# EDGAR Filing Document

**Accession Number:** 0001039803
**File Stem:** 0001752724-25-206189
**Filing Date:** 2025-8
**Character Count:** 20380
**Document Hash:** c32b83ef8b52b2f5531f43bdec1a528b
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001752724-25-206189.hdr.sgml**: 20250826

**ACCESSION NUMBER**: 0001752724-25-206189

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250630

**FILED AS OF DATE**: 20250826

**DATE AS OF CHANGE**: 20250826

**PERIOD START**: 20251231

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** ProFunds
- **CENTRAL INDEX KEY:** 0001039803

**ORGANIZATION NAME:**
- **EIN:** 522035197
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-08239
- **FILM NUMBER:** 251257395

**BUSINESS ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814
- **BUSINESS PHONE:** 2404976428

**MAIL ADDRESS:**
- **STREET 1:** 7272 WISCONSIN AVENUE
- **STREET 2:** 21ST FLOOR
- **CITY:** BETHESDA
- **STATE:** MD
- **ZIP:** 20814

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** PROFUNDS
- **DATE OF NAME CHANGE:** 19970521

## Series and Classes Contracts Data

### PROFUND VP PHARMACEUTICALS (Series ID: S000003975)

| Class ID   | Class Name                 | Ticker Symbol   |
|:---|:---|:---|
| C000011102 | PROFUND VP PHARMACEUTICALS |  |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** ProFunds

- **b. Investment Company Act file number:** 811-08239

- **c. CIK number of Registrant:** 0001039803

- **d. LEI of Registrant:** 549300HM4OOUYSE5DP77

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 7272 Wisconsin Avenue

  - **City:** Bethesda

  - **State:** MD

  - **Foreign country:** US

  - **Zip / Postal Code:** 20814

  - **Telephone number:** 240-497-6400

**Item A.2. Information about the Series.**

- **a. Name of Series:** PROFUND VP PHARMACEUTICALS

- **b. EDGAR series identifier (if any):** S000003975

- **c. LEI of Series:** 0NO8WMNO78H6WEYS4K25

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-12-31

- **b. Date as of which information is reported:** 2025-06-30

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $8151952.99

**Total Liabilities:** $462276.31

**Net Assets:** $7689676.68

**Cash Not Reported:** $50209.30

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000011102 | -6.02%               | -1.72%               | -0.13%               |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $210378.93               | $-693203.65                                |
| Month 2  | $-192362.82              | $50391.29                                  |
| Month 3  | $-99959.38               | $103487.56                                 |

**Designated Index Information**

- **Index Name:** Dow Jones U.S. Select Pharmaceuticals Index

- **Index Identifier:** DJSPHM

### Schedule of Portfolio Investments

| Name                                | Title                                         | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)   | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| N/A                                 | VPPH_SPSIPH_GOLDMAN                           | CUSIP: N/A<br>LEI: N/A                        | Short            | DE               |  | US        |       -34 | OU      | $883.04       | 0.01%             |  |  |  | No            |                  2 | On Loan: No      |
| Amphastar Pharmaceuticals Inc       | Amphastar Pharmaceuticals, Inc.               | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |      6329 | NS      | $145313.84    | 1.89%             |  |  |  | No            |                  1 | On Loan: No      |
| Ligand Pharmaceuticals Incorporated | Ligand Pharmaceuticals, Inc.                  | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |      1235 | NS      | $140394.80    | 1.83%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | ROYAL BANK OF CANADA  4.15 , 7/01/2025        | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |      6000 | PA      | $6000.00      | 0.08%             |  |  |  | No            |                  2 | On Loan: No      |
| Zoetis Inc.                         | Zoetis, Inc.                                  | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |      1742 | NS      | $271664.90    | 3.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Lenz Therapeutics Inc               | LENZ Therapeutics Inc                         | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      2136 | NS      | $62606.16     | 0.81%             |  |  |  | No            |                  1 | On Loan: No      |
| Elanco Animal Health Inc            | Elanco Animal Health, Inc.                    | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |     20301 | NS      | $289898.28    | 3.77%             |  |  |  | No            |                  1 | On Loan: No      |
| Amneal Pharmaceuticals Inc          | Amneal Pharmaceuticals, Inc.                  | CUSIP: 03168L105<br>LEI: 549300VV176ZO5WQHZ61 | Long             | EC               | CORP              | US        |     20701 | NS      | $167471.09    | 2.18%             |  |  |  | No            |                  1 | On Loan: No      |
| ANI Pharmaceuticals Inc.            | ANI Pharmaceuticals, Inc.                     | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |      2792 | NS      | $182178.00    | 2.37%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co.                     | Eli Lilly & Co.                               | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |       358 | NS      | $279071.74    | 3.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Viatris Inc                         | Viatris, Inc.                                 | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |     32260 | NS      | $288081.80    | 3.75%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC            | Jazz Pharmaceuticals PLC                      | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | IE        |      2622 | NS      | $278246.64    | 3.62%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc.            | Axsome Therapeutics, Inc.                     | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |      2680 | NS      | $279765.20    | 3.64%             |  |  |  | No            |                  1 | On Loan: No      |
| Innoviva Inc                        | Innoviva, Inc.                                | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |      7663 | NS      | $153949.67    | 2.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacira Biosciences Inc              | Pacira Pharmaceuticals, Inc./DE               | CUSIP: 695127100<br>LEI: 549300P56LERYBDHCF69 | Long             | EC               | CORP              | US        |      8240 | NS      | $196936.00    | 2.56%             |  |  |  | No            |                  1 | On Loan: No      |
| Prestige Consumer Healthcare Inc    | Prestige Consumer Healthcare, Inc.            | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3403 | NS      | $271729.55    | 3.53%             |  |  |  | No            |                  1 | On Loan: No      |
| Liquidia Corporation                | Liquidia Corp                                 | CUSIP: 53635D202<br>LEI: 549300O826O5VQJTG707 | Long             | EC               | CORP              | US        |      8868 | NS      | $110495.28    | 1.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc        | Xeris Biopharma Holdings Inc                  | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     31573 | NS      | $147445.91    | 1.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Supernus Pharmaceuticals, Inc       | Supernus Pharmaceuticals, Inc.                | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |      4913 | NS      | $154857.76    | 2.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Corcept Therapeutics Inc.           | Corcept Therapeutics, Inc.                    | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |      4066 | NS      | $298444.40    | 3.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc            | Enliven Therapeutics Inc                      | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      3076 | NS      | $61704.56     | 0.80%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvation Bio Inc                    | Nuvation Bio, Inc.                            | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     34575 | NS      | $67421.25     | 0.88%             |  |  |  | No            |                  1 | On Loan: No      |
| Wave Life Sciences Ltd.             | WaVe Life Sciences Ltd.                       | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | SG        |     16434 | NS      | $106821.00    | 1.39%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolus Inc                          | Evolus Inc                                    | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |      7918 | NS      | $72924.78     | 0.95%             |  |  |  | No            |                  1 | On Loan: No      |
| Arvinas Inc                         | Arvinas, Inc.                                 | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11179 | NS      | $82277.44     | 1.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocular Therapeutix Inc              | OCULAR THERAPEUTIX                            | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |     16348 | NS      | $151709.44    | 1.97%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | HSBC SECURITIES (USA), INC. B 4.3 , 7/01/2025 | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     40000 | PA      | $40000.00     | 0.52%             |  |  |  | No            |                  2 | On Loan: No      |
| Tarsus Pharmaceuticals Inc          | Tarsus Pharmaceuticals Inc                    | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      7033 | NS      | $284906.83    | 3.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Harrow Inc                          | Harrow Health, Inc.                           | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      4372 | NS      | $133520.88    | 1.74%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | UMB FINANCIAL CORP. B 4.1 , 7/01/2025         | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     14000 | PA      | $14000.00     | 0.18%             |  |  |  | No            |                  2 | On Loan: No      |
| Mind Medicine (MindMed) Inc.        | Mind Medicine MindMed Inc                     | CUSIP: 60255C885<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | CA        |      9908 | NS      | $64302.92     | 0.84%             |  |  |  | No            |                  1 | On Loan: No      |
| Collegium Pharmaceutical Inc.       | Collegium Pharmaceutical, Inc.                | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |      3917 | NS      | $115825.69    | 1.51%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc.          | Edgewise Therapeutics, Inc.                   | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     11044 | NS      | $144786.84    | 1.88%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | VPPH_SPSIPH_GOLDMAN                           | CUSIP: N/A<br>LEI: N/A                        | Long             | DE               |  | US        |        61 | OU      | $-3950.28     | -0.05%            |  |  |  | No            |                  2 | On Loan: No      |
| Royalty Pharma PLC                  | Royalty Pharma PLC                            | CUSIP: G7709Q104<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | GB        |      8508 | NS      | $306543.24    | 3.99%             |  |  |  | No            |                  1 | On Loan: No      |
| Organon & Co                        | Organon & Co.                                 | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |     28739 | NS      | $278193.52    | 3.62%             |  |  |  | No            |                  1 | On Loan: No      |
| Bristol-Myers Squibb Company        | Bristol-Myers Squibb Co.                      | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |      5775 | NS      | $267324.75    | 3.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Phibro Animal Health Corporation    | Phibro Animal Health Corp.                    | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |      2474 | NS      | $63185.96     | 0.82%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | NATWEST MARKETS PLC  4.24 , 7/01/2025         | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     11000 | PA      | $11000.00     | 0.14%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                 | SOCIETE' GENERALE  4.26 , 7/01/2025           | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     27000 | PA      | $27000.00     | 0.35%             |  |  |  | No            |                  2 | On Loan: No      |
| Perrigo Company PLC                 | Perrigo Co. PLC                               | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | IE        |     10584 | NS      | $282804.48    | 3.68%             |  |  |  | No            |                  1 | On Loan: No      |
| EyePoint Pharmaceuticals Inc.       | EyePoint Pharmaceuticals, Inc.                | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |      6374 | NS      | $59979.34     | 0.78%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings Inc    | Harmony Biosciences Holdings, Inc.            | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |      6627 | NS      | $209413.20    | 2.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Trevi Therapeutics Inc              | Trevi Therapeutics Inc                        | CUSIP: 89532M101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13386 | NS      | $73221.42     | 0.95%             |  |  |  | No            |                  1 | On Loan: No      |
| Johnson & Johnson                   | Johnson & Johnson                             | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |      1866 | NS      | $285031.50    | 3.71%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                 | CREDIT AGRICOLE CIB NY  4.26 , 7/01/2025      | CUSIP: N/A<br>LEI: N/A                        | Long             | RA               | CORP              | US        |     13000 | PA      | $13000.00     | 0.17%             |  |  |  | No            |                  2 | On Loan: No      |
| Merck & Co., Inc                    | Merck & Co., Inc.                             | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |      3607 | NS      | $285530.12    | 3.71%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc.                         | Pfizer, Inc.                                  | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |     11834 | NS      | $286856.16    | 3.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Zevra Therapeutics Inc              | Zevra Therapeutics Inc                        | CUSIP: 488445206<br>LEI: 254900CU6T74V18Y1W18 | Long             | EC               | CORP              | US        |      4184 | NS      | $36861.04     | 0.48%             |  |  |  | No            |                  1 | On Loan: No      |
| CorMedix Inc.                       | CorMedix Inc                                  | CUSIP: 21900C308<br>LEI: 5299006YIA3L0MBW8358 | Long             | EC               | CORP              | US        |      8601 | NS      | $105964.32    | 1.38%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-06-30

**Name of Applicant:** ProFund VP Pharmaceuticals

**Signature:** Rebecca Colvin

**Name of Signer:** Rebecca Colvin

**Title:** Treasurer and Principal Financial Officer