LEME
Collection
5 items • Updated
Datasets:
patient_id stringlengths 3 6 | patient_uid stringlengths 9 11 | PMID stringlengths 8 8 | file_path stringlengths 35 39 | title stringlengths 13 255 | patient stringlengths 116 16.7k | gender stringclasses 2
values | pub_date stringclasses 970
values | age_json stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|
143 | 1156905-1 | 15916712 | oa_comm/PMC001xxxxxx/PMC1156905.xml | Primary graft failure associated with epithelial downgrowth: a case report | A 59 year-old male with Fuchs' endothelial dystrophy presented with visually limiting pseudophakic corneal edema in his right eye with a best-corrected visual acuity of 20/50. Cataract extraction had been performed two years previously in the right eye through a 3.2 mm limbal incision. An uncomplicated penetrating kera... | M | 2005 | [[59.0, "year"]] |
153 | 1166562-1 | 15967041 | oa_comm/PMC001xxxxxx/PMC1166562.xml | Annular pigment band on the posterior capsule following blunt ocular trauma: a case report | A 28-year-old male presented with a dull ache and photophobia in the right eye following blunt ocular trauma. Three days earlier he had been hit in the right eye with a cricket ball. There were no other ocular complaints or significant past ocular history. The patient was in excellent general health and was not taking ... | M | 2005 | [[28.0, "year"]] |
195 | 1200253-1 | 16105181 | oa_comm/PMC001xxxxxx/PMC1200253.xml | Is Microsporidial keratitis an emerging cause of stromal keratitis? – a case series study | A 40-year-old lady presented to our institute with recurrent pain, redness, watering and blurred vision of seven months duration. During this time she had received topical steroids, antiviral and antifungal medications. However, there was no resolution in the signs or symptoms. The treating surgeon felt she was worseni... | F | 2005 | [[40.0, "year"]] |
196 | 1200253-2 | 16105181 | oa_comm/PMC001xxxxxx/PMC1200253.xml | Is Microsporidial keratitis an emerging cause of stromal keratitis? – a case series study | Parents of a 2-year-old male child brought him with complaints of white spot on the black of the left eye and swelling of the lids since one and half months. The child had red eye three months back which subsided with eyedrops (Ofloxacin and Tobramycin) but the opacity persisted. Vision could not be assessed as he was ... | M | 2005 | [[2.0, "year"]] |
197 | 1200253-3 | 16105181 | oa_comm/PMC001xxxxxx/PMC1200253.xml | Is Microsporidial keratitis an emerging cause of stromal keratitis? – a case series study | A 70-year old female presented with complaints of pain, redness, watering and diminution of vision in the left eye of one month duration. She gave history of injury with grass six months ago. Visual acuity in right eye was 6/12 and hand movements with counting finger in the left eye. Right eye on examination was within... | F | 2005 | [[70.0, "year"]] |
198 | 1200253-4 | 16105181 | oa_comm/PMC001xxxxxx/PMC1200253.xml | Is Microsporidial keratitis an emerging cause of stromal keratitis? – a case series study | A 37-year-old male presented with history of injury in left eye during a fight years ago. His vision decreased but he did not use any medications. On examination, vision in right eye was 6/6 and in the left eye it was PL positive, PR accurate. Right eye examination was within normal limits. Left eye showed trace conjun... | M | 2005 | [[37.0, "year"]] |
203 | 1208903-1 | 16105182 | oa_comm/PMC001xxxxxx/PMC1208903.xml | Bilateral neuro-retinitis following chick embryo cell anti-rabies vaccination – a case report | A 56 year old male presented with complaint of acute onset painless diminution of vision in the right eye of 3 days duration followed by similar complaint in left eye after 1 day which deteriorated over the next 2 days. This was associated with headache and pain on ocular movements. There was a history of being bitten ... | M | 2005 | [[56.0, "year"]] |
245 | 1262727-1 | 16202173 | oa_comm/PMC001xxxxxx/PMC1262727.xml | Citalopram associated with acute angle-closure glaucoma: case report | We describe the case of a 54 year old, non-smoker, Caucasian woman, a computer programmer, who was admitted to the General Hospital in June 2003, following an episode of overdose with Citalopram and alcohol. At the time of her admission, she gave a history of depression and suicidal ideation for six months. She was not... | F | 2005 | [[54.0, "year"]] |
318 | 1388244-1 | 16409642 | oa_comm/PMC001xxxxxx/PMC1388244.xml | Refractile superficial retinal crystals and chronic retinal detachment: Case report | A 45-year-old man with a history of non-insulin dependant diabetes for two years attended for digital fundal photography for diabetic retinopathy screening. He was asymptomatic with 6/6 unaided vision bilaterally. Examination of the photographs on the right showed multiple refractile glistening opacities at the macula,... | M | 2006 | [[45.0, "year"]] |
319 | 1388244-2 | 16409642 | oa_comm/PMC001xxxxxx/PMC1388244.xml | Refractile superficial retinal crystals and chronic retinal detachment: Case report | A 25-year-old man was referred by his optician, who had noted an abnormal left macular appearance during a routine check-up. He was asymptomatic and achieved unaided vision of 6/6 bilaterally. On examination, the left macula showed scattered superficial refractile deposits at the retinal surface. There was also an infe... | M | 2006 | [[25.0, "year"]] |
337 | 1403799-1 | 16507105 | oa_comm/PMC001xxxxxx/PMC1403799.xml | Ultrasound biomicroscopy findings of 25 G Transconjuctival sutureless (TSV) and conventional (20G) pars plana sclerotomy in the same patient | A 25 year old male patient was admitted with a diagnosis of Eales' disease and a non-resolving vitreous hemorrhage involving the left eye of 2 months duration. Ultrasound evaluation of the posterior segment revealed findings consistent with an organized vitreous hemorrhage and incomplete posterior vitreous detachment. ... | M | 2006 | [[25.0, "year"]] |
438 | 1526752-1 | 16827934 | oa_comm/PMC001xxxxxx/PMC1526752.xml | Bilateral acute angle closure glaucoma as a presentation of isolated microspherophakia in an adult: case report | A 45-year-old Nepalese woman presented with acute pain and decreased vision in both eyes since two months. She had a history of treatment with oral acetazolamide, 4% pilocarpine drops and underwent laser iridotomy in the left eye. There was no previous history of such episodes. At presentation (Fig. , Top), both eyes h... | F | 2006 | [[45.0, "year"]] |
544 | 1592121-1 | 16995931 | oa_comm/PMC001xxxxxx/PMC1592121.xml | Acute red eye and back pain as a presentation for systemic illness: case report | A 73-year old lady was referred to the Ophthalmic Accident and Emergency Department with a five-day history of decreased visual acquity and floaters in the vision of her left eye. The patient had no previous medical or ophthalmic history and had been well over the preceding weeks, other than a treated urinary tract inf... | F | 2006 | [[73.0, "year"]] |
575 | 1624848-1 | 17034630 | oa_comm/PMC001xxxxxx/PMC1624848.xml | Bilateral ischemic optic neuropathy after transurethral prostatic resection: a case report | A 66-year old man underwent elective TPR for benign prostatic hyperplasia. The preoperative blood pressure was 140/85 mmHg, hemoglobin 15.9 g/dL, and hematocrit 48.6%. Surgery was performed with glycine irrigation. Two hours after surgery, the blood pressure was 85/40 mm Hg, hemoglobin 7.2 g/dL, and hematocrit 22.3% (f... | M | 2006 | [[66.0, "year"]] |
740 | 1838406-1 | 17362519 | oa_comm/PMC001xxxxxx/PMC1838406.xml | Painful vertical diplopia as a presentation of a pituitary mass | A 47 year old female who was otherwise healthy presented with a sudden onset vertical diplopia associated with right sided headache and right eye pain. On examination she had a right hypotropia measuring 20^ for distance. Eye movements were limited in dextroelevation with associated discomfort. Ocular motility testing ... | F | 2007 | [[47.0, "year"]] |
781 | 1855313-1 | 17411428 | oa_comm/PMC001xxxxxx/PMC1855313.xml | Radiation Retinopathy: Case report and review | A 55 year old male was referred from the oncology department with epiphora. His medical history included type 2, Insulin treated, Diabetes Mellitus of 10-years duration and controlled hypertension. He smoked between 20–40 cigarettes per day. One year prior to presentation he had undergone a total rhinectomy with a 4 we... | M | 2007 | [[55.0, "year"]] |
789 | 1863413-1 | 17439660 | oa_comm/PMC001xxxxxx/PMC1863413.xml | Unilateral external ophthalmoplegia in Miller Fisher syndrome: case report | A 32-year old gentleman presented to the ophthalmic accident and emergency department with a four-day history of worsening horizontal and vertical diplopia. He denied any other ophthalmic or neurological symptoms at presentation. Other than a recent mild coryzal illness he was fit and well. He had no significant past o... | M | 2007 | [[32.0, "year"]] |
813 | 1876204-1 | 17462097 | oa_comm/PMC001xxxxxx/PMC1876204.xml | Thiazolidinedione induced thyroid associated orbitopathy | In February 2005, a 56-year-old female smoker presented to our clinic for follow-up of her Graves' disease. Eyelid retraction was noted two years prior to presentation, but she reported no proptosis or other signs of TAO. She was diagnosed with hyperthyroidism in August 2004 and had been stabilized on propranolol and p... | F | 2007 | [[56.0, "year"]] |
1331 | 2268858-1 | 18334962 | oa_comm/PMC002xxxxxx/PMC2268858.xml | Presence of myocilin sequence variants in Japanese patients with open-angle glaucoma | Case 1 was a 71-year-old man diagnosed with POAG at the age of 60 years. He has three brothers and four sisters, but none of them has a glaucoma history. His IOP at the time of diagnosis was 28 mmHg Oculus Dexter (OD), and 45 mmHg Oculus Sinister (OD). He underwent trabeculectomy in his left eye in 2002. In 2007, his b... | M | 2008 | [[71.0, "year"]] |
1332 | 2268858-2 | 18334962 | oa_comm/PMC002xxxxxx/PMC2268858.xml | Presence of myocilin sequence variants in Japanese patients with open-angle glaucoma | Case 2 was a 60-year-old woman who was diagnosed with POAG in 1970 at the age of 24 years (). She underwent trabeculectomy four times in her right eye and twice in her left eye from 1980 to 1981. In 1993, the visual acuity of her right eye and left eye was hand motion and counting finger, respectively. The optic discs ... | F | 2008 | [[60.0, "year"]] |
1333 | 2268858-3 | 18334962 | oa_comm/PMC002xxxxxx/PMC2268858.xml | Presence of myocilin sequence variants in Japanese patients with open-angle glaucoma | This patient was a 65-year-old woman diagnosed with POAG at the age of 44 years. Her brother had also been diagnosed with glaucoma () at the age of 48. As for her mother, no medical record was available regarding the age at diagnosis.
Her IOP at the time of diagnosis was 22–24 mmHg in both eyes. Her BCVA was 20/20 OU. ... | F | 2008 | [[65.0, "year"]] |
1459 | 2373796-1 | 18470323 | oa_comm/PMC002xxxxxx/PMC2373796.xml | Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene | The proband had a history of recurrent corneal erosions in both eyes, which began when he was four years old. Slit lamp examination showed the presence of large, typical fine branching lattice lines in the anterior stroma in OD (). A clear area was preserved around the corneal-scleral limbus. Best-corrected vision was ... | M | 2008 | [[4.0, "year"]] |
1716 | 2483297-1 | 18660851 | oa_comm/PMC002xxxxxx/PMC2483297.xml | Familial Wolfram syndrome due to compound heterozygosity for two novel WFS1 mutations | This was a 19-year-old male, the oldest of the four brothers, who was given a diagnosis of diabetes mellitus type 1 when he was 10 years old. He came to our hospital complaining of decreased vision. At examination, his visual acuity was 20/400 that improved after refraction to 20/300 in the right eye, and 3/200 that im... | M | 2008 | [[19.0, "year"]] |
1717 | 2483297-2 | 18660851 | oa_comm/PMC002xxxxxx/PMC2483297.xml | Familial Wolfram syndrome due to compound heterozygosity for two novel WFS1 mutations | This was a 16-year-old male, who received a diagnosis of diabetes mellitus type 1 when he was 6 years old. He complained of having decreased vision for several years. On examination, his visual acuity was count fingers at 15 cm in the right eye that did not improve and hand movement in the left eye that did not improve... | M | 2008 | [[16.0, "year"]] |
1718 | 2483297-3 | 18660851 | oa_comm/PMC002xxxxxx/PMC2483297.xml | Familial Wolfram syndrome due to compound heterozygosity for two novel WFS1 mutations | This was a 14-year-old male, who was given a diagnosis of diabetes mellitus type 1 when he was 7 years old. He had a history of a surgical correction of a tracheoesophagic fistula at the age of 8 months. He presented with a history of decreased visual acuity. At ophthalmologic examination, his visual acuity was 20/100 ... | M | 2008 | [[14.0, "year"]] |
1719 | 2483297-4 | 18660851 | oa_comm/PMC002xxxxxx/PMC2483297.xml | Familial Wolfram syndrome due to compound heterozygosity for two novel WFS1 mutations | The youngest brother was 11 years old. He received a diagnosis of diabetes mellitus type 1 when he was 5 years old. In the right eye, he had a visual acuity of 20/300 that improved to 20/200, and in the left eye, it was 20/400 that improved to 20/300. Pupils were mydriatic with decreased light reflex. Both optic nerve ... | M | 2008 | [[11.0, "year"]] |
1913 | 2533035-1 | 17293779 | oa_comm/PMC002xxxxxx/PMC2533035.xml | Variation in optineurin (OPTN) allele frequencies between and within populations | Case 1, a 52 year old Chilean female (III:1; ), was diagnosed with NTG at age 42 years and her highest pretreatment IOP was 18 mmHg in both eyes. After bilateral trabeculectomies and betaxolol treatment, her IOPs were 6 mmHg in the right eye and 10 mmHg in the left eye. Gonioscopic exam revealed open angles in both eye... | F | 2007 | [[52.0, "year"]] |
2319 | 2605696-1 | 19478861 | oa_comm/PMC002xxxxxx/PMC2605696.xml | Linear Basal Cell Carcinoma in an Asian Patient | An 87 year-old woman presented with an ulcerated black nodule, 15 x 5 mm (3: 1), on nasojugal fold of the right lower eyelid (Fig. ). Her lower eyelid was everted toward the tumour because of the traction and the lateral margin of the tumour was situated to around the half of the lower eyelid. Computed tomography did n... | F | 2007-12-17 | [[87.0, "year"]] |
2854 | 2669507-1 | 17515881 | oa_comm/PMC002xxxxxx/PMC2669507.xml | Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisis | A c.574C>T mutation was found in a 10-year-old male. His best corrected visual acuity (BCVA) was OD: 6/18, OS: 6/60. He had foveal schisis in his the right eye, and peripheral schisis in both eyes. There was a full-thickness macular hole in his left eye. The clinical findings of this patient have been previously report... | M | 2007 | [[10.0, "year"]] |
2855 | 2669507-2 | 17515881 | oa_comm/PMC002xxxxxx/PMC2669507.xml | Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisis | A c.583A>G variation was identified in an 11-year-old male. His BCVA was OD: 6/60, OS: 6/60. Clinical features associated with this mutation were foveal and a temporal peripheral schisis observed bilaterally. He had rhegmatogenous retinal detachment (RRD) in both eyes, although confined to the temporal schisis. To the ... | M | 2007 | [[11.0, "year"]] |
2856 | 2669507-3 | 17515881 | oa_comm/PMC002xxxxxx/PMC2669507.xml | Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisis | A c.608C>T mutation was observed in a 20-year-old male. His BCVA was OD: 6/18, OS: 6/18. He had bilateral foveal schisis, with normal periphery. | M | 2007 | [[20.0, "year"]] |
2857 | 2669507-4 | 17515881 | oa_comm/PMC002xxxxxx/PMC2669507.xml | Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisis | A c.617G>A nonsense mutation was found in a 10-year-old male. His BCVA was OD: 5/60, OS: 6/60. He had foveal and peripheral schisis in both eyes. His ERG findings showed suppression of a and b-waves in his right eye, although b-wave amplitude was depressed to a greater extent. He had total RRD in his right eye (). Surg... | M | 2007 | [[10.0, "year"]] |
2858 | 2669507-5 | 17515881 | oa_comm/PMC002xxxxxx/PMC2669507.xml | Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisis | A c.637C>T transition was observed in a 17-year-old male. His BCVA was OD: 6/6, OS: 6/36. He has foveal schisis in his right eye, and peripheral schisis in both eyes (). He demonstrated a spontaneously settled inferotemporal RRD involving the left macula, with consequent foveal atrophy (). His right eye showed evidence... | M | 2007 | [[17.0, "year"]] |
2859 | 2669507-6 | 17515881 | oa_comm/PMC002xxxxxx/PMC2669507.xml | Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisis | A c.637C>T transition mutation was also identified in patient 6, a 30-year-old male. His BCVA was OD: 6/24, OS: 6/36. He had foveal and peripheral schisis in both eyes. He developed a vitreous hemorrhage (due to avulsion of floating vessels) in his left eye, which settled spontaneously over two months. | M | 2007 | [[30.0, "year"]] |
2887 | 2683430-1 | 19384018 | oa_comm/PMC002xxxxxx/PMC2683430.xml | Uveal melanoma presenting as cataract and staphyloma | A 45-year-old lady presented to us with a history of painless swelling in the left eye associated with decrease in vision since six months. On ophthalmic examination, she had a best corrected visual acuity (BCVA) of 20/20 in the right eye and light perception with inaccurate projection of rays in the left eye. The ante... | F | 2009 | [[45.0, "year"]] |
2888 | 2683431-1 | 19384024 | oa_comm/PMC002xxxxxx/PMC2683431.xml | Scheimpflug imaging of pediatric posterior capsule rupture | An 11-year-old boy presented two days following blunt trauma to his left eye caused due to a projectile released from a slingshot. On examination, his best corrected visual acuity (BCVA) was 20/20 in the right eye and 20/400 in the left eye. Slit-lamp biomicroscopy of his left eye revealed a Vossius ring, traumatic cat... | M | 2009 | [[11.0, "year"]] |
2889 | 2683432-1 | 19384019 | oa_comm/PMC002xxxxxx/PMC2683432.xml | Pulsating enophthalmos in association with an orbital varix | A 64-year-old Caucasian woman was referred for an incidentally discovered right orbital mass on computed tomographic (CT) scan. Her ocular history was significant for bilateral trabeculectomies performed for pseudoexfoliative glaucoma. She had noticed that her right eye was sunken-in since childhood but attributed it t... | F | 2009 | [[64.0, "year"]] |
2890 | 2683441-1 | 19384025 | oa_comm/PMC002xxxxxx/PMC2683441.xml | Solitary fibrous tumor of the orbit presenting in pregnancy | A 32-year-old woman, three months pregnant, reported with the complaint of protrusion of the right eye for six months, which had progressed rapidly for the last two months. She also gave history of double vision for the last one month. Extraocular movements were grossly restricted in the right eye. Anterior segment exa... | F | 2009 | [[32.0, "year"]] |
2891 | 2683450-1 | 19384023 | oa_comm/PMC002xxxxxx/PMC2683450.xml | Aicardi syndrome: The importance of an ophthalmologist in its diagnosis | A three-month-old female child was referred to our hospital for evaluation of apparent blindness. There was history of frequent episodes of flexor spasms with twitching of both eyes since one and a half months of age. Each episode recurred nearly five to six times per day associated with drooling of saliva. According t... | F | 2009 | [[3.0, "month"]] |
2950 | 2687102-1 | 19478925 | oa_comm/PMC002xxxxxx/PMC2687102.xml | Changes in Peripheral Anterior Chamber Depth of a Case of Relapsing Polychondritis with Recurrent Secondary Angle Closure Glaucoma | Informed consent was obtained from the patients.
A 54-year-old Japanese female who noted blurred vision in her right eye visited a local ophthalmic clinic in 1999. She was diagnosed with IOP elevation of the right eye due to ACG and was subjected to laser iridotomy. She never showed any signs of intraocular inflammatio... | F | 2008-01-04 | [[54.0, "year"]] |
2951 | 2687104-1 | 19478927 | oa_comm/PMC002xxxxxx/PMC2687104.xml | Two Cases of Severe Degeneration of the Macula Following Vitrectomy with Indocyanine Green-Assisted Internal Limiting Membrane Peeling for Idiopathic Macular Hole | A 63-year-old woman had a stage III macular hole in the right eye and a stage IV in the left eye (Fig. ). She had 6 months history of decreased vision in her right eye and 2 months in her left eye. Her corrected visual acuity was 20/50 OD and 20/30 OS. Phacoemulsification and aspiration, intraocular lens implantation, ... | F | 2008-02-15 | [[63.0, "year"]] |
2952 | 2687104-2 | 19478927 | oa_comm/PMC002xxxxxx/PMC2687104.xml | Two Cases of Severe Degeneration of the Macula Following Vitrectomy with Indocyanine Green-Assisted Internal Limiting Membrane Peeling for Idiopathic Macular Hole | A 55 year-old woman had a stage IV macular hole in her left eye (Fig. ). She had 2 months history of decreased vision in her left eye. Her corrected visual acuity was 20/20 OD and 20/60 OS. Phacoemulsification and aspiration, intraocular lens implantation, and vitrectomy were performed. After injecting 0.5% ICG to stai... | F | 2008-02-15 | [[55.0, "year"]] |
2977 | 2694583-1 | 19517028 | oa_comm/PMC002xxxxxx/PMC2694583.xml | Subconjunctival Emphysema After Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) | An 85 year-old lady with Fuch’s dystrophy had DSAEK surgery on her left eye at our center. She had previous cataract surgery and her intraocular lens was centered in her posterior capsule. Her ophthalmologic and systemic general condition was otherwise normal.
The DSAEK surgery was routine and uneventful. At the end of... | F | 2008-05-23 | [[85.0, "year"]] |
2978 | 2694601-1 | 19517035 | oa_comm/PMC002xxxxxx/PMC2694601.xml | Magnetic Resonance Imaging in Case of Cortical Apex Syndrome Caused by Varicella Zoster Virus | A 71-year-old man, who had colon carcinoma, visited his internist because of headaches and pain around the right eye. Roxoprofen, an anti-inflammatory agent, was prescribed. After 6 days, the patient was referred to our clinic because he was suspected to have early herpes zoster ophthalmicus (HZO). After informing him ... | M | 2008-06-03 | [[71.0, "year"]] |
2979 | 2694607-1 | 19516912 | oa_comm/PMC002xxxxxx/PMC2694607.xml | Regression of Urrets-Zavalia Syndrome After Deep Lamellar Keratoplasty for Keratoconus: A Case Study | A 24 years old man, affected by bilateral keratoconus, was submitted to DLK in the left eye. The preoperative uncorrected visual acuity (UCVA) was 20/600 and the best corrected visual acuity (BCVA) was 20/63; the pachymetry was 378 μm. After peribulbar anaesthesia (Chloride Mepivacaine 2%) and 8 mm / 300 µm trephinatio... | M | 2008-08-08 | [[24.0, "year"]] |
2980 | 2694609-1 | 19516914 | oa_comm/PMC002xxxxxx/PMC2694609.xml | Radiological Pitfalls in Patients with Inducible Dynamic Proptosis | A 29 year old man had been diagnosed with a left facial and orbital low-flow arteriovenous malformation. In the past, he had undergone embolization treatment in 1983, and endoscopic ND Yag laser of the oral cavity with transcutaneous laser of the lower eyelid, cheek and upper lip in 2001. The latter was repeated in 200... | M | 2008-05-05 | [[29.0, "year"]] |
2981 | 2694609-2 | 19516914 | oa_comm/PMC002xxxxxx/PMC2694609.xml | Radiological Pitfalls in Patients with Inducible Dynamic Proptosis | A 24 year old woman was originally referred for consideration to improve facial asymmetry due to progressive right globe enophthalmos with inferior displacement (Fig. ). A diagnosis of neurofibromatosis was made and confirmed as type 1 with spontaneous mutation on the basis of multiple café au lait patches, axillary fr... | F | 2008-05-05 | [[24.0, "year"]] |
3111 | 2712701-1 | 19574700 | oa_comm/PMC002xxxxxx/PMC2712701.xml | Vertical lid split approach for optic nerve sheath decompression | A 34-year-old overweight woman presented with headache and decreased vision in the left eye over a four-month period. No other risk factors were present for idiopathic intracranial hypertension (IIH). On examination, best-corrected visual acuity was 20/40 in the left eye and 20/20 in the right eye. Color vision was aff... | F | 2009 | [[34.0, "year"]] |
3112 | 2712702-1 | 19574701 | oa_comm/PMC002xxxxxx/PMC2712702.xml | Successful management of presumed Candida endogenous endophthalmitis with oral voriconazole | A 73-year-old male, diabetic for 11 years, hypertensive for the past five years and with ischemic heart disease presented with gradually progressive painless loss of vision in the right eye of three weeks duration. He had an indwelling double lumen subclavian catheter and was undergoing dialysis once every three days f... | M | 2009 | [[73.0, "year"]] |
3113 | 2712703-1 | 19574702 | oa_comm/PMC002xxxxxx/PMC2712703.xml | Scleral ulceration after vitreoretinal surgery | A 40-year-old male patient was referred for scleral ulceration following vitreoretinal surgery. He had a previous history of laser photocoagulation for proliferative diabetic retinopathy in both eyes. Patient had a well-controlled insulin-dependent diabetes mellitus. He had a previous history of a diabetic foot problem... | M | 2009 | [[40.0, "year"]] |
3114 | 2712704-1 | 19574703 | oa_comm/PMC002xxxxxx/PMC2712704.xml | Keratouveitis caused by Euphorbia plant sap | A 60-year-old male was trimming his garden hedge E. trigona plant (African milk tree) [] and got sprayed with milky sap into his right eye (RE). He had an immediate burning sensation and pain which was relieved partially by irrigation with water. After 16 h, he presented to us with pain, burning with gross dimness of v... | M | 2009 | [[60.0, "year"]] |
3115 | 2712704-2 | 19574703 | oa_comm/PMC002xxxxxx/PMC2712704.xml | Keratouveitis caused by Euphorbia plant sap | A 51-year-old man was pruning his overgrown species of E. neriifolia plant (Indian Spurge tree) [] in his garden when he felt some sap enter into his LE. The eye became irritable and was immediately irrigated with tap water.
He presented four hours later. On examination, BCVA in the RE was 20/20 and in the LE 20/40. Th... | M | 2009 | [[51.0, "year"]] |
3116 | 2712704-3 | 19574703 | oa_comm/PMC002xxxxxx/PMC2712704.xml | Keratouveitis caused by Euphorbia plant sap | A 54-year-old woman was pruning her Euphorbia milii (crown-of-thorns) houseplant [] when she felt a stinging sensation as a drop of sap entered her LE. She did not wash her eyes immediately. Fifteen minutes later she felt severe pain, blepharospasm and dimness of vision in the LE.
She presented three hours later and ir... | F | 2009 | [[54.0, "year"]] |
3117 | 2712705-1 | 19574704 | oa_comm/PMC002xxxxxx/PMC2712705.xml | Aniridia associated with congenital aphakia and secondary glaucoma | A 35-year-old male presented with complaints of decreased vision in both eyes for 15 years. There was no history of intraocular surgery in either eye. His best-corrected visual acuity was no perception of light in the right eye and 20/400 in the left eye with + 9.0 diopter sphere (Dsph). Horizontal pendular nystagmus w... | M | 2009 | [[35.0, "year"]] |
3118 | 2712706-1 | 19574705 | oa_comm/PMC002xxxxxx/PMC2712706.xml | Vision recovery in human immunodeficiency virus-infected patients with optic neuropathy treated with highly active antiretroviral therapy: A case series | A 30-year-old retrovirus positive male was referred for a bilateral slowly deteriorating vision over a six-month period. His CD4 and absolute lymphocyte counts at the time of referral were 120 cells × 106/L and 2300 cells/mm3, respectively. At the time of presentation, he was on a combination of trimethoprim and sulpha... | M | 2009 | [[30.0, "year"]] |
3119 | 2712706-2 | 19574705 | oa_comm/PMC002xxxxxx/PMC2712706.xml | Vision recovery in human immunodeficiency virus-infected patients with optic neuropathy treated with highly active antiretroviral therapy: A case series | A 13-year-old retrovirus positive girl was referred to us for a routine ophthalmic evaluation. At the time of examination, she was unaware of the poor vision in the left eye. Her BCVA was 20/30 and counting fingers close to the face in the right eye and the left eye, respectively. Relative afferent pupillary defect was... | F | 2009 | [[13.0, "year"]] |
3120 | 2712706-3 | 19574705 | oa_comm/PMC002xxxxxx/PMC2712706.xml | Vision recovery in human immunodeficiency virus-infected patients with optic neuropathy treated with highly active antiretroviral therapy: A case series | A 31-year-old retrovirus positive male complained of decrease in vision in both eyes. His BCVA in both eyes was hand movements close to face. CD4 count was 189 cells × 106/L. Mild optic disc pallor was noted in both eyes. There was no relative afferent pupillary defect. Visual fields could not be done due to the poor v... | M | 2009 | [[31.0, "year"]] |
3121 | 2712707-1 | 19574706 | oa_comm/PMC002xxxxxx/PMC2712707.xml | Schwannoma of the eyelid: Apropos of two cases | A 47-year-old man was referred to us with a one-year history of a slowly enlarging, painless nodule on his right lower eyelid. Ocular examination was normal except for the presence of a firm, non-tender nodule measuring 7 × 7 × 6mm in the medial third of the right lower eyelid. There were no clinical findings indicativ... | M | 2009 | [[47.0, "year"]] |
3122 | 2712707-2 | 19574706 | oa_comm/PMC002xxxxxx/PMC2712707.xml | Schwannoma of the eyelid: Apropos of two cases | A 20-year-old woman was referred to us for a chalazion of her left lower eyelid, which had been operated three times in four years. No tissues had been submitted for histopathological examination in earlier surgical procedures. Ocular examination was normal except for the presence of a firm, non-tender painless nodule ... | F | 2009 | [[20.0, "year"]] |
3123 | 2712708-1 | 19574707 | oa_comm/PMC002xxxxxx/PMC2712708.xml | Fibrinous anterior uveitis following laser in situ keratomileusis | A 29-year-old woman underwent uncomplicated LASIK in both eyes for low myopic astigmatism. Prior systemic and ocular history was unremarkable. Preoperative refractive error was −3.00 diopter sphere (D Sph) / −1.00 diopter cylinder (D Cyl) × 180° in the right eye and −2.75 D Sph/ −1.00 D Cyl × 180° in the left eye. On h... | F | 2009 | [[29.0, "year"]] |
4610 | 2796640-1 | 20003290 | oa_comm/PMC002xxxxxx/PMC2796640.xml | Self-inflicted penetrating eye injuries using a razor blade: Case report | A 23 year old man was referred from the emergency department with sudden bilateral eye pain and visual loss. On further history, he had been made redundant at work that day, and had proceeded to 'try and blind' himself as a result. He had first poured alcohol over eyes, which was unsuccessful. He had then super-glued h... | M | 2009 | [[23.0, "year"]] |
4901 | 2804128-1 | 19700878 | oa_comm/PMC002xxxxxx/PMC2804128.xml | Ophthalmic complications including retinal detachment in hyperimmunoglobulinemia E (Job's) syndrome: Case report and review of literature | A 15-year-old male child had watering, irritation, and itching in both eyes of two years duration. He noticed dimness of vision in his left eye one year ago. Patient denied any history of trauma in the left eye. On presentation patient had visual acuity of 20/20 in the right eye and perception of light with inaccurate ... | M | 2009 | [[15.0, "year"]] |
4902 | 2804130-1 | 19700880 | oa_comm/PMC002xxxxxx/PMC2804130.xml | An unusual case of total ophthalmoplegia | An eight-year-old male child attended the outpatient department, complaining of drooping of the left eyelid [] with a history of penetrating injury of the hard palate by an iron spoon seven days back. The injury had occurred while the child had fallen down with the spoon in his mouth. The iron spoon had already been re... | M | 2009 | [[8.0, "year"]] |
4903 | 2804131-1 | 19700881 | oa_comm/PMC002xxxxxx/PMC2804131.xml | Primary primitive neuroectodermal tumor of the orbit | An eight-year-old female child was brought to our outpatient department for progressing protrusion of the left eye ball for two months. There was associated diplopia with restriction of ocular movements superiorly and laterally. There was minimal ptosis and she had ocular pain over a period of four weeks. There was no ... | F | 2009 | [[8.0, "year"]] |
4904 | 2804132-1 | 19700882 | oa_comm/PMC002xxxxxx/PMC2804132.xml | Multiple myeloma presenting as bilateral orbital proptosis | A 58-year-old-man presented with painful rapidly progressive bilateral proptosis with restricted ocular movements of 15 days duration. There was history of about 10-kg weight loss amounting to 15% of his body weight over a period of the past one month. Ophthalmic examination revealed visual acuity of 20/30 in both eyes... | M | 2009 | [[58.0, "year"]] |
4905 | 2804133-1 | 19700883 | oa_comm/PMC002xxxxxx/PMC2804133.xml | Multimodality treatment approach in management of primary peripheral primitive neuroectodermal tumor of the orbit | A two-year-old male child presented with history of progressive prominence of the right eye for the past three months. On external ocular examination there was an upward and lateral deviation of the right eye with eccentric proptosis. The child was not cooperative for visual assessment. Anterior segment examination of ... | M | 2009 | [[2.0, "year"]] |
4906 | 2804134-1 | 19700884 | oa_comm/PMC002xxxxxx/PMC2804134.xml | Mefenamic acid-induced bilateral transient myopia, secondary angle closure glaucoma and choroidal detachment | A 30-year-old male patient presented to us with diminution of vision, associated with pain, and colored haloes in both eyes for two days. He had been suffering from headache for one week before presentation for which he was prescribed meftal tablet 500 mg (mefenamic acid, Blue Cross Laboratories Ltd, India) by a local ... | M | 2009 | [[30.0, "year"]] |
4907 | 2804135-1 | 19700885 | oa_comm/PMC002xxxxxx/PMC2804135.xml | An unusual intraorbital foreign body: A brake lever | A 25-year-old man presented to our emergency clinic 6 h after a penetrating orbital injury with a brake lever in his right lower eyelid during a motorcycle accident []. Both eyelids were echymotic and edematous. On examination, he had no light perception in the affected eye and 20/20 in the fellow eye. The left eye was... | M | 2009 | [[25.0, "year"]] |
5039 | 2812767-1 | 19861750 | oa_comm/PMC002xxxxxx/PMC2812767.xml | Amyloidosis of lacrimal gland | A 45-year-old Indian woman presented with a slowly progressive swelling of the left upper eyelid of three months duration. This was associated with discomfort but was not painful. On examination, the best-corrected visual acuity was 20/20 in both eyes. Left eye examination showed lateral ptosis with S-shaped deformity ... | F | 2009 | [[45.0, "year"]] |
5040 | 2812768-1 | 19861751 | oa_comm/PMC002xxxxxx/PMC2812768.xml | Botulinum toxin in the management of acquired motor fusion deficiency | A 30-year-old lady presented to the squint clinic with complaints of constant diplopia and outward deviation of the right eye following head trauma three years back in a road accident. Prior to the accident, she had never had diplopia or squinting of the eyes. She had developed bilateral sensorineural hearing loss foll... | F | 2009 | [[30.0, "year"]] |
5041 | 2812769-1 | 19861752 | oa_comm/PMC002xxxxxx/PMC2812769.xml | A rare cause of nasolacrimal duct obstruction: Dentigerous cyst in the maxillary sinus | An 11-year-old male child was referred to us for epiphora. He had intermittent mucoid discharge from the inner canthus of the left eye for the last one year. Ocular and medical histories were normal. On examination, his best-corrected visual acuity was 20/20 in both eyes. Pupillary reflexes and extraocular movements we... | M | 2009 | [[11.0, "year"]] |
5042 | 2812771-1 | 19861754 | oa_comm/PMC002xxxxxx/PMC2812771.xml | Bilateral macular hole secondary to remote lightning strike | A 16-year-old girl presented to us with sudden painless diminution of vision in the right eye (RE) following a lightning strike while sleeping in the house on the ground at night two months ago (April 2008). Her brother-in-law, who was sleeping approximately six feet away died immediately but this girl survived and exp... | F | 2009 | [[16.0, "year"]] |
5043 | 2812772-1 | 19861755 | oa_comm/PMC002xxxxxx/PMC2812772.xml | Insect wing tarsal foreign body causing conjunctival granuloma and marginal keratitis | A 37-year-old male was referred with a diagnosis of episcleritis with peripheral keratitis to our center for further management. He had a history of increasing ocular discomfort in the right eye of one week duration. He was not on any medicines at the time of presentation. On examination, his best-corrected visual acui... | M | 2009 | [[37.0, "year"]] |
5044 | 2812773-1 | 19861756 | oa_comm/PMC002xxxxxx/PMC2812773.xml | Congenital orbital teratoma presenting as microphthalmos with cyst | A seven-month-old female child presented with history of mass lesion in the left lower lid since birth which was progressively increasing in size. Examination revealed a swelling in the lateral two-third of left lower lid, bluish in color and measuring 3 × 3 cm. The swelling was soft, fluctuant, with ill-defined border... | F | 2009 | [[7.0, "month"]] |
5067 | 2813577-1 | 20142959 | oa_comm/PMC002xxxxxx/PMC2813577.xml | Neuro-ophthalmic Afferent System Diagnoses A General Ophthalmologist Should (Almost) Never Make Alone | A 55-year-old man with hypertension and diabetes presents with new awareness of blurred vision OD for two months. The visual acuity was 20/25 OD and 20/20 OS. Goldmann perimetry demonstrated an inferior altitudinal visual field loss OD. The pupil examination showed a relative afferent pupillary defect (RAPD) OD. Ophtha... | M | 2009 | [[55.0, "year"]] |
5068 | 2813577-2 | 20142959 | oa_comm/PMC002xxxxxx/PMC2813577.xml | Neuro-ophthalmic Afferent System Diagnoses A General Ophthalmologist Should (Almost) Never Make Alone | A 65-year-old woman with hypertension and diabetes presents with new awareness of blurred vision OD for two days. The visual acuity was 20/40 OD and 20/20 OS. No visual field is performed. The pupil examination showed a relative afferent pupillary defect (RAPD) OD. Ophthalmoscopy showed a normal optic nerve OD. The rem... | F | 2009 | [[65.0, "year"]] |
5069 | 2813577-3 | 20142959 | oa_comm/PMC002xxxxxx/PMC2813577.xml | Neuro-ophthalmic Afferent System Diagnoses A General Ophthalmologist Should (Almost) Never Make Alone | A 25-year-old woman presents with chronic and unresolved loss of vision OD that occurred acutely two months prior to presentation. There is a right RAPD, a central scotoma OD on visual field testing, and a normal optic disc. Computed tomography (CT) scan of the head in the emergency room was normal. A diagnosis of chro... | F | 2009 | [[25.0, "year"]] |
5070 | 2813577-4 | 20142959 | oa_comm/PMC002xxxxxx/PMC2813577.xml | Neuro-ophthalmic Afferent System Diagnoses A General Ophthalmologist Should (Almost) Never Make Alone | A 30-year-old man presents with acute onset of unilateral optic disc edema with a macular star figure of exudate OD. The vision was 20/200 OD, there is right RAPD, and a cecocentral scotoma on visual field testing OD. There is mild vitreous cell OD. The ophthalmologist writes'“papilledema” on the chart and refers the p... | M | 2009 | [[30.0, "year"]] |
5071 | 2813577-5 | 20142959 | oa_comm/PMC002xxxxxx/PMC2813577.xml | Neuro-ophthalmic Afferent System Diagnoses A General Ophthalmologist Should (Almost) Never Make Alone | A 14-year-old girl presents with headache, visual loss to counting fingers vision, and severe bilateral disc edema with macular star figure OU. The outside ophthalmologist makes the diagnosis of “bilateral neuroretinitis” due to cat scratch disease and sends the Bartonella titer. There is an incomitant esotropia and th... | F | 2009 | [[14.0, "year"]] |
5072 | 2813577-6 | 20142959 | oa_comm/PMC002xxxxxx/PMC2813577.xml | Neuro-ophthalmic Afferent System Diagnoses A General Ophthalmologist Should (Almost) Never Make Alone | A 60-year-old male judge with hypertension and diabetes describes a single episode of monocular transient visual loss OD. A dark curtain descended from superior to inferior OD, lasted 10 minutes and then spontaneously resolved. The patient was seen by an outside ophthalmologist and a diagnosis of “retinal migraine” was... | M | 2009 | [[60.0, "year"]] |
5073 | 2813589-1 | 20142970 | oa_comm/PMC002xxxxxx/PMC2813589.xml | Late Occurrence of Lens Particle Glaucoma Due to an Occult Glass Intralenticular Foreign Body | A 22-year-old man presented to our hospital with complaints of acute pain and redness in the right eye with headache centered over the right side of the head of 2 days' duration. He gave history of trauma inflicted 11 years ago with corneal repair done at that time. No documented evidence of the trauma or surgery perfo... | M | 2009 | [[22.0, "year"]] |
5074 | 2813592-1 | 20142969 | oa_comm/PMC002xxxxxx/PMC2813592.xml | Traditional Medicine in Oman: Its Role in Ophthalmology | A 35-year-old lady, who worked in the royal stable, presented with redness and decreased vision in her right eye of 15 days duration. She was initially treated at a local health center for a corneal abrasion in her right eye, after being hit by the tail of a horse while cleaning the stable. She applied honey three time... | F | 2009 | [[35.0, "year"]] |
5075 | 2813592-2 | 20142969 | oa_comm/PMC002xxxxxx/PMC2813592.xml | Traditional Medicine in Oman: Its Role in Ophthalmology | A five-year-old female, child of a medical assistant working in a tertiary care teaching hospital in the Sultanate of Oman, underwent bilateral routine uneventful cataract extraction and posterior chamber intraocular lens implantation for congenital cataracts. She presented with painful red eyes two weeks post-surgery.... | F | 2009 | [[5.0, "year"]] |
End of preview. Expand in Data Studio
LEME Ophthalmology Corpus
This repository contains ophthalmology-specific subsets selected from the Meditron clinical guidelines, MedRAG/StatPearls, and PMC-Patients-V2 source corpora. These filtered subsets were used to construct instruction data for LEME.
| Configuration | Entries | Content |
|---|---|---|
guidelines |
3,435 | Ophthalmology-related guideline snippets |
statpearls |
12,919 | Ophthalmology-related StatPearls snippets |
cases |
5,745 | Published ophthalmology case summaries from PMC-Patients-V2 |
| Total | 22,099 | Snippets and case summaries |
Loading
from datasets import load_dataset
guidelines = load_dataset("Yale-BIDS-Chen/LEME-Corpus", "guidelines", split="train")
statpearls = load_dataset("Yale-BIDS-Chen/LEME-Corpus", "statpearls", split="train")
cases = load_dataset("Yale-BIDS-Chen/LEME-Corpus", "cases", split="train")
Format and provenance
Guidelines and StatPearls have id and text fields. text preserves each
original string exactly; id is a local row ID. Cases retain the original
string fields, including patient_uid, PMID, title, and patient.
The original age list is losslessly encoded as age_json; recover it
with json.loads(row["age_json"]).
All configurations use the split name train to indicate their corpus
role; this release does not introduce new evaluation partitions. Records from the
LEME corpus archive are preserved in this release.
See provenance.json for original archive members, row counts, and checksums,
and THIRD_PARTY_NOTICES.md for source attribution
and applicable terms. The original archive is linked in the LEME paper.
Contact
For general inquiries, please contact Hyunjae Kim at hyunjae.kim@yale.edu.
License
LEME code, models, data, and other related materials may be used for non-commercial research purposes. Any derivative works must be made publicly available through a public platform, such as GitHub or Hugging Face. For commercial-use inquiries, please contact us (agreements@yale.edu or qingyu.chen@yale.edu). Please see the LICENSE file for the full terms.
The local LICENSE is an unmodified copy of the official GitHub license.
As stated in that license, it applies only to rights held by the licensor;
third-party materials remain subject to their applicable terms. Source
attribution and applicable third-party notices are preserved separately.
Citation
@article{kim2026leme,
title={LEME: open large language models for ophthalmology with advanced reasoning and clinical validation},
author={Kim, Hyunjae and Ai, Xuguang and Srinivasan, Sahana and Gilson, Aidan and Singer, Maxwell B and Pushpanathan, Krithi and Xie, Qianqian and Park, Jungwoo and Applebaum, Serina and Yang, Gabriel Dawei and others},
journal={npj Digital Medicine},
year={2026},
publisher={Nature Publishing Group UK, London}
}
- Downloads last month
- 30