# EDGAR Filing Document

**Accession Number:** 0000855683
**File Stem:** 0001493152-26-014892
**Filing Date:** 2026-4
**Character Count:** 9858
**Document Hash:** 7d9f1ec9c0ca8ea7c47c3ea3ad857081
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0001493152-26-014892.hdr.sgml**: 20260402

**ACCESSION NUMBER**: 0001493152-26-014892

**CONFORMED SUBMISSION TYPE**: 8-K

**PUBLIC DOCUMENT COUNT**: 12

**CONFORMED PERIOD OF REPORT**: 20260331

**ITEM INFORMATION**: Entry into a Material Definitive Agreement

**ITEM INFORMATION**: Financial Statements and Exhibits

**FILED AS OF DATE**: 20260402

**DATE AS OF CHANGE**: 20260402

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** MILESTONE SCIENTIFIC INC.
- **CENTRAL INDEX KEY:** 0000855683
- **STANDARD INDUSTRIAL CLASSIFICATION:** ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
- **ORGANIZATION NAME:** 08 Industrial Applications and Services
- **EIN:** 133545623
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 1231

**FILING VALUES:**
- **FORM TYPE:** 8-K
- **SEC ACT:** 1934 Act
- **SEC FILE NUMBER:** 001-14053
- **FILM NUMBER:** 26832984

**BUSINESS ADDRESS:**
- **STREET 1:** 220 SOUTH ORANGE AVENUE
- **CITY:** LIVINGSTON
- **STATE:** NJ
- **ZIP:** 07039
- **BUSINESS PHONE:** (973) 535-2717

**MAIL ADDRESS:**
- **STREET 1:** 220 SOUTH ORANGE AVENUE
- **CITY:** LIVINGSTON
- **STATE:** NJ
- **ZIP:** 07039

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** MILESTONE SCIENTIFIC INC/NJ
- **DATE OF NAME CHANGE:** 19970409

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** U S OPPORTUNITY SEARCH INC
- **DATE OF NAME CHANGE:** 19920703

?xml version='1.0' encoding='ASCII'?

**UNITED STATES**

**SECURITIES AND EXCHANGE COMMISSION**

**Washington, D.C. 20549**

**FORM 8-K**

**CURRENT REPORT**

**Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934**

**Date of Report (Date of earliest event reported): March 31, 2026**

**Milestone Scientific Inc.**

(Exact name of registrant as specified in its charter)

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| | | |
|:---|:---|:---|
| **Delaware** | **001-14053** | **13-3545623** |
| <br> (State or other jurisdiction<br> of incorporation) | (Commission<br> File Number) | (IRS Employer<br> Identification No.) |

---

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| | |
|:---|:---|
| **425 Eagle Rock Road, Ste 403,**<br> **Roseland, New Jersey** | **07068** |
| (Address of principal executive offices) | (Zip Code) |

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Registrant's telephone number, including area code **(973) 535-2717**

**N/A**

(Former name or former address, if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instructions A.2. below):

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) Securities registered pursuant to Section 12(b) of the Act:

Title of each class Trading Symbol(s) Name on exchange on which registered <br> Common Stock MLSS NYSE American

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act ☐

**Item 1.01 — Entry into a Material Definitive Agreement**

On March 31, 2026, Milestone Scientific Inc. (the "Company") entered into an amendment (the "Amendment") to the Amended and Restated Memorandum of Understanding, dated January 13, 2026 (the "MOU"), with Innovest S.p.A., as the holder of certain consent/blockage rights with respect to BP4 S.r.l., a society' a responsibility' limitation in liquidation ("BP4"). According to BP4, it was then the owner of 11.31% of the outstanding shares of common stock of the Company

The Amendment amends the MOU to, among other things, revise the definition of "Qualified Offering" and "Other Locked-Up Parties" in order to facilitate an offering by the Company.

A copy of the Amendment is attached hereto as Exhibit 10.1 and is incorporated herein by reference.

The foregoing description of the material terms of the MOU does not purport to be complete and is qualified in its entirety by reference to such an exhibit.

**Item 9.01 — Financial Statements and Exhibits**

(d) Exhibits.

<u>Exhibit No. </u> <u>Description</u> <br> 10.1 [Amendment to Amended and Restated Memorandum of Understanding, by and between Innovest S.p.A. and Milestone Scientific Inc., dated March 31, 2026.](ex10-1.htm) <br> 104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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| | | |
|:---|:---|:---|
|  | **MILESTONE SCIENTIFIC INC.** | **MILESTONE SCIENTIFIC INC.** |
| Dated: April 2, 2026 | By: | */s/ Eric Hines* |
|  |  | Eric Hines |
|  |  | Chief Executive Officer |

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## Exhibit 10.1

**Exhibit 10.1**

MILESTONE SCIENTIFIC INC.

425 Eagle Rock Road, Ste 403,

Roseland, New Jersey 07068

As of March 31, 2026

Innovest S.p.A.

Corso Venezia 44

Milano, Italy 20121

Attn: Giandomenico Trombetta, President and Managing Director

BP4 S.r.l. in liquidazione

Corso Venezia 44 Milano

Attn: Pedro Palau, Liquidator and Legal Representative

Re: Amendment of Amended and Restated Memorandum of Understanding

Dear Sirs:

Reference is made to that certain Amended and Restated Memorandum of Understanding dated January 13, 2026 (the "**MOU**") by and between Innovest S.p.A. ("**Innovest"**), as the holder of certain consent/blockage rights with respect to BP4 S.r.l., societa' a responsabilita' limitata in liquidazione ("**BP4**"), according to BP4's corporate bylaws, in the person of Gian Domenico Trombetta as a duly authorized representative of Innovest, and Milestone Scientific Inc., a Delaware corporation (the "**Company**"). All terms used herein as defined terms but not defined herein shall have the meanings ascribed thereto in the MOU.

The purpose of this letter is to modify the MOU in certain respects, including the conditions to be satisfied for each of the BP4 Parties to enter into Lock-Up Agreements. Accordingly, the parties hereby amend the MOU, as follows:

1. In paragraph 5 of the MOU, the references to January 31, 2026
shall be changed to refer to April 17, 2026 (provided, that if the Company is then working on a capital raise that upon consummation
would be a Qualified Offering (as amended in accordance with paragraph 2 below), then such April 17, 2026 date shall automatically be
extended until May 1, 2026.

2. In Annex A of the MOU, a "Qualified Offering" shall
mean the Company's consummation of one or more offerings of its securities within forty-five (45) days from the date hereof with
aggregate gross proceeds to the Company of at least $900,000 and up to 19.99% of the number of outstanding shares of the Company (which
at the closing price of the Company's shares on March 17, 2026 of $0.29 would be approximately $2,300,000), on terms and conditions
materially similar to those terms and conditions furnished to Innovest.

3. In Annex A of the MOU, "Other Locked-Up Parties"
shall mean each of the following:

● Each of the directors of the Company re-elected at the December 18, 2025 Annual Meeting of the stockholders of the Company;

● Each of the officers of the Company; and

● United Systems and its affiliates.

Except as set forth above, the MOU shall continue in full force and effect.

In consideration of the approval, execution and delivery of this letter, the Company hereby undertakes and irrevocably commits that, within five (5) business days following the date on which both Innovest and BP4 have duly executed and returned this letter as evidence of their approval of MOU Amendments, the Company shall pay to BP4 the further amount of USD 27,500 pursuant to Article 5 of the MOU, in respect of additional disbursements accumulated in connection with the transaction contemplated by the MOU, it being understood that such payment shall be subject, together with any prior payments made pursuant to Article 5 of the MOU, to the aggregate cap of USD 100,000 expressly provided for therein.

*[Remainder of page intentionally blank]*

Innovest S.p.A. <br> page 2

Please evidence your consent to the matters set forth in this letter by signing and returning a copy of this letter.

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| | |
|:---|:---|
| Sincerely, | Sincerely, |
| Milestone Scientific Inc. | Milestone Scientific Inc. |
| By: | */s/ Eric Hines* |
| Name: | Eric Hines |
| Title: | President and Chief Executive Officer |

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**AGREED:**

The undersigned, as the holder of certain consent/blockage rights with respect to BP4 according to BP4's corporate bylaws, hereby agrees to amend the MOU as contemplated hereby.

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| | |
|:---|:---|
| Innovest S.p.A. | Innovest S.p.A. |
| By: | */s/ G D Trombetta* |
| Name: | Gian Domenico Trombetta |
| Title: | President and Managing Director |

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The undersigned, as liquidator and legal representative of BP4 S.r.l. in liquidazione, duly authorized pursuant to the resolutions adopted at the Meeting, hereby approves the MOU Amendments as set forth in this letter.

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| | |
|:---|:---|
| BP4 S.r.l. in liquidazione | BP4 S.r.l. in liquidazione |
| By: | */s/ P Palau* |
| Name: | Dottor Pedro Palau |
| Title: | iL Liquidatore and Legal Representative |

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