# EDGAR Filing Document

**Accession Number:** 0001355064
**File Stem:** 0000910472-26-002713
**Filing Date:** 2026-2
**Character Count:** 30488
**Document Hash:** dc22faf7abf33d6287f1d3b7dc91b3f7
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000910472-26-002713.hdr.sgml**: 20260226

**ACCESSION NUMBER**: 0000910472-26-002713

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20251231

**FILED AS OF DATE**: 20260226

**DATE AS OF CHANGE**: 20260226

**PERIOD START**: 20260331

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MUTUAL FUND SERIES TRUST
- **CENTRAL INDEX KEY:** 0001355064

**ORGANIZATION NAME:**
- **EIN:** 000000000
- **STATE OF INCORPORATION:** OH
- **FISCAL YEAR END:** 0630

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-21872
- **FILM NUMBER:** 26683064

**BUSINESS ADDRESS:**
- **STREET 1:** C/O GEMINI FUND SERVICES LLC
- **STREET 2:** 4221 NORTH 203RD STREET, SUITE 100
- **CITY:** ELKHORN
- **STATE:** NE
- **ZIP:** 68022-3474
- **BUSINESS PHONE:** 631 549 1859

**MAIL ADDRESS:**
- **STREET 1:** C/O GEMINI FUND SERVICES LLC
- **STREET 2:** 4221 NORTH 203RD STREET, SUITE 100
- **CITY:** ELKHORN
- **STATE:** NE
- **ZIP:** 68022-3474

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** CATALYST FUNDS
- **DATE OF NAME CHANGE:** 20060303

## Series and Classes Contracts Data

### AlphaCentric Life Sciences and Healthcare Fund (Series ID: S000067055)

| Class ID   | Class Name                                             | Ticker Symbol   |
|:---|:---|:---|
| C000215729 | AlphaCentric Life Sciences and Healthcare Fund Class C | LYFCX           |
| C000215730 | AlphaCentric Life Sciences and Healthcare Fund Class I | LYFIX           |
| C000215731 | AlphaCentric Life Sciences and Healthcare Fund Class A | LYFAX           |

## Nport-Ex

---

| | | |
|:---|:---|:---|
| **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** | **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** | **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** |
| **SCHEDULE OF INVESTMENTS (Unaudited)** | **SCHEDULE OF INVESTMENTS (Unaudited)** | **SCHEDULE OF INVESTMENTS (Unaudited)** |
| **December 31, 2025** | **December 31, 2025** | **December 31, 2025** |
| **Shares** |  | **Fair Value** |
|  | **COMMON STOCKS — 93.6%** |  |
|  | **BIOTECH & PHARMA - 87.3%** |  |
| 2979 | AbbVie, Inc. | &nbsp;&nbsp;&nbsp; $680672 |
| 18782 | ADMA Biologics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 342584 |
| 13141 | Agios Pharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 357698 |
| 34912 | Aldeyra Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 180844 |
| 1295 | Alnylam Pharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 514957 |
| 2202 | Amgen, Inc. | &nbsp;&nbsp;&nbsp; 720737 |
| 10751 | Apogee Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 811485 |
| 47925 | Arbutus Biopharma Corporation<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 230519 |
| 1425 | Argenx S.E. - ADR<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 1198354 |
| 12435 | Arvinas, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 147479 |
| 3238 | Ascendis Pharma A/S - ADR<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 690471 |
| 21243 | AstraZeneca plc - ADR | &nbsp;&nbsp;&nbsp; 1952869 |
| 37693 | Avadel Pharmaceuticals plc<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 812284 |
| 6995 | Avidity Biosciences, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 504549 |
| 6088 | Axsome Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 1111912 |
| 3627 | Biogen, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 638316 |
| 5311 | BioNTech S.E. - ADR<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 505607 |
| 53625 | Black Diamond Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 130309 |
| 22020 | Catalyst Pharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 513947 |
| 19041 | Cullinan Oncology, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 197074 |
| 5311 | Cytokinetics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 337461 |
| 26812 | Day One Biopharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 249888 |
| 20262 | Design Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 190058 |
| 3756 | Disc Medicine, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 298264 |
| 14703 | Edgewise Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 364855 |
| 21761 | Gilead Sciences, Inc. | &nbsp;&nbsp;&nbsp; 2670945 |
| 4533 | Halozyme Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 305071 |
| 13471 | Incyte Corporation<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 1330531 |
| 7588 | Insmed, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 1320616 |
| 10880 | Intellia Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 97811 |
| 18523 | Ionis Pharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 1465355 |
| 3368 | Jazz Pharmaceuticals plc<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 572560 |
| 1813 | Krystal Biotech, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 446977 |
| 5035 | Kymera Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 391773 |

---

---

| | | |
|:---|:---|:---|
| **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** | **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** | **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** |
| **SCHEDULE OF INVESTMENTS (Unaudited) (Continued)** | **SCHEDULE OF INVESTMENTS (Unaudited) (Continued)** | **SCHEDULE OF INVESTMENTS (Unaudited) (Continued)** |
| **December 31, 2025** | **December 31, 2025** | **December 31, 2025** |
| **Shares** |  | **Fair Value** |
|  | **COMMON STOCKS — 93.6% (Continued)** |  |
|  | **BIOTECH & PHARMA - 87.3% (Continued)** |  |
| 28496 | MeiraGTx Holdings PLC<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; $226543 |
| 7383 | Neurocrine Biosciences, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 1047131 |
| 13731 | Newamsterdam Pharma Company N.V.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 481683 |
| 18134 | Nurix Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 344002 |
| 4404 | Nuvalent, Inc., Class A<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 442998 |
| 10880 | Oruka Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 329773 |
| 8549 | Protagonist Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 746670 |
| 6030 | Rapport Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 182950 |
| 67056 | Rezolute, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 158252 |
| 5052 | Rhythm Pharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 540766 |
| 45076 | Roivant Sciences Ltd.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 978149 |
| 13594 | Sanofi - ADR | &nbsp;&nbsp;&nbsp; 658765 |
| 9974 | Scholar Rock Holding Corporation<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 439355 |
| 2720 | Sionna Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 111901 |
| 6476 | Tectonic Therapeutic, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 135089 |
| 22667 | Trevi Therapeutics, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 283791 |
| 4663 | Vertex Pharmaceuticals, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 2114018 |
| 27590 | WaVe Life Sciences Ltd.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 469030 |
| 43392 | Xeris Biopharma Holdings, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 340627 |
|  |  | &nbsp;&nbsp; 32316325 |
|  | **HEALTH CARE FACILITIES & SERVICES - 2.8%** |  |
| 1295 | ICON plc<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 235975 |
| 777 | IQVIA Holdings, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 175144 |
| 75126 | MDxHealth S.A.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 268200 |
| 47796 | Personalis, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 380455 |
|  |  | &nbsp;&nbsp; 1059774 |
|  | **MEDICAL EQUIPMENT & DEVICES - 3.5%** |  |
| 4015 | Artivion, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 183124 |
| 7901 | Exact Sciences Corporation<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 802426 |
| 1295 | Natera, Inc.<sup>(a)</sup> | &nbsp;&nbsp;&nbsp; 296672 |
|  |  | &nbsp;&nbsp; 1282222 |
|  | **TOTAL COMMON STOCKS (Cost $27,013,701)** | &nbsp;&nbsp; 34658321 |

---

---

| | | |
|:---|:---|:---|
| **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** | **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** | **ALPHACENTRIC LIFE SCIENCES AND HEALTHCARE FUND (LYFAX, LYFCX, LYFIX)** |
| **SCHEDULE OF INVESTMENTS (Unaudited) (Continued)** | **SCHEDULE OF INVESTMENTS (Unaudited) (Continued)** | **SCHEDULE OF INVESTMENTS (Unaudited) (Continued)** |
| **December 31, 2025** | **December 31, 2025** | **December 31, 2025** |
| **Shares** |  | **Fair Value** |
|  | **SHORT-TERM INVESTMENTS — 6.5%** |  |
|  | **MONEY MARKET FUNDS - 6.5%** |  |
| 2 | Fidelity Investments Money Market Government Portfolio, Class I, 3.57%<sup>(b)</sup> | &nbsp;&nbsp;&nbsp; $2 |
| 2412797 | First American Treasury Obligations Fund, Class X, 3.68%<sup>(b)</sup> | &nbsp;&nbsp;&nbsp; 2412796 |
|  | **TOTAL MONEY MARKET FUNDS (Cost $2,412,798)** | &nbsp;&nbsp; 2412798 |
|  | **TOTAL INVESTMENTS - 100.1% (Cost $29,426,499)** | &nbsp;&nbsp;&nbsp; $37071119 |
|  | **LIABILITIES IN EXCESS OF OTHER ASSETS - (0.1)%** | &nbsp;&nbsp; (50967) |
|  | **NET ASSETS - 100.0%** | &nbsp;&nbsp; $37020152 |

---

---

| | |
|:---|:---|
| ADR | - American Depositary Receipt |
| A/S | - Anonim Sirketi |
| LTD | - Limited Company |
| PLC | - Public Limited Company |
| S.A. | - Société Anonyme |
| <sup>(a)</sup> | Non-income producing security. |
| <sup>(b)</sup> | Rate disclosed is the seven day effective yield as of December 31, 2025. |

---

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** MUTUAL FUND SERIES TRUST

- **b. Investment Company Act file number:** 811-21872

- **c. CIK number of Registrant:** 0001355064

- **d. LEI of Registrant:** 5493002ZGLQMLR4QMA96

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** C/O GEMINI FUND SERVICES LLC

  - **City:** ELKHORN

  - **State:** NE

  - **Foreign country:** US

  - **Zip / Postal Code:** 68022

  - **Telephone number:** 631-470-2600

**Item A.2. Information about the Series.**

- **a. Name of Series:** AlphaCentric Life Sciences and Healthcare Fund

- **b. EDGAR series identifier (if any):** S000067055

- **c. LEI of Series:** 549300XV4TMPQ6UX8179

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-03-31

- **b. Date as of which information is reported:** 2025-12-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $37103857.72

**Total Liabilities:** $83706.08

**Net Assets:** $37020151.64

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000215729 | 10.86%               | 8.36%                | -1.30%               |
| Class ID C000215730 | 10.94%               | 8.40%                | -1.20%               |
| Class ID C000215731 | 10.89%               | 8.42%                | -1.27%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $774583.96               | $2762458.81                                |
| Month 2  | $-45251.02               | $3013575.56                                |
| Month 3  | $604741.67               | $-1047218.76                               |

### Schedule of Portfolio Investments

| Name                                | Title            | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Adma Biologics Inc                  | ADMA BIOLOGICS I | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     18782 | NS      | $342583.68    | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc.                         | ABBVIE INC       | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |      2979 | NS      | $680671.71    | 1.84%             |  |  |  | No            |                  1 | On Loan: No      |
| Agios Pharmaceuticals Inc           | AGIOS PHARMACEUT | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     13141 | NS      | $357698.02    | 0.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Aldeyra Therapeutics Inc            | ALDEYRA THERAPEU | CUSIP: 01438T106<br>LEI: 529900HGKY864E4Y9014 | Long             | EC               | CORP              | US        |     34912 | NS      | $180844.16    | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Alnylam Pharmaceuticals Inc.        | ALNYLAM PHARMACE | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |      1295 | NS      | $514956.75    | 1.39%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc.                          | AMGEN INC        | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |      2202 | NS      | $720736.62    | 1.95%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc.            | APOGEE THERAPEUT | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     10751 | NS      | $811485.48    | 2.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp.             | ARBUTUS BIOPHARM | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | CA        |     47925 | NS      | $230519.25    | 0.62%             |  |  |  | No            |                  1 | On Loan: No      |
| Argenx SE                           | ARGENX SE - ADR  | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |      1425 | NS      | $1198353.75   | 3.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                         | ARVINAS INC      | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12435 | NS      | $147479.10    | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| Ascendis Pharma A/S                 | ASCENDIS PHA-ADR | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |      3238 | NS      | $690471.12    | 1.87%             |  |  |  | No            |                  1 | On Loan: No      |
| AstraZeneca PLC                     | ASTRAZENECA-ADR  | CUSIP: 046353108<br>LEI: PY6ZZQWO2IZFZC3IOL08 | Long             | EC               | CORP              | GB        |     21243 | NS      | $1952868.99   | 5.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Avidity Biosciences Inc.            | AVIDITY BIOSCIEN | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6995 | NS      | $504549.35    | 1.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc.            | AXSOME THERAPEUT | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |      6088 | NS      | $1111912.32   | 3.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                          | BIOGEN INC       | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |      3627 | NS      | $638315.73    | 1.72%             |  |  |  | No            |                  1 | On Loan: No      |
| BioNTech SE                         | BIONTECH SE-ADR  | CUSIP: 09075V102<br>LEI: 894500UZJ5LG1F8J1U58 | Long             | EC               | CORP              | DE        |      5311 | NS      | $505607.20    | 1.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Black Diamond Therapeutics Inc      | BLACK DIAMOND TH | CUSIP: 09203E105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     53625 | NS      | $130308.75    | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc.       | CATALYST PHARMAC | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |     22020 | NS      | $513946.80    | 1.39%             |  |  |  | No            |                  1 | On Loan: No      |
| Artivion Inc                        | ARTIVION INC     | CUSIP: 228903100<br>LEI: 549300YTKV8DMSMG6K81 | Long             | EC               | CORP              | US        |      4015 | NS      | $183124.15    | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc           | CULLINAN THERAPE | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     19041 | NS      | $197074.35    | 0.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                    | CYTOKINETICS INC | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |      5311 | NS      | $337460.94    | 0.91%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc.     | DAY ONE BIOPHARM | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     26812 | NS      | $249887.84    | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| Design Therapeutics Inc.            | DESIGN THERAPEUT | CUSIP: 25056L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     20262 | NS      | $190057.56    | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Disc Medicine Inc                   | DISC MEDICINE IN | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3756 | NS      | $298263.96    | 0.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc.          | EDGEWISE THERAPE | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     14703 | NS      | $364854.95    | 0.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Exact Sciences Corporation          | EXACT SCIENCES   | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |      7901 | NS      | $802425.56    | 2.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Fidelity Colchester Street Trust    | FID-MM GOVT-I    | CUSIP: 316175108<br>LEI: 549300SHPEJB1OPRCV46 | Long             | STIV             | RF                | US        |         2 | PA      | $1.60         | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| First American Funds Inc.           | FIRST AM-TR OB-X | CUSIP: 31846V328<br>LEI: 549300J5J5SJCZ9IA369 | Long             | STIV             | RF                | US        |   2412797 | PA      | $2412796.52   | 6.52%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc.                | GILEAD SCIENCES  | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |     21761 | NS      | $2670945.14   | 7.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc           | HALOZYME THERAPE | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |      4533 | NS      | $305070.90    | 0.82%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corporation.                 | INCYTE CORP      | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |     13471 | NS      | $1330530.67   | 3.59%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                          | INSMED INC       | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |      7588 | NS      | $1320615.52   | 3.57%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc           | INTELLIA THERAPE | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |     10880 | NS      | $97811.20     | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals, Inc.         | IONIS PHARMACEUT | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |     18523 | NS      | $1465354.53   | 3.96%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc.                 | IQVIA HOLDINGS I | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |       777 | NS      | $175143.57    | 0.47%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech Inc                 | KRYSTAL BIOTECH  | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |      1813 | NS      | $446977.02    | 1.21%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc             | KYMERA THERAPEUT | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5035 | NS      | $391773.35    | 1.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc.                         | NATERA INC       | CUSIP: 632307104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1295 | NS      | $296671.55    | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Neurocrine Biosciences Inc          | NEUROCRINE BIOSC | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |      7383 | NS      | $1047130.89   | 2.83%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvalent Inc                        | NUVALENT INC-A   | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4404 | NS      | $442998.36    | 1.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Nurix Therapeutics Inc.             | NURIX THERAPEUTI | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     18134 | NS      | $344001.98    | 0.93%             |  |  |  | No            |                  1 | On Loan: No      |
| Oruka Therapeutics Inc              | ORUKA THERAPEUTI | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |     10880 | NS      | $329772.80    | 0.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Personalis Inc                      | PERSONALIS INC   | CUSIP: 71535D106<br>LEI: 549300EZ2NYFK7H0US48 | Long             | EC               | CORP              | US        |     47796 | NS      | $380456.16    | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc        | PROTAGONIST THER | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      8549 | NS      | $746669.66    | 2.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Rapport Therapeutics Inc            | RAPPORT THERAPEU | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6030 | NS      | $182950.20    | 0.49%             |  |  |  | No            |                  1 | On Loan: No      |
| Rezolute Inc                        | REZOLUTE INC     | CUSIP: 76200L309<br>LEI: 549300T05L48T72P2G08 | Long             | EC               | CORP              | US        |     67056 | NS      | $158252.16    | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc          | RHYTHM PHARMACEU | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |      5052 | NS      | $540766.08    | 1.46%             |  |  |  | No            |                  1 | On Loan: No      |
| Sanofi SA                           | SANOFI-ADR       | CUSIP: 80105N105<br>LEI: 549300E9PC51EN656011 | Long             | EC               | CORP              | FR        |     13594 | NS      | $658765.24    | 1.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Scholar Rock Holding Corp.          | SCHOLAR ROCK HOL | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |      9974 | NS      | $439354.70    | 1.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Sionna Therapeutics Inc.            | SIONNA THERAPEUT | CUSIP: 829401108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2720 | NS      | $111900.80    | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Tectonic Therapeutic Inc            | TECTONIC THERAPE | CUSIP: 878972108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6476 | NS      | $135089.36    | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Trevi Therapeutics Inc              | TREVI THERAPEUTI | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22667 | NS      | $283790.84    | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Incorporated | VERTEX PHARM     | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |      4663 | NS      | $2114017.68   | 5.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc        | XERIS BIOPHARMA  | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     43392 | NS      | $340627.20    | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| MDXHealth SA                        | MDXHEALTH        | CUSIP: B5950S113<br>LEI: 549300J3MG9F9B5FY646 | Long             | EC               | CORP              | BE        |     75126 | NS      | $268199.82    | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Avadel Pharmaceuticals PLC          | AVADEL PHARMACEU | CUSIP: G29687103<br>LEI: 549300E27PTSG2RHC762 | Long             | EC               | CORP              | IE        |     37693 | NS      | $812284.15    | 2.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Icon PLC                            | ICON PLC         | CUSIP: G4705A100<br>LEI: 6354008SRQGEMC4XFI67 | Long             | EC               | CORP              | IE        |      1295 | NS      | $235974.90    | 0.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC            | JAZZ PHARMACEUTI | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | IE        |      3368 | NS      | $572560.00    | 1.55%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings PLC               | MEIRAGTX HOLDING | CUSIP: G59665102<br>LEI: 54930007YV6NYIOGFZ57 | Long             | EC               | CORP              | KY        |     28496 | NS      | $226543.20    | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                | ROIVANT SCIENCES | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | BM        |     45076 | NS      | $978149.20    | 2.64%             |  |  |  | No            |                  1 | On Loan: No      |
| NewAmsterdam Pharma Company NV      | NEWAMSTERDAM PHA | CUSIP: N62509109<br>LEI: 984500B6549TF6E14D36 | Long             | EC               | CORP              | NL        |     13731 | NS      | $481683.48    | 1.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Wave Life Sciences Ltd.             | WAVE LIFE SCIENC | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | SG        |     27590 | NS      | $469030.00    | 1.27%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-01-28

**Name of Applicant:** MUTUAL FUND SERIES TRUST

**Signature:** Erik Naviloff

**Name of Signer:** Erik Naviloff

**Title:** Treasurer