general purpose of investing. Tang Capital Partners, LP maintains commingled margin accounts with various financial institutions, which may extend margin credit to Tang Capital Partners, LP as and when required, to open or carry positions in the margin accounts, subject to applicable federal margin regulations, stock exchange rules and credit policies. In such instances, the positions held in the margin accounts are pledged as collateral security for the repayment of debit balances in the accounts. The margin accounts may from time to time have debit balances. Since multiple different securities are held in the margin accounts, it is not possible to determine the amounts, if any, of margin used to purchase the shares of Common Stock reported herein.

Item 4. Purpose of Transaction

The Reporting Persons purchased the Common Stock reported hereunder for investment purposes, and such purchases were made in the Reporting Persons' ordinary course of business. As with their other investments, the Reporting Persons continuously evaluate the Issuer, including but not limited to its businesses, results of operations, and prospects. In light of that ongoing evaluation, on March 14, 2023, Concentra, an affiliate of Tang Capital Partners, sent an acquisition proposal to the Issuer outlining the principal terms on which it would acquire all of the outstanding Common Stock of the Issuer (see Exhibit 2). The acquisition proposal provides that it is non-binding and subject to confirmatory diligence, as well as the execution of a definitive merger agreement. The Reporting Persons (excluding Concentra) are filing this Statement as an amendment to their Schedule 13G previously filed on March 6, 2023. The Reporting Persons intend to engage in discussions with the Issuer and its representatives concerning the acquisition proposal and the proposal contained therein and to enter into negotiations with the Issuer with respect thereto. There can be no certainty as to whether discussions will occur, or if they do, the outcome of such discussions.

While the Reporting Persons intend to pursue the proposal described in the acquisition proposal, in connection with their investment in the Issuer, the Reporting Persons may, subject to applicable law and regulation, further purchase, hold, vote, trade, dispose of or otherwise deal in the Common Stock at times, and in such manner, as they deem advisable to benefit from, among other things: (1) changes in the market prices of the shares of Common Stock; (2) changes in the Issuer's operations, business strategy or prospects; or (3) the sale or merger of the Issuer. To evaluate such alternatives, the Reporting Persons will continue to closely monitor the Issuer's operations, prospects, business development, management, competitive and strategic matters, capital structure, and prevailing market conditions, as well as other economic, securities markets and investment considerations. Consistent with their investment research methods and evaluation criteria, the Reporting Persons may discuss such matters with the management or Board of Directors of the Issuer, industry analysts, existing or potential strategic partners or competitors and investment and financing professionals. Such evaluations and discussions may materially affect, and result in, among other things, the Reporting Persons (1) consummating the transaction contemplated by the acquisition proposal; (2) modifying their ownership of the Common Stock; (3) exchanging information with the Issuer pursuant to appropriate confidentiality or similar agreements; (4) proposing changes in the Issuer's operations, governance or capitalization; or (5) pursuing one or more of the other actions described in Item 4 of this Schedule 13D.

Page 6 of 10 Pages

In addition to the information disclosed in this Statement, the Reporting Persons reserve the right to: (1) formulate other plans and proposals; (2) take any actions with respect to their investment in the Issuer, including any or all of the actions set forth in Item 4 of this Schedule 13D; and (3) subject to applicable law and regulation, acquire additional shares of Common Stock or dispose of some or all of the shares of Common Stock beneficially owned by them, in each case in the open market, through privately negotiated transactions or otherwise. The Reporting Persons may at any time reconsider and/or change their plans or proposals relating to the foregoing.

Item 5. Interest in Securities of the Issuer

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) Tang Capital Partners beneficially owns 5,300,087 shares of the Issuer's Common Stock. Tang Capital Partners shares voting and
dispositive power over such shares with Tang Capital Management and Kevin Tang.

Tang Capital Management beneficially owns 5,300,087 shares of the Issuer's Common Stock. Tang Capital Management shares voting and dispositive power over such shares with Tang Capital Partners and Kevin Tang.

Kevin Tang beneficially owns 5,300,087 shares of the Issuer's Common Stock. Kevin Tang shares voting and dispositive power over such shares with Tang Capital Partners and Tang Capital Management.

The percentages used herein are based on 52,140,277 shares of Common Stock outstanding as of March 7, 2023, as set forth in the Issuer's Annual Report filed on Form 10-K that was filed with the Securities and Exchange Commission on March 10, 2023.

Percent of Class:

---

| | |
|:---|:---|
| Tang Capital Partners | 10.2% |
| Tang Capital Management | 10.2% |
| Kevin Tang | 10.2% |
| Concentra | 0.0%<br>|

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) Number of shares as to which such person has:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) sole power to vote or to direct the vote:

---

| | |
|:---|:---|
| Tang Capital Partners | 0 shares |
| Tang Capital Management | 0 shares |
| Kevin Tang | 0 shares |
| Concentra | 0 shares  |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii) shared power to vote or to direct the vote:

---

| | |
|:---|:---|
| Tang Capital Partners | 5,300,087 shares |
| Tang Capital Management | 5,300,087 shares |
| Kevin Tang | 5,300,087 shares |
| Concentra | 0 shares  |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iii) sole power to dispose or to direct the disposition of:

---

| | |
|:---|:---|
| Tang Capital Partners | 0 shares |
| Tang Capital Management | 0 shares |
| Kevin Tang | 0 shares |
| Concentra | 0 shares  |

---

Page 7 of 10 Pages

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(iv) shared power to dispose or to direct the disposition of:

---

| | |
|:---|:---|
| Tang Capital Partners | 5,300,087 shares |
| Tang Capital Management | 5,300,087 shares |
| Kevin Tang | 5,300,087 shares |
| Concentra | 0 shares<br>|

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) The following describes all transactions in the Issuer's Common Stock that were effected during the past 60 days by the Reporting Persons:

---

| | | |
|:---|:---|:---|
| **<u>Transaction Date</u>** | **<u>Nature of Transaction</u>** | **<u>Price Per Share</u>** |
| 2/23/2023 | Purchase | $1.254666400<sup>1</sup> |
| 2/24/2023 | Purchase | $1.11189503<sup>2</sup> |
| 2/27/2023 | Purchase | $1.20144097<sup>3</sup> |
| 3/10/2023 | Purchase | $0.9739465<sup>4</sup> |
| 3/13/2023 | Purchase | $0.97240336<sup>5</sup> |
| 3/14/2023 | Purchase | $1.0220286<sup>6</sup> |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) No person other than a Reporting Person has the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, Common Stock beneficially owned by the Reporting Persons.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e) Not applicable.

Item 6. Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer

To the best of the knowledge of the Reporting Persons, there are no contracts, arrangements, understandings or relationships (legal or otherwise) among the Reporting Persons or between the Reporting Persons and any person with respect to any securities of the Issuer, including but not limited to transfer or voting of any of the securities, finder's fees, joint ventures, loan or option arrangements, puts or calls, guarantees of profits, division of profits or loss, or the giving or withholding of proxies.

_____________________________

<sup>1</sup> The prices reported are weighted-average prices. These shares were purchased in multiple transactions at prices ranging from $1.09 to $1.30. The Reporting Persons undertake to provide the Issuer, any security holder of the Issuer or the SEC staff, upon request, all information regarding the number of shares purchased at each price within the ranges set forth in Footnotes 1 through 6 herein.

<sup>2</sup> The price reported is a weighted-average price. These shares were purchased in multiple transactions at prices ranging from $1.05 to $1.17.

<sup>3</sup> The price reported is a weighted-average price. These shares were purchased in multiple transactions at prices ranging from $1.11 to $1.25.

<sup>4</sup> The price reported is a weighted-average price. These shares were purchased in multiple transactions at prices ranging from $0.86 to $1.05.

<sup>5</sup> The price reported is a weighted-average price. These shares were purchased in multiple transactions at prices ranging from $0.94 to $1.01.

<sup>6</sup> The price reported is a weighted-average price. These shares were purchased in multiple transactions at prices ranging from $1.00 to $1.02.

Page 8 of 10 Pages

Item 7. Material to Be Filed as Exhibits

Exhibit 1: Joint Filing Agreement by and among the Reporting Persons.

Exhibit 2: Acquisition Proposal, dated March 14, 2023, sent from Concentra to the Issuer.

Page 9 of 10 Pages

**SIGNATURE**

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: <u>March 14, 2023</u>

---

| | |
|:---|:---|
| TANG CAPITAL PARTNERS, LP | TANG CAPITAL PARTNERS, LP |
| By: Tang Capital Management, LLC, its General Partner | By: Tang Capital Management, LLC, its General Partner |
| By: | /s/ Kevin Tang |
|  | Kevin Tang, Manager |
| TANG CAPITAL MANAGEMENT, LLC | TANG CAPITAL MANAGEMENT, LLC |
| By: | /s/ Kevin Tang |
|  | Kevin Tang, Manager |
| /s/ Kevin Tang | /s/ Kevin Tang |
| Kevin Tang | Kevin Tang |
| CONCENTRA BIOSCIENCES, LLC | CONCENTRA BIOSCIENCES, LLC |
| By: | /s/ Kevin Tang |
|  | Kevin Tang, Chief Executive Officer |

---

Page 10 of 10 Pages

**EXHIBIT 1**

**JOINT FILING AGREEMENT**

In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree to the joint filing with all other Reporting Persons (as such term is defined in the Schedule 13D referred to below) on behalf of each of them of a statement on Schedule 13D (including amendments thereto) with respect to the common stock, par value $0.001, of Jounce Therapeutics, Inc., and that this Agreement be included as an Exhibit to such joint filing. The Agreement may be executed in any number of counterparts all of which taken together shall constitute one and the same instrument.

IN WITNESS WHEREOF, the undersigned hereby execute this Agreement this 14<sup>th</sup> day of March, 2023.

---

| | |
|:---|:---|
| TANG CAPITAL PARTNERS, LP | TANG CAPITAL PARTNERS, LP |
| By: Tang Capital Management, LLC, its General Partner | By: Tang Capital Management, LLC, its General Partner |
| By: | /s/ Kevin Tang |
|  | Kevin Tang, Manager |
| TANG CAPITAL MANAGEMENT, LLC | TANG CAPITAL MANAGEMENT, LLC |
| By: | /s/ Kevin Tang |
|  | Kevin Tang, Manager |
| /s/ Kevin Tang | /s/ Kevin Tang |
| Kevin Tang | Kevin Tang |
| CONCENTRA BIOSCIENCES, LLC | CONCENTRA BIOSCIENCES, LLC |
| By: | /s/ Kevin Tang |
|  | Kevin Tang, Chief Executive Officer |

---

**EXHIBIT 2**

**Concentra Biosciences, LLC** 

4747 Executive Drive, Suite 210 \| San Diego, CA 92121

March 14, 2023

Board of Directors<br> Jounce Therapeutics, Inc.<br> c/o Richard Murray, Chief Executive Officer<br> 780 Memorial Drive<br> Cambridge, Massachusetts 02139

Re: Acquisition Proposal

Dear Directors:

On behalf of Concentra Biosciences, LLC, I am pleased to submit this non-binding proposal to acquire 100% of the equity of Jounce Therapeutics, Inc. for $1.80 per share in cash, which represents an 80% premium to yesterday's closing price, plus a contingent value right ("CVR") representing the right to receive 80% of the net proceeds payable from any license or disposition of certain of Jounce's legacy programs<sup>1</sup> (the "CVR Products"). The terms of the CVR would be identical to those set forth in Jounce's Form 8-K filed February 23, 2023 reporting its proposed business combination with Redx Pharma plc.

Concentra has funds immediately available to execute this transaction through an arrangement with Tang Capital Partners, LP, its controlling shareholder. Furthermore, the management of Concentra has the expertise and resources to both maximize the value of the CVR for the benefit of legacy Jounce stockholders and responsibly wind down clinical study activities for the benefit of patients.

Our proposal is subject to limited confirmatory due diligence and is based on the availability of at least $130 million of cash and cash equivalents at closing, net of any tail and closing costs, as referenced in Jounce's February 23, 2023 press release discussing the Redx business combination. We expect that we can complete due diligence and negotiate a definitive merger agreement by March 31, 2023 and would be able to close our acquisition through a cash tender by early May 2023.

We believe that our proposal represents a compelling offer for Jounce stockholders. We hope that you share this view and look forward to discussing our proposal with you further. We would appreciate a response by 5pm ET on March 17, 2023, at which point this offer will expire.

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| Sincerely, |
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| Kevin Tang<br> Chief Executive Officer |

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<sup>1</sup> JTX-8064, vopratelimab, pimivalimab, JTX-1484 and JTX-2134