# EDGAR Filing Document

**Accession Number:** 0001631134
**File Stem:** 0001631134-25-000006
**Filing Date:** 2025-8
**Character Count:** 31000
**Document Hash:** fa48110c7b50cb414b6dea791b13b780
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001631134-25-000006.hdr.sgml**: 20250827

**ACCESSION NUMBER**: 0001631134-25-000006

**CONFORMED SUBMISSION TYPE**: N-PX

**PUBLIC DOCUMENT COUNT**: 2

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250827

**EFFECTIVENESS DATE**: 20250827

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Sofinnova Investments, Inc.
- **CENTRAL INDEX KEY:** 0001631134

**ORGANIZATION NAME:**
- **EIN:** 000000000

**FILING VALUES:**
- **FORM TYPE:** N-PX
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 028-18774
- **FILM NUMBER:** 251266285

**BUSINESS ADDRESS:**
- **STREET 1:** 3000 Sand Hill Road
- **STREET 2:** BUILDING 3-SUITE 150
- **CITY:** Menlo Park
- **STATE:** CA
- **ZIP:** 94025
- **BUSINESS PHONE:** 650.681.8428

**MAIL ADDRESS:**
- **STREET 1:** 3000 Sand Hill Road
- **STREET 2:** BUILDING 3-SUITE 150
- **CITY:** Menlo Park
- **STATE:** CA
- **ZIP:** 94025

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Sofinnova Ventures Inc
- **DATE OF NAME CHANGE:** 20150120

## FORM N-PX
### ANNUAL REPORT OF PROXY VOTING RECORD

## N-PX: Filer Information

**Filer CIK:** 0001631134

**Date of Report:** 06/30/2025

**Are you a Registered Management Investment Company or an Institutional Manager?:** Institutional Manager

**Is this a LIVE or TEST Filing?:** LIVE

**Is this an electronic copy of an official filing submitted in paper format?:** [ ]

### Submission Contact Information
_Not provided in this filing._

### Notification Information
**Notify via Filing Website only?:** [ ]

## N-PX: Cover Page

**Name of reporting person:** Sofinnova Investments, Inc.

**Address:** 3000 Sand Hill Road, Menlo Park, CA 94025

**Telephone number:** (650) 681-8428

**Name of agent for service:** —

**Agent Address:** —, —, — —

**Reporting Period:** Report for the year ended 06/30/2025

**SEC File Number:** 028-18774

**CRD Number (if any):** —

**Other SEC File Number (if any):** —

**LEI (if any):** 549300HVTF5RFS1C0D72

**Report Type (check only one):**

Institutional Manager.

- [x] Institutional Manager Voting Report

- [ ] Institutional Manager Notice Report

- [ ] Institutional Manager Combination Report

Registered Management Investment Company.

- [ ] Fund Voting Report

- [ ] Fund Notice Report

**Do you wish to provide explanatory information pursuant to Special Instruction B.4?:**

- [x] No

- [ ] Yes

**Additional information:** —

## N-PX: Summary - Included Managers

**Number of Included Institutional Managers:** 0

**Included Institutional Managers:** —

## FORM N-PX PROXY VOTING RECORD

| NAME OF ISSUER                   | CUSIP     | MEETING DATE   | VOTE DESCRIPTION                                                                                                                                                                                                                                                                                                            | VOTE CATEGORY                |     SHARES VOTED |   SHARES ON LOAN | HOW VOTED   | SHARES VOTED FOR OR AGAINST MANAGEMENT   | FOR OR AGAINST MANAGEMENT   | OTHER INFO   |
|:---|:---|:---|:---|:---|---:|---:|:---|:---|:---|:---|
| Masimo Corporation               | 574795100 | 09/19/2024     | To provide an advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |      0           |                0 |  |  |  |  |
| Masimo Corporation               | 574795100 | 09/19/2024     | An advisory vote to approve the compensation of the Company's named executive officers.                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |   1204           |                0 | FOR         | 1204.000000                              | AGAINST                     |  |
| Becton, Dickinson and Company    | 075887109 | 01/28/2025     | Advisory vote to approve named executive officer compensation.                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |   3636           |                0 | FOR         | 3636.000000                              | FOR                         |  |
| Boston Scientific Corporation    | 101137107 | 05/01/2025     | To approve, on a non-binding, advisory basis, the compensation of our named executive officers.                                                                                                                                                                                                                             | SECTION 14A SAY-ON-PAY VOTES |  53819           |                0 | FOR         | 53819.000000                             | FOR                         |  |
| Intuitive Surgical, Inc.         | 46120E602 | 05/01/2025     | To approve, by advisory vote, the compensation of the Company's Named Executive Officers.                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |  19435           |                0 | FOR         | 19435.000000                             | FOR                         |  |
| Eli Lilly and Company            | 532457108 | 05/05/2025     | Approval, on an advisory basis, of the compensation paid to the company's named executive officers.                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |  25949           |                0 | FOR         | 25949.000000                             | FOR                         |  |
| Bristol-Myers Squibb Company     | 110122108 | 05/06/2025     | Advisory Vote to Approve the Compensation of our Named Executive Officers                                                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES | 319750           |                0 | FOR         | 319750.000000                            | FOR                         |  |
| Danaher Corporation              | 235851102 | 05/06/2025     | To approve on an advisory basis the Company's named executive officer compensation.                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |  38095           |                0 | FOR         | 38095.000000                             | FOR                         |  |
| Alnylam Pharmaceuticals, Inc.    | 02043Q107 | 05/08/2025     | To approve, in a non-binding advisory vote, the compensation of Alnylam's named executive officers.                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |  92553           |                0 | FOR         | 92553.000000                             | FOR                         |  |
| DexCom, Inc.                     | 252131107 | 05/08/2025     | To provide a non-binding advisory vote on the compensation of our named executive officers for the fiscal year ended December 31, 2024.                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES | 334540           |                0 | FOR         | 334540.000000                            | FOR                         |  |
| Stryker Corporation              | 863667101 | 05/08/2025     | Advisory Vote to Approve Named Executive Officer Compensation.                                                                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |  61643           |                0 | FOR         | 61643.000000                             | FOR                         |  |
| AbbVie Inc.                      | 00287Y109 | 05/09/2025     | Say on Pay - An advisory vote on the approval of executive compensation                                                                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES | 131904           |                0 | FOR         | 131904.000000                            | FOR                         |  |
| Syndax Pharmaceuticals, Inc.     | 87164F105 | 05/14/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the 2025 proxy statement.                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |      1.9938e+06  |                0 | FOR         | 1993799.000000                           | FOR                         |  |
| Vera Therapeutics, Inc.          | 92337R101 | 05/14/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |      1.44094e+06 |                0 | FOR         | 1440942.000000                           | FOR                         |  |
| Vera Therapeutics, Inc.          | 92337R101 | 05/14/2025     | To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's named executive officers.                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |      1.44094e+06 |                0 | ONE YEAR    | 1440942.000000                           | FOR                         |  |
| Insmed Incorporated              | 457669307 | 05/15/2025     | An advisory vote on the 2024 compensation of our named executive officers.                                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES | 107415           |                0 | FOR         | 107415.000000                            | FOR                         |  |
| SCHOLAR ROCK HOLDING CORPORATION | 80706P103 | 05/22/2025     | To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES |  15510           |                0 | FOR         | 15510.000000                             | FOR                         |  |
| Establishment Labs Holdings Inc. | G31249108 | 05/23/2025     | To approve, on an advisory basis, the compensation of our named executive officers;                                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |   5045           |                0 | FOR         | 5045.000000                              | FOR                         |  |
| Penumbra, Inc.                   | 70975L107 | 05/28/2025     | To approve, on an advisory basis, the compensation of Penumbra, Inc.'s named executive officers as disclosed in the proxy statement;                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES |  19061           |                0 | FOR         | 19061.000000                             | FOR                         |  |
| Vir Biotechnology, Inc.          | 92764N102 | 05/29/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES |  55050           |                0 | FOR         | 55050.000000                             | FOR                         |  |
| Dyne Therapeutics, Inc.          | 26818M108 | 05/30/2025     | To vote, on an advisory basis, to approve the compensation of our named executive officers.                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES | 428863           |                0 | FOR         | 428863.000000                            | FOR                         |  |
| Dyne Therapeutics, Inc.          | 26818M108 | 05/30/2025     | To hold an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES | 428863           |                0 | ONE YEAR    | 428863.000000                            | FOR                         |  |
| Akero Therapeutics, Inc.         | 00973Y108 | 06/03/2025     | To consider and act upon a non-binding, advisory vote to approve the compensation of our named executive officers.                                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES | 182989           |                0 | FOR         | 182989.000000                            | FOR                         |  |
| Cogent Biosciences, Inc.         | 19240Q201 | 06/04/2025     | Approval, on a non-binding, advisory basis, of the compensation of the Company's named executive officers.                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES |      1.43177e+06 |                0 | FOR         | 1431770.000000                           | FOR                         |  |
| Kura Oncology, Inc.              | 50127T109 | 06/05/2025     | Approval, on an advisory basis, of the compensation of our named executive officers, as disclosed in the proxy statement.                                                                                                                                                                                                   | SECTION 14A SAY-ON-PAY VOTES | 498846           |                0 | FOR         | 498846.000000                            | FOR                         |  |
| Sarepta Therapeutics, Inc.       | 803607100 | 06/05/2025     | ADVISORY VOTE TO APPROVE, ON A NON-BINDING BASIS, NAMED EXECUTIVE OFFICER COMPENSATION                                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES | 183041           |                0 | FOR         | 183041.000000                            | FOR                         |  |
| Savara Inc.                      | 805111101 | 06/05/2025     | To approve, on an advisory basis, the compensation of our named executives.                                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |      2.86719e+06 |                0 | FOR         | 2867188.000000                           | FOR                         |  |
| Savara Inc.                      | 805111101 | 06/05/2025     | To indicate, on an advisory basis, the preferred frequency of holding an advisory vote on the compensation of our named executives.                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES |      2.86719e+06 |                0 | ONE YEAR    | 2867188.000000                           | FOR                         |  |
| Axsome Therapeutics, Inc.        | 05464T104 | 06/06/2025     | To approve, by non-binding advisory vote, the compensation of our named executive officers.                                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |  16074           |                0 | FOR         | 16074.000000                             | FOR                         |  |
| Arcus Biosciences, Inc.          | 03969F109 | 06/10/2025     | To approve, on an advisory basis, the compensation of Arcus Biosciences' named executive officers, as disclosed in the Proxy Statement.                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES | 503101           |                0 | FOR         | 503101.000000                            | FOR                         |  |
| Avidity Biosciences, Inc.        | 05370A108 | 06/10/2025     | To consider and vote upon, on an advisory basis, the compensation of our named executive officers as disclosed in this proxy statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission; and                                                                                         | SECTION 14A SAY-ON-PAY VOTES | 106223           |                0 | AGAINST     | 106223.000000                            | AGAINST                     |  |
| Incyte Corporation               | 45337C102 | 06/10/2025     | Approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers.                                                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES | 257467           |                0 | FOR         | 257467.000000                            | FOR                         |  |
| Disc Medicine, Inc.              | 254604101 | 06/11/2025     | To approve, on a non-binding, advisory basis, the compensation paid to the Company's named executive officers.                                                                                                                                                                                                              | SECTION 14A SAY-ON-PAY VOTES |   4915           |                0 | FOR         | 4915.000000                              | FOR                         |  |
| Disc Medicine, Inc.              | 254604101 | 06/11/2025     | To recommend, by a non-binding advisory vote, the frequency of future advisory votes on the compensation paid to the Company's named executive officers.                                                                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |   4915           |                0 | ONE YEAR    | 4915.000000                              | FOR                         |  |
| uniQure N.V.                     | N90064101 | 06/11/2025     | Approval, on an advisory basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                                         | SECTION 14A SAY-ON-PAY VOTES | 444105           |                0 | FOR         | 444105.000000                            | FOR                         |  |
| Natera, Inc.                     | 632307104 | 06/12/2025     | To approve, on an advisory (non-binding) basis, the compensation of Natera, Inc.'s named executive officers as disclosed in the proxy statement.                                                                                                                                                                            | SECTION 14A SAY-ON-PAY VOTES | 375000           |                0 | FOR         | 375000.000000                            | FOR                         |  |
| Edgewise Therapeutics, Inc.      | 28036F105 | 06/13/2025     | Conduct an advisory vote on the compensation of our named executive officers.                                                                                                                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES | 520757           |                0 | FOR         | 520757.000000                            | FOR                         |  |
| Edgewise Therapeutics, Inc.      | 28036F105 | 06/13/2025     | Conduct an advisory vote on the frequency of future advisory votes on the compensation of our named executive officers.                                                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES | 520757           |                0 | ONE YEAR    | 520757.000000                            | FOR                         |  |
| Supernus Pharmaceuticals, Inc.   | 868459108 | 06/16/2025     | to approve, on a non-binding basis, the compensation paid to our named executive officers;                                                                                                                                                                                                                                  | SECTION 14A SAY-ON-PAY VOTES | 319811           |                0 | FOR         | 319811.000000                            | FOR                         |  |
| AnaptysBio, Inc.                 | 032724106 | 06/17/2025     | To conduct a non-binding advisory vote on the compensation of our named executive officers as disclosed in the accompanying materials.                                                                                                                                                                                      | SECTION 14A SAY-ON-PAY VOTES | 813516           |                0 | AGAINST     | 813516.000000                            | AGAINST                     |  |
| AnaptysBio, Inc.                 | 032724106 | 06/17/2025     | Non-binding advisory vote on the frequency of holding future advisory votes regarding named executive officer compensation.                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES | 813516           |                0 | ONE YEAR    | 813516.000000                            | FOR                         |  |
| PTC Therapeutics, Inc.           | 69366J200 | 06/17/2025     | Approval on a non-binding, advisory basis, of the Company's named executive officer compensation as described in the proxy statement.                                                                                                                                                                                       | SECTION 14A SAY-ON-PAY VOTES | 284172           |                0 | FOR         | 284172.000000                            | FOR                         |  |
| Blueprint Medicines Corporation  | 09627Y109 | 06/18/2025     | Approval of a non-binding advisory vote on the compensation paid to our named executive officers.                                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES |  44653           |                0 | FOR         | 44653.000000                             | FOR                         |  |
| BridgeBio Pharma, Inc.           | 10806X102 | 06/20/2025     | To cast a non-binding, advisory vote to approve the compensation of the Company's named executive officers.                                                                                                                                                                                                                 | SECTION 14A SAY-ON-PAY VOTES |  43151           |                0 | AGAINST     | 43151.000000                             | AGAINST                     |  |
| NextCure, Inc.                   | 65343E207 | 06/20/2025     | Approval, on an advisory basis, of the compensation paid by Company to its named executive officers.                                                                                                                                                                                                                        | SECTION 14A SAY-ON-PAY VOTES | 550000           |                0 | FOR         | 550000.000000                            | FOR                         |  |
| NextCure, Inc.                   | 65343E207 | 06/20/2025     | Approval, on an advisory basis, of whether a vote on the compensation of our named executive officers should take place every one year, every two years or every three years.                                                                                                                                               | SECTION 14A SAY-ON-PAY VOTES | 550000           |                0 | ONE YEAR    | 550000.000000                            | FOR                         |  |
| Structure Therapeutics Inc.      | 86366E106 | 06/23/2025     | To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the proxy statement.                                                                                                                                                                                          | SECTION 14A SAY-ON-PAY VOTES |   4695           |                0 | FOR         | 4695.000000                              | FOR                         |  |
| Structure Therapeutics Inc.      | 86366E106 | 06/23/2025     | To indicate, on an advisory basis, the preferred frequency of shareholder advisory votes on the compensation of the Company's named executive officers.                                                                                                                                                                     | SECTION 14A SAY-ON-PAY VOTES |   4695           |                0 | ONE YEAR    | 4695.000000                              | FOR                         |  |
| IDEAYA Biosciences, Inc.         | 45166A102 | 06/24/2025     | To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers as disclosed in the Proxy Statement accompanying this Notice of Annual Meeting of Stockholders.                                                                                                                    | SECTION 14A SAY-ON-PAY VOTES |      1.294e+06   |                0 | FOR         | 1294000.000000                           | FOR                         |  |
| Rhythm Pharmaceuticals, Inc.     | 76243J105 | 06/24/2025     | Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company.                                                                                                                                                                                                           | SECTION 14A SAY-ON-PAY VOTES | 112114           |                0 | AGAINST     | 112114.000000                            | AGAINST                     |  |
| Praxis Precision Medicines, Inc. | 74006W207 | 06/26/2025     | To approve, on an advisory (non-binding) basis, the compensation of the named executive officers as disclosed in the Company's proxy statement for the 2025 Annual Meeting of Stockholders pursuant to the applicable compensation disclosure rules of the SEC, including the compensation tables and narrative discussion. | SECTION 14A SAY-ON-PAY VOTES |   3392           |                0 | AGAINST     | 3392.000000                              | AGAINST                     |  |

## N-PX: Signature Block

**Reporting Person:** Sofinnova Investments, Inc.

**By (Signature):** Jim Brody

**By (Printed Signature):** Jim Brody

**By (Title):** CCO

**Date:** 08/27/2025