# EDGAR Filing Document

**Accession Number:** 0001599298
**File Stem:** 0001599298-25-000116
**Filing Date:** 2025-6
**Character Count:** 6708
**Document Hash:** 65bf6236f2455266afb4bac2d5f63013
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001599298-25-000116.hdr.sgml**: 20250617

**ACCESSION NUMBER**: 0001599298-25-000116

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 13

**CONFORMED PERIOD OF REPORT**: 20250612

**ITEM INFORMATION**: Submission of Matters to a Vote of Security Holders

**FILED AS OF DATE**: 20250617

**DATE AS OF CHANGE**: 20250617

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Summit Therapeutics Inc.
- **CENTRAL INDEX KEY:** 0001599298
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 371979717
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-36866
- **FILM NUMBER:** 251053453

**BUSINESS ADDRESS:**
- **STREET 1:** 601 BRICKELL KEY DRIVE
- **STREET 2:** SUITE 1000
- **CITY:** MIAMI
- **STATE:** FL
- **ZIP:** 33131
- **BUSINESS PHONE:** 305-203-2034

**MAIL ADDRESS:**
- **STREET 1:** 601 BRICKELL KEY DRIVE
- **STREET 2:** SUITE 1000
- **CITY:** MIAMI
- **STATE:** FL
- **ZIP:** 33131

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Summit Therapeutics plc
- **DATE OF NAME CHANGE:** 20150219

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Summit Corp plc
- **DATE OF NAME CHANGE:** 20140205

?xml version='1.0' encoding='ASCII'? smmt-20250612

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934**

Date of Report (Date of Earliest Event Reported): <u>June 12, 2025</u>

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| | | |
|:---|:---|:---|
| Summit Therapeutics Inc. | Summit Therapeutics Inc. | Summit Therapeutics Inc. |
| (Exact Name of Registrant as Specified in Its Charter) | (Exact Name of Registrant as Specified in Its Charter) | (Exact Name of Registrant as Specified in Its Charter) |
| Delaware | 001-36866 | 37-1979717 |
| (State or Other Jurisdiction<br>of Incorporation) | (Commission<br>File Number) | (IRS Employer<br>Identification No.) |
| 601 Brickell Key Drive, Suite 1000, Miami, FL | 601 Brickell Key Drive, Suite 1000, Miami, FL | 33131 |
| (Address of Principal Executive Offices) | (Address of Principal Executive Offices) | (Zip Code) |

---

Registrant's Telephone Number, Including Area Code: <u>(305) 203-2034</u>

Not applicable <br> (Former Name or Former Address, If Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (*see* General Instruction A.2. below):

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

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| | | |
|:---|:---|:---|
| Title of Each Class | Trading Symbol(s) | Name of Each Exchange on Which Registered |
| Common stock, $0.01 par value per share | SMMT | The Nasdaq Stock Market LLC |

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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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| | |
|:---|:---|
| **Item 5.07** | **Submission of Matters to a Vote of Security Holders.** |

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On June 12, 2025, Summit Therapeutics Inc. (the "Company") held its 2025 Annual Meeting of Stockholders (the "Annual Meeting"). The following matters were submitted to a vote of the Company's stockholders at the Annual Meeting: (i) the election of nine directors to serve until the Company's 2026 Annual Meeting of Stockholders and until their successors are duly elected and qualified; (ii) the ratification of the appointment of PricewaterhouseCoopers LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2025; and (iii) a non-binding advisory vote to approve the compensation paid to the Company's named executive officers.

Each of the matters submitted to a vote of the Company's stockholders at the Annual Meeting was approved by the requisite vote of the Company's stockholders in accordance with the recommendation of the Company's Board of Directors. Set forth below is the number of votes cast for, against or withheld, as well as the number of abstentions and broker non-votes, as to each such matter, including a separate tabulation with respect to each nominee for director, as applicable:

**Proposal 1**

Election of Directors

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| | | | |
|:---|:---|:---|:---|
| **Director Nominees** | **For** | **Withheld** | **Broker Non-Votes** |
| Robert W. Duggan | 613045226 | 26692 | 29651787 |
| Mahkam Zanganeh | 613581910 | 37546 | 29651787 |
| Manmeet Soni | 611431814 | 52326 | 29651787 |
| Kenneth A. Clark | 605079891 | 51558 | 29651787 |
| Robert Booth | 623298472 | 55319 | 29651787 |
| Alessandra Cesano | 617638155 | 54443 | 29651787 |
| Yu (Michelle) Xia | 610437122 | 54396 | 29651787 |
| Mostafa Ronaghi | 620904380 | 54324 | 29651787 |
| Jeff Huber | 623664686 | 53330 | 29651787 |

---

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| | | | | |
|:---|:---|:---|:---|:---|
| **Proposal 2** | **For** | **Against** | **Abstain** | **Broker Non-Votes** |
| Ratification of the appointment of PricewaterhouseCoopers LLP | 653,328,708 | 195,007 | 233,629 |  |

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| | | | | |
|:---|:---|:---|:---|:---|
| **Proposal 3** | **For** | **Against** | **Abstain** | **Broker Non-Votes** |
| Advisory vote to approve the compensation of named executive officers | 607,320,353 | 16,607,648 | 177,556 | 29,651,787 |

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.

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**SIGNATURE**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, hereunto duly authorized.

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| | | |
|:---|:---|:---|
| | **SUMMIT THERAPEUTICS INC.** | **SUMMIT THERAPEUTICS INC.** |
| Date: June 17, 2025 | By: | /s/ Manmeet S. Soni |
|  |  | Chief Operating Officer, Chief Financial Officer and Director |
|  |  | (Principal Financial Officer) |

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