# EDGAR Filing Document

**Accession Number:** 0001117480
**File Stem:** 0001209191-23-004146
**Filing Date:** 2023-1
**Character Count:** 6633
**Document Hash:** bb3632ce2cc4057dfd836b93bd783394
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001209191-23-004146.hdr.sgml**: 20230119

**ACCESSION NUMBER**: 0001209191-23-004146

**CONFORMED SUBMISSION TYPE**: 4

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20230117

**FILED AS OF DATE**: 20230119

**DATE AS OF CHANGE**: 20230119

**REPORTING-OWNER**: 

**OWNER DATA:**
- **COMPANY CONFORMED NAME:** Melemed Allen S.
- **CENTRAL INDEX KEY:** 0001815774

**FILING VALUES:**
- **FORM TYPE:** 4
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-35867
- **FILM NUMBER:** 23538783

**MAIL ADDRESS:**
- **STREET 1:** C/O CHIMERIX, INC.
- **STREET 2:** 2505 MERIDIAN PARKWAY, SUITE 100
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27713
**ISSUER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** CHIMERIX INC
- **CENTRAL INDEX KEY:** 0001117480
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **IRS NUMBER:** 330903395
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**BUSINESS ADDRESS:**
- **STREET 1:** 2505 MERIDIAN PARKWAY, SUITE 100
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27713
- **BUSINESS PHONE:** 919.806.1074

**MAIL ADDRESS:**
- **STREET 1:** 2505 MERIDIAN PARKWAY, SUITE 100
- **CITY:** DURHAM
- **STATE:** NC
- **ZIP:** 27713

### UNITED STATES SECURITIES AND EXCHANGE COMMISSION
**Washington, D.C. 20549**

## FORM 4

### STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

[ ] Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

---

| | | |
|:---|:---|:---|
| **1. Name and Address of Reporting Person**<sup>*</sup><br>Melemed Allen S.<br><sub>(Last) (First) (Middle)</sub><br>C/O CHIMERIX, INC.<br>2505 MERIDIAN PARKWAY, SUITE 100<br><sub>(Street)</sub><br>DURHAM, NC 27713<br><sub>(City) (State) (Zip)</sub> | **3. Date of Earliest Transaction (Month/Day/Year)**<br>2023-01-17 | **5. Relationship of Reporting Person(s) to Issuer**<br>(Check all applicable)<br>[ ] Director [ ] 10% Owner<br>[X] Officer (give title below) [ ] Other (specify below)<br>_Chief Medical Officer_ |
| **2. Issuer Name and Ticker or Trading Symbol**<br>CHIMERIX INC [ CMRX ] | **4. If Amendment, Date of Original Filed (Month/Day/Year)**<br>  | **6. Individual or Joint/Group Filing (Check Applicable Line)**<br>[X] Form filed by One Reporting Person<br>[ ] Form filed by More than One Reporting Person |

---

## Table I - Non-Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | 3. Transaction Code (V) | 3. Transaction Code (V) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 4. Securities Acquired (A) or Disposed of (D) | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| 1. Title of Security | 2. Transaction Date | 2A. Deemed Execution Date | Code | V | Amount | (A) or (D) | Price | 5. Amount of Securities Beneficially Owned | 6. Ownership Form | 7. Nature of Indirect Beneficial Ownership |
| Common Stock | 2023-01-17 |  | A |  | 25740<sup>(1)</sup> | A | $0.00 | 47887<sup>(2)</sup> | D |  |

---

## Table II - Derivative Securities

---

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | 4. Transaction Code (V) | 4. Transaction Code (V) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 5. Number of Derivative Securities Acquired (A) or Disposed of (D) | 6. Date Exercisable and Expiration Date | 6. Date Exercisable and Expiration Date | 7. Title and Amount of Underlying Securities | 7. Title and Amount of Underlying Securities | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| 1. Title of Derivative Security | 2. Conversion or Exercise Price | 3. Transaction Date | 3A. Deemed Execution Date | Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares | 8. Price of Derivative Security | 9. Number of Derivative Securities Beneficially Owned | 10. Ownership Form | 11. Nature of Indirect Beneficial Ownership |
| Stock Option (Right to Buy) | $1.97 | 2023-01-17 |  | A |  | 154260 |  | <sup>(3)</sup> | 2033-01-16 | Common Stock | 154260 | $0.00 | 154260 | D |  |

---

### Footnotes:

(1) The shares being reported are being issued pursuant to restricted stock unit awards ("RSUs"), each one of which represents a contingent right to receive one share of the Issuer's common stock. 6,435 shares subject to the RSUs will vest on the one-year anniversary of the date of grant, 6,435 shares subject to the RSUs will vest on the second-year anniversary of the date of grant, 6,435 shares subject to the RSUs will vest on the third-year anniversary of the date of grant, and 6,435 shares subject to the RSUs will vest on the fourth-year anniversary of the date of grant.

(2) Includes 4,345 shares acquired under the Issuer's Employee Stock Purchase Plan (the "ESPP") on March 10, 2021, 6,414 shares acquired under the ESPP on September 10, 2021, 6,707 shares acquired under the ESPP on March 10, 2022 and 4,681 shares acquired under the ESPP on September 9, 2022.

(3) 1/48th of the shares subject to the option vest in equal monthly installments over a four year period following the date of grant.

**Signature:** /s/ Michael Alrutz, Attorney-in-Fact  
**Date:** 2023-01-19

### Remarks:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

**Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.**