# EDGAR Filing Document

**Accession Number:** 0001734005
**File Stem:** 0001213900-25-112134
**Filing Date:** 2025-11
**Character Count:** 2706
**Document Hash:** 3b6087110aa11f360d0ad79061849552
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001213900-25-112134.hdr.sgml**: 20251118

**ACCESSION NUMBER**: 0001213900-25-112134

**CONFORMED SUBMISSION TYPE**: DEL AM

**PUBLIC DOCUMENT COUNT**: 1

**FILED AS OF DATE**: 20251118

**DATE AS OF CHANGE**: 20251118

**EFFECTIVENESS DATE**: 20251118

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Aptorum Group Ltd
- **CENTRAL INDEX KEY:** 0001734005
- **STANDARD INDUSTRIAL CLASSIFICATION:** MEASURING & CONTROLLING DEVICES, NEC [3829]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 000000000
- **STATE OF INCORPORATION:** E9
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DEL AM
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-291593
- **FILM NUMBER:** 251495178

**BUSINESS ADDRESS:**
- **STREET 1:** 17 HANOVER SQUARE
- **CITY:** LONDON
- **STATE:** X0
- **ZIP:** W1S 1BN
- **BUSINESS PHONE:** 852 3953 7700

**MAIL ADDRESS:**
- **STREET 1:** 17 HANOVER SQUARE
- **CITY:** LONDON
- **STATE:** X0
- **ZIP:** W1S 1BN

**Aptorum Group Limited**

**17 Hanover Square**

**London W1S 1BN, United Kingdom**

**+44 20 80929299**

***VIA EDGAR***

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549

November 18, 2025

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| | |
|:---|:---|
| **Re:** | **Aptorum Group Limited** |
|  | **Registration Statement on Form F-1** |
|  | **Filed on November 17, 2025** |
|  | **File No. 333-291593** |

---

Ladies and Gentlemen:

Reference is made to the Registration Statement on Form F-1 (File No. 333-291593) filed by Aptorum Group Limited on November 17, 2025 (the "Registration Statement").

Pursuant to Rule 473(c) of the Securities Act of 1933 (the "Act"), the following delaying amendment, prescribed by Rule 473(a) of the Act, is hereby incorporated into the facing page of the Registration Statement:

"**The registrant hereby amends this Registration Statement on such date or dates as may be necessary to delay its effective date until the registrant shall file a further amendment which specifically states that this Registration Statement shall thereafter become effective in accordance with Section 8(a) of the Securities Act of 1933, as amended, or until the Registration Statement shall become effective on such date as the Commission, acting pursuant to said Section 8(a), may determine."**

Should you have any questions regarding the Registration Statement, please feel free to contact the undersigned at +44 20 80929299.

---

| | |
|:---|:---|
| Sincerely, | Sincerely, |
| By: | */s/ Ian Huen* |
| Name: | Ian Huen |
| Title: | Chief Executive Officer |

---

cc: Louis Taubman, Esq. <br> Hunter Taubman Fischer & Li LLC