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open-ended
<image>What lesions are present in the retinal fundus of the left eye showing moderate non-proliferative diabetic retinopathy? This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Microaneurysm</type><location>Peripheral Nasal</location></lesion><lesion><type>Soft Exudate</type><location>Peripheral Inferior, Outer Superior</location></lesion><lesion><type>Hemorrhage</type><location>Inner Inferior, Outer Inferior</location></lesion>
<reason>The question asks which lesions are visible in a left-eye fundus image with moderate non-proliferative diabetic retinopathy, so the image should be examined for typical diabetic retinopathy lesions, including microaneurysms, hemorrhages, and ischemic/exudative changes. Small red dot-like lesions are identified ...
<answer>Microaneurysms, soft exudates, and haemorrhages are present.</answer>
images/img_000001.png
2
open-ended
<image>Based on the retinal findings in this image, what is the diagnosis and how is the patient's central vision likely to be affected? This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Hemorrhage</type><location>Central Fovea</location></lesion>
<reason>The question asks for both the diagnosis and the likely impact on central vision, so the key finding is whether the lesion involves the macular center. In this image, hemorrhage is located at the central fovea, which is the most critical area for sharp central vision. In the setting of AMD, foveal hemorrhage su...
<answer>The diagnosis is age-related macular degeneration with central foveal hemorrhage. Because the hemorrhage involves the fovea, the patient’s central vision is likely to be significantly affected, causing reduced central visual acuity and possible visual distortion.</answer>
images/img_000002.jpg
3
open-ended
<image>What is the retinopathy grade observed in the left eye fundus image, and what does it imply regarding the severity and progression of diabetic retinopathy? This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Microaneurysm</type><location>Peripheral Nasal, Peripheral Superior, Peripheral Temporal, Outer Nasal, Outer Superior</location></lesion><lesion><type>Hemorrhage</type><location>Peripheral Superior, Peripheral Temporal, Outer Nasal, Outer Superior</location></lesion>
<reason>The question asks for the retinopathy grade and its clinical implication, so the image should be evaluated for diabetic retinopathy lesions and their distribution. Microaneurysms are present in multiple regions, including the peripheral nasal, peripheral superior, peripheral temporal, outer nasal, and outer sup...
<answer>The retinopathy grade is DR grade 2, consistent with moderate non-proliferative diabetic retinopathy. This indicates established diabetic retinal vascular damage with multiple microaneurysms and hemorrhages, but without proliferative neovascularization. The disease is more than mild and requires monitoring beca...
images/img_000004.jpg
4
open-ended
<image>What are the key lesions observed in this fundus image? This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Scar</type><location>Central Fovea</location></lesion>
<reason>The question asks for the key visible lesion rather than the final disease diagnosis, so the image should be summarized based on the annotated retinal abnormality and its location. The main lesion identified is a scar located at the central fovea. Because the central fovea is the anatomical center of the macula...
<answer>A scar is observed at the central fovea.</answer>
images/img_000005.jpg
5
open-ended
<image>Please analyze this retinal image clinically. This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Cup-to-disc Ratio</type><location>Optic Cup, Optic Disc</location></lesion>
<reason>The image should be assessed systematically, including the optic nerve head, macula, retinal vessels, and peripheral retina. The retinal background appears largely unremarkable, with no visible hemorrhages, microaneurysms, hard exudates, cotton-wool spots, drusen, or atrophic lesions. The macular region and ret...
<answer>The fundus image is otherwise largely normal, with no obvious retinal vascular, macular, hemorrhagic, or exudative lesions. The key finding is an increased cup-to-disc ratio involving the optic cup and optic disc, which suggests possible glaucoma risk and requires further optic nerve evaluation.</answer>
images/img_000006.jpg
6
open-ended
<image>Describe the location and clinical significance of the lesion shown in this fundus image. This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Atrophy</type><location>Outer Nasal</location></lesion>
<reason>The question asks for both the lesion location and its clinical significance, so the key is to identify the lesion type and determine whether it involves the macular center. The annotated lesion is atrophy located in the outer nasal region. This indicates localized retinal or chorioretinal tissue loss outside t...
<answer>A focal atrophic lesion is present in the outer nasal retina. Since it is outside the central fovea, it is unlikely to directly threaten central vision, but it indicates localized retinal or chorioretinal degeneration that should be clinically monitored.</answer>
images/img_000007.jpg
7
open-ended
<image>Please analyze this retinal image clinically. This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Tigroid Fundus</type><location>entire retina</location></lesion>
<reason>The question asks for a clinical analysis of the retinal image, so the overall fundus appearance should be assessed rather than focusing only on focal lesions. The annotated finding is a tigroid fundus pattern involving the entire retina. This appearance reflects diffuse thinning of the retinal pigment epitheli...
<answer>The fundus image shows a diffuse tigroid fundus pattern involving the entire retina, suggesting high myopia-related fundus change. </answer>
images/img_000008.jpg
8
open-ended
<image>What abnormalities are visible in this retinal image? This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Atrophy</type><location>Outer Inferior</location></lesion><lesion><type>Tigroid Fundus</type><location>entire retina</location></lesion>
<reason>The question asks what abnormalities are visible in the retinal image, so the response should focus on the annotated lesion types and their locations. The image shows a tigroid fundus pattern involving the entire retina, which suggests diffuse retinal and choroidal thinning with increased visibility of the unde...
<answer>The visible abnormalities include diffuse tigroid fundus changes involving the entire retina and focal atrophy in the outer inferior region. These findings are consistent with pathological myopia or high myopia-related chorioretinal degeneration.</answer>
images/img_000009.jpg
9
open-ended
<image>What is the retinopathy grade diagnosed in the left eye based on the retinal fundus analysis? This is an open-ended question. Please output its answer with a detailed reason and corresponding visual location.
<lesion><type>Hard Exudate</type><location>Inner Inferior, Inner Nasal, Inner Superior, Peripheral Nasal, Peripheral Temporal, Outer Inferior, Outer Nasal, Outer Superior</location></lesion><lesion><type>Microaneurysm</type><location>Central Fovea, Inner Temporal</location></lesion><lesion><type>Hemorrhage</type><locat...
<reason>The question asks for the diabetic retinopathy grade in the left eye, so the image should be evaluated for the type, extent, and severity of diabetic retinal lesions. Multiple hard exudates are present across the inner, outer, and peripheral retinal regions, indicating retinal vascular leakage. Microaneurysms a...
<answer>The left eye is diagnosed as moderate non-proliferative diabetic retinopathy, corresponding to ICDR grade 2. This is supported by microaneurysms, multi-regional hemorrhages, and widespread hard exudates, without evidence of proliferative neovascularization.</answer>
images/img_000010.jpg
10
open-ended
<image>Describe the pathological features in this fundus image.
<lesion><type>Drusen</type><location>Inner Nasal, Outer Nasal</location></lesion>
<reason>The question asks for the pathological features visible in the fundus image, so the response should focus on the identified lesion type and its retinal location. The annotated abnormalities are drusen located in the inner nasal and outer nasal regions. Drusen appear as yellowish subretinal deposits and are clin...
<answer>The image shows drusen in the inner nasal and outer nasal regions. These yellowish deposits represent degenerative retinal changes and may be associated with age-related macular degeneration. The central fovea is not directly involved based on the provided lesion locations.</answer>
images/img_000011.jpg
11
closed-ended
<image>Is the central fovea directly affected by retinal hemorrhage in this left eye image? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Hemorrhage</type><location>Inner Inferior, Peripheral Inferior, Peripheral Temporal, Outer Inferior</location></lesion>
<reason>The question specifically asks whether retinal hemorrhage directly involves the central fovea. The annotated hemorrhages are located in the inner inferior, peripheral inferior, peripheral temporal, and outer inferior regions. None of these locations correspond to the central fovea. Therefore, although retinal h...
<answer>No</answer>
images/img_000012.jpg
12
closed-ended
<image>In the right eye fundus image, are there exudates present in the inner nasal region consistent with age-related macular degeneration? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Hard Exudate</type><location>Inner Nasal</location></lesion>
<reason>The question asks whether exudates are visible in the inner nasal region of the right eye fundus image. On visual inspection, a bright yellow-white exudative deposit is seen in the inner nasal region, which is consistent with a hard exudate. This finding directly matches the queried retinal region and lesion ty...
<answer>Yes</answer>
images/img_000013.jpg
13
closed-ended
<image>Does the fundus report show any signs of glaucoma in the optic disc region of the right eye? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>None</type><location>None</location></lesion>
<reason>The question asks whether the optic disc region of the right eye shows signs suggestive of glaucoma. In the image, the optic disc does not show obvious glaucomatous changes: the optic cup does not appear abnormally enlarged, the neuroretinal rim is not visibly thinned or notched, and there is no clear optic dis...
<answer>No</answer>
images/img_000014.jpg
14
closed-ended
<image>Does the right eye show atrophy in the nasal region near the optic disc with involvement of the optic disc and sparing of the macula? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Atrophy</type><location>Peripheral Nasal, Outer Nasal</location></lesion>
<reason>The question asks whether the right eye shows nasal atrophy near the optic disc, with the macula spared. In the image, atrophic changes are visible in the nasal retina, involving the peripheral nasal and outer nasal regions. This distribution is on the optic-disc side of the fundus and is separate from the cent...
<answer>Yes</answer>
images/img_000015.jpg
15
closed-ended
<image>Is there any sign of proliferative diabetic retinopathy present in the left eye? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Hard Exudate</type><location>Peripheral Nasal</location></lesion><lesion><type>Microaneurysm</type><location>Central Fovea, Inner Inferior, Inner Nasal, Inner Superior, Inner Temporal, Peripheral Inferior, Peripheral Nasal, Peripheral Superior, Peripheral Temporal, Outer Inferior, Outer Nasal, Outer Super...
<reason>The question asks whether the left eye shows signs of proliferative diabetic retinopathy. In the image, diabetic retinopathy lesions are visible, including a hard exudate in the peripheral nasal region, widespread microaneurysms involving the central fovea, inner, outer, and peripheral retinal regions, and hemo...
<answer>No</answer>
images/img_000016.jpg
16
closed-ended
<image>Does the right eye image show lens media opacities consistent with cataract that affect the entire retina region? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Media Opacity</type><location>entire retina</location></lesion>
<reason>The question asks whether the right eye shows lens media opacity consistent with cataract and whether this opacity affects the retinal view globally. In the image, there is a diffuse media haze that reduces the clarity of the fundus across the entire retinal field rather than being confined to one focal retinal...
<answer>Yes</answer>
images/img_000017.jpg
17
closed-ended
<image>Does the right eye fundus image show typical features of glaucoma (such as an increased cup-to-disc ratio)? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>None</type><location>None</location></lesion>
<reason>The question asks whether the right eye fundus image shows typical glaucomatous features, especially an increased cup-to-disc ratio. On visual assessment, the optic disc region does not show obvious glaucomatous change: the optic cup does not appear enlarged, the neuroretinal rim is not visibly thinned or notch...
<answer>No</answer>
images/img_000018.jpg
18
closed-ended
<image>Is there an atrophic lesion involving the outer temporal region adjacent to the optic disc in this left eye fundus image? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Atrophy</type><location>Outer Temporal</location></lesion><lesion><type>Tigroid Fundus</type><location>entire retina</location></lesion>
<reason>The question asks whether an atrophic lesion is present in the outer temporal region adjacent to the optic disc. In the image, a focal area of chorioretinal atrophy is visible in the outer temporal region, which corresponds to the queried location. The fundus also shows a diffuse tigroid pattern throughout the ...
<answer>Yes</answer>
images/img_000019.jpg
19
closed-ended
<image>Based on the fundus findings, does the left eye show signs of proliferative diabetic retinopathy? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Microaneurysm</type><location>Inner Nasal, Outer Nasal, Outer Superior</location></lesion><lesion><type>Hemorrhage</type><location>Inner Nasal, Inner Superior, Outer Nasal</location></lesion>
<reason>The question asks whether the left eye shows signs of proliferative diabetic retinopathy. In the image, diabetic retinopathy changes are visible, including microaneurysms in the inner nasal, outer nasal, and outer superior regions, as well as hemorrhages in the inner nasal, inner superior, and outer nasal regio...
<answer>No</answer>
images/img_000020.jpg
20
closed-ended
<image>Are there drusen lesions located in the Outer Superior region of the right retina? This is a closed-ended question. Please output its answer (yes or no) with a detailed reason and corresponding visual location.
<lesion><type>Drusen</type><location>Outer Inferior, Outer Superior</location></lesion>
<reason>The question asks whether drusen are present specifically in the Outer Superior region of the right retina. In the fundus image, the Outer Superior region refers to the superior part of the outer macular/perifoveal ring, located above the macular center and farther from the fovea than the inner retinal ring. On...
<answer>Yes</answer>
images/img_000021.jpg
21
single-choice
<image>Which retinal region contains the scar lesion seen in this right-eye fundus image? <choices>: ['Central Fovea', 'Optic Disc', 'Peripheral Retina', 'Macula'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding visual location.
<lesion><type>Scar</type><location>Central Fovea</location></lesion>
<reason>The question asks which retinal region contains the visible scar lesion. In the fundus image, the scar is seen at the central macular area, corresponding to the foveal center rather than the optic disc or peripheral retina. Although the macula is a broader anatomical region, the lesion is specifically centered ...
<answer>Central Fovea</answer>
images/img_000023.jpg
22
single-choice
<image>What is the most likely diagnosis suggested by the fundus image? <choices>: ['Cataract', 'Diabetic retinopathy', 'Age-related macular degeneration', 'Normal'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding visual location.
<lesion><type>Media Opacity</type><location>entire retina</location></lesion>
<reason>The question asks for the most likely diagnosis among cataract, diabetic retinopathy, age-related macular degeneration, and normal. In the fundus image, the main abnormality is diffuse haziness and reduced clarity across the entire retinal field, which is consistent with media opacity. The optic disc and optic ...
<answer>Cataract</answer>
images/img_000024.jpg
23
single-choice
<image>Based on the right-eye fundus image, what is the most likely clinical assessment regarding glaucoma risk? <choices>: ['Normal optic disc with low glaucoma risk', 'Suspected early glaucoma', 'Advanced glaucoma', 'Optic disc edema (papilledema)'] This is a single-choice question. Please output its answer (an optio...
<lesion><type>No lesion</type><location>Not specified</location></lesion>
<reason>The question asks which option best describes the glaucoma risk based on the right-eye optic disc appearance. In the image, the optic disc does not show obvious glaucomatous changes: the optic cup is not visibly enlarged, the cup-to-disc ratio does not appear increased, and there is no clear neuroretinal rim th...
<answer>Normal optic disc with low glaucoma risk</answer>
images/img_000025.jpg
24
single-choice
<image>Which retinal region contains the atrophic lesion observed in this right eye fundus image? <choices>: ['Outer Nasal', 'Macula (Central Fovea)', 'Temporal', 'Superior Peripapillary'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding visual location.
<lesion><type>Atrophy</type><location>Outer Nasal</location></lesion>
<reason>The question asks which retinal region contains the visible atrophic lesion. In the right-eye fundus image, the atrophic area is located on the nasal side of the outer retinal region, away from the central fovea. It is not centered in the macula, not simply described as temporal, and not best localized to the s...
<answer>Outer Nasal</answer>
images/img_000026.jpg
25
single-choice
<image>What is the ICDR grade of the diabetic retinopathy found in the right eye? <choices>: ['Mild non-proliferative diabetic retinopathy (ICDR grade 1)', 'Moderate non-proliferative diabetic retinopathy (ICDR grade 2)', 'Severe non-proliferative diabetic retinopathy (ICDR grade 3)', 'Proliferative diabetic retinopath...
<lesion><type>Soft Exudate</type><location>Peripheral Superior, Peripheral Temporal</location></lesion><lesion><type>Microaneurysm</type><location>Peripheral Temporal, Outer Temporal</location></lesion><lesion><type>Hemorrhage</type><location>Inner Inferior, Peripheral Inferior, Peripheral Superior, Peripheral Temporal...
<reason>The question asks for the ICDR grade of diabetic retinopathy in the right eye. In the image, several diabetic retinopathy lesions are visible: microaneurysms are present in the peripheral temporal and outer temporal regions, and retinal hemorrhages are distributed across multiple regions, including the inner in...
<answer>Moderate non-proliferative diabetic retinopathy (ICDR grade 2)</answer>
images/img_000027.jpg
26
single-choice
<image>Which retinal region contains the exudate lesion in the left eye image? <choices>: ['Outer Nasal', 'Macula (Central Fovea)', 'Optic Disc', 'Inner Temporal'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding visual location.
<lesion><type>Hard Exudate</type><location>Outer Nasal</location></lesion>
<reason>The question asks which retinal region contains the exudate lesion in the left eye image. In the image, a bright yellow-white hard exudate is visible in the outer nasal retina. This location is away from the central fovea and optic disc, and it does not correspond to the inner temporal region. Therefore, among ...
<answer>Outer Nasal</answer>
images/img_000028.jpg
27
single-choice
<image>Based on the appearance of the optic disc and cup in this right-eye fundus image, which statement is correct? <choices>: ['Cup-to-disc ratio is within normal limits with no signs of glaucoma', 'Enlarged optic cup consistent with glaucoma', 'Blurred disc margins suggesting optic neuritis', 'Disc hemorrhage is pre...
<lesion><type>None</type><location>None</location></lesion>
<reason>The question asks which statement best describes the optic disc and optic cup in the right-eye fundus image. The optic cup does not appear abnormally enlarged relative to the optic disc, and the cup-to-disc ratio appears within normal limits. The neuroretinal rim is preserved without obvious focal thinning or n...
<answer>Cup-to-disc ratio is within normal limits with no signs of glaucoma</answer>
images/img_000029.jpg
28
single-choice
<image>Based on the fundus appearance of the left eye, what is the most likely diagnosis? <choices>: ['Pathologic Myopia', 'Diabetic Retinopathy', 'Age-related Macular Degeneration', 'Normal Fundus'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding visual l...
<lesion><type>Atrophy</type><location>Outer Nasal</location></lesion><lesion><type>Tigroid Fundus</type><location>entire retina</location></lesion>
<reason>The question asks for the most likely diagnosis based on the visible fundus appearance. The image shows a diffuse tigroid fundus pattern involving the entire retina, suggesting generalized retinal and choroidal thinning. In addition, focal atrophic change is visible in the outer nasal region, indicating localiz...
<answer>Pathologic Myopia</answer>
images/img_000030.jpg
29
single-choice
<image>What is the most likely diagnosis in this right-eye fundus image? <choices>: ['Age-Related Macular Degeneration (AMD)', 'Diabetic Retinopathy', 'Central Retinal Vein Occlusion (CRVO)', 'Normal Fundus'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding...
<lesion><type>Hemorrhage</type><location>Central Fovea</location></lesion>
<reason>The question asks for the most likely diagnosis based on the macular abnormality. The image shows a hemorrhagic lesion involving the central fovea, indicating direct macular involvement. In an older-patient fundus context, foveal or submacular hemorrhage is clinically concerning for active age-related macular d...
<answer>Age-Related Macular Degeneration (AMD)</answer>
images/img_000031.jpg
30
single-choice
<image>What is the most likely diagnosis for this right eye fundus image? <choices>: ['Pathologic Myopia', 'Normal', 'Diabetic Retinopathy', 'Age-related Macular Degeneration'] This is a single-choice question. Please output its answer (an option) with a detailed reason and corresponding visual location.
<lesion><type>Atrophy</type><location>Outer Nasal</location></lesion>
<reason>The question asks for the most likely diagnosis in the right-eye fundus image. The image shows a focal atrophic lesion in the outer nasal retina, suggesting localized chorioretinal degeneration. This type of atrophic change is commonly seen in myopic degenerative fundus changes, especially when it occurs outsid...
<answer>Pathologic Myopia</answer>
images/img_000032.jpg
31
multi-choice
<image>What are the types of lesions identified in the left eye as per the analysis? <choices>: ['Hard Exudates', 'Microaneurysms', 'Hemorrhage', 'Cotton Wool Spots', 'Retinal Detachment'] This is a multi-choice question. Please output its answer (some options) with a detailed reason and corresponding visual location.
<lesion><type>Hard Exudate</type><location>Central Fovea, Inner Inferior, Inner Nasal, Inner Superior, Inner Temporal, Peripheral Inferior, Peripheral Nasal, Peripheral Superior, Peripheral Temporal, Outer Inferior, Outer Nasal, Outer Superior</location></lesion><lesion><type>Microaneurysm</type><location>Inner Inferio...
<reason>The question asks which lesion types are present in the left-eye fundus image. The image shows bright yellow-white hard exudates distributed widely, including the central fovea, inner retinal regions, peripheral regions, and outer retinal regions. Small red dot-like microaneurysms are visible in regions such as...
<answer>Hard Exudates, Microaneurysms, Hemorrhage</answer>
images/img_000033.jpg
32
multi-choice
<image>Which of the following findings are present in the right eye fundus image? (select all that apply) <choices>: ['Neovascularization (new vessels) present', 'Hard exudates involving the central fovea', 'Soft exudates present', 'Intra-retinal microvascular abnormalities (IRMA) present', 'Optic disc abnormality/swel...
<lesion><type>Microaneurysm</type><location>Inner Temporal, Outer Inferior, Outer Temporal</location></lesion><lesion><type>Hard Exudate</type><location>Central Fovea, Inner Inferior, Outer Inferior</location></lesion><lesion><type>Hemorrhage</type><location>Peripheral Inferior, Outer Inferior, Outer Superior, Outer Te...
<reason>The question asks which listed findings are present in the right-eye fundus image. The image shows new abnormal vessels in the peripheral superior region, so neovascularization is present. Bright yellow-white hard exudates are visible at the central fovea, as well as in the inner inferior and outer inferior reg...
<answer>Neovascularization (new vessels) present, Hard exudates involving the central fovea, Intra-retinal microvascular abnormalities (IRMA) present</answer>
images/img_000034.png
33
multi-choice
<image>Based on the retinal image for the right eye, which of the following statements are correct regarding the image findings? <choices>: ['There is a scar lesion located in the Central Fovea', 'The optic disc shows signs of abnormality', 'The image indicates age-related macular degeneration (AMD)', 'The macula is un...
<lesion><type>Scar</type><location>Central Fovea</location></lesion>
<reason>The question asks which statements correctly describe the right-eye fundus findings. The image shows a scar lesion located at the central fovea, indicating direct involvement of the macular center. Because the central fovea is part of the macula and is responsible for central vision, the statement that the macu...
<answer>There is a scar lesion located in the Central Fovea, The image indicates age-related macular degeneration (AMD)</answer>
images/img_000035.jpg
34
multi-choice
<image>Which lesion types are reported to involve the central fovea and therefore indicate macular microvascular involvement in this right eye fundus image? <choices>: ['Microaneurysms', 'Hard Exudates', 'Hemorrhage', 'Neovascularization'] This is a multi-choice question. Please output its answer (some options) with a ...
<lesion><type>Hard Exudate</type><location>Peripheral Superior, Peripheral Temporal</location></lesion><lesion><type>Microaneurysm</type><location>Central Fovea, Inner Nasal, Inner Superior, Inner Temporal, Peripheral Inferior, Peripheral Nasal, Peripheral Superior, Peripheral Temporal, Outer Inferior, Outer Nasal, Out...
<reason>The question asks which lesion types involve the central fovea, because lesions at this location indicate macular microvascular involvement. In the image, microaneurysms are present at the central fovea, showing focal diabetic microvascular damage in the macular center. Hemorrhages are also visible at the centr...
<answer>Microaneurysms, Hemorrhage</answer>
images/img_000036.jpg
35
multi-choice
<image>Which of the following statements correctly describe the retinal findings in this left eye fundus image? <choices>: ['Multiple microaneurysms present, totaling 5, mainly in inner and outer temporal regions.', 'Hard exudates present in the macula.', 'Optic disc shows signs of involvement or edema.', 'Foveal/macul...
<lesion><type>Microaneurysm</type><location>Inner Temporal, Outer Temporal</location></lesion>
<reason>The question asks which statements correctly describe the visible retinal findings in the left-eye fundus image. The image shows multiple small red dot-like microaneurysms, mainly distributed in the inner temporal and outer temporal regions, matching the statement that there are multiple microaneurysms, totalin...
<answer>Multiple microaneurysms present, totaling 5, mainly in inner and outer temporal regions., Foveal/macular region shows no significant lesions and low risk to central vision.</answer>
images/img_000037.png
36
multi-choice
<image>Which of the following statements about the optic disc in this right-eye fundus image are correct? <choices>: ['Optic cup and disc boundaries are well-defined', 'Optic cup is abnormally enlarged', 'No evidence of retinal nerve fiber layer damage', 'Findings indicate glaucoma', 'Optic disc position is normal'] Th...
<lesion><type>None</type><location>None</location></lesion>
<reason>The question asks which statements correctly describe the optic disc appearance in the right-eye fundus image. The optic cup and optic disc margins appear clear and well-defined, without visible disc swelling or blurred boundaries. The optic cup does not appear abnormally enlarged, and there is no obvious neuro...
<answer>Optic cup and disc boundaries are well-defined, No evidence of retinal nerve fiber layer damage, Optic disc position is normal</answer>
images/img_000038.jpg
37
multi-choice
<image>Which lesions are observed in the retinal fundus of the right eye with moderate non-proliferative diabetic retinopathy? <choices>: ['Microaneurysms', 'Hemorrhage', 'Neovascularization', 'Cataract', 'Hard Exudates'] This is a multi-choice question. Please output its answer (some options) with a detailed reason an...
<lesion><type>Microaneurysm</type><location>Central Fovea, Inner Inferior, Inner Superior, Inner Temporal, Peripheral Inferior, Peripheral Nasal, Peripheral Superior, Peripheral Temporal, Outer Inferior, Outer Superior, Outer Temporal</location></lesion><lesion><type>Hemorrhage</type><location>Central Fovea, Inner Supe...
<reason>The question asks which lesion types are visible in the right-eye fundus image with moderate non-proliferative diabetic retinopathy. The image shows numerous small red dot-like microaneurysms involving the central fovea, inner retinal regions, peripheral regions, and outer retinal regions. Retinal hemorrhages a...
<answer>Microaneurysms, Hemorrhage</answer>
images/img_000039.jpg
38
multi-choice
<image>Which lesions are noted in the peripheral nasal region of the left eye's retinal fundus? <choices>: ['Microaneurysms', 'Hard Exudates', 'Soft Exudates', 'Haemorrhages', 'No lesions'] This is a multi-choice question. Please output its answer (some options) with a detailed reason and corresponding visual location.
<lesion><type>Microaneurysm</type><location>Inner Inferior, Inner Nasal, Peripheral Superior</location></lesion><lesion><type>Hard Exudate</type><location>Peripheral Nasal, Outer Superior</location></lesion><lesion><type>Soft Exudate</type><location>Peripheral Nasal</location></lesion><lesion><type>Hemorrhage</type><lo...
<reason>The question asks which lesion types are present in the peripheral nasal region of the left-eye fundus. In the image, bright yellow-white hard exudates are visible on the nasal side of the retina, corresponding to the peripheral nasal region. Pale fluffy soft exudates are also seen in the same nasal-side region...
<answer>Hard Exudates, Soft Exudates</answer>
images/img_000040.png
39
multi-choice
<image>Which types of lesions are present in the right eye according to the retinal fundus analysis? <choices>: ['Microaneurysms', 'Hard Exudates', 'Soft Exudates', 'Haemorrhages', 'No lesions observed'] This is a multi-choice question. Please output its answer (some options) with a detailed reason and corresponding vi...
<lesion><type>Microaneurysm</type><location>Inner Inferior, Peripheral Nasal, Peripheral Superior, Outer Inferior, Outer Superior, Outer Temporal</location></lesion><lesion><type>Hard Exudate</type><location>Inner Superior, Peripheral Nasal, Outer Superior</location></lesion><lesion><type>Soft Exudate</type><location>P...
<reason>The question asks which lesion types are present in the right-eye fundus image. The image shows multiple small red dot-like microaneurysms distributed across the inner, peripheral, and outer retinal regions. Bright yellow-white hard exudates are visible in the inner superior, peripheral nasal, and outer superio...
<answer>Microaneurysms, Hard Exudates, Soft Exudates, Haemorrhages</answer>
images/img_000041.png
40
multi-choice
<image>Which of the following statements correctly describe the clinical findings in this fundus image? <choices>: ['Diffuse tigroid fundus changes are present across the entire retina', 'Localized chorioretinal atrophy is present in the inner nasal region', 'The findings are consistent with pathological myopia-related...
<lesion><type>Atrophy</type><location>Inner Nasal</location></lesion><lesion><type>Tigroid Fundus</type><location>entire retina</location></lesion>
<reason>The question asks which statements correctly describe the fundus findings. The image shows a diffuse tigroid fundus pattern involving the entire retina, reflecting generalized retinal and choroidal thinning with increased visibility of the underlying choroidal vessels. In addition, a localized atrophic lesion i...
<answer>Diffuse tigroid fundus changes are present across the entire retina, Localized chorioretinal atrophy is present in the inner nasal region, The findings are consistent with pathological myopia-related fundus degeneration</answer>
images/img_000003.jpg
41
spatial-referring
<image>What finding is located in <box>[689, 285, 736, 316]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>Soft Exudates</type><location>Peripheral Superior, Outer Superior</location></lesion>
<reason>The question provides a bounding box and asks for the lesion inside that specific region, so the task is spatial-referring lesion identification. In the boxed area [689, 285, 736, 316], a pale, fluffy white lesion is visible in the superior retina. This appearance is typical of soft exudates. The region corresp...
<answer>Soft Exudates</answer>
images/img_000042.jpg
42
spatial-referring
<image>Which abnormality is located inside the bounding box <box>[0, 406, 23, 438]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>None</type><location>None</location></lesion>
<reason>This is a spatial-referring question, so the answer should be based on the finding inside the specified bounding box rather than the overall fundus image. The boxed region [0, 406, 23, 438] corresponds to the optic disc area, but no clear pathological abnormality is visible within this region. There is no obvio...
<answer>No lesion</answer>
images/img_000043.jpg
43
spatial-referring
<image>Please determine the lesion visible in <box>[242, 283, 809, 826]</box>. This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>Atrophy</type><location>Optic</location></lesion>
<reason>This is a spatial-referring question, so the answer should focus on the abnormality within the specified bounding box rather than the entire fundus image. The box [242, 283, 809, 826] covers the optic region, where the tissue shows an atrophic appearance with pale retinal. This finding is consistent with atroph...
<answer>Atrophy</answer>
images/img_000044.jpg
44
spatial-referring
<image>What is present in the bounding box <box>[303, 84, 377, 152]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>Soft Exudates</type><location>Peripheral Superior</location></lesion>
<reason>This is a spatial-referring question, so the answer should focus only on the finding inside the specified bounding box. The box [303, 84, 377, 152] is located in the peripheral superior retinal region. Within this highlighted area, there is a pale, fluffy white retinal lesion, which is characteristic of soft ex...
<answer>Soft Exudates</answer>
images/img_000046.jpg
45
spatial-referring
<image>What pathological change is observed in the selected region <box>[64, 449, 232, 627]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>None</type><location>None</location></lesion>
<reason>This is a spatial-referring question, so the answer should be based only on the selected region inside the bounding box. The box [64, 449, 232, 627] does not show a clear pathological retinal finding. There is no visible hemorrhage, exudate, microaneurysm, atrophic change, or other focal lesion within the highl...
<answer>No lesion</answer>
images/img_000047.jpg
46
spatial-referring
<image>What feature is indicated in <box>[0, 381, 143, 551]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>optic disc</type><location>optic disc</location></lesion>
<reason>This is a spatial-referring question, so the answer should identify the structure inside the specified bounding box rather than describe the whole fundus image. The box [0, 381, 143, 551] highlights the optic nerve head region, where the optic disc is visible. The highlighted area corresponds to the pale circul...
<answer>optic disc</answer>
images/img_000048.jpg
47
spatial-referring
<image>What lesion is identified in <box>[703, 475, 730, 506]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>Hard Exudates</type><location>Central Fovea, Inner Nasal</location></lesion>
<reason>This is a spatial-referring question, so the answer should focus on the lesion inside the specified bounding box rather than the overall fundus image. The box [703, 475, 730, 506] highlights a small bright yellow-white deposit in the macular region, involving the central fovea and inner nasal area. This sharply...
<answer>Hard Exudates</answer>
images/img_000050.jpg
48
spatial-referring
<image>What lesion can be observed in <box>[750, 363, 875, 479]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>Hemorrhage</type><location>Outer Temporal</location></lesion>
<reason>This is a spatial-referring question, so the answer should be based on the lesion inside the specified bounding box rather than the overall fundus findings. The box [750, 363, 875, 479] highlights a localized abnormality in the outer temporal retinal region. Within this area, there is a red retinal lesion consi...
<answer>Hemorrhage</answer>
images/img_000051.jpg
49
spatial-referring
<image>What clinical abnormality is found in <box>[893, 379, 941, 402]</box>? This is a spatial-referring question. Please output the lesion type with a detailed reason.
<lesion><type>Soft Exudates</type><location>Peripheral Nasal</location></lesion>
<reason>This is a spatial-referring question, so the answer should focus on the abnormality inside the specified bounding box. The box [893, 379, 941, 402] highlights a small lesion in the peripheral nasal retinal region. The lesion appears as a pale, fluffy white opacity, which is characteristic of soft exudates or co...
<answer>Soft Exudates</answer>
images/img_000052.png
50
spatial-referring
<image>Where are the optic cup and optic disc located in this right-eye fundus image? This is a spatial-referring question. Please provide their bounding box coordinates.
<lesion><type>Optic Cup</type><location>Optic Cup</location><bbox>[480, 753, 660, 939]</bbox></lesion><lesion><type>Optic Disc</type><location>Optic Disc</location><bbox>[448, 704, 688, 966]</bbox></lesion>
<reason>The question asks for the spatial locations of the optic cup and optic disc, so the relevant visual evidence is the annotated bounding boxes around these optic nerve head structures. The optic cup is the central depressed region within the optic disc, while the optic disc is the larger circular optic nerve head...
<answer>The optic cup is located at bounding box [480, 753, 660, 939], and the optic disc is located at bounding box [448, 704, 688, 966].</answer>
images/img_000053.jpg

LEEF 5-Task Subset

This upload package contains a 5-task fundus VQA subset. Image filenames have been re-encoded as sequential anonymous IDs, and public CSV paths do not expose source dataset names or original filenames.

Files

  • metadata.csv: public upload CSV.
  • file_name/: anonymized image files referenced by the CSV file_name column.

Columns

  • id
  • task
  • question
  • lesion
  • reason
  • answer
  • file_name

Task Distribution

  • | task | number |
  • | open-ended | 10 |
  • | closed-ended | 10 |
  • | single-choice| 10 |
  • | multi-choice | 10 |
  • | referring-box| 10 |
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