# EDGAR Filing Document

**Accession Number:** 0001787400
**File Stem:** 0001193125-26-002592
**Filing Date:** 2026-1
**Character Count:** 21060
**Document Hash:** ce823214e58f551babb7ed86be62bebe
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001193125-26-002592.hdr.sgml**: 20260105

**ACCESSION NUMBER**: 0001193125-26-002592

**CONFORMED SUBMISSION TYPE**: S-8

**PUBLIC DOCUMENT COUNT**: 14

**FILED AS OF DATE**: 20260105

**DATE AS OF CHANGE**: 20260105

**EFFECTIVENESS DATE**: 20260105

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** Nkarta, Inc.
- **CENTRAL INDEX KEY:** 0001787400
- **STANDARD INDUSTRIAL CLASSIFICATION:** PHARMACEUTICAL PREPARATIONS [2834]
- **ORGANIZATION NAME:** 03 Life Sciences
- **EIN:** 474515206
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** S-8
- **SEC ACT:** 1933 Act
- **SEC FILE NUMBER:** 333-292579
- **FILM NUMBER:** 26507183

**BUSINESS ADDRESS:**
- **STREET 1:** 1150 VETERANS BOULEVARD
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080
- **BUSINESS PHONE:** (925) 407-1049

**MAIL ADDRESS:**
- **STREET 1:** 1150 VETERANS BOULEVARD
- **CITY:** SOUTH SAN FRANCISCO
- **STATE:** CA
- **ZIP:** 94080

As filed with the Securities and Exchange Commission on January 5, 2026

Registration No.333-

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

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FORM S-8

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

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**Nkarta, Inc.**

(Exact name of registrant as specified in its charter)

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| | |
|:---|:---|
| **Delaware** | **47-4515206** |
| (State or other jurisdiction of | (I.R.S. Employer |
| incorporation or organization) | Identification No.) |

---

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**Nkarta, Inc.**

**1150 Veterans Boulevard**

**South San Francisco, CA 94080**<br>(Address, including zip code, of Principal Executive Offices)

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**Nkarta, Inc. 2020 Performance Incentive Plan**

**Nkarta, Inc. Employee Stock Purchase Plan**

(Full title of the plan)

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**Paul J. Hastings**

**Chief Executive Officer**

**Nkarta, Inc.**

**1150 Veterans Boulevard**

**South San Francisco, CA 94080**

**(925) 407-1049**

(Name, address and telephone number, including area code, of agent for service)

COPY TO:

**C. Brophy Christensen, Jr., Esq.**

**O'Melveny & Myers LLP**

**Two Embarcadero Center, 28th Floor**

**San Francisco, California 94111-3823**

**(415) 984-8700**

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Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act.

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| | |
|:---|:---|
| Large accelerated filer  | Accelerated filer  |
| Non-accelerated filer  | Smaller reporting company  |
|  | Emerging growth company  |

---

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. 

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**EXPLANATORY NOTE**

The Registrant is filing this Registration Statement for the purpose of registering additional shares of Common Stock issuable pursuant to the Registrant's 2020 Performance Incentive Plan and the Registrant's Employee Stock Purchase Plan and consists only of those items required by General Instruction E to Form S-8.

**__________________________**

**PART I**

INFORMATION REQUIRED IN THE

SECTION 10(a) PROSPECTUS

The document(s) containing the information specified in Part I of Form S-8 will be sent or given to participants as specified by Rule 428(b)(1) promulgated under the Securities Act of 1933, as amended (the "Securities Act").

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**PART II**

INFORMATION REQUIRED IN THE

REGISTRATION STATEMENT

**Item 3. Incorporation of Certain Documents by Reference**

The following documents of the Company filed with the Securities and Exchange Commission (the "Commission") are incorporated herein by reference:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) The Company's Registration Statements on Form S-8, filed with the Commission on [<u>August 3, 2020</u>](https://www.sec.gov/Archives/edgar/data/1787400/000156459020035577/nktx-s8.htm), [<u>January 15, 2021</u>](https://www.sec.gov/Archives/edgar/data/1787400/000156459021001302/nktx-s8.htm), [<u>March 17, 2022</u>](https://www.sec.gov/Archives/edgar/data/1787400/000156459022010894/nktx-s8.htm), [<u>January 9, 2023</u>](https://www.sec.gov/Archives/edgar/data/1787400/000095017023000507/nktx-s8-20230109.htm), [<u>January 3, 2024</u>](https://www.sec.gov/Archives/edgar/data/1787400/000095017024000900/nktx-s8-20240103.htm) and [<u>January 2, 2025</u>](https://www.sec.gov/Archives/edgar/data/1787400/000095017025000486/nktx-20250102.htm) (Commission File Nos. 333-240309, 333-252134, 333-263650, 333-269164, 333-276361, and 333-284111 respectively).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the Commission on [<u>March 26, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000095017025045262/nktx-20241231.htm) (Commission File No. 001-39370).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(c) The portions of the Company's Definitive Proxy Statement on Schedule 14A, filed with the Commission on [<u>April 21, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000114036125014740/ny20043443x1_def14a.htm) that are incorporated by reference in Part III of the Company's Annual Report on Form 10-K for its fiscal year ended December 31, 2024 (Commission File No. 001-39370).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(d) The Company's Quarterly Reports on Form 10-Q for the fiscal quarters ended March 31, 2025, June 30, 2025, and September 30, 2025, filed with the Commission on [<u>May 14, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000095017025071455/nktx-20250331.htm), [<u>August 12, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000119312525178964/nktx-20250630.htm), and [<u>November 10, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000119312525274304/nktx-20250930.htm), respectively (each, Commission File No. 001-39370).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(e) The Company's Current Reports on Form 8-K, filed with the Commission on [<u>March 26, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000095017025045231/nktx-20250326.htm) and [<u>June 6, 2025</u>](https://www.sec.gov/ix?doc=/Archives/edgar/data/1787400/000095017025082717/nktx-20250603.htm) (each, Commission File No. 001-39370, and in each case only as to the information "filed" with the Commission thereunder for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act") and not as to information "furnished" thereunder).

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(f) The description of the Company's Common Stock contained in its Registration Statement on Form 8-A, filed with the Commission on [<u>July 2, 2020</u>](https://www.sec.gov/Archives/edgar/data/1787400/000119312520186958/d77883d8a12b.htm) as modified by the description of the Company's Common Stock contained in Exhibit 4.3 of the Company's Annual Report on Form 10-K for the year ended December 31, 2024 (each, Commission File No. 001-39370), and any other amendment or report filed for the purpose of updating such description.

All documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing of such documents; provided, however, that documents or information deemed to have been furnished and not filed in accordance with Commission rules shall not be deemed incorporated by reference into this Registration Statement. Any statement contained herein or in a document, all or a portion of which is incorporated or deemed to be incorporated by reference herein, shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or amended, to constitute a part of this Registration Statement.

**Item 5. Interests of Named Experts and Counsel**

Not applicable.

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**Item 8. Exhibits**

The exhibits to this Registration Statement are listed below.

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**EXHIBIT INDEX**

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| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
|  |  | **Incorporated by Reference** | **Incorporated by Reference** | **Incorporated by Reference** | **Incorporated by Reference** |  |
| **Exhibit**<br>**Number** | **Description** | **Form** | **File No.** | **Exhibit** | **Filing Date** | **Filed**<br>**Herewith** |
| 4.1 | [<u>Nkarta, Inc. 2020 Performance Incentive Plan.</u>](https://www.sec.gov/Archives/edgar/data/1787400/000119312520186953/d884708dex104.htm) | S-1/A | 333-239301 | 10.4 | 7/2/2020 |  |
| 4.2 | [<u>Nkarta, Inc. Employee Stock Purchase Plan.</u>](https://www.sec.gov/Archives/edgar/data/1787400/000119312520186953/d884708dex105.htm) | S-1/A | 333-239301 | 10.5 | 7/2/2020 |  |
| 5 | [<u>Opinion of O'Melveny & Myers LLP.</u>](nktx-ex5.htm) |  |  |  |  | X |
| 23.1 | [<u>Consent of Independent Registered Public Accounting Firm.</u>](nktx-ex23_1.htm) |  |  |  |  | X |
| 23.2 | [<u>Consent of O'Melveny & Myers LLP (see Exhibit 5).</u>](nktx-ex5.htm) |  |  |  |  |  |
| 24 | [<u>Power of Attorney (included on signature page thereto).</u>](#power_attorney_1)<br>|  |  |  |  |  |
| 107 | [<u>Filing Fee Table.</u>](nktx_exfilingfees.htm) |  |  |  |  | X |

---

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**SIGNATURES**

Pursuant to the requirements of the Securities Act, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S8 and has duly caused this Form S-8 Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of South San Francisco, State of California, on January 5, 2026.

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| | |
|:---|:---|
| &nbsp;&nbsp;NKARTA, INC. | &nbsp;&nbsp;NKARTA, INC. |
| &nbsp;&nbsp;By: | &nbsp;&nbsp;/s/ Paul J. Hastings |
|  | &nbsp;&nbsp;Paul J. Hastings |
|  | &nbsp;&nbsp;Chief Executive Officer |

---

**POWER OF ATTORNEY**

Each person whose signature appears below constitutes and appoints Paul J. Hastings and Nadir Mahmood, and each of them, acting individually and without the other, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place, and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments, exhibits thereto and other documents in connection therewith) to this Registration Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or either of them individually, or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

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Pursuant to the requirements of the Securities Act, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.

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| | | |
|:---|:---|:---|
| &nbsp;&nbsp;<u>Signature</u> | &nbsp;&nbsp;<u>Title</u> | &nbsp;&nbsp;<u>Date</u> |
| &nbsp;&nbsp;/s/ Paul J. Hastings | &nbsp;&nbsp;Chief Executive Officer and Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Paul J. Hastings | &nbsp;&nbsp;(Principal Executive Officer) |  |
| &nbsp;&nbsp;/s/ Nadir Mahmood | &nbsp;&nbsp;President | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Nadir Mahmood | &nbsp;&nbsp;(Principal Financial and <br>Accounting Officer) |  |
| &nbsp;&nbsp;/s/ Ali Behbahani | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Ali Behbahani, M.D., M.B.A. |  |  |
| &nbsp;&nbsp;/s/ Michael Dybbs | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Michael Dybbs, Ph.D. |  |  |
| &nbsp;&nbsp;/s/ Simeon George | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Simeon George, M.D., M.B.A. |  |  |
| &nbsp;&nbsp;/s/ Leone Patterson | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Leone Patterson, M.B.A. |  |  |
| &nbsp;&nbsp;/s/ Zachary Scheiner | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Zachary Scheiner, Ph.D. |  |  |
| &nbsp;&nbsp;/s/ Angela Thedinga | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;Angela Thedinga, M.B.A. |  |  |
| &nbsp;&nbsp;/s/ George Vratsanos | &nbsp;&nbsp;Director | &nbsp;&nbsp;January 5, 2026 |
| &nbsp;&nbsp;George Vratsanos, M.D., F.A.C.R. |  |  |

---

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## Ex-5

**EXHIBIT 5**

[O'Melveny & Myers letterhead]

January 5, 2026

Nkarta, Inc.

1150 Veterans Boulevard

South San Francisco, CA 94080

Re: Registration of Securities of Nkarta, Inc.

Ladies and Gentlemen:

In connection with the registration by Nkarta, Inc. (the "Company") under the Securities Act of 1933, as amended, of up to (i) 3,553,926 shares (the "2020 Plan Shares") of the Company's common stock, $0.0001 par value per share (the "Common Stock") to be issued or delivered pursuant to the Nkarta, Inc. 2020 Performance Incentive Plan (the "2020 Plan") and (ii) 710,785 shares (the "ESPP Shares" and together with the 2020 Plan Shares, the "Shares") of Common Stock to be issued or delivered pursuant to the Nkarta, Inc. Employee Stock Purchase Plan (the "ESPP" and together with the 2020 Plan, the "Plans"), in each case pursuant to a Registration Statement on Form S-8 (the "Registration Statement") filed with the Securities and Exchange Commission on or about the date hereof, you have requested our opinion set forth below.

In our capacity as counsel, we have examined originals or copies of those corporate and other records of the Company we considered appropriate.

On the basis of such examination and our consideration of those questions of law we considered relevant, and subject to the limitations and qualifications in this opinion, we are of the opinion that the Shares have been duly authorized by all necessary corporate action on the part of the Company and, when issued in accordance with such authorization, the provisions of the applicable Plan and relevant agreements duly authorized by and in accordance with the terms of the applicable Plan, and upon payment for and delivery of the Shares as contemplated in accordance with the Plans, and either (a) the countersigning of the certificate or certificates representing the Shares by a duly authorized signatory of the registrar for the Company's Common Stock, or (b) the book-entry of the Shares by the transfer agent for the Company's Common Stock in the name of The Depository Trust Company or its nominee, the Shares will be validly issued, fully paid and non-assessable.

We consent to your filing this opinion as an exhibit to the Registration Statement.

Respectfully submitted,

/s/ O'Melveny & Myers LLP

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## Exhibit 23.1

**EXHIBIT 23.1**

**Consent of Independent Registered Public Accounting Firm**

We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the Nkarta, Inc. 2020 Performance Incentive Plan and Nkarta, Inc. Employee Stock Purchase Plan of our report dated March 26, 2025, with respect to the financial statements of Nkarta, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2024, filed with the Securities and Exchange Commission.

/s/ Ernst & Young LLP

San Mateo, California

January 5, 2026

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## Ex-Filing

?xml version='1.0' encoding='ASCII'? EX-FILING FEES

**EXHIBIT 107**

**Calculation of** Filing Fee Table

…………..

**<u>Form</u>** S-8

(Form Type)

………………………………………………..………………

Nkarta, Inc.

(Exact Name of Registrant as Specified in its Charter)

<u>Table 1: Newly Registered Securities</u>

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| | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| <br>Note 

# | <br>Security Type | <br>Security Class Title | <br>Fee Calculation Rule | <br>Amount Registered | <br>Proposed Maximum Offering Price Per Unit | <br>Maximum Aggregate Offering Price | <br>Fee Rate | <br>Amount of Registration Fee |
| 1 | Equity | Common Stock, $0.0001 par value per share, issuable pursuant to the Registrant's 2020 Performance Incentive Plan | Other | 3553926 | $1.83 | $6503684.58 | 0.0001381<br>| $898.16 |
| 2 | Equity | Common Stock, $0.0001 par value per share, issuable pursuant to the Registrant's Employee Stock Purchase Plan | Other | 710785 | $1.83 | $1300736.55 | 0.0001381<br>| $179.63 |
| Total Offering Amounts | Total Offering Amounts | Total Offering Amounts | Total Offering Amounts | 4264711 |  | $7804421.13 |  | $1077.79 |
| Total Fee Offsets | Total Fee Offsets | Total Fee Offsets | Total Fee Offsets |  |  |  |  | $0 |
| Net Fee Due | Net Fee Due | Net Fee Due | Net Fee Due |  |  |  |  | $1077.79 |

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**Fee Note #**

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.This Registration Statement covers shares of Nkarta, Inc., a Delaware corporation (the "Registrant"), common stock, par value $0.0001 per share (the "Common Stock"), that were automatically added to the shares reserved for future issuance under the Nkarta, Inc. 2020 Performance Incentive Plan and the Nkarta, Inc. Employee Stock Purchase Plan (the "Plans") on January 5, 2026 pursuant to certain provisions of the Plans that provide for an automatic increase in the share reserve each year in accordance with a formula set forth in the applicable Plan. In addition, this Registration Statement covers options and other rights to purchase or acquire the shares of Common Stock covered by this Registration Statement and, pursuant to Rule 416 under the Securities Act of 1933, as amended (the "Securities Act"), an additional indeterminate number of shares, options and rights that may be offered or issued pursuant to the Plans as a result of one or more adjustments under the Plans to prevent dilution resulting from one or more stock splits, stock dividends or similar transactions.

The offering price per share and the aggregate offering price for each Plan have been estimated solely for the purpose of calculating the amount of the registration fee. The offering price per share and the aggregate offering price are based upon the average of the high and low prices of the Registrant's common stock as reported on the Nasdaq Stock Market on December 31, 2025. The registration fee for each Plan has been calculated in accordance with Rule 457(h) and Rule 457(c) promulgated under the Securities Act.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.See Note 1.

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**EXHIBIT 107**

<u>Table 2: Fee Offset Claims and Sources</u>

Not Applicable 

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| | | | | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
|  | **Note #** | **Registrant or<br>Filer Name** | **Form or Filing Type** | **File<br> Number** | **Initial<br>Filing Date** | **Filing Date** | **Fee<br>Offset<br>Claimed** | **Security Type<br>Associated with<br>Fee Offset Claimed** | **Security Title<br>Associated with<br>Fee Offset Claimed** | **Unsold Securities<br>Associated with<br>Fee Offset Claimed** | **Unsold Aggregate<br>Offering Amount<br>Associated with<br>Fee Offset** <br>**Claimed** | **Fee Paid <br>with Fee**<br>**Offset Source** |
| **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** | **Rule 457(p)** |
| Fee Offset Claims | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Fee Offset Sources | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |

---

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