# EDGAR Filing Document

**Accession Number:** 0000052848
**File Stem:** 0000052848-25-000274
**Filing Date:** 2025-10
**Character Count:** 147736
**Document Hash:** fc671971421f60be3916aef550547bbb
**Contains OCR:** False
**Source Format:** 

## Filing Content

## Filing Summary
**0000052848-25-000274.hdr.sgml**: 20251028

**ACCESSION NUMBER**: 0000052848-25-000274

**CONFORMED SUBMISSION TYPE**: NPORT-P

**PUBLIC DOCUMENT COUNT**: 1

**CONFORMED PERIOD OF REPORT**: 20250831

**FILED AS OF DATE**: 20251028

**DATE AS OF CHANGE**: 20251028

**PERIOD START**: 20250831

**FILER**: 

**COMPANY DATA:**
- **COMPANY CONFORMED NAME:** VANGUARD WORLD FUND
- **CENTRAL INDEX KEY:** 0000052848

**ORGANIZATION NAME:**
- **EIN:** 046035483
- **STATE OF INCORPORATION:** DE
- **FISCAL YEAR END:** 0831

**FILING VALUES:**
- **FORM TYPE:** NPORT-P
- **SEC ACT:** 1940 Act
- **SEC FILE NUMBER:** 811-01027
- **FILM NUMBER:** 251423045

**BUSINESS ADDRESS:**
- **STREET 1:** PO BOX 2600
- **STREET 2:** V26
- **CITY:** VALLEY FORGE
- **STATE:** PA
- **ZIP:** 19482
- **BUSINESS PHONE:** 6106691000

**MAIL ADDRESS:**
- **STREET 1:** PO BOX 2600
- **STREET 2:** V26
- **CITY:** VALLEY FORGE
- **STATE:** PA
- **ZIP:** 19482

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VANGUARD WORLD FUNDS
- **DATE OF NAME CHANGE:** 20020402

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** VANGUARD WORLD FUND INC
- **DATE OF NAME CHANGE:** 19920703

**FORMER COMPANY:**
- **FORMER CONFORMED NAME:** IVEST FUND INC
- **DATE OF NAME CHANGE:** 19850923

## Series and Classes Contracts Data

### Vanguard Health Care Index Fund (Series ID: S000004450)

| Class ID   | Class Name     | Ticker Symbol   |
|:---|:---|:---|
| C000012222 | Admiral Shares | VHCIX           |
| C000012223 | ETF Shares     | VHT             |

## Form NPORT-P: Monthly Portfolio Investments Report

### NPORT-P: Part A: General Information

**Item A.1. Information about the Registrant.**

- **a. Name of Registrant:** VANGUARD WORLD FUND

- **b. Investment Company Act file number:** 811-01027

- **c. CIK number of Registrant:** 0000052848

- **d. LEI of Registrant:** 549300MP6BT0L4Q61L10

- **e. Address and telephone number of Registrant.**

  - **Street Address 1:** 100 Vanguard Boulevard

  - **City:** Malvern

  - **State:** PA

  - **Foreign country:** US

  - **Zip / Postal Code:** 19355

  - **Telephone number:** 610-669-1000

**Item A.2. Information about the Series.**

- **a. Name of Series:** VANGUARD HEALTH CARE INDEX FUND

- **b. EDGAR series identifier (if any):** S000004450

- **c. LEI of Series:** 4G9X037GNB6OUK17TK21

**Item A.3. Reporting period.**

- **a. Date of fiscal year-end:** 2025-08-31

- **b. Date as of which information is reported:** 2025-08-31

**Item A.4. Final filing**

Does the Fund anticipate that this will be its final filing on Form N-PORT? **No**

### Fund Information

**Total Assets:** $17571567687.38

**Total Liabilities:** $1687456.79

**Net Assets:** $17569880230.59

**Cash Not Reported:** $2578659.73

**Monthly Return Information**

| Class               | Month 1 Return (%)   | Month 2 Return (%)   | Month 3 Return (%)   |
|:---|:---|:---|:---|
| Class ID C000012223 | 2.29%                | -2.84%               | 5.65%                |
| Class ID C000012222 | 2.29%                | -2.84%               | 5.65%                |

**Monthly Gains & Losses**

| Period   | Net Realized Gain/Loss   | Net Unrealized Appreciation/Depreciation   |
|:---|:---|:---|
| Month 1  | $27559774.37             | $378217263.92                              |
| Month 2  | $90645665.92             | $-629375066.54                             |
| Month 3  | $57103275.63             | $766489328.03                              |

### Schedule of Portfolio Investments

| Name                                              | Title                                             | Identifiers                                   | Payoff Profile   | Asset Category   | Issuer Category   | Country   |   Balance | Units   | Value (USD)    | % of Net Assets   | Maturity Date   | Coupon Type   | Annualized Rate (%)   | Restricted?   |   Fair Value Level | Lending Status   |
|:---|:---|:---|:---|:---|:---|:---|---:|:---|:---|:---|:---|:---|:---|:---|---:|:---|
| Surgery Partners Inc                              | SURGERY PARTNERS                                  | CUSIP: 86881A100<br>LEI: 549300LC82HG33S19I03 | Long             | EC               | CORP              | US        |    231634 | NS      | $5255775.46    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Varex Imaging Corp                                | VAREX IMAGIN                                      | CUSIP: 92214X106<br>LEI: 549300CWYWPVCT8E9W67 | Long             | EC               | CORP              | US        |    124337 | NS      | $1436092.35    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Prevail Therapeutics Inc                          | PREVAIL THERAPEU - CVR                            | CUSIP: N/A<br>LEI: N/A                        | Long             | EC               | CORP              | US        |        78 | NS      | $39.00         | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Disc Medicine Inc                                 | DISC MEDICINE IN                                  | CUSIP: 254604101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     68051 | NS      | $4058901.90    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive JOHNSON&JOHNSON Pay Overnight Rate +0.65  | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    300000 | NC      | $3729000.00    | 0.02%             |  |  |  | No            |                  2 | On Loan: No      |
| Alumis Inc                                        | ALUMIS INC                                        | CUSIP: 022307102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    144857 | NS      | $672136.48     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Hologic Inc                                       | HOLOGIC INC                                       | CUSIP: 436440101<br>LEI: 549300DYP6F5ZJL0LB74 | Long             | EC               | CORP              | US        |    672709 | NS      | $45152228.08   | 0.26%             |  |  |  | No            |                  1 | On Loan: No      |
| CG oncology Inc                                   | CG ONCOLOGY INC                                   | CUSIP: 156944100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    127070 | NS      | $3408017.40    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Chemed Corp                                       | CHEMED CORP                                       | CUSIP: 16359R103<br>LEI: 54930020031IDJT2IM79 | Long             | EC               | CORP              | US        |     44265 | NS      | $20271156.75   | 0.12%             |  |  |  | No            |                  1 | On Loan: No      |
| Embecta Corp                                      | EMBECTA CORP                                      | CUSIP: 29082K105<br>LEI: 549300RPG8GXVDHNXZ62 | Long             | EC               | CORP              | US        |    167314 | NS      | $2422706.72    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Terns Pharmaceuticals Inc                         | TERNS PHARMACEUT                                  | CUSIP: 880881107<br>LEI: 254900S1ZDQMF4MYP709 | Long             | EC               | CORP              | US        |    171768 | NS      | $1195505.28    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Thermo Fisher Scientific Inc                      | THERMO FISHER                                     | CUSIP: 883556102<br>LEI: HCHV7422L5HDJZCRFL38 | Long             | EC               | CORP              | US        |   1141199 | NS      | $562291571.28  | 3.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Olema Pharmaceuticals Inc                         | OLEMA PHARMACEUT                                  | CUSIP: 68062P106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113828 | NS      | $621500.88     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Penumbra Inc                                      | PENUMBRA INC                                      | CUSIP: 70975L107<br>LEI: 549300RGE06P3ECANU72 | Long             | EC               | CORP              | US        |    111238 | NS      | $30327928.32   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Avantor Inc                                       | AVANTOR INC                                       | CUSIP: 05352A100<br>LEI: 5493003VM0XB4U8YD238 | Long             | EC               | CORP              | US        |   1900201 | NS      | $25595707.47   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Anavex Life Sciences Corp                         | ANAVEX LIFE SCIE                                  | CUSIP: 032797300<br>LEI: 549300K1I5L8COCQ8W36 | Long             | EC               | CORP              | US        |    260815 | NS      | $2514256.60    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Exelixis Inc                                      | EXELIXIS INC                                      | CUSIP: 30161Q104<br>LEI: 254900PJQB59O2O95R37 | Long             | EC               | CORP              | US        |    783494 | NS      | $29318345.48   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Mind Medicine MindMed Inc                         | MIND MEDICINE MI                                  | CUSIP: 60255C885<br>LEI: 549300QY8KN1O6RPFJ13 | Long             | EC               | CORP              | US        |    182680 | NS      | $1622198.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Option Care Health Inc                            | OPTION CARE HEAL                                  | CUSIP: 68404L201<br>LEI: 549300DI3Q5ACSYJRI17 | Long             | EC               | CORP              | US        |    495756 | NS      | $14218282.08   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| GE HealthCare Technologies Inc                    | GE HEALTHCARE TE                                  | CUSIP: 36266G107<br>LEI: 549300OI9J7XOWZMUN85 | Long             | EC               | CORP              | US        |   1384380 | NS      | $102070337.40  | 0.58%             |  |  |  | No            |                  1 | On Loan: No      |
| Zimmer Biomet Holdings Inc                        | ZIMMER BIOMET HO                                  | CUSIP: 98956P102<br>LEI: 2P2YLDVPES3BXQ1FRB91 | Long             | EC               | CORP              | US        |    598204 | NS      | $63469444.40   | 0.36%             |  |  |  | No            |                  1 | On Loan: No      |
| Kiniksa Pharmaceuticals International Plc         | KINIKSA PHARMACE                                  | CUSIP: G52694109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    102430 | NS      | $3430380.70    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Medtronic PLC                                     | MEDTRONIC PLC                                     | CUSIP: G5960L103<br>LEI: 549300GX3ZBSQWUXY261 | Long             | EC               | CORP              | US        |   3872998 | NS      | $359452944.38  | 2.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Prime Medicine Inc                                | PRIME MEDICINE I                                  | CUSIP: 74168J101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    286684 | NS      | $928856.16     | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Amicus Therapeutics Inc                           | AMICUS THERAPEUT                                  | CUSIP: 03152W109<br>LEI: 549300MRD1SMUTNBPQ53 | Long             | EC               | CORP              | US        |    743754 | NS      | $5645092.86    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Health Catalyst Inc                               | HEALTH CATALYST                                   | CUSIP: 42225T107<br>LEI: 549300223PL6GWKVJG92 | Long             | EC               | CORP              | US        |    209977 | NS      | $711822.03     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Keros Therapeutics Inc                            | KEROS THERAPEUTI                                  | CUSIP: 492327101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     85888 | NS      | $1306356.48    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Align Technology Inc                              | ALIGN TECHNOLOGY                                  | CUSIP: 016255101<br>LEI: 549300N5YSE0U3LCP840 | Long             | EC               | CORP              | US        |    207881 | NS      | $29510786.76   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Phibro Animal Health Corp                         | PHIBRO ANIMAL-A                                   | CUSIP: 71742Q106<br>LEI: 549300U24SP4AF2JUX52 | Long             | EC               | CORP              | US        |     61743 | NS      | $2288813.01    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Progyny Inc                                       | PROGYNY INC                                       | CUSIP: 74340E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    245917 | NS      | $5820855.39    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Simulations Plus Inc                              | SIMULATIONS PLUS                                  | CUSIP: 829214105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     52160 | NS      | $739107.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Haemonetics Corp                                  | HAEMONETICS CORP                                  | CUSIP: 405024100<br>LEI: 549300ZEL6TXZS6F5F95 | Long             | EC               | CORP              | US        |    145019 | NS      | $7909336.26    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| American Well Corp                                | AMERICAN WELL -A                                  | CUSIP: 03044L204<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     37869 | NS      | $261296.10     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Quest Diagnostics Inc                             | QUEST DIAGNOSTIC                                  | CUSIP: 74834L100<br>LEI: 8MCWUBXQ0WE04KMXBX50 | Long             | EC               | CORP              | US        |    337493 | NS      | $61302228.52   | 0.35%             |  |  |  | No            |                  1 | On Loan: No      |
| Innoviva Inc                                      | INNOVIVA INC                                      | CUSIP: 45781M101<br>LEI: 549300ACOX4QTBES6535 | Long             | EC               | CORP              | US        |    180539 | NS      | $3688411.77    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Celldex Therapeutics Inc                          | CELLDEX THERAPEU                                  | CUSIP: 15117B202<br>LEI: 529900F018DMYWH38923 | Long             | EC               | CORP              | US        |    179555 | NS      | $3964574.40    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Pediatrix Medical Group Inc                       | PEDIATRIX MEDICA                                  | CUSIP: 58502B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    261205 | NS      | $4495338.05    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| BioCryst Pharmaceuticals Inc                      | BIOCRYST PHARM                                    | CUSIP: 09058V103<br>LEI: 549300Z0INP1Z5NP6J59 | Long             | EC               | CORP              | US        |    598787 | NS      | $4975919.97    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Envista Holdings Corp                             | ENVISTA HOLDINGS                                  | CUSIP: 29415F104<br>LEI: 549300BX623VURJZ5269 | Long             | EC               | CORP              | US        |    511787 | NS      | $10839648.66   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Prothena Corp PLC                                 | PROTHENA CORP PL                                  | CUSIP: G72800108<br>LEI: 5299009ZXQ8NIIJ8OL30 | Long             | EC               | CORP              | US        |    130006 | NS      | $1066049.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| United Therapeutics Corp                          | UNITED THERAPEUT                                  | CUSIP: 91307C102<br>LEI: 5299005C4HZL4UWROC14 | Long             | EC               | CORP              | US        |    129569 | NS      | $39487448.44   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Savara Inc                                        | SAVARA INC                                        | CUSIP: 805111101<br>LEI: 5493002JO0WM3YMJXG33 | Long             | EC               | CORP              | US        |    208724 | NS      | $684614.72     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Amgen Inc                                         | AMGEN INC                                         | CUSIP: 031162100<br>LEI: 62QBXGPJ34PQ72Z12S66 | Long             | EC               | CORP              | US        |   1625374 | NS      | $467636353.54  | 2.66%             |  |  |  | No            |                  1 | On Loan: No      |
| Halozyme Therapeutics Inc                         | HALOZYME THERAPE                                  | CUSIP: 40637H109<br>LEI: 529900242I3SV9AGM753 | Long             | EC               | CORP              | US        |    372700 | NS      | $27263005.00   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| Perrigo Co PLC                                    | PERRIGO CO PLC                                    | CUSIP: G97822103<br>LEI: 549300IFOQS6R1QLY196 | Long             | EC               | CORP              | US        |    415052 | NS      | $9853334.48    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Axsome Therapeutics Inc                           | AXSOME THERAPEUT                                  | CUSIP: 05464T104<br>LEI: 549300EXGR0XLRJEIB95 | Long             | EC               | CORP              | US        |    104032 | NS      | $12617000.96   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunome Inc                                      | IMMUNOME INC                                      | CUSIP: 45257U108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    210775 | NS      | $2004470.25    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| AbbVie Inc                                        | ABBVIE INC                                        | CUSIP: 00287Y109<br>LEI: FR5LCKFTG8054YNNRU85 | Long             | EC               | CORP              | US        |   4489320 | NS      | $944552928.00  | 5.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Arbutus Biopharma Corp                            | ARBUTUS BIOPHARM                                  | CUSIP: 03879J100<br>LEI: 25490064CESONAUIAS23 | Long             | EC               | CORP              | US        |    431454 | NS      | $1600694.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacific Biosciences of California Inc             | PACIFIC BIOSCIEN                                  | CUSIP: 69404D108<br>LEI: 529900F1BWRE1M0KZN89 | Long             | EC               | CORP              | US        |    783564 | NS      | $1026468.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| LENZ Therapeutics Inc                             | LENZ THERAPEUTIC                                  | CUSIP: 52635N103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     34727 | NS      | $1341504.01    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ATAI Life Sciences NV                             | ATAI LIFE SCIENC                                  | CUSIP: N0731H103<br>LEI: 391200Z8UWPJSNBNCA11 | Long             | EC               | CORP              | US        |    448427 | NS      | $2053795.66    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Doximity Inc                                      | DOXIMITY INC-A                                    | CUSIP: 26622P107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    372726 | NS      | $25323004.44   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| BioLife Solutions Inc                             | BIOLIFE SOLUTION                                  | CUSIP: 09062W204<br>LEI: 549300G2IVCMC2TJDW72 | Long             | EC               | CORP              | US        |    122812 | NS      | $3076440.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Entrada Therapeutics Inc                          | ENTRADA THERAPEU                                  | CUSIP: 29384C108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     57493 | NS      | $314486.71     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cullinan Therapeutics Inc                         | CULLINAN THERAPE                                  | CUSIP: 230031106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     79582 | NS      | $600048.28     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Harmony Biosciences Holdings Inc                  | HARMONY BIOSCIE                                   | CUSIP: 413197104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    130265 | NS      | $4805475.85    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| KalVista Pharmaceuticals Inc                      | KALVISTA PHARMAC                                  | CUSIP: 483497103<br>LEI: 529900Q7IDA3WUGRZA51 | Long             | EC               | CORP              | US        |     75377 | NS      | $1014574.42    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Stryker Corp                                      | STRYKER CORP                                      | CUSIP: 863667101<br>LEI: 5493002F0SC4JTBU5137 | Long             | EC               | CORP              | US        |   1039673 | NS      | $406938408.93  | 2.32%             |  |  |  | No            |                  1 | On Loan: No      |
| Xencor Inc                                        | XENCOR INC                                        | CUSIP: 98401F105<br>LEI: 549300V5IF65437JKG30 | Long             | EC               | CORP              | US        |    181259 | NS      | $1473635.67    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Soleno Therapeutics Inc                           | SOLENO THERAPEUT                                  | CUSIP: 834203309<br>LEI: 5493003LCY77N7FXK844 | Long             | EC               | CORP              | US        |    119455 | NS      | $8083519.85    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Orthofix Medical Inc                              | ORTHOFIX MEDICAL                                  | CUSIP: 68752M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     94646 | NS      | $1417797.08    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytek Biosciences Inc                             | CYTEK BIOSCIENCE                                  | CUSIP: 23285D109<br>LEI: 549300K2J28BOC6FBO89 | Long             | EC               | CORP              | US        |    329970 | NS      | $1366075.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| MiMedx Group Inc                                  | MIMEDX GROUP INC                                  | CUSIP: 602496101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    356965 | NS      | $2534451.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| ResMed Inc                                        | RESMED INC                                        | CUSIP: 761152107<br>LEI: 529900T3QE5253CCXF22 | Long             | EC               | CORP              | US        |    443248 | NS      | $121676008.48  | 0.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Kymera Therapeutics Inc                           | KYMERA THERAPEUT                                  | CUSIP: 501575104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    127145 | NS      | $5238374.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Premier Inc                                       | PREMIER INC-CL A                                  | CUSIP: 74051N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    248705 | NS      | $6441459.50    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Sarepta Therapeutics Inc                          | SAREPTA THERAPEU                                  | CUSIP: 803607100<br>LEI: 549300IKDPIED8J8IG21 | Long             | EC               | CORP              | US        |    267009 | NS      | $4859563.80    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Surmodics Inc                                     | SURMODICS INC                                     | CUSIP: 868873100<br>LEI: 549300H76KXCAAGUS878 | Long             | EC               | CORP              | US        |     43171 | NS      | $1469540.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Waters Corp                                       | WATERS CORP                                       | CUSIP: 941848103<br>LEI: 5T547R1474YC9HOD8Q74 | Long             | EC               | CORP              | US        |    180091 | NS      | $54351463.80   | 0.31%             |  |  |  | No            |                  1 | On Loan: No      |
| TG Therapeutics Inc                               | TG THERAPEUTICS                                   | CUSIP: 88322Q108<br>LEI: 529900X21UKABN9NJ529 | Long             | EC               | CORP              | US        |    455346 | NS      | $13355298.18   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Tango Therapeutics Inc                            | TANGO THERAPEUTI                                  | CUSIP: 87583X109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    130886 | NS      | $878245.06     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ligand Pharmaceuticals Inc                        | LIGAND PHARM                                      | CUSIP: 53220K504<br>LEI: 5493008K7TB0IKP37H79 | Long             | EC               | CORP              | US        |     58244 | NS      | $9418637.24    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Apogee Therapeutics Inc                           | APOGEE THERAPEUT                                  | CUSIP: 03770N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     67302 | NS      | $2447773.74    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Coherus Oncology Inc                              | COHERUS ONCOLOGY                                  | CUSIP: 19249H103<br>LEI: 5493007IL8W5MV932D26 | Long             | EC               | CORP              | US        |    336090 | NS      | $389864.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Applied Therapeutics Inc                          | APPLIED THERAPEU                                  | CUSIP: 03828A101<br>LEI: 549300KL3IJPHZM2GR04 | Long             | EC               | CORP              | US        |    323786 | NS      | $159529.36     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Twist Bioscience Corp                             | TWIST BIOSCIENCE                                  | CUSIP: 90184D100<br>LEI: 549300T23BL59LCOH584 | Long             | EC               | CORP              | US        |    180370 | NS      | $4864578.90    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| DaVita Inc                                        | DAVITA INC                                        | CUSIP: 23918K108<br>LEI: M2XHYMU3TZNEZURC6H66 | Long             | EC               | CORP              | US        |    125403 | NS      | $17275517.28   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Solventum Corp                                    | SOLVENTUM                                         | CUSIP: 83444M101<br>LEI: 254900I70403OSGY4M28 | Long             | EC               | CORP              | US        |    471041 | NS      | $34428386.69   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| GeneDx Holdings Corp                              | GENEDX HOLDINGS                                   | CUSIP: 81663L200<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     55997 | NS      | $7251051.53    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Alignment Healthcare Inc                          | ALIGNMENT HEALTH                                  | CUSIP: 01625V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    418211 | NS      | $6841931.96    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| AdaptHealth Corp                                  | ADAPTHEALTH CORP                                  | CUSIP: 00653Q102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    285368 | NS      | $2708142.32    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Dyne Therapeutics Inc                             | DYNE THERAPEUTIC                                  | CUSIP: 26818M108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    277720 | NS      | $3746442.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Medpace Holdings Inc                              | MEDPACE HOLDINGS                                  | CUSIP: 58506Q109<br>LEI: 549300H8TYEUVTW14A54 | Long             | EC               | CORP              | US        |     73887 | NS      | $35134007.37   | 0.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Avidity Biosciences Inc                           | AVIDITY BIOSCIEN                                  | CUSIP: 05370A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    273506 | NS      | $12739909.48   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Certara Inc                                       | CERTARA INC                                       | CUSIP: 15687V109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    367363 | NS      | $3982214.92    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| OPKO Health Inc                                   | OPKO HEALTH                                       | CUSIP: 68375N103<br>LEI: 529900A4S2D4OGOJLL02 | Long             | EC               | CORP              | US        |   1317750 | NS      | $1818495.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Phreesia Inc                                      | PHREESIA INC                                      | CUSIP: 71944F106<br>LEI: 5493000HHF8NU4QOCG53 | Long             | EC               | CORP              | US        |    179648 | NS      | $5687655.68    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Korro Bio Inc                                     | KORRO BIO INC                                     | CUSIP: 500946108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     13773 | NS      | $317880.84     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Hims & Hers Health Inc                            | HIMS & HERS HEAL                                  | CUSIP: 433000106<br>LEI: 549300ZQ4ZUYSAAX6P59 | Long             | EC               | CORP              | US        |    586567 | NS      | $24841112.45   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Bristol-Myers Squibb Co                           | BRISTOL-MYER SQB                                  | CUSIP: 110122108<br>LEI: HLYYNH7UQUORYSJQCN42 | Long             | EC               | CORP              | US        |   6151869 | NS      | $290245179.42  | 1.65%             |  |  |  | No            |                  1 | On Loan: No      |
| Cigna Group/The                                   | THE CIGNA GROUP                                   | CUSIP: 125523100<br>LEI: 549300VIWYMSIGT1U456 | Long             | EC               | CORP              | US        |    807553 | NS      | $242968471.11  | 1.38%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvalent Inc                                      | NUVALENT INC-A                                    | CUSIP: 670703107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    120362 | NS      | $9217321.96    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| IQVIA Holdings Inc                                | IQVIA HOLDINGS I                                  | CUSIP: 46266C105<br>LEI: 549300W3R20NM4KQPH86 | Long             | EC               | CORP              | US        |    522258 | NS      | $99652048.98   | 0.57%             |  |  |  | No            |                  1 | On Loan: No      |
| 89bio Inc                                         | 89BIO INC                                         | CUSIP: 282559103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    330601 | NS      | $2985327.03    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| WaVe Life Sciences Ltd                            | WAVE LIFE SCIENC                                  | CUSIP: Y95308105<br>LEI: 54930070006GPKFYZ813 | Long             | EC               | CORP              | US        |    330469 | NS      | $3172502.40    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Roivant Sciences Ltd                              | ROIVANT SCIENCES                                  | CUSIP: G76279101<br>LEI: 549300DL466NY5J6U724 | Long             | EC               | CORP              | US        |    922784 | NS      | $11008813.12   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Rocket Pharmaceuticals Inc                        | ROCKET PHARMACEU                                  | CUSIP: 77313F106<br>LEI: 549300R7VV82YUIN4Y93 | Long             | EC               | CORP              | US        |    243880 | NS      | $799926.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Mural Oncology PLC                                | MURAL ONCOLOGY                                    | CUSIP: G63365103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     45854 | NS      | $94459.24      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Arrowhead Pharmaceuticals Inc                     | ARROWHEAD PHARMA                                  | CUSIP: 04280A100<br>LEI: 549300O3CSB8T7OZ3D66 | Long             | EC               | CORP              | US        |    334716 | NS      | $7373793.48    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Dianthus Therapeutics Inc                         | DIANTHUS THERAPE                                  | CUSIP: 252828108<br>LEI: 549300Z3N6ODPCOFC890 | Long             | EC               | CORP              | US        |     24614 | NS      | $580151.98     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Adaptive Biotechnologies Corp                     | ADAPTIVE BIOTECH                                  | CUSIP: 00650F109<br>LEI: 549300ZTF7OT1FW66Q96 | Long             | EC               | CORP              | US        |    321180 | NS      | $4233152.40    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Regeneron Pharmaceuticals Inc                     | REGENERON PHARM                                   | CUSIP: 75886F107<br>LEI: 549300RCBFWIRX3HYQ56 | Long             | EC               | CORP              | US        |    320898 | NS      | $186345468.60  | 1.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Bioventus Inc                                     | BIOVENTUS - A                                     | CUSIP: 09075A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    120295 | NS      | $890183.00     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Sana Biotechnology Inc                            | SANA BIOTECHNOLO                                  | CUSIP: 799566104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    409183 | NS      | $1252099.98    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Arvinas Inc                                       | ARVINAS INC                                       | CUSIP: 04335A105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    176229 | NS      | $1362250.17    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| STAAR Surgical Co                                 | STAAR SURGICAL                                    | CUSIP: 852312305<br>LEI: 5299006LRHI7OJ8BY308 | Long             | EC               | CORP              | US        |    104389 | NS      | $2856083.04    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Recursion Pharmaceuticals Inc                     | RECURSION PHAR-A                                  | CUSIP: 75629V104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    966375 | NS      | $4541962.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: —       |
| agilon health Inc                                 | AGILON HEALTH IN                                  | CUSIP: 00857U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    936003 | NS      | $1198083.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| DENTSPLY SIRONA Inc                               | DENTSPLY SIRONA                                   | CUSIP: 24906P109<br>LEI: 9NHEHR1SOZCYXDO8HO28 | Long             | EC               | CORP              | US        |    604666 | NS      | $8646723.80    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Bridgebio Pharma Inc                              | BRIDGEBIO PHARMA                                  | CUSIP: 10806X102<br>LEI: 54930028YG89VTY2J114 | Long             | EC               | CORP              | US        |    430967 | NS      | $22306851.92   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Enovis Corp                                       | ENOVIS CORP                                       | CUSIP: 194014502<br>LEI: 635400OP2DYYYMOIYL17 | Long             | EC               | CORP              | US        |    172943 | NS      | $5343938.70    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocugen Inc                                        | OCUGEN INC                                        | CUSIP: 67577C105<br>LEI: 549300JVNUI9CXWJLR09 | Long             | EC               | CORP              | US        |    876450 | NS      | $893979.00     | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Nurix Therapeutics Inc                            | NURIX THERAPEUTI                                  | CUSIP: 67080M103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    207885 | NS      | $1941645.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| HCA Healthcare Inc                                | HCA HEALTHCARE I                                  | CUSIP: 40412C101<br>LEI: 529900PH4ZGUH2MNEU89 | Long             | EC               | CORP              | US        |    545420 | NS      | $220327863.20  | 1.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Bruker Corp                                       | BRUKER CORP                                       | CUSIP: 116794108<br>LEI: LEBZ6VLQ6I8XB1NHVY15 | Long             | EC               | CORP              | US        |    320575 | NS      | $10893138.50   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| AngioDynamics Inc                                 | ANGIODYNAMICS IN                                  | CUSIP: 03475V101<br>LEI: 549300W3VKC5ZKMO8C28 | Long             | EC               | CORP              | US        |    122759 | NS      | $1259507.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| PROCEPT BioRobotics Corp                          | PROCEPT BIOROBOT                                  | CUSIP: 74276L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    167019 | NS      | $6709153.23    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| BioMarin Pharmaceutical Inc                       | BIOMARIN PHARMAC                                  | CUSIP: 09061G101<br>LEI: NSLL8ITTRR0J5HEMR848 | Long             | EC               | CORP              | US        |    580044 | NS      | $33799163.88   | 0.19%             |  |  |  | No            |                  1 | On Loan: No      |
| Amylyx Pharmaceuticals Inc                        | AMYLYX PHARMACEU                                  | CUSIP: 03237H101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    175019 | NS      | $1641678.22    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Edgewise Therapeutics Inc                         | EDGEWISE THERAPE                                  | CUSIP: 28036F105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    158820 | NS      | $2279067.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanguard Cmt Funds-Vanguard Market Liquidity Fund | Vanguard Market Liquidity Fund                    | CUSIP: N/A<br>LEI: 1I6HV0TLSTR3A4XQ6L78       | Long             | STIV             | CORP              | US        |    597728 | NS      | $59766816.22   | 0.34%             |  |  |  | No            |                  1 | On Loan: No      |
| Illumina Inc                                      | ILLUMINA INC                                      | CUSIP: 452327109<br>LEI: SQ95QG8SR5Q56LSNF682 | Long             | EC               | CORP              | US        |    478827 | NS      | $47863546.92   | 0.27%             |  |  |  | No            |                  1 | On Loan: No      |
| Aldeyra Therapeutics Inc                          | ALDEYRA THERAPEU                                  | CUSIP: 01438T106<br>LEI: 529900HGKY864E4Y9014 | Long             | EC               | CORP              | US        |    145122 | NS      | $847512.48     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Xeris Biopharma Holdings Inc                      | XERIS BIOPHARMA                                   | CUSIP: 98422E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    483673 | NS      | $3787159.59    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Biogen Inc                                        | BIOGEN INC                                        | CUSIP: 09062X103<br>LEI: W8J5WZB5IY3K0NDQT671 | Long             | EC               | CORP              | US        |    443174 | NS      | $58596466.28   | 0.33%             |  |  |  | No            |                  1 | On Loan: No      |
| Merck & Co Inc                                    | MERCK & CO                                        | CUSIP: 58933Y105<br>LEI: 4YV9Y5M8S0BRK1RP0397 | Long             | EC               | CORP              | US        |   7590407 | NS      | $638505036.84  | 3.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Ventyx Biosciences Inc                            | VENTYX BIOSCIENC                                  | CUSIP: 92332V107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    162995 | NS      | $391188.00     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ardelyx Inc                                       | ARDELYX INC                                       | CUSIP: 039697107<br>LEI: 549300F542QR4SXHCY32 | Long             | EC               | CORP              | US        |    725403 | NS      | $4613563.08    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Organon & Co                                      | ORGANON & CO                                      | CUSIP: 68622V106<br>LEI: 549300AMCKY57OK2CO56 | Long             | EC               | CORP              | US        |    785035 | NS      | $7395029.70    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| National HealthCare Corp                          | NATL HEALTHCARE                                   | CUSIP: 635906100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     39992 | NS      | $4538292.16    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| HealthEquity Inc                                  | HEALTHEQUITY INC                                  | CUSIP: 42226A107<br>LEI: 529900LRJU1RAFQHM467 | Long             | EC               | CORP              | US        |    261642 | NS      | $23372479.86   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Azenta Inc                                        | AZENTA INC                                        | CUSIP: 114340102<br>LEI: 35ZN6X1ANPH25YN32Y17 | Long             | EC               | CORP              | US        |    125438 | NS      | $3830876.52    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Theravance Biopharma Inc                          | THERAVANCE B                                      | CUSIP: G8807B106<br>LEI: 5493007VTSXP4Z6MIW52 | Long             | EC               | CORP              | US        |    114032 | NS      | $1582764.16    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Praxis Precision Medicines Inc                    | PRAXIS PRECISION                                  | CUSIP: 74006W207<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     55341 | NS      | $2520229.14    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Aura Biosciences Inc                              | AURA BIOSCIENCES                                  | CUSIP: 05153U107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    149870 | NS      | $938186.20     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Newamsterdam Pharma Co NV                         | NEWAMSTERDAM PHA                                  | CUSIP: N/A<br>LEI: 984500B6549TF6E14D36       | Long             | EC               | CORP              | US        |    135616 | NS      | $3261564.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Harrow Inc                                        | HARROW INC                                        | CUSIP: 415858109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     93991 | NS      | $3665649.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Akero Therapeutics Inc                            | AKERO THERAPEUTI                                  | CUSIP: 00973Y108<br>LEI: 549300SI3KG74LBE2955 | Long             | EC               | CORP              | US        |    169067 | NS      | $7900500.91    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Emergent BioSolutions Inc                         | EMERGENT BIOSOLU                                  | CUSIP: 29089Q105<br>LEI: 549300YW6TUOX8BE5103 | Long             | EC               | CORP              | US        |    164754 | NS      | $1367458.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Standard BioTools Inc                             | STANDARD BIOTOOL                                  | CUSIP: 34385P108<br>LEI: 549300GX8Y96GSB6YP89 | Long             | EC               | CORP              | US        |    745964 | NS      | $939914.64     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Baxter International Inc                          | BAXTER INTL INC                                   | CUSIP: 071813109<br>LEI: J5OIVXX3P24RJRW5CK77 | Long             | EC               | CORP              | US        |   1552329 | NS      | $38327003.01   | 0.22%             |  |  |  | No            |                  1 | On Loan: No      |
| Summit Therapeutics Inc                           | SUMMIT THERAPEUT                                  | CUSIP: 86627T108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    448436 | NS      | $10627933.20   | 0.06%             |  |  |  | No            |                  1 | On Loan: —       |
| RadNet Inc                                        | RADNET INC                                        | CUSIP: 750491102<br>LEI: 529900RECG94V2IZJ970 | Long             | EC               | CORP              | US        |    197564 | NS      | $14177192.64   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| GoodRx Holdings Inc                               | GOODRX HOLDIN-A                                   | CUSIP: 38246G108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    259334 | NS      | $1128102.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Sotera Health Co                                  | SOTERA HEALTH CO                                  | CUSIP: 83601L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    473701 | NS      | $7754485.37    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Agenus Inc                                        | AGENUS INC                                        | CUSIP: 00847G804<br>LEI: 529900NDQQGU5H4UJK81 | Long             | EC               | CORP              | US        |     87945 | NS      | $367610.10     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| US Physical Therapy Inc                           | US PHYSICAL THER                                  | CUSIP: 90337L108<br>LEI: 529900KL1UXQYFIOMY96 | Long             | EC               | CORP              | US        |     45894 | NS      | $3804153.66    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| MeiraGTx Holdings plc                             | MEIRAGTX HOLDING                                  | CUSIP: G59665102<br>LEI: 54930007YV6NYIOGFZ57 | Long             | EC               | CORP              | US        |    131251 | NS      | $958132.30     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| SIGA Technologies Inc                             | SIGA TECH INC                                     | CUSIP: 826917106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    130094 | NS      | $1091488.66    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Encompass Health Corp                             | ENCOMPASS HEALTH                                  | CUSIP: 29261A100<br>LEI: 549300FVRPM9DRQZRG64 | Long             | EC               | CORP              | US        |    304781 | NS      | $37110134.56   | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| OraSure Technologies Inc                          | ORASURE TECH                                      | CUSIP: 68554V108<br>LEI: 529900GNNJPNM4XHXQ77 | Long             | EC               | CORP              | US        |    208929 | NS      | $691554.99     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Protagonist Therapeutics Inc                      | PROTAGONIST THER                                  | CUSIP: 74366E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    149728 | NS      | $8841438.40    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive AVANTOR INC Pay Overnight Rate            | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    162000 | NC      | $4860.00       | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Astria Therapeutics Inc                           | ASTRIA THERAPEUT                                  | CUSIP: 04635X102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     85649 | NS      | $529310.82     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Charles River Laboratories International Inc      | CHARLES RIVER LA                                  | CUSIP: 159864107<br>LEI: 549300BSQ0R4UZ5KX287 | Long             | EC               | CORP              | US        |    148625 | NS      | $24271948.75   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Zimvie Inc                                        | ZIMVIE INC                                        | CUSIP: 98888T107<br>LEI: 549300GFKURT1J6XR665 | Long             | EC               | CORP              | US        |     84686 | NS      | $1598871.68    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| NeoGenomics Inc                                   | NEOGENOMICS INC                                   | CUSIP: 64049M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    388961 | NS      | $3415077.58    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Inspire Medical Systems Inc                       | INSPIRE MEDICAL                                   | CUSIP: 457730109<br>LEI: 549300XQQCQ7HCJKTW25 | Long             | EC               | CORP              | US        |     84577 | NS      | $7924019.13    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Butterfly Network Inc                             | BUTTERFLY NETWOR                                  | CUSIP: 124155102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    567100 | NS      | $913031.00     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Zentalis Pharmaceuticals Inc                      | ZENTALIS PHARMAC                                  | CUSIP: 98943L107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    135940 | NS      | $229738.60     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Perspective Therapeutics Inc                      | PERSPECTIVE THER                                  | CUSIP: 46489V302<br>LEI: 5493005LRKM6BCABC605 | Long             | EC               | CORP              | US        |    168245 | NS      | $565303.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Mirum Pharmaceuticals Inc                         | MIRUM PHARMACEUT                                  | CUSIP: 604749101<br>LEI: 254900YZKR40F7F27K81 | Long             | EC               | CORP              | US        |    112178 | NS      | $8286588.86    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Teleflex Inc                                      | TELEFLEX INC                                      | CUSIP: 879369106<br>LEI: UUL85LWXB4NGSWWXIQ25 | Long             | EC               | CORP              | US        |    133402 | NS      | $16863346.82   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Immunovant Inc                                    | IMMUNOVANT INC                                    | CUSIP: 45258J102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    205829 | NS      | $3023628.01    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Ultragenyx Pharmaceutical Inc                     | ULTRAGENYX PHARM                                  | CUSIP: 90400D108<br>LEI: 529900EV44GVDN1DCX77 | Long             | EC               | CORP              | US        |    256821 | NS      | $7694357.16    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Day One Biopharmaceuticals Inc                    | DAY ONE BIOPHARM                                  | CUSIP: 23954D109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    199593 | NS      | $1498943.43    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Relay Therapeutics Inc                            | RELAY THERAPEUTI                                  | CUSIP: 75943R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    358361 | NS      | $1286515.99    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Maravai LifeSciences Holdings Inc                 | MARAVAI LIFESC-A                                  | CUSIP: 56600D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    325718 | NS      | $788237.56     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Community Health Systems Inc                      | COMMUNITY HEALTH                                  | CUSIP: 203668108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    382179 | NS      | $1054814.04    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Allogene Therapeutics Inc                         | ALLOGENE THERAPE                                  | CUSIP: 019770106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    446815 | NS      | $504900.95     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| 10X Genomics Inc                                  | 10X GENOMICS I-A                                  | CUSIP: 88025U109<br>LEI: 5493003Z6741WNLG7H43 | Long             | EC               | CORP              | US        |    301916 | NS      | $4229843.16    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Erasca Inc                                        | ERASCA INC                                        | CUSIP: 29479A108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    517730 | NS      | $812836.10     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcutis Biotherapeutics Inc                       | ARCUTIS BIOTHERA                                  | CUSIP: 03969K108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    322884 | NS      | $5011159.68    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Pfizer Inc                                        | PFIZER INC                                        | CUSIP: 717081103<br>LEI: 765LHXWGK1KXCLTFYQ30 | Long             | EC               | CORP              | US        |  17186528 | NS      | $425538433.28  | 2.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Akebia Therapeutics Inc                           | AKEBIA THERAPEUT                                  | CUSIP: 00972D105<br>LEI: 549300CBQEHMKEEGNX42 | Long             | EC               | CORP              | US        |    793549 | NS      | $2491743.86    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Enhabit Inc                                       | ENHABIT INC                                       | CUSIP: 29332G102<br>LEI: 549300RFQ78SLDFSHF49 | Long             | EC               | CORP              | US        |    130463 | NS      | $1028048.44    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| LivaNova PLC                                      | LIVANOVA PLC                                      | CUSIP: G5509L101<br>LEI: 2138001K2FX6SHK2B339 | Long             | EC               | CORP              | US        |    165208 | NS      | $9312774.96    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Artivion Inc                                      | ARTIVION INC                                      | CUSIP: 228903100<br>LEI: 549300YTKV8DMSMG6K81 | Long             | EC               | CORP              | US        |    109834 | NS      | $4825007.62    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ACADIA Pharmaceuticals Inc                        | ACADIA PHARMACEU                                  | CUSIP: 004225108<br>LEI: 529900O3044NO0PEA039 | Long             | EC               | CORP              | US        |    353807 | NS      | $9195443.93    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| ANI Pharmaceuticals Inc                           | ANI PHARMACEUTIC                                  | CUSIP: 00182C103<br>LEI: 5493000T6CXTND40YH31 | Long             | EC               | CORP              | US        |     52202 | NS      | $4880887.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Ensign Group Inc/The                              | ENSIGN GROUP INC                                  | CUSIP: 29358P101<br>LEI: 5493003K4HEEA8Q0BC72 | Long             | EC               | CORP              | US        |    173866 | NS      | $29866701.48   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Mesa Laboratories Inc                             | MESA LABS                                         | CUSIP: 59064R109<br>LEI: 549300ZCG738WLX8ZW79 | Long             | EC               | CORP              | US        |     16542 | NS      | $1120720.50    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Editas Medicine Inc                               | EDITAS MEDICINE                                   | CUSIP: 28106W103<br>LEI: 5299000AON4Q9NT2JE42 | Long             | EC               | CORP              | US        |    260607 | NS      | $669759.99     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Elevance Health Inc                               | ELEVANCE HEALTH                                   | CUSIP: 036752103<br>LEI: 8MYN82XMYQH89CTMTH67 | Long             | EC               | CORP              | US        |    683003 | NS      | $217638905.95  | 1.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Revvity Inc                                       | REVVITY INC                                       | CUSIP: 714046109<br>LEI: 549300IKL1SDPFI7N655 | Long             | EC               | CORP              | US        |    355868 | NS      | $32067265.48   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanda Pharmaceuticals Inc                         | VANDA PHARMACEUT                                  | CUSIP: 921659108<br>LEI: 529900AY8VOOQBKJ0O70 | Long             | EC               | CORP              | US        |    168222 | NS      | $795690.06     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| 4D Molecular Therapeutics Inc                     | 4D MOLECULAR THE                                  | CUSIP: 35104E100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     98988 | NS      | $609766.08     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| LifeStance Health Group Inc                       | LIFESTANCE HEALT                                  | CUSIP: 53228F101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    408753 | NS      | $2239966.44    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC - 12.5                                 | CUSIP: 68218J202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22076 | NS      | $0.22          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| AnaptysBio Inc                                    | ANAPTYSBIO INC                                    | CUSIP: 032724106<br>LEI: 529900HH4WQT03IG1A12 | Long             | EC               | CORP              | US        |     44331 | NS      | $901249.23     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive JOHNSON&JOHNSON Pay Overnight Rate +0.75  | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    850000 | NC      | $10565500.00   | 0.06%             |  |  |  | No            |                  2 | On Loan: No      |
| Scholar Rock Holding Corp                         | SCHOLAR ROCK HOL                                  | CUSIP: 80706P103<br>LEI: 549300Z1FLPGL4OWJ459 | Long             | EC               | CORP              | US        |    186355 | NS      | $6084490.75    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Tarsus Pharmaceuticals Inc                        | TARSUS PHARMACEU                                  | CUSIP: 87650L103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95118 | NS      | $5572012.44    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolent Health Inc                                | EVOLENT HEALTH-A                                  | CUSIP: 30050B101<br>LEI: 549300CZOCFHQ2BBTR11 | Long             | EC               | CORP              | US        |    299826 | NS      | $2893320.90    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive ABBVIE INC Pay Overnight Rate +0.7        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    550000 | NC      | $11758994.50   | 0.07%             |  |  |  | No            |                  2 | On Loan: No      |
| Lantheus Holdings Inc                             | LANTHEUS HOLDING                                  | CUSIP: 516544103<br>LEI: 5299005HUB5IOJGO7S39 | Long             | EC               | CORP              | US        |    208858 | NS      | $11466304.20   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Amphastar Pharmaceuticals Inc                     | AMPHASTAR PHARMA                                  | CUSIP: 03209R103<br>LEI: 54930055TH0ZLSAQMJ38 | Long             | EC               | CORP              | US        |    113456 | NS      | $3474022.72    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Catalyst Pharmaceuticals Inc                      | CATALYST PHARMAC                                  | CUSIP: 14888U101<br>LEI: 5299004O0R5XXLA5H544 | Long             | EC               | CORP              | US        |    350459 | NS      | $7215950.81    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Globus Medical Inc                                | GLOBUS MEDICAL I                                  | CUSIP: 379577208<br>LEI: 5299003M2P4CIK0RF205 | Long             | EC               | CORP              | US        |    240980 | NS      | $14764844.60   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| Fate Therapeutics Inc                             | FATE THERAPEUTIC                                  | CUSIP: 31189P102<br>LEI: 549300L14Q4UHOODLA90 | Long             | EC               | CORP              | US        |    294485 | NS      | $306264.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Teladoc Health Inc                                | TELADOC HEALTH I                                  | CUSIP: 87918A105<br>LEI: 549300I2PVFBC9MFAC61 | Long             | EC               | CORP              | US        |    530279 | NS      | $4099056.67    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Replimune Group Inc                               | REPLIMUNE GROUP                                   | CUSIP: 76029N106<br>LEI: 549300AY704NEIRC4K64 | Long             | EC               | CORP              | US        |    116626 | NS      | $629780.40     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Veracyte Inc                                      | VERACYTE INC                                      | CUSIP: 92337F107<br>LEI: 529900ESWZRHXOW27Z37 | Long             | EC               | CORP              | US        |    237435 | NS      | $7203777.90    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Stoke Therapeutics Inc                            | STOKE THERAPEUTI                                  | CUSIP: 86150R107<br>LEI: 549300RD25SS2DIJHJ67 | Long             | EC               | CORP              | US        |    115442 | NS      | $2281133.92    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Henry Schein Inc                                  | HENRY SCHEIN INC                                  | CUSIP: 806407102<br>LEI: VGO3WGL8H45T73F4RR92 | Long             | EC               | CORP              | US        |    340395 | NS      | $23684684.10   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Avanos Medical Inc                                | AVANOS MEDICAL I                                  | CUSIP: 05350V106<br>LEI: 549300YCXWOM7NEWMQ58 | Long             | EC               | CORP              | US        |    140647 | NS      | $1679325.18    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Taysha Gene Therapies Inc                         | TAYSHA GENE THER                                  | CUSIP: 877619106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    513393 | NS      | $1499107.56    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Crinetics Pharmaceuticals Inc                     | CRINETICS PHARMA                                  | CUSIP: 22663K107<br>LEI: 549300Q1CNFXK5P31D28 | Long             | EC               | CORP              | US        |    268581 | NS      | $8323325.19    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Pliant Therapeutics Inc                           | PLIANT THERAPEUT                                  | CUSIP: 729139105<br>LEI: 5493002Q5LITR7VHZH02 | Long             | EC               | CORP              | US        |    146506 | NS      | $240269.84     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Incyte Corp                                       | INCYTE CORP                                       | CUSIP: 45337C102<br>LEI: 549300Z4WN6JVZ3T4680 | Long             | EC               | CORP              | US        |    497430 | NS      | $42087552.30   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| CryoPort Inc                                      | CRYOPORT                                          | CUSIP: 229050307<br>LEI: 9845004D8538BT8JF626 | Long             | EC               | CORP              | US        |    150821 | NS      | $1336274.06    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ionis Pharmaceuticals Inc                         | IONIS PHARMACEUT                                  | CUSIP: 462222100<br>LEI: 549300SI4ZGLG0BLUZ92 | Long             | EC               | CORP              | US        |    456495 | NS      | $19462664.33   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Biohaven Ltd                                      | BIOHAVEN LTD                                      | CUSIP: G1110E107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    262505 | NS      | $4039951.95    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Krystal Biotech Inc                               | KRYSTAL BIOTECH                                   | CUSIP: 501147102<br>LEI: 549300YONUY68210OE41 | Long             | EC               | CORP              | US        |     65673 | NS      | $9699902.10    | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Organogenesis Holdings Inc                        | ORGANOGENESIS HO                                  | CUSIP: 68621F102<br>LEI: 549300RLC2O821TU6941 | Long             | EC               | CORP              | US        |    177845 | NS      | $915901.75     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ceribell Inc                                      | CERIBELL INC                                      | CUSIP: 15678C102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49042 | NS      | $580166.86     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Nuvation Bio Inc                                  | NUVATION BIO INC                                  | CUSIP: 67080N101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    563062 | NS      | $1672294.14    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Neurocrine Biosciences Inc                        | NEUROCRINE BIOSC                                  | CUSIP: 64125C109<br>LEI: 549300FECER0XBN49756 | Long             | EC               | CORP              | US        |    299228 | NS      | $41772228.80   | 0.24%             |  |  |  | No            |                  1 | On Loan: No      |
| Jazz Pharmaceuticals PLC                          | JAZZ PHARMACEUTI                                  | CUSIP: G50871105<br>LEI: 635400GAUMJCLEZRRV50 | Long             | EC               | CORP              | US        |    173546 | NS      | $22170501.50   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| ARS Pharmaceuticals Inc                           | ARS PHARMACEUTIC                                  | CUSIP: 82835W108<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    133602 | NS      | $1552455.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Vanguard Cmt Funds-Vanguard Market Liquidity Fund | Vanguard Market Liquidity Fund                    | CUSIP: N/A<br>LEI: 1I6HV0TLSTR3A4XQ6L78       | Long             | STIV             | CORP              | US        | 562644024 | NS      | $562587759.20  | 3.20%             |  |  |  | No            |                  1 | On Loan: No      |
| Boston Scientific Corp                            | BOSTON SCIENTIFC                                  | CUSIP: 101137107<br>LEI: Y6ZDD9FP4P8JSSJMW954 | Long             | EC               | CORP              | US        |   4471840 | NS      | $471779120.00  | 2.69%             |  |  |  | No            |                  1 | On Loan: No      |
| Eli Lilly & Co                                    | ELI LILLY & CO                                    | CUSIP: 532457108<br>LEI: FRDRIPF3EKNDJ2CQJL29 | Long             | EC               | CORP              | US        |   2435020 | NS      | $1783846951.60 | 10.15%            |  |  |  | No            |                  1 | On Loan: No      |
| Elanco Animal Health Inc                          | ELANCO ANIMAL HE                                  | CUSIP: 28414H103<br>LEI: 549300SHPNDCE059M934 | Long             | EC               | CORP              | US        |   1500154 | NS      | $27527825.90   | 0.16%             |  |  |  | No            |                  1 | On Loan: No      |
| CRISPR Therapeutics AG                            | CRISPR THERAPEUT                                  | CUSIP: H17182108<br>LEI: 506700O6IRRIQLT3W370 | Long             | EC               | CORP              | US        |    248419 | NS      | $12875556.77   | 0.07%             |  |  |  | No            |                  1 | On Loan: —       |
| Avadel Pharmaceuticals PLC                        | AVADEL PHARMACEU                                  | CUSIP: G29687103<br>LEI: 549300E27PTSG2RHC762 | Long             | EC               | CORP              | US        |    263046 | NS      | $3882558.96    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| MaxCyte Inc                                       | MAXCYTE INC                                       | CUSIP: 57777K106<br>LEI: 54930053YHXULRFCU991 | Long             | EC               | CORP              | US        |    303889 | NS      | $422405.71     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Tempus AI Inc                                     | TEMPUS AI INC                                     | CUSIP: 88023B103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    279792 | NS      | $21225021.12   | 0.12%             |  |  |  | No            |                  1 | On Loan: —       |
| Heron Therapeutics Inc                            | HERON THERAPEUTI                                  | CUSIP: 427746102<br>LEI: 549300DR2I1DOPD2IX53 | Long             | EC               | CORP              | US        |    371134 | NS      | $501030.90     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Enliven Therapeutics Inc                          | ENLIVEN THERAPEU                                  | CUSIP: 29337E102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     98312 | NS      | $1992784.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Abbott Laboratories                               | ABBOTT LABS                                       | CUSIP: 002824100<br>LEI: HQD377W2YR662HK5JX27 | Long             | EC               | CORP              | US        |   5258961 | NS      | $697653766.26  | 3.97%             |  |  |  | No            |                  1 | On Loan: No      |
| Owens & Minor Inc                                 | OWENS & MINOR                                     | CUSIP: 690732102<br>LEI: 549300LMT5KQQXCEZ733 | Long             | EC               | CORP              | US        |    232342 | NS      | $1138475.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| QuidelOrtho Corp                                  | QUIDELORTHO CORP                                  | CUSIP: 219798105<br>LEI: 549300YU8CMO9HF53113 | Long             | EC               | CORP              | US        |    204952 | NS      | $5880072.88    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Myriad Genetics Inc                               | MYRIAD GENETICS                                   | CUSIP: 62855J104<br>LEI: 52990044IHUOUMETT163 | Long             | EC               | CORP              | US        |    276692 | NS      | $1762528.04    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Addus HomeCare Corp                               | ADDUS HOMECARE                                    | CUSIP: 006739106<br>LEI: 52990090ZT33AKPDBX62 | Long             | EC               | CORP              | US        |     55566 | NS      | $6399536.22    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| ChromaDex Corp                                    | NIAGEN BIOSCIENC                                  | CUSIP: 171077407<br>LEI: 529900OPI7B8JPXCVS70 | Long             | EC               | CORP              | US        |    169637 | NS      | $1679406.30    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| HilleVax Inc                                      | HILLEVAX INC                                      | CUSIP: 43157M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     59032 | NS      | $123376.88     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Spyre Therapeutics Inc                            | SPYRE THERAPEUTI                                  | CUSIP: 00773J202<br>LEI: 52990017AIJPRH3HQH40 | Long             | EC               | CORP              | US        |    109766 | NS      | $1810041.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| CareDx Inc                                        | CAREDX INC                                        | CUSIP: 14167L103<br>LEI: 549300NQOFKL9NON0U06 | Long             | EC               | CORP              | US        |    159584 | NS      | $2179917.44    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Rhythm Pharmaceuticals Inc                        | RHYTHM PHARMACEU                                  | CUSIP: 76243J105<br>LEI: 529900JPNWXQ8DPLA551 | Long             | EC               | CORP              | US        |    159395 | NS      | $16441594.25   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcus Biosciences Inc                             | ARCUS BIOSCIENCE                                  | CUSIP: 03969F109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    207812 | NS      | $2200729.08    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Evolus Inc                                        | EVOLUS INC                                        | CUSIP: 30052C107<br>LEI: 549300VYQRYBQOT8V419 | Long             | EC               | CORP              | US        |    144248 | NS      | $1100612.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Madrigal Pharmaceuticals Inc                      | MADRIGAL PHARMAC                                  | CUSIP: 558868105<br>LEI: 549300CHIMT2EUSNJB60 | Long             | EC               | CORP              | US        |     43569 | NS      | $19076686.65   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| CorVel Corp                                       | CORVEL CORP                                       | CUSIP: 221006109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     93398 | NS      | $8317091.90    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| uniQure NV                                        | UNIQURE NV                                        | CUSIP: N90064101<br>LEI: 724500RPCTZLFYJZ3S98 | Long             | EC               | CORP              | US        |    107485 | NS      | $1755230.05    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC                                        | CUSIP: 68218J103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    295297 | NS      | $472475.20     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive UNITEDHEALTH GRP Pay Overnight Rate +0.65 | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    165000 | NC      | $227700.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Pulse Biosciences Inc                             | PULSE BIOSCIENCE                                  | CUSIP: 74587B101<br>LEI: 529900NJUBI06118FM73 | Long             | EC               | CORP              | US        |     60930 | NS      | $946852.20     | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Collegium Pharmaceutical Inc                      | COLLEGIUM PHARMA                                  | CUSIP: 19459J104<br>LEI: 54930049FXZMTLW8D496 | Long             | EC               | CORP              | US        |     97860 | NS      | $3796968.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Tandem Diabetes Care Inc                          | TANDEM DIABETES                                   | CUSIP: 875372203<br>LEI: 549300JEPFOD0K4D3I05 | Long             | EC               | CORP              | US        |    201334 | NS      | $2518688.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Tyra Biosciences Inc                              | TYRA BIOSCIENCES                                  | CUSIP: 90240B106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     40190 | NS      | $509207.30     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Intuitive Surgical Inc                            | INTUITIVE SURGIC                                  | CUSIP: 46120E602<br>LEI: 54930052SRG011710797 | Long             | EC               | CORP              | US        |   1083408 | NS      | $512771589.36  | 2.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Dexcom Inc                                        | DEXCOM                                            | CUSIP: 252131107<br>LEI: 549300YSK3QDSFR5EU59 | Long             | EC               | CORP              | US        |   1185342 | NS      | $89303666.28   | 0.51%             |  |  |  | No            |                  1 | On Loan: No      |
| iRadimed Corp                                     | IRADIMED CORP                                     | CUSIP: 46266A109<br>LEI: 549300YVHWP0YJ1YW816 | Long             | EC               | CORP              | US        |     24935 | NS      | $1806291.40    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cytokinetics Inc                                  | CYTOKINETICS INC                                  | CUSIP: 23282W605<br>LEI: 549300BE5DY1HW7IHA64 | Long             | EC               | CORP              | US        |    342323 | NS      | $12094271.59   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| Zoetis Inc                                        | ZOETIS INC                                        | CUSIP: 98978V103<br>LEI: 549300HD9Q1LOC9KLJ48 | Long             | EC               | CORP              | US        |   1345969 | NS      | $210509551.60  | 1.20%             |  |  |  | No            |                  1 | On Loan: No      |
| PACS Group Inc                                    | PACS GROUP INC                                    | CUSIP: 69380Q107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    141119 | NS      | $1642625.16    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Iovance Biotherapeutics Inc                       | IOVANCE BIOTHERA                                  | CUSIP: 462260100<br>LEI: 2549002L8WT2ACU5Q878 | Long             | EC               | CORP              | US        |    811812 | NS      | $1810340.76    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Pulmonx Corp                                      | PULMONX CORP                                      | CUSIP: 745848101<br>LEI: 549300WZMFR0ZK7RJY40 | Long             | EC               | CORP              | US        |    110530 | NS      | $189006.30     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Prestige Consumer Healthcare Inc                  | PRESTIGE CONSUME                                  | CUSIP: 74112D101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    148641 | NS      | $10113533.64   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Alector Inc                                       | ALECTOR INC                                       | CUSIP: 014442107<br>LEI: 549300Z8RQOIY1JMHC25 | Long             | EC               | CORP              | US        |    199634 | NS      | $469139.90     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Tenet Healthcare Corp                             | TENET HEALTHCARE                                  | CUSIP: 88033G407<br>LEI: 0W9AIBT6U6ADJ2I8HK17 | Long             | EC               | CORP              | US        |    280817 | NS      | $51762997.61   | 0.29%             |  |  |  | No            |                  1 | On Loan: No      |
| Agilent Technologies Inc                          | AGILENT TECH INC                                  | CUSIP: 00846U101<br>LEI: QUIX8Y7A2WP0XRMW7G29 | Long             | EC               | CORP              | US        |    858110 | NS      | $107830102.60  | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Pennant Group Inc/The                             | PENNANT GROUP-WI                                  | CUSIP: 70805E109<br>LEI: 5493007H2OYR6BYLDA64 | Long             | EC               | CORP              | US        |    104619 | NS      | $2511902.19    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| TransMedics Group Inc                             | TRANSMEDICS GROU                                  | CUSIP: 89377M109<br>LEI: 549300060GVOSMWARH50 | Long             | EC               | CORP              | US        |     97035 | NS      | $11155143.60   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| EyePoint Pharmaceuticals Inc                      | EYEPOINT PHARMAC                                  | CUSIP: 30233G209<br>LEI: 549300QE1RU34T50MR69 | Long             | EC               | CORP              | US        |    176898 | NS      | $2046709.86    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcellx Inc                                       | ARCELLX INC                                       | CUSIP: 03940C100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     83079 | NS      | $5764851.81    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ORIC Pharmaceuticals Inc                          | ORIC PHARMACEUTI                                  | CUSIP: 68622P109<br>LEI: 54930033FJRNEYBW0L25 | Long             | EC               | CORP              | US        |    102973 | NS      | $1053413.79    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| West Pharmaceutical Services Inc                  | WEST PHARMACEUT                                   | CUSIP: 955306105<br>LEI: 5493007NKRGM1RJQ1P16 | Long             | EC               | CORP              | US        |    216890 | NS      | $53560985.50   | 0.30%             |  |  |  | No            |                  1 | On Loan: No      |
| Alkermes PLC                                      | ALKERMES PLC                                      | CUSIP: G01767105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    474554 | NS      | $13747829.38   | 0.08%             |  |  |  | No            |                  1 | On Loan: No      |
| BrightSpring Health Services Inc                  | BRIGHTSPRING HEA                                  | CUSIP: 10950A106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    293055 | NS      | $6942472.95    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| McKesson Corp                                     | MCKESSON CORP                                     | CUSIP: 58155Q103<br>LEI: 549300WZWOM80UCFSF54 | Long             | EC               | CORP              | US        |    377914 | NS      | $259490868.96  | 1.48%             |  |  |  | No            |                  1 | On Loan: No      |
| Edwards Lifesciences Corp                         | EDWARDS LIFE                                      | CUSIP: 28176E108<br>LEI: YA13X31F3V31L8TMPR58 | Long             | EC               | CORP              | US        |   1773176 | NS      | $144230135.84  | 0.82%             |  |  |  | No            |                  1 | On Loan: No      |
| Astrana Health Inc                                | ASTRANA HEALTH I                                  | CUSIP: 03763A207<br>LEI: 5493008O4R82Q4STJ936 | Long             | EC               | CORP              | US        |    135027 | NS      | $4315462.92    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Vericel Corp                                      | VERICEL CORP                                      | CUSIP: 92346J108<br>LEI: 54930076YM3PLTDR4B91 | Long             | EC               | CORP              | US        |    151637 | NS      | $5513521.32    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Treace Medical Concepts Inc                       | TREACE MEDICAL C                                  | CUSIP: 89455T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    151563 | NS      | $1112472.42    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Clover Health Investments Corp                    | CLOVER HEALTH IN                                  | CUSIP: 18914F103<br>LEI: 5493000HLYOYQU6LK133 | Long             | EC               | CORP              | US        |   1257730 | NS      | $3295252.60    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ADMA Biologics Inc                                | ADMA BIOLOGICS INC                                | CUSIP: 000899104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    720810 | NS      | $12441180.60   | 0.07%             |  |  |  | No            |                  1 | On Loan: No      |
| OmniAb Inc                                        | OMNIAB INC - 15                                   | CUSIP: 68218J301<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     22076 | NS      | $0.22          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| Geron Corp                                        | GERON CORP                                        | CUSIP: 374163103<br>LEI: 549300T282D7Z2YESL90 | Long             | EC               | CORP              | US        |   1441612 | NS      | $2018256.80    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Supernus Pharmaceuticals Inc                      | SUPERNUS PHARMAC                                  | CUSIP: 868459108<br>LEI: 549300GRM36VBKISYJ58 | Long             | EC               | CORP              | US        |    169149 | NS      | $7632002.88    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive JOHNSON&JOHNSON Pay Overnight Rate        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    100000 | NC      | $53000.00      | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| N/A                                               | Receive JOHNSON&JOHNSON Pay Overnight Rate +0.75  | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    850000 | NC      | $10565500.00   | 0.06%             |  |  |  | No            |                  2 | On Loan: No      |
| Zymeworks Inc                                     | ZYMEWORKS INC                                     | CUSIP: 98985Y108<br>LEI: 894500AHOYAGYLYZJL67 | Long             | EC               | CORP              | US        |    112546 | NS      | $1666806.26    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| SI-BONE Inc                                       | SI-BONE INC                                       | CUSIP: 825704109<br>LEI: 549300J8JGYVJJHV9C31 | Long             | EC               | CORP              | US        |    115707 | NS      | $1928835.69    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Humacyte Inc                                      | HUMACYTE INC                                      | CUSIP: 44486Q103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    373116 | NS      | $578329.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: —       |
| Molina Healthcare Inc                             | MOLINA HEALTHCAR                                  | CUSIP: 60855R100<br>LEI: 549300NQQCEQ46YHZ591 | Long             | EC               | CORP              | US        |    163623 | NS      | $29587947.09   | 0.17%             |  |  |  | No            |                  1 | On Loan: No      |
| Y-mAbs Therapeutics Inc                           | Y-MABS THERAPEUT                                  | CUSIP: 984241109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     95805 | NS      | $819132.75     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| iRhythm Technologies Inc                          | IRHYTHM TECHNOLO                                  | CUSIP: 450056106<br>LEI: 549300FJI72RJGDQS384 | Long             | EC               | CORP              | US        |     96386 | NS      | $16383692.28   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Kura Oncology Inc                                 | KURA ONCOLOGY IN                                  | CUSIP: 50127T109<br>LEI: 5493005QORQTZCZYOP39 | Long             | EC               | CORP              | US        |    209048 | NS      | $1651479.20    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| CONMED Corp                                       | CONMED CORP                                       | CUSIP: 207410101<br>LEI: Z6C0YCECH9DCU5ZIQW84 | Long             | EC               | CORP              | US        |     93547 | NS      | $5085214.92    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Vertex Pharmaceuticals Inc                        | VERTEX PHARM                                      | CUSIP: 92532F100<br>LEI: 54930015RAQRRZ5ZGJ91 | Long             | EC               | CORP              | US        |    776259 | NS      | $303532794.18  | 1.73%             |  |  |  | No            |                  1 | On Loan: No      |
| Danaher Corp                                      | DANAHER CORP                                      | CUSIP: 235851102<br>LEI: S4BKK9OTCEWQ3YHPFM11 | Long             | EC               | CORP              | US        |   1947298 | NS      | $400792874.36  | 2.28%             |  |  |  | No            |                  1 | On Loan: No      |
| Glaukos Corp                                      | GLAUKOS CORP                                      | CUSIP: 377322102<br>LEI: 5299004JA1LHE21M6T14 | Long             | EC               | CORP              | US        |    173021 | NS      | $16578872.22   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Castle Biosciences Inc                            | CASTLE BIOSCIENC                                  | CUSIP: 14843C105<br>LEI: 2549007M2Q4HLR1XD252 | Long             | EC               | CORP              | US        |     87384 | NS      | $2098089.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Cerus Corp                                        | CERUS CORP                                        | CUSIP: 157085101<br>LEI: 254900BIEY9XIDA04Q21 | Long             | EC               | CORP              | US        |    567898 | NS      | $743946.38     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| ImmunityBio Inc                                   | IMMUNITYBIO INC                                   | CUSIP: 45256X103<br>LEI: 529900J9XLBR4HFL4B83 | Long             | EC               | CORP              | US        |    799463 | NS      | $1870743.42    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Waystar Holding Corp                              | WAYSTAR HOLDING                                   | CUSIP: 946784105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    287282 | NS      | $10882242.16   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Natera Inc                                        | NATERA INC                                        | CUSIP: 632307104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    392154 | NS      | $65979910.50   | 0.38%             |  |  |  | No            |                  1 | On Loan: No      |
| AMN Healthcare Services Inc                       | AMN HEALTHCARE                                    | CUSIP: 001744101<br>LEI: 529900W3ARRTCNFH2I39 | Long             | EC               | CORP              | US        |    115728 | NS      | $2404827.84    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Quanterix Corp                                    | QUANTERIX CORP                                    | CUSIP: 74766Q101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    111373 | NS      | $506747.15     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cogent Biosciences Inc                            | COGENT BIOSCIENC                                  | CUSIP: 19240Q201<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    252535 | NS      | $3050622.80    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Royalty Pharma PLC                                | ROYALTY PHARMA-A                                  | CUSIP: G7709Q104<br>LEI: 549300FGFN7VOK8BZR03 | Long             | EC               | CORP              | US        |   1146513 | NS      | $41251537.74   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Liquidia Corp                                     | LIQUIDIA CORP                                     | CUSIP: 53635D202<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    193460 | NS      | $5354972.80    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Integer Holdings Corp                             | INTEGER HOLDINGS                                  | CUSIP: 45826H109<br>LEI: 549300SUD2ED5XG6X569 | Long             | EC               | CORP              | US        |    105347 | NS      | $11363780.89   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive JOHNSON&JOHNSON Pay Overnight Rate +0.75  | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    150000 | NC      | $1864500.00    | 0.01%             |  |  |  | No            |                  2 | On Loan: No      |
| Exact Sciences Corp                               | EXACT SCIENCES                                    | CUSIP: 30063P105<br>LEI: 549300VM3X1FYD4N9Z14 | Long             | EC               | CORP              | US        |    570548 | NS      | $27055386.16   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Brookdale Senior Living Inc                       | BROOKDALE SR                                      | CUSIP: 112463104<br>LEI: LH7MQB13NWY7CJ9VC445 | Long             | EC               | CORP              | US        |    636810 | NS      | $4903437.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| PTC Therapeutics Inc                              | PTC THERAPEUTICS                                  | CUSIP: 69366J200<br>LEI: 549300UJLWOIWFDGB318 | Long             | EC               | CORP              | US        |    215382 | NS      | $10624794.06   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| MacroGenics Inc                                   | MACROGENICS INC                                   | CUSIP: 556099109<br>LEI: 5493001KJQUA83L8MH79 | Long             | EC               | CORP              | US        |    154610 | NS      | $273659.70     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Atea Pharmaceuticals Inc                          | ATEA PHARMACEUTI                                  | CUSIP: 04683R106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    180833 | NS      | $607598.88     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| AtriCure Inc                                      | ATRICURE INC                                      | CUSIP: 04963C209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    149723 | NS      | $5538253.77    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Acadia Healthcare Co Inc                          | ACADIA HEALTHCAR                                  | CUSIP: 00404A109<br>LEI: 5493005CW985Y9D0NC11 | Long             | EC               | CORP              | US        |    278283 | NS      | $6389377.68    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Denali Therapeutics Inc                           | DENALI THERAPEUT                                  | CUSIP: 24823R105<br>LEI: 549300ZTQ2HO18L3Q830 | Long             | EC               | CORP              | US        |    416761 | NS      | $6363940.47    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Neumora Therapeutics Inc                          | NEUMORA THERAPEU                                  | CUSIP: 640979100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    170728 | NS      | $295359.44     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Apellis Pharmaceuticals Inc                       | APELLIS PHARMACE                                  | CUSIP: 03753U106<br>LEI: 254900HS0ZFRXXSB9D42 | Long             | EC               | CORP              | US        |    227731 | NS      | $6278543.67    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Establishment Labs Holdings Inc                   | ESTABLISHMENT LA                                  | CUSIP: G31249108<br>LEI: 549300BCBQ714JNJ7V58 | Long             | EC               | CORP              | US        |     52377 | NS      | $2161598.79    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Agios Pharmaceuticals Inc                         | AGIOS PHARMACEUT                                  | CUSIP: 00847X104<br>LEI: 529900ONJHY8EOGYT555 | Long             | EC               | CORP              | US        |    166145 | NS      | $6265327.95    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| IDEXX Laboratories Inc                            | IDEXX LABS                                        | CUSIP: 45168D104<br>LEI: OGMTXK0LUU1HKV2P0J84 | Long             | EC               | CORP              | US        |    243107 | NS      | $157312108.63  | 0.90%             |  |  |  | No            |                  1 | On Loan: No      |
| Bicara Therapeutics Inc                           | BICARA THERAPEUT                                  | CUSIP: 055477103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     57709 | NS      | $689045.46     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cooper Cos Inc/The                                | COOPER COS INC                                    | CUSIP: 216648501<br>LEI: QJKMVPIGLH7530PCUE20 | Long             | EC               | CORP              | US        |    602291 | NS      | $40591401.95   | 0.23%             |  |  |  | No            |                  1 | On Loan: No      |
| Vera Therapeutics Inc                             | VERA THERAPEUTIC                                  | CUSIP: 92337R101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    125133 | NS      | $2707878.12    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Privia Health Group Inc                           | PRIVIA HEALTH GR                                  | CUSIP: 74276R102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    296116 | NS      | $6822512.64    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Becton Dickinson & Co                             | BECTON DICKINSON                                  | CUSIP: 075887109<br>LEI: ICE2EP6D98PQUILVRZ91 | Long             | EC               | CORP              | US        |    866463 | NS      | $167210029.74  | 0.95%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive ABBVIE INC Pay Overnight Rate +0.7        | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    300000 | NC      | $6413997.00    | 0.04%             |  |  |  | No            |                  2 | On Loan: No      |
| Alnylam Pharmaceuticals Inc                       | ALNYLAM PHARMACE                                  | CUSIP: 02043Q107<br>LEI: 529900S3ZI14OWRJII50 | Long             | EC               | CORP              | US        |    394138 | NS      | $175986558.38  | 1.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Intellia Therapeutics Inc                         | INTELLIA THERAPE                                  | CUSIP: 45826J105<br>LEI: 5493002T5BCPE5DZC723 | Long             | EC               | CORP              | US        |    297663 | NS      | $3379963.37    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Multiplan Corp                                    | CLARITEV CORP                                     | CUSIP: 62548M209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     12401 | NS      | $854552.91     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| DocGo Inc                                         | DOCGO INC                                         | CUSIP: 256086109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    260852 | NS      | $406929.12     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Vaxcyte Inc                                       | VAXCYTE INC                                       | CUSIP: 92243G108<br>LEI: 254900M7NMHTGASX8D95 | Long             | EC               | CORP              | US        |    351239 | NS      | $10814648.81   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Novocure Ltd                                      | NOVOCURE LTD                                      | CUSIP: G6674U108<br>LEI: 213800YPP55UMHWA4826 | Long             | EC               | CORP              | US        |    319829 | NS      | $3943491.57    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| CVS Health Corp                                   | CVS HEALTH CORP                                   | CUSIP: 126650100<br>LEI: 549300EJG376EN5NQE29 | Long             | EC               | CORP              | US        |   3823871 | NS      | $279716163.65  | 1.59%             |  |  |  | No            |                  1 | On Loan: No      |
| Ideaya Biosciences Inc                            | IDEAYA BIOSCIENC                                  | CUSIP: 45166A102<br>LEI: 549300ULW08F62IJML11 | Long             | EC               | CORP              | US        |    238763 | NS      | $5861631.65    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Cassava Sciences Inc                              | CASSAVA SCIENCES                                  | CUSIP: 14817C107<br>LEI: 529900XA0UG5JXABYF08 | Long             | EC               | CORP              | US        |    132935 | NS      | $303091.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Lexicon Pharmaceuticals Inc                       | LEXICON PHARMACE                                  | CUSIP: 528872302<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    547608 | NS      | $602368.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Axogen Inc                                        | AXOGEN INC                                        | CUSIP: 05463X106<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    130617 | NS      | $2108158.38    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Corcept Therapeutics Inc                          | CORCEPT THERA                                     | CUSIP: 218352102<br>LEI: 529900EO9LUTFMZ7FF90 | Long             | EC               | CORP              | US        |    288870 | NS      | $20140016.40   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Mineralys Therapeutics Inc                        | MINERALYS THERAP                                  | CUSIP: 603170101<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    108272 | NS      | $1676050.56    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Beam Therapeutics Inc                             | BEAM THERAPEUTIC                                  | CUSIP: 07373V105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    274107 | NS      | $4484390.52    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Universal Health Services Inc                     | UNIVERSAL HLTH-B                                  | CUSIP: 913903100<br>LEI: 549300YGMGQDO0NMJD09 | Long             | EC               | CORP              | US        |    172961 | NS      | $31406258.38   | 0.18%             |  |  |  | No            |                  1 | On Loan: No      |
| Janux Therapeutics Inc                            | JANUX THERAPEUTI                                  | CUSIP: 47103J105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    116148 | NS      | $2638882.56    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Pacira BioSciences Inc                            | PACIRA BIOSCIENC                                  | CUSIP: 695127100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    140010 | NS      | $3734066.70    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| GRAIL Inc                                         | GRAIL INC                                         | CUSIP: 384747101<br>LEI: 2549009XSNESW3VE8024 | Long             | EC               | CORP              | US        |     92337 | NS      | $3027730.23    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| HealthStream Inc                                  | HEALTHSTREAM INC                                  | CUSIP: 42222N103<br>LEI: 529900OJ88H8635JNH64 | Long             | EC               | CORP              | US        |     74253 | NS      | $2085024.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Veeva Systems Inc                                 | VEEVA SYSTEMS-A                                   | CUSIP: 922475108<br>LEI: 549300YZEXPDB92M2F02 | Long             | EC               | CORP              | US        |    469320 | NS      | $126340944.00  | 0.72%             |  |  |  | No            |                  1 | On Loan: No      |
| Xenon Pharmaceuticals Inc                         | XENON PHARMACEUT                                  | CUSIP: 98420N105<br>LEI: 549300XV44Q9Z1MIPQ03 | Long             | EC               | CORP              | US        |    197288 | NS      | $7637018.48    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Centene Corp                                      | CENTENE CORP                                      | CUSIP: 15135B101<br>LEI: 549300Z7JJ4TQSQGT333 | Long             | EC               | CORP              | US        |   1504906 | NS      | $43702470.24   | 0.25%             |  |  |  | No            |                  1 | On Loan: No      |
| Altimmune Inc                                     | ALTIMMUNE INC                                     | CUSIP: 02155H200<br>LEI: 549300EOYCQ8SW3NVE64 | Long             | EC               | CORP              | US        |    247490 | NS      | $947886.70     | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Guardant Health Inc                               | GUARDANT HEALTH                                   | CUSIP: 40131M109<br>LEI: 254900M8C3E5VC8BR186 | Long             | EC               | CORP              | US        |    337411 | NS      | $22748249.62   | 0.13%             |  |  |  | No            |                  1 | On Loan: No      |
| Viridian Therapeutics Inc                         | VIRIDIAN THERAPE                                  | CUSIP: 92790C104<br>LEI: 549300C775BNYF550E70 | Long             | EC               | CORP              | US        |    172854 | NS      | $3177056.52    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Moderna Inc                                       | MODERNA INC                                       | CUSIP: 60770K107<br>LEI: 549300EI6OKH5K5Q2G38 | Long             | EC               | CORP              | US        |   1052814 | NS      | $25362289.26   | 0.14%             |  |  |  | No            |                  1 | On Loan: No      |
| Cardinal Health Inc                               | CARDINAL HEALTH                                   | CUSIP: 14149Y108<br>LEI: CCU46N3GJMF4OK4N7U60 | Long             | EC               | CORP              | US        |    721010 | NS      | $107271867.80  | 0.61%             |  |  |  | No            |                  1 | On Loan: No      |
| Viatris Inc                                       | VIATRIS INC                                       | CUSIP: 92556V106<br>LEI: 254900ZZTSW7NL773X71 | Long             | EC               | CORP              | US        |   3543047 | NS      | $37379145.85   | 0.21%             |  |  |  | No            |                  1 | On Loan: No      |
| STERIS PLC                                        | STERIS PLC                                        | CUSIP: G8473T100<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    297457 | NS      | $72894812.42   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Select Medical Holdings Corp                      | SELECT MEDICAL                                    | CUSIP: 81619Q105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    347942 | NS      | $4526725.42    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| RxSight Inc                                       | RXSIGHT INC                                       | CUSIP: 78349D107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    104447 | NS      | $944200.88     | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Mettler-Toledo International Inc                  | METTLER-TOLEDO                                    | CUSIP: 592688105<br>LEI: 5493000BD5GJNUDIUG10 | Long             | EC               | CORP              | US        |     62742 | NS      | $81629851.68   | 0.46%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Techne Corp                                   | BIO-TECHNE CORP                                   | CUSIP: 09073M104<br>LEI: 54930073RLKQ51TILZ35 | Long             | EC               | CORP              | US        |    473296 | NS      | $25856160.48   | 0.15%             |  |  |  | No            |                  1 | On Loan: No      |
| Definitive Healthcare Corp                        | DEFINITIVE HEALT                                  | CUSIP: 24477E103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    113189 | NS      | $456151.67     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Ginkgo Bioworks Holdings Inc                      | GINKGO BIOWORKS                                   | CUSIP: 37611X209<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     90009 | NS      | $1140414.03    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Ocular Therapeutix Inc                            | OCULAR THERAPEUT                                  | CUSIP: 67576A100<br>LEI: 529900ABAWFXOHSIHG03 | Long             | EC               | CORP              | US        |    312814 | NS      | $3819458.94    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Insmed Inc                                        | INSMED INC                                        | CUSIP: 457669307<br>LEI: 529900Q55QAG41CCAC11 | Long             | EC               | CORP              | US        |    574204 | NS      | $78149164.40   | 0.44%             |  |  |  | No            |                  1 | On Loan: No      |
| Humana Inc                                        | HUMANA INC                                        | CUSIP: 444859102<br>LEI: 529900YLDW34GJAO4J06 | Long             | EC               | CORP              | US        |    364858 | NS      | $110792780.28  | 0.63%             |  |  |  | No            |                  1 | On Loan: No      |
| Syndax Pharmaceuticals Inc                        | SYNDAX PHARMACEU                                  | CUSIP: 87164F105<br>LEI: 529900OF94TRHKZVBS87 | Long             | EC               | CORP              | US        |    246738 | NS      | $4029231.54    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| ALX Oncology Holdings Inc                         | ALX ONCOLOGY HOL                                  | CUSIP: 00166B105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     76537 | NS      | $89548.29      | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| MannKind Corp                                     | MANNKIND CORP                                     | CUSIP: 56400P706<br>LEI: 213800GFBCNY1ZFST722 | Long             | EC               | CORP              | US        |    873319 | NS      | $4008534.21    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Fortrea Holdings Inc                              | FORTREA HOLDINGS                                  | CUSIP: 34965K107<br>LEI: 5493000FIVFABOVCDU97 | Long             | EC               | CORP              | US        |    273184 | NS      | $2690862.40    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Gilead Sciences Inc                               | GILEAD SCIENCES                                   | CUSIP: 375558103<br>LEI: 549300WTZWR07K8MNV44 | Long             | EC               | CORP              | US        |   3760027 | NS      | $424770250.19  | 2.42%             |  |  |  | No            |                  1 | On Loan: No      |
| Travere Therapeutics Inc                          | TRAVERE THERAPEU                                  | CUSIP: 89422G107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    255120 | NS      | $4464600.00    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| ICU Medical Inc                                   | ICU MEDICAL                                       | CUSIP: 44930G107<br>LEI: 5493003NRW7LS2QZRH60 | Long             | EC               | CORP              | US        |     70843 | NS      | $9043817.38    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| UFP Technologies Inc                              | UFP TECHNOLOGIES                                  | CUSIP: 902673102<br>LEI: 549300RJ8LY41HS70C91 | Long             | EC               | CORP              | US        |     22105 | NS      | $4645586.80    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Merus NV                                          | MERUS NV                                          | CUSIP: N5749R100<br>LEI: 549300W8GPUWU8QNU293 | Long             | EC               | CORP              | US        |    157407 | NS      | $10363676.88   | 0.06%             |  |  |  | No            |                  1 | On Loan: No      |
| UnitedHealth Group Inc                            | UNITEDHEALTH GRP                                  | CUSIP: 91324P102<br>LEI: 549300GHBMY8T5GXDE41 | Long             | EC               | CORP              | US        |   2577053 | NS      | $798551413.11  | 4.55%             |  |  |  | No            |                  1 | On Loan: No      |
| Annexon Inc                                       | ANNEXON INC                                       | CUSIP: 03589W102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    211678 | NS      | $436056.68     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Concentra Group Holdings Parent Inc               | CONCENTRA GROUP                                   | CUSIP: 20603L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    348032 | NS      | $8283161.60    | 0.05%             |  |  |  | No            |                  1 | On Loan: No      |
| Talkspace Inc                                     | TALKSPACE INC                                     | CUSIP: 87427V103<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    433914 | NS      | $1154211.24    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Novavax Inc                                       | NOVAVAX INC                                       | CUSIP: 670002401<br>LEI: 529900J4GJHPEPQ23205 | Long             | EC               | CORP              | US        |    437530 | NS      | $3268349.10    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Rapport Therapeutics Inc                          | RAPPORT THERAPEU                                  | CUSIP: 75383L102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     49793 | NS      | $877850.59     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Viking Therapeutics Inc                           | VIKING THERAPEUT                                  | CUSIP: 92686J106<br>LEI: 529900IVC72YPFA25M37 | Long             | EC               | CORP              | US        |    322428 | NS      | $8721677.40    | 0.05%             |  |  |  | No            |                  1 | On Loan: —       |
| Ironwood Pharmaceuticals Inc                      | IRONWOOD PHARMAC                                  | CUSIP: 46333X108<br>LEI: 549300PC8MR6QHH6P296 | Long             | EC               | CORP              | US        |    438816 | NS      | $579237.12     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Cross Country Healthcare Inc                      | CROSS COUNTRY HE                                  | CUSIP: 227483104<br>LEI: 54930037L0NBIPZ5S663 | Long             | EC               | CORP              | US        |     88549 | NS      | $1184785.62    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| N/A                                               | Receive GLOBUS MEDICAL I Pay Overnight Rate       | CUSIP: N/A<br>LEI: N/A                        | N/A              | DE               |  | N/A       |    100000 | NC      | $864000.00     | 0.00%             |  |  |  | No            |                  2 | On Loan: No      |
| Repligen Corp                                     | REPLIGEN CORP                                     | CUSIP: 759916109<br>LEI: 54930006QJ0T5AUO1E71 | Long             | EC               | CORP              | US        |    161547 | NS      | $19760429.04   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Lyell Immunopharma Inc                            | LYELL IMMUNOPHAR                                  | CUSIP: 55083R203<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     15946 | NS      | $176681.68     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| Aurinia Pharmaceuticals Inc                       | AURINIA PHARMACE                                  | CUSIP: 05156V102<br>LEI: 5299008YP2BW4570ML28 | Long             | EC               | CORP              | US        |    346870 | NS      | $4158971.30    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| LeMaitre Vascular Inc                             | LEMAITRE VASCULA                                  | CUSIP: 525558201<br>LEI: 549300FZUBUB7MHY8R17 | Long             | EC               | CORP              | US        |     64811 | NS      | $6180701.02    | 0.04%             |  |  |  | No            |                  1 | On Loan: No      |
| Neogen Corp                                       | NEOGEN CORP                                       | CUSIP: 640491106<br>LEI: 549300HJT9FC36N4UW43 | Long             | EC               | CORP              | US        |    623789 | NS      | $3586786.75    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Alphatec Holdings Inc                             | ALPHATEC HOLDING                                  | CUSIP: 02081G201<br>LEI: 549300EZE8CQ8K65FS24 | Long             | EC               | CORP              | US        |    353055 | NS      | $5613574.50    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| Cencora Inc                                       | CENCORA INC                                       | CUSIP: 03073E105<br>LEI: AI8GXW8LG5WK7E9UD086 | Long             | EC               | CORP              | US        |    556580 | NS      | $162304293.80  | 0.92%             |  |  |  | No            |                  1 | On Loan: No      |
| Insulet Corp                                      | INSULET CORP                                      | CUSIP: 45784P101<br>LEI: 549300TZTYD2PYN92D43 | Long             | EC               | CORP              | US        |    212751 | NS      | $72309809.88   | 0.41%             |  |  |  | No            |                  1 | On Loan: No      |
| Vir Biotechnology Inc                             | VIR BIOTECHNOLOG                                  | CUSIP: 92764N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    270335 | NS      | $1335454.90    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Johnson & Johnson                                 | JOHNSON&JOHNSON                                   | CUSIP: 478160104<br>LEI: 549300G0CFPGEF6X2043 | Long             | EC               | CORP              | US        |   5022852 | NS      | $889898688.84  | 5.06%             |  |  |  | No            |                  1 | On Loan: No      |
| Merit Medical Systems Inc                         | MERIT MEDICAL                                     | CUSIP: 589889104<br>LEI: 549300OYTY138SP2CE83 | Long             | EC               | CORP              | US        |    178632 | NS      | $16173341.28   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Bio-Rad Laboratories Inc                          | BIO-RAD LABS-A                                    | CUSIP: 090572207<br>LEI: 549300ZC1GPV35XYDK53 | Long             | EC               | CORP              | US        |     56819 | NS      | $16925243.72   | 0.10%             |  |  |  | No            |                  1 | On Loan: No      |
| Integra LifeSciences Holdings Corp                | INTEGRA LIFESCIE                                  | CUSIP: 457985208<br>LEI: WB7IJCYY8YFTENS4O147 | Long             | EC               | CORP              | US        |    199378 | NS      | $3016589.14    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| OrthoPediatrics Corp                              | ORTHOPEDIATRICS                                   | CUSIP: 68752L100<br>LEI: 5493000KUTPFGOPAT717 | Long             | EC               | CORP              | US        |     47875 | NS      | $1022610.00    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Schrodinger Inc/United States                     | SCHRODINGER INC                                   | CUSIP: 80810D103<br>LEI: 984500044BAE4791E559 | Long             | EC               | CORP              | US        |    194539 | NS      | $3795455.89    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Monte Rosa Therapeutics Inc                       | MONTE ROSA THERA                                  | CUSIP: 61225M102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    111401 | NS      | $534724.80     | 0.00%             |  |  |  | No            |                  1 | On Loan: No      |
| MoonLake Immunotherapeutics                       | MOONLAKE IMMUNOT                                  | CUSIP: 61559X104<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     67588 | NS      | $3768031.00    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Arcturus Therapeutics Holdings Inc                | ARCTURUS THERAPE                                  | CUSIP: 03969T109<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     73713 | NS      | $1253858.13    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Amneal Pharmaceuticals Inc                        | AMNEAL PHARM INC                                  | CUSIP: 03168L105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    474603 | NS      | $4537204.68    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |
| REGENXBIO Inc                                     | REGENXBIO INC                                     | CUSIP: 75901B107<br>LEI: 549300EOES47LATSET33 | Long             | EC               | CORP              | US        |    127615 | NS      | $1139601.95    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Phathom Pharmaceuticals Inc                       | PHATHOM PHARMACE                                  | CUSIP: 71722W107<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    126563 | NS      | $1541537.34    | 0.01%             |  |  |  | No            |                  1 | On Loan: —       |
| Chinook Therapeutics Inc                          | CHINOOK THERAPEUTICS INC - CVR (AUG 2023)         | CUSIP: N/A<br>LEI: 549300X0O3003W5QYQ48       | Long             | EC               | CORP              | US        |       784 | NS      | $0.00          | 0.00%             |  |  |  | No            |                  3 | On Loan: No      |
| ArriVent Biopharma Inc                            | ARRIVENT BIOPHAR                                  | CUSIP: 04272N102<br>LEI: N/A                  | Long             | EC               | CORP              | US        |     55417 | NS      | $1059573.04    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Fulgent Genetics Inc                              | FULGENT GENETICS                                  | CUSIP: 359664109<br>LEI: 549300CL6P01M68QJ404 | Long             | EC               | CORP              | US        |     59681 | NS      | $1323127.77    | 0.01%             |  |  |  | No            |                  1 | On Loan: No      |
| Masimo Corp                                       | MASIMO CORP                                       | CUSIP: 574795100<br>LEI: 549300Q4A8JK0PIYCU29 | Long             | EC               | CORP              | US        |    139485 | NS      | $19487449.35   | 0.11%             |  |  |  | No            |                  1 | On Loan: No      |
| Dynavax Technologies Corp                         | DYNAVAX TECHNOLO                                  | CUSIP: 268158201<br>LEI: 549300T5URIXWDILX594 | Long             | EC               | CORP              | US        |    290298 | NS      | $2937815.76    | 0.02%             |  |  |  | No            |                  1 | On Loan: No      |
| Labcorp Holdings Inc                              | LABCORP HOLDINGS                                  | CUSIP: 504922105<br>LEI: N/A                  | Long             | EC               | CORP              | US        |    253060 | NS      | $70348149.40   | 0.40%             |  |  |  | No            |                  1 | On Loan: No      |
| REVOLUTION Medicines Inc                          | REVOLUTION MEDIC                                  | CUSIP: 76155X100<br>LEI: 549300JU3X0LBCQ65892 | Long             | EC               | CORP              | US        |    422259 | NS      | $16033174.23   | 0.09%             |  |  |  | No            |                  1 | On Loan: No      |
| Tilray Brands Inc                                 | TILRAY BRANDS IN                                  | CUSIP: 88688T100<br>LEI: 549300Y4V60733TO1478 | Long             | EC               | CORP              | US        |   3133675 | NS      | $4324471.50    | 0.02%             |  |  |  | No            |                  1 | On Loan: —       |
| Omnicell Inc                                      | OMNICELL INC                                      | CUSIP: 68213N109<br>LEI: 5493008RH0GTKHHPZI77 | Long             | EC               | CORP              | US        |    141783 | NS      | $4620707.97    | 0.03%             |  |  |  | No            |                  1 | On Loan: No      |

### Signature

**Date Signed:** 2025-10-28

**Name of Applicant:** VANGUARD WORLD FUND

**Signature:** Ashley Grim

**Name of Signer:** Ashley Grim

**Title:** Treasurer