# EDGAR Filing Document

**Accession Number:** 0001002624
**File Stem:** 0001099263-26-006598
**Filing Date:** 2026-5
**Character Count:** 103205
**Document Hash:** 3e8731bd64639f2e085287f486a204fc
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001099263-26-006598.hdr.sgml**: 20260528

**ACCESSION NUMBER**: 0001099263-26-006598

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20260331

**FILED AS OF DATE**: 20260528

**DATE AS OF CHANGE**: 20260528

**PERIOD START**: 20261231

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** T. Rowe Price Health Sciences Fund, Inc.
- **CENTRAL INDEX KEY:** 0001002624

**ORGANIZATION NAME:**
- **EIN:** 521952906
- **STATE OF INCORPORATION:** MD
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-07381
- **FILM NUMBER:** 261035239

**BUSINESS ADDRESS:**
- **STREET 1:** 1307 POINT STREET
- **CITY:** BALTIMORE
- **STATE:** MD
- **ZIP:** 21231
- **BUSINESS PHONE:** 410-345-2000

**MAIL ADDRESS:**
- **STREET 1:** 1307 POINT STREET
- **CITY:** BALTIMORE
- **STATE:** MD
- **ZIP:** 21231

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PRICE T ROWE HEALTH SCIENCES FUND INC
- **DATE OF NAME CHANGE:** 19980513

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PRICE T ROWE HEALTH & LIFE SCIENCES FUND INC
- **DATE OF NAME CHANGE:** 19951023

## Series and Classes Contracts Data

### T. Rowe Price Health Sciences Fund, Inc. (Series ID: S000002088)

| Class ID   | Class Name                                 | Ticker Symbol   |
|:---|:---|:---|
| C000005456 | T. Rowe Price Health Sciences Fund, Inc.   | PRHSX           |
| C000169937 | T. Rowe Price Health Sciences Fund-I Class | THISX           |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** T. ROWE PRICE HEALTH SCIENCES FUND, INC.

- **b. Investment Company Act file number:** 811-07381

- **c. CIK number of Registrant:** 0001002624

- **d. LEI of Registrant:** 549300ELV6FPY6UQBJ78

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 1307 Point Street

  - **City:** Baltimore

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 21231

  - **Telephone number:** 410-345-2000

**Item A.2. Information about the Series.**

- **a. Name of Series:** T. Rowe Price Health Sciences Fund, Inc.

- **b. EDGAR series identifier (if any):** S000002088

- **c. LEI of Series:** 66LP7EMLZS5S33LWIH41

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2026-12-31

- **b. Date as of which information is reported:** 2026-03-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $10905505234.55

**Total Liabilities:** $12192681.43

**Net Assets:** $10893312553.12

**Assets Attributable to Miscellaneous Securities:** $524146830.04

**Stand-by Commitments:** $4381780.00

**Cash Not Reported:** $924137.00

**Currency Risk Metrics (dv01):**

- 

**Credit Spread Risk - Investment Grade (dv01):**

- **3-Month:** 0.000000 | **1-Year:** 0.000000 | **5-Year:** 0.000000 | **10-Year:** 0.000000 | **30-Year:** 0.000000

**Credit Spread Risk - Non-Investment Grade (dv01):**

- **3-Month:** 0.000000 | **1-Year:** 0.000000 | **5-Year:** 0.000000 | **10-Year:** 0.000000 | **30-Year:** 0.000000

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000005456 | -0.98%               | 0.64%                | -5.91%               |
| Class ID C000169937 | -0.97%               | 0.65%                | -5.90%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $366486223.17            | $-478141557.65                             |
| Month 2  | $74638075.47             | $-623268.69                                |
| Month 3  | $111170729.10            | $-807605526.49                             |

### Schedule of Portfolio Investments

| Name                                       | Title                                              | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)    | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| EXACT SCIENCES CMO MILESTONE PP            | - EXACT SCIENCES CMO MILESTONE PP                  | CUSIP: 000000000<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |   3726272 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ABBVIE INC                                 | ABBVIE INC                                         | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |   1423341 | NS      | $309562434.09  | 2.84%             |  |  |  | No            |                  1 | On Loan: No      |
| ABIVAX SA-ADR                              | ABIVAX SA                                          | CUSIP: 00370M103<br>LEI: 969500D8TMNB184OJU95 | Long             | EC               | CORP              | FR        |    407954 | NS      | $45425677.90   | 0.42%             |  |  |  | No            |                  1 | On Loan: No      |
| ADLAI NORTYE LTD-ADR                       | ADLAI NORTYE LTD                                   | CUSIP: 00704R109<br>LEI: 54930009TDXE4YQVKU60 | Long             | EC               | CORP              | KY        |    219665 | NS      | $1520081.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| AFFINIVAX AFX3772 MILESTONE EVENT PP       | AFFINIVAX AFX3772 MILESTONE EVENT PP               | CUSIP: TC2HD0ET2<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   7349672 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AFFINIVAX EXPENSE FUND PP                  | AFFINIVAX EXPENSE FUND PP                          | CUSIP: TC929D1E2<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12445 | NS      | $11563.06      | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AFFINIVAX NEXT GEN PROD MILESTON EVNT PP   | AFFINIVAX NEXT GEN PROD MILESTON EVNT PP           | CUSIP: TC7BEY6E7<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   7349672 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AGIOS PHARMACEUTICALS INC                  | AGIOS PHARMACEUTICALS INC                          | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |     70221 | NS      | $2375576.43    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| AKTIS ONCOLOGY INC                         | AKTIS ONCOLOGY INC                                 | CUSIP: 01021M104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    333745 | NS      | $5970698.05    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| ALIGNMENT HEALTHCARE INC                   | ALIGNMENT HEALTHCARE INC                           | CUSIP: 01625V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1475585 | NS      | $25999807.70   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| ALLOGENE THERAPEUTICS INC                  | ALLOGENE THERAPEUTICS INC                          | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   3830998 | NS      | $9347635.12    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| ALNYLAM PHARMACEUTICALS INC                | ALNYLAM PHARMACEUTICALS INC                        | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |    531894 | NS      | $175987767.78  | 1.62%             |  |  |  | No            |                  1 | On Loan: No      |
| ALTO NEUROSCIENCE INC                      | ALTO NEUROSCIENCE INC                              | CUSIP: 02157Q109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    268280 | NS      | $6030934.40    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| ALUMIS INC                                 | ALUMIS INC                                         | CUSIP: 022307102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1188623 | NS      | $26185364.69   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| AMGEN INC                                  | AMGEN INC                                          | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |    303722 | NS      | $106864585.70  | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| ANNEXON INC                                | ANNEXON INC                                        | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    176618 | NS      | $978463.72     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| APOGEE THERAPEUTICS INC                    | APOGEE THERAPEUTICS INC                            | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    555098 | NS      | $46722598.66   | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| ARBOR BIO SERIES B CVT PFD STOCK PP        | ARBOR BIO SERIES B CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    532759 | NS      | $2834277.88    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ARBOR BIO SERIES C CVT PFD STOCK PP        | ARBOR BIO SERIES C CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    322096 | NS      | $1713550.72    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ARGENX SE - ADR                            | ARGENX SE                                          | CUSIP: 04016X101<br>LEI: 7245009C5FZE6G9ODQ71 | Long             | EC               | CORP              | NL        |    435310 | NS      | $317885127.50  | 2.92%             |  |  |  | No            |                  1 | On Loan: No      |
| ARROWHEAD PHARMACEUTICALS INC              | ARROWHEAD PHARMACEUTICALS INC                      | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |    301270 | NS      | $18889629.00   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| ARSENAL BIOSCIENCES SER C CVT PFD PP       | ARSENAL BIOSCIENCES SER C CVT PFD PP               | CUSIP: TC5YX3EI8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    724394 | NS      | $13459240.52   | 0.12%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ASCENDIS PHARMA A/S - ADR                  | ASCENDIS PHARMA A/S                                | CUSIP: 04351P101<br>LEI: 549300B66JN3W3J8GH73 | Long             | EC               | CORP              | DK        |    676173 | NS      | $154661050.29  | 1.42%             |  |  |  | No            |                  1 | On Loan: No      |
| ASTRAZENECA PLC                            | ASTRAZENECA PLC                                    | CUSIP: 000000000<br>LEI: PY6ZZQWO2IZFZC3IOL08 | Long             | EC               | CORP              | GB        |   1751235 | NS      | $345378566.70  | 3.17%             |  |  |  | No            |                  1 | On Loan: No      |
| ATRIUM THERAPEUTICS INC                    | ATRIUM THERAPEUTICS INC                            | CUSIP: 04965N104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    666325 | NS      | $8908765.25    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| AURA BIOSCIENCES INC                       | AURA BIOSCIENCES INC                               | CUSIP: 05153U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    221135 | NS      | $1479393.15    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| AVALYN PHARMA SER C-1 CVT PFD STOCK PP     | AVALYN PHARMA SER C-1 CVT PFD STOCK PP             | CUSIP: TC6KYIDL7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   8436161 | NS      | $6717715.00    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AVALYN PHARMA SER D CVT PFD STOCK PP       | AVALYN PHARMA SER D CVT PFD STOCK PP               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1666360 | NS      | $1326922.47    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| AXSOME THERAPEUTICS INC                    | AXSOME THERAPEUTICS INC                            | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |    163910 | NS      | $27704068.20   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Aktis Oncology Inc. Lockup Shs PP          | Aktis Oncology, Inc. IPO                           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    724914 | NS      | $12968711.46   | 0.12%             |  |  |  | Yes           |                  2 | On Loan: No      |
| BEAM THERAPEUTICS INC                      | BEAM THERAPEUTICS INC                              | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1093992 | NS      | $26069829.36   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| BELITE BIO INC - ADR                       | BELITE BIO INC                                     | CUSIP: 07782B104<br>LEI: 984500BD54036BOEAE79 | Long             | EC               | CORP              | KY        |    207862 | NS      | $33141517.28   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| BEONE MEDICINES LTD-ADR                    | BEONE MEDICINES LTD                                | CUSIP: 07725L102<br>LEI: 549300JFUK6FRD5MH739 | Long             | EC               | CORP              | KY        |     49225 | NS      | $14618348.25   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| BEONE MEDICINES LTD                        | BEONE MEDICINES LTD                                | CUSIP: 000000000<br>LEI: 549300JFUK6FRD5MH739 | Long             | EC               | CORP              | CH        |   5757796 | NS      | $129161256.95  | 1.19%             |  |  |  | No            |                  2 | On Loan: No      |
| BETA BIONICS INC                           | BETA BIONICS INC                                   | CUSIP: 08659B102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113126 | NS      | $1133522.52    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| BICARA THERAPEUTICS INC                    | BICARA THERAPEUTICS INC                            | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    642514 | NS      | $12779603.46   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| BICYCLE THERAPEUTICS PLC-ADR               | BICYCLE THERAPEUTICS PLC                           | CUSIP: 088786108<br>LEI: 213800XKUI6R7GKC3E43 | Long             | EC               | CORP              | GB        |    739251 | NS      | $3430124.64    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| BILLIONTOONE INC CL A                      | BILLIONTOONE INC                                   | CUSIP: 090168105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    264475 | NS      | $20877656.50   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| BIO-RAD LABORATORIES-A                     | BIO-RAD LABORATORIES INC                           | CUSIP: 090572207<br>LEI: 549300ZC1GPV35XYDK53 | Long             | EC               | CORP              | US        |     60717 | NS      | $16924863.75   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| BIOHAVEN LTD                               | BIOHAVEN LTD                                       | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | VG        |   1228554 | NS      | $10393566.84   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Blue Marlin Therapeutics Common Stock PP   | BLUE MARLIN THERAPEUTICS COMMON STOCK PP           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      1803 | NS      | $180.30        | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| BOSTON SCIENTIFIC CORP                     | BOSTON SCIENTIFIC CORP                             | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |   1603771 | NS      | $100636630.25  | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| BridgeBio Oncology Therapeutics Inc        | BRIDGEBIO ONCOLOGY THERAPEUTICS INC                | CUSIP: 107924102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    333485 | NS      | $2984690.75    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| BRIDGEBIO PHARMA INC                       | BRIDGEBIO PHARMA INC                               | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |    864149 | NS      | $64171704.74   | 0.59%             |  |  |  | No            |                  1 | On Loan: No      |
| BRIGHTSPRING HEALTH SERVICES               | BRIGHTSPRING HEALTH SERVICES INC                   | CUSIP: 10950A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   2514077 | NS      | $107124820.97  | 0.98%             |  |  |  | No            |                  1 | On Loan: No      |
| Cabaletta Bio Common WTS 09/26 PP          | CABALETTA BIO COMMON WTS 09/26 PP                  | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1694355 | NS      | $321927.45     | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| CABALETTA BIO INC                          | CABALETTA BIO INC                                  | CUSIP: 12674W109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    608501 | NS      | $1636867.69    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CAPSULE CORP SERIES 1-D CVT PFD STOCK      | CAPSULE CORP SERIES 1-D CVT PFD STOCK              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    853213 | NS      | $861745.13     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CAPSULE CORP SERIES E CVT PFD STOCK PP     | CAPSULE CORP SERIES E CVT PFD STOCK PP             | CUSIP: TC0YJ3TD4<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    906656 | NS      | $915722.56     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CARDINAL HEALTH INC                        | CARDINAL HEALTH INC                                | CUSIP: 14149Y108<br>LEI: CCU46N3GJMF4OK4N7U60 | Long             | EC               | CORP              | US        |    348232 | NS      | $73584903.92   | 0.68%             |  |  |  | No            |                  1 | On Loan: No      |
| CARIS LIFE SCIENCES INC                    | CARIS LIFE SCIENCES INC                            | CUSIP: 142152107<br>LEI: 549300LX5LO78M5VPY43 | Long             | EC               | CORP              | US        |   1909867 | NS      | $34148421.96   | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| CELCUITY INC                               | CELCUITY INC                                       | CUSIP: 15102K100<br>LEI: 25490070W7UU7W2SEY87 | Long             | EC               | CORP              | US        |    531000 | NS      | $60608340.00   | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| CELLANOME SERIES A CVT PFD STOCK PP        | CELLANOME SERIES A CVT PFD STOCK PP                | CUSIP: TC13MXKE8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1993387 | NS      | $17342466.90   | 0.16%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CELLDEX THERAPEUTICS INC                   | CELLDEX THERAPEUTICS INC                           | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |    422316 | NS      | $13395863.52   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| CENCORA INC                                | CENCORA INC                                        | CUSIP: 03073E105<br>LEI: AI8GXW8LG5WK7E9UD086 | Long             | EC               | CORP              | US        |    179717 | NS      | $56456298.38   | 0.52%             |  |  |  | No            |                  1 | On Loan: No      |
| CENTENE CORP                               | CENTENE CORP                                       | CUSIP: 15135B101<br>LEI: 549300Z7JJ4TQSQGT333 | Long             | EC               | CORP              | US        |    529331 | NS      | $17330296.94   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| CENTESSA PHARMACEUTICALS-ADR               | CENTESSA PHARMACEUTICALS PLC                       | CUSIP: 152309100<br>LEI: 213800GIDAARDSKOI827 | Long             | EC               | CORP              | GB        |   1367577 | NS      | $54320158.44   | 0.50%             |  |  |  | No            |                  1 | On Loan: No      |
| CG ONCOLOGY INC                            | CG ONCOLOGY INC                                    | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1108573 | NS      | $75028220.64   | 0.69%             |  |  |  | No            |                  1 | On Loan: No      |
| CHARLES RIVER LABORATORIES                 | CHARLES RIVER LABORATORIES INTERNATIONAL INC       | CUSIP: 159864107<br>LEI: 549300BSQ0R4UZ5KX287 | Long             | EC               | CORP              | US        |     79633 | NS      | $13736692.50   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| NCHROMA BIO SER I CVT PFD STOCK PP         | CHROMA MEDICINE SER I CVT PFD STOCK PP             | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   7683800 | NS      | $7683800.00    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CHROMACODE INC PP                          | CHROMACODE INC PP                                  | CUSIP: TC43UPY99<br>LEI: N/A                  | Long             | EC               | CORP              | US        |       626 | NS      | $3029.71       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Chromacode INC SER AA CVT PFD STK PP       | CHROMACODE INC SER AA CVT PFD STK PP               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     36845 | NS      | $178322.43     | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CHUGAI PHARMACEUTICAL CO LTD               | CHUGAI PHARMACEUTICAL CO LTD                       | CUSIP: 000000000<br>LEI: 529900T9LAII161DCN95 | Long             | EC               | CORP              | JP        |   1141000 | NS      | $62924419.81   | 0.58%             |  |  |  | No            |                  2 | On Loan: No      |
| CIGNA GROUP/THE                            | CIGNA GROUP/THE                                    | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |    300304 | NS      | $80106092.00   | 0.74%             |  |  |  | No            |                  1 | On Loan: No      |
| CLEAR LABS SER D CVT PFD STOCK PP          | CLEAR LABS SER D CVT PFD STOCK PP                  | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    379601 | NS      | $1183026.52    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CLEAR LABS SERIES C CVT PFD PP             | CLEAR LABS SERIES C CVT PFD PP                     | CUSIP: TC385IBS6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   3830773 | NS      | $12119799.62   | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CLEERLY SER C CVT PFD STK PP               | CLEERLY SER C CVT PFD STK PP                       | CUSIP: TC1A1CZJ4<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    586029 | NS      | $10284808.95   | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Climb Bio Inc                              | CLIMB BIO INC                                      | CUSIP: 28658R106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1468417 | NS      | $10058656.45   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| COGENT BIOSCIENCES INC                     | COGENT BIOSCIENCES INC                             | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    326181 | NS      | $12554706.69   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| COLOR HEALTH SR D CVT PFD STOCK PP         | COLOR HEALTH SER D CVT PFD STOCK PP                | CUSIP: TC1HL9RU8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    296922 | NS      | $5697933.18    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| COLOR HEALTH SR D-1 CVT PFD STOCK PP       | COLOR HEALTH SERIES D-1 CVT PFD STOCK PP           | CUSIP: TC3KSMZE0<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    438696 | NS      | $5913622.08    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| COLOR HEALTH SERIES E CVT PFD STOCK PP     | COLOR HEALTH SERIES E CVT PFD STOCK PP             | CUSIP: TC4SC4HB5<br>LEI: N/A                  | Long             | EP               | CORP              | US        |     44149 | NS      | $1810109.00    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| CORVUS PHARMACEUTICALS INC                 | CORVUS PHARMACEUTICALS INC                         | CUSIP: 221015100<br>LEI: 549300I3AVJ8F75NCX65 | Long             | EC               | CORP              | US        |    725099 | NS      | $10608198.37   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| CRESCENT BIOPHARMA INC                     | CRESCENT BIOPHARMA INC                             | CUSIP: 000000000<br>LEI: 549300TZ84FFU2J2J459 | Long             | EC               | CORP              | KY        |    221065 | NS      | $4060964.05    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| CRINETICS PHARMACEUTICALS IN               | CRINETICS PHARMACEUTICALS INC                      | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |   1094456 | NS      | $39750641.92   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc                  | CULLINAN THERAPEUTICS INC                          | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    686764 | NS      | $9758916.44    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| CVS HEALTH CORP                            | CVS HEALTH CORP                                    | CUSIP: 126650100<br>LEI: 549300EJG376EN5NQE29 | Long             | EC               | CORP              | US        |   1310339 | NS      | $94108546.98   | 0.86%             |  |  |  | No            |                  1 | On Loan: No      |
| CYTOKINETICS INC                           | CYTOKINETICS INC                                   | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |    663136 | NS      | $43707293.76   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| DANAHER CORP                               | DANAHER CORP                                       | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |   1175471 | NS      | $222869301.60  | 2.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Delfi Diagnostics CVT Prom Note PP         | DELFI DIAGNOSTICS CVT PROM NOTE PP                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | DBT              | CORP              | US        |   1732158 | PA      | $1732157.76    | 0.02%             | 2027-01-29      | None          | 0.00%                 | Yes           |                  3 | On Loan: No      |
| DELFI DIAGNOSTICS SR A CVT PFD STOCK PP    | DELFI DIAGNOSTICS SR A CVT PFD STOCK PP            | CUSIP: TC0LOSSE0<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   3426868 | NS      | $13399053.88   | 0.12%             |  |  |  | Yes           |                  3 | On Loan: No      |
| DELFI DIAGNOSTICS SR B CVT PFD STOCK PP    | DELFI DIAGNOSTICS SR B CVT PFD STOCK PP            | CUSIP: TC7ZV25B2<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1853138 | NS      | $7245769.58    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| DENALI THERAPEUTICS INC                    | DENALI THERAPEUTICS INC                            | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |    468129 | NS      | $8988076.80    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| DIANTHUS THERAPEUTICS INC                  | DIANTHUS THERAPEUTICS INC                          | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |    482750 | NS      | $40512380.00   | 0.37%             |  |  |  | No            |                  1 | On Loan: No      |
| DISC MEDICINE INC                          | DISC MEDICINE INC                                  | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    186605 | NS      | $11931523.70   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| DNA SCRIPT SERIES C CVT PFD STOCK PP       | DNA SCRIPT SERIES C CVT PFD STOCK PP               | CUSIP: TC3XW4UW2<br>LEI: 8945001SCRZOZAUEFH64 | Long             | EP               | CORP              | FR        |     25201 | NS      | $2609920.40    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Deepsight Tech Inc SER C CVT PFD PP        | Deepsight Tech Inc SER C CVT PFD PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    342294 | NS      | $4378727.54    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| EDWARDS LIFESCIENCES CORP                  | EDWARDS LIFESCIENCES CORP                          | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |    562277 | NS      | $45027142.16   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| EIKON THERAPEUTICS INC                     | EIKON THERAPEUTICS INC                             | CUSIP: 282564103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    349098 | NS      | $3693456.84    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ELEMENT BIOSCIENCES SER C CVT PFD STOCK PP | ELEMENT BIOSCIENCES SER C CVT PFD STOCK            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    861217 | NS      | $5907948.62    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ELEMENT BIOSCIENCES SER D CVT PFD PP       | ELEMENT BIOSCIENCES SER D CVT PFD PP               | CUSIP: TC3OATBR3<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    281354 | NS      | $1561514.70    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ELEMENT BIOSCIENCES SER D-1 CVT PFD PP     | ELEMENT BIOSCIENCES SER D-1 CVT PFD PP             | CUSIP: TC141T8S1<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    281354 | NS      | $1561514.70    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ELEVANCE HEALTH INC                        | ELEVANCE HEALTH INC                                | CUSIP: 036752103<br>LEI: 8MYN82XMYQH89CTMTH67 | Long             | EC               | CORP              | US        |    244278 | NS      | $71512384.50   | 0.66%             |  |  |  | No            |                  1 | On Loan: No      |
| ELI LILLY & CO                             | ELI LILLY & CO                                     | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |   1200478 | NS      | $1104163650.06 | 10.14%            |  |  |  | No            |                  1 | On Loan: No      |
| ENCOMPASS HEALTH CORP                      | ENCOMPASS HEALTH CORP                              | CUSIP: 29261A100<br>LEI: 549300FVRPM9DRQZRG64 | Long             | EC               | CORP              | US        |    151360 | NS      | $14641052.80   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| ENDEAVOR BIO SERIES B CVT PFD STOCK PP     | END EAVOR BIO SERIES B CVT PFD STOCK PP            | CUSIP: TC0KH48I6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1867734 | NS      | $12186217.26   | 0.11%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ENDEAVOR BIO SER C CVT PFD PP              | ENDEAVOR BIO SER C CVT PFD PP                      | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    489761 | NS      | $3195494.62    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ENLIVEN THERAPEUTICS INC                   | ENLIVEN THERAPEUTICS INC                           | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     53863 | NS      | $2111429.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ENTRADA THERAPEUTICS INC                   | ENTRADA THERAPEUTICS INC                           | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    329233 | NS      | $4154920.46    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| ERASCA INC                                 | ERASCA INC                                         | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1247913 | NS      | $20191232.34   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| EVOMMUNE INC                               | EVOMMUNE INC                                       | CUSIP: 30054Y107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    246092 | NS      | $5657655.08    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| EVOMMUNE INC PIPE PP                       | EVOMMUNE INC PIPE PP                               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    125397 | NS      | $2738733.18    | 0.03%             |  |  |  | Yes           |                  2 | On Loan: No      |
| EXACT SCIENCES FDA MILESTONE PP            | EXACT SCIENCES FDA MILESTONE PP                    | CUSIP: 000000000<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |   1863136 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Eikon Therapeutics, Inc Lockup Shs PP      | Eikon Therapeutics, Inc. IPO lockup                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | RF                | US        |    371442 | NS      | $3929856.36    | 0.04%             |  |  |  | Yes           |                  2 | On Loan: No      |
| PARABILIS MED INC SER D CVT PFD STOCK PP   | FOG PHARMA SER D CVT PFD STOCK PP                  | CUSIP: TC2VY7UZ1<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    615203 | NS      | $4470987.80    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PARABILIS MED INC SER E CVT PFD STOCK PP   | FOG PHARMA SER E CVT PFD PP                        | CUSIP: TC0O5RRO6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    623217 | NS      | $3841758.87    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PARABILIS MED INC SER C CVT PFD STOCK PP   | FOG PHARMACEUTICALS SERIES C CVT PFD STOCK PP      | CUSIP: TC4W1BVL4<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    431391 | NS      | $3624245.21    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| FREENOME HOLDINGS SER B CVT PFD PP         | FREENOME HOLDINGS SER B CVT PFD PP                 | CUSIP: 000000000<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |   1558570 | NS      | $4550161.11    | 0.04%             |  |  |  | Yes           |                  2 | On Loan: No      |
| FREENOME HOLDINGS SER C CVT PFD PP         | FREENOME HOLDINGS SER C CVT PFD PP                 | CUSIP: TC87S2BF1<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |    928231 | NS      | $2709920.37    | 0.02%             |  |  |  | Yes           |                  2 | On Loan: No      |
| FREENOME HOLDINGS SER D CVT PFD PP         | FREENOME HOLDINGS SER D CVT PFD PP                 | CUSIP: 000000000<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |    526504 | NS      | $1537100.05    | 0.01%             |  |  |  | Yes           |                  2 | On Loan: No      |
| FREENOME HOLDINGS SER F CVT PFD PP         | FREENOME HOLDINGS SER F CVT PFD PP                 | CUSIP: TC17ZDYA2<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EP               | CORP              | US        |    178707 | NS      | $521725.45     | 0.00%             |  |  |  | Yes           |                  2 | On Loan: No      |
| Galvanize Therapeutics Ser C CVT PFD PP    | GALVANIZE THERAPEUTICS SER C CVT PFD PP            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |  13270470 | NS      | $5440892.70    | 0.05%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GENEDX HOLDINGS CORP WTS 7/26              | GENEDX HOLDINGS CORP                               | CUSIP: 81663L119<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    206747 | NS      | $1653.98       | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| GENERATE BIOMEDICINES INC                  | GENERATE BIOMEDICINES INC                          | CUSIP: 370920100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    265641 | NS      | $3320512.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| GENERATION BIO CO                          | GENERATION BIO CO                                  | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    102601 | NS      | $0.00          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Genesis Molecular AI Ser A CVT PFD PP      | GENESIS THERA SER A CVT PFD STOCK PP               | CUSIP: TC08XH789<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    829412 | NS      | $4236304.73    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Genesis Molecular AI Ser B CVT PFD PP      | GENESIS THERA SEV B CVT PFD STOCK PP               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1987585 | NS      | $10151789.15   | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GILEAD SCIENCES INC                        | GILEAD SCIENCES INC                                | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |   2034836 | NS      | $283595093.32  | 2.60%             |  |  |  | No            |                  1 | On Loan: No      |
| GINKGO BIOWORKS HOLDINGS INC               | GINKGO BIOWORKS HOLDINGS INC                       | CUSIP: 37611X209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     23550 | NS      | $144361.50     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| GUARDANT HEALTH INC                        | GUARDANT HEALTH INC                                | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |   1055988 | NS      | $97541611.56   | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| GYROSCOPE THERAPEUTICS MLSTNE PYMT 1 PP    | GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 1 PP      | CUSIP: 000000000<br>LEI: 21380066POJ2YSHZAD73 | Long             | EC               | CORP              | US        |   5683928 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GYROSCOPE THERAPEUTICS MLSTNE PYMT 2 PP    | GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 2 PP      | CUSIP: 000000000<br>LEI: 21380066POJ2YSHZAD73 | Long             | EC               | CORP              | US        |   3788007 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GYROSCOPE THERAPEUTICS MLSTNE PYMT 3 PP    | GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 3 PP      | CUSIP: 000000000<br>LEI: 21380066POJ2YSHZAD73 | Long             | EC               | CORP              | US        |   3788007 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GALVANIZE THERA SER C-1 CVT PFD PP         | Galvanize Therapeutics Series C-1 CVT PFD          | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   7721685 | NS      | $3165890.85    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GALVANIZE THERA SER C-2 NV CVT PFD PP      | Galvanize Therapeutics Series C-2 CVT PFD          | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |  26100000 | NS      | $10701000.00   | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Generate Biomedicines Inc Lockup Shs PP    | Generate Biomedicines Inc lockup                   | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1472673 | NS      | $18408412.50   | 0.17%             |  |  |  | Yes           |                  2 | On Loan: No      |
| GINKGO BIOWORKS HLDS ERN OUT SHS 600 PP    | Ginkgo Bioworks Holdings Earn Out Shares $15.00 PP | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5317 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GINKGO BIOWORKS HLDS ERN OUT SHS 700 PP    | Ginkgo Bioworks Holdings Earn Out Shares $17.50 PP | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5317 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| GINKGO BIOWORKS HLDS ERN OUT SH 800 PP     | Ginkgo Bioworks Holdings Earn Out Shares $20.00 PP | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      5317 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| HCA HEALTHCARE INC                         | HCA HEALTHCARE INC                                 | CUSIP: 40412C101<br>LEI: 529900PH4ZGUH2MNEU89 | Long             | EC               | CORP              | US        |    206215 | NS      | $97589186.60   | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| HIMS & HERS HEALTH INC                     | HIMS & HERS HEALTH INC                             | CUSIP: 433000106<br>LEI: 254900V041EIVTSB6D58 | Long             | EC               | CORP              | US        |     97648 | NS      | $2027172.48    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| HONOR TECHNOLOGY SER D CVT PFD PP          | HONOR TECHNOLOGY SER D CVT PFD PP                  | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   3130941 | NS      | $939282.30     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| HONOR TECHNOLOGY SER E CVT PFD STOCK PP    | HONOR TECHNOLOGY SER E CVT PFD STOCK PP            | CUSIP: TC2V4FT13<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   2095807 | NS      | $628742.10     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| IDEAYA BIOSCIENCES INC                     | IDEAYA BIOSCIENCES INC                             | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |    259143 | NS      | $8634644.76    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEXX LABORATORIES INC                     | IDEXX LABORATORIES INC                             | CUSIP: 45168D104<br>LEI: OGMTXK0LUU1HKV2P0J84 | Long             | EC               | CORP              | US        |     42552 | NS      | $23909543.28   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMATICS NV                                | IMMATICS NV                                        | CUSIP: N44445109<br>LEI: 984500DC691EZ96AF394 | Long             | EC               | CORP              | NL        |    495393 | NS      | $4874667.12    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMIX BIOPHARMA INC                        | IMMIX BIOPHARMA INC                                | CUSIP: 45258H106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    326401 | NS      | $2973513.11    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMUNEERING CORP - CLASS A                 | IMMUNEERING CORP                                   | CUSIP: 45254E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    624026 | NS      | $3288617.02    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMUNOCORE HOLDINGS CB 2.50% 2/30          | IMMUNOCORE HOLDINGS PLC                            | CUSIP: 45258DAB1<br>LEI: 213800IUE3DFS84BVN18 | Long             | DBT              | CORP              | GB        |  15469000 | PA      | $13946073.64   | 0.13%             | 2030-02-01      | Fixed         | 2.50%                 | No            |                  2 | On Loan: No      |
| IMMUNOCORE HOLDINGS PLC-ADR                | IMMUNOCORE HOLDINGS PLC                            | CUSIP: 45258D105<br>LEI: 213800IUE3DFS84BVN18 | Long             | EC               | CORP              | GB        |    643368 | NS      | $19397545.20   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMUNOME INC                               | IMMUNOME INC                                       | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1665614 | NS      | $36426978.18   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| IMMUNOVANT INC                             | IMMUNOVANT INC                                     | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     81427 | NS      | $2022646.68    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| INCYTE CORP                                | INCYTE CORP                                        | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |    460840 | NS      | $43374260.80   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| INSITRO SER B CVT PFD PP                   | INSITRO SER B CVT PFD PP                           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    883580 | NS      | $16161650.14   | 0.15%             |  |  |  | Yes           |                  3 | On Loan: No      |
| INSITRO SER C CVT PFD PP                   | INSITRO SER C CVT PFD PP                           | CUSIP: TC3HHHWL7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    588382 | NS      | $10762154.00   | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| INSMED INC                                 | INSMED INC                                         | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    702695 | NS      | $114904686.40  | 1.05%             |  |  |  | No            |                  1 | On Loan: No      |
| INSPIRE MEDICAL SYSTEMS INC                | INSPIRE MEDICAL SYSTEMS INC                        | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |    116160 | NS      | $5991532.80    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| INTUITIVE SURGICAL INC                     | INTUITIVE SURGICAL INC                             | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |    863221 | NS      | $397936248.79  | 3.65%             |  |  |  | No            |                  1 | On Loan: No      |
| IONIS PHARMACEUTICALS INC                  | IONIS PHARMACEUTICALS INC                          | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |    882823 | NS      | $66291179.07   | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| IOVANCE BIOTHERAPEUTICS INC                | IOVANCE BIOTHERAPEUTICS INC                        | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |   2047047 | NS      | $7185134.97    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA HOLDINGS INC                         | IQVIA HOLDINGS INC                                 | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |    207553 | NS      | $35396088.62   | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| JANUX THERAPEUTICS INC                     | JANUX THERAPEUTICS INC                             | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22599 | NS      | $314126.10     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| JOHNSON & JOHNSON                          | JOHNSON & JOHNSON                                  | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |   1088355 | NS      | $266037496.20  | 2.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Kailera Therapeutics SER B CVT PFD PP      | KAILERA THERAPEUTICS SER B CVT PFD PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    626703 | NS      | $8773842.00    | 0.08%             |  |  |  | Yes           |                  3 | On Loan: No      |
| KARDIUM INC SER D-5 CVT PFD STOCK PP       | KARDIUM INC SER D-5 CVT PFD STOCK PP               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   8849057 | NS      | $7249147.49    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Kardium Inc Series D-8 CVT PFD Stock PP    | KARDIUM INC SERIES D-8 CVT PFD STOCK PP            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | CA        |   6786958 | NS      | $4392790.70    | 0.04%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Kardium Inc Ser D-6 CVT Pfd Stock PP       | KARDIUM SERIES D6 CVT PFD STOCK PP                 | CUSIP: TC0GUUWU8<br>LEI: N/A                  | Long             | EP               | CORP              | US        |  12320393 | NS      | $10193893.17   | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Kartos Therapeutics CVT Prom Note PP       | KARTOS THERAPEUTICS CVT PROM NOTE PP               | CUSIP: TC9IB1JR2<br>LEI: N/A                  | Long             | DBT              | CORP              | US        |    741016 | PA      | $741016.19     | 0.01%             | 2027-03-04      | None          | 0.00%                 | Yes           |                  3 | On Loan: No      |
| KARTOS THERAPEUTICS SR C CVT PFD STK PP    | KARTOS THERAPEUTICS SR C CVT PFD STK PP            | CUSIP: TC1HQTAC7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1873841 | NS      | $10592823.17   | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Kartos Therapeutics SR D CVT PFD STK PP    | KARTOS THERAPEUTICS SR D CVT PFD STK PP            | CUSIP: TC82Z0AE2<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    513724 | NS      | $2904081.77    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| KESTRA MEDICAL TECHNOLOGIES                | KESTRA MEDICAL TECHNOLOGIES LTD                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | BM        |    744410 | NS      | $14836091.30   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| KODIAK SCIENCES INC                        | KODIAK SCIENCES INC                                | CUSIP: 50015M109<br>LEI: 254900IXI5NI8C9OQE24 | Long             | EC               | CORP              | US        |    921511 | NS      | $35127999.32   | 0.32%             |  |  |  | No            |                  1 | On Loan: No      |
| KRYSTAL BIOTECH INC                        | KRYSTAL BIOTECH INC                                | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |    273451 | NS      | $70637862.32   | 0.65%             |  |  |  | No            |                  1 | On Loan: No      |
| KYMERA THERAPEUTICS INC                    | KYMERA THERAPEUTICS INC                            | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1002367 | NS      | $83487147.43   | 0.77%             |  |  |  | No            |                  1 | On Loan: No      |
| KYVERNA THERAPEUTICS INC                   | KYVERNA THERAPEUTICS INC                           | CUSIP: 501976104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1142161 | NS      | $9856849.43    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Kardium Inc Series D-7 CVT PFD Stock PP    | Kardium, Inc. Series D-7 CVT Pfd Stock             | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |  12050573 | NS      | $7799612.87    | 0.07%             |  |  |  | Yes           |                  3 | On Loan: No      |
| LANTHEUS HOLDINGS INC                      | LANTHEUS HOLDINGS INC                              | CUSIP: 516544103<br>LEI: 5299005HUB5IOJGO7S39 | Long             | EC               | CORP              | US        |    122170 | NS      | $9266594.50    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| SAIL BIOMEDICINES SER B CVT PFD STOCK PP   | LARONDE SERIES B CVT PFD STOCK PP                  | CUSIP: TC14DLDG5<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1169887 | NS      | $1684637.28    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| LENZ THERAPEUTICS INC                      | LENZ THERAPEUTICS INC                              | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    144751 | NS      | $1324471.65    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| LIQUIDIA CORP                              | LIQUIDIA CORP                                      | CUSIP: 53635D202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    260626 | NS      | $9836025.24    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| LUMICKS TECH SER D CVT PFD STOCK PP        | LUMICKS TECH SER D CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      4954 | NS      | $2670106.92    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| MADRIGAL PHARMACEUTICALS INC               | MADRIGAL PHARMACEUTICALS INC                       | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |     74723 | NS      | $39115248.81   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| MBX BIOSCIENCES INC                        | MBX BIOSCIENCES INC                                | CUSIP: 55287L101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    721309 | NS      | $21531073.65   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| MCKESSON CORP                              | MCKESSON CORP                                      | CUSIP: 58155Q103<br>LEI: 549300WZWOM80UCFSF54 | Long             | EC               | CORP              | US        |     24522 | NS      | $21220357.92   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| MEDIWOUND LTD                              | MEDIWOUND LTD                                      | CUSIP: 000000000<br>LEI: 549300LJKCS74GRYKF90 | Long             | EC               | CORP              | IL        |     62181 | NS      | $1001735.91    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MEDPACE HOLDINGS INC                       | MEDPACE HOLDINGS INC                               | CUSIP: 58506Q109<br>LEI: 549300H8TYEUVTW14A54 | Long             | EC               | CORP              | US        |     22932 | NS      | $11011717.08   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| MERCK & CO. INC.                           | MERCK & CO INC                                     | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |   3116392 | NS      | $374870793.68  | 3.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharma 6 month Lockup Shs PP         | MIRUM PHARMA 6 MONTH LOCKUP SHS PP                 | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |    112393 | NS      | $9863722.07    | 0.09%             |  |  |  | Yes           |                  2 | On Loan: No      |
| Mirum Pharma 9 month Lockup Shs PP         | MIRUM PHARMA 9 MONTH LOCKUP SHS PP                 | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |    112393 | NS      | $9863722.07    | 0.09%             |  |  |  | Yes           |                  2 | On Loan: No      |
| MIRUM PHARMACEUTICALS INC                  | MIRUM PHARMACEUTICALS INC                          | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |    224930 | NS      | $20779033.40   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| MODERNA THERAPEUTICS INC                   | MODERNA INC                                        | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |    527555 | NS      | $26799794.00   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| MOLINA HEALTHCARE INC                      | MOLINA HEALTHCARE INC                              | CUSIP: 60855R100<br>LEI: 549300NQQCEQ46YHZ591 | Long             | EC               | CORP              | US        |     85655 | NS      | $11417811.50   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| MONOPAR THERAPEUTICS INC                   | MONOPAR THERAPEUTICS INC                           | CUSIP: 61023L207<br>LEI: 549300QJFAI7L6YHKG83 | Long             | EC               | CORP              | US        |     34428 | NS      | $1886310.12    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| MONTE ROSA THERAPEUTICS INC                | MONTE ROSA THERAPEUTICS INC                        | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1869110 | NS      | $30746859.50   | 0.28%             |  |  |  | No            |                  1 | On Loan: No      |
| MOONLAKE IMMUNOTHERAPEUTICS                | MOONLAKE IMMUNOTHERAPEUTICS                        | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |    887029 | NS      | $16534220.56   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| MANUS BIO INC SERIES ONE-6 CVT PFD PP      | Manus Bio, Inc Series One-6                        | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1223104 | NS      | $3669312.00    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Mirum Pharma Escrow Expense Fund PP        | Mirum Pharma Escrow Expense Fund PP                | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |     48097 | NS      | $45692.23      | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Mirum Pharma Escrow Indemnity PP           | Mirum Pharma Escrow Indemnity PP                   | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |   1192808 | NS      | $1133167.42    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Mirum Pharma Escrow Working Capital PP     | Mirum Pharma Escrow Working Capital PP             | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |     48097 | NS      | $45692.23      | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Mirum Pharma Indemnity Holdback Shs PP     | Mirum Pharma Indemnity Holdback Shs PP             | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |     25126 | NS      | $2205082.89    | 0.02%             |  |  |  | Yes           |                  2 | On Loan: No      |
| Mirum Pharma Milestone $500 mil PP         | Mirum Pharma Milestone $500 mil PP                 | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |   3428195 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Mirum Pharma Milestone $750 mil PP         | Mirum Pharma Milestone $750 mil PP                 | CUSIP: 000000000<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |   5713658 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| NATERA INC                                 | NATERA INC                                         | CUSIP: 632307104<br>LEI: 529900CQ3OZ0A0VYVU59 | Long             | EC               | CORP              | US        |    561746 | NS      | $112343582.54  | 1.03%             |  |  |  | No            |                  1 | On Loan: No      |
| NATIONAL RESILIENCE SR B CVT PFD STK PP    | NATIONAL RESILIENCE SER B CVT PFD STOCK            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1204832 | NS      | $26349675.84   | 0.24%             |  |  |  | Yes           |                  3 | On Loan: No      |
| NATIONAL RESILIENCE SR C CVT PFD STK PP    | NATIONAL RESILIENCE SER C CVT PFD STOCK            | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    426855 | NS      | $9335318.85    | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| NOVO-NORDISK A/S-SPONS ADR                 | NOVO NORDISK A/S                                   | CUSIP: 670100205<br>LEI: 549300DAQ1CVT6CXN342 | Long             | EC               | CORP              | DK        |    446869 | NS      | $16422435.75   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| NURIX THERAPEUTICS INC                     | NURIX THERAPEUTICS INC                             | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1215025 | NS      | $18832887.50   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| NUTCRACKER THERA SER C CVT PFD STOCK PP    | NUTCRACKER THERA SER C CVT PFD STOCK PP            | CUSIP: TC3WVBUQ2<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1027785 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| NUVALENT INC-A                             | NUVALENT INC                                       | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    459791 | NS      | $47105587.95   | 0.43%             |  |  |  | No            |                  1 | On Loan: No      |
| NUVATION BIO INC                           | NUVATION BIO INC                                   | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    186516 | NS      | $800153.64     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| OBSIDIAN THERAPEUTIC SR C CVT PFD STK PP   | OBSIDIAN THERAPEUTICS SR C CVT PFD STK PP          | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   4647794 | NS      | $8821048.23    | 0.08%             |  |  |  | Yes           |                  3 | On Loan: No      |
| OCULAR THERAPEUTIX INC                     | OCULAR THERAPEUTIX INC                             | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |   1439766 | NS      | $12194818.02   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Odyssey Therapeutics SER D CVT Pfd Stk PP  | ODYSSEY THERAPEUTICS SER D CVT PFD STK PP          | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    444487 | NS      | $668939.60     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ODYSSEY THERAPEUTICS SR B CVT PFD STK PP   | ODYSSEY THERAPEUTICS SR B CVT PFD STK PP           | CUSIP: TC4CBMMO7<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1115915 | NS      | $1763145.70    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ODYSSEY THERAPEUTICS SR C CVT PFD STK PP   | ODYSSEY THERAPEUTICS SR C CVT PFD STK PP           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    105905 | NS      | $159383.85     | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Odyssey Therapeutics Warrants 6/32 WRT PP  | ODYSSEY THERAPEUTICS WARRANTS 6/32 WRT PP          | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    133346 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| OLEMA PHARMACEUTICALS INC                  | OLEMA PHARMACEUTICALS INC                          | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    649181 | NS      | $9679288.71    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC PHARMACEUTICALS INC                   | ORIC PHARMACEUTICALS INC                           | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |   1740383 | NS      | $22050652.61   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| ORUKA THERAPEUTICS INC                     | ORUKA THERAPEUTICS INC                             | CUSIP: 687604108<br>LEI: 529900TG7O4ESUDMGI54 | Long             | EC               | CORP              | US        |    476018 | NS      | $23348682.90   | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| PALVELLA THERAPEUTICS INC                  | PALVELLA THERAPEUTICS INC                          | CUSIP: 697947109<br>LEI: 254900AJDH8PAOOI5T33 | Long             | EC               | CORP              | US        |    153120 | NS      | $19086408.00   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| PARABILIS MED INC SER F CVT PFD PP         | PARABILIS MED INC SER F CVT PFD PP                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    993688 | NS      | $6125490.31    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PAX LABS CLASS A COMMON PP                 | PAX LABS CLASS A COMMON PP                         | CUSIP: 000000000<br>LEI: 549300FKJA0AEKUHVG68 | Long             | EC               | CORP              | US        |   8397988 | NS      | $2603376.28    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PHARVARIS NV                               | PHARVARIS NV                                       | CUSIP: 000000000<br>LEI: 9845003BE146D3B75D32 | Long             | EC               | CORP              | NL        |    331529 | NS      | $9365694.25    | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| PRAXIS PRECISION MEDICINES I               | PRAXIS PRECISION MEDICINES INC                     | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    189301 | NS      | $60990889.19   | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BIOROBOTICS CORP                   | PROCEPT BIOROBOTICS CORP                           | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    289633 | NS      | $7243721.33    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| PROFOUNDBIO ESCROW FUND PAYMENT PP         | PROFOUNBIO ESCROW FUND PAYMENT                     | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    704486 | NS      | $669261.67     | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PROFOUNDBIO EXPENSE FUND PAYMENT PP        | PROFOUNDBIO EXPENSE FUND PYMT                      | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |      2348 | NS      | $469.66        | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PROGNOMIQ INC CL A Common  PP              | PROGNOMIQ INC PP                                   | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    606647 | NS      | $90997.05      | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| PROTAGONIST THERAPEUTICS INC               | PROTAGONIST THERAPEUTICS INC                       | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1142059 | NS      | $120373018.60  | 1.11%             |  |  |  | No            |                  1 | On Loan: No      |
| RADNET INC                                 | RADNET INC                                         | CUSIP: 750491102<br>LEI: 529900RECG94V2IZJ970 | Long             | EC               | CORP              | US        |     18038 | NS      | $1008143.82    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| RAPPORT THERAPEUTICS INC                   | RAPPORT THERAPEUTICS INC                           | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    601105 | NS      | $18808575.45   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Reflexion Med CVT Note issued 082725 PP    | REFLEXION MED CVT NOTE ISSUED 082725 PP            | CUSIP: 000000000<br>LEI: N/A                  | Long             | DBT              | CORP              | US        |    239698 | PA      | $647184.57     | 0.01%             | 2026-07-11      | Fixed         | 15.00%                | Yes           |                  3 | On Loan: No      |
| Reflexion Med CVT Note issued 081325 PP    | REFLEXION MED CVT PROM NOTE 081325 PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | DBT              | CORP              | US        |    239698 | PA      | $651978.53     | 0.01%             | 2026-07-11      | Fixed         | 15.00%                | Yes           |                  3 | On Loan: No      |
| Reflexion Med CVT Note issued 072525 PP    | REFLEXION MEDICAL CVT PROM NOTE PP                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | DBT              | CORP              | US        |    239698 | PA      | $656772.49     | 0.01%             | 2026-08-11      | None          | 0.00%                 | Yes           |                  3 | On Loan: No      |
| REFLEXION MEDICAL INC CVT PFD SR D-X PP    | REFLEXION MEDICAL INC CVT                          | CUSIP: TC70GKL85<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1123437 | NS      | $1460.47       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| REFLEXION MEDICAL INC CVT PFD SR C-X PP    | REFLEXION MEDICAL INC CVT PFD SR C PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   2507885 | NS      | $3260.25       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| REFLEXION MEDICAL SER F CVT PFD STOCK PP   | REFLEXION MEDICAL INC PP                           | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1794104 | NS      | $1794.10       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| REFLEXION MEDICAL INC CVT PFD SR E-X PP    | REFLEXION MEDICAL INC SR E CVT PFD PP              | CUSIP: TC9L8ZXJ6<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1857286 | NS      | $2600.20       | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| REGENERON PHARMACEUTICALS                  | REGENERON PHARMACEUTICALS INC                      | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |    373226 | NS      | $288369336.64  | 2.65%             |  |  |  | No            |                  1 | On Loan: No      |
| RELAY THERAPEUTICS INC                     | RELAY THERAPEUTICS INC                             | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1299962 | NS      | $12934621.90   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| REPLIGEN CORP                              | REPLIGEN CORP                                      | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |    108730 | NS      | $12810568.60   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| REPLIMUNE GROUP INC                        | REPLIMUNE GROUP INC                                | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |   1427764 | NS      | $10922394.60   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION MEDICINES INC WTS 12/26         | REVOLUTION MEDICINES INC                           | CUSIP: 76155X118<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |    198505 | NS      | $345398.70     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION MEDICINES INC                   | REVOLUTION MEDICINES INC                           | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |   1519722 | NS      | $147792964.50  | 1.36%             |  |  |  | No            |                  1 | On Loan: No      |
| REVVITY INC                                | REVVITY INC                                        | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |    274277 | NS      | $24029407.97   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| RHYTHM PHARMACEUTICALS INC                 | RHYTHM PHARMACEUTICALS INC                         | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |    241658 | NS      | $21016996.26   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| RING THERAPEUTICS INC PP                   | RING THERAPEUTICS INC PP                           | CUSIP: TC4CR9CB8<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    291704 | NS      | $1341838.40    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| ROCKET PHARMACEUTICALS INC                 | ROCKET PHARMACEUTICALS INC                         | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |    464628 | NS      | $1663368.24    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ROIVANT SCIENCES LTD                       | ROIVANT SCIENCES LTD                               | CUSIP: 000000000<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | BM        |   4447673 | NS      | $123200542.10  | 1.13%             |  |  |  | No            |                  1 | On Loan: No      |
| ROYALTY PHARMA PLC- CL A                   | ROYALTY PHARMA PLC                                 | CUSIP: 000000000<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |   1241743 | NS      | $59566411.71   | 0.55%             |  |  |  | No            |                  1 | On Loan: No      |
| SALUDA MEDICAL INC                         | SALUDA MEDICAL INC                                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   3958452 | NS      | $2275356.50    | 0.02%             |  |  |  | No            |                  2 | On Loan: No      |
| Saluda Medical Inc Lockup Shs CDI PP       | SALUDA MEDICAL INC PP restricted cdi               | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | AU        |   3715230 | NS      | $2101924.81    | 0.02%             |  |  |  | Yes           |                  2 | On Loan: No      |
| Saluda Med Common WTS 3/26 PP              | SALUDA MEDICAL WTS COMMON STOCK                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |         2 | NS      | $0.00          | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| SARTORIUS AG-VORZUG PREF                   | SARTORIUS AG                                       | CUSIP: 000000000<br>LEI: 529900EQV2DY4FOAMU38 | Long             | EP               | CORP              | DE        |     44309 | NS      | $11086852.90   | 0.10%             |  |  |  | No            |                  2 | On Loan: No      |
| SCHOLAR ROCK HOLDING CORP                  | SCHOLAR ROCK HOLDING CORP                          | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |   1369780 | NS      | $67338384.80   | 0.62%             |  |  |  | No            |                  1 | On Loan: No      |
| SCRIBE THERA SER B CVT PFD STOCK PP        | SCRIBE THERA SER B CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   1027755 | NS      | $6219253.83    | 0.06%             |  |  |  | Yes           |                  3 | On Loan: No      |
| SEAPORT THERAPEUTICS SER B CVT PFD PP      | SEAPORT THERAPEUTICS SER B CVT PFD PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   2322209 | NS      | $11030492.75   | 0.10%             |  |  |  | Yes           |                  3 | On Loan: No      |
| SENSORION SA                               | SENSORION SA                                       | CUSIP: 000000000<br>LEI: 969500P0W8XJ9CGZDP97 | Long             | EC               | CORP              | FR        |  16950906 | NS      | $8048741.91    | 0.07%             |  |  |  | No            |                  2 | On Loan: No      |
| SHATTUCK LABS INC                          | SHATTUCK LABS INC                                  | CUSIP: 82024L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1366288 | NS      | $8785231.84    | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| SIONNA THERAPEUTICS INC                    | SIONNA THERAPEUTICS INC                            | CUSIP: 829401108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    547443 | NS      | $21946989.87   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| SOMALOGIC INC WTS 8/26                     | SOMALOGIC INC                                      | CUSIP: 83444K113<br>LEI: 549300D3W3Q8CN30YO25 | Long             | EC               | CORP              | US        |     90179 | NS      | $0.00          | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| SONOVA HOLDING AG-REG                      | SONOVA HOLDING AG                                  | CUSIP: 000000000<br>LEI: 5299004A0QNX7FBNHS61 | Long             | EC               | CORP              | CH        |    105533 | NS      | $24062943.47   | 0.22%             |  |  |  | No            |                  2 | On Loan: No      |
| SPAC PCSC Freenome PIPE COMMIT PP          | SPAC PCSC FREENOME PIPE COMMIT PP                  | CUSIP: 000000000<br>LEI: 254900QDTSQ6S0QOCS43 | Long             | EC               | CORP              | US        |    438178 | NS      | $4326131.39    | 0.04%             |  |  |  | Yes           |                  2 | On Loan: No      |
| SPYGLASS PHARMA INC                        | SPYGLASS PHARMA INC                                | CUSIP: 85220G109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    290792 | NS      | $7534420.72    | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc                     | SPYRE THERAPEUTICS INC                             | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |    854145 | NS      | $43083073.80   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| STOKE THERAPEUTICS INC                     | STOKE THERAPEUTICS INC                             | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |    452134 | NS      | $14721483.04   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| STRUCTURE THERAPEUTICS INC ADR             | STRUCTURE THERAPEUTICS INC                         | CUSIP: 86366E106<br>LEI: N/A                  | Long             | EC               | CORP              | KY        |   1273207 | NS      | $61368577.40   | 0.56%             |  |  |  | No            |                  1 | On Loan: No      |
| STRYKER CORP                               | STRYKER CORP                                       | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |   1147522 | NS      | $377064253.98  | 3.46%             |  |  |  | No            |                  1 | On Loan: No      |
| SUMMIT THERAPEUTICS INC                    | SUMMIT THERAPEUTICS INC                            | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   5948323 | NS      | $112780204.08  | 1.04%             |  |  |  | No            |                  1 | On Loan: No      |
| T. Rowe Price Government Reserve Fund      | T. Rowe Price Government Reserve Fund              | CUSIP: 76105Y109<br>LEI: 5493002Y0IYARJVQ5N24 | Long             | STIV             | RF                | US        |  37972742 | NS      | $37972742.46   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| TANGO THERAPEUTICS INC                     | TANGO THERAPEUTICS INC                             | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    638486 | NS      | $13357127.12   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| TARSUS PHARMACEUTICALS INC                 | TARSUS PHARMACEUTICALS INC                         | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    175856 | NS      | $12336298.40   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| TECTONIC THERAPEUTIC INC                   | TECTONIC THERAPEUTIC INC                           | CUSIP: 878972108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    122254 | NS      | $3778871.14    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| TENAX THERAPEUTICS INC                     | TENAX THERAPEUTICS INC                             | CUSIP: 88032L605<br>LEI: 549300J03O6B1IJ2B606 | Long             | EC               | CORP              | US        |   2481066 | NS      | $39672245.34   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| TENET HEALTHCARE CORP                      | TENET HEALTHCARE CORP                              | CUSIP: 88033G407<br>LEI: 0W9AIBT6U6ADJ2I8HK17 | Long             | EC               | CORP              | US        |    580102 | NS      | $109471048.42  | 1.00%             |  |  |  | No            |                  1 | On Loan: No      |
| TERNS PHARMACEUTICALS INC                  | TERNS PHARMACEUTICALS INC                          | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |    557042 | NS      | $29367254.24   | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| TESSERA THERAPEUTICS SER D CVT PFD PP      | TESSERA THERAPEUTICS SER D CVT PFD PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    381989 | NS      | $1978703.02    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| THERMO FISHER SCIENTIFIC INC               | THERMO FISHER SCIENTIFIC INC                       | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |    900979 | NS      | $442858207.87  | 4.07%             |  |  |  | No            |                  1 | On Loan: No      |
| THIRD ARC BIO SER A CVT PFD PP             | THIRD ARC BIO SER A CVT PFD PP                     | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   4810936 | NS      | $10123171.53   | 0.09%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Treeline Bio Common WTS 8/35 PP            | TREELINE BIO COMMON WTS 8.35 PP                    | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     44917 | NS      | $327310.18     | 0.00%             |  |  |  | Yes           |                  3 | On Loan: No      |
| TREELINE BIO SER A CVT PFD STOCK PP        | TREELINE BIO SER A CVT PFD STOCK PP                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   2370150 | NS      | $17271283.05   | 0.16%             |  |  |  | Yes           |                  3 | On Loan: No      |
| TREELINE BIO SER A-1 CVT PFD STOCK PP      | TREELINE BIO SER A-1 CVT PFD STOCK PP              | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |   2744291 | NS      | $19997648.52   | 0.18%             |  |  |  | Yes           |                  3 | On Loan: No      |
| Treeline Bio SER A-2 CVT PFD PP            | TREELINE BIO SER A-2 NV CVT PFD PP                 | CUSIP: 000000000<br>LEI: N/A                  | Long             | EP               | CORP              | US        |    299448 | NS      | $2182077.58    | 0.02%             |  |  |  | Yes           |                  3 | On Loan: No      |
| TYRA BIOSCIENCES INC                       | TYRA BIOSCIENCES INC                               | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    307082 | NS      | $11761240.60   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| TESSERA THERAPEUTICS SER C' CVT PFD PP     | Tessera Therapeutics, Inc. Series C                | CUSIP: 000000000<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    674174 | NS      | $3492221.32    | 0.03%             |  |  |  | Yes           |                  3 | On Loan: No      |
| UNITED THERAPEUTICS CORP                   | UNITED THERAPEUTICS CORP                           | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |    246943 | NS      | $146432260.14  | 1.34%             |  |  |  | No            |                  1 | On Loan: No      |
| UNITEDHEALTH GROUP INC                     | UNITEDHEALTH GROUP INC                             | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |   1242865 | NS      | $336306840.35  | 3.09%             |  |  |  | No            |                  1 | On Loan: No      |
| VAXCYTE INC                                | VAXCYTE INC                                        | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |    314645 | NS      | $18284020.95   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| VERA THERAPEUTICS INC                      | VERA THERAPEUTICS INC                              | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |   1235806 | NS      | $49716475.38   | 0.46%             |  |  |  | No            |                  1 | On Loan: No      |
| VERILY LIFE SCIENCES LLC SER B UNITS PP    | VERILY LIFE SCIENCES LLC SER B UNITS PP            | CUSIP: 000000000<br>LEI: 5493003ZYK1Z7M670M44 | Long             | EC               | CORP              | US        |    113564 | NS      | $1265988.76    | 0.01%             |  |  |  | Yes           |                  3 | On Loan: No      |
| VERTEX PHARMACEUTICALS INC                 | VERTEX PHARMACEUTICALS INC                         | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |    591295 | NS      | $264036869.30  | 2.42%             |  |  |  | No            |                  1 | On Loan: No      |
| VIATRIS INC                                | VIATRIS INC                                        | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |    927240 | NS      | $12527012.40   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| VIRIDIAN THERAPEUTICS INC                  | VIRIDIAN THERAPEUTICS INC                          | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |    343846 | NS      | $6725627.76    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| WAVE LIFE SCIENCES LTD                     | WAVE LIFE SCIENCES LTD                             | CUSIP: 000000000<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | SG        |   2107233 | NS      | $15277439.25   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| WEST PHARMACEUTICAL SERVICES               | WEST PHARMACEUTICAL SERVICES INC                   | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |     97625 | NS      | $24468730.00   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| XENCOR INC                                 | XENCOR INC                                         | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |    378576 | NS      | $4565626.56    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| ZAI LAB LTD ADR                            | ZAI LAB LTD                                        | CUSIP: 98887Q104<br>LEI: 549300P2UYQ9U5LY1T58 | Long             | EC               | CORP              | KY        |    213174 | NS      | $4009802.94    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2026-05-05

**Name of Applicant:** T. ROWE PRICE HEALTH SCIENCES FUND, INC.

**Signature:** /s/ Alan Dupski

**Name of Signer:** Alan Dupski

**Title:** Treasurer & Vice President