# EDGAR Filing Document

**Accession Number:** 0001505497
**File Stem:** 0001641172-25-022812
**Filing Date:** 2025-8
**Character Count:** 106464
**Document Hash:** 6bbf99344949422684699ec1a8f9d62d
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001641172-25-022812.hdr.sgml**: 20250808

**ACCESSION NUMBER**: 0001641172-25-022812

**CONFORMED SUBMISSION TYPE**: DEF 14A

**PUBLIC DOCUMENT COUNT**: 20

**CONFORMED PERIOD OF REPORT**: 20250808

**FILED AS OF DATE**: 20250808

**DATE AS OF CHANGE**: 20250808

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** BioRestorative Therapies, Inc.
- **CENTRAL INDEX KEY:** 0001505497
- **STANDARD INDUSTRIAL CLASSIFICATION:** SERVICES-MISC HEALTH & ALLIED SERVICES, NEC [8090]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 301341024
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** DEF 14A
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-37603
- **FILM NUMBER:** 251199366

**BUSINESS ADDRESS:**
- **STREET 1:** 40 MARCUS DRIVE
- **CITY:** MELVILLE
- **STATE:** NY
- **ZIP:** 11747
- **BUSINESS PHONE:** (631) 760-8100

**MAIL ADDRESS:**
- **STREET 1:** 40 MARCUS DRIVE
- **CITY:** MELVILLE
- **STATE:** NY
- **ZIP:** 11747

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** Stem Cell Assurance, Inc.
- **DATE OF NAME CHANGE:** 20101110

?xml version='1.0' encoding='ASCII'?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**SCHEDULE 14A**

**(Rule 14a-101)**

**INFORMATION REQUIRED IN PROXY STATEMENT**

**SCHEDULE 14A INFORMATION**

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

(Amendment No.)

Filed by the Registrant ☒ <br> Filed by a Party other than the Registrant ☐

---

| | |
|:---|:---|
| Check the appropriate box: | Check the appropriate box: |
| ☐ | Preliminary Proxy Statement |
| ☐ | Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) |
| ☒ | Definitive Proxy Statement |
| ☐ | Definitive Additional Materials |
| ☐ | Soliciting Material Pursuant to Section 240.14a-12 |

---

**BIORESTORATIVE THERAPIES, INC.**

(Name of Registrant as Specified in its Charter)

(Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

---

| | |
|:---|:---|
| Payment of Filing Fee (Check all boxes that apply): | Payment of Filing Fee (Check all boxes that apply): |
| ☒ | No fee required. |
| ☐ | Fee paid previously with preliminary materials. |
| ☐ | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11. |

---

**BIORESTORATIVE THERAPIES, INC.**

**40 Marcus Drive, Suite One**

**Melville, New York 11747**

**NOTICE OF ANNUAL MEETING OF sTOCKholders**

**TO BE HELD ON SEPTEMBER 18, 2025**

To the Stockholders of BioRestorative Therapies, Inc.:

**NOTICE IS HEREBY GIVEN** that the Annual Meeting of Stockholders of BioRestorative Therapies, Inc., a Nevada corporation (the "Company"), will be held on September 18, 2025, at 90 Merrick Avenue, 9<sup>th</sup> Floor, East Meadow, New York, at 10:00 a.m., local time, for the following purposes:

&nbsp;&nbsp;&nbsp;&nbsp;1. To
 elect two Class II directors to hold office until the 2028 Annual Meeting of Stockholders.

&nbsp;&nbsp;&nbsp;&nbsp;2. To
 approve an amendment to the Company's 2021 Stock Incentive Plan (the "Plan")
 to increase the number of shares of common stock authorized to be issued pursuant to the
 Plan from 6,850,000 to 9,850,000.

&nbsp;&nbsp;&nbsp;&nbsp;3. To
 ratify the selection of CBIZ CPAs P.C. as the Company's independent registered public
 accounting firm for the fiscal year ending December 31, 2025.

&nbsp;&nbsp;&nbsp;&nbsp;4. To
 hold a non-binding advisory vote on the Company's executive compensation.

&nbsp;&nbsp;&nbsp;&nbsp;5. To
 transact such other business as may properly come before the meeting.

Only stockholders of record at the close of business on July 31, 2025 are entitled to notice of and to vote at the meeting or at any adjournment thereof.

**Important notice regarding the availability of Proxy Materials:** We are sending a Notice of Internet Availability of Proxy Materials (the "Notice") to our stockholders of record and beneficial owners, unless they have directed us to provide the materials in a different manner. The Notice provides instructions on how to access and review all of the important information contained in this proxy statement, as well as how to submit a proxy by telephone or over the Internet. If you receive the Notice and would still like to receive a printed copy of our proxy materials, instructions for requesting these materials are included in the Notice. The Company plans to mail the Notice to stockholders by August 8, 2025. The proxy statement and the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2024, as filed with the Securities and Exchange Commission (the "SEC") on March 28, 2025, are available electronically to the Company's stockholders of record as of the close of business on July 31, 2025 at <u>www.proxyvote.com</u>.

---

| |
|:---|
| */s/ Lance Alstodt* |
| Lance Alstodt |
| *Chief Executive Officer* |

---

Melville, New York

August 7, 2025

**WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE SUBMIT YOUR PROXY OR VOTING INSTRUCTIONS AS SOON AS POSSIBLE. FOR SPECIFIC INSTRUCTIONS ON HOW TO VOTE YOUR SHARES, PLEASE REFER TO THE INSTRUCTIONS ON THE NOTICE REGARDING THE AVAILABILITY OF PROXY MATERIALS YOU RECEIVED IN THE MAIL OR, IF YOU REQUESTED TO RECEIVE PRINTED PROXY MATERIALS, YOUR ENCLOSED PROXY CARD. ANY STOCKHOLDER MAY REVOKE A SUBMITTED PROXY AT ANY TIME BEFORE THE MEETING BY WRITTEN NOTICE TO SUCH EFFECT, BY SUBMITTING A SUBSEQUENTLY DATED PROXY OR BY ATTENDING THE MEETING AND VOTING IN PERSON. THOSE VOTING BY INTERNET OR BY TELEPHONE MAY ALSO REVOKE THEIR PROXY BY VOTING IN PERSON AT THE MEETING OR BY VOTING AND SUBMITTING THEIR PROXY AT A LATER TIME BY INTERNET OR BY TELEPHONE.**

**BIORESTORATIVE THERAPIES, INC.**

**40 Marcus Drive, Suite One**

**Melville, New York 11747**

**PROXY STATEMENT**

**SOLICITING, VOTING AND REVOCABILITY OF PROXY**

This proxy statement is being mailed or made available to all stockholders of record at the close of business on July 31, 2025 in connection with the solicitation by our Board of Directors of proxies to be voted at the 2025 Annual Meeting of Stockholders to be held on September 18, 2025, at 10:00 a.m., local time, or any adjournment thereof. Proxy materials for the 2025 Annual Meeting of Stockholders were mailed or made available to stockholders on or about August 8, 2025.

All shares represented by proxies duly executed and received will be voted on the matters presented at the meeting in accordance with the instructions specified in such proxies. Proxies so received without specified instructions will be voted as follows:

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(i) **FOR** the nominees named in the proxy to our Board of Directors.

(ii) **FOR** the proposal to approve an amendment to our 2021 Stock Incentive Plan (the "Plan") to increase the number of shares of
 common stock authorized to be issued pursuant to the Plan from 6,850,000 to 9,850,000.

(iii) **FOR** the ratification of the selection of CBIZ CPAs P.C. as our independent registered public accounting firm for the fiscal year
 ending December 31, 2025.

(iv) **FOR** the approval of the compensation of our named executive officers.

If you are a beneficial owner of shares held in street name and you do not provide specific voting instructions to the organization that holds your shares, the organization will be prohibited under the current rules of the New York Stock Exchange from voting your shares on "non-routine" matters. This is commonly referred to as a "broker non-vote". Only Proposal 3 is considered a "routine" matter. Each remaining proposal is considered a "non-routine" matter and therefore may not be voted on by your bank or broker absent specific instructions from you. Please instruct your bank or broker so your vote can be counted.

Our Board does not know of any other matters that may be brought before the meeting nor does it foresee or have reason to believe that the proxy holder will have to vote for a substitute or alternate nominee to the Board. In the event that any other matter should come before the meeting or either nominee is not available for election, the person named in the enclosed proxy will have discretionary authority to vote all proxies not marked to the contrary with respect to such matters in accordance with his best judgment.

The total number of shares of common stock outstanding and entitled to vote as of the close of business on July 31, 2025 was 7,978,117. Each share of common stock is entitled to one vote. In addition, as of July 31, 2025, there were 1,398,158 shares of Series B preferred stock outstanding and entitled to vote. Pursuant to the Certificate of Designations of Preferred Stock with regard to the Series B preferred stock, the sole holder of the Series B preferred stock is entitled to vote such shares based on the number of shares of common stock into which such shares are convertible (currently 1,398,158); however, pursuant to such Certificate of Designations of Preferred Stock, the shares of Series B preferred stock are not convertible into shares of our common stock to the extent the sole holder would beneficially own, after such conversion, more than 9.99% of our then outstanding shares of common stock (the "Beneficial Ownership Limitation"). Since the sole holder of the Series B preferred stock has advised us that, as of July 31, 2025, it owned 434,148 shares of common stock (which represented 5.4% of the outstanding common stock), and since such holder has the right to receive 1,138,055 other shares of common stock, upon notice from it to us (subject to the Beneficial Ownership Limitation), in order to comply with the Beneficial Ownership Limitation, the shares of Series B preferred stock are not currently convertible into shares of our common stock and the sole holder of the Series B preferred stock is not entitled to vote any such shares of Series B preferred stock. The holders of one-third of the voting power of all shares of stock outstanding as of the close of business on July 31, 2025, or 2,659,373 votes, must be present at the meeting in person or by proxy in order to constitute a quorum for the transaction of business.

With regard to the election of the directors, votes may be cast in favor or withheld. The directors shall be elected by a plurality of the votes cast in favor. Accordingly, based upon there being two nominees, each person who receives one or more votes will be elected as a director. Shares of common stock as to which a stockholder withholds voting authority in the election of the directors and broker non-votes will not be counted as voting thereon and therefore will not affect the election of the nominees receiving a plurality of the votes cast.

Stockholders may expressly abstain from voting on Proposals 2, 3 and 4 by so indicating on the proxy. Abstentions are counted as present but not cast in the tabulation of votes on Proposals 2, 3 and 4. Since each of Proposals 2, 3 and 4 requires the affirmative approval of a majority of the shares present in person or represented by proxy at the meeting, entitled to vote and cast (assuming a quorum is present at the meeting), abstentions and broker non-votes will have no effect.

Any person giving a proxy in the form accompanying this proxy statement has the power to revoke it at any time before its exercise. The proxy may be revoked by filing with us written notice of revocation or a fully executed proxy bearing a later date. The proxy may also be revoked by affirmatively electing to vote in person while in attendance at the meeting. However, a stockholder who attends the meeting need not revoke a proxy given and vote in person unless the stockholder wishes to do so. Written revocations or amended proxies should be sent to us at 40 Marcus Drive, Suite One, Melville, New York 11747, Attention: Corporate Secretary. Those voting by Internet or by telephone may also revoke their proxy by voting in person at the meeting or by voting and submitting their proxy at a later time by Internet or by telephone.

The proxy is being solicited by our Board of Directors. We will bear the cost of the solicitation of proxies, including the charges and expenses of brokerage firms and other custodians, nominees and fiduciaries for forwarding proxy materials to beneficial owners of our shares. Solicitations will be made primarily by Internet availability of proxy materials and by mail, but certain of our directors, officers or employees may solicit proxies in person or by telephone, fax or email without special compensation.

**EXECUTIVE COMPENSATION**

**Summary Compensation Table**

The following Summary Compensation Table sets forth all compensation earned in all capacities during the fiscal years ended December 31, 2024 and 2023 by (i) our principal executive officer, and (ii) our two most highly compensated executive officers, other than our principal executive officer, who were serving as an executive officer as of December 31, 2024 and whose total compensation for the 2024 fiscal year, as determined by Regulation S-K, promulgated by the SEC ("Regulation S-K"), Item 402, exceeded $100,000 (the individuals falling within categories (i) and (ii) are collectively referred to as the "Named Executive Officers"):

---

| | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|
| **Name and Principal Position** | **Year** | **Salary** | **Bonus** | **Stock Awards<sup>(1)</sup>** | **Option Awards<sup>(1)</sup>** | **All Other Compensation** | **Total** |
| Lance Alstodt | 2024 | $539583 | $275000<sup>(2)</sup> | $– $| 500000 | $– $| 1314583 |
| Chief Executive Officer | 2023 | $479167 | $475000<sup>(3)</sup> | $– $| 300000 | $– $| 1254167 |
| Francisco Silva | 2024 | $514583 | $262500<sup>(2)</sup> | $– $| 450000 | $– $| 1227083 |
| VP, Research and Development | 2023 | $454167 | $450000<sup>(4)</sup> | $– $| 300000 | $– $| 1204167 |
| Robert Kristal | 2024 | $293752 | $90000<sup>(2)</sup> | $– $| 300000 | $– $| 683752 |
| Chief Financial Officer | 2023 | $240624 | $127500<sup>(5)</sup> | $– $| 250000 | $– $| 618124 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) Amounts
 reflect the aggregate grant date fair value of grants made in the fiscal year computed in accordance with stock-based accounting
 rules (FASB ASC Topic 718-Stock Compensation). Assumptions used in the calculations of these amounts are included in Note 8 to our
 consolidated financial statements included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024, available
 electronically to our stockholders.

(2) The
 2024 Bonus amount represents a discretionary bonus in consideration of 2024 services which was paid in 2025.

(3) The
 2023 Bonus amount represents (a) a discretionary bonus is the amount of $250,000 in consideration of 2023 services which was paid
 in 2024 and (b) a discretionary bonus in the amount of $225,000 in consideration of 2022 services which was paid in 2023.

(4) The
 2023 Bonus amount represents (a) a discretionary bonus in the amount of $237,500 in consideration of 2023 services which was paid
 in 2024 and (b) a discretionary bonus in the amount of $212,500 in consideration of 2022 services which was paid in 2023.

(5) The
 2023 Bonus amount represents (a) a discretionary bonus in the amount of $75,000 in consideration of 2023 services which was paid
 in 2024 and (b) a discretionary bonus in the amount of $52,500 in consideration of 2022 services which was paid in 2023.

**Pay Versus Performance (PvP) Table**

The table below is provided in accordance with Item 402(v) of Regulation S-K. We are providing the following information about the relationship between executive compensation actually paid to our CEO and our other Named Executive Officers and certain financial performance of the Company for each of the fiscal years ended December 31, 2024, 2023 and 2022:

---

| | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|
| **Fiscal Year** | **Summary Compensation Table Total**<br> **for CEO(1)** | **Compensation Actually Paid**<br> **to CEO(2)** | **Average Summary Compensation Table for Non-CEO NEOs(3)** | **Average Compensation Actually Paid to Non-CEO NEOs(4)** | **Value of Initial Fixed $100 Investment Based On Total Stockholder Return(5)** | **Net Loss(6)** |
| 2024 | $1314583 | $1202070 | $955418 | $881530 | $32.95 | $(8979381) |
| 2023 | $1254167 | $754331 | $911146 | $576729 | $40.09 | $(10417704) |
| 2022 | $452364 | $151690 | $301182 | $144872 | $63.36 | $(13222296) |

---

&nbsp;&nbsp;&nbsp;&nbsp;(1) The
 dollar amounts reported are the amounts of total compensation reported in the "Total" column of our Summary Compensation
 Table for Mr. Alstodt .

&nbsp;&nbsp;&nbsp;&nbsp;(2) The
 dollar amounts reported represent the amount of "compensation actually paid," to Mr. Alstodt as computed in accordance
 with SEC rules. The dollar amounts do not reflect the actual amount of compensation earned by or paid during the applicable year.
 In accordance with SEC rules, the following adjustments were made to total compensation to determine the compensation actually paid:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **Fiscal Year** | **Reported Summary Compensation Table Total for CEO** | **Less: Reported Value of Equity Awards(a)** | **Plus: Equity Award**<br> **Adjustments(b)** | **Equals: Compensation Actually Paid to CEO** |
| 2024 | $1314583 | $500000 | $387487 | $1202070 |
| 2023 | $1254167 | $300000 | $(199836) | $754331 |
| 2022 | $452364 | $52364 | $(248310) | $151690 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) The
 grant date fair value of equity awards represents the total of the amounts reported in the "Stock Awards" and "Option
 Awards" columns in our Summary Compensation Table for the applicable year.

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(b) The
 equity award adjustments for each applicable year include the addition (or subtraction, as applicable) of the following: (i) the
 year-end fair value of any equity awards granted in the applicable year that are outstanding and unvested as of the end of the year;
 (ii) the amount of change as of the end of the applicable year (from the end of the prior fiscal year) in fair value of any awards
 granted in prior years that are outstanding and unvested as of the end of the applicable year; (iii) for awards granted in prior
 years that vest in the applicable year, the amount equal to the change as of the vesting date (from the end of the prior fiscal year)
 in fair value; and (iv) the fair value as of the vesting date of any equity awards that are granted and vest in the applicable year.
 The amounts deducted or added in calculating the equity award adjustments are as follows:

---

| | | | |
|:---|:---|:---|:---|
| **Fair Value of Equity Awards for CEO** | **2024** | **2023** | **2022** |
| As of year-end for unvested awards granted during the year | $234854 | $59746 | $8553 |
| Year-over-year decrease of unvested awards granted in prior years | (7003) | (49407) | (213966) |
| Decrease from prior fiscal year-end for awards granted in prior years that vested during the year | (90364) | (269921) | (75416) |
| Fair value of awards granted and vested during the year | 250000 | 59746 | 32520 |
| **Total Equity Award Adjustments** | $387487 | $(199836) | $(248310) |

---

&nbsp;&nbsp;&nbsp;&nbsp;(3) The
 dollar amounts reported represent the average of the amounts reported for our NEOs as a group (excluding our CEO) in the "Total"
 column of our Summary Compensation Table in each applicable year. The names of each of the NEOs (excluding our CEO) included for
 purposes of calculating the average amounts for each applicable year are Messrs. Silva and Kristal.

(4) The
 dollar amounts reported represent the average amount of "compensation actually paid" to the NEOs as a group (excluding
 our CEO), as computed in accordance with SEC rules. The dollar amounts do not reflect the actual average amount of compensation earned
 by or paid to the NEOs as a group (excluding our CEO) during the applicable year. In accordance with the SEC rules, the following
 adjustments were made to average total compensation for the NEOs as a group (excluding our CEO) for each year to determine the compensation
 actually paid, using the same methodology described above in Note 2:

---

| | | | | |
|:---|:---|:---|:---|:---|
| **Fiscal Year** | **Average Reported Summary Compensation Table Total for Non-CEO NEOs** | **Less: Average Reported Value of Equity Awards** | **Plus: Average Equity Award Adjustments(a)** | **Equals: Average Compensation Actually Paid to Non-CEO NEOs** |
| 2024 | $955418 | $375000 | $301113 | $881530 |
| 2023 | $911146 | $275000 | $(59416) | $576729 |
| 2022 | $301182 | $26182 | $(130128) | $144872 |

---

&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(a) The
 amounts deducted or added in calculating the total average equity award adjustments are as follows:

---

| | | | |
|:---|:---|:---|:---|
| **Average Fair Value of Equity Awards for Non-CEO NEOs** | **2024** | **2023** | **2022** |
| As of year-end for unvested awards granted during the year | $176141 | $52391 | $4276 |
| Year-over-year decrease of unvested awards granted in prior years | (5231) | (24704) | (111153) |
| Decrease from prior fiscal year-end for awards granted in prior years that vested during the year | (48087) | (139495) | (39511) |
| Fair value of awards granted and vested during the year | 178290 | 52391 | 16260 |
| **Total Average Equity Award Adjustments** | $301113 | $(59416) | $(130128) |

---

&nbsp;&nbsp;&nbsp;&nbsp;(5) The
 amounts shown in the table represent the Company's Total Stockholder Return ("TSR") on an assumed investment of
 $100 in our common stock over the indicated measurement period. Cumulative TSR is calculated by dividing (i) the sum of the cumulative
 amount of dividends for the measurement period, assuming dividend reinvestment, and the difference between our common stock price
 at the end and the beginning of the measurement period by (ii) our common stock price at the beginning of the measurement period.

(6) The
 dollar amounts reported represent the amount of net loss attributable to the Company as reflected in our audited financial statements
 for the applicable year.

**Employment Agreements**

*Lance Alstodt*

Effective November 16, 2020, Mr. Alstodt was elected our Chief Executive Officer, President and Chairman of the Board. On March 18, 2021, we entered into an employment agreement with Mr. Alstodt which provides for a term ending on March 18, 2026. Pursuant to the employment agreement, Mr. Alstodt currently is entitled to receive an annual salary of $600,000 (giving effect to a $150,000 performance salary increase received in November 2021 and $50,000 annual increases in salary pursuant to his employment agreement). Concurrently with the execution of the employment agreement, we granted to Mr. Alstodt pursuant to the 2021 Plan (i) a ten year option for the purchase of 293,479 shares of our common stock at an exercise price of $47.60 per share (which exercise price was subsequently reduced to $13.50 per share and further reduced to $5.08 per share) and (ii) 146,740 restricted stock units ("RSUs"). The option vested to the extent of 50% thereof on the date of grant, 12.5% on November 4, 2021 and the balance in six equal quarterly installments commencing on December 18, 2021. The RSUs vested in three equal annual installments on the first, second and third anniversaries of the date of grant. In the event that Mr. Alstodt's employment is terminated by us without "cause", or Mr. Alstodt terminates his employment for "good reason" (each as defined in the employment agreement), Mr. Alstodt will be entitled to receive severance in an amount up to one time his then annual base salary. If Mr. Alstodt's employment with us is terminated without cause, the option granted to Mr. Alstodt will remain exercisable until its expiration date notwithstanding such termination of employment with us. In March 2022, we and Mr. Alstodt agreed that, in lieu of a $50,000 increase in his annual salary (as provided for in his employment agreement), we issued to Mr. Alstodt 12,438 RSUs (having a value of $50,000), which RSUs vested in twelve equal monthly installments. Such grant was in consideration of Mr. Alstodt deferring his right to receive the $50,000 increase in his salary for one year.

*Francisco Silva*

On March 18, 2021, we and Mr. Silva entered into an employment agreement which provides for a term ending on March 18, 2026. Pursuant to the employment agreement, Mr. Silva is currently entitled to receive an annual salary of $575,000 (giving effect to a $150,000 performance salary increase received in November 2021 and $50,000 annual increases in salary pursuant to his employment agreement). Concurrently with the execution of the employment agreement, we granted to Mr. Silva pursuant to the 2021 Plan (i) a ten year option for the purchase of 293,479 shares of our common stock at an exercise price of $47.60 per share (which exercise price was subsequently reduced to $13.50 per share and further reduced to $5.08 per share) and (ii) 146,740 RSUs. The option vested to the extent of 50% thereof on the date of grant, 12.5% on November 4, 2021 and the balance in six equal quarterly installments commencing on December 18, 2021. The RSUs vested in three equal annual installments on the first, second and third anniversaries of the date of grant. In the event that Mr. Silva's employment is terminated by us without "cause", or Mr. Silva terminates his employment for "good reason" (each as defined in the employment agreement), Mr. Silva will be entitled to receive severance in an amount up to one time his then annual base salary. If Mr. Silva's employment with us is terminated without cause, the option granted to Mr. Silva will remain exercisable until its expiration date notwithstanding such termination of employment with us. In March 2022, we and Mr. Silva agreed that, in lieu of a $50,000 increase in his annual salary (as provided for in his employment agreement), we issued to Mr. Silva 12,438 RSUs (having a value of $50,000), which RSUs vested in twelve equal monthly installments. Such grant was in consideration of Mr. Silva deferring his right to receive the $50,000 increase in his salary for one year.

**Outstanding Equity Awards at Fiscal Year-End**

The following table provides information on outstanding equity awards as of December 31, 2024 to the Named Executive Officers:

---

| | | | | | | | | | | |
|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|:---|
| | **Option Awards** | **Option Awards** | **Option Awards** | **Option Awards** | | | **Stock Awards** | **Stock Awards** | **Stock Awards** | **Stock Awards** |
| <br>**Name** | **Number of<br> Securities<br> Underlying<br> Unexercised<br> Options<br> exercisable** | **Number of<br> Securities<br> Underlying<br> Unexercised<br> Options<br> unexercisable** |  | **Equity<br> Incentive<br> Plan<br> awards:<br> Number of<br> Securities<br> Underlying<br> Exercised<br> Unearned<br> options** |<br>**Option<br> Exercise<br> price** |<br>**Option<br> Expiration<br> date** | **Number<br> of shares<br> or units of <br> stock that<br> have not<br> vested** | **Market<br> value of<br> shares of <br> units that<br> have not<br> vested** | **Equity<br> Incentive<br> Plan<br> awards:<br> Number<br> of<br> Unearned<br> shares,<br> unites or<br> other<br> rights<br> that have<br> not<br> vested** | **Equity<br> Incentive<br> Plan<br> awards:<br> Market<br> or<br> Payout<br> value of<br> unearned<br> shares,<br> units or<br> other<br> rights<br> that have<br> not<br> vested** |
| Lance Alstodt | 293479 |  |  |  | $5.08 | 3/18/31 |  | $- |  | $- |
| Lance Alstodt | 42059 |  |  |  | $5.08 | 11/4/31 |  | $- |  | $- |
| Lance Alstodt | 80072 | 26690 | (1) |  | $2.91 | 2/17/33 |  | $- |  | $- |
| Lance Alstodt | 219298 | 219298 | (2) |  | $1.45 | 2/13/34 |  | $- |  | $- |
| Francisco Silva | 6 |  |  |  | $3000 | 9/4/25 |  | $- |  | $- |
| Francisco Silva | 15 |  |  |  | $3000 | 6/10/26 |  | $- |  | $- |
| Francisco Silva | 20 |  |  |  | $3000 | 7/12/27 |  | $- |  | $- |
| Francisco Silva | 25 |  |  |  | $3000 | 10/29/28 |  | $- |  | $- |
| Francisco Silva | 293479 |  |  |  | $5.08 | 3/18/31 |  | $- |  | $- |
| Francisco Silva | 42059 |  |  |  | $5.08 | 11/4/31 |  | $- |  | $- |
| Francisco Silva | 80072 | 26690 | (1) |  | $2.91 | 2/17/33 |  | $- |  | $- |
| Francisco Silva | 197369 | 197368 | (2) |  | $1.45 | 2/13/34 |  | $- |  | $- |
| Robert Kristal | 10490 |  |  |  | $5.08 | 11/4/31 |  | $- |  | $- |
| Robert Kristal | 66726 | 22242 | (1) |  | $2.91 | 2/17/33 |  | $- |  | $- |
| Robert Kristal | 131579 | 131579 | (2) |  | $1.45 | 2/13/34 |  | $- |  | $- |

---

(1) Option is exercisable
 in four nearly equal quarterly installments beginning on February 17, 2025.

(2) Option
is exercisable in eight nearly equal quarterly installments beginning on February 13, 2025.

**Equity Award Grant Practices**

Equity awards are discretionary and are generally granted to our Named Executive Officers in the second or third week of February each year. In certain circumstances, including the hiring or promotion of an officer, the Compensation Committee may approve grants to be effective at other times. The Compensation Committee did not take material nonpublic information into account when determining the timing and terms of equity awards in 2024, and we do not time the disclosure of material nonpublic information for the purpose of affecting the value of executive compensation.

**Director Compensation**

The following table sets forth certain information concerning the compensation of our non-employee directors for the fiscal year ended December 31, 2024:

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **Name** | **Fees<br> Earned<br> or Paid<br> in Cash** | **Stock<br> Awards** | **Option<br> Awards** | **Non-Equity<br> Incentive Plan<br> Compensation** | **Total** |
| Nickolay Kukekov | $35000 | $– $| 90000<sup>(1)</sup> | $– $– $– $| 125000 |
| Patrick F. Williams | $35000 | $– $| 90000<sup>(2)</sup> | $– $– $– $| 125000 |
| David Rosa | $35000 | $– $| 90000<sup>(3)</sup> | $– $– $– $| 125000 |

---

(1) As of December 31, 2024,
 Dr. Kukekov held options for the purchase of 136,910 shares of common stock.

(2) As of December 31, 2024,
 Mr. Williams held options for the purchase of 122,164 shares of common stock.

(3) As of December 31, 2024,
 Mr. Rosa held options for the purchase of 122,164 shares of common stock.

Dr. Kukekov and Messrs. Williams and Rosa, our non-employee directors, as compensation for their services as a director, are entitled to receive per annum $35,000 in cash and $100,000 implied value in option grants.

**Security ownership of Certain beneficial**

**Owners and management** 

**Principal Stockholders**

The following table sets forth certain information regarding the beneficial ownership of our common stock, as of July 31, 2025, known by us, through transfer agent records and reports filed with the SEC, to be held by: (i) each person who beneficially owns 5% or more of the shares of common stock then outstanding; (ii) each of our directors; (iii) each of our Named Executive Officers; and (iv) all of our directors and executive officers as a group. The following table also sets forth certain information regarding the beneficial ownership of our Series B preferred stock as of July 31, 2025.

The information in this table reflects "beneficial ownership" as defined in Rule 13d-3 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). To our knowledge, and unless otherwise indicated, each stockholder has sole voting power and investment power over the shares listed as beneficially owned by such stockholder, subject to community property laws where applicable. Percentage ownership is based on 7,978,117 shares of common stock and 1,398,158 shares of Series B preferred stock outstanding as of July 31, 2025.

---

| | | | | | |
|:---|:---|:---|:---|:---|:---|
| **Name and Address of Beneficial**<br> **Owner** | **Number of<br> Shares of<br> Common Stock<br> Beneficially**<br> **Owned** |  | **Approximate<br> Percent of <br> Class** | **Number of <br> Shares of Series<br> B Preferred<br> Stock<br> Beneficially<br> Owned** | **Approximate<br> Percent of Class** |
| Directors and Executive Officers |  |  |  |  |  |
| Lance Alstodt<sup>(1)</sup> | 1304977 | <sup>(2)</sup> | 14.3% |  |  |
| Francisco Silva<sup>(1)</sup> | 1259460 | <sup>(3)</sup> | 13.9% |  |  |
| Robert Kristal<sup>(1)</sup> | 366059 | <sup>(4)</sup> | 4.4% |  |  |
| Nickolay Kukekov | 167612 | <sup>(5)</sup> | 2.1% |  |  |
| Patrick F. Williams | 152866 | <sup>(5)</sup> | 1.9% |  |  |
| David Rosa | 152866 | <sup>(5)</sup> | 1.9% |  |  |
| All directors and executive officers as a group (6 persons) | 3403840 | <sup>(6)</sup> | 30.8% |  |  |
| <u>Certain Beneficial Owners</u> |  |  |  |  |  |
| Dale Broadrick<sup>(7)</sup> | 923905 | <sup>(8)</sup> | 11.6% |  |  |
| Todd Hale Morrison | 645000 | <sup>(9)</sup> | 8.1% |  |  |
| Auctus Fund, LLC<sup>(10)</sup> |  |  |  |  |  |
| Auctus Fund Management LLC<sup>(10)</sup> |  |  |  |  |  |
| Alfred Sollami<sup>(10)</sup> |  |  |  |  |  |
| Louis Posner<sup>(10)</sup> | 837286 | (11) | 9.99% | 1398158<sup>(12)</sup> | 100% |

---

\* Less than 1%

(1) Address is c/o BioRestorative Therapies, Inc., 40 Marcus Drive, Suite One, Melville, New York 11747.

(2) Includes 1,133,105 shares of common stock issuable upon the exercise of options that are exercisable currently or within 60 days.

(3) Includes 1,091,565 shares of common stock issuable upon the exercise of options that are exercisable currently or within 60 days and 12,136 shares of common stock held by Mr. Silva in a retirement account.

(4) Includes 358,065 shares of common stock issuable upon the exercise of options that are exercisable currently or within 60 days.

(5) Represents shares of common stock issuable upon the exercise of options that are exercisable currently or within 60 days.

(6) Includes 3,056,079 shares of common stock issuable upon the exercise of options that are exercisable currently or within 60 days.

(7) Address is 3003 Brick Church Pike, Nashville, Tennessee.

(8) Based upon Amendment No.
 9 to Schedule 13D and Forms 4 filed with the SEC. Includes 477,972 shares of common stock held by Fleetco Inc. of which Mr. Broadrick
 is a 93% stockholder.

(9) Based upon Schedule 13G,
 as amended, filed with the SEC, Mr. Morrison has shared voting and dispositive power with respect to the 645,000 shares of common
 stock.

(10) Address is 545 Boylston
 Street, 2<sup>nd</sup> Floor, Boston, Massachusetts 02116.

(11) Based upon Amendment No.
 4 to Schedule 13G filed with the SEC and other filings made with the SEC. Auctus Fund, LLC ("Auctus") holds warrants
 for the purchase of up to 1,426,185 shares of our common stock. In addition, Auctus' shares of Series B preferred stock are
 convertible into an aggregate of 1,398,158 shares of our common stock. In connection with the transaction in which the above warrants
 were issued, we issued to Auctus certain shares of our common stock and have agreed to issue to Auctus, upon receipt of notice from
 Auctus, subject to the limitation discussed below, 1,138,055 shares of our common stock (the "Additional Shares"). However,
 such warrants are not exercisable for the purchase of our common stock, such Series B preferred stock is not convertible into shares
 of our common stock and the Additional Shares are not issuable to the extent Auctus would beneficially own, after such exercise,
 conversion or issuance, more than 9.99% of our outstanding shares of common stock (the "Beneficial Ownership Limitation").
 Auctus has advised that, as of July 31, 2025, it owned 434,148 shares of common stock, which represented approximately 5.4% of the
 then 7,978,117 outstanding shares of common stock, and that the Additional Shares are issuable to it, upon notice from it, to the
 extent that such issuances would not result in Auctus beneficially owning after such issuances more than 9.99% of our outstanding
 shares of common stock. Based upon the foregoing, as of July 31, 2025, 403,138 Additional Shares are issuable to Auctus (to comply
 with the Beneficial Ownership Limitation), the remaining Additional Shares are not issuable, Auctus' warrants are not currently
 exercisable for the purchase of shares of common stock and its Series B preferred stock is not currently convertible into shares
 of common stock. The number of shares of common stock beneficially owned by Auctus includes the 403,138 Additional Shares currently
 issuable to it. Without the Beneficial Ownership Limitation discussed above, Auctus would have beneficial ownership of 4,396,546
 shares of common stock.

(12) Pursuant to the Certificate
 of Designations of Preferred Stock with regard to the Series B preferred stock, Auctus, as the sole holder of the 1,398,158 outstanding
 shares of Series B preferred stock, is entitled to vote such shares based on the number of shares of common stock into which such
 shares are convertible (currently 1,398,158); however, pursuant to such Certificate of Designations of Preferred Stock, as indicated
 in footnote (11), such Series B preferred stock is not convertible into shares of common stock to the extent Auctus would beneficially
 own, after such conversion, in excess of the Beneficial Ownership Limitation. Since Auctus has advised that, as of July 31, 2025,
 it owned 434,148 shares of common stock, which represented approximately 5.4% of the outstanding shares of common stock, and, as
 indicated in footnote (11) above, 403,138 Additional Shares are issuable to it, Auctus' Series B preferred stock is not currently
 convertible into shares of common stock. Accordingly, as of July 31, 2025, Auctus, as the sole holder of the Series B preferred stock,
 is not entitled to any votes for such shares.

**Securities Authorized for Issuance Under Equity Compensation Plans**

The following table sets forth information as of December 31, 2024, with respect to compensation plans (including individual compensation arrangements) under which our common stock is authorized for issuance, aggregated as follows:

● All compensation plans previously approved by security holders; and

● All compensation plans not previously approved by security holders.

---

| | | | |
|:---|:---|:---|:---|
|  | Number of securities to be issued upon exercise of outstanding options (a) | Weighted-average exercise price of outstanding options (b) | Number of securities remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)) |
| Equity compensation plans approved by security holders | 3263467 | $2.63 | 3266736 |
| Total | 3263467 | $2.63 | 3266736 |

---

**Certain Relationships and Related Transactions**

Due to the infrequency of related party transactions, we have not formally adopted procedures for the review of, or standards for approval of, such transactions; however, our Board of Directors (or a designated committee thereof) will review related party transactions on a case-by-case basis.

**PROPOSAL 1: ELECTION OF DIRECTORS**

Two Class II directors are to be elected at the meeting to serve until the 2028 Annual Meeting of Stockholders and until their respective successors shall have been elected and have qualified or until their earlier resignation or removal.

**Nominees for Class II Director**

Each nominee is currently a member of our Board of Directors. The following table sets forth each nominee's age as of the date of the annual meeting, the positions and offices presently held with us, and the month and year in which he became a director.

---

| | | | |
|:---|:---|:---|:---|
| **Name** | **Age** | **Positions Held** | **Director Since** |
| Francisco Silva | 50 | Vice President of Research and Development, Secretary and Director | November 2020 |
| David Rosa | 61 | Director, Nominating Committee Chair | November 2021 |

---

**Francisco Silva**

Francisco Silva has served as our Vice President of Research and Development since March 2013, having also previously served in such position from April 2011 until March 2012. Mr. Silva was elected our Secretary and a director in November 2020. He served as our Research Scientist from March 2012 to June 2012 and as our Chief Scientist from June 2012 to March 2013. From 2007 to 2011, Mr. Silva served as Chief Executive Officer of DV Biologics LLC, and as President of DaVinci Biosciences, LLC, companies engaged in the commercialization of human based biologics for both research and therapeutic applications. From 2003 to 2007, Mr. Silva served as Vice President of Research and Development for PrimeGen Biotech LLC, a company engaged in the development of cell based platforms. From 2002 to 2003, he was a Research Scientist with PrimeGen Biotech and was responsible for the development of experimental designs that focused on germ line reprogramming stem cell platforms. Mr. Silva has taught courses in biology, anatomy and advanced tissue culture at California State Polytechnic University. He has obtained a number of patents relating to stem cells and has had numerous articles published with regard to stem cell research. Mr. Silva graduated from California State Polytechnic University with a degree in Biology. He also obtained a Graduate Presidential Fellowship and MBRS Fellowship from California State Polytechnic University. We believe that Mr. Silva's executive-level management experience with us since April 2011 and his extensive knowledge of the science related to our business give him the qualifications to serve as one of our directors.

**David Rosa**

David Rosa has served as one of our directors and Chair of our Board's Nominating Committee since November 2021. Mr. Rosa has served as the Chief Executive Officer, President and a director of NeuroOne Medical Technologies Corporation, or NeuroOne (Nasdaq: NMTC), since July 2017 and served as Chief Executive Officer and a director of NeuroOne, Inc., formerly its wholly-owned subsidiary, from October 2016 until December 2019, when NeuroOne, Inc. merged with and into NeuroOne. NeuroOne is committed to providing minimally invasive and hi-definition solutions for EEG recording, brain stimulation and ablation solutions for patients suffering from epilepsy, Parkinson's disease, dystonia, essential tremors, chronic pain due to failed back surgeries and other related neurological disorders that may improve patient outcomes and reduce procedural costs. From November 2009 to November 2015, Mr. Rosa served as the Chief Executive Officer and President of Sunshine Heart, Inc., n/k/a CHF Solutions, Inc. (Nasdaq: CHFS), a publicly-held early-stage medical device company. From 2008 to November 2009, he served as Chief Executive Officer of Milksmart, Inc., a company that specializes in medical devices for animals. From 2004 to 2008, Mr. Rosa served as the Vice President of Global Marketing for Cardiac Surgery and Cardiology at St. Jude Medical, Inc. He serves as a director on the board of directors of Biotricity Inc. (Nasdaq:BTCY) and Healthcare Triangle, Inc. (Nasdaq:HCTI). Mr. Rosa previously served as Chairman of Neuro Event Labs, a privately-held company in Finland, and is an Advisory Board member of SYNAPS Dx, a privately-held company in Bethesda, Maryland. We believe that Mr. Rosa's senior leadership experience in the medical device industry and his strong technical, strategic, and operational expertise give him the qualifications to serve as one of our directors.

**Directors Not Standing For Election**

---

| | | | | |
|:---|:---|:---|:---|:---|
| **Name** | **Age** | **Positions Held** | **Director Since** | **Class/Term Expiration** |
| Lance Alstodt | 54 | Chief Executive Officer, President and Chairman of the Board | November 2020 | Class III/2026 |
| Patrick F. Williams | 53 | Director, Audit Committee Chair | November 2021 | Class III/2026 |
| Nickolay Kukekov, Ph.D. | 52 | Director, Compensation Committee Chair | March 2021 | Class I/2027 |

---

**Lance Alstodt**

Lance Alstodt has served as our Chief Executive Officer, President and Chairman of the Board since November 2020. He served as our Executive Vice President and Chief Strategy Officer from October 2018 to February 2020. Since 2013, Mr. Alstodt has served as Chief Executive Officer of MedVest Consulting Corporation, an advisory and capital firm that focuses exclusively on the healthcare industry. Prior to MedVest, he was an investment banker with over 23 years of experience with respect to healthcare investment banking, including mergers and acquisitions. From 2011 to 2013, Mr. Alstodt was a Managing Director at Leerink Partners where he helped lead its medical technology sector. From 2009 to 2011, he was a Managing Director and Head of Medical Technology at Oppenheimer & Co. From 2000 to 2009, Mr. Alstodt was a Managing Director in the Healthcare Group and Global Mergers and Acquisitions Group at Bank of America Merrill Lynch. He previously spent seven years as a Vice President in the Global Mergers and Acquisitions Group at J.P. Morgan Chase, where he worked extensively on acquisitions, leveraged buyouts, private and public financings, exclusive sales and general advisory assignments. Mr. Alstodt received a degree in Economics from the State University of New York at Albany, with a secondary concentration in Finance and Marketing. We believe that Mr. Alstodt's executive-level management experience with us and other healthcare businesses and his extensive experience in the investment banking field relating to the healthcare sector give him the qualifications to serve as one of our directors.

**Patrick F. Williams**

Patrick F. Williams has served as one of our directors and Chair of our Board's Audit Committee since November 2021. Mr. Williams has more than 25 years of experience across medical device, consumer product goods and technology sectors. Appointed as Chief Financial Officer of NeuroPace Inc. ("NeuroPace") in June 2025, Mr. Williams is responsible for optimizing the financial performance of NeuroPace and ensuring the scalability of various functions to support high growth expansion. Mr. Williams served as Chief Financial Officer of STAAR Surgical Company from July 2020 to March 2025. From 2016 to 2019, he served as the Chief Financial Officer of Sientra, Inc. before transitioning to General Manager for its miraDry® business unit. From 2012 to 2016, Mr. Williams served as Chief Financial Officer of ZELTIQ Aesthetics, Inc., a publicly-traded medical device company that was acquired by Allergan. Previously, he served as Vice President in finance, strategy and investor relations roles from 2007 to 2012 at NuVasive, Inc., a San-Diego based medical device company servicing the spine sector. He has also held finance roles with Callaway Golf and Kyocera Wireless. Mr. Williams received an MBA in Finance and Management from San Diego State University and a Bachelor of Arts in Economics from the University of California, San Diego. We believe that Mr. Williams' executive-level management experience with healthcare-related businesses, including his financial management expertise, give him the qualifications to serve as one of our directors.

**Nickolay Kukekov, Ph.D.**

Nickolay Kukekov, Ph.D. has served as one of our directors since March 2021 and Chair of our Board's Compensation Committee since November 2021. For more than the past fifteen years, Dr. Kukekov has held a number of healthcare investment banking positions. He has served as Senior Managing Director of Paulson Investment Company, LLC since 2020. From 2012 to 2020, Dr. Kukekov was a founding partner of Highline Research Advisors LLC. He served as a Managing Director of Summer Street Research Partners from 2010 to 2012. From 2007 to 2009, Dr. Kukekov was a Managing Director of Paramount Capital. He served as a Vice President of Rodmen & Renshaw from 2006 to 2007. He serves as a director of Brain Scientific, Inc. and Omnia Wellness Inc. whose shares are publicly traded. Dr. Kukekov received a Bachelor of Arts degree in molecular, cellular and developmental biology from the University of Colorado at Boulder and a Ph.D. in neuroscience from Columbia University College of Physicians and Surgeons. We believe that Dr. Kukekov's extensive experience in the investment banking field relating to the healthcare sector and his strong background in regenerative medicine give him the qualifications to serve as one of our directors.

**Scientific Advisors**

**Scientific Advisory Board**

The following persons are the members of our Scientific Advisory Board:

---

| | |
|:---|:---|
| **Name** | **Principal Positions** |
| Wayne Marasco, M.D., Ph.D.<br> Chairman<br>| Professor, Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute;<br> Professor of Medicine, Harvard Medical School;<br> Principal Faculty Member, Harvard Stem Cell Institute |
| Jason Lipetz, M.D.<br> Chairman, Disc Advisory Committee | Founder, Long Island Spine Rehabilitation Medicine;<br> Chief of Spine Medicine, Northwell Health Spine Center;<br> Clinical Assistant Professor, Department of Physical Medicine and Rehabilitation, Zucker School of Medicine at Hofstra/Northwell |
| Wayne J. Olan, M.D. | Director, Interventional and Endovascular Neurosurgery;<br> Associate Professor, Neurosurgery and Radiology, George Washington University Medical Center;<br> Consulting Physician, Department of Radiology, National Institutes of Health |
| Joy Cavagnaro, Ph.D.,<br> DABT, RAC | President and Founder, Access BIO, L.C.; Fellow, Academy of Toxicological Sciences and the Regulatory Professional Society;<br> Formerly Senior Pharmacologist and Director of Quality Assurance, Food and Drug Administration's Center for Biologics Evaluation and Research |
| Harvinder Sandhu, M.D. | Orthopedic Spine Surgeon, Hospital for Special Surgery;<br> Formerly Chief of Spinal Surgery Service, UCLA Medical Center |
| Christopher Plastaras, M.D. | Clinical Director of Musculoskeletal Spine and Sports Rehabilitation Medicine and Physiatrist, MossRehab;<br> Formerly Director of The Penn Spine and Rehabilitation Center;<br> Formerly Director of Spine, Sports and Musculoskeletal Medicine Fellowship, University of Pennsylvania |

---

**Family Relationships**

There are no family relationships among any of our executive officers, directors and Scientific Advisory Board members.

**Term of Office**

We have a classified Board of Directors. Each Class II director will hold office until the 2028 annual meeting of stockholders and until his respective successor shall have been elected and have qualified or until his earlier resignation or removal. Each Class I director will hold office until the 2027 annual meeting of stockholders and until his respective successor shall have been elected and have qualified or until his earlier resignation or removal. Each Class III director will hold office until the 2026 annual meeting of stockholders and until his respective successor shall have been elected and have qualified or until his earlier resignation or removal. Each executive officer will hold office until the initial meeting of the Board of Directors following the next annual meeting of stockholders and until his successor is elected and qualified or until his or her earlier resignation or removal.

**Committees**

*Audit Committee*

The Audit Committee of the Board of Directors is responsible for overseeing our accounting and financial reporting processes and the services provided by our independent registered public accounting firm. The responsibilities and duties of the Audit Committee include the following:

● assist the Board of Directors in fulfilling its responsibilities by reviewing the financial reports provided by us to the SEC, our stockholders or to the general public, and our internal financial and accounting controls;

● oversee the appointment, compensation and retention of, and the work performed by, any independent registered public accounting firm engaged by us;

● recommend, establish and monitor procedures designed to improve the quality and reliability of the disclosure of our financial condition and results of operations;

● recommend, establish and monitor procedures designed to facilitate:

● the receipt, retention and treatment of complaints relating to accounting, internal accounting controls or auditing matters; and

● the receipt of confidential, anonymous submissions by employees of concerns regarding questionable accounting or auditing matters.

The members of our Board's Audit Committee currently are Messrs. Williams (Chair) and Rosa and Dr. Kukekov. Our Board has adopted a written charter for the Audit Committee. A copy of the charter is available on our website, <u>www.biorestorative.com.</u>

*Nominating Committee*

The Nominating Committee of the Board of Directors is responsible for assisting the Board in identifying and recruiting qualified individuals to become Board members and selecting director nominees to be presented for Board and/or stockholder approval. The members of the Nominating Committee currently are Messrs. Rosa (Chair) and Williams and Dr. Kukekov. Our Board has adopted a written charter for the Nominating Committee. A copy of the charter is available on our website, <u>www.biorestorative.com</u>. While the Nominating Committee does not have a formal policy on diversity for members of the Board of Directors, the Nominating Committee considers diversity of background, experience and qualifications in evaluating prospective Board members. The Nominating Committee will consider qualified director candidates recommended by stockholders if such recommendations are provided in accordance with the procedures set forth in the section entitled "Stockholder Proposals - Stockholder Nominees" below. The Nominating Committee evaluates all candidates based upon, among other factors, a candidate's financial literacy, knowledge of our industry, other relevant background experience, judgment, skill, integrity, the interplay of a candidate's experience with the experience of other Board members, 'independence' (for purposes of compliance with the NASDAQ Marketplace Rules), and willingness, ability and availability for service. After conducting an initial evaluation of a prospective nominee, the Nominating Committee will interview that candidate if it believes the candidate might be suitable to be a director. The Nominating Committee may also ask the candidate to meet with management. If the Nominating Committee believes a candidate would be a valuable addition to our Board of Directors, it may recommend to the full Board that candidate's nomination and election. At this time, the Nominating Committee has not adopted minimum criteria for consideration of a proposed candidate for nomination.

*Compensation Committee*

The Compensation Committee of the Board of Directors is responsible for the management of our business and affairs with respect to the compensation of our employees. The responsibilities and duties of the Compensation Committee include the following:

● review and approve corporate goals and objectives relevant to the compensation of our Chief Executive Officer, evaluate the Chief Executive Officer's performance in light of those goals and objectives, and determine and approve the Chief Executive Officer's compensation level based on this evaluation;

● review and approve corporate goals and objectives relevant to the compensation of our other executive officers, evaluate the performance of such other executive officers in light of those goals and objectives, and make recommendations to the Board with respect to the compensation of such other executive officers;

● make recommendations to the Board with respect to director compensation;

● approve any new equity compensation plan or any material change to an existing plan, approve grants pursuant to equity compensation plans and administer such plans;

● in consultation with management, oversee regulatory compliance with respect to compensation matters; and

● make recommendations to the Board with respect to any severance or similar termination payments proposed to be made to any current or former executive officer.

The members of the Compensation Committee currently are Dr. Kukekov (Chair) and Messrs. Rosa and Williams. Our Board has adopted a written charter for the Compensation Committee. A copy of the charter is available on our website, <u>www.biorestorative.com</u>.

The Compensation Committee may form and delegate authority to subcommittees and may delegate authority to one or more designated members of the Compensation Committee. Our Chief Executive Officer assists the Compensation Committee from time to time by advising on a variety of compensation matters, such as assisting the Compensation Committee in determining appropriate salaries and bonuses for our executive officers. The Compensation Committee has the authority to consult with management to assist it in its efforts.

Pursuant to its charter, the Compensation Committee also has the sole authority to retain and terminate outside compensation consultants, as well as to approve the consultant's fees and any other terms of the engagement.

**Board Leadership Structure and Role in Risk Oversight**

Our Board of Directors as a whole is responsible for our risk oversight. Our executive officers address and discuss with our Board of Directors our risks and the manner in which we manage or mitigate such risks. While our Board of Directors has the ultimate responsibility for our risk oversight, our Board of Directors works in conjunction with its committees on certain aspects of its risk oversight responsibilities. In particular, our Audit Committee focuses on financial reporting risks and related controls and procedures and our Compensation Committee strives to create compensation practices that do not encourage excessive levels of risk taking that would be inconsistent with our strategies and objectives.

Since November 2020, Lance Alstodt has served as our Chief Executive Officer and Chairman of the Board. We do not currently have a lead independent director. At this time, our Board believes that Mr. Alstodt's combined role as Chief Executive Officer and Chairman of the Board enables us to benefit from Mr. Alstodt's significant institutional and industry knowledge and experience, while at the same time promoting unified leadership and direction for our Board and executive management without duplication of effort and cost. Given our history, position, Board composition and the relatively small size of our company and management team, at this time, our Board believes that we and our stockholders are best served by our current leadership structure.

**Report of the Audit Committee**

In overseeing the preparation of the financial statements of the Company as of December 31, 2024 and 2023 and for the years then ended, the Audit Committee met with management to review and discuss all financial statements prior to their issuance and to discuss significant accounting issues. Management advised the Audit Committee that all financial statements were prepared in accordance with generally accepted accounting principles, and the Audit Committee discussed the statements with management. The Audit Committee also discussed with Marcum LLP, the Company's then independent registered public accounting firm, the matters required to be discussed by Public Company Accounting Oversight Board Auditing Standard No. 1301, *Communications with Audit Committees*, as currently in effect.

The Audit Committee received the written disclosures and the letter from Marcum required by applicable requirements of the Public Company Accounting Oversight Board regarding Marcum's communications with the Audit Committee concerning independence and the Audit Committee discussed Marcum's independence with Marcum.

On the basis of these reviews and discussions, the Audit Committee recommended to the Board of Directors that the audited financial statements be included in the Company's Annual Report on Form 10-K for the year ended December 31, 2024, for filing with the SEC.

Members of the Audit Committee

Patrick F. Williams

Nickolay Kukekov, Ph.D.

David Rosa

**Meetings**

Our Board of Directors held seven meetings during the fiscal year ended December 31, 2024.

The Audit Committee of the Board of Directors held six meetings during the fiscal year ended December 31, 2024.

The Nominating Committee of the Board of Directors did not meet during the fiscal year ended December 31, 2024.

The Compensation Committee of the Board of Directors held one meeting during the fiscal year ended December 31, 2024.

During the fiscal year ended December 31, 2024, each of our then directors, except for Mr. Rosa, attended at least 75% of the aggregate of the total number of meetings of the Board and the total number of the meetings of all committees of the Board on which they served. Mr. Rosa attended approximately 71% of such meetings. In addition to Board and committee meetings, Mr. Rosa meets regularly with our management on matters relating to the Company.

We do not have a formal policy regarding director attendance at our annual meeting of stockholders. However, all directors are encouraged to attend. Messrs. Alstodt and Silva were in attendance at last year's annual meeting of stockholders.

**Communications with Board of Directors**

Any security holder who wishes to communicate with our Board of Directors or a particular director should send the correspondence to the Board of Directors, BioRestorative Therapies, Inc., 40 Marcus Drive, Suite One, Melville, New York 11747, Attention: Corporate Secretary. Any such communication so addressed will be forwarded by the Corporate Secretary to the members or a particular member of the Board.

**Audit Committee Financial Expert**

Our Board has determined that Mr. Williams qualifies as an "audit committee financial expert," as that term is defined in Item 407(d)(5) of Regulation S-K.

**Section 16(a) Beneficial Ownership Reporting Compliance**

Section 16 of the Exchange Act requires that reports of beneficial ownership of common stock and changes in such ownership be filed with the SEC by Section 16 "reporting persons," including directors, certain officers, holders of more than 10% of the outstanding common stock and certain trusts of which reporting persons are trustees. We are required to disclose in this proxy statement each reporting person whom we know to have failed to file any required reports under Section 16 on a timely basis during the fiscal year ended December 31, 2024. To our knowledge, based solely on a review of copies of Forms 3, 4 and 5 filed with the SEC, during the fiscal year ended December 31, 2024, our officers, directors and 10% stockholders complied with all Section 16(a) filing requirements applicable to them, except that Dale Broadrick, a 10% stockholder, filed a Form 4 late (reporting one transaction).

**Director Independence**

**Board of Directors**

Our Board of Directors is currently comprised of Lance Alstodt (Chairman), Francisco Silva, Nickolay Kukekov, Ph.D., Patrick F. Williams and David Rosa. Each of Dr. Kukekov and Messrs. Williams and Rosa is currently an "independent director" based on the definition of independence in Listing Rule 5605(a)(2) of the listing standards of The Nasdaq Stock Market.

**Audit Committee**

The members of our Board's Audit Committee currently are Messrs. Williams (Chair) and Rosa and Dr. Kukekov, each of whom is an "independent director" based on the definition of independence in Listing Rule 5605(a)(2) of the listing standards of The Nasdaq Stock Market and Rule 10A-3(b)(1) under the Exchange Act.

**Nominating Committee**

The members of our Board's Nominating Committee currently are Messrs. Rosa (Chair) and Williams and Dr. Kukekov, each of whom is an "independent director" based on the definition of independence in Listing Rule 5605(a)(2) of the listing standards of The Nasdaq Stock Market.

**Compensation Committee**

The members of our Board's Compensation Committee currently are Dr. Kukekov (Chair) and Messrs. Williams and Rosa, each of whom is an "independent director" based on the definition of independence in Listing Rule 5605(a)(2) of the listing standards of The Nasdaq Stock Market.

**Code of Ethics for Senior Financial Officers**

Our Board of Directors has adopted a Code of Business Conduct and Ethics for our principal executive officer, principal financial officer, principal accounting officer or controller, or persons performing similar functions. A copy of the Code of Business Conduct and Ethics is posted on our website, www.biorestorative.com. We intend to satisfy the disclosure requirement under Item 5.05(c) of Form 8-K regarding an amendment to, or a waiver from, our Code of Business Conduct and Ethics by posting such information on our website, <u>www.biorestorative.com.</u>

**Insider Trading Policy**

We have adopted an insider trading policy governing the purchase, sale and/or other disposition of our company's securities by directors, officers and employees that is designed to promote compliance with insider trading laws, rules and regulations, as well as procedures designed to further the foregoing purposes. A copy of our insider trading policy is filed as an exhibit to our Annual Report on Form 10-K for the fiscal year ended December 31, 2024, available electronically to our stockholders. In addition, from time to time, we may engage in transactions in our company's securities. It is our intent to comply with applicable laws and regulations relating to insider trading.

**Recommendation**

**The Board of Directors recommends a vote FOR both Class II nominees.**

**PROPOSAL 2: AMENDMENT TO THE COMPANY'S 2021 STOCK INCENTIVE PLAN**

Our Board of Directors has approved, subject to stockholder approval, an amendment to the BioRestorative Therapies, Inc. 2021 Stock Incentive Plan (the "Plan") to increase the number of shares of common stock authorized to be issued thereunder from 6,850,000 to 9,850,000. The amendment to the Plan is being submitted to the stockholders for approval.

As of July 31, 2025, options for the purchase of 5,262,973 shares of common stock, net of forfeitures, 318,356 restricted stock units ("RSUs") and 1,442 shares of common stock had been granted pursuant to the Plan. As of such date, 1,267,229 shares were reserved for future grants under the Plan (without giving effect to the amendment to the Plan increasing the number of shares authorized to be issued under the Plan to 9,850,000, subject to stockholder approval). See "Plan Benefits" below for additional details.

The Plan was originally adopted by our Board on March 18, 2021. Pursuant to the Plan, up to 1,175,000 shares of common stock were initially authorized to be issued. Stockholder approval of the Plan was obtained on August 17, 2021. On December 10, 2021, our Board, subject to stockholder approval, increased the number of shares authorized to be issued under the Plan from 1,175,000 to 2,500,000 and revised certain provisions of the Plan to make clear the authority of our Board and Compensation Committee to reduce the exercise price of options granted pursuant to the Plan (either directly or pursuant to the cancellation of an outstanding option and the regrant of the option at a reduced exercise price). Stockholder approval was obtained on November 3, 2022. On July 13, 2023, our Board, subject to stockholder approval, increased the number of shares authorized to be issued under the Plan from 2,500,000 to 3,850,000. Stockholder approval was obtained on September 13, 2023. Effective as of July 23, 2024, our Board, subject to stockholder approval, increased the number of shares authorized to be issued under the Plan from 3,850,000 to 6,850,000. Stockholder approval was obtained on September 19, 2024. Effective as of July 17, 2025, our Board, subject to stockholder approval, increased the number of shares authorized to be issued under the Plan from 6,850,000 to 9,850,000.

The Plan plays an important role in our efforts to attract and retain employees of outstanding ability and to align the interests of employees with those of the stockholders through increased stock ownership. As discussed below, the Plan is also designed to provide incentives to our non-employee directors, consultants and advisors.

**The following statements include summaries of certain provisions of the Plan. The statements do not purport to be complete and are qualified in their entirety by reference to the provisions of the Plan, a copy of which is available at our offices.**

**Purpose**

The purpose of the Plan is to promote the success and enhance the value of the Company and its subsidiaries by linking the individual interests of employees, consultants, advisors and members of our Board of Directors to those of our stockholders and by providing such individuals with an incentive for outstanding performance to generate superior returns to our stockholders. The Plan is further intended to provide flexibility to the Company and its subsidiaries in their ability to motivate, attract, and retain the services of those individuals upon whose judgment, interest, and special effort the successful conduct of our operation is largely dependent.

**Administration**

The Plan provides for its administration by our Board of Directors, or a committee (the "Committee") appointed by the Board. The following discussion of the Plan assumes that the Plan is administered by the Compensation Committee.

The Committee has authority (subject to certain restrictions) to select from the group of eligible employees, non-employee directors, consultants and advisors the individuals or entities to whom awards will be granted under the Plan, and to determine the times at which awards will be granted and the terms of such grants. The Committee is authorized to interpret the Plan and the interpretation and construction by the Committee of any provision of the Plan or of any award granted under the Plan shall be final and conclusive. The receipt of awards under the Plan by directors or any members of the Committee shall not preclude their vote on any matters in connection with the administration or interpretation of the Plan.

As amended, pursuant to the Plan, the Committee is authorized to reduce the exercise price of granted options (either directly or pursuant to a cancellation of the options and the regrant of an option at a reduced exercise price equal to the then fair market value (as defined in the Plan) of our common stock).

**Eligibility**

Subject to certain limitations as set forth in the Plan, options to purchase shares may be granted thereunder to persons or entities who, in the case of incentive stock options, are employees of the Company or, in the case of non-qualified stock options, are employees or non-employee directors of, or certain consultants or advisors to, the Company. Subject to certain limitations as set forth in the Plan, restricted stock, RSUs, stock appreciation rights and other stock awards may be granted thereunder to persons or entities who are employees or non-employee directors of, or certain consultants or advisors to, the Company.

As of July 31, 2025, 13 employees, three non-employee directors and six members of our Scientific Advisory Board were eligible to receive awards under the Plan.

**Options**

*Nature of Options*

 

The Committee may grant options under the Plan which are intended to either qualify as "incentive stock options" within the meaning of Section 422 of the Code or not so qualify. We refer to options that do not so qualify as "non-qualified stock options." The Federal income tax consequences relating to the grant and exercise of incentive stock options and non-qualified stock options are described below under "Federal Income Tax Consequences."

 

*Option Price*

 

The option price of the shares subject to an incentive stock option or a non-qualified stock option may not be less than the fair market value of the common stock on the date upon which such option is granted. In addition, in the case of a recipient of an incentive stock option who, at the time the option is granted, owns more than 10% of the total combined voting power of all classes of our stock or of a parent or of any of our subsidiaries, the option price of the shares subject to such option must be at least 110% of the fair market value of the common stock on the date upon which such option is granted.

On July 31, 2025, the last reported sale price for our common stock on The Nasdaq Capital Market was $1.47 per share.

*Exercise of Options*

 

An option granted under the Plan shall be exercised by the delivery by the holder to our Secretary at our principal office of a written or electronic notice of the number of shares with respect to which the option is being exercised. The notice must be followed by payment of the full option price of such shares which must be made by the holder's delivery of (i) cash or check in such amount, (ii) previously acquired common stock, the fair market value of which shall be determined as of the date of exercise, (iii) other form of legal consideration acceptable to the Committee, or (iv) any combination of the foregoing.

*Duration of Options*

 

No incentive stock option granted under the Plan shall be exercisable after the expiration of ten years from the date of its grant. However, if an incentive stock option is granted to a 10% stockholder, the option shall not be exercisable after the expiration of five years from the date of its grant.

Non-qualified stock options granted under the Plan shall be exercisable for a period of up to ten years from the date of their grant.

*Non-Transferability*

 

Options granted under the Plan are not transferable otherwise than by will or the laws of descent and distribution and such options are exercisable, during a holder's lifetime, only by the grantee; provided, however, that a non-qualified stock option granted under the Plan may, upon the approval of the Committee, be transferred in whole or in part during a grantee's lifetime to certain family members of a grantee through a gift or domestic relations offer.

*Death, Disability or Termination of Employment*

 

Subject to the terms of the agreement pursuant to which the options are granted, if the employment of an employee or the services of a non-employee director, consultant or advisor shall terminate other than for cause or by reason of death or disability, such option may be exercised at any time within three months after such termination, but in no event after the expiration of the option.

Subject to the terms of the agreement pursuant to which the options are granted, if an option holder under the Plan dies while employed by us or while serving as a non-employee director of, or consultant or advisor to, us, then such option may be exercised by the estate of the employee, non-employee director, consultant or advisor, or by a person who acquired such option by bequest or inheritance from the deceased option holder, at any time within twelve months after his death.

Subject to the terms of the stock option agreement pursuant to which the options are granted, if the holder of an option under the Plan ceases employment or services because of permanent and total disability (as defined in the Plan) while employed by, or while serving as a non-employee director of, or consultant or advisor to, us, then such option may be exercised at any time within twelve months after his termination of employment, termination of directorship, or termination of consulting or advisory arrangement or agreement due to the disability.

**Stock Appreciation Rights**

The Committee may grant stock appreciation rights (an "SAR") to such persons eligible under the Plan as selected from time to time. SARs shall be granted at such times, in such amounts and under such other terms and conditions as the Committee shall determine. An SAR entitles the grantee to exercise the SAR, in whole or in part, in exchange for payment of shares of our common stock, cash or a combination thereof, as determined by the Committee, equal in value to the excess of the fair market value of the shares of our common stock underlying the SAR, determined on the date of exercise, over the fair market value of our common stock underlying the SAR on the date of grant.

No SAR granted under the Plan shall be exercisable after the expiration of ten years from the date of its grant.

**Restricted Stock and Restricted Stock Unit Grants**

The Committee may grant restricted stock and RSUs under the Plan to any individual or entity eligible to receive restricted stock or RSUs. A restricted stock or RSU award is an award of shares of our common stock that is subject to certain conditions on vesting and to certain restrictions on transferability.

Shares granted pursuant to a grant of restricted stock or RSUs shall vest as determined by the Committee. Except as otherwise provided in the award agreement, a grantee shall forfeit all shares not previously vested, if any, at such time as the grantee is no longer employed by, or serving as a director of, or rendering consulting or advisory services to, us.

In determining the vesting requirements with respect to a grant of restricted stock or RSUs, the Committee may impose such restrictions on any shares granted as it may deem advisable including, without limitation, restrictions relating to length of service, corporate performance, attainment of individual or group performance goals and federal or state securities laws.

During the period that restricted stock is unvested, the grantee will be the record owner of the restricted stock and shall be entitled to receive all dividends and other distributions paid with respect to such shares while they are so restricted; however, if any dividends or distributions are payable in shares of our stock, cash and/or other property during an applicable period of restriction, the shares, cash and/or other property deliverable shall be held by us until such time as the vesting restrictions with respect to the restricted stock are satisfied.

A holder of RSUs shall not have any rights of a stockholder with respect to the shares of common stock underlying the RSUs unless and until the RSUs vest and are settled by the issuance of shares of common stock.

**Amendment and Termination**

The Plan (but not the options or other stock awards previously granted thereunder) shall terminate on March 18, 2031, ten years from the date that it was adopted by our Board. Subject to certain limitations, the Plan may be amended or modified from time to time or terminated at an earlier date by our Board or by the stockholders.

**Federal Income Tax Consequences**

The following discussion is intended only as a brief summary of the federal income tax rules relevant to stock options, restricted stock and RSUs granted under the Plan. These rules are highly technical and subject to change. The following discussion is limited to the federal income tax rules relevant to us and to the individuals who are citizens or residents of the United States. The discussion does not address state, local or foreign income tax consequences.

*Non-qualified Stock Options*

Under the Code and the Treasury Department Regulations, a non-qualified stock option does not ordinarily have a readily ascertainable fair market value when it is granted. This rule will apply to our grant of non-qualified stock options. Consequently, the grant of a non-qualified stock option to an optionee will result in neither income to him or her nor a deduction to us. Instead, the optionee will recognize compensation income at the time he or she exercises the non-qualified stock option in an amount equal to the excess, if any, of the then fair market value of the shares transferred to the optionee over the option price. Subject to the applicable provisions of the Code and the Treasury Department Regulations regarding withholding of tax, a deduction will be allowable to us in the year of exercise in the same amount as is includable in the optionee's income.

For purposes of determining the optionee's gain or loss on the sale or other disposition of the shares transferred to him or her upon exercise of a non-qualified stock option, the optionee's basis in such shares will be the sum of the optionee's option price plus the amount of compensation income recognized by him or her on exercise. Such gain or loss will be capital gain or loss and will be long-term or short-term depending upon the holding period requirement for the shares. No part of any such gain will be an item of tax preference for purposes of the alternative minimum tax.

*Incentive Stock Options*

Options granted under the Plan which qualify as incentive stock options under Section 422 of the Code will be treated as follows:

Except to the extent that the alternative minimum tax rule described below applies, no tax consequences will result to the optionee or us from the grant of an incentive stock option to, or the exercise of an incentive stock option by, the optionee. Instead, the optionee will recognize gain or loss when he or she sells or disposes of the shares transferred to him or her upon exercise of the incentive stock option. For purposes of determining such gain or loss, the optionee's basis in such shares will be his or her option price. If the optionee holds the shares acquired upon exercise for the requisite holding period set forth in the Code, the optionee will realize long-term capital gain treatment upon their sale or disposition.

Generally, we will not be allowed a deduction with respect to an incentive stock option. However, if an optionee fails to meet the foregoing holding period requirements (a so-called disqualifying disposition), any gain recognized by the optionee upon the sale or disposition of the shares transferred to him or her upon exercise of an incentive stock option will be treated in the year of such sale or disposition as ordinary income, rather than capital gain, to the extent of the excess, if any, of the fair market value of the shares at the time of exercise (or, if less, in certain cases the amount realized on such sale or disposition) over their option price, and in that case we will be allowed a corresponding deduction.

For purposes of the alternative minimum tax, the amount, if any, by which the fair market value of the shares transferred to the optionee upon such exercise exceeds the option price will be included in determining the optionee's alternative minimum taxable income. In addition, for purposes of such tax, the basis of such shares will include such excess.

To the extent that the aggregate fair market value (determined at the time the option is granted) of the stock with respect to which incentive stock options are exercisable for the first time by the optionee during any calendar year exceeds $100,000, such options will not be incentive stock options. In this regard, upon the exercise of an option which is deemed, under the rule described in the preceding sentence, to be in part an incentive stock option and in part a non-qualified stock option, under existing Internal Revenue Service guidelines, we may designate which shares issued upon exercise of such options are incentive stock options and which shares are non-qualified stock options. In the absence of such designation, a pro rata portion of each share issued is to be treated as issued pursuant to the exercise of an incentive stock option and the balance of each share treated as issued pursuant to the exercise of a non-qualified stock option.

*Other Stock-Based Awards*

The income tax consequences of the other stock-based awards will depend on how such awards are structured. In the case of the grant of an RSU, a participant will not be in receipt of taxable income at the time of grant. On delivery, a participant will be in receipt of ordinary income in an amount equal to the fair market value of the acquired shares of common stock.

**New Plan Benefits**

The benefits that will be awarded or paid under the Plan are not currently determinable (see, however, "Eligibility" above). Awards granted under the Plan are within the discretion of the Committee, and the Committee has not determined future awards or who might receive them.

**Plan Benefits**

The following table sets forth certain information regarding options and RSUs granted under the Plan, net of forfeitures, as of July 31, 2025, to (i) each Named Executive Officer, (ii) all current executive officers as a group, (iii) all current directors who are not executive officers as a group, (iv) each nominee for election as a director, (v) each associate of any such directors, executive officers or nominees, (vi) each other person who received 5% of the options granted and (vii) all employees, including current officers who are not executive officers, as a group:

---

| | | | |
|:---|:---|:---|:---|
| **Name and Position** | **Common Stock**<br> **Underlying**<br> **Options Granted** | **Weighted Average**<br> **Exercise Price**<br> **Per Share** | **Restricted Stock Units Granted** |
| Lance Alstodt <br>Chief Executive Officer, President and Chairman of the Board | 1672781<sup>(1)</sup> | $2.75 | 159178<sup>(8)</sup> |
| Francisco Silva <br>Vice President of Research and Development | 1606082<sup>(2)</sup> | $2.91 | 159178<sup>(8)</sup> |
| Robert Kristal <br>Chief Financial Officer | 529108<sup>(3)</sup> | $2.09 |  |
| All current executive officers as a group | 3807971<sup>(4)</sup> | $2.73 | 318356<sup>(8)</sup> |
| All current directors who are not executive officers as a group | 539134<sup>(5)</sup> | $2.32 |  |
| Jason Lipetz, M.D., Chairman, Disc Advisory Committee of Scientific Advisory Board | 584900<sup>(6)</sup> | $2.19 |  |
| All employees, including all current officers who are not executive officers, as a group | 243322<sup>(7)</sup> | $1.99 |  |

---

(1) Such
 options have vested to the extent of 1,099,021 shares.

(2) Such options
 have vested to the extent of 1,060,222 shares.

(3) Such options
 have vested to the extent of 336,057 shares.

(4) Such options
 have vested to the extent of 2,495,300 shares.

(5) Such options
 have vested to the extent of 447,028 shares.

(6) Such options
 have vested to the extent of 488,322 shares.

(7) Such options
 have vested to the extent of 139,195 shares.

(8) Such RSUs
 have vested.

**Securities Authorized for Issuance Under Equity Compensation Plans**

The following table sets forth information as of December 31, 2024, with respect to compensation plans (including individual compensation arrangements) under which our shares of common stock are authorized for issuance, aggregated as follows:

● All compensation plans previously approved by security holders; and

● All compensation plans not previously approved by security holders.

**Equity Compensation Plan Information**

---

| | | | |
|:---|:---|:---|:---|
|  | Number of securities to be issued upon exercise of outstanding options (a) | Weighted-average exercise price of outstanding options (b) | Number of securities remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)) |
| Equity compensation plans approved by security holders | 3263467 | $2.63 | 3266736 |
| Total | 3263467 | $2.63 | 3266736 |

---

**Vote Required**

**The approval of the amendment to the Plan requires the affirmative vote of stockholders who hold a majority of the voting power present in person or represented by proxy at the meeting.**

**Recommendation**

**The Board of Directors recommends a vote FOR approval of the amendment to the Plan.**

**PROPOSAL 3:** **RATIFICATION OF SELECTION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM**

The Audit Committee of our Board of Directors has selected CBIZ CPAs P.C. ("CBIZ CPAs") as our independent registered public accounting firm for the fiscal year ending December 31, 2025.

Although ratification by stockholders is not required by our organizational documents or other applicable law, our Board of Directors has determined that requesting ratification by stockholders of the appointment of CBIZ CPAs as our independent registered public accounting firm for the fiscal year ending December 31, 2025 is a matter of good corporate practice. If stockholders do not ratify the selection, the Audit Committee may reconsider whether or not to retain CBIZ CPAs, but may still determine to retain them. Even if the selection is ratified, the Audit Committee, in its discretion, may change the appointment at any time during the year if it determines that such a change would be in the best interests of us and our stockholders.

Marcum LLP served as our independent registered public accounting firm with respect to the fiscal years ended December 31, 2022, 2023 and 2024. On November 1, 2024, CBIZ CPAs acquired the attest business of Marcum. On April 15, 2025, Marcum informed us that it resigned as our independent registered public accounting firm as a result of such acquisition. On April 16, 2025, our Audit Committee engaged CBIZ CPAs as our independent registered public accounting firm.

The audit report of Marcum on our consolidated financial statements as of and for the fiscal years ended December 31, 2024 and 2023 did not contain an adverse opinion or a disclaimer of opinion and was not qualified or modified as to uncertainty, audit scope, or accounting principles.

During the fiscal years ended December 31, 2024 and 2023, and the subsequent interim period through April 16, 2025, there were no disagreements with Marcum on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedure, which disagreement(s), if not resolved to the satisfaction of Marcum, would have caused it to make reference to the subject matter of the disagreement(s) in connection with its report.

During the fiscal years ended December 31, 2024 and 2023, and the subsequent interim period through April 16, 2025, we had the following "reportable events" (as such term is defined in Item 304(a)(1)(v) of Regulation S-K): As disclosed in Part II, Item 9A of our Form 10-Ks for the fiscal years ended December 31, 2024 and 2023, there were material weaknesses identified in internal control over financial reporting related to lack of adherence to formal policies and procedures, lack of risk assessment procedures on internal controls to detect financial reporting risks in a timely manner, lack of design and implementation of effective controls to achieve complete and accurate financial reporting and disclosures, including documented controls over the preparation and review of journal entries, account reconciliations and income taxes, and lack of design and implementation of effective controls over the accounting for warrants issued in connection with equity financings.

No consultations occurred between us and CBIZ CPAs during the two most recent fiscal years and the subsequent interim period prior to CBIZ CPAs's appointment regarding either (a) the application of accounting principles to a specific completed or proposed transaction, the type of audit opinion that might be rendered on our financial statements, or other information provided that was considered by us in reaching a decision as to an accounting, auditing or financial reporting issue, or (b) any matter that was the subject of a disagreement (as defined in Item 304(a)(1)(iv) of Regulation S-K) or a reportable event (as described in Item 304(a)(1)(v) of Regulation S-K).

It is not expected that a representative of CBIZ CPAs will attend the meeting.

The following is a summary of the fees billed or expected to be billed to us by Marcum LLP, our independent registered public accountants, for professional services rendered with respect to the fiscal years ended December 31, 2024 and 2023:

---

| | | |
|:---|:---|:---|
|  | **2024** | **2023** |
|  | **Marcum** <br> **LLP** | **Marcum** <br> **LLP** |
| Audit fees <sup>(1)</sup> | $138000 | $101500 |
| Audit-related fees <sup>(2)</sup> | 35000 | 37000 |
| Tax fees <sup>(3)</sup> |  |  |
| All other fees <sup>(4)</sup> | - | - |
|  | $173000 | $138500 |

---

(1) Audit
 Fees consist of fees billed and expected to be billed for services rendered for the audit of our consolidated financial statements
 for the fiscal years ended December 31, 2024 and 2023, and the review of our condensed consolidated financial statements included
 in our Quarterly Reports on Form 10-Q.

(2) Audit-Related
 Fees consist of fees billed for assurance and related services that are reasonably related to the performance of the audit of our
 financial statements and in connection with the filing of Forms S-1, S-3 and S-8 registration statements and are not reported under
 "Audit Fees."

(3) Tax
 Fees consist of fees billed for professional services related to preparation of our U.S. federal and state income tax returns and
 tax advice.

(4) All
 Other Fees consist of fees billed for products and services provided by our independent registered public accountants, other than
 those disclosed above.

The Audit Committee is responsible for the appointment, compensation and oversight of the work of the independent registered public accounting firm and approves in advance any services to be performed by the independent registered public accounting firm, whether audit-related or not. The Audit Committee reviews each proposed engagement to determine whether the provision of services is compatible with maintaining the independence of the independent registered public accounting firm. The fees shown above were pre-approved either by our Board or our Audit Committee.

**Vote Required**

**The ratification of the selection of CBIZ CPAs P.C. as our independent registered public accounting firm for the fiscal year ending December 31, 2025 requires the affirmative vote of stockholders who hold a majority of the voting power present in person or represented by proxy at the meeting and entitled to vote.**

**Recommendation**

**The Board of Directors recommends that stockholders vote FOR the ratification of the selection of CBIZ CPAs P.C. as our independent registered public accounting firm for the fiscal year ending December 31, 2025.**

**PROPOSAL 4: ADVISORY VOTE ON THE COMPENSATION OF**

**THE COMPANY'S NAMED EXECUTIVE OFFICERS**

In accordance with the rules of the SEC, we are providing our stockholders with the opportunity to cast a non-binding advisory vote on the compensation of our Named Executive Officers as disclosed pursuant to Item 402(m) through (q) of Regulation S-K, including the compensation tables and narrative discussion in this proxy statement.

The compensation structure established by our Compensation Committee is designed to attract and retain motivated executives who substantially contribute to our long-term success and the creation of stockholder value, to reward executives when we perform financially or operationally well, to align the financial interests of our executives with the interests of our stockholders, and to be competitive within our industry. We believe that our philosophy and practices have resulted in executive compensation decisions that are appropriate and that have benefited us over time.

We are requesting stockholder approval of the compensation of our Named Executive Officers as disclosed in this proxy statement. This proposal, commonly known as a "say-on-pay" proposal, gives our stockholders the opportunity to express their views on our Named Executive Officer compensation. Because the stockholder vote is advisory, it is not binding on us or our Board of Directors. However, our Board and the Compensation Committee, which is responsible for designing and administering our executive compensation program, value the opinions that our stockholders express in their votes. The whether to recommend any changes or modifications to our executive compensation policies and practices as a result of such votes.

We are asking our stockholders to indicate their support for our Named Executive Officer compensation through the following resolution:

"**RESOLVED**, that the stockholders approve the compensation paid to our Named Executive Officers, as disclosed pursuant to Item 402 of Regulation S-K, including the compensation tables and narrative discussion in this proxy statement."

**Vote Required**

**The affirmative vote of the holders of a majority of the voting power present at the meeting, in person or by proxy, is required for approval of this proposal.**

**Recommendation**

**The Board of Directors recommends a vote FOR approval of the compensation of our executive officers as disclosed in this proxy statement.**

**STOCKHOLDER PROPOSALS**

Stockholder proposals intended to be presented at our next annual meeting of stockholders pursuant to the provisions of Rule 14a-8 of the SEC, promulgated under the Exchange Act, must be received at our offices in Melville, New York, by April 9, 2026, for inclusion in our proxy statement and form of proxy relating to such meeting.

The following requirements with respect to stockholder proposals and stockholder nominees to our Board of Directors are included in our bylaws.

**Stockholder Proposals**

In order for a stockholder to make a proposal at an annual meeting of stockholders, under our bylaws, timely notice must be received by us in advance of the meeting. To be timely, a stockholder's notice must be delivered to or mailed and received by our Secretary at our principal executive offices not less than 45 days nor more than 75 days prior to the one-year anniversary of the date on which we first mailed the proxy materials for the preceding year's annual meeting of stockholders; provided, however, that if the meeting is convened more than 30 days prior to or delayed more than 30 days after the anniversary of the preceding year's annual meeting or if no annual meeting was held in the preceding year, to be timely a stockholder's notice must be received not later than the close of business on the later of (i) the 90<sup>th</sup> day before such annual meeting or (ii) the 10<sup>th</sup> day following the day on which public announcement of the date of such meeting is first made.

A stockholder's notice must set forth as to each matter the stockholder proposes to bring before the annual meeting certain information regarding the proposal, including the following:

● a brief description of the business desired to be brought before the meeting, the reasons for conducting such business at the meeting and any material interest (financial or other) of such stockholder in such business; and

● with respect to the stockholder proposing such business or the beneficial owner, if any, on whose behalf the proposal is made: (i) the name and address of each such party; (ii) the class and number of shares that are beneficially owned by each such party; (iii) any derivative instruments that are beneficially owned by each such party and any other opportunity to profit or share in any profit derived from any increase or decrease in the value of our capital stock; (iv) any proxy or arrangement pursuant to which either party has a right to vote any shares; (v) any short interest in any of our securities; (vi) any rights to dividends that are separated from our underlying shares; (vii) any proportionate interest in our capital stock or any derivative instruments held by a general or limited partnership in which either party is a general partner or beneficially owns a general partner; (viii) any performance-related fees (other than an asset-based fee) that each such party is entitled to based on any increase or decrease in the value of our capital stock or any derivative instruments; (ix) any other information relating to each such party that would be required to be disclosed in a proxy statement; and (x) a statement as to whether or not each such party will deliver a proxy statement and form of proxy to holders of at least that percentage of voting power of all of our shares of capital stock required under applicable law to carry the proposal.

**Stockholder Nominees**

In order for a stockholder to nominate a candidate for director at an annual meeting of stockholders, under our bylaws, timely notice of the nomination must be received by us in advance of the meeting. To be timely, a stockholder's notice must be delivered to or mailed and received by our Secretary at our principal executive offices not less than 45 days nor more than 75 days prior to the one-year anniversary of the date on which we first mailed the proxy materials for the preceding year's annual meeting of stockholders; provided, however, that if the meeting is convened more than 30 days prior to or delayed more than 30 days after the anniversary of the preceding year's annual meeting or if no annual meeting was held in the preceding year, to be timely a stockholder's notice must be so received not later than the close of business on the later of (i) the 90<sup>th</sup> day before such annual meeting or (ii) the 10<sup>th</sup> day following the day on which public announcement of the date of such meeting is first made.

The stockholder sending the notice of nomination must describe various matters, including the following:

● as to each person whom the stockholder proposes to nominate for election as a director, all information relating to such person as would be required to be disclosed in solicitations of proxies for election of such nominee as a director pursuant to Regulation 14A under the Exchange Act;

● with respect to the stockholder proposing such nomination or the beneficial owner, if any, on whose behalf the nomination is made: (i) the name and address of each such party; (ii) the class and number of shares that are beneficially owned by each such party; (iii) any derivative instruments that are beneficially owned by each such party and any other opportunity to profit or share in any profit derived from any increase or decrease in the value of our capital stock; (iv) any proxy or arrangement pursuant to which either party has a right to vote any shares; (v) any short interest in any of our securities; (vi) any rights to dividends that are separated from our underlying shares; (vii) any proportionate interest in our capital stock or any derivative instruments held by a general or limited partnership in which either party is a general partner or beneficially owns a general partner; (viii) any performance-related fees (other than an asset-based fee) that each such party is entitled to based on any increase or decrease in the value of our capital stock or any derivative instruments; (ix) any other information relating to each such party that would be required to be disclosed in a proxy statement; and (x) a statement as to whether or not each such party will deliver a proxy statement and form of proxy to holders of at least that percentage of voting power of all of the shares of our capital stock reasonably believed to be sufficient to elect the nominee or nominees proposed to be nominated; and

● the written consent by the nominee, agreeing to serve as a director if elected.

These requirements are separate from and in addition to the requirements a stockholder must meet to have a proposal included in our proxy statement.

Any notice given pursuant to the foregoing requirements must be sent to our Secretary at 40 Marcus Drive, Suite One, Melville, New York 11747. **The foregoing is only a summary of the provisions of our bylaws that relate to stockholder proposals and stockholder nominations for director. Any stockholder desiring a copy of our bylaws will be furnished one without charge upon receipt of a written request therefor.**

**Universal Proxy Rules**

In addition to satisfying the requirements under our bylaws, in order to comply with the SEC's universal proxy rules, stockholders who intend to solicit proxies in support of director nominees, other than the Company's nominees, must provide notice that sets forth the information required by Rule 14a-19 under the Exchange Act, which notice must be postmarked or transmitted electronically to the Company at our principal executive offices no later than 60 days prior to the anniversary date of this annual meeting of stockholders (i.e., for our 2026 annual meeting of stockholders, no later than July 20, 2026). However, if the date of our 2026 annual meeting of stockholders is changed by more than 30 calendar days from the anniversary date of this annual meeting, then notice must be provided by the later of 60 calendar days prior to the date of our 2026 annual meeting of stockholders and the 10th calendar day following the day on which public announcement of the date of our 2026 annual meeting of stockholders is first made.

**OTHER BUSINESS**

While the accompanying Notice of Annual Meeting of Stockholders provides for the transaction of such other business as may properly come before the meeting, we have no knowledge of any matters to be presented at the meeting other than those listed as Proposals 1, 2, 3 and 4 in the notice. However, the enclosed proxy gives discretionary authority in the event that any other matters should be presented.

**FORM 10-K**

This proxy statement is accompanied by a copy of our Annual Report on Form 10-K for the year ended December 31, 2024 (excluding exhibits). We may charge a fee equal to our reasonable expenses in furnishing the exhibits.

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| | |
|:---|:---|
|  | */s/ Lance Alstodt* |
|  | Lance Alstodt |
|  | Chief Executive Officer |
| Melville, New York |  |
| <br> August 7, 2025 |  |

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