# EDGAR Filing Document

**Accession Number:** 0001095435
**File Stem:** 0001171843-23-001307
**Filing Date:** 2023-3
**Character Count:** 224364
**Document Hash:** 38bf8b37faccb86c0071dd299a549a89
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001171843-23-001307.hdr.sgml**: 20241204

**ACCESSION NUMBER**: 0001171843-23-001307

**CONFORMED SUBMISSION TYPE**: 6-K

**PUBLIC DOCUMENT COUNT**: 99

**CONFORMED PERIOD OF REPORT**: 20221231

**FILED AS OF DATE**: 20230301

**DATE AS OF CHANGE**: 20230301

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** PORTAGE BIOTECH INC.
- **CENTRAL INDEX KEY:** 0001095435
- **STANDARD INDUSTRIAL CLASSIFICATION:** CRUDE PETROLEUM & NATURAL GAS [1311]
- **IRS NUMBER:** 000000000
- **STATE OF INCORPORATION:** A6
- **FISCAL YEAR END:** 0331

**FILING VALUES:**
- **FORM TYPE:** 6-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-40086
- **FILM NUMBER:** 23694069

**BUSINESS ADDRESS:**
- **STREET 1:** 6 ADELAIDE ST. EAST
- **STREET 2:** SUITE 300
- **CITY:** TORONTO
- **STATE:** A6
- **ZIP:** M5C 1H6
- **BUSINESS PHONE:** 416-737-7600

**MAIL ADDRESS:**
- **STREET 1:** 6 ADELAIDE ST. EAST
- **STREET 2:** SUITE 300
- **CITY:** TORONTO
- **STATE:** A6
- **ZIP:** M5C 1H6

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** BONTAN CORP INC
- **DATE OF NAME CHANGE:** 20030421

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** DEALCHECK COM INC
- **DATE OF NAME CHANGE:** 19990921

?xml version="1.0" encoding="utf-8"?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549**

**FORM 6-K**

**REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16**

**UNDER THE SECURITIES EXCHANGE ACT OF 1934**

**For the month of March 2023**

Commission File Number: **001-40086**

**<u>Portage Biotech Inc.</u>**

(Translation of registrant's name into English)

**<u>Clarence Thomas Building, P.O. Box 4649, Road Town, Tortola, British Virgin Islands, VG1110</u>**

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒ Form 40-F ☐

**EXHIBITS**

---

| | |
|:---|:---|
| **Exhibit No.** | **Exhibit** |
| [99.1](exh_991.htm) | [Unaudited Condensed Consolidated Interim Financial Statements for the three and nine months ended December 31, 2022. Unaudited - Prepared by Management as of March 1, 2023.](exh_991.htm) |
| [99.2](exh_992.htm) | [Management's Discussion and Analysis for the three and nine months ended December 31, 2022.](exh_992.htm) |

---

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: March 1, 2023

**PORTAGE BIOTECH INC.**

---

| | |
|:---|:---|
| By: | /s/ Allan Shaw |
|  | Allan Shaw |
|  | Chief Financial Officer |

---

## Exhibit 99.1

?xml version="1.0" encoding="utf-8"?

**Exhibit 99.1**

**Portage Biotech Inc.**

**Condensed Consolidated Interim Financial Statements**

**For the Three and Nine Months Ended December 31, 2022**

**(Unaudited – Prepared by Management as of March 1, 2023)**

**(U.S. Dollars)**

**Portage Biotech Inc.**

**Condensed Consolidated Interim Financial Statements**

---

| | |
|:---|:---|
| **Index** | **Page** |
| Notice to Reader | F-1 |
| Condensed Consolidated Interim Statements of Financial Position |  |
| As of December 31, 2022 (Unaudited) and March 31, 2022 | F-2 |
| Condensed Consolidated Interim Statements of Operations and Other Comprehensive Income (Loss) (Unaudited) |  |
| Three and nine months ended December 31, 2022 and 2021 | F-3 |
| Condensed Consolidated Interim Statements of Changes in Shareholders' Equity (Unaudited) |  |
| Nine months ended December 31, 2022 and 2021 | F-4 |
| Condensed Consolidated Interim Statements of Cash Flows (Unaudited) |  |
| Nine months ended December 31, 2022 and 2021 | F-5 |
| Notes to Condensed Consolidated Interim Financial Statements | F-6 to F-37 |

---

**NOTICE TO READER OF CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS** 

The condensed consolidated interim financial statements of Portage Biotech Inc. are comprised of the condensed consolidated statements of financial position as of December 31, 2022 and March 31, 2022, the condensed consolidated interim statements of operations and other comprehensive income (loss) for the three and nine months ended December 31, 2022 and 2021 and the statements of equity and cash flows for each of the nine months ended December 31, 2022 and 2021 and are the responsibility of Portage Biotech Inc.'s management.

The condensed consolidated interim financial statements of Portage Biotech Inc. have been prepared by Portage Biotech Inc.'s management and include the selection of appropriate accounting principles, judgments and estimates necessary to prepare these condensed consolidated interim financial statements in accordance with International Financial Reporting Standards.

---

| | |
|:---|:---|
| /s/ Allan Shaw | /s/ Ian Walters |
| Allan Shaw, CFO | Ian Walters, MD, Chairman of the Board and Chief Executive Officer |
| DATE: March 1, 2023 |  |

---

**Portage Biotech Inc.**

**Condensed Consolidated Interim Statements of Financial Position**

**(U.S. Dollars in thousands)**

**(Unaudited – see Notice to Reader dated March 1, 2023)**

---

| | | | |
|:---|:---|:---|:---|
| **As of,** | **Note** | **December 31,<br> 2022** | **March 31,<br> 2022** |
|  |  |  | (Audited) |
| **Assets** |  |  |  |
| **Current assets** |  |  |  |
| &nbsp;&nbsp;&nbsp;Cash and cash equivalents |  | $**13104** | $23352 |
| &nbsp;&nbsp;&nbsp;Prepaid expenses and other receivables | **5** | **1786** | 1480 |
| &nbsp;&nbsp;&nbsp;Convertible note receivable | **6** | **642** | – |
| **Total current assets** |  | **15532** | 24832 |
| **Long-term assets** |  |  |  |
| &nbsp;&nbsp;&nbsp;Investment in associate | **6** | **1405** | 1673 |
| &nbsp;&nbsp;&nbsp;Investment in private company | **7** | **3363** | 7409 |
| &nbsp;&nbsp;&nbsp;Goodwill | **8, 9** | **43862** | 43324 |
| &nbsp;&nbsp;&nbsp;In-process research and development | **8, 10** | **145588** | 117388 |
| &nbsp;&nbsp;&nbsp;Deferred commitment fee | **17** | **894** |  |
| &nbsp;&nbsp;&nbsp;Other assets, including equipment, net |  | **39** | 36 |
| **Total long-term assets** |  | **195151** | 169830 |
| **Total assets** |  | $**210683** | $194662 |
| **Liabilities and Equity** |  |  |  |
| **Current liabilities** |  |  |  |
| &nbsp;&nbsp;&nbsp;Accounts payable and accrued liabilities |  | $**2422** | $750 |
| &nbsp;&nbsp;&nbsp;Warrant liability | **13** | **–** | 33 |
| **Total current liabilities** |  | **2422** | 783 |
| **Non-current liabilities** |  |  |  |
| &nbsp;&nbsp;&nbsp;Deferred tax liability | **10, 12** | **25515** | 28445 |
| &nbsp;&nbsp;&nbsp;Deferred purchase price payable - Tarus | **8, 19** | **8876** |  |
| &nbsp;&nbsp;&nbsp;Deferred obligation - iOx milestone | **18, 19** | **5568** | – |
| **Total non-current liabilities** |  | **39959** | 28445 |
| **Total liabilities** |  | **42381** | 29228 |
| **Shareholders' Equity** |  |  |  |
| &nbsp;&nbsp;&nbsp;Capital stock | **14** | **216630** | 158324 |
| &nbsp;&nbsp;&nbsp;Stock option reserve | **15** | **20542** | 16928 |
| &nbsp;&nbsp;&nbsp;Accumulated other comprehensive (loss) income |  | **(3059)** | 958 |
| &nbsp;&nbsp;&nbsp;Accumulated deficit |  | **(65168)** | (55005) |
| **Total equity attributable to owners of the Company** |  | **168945** | 121205 |
| **Non-controlling interest** | **21** | **(643)** | 44229 |
| **Total equity** |  | **168302** | 165434 |
| **Total liabilities and equity** |  | $**210683** | $194662 |
| **Commitments and Contingent Liabilities (Note 17)** |  |  |  |

---

**The accompanying notes are an integral part of these condensed consolidated interim financial statements.**

**Portage Biotech Inc.**

**Condensed Consolidated Interim Statements of Operations and Other Comprehensive Income (Loss)**

**(U.S. Dollars in thousands, except per share amounts)**

**(Unaudited – see Notice to Reader dated March 1, 2023)**

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
|  | **Note** | **Three months ended<br> December 31,** | **Three months ended<br> December 31,** | **Nine months ended<br> December 31,** | **Nine months ended<br> December 31,** |
|  |  | **2022** | 2021 | **2022** | **2021** |
|  |  | **In 000'$** | In 000'$ | **In 000'$** | In 000'$ |
| **Expenses** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Research and development |  | $**2535** | $1928 | $**5976** | $4804 |
| &nbsp;&nbsp;&nbsp;General and administrative expenses |  | **2224** | 2241 | **6523** | 6288 |
| **Loss from operations** |  | **(4759)** | (4169) | **(12499)** | (11092) |
| &nbsp;&nbsp;&nbsp;Change in fair value of deferred purchase price payable - Tarus and deferred obligation - iOx milestone | **8, 18** | **(498)** |  | **(428)** |  |
| &nbsp;&nbsp;&nbsp;Share of loss in associate accounted for using equity method | **6** | **(152)** | (261) | **(268)** | (363) |
| &nbsp;&nbsp;&nbsp;Change in fair value of warrant liability | **13** | **8** | 342 | **33** | 726 |
| &nbsp;&nbsp;&nbsp;Foreign exchange transaction gain (loss) | **10, 12** | **50** |  | **(60)** |  |
| &nbsp;&nbsp;&nbsp;Depreciation expense |  | **(1)** |  | **(1)** |  |
| &nbsp;&nbsp;&nbsp;Interest income |  | **50** |  | **115** |  |
| &nbsp;&nbsp;&nbsp;Interest expense |  | **–** | (1) | **(9)** | (42) |
| **Loss before provision for income taxes** |  | **(5302)** | (4089) | **(13117)** | (10771) |
| &nbsp;&nbsp;&nbsp;Income tax (expense) benefit | **12** | **(2199)** | (117) | **2906** | 465 |
| **Net loss** |  | **(7501)** | (4206) | **(10211)** | (10306) |
| **Other comprehensive income (loss)** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Net unrealized loss on investments | **7** | **(4017)** | – | **(4017)** | – |
| **Total comprehensive loss for period** |  | $**(11518)** | $(4206) | $**(14228)** | $(10306) |
| **Net loss attributable to:** |  |  |  |  |  |
| **Owners of the Company** |  | $**(7485)** | $(3512) | $**(10163)** | $(9553) |
| **Non-controlling interest** | **21** | **(16)** | (694) | **(48)** | (753) |
| **Net loss** |  | $**(7501)** | $(4206) | $**(10211)** | $(10306) |
| **Comprehensive loss attributable to:** |  |  |  |  |  |
| &nbsp;&nbsp;&nbsp;**Owners of the Company** |  | $**(11502)** | $(3512) | $**(14180)** | $(9553) |
| &nbsp;&nbsp;&nbsp;**Non-controlling interest** | **21** | **(16)** | (694) | **(48)** | (753) |
| **Total comprehensive loss for period** |  | $**(11518)** | $(4206) | $**(14228)** | $(10306) |
| **Loss per share** | **16** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Basic and diluted |  | $**(0.44)** | $(0.26) | $**(0.65)** | $(0.74) |
| **Weighted average shares outstanding** | **16** |  |  |  |  |
| &nbsp;&nbsp;&nbsp;Basic and diluted |  | **17039** | 13344 | **15719** | 12966 |

---

**The accompanying notes are an integral part of these condensed consolidated interim financial statements.**

**Portage Biotech Inc.**

**Condensed Consolidated Interim Statements of Changes in Shareholders' Equity**

**For the Nine Months Ended December 31, 2022 and 2021**

**(U.S. Dollars)**

**(Unaudited – see Notice to Reader dated March 1, 2023)**

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
|  | **Number of Shares** | **Capital Stock** | **Stock Option Reserve** | **Accumulated <br>Other Comprehensive (Loss) Income** | **Retained Earnings<br> (Accumulated Deficit)** | **Equity Attributable to Owners of Company** | **Non-<br> Controlling Interest** | **Total Equity** |
|  | **In '000'** | **In '000'$** | **In '000'$** | **In '000'$** | **In '000'$** | **In '000'$** | **In '000'$** | **In '000'$** |
| **Balance, April 1, 2022** | **13349** | $**158324** | $**16928** | $**958** | $**(55005)** | $**121205** | $**44229** | $**165434** |
| **Share-based compensation expense** | **–** | **–** | **3614** | **–** | **–** | **3614** | **–** | **3614** |
| **Shares issued in Tarus acquisition** | **2426** | **17200** | **–** | **–** | **–** | **17200** | **–** | **17200** |
| **Shares issued in iOx exchange** | **1070** | **9737** | **–** | **–** | **–** | **9737** | **(9737)** | **–** |
| **Deferred obligation - iOx milestone** | **–** | **–** | **–** | **–** | **–** | **–** | **(5478)** | **(5478)** |
| **Excess of non-controlling interest acquired over consideration - iOx** | **–** | **29609** | **–** | **–** | **–** | **29609** | **(29609)** | **–** |
| **Shares issued to Lincoln for commitment fee under Committed Purchase Agreement** | **94** | **900** | **–** | **–** | **–** | **900** | **–** | **900** |
| **Shares issued under ATM** | **88** | **604** | **–** | **–** | **–** | **604** | **–** | **604** |
| **Purchase of shares issued under Committed Purchase Agreement** | **30** | **190** | **–** | **–** | **–** | **190** | **–** | **190** |
| **Share issuance costs** | **–** | **(24)** | **–** | **–** | **–** | **(24)** | **–** | **(24)** |
| **Shares issued or accrued for services** | **13** | **90** | **–** | **–** | **–** | **90** | **–** | **90** |
| **Net unrealized loss on investments** | **–** | **–** | **–** | **(4017)** | **–** | **(4017)** | **–** | **(4017)** |
| **Net loss for period** | **–** | **–** | **–** | **–** | **(10163)** | **(10163)** | **(48)** | **(10211)** |
| **Balance, December 31, 2022** | **17070** | $**216630** | $**20542** | $**(3059)** | $**(65168)** | $**168945** | $**(643)** | $**168302** |
| Balance, April 1, 2021 | 12084 | $130649 | $7977 | $958 | $(38135) | $101449 | $46153 | $147602 |
| Share-based compensation expense |  |  | 6248 |  |  | 6248 | 191 | 6439 |
| Shares issued under ATM | 91 | 2643 |  |  |  | 2643 |  | 2643 |
| Shares issued under public offering | 1150 | 26450 |  |  |  | 26450 |  | 26450 |
| Share issuance costs |  | (1877) |  |  |  | (1877) |  | (1877) |
| Shares issued or accrued for services | 4 | 90 |  |  |  | 90 |  | 90 |
| Warrants exercised | 16 | 339 |  |  |  | 339 |  | 339 |
| Exchange of notes payable and accrued interest for iOx shares |  |  |  |  |  |  | 184 | 184 |
| Net loss for period | – | – | – | – | (9553) | (9553) | (753) | (10306) |
| Balance, December 31, 2021 | 13345 | $158294 | $14225 | $958 | $(47688) | $125789 | $45775 | $171564 |

---

**The accompanying notes are an integral part of these condensed consolidated interim financial statements.**

**Portage Biotech Inc.**

**Condensed Consolidated Interim Statements of Cash Flows**

**For the Nine Months Ended December 31, 2022 and 2021**

**(U.S. Dollars in thousands)**

**(Unaudited – see Notice to Reader dated March 1, 2023)**

---

| | | |
|:---|:---|:---|
|  | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** |
|  | **2022** | **2021** |
| **Cash flows from operating activities:** |  |  |
| &nbsp;&nbsp;&nbsp;Net loss for the period | $**(10211)** | $(10306) |
| **Adjustments for non-cash items:** |  |  |
| &nbsp;&nbsp;&nbsp;Share-based compensation expense | **3614** | 6439 |
| &nbsp;&nbsp;&nbsp;Decrease in deferred tax liability | **(2930)** | (444) |
| &nbsp;&nbsp;&nbsp;Change in fair value of warrant liability | **(33)** | (726) |
| &nbsp;&nbsp;&nbsp;Change in fair value of deferred purchase price payable - Tarus and deferred obligation - iOx milestone | **428** |  |
| &nbsp;&nbsp;&nbsp;Fair value of shares issued for services | **90** | 90 |
| &nbsp;&nbsp;&nbsp;Share of loss in associate | **268** | 363 |
| &nbsp;&nbsp;&nbsp;Foreign exchange transaction gain | **(15)** |  |
| &nbsp;&nbsp;&nbsp;Depreciation | **1** |  |
| **Changes in operating working capital:** |  |  |
| &nbsp;&nbsp;&nbsp;Accounts receivable | **25** | 385 |
| &nbsp;&nbsp;&nbsp;Prepaid expenses and other receivables | **(354)** | 1286 |
| &nbsp;&nbsp;&nbsp;Other assets | **24** | (144) |
| &nbsp;&nbsp;&nbsp;Accounts payable and accrued liabilities | **1671** | (1486) |
| &nbsp;&nbsp;&nbsp;Other | **30** | 30 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Net cash used in operating activities** | **(7392)** | (4513) |
| **Cash flows from investing activities:** |  |  |
| &nbsp;&nbsp;&nbsp;Purchase of convertible note receivable | **(614)** |  |
| &nbsp;&nbsp;&nbsp;Purchase of equipment | **(3)** | – |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Net cash used in investing activities** | **(617)** | – |
| **Cash flows from financing activities:** |  |  |
| &nbsp;&nbsp;&nbsp;Repayment of notes payable assumed in Tarus acquisition | **(2000)** |  |
| &nbsp;&nbsp;&nbsp;Repayment of milestone obligation assumed in Tarus acquisition | **(1009)** |  |
| &nbsp;&nbsp;&nbsp;Proceeds from shares issued under ATM and Committed Purchase | **794** |  |
| &nbsp;&nbsp;&nbsp;Proceeds from shares issued under registered offering | **–** | 29093 |
| &nbsp;&nbsp;&nbsp;Share issuance costs | **(24)** | (1852) |
| &nbsp;&nbsp;&nbsp;Proceeds from exercise of stock purchase warrants | **–** | 105 |
| &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**Net cash (used in) provided by financing activities** | **(2239)** | 27346 |
| **(Decrease) increase in cash and cash equivalents during period** | **(10248)** | 22833 |
| **Cash and cash equivalents at beginning of period** | **23352** | 2770 |
| **Cash and cash equivalents at end of period** | $**13104** | $25603 |
| **Supplemental disclosure of cash flow information:** |  |  |
| &nbsp;&nbsp;&nbsp;Cash paid for interest | $**–** | $19 |
| &nbsp;&nbsp;&nbsp;Increase in accounts payable for stock issuance costs | $**–** | $25 |
| **Supplemental disclosure of non-cash investing and financing activities:** |  |  |
| &nbsp;&nbsp;&nbsp;Fair value of shares issued for Tarus | $**17200** | $– |
| &nbsp;&nbsp;&nbsp;Fair value of shares issued for non-controlling interest purchase of iOx | $**9737** | $– |
| &nbsp;&nbsp;&nbsp;Fair value of deferred purchase price payable-Tarus | $**8538** | $– |
| &nbsp;&nbsp;&nbsp;Fair value of deferred obligation - iOx milestone | $**5478** | $– |
| &nbsp;&nbsp;&nbsp;Liabilities assumed in Tarus acquisition | $**3000** | $– |
| &nbsp;&nbsp;&nbsp;Fair value of shares issued for commitment fees - Committed Purchase | $**900** | $– |
| &nbsp;&nbsp;&nbsp;Exchange of iOx shares for settlement of notes payable, accrued interest and warrants | $**–** | $184 |

---

**The accompanying notes are an integral part of these condensed consolidated interim financial statements.**

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 1. NATURE OF OPERATIONS**

Portage Biotech Inc. (the "Company" or "Portage") is incorporated in the British Virgin Islands ("BVI") with its registered office located at Clarence Thomas Building, P.O. Box 4649, Road Town, Tortola, BVI. Its USA agent, Portage Development Services Inc. ("PDS"), is located at 61 Wilton Road, Westport, CT, 06880, USA.

The Company is a foreign private issuer under the Securities and Exchange Commission (the "SEC") rules. It is also a reporting issuer under the securities legislation of the provinces of Ontario and British Columbia. Its ordinary shares were listed on the Canadian Securities Exchange ("CSE") under the symbol "PBT.U". On February 25, 2021, the ordinary shares of the Company began trading on the NASDAQ Capital Market ("NASDAQ") under the symbol "PRTG". As the principal market for the Company's ordinary shares is NASDAQ, the Company voluntarily delisted from the CSE on April 23, 2021.

Portage is a clinical-stage immuno-oncology company advancing therapies that target known checkpoint resistance pathways to improve long-term treatment response and quality of life in patients with evasive cancers. Portage's access to next-generation technologies coupled with a deep understanding of biological mechanisms enable the identification of clinical therapies and product development strategies that accelerate these medicines through the translational pipeline. Portage's portfolio consists of six diverse platforms, with lead programs including invariant natural killer T-cell ("iNKT") agonists and a suite of treatments targeting the adenosine pathway. Additional programs leverage delivery by intratumorals, nanoparticles, liposomes, aptamers, and virus-like particles. Within these six platforms, Portage has 16 products currently in development with multiple clinical readouts expected through the end of 2023.

On August 13, 2018, the Company reached a definitive agreement to acquire 100% of SalvaRx Limited ("SalvaRx") in exchange for 8,050,701 ordinary shares of the Company (the "SalvaRx Acquisition"). The SalvaRx Acquisition was completed on January 8, 2019 (the "Acquisition Date") upon receiving shareholder and regulatory approval. In connection with the SalvaRx Acquisition, the Company acquired interests in SalvaRx's five research and development invested entities and subsidiaries: iOx Therapeutics Ltd. ("iOx"), Nekonal Oncology Limited ("Nekonal"), Intensity Therapeutics, Inc. ("Intensity"), Saugatuck Therapeutics, Ltd. ("Saugatuck") and Rift Biotherapeutics Inc. ("Rift"). The Company also acquired an option in Nekonal SARL, a Luxembourg-based company holding intellectual property rights for therapeutics and diagnostics in the field of autoimmune disorders and oncology, to participate in the funding of its autoimmune programs. During fiscal 2021, the Company abandoned its interests in Nekonal and Nekonal SARL.

**NOTE 2. LIQUIDITY**

As of December 31, 2022, the Company had cash and cash equivalents of approximately $13.1 million and total current liabilities of approximately $2.4 million. For the nine months ended December 31, 2022, the Company is reporting a net loss of approximately $10.2 million and cash used in operating activities of approximately $7.4 million. As of January 31, 2023, the Company had approximately $13.2 million of cash and cash equivalents on hand. The Company believes its current cash resources, including its access to the ATM and Committed Purchase (each as defined below, are sufficient to fund operations for at least 13 months from March 1, 2023, the date when the Company's management prepared the Company's condensed consolidated interim financial statements for the three and nine months ended December 31, 2022.

Portage filed a shelf registration statement and prospectus with the SEC under which it may sell shares, debt securities, warrants and units in one or more offerings from time to time, which became effective on March 8, 2021 ("Registration Statement" or "Prospectus"). In connection with the Registration Statement, Portage has filed with the SEC:

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 2. LIQUIDITY *(Cont'd)***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a base prospectus, which covers the offering, issuance and sale by Portage of up to $200,000,000 in the aggregate of the securities
identified above from time to time in one or more offerings;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a prospectus supplement covering the offer, issuance and sale by Portage in an "at the market" (the "ATM")
offering of up to a maximum aggregate offering price of up to $50,000,000 of Portage's ordinary shares that may be issued and sold
from time to time under a Controlled Equity Offering Sales Agreement dated February 24, 2021 (the "Sales Agreement"), with
Cantor Fitzgerald & Co., the sales agent ("Cantor Fitzgerald");

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a prospectus supplement dated June 24, 2021, for the offer, issuance and sale by Portage of 1,150,000 ordinary shares for gross proceeds
of approximately $26.5 million in a firm commitment underwriting with Cantor Fitzgerald; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a prospectus supplement dated August 19, 2022, for the resale of up to $30,000,000 of Portage's ordinary shares that Portage
may sell from time to time to Lincoln Park Capital Fund, LLC ("Lincoln") and an additional 94,508 shares that were issued
to Lincoln.

The Sales Agreement permits the Company to sell in an ATM offering up to $50,000,000 of ordinary shares from time to time, the amount of which is included in the $200,000,000 of securities that may be offered, issued and sold by the Company under the base prospectus. The sales under the prospectus will be deemed to be made pursuant to an "at the market" offering as defined in Rule 415(a)(4) promulgated under the Securities Act of 1933, as amended (the "Securities Act"). Upon termination of the Sales Agreement, any portion of the $50,000,000 included in the Sales Agreement prospectus that is not sold pursuant to the Sales Agreement will be available for sale in other offerings pursuant to the base prospectus. See Note 14, "Capital Stock," and Note 22, "Event After the Balance Sheet Date," for a further discussion.

During the quarter ended June 30, 2021, the Company commenced an "at the market" offering, under which it sold 90,888 ordinary shares generating gross proceeds of approximately $2.6 million ($2.5 million, net of commissions).

On June 24, 2021, the Company completed a firm commitment underwritten public offering of 1,150,000 ordinary shares at a public offering price of $23.00 per share for gross proceeds of approximately $26.5 million and was settled June 28, 2021. The Company incurred aggregate offering expenses for the public offering of approximately $1.8 million, including approximately $1.6 million of management, underwriting and selling expenses.

On July 6, 2022, the Company entered into a Purchase Agreement (the "Committed Purchase Agreement") with Lincoln, under which it may require Lincoln to purchase ordinary shares of the Company having an aggregate value of up to $30 million (the "Purchase Shares") over a period of 36 months. Pursuant to the Committed Purchase Agreement, Lincoln will be obligated to purchase the Purchase Shares in three different scenarios that are based on various market criteria and share amounts. The Company has the right to terminate the Committed Purchase Agreement for any reason, effective upon one business day prior written notice to Lincoln. Lincoln has no right to terminate the Committed Purchase Agreement. The requirement that Lincoln must make a purchase will be suspended based on various criteria such as there not being an effective registration statement for Lincoln to be able to resell the ordinary shares it is committed to purchase and market criteria such as the Company continuing to be Depository Trust Company eligible, among other things. The Committed Purchase Agreement does not impose any financial or business covenants on the Company, and there are no limitations on the use of proceeds. The Company may raise capital from other sources in its sole discretion; provided, however, that the Company shall not enter into any similar agreement for the issuance of variable priced equity-like securities until the three-year anniversary of the date of the Committed Purchase Agreement, excluding, however, an at-the-market transaction with a registered broker-dealer.

In October 2022, the Company restarted the ATM and commenced sales of ordinary shares pursuant to the Sales Agreement. Through December 31, 2022, the Company sold 88,072 ordinary shares under the ATM, generating net proceeds of approximately $0.6 million and sold 30,000 ordinary shares to Lincoln under the Committed Purchase Agreement for net proceeds totaling approximately $0.2 million.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

 

**NOTE 2. LIQUIDITY *(Cont'd)***

The Company has incurred substantial operating losses since inception and expects to continue to incur significant operating losses for the foreseeable future and may never become profitable. The losses result primarily from its conduct of research and development activities.

The Company historically has funded its operations principally from proceeds from issuances of equity and debt securities and would expect to enter the capital markets if additional funding is required.

***COVID-19 Effect***

Beginning in early March 2020, the COVID-19 pandemic and the measures imposed to contain this pandemic have disrupted and are expected to continue to impact the Company's business operations. The magnitude of the impact of the COVID-19 pandemic on the Company's productivity, results of operations and financial position, and its disruption to the Company's business and clinical programs and timelines, will depend, in part, on the length and severity of these restrictions and on the Company's ability to conduct business in the ordinary course. There was a slowdown and temporary lack of research and development resources, principally due to the focus of third party research on the pandemic. The research and development environment has substantially normalized in calendar 2022.

**NOTE 3. BASIS OF PRESENTATION**

***Statement of Compliance and Basis of Presentation***

These condensed consolidated interim financial statements have been prepared in accordance with the International Financial Reporting Standards ("IFRS") issued by the International Accounting Standards Board ("IASB"), IAS 34 *Interim Financial Reporting* and interpretations of the International Financial Reporting Interpretations Committee. These condensed consolidated interim financial statements do not include all of the information required for full annual financial statements and should be read in conjunction with the audited consolidated financial statements of the Company for the year ended March 31, 2022.

These condensed consolidated interim financial statements have been prepared on an historical cost basis except for items disclosed herein at fair value (see Note 19, "Financial Instruments and Risk Management"). In addition, these condensed consolidated interim financial statements have been prepared using the accrual basis of accounting, except for cash flow information.

The Company has only one reportable operating segment.

These condensed consolidated interim financial statements were approved and authorized for issuance by the Audit Committee and Board of Directors of the Company (the "Board") on March 1, 2023.

***Consolidation***

The condensed consolidated interim financial statements include the accounts of the Company and:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) SalvaRx, a wholly-owned subsidiary, incorporated on May 6, 2015 in the British Virgin Islands;

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 3. BASIS OF PRESENTATION *(Cont'd)***

***Consolidation (Cont'd)***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) iOx, a wholly-owned subsidiary incorporated in the U.K. on February 10, 2015. In September 2021, the Company, through SalvaRx, exchanged
certain notes, accrued interest, warrants and receivables in exchange for shares of iOx representing 60.49 % of the outstanding shares
of iOx. As a result of this exchange, the Company, through SalvaRx, increased its ownership of iOx from 60.49% to 78.32 %. On July 18,
2022, the Company purchased the remaining non-controlling interest of iOx. See Note 18, "Related
Party Transactions – Share Exchange Agreement – iOx," for a further discussion;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) Saugatuck, a 70 % owned subsidiary incorporated in the British Virgin Islands. Saugatuck and subsidiary refers to Saugatuck and Saugatuck
Rx LLC;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) PDS, a 100% owned subsidiary incorporated in Delaware, which provides human resources, and other services to each operating subsidiary
via a shared services agreement;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e) SalvaRx LLC, a wholly-owned subsidiary through SalvaRx;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(f) Saugatuck Rx LLC, a wholly-owned subsidiary of Saugatuck; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(g) Tarus Therapeutics, LLC ("Tarus"), a wholly-owned subsidiary of Portage.

All inter-company balances and transactions have been eliminated in consolidation.

Non-controlling interest in the equity of a subsidiary is accounted for and reported as a component of stockholders' equity. As of December 31, 2022, non-controlling interest represents the 30% shareholder ownership interest in Saugatuck and subsidiary, which is consolidated by the Company. See Note 11, "Unsecured Notes Payable – iOx Unsecured Notes Payable," for a discussion of the Company's settlement of loans with iOx and Note 18, "Related Party Transactions – Share Exchange Agreement – iOx" for a discussion of the Company's purchase of the balance of the non-controlling interest in iOx.

***Functional and Presentation Currency***

The Company's functional and presentation currency is the U.S. Dollar.

***Use of Estimates and Judgments***

The preparation of the condensed consolidated interim financial statements in conformity with IFRS requires management to make judgments, estimates and assumptions that affect the application of accounting policies and the reported amounts of assets, liabilities, income and expenses. Actual results may differ from these estimates.

Estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognized in the period in which the estimates are revised and in any future periods affected.

Significant areas where estimates are made include valuation of financial instruments (including the convertible note receivable), deferred tax assets, deferred tax liability, research and development costs, fair value used for acquisition of intangible assets, contingent consideration assumed and measurement of share-based compensation. Significant areas where critical judgments are applied include assessment of impairment of investments and goodwill and the determination of the accounting acquirer and acquiree in the business combination accounting.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 4. SIGNIFICANT ACCOUNTING POLICIES**

The accounting policies are set out in Note 4 to the fiscal 2022 audited consolidated financial statements of the Company. These policies have been applied consistently to all periods presented in these condensed consolidated interim financial statements.

**Recent Accounting Pronouncements**

***IFRS Pronouncements Issued***

**Impact of Adoption of Significant New IFRS Standards in 2022**

&nbsp;&nbsp;&nbsp;&nbsp;**(a)** **Annual Improvements to IFRS Standards 2018-2020** 

The annual improvements process addresses issues in the 2018-2020 reporting cycles including changes to IFRS 9, "Financial Instruments," IFRS 1, "First Time Adoption of IFRS," IFRS 16, "Leases," and IAS 41, "Biological Assets".

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;i) The amendment to IFRS 9 addresses which fees should be included in the 10% test for derecognition
of financial liabilities.

ii) The amendment to IFRS 1 allows a subsidiary adopting IFRS at a later date than its parent to also measure cumulative translation differences using the amounts reported by the parent based on the parent's date of transition to IFRS.

iii) The amendment to IFRS 16's illustrative example 13 removes the illustration of payments from the lessor related to leasehold improvements.

These amendments were effective for annual periods beginning on or after January 1, 2022. The adoption of these amendments did not have a material effect on the Company's annual consolidated financial statements or the condensed consolidated interim financial statements for the three and nine months ended December 31, 2022.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 4. SIGNIFICANT ACCOUNTING POLICIES *(Cont'd)***

&nbsp;&nbsp;&nbsp;&nbsp;**(b)** **IAS 37: Onerous Contracts – Cost of Fulfilling a Contract** 

The amendment to IAS 37 clarifies the meaning of costs to fulfil a contract and that before a separate provision for an onerous contract is established, an entity recognizes any impairment loss that has occurred on assets used in fulfilling the contract, rather than on assets dedicated to the contract. This amendment is effective for annual periods beginning January 1, 2022. The Company's adoption of IAS 37 did not have a material effect on its consolidated financial statements.

&nbsp;&nbsp;&nbsp;&nbsp;**(c)** **IAS 16: Proceeds Before Intended Use** 

The amendment to IAS 16 prohibits an entity from deducting from the cost of an item of property, plant and equipment any proceeds received from selling items produced while the entity is preparing the assets for its intended use (for example, the proceeds from selling samples produced when testing a machine to see if it is functioning properly). It also clarifies that an entity is testing whether the asset is functioning properly when it assesses the technical and physical performance of the asset. The amendment also requires certain related disclosures. This amendment is effective for annual periods beginning January 1, 2022. The Company's adoption of IAS 16 did not have a material effect on its consolidated financial statements.

**New Accounting Standards, Interpretations and Amendments**

Standards issued but not yet effective up to the date of issuance of the Company's condensed consolidated interim financial statements are listed below. This listing is of standards and interpretations issued, which the Company reasonably expects to be applicable at a future date. The Company intends to adopt those standards when they become effective.

&nbsp;&nbsp;&nbsp;&nbsp;**(a)** **IAS 1: Presentation of Financial Statements** 

The amendment to IAS 1 clarifies how to classify debt and other liabilities as either current or non-current. The amendment is effective for annual periods beginning on or after January 1, 2023. The Company is currently evaluating the new guidance and impacts on its consolidated financial statements.

&nbsp;&nbsp;&nbsp;&nbsp;**(b)** **Amendments to IFRS 10 and IAS 28: Sale or Contribution of Assets between an Investor and Its Associate or Joint Venture** 

The amendment addresses the conflict between IFRS 10, "Consolidated Financial Statements," and IAS 28, "Investments in Associates and Joint Ventures," in dealing with the loss of control of a subsidiary that is sold or contributed to an associate or joint venture. The amendments clarify that the gain or loss resulting from the sale or contribution of assets that constitute a business, as defined in IFRS 3, "Business Combinations," between an investor and its associate or joint venture, is recognized in full. Any gain or loss resulting from the sale or contribution of assets that do not constitute a business, however, is recognized only to the extent of unrelated investors' interests in the associate or joint venture. On September 11, 2014, the IASB issued narrow-scope amendments to IFRS 10 and IAS 28. The amendments were to be effective for annual periods commencing on or after January 1, 2016. In December 2015, the IASB decided to postpone the effective date of these amendments indefinitely.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 5. PREPAID EXPENSES AND OTHER RECEIVABLES**

---

| | | |
|:---|:---|:---|
| **** |  |  |
| (In thousands) | **As of<br> December 31, 2022** | **As of<br> March 31, 2022** |
| **Prepaid clinical research costs** | $**1286** | $– |
| **Prepaid insurance** | **164** | 1084 |
| **Research & development tax credits** | **169** | 169 |
| **Tax deposits** | **119** | 142 |
| **Other prepaid expenses** | **33** | 45 |
| **Other receivables** | **15** | 40 |
| &nbsp;&nbsp;&nbsp;**Total prepaid expenses and other receivables** | $**1786** | $1480 |

---

**NOTE 6. INVESTMENT IN ASSOCIATE**

Details of the Company's associate as of December 31, 2022 and March 31, 2022 are as follows:

---

| | | | | |
|:---|:---|:---|:---|:---|
| ****<br>**Name** | <br>**Principal Activity** | <br>**Place of Incorporation and <br>Principal Place of Business** | <br>**Voting Rights Held as <br>of December 31, 2022** | <br>**Voting Rights Held as <br>of March 31, 2022** |
| Associate: Stimunity S.A. | Biotechnology | Paris, France | 44.0% | 44.0% |

---

The following table is a roll-forward of the Company's investment in Stimunity S.A. ("Stimunity") as of and for the nine months ended December 31, 2022 and 2021:

---

| | | |
|:---|:---|:---|
| **** |  |  |
|  | **As of and for the<br> Nine Months Ended December 31,** | **As of and for the<br> Nine Months Ended December 31,** |
| (In thousands) | **2022** | **2021** |
| **Balance, beginning of period** | $**1673** | $1735 |
| **Share of (loss)** | **(268)** | (363) |
| **Balance, end of period** | $**1405** | $1372 |

---

On June 1, 2020, the Company made an additional investment of €0.9 million ($1.0 million) by executing its subscription for 2,479 Class A shares upon the achievement of certain milestones, as provided in the Shareholders' Agreement, increasing its equity share in Stimunity to 44%.

On July 13, 2022, the Company entered into a commitment with Stimunity to provide €600,000 under a convertible note (the "Stimunity Convertible Note") with a maturity date of September 1, 2023 (the "Maturity Date"). The Stimunity Convertible Note provides for simple interest at 7% per annum. The Stimunity Convertible Note is automatically converted into Series A shares upon Stimunity completing a Series A round for at least €20 million. If such subscription round is completed prior to the Maturity Date, the Company will be entitled to convert the Stimunity Convertible Note into Series A shares at the subscription share price less 15%. Additionally, if Stimunity completes a financing with a new category of shares (other than Common Shares or Series A shares) for at least €5 million (the "Minimum Raise"), the Company will have the right to convert the Stimunity Convertible Note and the historical Series A shares owned into the new category of shares. In the event that Stimunity does not close a financing prior to the Maturity Date or raises less than the Minimum Raise, the Company will have the right to convert the Stimunity Convertible Note into Series A shares at €363.00 per share or the raise price less 15%, whichever is lower. The Stimunity Convertible Note was funded on September 12, 2022. See Note 17, "Commitments and Contingent Liabilities – Stimunity Convertible Note," for a further discussion.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 6. INVESTMENT IN ASSOCIATE *(Cont'd)***

The Company accounts for its investment in Stimunity under the equity method and, accordingly, records its share of Stimunity's earnings or loss based on its ownership percentage. The Company recorded equity in loss in Stimunity of $152,000 and $261,000 for the three months ended December 31, 2022 and 2021, respectively, and $268,000 and $363,000 for the nine months ended December 31, 2022 and 2021, respectively.

Under the Shareholders' Agreement, Portage has (i) a preferential subscription right to maintain its equity interest in Stimunity in the event of a capital increase from the issuance of new securities by Stimunity, except for issuances of new securities for stock options under a merger plan or for an acquisition, and (ii) the right to vote against any (a) issuances of additional securities that would call for Portage to waive its preferential subscription right, or (b) any dilutive issuance.

**NOTE 7. INVESTMENT IN PRIVATE COMPANY**

The following is a discussion of the Company's investment in private company as of December 31, 2022 and March 31, 2022.

***Intensity Therapeutics, Inc.***

In connection with the SalvaRx Acquisition in fiscal 2019, the Company acquired a $4.5 million interest in Intensity, a private clinical stage biotechnology company, of 1.0 million shares, which represented a 7.5% equity interest in Intensity. The investment was recorded at fair value (which approximates cost) at the acquisition date. The investment in Intensity has been irrevocably designated as a financial asset recorded at fair value with gains and losses recorded through other comprehensive income ("OCI"). The fair value of the asset is determined by considering other comparable equity funding transactions by Intensity with unrelated investors.

On July 11, 2019, the Company entered into an agreement with Fast Forward Innovations Limited ("Fast Forward") to purchase Intensity Holdings Limited ("IHL"), a wholly-owned subsidiary of Fast Forward. The Company paid $1.3 million for IHL through the issuance of 129,806 ordinary shares. The sole asset of IHL consists of 288,458 shares of Intensity. This transaction increased the Company's ownership of Intensity to 1,288,458 shares.

There was no unrealized gain or loss recognized during the three and nine months ended December 31, 2021.

As of December 31, 2022 and March 31, 2022, the Company owned approximately 7.00% and approximately 7.35%, respectively, of the outstanding shares of Intensity, on a fully diluted basis.

On October 28, 2021, Intensity filed a Form S-1 Registration Statement with the SEC to register shares for an initial public offering, which was declared effective by the SEC, but subsequently withdrawn prior to closing. Intensity is still evaluating market conditions to determine the timing of an initial public offering. As of March 31, 2022, the Company had valued its investment in Intensity based on Intensity's Series C Preferred Stock Offering completed in 2020. If the initial public offering is successful, the Company will value its investment in Intensity based upon fair value (market price) and will record periodic changes in carrying value through OCI.

In October and November of 2022, Intensity filed amendments to its Form S-1 Registration Statement, which reflected a proposed offering price in the range of $4.00 - $5.00 per share, which is less than the Company's carrying value, which indicated impairment. Accordingly, the Company performed a fair value analysis and determined a fair value of $3.363 million, which was $4.046 million less than the then carrying value. The Company recognized an unrealized loss in value in Intensity of $4.046 million through OCI in the three and nine months ended December 31, 2022.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 8. ACQUISITION OF TARUS**

On July 1, 2022, the Company, its wholly-owned subsidiary, Tarus Acquisition Inc., and Tarus Therapeutics, Inc., a Delaware corporation advancing adenosine receptor agonists for the treatment of solid tumors, entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"). Under the structure of the Merger Agreement, Tarus Therapeutics, Inc. was ultimately merged into a wholly-owned subsidiary of the Company with the surviving entity renamed Tarus Therapeutics, LLC. The Tarus merger entitles the Company to the rights, know-how and/or ownership related to the assets developed by Tarus (the "Adenosine Compounds"), including:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. All rights and obligations related to the License Agreement between Tarus and Impetis Biosciences Limited, dated October 29, 2019,
and the Call Option under the License Agreement, which was exercised on November 5, 2020;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. All intellectual property and related documents owned or controlled by Tarus, including issued or pending patents, patent applications
and trade secrets. Additionally, any draft submissions and/or correspondence with patent authorities;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. All documents and supplies related to Adenosine Compounds including inventory, reagents, data, assays, reports, vendor agreements
and other information related to the preclinical development;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;4. All clinical supplies, manufacturing know-how, batch records, regulatory documents pertaining to the Adenosine
Compounds, certain reservations for manufacturing campaigns and any related agreements;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;5. All regulatory documents and correspondence pertaining to the Adenosine Compounds;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;6. All Contract Research Organization ("CRO") agreements and protocol related documents for Adenosine
Compounds;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;7. All current documents related to market research, forecasting, budgets and competitive intelligence; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;8. Rights to the use of Tarus Therapeutics' name for regulatory purposes.

As consideration for Tarus, the Company issued to Tarus shareholders an aggregate of 2,425,999 ordinary shares of Portage, calculated on the basis of $18 million divided by the 60-day Volume Weighted Average Price per share. The shares have not been registered with the SEC and are subject to lock-up agreements for terms ranging from six to twelve months. Additionally, milestone payments of up to $32 million in cash or Portage ordinary shares would be triggered upon achievement of future development and sales milestones. As a result of the transaction:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· The Company also assumed $2 million in short-term debt held by Tarus and deferred license milestones obligations
($1 million plus interest). The short-term debt was repaid by the Company in July 2022.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Upon enrolling the first patient in a Phase 2 clinical trial, the Company will pay an additional one-time
milestone payment of $15 million. Payment will be in the form of cash or Portage ordinary shares (at the discretion of the Company). The
remaining $17 million milestone is based on targeted commercial sales.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 8. ACQUISITION OF TARUS *(Cont'd)***

In connection with the acquisition of Tarus, the Company performed a fair value analysis of the assets acquired and liabilities assumed. The Company based the analysis on its clinical plan and timing of development events, and the probabilities of success determined primarily based upon empirical third party data and Company experience as well as the relevant cost of capital. In its fair value analysis, the Company used the Multi-Period Excess Earnings Method for PORT-6 and PORT-7 and the Replacement Cost Method for PORT-8 and PORT-9, determined based upon the maturity of the assets and the availability of sufficient data to measure fair value. The Company recorded the shares issued at $17.2 million, which represented the aggregate market value of the shares issued on July 1, 2022. The Company followed the guidance of IAS 3 and IAS 32 and recorded a deferred purchase price payable - Tarus of $8.538 million, which reflected the estimated acquisition date fair value of contractual milestone obligations incurred. The principal assumptions for determining the fair value include the timing of development events, the probabilities of success and the discount rate used. The Company recorded the obligation as a non-current liability, in accordance with the provisions IAS 32 with respect to the classification of financial assets and financial liabilities.

The Company will determine the fair value of the earnout shares at each balance sheet date. Any change to the fair value will be recorded in the Company's statements of operations and other comprehensive income (loss).

The following table summarizes the preliminary purchase price allocation to the fair value of assets acquired and liabilities assumed for Tarus:

---

| | |
|:---|:---|
| **Assets:** | (In thousands) |
| **Identifiable intangible assets** | $**28200** |
| **Goodwill** | **538** |
| **Total assets** | $**28738** |
| **Consideration:** |  |
| **Fair value of shares issued** | $**17200** |
| **Liabilities assumed** | **3000** |
| **Deferred purchase consideration at fair value** | **8538** |
| **Total liabilities** | $**28738** |

---

***Pro forma Information***

Summary unaudited pro forma condensed results of operations for the nine months ended December 31, 2022 and 2021, assuming the Tarus acquisition had occurred at the beginning of the earliest period presented, are as follows:

---

| | | |
|:---|:---|:---|
| **** |  |  |
|  | **For the Nine Months Ended December 31,** | **For the Nine Months Ended December 31,** |
| (In thousands) | **2022** | **2021** |
| **Loss from operations** | $**(12200)** | $(13431) |
| **Loss before provision for income taxes** | $**(12833)** | $(13110) |
| **Net loss** | $**(9927)** | $(12645) |
| **Total comprehensive loss for period** | $**(13945)** | $(12645) |
| **Loss per share** | $**(0.60)** | $(0.77) |

---

Summary unaudited pro forma condensed results of operations for the three months ended December 31, 2022 and 2021, assuming the Tarus acquisition had occurred at the beginning of the earliest period presented, are as follows:

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 8. ACQUISITION OF TARUS *(Cont'd)***

---

| | | |
|:---|:---|:---|
|  | **For the Three Months Ended December 31,** | **For the Three Months Ended December 31,** |
| (In thousands) | **2022 <sup>(1)</sup>** | **2021** |
| **Loss from operations** | $**(4759)** | $(4362) |
| **Loss before provision for income taxes** | $**(5302)** | $(4281) |
| **Net loss** | $**(7501)** | $(4398) |
| **Total comprehensive loss for year** | $**(11518)** | $(4398) |
| **Loss per share** | $**(0.44)** | $(0.23) |

---

**<sup>(1)</sup>** Includes the results of operations of Tarus for the period and, accordingly, there are no pro forma adjustments for the three months ended December 31, 2022.

These pro forma results are not necessarily indicative of what would have occurred if the acquisition had been in effect for the period presented, and they may not be indicative of results expected in the future.

**NOTE 9. GOODWILL**

The following is a roll-forward of goodwill:

---

| | | |
|:---|:---|:---|
| **** |  |  |
| (In thousands) | **As of**<br> **December 31, 2022** | **As of <br>March 31, 2022** |
| **Balance, beginning of period** | $**43324** | $43324 |
| **Tarus goodwill** | **538** | – |
| **Balance, end of period** | $**43862** | $43324 |

---

The Company's goodwill arose primarily from the acquisition of SalvaRx and its portfolio of several projects and investments.

As a result of the acquisition of Tarus in July 2022, the Company recorded $0.538 million of goodwill, representing the difference between the consideration paid of $28.738 million and the fair value of identifiable assets acquired of $28.2 million.

Under purchase accounting as of July 1, 2022 (the acquisition date), the assets and liabilities of Tarus Therapeutics, Inc., was recorded at their respective fair values and the excess of the acquisition consideration is goodwill. The purchase was in the form of a merger in which Tarus Therapeutics, Inc. was merged into Tarus Therapeutics, LLC., which is a wholly-owned subsidiary of Portage. All of the consideration for Tarus Therapeutics, LLC was paid or assumed by Portage and Portage will control the voting rights, the board of directors and the operations of Tarus Therapeutics, LLC.

As of December 31, 2022, the Company determined that it has only one cash-generating unit ("CGU"), the consolidated Portage Biotech Inc.

***Impairment Review***

On an annual basis, pursuant to IAS 36, "Impairment of Assets," the Company assesses its long-lived assets with definite lives, which are not yet available for use, for potential indicators of impairment.

If any such indication exists, the Company estimates the recoverable amount of the asset or CGU and compares it to the carrying value.

The Company performed its annual impairment test in each of fiscal 2022 and fiscal 2021 and estimated the recoverable amount of the above-noted CGU based on its value in use, which was determined using a capitalized cash flow methodology and categorized within level 3 of the fair market value hierarchy.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 9. GOODWILL *(Cont'd)***

The recoverable amount of the CGU has been determined based on its value in use. The recoverable amount considered assumptions based on probabilities of technical, regulatory and clinical acceptances and financial support. Further, management uses risk-adjusted cash flow projections based on financial budgets. Management believes that any reasonably possible change in the key assumptions on which the recoverable amount is based would not cause the carrying amount to exceed its recoverable amount. The discount rate has been determined based on the Company's best estimate of a risk adjusted discount rate.

The key assumptions used in the calculation of the recoverable amount include forecasts of the following:

&nbsp;&nbsp;&nbsp;&nbsp;(a) revenues;

&nbsp;&nbsp;&nbsp;&nbsp;(b) normalized operating expenses;

&nbsp;&nbsp;&nbsp;&nbsp;(c) income taxes; and

&nbsp;&nbsp;&nbsp;&nbsp;(d) capital expenditures.

Discounted cash flows are determined with reference to undiscounted risk adjusted cash flows, and the discount rate approximated 20.5% and 20.0% as of March 31, 2022 and 2021, respectively, based on the individual characteristics of the Company's CGU, the risk-free rate of return and other economic and operating factors.

As of December 31, 2022, management assessed whether any indications of impairment existed for the Company's CGU. As of December 31, 2022, the Company's market capitalization was less than its net assets, which is an external indicator of potential impairment. The Company evaluated this factor in conjunction with its assessment of the overall market environment and the progress made in developing the Company's assets. The Company determined that a test for impairment was not required and no impairment was recorded for the three and nine months ended December 31, 2022.

**NOTE 10. IN-PROCESS RESEARCH AND DEVELOPMENT AND DEFERRED TAX LIABILITY**

In-process research and development ("IPR&D") consists of the following projects (in thousands):

---

| | | | |
|:---|:---|:---|:---|
| ****<br>**Project #** | <br>**Description** | <br>**Value as of <br>December 31, 2022** | <br>**Value as of <br>March 31, 2022** |
| **iOx:** |  |  |  |
| PORT 2 (IMM60) | Melanoma & Lung Cancers | $**84213** | $84213 |
| PORT 3 (IMM65) | Ovarian/Prostate Cancers | **32997** | 32997 |
|  |  | **117210** | 117210 |
| **Oncomer/Saugatuck** | DNA Aptamers | **178** | 178 |
| **Tarus:** |  |  |  |
| PORT 6 & PORT 7 | Adenosine Receptors | **27138** |  |
| PORT 8 | Adenosine Receptors | **500** |  |
| PORT 9 | Adenosine Receptors | **562** | – |
|  |  | **28200** | – |
| **In-process research and development** |  | $**145588** | $117388 |
| **Deferred tax liability** |  | $**28409** | $30198 |

---

Additionally, at the end of each reporting period, the Company is required to assess whether there is any indication that an asset may be impaired. As indicated above, the Company identified an external indicator of potential impairment as of December 31, 2022. Pursuant to IAS 36, the Company completed its review of underlying fundamentals, execution, advancement of assets and value creation activities and concluded that no provision for impairment was required during the three and nine months ended December 31, 2022.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 10. IN-PROCESS RESEARCH AND DEVELOPMENT AND DEFERRED TAX LIABILITY *(Cont'd)***

Deferred tax liability represents iOx's estimated tax on the difference between book and tax basis of the IPR&D, which is taxable in the U.K, and the effect of usable net operating loss carryforwards.

As of December 31, 2022 and March 31, 2022, iOx had a net deferred tax liability of approximately $25.5 million and approximately $28.4 million, respectively. On January 8, 2019, the Company originally recognized a $19.8 million deferred tax liability for the difference between the book and income tax basis of IPR&D acquired as part of the SalvaRx Acquisition. As the iOx IPR&D is in the U.K., the deferred tax was recorded at 17%, the prevailing tax rate applicable in the U.K. at the time. In fiscal 2022, the Company recorded $7.0 million increase in deferred income taxes to reflect a future change in the U.K. income tax rate and recognized $0.7 million of current year losses and $0.8 million of prior year losses. The Company also recognized a $1.1 million decrease in deferred tax liability in fiscal 2022 to reflect the effect of the change in exchange rates on the liability settleable in British pound sterling. For the nine months ended December 31, 2022, the Company recognized the reduction in deferred tax liability of $1.8 million to reflect the effect of the change in exchange rates on the liability in the period and recognized $0.8 million of current period losses, as well as the tax rate change effect of $0.3 million on the current period losses.

**NOTE 11. UNSECURED NOTES PAYABLE**

The following is a roll-forward of current notes payable:

---

| | | |
|:---|:---|:---|
| (In thousands) | **iOx** | **Total** |
| Balance, April 1, 2021 | $150 | $150 |
| Exchange of notes payable and accrued interest for iOx shares | (150) | (150) |
| **Balance, March 31, 2022** | $**–** | $**–** |
| **Balance, December 31, 2022** | $**–** | $**–** |

---

***iOx Unsecured Notes Payable***

In connection with the SalvaRx Acquisition in January 2019, the Company assumed $2.0 million of 7% convertible notes issued by iOx, a wholly-owned subsidiary of SalvaRx (the "Convertible Notes"), of which the Company holds $1.9 million. As a result of the SalvaRx Acquisition, iOx became a subsidiary of the Company during the year ended March 31, 2019. In accordance with IFRS 3, the fair value, including interest receivable, of the Convertible Notes were effectively settled against the note receivable upon the business combination.

On September 8, 2021, the Company, through SalvaRx, completed a settlement of loans (including interest) to and receivables from iOx for services rendered in exchange for 23,772 ordinary shares of iOx at a price of £162. Simultaneously, the Company entered into an agreement with Oxford Sciences Innovation, Plc ("OSI"), the holder of $0.15 million notes plus accrued interest under which OSI exchanged the notes plus accrued interest for 820 shares of iOx. The Company followed the guidance provided by an IFRS Discussion Group Public Meeting dated November 29, 2016, following the general tenets of IAS 39, "Financial Instruments: Recognition and Measurement," and IFRIC 19, "Extinguishing Financial Liabilities with Equity Instruments," and recorded the exchange at historical cost. Additionally, no profit or loss was recorded in connection with the exchange. As a result of these transactions, the Company, through SalvaRx, increased its ownership of iOx from 60.49% to 78.32%. See Note 18, "Related Party Transactions – Share Exchange Agreement – iOx," for a further discussion.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 12. INCOME TAXES**

The Company is a BVI business company. The BVI government does not, under existing legislation, impose any income or corporate tax on corporations.

PDS is a U.S. corporation and is subject to U.S. federal, state and local income taxes, as applicable.

iOx is subject to U.K. taxes.

The (expense) benefit from income taxes consists of the following:

---

| | | |
|:---|:---|:---|
|  |  |  |
|  | **For the Nine Months Ended December 31,** | **For the Nine Months Ended December 31,** |
| (In thousands) | **2022** | **2021** |
| **Current:** |  |  |
| &nbsp;&nbsp;&nbsp;**Federal** | $**–** | $– |
| &nbsp;&nbsp;&nbsp;**State and local** | **(16)** |  |
| &nbsp;&nbsp;&nbsp;**Foreign** | **(8)** | 21 |
| **Total current** | **(24)** | 21 |
| **Deferred:** |  |  |
| &nbsp;&nbsp;&nbsp;**Federal** | **–** |  |
| &nbsp;&nbsp;&nbsp;**State and local** | **–** |  |
| &nbsp;&nbsp;&nbsp;**Foreign** | **2930** | 444 |
| **Total deferred** | **2930** | 444 |
| **Benefit from income taxes** | $**2906** | $465 |

---

The following is a reconciliation of the U.S. taxes to the effective income tax rates for the nine months ended December 31, 2022 and 2021 (U.S. Dollars in thousands):

---

| | | |
|:---|:---|:---|
| **** |  |  |
|  | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** |
|  | **2022** | **2021** |
| **Income (loss) on ordinary activities before tax** | $**(1230)** | $(1535) |
| **Statutory U.S. income tax rate** | **21.0%** | 21.0% |
| **Income tax benefit at statutory income tax rate** | **258** | 322 |
| **Losses recognized (unrecognized)** | **(282)** | (322) |
| **Income tax expense** | $**(24)** | $– |

---

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 12. INCOME TAXES *(Cont'd)***

At December 31, 2022, the Company had $0.9 million of federal net operating losses, which carryforward indefinitely but are limited to 80% of taxable income when utilized. As of December 31, 2022 and March 31, 2022, the Company had U.S. deferred tax assets of $0.2 million and $0.3 million, respectively.

The following is a reconciliation of the U.K. taxes to the effective income tax rates for the nine months ended December 31, 2022 and 2021 (U.S. Dollars in thousands):

---

| | | |
|:---|:---|:---|
|  | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** |
|  | **2022** | **2021** |
| **Loss on ordinary activities before tax** | $**4567** | $2434 |
| **Statutory U.K. income tax rate** | **19.0%** | 19.0% |
| **Loss at statutory income tax rate** | **868** | 462 |
| **Change (increase) in deferred income tax rate** | **274** |  |
| **Foreign currency effect** | **1788** | 444 |
| **Research and development credit** | **–** | 21 |
| **Losses (unrecognized)** | **–** | (462) |
| **Income tax benefit** | $**2930** | $465 |

---

Research and development credit receivables of $0.2 million and $0.2 million were included in prepaid expenses and other receivables on the condensed consolidated interim statements of financial position as of December 31, 2022 and March 31, 2022, respectively.

The following is a reconciliation of financial statement income (loss) to tax basis income (loss) (in thousands):

---

| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| **** |  |  |  |  |  |  |  |  |
|  | **Nine Months Ended December 31, 2022** | **Nine Months Ended December 31, 2022** | **Nine Months Ended December 31, 2022** | **Nine Months Ended December 31, 2022** | **Nine Months Ended December 31, 2021** | **Nine Months Ended December 31, 2021** | **Nine Months Ended December 31, 2021** | **Nine Months Ended December 31, 2021** |
|  | **United <br>States** | **BVI** | **United <br>Kingdom** | **Total** | **United <br>States** | **BVI** | **Foreign** | **Total** |
| **Pre-tax loss** | $**(1230)** | $**(7320)** | $**(4567)** | $**(13117)** | $(1535) | $(6802) | $(2434) | $(10771) |
| **Loss for which no benefit was taken** | **1622** | **–** | **–** | **1622** |  |  |  |  |
| **Losses not subject to tax** | **–** | **7320** | **–** | **7320** |  | 6802 |  | 6802 |
| **Utilization of losses not previously benefitted** | **(314)** | **–** | **–** | **(314)** | – | – | – | – |
| **Taxable income (loss)** | $**78** | $**–** | $**(4567)** | $**(4489)** | $(1535) | $– | $(2434) | $(3969) |

---

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 12. INCOME TAXES *(Cont'd)***

As of December 31, 2022 and March 31, 2022, the Company's deferred tax assets and liabilities in the U.K. consisted of the effects of temporary differences attributable to the following (in thousands):

---

| | | |
|:---|:---|:---|
|  | <br>**As of December 31,**<br>**2022** | <br>**As of March 31,**<br>**2022** |
| **Deferred tax assets:** |  |  |
| **Net operating loss** | $**(4394)** | $(3253) |
| **Deferred tax asset (unrecognized)** | **1500** | 1500 |
| **Deferred tax asset** | **(2894)** | (1753) |
| **Deferred tax liabilities:** |  |  |
| **In-process research and development** | **28409** | 30198 |
| **Deferred tax liability** | **28409** | 30198 |
| **Net deferred tax liability** | $**25515** | $28445 |

---

iOx generated research and development cash credits of approximately $0.02 million that have been recorded for the nine months ended December 31, 2021. There were no research and development cash credits recorded for the nine months ended December 31, 2022.

As of December 31, 2022 and March 31, 2022, iOx had a net deferred tax liability of approximately $25.5 million and approximately $28.4 million, respectively. On January 8, 2019, the Company originally recognized a $19.8 million deferred tax liability for the difference between the book and income tax basis of IPR&D acquired as part of the SalvaRx Acquisition. As the iOx IPR&D is in the U.K., the deferred tax was recorded at 17%, the prevailing tax rate applicable in the U.K. at the time. In fiscal 2022, the Company recorded $7.0 million increase in deferred income taxes to reflect a future change in the U.K. income tax rate and recognized $0.7 million of current year losses and $0.8 million of prior year losses. The Company also recognized a $1.1 million decrease in deferred tax liability in fiscal 2022 to reflect the effect of the change in exchange rates on the liability settleable in British pound sterling. For the nine months ended December 31, 2022, the Company recognized the reduction in deferred tax liability of $1.8 million to reflect the effect of the change in exchange rates on the liability in the period and recognized $0.8 million of current period losses, as well as the tax rate change effect of $0.3 million on the current period losses.

There is no expiration date for accumulated tax losses in the U.K. entities.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 13. WARRANT LIABILITY**

Below is the roll-forward of warrants issued by entity:

---

| | | | |
|:---|:---|:---|:---|
| **** |  |  |  |
|  | **PBI** | **PBI** | **PBI** |
|  | **Exercise Price** | **Warrants** | **Amount** |
|  | | | **In 000'$** |
| **Warrants outstanding, April 1, 2022** | $**6.64** | **33888** | $**33** |
| **Fair value adjustment as of December 31, 2022 (1)** | **–** | **(33888)** | **(33)** |
| **Warrants outstanding, December 31, 2022** | $**–** | **–** | $**–** |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) The Company recognized a gain of $0.001 million and $0.033 million in the three and nine months ended December 31, 2022, respectively,
to reflect the change in fair value of the underlying warrants. The Company recognized a gain of $0.342 million and $0.726 million in
the three and nine months ended December 31, 2021, respectively, to reflect the change in fair value of the underlying warrants. The warrants
expired in October 2022 unexercised.

**NOTE 14. CAPITAL STOCK**

&nbsp;&nbsp;&nbsp;&nbsp;(a) Authorized ordinary shares **:** Unlimited number of Portage ordinary shares without par value.

&nbsp;&nbsp;&nbsp;&nbsp;(b) The following is a roll-forward of Portage ordinary shares for the nine months ended December 31, 2022 and 2021:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **** |  |  |  |  |
|  | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** |
|  | **2022** | **2022** | **2021** | **2021** |
|  | **Ordinary<br> Shares** | **Amount** | **Ordinary <br> Shares** | **Amount** |
|  | **In 000'** | **In 000'$** | **In 000'** | **In 000'$** |
| **Balance, beginning of period** | **13349** | $**158324** | 12084 | $130649 |
| **Shares issued in Tarus acquisition** | **2426** | **17200** |  |  |
| **Shares issued in iOx exchange** | **1070** | **9737** |  |  |
| **Excess of non-controlling interest acquired over consideration – iOx** | **–** | **29609** |  |  |
| **Shares issued to Lincoln for commitment fee under Committed Purchase Agreement** | **94** | **900** |  |  |
| **Shares issued under public offering and ATM, net of issue costs** | **88** | **586** | 1241 | 27216 |
| **Purchase of shares issued under Committed Purchase Agreement, net of issue costs** | **30** | **184** |  |  |
| **Shares issued or accrued for services** | **13** | **90** | 4 | 90 |
| **Warrants exercised** | **–** | **–** | 16 | 339 |
| **Balance, end of period** | **17070** | $**216630** | 13345 | $158294 |

---

On June 16, 2020, the Company completed a private placement of 698,145 restricted ordinary shares at a price of $10.00 per share for gross proceeds of $6.98 million to accredited investors. Directors of the Company subscribed for 215,000 shares, or approximately 30.8% of the private placement, for proceeds of $2.15 million. The Company incurred costs of approximately $0.25 million in connection with the offering, which was treated as contra-equity on the Company's balance sheet.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 14. CAPITAL STOCK *(Cont'd)***

During the quarter ended June 30, 2021, the Company commenced an "at the market" offering, under which it sold 90,888 ordinary shares generating gross proceeds of approximately $2.6 million ($2.5 million, net of commissions).

On June 24, 2021, the Company completed a firm commitment underwritten public offering of 1,150,000 ordinary shares at a public offering price of $23.00 per share for gross proceeds of approximately $26.5 million and was settled June 28, 2021. The Company incurred aggregate offering expenses for the public offering of approximately $1.8 million, including approximately $1.6 million of management, underwriting and selling expenses.

The Company has issued 2,425,999 ordinary shares in connection with the acquisition of Tarus Therapeutics, Inc. and in connection with the Tarus Therapeutics, Inc.'s acquisition we may issue additional ordinary shares. See Note 8, "Acquisition of Tarus," for a further discussion.

On July 18, 2022, the Company completed the iOx Share Exchange Agreement under which it exchanged 1,070,000 ordinary shares for the remaining minority interest of 21.68% of iOx. See Note 18, "Related Party Transactions – Share Exchange Agreement – iOx," for a further discussion.

Additionally, on August 19, 2022, the Company issued 94,508 ordinary shares to Lincoln in consideration for entering into the $30 million Committed Purchase Agreement. See Note 17, "Commitments and Contingent Liabilities – Committed Purchase Agreement," for a further discussion.

In October 2022, the Company restarted the ATM and commenced sales of ordinary shares pursuant to the Sales Agreement. Through December 31, 2022, the Company sold 88,072 ordinary shares under the ATM, generating net proceeds of approximately $0.6 million and sold 30,000 ordinary shares to Lincoln under the Committed Purchase Agreement for net proceeds totaling approximately $0.2 million.

**NOTE 15. STOCK OPTION RESERVE**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) The following table provides the activity for the Company's stock option reserve for the nine months ended December 31, 2022
and 2021:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **** |  |  |  |  |
|  | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** |
|  | **2022** | **2022** | **2021** | **2021** |
| (In thousands) | **Non-Controlling Interest** | **Stock Option Reserve** | **Non-Controlling Interest** | **Stock Option Reserve** |
| **Balance, beginning of period** | $**11659** | $**16928** | $11468 | $7977 |
| **Share-based compensation expense** | **–** | **3614** | 191 | 6248 |
| **Settled in iOx exchange** | **(11659)** | **–** | – | – |
| **Balance, end of period** | $**–** | $**20542** | $11659 | $14225 |

---

***Stock Options***

On June 25, 2020, at the annual meeting of shareholders, the Company's new incentive stock option plan (the "2020 Stock Option Plan") was approved, which authorized the Company's directors to fix the option exercise price and to issue stock options under the plan as they see fit. The Company's 2020 Stock Option Plan is a 10% rolling stock option plan under which the Company's directors are authorized to grant up to a maximum of 10% of the issued and outstanding ordinary shares on the date of grant.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 15. STOCK OPTION RESERVE *(Cont'd)***

Effective January 13, 2021, the Company amended and restated its 2020 Stock Option Plan to permit the grant of additional types of equity compensation securities, including restricted stock units ("RSUs") and dividend equivalent rights (the "2021 Equity Incentive Plan"). The aggregate number of equity securities, which may be issued under the 2021 Equity Incentive Plan has not been changed. Pursuant to the 2021 Equity Incentive Plan, on January 13, 2021, the Company granted an aggregate of 868,000 stock options exercisable at a price of $17.75 per share, representing the closing price of the shares on the day immediately preceding the grant date, which expire on January 13, 2031 to various directors, officers and consultants of the Company. 350,000 options granted to members of the Board vest 1/3 on grant date, 1/3 on the first anniversary of the grant and 1/3 on the second anniversary of the grant. 518,000 options granted to consultants (one of whom is also a director of the Company) vest 1/3 on each of the first three anniversaries of the grant date.

Additionally, the Company granted 243,000 RSUs on January 13, 2021, with a fair value of $17.75 per share, which was the closing price on the day immediately preceding the grant date. The RSUs vested on the date of grant, but underlying shares cannot be sold until one of four of the following conditions are met: (1) a Change in Control (as defined in the Amended and Restated 2021 Equity Incentive Plan (defined below)), (2) the participant's Separation from Service (as defined in the Amended and Restated 2021 Equity Incentive Plan (defined below)), (3) the participant's death, or (4) the participant's Disability (as defined in the Amended and Restated 2021 Equity Incentive Plan (defined below)). In accordance with IFRS 2, "Share-based Payment," the Company recognized compensation expense of $4.3 million in the year ended March 31, 2021, in connection with the RSU grants.

***Amended and Restated 2021 Equity Incentive Plan and Grants of Stock Options and Restricted Stock Units***

On January 19, 2022, the Board unanimously approved the Amended and Restated 2021 Equity Incentive Plan (the "Amended and Restated 2021 Equity Incentive Plan"). The Amended and Restated 2021 Equity Incentive Plan provides for:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**(1)** An increase of aggregate number of shares available for awards to 2,001,812, which is equal to 15% of the issued and outstanding ordinary
shares of the Company as of January 19, 2022 subject to discretionary annual increases (on a cumulative basis) as may be approved by the
Board in future years by a number of shares not to exceed an additional 5% of the aggregate number of shares then outstanding;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**(2)** The authorization of incentive stock options (should shareholder approval be sought and obtained) under the Amended and Restated 2021
Equity Incentive Plan; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;**(3)** The provision of dividend equivalent rights to be issued when authorized.

Pursuant to the Amended and Restated 2021 Equity Incentive Plan, on January 19, 2022, the Company granted an aggregate of 302,000 stock options exercisable at a price of $10.22 per share, representing the average price of the shares on the grant date (January 19, 2022), which expire on January 19, 2032, to various directors, officers and consultants of the Company. A total of 13,800 of the 302,000 stock options were granted to two members of the Board and vest on the first anniversary of the grant date. The balance of 288,200 stock options was granted to employees (one of whom is also a director of the Company), and a consultant, and such stock options vest ratably on each of the first four annual anniversaries of the grant date.

Additionally, the Company granted 135,740 RSUs to employees (one of whom is also a director of the Company) on January 19, 2022, with a fair value of $10.22 per share, representing the average price of the shares on the grant date (January 19, 2022). The RSUs were fully vested and nonforfeitable as of the grant date and will expire on January 19, 2032.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 15. STOCK OPTION RESERVE *(Cont'd)***

On February 15, 2022, James Mellon, Linda Kozick and Mark Simon were appointed to the Board. Mr. Mellon owned approximately 23.9% of the Company's outstanding shares at that date. Additionally, Mr. Mellon had previously served as a member of the Board from 2016 to August 14, 2020. On February 15, 2022, in connection with the appointments, each of these directors were granted 13,800 non-qualified stock options, which vest ratably monthly over a three-year period. The options have an exercise price of $8.59 per share, the average price of the stock on February 15, 2022, the day immediately preceding the grant date, and will expire, if unexercised, on February 15, 2032.

On June 8, 2022, the Company granted 50,000 options to purchase shares to an executive of the Company. The options have an exercise price of $11.00, the average price of the stock on that date, vest ratably on each of the first four anniversaries of the grant date and will expire, if unexercised, on June 8, 2032.

The following is the weighted average assumptions used in connection with the June 8, 2022 option grant with respect to the Company's Amended and Restated 2021 Equity Incentive Plan:

---

| | |
|:---|:---|
| ****<br>**Assumption** | <br>**Unvested Options** |
| Risk free interest rate | 3.05% |
| Expected dividend | Nil |
| Expected volatility | 111% |
| Expected life | 6.25 years |
| Fair value of Portage option | $9.36 |

---

On July 27, 2022, the Company granted 15,900 options to purchase shares to a member of the Board. The options have an exercise price of $10.06, the average price of the stock on that date, vest ratably on each of the first four anniversaries of the grant date and will expire, if unexercised, on July 27, 2032.

The following is the weighted average assumptions used in connection with the July 27, 2022 option grant with respect to the Company's Amended and Restated 2021 Equity Incentive Plan:

---

| | |
|:---|:---|
| **Assumption** | **Unvested Options** |
| Risk free interest rate | 2.83% |
| Expected dividend | Nil |
| Expected volatility | 112% |
| Expected life | 5.75 years |
| Fair value of Portage option | $8.38 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The movements in the number of options issued for the nine months ended December 31, 2022 and 2021 were:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **** |  |  |  |  |
|  | **PBI Amended and Restated 2021 Equity Incentive Plan** | **PBI Amended and Restated 2021 Equity Incentive Plan** | **iOx Option Plan<br> (Subsidiary Plan)** | **iOx Option Plan<br> (Subsidiary Plan)** |
|  | **Nine Months Ended December 30,** | **Nine Months Ended December 30,** | **Nine Months Ended December 31,** | **Nine Months Ended December 31,** |
|  | **2022** | **2021** | **2022** | **2021** |
| **Balance, beginning of period** | **1151400** | 868000 | **1275** | 1924 |
| **Granted** | **65900** |  | **–** |  |
| **Expired or forfeited** | **–** | – | **(1275)** | (649) |
| **Balance, end of period** | **1217300** | 868000 | **–** | 1275 |
| **Exercisable, end of period** | **419705** | 116666 | **–** | 1275 |

---

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 15. STOCK OPTION RESERVE *(Cont'd)***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) The following is the weighted average exercise price and the remaining contractual life for outstanding options by plan as of December
31, 2022 and 2021:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **** |  |  |  |  |
|  | **PBI Amended and Restated <br>2021 Equity Incentive Plan** | **PBI Amended and Restated <br>2021 Equity Incentive Plan** | **iOx Option Plan<br> (Subsidiary Plan)** | **iOx Option Plan<br> (Subsidiary Plan)** |
|  | **As of December 31,** | **As of December 31,** | **As of December 31,** | **As of December 31,** |
|  | **2022** | **2021** | **2022** | **2021** |
| **Weighted average exercise price** | $**15.19** | 17.75 | $**–** | $162.14 |
| **Weighted average remaining contractual life (in years)** | **8.41** | 9.04 | **–** | 0.30 |

---

The vested options can be exercised at any time in accordance with the applicable option agreement. The exercise price was greater than the market price on the date of the grants for all options outstanding as of December 31, 2022 and March 31, 2022.

The Company recorded approximately $1.2 million and $3.6 million of share-based compensation expense with respect to the Amended and Restated 2021 Equity Incentive Plan in the three and nine months ended December 31, 2022, respectively. The Company recorded approximately $2.0 million and $6.2 million of share-based compensation expense with respect to the Amended and Restated 2021 Equity Incentive Plan in the three and nine months ended December 31, 2021, respectively. The Company expects to record additional share-based compensation expense of approximately $2.9 million through June 2026 with respect to the Amended and Restated 2021 Equity Incentive Plan. Additionally, there was no intrinsic value with respect to the stock options granted under the Amended and Restated 2021 Equity Incentive Plan at December 31, 2022 and was nil at December 31, 2021.

The Company recorded approximately $0.03 million and $0.2 million of share-based compensation expense related to the iOx stock option plan in the three and nine months ended December 31, 2021, respectively. As of December 31, 2021, the Company's iOx stock option plan was fully vested. Additionally, the intrinsic value of the iOx stock options was approximately $0.1 million at December 31, 2021, all of which was associated with vested exercisable options.

**NOTE 16. (LOSS) PER SHARE**

Basic earnings per share ("EPS") is calculated by dividing the net income (loss) attributable to ordinary equity holders of the Company by the weighted average number of ordinary shares outstanding during the period.

Diluted EPS is calculated by dividing the net income (loss) attributable to ordinary equity holders of the Company by the weighted average number of ordinary shares outstanding during the period plus the weighted average number of ordinary shares that would be issued on conversion of all the dilutive potential ordinary shares into ordinary shares.

The following table reflects the loss and share data used in the basic and diluted EPS calculations (U.S. Dollars in thousands, except per share amounts):

---

| | | | | |
|:---|:---|:---|:---|:---|
| **** |  |  |  |  |
|  | **Three Months Ended<br> December 31,** | **Three Months Ended<br> December 31,** | **Nine Months Ended<br> December 31,** | **Nine Months Ended<br> December 31,** |
|  | **2022** | 2021 | **2022** | 2021 |
| ***Numerator (in 000'$)*** |  |  |  |  |
| **Net loss attributable to owners of the Company** | $**(7485)** | $(3512) | $**(10163)** | $(9553) |
| ***Denominator (in 000')*** |  |  |  |  |
| **Weighted average number of shares – Basic and Diluted** | **17039** | 13344 | **15719** | 12966 |
| **Basic and diluted (loss) per share** | $**(0.44)** | $(0.26) | $**(0.65)** | $(0.74) |

---

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 16. (LOSS) PER SHARE *(Cont'd)***

The inclusion of the Company's stock options, RSUs and share purchase warrants in the computation of diluted loss per share would have an anti-dilutive effect on loss per share and are therefore excluded from the computation. Consequently, there is no difference between basic loss per share and diluted loss per share for the three and nine months ended December 31, 2022 and 2021. The following table reflects the outstanding securities by year that would have an anti-dilutive effect on loss per share and, accordingly, were excluded from the calculation.

---

| | | |
|:---|:---|:---|
|  | **As of December 31,** | **As of December 31,** |
|  | **2022** | **2021** |
| **Stock options** | **1217300** | 868000 |
| **Restricted stock units** | **378740** | 243000 |
| **Warrants** | **–** | 33888 |

---

Inclusion of outstanding options or other common stock equivalents in the computation of diluted loss per share would have an anti-dilutive effect on the loss per share and are therefore excluded from the computation. Consequently, there is no difference between loss per share and diluted loss per share.

**NOTE 17. COMMITMENTS AND CONTINGENT LIABILITIES**

Effective March 15, 2022, iOx entered into a Master Services Agreement (the "MSA") with Parexel International (IRE) Limited ("Parexel") under which Parexel agrees to provide services as CRO provided in a work order ("Work Order") effective June 1, 2022 under which Parexel will operate a Phase 2 trial of IMM60 and pembrolizumab in advanced melanoma and non-small lung cancer ("NSCLC"). The MSA provides for a five-year term, and the Work Order provides for a term to be ended upon the completion of the services required. The budget provides for service fees and pass-through expenses and clinical sites totaling $11.5 million. During the three months ended December 31, 2022, the Company executed two change orders resulting in a $0.6 million increase in the overall estimated budgeted costs.

***Stimunity Convertible Note***

On July 13, 2022, the Company entered into a commitment with Stimunity to provide €600,000 under the Stimunity Convertible Note. The Stimunity Convertible Note provides for simple interest at 7% per annum. The Convertible Note is automatically converted into Series A shares upon Stimunity completing a Series A round for at least €20 million. If such subscription round is completed prior to the Maturity Date, the Company will be entitled to convert the Stimunity Convertible Note into Series A shares at the subscription share price less 15%. Additionally, if Stimunity completes a financing with a new category of shares (other than Common Shares or Series A shares) for at least €5 million (the "Minimum Raise"), the Company will have the right to convert the Stimunity Convertible Note and the historical Series A shares owned into the new category of shares. In the event that Stimunity does not close a financing prior to the Maturity Date or raises less than the Minimum Raise, the Company will have the right to convert the Stimunity Convertible Note into Series A shares at €363.00 per share or the raise price less 15%, whichever is lower. The Stimunity Convertible Note was funded by the Company on September 12, 2022. In addition, the Company has eliminated 100% of the interest earned on the Stimunity Convertible Note in reporting its condensed consolidated financial results.

***Committed Purchase Agreement***

On July 6, 2022 (the "Signing Date"), the Company entered into the Committed Purchase Agreement with Lincoln, pursuant to which the Company may require Lincoln to purchase ordinary shares having an aggregate value of up to $30 million over a period of 36 months. Pursuant to the Committed Purchase Agreement, Lincoln will be obligated to purchase ordinary shares in three different scenarios that are based on various market criteria and share amounts.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 17. COMMITMENTS AND CONTINGENT LIABILITIES *(Cont'd)***

Upon execution of the Committed Purchase Agreement, the Company issued to Lincoln 94,508 ordinary shares, representing a 3% commitment fee valued at $0.9 million. The Company has the right to terminate the Committed Purchase Agreement for any reason, effective upon one business day prior written notice to Lincoln. Lincoln has no right to terminate the Committed Purchase Agreement. The Company is accounting for the commitment fee as a deferred commitment fee on the condensed consolidated interim statement of financial position as of December 31, 2022 and will amortize it pro-rata against equity sold under the Committed Purchase Agreement. Any unamortized balance will be written-off to operations at the expiration of the commitment.

The Committed Purchase Agreement does not impose any financial or business covenants on the Company and there are no limitations on the use of proceeds received by the Company from Lincoln. The Company may raise capital from other sources in its sole discretion; provided, however, that the Company shall not enter into any similar agreement for the issuance of variable priced equity-like securities until the three-year anniversary of the Signing Date, excluding, however, an at-the-market transaction with a registered broker-dealer.

In connection with the Committed Purchase Agreement, the Company and Lincoln entered into a Registration Rights Agreement, dated July 6, 2022 (the "Registration Rights Agreement"). Pursuant to the Registration Rights Agreement, the Company agreed, that it will file with the SEC the prospectus supplement to the Company's shelf registration statement pursuant to Rule 424(b) for the purpose of registering for resale the ordinary shares to be issued to Lincoln under the Committed Purchase Agreement. The prospectus supplement was filed on August 19, 2022.

The Company is obligated under the Tarus Merger Agreement and the iOx Share Exchange Agreement for certain third party earnouts based on the achievement of certain milestones. See Note 8, "Acquisition of Tarus," and Note 18, "Related Party Transactions – Share Exchange Agreement – iOx," for further discussions.

**NOTE 18. RELATED PARTY TRANSACTIONS**

***Investments***

The Company has entered into related party transactions and certain services agreements with its investees. Key management personnel of the Company have also entered into related party transactions with investees. Key management personnel are those persons having the authority and responsibility for planning, directing and controlling the activities of the Company. The Board, Chairman, Chief Executive Officer (the "CEO") and Chief Financial Officer are key management personnel.

The following subsidiaries and associates are considered related parties:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) **Stimunity**. The CEO of Portage is one of three members of the board of directors of Stimunity (see Note 6, "Investment
in Associate," and Note 17, "Commitments and Contingent Liabilities – Stimunity Convertible Note").

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) **iOx**. Upon the iOx Share Exchange on July 18, 2022, the non-Portage director resigned leaving two Portage insiders as directors.
The CEO of Portage is also the CEO of iOx, and the management team of Portage comprises the management team of iOx. See below for a discussion
of the Company's purchase of the non-controlling interest in iOx.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) **Saugatuck**. One of the three directorships on the board of directors of Saugatuck is controlled by Portage. Additionally, the
CEO of Portage is also the CEO of Saugatuck, and the management team of Portage comprises the management team of Saugatuck.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 18. RELATED PARTY TRANSACTIONS *(Cont'd)***

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) **Intensity**. The CEO of Portage is an officer of Intensity and from time to time, he provides consulting services to Intensity. The Company also sublets a portion of Intensity's office space.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e) **Portage Development Services Inc**. PDS is a 100% owned subsidiary incorporated in Delaware, which provides human resources and
other services to each operating subsidiary of Portage via a shared services agreement.

Transactions between the parent company and its subsidiaries, which are related parties, have been eliminated in consolidation and are not disclosed in this note.

On September 8, 2021, the Company, through SalvaRx, completed a settlement of loans (including interest) to and receivables from iOx for services rendered in exchange for 23,772 ordinary shares of iOx at a price of £162. Simultaneously, the Company entered into an agreement with OSI, the holder of $0.15 million notes plus accrued interest under which OSI exchanged the notes plus accrued interest for 820 shares of iOx. The Company followed the guidance provided by an IFRS Discussion Group Public Meeting dated November 29, 2016, following the general tenets of IAS 39, "Financial Instruments: Recognition and Measurement," and IFRIC 19, "Extinguishing Financial Liabilities with Equity Instruments," and recorded the exchange at historical cost. Additionally, no profit or loss was recorded in connection with the exchange. As a result of these transactions, the Company, through SalvaRx, increased its ownership of iOx from 60.49% to 78.32%.

***Share Exchange Agreement – iOx***

On July 18, 2022, the Company and SalvaRx entered into a Share Exchange Agreement (the "Share Exchange Agreement") with each of the minority shareholders of iOx (the "Sellers") resulting in the acquisition of the outstanding non-controlling ownership interest (approximately 22%) of iOx, which is developing the iNKT agonist platform. The Company followed IFRS 3, "Business Combinations," and IAS 27, "Separate Financial Statements," (which substantially replaced IAS 3) to account for this transaction. The Company achieved control of iOx, as defined, on January 8, 2019 upon the completion of the SalvaRx Acquisition. Further transactions whereby the parent entity acquires further equity interests from non-controlling interests, or disposes of equity interests but without losing control, are accounted for as equity transactions (i.e., transactions with owners in their capacity as owners). As such:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· the carrying amounts of the controlling and non-controlling interests are adjusted to reflect the changes in their relative interests
in the subsidiary;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· any difference between the amount by which the non-controlling interests is adjusted and the fair value of the consideration paid
or received is recognized directly in equity and attributed to the owners of the parent; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· there is no consequential adjustment to the carrying amount of goodwill, and no gain or loss is recognized in profit or loss.

The Company now owns the worldwide rights to its small molecule iNKT agonists, including lead programs PORT-2 and PORT-3. Under the terms of the Share Exchange Agreement, each Seller sold to the Company, and the Company acquired from each Seller, legal and beneficial ownership of the number of iOx shares held by each Seller, free and clear of any share encumbrances, in exchange for the issuance in an aggregate of 1,070,000 Portage ordinary shares to be allocated among the Sellers based upon their relative ownership. As a result of the Share Exchange Agreement, the Company owns 100% of the issued and outstanding shares of iOx.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 18. RELATED PARTY TRANSACTIONS *(Cont'd)***

As additional consideration for the sale of the iOx shares to the Company under the Share Exchange Agreement, the Sellers shall have the contingent right to receive additional shares ("Earnout Shares") from the Company having an aggregate value equal to $25 million calculated at the Per Share Earnout Price, as defined in the Share Exchange Agreement, upon the achievement of certain milestones defined as the dosing of the first patient in a Phase 3 clinical trial for either PORT-2 (IMM60 iNKT cell activator/agonist) or PORT-3 (PLGA-nanoparticle formulation of IMM60 combined with a NY-ESO-1 peptide vaccine). The Company shall have the option, in its sole and absolute discretion, to settle the Earnout Shares in cash. The Company followed IFRS 3 and IAS 32, "Financial Instruments: Presentation," to account for the fair value of the Earnout Shares. The principal assumptions for determining the fair value include the timing of development events, the probabilities of success and the discount rate used. The fundamental principle of IAS 32 is that a financial instrument should be classified as either a financial liability or an equity instrument according to the substance of the contract, not its legal form, and the definitions of financial liability and equity instrument. A financial instrument is an equity instrument if, and only if, both conditions (a) and (b) below are met:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) the instrument includes no contractual obligation to deliver cash or another financial asset to another entity,
and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) if the instrument will or may be settled in the issuer's own equity instruments, it is either:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) a non-derivative that includes no contractual obligation for the issuer to deliver a variable number of its
own equity instruments; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(ii) a derivative that will be settled only by the issuer exchanging a fixed amount of cash or another financial
asset for a fixed number of its own equity instruments.

When a derivative financial instrument gives one party a choice over how it is settled (for instance, the issuer or the holder can choose settlement net in cash or by exchanging shares for cash), it is a financial asset or a financial liability unless all of the settlement alternatives would result in it being an equity instrument. The financial instrument includes the exclusive right of the Company to settle the obligation with cash or equity and, accordingly, accounted for the fair value of the Earnout Shares as a non-current liability.

The Company recorded $5.478 million as the fair value estimate of the Earnout Shares, which is reflected as deferred obligation - iOx milestone on the condensed consolidated balance sheet included herein. The Company will determine the fair value of the Earnout Shares at each balance sheet date. Any change to the fair value will be recorded in the Company's statements of operations and other comprehensive income (loss). The Company recorded a (loss) from the change (increase) in fair value of the liability of $0.144 million and $0.090 million for the three and nine months ended December 31, 2022, respectively.

***Employment Agreements***

PDS entered into a Services Agreement with our CEO effective December 15, 2021 (the "CEO Services Agreement"). The CEO Services Agreement provides that the CEO will receive a base salary of $618,000, plus cost-of-living increases. The CEO Services Agreement provides for annual increases based upon the review of the base salary by the Board prior to the anniversary of the CEO Services Agreement provided that the annual increase cannot be less than the cost-of-living increase. The CEO Services Agreement also provides that the CEO is eligible to receive an annual performance-based bonus targeted at 59% of the applicable year's base salary, which bonus is earned based on the achievement of performance targets, as determined annually by the Board and communicated to the CEO in the first quarter of the year. Any annual bonus, to the extent earned, is to be paid no later than March 15 of the following year. The CEO Services Agreement is for an initial term of three years, after which it will automatically renew annually unless terminated in accordance with the CEO Services Agreement.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 18. RELATED PARTY TRANSACTIONS *(Cont'd)***

Under the CEO Services Agreement, the CEO may terminate his employment with PDS at any time for Good Reason (as defined in the CEO Services Agreement). PDS may terminate the CEO's employment immediately upon his death, upon a period of disability or without Just Cause (as defined in the CEO Services Agreement). In the event that the CEO's employment is terminated due to his death or Disability (as defined in the CEO Services Agreement), for Good Reason or without Just Cause, he will be entitled to accrued obligations (accrued unpaid portion of base salary, accrued unused vacation time and any unpaid expenses). Additionally, he may be entitled to Severance Benefits (as defined in the CEO Services Agreement), which include his then current base salary and the average of his annual bonus for the prior two completed performance years, paid over 12 monthly installments. Additionally, the CEO will be entitled to life insurance benefits and medical and dental benefits for a period of 12 months at the same rate the CEO and PDS shared such costs during his period of employment.

Additionally, all stock options (and any other unvested equity incentive award) held by the CEO relating to shares of the Company will be deemed fully vested and exercisable on the Termination Date (as defined in the CEO Services Agreement), and the exercise period for such stock options will be increased by a period of two years from the Termination Date.

If the CEO's employment by PDS is terminated by PDS or any successor entity without Just Cause (not including termination by virtue of the CEO's death or Disability) or by the CEO for Good Reason within 12 months following the effective date of a Change in Control (as defined in the CEO Services Agreement), then, in addition to paying or providing the CEO with the Accrued Obligations (as defined in the CEO Services Agreement), the Company will provide the following Change in Control Severance Benefits (as defined in the CEO Services Agreement):

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) PDS will pay the base salary continuation benefit for 18 months;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) PDS will pay the life insurance benefit for 18 months;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) PDS will pay an additional amount equivalent to the CEO's target annual bonus calculated using the bonus percentage for the
performance year in which the CEO's termination occurs. This bonus will be paid in 12 equal installments commencing on the first
payroll date that is more than 60 days following the date of termination of the CEO's employment, with the remaining installments
occurring on the first day of the month for the 11 months thereafter;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4) PDS will provide the CEO with continued medical and dental benefits, as described above, for 18 months; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5) All stock options (and any other unvested equity incentive award) held by the CEO relating to shares of the Company or its parent
will be deemed fully vested and exercisable on the Termination Date, as defined, and the exercise period for such stock options will be
increased by a period of two years from the Termination Date.

PDS entered into services agreements (individually, an "Executive Service Agreement," and collectively, the "Executive Service Agreements") with each of our five other senior officers (individually, "Executive" and collectively, "Executives"), three of which are dated as of December 1, 2021, one of which is dated December 15, 2021 and one of which is dated June 1, 2022. Each of the Executive Services Agreements provides for an initial term of two years that is automatically renewed for one-year periods (except two of the Executive Services Agreement, which provides for an initial term of one year and that is automatically renewed for one-year periods). The Executive Services Agreements initially provide for annual base salaries ranging from $175,000 to $348,000 (pro-rated for services rendered) and annual bonus targets ranging from 30% to 40%. They also provide for long-term incentives in the form of equity awards from time to time under the Portage Biotech Inc. Amended and Restated 2021 Equity Incentive Plan.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 18. RELATED PARTY TRANSACTIONS *(Cont'd)***

The Executive Services Agreements can be terminated by PDS without Just Cause, by death or Disability, or by the Executive (except one) for Good Reason (each as defined in the respective Executive Services Agreements). In such instances, the Executive Services Agreements provide for the payment of accrued obligations (accrued unpaid portion of base salary, accrued unused vacation time and any unpaid expenses). Additionally, the Executives (except two) are entitled to 50% of base salary plus 50% of average annual bonus earned over the prior two performance years, as well as prevailing life insurance benefits for a period of six months and medical and dental benefits for a period of six months at the prevailing rate PDS and the Executive were sharing such expenses.

Additionally, all stock options (and any other unvested equity incentive award) held by the Executives relating to shares of the Company will be deemed fully vested and exercisable on the Termination Date (as defined in the respective Executive Services Agreements), and the exercise period for such stock options will be increased by a period of two years from the Termination Date.

If an Executive's employment by PDS is terminated by the Company or any successor entity without Just Cause (not including termination by virtue of the Executive's death or Disability) or by the Executive (except one) for Good Reason within 12 months following the effective date of a Change in Control (as defined in the respective Executive Services Agreements), then, in addition to paying or providing the Executive with the Accrued Obligations (as defined in the respective Executive Services Agreements), the Company will provide the following Change in Control Severance Benefits (as defined in the respective Executive Services Agreements), except in two cases in which the Executive is entitled to Item (5) and 50% of Items (1) and (3) below:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) PDS will pay the Base Salary continuation benefit for 12 months;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) PDS will pay the life insurance benefit for 12 months;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) The Company will pay an additional amount equivalent to the Executive's target annual bonus calculated using the bonus percentage
for the performance year in which the Executive's termination occurs. This bonus will be payable in 12 equal installments commencing
on the first payroll date that is more than 60 days following the date of termination of the Executive's employment, with the remaining
installments occurring on the first day of the month for the 11 months thereafter;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4) PDS will provide the Executive with continued medical and dental benefits, as described above, for 12 months; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5) All stock options (and any other unvested equity incentive award) held by the Executive relating to shares of the Company or its parent
will be deemed fully vested and exercisable on the Termination Date and the exercise period for such stock options will be increased by
a period of two years from the Termination Date.

The Executive Services Agreements also include customary confidentiality, as well as provisions relating to assignment of inventions. The Executive Services Agreements also includes non-competition and non-solicitation of employees and customers provision that run during the Executive's employment with PDS and for a period of one year after termination of employment.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 18. RELATED PARTY TRANSACTIONS *(Cont'd)***

***Bonuses & Board Compensation Arrangements***

In December 2021, the Compensation Committee approved performance bonuses payable to senior management totaling $0.7 million. The bonuses were paid in December 2021.

In addition, the Compensation Committee of the Board established director compensation. Effective January 1, 2022, each non-executive Board member will be entitled to receive cash Board fees of $40,000 per annum, payable quarterly in arrears. Additionally, each non-executive Board member will be entitled to an annual grant of 6,900 options to purchase Portage ordinary shares, which would vest the first annual anniversary of the grant date. The Company incurred Board fees totaling $78,750 and $236,250 during the three and nine months ended December 31, 2022, respectively. There were no Board fees incurred during the three and nine months ended December 31, 2021.

Non-executive Board chairpersons will be entitled to an annual cash fee of $30,000, payable quarterly in arrears. In lieu of a non-executive chairperson, the lead director will be entitled to an annual cash fee of $20,000 per annum paid quarterly in arrears. Additionally, the chairperson of each of the Audit Committee, Compensation Committee and Nomination Committee will be entitled to annual fees of $15,000, $12,000 and $8,000, respectively, payable quarterly in arrears. Members of those committees will be entitled to annual fees of $7,500, $6,000 and $4,000, respectively, payable quarterly in arrears.

In December 2022, the Board approved executive performance bonuses, as recommended by the Compensation Committee, totaling $0.6 million, which is equivalent to 73.5% of original annual targets established by the Board in December 2021. The bonuses were approved based upon the original performance targets established. The Board further approved a payment structure of 25% of approved bonuses, which were paid in January 2023, with the balance of amounts due payable upon a new financing.

**NOTE 19. FINANCIAL INSTRUMENTS AND RISK MANAGEMENT**

The Company's financial instruments recognized in the Company's condensed consolidated interim statements of financial position consist of the following:

Fair value estimates are made at a specific point in time, based on relevant market information and information about financial instruments. These estimates are subject to and involve uncertainties and matters of significant judgment; and therefore, these estimates cannot be determined with precision. Changes in assumptions could significantly affect these estimates.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 19. FINANCIAL INSTRUMENTS AND RISK MANAGEMENT *(Cont'd)***

The following table summarizes the Company's financial instruments as of December 31, 2022 and March 31, 2022:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **** |  |  |  |  |
|  | **As of December 31, 2022** | **As of December 31, 2022** | **As of March 31, 2022** | **As of March 31, 2022** |
| (In thousands) | **Amortized Cost** | **Fair Value through Other Comprehensive <br>Income ("FVTOCI")** | **Amortized Cost** | **FVTOCI** |
| **<u>Financial assets</u>** |  |  |  |  |
| **Cash and cash equivalents** | $**13104** | $**–** | $23352 | $– |
| **Prepaid expenses and other receivables** | $**1786** | $**–** | $1480 | $– |
| **Convertible note receivable, including accrued interest** | $**–** | $**642** | $– | $– |
| **Investments** | $**–** | $**4768** | $– | $9082 |

---

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Amortized Cost** | **Fair Value through Profit or Loss ("FVTPL")** | **Amortized Cost** | **FVTPL** |
| **<u>Financial liabilities</u>** |  |  |  |  |
| **Accounts payable and accrued liabilities** | $**2422** | $**–** | $750 | $– |
| **Warrant liability** | $**–** | $**–** | $– | $33 |
| **Deferred purchase price payable - Tarus** | $**–** | $**8876** | $– | $– |
| **Deferred obligation - iOx milestone** | $**–** | $**5568** | $– | $– |

---

A summary of the Company's risk exposures as it relates to financial instruments are reflected below.

***Fair value of Financial Instruments***

The Company's financial assets and liabilities are comprised of cash and cash equivalents, receivables and investments in equities and private entities, accounts payable, warrant liability and unsecured notes payable.

The Company classifies the fair value of these transactions according to the following fair value hierarchy based on the amount of observable inputs used to value the instrument:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Level 1 – Values are based on unadjusted quoted prices available in active markets for identical assets or liabilities as of
the reporting date.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Level 2 – Values are based on inputs, including quoted forward prices for commodities, time value and volatility factors, which
can be substantially observed or corroborated in the marketplace. Prices in Level 2 are either directly or indirectly observable as of
the reporting date.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Level 3 – Values are based on prices or valuation techniques that are not based on observable market data. Investments are classified
as Level 3 financial instrument.

Assessment of the significance of a particular input to the fair value measurement requires judgment and may affect the placement within the fair value hierarchy.

Management has assessed that the fair values of cash and cash equivalents, other receivables and accounts payable approximate their carrying amounts largely due to the short-term maturities of these instruments.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 19. FINANCIAL INSTRUMENTS AND RISK MANAGEMENT *(Cont'd)***

The following methods and assumptions were used to estimate their fair values:

**Convertible Note Receivable:** The fair value of the Stimunity Convertible Note receivable denominated in euros at initial recognition is the transaction price for the instrument adjusted for the effect of the currency translation rate on the reporting date (Level 3) (see Note 17, "Commitments and Contingent Liabilities – Stimunity Convertible Note"). The Company recognized an unrealized gain through OCI on the change in fair value of the Stimunity Convertible Note receivable of $0.29 million for the three and nine months ended December 31, 2022.

**Investment in Intensity**: Fair value of the asset is determined by considering other comparable equity funding transactions by Intensity with unrelated investors (Level 3).

**Accrued Equity Issuable:** The fair value is estimated based on the average of the quoted market prices for the period in which the shares were earned (Level 1).

**Warrant Liability**: The fair value is estimated using a Black-Scholes model (Level 3) (see Note 13, "Warrant Liability").

**Deferred Purchase Price Payable - Tarus:** The fair value is the estimated value of a future contingent obligation based upon a fair value analysis performed in accordance with IFRS 3 at acquisition date, adjusted at each reporting date for any change in fair value (Level 3) (see Note 8, "Acquisition of Tarus"). The fair value was determined using the Income Approach and was based upon the analysis on the Tarus clinical plan, the timing of development events and the probabilities of success determined primarily based upon empirical third party data and Company experience, as well as the relevant cost of capital. The Company recorded a (loss) from the change (increase) in fair value of the liability of $0.354 million and $0.338 million for the three and nine months ended December 31, 2022, respectively.

**Deferred Obligation - iOx Milestone:** The fair value is the estimated value of a future contingent obligation based upon a fair value analysis performed in accordance with IFRS 3 as of July 18, 2022, the date of the Share Exchange Agreement, adjusted at each reporting date for any change in fair value (Level 3) (see Note 18, "Related Party Transactions – Share Exchange Agreement – iOx"). The fair value was determined using the Income Approach and based on factors including the clinical plan, the timing of development events and the probabilities of success determined primarily based upon empirical third party data and Company experience, as well as the relevant cost of capital. The Company recorded a (loss) from the change (increase) in fair value of the liability of $0.144 million and $0.090 million for the three and nine months ended December 31, 2022, respectively.

There have been no transfers between levels of the fair value hierarchy for the nine months ended December 31, 2022 and the year ended March 31, 2022.

The Company's financial instruments are exposed to certain financial risks: Credit Risk, Liquidity Risk and Foreign Currency Risk.

***Credit Risk***

Credit risk is the risk of loss associated with a counterparty's inability to fulfil its payment obligations. The credit risk is attributable to various financial instruments, as noted below. The credit risk is limited to the carrying value as reflected in the Company's condensed consolidated interim statements of financial position.

***Cash and cash equivalents*.** Cash and cash equivalents comprise cash on hand and on-demand deposits that are readily convertible to a known amount of cash with three months or less from date of acquisition and are subject to an insignificant risk of change in value. As of December 31, 2022 and March 31, 2022, cash equivalents was comprised of a money market account with maturities less than 90 days from the date of purchase. Cash and cash equivalents are held with major international financial institutions and therefore the risk of loss is minimal.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 19. FINANCIAL INSTRUMENTS AND RISK MANAGEMENT *(Cont'd)***

***Liquidity Risk***

Liquidity risk is the risk that the Company will encounter difficulty in satisfying financial obligations as they become due.

The Company's approach to managing liquidity is to ensure, as far as possible, that it will have sufficient liquidity to meet its liabilities when due, under both normal and stressed conditions without incurring unacceptable losses or risking harm to the Company's reputation. The Company holds sufficient cash and cash equivalents to satisfy obligations under accounts payable and accruals.

The Company monitors its liquidity position regularly to assess whether it has the funds necessary to meet its operating needs and needs for investing in new projects. The Company believes that it has sufficient funding to finance the committed drug development work, apart from meeting its operational needs for the foreseeable future.

However, as a biotech company at an early stage of development and without significant internally generated cash flows, there are inherent liquidity risks, including the possibility that additional financing may not be available to the Company, or that actual drug development expenditures may exceed those planned. The current uncertainty in global markets could have an impact on the Company's future ability to access capital on terms that are acceptable to the Company. There can be no assurance that required financing will be available to the Company. See Note 2, "Liquidity," and Note 14, "Capital Stock," for a discussion of the Company's share offering and Note 17, "Commitments and Contingent Liabilities – Committed Purchase Agreement," for a further discussion.

***Foreign Currency Risk***

While the Company operates in various jurisdictions, substantially all of the Company's transactions are denominated in the U.S. Dollar, except the deferred tax liability in the U.K. settleable in British pound sterling and the Stimunity Convertible Note receivable settleable in euros.

**NOTE 20. CAPITAL DISCLOSURES**

The Company considers the items included in shareholders' equity as capital. The Company had accounts payable and accrued expenses of approximately $2.4 million as of December 31, 2022 (approximately $0.8 million as of March 31, 2022) and current assets of approximately $15.5 million as of December 31, 2022 (approximately $24.8 million as of March 31, 2022). The Company's objectives when managing capital are to safeguard the Company's ability to continue as a going concern in order to pursue new business opportunities and to maintain a flexible capital structure, which optimizes the costs of capital at an acceptable risk.

The Company manages the capital structure and makes adjustments to it in light of changes in economic conditions and the risk characteristics of the underlying assets.

As of December 31, 2022, shareholders' equity attributable to the owners of the company was approximately $168.9 million (approximately $121.2 million as of March 31, 2022).

The Company is not subject to any externally imposed capital requirements and does not presently utilize any quantitative measures to monitor its capital. There have been no changes to the Company's approach to capital management during the nine months ended December 31, 2022 and 2021.

**Portage Biotech Inc.**

**Notes to Condensed Consolidated Interim Financial Statements**

**(U.S. Dollars)**

**(Unaudited – See Notice to Reader dated March 1, 2023)**

**NOTE 21. NON-CONTROLLING INTEREST**

---

| | | | |
|:---|:---|:---|:---|
| **** |  |  |  |
| (In thousands) | **iOx** | **Saugatuck <br>and subsidiary** | **Total** |
| **Non-controlling interest as of April 1, 2022** | $**44701** | $**(472)** | $**44229** |
| **Net income (loss) attributable to non-controlling interest** | **123** | **(171)** | **(48)** |
| **Purchase of non-controlling interest pursuant to Share Exchange Agreement** | **(44824)** | **–** | **(44824)** |
| **Non-controlling interest as of December 31, 2022** | $**–** | $**(643)** | $**(643)** |

---

---

| | | | |
|:---|:---|:---|:---|
| (In thousands) | **iOx** | **Saugatuck** | **Total** |
| **Non-controlling interest as of April 1, 2021** | $46173 | $(20) | $46153 |
| **Share-based compensation expense** | 191 |  | 191 |
| **Exchange of notes payable, accrued interest and warrants for iOx shares** | 184 |  | 184 |
| **Net (loss) attributable to non-controlling interest** | (436) | (317) | (753) |
| **Non-controlling interest as of December 31, 2021** | $46112 | $(337) | $45775 |

---

On September 8, 2021, the Company, through SalvaRx, completed a settlement of loans (including interest) to and receivables from iOx for services rendered in exchange for 23,772 ordinary shares of iOx at a price of £162. On July 18, 2022, the Company completed the acquisition of the remaining non-controlling interest in iOx, by issuing 1,070,000 shares of its ordinary shares and assuming certain milestone obligations. See Note 11, "Unsecured Notes Payable – iOx Unsecured Notes Payable," and Note 18, "Related Party Transactions – Share Exchange Agreement – iOx," for further discussions.

Saugatuck and subsidiary includes Saugatuck and its wholly-owned subsidiary, Saugatuck Rx LLC.

**NOTE 22. EVENT AFTER THE BALANCE SHEET DATE**

***Sale of Ordinary Shares***

In January and February 2023, the Company continued its share offering pursuant to the ATM and the Committed Purchase Agreement. From January 1, 2023 through February 24, 2023, the Company sold 63,279 ordinary shares under the ATM and generated net proceeds of approximately $0.3 million and sold 270,000 ordinary shares under the Committed Purchase Agreement for net proceeds totaling approximately $1.3 million.

## Exhibit 99.2

**Exhibit 99.2**

**PORTAGE BIOTECH INC.**

**THREE AND NINE MONTHS ENDED DECEMBER 31, 2022**

**MANAGEMENT'S DISCUSSION AND ANALYSIS**

Prepared as of March 1, 2023

Index

---

| | |
|:---|:---|
| Forward-Looking Statements | 3 |
| Nature of Operations and Overview | 4 |
| Summary of Results | 8 |
| Number of Ordinary Shares and Warrants | 8 |
| Business Environment – Risk Factors | 9 |
| Our Programs and Technology – Recent Developments | 9 |
| Results of Operations | 14 |
| Liquidity and Capital Resources | 19 |
| Key Contractual Obligations | 22 |
| Off-balance Sheet Arrangements | 23 |
| Transactions with Related Parties | 23 |
| Financial and Derivative Instruments | 23 |
| Use of Estimates and Judgments | 25 |
| New Accounting Standards, Interpretations and Amendments | 26 |
| Internal Controls over Financial Reporting | 26 |
| Public Securities Filings | 27 |

---

**Management Discussion and Analysis**

The following discussion and analysis by management of the financial condition and financial results for Portage Biotech Inc. for the three and nine months ended December 31, 2022, should be read in conjunction with the unaudited condensed consolidated interim financial statements for the three and nine months ended December 31, 2022, together with the related Management's Discussion and Analysis and audited consolidated financial statements for the year ended March 31, 2022, and Annual Report on Form 20-F for the year ended March 31, 2022.

#### Forward-Looking Statements
This document includes "forward-looking statements." All statements, other than statements of historical facts, included herein or incorporated by reference herein, including without limitation, statements regarding our business strategy, plans and objectives of management for future operations and those statements preceded by, followed by or that otherwise include the words "believe," "expects," "anticipates," "intends," "estimates" or similar expressions or variations on such expressions are forward-looking statements. We can give no assurances that such forward-looking statements will prove to be correct.

Each forward-looking statement reflects our current view of future events and is subject to risks, uncertainties and other factors that could cause actual results to differ materially from any results expressed or implied by our forward-looking statements.

Risks and uncertainties include, but are not limited to:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· our plans and ability to develop and commercialize product candidates and the timing of these development programs;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· clinical development of our product candidates, including the results of current and future clinical trials;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· the benefits and risks of our product candidates as compared to others;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· our maintenance and establishment of intellectual property rights in our product candidates;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· our need for financing and our estimates regarding our capital requirements and future revenues and profitability;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· our estimates of the size of the potential markets for our product candidates; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· our selection and licensing of product candidates.

These statements are based on assumptions and analyses made by us in light of our experience and our perception of historical trends, current conditions and expected future developments based on the focus of our business activities on biotechnology, as well as other factors we believe are appropriate in particular circumstances. However, whether actual results and developments will meet our expectations and predictions depends on a number of risks and uncertainties, which could cause actual results to differ materially from our expectations, including the risks set forth in "Item 3 - Key Information - Risk Factors" in the Company's Annual Report on Form 20-F for the year ended March 31, 2022.

Our business focus is that of being primarily a pharmaceutical development business subject to all of the risks of a pharmaceutical development business. We do not anticipate directly engaging in the post pharmaceutical development endeavors of manufacturing, marketing and distribution of the products we develop.

Consequently, all of the forward-looking statements made in this Management's Discussion and Analysis are qualified by these cautionary statements. We cannot assure you that the actual results or developments anticipated by us will be realized or, even if substantially realized, that they will have the expected effect on us or our business or operations.

Unless the context indicates otherwise the terms "Portage Biotech Inc.," "the Company," "our Company," "Portage," "we," "us" or "our" are used interchangeably in this Management's Discussion and Analysis and mean Portage Biotech Inc. and its subsidiaries. Capitalized terms used but not defined herein have the meaning ascribed to such terms in the Company's unaudited condensed consolidated interim financial statements for the three and nine months ended December 31, 2022.

**Nature of Operations and Overview**

Portage is a clinical stage immune-oncology company advancing treatments it believes will be first-in-class therapies that target known checkpoint resistance pathways to improve long-term treatment response and quality of life in patients with evasive cancers. Our access to next-generation technologies coupled with a deep understanding of biological mechanisms enables the identification of clinical therapies and product development strategies that accelerate these medicines through the translational pipeline. We currently are working on 14 immuno-oncology assets, of which ten are at various development stages, four of which are clinical stage. We source, nurture and develop the creation of early- to mid-stage treatments that we believe will be first-in-class therapies for a variety of cancers, by funding, implementing viable, cost effective product development strategies, clinical counsel/trial design, shared services, financial and project management to enable efficient, turnkey execution of commercially informed development plans. Our drug development pipeline portfolio encompasses products or technologies based on biology addressing known resistance pathways/mechanisms of current checkpoint inhibitors with established scientific rationales, including intratumoral delivery, nanoparticles, liposomes, aptamers, and virus-like particles.

**The Portage Approach**

Our mission is to advance and grow a portfolio of innovative, early-stage oncology assets based on the latest scientific breakthroughs focused on overcoming immune resistance and expanding the addressable patient population. Given these foundations, we manage capital allocation and risk as much as we oversee drug development. By focusing our efforts on translational medicine and pipeline diversification, we seek to mitigate overall exposure to many of the inherent risks of drug development.

Our approach is guided by the following core elements:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Portfolio diversification to mitigate risk and maximize optionality;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Capital allocation based on risk-adjusted potential, including staged funding to pre-specified scientific and clinical results;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Virtual infrastructure and key external relationships to maintain a lean operating base;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Internal development capabilities complemented by external business development;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Rigorous asset selection for broad targets with disciplined ongoing evaluation;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Focus on translational medicine and therapeutic candidates with single agent activity;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Conduct randomized trials early and test non-overlapping mechanisms of action; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Improve potential outcomes for patients with evasive cancers.

Our execution is achieved, in part, through our internal core team and our large network of experts, contract labs, and academic partners.

The Company believes that it is not subject to the regulation of the Investment Company Act of 1940, as amended ("40 Act"), based on the definition of investment companies. Notwithstanding the foregoing, as the Company primarily operates within the biomedical industry as a research and development ("R&D") business, the Company believes that it is also able to take advantage of the non-exclusive safe harbor of Rule 3a-8 promulgated under the 40 Act so as not to be characterized as an investment company. The Company has adopted a capital preservation policy referenced in that rule.

**Our Science Strategy**

Our goal is to develop immuno-oncology therapeutics that will dramatically improve the standard-of-care for patients with cancer. The key elements of our scientific strategy are to:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Build a pipeline of differentiated oncology therapeutic candidates that are diversified by mechanism, broad targets, therapeutic approach,
modality, stage of development, leading to a variety of deal types that can be executed with partners;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Expand our pipeline through research collaborations, business development, and internally designed programs;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Continue to advance and evolve our pipeline with a goal of advancing one therapeutic candidate into the clinic and one program into
Investigational New Drug ("IND")-enabling studies each year; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Evaluate strategic opportunities to accelerate development timelines and maximize the value of our portfolio.

**Our Pipeline**

We have built a pipeline of immuno-oncology therapeutic candidates and programs that are diversified by mechanism, therapeutic approach, modality, and stage of development. On an ongoing basis, we rigorously assess each of our programs using internally defined success criteria to justify continued investment and determine proper capital allocation. When certain programs do not meet our de-risking criteria for advancement, we look to monetize or terminate those programs and preserve our capital and resources to invest in programs with greater potential. As a result, our pipeline will continue to be dynamic.

The charts below set forth, as of February 1, 2023, the current state of our immuno-oncology therapeutic candidates and programs. The chart contains forward-looking information and projections based on management's current estimates. The chart information is based on and subject to many assumptions, as determined by management and not verified by any independent third party, which may change or may not occur as modeled. We undertake no obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. Before you make an investment decision regarding the Company, you should make your own analysis of forward-looking statements and our projections about candidate and program development and results.

![](pipe.jpg)

![](devprog.jpg)

**Our Business Model**

Portage is a development organization that is structured to facilitate flexibility in financing and ease of partnering, licensing, and merger/acquisition of individual assets and or technology platforms. The intellectual property ("IP") for each platform is held in separate private entities. Our employees and consultants work across the pipeline and we believe that this can (i) enhance operational efficiency, (ii) maintain an optimal cost structure, (iii) attract leading collaborators, and (iv) promote asset flexibility, as further described below.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· *Enhance operational efficiency*: We allocate resources while empowering managers to make program-level decisions in order to
increase productivity and speed. We believe this model enables a flexible organizational structure that can achieve scale through the
addition of programs without increasing burdensome bureaucracy or redundant infrastructure.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· *Maintain an optimal cost structure*: We have a relatively small number of employees and have partnered with a number of
 contract research organizations to leverage their infrastructure and expertise as needed instead of embarking on capital-intensive
 lab, manufacturing, and equipment expenditures. By reducing overhead costs, we believe we can increase the likelihood that we can
 generate a return on invested capital.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· *Attract leading collaborators and licensors*: Our pipeline is comprised of therapies we believe will be first-in-class
 therapies for a variety of cancers sourced via our extensive industry contacts and relationships (e.g., academia and pharmaceutical
 industry executives). On preclinical programs/technology, we initially established development structures enabling us to keep
 licensors economically incentivized at the program level. We believe that the experienced drug development leadership team and
 approach to resource allocation differentiate us from other potential licensees.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· *Leverage unique commoditized checkpoint marketplace and explore the potential to further enhance long-term clinical benefit for patients with cancer and also expand the eligible population to include those who do not currently receive anti-PD-1 therapy*: Presently there are multiple approved checkpoint therapeutics that lack differentiation, resulting in a competitive
 market dynamic, which will favor combination therapy. There is substantial opportunity for potential expansion in the PD-1 market
 with our invariant natural killer T-cell ("iNKT") agonists and adenosine inhibitors. Studies show that 70-80% of
 patients do not respond or have a limited response to existing monotherapies, such as PD-1 checkpoint inhibitors. We see potential
 for our unique approach of using iNKT agonists to initiate an immune response in tumors that have become refractory to checkpoint
 therapy or to increase the number of front-line patients achieving more durable responses. Combinations can improve this but often
 come at the cost of significant additional toxicity. The market is saturated with 14 approved PD-1 antibodies, and every major
 pharmaceutical company competes in this space. One illustrative example of potentially expanding eligible patients is with iNKT
 agonists upregulating expression of PD-L1. Patient populations that are typically not good candidates for PD-1 antibodies due to
 their lack or low expression of PD-L1 may be able to utilize iNKTs to sensitize tumors to PD-1 agents. Extending the use of PD-1
 antibodies represents a significant potential upside for one of these companies competing for market share, should they choose to
 partner with Portage.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· *Promote asset flexibility*: Our structure is designed to maximize flexibility and cost efficiency. This allows us to efficiently
pursue various subsidiary-level transactions, such as stock or asset sales, licensing transactions, strategic partnerships and/or co-development
arrangements. It also provides us with the flexibility to terminate programs with minimal costs if results do not meet our de-risking
criteria for advancement.

The Company is a BVI business company incorporated under the BVI Act with its registered office located at Clarence Thomas Building, P.O. Box 4649, Road Town, Tortola, BVI. Its USA agent, Portage Development Services Inc., is located at 61 Wilton Road, Westport, CT 06880.

The Company currently is a foreign private issuer under the United States Securities and Exchange Commission ("SEC") rules. It is also a reporting issuer under the securities legislation of the provinces of Ontario and British Columbia. Its ordinary shares were listed on the Canadian Securities Exchange ("CSE") under the symbol "PBT.U". On February 25, 2021, the ordinary shares of the Company began trading on the NASDAQ Capital Market ("NASDAQ") under the symbol "PRTG". As the principal market for the Company's ordinary shares is NASDAQ, the Company voluntarily delisted from the CSE on April 23, 2021.

#### Summary of Results
The following table summarizes financial information for the quarter ended December 31, 2022, and the preceding eight quarters (all amounts in 000'US$ except net loss per share, which are actual amounts). All share and per share amounts reflect the 1:100 reverse stock split effected June 5, 2020.

---

| | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| <br>**Quarter ended** | **Dec. 31,**<br>**2022** | **Sept. 30**<br>**2022** | **June 30,**<br>**2022** | **Mar. 31,**<br>**2022** | **Dec. 31,**<br>**2021** | **Sept. 30,**<br>**2021** | **June 30,**<br>**2021** | **Mar. 31,**<br>**2021** | **Dec. 31,**<br>**2020** |
| **Net (loss) attributable to owners of the Company** | **(7485)** | **(949)** | **(1729)** | **(7317)** | **(3512)** | **(2975)** | **(3066)** | **(11498)** | **(1184)** |
| **Working capital (1) to (8)** | **13110** | **15737** | **21138** | **24049** | **25639** | **27301** | **28106** | **1738** | **2875** |
| **Equity attributable to owners of the Company** | **168945** | **178434** | **120682** | **121205** | **125789** | **127140** | **127711** | **101449** | **104945** |
| **Net (loss) per share - Basic** | **(0.44)** | **(0.06)** | **(0.13)** | **(0.55)** | **(0.26)** | **(0.22)** | **(0.25)** | **(0.95)** | **(0.10)** |
| **Net (loss) per share - Diluted** | **(0.44)** | **(0.06)** | **(0.13)** | **(0.55)** | **(0.26)** | **(0.22)** | **(0.25)** | **(0.95)** | **(0.10)** |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) September 30, 2022 working capital is net of warrant liability of $8 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) June 30, 2022 working capital is net of warrant liability of $32 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) March 31, 2022 working capital is net of warrant liability of $33 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4) December 31, 2021 working capital is net of warrant liability of $159 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5) September 30, 2021 working capital is net of warrant liability of $535 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(6) June 30, 2021 working capital is net of warrant liability of $751 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(7) March 31, 2021 working capital is net of warrant liability of $1,120 settleable on a non-cash basis.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(8) December 31, 2020 working capital is net of warrant liability of $771 settleable on a non-cash basis.

**Number of Ordinary Shares and Warrants**

The following table summarizes the number of the Company's ordinary shares issued and outstanding and warrants at December 31, 2022 and March 1, 2023:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **As of,** | **December 31, 2022** | **December 31, 2022** | **March 1, 2023** | **March 1, 2023** |
| Shares issued and outstanding (a) (b) |  | 17065379 |  | 17403594 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) This amount excludes an aggregate 243,000 restricted stock units granted to the executive chairman and an employee on January 13,
2021, which vested immediately on the date of grant and are subject to certain restrictions and 135,740 restricted stock units granted
to employees (one of whom is also a director) on January 19, 2022 , which vested immediately
on the date of grant and are subject to certain restrictions.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The December 31, 2022 amount excluded 4,936 shares earned for services rendered from October 1, 2022 to December 31, 2022,
 accrued at December 31, 2022 for financial statement purposes and issued in January 2023. The March 1, 2023 amount excludes 4,127
 shares earned for services rendered in January and February 2023, accrued at February 28, 2023 but not yet issued.

**Business Environment – Risk Factors**

Please refer to the Annual Report on Form 20-F for the year ended March 31, 2022 for detailed information as the economic and industry factors that are substantially unchanged as of the date hereof.

**Our Programs and Technology – Recent Developments**

***Invariant Natural Killer T-cells (iNKT cells) Platform***

iNKT cells play an important role in anti-tumor immune responses and are a distinct class of T lymphocyte displaying a limited diversity of T-cell receptors. They recognize lipid antigens on the surface of tumor cells and produce large amounts of cytokines within hours of stimulation without the need for clonal expansion. Furthermore, iNKT cells activate multiple immune system components, including dendritic cells, T-cells and B-cells and stimulate an antigen-specific expansion of these cells. An operating subsidiary holds an exclusive license (with the right to sub-license) from the Ludwig Institute to use, research, develop and commercialize iNKT cell agonists, for the treatment of various forms of human disease, including cancer, under the Ludwig Institute's intellectual property and know-how.

***PORT-2 (IMM60)***

PORT-2 is an iNKT cell activator/agonist formulated in a liposome with a six-member carbon head structure that has been shown to activate both human and murine iNKT cells, resulting in dendritic cell ("DC") maturation and the priming of Ag-specific T and B cells.

In animal models, PORT-2 enhanced the frequency of tumor specific immune responses. iNKT cells are unique lymphocytes defined by their co-expression of surface markers associated with NK cells along with a T-cell antigen receptor. They recognize amphipathic ligands such as glycolipids or phospholipids presented in the context of the non-polymorphic, MHC class I-like molecule CD1d. Activated iNKT cells rapidly produce IFN-gamma and IL-4 and induce DC maturation and IL-12 production.

In August 2021, we dosed the first patient in the IMP-MEL PORT-2 clinical trial, a Phase 1/2 dose escalation and randomized expansion trial. The PORT-2 trial is expected to enroll up to 88 patients with melanoma or non-small cell lung carcinoma ("NSCLC") in order to evaluate safety and efficacy.

Preliminary Phase 1 data, presented at the Society for the Immunotherapy of Cancer ("SITC") Annual Meeting in November 2022, suggests PORT-2 was well tolerated when administered as a monotherapy, with no related severe or serious adverse events. All possibly related adverse events were mild to moderate and did not limit dosing. This has enabled a plan to accelerate opening of the combination safety cohort with pembrolizumab, in parallel with the ongoing high dose monotherapy cohort. Biomarker data presented at the SITC meeting in 2022 confirmed the mechanism of action (i.e., both activation of the innate and adaptive arms of the immune system). One of the two patients treated at the 3mg/m<sup>2</sup> dose had a mixed response with several tumors showing >50% reduction in diameter indicating single agent activity. We are encouraged by the growing patient data set that supports proof of concept for using an iNKT agonist in cancer treatment. PORT-2 has a favorable safety and tolerability profile as a monotherapy at all doses tested to date, has demonstrated evidence of single agent activity, and biomarkers confirm mechanistic potential of PORT-2 to activate both the adaptive and innate immune systems.

With the enhanced management team, efficient organization, and financial resources obtained in 2021, Portage has decided to expand the PORT-2 trial beyond the U.K. to accelerate clinical trials while addressing COVID-19 headwinds. The Company has hired a global clinical research organization, CRO-Parexel, and has submitted regulatory applications in other countries. By expanding the regions and sites contributing to the trial, Portage expects to accelerate enrollment in the planned Phase 2 portions of this trial. The Company entered into a clinical collaboration with Merck to supply pembrolizumab for this trial. Should there be delays in recruiting patients, it could result in increasing overall costs of program administration and ultimately, slow down the completion of the study and achievement of results.

In December 2022, the PORT-2 IND was accepted by the FDA and we anticipate the Phase 2 portion of the study to commence in the 2<sup>nd</sup> quarter of 2023. The Phase 2 portion of the study is an explanatory study.

***PORT-3 (IMM65)***

PORT-3 is a PLGA-nanoparticle formulation of IMM60 combined with a NY-ESO-1 peptide vaccine. Biodegradable PLGA-nanoparticles function as a delivery platform for immunomodulators and tumor antigens to induce a specific anti-tumor immune response. PLGA has minimal (systemic) toxicity and is used in various drug-carrying platforms as an encapsulating agent. Furthermore, co-formulating an iNKT inhibitor with a peptide vaccine in a particle has shown to be approximately five times more potent in killing cancer cells and generating an antigen-specific CD8 T-cell response than giving the two agents individually.

NY-ESO-1 is a cancer-testis antigen expressed during embryogenesis and in the testis, an immune privileged site. Furthermore, NY-ESO-1 expression is observed in several advanced cancers: Lung (2-32%), melanoma (40%), bladder (32-35%), prostate (38%), ovarian (30%), esophageal (24-33%), and gastric cancers (8-12%). Clinical trials have shown the safety and tolerability of Good Manufacturing Practices ("GMP")-grade NY-ESO-1 peptides in patients with cancer.

The first patient was dosed in 2021 and patients continue to enroll in the PRECIOUS Phase 1 trial of PORT-3 in patients with solid tumors. The Phase 1 portion of the trial is expected to enroll 15 patients. The trial was having difficulty identifying tumors that expressed NY-ESO-1, so it was amended to include all solid tumors regardless of expression to facilitate assessment of safety. This platform is designed to demonstrate proof of concept. The combination product has the ability to prime and boost an anti-tumor immune response. Our patent position extends to other known tumor antigens, and we are prepared to rapidly launch other assets into the clinic if we see strong activity of this formulation. Notably, Portage received additional grant support from the Horizon 2020 program to explore next generation targeted nanoparticles. Preliminary safety data for repeat dosing of PORT-3, a nanoparticle co-formulation of PORT-2 and NY-ESO-1 immunogenic peptides developed for the treatment of NY-ESO-1 positive solid tumors shows a favorable safety profile. We are evaluating opportunities and awaiting more data.

***Adenosine Receptor Antagonist Platform***

A critical mechanism of cancer immune evasion is the generation of high levels of immunosuppressive adenosine within the tumor microenvironment ("TME"). Research suggests that the TME has significantly elevated concentrations of extracellular adenosine. Engagement with adenosine receptors A2A and A2B triggers a dampening effect on the immune response, suppressing effector cell function and stabilizing immunosuppressive regulatory cells. Over-expression of the A2A and A2B receptors leads to poor prognosis in multiple cancers, including prostate cancer, colorectal cancer and lung adenocarcinoma, driven by a reduced ability to generate an immune response against the tumor.

These findings have made A2A and A2B high-priority targets for immunotherapeutic intervention. Portage is advancing the following four first-in-class adenosine inhibitors, which together represent a broad suite of adenosine-targeting approaches and will enable a comprehensive exploration of how targeting the adenosine pathway could potentially improve response in multiple cancer and non-cancer indications:

***PORT-6 (TT-10)***

Adenosine receptor type 2A ("A2A") inhibitor to treat A2A expressing solid tumors. We believe PORT-6 is more potent, more durable and more selective than other clinical stage A2A agents.

The Institutional Review Board has approved PORT-6, which should enable the Phase 1 study to commence by the end of Fiscal 2023 (March 2023).

***PORT-7 (TT-4)***

Adenosine receptor type 2B ("A2B") inhibitor to treat solid tumors; PORT-7 has a very selective profile that focuses on A2B. We expect to commence the study in late calendar 2023 or early calendar 2024.

***PORT-8 (TT-53)***

Dual inhibitor of adenosine receptors 2A and 2B (A2A/A2B) to treat solid tumors; Portage has the ability to combine these two to titrate the levels of A2A and A2B or has the ability to give the dual inhibitor (PORT-08). The PORT-8 program is a pre-clinical stage program.

***PORT-9 (TT-3)***

An A2B inhibitor to treat colorectal and gastrointestinal cancers.

In preparation for entering clinical trials for the adenosine programs, Portage will conduct an examination of which solid tumor types have a high expression of receptors A2A and A2B and enrich for patients that have high expression and therefore have potential to benefit most from treatment. Portage has designed the ADPORT-601 trial to evaluate the activity and safety of PORT-6 and PORT-7 alone and in combination. This trial will adapt over time and also include safety cohorts for these two agents with other immune activating agents including others from the Portage internal pipeline. Depending on the data, it can be expanded to evaluate either agent as monotherapy or a randomized comparison of either agent plus standard of care versus standard of care alone. The PORT-9 program is currently in the pre-clinical stage.

***Other Programs in Development***

 ****

***Amphiphilic platform***

DfuseRx SM, identifies combinations of anti cancer agents with amphiphilic diffuse enhancers that can passively enter into cancer cells. These novel formulations with unique IP can be directly injected into any solid tumors, and the payloads will diffuse across the membrane and disperse throughout the tumor, while sparing healthy cells. Once inside the cells, the technology is diluted away and the payloads are stuck inside the cells. The payloads are able to disperse to areas of the tumor that do not have blood supply and hence oral or IV drugs will not reach.

***PORT-1 (INT230-6)***

Intensity Therapeutics, Inc., our affiliate ("Intensity"), is developing INT230-6 (which we refer to as PORT-1) as a fixed dose formulation of cisplatin, vinblastine and a penetration enhancer. In animal models, the drug has shown efficacy in the majority of the animals, by a combination of direct killing of the cancer, and also a CD4 and CD8 T-cell response. Newly released interim safety and survival data from the Phase 1/2 IT-01 trial presented at ASCO 2021 demonstrated that both INT230-6 (PORT-1) monotherapy and combination therapy with immune checkpoint drugs are well-tolerated. The proven mechanism of action includes direct tumor-killing effects, as well as responses generated in non-injected tumors (abscopal responses) resulting from antigen presentation and immune activation. PORT-1 is the first of Portage's assets that entered the clinic and has demonstrated proof-of-concept in humans. The specific rapid local killing in the normal three-dimensional environment inside the body Portage believes is critical for robust antigen presentation and immune activation. Animal studies also showed synergy when combined with checkpoint inhibition. The product candidate has been dosed into 80 subjects in a Phase 1 and Phase 2 trial. This has shown proof of concept that the vast majority of the drug stays in the tumor, and a dose equivalent to three times the approved dose of the cytotoxic agent was very well tolerated without the typical chemo side effects. The most common adverse event related to the treatment was pain at the injection site. As a result, PORT-1 is being studied in nine Phase 2 trials including seven clinical collaborations with the two largest immuno-oncology drug manufacturers, BMS and Merck, in combination with their respective checkpoints in high unmet need medical types (pancreatic, gall bladder, sarcoma, non-microsatellite unstable colorectal, etc.). Intensity has also launched a randomized Phase 2 trial of INT230-6 vs. no treatment in early stage breast cancer (the "INVINCIBLE Trial") and has expanded its collaboration efforts with the INVINCIBLE Trial, conducted by the Ottawa Hospital and the Ontario Institute for Cancer Research. Intensity made three presentations on INT230-6 at the ASCO Annual Meeting in June 2022, with clinical data suggesting INT230-6 has potential to prolong survival when compared to historical results. An innovative window of opportunity trial in pre-surgical early stage breast cancer confirmed that one treatment with PORT-1, can result in near complete necrosis of breast tumors with an influx of key immune cells to process the dying tumor. In December 2022, Intensity presented INT230-6, which demonstrated the ability to cause up to 100% necrosis of presurgical breast cancer tumors in the window period from diagnosis to surgery and a Pathway enrichment analysis that demonstrated changes in T-cell activation, lymphocyte activation and inflammatory response from the INVINCIBLE Trial in a live Spotlight Session Poster Presentation at the San Antonio Breast Cancer Symposium, highlighting a new approach for the treatment of pre-surgical cancer patients.

As of December 31, 2022, the Company owned approximately 7.00% of Intensity's outstanding shares on a fully diluted basis.

***PORT-4, Nanolipogel ("NLG") co-formulation Platform***

Scientists are interested in novel ways to deliver multiple signals to the immune system in order to better activate an anti-tumor response. We have been impressed with a platform from Yale University that allows different types of agents to be packaged together and will concentrate them in tumors. We have licensed the platform for delivery of DNA aptamers and certain aptamer-small molecule-based combination products. In order to have multiple proprietary agents with known mechanisms of action, we have licensed rights to create DNA aptamers for immune-oncology targets and the first one developed is a proprietary PD1 aptamer, which has been placed in the NLG formulation. Early testing has shown the formulation properly modulates PD1 signaling in vitro similar to a PD1 antibody I. In non-clinical, in vivo experiments, the NLG-PD1 performed favorably compared to a mouse PD1 antibody. The current level of funding is expected to support exploration of multiple PD1 based co-formulations with small molecules and other DNA aptamers. The Company has conducted further research with the technology licensed from Yale University to co-deliver a PD1 blocking signal with a small molecule vascular endothelial growth factor inhibitor. We are looking to accelerate preclinical development of our PORT-4 platform, which may potentially increase the potency and improve the safety of numerous anti-cancer drugs through co-delivery of combination treatments to the tumor.

As of December 31, 2022, the Company owned approximately 70% of the outstanding shares of Saugatuck Therapeutics, Ltd., the subsidiary on which the PORT-4 Platform is managed.

***PORT-5, STING Agonist Platform***

Proprietary immune priming and boosting technology (using a STING agonist delivered in a virus-like particle) have shown proof of concept in animal models and Stimunity S.A. ("Stimunity") is beginning to progress the lead asset towards the clinic. This platform offers multiple ways to target immune stimulation towards the cancer, as well as to co-deliver multiple signals in a single product. Our researchers have developed a way to administer the product systemically and does not require direct tumor injections. The PORT-5 STING platform provides distinct advantages over chemical intratumoral approaches by offering a potent immune priming and boosting pathway within a virus-like particle ("VLP") to enable convenient systemic administration and traffic to the correct targets. This technology preferentially targets dendritic cells, which is differentiated from other chemical STING approaches. Stimunity is progressing this project towards clinical trials as well as developing next generation compounds. Given that this is a simple way to boost the immune response to any target, we are also pursuing a project to boost immune response to COVID and other pathogens. To that end, the team has received grant funding to study this technology with any COVID-19 vaccine to evaluate if it is possible to boost the immune response for immunocompromised or elderly patients. During April 2022, the American Association for Cancer Research showcased PORT-5 preclinical data at a late-breaking session that shows that one or more targeted immunotherapy agents could be packaged within a virus-like particle to increase potency, while enabling a selective immune activation. Given the progress to date, Stimunity is preparing the product to be able to file an IND.

As of December 31, 2022, the Company owned approximately 44% of the outstanding shares of Stimunity, the subsidiary on which the PORT-5 platform is managed.

***Early-Stage R&D Collaborations***

We continue to evaluate and test new antibody targets. Our interest here lies in the suppressive tumor micro-environment, and how we can down regulate or remove MDSC, TAMs, Tregs and other signals that impede the immune response from clearing cancer cells. One new effort that we have initiated is collaborations with two leading artificial intelligence/machine learning companies in order to screen for agents with specific attributes in this area. This may allow us a fast track an asset to the clinic with a re-purposed product.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Portage is collaborating with Dr. Robert Negrin and his team at Stanford University in an IST study to evaluate the use of PORT-2
with iNKT cell therapies in animals. This work will evaluate if an agonist co-administered with expanded or transformed iNKT cells can
further activate the transplanted and endogenous cells inside the patient. The Stanford collaboration will also study the impact iNKT
agonists have on driving an adaptive immune response and correcting the suppressive tumor microenvironment.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Portage entered into a Cooperative Research and Development Agreement ("CRADA") with the U.S. National Cancer Institute
("NCI"). Portage and NCI will advance preclinical and potential clinical development of STING agonists and anti-RAGE agents
for cancer vaccines. Portage and NCI will develop agents to enhance the efficacy of proprietary cancer vaccines and mouse model cancer
vaccines developed by NCI. After the Tarus acquisition, Portage amended the CRADA to include exploration of the different adenosine compounds.

**Three Months Ended December 31, 2022 Compared to the Three Months Ended December 31, 2021**

**(All Amounts in 000'$)**

#### Results of Operations
The following details major expenses for the three months ended December 31, 2022, compared to the three months ended December 31, 2021:

---

| | | |
|:---|:---|:---|
| **Three months ended December 31,** | **2022** | **2021** |
|  | In 000'$ | In 000'$ |
| **Operating expenses** | $**(4759)** | $(4169) |
| &nbsp;&nbsp;&nbsp;Change in fair value of deferred purchase price payable - Tarus and deferred obligation - iOx milestone | **(498)** |  |
| &nbsp;&nbsp;&nbsp;Share of loss in associate accounted for using equity method | **(152)** | (261) |
| &nbsp;&nbsp;&nbsp;Change in fair value of warrant liability | **8** | 342 |
| &nbsp;&nbsp;&nbsp;Foreign exchange transaction gain | **50** |  |
| &nbsp;&nbsp;&nbsp;Depreciation expense | **(1)** |  |
| &nbsp;&nbsp;&nbsp;Interest income (expense), net | **50** | (1) |
| **Loss before provision for income taxes** | **(5302)** | (4089) |
| &nbsp;&nbsp;&nbsp;Income tax expense | **(2199)** | (117) |
| **Net loss** | **(7501)** | (4206) |
| **Other comprehensive income (loss)** |  |  |
| &nbsp;&nbsp;&nbsp;Net unrealized loss on investments | **(4017)** | – |
| **Total comprehensive loss for period** | $**(11518)** | $(4206) |
| **Comprehensive loss attributable to:** |  |  |
| &nbsp;&nbsp;&nbsp;**Owners of the Company** | $**(11502)** | $(3512) |
| &nbsp;&nbsp;&nbsp;**Non-controlling interest** | **(16)** | (694) |
| **Total comprehensive loss for period** | $**(11518)** | $(4206) |

---

#### Results of Operations for the Three Months Ended December 31, 2022, Compared to the Three Months Ended December 31, 2021
The Company generated a net loss of approximately $7.5 million and other comprehensive loss of approximately $11.5 million during the three months ended December 31, 2022 (the "Fiscal 2023 Quarter"), compared to a net loss and other comprehensive loss of approximately $4.2 million during the three months ended December 31, 2021 (the "Fiscal 2022 Quarter"), an increase in net loss of $3.3 million and an increase in other comprehensive loss of $7.3 million, year-over-year.

The components of the change in net loss and other comprehensive loss are as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Operating expenses, which include R&D and general and administrative ("G&A") expenses, were $4.8 million in the
Fiscal 2023 Quarter, compared to $4.2 million in the Fiscal 2022 Quarter, an increase of $0.6 million, which is discussed more fully below.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· The Company's other items of income and expense were substantially non-cash in nature and aggregated approximately $0.54 million
net loss in the Fiscal 2023 Quarter, compared to approximately $0.08 million net income in the Fiscal 2022 Quarter, a change in other
items of income and expense of approximately $0.62 million, quarter-over-quarter. The primary reason for the quarter-over-quarter difference
in other items of income and expense was the difference in the fair value of warrants outstanding recognized in the quarter-over-quarter
period, which expired in October 2022, and a loss from the change (increase) in fair value of the deferred purchase price payable - Tarus
and deferred obligation - iOx milestone, partially offset by the change in the Company's share of an associate accounted for under
the equity method.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Additionally, the Company reflected a net deferred income tax expense of $2.2 million in the Fiscal 2023 Quarter, compared to a net
deferred income tax expense of $0.1 million in the Fiscal 2022 Quarter. The Fiscal 2023 Quarter includes the foreign currency effect on
deferred tax liability balance settleable in British pound sterling of $2.5 million partially offset by the recognition of current period
losses in the U.K. of $0.2 million and the related tax rate change effect of $0.1 million. The Fiscal 2022 Quarter reflected the foreign
currency effect on deferred tax liability balance settleable in British pound sterling at December 31, 2021, and the recoverable R&D
tax credits generated in the U.K.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· In the Fiscal 2023 Quarter, the Company performed a fair value analysis on its investment in Intensity, and determined a fair
 value of $3.363 million, which was $4.046 million less than the then carrying value. Accordingly, the Company recognized an
 unrealized loss in value in Intensity of $4.046 million through other comprehensive income ("OCI") in the Fiscal 2023
 Quarter, which was partially offset by an unrealized gain on the change in fair value of the Stimunity Convertible Note (as defined
 below) of $0.29 million.

***Operating Expenses***

The overall analysis of the operating expenses is as follows:

---

| | | |
|:---|:---|:---|
| **Three months ended December 31,** | **2022** | **2021** |
|  | In 000'$ | In 000'$ |
| &nbsp;&nbsp;&nbsp;Research and development | $**2535** | $1928 |
| &nbsp;&nbsp;&nbsp;General and administrative expenses | **2224** | 2241 |
| **Total operating expenses** | $**4759** | $4169 |

---

***Research and Development Costs***

R&D costs are comprised of the following:

---

| | | |
|:---|:---|:---|
| **Three months ended December 31,** | **2022** | 2021 |
|  | **In 000'$** | In 000'$ |
| &nbsp;&nbsp;&nbsp;Share-based compensation expense | $**627** | $1037 |
| &nbsp;&nbsp;&nbsp;Payroll-related expenses | **242** | 830 |
| &nbsp;&nbsp;&nbsp;Research and development – Clinical | **1392** |  |
| &nbsp;&nbsp;&nbsp;Research and development services and storage | **39** | 39 |
| &nbsp;&nbsp;&nbsp;Consulting fees | **93** | 22 |
| &nbsp;&nbsp;&nbsp;Research and development – CRADA | **31** |  |
| &nbsp;&nbsp;&nbsp;Other outside services – lab testing, peptide handling, etc. | **84** |  |
| &nbsp;&nbsp;&nbsp;Legal regarding Patents' registration | **27** | – |
| **Total research and development costs** | $**2535** | $1928 |

---

R&D costs increased by approximately $0.6 million, or approximately 32%, from approximately $1.9 million in the Fiscal 2022 Quarter, to approximately $2.5 million in the Fiscal 2023 Quarter. The increase was primarily attributable to clinical trial costs of $0.6 million associated with the iNKT clinical trial and the start-up and manufacturing costs associated with the adenosine assets (PORT-6 and PORT-7) acquired in the Tarus acquisition of $0.8 million. There were no such costs incurred in the Fiscal 2022 Quarter. The Fiscal 2023 Quarter also included $0.1 million in other R&D costs relating to outside services and an increase in compensation of $0.1 million for consultants involved in R&D activities. The Fiscal 2022 Quarter included $0.6 million for bonuses to employees and consultants, reflected in payroll-related expenses, which was approved and paid in the Fiscal 2022 Quarter. There was no such amount in the Fiscal 2023 Quarter. Additionally, the Fiscal 2022 Quarter included a higher amount of non-cash share-based compensation expense of $0.4 million, which was primarily attributable to (a) the continued vesting over time of grants; and (b) the decrease in the fair value of grants made after the Fiscal 2022 Quarter.

***General and Administrative Expenses***

Key components of G&A expenses are the following:

---

| | | |
|:---|:---|:---|
| **Three months ended December 31,** | **2022** | 2021 |
|  | **In 000'$** | In 000'$ |
| &nbsp;&nbsp;&nbsp;Professional fees | $**683** | $493 |
| &nbsp;&nbsp;&nbsp;Share-based compensation expense | **587** | 1076 |
| &nbsp;&nbsp;&nbsp;D&O insurance | **309** | 413 |
| &nbsp;&nbsp;&nbsp;Payroll-related expenses | **465** | 177 |
| &nbsp;&nbsp;&nbsp;Directors fees | **78** |  |
| &nbsp;&nbsp;&nbsp;Office and general expenses | **90** | 57 |
| &nbsp;&nbsp;&nbsp;Consulting fees | **12** | 25 |
| **Total general and administrative expenses** | $**2224** | $2241 |

---

G&A expenses were substantially the same in the year-over-year periods, as they decreased by approximately $0.02 million, or approximately 0.9%, from approximately $2.24 million in the Fiscal 2022 Quarter, to approximately $2.22 million in the Fiscal 2023 Quarter. Professional fees increased by $0.2 million due to legal fees and audit related fees associated with the updating of public filings and payroll-related expenses increased by $0.3 million due to the continued build-up of the Company's infrastructure. The Fiscal 2023 Quarter also included director's fees of $0.1 million (director's fees were approved and commenced January 2022). These increases were partially offset by a decrease in non-cash share-based compensation expense of $0.5 million attributable to the vesting of certain options granted in prior years and lower fair value associated with more recent grants and the decrease of $0.1 million associated with directors and officers ("D&O") insurance due to a decrease in the D&O premium market year-over-year.

**Nine Months Ended December 31, 2022 Compared to the Nine Months Ended December 31, 2021**

**(All Amounts in 000'$)**

#### Results of Operations
The following details major expenses for the nine months ended December 31, 2022, compared to the nine months ended December 31, 2021:

---

| | | |
|:---|:---|:---|
| **Nine months ended December 31,** | **2022** | **2021** |
|  | In 000'$ | In 000'$ |
| **Operating expenses** | $**(12499)** | $(11092) |
| &nbsp;&nbsp;&nbsp;Change in fair value of deferred purchase price payable - Tarus and deferred obligation - iOx milestone | **(428)** |  |
| &nbsp;&nbsp;&nbsp;Share of loss in associate accounted for using equity method | **(268)** | (363) |
| &nbsp;&nbsp;&nbsp;Change in fair value of warrant liability | **33** | 726 |
| &nbsp;&nbsp;&nbsp;Foreign exchange transaction loss | **(60)** |  |
| &nbsp;&nbsp;&nbsp;Depreciation expense | **(1)** |  |
| &nbsp;&nbsp;&nbsp;Interest income (expense), net | **106** | (42) |
| **Loss before provision for income taxes** | **(13117)** | (10771) |
| &nbsp;&nbsp;&nbsp;Income tax benefit | **2906** | 465 |
| **Net loss** | **(10211)** | (10306) |
| **Other comprehensive income (loss)** |  |  |
| &nbsp;&nbsp;&nbsp;Net unrealized loss on investments | **(4017)** | – |
| **Total comprehensive loss for period** | $**(14228)** | $(10306) |
| **Comprehensive loss attributable to:** |  |  |
| &nbsp;&nbsp;&nbsp;**Owners of the Company** | $**(14180)** | $(9553) |
| &nbsp;&nbsp;&nbsp;**Non-controlling interest** | **(48)** | (753) |
| **Total comprehensive loss for period** | $**(14228)** | $(10306) |

---

#### Results of Operations for the Nine Months Ended December 31, 2022, Compared to the Nine Months Ended December 31, 2021
The Company generated a net loss of approximately $10.2 million and other comprehensive loss of approximately $14.2 million during the nine months ended December 31, 2022 (the "Fiscal 2023 Nine Months"), compared to a net loss and other comprehensive loss of approximately $10.3 million during the nine months ended December 31, 2021 (the "Fiscal 2022 Nine Months"), a decrease in net loss of $0.1 million and an increase in other comprehensive loss of $3.9 million, year-over-year.

The components of the change in net loss and other comprehensive loss are as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Operating expenses, which include R&D and G&A expenses, were $12.5 million in the Fiscal 2023 Nine Months, compared to $11.1
million in the Fiscal 2022 Nine Months, an increase of $1.4 million, which is discussed more fully below.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· The Company's other items of income and expense were substantially non-cash in nature and aggregated approximately $0.6 million
net loss in the Fiscal 2023 Nine Months, compared to approximately $0.3 million net income in the Fiscal 2022 Nine Months, a change in
other items of income and expense of approximately $0.9 million, year-over-year. The primary reason for the year-over-year difference
in other items of income and expense was the reduction in the fair value of warrants recognized in the year-over-year period, which expired
in October 2022, and a loss from the change (increase) in fair value of the deferred purchase price payable - Tarus and deferred obligation
- iOx milestone, partially offset by a gain in interest income (expense), net.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Additionally, the Company reflected a net deferred income tax benefit of $2.9 million in the Fiscal 2023 Nine Months, compared to
a net deferred income tax benefit of $0.5 million in the Fiscal 2022 Nine Months. The Fiscal 2023 Nine Months includes the foreign currency
effect on deferred tax liability balance settleable in British pound sterling of $1.8 million and the recognition of current period losses
in the U.K. of $0.8 million, as well as the tax rate change effect of $0.3 million. The Fiscal 2022 Nine Months reflected recoverable
R&D tax credits generated in the U.K., partially offset by the foreign currency effect on deferred tax liability balance settleable
in British pound sterling at December 31, 2021.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· In the Fiscal 2023 Quarter, the Company performed a fair value analysis on its investment in Intensity, and determined a fair value
of $3.363 million, which was $4.046 million less than the then-carrying value. Accordingly, the Company recognized an unrealized loss
in value in Intensity of $4.046 million through OCI in the Fiscal 2023 Nine Months, which was partially offset by an unrealized gain on
the change in fair value of the Stimunity Convertible Note (as defined below) of $0.29 million.

***Operating Expenses***

The overall analysis of the operating expenses is as follows:

---

| | | |
|:---|:---|:---|
| **Nine months ended December 31,** | **2022** | **2021** |
|  | In 000'$ | In 000'$ |
| &nbsp;&nbsp;&nbsp;Research and development | $**5976** | $4804 |
| &nbsp;&nbsp;&nbsp;General and administrative expenses | **6523** | 6288 |
| **Total operating expenses** | $**12499** | $11092 |

---

***Research and Development Costs***

R&D costs are comprised of the following:

---

| | | |
|:---|:---|:---|
| **Nine months ended December 31,** | **2022** | 2021 |
|  | **In 000'$** | In 000'$ |
| &nbsp;&nbsp;&nbsp;Share-based compensation expense | $**1838** | $3195 |
| &nbsp;&nbsp;&nbsp;Payroll-related expenses | **1147** | 1271 |
| &nbsp;&nbsp;&nbsp;Research and development – Clinical | **2184** |  |
| &nbsp;&nbsp;&nbsp;Research and development services and storage | **282** | 145 |
| &nbsp;&nbsp;&nbsp;Consulting fees | **217** | 72 |
| &nbsp;&nbsp;&nbsp;Research and development – CRADA | **131** |  |
| &nbsp;&nbsp;&nbsp;Legal regarding Patents' registration | **67** | 115 |
| &nbsp;&nbsp;&nbsp;Other outside services – lab testing, peptide handling, etc. | **110** | 6 |
| **Total research and development costs** | $**5976** | $4804 |

---

R&D costs increased by approximately $1.2 million, or approximately 25%, from approximately $4.8 million in the Fiscal 2022 Nine Months, to approximately $6.0 million in the Fiscal 2023 Nine Months. The increase was primarily attributable to clinical trial costs of $1.3 million associated with the iNKT clinical trial and the start-up and manufacturing costs associated with the adenosine assets (PORT-6 and PORT-7) acquired in the Tarus acquisition of $0.9 million. There were no such costs incurred in the Fiscal 2022 Quarter. Additionally, the Company incurred costs of $0.1 million associated with the National Cancer Institute trial (CRADA program) in the Fiscal 2023 Nine Months. These increases were partially offset by a reduction in non-cash share-based compensation expense of $1.4 million with respect to options to purchase ordinary shares granted to employees, which was attributable to (a) the vesting over time of a portion of prior year grants; and (b) the decrease in the fair value of grants made in fiscal 2022.

***General and Administrative Expenses***

Key components of G&A expenses are the following:

---

| | | |
|:---|:---|:---|
| **Nine months ended December 31,** | **2022** | 2021 |
|  | **In 000'$** | In 000'$ |
| &nbsp;&nbsp;&nbsp;Professional fees | $**2353** | $1171 |
| &nbsp;&nbsp;&nbsp;Share-based compensation expense | **1776** | 3244 |
| &nbsp;&nbsp;&nbsp;D&O insurance | **928** | 1239 |
| &nbsp;&nbsp;&nbsp;Payroll-related expenses | **971** | 402 |
| &nbsp;&nbsp;&nbsp;Directors fees | **236** |  |
| &nbsp;&nbsp;&nbsp;Office and general expenses | **206** | 172 |
| &nbsp;&nbsp;&nbsp;Consulting fees | **53** | 60 |
| **Total general and administrative expenses** | $**6523** | $6288 |

---

G&A expenses increased by approximately $0.2 million, or approximately 3%, from approximately $6.3 million in the Fiscal 2022 Nine Months, to approximately $6.5 million in the Fiscal 2023 Nine Months. Professional fees increased by $1.2 million, of which approximately $0.7 million was attributable to legal fees associated with the Tarus acquisition and $0.2 million was attributable to stamp fees in the U.K. related to acquiring the outstanding minority interest of our iNKT agonist platform. There was also an increase in audit related expenses in the Fiscal 2023 Nine Months associated with the updating of public filings, as well as costs associated with the Tarus acquisition review. Additionally, payroll-related expenses increased by $0.6 million due to the formalization of a compensation program adopted in the Fiscal 2023 Nine Months designed to attract and retain management; along the same lines, the Company incurred $0.2 million director's fees in Fiscal 2023 Nine Months. There were no director's fees in the prior year period. These increases were partially offset by a decrease in non-cash share-based compensation expense of $1.5 million attributable to the vesting of certain options granted in prior years and lower fair value associated with more recent grants and the decrease of $0.3 million associated with D&O insurance, which was attributable to a decrease in the D&O premium market year-over-year.

#### Liquidity and Capital Resources
***Capital Resources***

Portage filed a shelf registration statement with the SEC under which it may sell ordinary shares, debt securities, warrants and units in one or more offerings from time to time, which became effective on March 8, 2021 ("Registration Statement"). In connection with the Registration Statement, Portage has filed with the SEC:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a base prospectus, which covers the offering, issuance and sale by Portage of up to $200,000,000 in the aggregate of the securities
identified above from time to time in one or more offerings;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a prospectus supplement covering the offer, issuance and sale by Portage in an "at the market" ("ATM") offering
of up to a maximum aggregate offering price of $50,000,000 of Portage's ordinary shares that may be issued and sold from time to
time under a Controlled Equity Offering Sales Agreement, dated February 24, 2021 (the "Sales Agreement"), with Cantor Fitzgerald
& Co., the sales agent ("Cantor Fitzgerald");

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a prospectus supplement dated June 24, 2021, for the offer, issuance and sale by Portage of 1,150,000 ordinary shares for gross proceeds
of approximately $26.5 million in a firm commitment underwriting with Cantor Fitzgerald; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· a prospectus supplement dated August 19, 2022, for the resale by Portage of up to $30,000,000 in ordinary shares that Portage may
sell from time to time to Lincoln Park Capital Fund, LLC ("Lincoln") and an additional 94,508 shares that were issued to Lincoln.

The Sales Agreement permits the Company to sell in an ATM offering up to $50,000,000 of ordinary shares from time to time, the amount of which is included in the $200,000,000 of securities that may be offered, issued and sold by the Company under the base prospectus. The sales under the prospectus will be deemed to be made pursuant to an ATM offering as defined in Rule 415(a)(4) promulgated under the Securities Act of 1933, as amended. Upon termination of the Sales Agreement, any portion of the $50,000,000 included in the Sales Agreement prospectus that is not sold pursuant to the Sales Agreement will be available for sale in other offerings pursuant to the base prospectus.

During the quarter ended June 30, 2021, the Company commenced an ATM offering, under which it sold 90,888 ordinary shares generating gross proceeds of approximately $2.6 million ($2.5 million, net of commissions).

On June 24, 2021, the Company completed the sale of 1,150,000 ordinary shares, including the underwriters' option, at a price of $23.00 per share, which generated gross proceeds of approximately $26.5 million and net proceeds of approximately $25.0 million, and was settled June 28, 2021.

On July 6, 2022, the Company entered into a Purchase Agreement (the "Committed Purchase Agreement") with Lincoln, under which it may require Lincoln to purchase ordinary shares of the Company having an aggregate value of up to $30 million (the "Purchase Shares") over a period of 36 months. Pursuant to the Committed Purchase Agreement, Lincoln will be obligated to purchase the Purchase Shares in three different scenarios that are based on various market criteria and share amounts. The Company has the right to terminate the Committed Purchase Agreement for any reason, effective upon one business day prior written notice to Lincoln. Lincoln has no right to terminate the Committed Purchase Agreement. The requirement that Lincoln must make a purchase will be suspended based on various criteria such as there not being an effective registration statement for Lincoln to be able to resell the ordinary shares it is committed to purchase and market criteria such as the Company continuing to be Depository Trust Company eligible, among other things. The Committed Purchase Agreement does not impose any financial or business covenants on the Company, and there are no limitations on the use of proceeds. The Company may raise capital from other sources in its sole discretion; provided, however, that the Company shall not enter into any similar agreement for the issuance of variable priced equity-like securities until the three-year anniversary of the date of the Committed Purchase Agreement, excluding, however, an ATM transaction with a registered broker-dealer.

Upon execution of the Committed Purchase Agreement, the Company issued to Lincoln 94,508 ordinary shares, representing a 3% commitment fee.

#### Liquidity
The accompanying condensed consolidated interim financial statements for the three and nine months ended December 31, 2022 have been prepared on a basis that assumes that the Company will continue as a going concern and that contemplates the continuity of operations, the realization of assets and the satisfaction of liabilities and commitments in the normal course of business. Accordingly, the accompanying condensed consolidated interim financial statements for the three and nine months ended December 31, 2022 do not include any adjustments relating to the recoverability and classification of recorded asset amounts or amounts of liabilities that might result from the outcome of this uncertainty.

As of December 31, 2022, the Company had cash and cash equivalents of approximately $13.1 million and total current liabilities of approximately $2.4 million. For the nine months ended December 31, 2022, the Company is reporting a net loss of approximately $10.2 million, and cash used in operating activities of approximately $7.4 million. As of January 31, 2023, the Company had approximately $13.2 million of cash and cash equivalents on hand. The Company believes its current cash resources are sufficient to fund operations for at least 13 months from March 1, 2023, the date of this Management's Discussion and Analysis.

During the quarter ended June 30, 2021, the Company made an ATM offering, under which it sold 90,888 ordinary shares generating gross proceeds of approximately $2.6 million ($2.5 million, net of commissions). On June 24, 2021, the Company completed a firm commitment underwritten public offering of 1,150,000 ordinary shares at a public offering price of $23.00 per share for gross proceeds of approximately $26.5 million and was settled June 28, 2021. The Company incurred aggregate offering expenses for the public offering of approximately $1.8 million, including approximately $1.6 million of management, underwriting and selling expenses.

In October 2022, the Company restarted the ATM and commenced sales of ordinary shares pursuant to the Sales Agreement. Through December 31, 2022, the Company sold 88,072 ordinary shares under the ATM, generating net proceeds of approximately $0.6 million and sold 30,000 ordinary shares to Lincoln under the Committed Purchase Agreement for net proceeds totaling approximately $0.2 million.

The Company has incurred substantial operating losses since inception and expects to continue to incur significant operating losses for the foreseeable future and may never become profitable. The losses result primarily from its conduct of R&D activities.

The Company historically has funded its operations principally from proceeds from issuances of equity and debt securities and would expect to enter the capital markets when additional funding is required.

***Cash Flows From Operating Activities***

During the Fiscal 2023 Nine Months, the Company used cash of $7.4 million to fund operating activities, compared to $4.5 million used during the Fiscal 2022 Nine Months. Operations in both the Fiscal 2023 Nine Months and the Fiscal 2022 Nine Months were funded by existing cash from the ATM offering and the public offerings in 2022 and 2021.

The Company's continuing operations are dependent upon any one of:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. the development and identification of economically recoverable therapeutic solutions;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. the ability of the Company to obtain the necessary financing to complete the research; or

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. the future profitable production, or proceeds, from the disposition of intellectual property.

The Company has incurred substantial operating losses since inception due to significant R&D spending and corporate overhead and expects to continue to incur significant operating losses for the foreseeable future and may never become profitable. As of December 31, 2022, the Company had cash and cash equivalents of approximately $13.1 million, working capital of approximately $13.1 million (including prepaid expenses of $1.8 million) and an accumulated deficit of approximately $65.2 million. The Company has funded its operations from proceeds from the sale of equity and debt securities. The Company will require significant additional capital to make the investments that it needs to execute its longer-term business plan. The Company's ability to successfully raise sufficient funds through the sale of debt or equity securities when needed is subject to many risks and uncertainties and, even if it were successful, future equity issuances would result in dilution to its existing stockholders and any future debt securities may contain covenants that limit the Company's operations or ability to enter into certain transactions.

#### Cash Flows From Investing Activities
During the Fiscal 2023 Nine Months, the Company used cash of $0.6 million to fund investing activities. During the Fiscal 2022 Nine Months, there were no investing cash flow activities.

On July 13, 2022, the Company entered into a commitment with Stimunity to provide €600,000 under a convertible note (the "Stimunity Convertible Note") with a maturity date of September 1, 2023. The Stimunity Convertible Note provides for interest at 7% per annum. The Stimunity Convertible Note was funded by the Company on September 12, 2022 by existing cash and cash provided under the Committed Purchase Agreement described above. See "Key Contractual Obligations" below for a further discussion.

***Cash Flows From Financing Activities***

During the Fiscal 2023 Nine Months, the Company used cash of $2.2 million to fund financing activities. During the Fiscal 2022 Nine Months, the Company generated net cash of $27.3 million from financing activities.

During the Fiscal 2023 Nine Months, as consideration for the Tarus acquisition, the Company issued to Tarus shareholders an aggregate of 2,425,999 ordinary shares of Portage, calculated on the basis of $18 million divided by the 60-day Volume Weighted Average Price per share. The shares have not been registered with the SEC and are subject to lock-up agreements for terms ranging from six to twelve months. Additionally, milestone payments of up to $32 million in cash or Portage ordinary shares would be triggered upon achievement of future development and sales milestones. As a result of the transaction:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· The Company also assumed $2 million in short-term debt held by Tarus and deferred license milestones obligations ($1 million plus
interest). The short-term debt was repaid by the Company in July 2022 and the repayment of the milestone obligation was paid by the Company
in August 2022; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Upon enrolling the first patient in a Phase 2 clinical trial, the Company will pay an additional one-time milestone payment of $15
million. Payment will be in the form of cash or Portage ordinary shares (at the discretion of the Company). The remaining $17 million
milestone is based on targeted commercial sales.

During the three months ended June 30, 2021, the Company commenced an ATM offering, under which it sold 90,888 ordinary shares generating gross proceeds of approximately $2.6 million ($2.5 million, net of commissions). On June 24, 2021, the Company completed a firm commitment underwritten public offering of 1,150,000 ordinary shares at a public offering price of $23.00 per share for gross proceeds of approximately $26.5 million and was settled on June 28, 2021. The Company incurred aggregate offering expenses for the public offering of approximately $1.8 million, including approximately $1.6 million of management, underwriting and selling expenses.

In October 2022, the Company restarted the ATM and commenced sales of ordinary shares pursuant to the Sales Agreement. Through December 31, 2022, the Company sold 88,072 ordinary shares under the ATM, generating net proceeds of approximately $0.6 million and sold 30,000 ordinary shares to Lincoln under the Committed Purchase Agreement for net proceeds totaling approximately $0.2 million.

#### Key Contractual Obligations
Details of contractual obligations, commitments and contingent liabilities are provided in Note 17, "Commitments and Contingent Liabilities," to the unaudited condensed consolidated interim financial statements for the three and nine months ended December 31, 2022.

On July 1, 2022, the Company, its wholly-owned subsidiary, Tarus Acquisition Inc., and Tarus Therapeutics, Inc., a Delaware corporation advancing adenosine receptor agonists for the treatment of solid tumors, entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"). Under the structure of the Merger Agreement, Tarus Therapeutics, Inc. was ultimately merged into a wholly-owned subsidiary of the Company with the surviving entity renamed Tarus Therapeutics, LLC ("Tarus").

As consideration for Tarus, the Company issued to Tarus shareholders an aggregate of 2,425,999 ordinary shares of Portage, calculated on the basis of $18 million divided by the 60-day Volume Weighted Average Price per share. The shares have not been registered with the SEC and are subject to lock-up agreements for terms ranging from six to twelve months. Additionally, payments of up to $32 million in cash or Portage ordinary shares would be triggered upon achievement of future development and sales milestones. As a result of the transaction:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· The Company also assumed $2 million in short-term debt held by Tarus and deferred license milestones obligations ($1 million plus
interest), for an aggregate of $3 million in liabilities. The Company repaid the short-term debt in July 2022.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Upon enrolling the first patient in a Phase 2 clinical trial, the Company will pay an additional one-time
payment of $15 million. Payment will be in the form of cash or Portage ordinary shares (at the discretion of the Company). The remaining
$17 million milestone is based on target commercial sales.

On July 13, 2022, the Company entered into a commitment with Stimunity to provide €600,000 under the Stimunity Convertible Note with a maturity date of September 1, 2023 (the "Maturity Date"). The Stimunity Convertible Note provides for interest at 7% per annum. The Stimunity Convertible Note is automatically converted into Series A shares upon Stimunity completing a Series A round for at least €20 million. If such subscription round is completed prior to the Maturity Date, the Company will be entitled to convert the Stimunity Convertible Note into Series A shares at the subscription share price less 15%. Additionally, if Stimunity completes a financing with a new category of shares (other than Common Shares or Series A shares) for at least €5 million (the "Minimum Raise"), the Company will have the right to convert the Stimunity Convertible Note and the historical Series A shares owned into the new category of shares. In the event that Stimunity does not close a financing prior to the Maturity Date or raises less than the Minimum Raise, the Company will have the right to convert the Stimunity Convertible Note into Series A shares at €363.00 per share or the raise price less 15%, whichever is lower. The Stimunity Convertible Note was funded by the Company on September 12, 2022 by existing cash and cash provided under the Committed Purchase Agreement described above.

On July 18, 2022, the Company and its wholly-owned subsidiary, SalvaRx Ltd. ("SalvaRx"), entered into a Share Exchange Agreement (the "Share Exchange Agreement") with each of the minority shareholders of iOx (the "Sellers") resulting in the acquisition of the outstanding non-controlling ownership interest (approximately 22%) of iOx, which is developing the iNKT agonist platform. The Company followed International Financial Reporting Standards ("IFRS") 3, "Business Combinations," and IAS 27, "Separate Financial Statements," (which substantially replaced IAS 3) to account for this transaction. The Company achieved control of iOx, as defined, on January 8, 2019 upon the completion of Portage's acquisition of SalvaRx. Further transactions whereby the parent entity acquires further equity interests from non-controlling interests, or disposes of equity interests but without losing control, are accounted for as equity transactions (i.e., transactions with owners in their capacity as owners). As such:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· the carrying amounts of the controlling and non-controlling interests are adjusted to reflect the changes in their relative interests
in the subsidiary;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· any difference between the amount by which the non-controlling interests is adjusted and the fair value of the consideration paid
or received is recognized directly in equity and attributed to the owners of the parent; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· there is no consequential adjustment to the carrying amount of goodwill, and no gain or loss is recognized in profit or loss.

The Company now owns the worldwide rights to its small molecule iNKT agonists, including lead programs PORT-2 and PORT-3. Under the terms of the Share Exchange Agreement, each Seller sold to the Company, and the Company acquired from each Seller, legal and beneficial ownership of the number of iOx shares held by each Seller, free and clear of any share encumbrances, in exchange for the issuance in an aggregate of 1,070,000 Portage ordinary shares to be allocated among the Sellers based upon their relative ownership. As a result of the Share Exchange Agreement, the Company owns 100% of the issued and outstanding shares of iOx.

As additional consideration for the sale of the iOx shares to the Company under the Share Exchange Agreement, the Sellers shall have the contingent right to receive additional shares ("Earnout Shares") from the Company having an aggregate value equal to $25 million calculated at the Per Share Earnout Price, as defined in the Share Exchange Agreement, upon the achievement of certain milestones defined as the dosing of the first patient in a Phase 3 clinical trial for either PORT-2 (IMM60 iNKT cell activator/agonist) or PORT-3 (PLGA-nanoparticle formulation of IMM60 combined with a NY-ESO-1 peptide vaccine). The Company shall have the option, in its sole and absolute discretion, to settle the Earnout Shares in cash.

#### Off-balance Sheet Arrangements
As of December 31, 2022 and March 31, 2022, the Company did not have any off-balance sheet arrangements, including any relationships with unconsolidated entities or financial partnership to enhance perceived liquidity.

**Transactions with Related Parties**

Significant related party transactions are detailed in Note 18, "Related Party Transactions," to the unaudited condensed consolidated interim financial statements for the three and nine months ended December 31, 2022.

#### Financial and Derivative Instruments
The Company's financial instruments recognized in the Company's condensed consolidated interim statements of financial position consist of the following:

Fair value estimates are made at a specific point in time, based on relevant market information and information about financial instruments. These estimates are subject to and involve uncertainties and matters of significant judgment, therefore cannot be determined with precision. Changes in assumptions could significantly affect the estimates.

The following table summarizes the Company's financial instruments as of December 31, 2022 and March 31, 2022:

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **As of December 31, 2022** | **As of December 31, 2022** | **As of March 31, 2022** | **As of March 31, 2022** |
| (In thousands) | **Amortized Cost** | **Fair Value through Other Comprehensive <br>Income ("FVTOCI")** | **Amortized Cost** | **FVTOCI** |
| **<u>Financial assets</u>** |  |  |  |  |
| **Cash and cash equivalents** | $**13104** | $**–** | $23352 | $– |
| **Prepaid expenses and other receivables** | $**1786** | $**–** | $1480 | $– |
| **Convertible note receivable, including accrued interest** | $**–** | **642** | $– | $– |
| **Investments** | $**–** | **4768** | $– | $9082 |

---

---

| | | | | |
|:---|:---|:---|:---|:---|
|  | **Amortized Cost** | **Fair Value through Profit or Loss ("FVTPL")** | **Amortized Cost** | **FVTPL** |
| **<u>Financial liabilities</u>** |  |  |  |  |
| **Accounts payable and accrued liabilities** | $**2422** | $**–** | $750 | $– |
| **Warrant liability** | $**–** | $**–** | $– | $33 |
| **Deferred purchase price payable - Tarus** | $**–** | $**8876** | $– | $– |
| **Deferred obligation - iOx milestone** | $**–** | $**5568** | $– | $– |

---

A summary of the Company's risk exposures as it relates to financial instruments are reflected below.

***Fair value of Financial Instruments***

The Company's financial assets and liabilities are comprised of cash and cash equivalents, receivables and investments in equities and private entities, accounts payable, warrant liability and unsecured notes payable.

The Company classifies the fair value of these transactions according to the following fair value hierarchy based on the amount of observable inputs used to value the instrument:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Level 1 – Values are based on unadjusted quoted prices available in active markets for identical assets or liabilities as of
the reporting date.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Level 2 – Values are based on inputs, including quoted forward prices for commodities, time value and volatility factors, which
can be substantially observed or corroborated in the marketplace. Prices in Level 2 are either directly or indirectly observable as of
the reporting date.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Level 3 – Values are based on prices or valuation techniques that are not based on observable market data. Investments are classified
as Level 3 financial instrument.

Assessment of the significance of a particular input to the fair value measurement requires judgment and may affect the placement within the fair value hierarchy.

Management has assessed that the fair values of cash and cash equivalents, other receivables and accounts payable approximate their carrying amounts largely due to the short-term maturities of these instruments.

The following methods and assumptions were used to estimate their fair values:

**Convertible Note Receivable:** The fair value of the Stimunity Convertible Note receivable denominated in euros at initial recognition is the transaction price for the instrument adjusted for the effect of the currency translation rate on the reporting date (Level 3). The Company recognized an unrealized gain through OCI on the change in fair value of the Stimunity Convertible Note receivable of $0.29 million for the three and nine months ended December 31, 2022.

**Investment in Intensity**: Fair value of the asset is determined by considering other comparable equity funding transactions by Intensity with unrelated investors (Level 3).

**Accrued Equity Issuable:** The fair value is estimated based on the average of the quoted market prices for the period in which the shares were earned (Level 1).

**Warrant Liability**: The fair value is estimated using a Black-Scholes model (Level 3).

**Deferred Purchase Price Payable - Tarus:** The fair value is the estimated value of a future contingent obligation based upon a fair value analysis performed in accordance with IFRS 3 at acquisition date, adjusted at each reporting date for any change in fair value (Level 3). The fair value was determined using the Income Approach and was based upon the analysis on the Tarus clinical plan, the timing of development events and the probabilities of success determined primarily based upon empirical third party data and Company experience, as well as the relevant cost of capital. The Company recorded a (loss) from the change (increase) in fair value of the liability of $0.354 million and $0.338 million for the three and nine months ended December 31, 2022, respectively.

**Deferred Obligation - iOx Milestone:** The fair value is the estimated value of a future contingent obligation based upon a fair value analysis performed in accordance with IFRS 3 as of July 18, 2022, the date of the Share Exchange Agreement, adjusted at each reporting date for any change in fair value (Level 3). The fair value was determined using the Income Approach and based on factors including the clinical plan, the timing of development events and the probabilities of success determined primarily based upon empirical third party data and Company experience, as well as the relevant cost of capital. The Company recorded a (loss) from the change (increase) in fair value of the liability of $0.144 million and $0.090 million for the three and nine months ended December 31, 2022, respectively.

There have been no transfers between levels of the fair value hierarchy for the nine months ended December 31, 2022 and the year ended March 31, 2022.

The Company's financial instruments are exposed to certain financial risks: Credit Risk, Liquidity Risk and Foreign Currency Risk.

***Credit Risk***

 ****

Credit risk is the risk of loss associated with a counterparty's inability to fulfil its payment obligations. The credit risk is attributable to various financial instruments, as noted below. The credit risk is limited to the carrying value as reflected in the Company's condensed consolidated interim statements of financial position.

 ****

***Cash and cash equivalents*.** Cash and cash equivalents comprise cash on hand and on-demand deposits that are readily convertible to a known amount of cash with three months or less from date of acquisition and are subject to an insignificant risk of change in value. As of December 31, 2022 and March 31, 2022, cash equivalents was comprised of a money market account with maturities less than 90 days from the date of purchase. Cash and cash equivalents are held with major international financial institutions and therefore the risk of loss is minimal.

***Liquidity Risk***

Liquidity risk is the risk that the Company will encounter difficulty in satisfying financial obligations as they become due.

The Company's approach to managing liquidity is to ensure, as far as possible, that it will have sufficient liquidity to meet its liabilities when due, under both normal and stressed conditions without incurring unacceptable losses or risking harm to the Company's reputation. The Company holds sufficient cash and cash equivalents to satisfy obligations under accounts payable and accruals.

The Company monitors its liquidity position regularly to assess whether it has the funds necessary to meet its operating needs and needs for investing in new projects. The Company believes that it has sufficient funding to finance the committed drug development work, apart from meeting its operational needs for the foreseeable future.

However, as a biotech company at an early stage of development and without significant internally generated cash flows, there are inherent liquidity risks, including the possibility that additional financing may not be available to the Company, or that actual drug development expenditures may exceed those planned. The current uncertainty in global markets could have an impact on the Company's future ability to access capital on terms that are acceptable to the Company. There can be no assurance that required financing will be available to the Company.

***Foreign Currency Risk***

While the Company operates in various jurisdictions, substantially all of the Company's transactions are denominated in the U.S. Dollar, except the deferred tax liability in the U.K. settleable in British pound sterling and the Stimunity Convertible Note receivable settleable in euros.

**Use of Estimates and Judgments**

The preparation of the condensed consolidated interim financial statements in conformity with IFRS requires management to make judgments, estimates and assumptions that affect the application of accounting policies and the reported amounts of assets, liabilities, income and expenses. Actual results may differ from these estimates.

Estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognized in the period in which the estimates are revised and in any future periods affected.

Significant areas where estimates are made include valuation of financial instruments (including the convertible note receivable), deferred tax assets, deferred tax liability, R&D costs, fair value used for acquisition of intangible assets, contingent consideration assumed and measurement of share-based compensation. Significant areas where critical judgments are applied include assessment of impairment of investments and goodwill and the determination of the accounting acquirer and acquiree in the business combination accounting.

**New Accounting Standards, Interpretations and Amendments**

The Company is also unaware of any applicable but not-yet-adopted standards that are expected to materially affect the Company's financial statements for future periods.

#### Internal Controls Over Financial Reporting
The management of the Company, including the Chief Executive Officer and Chief Financial Officer, is responsible for establishing and maintaining adequate internal controls over financial reporting (as defined in Rule 13a-15(f) under the Securities Exchange Act of 1934, as amended). The Company's internal control system was designed to provide reasonable assurance to the Company's management and the Company's Board of Directors regarding the reliability of financial reporting and preparation and fair presentation of published financial statements for external purposes in accordance with IFRS. Internal control over financial reporting includes those policies and procedures that:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1. pertain to the maintenance of records that in reasonable detail accurately and fairly reflect the transactions and dispositions of
the assets of the Company;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2. provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance
with IFRS, and that receipts and expenditures of the Company are being made only in accordance with authorizations of management and the
directors of the Company; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3. provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or disposition of the Company's
assets that could have a material effect on the financial statements.

All internal control systems, no matter how well designed, have inherent limitations. Therefore, even those systems determined to be effective can provide only reasonable assurance with respect to financial statement preparation and presentation. Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions or that the degree of compliance with the policies or procedures may deteriorate.

Management assessed the effectiveness of the Company's internal control over financial reporting as of December 31, 2022. In making this assessment, it used the criteria established in Internal Control - Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission. Based on the evaluation under these criteria, management identified material weaknesses in the Company's internal controls over financial reporting and, as a result, management concluded that the Company's internal control over financial reporting was not effective as of December 31, 2022.

Management identified the following material weaknesses in our internal control over financial reporting.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Management was unable to perform an effective risk assessment or monitor internal controls
over financial reporting;

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· Management lacks the number of skilled persons that it requires given the complexity of the
reporting requirements that it has to make, which more specifically include the staff and expertise to (i) properly segregate duties
and perform oversight of work performed and to perform compensating controls over the finance and accounting functions, (ii) establish
and perform fair value estimates or subsequently monitor fluctuations in fair value estimates, and (iii) apply complex accounting principles,
including those relating to business combination accounting, income taxes and fair value estimates; and

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;· There are insufficient written policies and procedures in place to ensure the correct application
of accounting and financial reporting with respect to the current requirements of IFRS and SEC disclosure requirements, some of which
specifically relate to investment accounting and fair value measures, assessment of in-process R&D assets, share-based payments,
carrying amounts of goodwill and intangible assets and business combination accounting.

#### Public Securities Filings
Additional information, including the Company's annual information in the Annual Report on Form 20-F, is filed with the Canadian Securities Administrators at www.sedar.com and with the United States Securities and Exchange Commission at www.edgar.com.